LOCUS       DAZKCH010000001       114361 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000001 DAZKCH010000000
VERSION     DAZKCH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 114361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 114361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.001"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(188..2374)
                     /locus_tag="ACG84X_000001"
     CDS             complement(188..2374)
                     /locus_tag="ACG84X_000001"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFP9125913.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            2592..3275
                     /locus_tag="ACG84X_000002"
     CDS             2592..3275
                     /locus_tag="ACG84X_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFP9125914.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(3356..4075)
                     /locus_tag="ACG84X_000003"
     CDS             complement(3356..4075)
                     /locus_tag="ACG84X_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFP9125915.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4387..4593)
                     /locus_tag="ACG84X_000004"
     CDS             complement(4387..4593)
                     /locus_tag="ACG84X_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9125916.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            4838..5440
                     /locus_tag="ACG84X_000005"
     CDS             4838..5440
                     /locus_tag="ACG84X_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFP9125917.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            5581..6861
                     /locus_tag="ACG84X_000006"
     CDS             5581..6861
                     /locus_tag="ACG84X_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFP9125918.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            6874..7602
                     /locus_tag="ACG84X_000007"
     CDS             6874..7602
                     /locus_tag="ACG84X_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFP9125919.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(7671..9194)
                     /locus_tag="ACG84X_000008"
     CDS             complement(7671..9194)
                     /locus_tag="ACG84X_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFP9125920.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            9446..10627
                     /locus_tag="ACG84X_000009"
     CDS             9446..10627
                     /locus_tag="ACG84X_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9125921.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(10687..12315)
                     /gene="treC"
                     /locus_tag="ACG84X_000010"
     CDS             complement(10687..12315)
                     /gene="treC"
                     /locus_tag="ACG84X_000010"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFP9125922.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12766..15477)
                     /locus_tag="ACG84X_000011"
     CDS             complement(12766..15477)
                     /locus_tag="ACG84X_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFP9125923.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(15487..16188)
                     /locus_tag="ACG84X_000012"
     CDS             complement(15487..16188)
                     /locus_tag="ACG84X_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9125924.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            16374..16973
                     /locus_tag="ACG84X_000013"
     CDS             16374..16973
                     /locus_tag="ACG84X_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFP9125925.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            17054..18067
                     /locus_tag="ACG84X_000014"
     CDS             17054..18067
                     /locus_tag="ACG84X_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFP9125926.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            18175..19092
                     /gene="rbsK"
                     /locus_tag="ACG84X_000015"
     CDS             18175..19092
                     /gene="rbsK"
                     /locus_tag="ACG84X_000015"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFP9125927.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            19120..19515
                     /gene="rbsD"
                     /locus_tag="ACG84X_000016"
     CDS             19120..19515
                     /gene="rbsD"
                     /locus_tag="ACG84X_000016"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFP9125928.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            19515..20888
                     /locus_tag="ACG84X_000017"
     CDS             19515..20888
                     /locus_tag="ACG84X_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9125929.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            21245..23389
                     /locus_tag="ACG84X_000018"
     CDS             21245..23389
                     /locus_tag="ACG84X_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFP9125930.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(23441..24481)
                     /locus_tag="ACG84X_000019"
     CDS             complement(23441..24481)
                     /locus_tag="ACG84X_000019"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFP9125931.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(24758..26560)
                     /locus_tag="ACG84X_000020"
     CDS             complement(24758..26560)
                     /locus_tag="ACG84X_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9125932.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(26574..27326)
                     /locus_tag="ACG84X_000021"
     CDS             complement(26574..27326)
                     /locus_tag="ACG84X_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9125933.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(27335..27697)
                     /locus_tag="ACG84X_000022"
     CDS             complement(27335..27697)
                     /locus_tag="ACG84X_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFP9125934.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(27873..28745)
                     /locus_tag="ACG84X_000023"
     CDS             complement(27873..28745)
                     /locus_tag="ACG84X_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFP9125935.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(28796..29284)
                     /locus_tag="ACG84X_000024"
     CDS             complement(28796..29284)
                     /locus_tag="ACG84X_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFP9125936.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(29422..30213)
                     /locus_tag="ACG84X_000025"
     CDS             complement(29422..30213)
                     /locus_tag="ACG84X_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFP9125937.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(30268..30876)
                     /locus_tag="ACG84X_000026"
     CDS             complement(30268..30876)
                     /locus_tag="ACG84X_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFP9125938.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(30869..31186)
                     /locus_tag="ACG84X_000027"
     CDS             complement(30869..31186)
                     /locus_tag="ACG84X_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFP9125939.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(31342..32070)
                     /locus_tag="ACG84X_000028"
     CDS             complement(31342..32070)
                     /locus_tag="ACG84X_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFP9125940.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            32229..33110
                     /locus_tag="ACG84X_000029"
     CDS             32229..33110
                     /locus_tag="ACG84X_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9125941.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(33347..34390)
                     /locus_tag="ACG84X_000030"
     CDS             complement(33347..34390)
                     /locus_tag="ACG84X_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9125942.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(34393..35061)
                     /locus_tag="ACG84X_000031"
     CDS             complement(34393..35061)
                     /locus_tag="ACG84X_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9125943.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERVGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            35203..37539
                     /locus_tag="ACG84X_000032"
     CDS             35203..37539
                     /locus_tag="ACG84X_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFP9125944.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(37654..37965)
                     /locus_tag="ACG84X_000033"
     CDS             complement(37654..37965)
                     /locus_tag="ACG84X_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9125945.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            38146..39621
                     /locus_tag="ACG84X_000034"
     CDS             38146..39621
                     /locus_tag="ACG84X_000034"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFP9125946.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            39668..40252
                     /locus_tag="ACG84X_000035"
     CDS             39668..40252
                     /locus_tag="ACG84X_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFP9125947.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            40254..40673
                     /locus_tag="ACG84X_000036"
     CDS             40254..40673
                     /locus_tag="ACG84X_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFP9125948.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(40954..41238)
                     /locus_tag="ACG84X_000037"
     CDS             complement(40954..41238)
                     /locus_tag="ACG84X_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFP9125949.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(41590..42300)
                     /locus_tag="ACG84X_000038"
     CDS             complement(41590..42300)
                     /locus_tag="ACG84X_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFP9125950.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(42297..43769)
                     /locus_tag="ACG84X_000039"
     CDS             complement(42297..43769)
                     /locus_tag="ACG84X_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFP9125951.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            43907..44380
                     /locus_tag="ACG84X_000040"
     CDS             43907..44380
                     /locus_tag="ACG84X_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFP9125952.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(44533..45084)
                     /locus_tag="ACG84X_000041"
     CDS             complement(44533..45084)
                     /locus_tag="ACG84X_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFP9125953.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            45189..45719
                     /locus_tag="ACG84X_000042"
     CDS             45189..45719
                     /locus_tag="ACG84X_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFP9125954.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(46202..46645)
                     /locus_tag="ACG84X_000043"
     CDS             complement(46202..46645)
                     /locus_tag="ACG84X_000043"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9125955.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(46661..47821)
                     /locus_tag="ACG84X_000044"
     CDS             complement(46661..47821)
                     /locus_tag="ACG84X_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9125956.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            48328..50028
                     /locus_tag="ACG84X_000045"
     CDS             48328..50028
                     /locus_tag="ACG84X_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9125957.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(50130..50963)
                     /locus_tag="ACG84X_000046"
     CDS             complement(50130..50963)
                     /locus_tag="ACG84X_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFP9125958.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(51267..53432)
                     /locus_tag="ACG84X_000047"
     CDS             complement(51267..53432)
                     /locus_tag="ACG84X_000047"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFP9125959.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            53692..55986
                     /locus_tag="ACG84X_000048"
     CDS             53692..55986
                     /locus_tag="ACG84X_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFP9125960.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            55979..56644
                     /gene="pgmB"
                     /locus_tag="ACG84X_000049"
     CDS             55979..56644
                     /gene="pgmB"
                     /locus_tag="ACG84X_000049"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFP9125961.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            56637..57644
                     /locus_tag="ACG84X_000050"
     CDS             56637..57644
                     /locus_tag="ACG84X_000050"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFP9125962.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            57666..58685
                     /locus_tag="ACG84X_000051"
     CDS             57666..58685
                     /locus_tag="ACG84X_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9125963.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(58966..60333)
                     /gene="nhaC"
                     /locus_tag="ACG84X_000052"
     CDS             complement(58966..60333)
                     /gene="nhaC"
                     /locus_tag="ACG84X_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFP9125964.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(60442..61863)
                     /gene="tyrP"
                     /locus_tag="ACG84X_000053"
     CDS             complement(60442..61863)
                     /gene="tyrP"
                     /locus_tag="ACG84X_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFP9125965.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(62106..63983)
                     /gene="tdc"
                     /locus_tag="ACG84X_000054"
     CDS             complement(62106..63983)
                     /gene="tdc"
                     /locus_tag="ACG84X_000054"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFP9125966.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(64274..65530)
                     /gene="tyrS"
                     /locus_tag="ACG84X_000055"
     CDS             complement(64274..65530)
                     /gene="tyrS"
                     /locus_tag="ACG84X_000055"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFP9125967.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(65642..65847)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            66110..67411
                     /locus_tag="ACG84X_000056"
     CDS             66110..67411
                     /locus_tag="ACG84X_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFP9125968.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(67480..68079)
                     /locus_tag="ACG84X_000057"
     CDS             complement(67480..68079)
                     /locus_tag="ACG84X_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9125969.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            68333..69214
                     /locus_tag="ACG84X_000058"
     CDS             68333..69214
                     /locus_tag="ACG84X_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFP9125970.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            69227..70837
                     /locus_tag="ACG84X_000059"
     CDS             69227..70837
                     /locus_tag="ACG84X_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9125971.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(70914..71573)
                     /locus_tag="ACG84X_000060"
     CDS             complement(70914..71573)
                     /locus_tag="ACG84X_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFP9125972.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(71856..72521)
                     /locus_tag="ACG84X_000061"
     CDS             complement(71856..72521)
                     /locus_tag="ACG84X_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFP9125973.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(72668..73273)
                     /gene="dhaL"
                     /locus_tag="ACG84X_000062"
     CDS             complement(72668..73273)
                     /gene="dhaL"
                     /locus_tag="ACG84X_000062"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFP9125974.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(73301..74311)
                     /gene="dhaK"
                     /locus_tag="ACG84X_000063"
     CDS             complement(73301..74311)
                     /gene="dhaK"
                     /locus_tag="ACG84X_000063"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFP9125975.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(74286..74681)
                     /gene="dhaM"
                     /locus_tag="ACG84X_000064"
     CDS             complement(74286..74681)
                     /gene="dhaM"
                     /locus_tag="ACG84X_000064"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFP9125976.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            74835..75155
                     /locus_tag="ACG84X_000065"
     CDS             74835..75155
                     /locus_tag="ACG84X_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFP9125977.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(75267..76124)
                     /locus_tag="ACG84X_000066"
     CDS             complement(75267..76124)
                     /locus_tag="ACG84X_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFP9125978.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(76232..77536)
                     /locus_tag="ACG84X_000067"
     CDS             complement(76232..77536)
                     /locus_tag="ACG84X_000067"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9125979.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(77533..78042)
                     /locus_tag="ACG84X_000068"
     CDS             complement(77533..78042)
                     /locus_tag="ACG84X_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9125980.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(78217..80352)
                     /locus_tag="ACG84X_000069"
     CDS             complement(78217..80352)
                     /locus_tag="ACG84X_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFP9125981.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(80435..82090)
                     /locus_tag="ACG84X_000070"
     CDS             complement(80435..82090)
                     /locus_tag="ACG84X_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9125982.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(82092..82406)
                     /locus_tag="ACG84X_000071"
     CDS             complement(82092..82406)
                     /locus_tag="ACG84X_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFP9125983.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            82576..82836
                     /locus_tag="ACG84X_000072"
     CDS             82576..82836
                     /locus_tag="ACG84X_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFP9125984.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            82850..83164
                     /locus_tag="ACG84X_000073"
     CDS             82850..83164
                     /locus_tag="ACG84X_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFP9125985.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(83894..84448)
                     /locus_tag="ACG84X_000074"
     CDS             complement(83894..84448)
                     /locus_tag="ACG84X_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFP9125986.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(84574..86503)
                     /locus_tag="ACG84X_000075"
                     /pseudo
     CDS             complement(84574..86503)
                     /locus_tag="ACG84X_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(86809..87525)
                     /locus_tag="ACG84X_000076"
     CDS             complement(86809..87525)
                     /locus_tag="ACG84X_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFP9125987.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(87526..89349)
                     /gene="glpO"
                     /locus_tag="ACG84X_000077"
     CDS             complement(87526..89349)
                     /gene="glpO"
                     /locus_tag="ACG84X_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFP9125988.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(89363..90859)
                     /gene="glpK"
                     /locus_tag="ACG84X_000078"
     CDS             complement(89363..90859)
                     /gene="glpK"
                     /locus_tag="ACG84X_000078"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFP9125989.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(90995..92455)
                     /locus_tag="ACG84X_000079"
     CDS             complement(90995..92455)
                     /locus_tag="ACG84X_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9125990.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(92445..93740)
                     /locus_tag="ACG84X_000080"
     CDS             complement(92445..93740)
                     /locus_tag="ACG84X_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9125991.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(94072..94749)
                     /locus_tag="ACG84X_000081"
     CDS             complement(94072..94749)
                     /locus_tag="ACG84X_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFP9125992.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(94779..95870)
                     /locus_tag="ACG84X_000082"
     CDS             complement(94779..95870)
                     /locus_tag="ACG84X_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFP9125993.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(95971..96405)
                     /locus_tag="ACG84X_000083"
     CDS             complement(95971..96405)
                     /locus_tag="ACG84X_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFP9125994.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(96989..98446)
                     /locus_tag="ACG84X_000084"
     CDS             complement(96989..98446)
                     /locus_tag="ACG84X_000084"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9125995.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(98443..100338)
                     /locus_tag="ACG84X_000085"
     CDS             complement(98443..100338)
                     /locus_tag="ACG84X_000085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFP9125996.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(100396..102171)
                     /locus_tag="ACG84X_000086"
     CDS             complement(100396..102171)
                     /locus_tag="ACG84X_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFP9125997.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(102221..103717)
                     /locus_tag="ACG84X_000087"
     CDS             complement(102221..103717)
                     /locus_tag="ACG84X_000087"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9125998.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(103911..105533)
                     /locus_tag="ACG84X_000088"
     CDS             complement(103911..105533)
                     /locus_tag="ACG84X_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFP9125999.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(105861..107174)
                     /locus_tag="ACG84X_000089"
     CDS             complement(105861..107174)
                     /locus_tag="ACG84X_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFP9126000.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(107419..107643)
                     /locus_tag="ACG84X_000090"
     CDS             complement(107419..107643)
                     /locus_tag="ACG84X_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126001.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(107663..108085)
                     /locus_tag="ACG84X_000091"
     CDS             complement(107663..108085)
                     /locus_tag="ACG84X_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9126002.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(108227..108937)
                     /locus_tag="ACG84X_000092"
     CDS             complement(108227..108937)
                     /locus_tag="ACG84X_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFP9126003.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(108955..109452)
                     /locus_tag="ACG84X_000093"
     CDS             complement(108955..109452)
                     /locus_tag="ACG84X_000093"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9126004.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(109489..109941)
                     /locus_tag="ACG84X_000094"
     CDS             complement(109489..109941)
                     /locus_tag="ACG84X_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9126005.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(110076..110681)
                     /locus_tag="ACG84X_000095"
     CDS             complement(110076..110681)
                     /locus_tag="ACG84X_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFP9126006.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(111131..111751)
                     /locus_tag="ACG84X_000096"
     CDS             complement(111131..111751)
                     /locus_tag="ACG84X_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9126007.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(111753..112622)
                     /locus_tag="ACG84X_000097"
     CDS             complement(111753..112622)
                     /locus_tag="ACG84X_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFP9126008.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(112645..113052)
                     /locus_tag="ACG84X_000098"
     CDS             complement(112645..113052)
                     /locus_tag="ACG84X_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFP9126009.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(113071..114360)
                     /locus_tag="ACG84X_000099"
     CDS             complement(113071..114360)
                     /locus_tag="ACG84X_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9126010.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        33430 a        23669 c        20032 g        37230 t
ORIGIN      
        1 tcattttcaa aataaataag ggaggtgtga caaaattctt gtcacacctc ccttttccga
       61 ataaactgtg ttccagaaat agcttcttcg aaaataagct gaaatttcac aaaaatttga
      121 gaagcaattt tcgtacattc cttcttcttt cttgaaactg accacttctg tcacaccctc
      181 tcttctatca ctttcctttt ttcacacgac tcccggtttc tttgataaat ctcgatactt
      241 tcaattttct tgaatttttc atttgaggta cacatagata cagacgattt cttgctctag
      301 tcatcgcaac ataaaatagt cttcgttctt cttctatcgt cgttactggt tctgctttta
      361 tttcattaaa gtcgattact ttcttttctg tcgctccgtt ataaggcaaa cttccttcgt
      421 tacaaccaat caaaaagaca tttcggtaac taagaccttt acttttgtga atgctctgga
      481 tacatagtgc atcaagtttt ccttgtctgt aagcaatcaa gcgggttttt aattctttag
      541 ctgtcgcttg ggtttcttgc gataaggctt ggagtcttct gaaagtagca tgctgcttta
      601 cttcttctcg tatccattct tgatcactct ggtcgatttc cttagctata cgtggcagat
      661 gaagatagct ttgaacaagc gaatagattt cttgatgctg gtctgtttta cgcaacgctt
      721 cctcaaactc tcggatttct gcagatttcg attttaaatt ggggcttatc gacaaaatat
      781 aatctgcaac ggctatattt tgatatttag gagaaaagta ttgatcgcat tcactttttt
      841 tcaggtagca gtctgccatc agctgccgga gcaattgctg gtaggcctga tttttctttt
      901 gcagattcag tgctgtttgc caatgaacaa ttttttgata gaaatgttgg aaagacttga
      961 taccaaagat accttcatat ggactatctg cttccagtac aaaaggaata ttcgttttca
     1021 gcagagattg gacaagctgc tgcgtttgtg aagctgatcg gtataatatg attgattcct
     1081 tatatttccc atttttttga ataaatgtct gaatttgttt gattagccac tgactttctg
     1141 ctttagtatc agaaaacaaa taggcttcca taacacctgc ttctttttgt gctggaatca
     1201 tcgcctttgg tatccgatca tttttattat agctgatcaa tctatttgct ccttggacaa
     1261 tagctgcccg agaacgataa ttagttaata agaaaagagt tttggtagga tattcttttt
     1321 caaagttctt gatgtatgct ggctctgatc ctctgaatcc atagatactc tgatcatcat
     1381 ctccaacaac aatcaacttg atcctgtttt cctttgtcat ccgtttcacg atttcccatt
     1441 gaagtggatt agtatcttga aattcatcaa tgaatagata atcatatttt tggccgatat
     1501 aatgctggat ctcctcattc tccaaagcgc ttttcagatt ttggagtaca tcattgaact
     1561 ctagcaattg ctggcttctt ttttgttctt ggagttccgt gagcaatcca tacagtcgtt
     1621 ctgatatcgg ctgtcgtgca ttcttatcaa tggaatcata tttttcttta actaactgaa
     1681 ccatttcttc tactgaaagg ttcatattct gccaatagtc taaccgagaa gcaatcgttt
     1741 tttctccata ttgatcaaat atataaagat tatatttacg tatcagctgt tgcaaaacag
     1801 cattcacttt ttgtgcagta tcctttgaaa agtctccttg tattccttgc attgctactt
     1861 caggaaattt tcgacaaatt tcattgtata tcctaaaaaa gatactatgg aatgttccga
     1921 tatggacagc ggtttttctc tggctgaaat tatctactcg tttttttagt tcatttgcag
     1981 cgttccttgt aaaagtgatc attagtatgc gttcttcgtc tacttgtttt tgcgtcatca
     2041 gataaacagc ttttgcacag attgtttgcg ttttgccgct cccagctcct gctatgattc
     2101 gaagatgttt cttcatatca tatgtgatag ctgctttttg ttcttgattg aagcgattat
     2161 aggaacgttt ctccatcatt ttaaagaaag agctgtttcc ttcactttct tttacttgta
     2221 cttcttcctc aataagtccg ggtgcttcgc cataagccgc ttcataggta gcaatgattt
     2281 cttcttgtag ccgaaagact tgttgaagct ttttatactt gttctcccag cgtttcaatt
     2341 ctttttgtaa tcggagaatt tctttttcat tcaactgatt gatttccttc ccatctttct
     2401 tctttgaatt tgtttatttc aagttggtta tttaaagttt cgttgtctat tttttcttta
     2461 tactaacaga cctttctaaa aatgaaaatg ggaagcgata tgattttagt tttctgaaaa
     2521 tttttccttt ttttcaatcg tttatgctaa gataaggaag acaaaaatat tcataaaagg
     2581 tgatgaaaaa aatgcagact tcctttcacg aggggcgtac aataggactt ttgctgacat
     2641 ttatcggagg agccatggac agttatactt atatccaata tggtgctttt gcctctgctc
     2701 aaactggcaa tatcattcta tcgatcatcc aagcatttga cggagaatgg ctaagtgttg
     2761 gtaaaaaagt attgtctacc cttttctttt tcttagggat tcttctaaca aagtatctaa
     2821 ttgattattt tagaaaaaaa gaaaaacatt tctggcgctt gtttgttcta tattatgaag
     2881 cagtgatttt tttctttgtt agtttgacac ccgtccatga gcatcccgca ttagtaacga
     2941 ttttgattgc ttttactgca tcgatccagt gggtagcttt tgataaaatc aacgggcgtg
     3001 cctacactaa tttatttaca actggaaatt taaaaggggt agcaacgaac ttatatgatt
     3061 attgtatttc taaagaaaaa gcagattttg atcgattttt ccactatcta agtgtcgttc
     3121 ttgcctttat cgcaggagct attgtccttg ttttctgtca tcatctgttt ggcgcccatt
     3181 cgattttgat cgtttccatt ttatttttga tcatggccct cactcagaca tttcatttat
     3241 ggcaatttta tcatacgaat cggttcacta tttgatctca atgaatcaaa aaaactaagc
     3301 aagatgctgc tcacagagaa atatctgcga gtgagcaatt tgcttagttt ttatattatt
     3361 tagttgtaaa gattcccttt gctttcgggt tatttgtagt gtagcggatc gactgggcat
     3421 ctgcctcttc tgtcattttc tttgcccgca tcttgatttc ttgtacgatt tgttctccac
     3481 atgccggatc ggctacgaaa tcatatttgt ccccatcgat cactattttg ggacatatat
     3541 caaactgttc ataccactct tcgtatcgtc gattgagttc tttatagtag gaatagagtt
     3601 caggatcttg ttctagctgt tcatattccc ggcctctttt tttgattctc gctaacatag
     3661 tttcaaagga tacacgaata taaaccagta gatctggttt cttttgtggc gaaatttctt
     3721 ctaactcctt cagcatcgtt tctaaaagac cttcatactg ctttacttct acttcagaaa
     3781 cacgccctaa atctgcattc aaatgaaaca gcatactatc ttcgtagatg gagcggtcta
     3841 gtacgttgtc atcatggctg aaagcatctt tgattgccaa aaagcgtttg ttcaaaaaga
     3901 aaatctgtaa taaaaaagta tacttttctg gattagaata aaatagcggc aatacttcat
     3961 tatcttccac gttctcataa aaaggttttg tttctaaatc ttgggcaagc atttcagtta
     4021 gtgtgctttt ccctgcaccg atcgttcctg caacaatgat cacaattatc ggcatccttc
     4081 ctgtaataaa atctgttctt cattttacta cttcatttat agaaataaaa gccttgactt
     4141 tatctgctcc ttaaaagcta cttctctaaa agtagccaaa agtaactcct attcatgaaa
     4201 ataaaggctg tgacaaaagt cttgtcgcag cccttttttc aaataaacag tattctcctg
     4261 ccaacacctc ggtcacaagg caatattcat aaaacatgaa aagctgtttt ttaacattat
     4321 tccttgtaac tcagagctaa acgggagact cacaacctct ttatgctctc aacattttat
     4381 ctgtttttat tcttctattg tacttgattt gcgtacaact aactgccagt gcagattatg
     4441 agcggtatca ttgtcttcta ctgcgcattt catgacacgt atcatcacac tattttcata
     4501 gattttttct atttttcctt ttattggtga ttcaaataaa tcagatttaa atgcatatgt
     4561 ttcgccgact tcaaacaatt gttcattttc cataagaatc cctccatcac cttttataag
     4621 gtcagtaatt ttttaacata aatcactcga aaaagcacaa acttgtcata aaaagtactt
     4681 ttcgtatcaa aactgtcact ttttttggta aggttcttgg aaaacgaaga tttttttagg
     4741 agatcatgac ggttttgatg tcaaaaccac tttttatgaa acaaaagacg ttttttattt
     4801 tttttagcat aaaatttgtg gtggaggtac gtatgagatg aaagataaag ttgtgaacaa
     4861 attattagaa gccttattca gcggagacaa atcggaagaa gatatggtgt atgtccaagt
     4921 aaaatttgtc ttagaagttt tattgaataa tcttggaaaa ctagcggtcg ttctagtctt
     4981 ttctctggtg acaggctcat gggcggaaac aggaatcacc tttctttctt atatctgcat
     5041 ccgcagatat gcttatggat tgcattccga ctctgaattc gtttgtctgc tgtggacact
     5101 actttattta tggggcgttc ccttggtgat gaaacatctg caattgacta tctccttccc
     5161 aatgatggtc tttttgttaa tcagctgctt tttgttactg cttcgctatg gatcaagagg
     5221 tacagcaatc aatcccattg aacccgagaa acgtccccca ttattaaaga aggcgatcag
     5281 catgtttcta attttttctc tcattacgtt atttttctca gcttcttact tttctaccta
     5341 tttgctactt gggattgttt tagaaatagc tacgttgctt cctattacaa actacttgat
     5401 gaattttgga ggaatctttc atgaaaaaaa caatcattaa acaattaact aacttatctg
     5461 acttttttgt atctggctgc tgctttggta tgagttctga attcaaaatc cctgaaaaat
     5521 taaaaaaata atacgccaat tgtgctataa tttggtaaaa atcaatggga gctgtacttt
     5581 atgtttttat ggtccatagc gttgcaatat ttgatttaca caatttgtat cttattgatt
     5641 gaccatcaca tccgatacaa atatctgttt gcgggagtca ttctgatttc ttgtattttg
     5701 attggatggg tctattcgat tttagggatt tttactgctc taattgctat aggaatgctg
     5761 atgcttactt ttttcttctt ttcgacttcg cgtcaacaat tggtttacgc gcttcctttt
     5821 gggttattga cgtcgctttt aggagatcac ttaacaagca tcggcgattt ttttgttttg
     5881 aaatcttcgg ttattgaacc aggagattca ttgcagtatt ttcacattgt cttatccgct
     5941 tttttatctg ctttattagc tttttgttta aaaaaatcgt tagagacttg gtttcacact
     6001 gtggaccgcc gtatgatcgg tacgatcggg acattgatat tatttacata ctatatcatt
     6061 attttttata cccgtttttc tggtgaaaca cctgatgtct tagctttgaa tacgagtttt
     6121 ttcattctat atctgtgtgt tggcctgatc atcttggttt attattggaa aatctctaat
     6181 aagaaattag ctgatcagtt attagagcaa caagtcagga tgcaacagga ttatatcaaa
     6241 gatctagaaa aaaactatca agacttgaga gaattcaaac atgattacca aaatctgctt
     6301 ttttctcttc acagctatat ttcagaaggc gacttagaag gattacggtc ttattatgat
     6361 caaacgatat tacctacacg ccagatgatg aacctttttc cggccaatct aagtatgttg
     6421 gataatatga aagttcctga gatccgtagt ttactgtcat taaaactcat gatggcacag
     6481 gaaaaagggt tgatcgtcca gcttcatttt cctgagccaa tcgaactgga tacgaaacat
     6541 acggtaaacc ttgtacgtat gcttggtatt atcttggaca atgcgattga aggagctagt
     6601 gctgcaaaga agaaaaaaat cgaattgacc atactcaaga agaatcattc cgtgatgatt
     6661 cgtgtgatca atacaacaac aaatacatta ccgttaaacc agttgaaaca aaaagggttc
     6721 tcaacaaaaa caaatccaaa aaacgaaggc cttggcttgt ttatcttgga tgaattgaca
     6781 aagaccaatc cttatctttt ccttgaaaca tcaattgaaa accagcgttt ttctcaaacg
     6841 atttatatac aaataaaata aaggagtaat gatatgattc ccatttatat ttgtgaagac
     6901 gatccaaaac aattagaagt tttatcaacg gtgatcaaaa atagaatcat gattgaaaac
     6961 ttagacagtt atgtccatat ttctacctct gatccggaag aacttctcaa tgcagccaag
     7021 atcagaactt cttcttttgg tatttacttt ttagatatcg aactagaaga cagtgaaatg
     7081 gatggtgtag cgatcggtaa attgatccgt gaattagatc ctttaggaaa aataatctat
     7141 gtgacttccc atacggaaat gtcgatgaaa atcttaaaaa gcaacatcga accgactgat
     7201 tatatcgtca aagaagatct ttatgattta aaagaaaatg tcgagcatat cctgagcaaa
     7261 attttcgaag attttcaaat gtcccaaatc caaaaagata tcttcaaaat agagtttaat
     7321 gatgagatca aatttttacc gatcaaagac atccaatatt tttctacttc gctaggagcg
     7381 ccacataaac tggaagtcca tttgactcat gcccaattac aattctatga gaagatcaaa
     7441 gaaatcgaga aaatgcatcg gaattttatc cgttgtcata aatcctatgt tatcaataca
     7501 caaaatgtgc ggtcgattaa taaaaaaacc agagaagtca cgttggcaaa cggcgagacc
     7561 atcccagcct ctatccgtgg attaaagaaa ttgatttcat aaaaagaacc gaatagtttg
     7621 gaccgactaa atgaccagcc gatccaaacc cttcggttct tttttgccta tcagtgcaaa
     7681 agcatttcct gtgcaatttc acgtccatcc attgtatctg gataaaatgt tggccaattc
     7741 tccatttctt tcagcaatac ttcttgactt tcatttcctg catataaatg aaaatgttcg
     7801 gagtcagccg gtgcaatcgt gtgatcactg aattgaatat atctaaaagc gccactttcc
     7861 ttatcttctg cttcgaatag ataccttacg ccacggtttc ctgcctcgta ggtcaagatt
     7921 tctttcccta cataacgata atttgaacgt ttcgttgttc cattcttaaa cgtaaatgcc
     7981 atctctttct cactgatctt gattgaagca atatctgttt gatagccctt cgtataatat
     8041 tctttatatt cttgtgctgt cttatcctga ttcaattttt ctttatattc aaaaacagga
     8101 tcaaaagtcc catcttctac atacgtatct actgtttgcc aagttcctgc ccaatctgaa
     8161 agagagcgat cttgtacatc ctcgtcttca aaataaccgt tgtagacgct cttttctttt
     8221 ttgggggtca aagtatcttc tagcgggttt tctgtctctg tcgttttttt caacgcttcg
     8281 aggtttgctt ccatgataga aagatagttt tctccatttt ctatttgttc attcgtcaat
     8341 ccttccaaag gattcaatac ttctaaagat acacctgctt cgtttgctaa cgttctggca
     8401 atactatctt tggcgttttc ttcaaaataa atatagttga ttccatgttc tttaacaaag
     8461 tgtttcagtt cagcaattct cgccgcagac ggttcttcac tagaagaaag accagcaatc
     8521 gatacttgat tcaatccata ttctaacgct agatagttga atgcagcatg ttgcgtgaca
     8581 aaagatcttt gttttgcttg cttaaaggtt tcttgataaa gctgatggag tgcttgaagt
     8641 ttctcggtat aggctgctgc attttttgtc catacttcct gtttttctgg gtaagcttca
     8701 atcagctgat cacgtatgtt tgctacctgc ttgattgcta aacttggagc tagccataca
     8761 tgtgggtcta gctcatgtgt atggccttct tccccgtgtt catggtcatg atcatgtcct
     8821 tcttcacttc ccggaagtaa aagcatacct tctgtcgctt ttatcgtatg gacattgcct
     8881 tcttgtaatg ttttttggat tgcggggacc catgtttcca tgttttcatc attataaaca
     8941 aagatatctg tatcttggat ctttgccatg tctttagcag aaggttcata atcgtgggaa
     9001 tcagtccctg ctggaatcaa taactctact tctccttcat ccccgacgat tgcttttgta
     9061 aaatcataca tgggataaaa ggtcgtcatc acgctcaatt tttctttact gtcctcggct
     9121 ttcccacttg ccccgcaagc agttaacata cctgctaaaa ccagcatggc caatatacct
     9181 atcaatcgtt tcatttatga cactcctctt ctcatcttct ttcatttgaa tgttccgatt
     9241 cgcttttcgc aaaccgtaat agttacgttt tagcaacagg atttaattta tcatatggtt
     9301 aaaagaactg tcaagcgttt tcttatttta attgatgaga aagtttatat gaatgattga
     9361 cgatattttt gcaatcaacc tctatcattt tccttttata cccgcttttg tctataatga
     9421 atttatagat aaaggaggaa aaagagtgaa aaaagaaaca gatacaacga atcgtttgat
     9481 ccgcttttta ggaggaaaaa cctcttacta tgttttagga atagttatct tacttgcgct
     9541 gatcatttat tttttccatc agatctcgtt tatattcaag cctgtcggaa tcattatcgc
     9601 tactatcttg cccccattat tgtttgcact gatcttgtat tatcttttgg aaccagtcat
     9661 caaacgtttg agcaagcacc tttcgaggaa cttgtcagtc attatcgttt atgtgattat
     9721 tttattttta ttggggcttg gaagcatatg gcttattcct tttcttgaag aacaggcaaa
     9781 gacattgatc agtagtttgc cagatttgtt tcaagatttt caagagagtc tccgacaatt
     9841 tttggagaaa acaccttttg ccgattcatt taatcaattt ttcgcttcta ttgacgacgt
     9901 gacgtctgat atagctggat ttattggaaa ttattgggaa agtggcgcac aacggatcag
     9961 caacattttt tcaactgtta cagctatttt tattacttta tttactggtc caattgtcgc
    10021 ttttttcctt ttgagagatc ctcaaaaatt ttatcagtca gttttagcga ttgtcccacc
    10081 agcatttcgt acagatttta aaaatttgac aaagattgct aatcaacaat tgggttcatt
    10141 tctaaagggg caaatcattg cttcatttat ccttggagca gtctactggg tttgtttctt
    10201 actgatcgga ttagaatttg ctagtgtttt agctatttct gctgggttgt tatgtatcat
    10261 tccatatatt gggccgttta tcgccttctt tccaggtttg atcattgcat tccaagactc
    10321 tacttttatg gctgtcaaat ttgtcattgt ctggtttgcc gtacaacttc tccacggtga
    10381 cttggtgatt cctcgagtaa tgggtgatcg tttacagatc catccgatta cgatcttaat
    10441 cgttttactt gtcatgggtg atctaatggg aattgtgggc gttatttttg gtattcctat
    10501 ctatacgtta gtcaaattac tcgttacttt tattttccgt aaattcaaac aacgctacaa
    10561 taaattttat ggcgataaag gagagtatga aaactcttca ttttctgaag aagattattt
    10621 taaataaaac acaaaacgtc gatcttacga gaatagctcg taggaacgac gttttgtgtt
    10681 tttgttttaa tttttcagca aagcaattgc ctggtatggt tttagctcca gactttgatg
    10741 aagaacagta tcggaataat tatcgataag aatattggct tctgtgaatc cttctgggat
    10801 ggcgatcctt gtatctttat catagaaatt tgttaataca agcagctgct gtccttcaaa
    10861 ttggcgaaga aagccataaa cttccggatg atttgcttca taagcatgat aatctccttg
    10921 tgcaacgatt ggatatgttt ttctcagccg aatcaatttc ttgtaatagg acaaaataga
    10981 atcttcagaa gatagttctt tttctacatt aatctcttct agcttgcctc caacttttaa
    11041 ccaaggtttc cctgtagtaa atcctgcttg ttctgtgtct gaccattgca tgggtgttcg
    11101 agagttatcg cgagattttg ctttgatccg acgaaacgct tctttttctg tgaatccttg
    11161 ttcaaggagt aacttataag cattcaaact ttctacgtca atatagtcgg aaatcgatga
    11221 atagtctggg tcgatcatgc cgatttcttc tcccatataa atatagggcg tcccacggtt
    11281 caaatggatc atggttgcta gcatctctgc tccttgtttt cgatactgat cgatagctac
    11341 aaatcgattg agcgcacgtg gctgatcatg attattaaaa aatagagcat tccagccgtt
    11401 accctcactc atcttttctc cccatgtatg aaatagtcgc tttaattctg caaaatcaaa
    11461 tggaggagta gaccatttat tcccattttc ataatcgact ttcaaatgat ggaaattaaa
    11521 gaccattgat aattcttctc tactaggttc tgtatacaag atacaatttt cgatcgtcgt
    11581 agagctcatt tcaccgactg tgatgatagt ggaatccgtc ccaaacgttg cttggttcaa
    11641 ttcttttaga tacgtatggg tgattggttt gtccgtatat tcaggtttgc catcattttc
    11701 tttattattt ttcaattgtt cgtctttacc gataacattg ataacatcga aacggaatcc
    11761 ttttacccct ttttccatcc aaaaacgaac aactttgaat agttcctctc ttactgcttg
    11821 gttccgccag ttcaagtcag cttgtgtccg atcatataag tgcaaataat atttccccgt
    11881 atctccaaat ggcgaccaag cacttccacc aaattttgat acccaatccg ttggctcttc
    11941 tcttaaaatg aagaagtcct gataatgctg gtcccctgct agtgcttttt tgaaccattc
    12001 atgttctgtc gaaacgtgat tcagcaccat atcgagcatg atttctatcc ggtatttctt
    12061 tgcttcggct attagctgtt cgaattcctc catcgtacca aagataggat cgatggctgt
    12121 gtaatcagag atatcataac cgttgtcttt ttgagggctt ggataaatag ggtttagcca
    12181 aatcatgtcg atgcctagat cattcagata cgggagtttt tctttgattc cttttaaatc
    12241 tccaattcca tcaccattac tgtctttgta agatttggga tagatttggt aaatgacttt
    12301 gtctttaaat gtcatggata tttacctcca ttcaactgat ttattaccta ccacaactta
    12361 tatatacaag ttatcattta ttattataac tgaaccgaaa gcgtttgtaa aatttatctt
    12421 tatacattct aagaggtctg ttgcccaata aaaaacaaga gatcagacat gtatttgtct
    12481 atcctcttgt ttaaaatagc aaaatattct tgtttcttct ataaatggtg ttcaaaagct
    12541 tttatctacg gcaatcagtc ttctcaaatg taaaacatga ggagctaatt ttatttgagt
    12601 attctttttg ctcgatgcag gacggctttt ttacaacctc tgattcatgg tgttcaatca
    12661 gctgtccttc ggtattagct caaaaaacgg caaaatatga aaaactattt tgccgtttgt
    12721 ttctctaata ctcaggtcaa accgctgatt tcacaacctc tgtttttatt cattcgattt
    12781 caacgcatca atcatatcga tatgctttaa tttgaaatgg gtaacaatca tcacaataac
    12841 cgtaaatacg atagttaatc ctgctgataa gacataagcc caccatgtga tcactaatgg
    12901 aaagatgaca ttctccatag acgcttgttg caagatgaag tcagtcaata tatatcctac
    12961 accaaatcct ccgatgattc ctaaaagagt aaagatgata ttttctcgaa caatgtacat
    13021 cgtgacttct ttatcaaaaa atccaaggac ttttattgta gataattcgc gtacacgctc
    13081 ggaaatattg atattagtta gattatacaa gacgataaaa gccagcagtc ctgataatac
    13141 gacaaagatt aagacaaccg agtctaagtt cgccattgat tcttcttgcg tttcgatttg
    13201 tttggacatg aaagacgtat ttgtcacagc gtctgtggca agcagtttct cggaaagcat
    13261 ttcttcttct tttgttgtca tcttatctgt acgcagcaaa aatgcattat ccatcatcga
    13321 ttgatcagta actgaagcat aatattcagg ggacatataa ataaagctac ctagatagtt
    13381 tttcacgatt tcttttactt cgactttcca ttctttttga tcttcatcat aaagcgaaat
    13441 atgatctcct gtagataagt caaatagttc tgctactttt tgcgtaatag cgattcctgt
    13501 tttaggcaag gagcgtgggt tctcttcaag atcagttaaa tggataaaac gatccaaatc
    13561 agctgtttta cttggtacga tcactgtcag actttgcgaa gcatgtcctt tttttctcaa
    13621 ttctacggtt tgagtatgaa tagctaggat ctcatttact ttttcttgct tctgcagcat
    13681 atccgctgct ttttgacgac tatcttccgt ggatgaatcc aatgtaacga ttgcttgata
    13741 gtcaatgatc ggtccaaatt gtttggctga aacagaactt agagaatctt tcaatcccac
    13801 gcctgcaacc atcagcccgg cacatccagc aattccgata atcgccataa gcattcttga
    13861 cttatatcgg aagagatttc ggtaactgat tttttgatta aagctaaggc gtgaccacag
    13921 cggagtgatg tattcaagaa aaatgcgttt ccctggcttc ggtgctttcg gttgaagcaa
    13981 tgcagcaggc cgttctctta aatctttgaa taaaacgatc attgcagcgc caaatgcggc
    14041 aatgaagaat gcggcagctg cttgtaaaat cggcggccag tcataaaaaa taagcgcact
    14101 cccaatatca taccgctcgt tagacagctc aaaaatgatc cttggcaaaa gattcgttcc
    14161 taatatcgtt cctaaaacaa tacctatccc tgaggctaga cttgcataga ttgcatattt
    14221 ttttgcgatt tcaactttcg tataacctaa cgcctttaat gtcccgattt ccctgcggtt
    14281 ttcttctacc atacgtgtca ttgtcgtaaa ggtgatcaat gcggcaataa agaaaaagaa
    14341 aacaggaaaa acattggcaa tcgcagcgat acgatcagac agatcaccaa attcttgaaa
    14401 accgacattt tctgaacgtt cattgtatag gtatgatggt ttagttaaat tttcaatttt
    14461 ttctgcattt cgattcaatt cttcctctgc agaggccagt tcacgttctt tctcaactaa
    14521 ttgcctttct tgttcagcaa gttgagcttc ttgttgagat aatgtttgaa cagcgattgt
    14581 tcgttgcgct tcaggaagct gctggatagt tgctgactgt tgcgctaact gttttttagc
    14641 atcttctaac cgtgttcttg cttgcgttgt ttgtgctttg ccatccgcta ttttttgctg
    14701 tgccggttct aattcttcgt tggccgattt tttcagctct tctaagcgtt cttcgggtcg
    14761 atcttgtaaa tacttttctg ccttttcttg attttgctcc attttatctt tgtaagcttt
    14821 gctgtacgta ttcaaattct ttacgtttgt aaaatcaaga tataagacag aataaatatc
    14881 tgttttaaaa acggattcag gtaaatagac aaaataatcg acgctaccat ttccgacgtt
    14941 cgcgtatcct ctctccaaat tgttgatgaa caatggagaa cggacaaagc ccgtgatggt
    15001 atactctttt tctttcaatt catctgaatc aatctgataa atatcaccga ttttataccc
    15061 ttcatcttcc gctttttcat ccaatacaag ctggtttggt ttttccggga gttttccatc
    15121 agttaattgt agcttgttct gcttgttatt tttgttataa gaaaatattt gaatcacttc
    15181 gtttttgcca gtattggaat aatagatctg ttttcctgtt tctacttttg catctgggat
    15241 cttttctgct tgagcaatat ctttttgtgt caagccacca gtagaaacga tttgcaaatc
    15301 agaaagtcct gctgtaccaa catagtgatc catcgttttt tgcatgacag gtccagcagt
    15361 tttgacacct acaaataaaa gtgttcctag catgacaata aggatgattg caatgaatcg
    15421 tcctttagat tgccgaattt cgcgaaaacc tgctttaaga tatgttcttg ttttcataaa
    15481 atccccctac catacaatct catcaatgga tgaaggatga tcatttaatt caacagacct
    15541 tactttagca tcattaatgt gaatgactct atcagcgatg ggcgctaaag cagaattatg
    15601 tgtaatgatc aaaacggtat tgccgtgttg tctgctagcg ttttgcaata atttcaatac
    15661 ttgcttgccc gtttcaaaat ccagcgcgcc tgtcggttca tcacataaaa gaagtttggg
    15721 atttttagct agtgcacgag caattgaaac cctctgctgt tcgcctcctg ataattggga
    15781 cggaaagtta ttcaatcgat gagctaggcc cacttgcctc aatacctcta caggatcaag
    15841 cgcatcagga gaaacttccg ttgccaattc cacattttct tttgctgtta gattaggaac
    15901 gagattgtag aattggaaaa cgaaccctac atctgttcgt cggtaagcag taagctgttt
    15961 atctgaaaat tgcgcaatat ctgtgtcatc aataatgatc tgaccttcat caggtgtatc
    16021 catcccacct aaaatattaa gaatcgttga ctttcctgct ccacttggac caagtataat
    16081 cactaattcg cctttttcaa ttgaaaaaga aatatcgtca tttgctgtaa tggtcgtttc
    16141 tcccattttg tatcgtttgt attcattttt tacttcgaca tacttcactc tgattcctcc
    16201 attttcacga tatttctcgc tatatctatg catcgaatgc gttttctcac acttatttat
    16261 tttaccactg aatttctcta gactaaagaa aggaatcctt taatttagtt gacaaataaa
    16321 cgatttatga tttacttaca taaaaaacat tgttatttga aagaaggaac atcatgaatg
    16381 atttaaagga aaatatgatt tttgatttat caaaaactgc ttttgtcgcg atcgacatgc
    16441 aaaaagagat cgtaaataac ggtacactct ctccacacac tgcagcatct attctgacaa
    16501 acaatgattt gttagtaaga acattgaaac gtaccgctgc cttgaaagtt ttagtgaacg
    16561 tagacatctc cactttccct tatttgagtc aacaaactga tatgggtgga atgactgctt
    16621 ctgtacctcc agaattcact gatttacttt tgaaggattc tttgaaagat acagataata
    16681 tgttgactat cacaaaatac aatccaagtg ctttttttgg tacttctctt gatcttcaac
    16741 ttcgccggcg tggaatcgaa actatcattt taagcggtgt agcgacaaca aacggtgtat
    16801 atgctactgc attagatgcc tttcaacacg ggtaccatat cgtgcttgct gaagatgctt
    16861 gcagtgatcg tgacaaagaa tcccatcaat tgttcataaa aaagatattt ccgaaaactg
    16921 cacgagtacg ctcaacgaaa caaataatcg aagctatcca acaaagcaaa taagtactgg
    16981 cacacgtgat tttcatttac ttctttttga tttcatggga aaataaccac aggatttaga
    17041 taggagtatg aacatggtga aaaaaaagat cacaatcaaa gaagtcgcta aactttccgg
    17101 cgtttcaatc acaactgtct ccttgatatt aaatggaaat acggagaaat tcagtccgaa
    17161 aactgttcag aaagttttag ctgccaaaga agaattaggc tatcagcctg actattttgc
    17221 tagacaaatg attaccaagg aaacgaaaac aattggtgta ctcgttcctg atatcacgaa
    17281 tccattcttc agtacactga tgcgaggaat tgaggatatc ttgtataagc agaatttcgt
    17341 cacgatatta tgtaatgctg attctgatca tcaaaaagaa atcgaatatc tagccgagct
    17401 cacacgtcga ggtgtggatg gattcattat cgcgacttct gctgtctcta cagatgcaat
    17461 caacgaaaat ttgaaaaaac aaggccggcc cttcattgtt ttggatcaga aaaaatctga
    17521 aggatttagt gatgccgtac gaacagacga ttttcgcggt ggttacctag cgggcatgca
    17581 cttgcttagt ctaggacatc aaacgatcgc ccttgtctat cctgaaaatc caccggaaaa
    17641 tgtccacgct cggattgagg ggtttaaatc tgctcttgat gtttaccaaa tccctcacga
    17701 ccaactgatc ctcttaccta cacagttctc aaaacaaggt ggctaccaga tcacagcaga
    17761 acttcttgat tctgctgcaa ctggtgtgtt tgctttaaat gatgaattag cttttggatt
    17821 atatcgcgga ttagaggaag ctggaaaaag catccctgaa gactacagca ttattggcta
    17881 tgataatata gatatgtgcg agtatatcaa gccgaaactg acaacgatcg cacaaccaat
    17941 cttcgaattg ggacaaacat ctgccaagtt attgttagat cggatccaat tcccagaaaa
    18001 agaatgggaa gaaaaaagat tacctgtacg attagaaaaa agattttcaa ctgcaccctt
    18061 gaaatagctt tcaaggtgtg ctatattttt atcgaactat taaaacgttt tactaaaacg
    18121 ttttaaaaaa taattttccc atcaaaataa atgagatagt tggaggtttg taaaatgaac
    18181 acggttacag taattggaag tattaatatg gacactaccc ttcgtttaac caacatgccc
    18241 aagccaggcg aaacgatgca tgcgcatgag atttttcacg ctggcggagg taaaggtgcc
    18301 aaccaagcag tggcagccaa acgttcaggc gcacggacat cttttattgg aggcgttggg
    18361 gctgacagcg aaggacaaca gttattagat ctactgacaa aagaaaacat cgatacatct
    18421 gggatagctg aaatccaagg cgccacaacc ggacaagcaa tgattatggt agacgcagca
    18481 ggagaaaata gtatcttgat ccatgcaggg gcaaataatg ctttccatga acaagaagtc
    18541 ctaaaaaaca agcaactgat tacaaacagt gactttatta ttgctcagtt tgaaagtagc
    18601 ttagatgcga cgatcctagc tttttctatt gcaaaagacg caggaaaaac aacgatcctg
    18661 aatcctgcac cagctcgtga aacgattcct actgaactac ttgaaaagac agatatcatt
    18721 ataccaaatg aaacagaaac agaaatcatt acaggaatca gagtgacaga tcataacagt
    18781 ttggtcgcag cagccgaaaa actccatgaa ttaggtattg gaacagtaat cattacacta
    18841 ggcagtgccg gcgctttcta tcatacagaa aaagaacacg gtatcgtccc tgcttttaaa
    18901 gtggatgccg ttgacacaac agccgcaggt gatacattta ttggcgcatt aagcagcaca
    18961 cttcagccag accttagtaa cttgaaagaa gcgatccttt atggaaatct agcctcttct
    19021 gttgctgtgc agtcttatgg tgcgcaacct tctatccctt accgcgaagc tttagaacaa
    19081 tcagcagtct aaaattaaca atgagaggaa gaaacaaaca tgaaaaaagg aaaagtaatc
    19141 aattcagata tttcacgagt aatcgcacaa atggggcact ttgataaatt aagtatcggg
    19201 gatgcaggca tgcctgtccc ctttggtact gaaaaaatag atttggctgt ctcaaacggt
    19261 cttccaagtt ttttatctgt tttagaaaac gttttagaag aacttgaggt acaatcgatt
    19321 gaattggcgg aagaaataaa gacaatgaac ccggaaatat tggaaaaaat caaattattg
    19381 ttaccagata caccgattag ctttatccca catgaagaaa tgaaaaaaga gttgaataac
    19441 tgtcatgcat ttattcgtac aggcgaaatg acaccttacg ccaatattat attagtgagt
    19501 ggagtggtct tctaatggaa acgacaatga atcctgaaca gatggtactg tccgagcaga
    19561 ttcatatgct gattgaacag ttgggaggaa aagacaatat tgattctgtc cttccatgtg
    19621 cgactcggct tcgtatcaaa ttgaaaaaac agccagtagc caatgcagaa aaattaaaac
    19681 agcaaatccc ttccattaag tatttcattt tactcgatag atatgcagaa ataatcatgg
    19741 atcagggatt ggctcctgct tacaaggaat tgacgcgtca aatcgatcat tcagctccga
    19801 aagaaaagct aaatccgatc gaaaaactat ttggtttgat atcggaaatc tttacgccga
    19861 tcattccgct gtttgccggt tctggtatat taaaaggtct ggttgtttta gcgactacga
    19921 ttggctggct tagtgaaaca agcggaactt atcatatttt gtctgctgcg tcgaatgccg
    19981 tcttttattt tctgccaatc tttcttgctt tttctgctgc caaaacgttt aaagtgaatg
    20041 gatatattgc ggctgtcatt gctgcagcac tgattgaacc gaatctgacc tctttacttt
    20101 cagacagtgg caaagcagct actgattttc tggggattcc tgtagtactg atgcagtata
    20161 cgtctactgt catgccggcg attttaggta ttttctttta ttcttttgtt gaaaaattcc
    20221 tcaaaaaata tattcgcgaa aatatgcaat tagtatttgt acctttactt tcattagtta
    20281 tcacggttcc tttgacgtta atggtattcg ggcctgcggg tgtttacctt ggcgaaggtt
    20341 tagctgccgc aattacttgg atgatggata ttaacggacc gatcagtggc gcaatcatcg
    20401 ctggtggttg gaatattttg gtaatatttg gtatccaatg ggctgtaaac cctgtcatga
    20461 tcagtaatat ctctgcttat gggttcgacc gaatcgttcc gttgacagga gcagccaatt
    20521 ttggaatggc tggtgcagct ttaggtgtat ttctgcgaag taaacgttca aaaacccgtt
    20581 cgatctccgg ttctgctttt gcttcgattt tacttgcggg agtgaccgaa ccaactgttt
    20641 acggaattgc gatcccattg aaaaaaccat ttgttgctgc ttgcattggt gcagctgctg
    20701 gtggagctgt aatgggattt gcccaagtga aagcgatcgc ttttgtattt ggtagtctga
    20761 ccacattgcc tgcattcatt tccggtactt ttttctggta cttagcagga ctggctgtta
    20821 gtctagtcgt agcaatgatc actactctcg ttagcgggtt tgatgaagac ctaatgtctt
    20881 atgaatagtt aatgaaaaag actgaagtat gagatgttta tcacatattt cagtcttttt
    20941 ctttttagga tcattatttt tataaatttt tgtgatactt tccaaacttt ggtataattt
    21001 acatatgcat aaccattttt atccccactt gtttatcccc aaacaaaggt ggtctatgca
    21061 ataaaatgaa cgtcaaagaa aaacgaatga atgctcgttg cttatttaca aattgtttta
    21121 tttagaatac acagacagat ttatgaaaag aaaaagcttt tcgacacgat tatctgttcc
    21181 aaaaaatgtc taatgaatgc tgaataagac agaaaatcaa tgaaaggaaa aggactagtt
    21241 tattatgaaa aataaaaaaa cgatacgttt gctagctgct acttggctga ttgctccgtc
    21301 tgttttgtcg accaataccg tatttgccgt agataatcaa atagctgatc aaacagtcac
    21361 aacagatacg actacatcca gctcagctac tagtgaaaca acggattctt ttacagaaga
    21421 cccaactgga acaactaact caacaacagg atcgaccgag ccaactgaaa ttgatccggc
    21481 tgatccatca gaaaatgaaa agccagccga gacatattcc cttacaattg ctccttcttt
    21541 gattggtaag atccaactga ctgcttcgac agcggattcc cctgaacagc aacctttgga
    21601 tattacggaa agtggaacgg tagaaggttt attagcggaa acgaaggtaa cttacactat
    21661 tacgccagct gaaggtgaac aaattgcttc agtcgctgtt aatggtgcca aagaagtaaa
    21721 ttatgatgca aagaccttta cagtaggtac gaacaattta tctattactg cagaatttaa
    21781 agctggaccg gatacttcaa cagagaaacc aactgatcct agtgaagaag tccctagtac
    21841 accagatccg gaaacgccaa acaaaccaga tgtgggtaat aacaacaata ataatggttc
    21901 aaataattca aacaataata acaataattc gaacagcggg aattcttcga atcaaacaaa
    21961 cccatctgga tcgaataaca atggaaatac tcagagagaa ccaaaccatc caaacaatgg
    22021 ttcatcgaat ggcggaacga acaatgcttc atctcgtcca aatacagcaa atcaaagcgg
    22081 tatagagaat ccatcttctg cttcttctga ttttgttgta aaatcaccaa ttgatgctgt
    22141 attgcctaca aatacaacga atgtccaaca agcaatcgtt cgagaagcat tcaagcatct
    22201 tggaaaacca tatgtatggg gagcaaaagg tccaaatact tttgactgtt ctggtttgac
    22261 ttattacgta tatatgaaag caaccggtca ttatatcggt ggctggacag gcgaacagca
    22321 atatgcaggt acgcagattc cagtaagtca ggcccaacct ggcgacctcg tcttctgggg
    22381 accttcttcc ggtgttactc accatgtagg tatctatatt gggaacggac aatttatcca
    22441 tgcgcctcaa ccaggagata aagttcgagt aacttctatt tcagatttca cgcctgattt
    22501 tgctgtccga gtaaacttag caggtttacc tgctgcttca ggttcgctga caggcggctc
    22561 atctatttta gatggattag atggctcgtt ccatttcagt caaaaccaaa caactgatca
    22621 gttcttgaaa aagattgcag atgatgcaca ggaaatcggg caaaaagaag gaatctacgc
    22681 atcagtcatg atggctcaag ctatccttga aagtggatct ggaaacagct tattatcaag
    22741 cgaaccaaat cataaccttt ttggtatcaa aggatcatat aaaggaagca gcgtgacctt
    22801 caatacactt gaacaagata gttccggaca aagctaccaa atccgcgcac aattccgtaa
    22861 atatccttct tacaaggaaa gtttggaaga ctatgccgac ttgatcaaaa atggactgac
    22921 tggcaatcct gatttctaca aaccaacttg gaagtcggaa acaaaagact acaaagaagc
    22981 aaccaaatat ttggaaggac gttatgctac agatcgccaa tattcacaaa aattgaacgc
    23041 gatcatcgaa gcgtacgacc tgacaaaata tgatgaaccg aaaaaagaag cagcaacaac
    23101 tgaagaagca aacgctgaaa tcctcaatat gtctaagcga ttcgatgtgc caatcaaatg
    23161 gacaacagat ggcgtgccaa tcacaggatt agaattttca acgataaaac gcgtcaacaa
    23221 cgcttcttcc atcttccgtg tcgcttcaat ctgggatttg tggaacaatt ttacggcaag
    23281 acagatacca gaaacaacta ctcgtacagt taaagctgca actgttcctg tactaacctt
    23341 gttaagttta gacaaatcat tctggcttga tctgccttta aagaaataga ataaattaaa
    23401 aaggggatgt gacactgtca cactcccttt ttaatttatt ctatttcttt atatttattt
    23461 tgtattccgt tacaaactcg cgtacttggt taggttccag agtgacatct ccaaaacttt
    23521 caagtcgctc cgctcctggc agttcttgag tctcaaatgt gataccgcca tgatttacta
    23581 atttattccc gcgcatttcc ggtccatctt ctccaaaatt tgctgtaaaa atcacgattc
    23641 ctgaagcatc tgtttttact tggatcgata ctttttcatc tgggcttgtc aattccgcag
    23701 catttagtaa accagattgt tttttcaaca aaaatggatg atcgatgccg cccactatca
    23761 ttgattggcg aaaatcactg gcaaagacct cacctaattt tttaggacgt tggaagtcaa
    23821 atgctgtgcc acttactgaa actacttctc ctgtaggcgt tgtatcttta ttgagcgtag
    23881 caaataatcg gctattcaac caaagtatat gttcgtcgat tgactgtgct ggatcaccgg
    23941 ttaaattgaa atagacatga tttgtaggat tgaatactgt tttgcggtca ctgatccctt
    24001 ggaccgtcac tcgccatgta tcatcgttcg tcagcgtata ccgtacttct acatctaaag
    24061 ttccaggaaa tccgttttcc atatctgggc tagtctgata gaaaatgacc gatgcttcgt
    24121 tttcaccatt gatgactgta taatgccact gcttggcttc aaagctaggt gcaccaccat
    24181 gtaaacaatg accagtgtcc gggtctgttt ttacttcgaa cgtttcatca tctaatttga
    24241 atgtgccatt cgtaatccgt ccagccatac gtccgattga agcaccgata taagggtctt
    24301 tttctagata ttcttttgct tcatcaaaac ctaagatcaa ctctcgtttt tcattatcga
    24361 ttattgtttg aaaatgaaca acccgtgccc caagatcact gacagacaaa gatgtcccat
    24421 tttgattcgt gatcgtaatc aagtgatagt tttcgccaaa attttgttca ttgatttcca
    24481 tgttccttgc accctctttt ctttcatttg cactgattcc agtatacatg gaaaccgttt
    24541 tcttaacagc ttattccgtg agtaacgaga aaaaatttac tatattctaa taaaagaccg
    24601 tgaaaaaaag gttgtgacaa aaatattgtc acaacctctt tttccgaaca aacggtgttc
    24661 aaaagcttgc atctgcggta ataagcccaa ccaaacgaaa aatatgagga gctatttttg
    24721 cttggctgtt cttattactt gatgcaggac agctttttca caatctcttt ttcaatacga
    24781 ttccagtata taaccatgtc gtcagtacat agtagatgaa atacaatacg aagaatatcg
    24841 taaacggaac ccaaatatct ttgtatggat tttgcatgaa tagaccaaac atttgtaatc
    24901 cgaataagac atggactaca cctaagattc ctggtgctaa gaataacacg cctacttctc
    24961 tacggatcga ttgtttaagc aacccgcgtc gtgttcctat cttttcaagc atttcataac
    25021 gagcaatgtc actcttgctt cctgacaaga tcttgaacat caaacagcta gcaagcatgg
    25081 tcaagaaagc taaacctagg aagaatccca taaattcaaa accagagaat agaccattat
    25141 acacttcata catttcatat ttctggttgc tgtactctac tttttgcaaa gatggattgt
    25201 tcattttatt ttgagcaaca agtgtttcga ttggtttcag gtttgcttgg aagtctttta
    25261 cctgaactag ctgtaaagtg gattgtggca agttcagttg atcaaattct gattgactga
    25321 ctaccttgat ttctttttct tgctgttccg gcaattcata gcttcgaagt tcctcttgta
    25381 cagtcagttc attcattttt ttagcaggaa ctttttcttt cgtgatcttc ggcggtgttc
    25441 catcttcatg ttttatcatg atcaatggtt gagccgcaaa ttcacttgca ttatagtaaa
    25501 tcgttcccgc atcttctttt tgagtataag aagcagaaag tgttggtgaa agttctttga
    25561 ttttttgctg atcttctgcc cgaggattat tcatcactag atcatatcca gaattgtttt
    25621 ctgtcaagtc tgcaatttca tttttaaaac ctaatcctac cgtcaaagcg cccagtgcca
    25681 aggcaaacag catagcgacc attgagagca tttgtgtata ttcacgaata cgaaagttta
    25741 actgtgacaa tgtgaaattg ttcaattttt tcaatgaaat ctgttctgat ttctttagta
    25801 atgataaaaa gaaaatgatc acagaatgga aaatgaaata agttcctaat acgatcgtaa
    25861 ctaaggctac ccctatacca aagacttgat aggtccccac gtgtttcatc atatagtaac
    25921 cgcagcctag aaaagcaatt cccagtacta cttcaaggaa aaacaagaat ttatgctgct
    25981 tgattcttgt tggtgtctga tccgcacgaa tcaatgctaa aatcggtttt ttgacaatcg
    26041 aaaaagcatt gacaacagca gctaataaaa acaaaacagc aaaaaacaaa acagtgatca
    26101 acaacccgtg aatactaaaa ggtgtaaaat gcgaaatatt gagatctaac tgatccacta
    26161 ataatcggtg gacgatactt gtcaatccta caccgacagc tgaacccact aaagtagctg
    26221 cgatccctac taagaatgtt tcagaaaaaa tcatctgtgc gatttttctg ccttttgctc
    26281 ccagcatcat aaacattgca tagtcttttt gccgcatcgt catcaaaaag gaatttgcat
    26341 ataaaatata aacgaatgtg atgatcccta gtaaaacaga accgaatcgg aaaatgataa
    26401 ctgtagccgc aacgatcgta ttacttttca aaaaagcttc gttgcttgcc attgattcaa
    26461 acatgtaaaa aatagcagat gccataacta atcctgagaa taacaccaag tagtctctta
    26521 aacggctctt gatcccagta agtgataatt tccaaagcat agtcaatctc cccctactgt
    26581 tccaagtttc caagaataga tagtatttct cgatagaagg aatcacggct ttgatctcca
    26641 cgtttcactt cttgatggat accgccatcc ttgatgaata aaatacgttg gcaataactt
    26701 gcagaaaacg gatcatgcgt cacaagaaga atcgatacat gatcttttgt attcaattcg
    26761 tccatcgtat ctaaaagatc ccgggcactt ttggaatcca gcgcacctgt aggctcatcc
    26821 cctaatagaa tcgttggttg tgtgatcaat gcacgtgcgg cggcgacccg ttgtttttgt
    26881 ccaccggaaa tctcagaagg atagctttcc aaaatatgag agatggataa acgttctgca
    26941 attttttgga cacgttgctt gatttctttt ggtctgacgc cttgtaaaga aagaggaaca
    27001 gcgatatttt cttgtgctgt caagctttct aataaattga aatcttggaa aataaagcca
    27061 atctcattcg cacgaaaatc tgctagttga tttcctttta atgtggtcac atctttttga
    27121 ttgattcgga tatgcccatc tgttggttta tctaatgtgg ataaaatatt caaaagtgtc
    27181 gacttaccag aaccagaagc gcccatgatc ccaataaatt cgcctttttc tacatcgaag
    27241 ctgatgccgc ttaatgcttg cgtctttttc tcattgtttt ttccgtatac ttttgttaca
    27301 ttctgtactt cgactatttt gttcatttct ttccctaccc tttaattagt ttttccagtg
    27361 ctgttttcgg cacgtctttt ttttcgactt cttcatacga agtgacacct ttatttttgt
    27421 tccaggtgat ttttaaatat gctcctttac gaagcggtcg agtcaattgt cccttgaagt
    27481 ccagttcttt ttccttaccc tctttcgtat agccaggcag gatatatcta tagttgactg
    27541 tttcttgtcc agagtctgat tttgaaactg tttttgtacc atctgtcgta atttgtacat
    27601 agtattcttc tccacccata actacgtaat ctgcgatttt cacccctgca agtaccacaa
    27661 cgatgaaaac aagtagaccg atcagaagtt ttttcacttt ttccccttct ctcttacttt
    27721 atatactgat tatagaaaaa agcgaacaat tctgccttcg aatcaactat cattcttctt
    27781 tcaattttgt cattttcttt aaaacaacta aaaaaagagt tcaagacaat aatccgtcct
    27841 aaactccttc ttcctatctt acaaaaagta tgtcacttac ggtctttcat gtcgcctgta
    27901 ttgataacag gttgcgttcc tttgtctgta atgattgaga caagtaaatt attgatcaat
    27961 tggactttcc gatcatcggt gaaattgatt tcttgtccat cttcgatttg ctctaaggcc
    28021 atttgagtga ttgtgacagc tccttcaaca atggtttgtc gagcagacaa aatggctttt
    28081 gcttgttgac gttggagcat ggcactagcg atttctgttg cataggctaa atggttcaag
    28141 cgtgtttcga ttacttcgac acctgctact gctaaacgct cttgcagctc tttttgcaac
    28201 tcgtcagaca ctgccgtcgt gtttcctcga agcgtcaaat cattctcatt gaatgtatca
    28261 tacgggtatt ggctagcgat atgccgaatg gctgtctcac tttggatttc tacaaaatct
    28321 tgataatacg ctacatcgaa taatgccttt gctgtatcaa cgactttaaa gactactact
    28381 gctgagattt cgatggggtt tccatccaaa tcattgactt ttaaaacaga actattgaaa
    28441 ttccgaactt tcaacgaaac agtcattttt tgtgccaaag gtatcgtaag gaaaaagcca
    28501 ttttctcgaa tcgtacctaa atattgtcca aaaaacaaaa ttacttttgc ttgattagga
    28561 ctgactacag ttgccgaact taacaacaat aacgtgatca accaaagaaa aatacttaaa
    28621 aaaagtgccc aaactttcgc ttgccacata cctaaataga agaaaaacaa tccaactaaa
    28681 gctaatacga ccaatccgac aatccctgca taaccattga tataaaatgc tcttttttct
    28741 ctcatgctac ttcctgcgct cctttatcct tcaataaata tctaatgtta cttttttaat
    28801 ttttttttcg aatacgcgcc attacacctt ctagttctaa ctctttgtct tcagtgatgt
    28861 accaaccgct tgcctgtgtc cctccggctg cctgcggtaa ataatccaat tttgttcgaa
    28921 cccagtgctt ttcttctgta aaatagtctt ctaccaagac ctctagatcc atccctgctg
    28981 aaagaggcaa atcttcccga acagatttaa agataaatcg ttccttcttc ccatcatact
    29041 tcaatattcc tgtatcgata atcggtaaag aataataatc cagctctttc ttcaccgtca
    29101 ataaatgttt gaaaacttca tggtacactt gctctaattg gcgaccttct gaattgttcg
    29161 ggtaattaac catcactttt tctttgtctg gatcatagaa ggtttggctt agttgagtga
    29221 tataagtatg taatctttcc atttctgttt ttaacttttc tctttgacct tcttctacct
    29281 tcatatactc tttcaccctg ttttcttttt agatattttc tttcttattt tactatagtt
    29341 atgtgcgtta agcgatgaaa aacagcaaag attggaagga tctttgctgt tttttcttaa
    29401 aatatccagt tgagtacagg atcaatctgt ttcattgtcc tcttgatccg tcgtaatatt
    29461 gatcgatgtg tctttagcag tgatctttag ctttttctgt ccttgttcta acaaagtatt
    29521 tgttattggc tggtagtctt tttcaatata agattcacca gacgtttgga tagtatagcc
    29581 actgttttcc atctcatgca aagataaatt gccaccgttt aggatgactt ttccttcttt
    29641 gctgatcaaa ctgtcttcta gatggaagtt gctgttttca cctgtgacga tcaagttatc
    29701 cacattggcc tcatctaatc gaagtgagcc taattcatct ttcgcagtta ttgttcctcc
    29761 tgtaaattca ttgaacgata cccagccatc atgtgtctta gtattcactt ttttgattga
    29821 tacttcgttg atatcaattg cactattatt cccttcgatt gtcaattcag ataattcatg
    29881 atctgcaggg acaacaatag tgatttgtgc acttgtgtct tctaaactaa tgattgcacc
    29941 tgttgatttt ttgactgcat tcacagtcaa cacgccattt ttctccttta tttctggctt
    30001 ttctgtctta tcataagtcg tttttatctc aaaatccaat ccgcgtatga ccgaaactgt
    30061 ttgattttct gcatggatga cgattttgtt tgcatccttg attttttttg tctcagtaac
    30121 catatcgatc aaccgaggac cattatccca agtcagactc ttttgagcgc ctaatgtata
    30181 agttgcacct gctaggaggc caccagtaag catcagacca ataccggtaa tcaaaaaatg
    30241 tttcaatctc aatttatgtg tcctccttca aacgcccgct gaatgcagat ctctttttgt
    30301 aataaaacgt cgtcccatcc atttaacaaa gttcatcatg acataaaaaa gcccttttgt
    30361 tcctttcagc aacagtggcg aaataaatac tgcgcttcct gtggcgaaca gaccgacacc
    30421 gataaagaat aatccactca gaatcgattg tccaaacaca ctgattcctg agatgatcat
    30481 gaataggcca acacctaaga tactgataca taaaacatag atactaaaaa tgagcgctag
    30541 taaagcaacc aatagtcccc caataaccaa tataaacccc agtgctagtg gaatgaggac
    30601 aggagaagca aataaaccga taatgattaa ccaaatcagg cgaatttgtc tttttggatt
    30661 tttcactaac tcgttttctg cttgttcttc ttctgaaaag taactgattt ttaattttaa
    30721 ggcaaactgc tttggtgtac catattcatc aatgatctga tctaatgttt ttccagaatc
    30781 taaaaaatat tcctcataat actggatcaa atcaaaacga tcgtcttcag gaatttcttg
    30841 aagatgatcc acaacttcat tcaaatattc attcatttgt gctctcctcc aataaccggt
    30901 ctaaagaatc tcgaaaaaca atccattcat caataatttc ttctaaatga cgacttccca
    30961 ttggtgtcaa cgagtaatat cgacggtttc tgccttcaaa aggttcatca taggtctcaa
    31021 gatatccttc ttttttcaat cttctcaaaa ccggatatag tgtagattca ctgacagaga
    31081 gactttcttg tacgattttt gttaaggcat acccatacat atcttccttg cttaatgctg
    31141 ctagcacagt accatcaaga agaacagttg gaatctggat gtgcattacg tcaccttcta
    31201 ttctcaagtg taatatttta tttcaatcta tattatacaa catataatat agtttcaaaa
    31261 tcagtttgtc aaatacaaaa aaactgacta aaagatttga tcctttttag tcagcaaaaa
    31321 atggcttctc tttgattttt attataacag tggcataatc caatttgtcc acatccagct
    31381 cagtggcatg ataacgatca ttgcaggtat catgtcagct actgggaaca ttttcacgtt
    31441 gatcattcta aaaccggtag cgaccatcaa gaatccgccg caagctttaa aatctaagat
    31501 catgtctggt gtagtcaatg gataaataaa ttttgccaat aagaacaaaa tataaaaaat
    31561 aatgaattgg ggaattgcta tcacagaaac gacataccct aaattacacg caaaaatagc
    31621 tgctgtgaaa aaatcaagga cagatttaga aatcaaaatc gtactgtctc ctgtcatccc
    31681 agaatctaaa cttccataga tccccgtacc acttgcacaa aatagaacaa tgaccgtcac
    31741 taatgtgctg ataaattcat cgtgggtcat accaagcttt tcactaggga agattttaga
    31801 aataggtact tgcatcagcg cagccccctt atttatccca ttacctaaat gaacaatcaa
    31861 accaatcgct gttcctatca ctaaagcaaa aataacagcc ggcatatttt tcatcggcgc
    31921 aatggaatag attcccatcc ccatcgaaca cacaccaaaa accatcgtca gctgtgcttt
    31981 aaaatgttca cttaatttat ttcctactaa tccgccaatt agtccgccaa acaaaacgga
    32041 acctacattg atcaaaactc cagttggcat caaaaaactc ctctcttttt ctacgaagcg
    32101 aaaaaaatca gaaaaatttc tgtaattatt gctttcgctg caagaaagat tgtaacagac
    32161 agagaagatt acaccaattc attttttgtg ttaaagtatt ctttattgga ataagtagga
    32221 ggaatatgat ggatatccat aaattcgaag tttttcttga tttagccgaa acaatgaatt
    32281 tcaccaaaac tgctgatcga caattcacca cccaaggaaa tatttctaaa cagattcttt
    32341 cgttagaaac agaattagac gtcaaattat tcgaacgcgc ccatagaaaa atcgaattga
    32401 ccgaagctgg aagcttattg ctcccatatg taaaaaatgt cgtagaacaa taccatgcta
    32461 tgcaagaagt gcttgaaacc tatacgaaag acaacaatct ttcattaaat atcttaacga
    32521 taccgacaat gatcaattat aaaggttttt ccaaaatcac cgagtttttg aaacgccatc
    32581 ctgaatttac agtccagttg aaagaagtgg aaagtgtcga attaacttac aatgacgcca
    32641 atgaacatag tgacacgatc cactttgcta gaagtttcca ggccccacca agttcgattg
    32701 agtggttgcc tactgaaaca gacgattttg tagcagttct acctaaaaat catcctttag
    32761 ctagtaaaaa gaaattggat ctaagcgaac tgaaaaagga gaactttttg ctccttggcc
    32821 ccactacgaa cttgtatcaa cctgtactag atctgtgtcg cgaagctgga tttgaaccaa
    32881 aaatctctta taaaggagca agaatcgact tgatcatcaa tatgattgca aatgacatgg
    32941 ggattgctat tgttatggaa aaaacagtca agaatctatt aaaagaaaat actgtgattc
    33001 tccctatttc tccaacaaca gagagttatc ttgcatttac tcgtaaagtc ggtgagcatt
    33061 ctttggcttc agatacattt tgggagtatt taaatcaaga agaaaactaa gccctacatt
    33121 ttctgtccat ctatccaccc aaaaaaagag agcgacgcat gactttcgct ctctttcttg
    33181 catcatgtcc ttgtttcaat gacacctcta acatttctcg tagttcaata agaaagcagc
    33241 gatttttatg ccaaaagaac cgtaagaaca tttccctaat cacaaaaaaa cgactaaaaa
    33301 cccctaaaaa ccttcaatag aatttttagg ggttttattc tttttcctat tgtttactta
    33361 accgtatcat tgctgtcgtt cctactcctt cgatactgct ataatcaata cgtccatcat
    33421 gcagttctag aattttttta accagtgaaa gtcctagccc attcccagaa atttgacgac
    33481 ttgtatctcc ttgataaaat ttttcaaaca ttcgatctct ggtctcttca ttcattccta
    33541 cacctgaatc ggtcacttcc agtacaatct ctgtggctgt ctcaaatagt ttgatatgaa
    33601 tctgtccatt gatttgattg tactttatgg cgttatccat gatattcagc cacacttggt
    33661 acaaaaactc ttcattgcct gtgtaattta ctgcagcaag ttcgatatcc aattctagct
    33721 gttctttctc ccatttaggc tgaaaaaaaa cgattacttc tctgatttgt tcatctaatc
    33781 gatactcttt cttttccagt tggatacgct ggttttccag tttgttcaat tttaagatgt
    33841 tctctgttaa ttgtgaaagc tgcgtgatac tttcgataat ccgatataaa aatatttggc
    33901 gttcttcgtc agagagattt ggggcttgta acaattgaac atatccttgg attgttgcta
    33961 gtggtgtttt gaattcatgg gatacactgg acacaaagtc attcctcagt gtctcgatac
    34021 tattgagttc ttggaccata acgttgaaat ctttatacag ttgctgtact tctgctactt
    34081 tctgctgttc atccattcga atcgaaaaat ctcccgttgc taccagactc atatttgtcc
    34141 ctagcgcact gattggatgc aggatacgcc gcccaacaaa aatcgatatt cctgtaccca
    34201 cgaccatact gaaccccgca aagacgaata acgggtataa cgttggtttt ccagccgatt
    34261 cagcaggcga gatagaatgt cgagacaata agaaaataaa accgagaaaa cacagcagtg
    34321 tcactaagat cgaaatgaag acaatactag caaaatagat ccataattgt gaaaatagct
    34381 tttttttcat ctttaaataa ccgccttata gcctagtccc cgtactgtga tgatttgaaa
    34441 atcttccgtc ttttcaaaac gggtccttaa acgtttgata tgtacatcga tcgttcgttc
    34501 ttctgtattc gtatctaatc cccaaatatc atccatcaac tgttggcgag tgaagatctt
    34561 gttgggataa gacagtaatt tatacagaag cagaaattct ttttgaggca gaatcaacga
    34621 atgctgatct tgtaacactg tataagcatc tagctctaat tttgtttgtc cgattatcaa
    34681 gctactgctg taattgatct ttgaacgtcg aagcaatgct tccacacgta ggatcatctc
    34741 attgacatcg atgggttttg tcatataatc atctgctcct aatttgaacc cgcgtttctt
    34801 atcctcaaaa tcggcctttg ccgtaatcat tagaacaggt gtgtcaaatc tggtgctacg
    34861 taatgagtct agcaagtcat agccatccat tttcggcatc atgatatctg taatgattaa
    34921 ttctatacgt gtcgcttcta gttttttcag cgcatcctct ccattcaatg cggtgatgac
    34981 tgaaaagccc actcgttcca acacagaacg gtaaagcaac tgtaattgcg gatcatcttc
    35041 tactactaaa atacgattca ttgatctccc tctgtttttt gaaaaatttc tagatttttt
    35101 cttgtagttc atcttcagtt aacatttatt tcgtatacta cgatcattgt tctgatatac
    35161 ttattagtat accgaatatt tcaatacggg agaagggtga ttatgcttca attaaaagat
    35221 ataaaaaaat attataaagt cggcgaaacc accaccaaag cattggatgg tgtgtctgtc
    35281 gctttcagac aaaaagaatt cgtagcgatt ttaggtccta gtggttctgg taaaacgact
    35341 atgctgaatg tgattggtgg actagataat tatgattccg gtgatatggt aatcaacgga
    35401 aagtctacta aagactttaa ggacagtgac tgggatgcct accgaaacaa ctctatcggt
    35461 ttcatttttc aaagttacaa cttgattggt catctaggca ttattgaaaa cgttgaactt
    35521 gggatgacat taagtggtgt ttctaaagac gaaaaacgaa aacgggcaga agatgcattg
    35581 caccgagtcg gcttgacaaa tcatatgcat aaaaagccaa atcagttatc tggtggacaa
    35641 atgcagcgag tggccatcgc tcgagcacta gccaatgacc cagatatcct tttgtgcgat
    35701 gaaccaaccg gagcgttaga tacagaaaca agtatccaga tcatggaatt gatccaagag
    35761 ttatcgaaag aaaaattagt gatcatggtc acacataatc ctgaactggc ccatcaatac
    35821 gcagatcgaa tcattgaatt ttctgatggt aagatcttaa cagattccca tcctcacatc
    35881 gaacgaccaa aagatgatca atttaactta cgcagaacaa agatgagttt ttggacagcg
    35941 ttaaagcttt ccttcaacaa tatccgaaca aaaaaaggac gtactttctt gacctccttt
    36001 gcttccagta ttgggatcat cggaatcgcg atcgttctgt ccctttcttc tggattccaa
    36061 aaacaaatcg ataacacgca agctgaaacg atggcgaaat ttccgattac tatttctaag
    36121 gtaacgacta accagactcg tgacgatgcc ggattgggtg caagcaaagc ggattatcca
    36181 gacagcaaaa cgattactgc aaaagtcagc gaagaagata aagcacagca cacgaataag
    36241 attgatcaaa catacgtcga ttacgtaaca gacatcgatc ctaacttaag taataatatc
    36301 ggatttaccc gtactacagg aatcaatctt ttacgtgatg taaatggcaa agtacagcct
    36361 gtcagcttct cgaatcaaaa tcctgatacg gaatctcttt ctttatctag tacgatgtca
    36421 gcaatgacag gtgtgggagt gtcaagtttc cctacacagc ttgacactag caaagaaaac
    36481 tttttaaaag acaattattc tttacttgcc ggaagttatc cagcctcagc aacagatgtc
    36541 gtgctgatcg tagacggcaa taataatact aatatcaacg cattgaagaa tcttggattt
    36601 gatgtgaaag aagacgaaaa acttgatttt gatgatatcg ttggtacaac attcaaatta
    36661 gtaaacaaca atacttacta tacaaaactt ccaactggga attttatccc taatacagat
    36721 tatgatgcga tgtatcagaa tgcttctgat gaattgaaga tctcggggat cctacgcgtg
    36781 aaatcttctt ctacaatgaa tctcttatct ccaggaatcg cttatagcga tcaattaacg
    36841 actcaaatcg tcaacgaaaa caaagaatca gaaatcgtca aagctcaaag agacagtggt
    36901 gtaaatgtct taactactga aaaagttgac gaaaatgcca aacaaacatt gcttagttat
    36961 ttaggtggag acagcttgcc ttcaagtatc atgatttatc cgaacaattt tgaagacaaa
    37021 gaaaagatct tggattatct agatgattac aataaaggca aatcagatga agataaaatc
    37081 atttatactg atttagctgg aacgatgact gaactgactg gcggattgat ggatgctatc
    37141 acttatgtcc ttattgcttt tgcagggatc tctttagtaa caagtatgat catgatcagt
    37201 atcattactt atacatctgt gattgaacgg acaaaagaaa tcggtgtact aaaagcttta
    37261 ggtgcacgta aaaaagacat cactcgcgta tttgacgcag aaacgtgtat tttaggtatt
    37321 tcttctggga tattaggtgt gtttattgca tggctagcta cgttccctat caatagcatc
    37381 ttatacaaca tgacggatct aaaaaatgtt gctcaactaa atcctgtcca tgcgattatt
    37441 ctagtgatcg tctctactat attgacgatg cttggcggtc atcttcctgc acgaatggca
    37501 gcgaaaaaag acgccgctat cgctttgcgt gcagaataag gttgtgacaa ccacatttag
    37561 atttgagtca taagagcgct gaaatagtag aaaacagcaa gaaacgagga agtaatatgt
    37621 tccttgtttc gcgctgtttt ttttaattat tttttataat tctggtatac ttttctttcc
    37681 tttgtaccac aactcttctg gcgtatacct gtcttttcca tttatgaata ctgttccatc
    37741 tgcttcaatc gttacttcag tcccaatcca catattacga gaaagtgcga gaagattttt
    37801 tctttttcct cttccttttt ttccaaattg caaggcatcg gttatctctt ctgtccaatg
    37861 agatttcacg tattttactt ctccgttttc aaatgtaact ttcaaaatat tcgctatatt
    37921 ttccactttt actgctttag gaaatgactc ctccattttt ttcactttcc ttcctccaac
    37981 actaagtatg cgctttcttt tagtgataag tatatcatag tttattctat tatcaaaaaa
    38041 acgcatccat tccattgtag aatactttac cgaacaagtt gaattgtttt cctctttttc
    38101 accttttact atagataggt aaagacaact aaggaggaat ctctcatgac agatcaaccg
    38161 tatgatttaa gaaaagtcat cgaagaacta aaaacacttc caggtcaata tcacgaaaca
    38221 gatattgaaa tcgatcctga agcagaatta tctggtgttt accgttatat cggtgctggc
    38281 ggtacagtaa aacgtccgac tcaagaagga ccagctatga ctttcaacaa tatcaaaggt
    38341 ttccccggca cacgtgtgaa catcggaaca atggctagtc gtaaacgtgt aggtgaaatt
    38401 ttgcaccatg attatcgaac acttggtcgt ttcttgaaag acgctgtaga aaatccaatc
    38461 aaacctgtga aagtagacaa agcagacgct ccagcacaag aagtcgttca tctagctacc
    38521 gatgcagact tcgatattcg caacattttg cctgcaccta caaatactcc tgaagatgct
    38581 ggtccataca tcacaatggg tgtagtctta ggatcagatc cagaaaaaac aatgagcgat
    38641 gtaacgatcc atcgtatggt tctagaagat aaagatacga tcggtatgta catcatgcct
    38701 ggcggacgcc acattggtca cttccaaaaa caattcgaag ccttgaataa accaatgcct
    38761 atcactatca atattggttt agatccagca attgccattg gcacgacttt cgaaccacct
    38821 accactccac ttggctacaa tgaactatgg tgtgcaggag ctttgcgtaa cgaacctatt
    38881 caaatcgttg atggtatagc agtcgatgaa gtgggtattg ctcgtgctga attcatcatt
    38941 gaagcagaaa tcatgccaaa tgaaacaatg caagaagata tcaacacgaa ctcaggaaaa
    39001 gcaatgccag aatttcctgg ctatactggg gatgctaatc cagctgtaca agtagtgaaa
    39061 gtcaaagcag ttactcaccg aaaagacaat ccaatcatgc aaacaacgat tggtcccagt
    39121 gaagaacacg tatctatggc cggtattcct acagaagcaa gtattcttgc cttggtcgat
    39181 aaagctattc caggaaaagt agtaaatgtc tacaatcctc ctgcaggtgg tggtaaattg
    39241 atgaccatca tgcaaatccg taaagaaaac gaagcggatg aaggtattca gcgtcaagca
    39301 gctattcttg ctttatcagc cttcaaagaa ttgaagacag tcattttagt cgatgaagat
    39361 gttgatattt tcgacatgaa cgatgtagtt tggactttca acactcgttt ccaaggagat
    39421 aaagatatca tcgtgatccc aggaatgagg aaccatccat tggacccatc agaattacca
    39481 gaatataatc ctggctctat tcgtttccgt gggataagtg caaaaactat ctttgacggt
    39541 acagttcctt tcgatatgaa agaacatttt gtacgtgcaa aattccaaga agtagaagat
    39601 tgggaaaaat atttgaaata atgaatgatc tgcaactgtt ttgacatcat aaaaaggagt
    39661 gcggaaaatg gaacaattgg cacaacggaa gaaaaaaatc gtgattggtg taagtggcgc
    39721 ttcaggcacc atttatgcca tcaacctagt gaagaaacta aaagaatatc cgatgataga
    39781 aacacacgga atcatcagtc catgggcaaa acagaactta aagctggaat ccgacttatc
    39841 actaactgaa ttcgaaagcc tgtttgatta ccattattca aacaaagatt taggtgctgc
    39901 tgtcgccagc ggatcatttt tgaccgatgg aatgatcatc gtaccggcaa gtatgaaaac
    39961 agtcgcaggt atctctgttg gtttaggcga caacctgatt gcacgtgctg ctgatgtaac
    40021 aatgaaggag caacgaaagt tagtcattgt tcctcgtgaa acgccattaa atgccattca
    40081 cttggaaaac ttgactaaat tagcacgact aggtgtgcaa atcataccac caattcctgc
    40141 tttttataat cagcctcaaa cgatccaaga tcttgttaat caccatacaa tgaaactttt
    40201 ggatcaattt gaaattgtaa atgagcattc aaaacgttgg cagggtgatt aatatggaaa
    40261 aagaaacgat agttgaagta accaaactag gtttcacgat ccaagctgct gttaaagtaa
    40321 tcggtaaaga cttattgatc actttaacag gcggagatac accacatatc ggaacagtca
    40381 ctacattttc tcgtgataca gagatgcaaa ctgtacgttt ccctagccac gatggtcggt
    40441 tccataaaga cgatgtctta gccgaaaaaa tagctgtgat catcaaaact gccgttccgg
    40501 gaagttgtac gatcacttcc ggtatccatg ttgaccatat ctccaatgca caaatcaacg
    40561 cctcttttcc gatgtcagaa gagttaggtt acaagatttt agattggttg gaaaaaatag
    40621 atttccatat caaagaacca gtttattata aagatggtga aaaaccatta tgaaagaaga
    40681 ggttgtgaaa tcagcgttat gacctgagta tgagagaaaa aaatggaaaa atagcttctc
    40741 atattttgcc gtttttgagc taataccgag ggacagctga ttgaacgccg tttatcaaga
    40801 ggttgtgata aagccgcttc gtttcgagta gtaagaaaaa ttttgtaaac atgggtttcc
    40861 acatttttgc ataaatttga cttactaccg agaaactggc ttttgaacac cgtttatcaa
    40921 gaggttgtga cacgtctttt gtcacaacct cttttatttt tgcttcactg taactgctac
    40981 aatatcaccg atttcttttc cgatgttttt acgaatatct tttcgtagtc caaggatgta
    41041 gcagactgaa ccatctggat ttttcacgcc catattcacg atactgcctt catacggcac
    41101 attgtcaaaa gttgcttgga ctttaactct tccagcaccg aattcttttc ttatatcata
    41161 cggaaaaata atatatgccc cgcccttgcc gacttcggaa gcatagattt ttgattcaaa
    41221 agaataaatt tccctcattt tatttctcct attttttaca tctagtatag catagcaaaa
    41281 aaaagaagga actgtgacaa aagtcttgtc gcagttcctt ttttcgaata aacggtgttc
    41341 tcctgccaac tcctcggtca caagtcacaa tagtcaacaa acatgagaag ctgttttttg
    41401 aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctcttcc ttaaacggtg
    41461 ttcaaaagct tgcatctacg gcactaagcc caatcagatg aaaaatatgg agtgctattt
    41521 ttatctgatt gttcttactg cttgatgcag agcagctttt tcacaacctc ctacatggtg
    41581 ttcaaaatat tattcgcctt ttgcttcttt cactaatttt gcgaatgctt gttgttggaa
    41641 ttcagcagct aaggctttcg tacgttgttc ttgctctgct ttgctcattt ttggattttc
    41701 agtcattgct tttaccatac cgtcttgaac ataagctttt gcttcacttt ccatcgtact
    41761 ttgctgtttc ttcactaatt cagctaactt ggctgcttgg tccgtactta attctaccca
    41821 tgtctctggg attttgaatg tattcactcg gctgtcatat tcgtgattgt tatcagcaat
    41881 attgaaccag aatttataca tgtcgttttt gtattcccaa taagtagttt tcgtcacttt
    41941 ttcagcatcg ccgtctgtct tttctacttt atttgtttcg ttatccgtac cagttgcttt
    42001 tggtttttct tgtttttcat ttgttcggta aagatacact ttttcttttc cattccctaa
    42061 agctttatac aaaagcatat ctgctccttg ggaatcagca ctggaaacaa ttttttctgt
    42121 ttttgtttcc gttacttttt ccattccaaa gtgattggac aaattagcga cgatcaaact
    42181 tagtgaagcg acgaagatta gtccgaaaat caaagataaa aaggtttgcc atgttttttt
    42241 agcgaacacg ttcgttaaag caaaagcaag caagctgaca atcaaaactc caataatcat
    42301 gcattatccc ccgctttcat tagaacaggt tcttttttct tcaataaaaa ggcaataata
    42361 aagccaagaa tcccaaagat gatcgctacg ataaacgcgg catggtaacc tgacagtgtg
    42421 gcattgattg cctgatcttt ataagctaat ggcgtattat ccaatacaga tttgcttggg
    42481 atatttgctt ttgtcacatt cgtcaacaca ctgatcaaaa tagctgtacc aatcgagctt
    42541 gcgatttgac ggaatgtatt atttaccgct gtcccatgac tgatcaagtt atttggcaat
    42601 gcattcatac cagaagtcgt taccggcatc atgaccatgg agatcccaaa catacggatc
    42661 gcataaagga tcacgatata taaaactgga gtcgtttttg tcaagaaagc aaatggtgca
    42721 gttgccgctg tcaaaatgaa catccctgtg atggctaaac gtttcgcgcc gtatttatcg
    42781 aaaatcgcac ccgtcacagg catcatagcc cccatgatca atgcacccgg caacaacatc
    42841 aagccagaat ggaatgctga ttctccacga atattttgaa tatacaatgg tacgaccatt
    42901 tctgccccta ccatcgccat atttgttaca ccagctaaaa cagctgcaat cgtgaatgta
    42961 gatgatttga atacacgaag ttccaagaat ggatgttcca aatgtaattg acgccatgag
    43021 aacaaggcga tgaaaatcac accaacaact aagaaaccaa ttactttcaa gcttccccag
    43081 ccgtcatctc ctacactaga aaatccgtaa agtaaactac cgaatccaat cgttgataaa
    43141 atagcggata aaatatcaat gctaggattt gacaatggaa taacactttt cattaggaag
    43201 aatgctaaaa ccaagacaag aacaacgatt ggcagtacca taccaaacaa gtcacgccaa
    43261 tggtagttat caatgatata accagataat gtagggccta aagcaggagc aagtccaata
    43321 acgatccctg acatccccat tgctgatcct cttttttctg gcgggaaaat agatagcatg
    43381 atattttgca ataatggcat cgatactccc acaccgcaag cttggatcaa acgaccgatt
    43441 agtaatgtac taaaattagg tgctgtaaag caagtaatcg ttccgatcaa aaagatcgtc
    43501 atggcagaaa gatataaatt tcttgaactg aatttattga tcagccatgc tgttattggg
    43561 atcatgatcc cgttgactag caagaaacca gtcgttaacc attgcacatc agacgctgaa
    43621 atatcgaaag ctttcatcaa tgtaggaaaa gctgtcgtca ataaggtctg attcaaaacg
    43681 gtacaaaatg taccaattaa taagacaaca actaaaagtg tccgattata tggttttccg
    43741 taaatatcta cgggttggtt gttactcata tttctccttc tttctgaatt ttttctgaaa
    43801 ctactagaat actttagtcc taaattcgct atttgtcaac ctacttgaca cataagttaa
    43861 tacggatata attaagggaa gcaagaggac aaaaggagtg acaaaaatgg ttggggcttc
    43921 ccttaaacgt ttgttggaaa atgatcaatt ggttgttggc atcagtgaat taagtgatat
    43981 cgtaggtgtg tctccacgtc aattaaggta ttgggaacaa aagggattca ttcgttcgat
    44041 cgaagctgat gcgaattgtc ctagaaaata tcgtttacct acagtcataa aagtagaact
    44101 gatcaaaaaa tatttagatg acggatttac tttgtcaaaa gctgcagaaa aggcagaaat
    44161 ccgccaaaag aaaatgcacc atgtccgtaa agttttttca aaagcaatca aagatatcga
    44221 attgatcgac gaacgctata cgattttaca aatcggtaac ttcaaagaag agaatgctaa
    44281 gatgtacatc attcatgaca acgagacaga cgaattaact tacaagctcc ttcctgtcga
    44341 tgaaaaagct gactacgaac agttgttaaa agaactctaa acgccactaa tctcctaagt
    44401 accaagcttt ttaataagta gatgctacat aaatacttga aaaaaggcct gtttgaacat
    44461 aagaatatcc gaacggtgat ctgcgtttct ttcatataga aaggaattct ccatcactgt
    44521 tcggatattt ttttattttt ttcggttact ttcttctaat acatctgtta gccaatttgc
    44581 atattctgtt tcccgattga tcgcatgcgc taaaatcagg tagtgtccgt aattttcatg
    44641 tttttctttt tcagtaggaa agatcgtttt ttttcgctct aatagatgaa gtcgtttttc
    44701 ttcatgaagg tcacgctgct gctgaataat ttctactaat gccggatcat tcacgtcttt
    44761 gacgaaatac aatttcagaa caaattcgtc tcgattaacc ggtagttcat tggtgggtgt
    44821 atgaatccac tctgccaatt gttccttccc ttcttctgtt aattcataaa ctttcttttc
    44881 caatttttca cctgtgatct ctacttgatg ctgaatgatt ccttgctctt ccatttttgc
    44941 aagttcagga taaatctgac tatgttttgc ttgccaaaat tctcctattt catttttgaa
    45001 cgattgattc aattcatatc ctgtcatctt cttcttactt aataacccta acaaaatata
    45061 tcgaagtgta ttttttcttg ccatcagttt tccctccttg acaaatcttt aaatccattc
    45121 tatcataaat gagtaatcga aaacatgtag tttattacat gttttaattt ataaggagat
    45181 gcttaaacat gaaagaattt aaagaattgg aagattttat tggaactcac tttatctata
    45241 cgtatgacaa tggttgggaa tatgaatggt atgccaaaaa tgaccatact gttgattacc
    45301 gtatccatgg cggaatggtc aaaggccgtt gggtaaaaga ccaagaagct gatatcgtta
    45361 aattgacgga cggcgtattc aaaatcactt ggacagagcc aacagggaca gacgtggcat
    45421 tggactttat gccaaatgaa aagaaacttc acggaatgat ctttttccct aaatgggttg
    45481 aagaacatcc agaaatcact gttactttcc aaaacgaaca tatcgcagaa atggaagcag
    45541 ctcgtgaaaa atatgaaact tatccaaaat tacttgttcc tgaatttgct acgatcactt
    45601 atatgggtga tgcaggtata gacaatgaag atgttattag cgaagaacca tacgatggaa
    45661 tgccagatga tatccgtagc ggaaaatact tcgatgaaaa ttataaacga gtaaaataag
    45721 gttgtgaaag agaggttgtg aaatcagcgt tctgacctga gtattagaga aagaaacgga
    45781 aaaatagttc ctcatgtttt gccgtttttt gagctaatac cgagggtcag ctgattgaac
    45841 accgtttatc aagaggttgt gaaatcagcg ttatgctttg agtaataaga acgctagtta
    45901 gaaaatagct tttcatattt tctaggctag tgggcttatt accgagaagc agccgtttga
    45961 acaccgttta tcaagaggtt gtgaaatcag cgttttgacc tgagtattag agaaacaaat
    46021 ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt cagctgattg
    46081 aacaccgttt atcaaagatt gtaacaactg catattcaca cagttaaatt agtgacttca
    46141 aaatgaaata atgctcccag caaaaaatta ggctgggagc attatttcgt tattctgttc
    46201 atcaaaaatc agcgttttga ttccatttca tcacaagttc ctcctcattt actgcttcat
    46261 ctttttgctg tgtttgaatt gtaaaacctt gtgaaagata gaaatgaata gctgattgat
    46321 ttttttgata gactgtcaaa gtcagtgttt tattggtttc ttttattttt ttcattagtt
    46381 gcgtaccgat tctttgttgc cggtattccc ttttcacaaa gattcctgcg ataaactgat
    46441 caatcacccc agcaaaacca ataatttctt gatctatttc tgctaagtaa atcactgcat
    46501 ctggtaaagc tttcctaaca gattctactt gattctccca ataagttgat ggaatgaatt
    46561 catgagaatc caagttagca tgcagccaaa tcgatagaac agattccagt tctttggcag
    46621 acaattttgt tgttgtgcgg atcatttttt ctctccttac ttattcattg attttaaaat
    46681 aaaaaccatt tttttgaagc tcttttacaa gttttcgccc ctcaaaaaag tatatcttct
    46741 cttgttttac ttttctaata ccaaaagaaa cagcaacttt aggatcatca gctgaaacga
    46801 ttcgataagt tccaccaggc aattgatcca gcttgacttt cccatgatgg tcgctttgta
    46861 ctgaaaacgg cacaccattt ctagtaagtg tttttttctt atgtttcaaa atgaatgaac
    46921 taccatttac cggtttccct gacgaatcac taataataaa tgaaaaatca agcacttttt
    46981 tacttaatct atactgatag attagtcgtc cgataaacac taacagtatg actacagcta
    47041 ttatcgttcc tgcaagaata aaccattgcc gcatggttct ttcctgattt ccttttcctt
    47101 cttctttttt taccgattcg ttataaggaa tccgatgtcc tgtcactagc aaacgatgcg
    47161 tgttgatcat atacggcgta catgtaagca aggtaactaa gtcttctcct tctgaaatcg
    47221 ttagaacaga cgtgtcatct ggcagtacca cttgtatatt tttaacttga taagccaatt
    47281 tctcccccaa aacagtcaaa ataaacgtgt ctccgttttc taaacgatct aattcggtaa
    47341 ataaccgtcg attaggtaaa ccgctgtgag cagagatcac tgaatgcgtc gaatttccac
    47401 caagcgggaa agaggttcct tgcaagacgc ctgctccatt ttcaaggatc ctaccattga
    47461 gccgatcata aagtgaaata tttaattgga tcttaggtat attgatactt ccgatcagcc
    47521 attcctctaa ttggctggat gttgtacttt catttctgtt cttttcattg aaaggatcag
    47581 taccaggatt gaatccttgg tcagttaatc gttggttttt ctcctccatt ttctttcgct
    47641 gcacttcaat ttcagctgcg gtccgttttt gtacttgttc gatacgtttt tgatcaataa
    47701 aactatttaa agaatccaca taaaatggat ataaagcgat cagtaaccct acgacgatac
    47761 atattaataa aaacaaacga aacaaaagtc gacgagactg tttttgctta ctctgcttca
    47821 catgtgtcct cccttgcaag tttttttgtt ctttctttta ttatatgggt tcaggaaaaa
    47881 aatagaaaat gaaagccgat gaggttgtga aaaagctgtc ctgcatcaag taataagtac
    47941 agcccaaaaa aatagctact catatttttt gttgggttgg gcttattacc gcagatgcaa
    48001 gcttttgaac accgtttaag gaagaggttg tgaaaactgc gttatgcttt gagtaataag
    48061 agcgctagtc agaaaatagc ttctcatatt ttctaggcta gtgagcttat taccgagaag
    48121 cagctgattg aacaccgttt accgagaggt catgaaaaag ctactttgtt tcgagtatta
    48181 agaaaaattc tgtttcaaaa caaggagatg caacaaaact tatgtcgcat cctctctcct
    48241 tagaactttc acttatgttt ttcttgtaaa attcataaat attttcatga attttctaat
    48301 ttcttgccta cctctcgcat aggatatatg atgaatttat ctaaagtttg caaaggagtt
    48361 cgacaattga aaaaatatgg cccattttta gcaatttttt tcattgcttt ggcatttctc
    48421 atgcctcatt tattcacaca taaactaatt ttgggtgctg atgccccatt ccattacaat
    48481 cggttctatg atgccgcgca acaaattaaa tatggggatt tccattattt tccttccctt
    48541 tatggattcc agcaaagtgg caggatcgtg aatgccgttt acggcccatt tttcgcttat
    48601 ttacaaggat tgatcgtgtt gcttgcaggt agctggtttc attatcagat tctttcaaat
    48661 ttcattcttt atcttatttc aggattttct atgctgattt tactgagata tgtcaatgtt
    48721 cgaaattggg taagtgtacc agtagccgtt ttattcatga gtacgtattc tattcaatac
    48781 tggtctatca accaaggatt cactagctgg gggacttgtt tttatccttt atgtatgatc
    48841 cctattgctg atttcgtcct tcataaaaag ttccctgtta tcaaagtcgc tgtctcagtg
    48901 ggacttatga cacagatcca tttactgtct tcgatcatgt tagctttgat gtatatccct
    48961 ttttatcttt attacttttt taaccagact gaaaaaggaa aagcactgct tcaactgatt
    49021 aagtcggtct tgctttattt tgttctgaca gcaaatattt gggcaggatt agctattgtt
    49081 tacagtggga ataagattct tcctcccttt gttaacagag aaatgagtca aaaggcgata
    49141 gatctggatg gcagttattg gctccattac cctaaggcct ttcctatatt gatattatca
    49201 ggttttttgc tttttatttt ctttcaacaa aagaacacct tattccaaaa aatcgtgttg
    49261 tacacaagtc ttgttttctt ttttctttct actagcttga ttccatggac gacattgatc
    49321 gaaaaaaatg tgccttttat tagtttgatc cagtttccat ttcgattttt cgtgccattt
    49381 acgctattgc ttctacttta ccttgccctt tcactgaacc agtggtctga acaaaagtgg
    49441 ttccgtcttt taagtatatt tggcattctt attttttcag cacagacgat ccagaactta
    49501 taccagcatc tggaaaagtg ggaaaatgaa acatttgtca gtcgacatac ttatctattc
    49561 gatacgccgg aagaagcaag gaaaacattc ttcagcaaag atatgtctac cagcttgttc
    49621 gttttccaaa aaaccacacc tgactatctg ccaatctata aggagacaaa agacaataaa
    49681 tacgaccggt ataacgaaga aatactagaa aacgaaacaa cttttataaa aacacatcca
    49741 ggcggtcttt tgacaatcaa gtggaaaaac actggggaca aaactgttca tatccctgtt
    49801 atcgtctacg atcggactgt gctacagcaa aatggaaaaa cattgactga ttatgaagta
    49861 acagatatcg ggaccccaat cgtgaagcag caaaaaggaa tcaacgagct cacgcttcat
    49921 tatcaaacgc caatctattt ctatttcatt ctttctctta ctttgattgg ctggtttacc
    49981 ttgctatgtt tatttattta tcatagatac aagcttttac gtgcttaggc aaaagggata
    50041 aatacatccg atcaaaaaac tctccaaacg gtataatcgt ttggagagtt ttattttaat
    50101 cagttttttt atgttatatg ttatattttt tattcgttca catctaattc gatttccacc
    50161 ccgtagtgat cactgatgat tggactatcg atcccatcaa aaatccgttg atatttttta
    50221 acctgcattc cttcagggac gaaaataaaa tctatacgca atttttctgt attttgttcc
    50281 caaccatcta ttttcttttc cacagtagct gcttttcctt tttcattcgc gacaacatac
    50341 gaatcttgaa gaagaaggca actttctctt acagtataat aaccttgaga gtctactgga
    50401 ttattgaaat cacctaggaa aaaaagtggt acgcgagttt ccaaaaagta gttttccaag
    50461 tttttccact caaaataaaa gccacttttt ttatctgtcc accaagaaaa gtggcagctc
    50521 gagacaaaaa tgtcctgatc atctatcttt gttttcccaa tcaagatctt gcgtgtctga
    50581 taatcttctt tcttttgaaa ttgggagacg gtaaggacct gactttccaa tgtttttttc
    50641 gtaagcagtg catttccttc ttcatattta tcataaccga tgtggctcat ttcccaactc
    50701 caaaaatact cttttccgtg ttcctttaaa agctgaacta aacggtaggc aaaattatct
    50761 ttacggatag gtacttgatt ctttaccgga cagaacttca ttagcttcgc aggttctact
    50821 tcttcagatt ccagtaattg gttgatttct tgtaaagcaa tcacttcata atcttctaac
    50881 aggatcttat ctgctaattc ttgcaatttt ttctctggtt ctggctcaag ccagctatgc
    50941 gtgttgagtg tcatgaattt cattggtttt ctccttgtct tcatttcgaa acaaaagggt
    51001 tgtgacaaaa tttttgtcac aacctctcca gcaaatagtg ttctcctgct aactcctcag
    51061 taataagctc aatggaccag gagctatttt ttgtttggct gtttttatca cttggtgcag
    51121 ggcagctttt tcacgacctc tccactaaac agtattcaaa ctgctgcttc tcggtaataa
    51181 gcccaaccaa acgaaaaata ggaggagcta tttttgtttg gctgttctta tgacttgatg
    51241 caggacagct ttttcacaac ctctccttac attttaatgg agccgatcac tttaccagct
    51301 gtcactgtac ctaattgctt gatcactact tcttctactt tatcgtttgt aaatacgatc
    51361 atgatcgttg gatctttttc ttcgttttgg atcacatcaa gatccatctc agctaatttc
    51421 gttcctgttc ctacttcttg gccttctttg acagcaatct caaaagctgg ctgattcatt
    51481 tggactgtat cgattcccat atggatcaaa acttcgatac catctttcgt ttccagccca
    51541 attgcatgtt tgctagggaa aatacttgtc acttttccag cgatcggcgc aacaacttct
    51601 cttgatgttg gaataacagc aaagccgtca cccatcattt tttgtgagaa taccggatct
    51661 tttacttcag ataaaggaat cacttctcca gaagctgcgg aaactagttc ttgttctata
    51721 cctaagtatt gcttactacc tgcttgtcca tttcctgtag aaaccatttc tggctctgga
    51781 atctctgctc ctgattgcag cagatcttcg atatctgatt tcaagacatc tgcttttggt
    51841 ccataaactg cttggactcc attgtctttg acgatcaatc ccatcgcccc tgctcgtttc
    51901 caggcttctt cagtccctac tttttctcga tcatttacac ttacgcgtaa ccgagtcata
    51961 caagcatcga catctttgat attttctttt cctcccagca aatgaatgat ctggaccact
    52021 tgctgatctg ctgttcctgt tccgctgtta gatacaacgg tttcttcact gtcattgtcg
    52081 taatttccgt tacgtcccgg tgtagcaaag ttgaattttt tgatcaagaa atttgctaag
    52141 aaatacgtaa caacaccaaa agcgatcaca cacaacacga agttgataag atctccacct
    52201 agacccgctt tgatagctaa cggtgtccga gtcagcaatt cgatattccc aaatgaatgg
    52261 acccgcaatg gcaagatatc tgccatcgca aatgcagccc cttggatcac tgaataaatg
    52321 acatataatg gcacagcagc aaacataaac atgaactcca atggttctgt tacacctgtt
    52381 agaaagacag ccaacgctgc tgaaaaatac attgatttat atcttgcttt cttatcagga
    52441 tcgacattac gatacatcgc aaaagccatt cccatcaaga tacctgaaga accaatcatt
    52501 tgtcctactt tgaaacgagc cggcgtccag ttatgcaaca caaactcata ttgcgacata
    52561 tcccctgcac ctttaagatt cactaaatca gtggcccaag ccaaccataa cggatcttgc
    52621 ccaaatactt gtgtccccgc ctgtgcgcct gataaaatct catacgatcc gccaagctgt
    52681 gtatagttga taggaatcgt cagcatatga tgcaatccaa atggcaatag taaacgttct
    52741 aatgttccaa ataaaaacgg tgctagaatc ggtgcgcttt cttgtgattc tgcaatccat
    52801 aaaccaaaat tattgattcc agcctgtacg tttggccaca ccacagcaag aatcaatgcc
    52861 acgattgttg accataagat aacaacaaac ggaacaaagc gctttccatt gaaaaatgac
    52921 aaagcatccg gcaattttct ataattatag tacttattat aagccattgc cccgacaaat
    52981 ccagcgatga tccctacgaa tactcccata ttcaaagctg gtgcttccaa tacacttgta
    53041 aaaaatcctt taaccatgat cttcgtaccg aacagagtgt gggtaaatgc atcttcattc
    53101 gcaagcatgt cacttgtgac accaaagata gccccagtga tccgattgat taaaataaat
    53161 gagatcccag ctgcaaatgc tccgcctgct ctttcttttg cccaacttcc tcctattgct
    53221 aaagcaaata aaatatgaag attaccaata attgcccaac caatattttc aattactccg
    53281 cccgttgtga caagcggcgt ccaatcagga ttgatcaagg gaattgattt ccctatactg
    53341 atcatcaacc cagctgccgg cataactgct accacaacca ttaaagcctt tccaaatttt
    53401 tgccaaaact caaaactaaa tatctttttc attccgttta gctcctttac gcaatcggtt
    53461 tcgttaaacg tattatagcg tgcgttttct tttttgtaaa tgctttattt tttatttttc
    53521 tgtctatacc attctataaa acctataata cgtgtgttcc cttctataat tttctcctaa
    53581 aaatttattt ttttaagctt ttttctatga aatattttct tttgtctatt gacttgtgca
    53641 atcggttgcg tttattatga acgtataaaa cagctcatta ggaggagaaa aatgaaacag
    53701 atcaaacgac tatttgctat tgatccatgg aaaatcagca cgacacaatt agataaaaaa
    53761 aatcttcgac tgcaagaatc tttaacaagt attggaaacg gttatatggg gatgcgcggg
    53821 aactttgaag aaacttactc aggggaccac catcaaggta cttatttggc gggtgtctgg
    53881 tatcccgata agacacgtgt cggctggtgg aaaaatggtt atccagaata ctttggaaaa
    53941 gtgatcaacg ccttgaactt tatcgcgata gatatttcga tcaacgatca gctgatcgac
    54001 ttggcttctt tggaaccaga agacttttac tgggaattag atatgaaaaa tggtgtatta
    54061 tctcgtacat tcacaatcac tacttctact aataaagtac gcatttcctt cgaacgtttt
    54121 ctgagcattg tcaaaaaaga atcagcttat atctatttaa ctatagaaat gcttgaaggt
    54181 agcggaacag tcaaactcgt atcaaaattg gatggaaatg ttcaaaacga agacagcaac
    54241 tatgatgaac atttttggaa tgagattgat cgtggaacta tagaagaaat cggctatttg
    54301 acgactaaaa ctattccaaa caactttggg attgaacaat ttactgttac tgcagcaatg
    54361 cgccatttcg ttaatggaaa atcagtcatc cctgactatc acgaagatac tttagcatta
    54421 catggttgct tgtctgcaga attatctcaa ggtgagacat ggtcagtgga aaaagaaatt
    54481 atcgttctta ctagtagaga tattccagaa gcgcagcaag cagaaaaagc tgtctcagaa
    54541 ttaacgaacc agacaaacaa ttatatccaa gcaaaagaag agcaaacagc ggcttgggca
    54601 gaacgatgga agcttgccga tgtggtcatc gaaggagacg aagaagcaca acaaggtatt
    54661 cgattcaatt tgttccaact attctctact tactacggcg aagatgaacg attgaatatc
    54721 ggccccaaag gattcacagg agaaaaatac ggcggagcca cttactggga tacagaagcg
    54781 tatgctgtcc ctctttatct tgctttagcc aaacctgaag taactaagaa tctgctgaaa
    54841 tatcggcata atcaactgcc gcaagcaatc cacaacgctc agcaacaagg attaaaaggc
    54901 gcgctttatc ctatggtcac cttcactggt gtcgaatgcc ataacgagtg ggaaatcaca
    54961 ttcgaggaga ttcaccgaaa tggcgcgatt gcctatgcaa tctacaatta tacgaattac
    55021 accggcgata cggaatattt gaaaaatgaa ggactggaag ttttagcaga aatcgcacgc
    55081 ttctgggcag accgtgtcca tttttcaaaa cgagcaaata aatacatgat ccacggtgtg
    55141 accggcccaa acgaatatga gaacaatatc aataacaatt ggtatacaaa tacgatcgca
    55201 gcttgggtct tgcgttacac gcgagaaaat tatttaactt atcaaaaaga agctgctatc
    55261 actatcagcg aagaagaact agccaaatgg aaagatatcg cagagaacat gtacttccca
    55321 gttgacgaag aattaggaat ctttgtccag catgacacat tcttagataa agatctcatg
    55381 cctgtatccg atattcccac aagcgatctt cctctgaatc agcattggtc ttgggacaaa
    55441 atccttagat cttgcttcat caagcaggca gatgtactac aggggattta tttcttcaat
    55501 gatactttta caaaagaaga aaagcaaaaa aactttgatt tctatgaacc aatgactgtc
    55561 catgagtctt ccctttcgcc aagtatccat tcgattttag cagcagaatt aggaatggaa
    55621 agcaaagctg tagaaatgta ccagcgaaca gctcgcttgg atttggataa ttacaataac
    55681 gacacagaag acggcttgca catcacttcc atgactggta gctggttgtc gattgtccaa
    55741 ggatttgctc aaatgaaaac tgcccatgat cagttgagat tcgcaccatt tctgccaaaa
    55801 acttggaaag cttattcttt ccatatcaat tatcgcggac gtttattgtt catctcagtc
    55861 acagatgaac aagttacttt cgagttatta gaaggttctc ctctagaaat ttacgtctat
    55921 gaacagtctt attctttagc ggatcgtcta gaaataacgc taagaaagga ggaagcaaat
    55981 gtttaaaggg gtattgtttg atttagacgg tgtcattacc gatactgctg aattccatta
    56041 tcgtgcttgg cgaaagcttg gtcaggaaat cggcattacg atcgaccaca cattcaacga
    56101 acagctaaaa ggcgtcagcc gagaagactc actctctttg cttttagctt atggcggaaa
    56161 agaacactct ttttcaaagg aagaatttgc agaattagcg aaaagaaaaa acgattatta
    56221 tttagagatg atccagacga tcgaaccaaa agatgtcttc cccggggtcg tgcctttact
    56281 ggattcttta aaagaagaaa aaatcaagat tgctcttgct tctgcaagta aaaacgggcc
    56341 attcctactt gaaaaaatgg gtcttacacc ttactttgat gctattgccg acccggcaga
    56401 agcaacaaac ggaaaacctg cgccagatat cttcctcctt gcagcaaaag ctgtcggact
    56461 aaaagcagaa gaatgtatcg ggatcgaaga cgcgcaagcc ggtatccaag ccatcctctc
    56521 aagtggcgct caaccaattg gcgtgggacg tgctgaagac cttggagagg agatcccgct
    56581 tgtccctgat acgacttttc ttacgatcga ttacttgaaa gaaaagtggc atgaccatgg
    56641 ataatccaga gatctccgtc gtaccagttc cagagactga aataaagaaa atcacattga
    56701 agaacgacta cttagaagtc gttcttctca attacggtgc ccgcctgcac caaatcttcg
    56761 caccagacaa agaaggaaaa tcagaaaatg ttttattgtc ttacgatcgt ttcgaagatg
    56821 ttctaacaga caaaagcttt tttggagcaa ctgtcggacc tgtagccgga aggatccggg
    56881 atgcttcttg gggtgagcat agattggaga aaaactgcgg atcacaccat atccacggtg
    56941 gcacgaaagg ctggtctttc caattttggg aagtagaagt tttcaaaact ccatcatcaa
    57001 taggtgtggt cttttactta aaagatgaat tttctaccta tccaggacca atcactgcta
    57061 cgatcactta ccgtttaaca aaaaacgaat tagagatgac aacctctgct agtagccttg
    57121 ttgaaaccat ctgcaatccg accaaccatg cctacttcaa cctttcagga aatggaacaa
    57181 gagacatcta tgaacatcag ttaacggtct ttttagatgg tgtgcttgaa ttagatcaag
    57241 aaaaactgcc tactggaaat tggacaaaaa aagaaaaact gccaatcgac tttagaaaat
    57301 ccccaacact gcaagagatc cttgcatgtt atccagatgg actagatgat gtatttcttt
    57361 tgcatcatcc taggctttcc aaaacttcct tacaattatt cgagaagcat tctggtcgcc
    57421 aaatgactat agcaacttct aataaaagta tggtattatt ttctacgact ggattcgaag
    57481 ctgatttctc tgtcaatgga aaacagatgc attcaaacta cggattagca atcgaaccgc
    57541 aagaaatccc tgatatcgtt catttcccca aatttggatc gatcaacctc catcctggtc
    57601 aagaacggat cagtcagacg atttatcggt tctctgcaca ataacaagag aaaggtgttt
    57661 ttatcatggc tattaccgta aaagatgtgg cgaaaaaagc cggtgttgcc acctcgaccg
    57721 tctctcgtgt catcaacgat catcctagta tttccgagac aacaaagaag aaagtccgaa
    57781 aaattatgga tgaactaggt tatgttccta acatgactgc ccgcaatcta ggaaaacgca
    57841 tttccagtgc catcggcgta atcttacccc ctcttgattc aaaagagcgg atcggtaacc
    57901 cattttatct tgagatcatg gaagcaatca acgaagaagc gcggaattat gatatgacta
    57961 cagcaatcgc tactgctaaa aattttgaat tgctgttaga gaacgtccag cgtatgcatt
    58021 tacaaaaaca agtagatggt tttattctag tgtattcaga tagtcaagat actgtcattg
    58081 attatttata ccaaaaccac atccctttca ctttgatcgg acagccttat catcatgaga
    58141 acgaaatcgt ttatgtagat aatgataacc agcttctagg taaacaagca acagaatttt
    58201 tgatccagaa tggacataag aatatcctgt ttgtgacaaa cacgactcat gaaagtttgt
    58261 atttcgaacg atatttcggt tatcaaaaag caatgatgat ggctggtctt cctgcgttat
    58321 ccagtgtagt actagagcat ccggaggatt atctgtcctt tgagaaaacg ttgaaagaaa
    58381 acgaagccac agcattggtg gtcattgacg atatcttcgc ccttcgcacg atgcagttgg
    58441 cgcaaatgta tggctatgtc attccagaga cactctccgt cattagcttc aacaactcga
    58501 tcttctcaac attaacacac ccttacctta caagtatcga tatcgatatc tccgaattag
    58561 gacgtgtcgc tatgcaaaag ctgcgcgaat tgatccatga agaattgagc agtggcgtac
    58621 gtttggtcat ccctcatcgc ttgatcaaaa gagagacagt cgttccttta gaaaacccat
    58681 actaaatagc tgactcacta aatacgctga ccatttatcc tatggtcagc tttttatgta
    58741 aaagaagata ctacttctaa cacattgttt atctgtaaaa aagagcgtgg gacaaaagta
    58801 aagaacactt ttgtctcacg ctctaaacac gtataaacgg cggaagcaga agcaactcct
    58861 tcggaaataa gctgaaattc acaaaaattt aaaaagcaat tttcttgagt ttcttcttat
    58921 ttcttggagt taaacgcttc tgtcccagcc tcttttttcc ttccttcaat tttttacacg
    58981 tcgacgattc aataaaaaac cgcctaatat tgtaaagaca ggtgcaagaa tcgagaaaaa
    59041 ggcgaatggc aagtaatgca acgcgctaac tttcatcgtt cccataatga atgtgccgct
    59101 gactccccac ggtacgagag aattgacggt cgcacctgaa tccgctagtg ttcgtgtcaa
    59161 ataggttttt gataagccaa cgtcatcaaa agaacgcttg aatgtttctc ctggaagaat
    59221 gatggacaga tactgttctc caacgatcag attgattccg atacagctca aggcagtaaa
    59281 cccgactaaa cgagaaggtc ggtccatctt ttcttttaat tcttgaacga tggtatcaac
    59341 gatcagatat ttgatcagta acccacctaa tgccaatgca agtaaaatca aactagcaga
    59401 acctaacata ctcatgatcc cgcctcgaga aagcagttca tctagctttg gatcaggtgt
    59461 atttgcgaca taaccattca tcaagatgtc tgctgctttt ccgaccgtca aacttttctc
    59521 atggataaaa gaaagaacga gagcagctgt cgatcccgct agtaatgtag ggatagccgg
    59581 aatttttttg attgcccccc caaataaaat aactagtgga atcaatgtcc aaggagagat
    59641 ccaaaagctc gctttcatgt tttggatcat ttcattgata ctagctagat cggctgaatg
    59701 actgttatgt cctaatatcg tataaaaaat caacgaaagg acgaatgctg ggaaatccgt
    59761 ataacgcata ccagcgatat gttcgaatag attaactcct ccaatacccg ctgccaagtt
    59821 ggtcgtatct gataaaggcg agcagttatt ccctaaaaag gcaccggaaa cgactgcgcc
    59881 tgtagtcatt gcatcattga atccaagtaa atgaccgatc cccaaaaaag caattccaat
    59941 cgtcgaaatc gttgtaaatg aactgccgac agtcactccg acaattgcac aaacaagaaa
    60001 tgctgtcggt aaaaagaaac gcacagaaac aagtttaaat ccataaacca taatcgtagg
    60061 gatggttcca gataaaatcc atgaagcaac taagacacca atcaaaagaa aaatcaggat
    60121 tggaatgatc cctggagtga ttcctttgat gatcccgtca tggatctcat cccatgtgaa
    60181 ctttttaaat ctgccataaa acaacaaaca catgaaagct gcaaggatcg ggatatgtgg
    60241 cgagagctgg aatccgatga tcagtactcc taggagtgcc aacaacacga tcaatacagc
    60301 gatactttct tttaaagaaa tatttttatt catcgtcgat ctcctatttc aaatgaaaag
    60361 gccctgccat gaaaaaacta ttcacttggc aggacctcct actaaatcag cgacaaaacg
    60421 tcggctgaaa gacttatttt tttatttttc ttctaaactt ttttctacct caatccccca
    60481 agaatctttc ttgaagtgat tgatgatcaa tggaataacg aacatgacca ctgtgatagc
    60541 tgctactaat aatgcatcac tcaatgtcgc tgtacctaat gtagcaaata cgacaacgat
    60601 gatagagaag atcagcatgc agctgactac ccaagctaat ccgtttccgt ttttaccaat
    60661 tcggtaagga cgttcgaatt ctggatgttt cttacgcatt ttaagcaatg aaacagcaat
    60721 caaaatgtac acgatacaat aaataacagt tgtagcattt gtaagtgtca agaatacagc
    60781 acttacgtca tccattacac cataaagcaa agcaaataat gaaataacga ttgattgtgt
    60841 tagaacgaca tttctagata cgccgtattt gttttcttta tggaatccga attttggtgg
    60901 aaggaatcct tcacgagcta cttggatgat tgtttttgat ggtccagtaa cccaagctga
    60961 taattgtaaa agcacaccaa taaataccat gaagctgaag atatttccga tcacttctgg
    61021 taagcctagg atttgacagt caatcaagat aggctgcgtg atatttgcta attccatttt
    61081 tccatctggt acgacatttg ctacaagcat cgcattgatg acattcaata aaactaatcc
    61141 gatcaaagcg ataaatacgc cttttgtata attttttgtt gcgtctttca aacgaggcat
    61201 gtaaacagaa ctcatttcga tcccaacaaa aataaatgtg ataccagcta agtatttcaa
    61261 tgaatcaata tgttccaagt cagggaaagc ttttgaccat gaaaagtcac ctagatagcc
    61321 gtttgagact agtccgactt tgaaggctgc caaaacacct aaaacgaaca tgatgactac
    61381 tgggatatat acccctagcc atacaccgat gttcccgccg acttttgcca tatcgaattt
    61441 caagttcaag atcgtgatga tccagtagat aactaaaata caacctaaaa cgaaccagtg
    61501 attattgcca agttctacat taccaaatgt gtttcctaac aatggtccta aagtagaagc
    61561 gaccattacc atacctggga acatttgcac ccataatagc catgcaacga caaatcccca
    61621 tttgctgccc agtgctgttt ttacccataa ctgaggaccg ccttcttgag gaagcatcgt
    61681 ggaaagctca ccggaaacca ttgatatcgg accggcaaaa aacaaaactg caaaaattga
    61741 ataaaaaatc aatgtccaac cgactgcggc taacgtagga atactccgaa ccgttgcaca
    61801 cagtgccatt gtcagaccga taaaggtccc aagacccatt ttacttactt cagatttact
    61861 caccgttgac actctccttg attttttgga taaaataacg gtgtctttga agtagtttca
    61921 gcaataaacg aaacaattca gcgaatattt gaggggattc tttgagttta ttgcttgaag
    61981 ggtttcttca aagacaacct caaaacaaag ggatcgaaga gcttaggtct ccccttgctc
    62041 ttcagatcca aacatgcgtc agaaacagtt agtattcaag ctgttttcta acatgattac
    62101 cttgcttatt ttgcttcgct tgccaataat tggtctgcgt agattttttc caatttttct
    62161 tgaagagctg ctttgatttt ttcagcatat tcttcaaagt gttcttcttt gttcatgtat
    62221 ggtgtcatta cgctggcacg caatacagtt acttttccgg cacggttcca ttcttcatct
    62281 gagaatccta gttggttcac aaattgtaat gggctgttgc catagtctgg gatagcaaag
    62341 tcagtatgtg aagttaagaa ctcattaccg taaatgcttc ctttcacgta tgaagaataa
    62401 tcatatacgt catggttcaa tttattcatt gcaactaagt catcgttgcc tttttctttg
    62461 aatacatagt ctaccatatt gaaatctgga taagttaatg gatgaacttc gatttctttg
    62521 tctcctactt taaatgacaa gtcattcaag aagttgtaga aacgatgtgc accttcgatt
    62581 gatgcaccca ttaatttacc atatcctgtg acattcaaag gtaagacatg gtgtgctgcc
    62641 caaacgctgg ctgctgttgc ccctgctttt gaaccttcca agatataagc cccaagtaat
    62701 gctgggatat ctgcgccttt ttcaaataca tatgtcgcaa agtaagagat aacgtctctc
    62761 atgcggatat ctttgatgac gataccaccg gcagaatatg gaacatagcc cattttatgt
    62821 gggtcaatcg ttacagattc tgcttcttcg attgctttat atgcactgtg tacttcttct
    62881 aagatataat ctttgttttc tgtaaagaca ttgtatttgt aatgaacatc ttttaaatct
    62941 tcaaatggaa tgaagttgtt gtcttcgtct aagaaaatcg cacggccgta tccgccataa
    63001 gcagcatcta cgtgtaagta gaagtaaata ccgtcttttt ctaatacgcg acgcaatgca
    63061 acgattttat cgataccgtc gattgctcct tcttctgttg atcctacaac accgactaca
    63121 cctaggattg gtgttttttc agctgctaga ccacgaacga ttttttcaag ttcgttgatg
    63181 tccatgcgat agttgtggtc aactggcact ggaatcactt ggtctaaacc gataccgatg
    63241 atgtcggcag cttttagcca tgaatagtgt ttagtttgtg gaaccaacca ttttcctaat
    63301 ttttctaaat gttttccgct acgtgctgag tgagctttga tttcgtcgat tttttctggg
    63361 acgctgtcta acagattcat gatttcttct gttgacaagt tcattaattc ccaatcgctt
    63421 tttccagcaa ctagttcagg tgtcacttct ttcattgcaa gcggcaatga tttgatgttg
    63481 cgggcatacc aaagtccttc taagtttgct aaagaaccat cagcaacgat gtggccccag
    63541 ccatctttat agctcattaa ttttgcaaat tccattccta cttcttcttc catttggctt
    63601 gttgcaggag aagattcata ggcaacgtta ttaccattcc atagcatagc aaaattgtac
    63661 gctagtaaag atggcatcaa tgtttcagag ttcatatgac cccagtaacg tccggcatta
    63721 tgccaaggaa cggaatgggt acgcatccgc gctgaaattt ctgatagaac atcctttgtt
    63781 ttattcacag tgtgttcaaa actagcactg cttttttctt ctggcgtaat aataggcatg
    63841 tcttgaggca tgtagttttg acgccagcct aaatgttcat ccaccaattc attcaacaaa
    63901 gctttataga tttggccgtt ctcagctttg tccccaatga atagggcatt taggtttaga
    63961 tctttcgaca atgattcact catagtgaaa ccctcctaaa aaaatattta aattttgtcg
    64021 agccctacat tacacctgtt cttctattct gtaaactaag ttttggcctg atttttaatc
    64081 atattttaat atgtatcaat tatccgaatt gttcacactt ttgaaataat taaaaaaaac
    64141 gagggaattt acaaatgtaa actccctcgc aaagattgta ttaacgacaa ccagcgttct
    64201 attttaggat gggtttcaaa attggaatgt tgtaatagta tttccctttt tcaaggtaaa
    64261 aacttactaa attctaatca attactttgg ccaaaaagta atttttctta ccttttcgaa
    64321 taaccacaaa cttaccatcg aattcatcgg atggatttat gacaaaattt aaatcggtaa
    64381 cgcggtcacc gttaatactt atagctccgt ttgaaacatc ttcacgtgct tgacgtttag
    64441 atggttcaat ttttgtggaa acaagcagtt ccacgatatt ttcaggtgtg cttgaaattt
    64501 caacgttcgg cattttaccg aatccttgcg cgatttcttc cgcatttagt tctttaatat
    64561 ttccagagaa caatgcttgc gttatttttt gcgcttcttt caagtcttct tcactatgca
    64621 caaatcttgt aacttcttct gccaaacggc gttgtgcttc acgtttctca ggttctgtct
    64681 ctactttttt cgctaagtct tcgatttctt cttgagacaa gaaagtaaag aatttcaagt
    64741 atttcactac atcgcgatca tcttgattca accagaattg gtagaactca aatggtgaag
    64801 ttttcttcgg atcaagccaa acggcaccgc ctgcagtttt tccgaatttc gttccgtcag
    64861 ccttcagcat caatgggatc gttaaaccga acgcttctgc ttctggtcct tctaattttc
    64921 ggattaggtc taatccagct gtgatatttc cccattggtc tgctccaccg atttgcaatt
    64981 gcacatcgta tgttttatgc agatgcaaaa agtcgataga ttgcaggatt tggtaagtaa
    65041 actctgtaaa tgagattcct acttccaaac ggctggcaac gatatctttt gctaacatcg
    65101 tgttgatgtt gaagttttta ccgtagtctc tcaaaaattc aagtaaagag atttttgaca
    65161 accagtcgta gttgttcaca aatgtgatat ttgcatcttt accaaacaat tttctcattt
    65221 gattggaaag tgcgtccacg ttatgttgca cttgttccat cgtttgcaac acacgttctg
    65281 ttttgcggcc gcttgggtcg ccgatcgttc ctgttccgcc gccaatcaga atatatggat
    65341 gatggcctgc caattggaat cttttcatca tcataaatgg aatcaaatgt ccgatatgca
    65401 tcgaatcacc agttggatca acgccgcaat aaagtgaaat gctcttttct tcaacgagct
    65461 cgcgaagtct ttcttcgttt gtttgctgat taatggcgtc gcgccaagtt aattcatcaa
    65521 taatattcat tttactgacc tccgtgtagt ttttttatga aagcaggaac ctgctagcat
    65581 atgtaattaa ttatttcttc aggataggat aggaaataaa aaaagtccct tggcatataa
    65641 gccaagggac gaaatctcgc ggtaccaccc aatttgtatg tctagatatc caacatacct
    65701 ctcgaacatt taacgctgtc gcgtggcaat cactgccaaa gactcctgaa atgtaattcg
    65761 ctttaaagca tgtactggtt tgcagcgacc accagctttc tgaaacattg gctttaacaa
    65821 ctacttcgtt tcgatcttcg tcttgttatt attaatatgt gtctatcata gagcgcaact
    65881 ttttctttgt caacagaaaa aggatatttt ttttaaattc ctcatttttt cttttttgaa
    65941 tccgctctaa ttccgaacat tttattttca attattgtta aaagaaataa ctttttctgt
    66001 attttttctg caatttatcg agaagtcact ttactttgcc tcttattctt tcttcgttac
    66061 aataaggaat gggacaagta aaaaaatgaa aaagcaaggg acgaggtata tggaaaaaaa
    66121 gcaaaaaatt attttaggag ccacttctgc tttaactatc gttattttaa ttctaagttt
    66181 gttttttgtc atccgatcat ctacaaaaaa agaaccaatc attcctgaaa aaaaaataac
    66241 agaaaaagca aaagaaccga cagatgataa gcaacaacta gttactcaag caaaaaatct
    66301 ggctcaaagc tacgattatg accaagcgat tgcgttattg gaaaaagata gtaagaacgg
    66361 atctactgaa acacaacagc ttcttcaaac actaaaaaag gagaaagaac aactgatcga
    66421 ctggtctgat cctactcaga tctctcatgt ctttttccac agcttgatcg tggacccgca
    66481 aaaagccttc cactctcaac aggcacaagg atacaaagat tatatggtga ctgttgaaga
    66541 attcaaccgt tcgatcgaac aactttatca aaatgatttt gttttagtta atttgaatga
    66601 tttgatccaa aaagacgaac aaggaaatct ttcctttaac gggcttgcgc tacctgaagg
    66661 aaaaaaacca ttggttcttt cacaagatga tgtcagctat tatgaatata tggataattc
    66721 cggttttcct agccgattgg tcgtatcaaa taacaatgaa atcaaaaatg tctataaaga
    66781 gaaagataaa gaagaaatcg gtgactttga catggttcct ctgatcgatg cctttgtcaa
    66841 gaaacatcct gatttttctt atcgaggcgc aaaaggtacc ttggccctga caggttacaa
    66901 cggagtttta ggttatcgaa catcaaaatc tcaatatgga gacaatgaaa aaacaaaaaa
    66961 agagattaaa gaagctaaaa aagtggcgga acagttgaag aaagacggct ggagctttgc
    67021 ttcccataca tggggtcact tgaatatgac tcaagcttca ctagaagatg taaaaaaaga
    67081 caatgaattg tggcagcaag aagttgcacc tatcctagga aaaacaaata ttctgattta
    67141 tccatttggt gcagacatca gcgactggca gccttattca gcagaaaatc aaaaatttgc
    67201 ttacttgaag agtcaaggtt tcgatatttt ctgtaatgtc gatgcttcta caccagcttg
    67261 gggacaatta ggtacggatt tctatcgaaa tgctcggatc aatatcgatg gcattcgttt
    67321 tcaatctgat ttagacggaa aaaatcctat tcttgatcca ttcatcaatg tccatgatgt
    67381 ctatgacaaa gaagcacgcg aatctgcttg attttacgtc atttatgaac caaaaaagcc
    67441 gaactgacat tttatcgtca gtttcggctt ttttatgctt tatttcttct tcggtgcgat
    67501 tcccttgatc aggacttctg tccattctgc tgtatatgga agcagttttg cgtatatctc
    67561 cggcttagaa attccttcta ccattgcttg aaaatagagg atcaagaact catccgaata
    67621 tttcaaatcc acttttcctt ctttccgccc tcgatggaaa agatcaagca tgatactgaa
    67681 actttcttgc gtatacgcat ccatcgcgtc agaaaattct tttttttctt tttttgtata
    67741 gtatgtcatc aaatcgatat aaaattgttt gttcactcga ttgagataac ggattttgtt
    67801 ttcactcatg gcaatcagtg tttcttcaaa tggaagattt tccgcaatca acgctttcgc
    67861 ttcttgccct aaatcattca taaatgcaaa aaatacttca taaatcagcc cttccttgct
    67921 gccaaaatat ttaaaaatcg tcgctttact tacctgagcg ttctcagcta ccttatccat
    67981 tgtcactcca gcggttccta tgtctgtgtt catcaagtca aaagctgctt gtaaaatctc
    68041 tttctttttc tcttgtgctc tcttttcaaa accgttcatt tgtagagcct cccgtaattt
    68101 taaactttta taatatatat agttcaaatt tattctgagg tttattataa ctatctattg
    68161 agaaagtatc aagctagcaa ttccttgttt atgaattcat tgacagaaat ttataaaaag
    68221 aatattatgt actaaaataa taaaaaaagt tttataaaaa ggtataaaac ctttttatta
    68281 aactatttaa tcttgtttag tatatatttt tagaaaaagg agtggggttt ttatggcaga
    68341 aatcgtcaaa gtcacacatt tgaaaaagag ctttggtcgt ttcgaagctt taaaagatgt
    68401 ctctttcacc gtacattcag gtgaagtcgt tggatttatc ggaccaaatg gttctggaaa
    68461 atccacgacg attcggacac ttttagggat tataaaaaaa gacggcggaa cggcaacgat
    68521 ttttgggcaa gatgtatggg aagatagttt atctatccat gaacgtcttt cttatgttcc
    68581 aggcgatatc tctttgtggg gaaatttgac tggaggagcg atcatcgatc tcttcatgaa
    68641 gcttcatgga aaagggagtg ctcaaaaaaa agatgaactg attcaacgtt tctctcttga
    68701 tcctaagaaa aaagcaaaaa actattcaaa aggaaatcgc caaaaagtgg gcttgattgc
    68761 tgctttggct gttgattcgg atctctattt atttgatgag cctacttctg gtttagatcc
    68821 tttgatggaa acgattttcc aagaagaagt tgaaaaattg aaagaacagg gcaaatccat
    68881 cctactttct tctcatattc tcagtgaagt cgagcgacta gcggataaag tcgtgatcat
    68941 acgcgaagga acactcgatg aagaaggaac actcgatgaa ttgcgtcatt tgactcgttc
    69001 gaccatcact atagaaacag aagcagagaa tagtcactta gcacaattga acggtgtcca
    69061 tgactttgtg caaaaaggtc acctcgctca atttgctgct gataacgaag ctttcgatgt
    69121 gattttagct gaagcgtcca aattaggtgt gaaaaaattt gaatctattc caccgactct
    69181 tgaggattta ttcatgagac attatgaagg atgaggagga agcgaaatga ctgataaatt
    69241 ttcacgctgg tccacccttt tttctcaaaa ccttagccgt gactggaaaa agatcctgat
    69301 atggctagtc ggtgtcactg ctttttctgg tggttttgtc cctgcgtttg aagaattgac
    69361 ttccggacaa ggattagctg gattatacga aaccttgcaa aacccggcaa tgattgcaat
    69421 ggtcggacca actccagctt cgaatgctgc tgagtatact ttaggagcga tgtatgcaaa
    69481 tgaaatgttg cttttttgca gtttgtttgc tgctgtgatc tctgttttac acgtggtgag
    69541 ccaaacgaga aaaaaagaag aacttggtct gattgaactt attcgttcct ttcgagtcgg
    69601 acgtcaagca aactctttag ctgtcatcgc tgaaagtatt ctgatcaatt tgcttttagc
    69661 aatatcgatc agctgtacga tgattttttt ccaagcggat tcgatcactg cagaaggtgc
    69721 ttggcttttt gggctatctg taggtagtat ggggattttg gggagtgccg ttgcactgtt
    69781 tgctgcacaa ctgatgccaa gttcagccag ttcgaatggt ctgtctttag cgtttttagg
    69841 tggactttac cttctacgag caataacaga tgtagctgat tcctcccttt cgatgtggaa
    69901 tcctttaggc tggtcttatt tgacctatcc atttacaact aacaactgga ttcctttgct
    69961 ttatttgttt ttgttcagtc taatcttgat aatcagttca tttgttttag aggaacatcg
    70021 agatttgaac accggctata tccccgaacg tgaaggaaaa ccgtatgcta aacgttctct
    70081 tttatccttg cgtggtttat tattctatct aaataaaggg atgacaatca gttggcttat
    70141 cacttttggt ttgatggggg cggcatacgg ctctatctac gggaatatgc aacagttttt
    70201 agaaagtaac gacttaatga aacagatgtt tatccaatct ggcgtctcaa ttgaaaaaaa
    70261 ctttacaagc acgatcatgg tagtcttgat ttgtctagct gctattttac caattgctag
    70321 catcaatcgt ttatttacag aagaaaccca cggacgtatg aatcagctgt tcgcaacaaa
    70381 aatttctagg aaccaacttt attggaccaa tatgttacta gctattctat ttgctatatt
    70441 ggcaatcctg attagttctg gtgcactagg gctttctgct ttggcttcga tgaaggatgc
    70501 gaaagacatg gatctattga tgtttcttaa agccgggttc aatttcctgc ctgccgtttt
    70561 agtgtttatc ggaattagtg gctttctatt cggatggctt cctcgaatcg gtaaacttgc
    70621 ttatatctac ttagcttact cctttgcact caattacttt ggcggaattt tggatttacc
    70681 agaatggttt tccaaaacag ctgtccctag ctgggttcca cggatgccaa acgattcttt
    70741 tgatctttcc gtgttcctta cgttatcatg tatcagcctt gcactgttcg tccttggttc
    70801 tattggttat aggcgaagag acttactaga aggataataa aaaagcatgt acaatttcat
    70861 gctagcctcc aaatctgggt caaaaatcca acatttggag gtcatttttt tatttacaag
    70921 tcttctaact gctctttatc aatgatccag acttctcgat tctttctttt tacataacca
    70981 ttctcctcta ataatttaaa ttttctagat aaagtttcgg gggtcgtacc gataaatgca
    71041 gcaagttctt tcattttcat tggcaggaaa aagtgatcct tccctgtcgc tttagctaag
    71101 tcaagcagat agacagcgac tcgttcttct actttttcca tcatcaaaaa agttgtctgc
    71161 tgctgtactt ttgttaattt ctcaacgttg attgctaaaa gtttcagact aagggcggga
    71221 taatgcagta agagttccga gaaatctttt tgtctcaata tgcaaatttc cgttttttct
    71281 agtgcttcgc caaataaaga ctcatttgga acgcctagca actggctctc tccctcatat
    71341 ccgcccggct ctattactcg taaaagctgt tcctttccgc tagcagataa ttgatacact
    71401 ttcatactgc cggaggccac gatcactaat tgaggttctc cattcggcgc aagaatctgt
    71461 tctccttttt ccacatagtg atgtttgaca agtgcgtgta ctttttcttg atcttgctgt
    71521 actaagtgat tgaacaaagg aacaaatgaa acacataaat gatcatgact cataatctct
    71581 cctccttcta aacagctatt tctaataaag aaacataact tcccttattc caactgataa
    71641 ttttctttta tcatagcata aacgtcaagc gaaccagata ccagcaaata gagtggattt
    71701 ctttttgtcc cttgctttat tttccttctt ttgagacctt aagtaattga ttcctatcaa
    71761 ttttttaaat atttactttt tgaataatca aaaacaaacc ttcactcgca agccgagagt
    71821 aaggtttgtt tttcgcattg cttatttcgt gttgtctatt gaaatttttc cgcacctagc
    71881 ttttgatata gtggtgctag ttcttgtaag gtttcagcgg ttatttgctc aacgtgttcg
    71941 atttcttgcg gatagaagaa tagtttaccc atttgaaagg ttcggtctct catcgctttt
    72001 ttcaactctt cttgtttctt tgtatcggac aaatagtcag acaaagctaa gtggtcgtca
    72061 agttcatgtt ctggttgcgg ccatatgtaa taatccttga tatcgactgt tttgctccac
    72121 tctttcagta tcgcaagcaa ctggttatac gctgcaatgc taccatatcg ttcttcgctt
    72181 ttataatgtt ggtacatcaa atagatttgg tattgttttt gattcaacaa aactgctaga
    72241 caggcattct cgtcttgacg agattcgctt cggtacgcgc tccaaaaatg actgcgtaaa
    72301 ttccagccat tcgtccagct ttcgatttta ggtttgctca tgccgtacat atcaggcaaa
    72361 agtgcagctg tctggagctg aatctctttc catttttgcc agtgttcttt atattctttc
    72421 ttgatttgtt caatcttatc tgttggatgg ctctctttga gctgtttgaa tgcgtagatt
    72481 ggtcgatcaa acaactgata atctgatttt ccaagttcca ttgtttcgcc tctttccgtt
    72541 atcttttgta ttctacctga attttgcgat atggacaaat agaggttgtg aaaaagctgt
    72601 tctgcatcaa gtcataagaa cagccaaaca aaaaactgcg atgagcatca ccgcagtttt
    72661 attgaactta aggttgattg atcacatcta aaagcgttga aaataaaatg gcactagaag
    72721 cagctcctgg gtcgatatgt ccgattgcac gctctcctag ataggaagct cgtccttttt
    72781 tagctaccaa gactttggtg tgttcttttg cctggtcaat gatttctttt gttaaattcc
    72841 ctgccttcaa tgcctctgtg actggcagcc aaacatctaa catcgtttta tcgtcagctt
    72901 ctgcctttcc tcggctttga atacccgctg ttccctgctc gatcacttcg cctaattttt
    72961 cttgagaatc aatagaatcg acctcttttg tcgctttcat catgttcatg aatgcagatc
    73021 cgtataacgg accagaagcc ccaccgactt tcgatatcat cgccatagag aatactttga
    73081 atgtatcgct gattgtttca ggatgatcgg cttgaaaagc ttcttcataa gctgaaaccc
    73141 ctcttcccat gttatttcca tggtctccat cgccaatcgg ggtatctaga tcactgagat
    73201 attgtttgtt ctgattgatt gcctctgcaa attgcgtgag ccattcttgg atttcttgaa
    73261 cggttagttt catattatca cccttttatc ttgagatttt ttaccatgaa atcgtctgta
    73321 cattgctttc taaagaatct ttccattgtg tctccgtcaa gtcgatcagt gttagagaaa
    73381 gaccttgcat atctagtgag gtcataaaat taccgacttt tcggaaaact acattgacgc
    73441 ctctttcttc caacagagct aaaacatcat tcatgaacac gaactgttcc atcaaaggcg
    73501 tcccgcccat tccgttgact agtacacctg cttcttttgg taaattcgag taatcatcta
    73561 aaatcttagt aacaagttcc tttgccagta ctttagaagg ctgcatcttt tctcgacgat
    73621 agcctggctc accgtggata ccaacaccat actcgatctc atcttctcct agttcgaatc
    73681 ctggtttccc tacttctggt acagttgctg ctcgaagcgc tagaccgatc gtcttagttg
    73741 cctgtacgac cttttctccc agttctttca actcagctag ggaagcaccg tttcttgctg
    73801 catcgcccac gattttgtgt acaaggacag tacctgcaac tccgcgtttt ccagcagtat
    73861 acgtactatt ttcaacggcg atatcatcat ctacgatcac actttctact tcaatatcgt
    73921 ccatagcagc taattccttt gccatatcga agttcaatgc atcccctgta taattcttaa
    73981 cgatcagcaa aactcctttt ccactatcgg cttccttaat agccgtctga atctgatctg
    74041 gagttggaga agtaaacaca tcaccaagca ccgctgcact taacatccct tcccctacaa
    74101 acccggcatg ggatggttca tgtccgcttc ctccaccaga aaccaaacca acttgttccg
    74161 ctttctgatt cttggctaca acacgggaag attctacacg atgaacaagt tctggatagc
    74221 tttttactaa tccttccagc atttcttcga caatattgct tggatcattc atgatttttt
    74281 tcaatttatt cccatccttt ctttccggca ttttgtgctt ctgttaagat ttgctgagta
    74341 tcatctgtta taccggcagt gatggctgct gcaaaagctc cttccactaa aggcgcatcc
    74401 accagatgat aacgttgctg ctgctcttct tccaacatgt cttttgccag ttccgagttc
    74461 aataccgcgc taccgatatc cgcaaaaaca aaataactag ctgcatcgct tgattcattg
    74521 actgcttcta cgattttcat cgggtctgat ccgatctcgc catttattcc gccgagagaa
    74581 aaaatttgca cctcttcgga tttttgcatc tgctcaatca tttctttaat accatctgtt
    74641 actttttgac tatgagaaat aagcaaaata ctttttttca caagaatctt cctttctttt
    74701 acatagttgc taacgattgg tttcgctttc attaatgaac aattcaagta tataataaat
    74761 ttctaatttt gggaaaatat gtgtagtgct tcttgaagtt tgttatactt taattaaaag
    74821 agaggagtga tcgaatgatt acaacaacaa cgaacagtgt agagggaaaa gccgtagtag
    74881 cttataaagg gatcgttttt ggtgaggtca ttactgggat ccatgcattt aaagacttgg
    74941 aggcggggtt gcgaaatatc tttggcggcc gctcaaaaag ctatgaaaac gaactaatgg
    75001 gtgcaagaga agaagcactt gccgaaatgg ccgaacgtgc aaaagcatta ggagctgatg
    75061 cgatcattgg cgtaaaaatg gactatgaag tattaggcag cgacaatggc atgctgatgg
    75121 tcacatgtag tggaacagct gtctccacga gataagtagg ggacatctgt tttaataact
    75181 aaagagagat gggacatgta gtggcactca agaattagat ttttcagtct aacttcgagg
    75241 tactctacct tcccatcctc tcttttttat ttctttttgc ggatgattcc gtaagctgct
    75301 gcgactaaca cacccgcccc tgctaaggaa taactgacag aagctgtttt ttcatttgtt
    75361 tttggcaaag tctgacttgt tgatttggat ggctctgtcg tttgctgaac tgtttctgtc
    75421 gtgcttccag aggtcactga tttttctcct gccgaatgca aaatatcttt tattcgttgg
    75481 aaactagctg ctaagtcagc tttttttgct tcaaaatcat tagcaactgt ttgtgcttcg
    75541 ctgatctttc cgtggattgc ttgactggcc gctgtgatat ccgcttgagt ttgacttagc
    75601 tttccagaag ctgtttgagc aacctgattt aattgctgat tgaattcttt tgcttgttgg
    75661 atcttcccgt caagatctgt ttggacagct tccgcttttg ctttcgcttc ggcaagcttt
    75721 ttctcaagtt gtgcacggtc atttcccact ttatttttaa gatcagctaa atcttgatcg
    75781 attgctgctt ggtcttcttt caatttgttt tttgcagctt ctaatgcttc ttcgagttct
    75841 tttcttttat tttccaagtc ttgcaaatga tcgatttggt cagaagaggt agaactattt
    75901 attgatgtat cttctgaaga tgaaatcgtt tctcctgaat tatctgtcgg tacattggaa
    75961 gtcatttctg tttccgaggc accgttttca gcaccagaag agcttatggt tgttgaaggt
    76021 tctgtttgag caggttcaga agtttccgca aaagctgtct gtcccaataa gaaaatactg
    76081 gaaacagcaa ttggccagat taacggcttc attctttttt tcatcacttt tcccatcctt
    76141 actacttttt aactaatttc ttattataag caaaaatgtt tggaagaacc ataaacacaa
    76201 caggctgttt gtctaaaaaa cggtgcatct tttatttttt tgtacgttcc gggcttttcc
    76261 atgtcccgct tccataacct aaaatcgttt tgactgctgg aatgaaagtc gtcacgatcg
    76321 ttatcgcgtt cactatccag aacaaaagca tatatagtgg tgcgaaaaga aggtatttca
    76381 attttcttcg tcgatcatct acaatcagcg aagctagcaa ctggaaaaat cctgcgacca
    76441 tttcaaagca gatgaacaca aaactgaatg taaaagtaat ataaatctgt tcgtagtttc
    76501 cttgatatac ataatgcccg attaatccag caaaaagaac tacggaaata caaaagaata
    76561 ttgaccagac aatactcaat gtttgatcaa tgaagatgat cgttcttcca atatgtttaa
    76621 aaggatggag catcactttt ttgaaattcg tcagccagac ttctgttcca ccttttgccc
    76681 aacgttttct gtgtcgatat agcatcttca acgtcacagg tacttccatg aaaaagataa
    76741 tctcaggagc aaaaacagat aaccagtcat ttaactgatg atcccaagca atactgatgt
    76801 cttctgtcgc tcgatcttgt ctgaatccgc ccacatcgat caaggcttct tttcgataca
    76861 tcgtatttgc tccactgtac gcataaagac caccgaaaac agctgactgt gttcgtttaa
    76921 tgatgcccac gatacttgag aattcaaccg tttgagattt tgcaatcaat ttggtacgat
    76981 tttggacatc catatttgca gtgaccgcag caatatgtct tgcaccaggg cgaatgaaat
    77041 aattcacata cctaatcagt gcatctggct ccggtaccgt gtctgcatca ttgcttaaaa
    77101 tcaatttccc ttttgcaaag gcaagtccga tattaaacgc gtgggctttt cctttatttt
    77161 tttcgatccg aaccacacga agattagcgt attttttcat cagtctagct aatatttctg
    77221 gtgtttggtc cgttgaacca tcgtctgtca ctaatacctc atagttgtga taattcaatt
    77281 tcgtcatcaa atactcgatt gtatattcga tcacaatttc ttcattatgg gctggcacca
    77341 tgatcgtgat gaacggttcg acactcaagg gaacatctac ccattctttt tgcttatgtt
    77401 tgtataaaaa cacataacac cagacaccaa taaaccatac aaatccgcct aaaatcggat
    77461 aagaaacgag aaaaaaatac ataatagaca aacaagtatc taagaataaa ttacctgtat
    77521 gggtgattga gatcatttca gttccacccc attttcttta tacaaatctg caatgaatgt
    77581 cgtatctaga tttttctctt cggagacaga ataaaaacgg accgtttctc tctcttcttt
    77641 tgttccaaaa cgttccgtat acacttcttc aagtaattct tgtctttttt tcaatttttc
    77701 atcttcatat tcaaaagatt tatttacttt tttgtataga tttcgattgt tccacctagt
    77761 caatacaaat gaggtaatca ggaaactgaa aaaaatcaat acaaaaaagc cgattaagaa
    77821 atacagcatt ttcttttctg ataaaaaagc gtacaaggaa aaatccttgg ctctttctgg
    77881 tctcgttaat gggaaaaaga cccatataaa aggaagaaca acgatcatcc atcctaaaag
    77941 agccactaac gtttgccaaa tctttaacca gtaattacct tttgaaaaat acttatcttt
    78001 caccaaaatt gatgcaactt cttctcttgt tacttttttc atatcctcac ctcacgtttt
    78061 tttgttacga cgtaggagtt taccatacat ttcatttctt ttcacataaa gtgttcctaa
    78121 atttttccta agaaaaagaa caaaacattt ctcatcagca aatgaaaaat attttgttct
    78181 ttttatcagt tgttcttttt attttttatc tcttaattat gttgctcttt ccaatacgac
    78241 aatgcttttc attcctctag atatcgccgt gtacatttgt ctgcgtcttc tttgctcatc
    78301 tccatcgttt tcaaatggat ataagattac atgatcaaat tccagtcctt ttgctagact
    78361 caaaggaatg atttggcagt tttctaatcc atatgaattt tttttaatcg attcttgtag
    78421 cgtttgggtt tcctcttctg tttgggtgat aactgccgct ttttctcctt ttagagaaac
    78481 caaaatctca gctagtattt tcaacaattc ttcagaggat cgaaaagagc ggtattcggg
    78541 ttcttttcct tgcggtcgga tcgatacgat gtcgatcttc tcttgatcca cagcataggt
    78601 tttgaaaagc tctgtgattg ctccgctaga acggtaacta tttctaagat cataccgatg
    78661 gatcggcaga tggtagtcgt cgaaacaacg cataatatca gcaaaagtag tggaagaatt
    78721 aaagattgcc tgattctcgt cacctactaa agtaaagtga gtttttggaa ataattcgat
    78781 caatagacct aattgtgcca gggtataatc ttgtacttca tcaatcaata gatagcgaaa
    78841 tgctggtaca tttacctttt caacaagtaa atgacgaata gctaatataa tgactgcttc
    78901 atcaacagta cgtgtgggtt gccaagcata agctgagcca tatcgttttt cataaattct
    78961 ttcaaacaac tgatgctcat ccacccatgc catttcttcg atttgtctgg ttatttttcg
    79021 atattttttt tgtaaaagtt tccttgcata agctacaata ctttgttccg aatcatcaga
    79081 aatcaattta ccgaataatt ccaactgcct atcttctgtc aacgagagta cctgattctg
    79141 cacagcagga ctttttgctt gtttcaaaag atgattcttc cattcgctca tcagtgcctt
    79201 tttcgttgct tgaagcctat cgatcaattt aggatgagca ggaactttct catatatttt
    79261 ttcgatcgtt tttttagaaa ggactgtttt tccattttta gtaagtccac ggataaaatt
    79321 cggatgatct aaaaacaaag gatctgattg ttttagatta tcgataaact ttttgctacg
    79381 caaacgttct gtctgctccg atacattttc tcccgtgata cgtttgaaat aagcctcttc
    79441 accttctatt tcctctgctg aaagctgtga aaccagctgt atgatggtta gattcagtgg
    79501 atttctttca cctaatgatg gtaggacatt cgaaatatag tcgataaacc gatgattagg
    79561 tgatagaatc agcaagtcat cggatgtcat cgtatctcga tataaataga gcagatacgc
    79621 aatacgctgc atgatagcag aggttttacc acttcctgct acgccattta ccaagatatt
    79681 ttgacttttc acatcccgaa tgattgtgtt ttgttccgat tggatcgtag cagtgatagc
    79741 cttcatttca ttggtctcat cttggcctaa gacttctaat aatacgtcat cttgaatagc
    79801 tacagacgta tcaaaaaact tgaccaaacg atctctttcc aaaagaaatt gtcgtctttc
    79861 tttaataacc gtatcgattt tattttgacg aaccgtataa gaagatggac caatcatgtt
    79921 attgtaaaaa agttcggcaa ttggtgaacg ccaatcataa acaagatttt catctgcatc
    79981 atctgtgaaa tttgctgtac cgatataaaa ggattctttt ggctcattat ccagaaagtc
    80041 tacaacgact tttccaaagt agggactttt caataaacgt tcgatctttg ctagctgatt
    80101 ttctgcgttt ttctgtttga tattcatctg atcgatttct ctatttttca tttcaatcat
    80161 cgaaaaagta tccaggttat ctaagtaact gtcaaaattc aatcgaagct cgccagccat
    80221 ttctttcaac gactggtttc cttctatttt tgccgtatcc atcgattccc gcagttcgtt
    80281 ttttttatca attagctttt gatacacgtt cttcagatat gcttcttcta actgtttttg
    80341 tgtgttgacc atacacattc tcctcttttt ttaaagtggt ggaaccgatt agtttacctc
    80401 ttttaagagt cgaatgcaag ctttttaacg agtatcattt gttaggatat atcagttctt
    80461 caggtcggac agtttgatat aaagaaaatg caccatcaag gttttttacg tggtagccag
    80521 actgcttcaa gattctttcc gctagatagc tacgtaatcc gctatgacag ctgacgatat
    80581 attcttgttg gctgtctaat tcatttaatc ggtcccgaag ttcattcaaa gggatatgtt
    80641 tggcttcctt gaatttgccc ttttccaatt cttctgctgt tcgcacatct aataaaattt
    80701 ttccttttgc tagttctgtc ggcaattcat gccattgtac ggtttcacta agcccttctg
    80761 caatgttcat tgctgcatat cctagcatgt ttactggatc tttggctgag ccaaatggcg
    80821 gtgcatacgt caattctaat tccggtaaat cgaagatcgt caaatgccct ttgattgctg
    80881 ttgctaaaat atcgatccgt ttatccacac cttttgcccc aacaccttgt gcaccataaa
    80941 tctcgccagt ctctggatgg aagatcaact tcagtaaaat atctgttgct tctggataat
    81001 agcttgcatg atcttttcct gatacatgaa tgacttcaaa agacagttcg ttttctttgg
    81061 ctgttctttc acttaaaccg gtggatgcgg cagtcattcc aaacgttcgt ataattgctg
    81121 ttccaatacc gccttgattt cttcgagaaa ttccggaaat cgtgtccgca acttgtctac
    81181 cttgacgatt ggctggtgaa gcaagagaaa taagtgcatc ttttccagtg atttgctgtt
    81241 ttacaacgat agcatccccc accgcataaa tatcaggaat attcgtttga taacgttcgt
    81301 ctactaggat acccccgcgt atgcctaatt cgattccagc ggtcactgct agctggttat
    81361 caggacgaac accaatggat aaaataacta aatcagcagg gatggtacgc ccatcatcca
    81421 gtcgcaatcg tttcccgtgg tcttcaaatc cagcgacagc atgagaagta atcacttcta
    81481 ctccttgatg agacaattct ttttctataa aagctgccat ttcttcatcc agtgttggaa
    81541 gaatatgtgg tgcttgttcg atcaccatga cttctaaacc tcttcttttt aggttttctg
    81601 ccatttccaa tccgatgaat cctgcaccaa cgatcacggc acgctttggc tgtttttcta
    81661 atgcatgcat cactttatcg atatctggta catttctaat agaaaaaaca ttgtcggctt
    81721 ctgttatccc tggaatcgat ggaacaactg gttttgcacc aggagataaa accaatgcat
    81781 cgtactgttc aatgtgtttt tgaccctcat gtacgacttc taccgttttg ttttcgggaa
    81841 agatggctgt cacttcatga tttggacgca catctaaaca aaaacgagcg gataatgatt
    81901 ctggcgtttg gacaagaaga ttttcccgtt cactgatttc tcccgaaaga taataaggca
    81961 agccgcaatt tgcaaaagaa acatacggtc ctttttcaaa aacaacgatt tctgcatctt
    82021 ccattaatcg gcgaagccgt gtagcagcag acattccacc tgctacacct ccgacaataa
    82081 cgattttcat cttatttccc tcctactgtt cgatcaaacc attgattcat gccaccacgt
    82141 acattcacta catcataacc agatttcttt aattctttag ctgcttgttt actcctcatc
    82201 cctgattgac aaatcacata gacggtcttt tctttgtctc catcatatct gtttatactt
    82261 tgtaatggaa catttttagc tccttttata tgcccgcccc ggtattctgc aggtgttcta
    82321 acatcaagta acgctggatt ttccaaaagc ttttccttta attctgggac tgttatcgat
    82381 tttattgatt gaaatagcaa attcattttc tgcacctcat ttacattttt ataaatacct
    82441 catggggtat attaaacagg agctttatta atatgtcaac cagaatgact cttcattttt
    82501 ttcactactt tttatatttg cataaaatac cgataagggg tattatctaa ttataaaaat
    82561 agaggagaat gtgttatgga gattgataat aaaaatatcc tgaaccgttt gaaacgtaca
    82621 gagggacaaa ttcgtggtat ccaaaaaatg atcgaagacg aaaaagaatg tatggatgtc
    82681 atcactcaat taagcgctgt tcgttctagt attgatcgcg taatgggcat gatcgttgca
    82741 gataatctga aaaattgctt tgagaaacct gatagtaatc cagaagaaca agcggctaaa
    82801 ctagaacaag cgatcaagat gattattaaa aagtaaagga atgatttcaa tgaaagtcgt
    82861 tttccatatt gatgaattag aaaaatggtc agaaacaggg aaaaacgtaa aaaacctgat
    82921 aaaagcttct ccagaaacga cgattgtcgt atctgtaaat ggcatcgcga ttaccggtta
    82981 tctagactct gccaatgcag aattcttaga tttgcaagga gtcgtttttc acgcttgcgc
    83041 caatgctatg cgtgctaatc atatttcaga aagttcttta cctgaacaag taatcgttgt
    83101 accagcaggt gtccttgatt tagttgaact gcaatcccaa ggttatgctt atatcaagcc
    83161 ttagtcagta gaggttgcga cagaagtgat cagcttcaag aaatttcggc ttatttttcg
    83221 aagaagctac ttctggaaaa ccgtgaatca aaggttgtga aaacgctgtc ctgcatcaag
    83281 taataagaac agccaaacaa aaatagcttc tcatattttt cgtttggttg ggcttattac
    83341 cgcagatgca agcttttgaa caccgtttaa ggaagaggtt gtgaaatcag cggtttgacc
    83401 taagtattag agaaaaaaac gggaaaatag ctcctcatat tttgccgttt tttgagctaa
    83461 taccgaaggt cagctgattg aacaccgttt aaggaagaga ttgtgaaaaa gtcgcttagt
    83521 ttcgagtatt aagaaaaatt ttgtgaaaat ggatttctac atttttgcat aaatttggct
    83581 taataccgag aaactggctt ttgaataccg tttaaggaag aggttgtaaa atcagcggtt
    83641 tgacctgagt attagagaaa caaacggaaa aatagctgct catattttgc cgttttttga
    83701 gctaataccg aaggtcagct gattgaacac cgtttaccaa gaggttgtga gcctaccatt
    83761 taactccgaa tcacaagaaa taatttcaaa aacaacttct cctgtttttg gttcggttgg
    83821 cttattatcg agaagtagct actgggagtc tatttatcaa aaaaaggaat gcgacatagg
    83881 tcacacccct tttttatttt ctttgaaaca tctttcggta ctcgacagca tacaagacaa
    83941 aagattgtaa aagaccgtaa gtgatgacgg caaaaatgac tctcacccac agcgttggta
    84001 attctgggaa aagcagcaaa aggatcatgc caacatagat gacagcagtc gctactttgc
    84061 cataccactt cgctccactt aatttgatat ttttagatag cccgattaat ccagctacaa
    84121 acataaagcc ttcttttatc aagaatagac caaacaacag ccaaagccac ggtcgatacc
    84181 atgccataga caaaatcaga aaaagttgtg tcaatttatc tgcaaacgga tcaagcacct
    84241 tccctaagtc tgttacctga ttatatctcc gagcaatgac cccgtctaga taatcagaca
    84301 aacctgagac aacaatgacc gctcctgcta tataaaatga ctgtctcagc acaaaataaa
    84361 gataaatcgg cagcaaaaaa atacggaata tcgataaaag attcggaatc gtttgtattt
    84421 ctttacgcca gtctgtgctt aatttcattt tatcgcccta cctcctcagc actcttttct
    84481 ttttatttta gcttacacgg ggaataaaac caatgatttc actgttttta tttttcttta
    84541 cagacactga tattatgagc taatttgaga taatcacttg ctgttttcat cgtttactct
    84601 tctttcttcc tgtcgtttgc gcatttcttt tactagtact ttatgagctt tttttgatcc
    84661 tcgctctagg tcacgctgcc gtttacgtgt tttataatcg ataaacagac tgtctaaatc
    84721 gtaacctgtc gggtacagat cttctgctga acgcaccaga cgaacacgct gacgaggcac
    84781 gtggattatt tttttgtcta aatatacatc aatcgtatct tcacctatat cttcataaac
    84841 taacgcttct ttttggtatt cattgacaaa tatccgatca ccttttgcaa agagctgacg
    84901 ttctttttta ttctccttcc tatttgtaac tgctgtctta ggaagaaatt cttttttctg
    84961 tgtccgatag gctttttccg ccaagtaacg ctctgcttga tggatcaatt tcatcgacat
    85021 atccatttta tgagcaatcc acaaagcttg gctttctcct gtttcttcca acccgcaact
    85081 gatatttagg acgaagtgct tcccgatcga aagccatagc agccggcaca aaatcttcat
    85141 gatctccggc gaatttcttg atttctccat aatgggtcgt ggcaatgatc aatgcccctt
    85201 gctcatacat agattccatg attgcgatcg ctagtgcagc cccttcattt ggctctgttc
    85261 cactgccaat ctcatctaaa agtaccaacg tattcctttt tatctttttc aaaatagcag
    85321 cgatgttttg catatgacca gaaaatgtac tcaacgcatt ttctaaattt tggtggtcac
    85381 cgacatcgac gaaaatctca tcaaagacag caagctctgt cccttctttt gccggaactt
    85441 gcataccgaa catcgccatc aaagtcaata aaccgactgt cttcaacacg actgttttgc
    85501 ctccggcatt tgctccggtg ataatcaagc ctcgatagtc tttaccgatt tcaacatcca
    85561 atggtaccgc atgctcaggt aaaaatggat gtctgccttg cttgataatg atatgttccg
    85621 atttattgat tctaggtgtg cttccattga tttctcggct aaattttgcc cgagcaaaga
    85681 tgatatctaa caccgtgatc gtttcgatca ataaatcgat cacttcttcg ttttctgcga
    85741 tagcaccagt caatgccgcc aggacttgat attcttcact gatttcttca gcttttaaca
    85801 actgatagtg ttcattcaat ttagaaatca cagttggttc aataaaaacc gtcgttcttt
    85861 tatttgattc atcgataatc gttccatcta ttttattttt atagctggct ttgataggaa
    85921 tcgtatagta ttcgcctttt tgaacaatca ttgcttcttg gatcatttct ttgtttttcg
    85981 gatgacgcaa gaatttcagt aattttgact ggatttcttt ttcgattagt tgtaattgtt
    86041 tgcgtacttt acgcaaatta cgtgacgcgt cgtcactgac tttattattt tttattttct
    86101 ggtcaatcaa ctcttctaca tttatcaaat caggaagatg tttgctataa gcaaacaaca
    86161 agggtgtctg gtattgattc ttatcaaaaa actttgtgat catccgactg cttctaagaa
    86221 aatccgcata ttcgatcaaa tcggttggct gcagaatcaa cccttttttg acttgttctg
    86281 tcagtgcatc gatcctcggc aaccccataa atggaacatg ctgactgctt tctaagatca
    86341 agcgtgcttc tcttgtttct tcttgacgat ccaagacagt ttgtaggttt gtcgagaccg
    86401 tcatatcgct gattcgtttt ttgctatagt ttccaattgc tcttgcttgg atttcctttt
    86461 tgatccgatc aaattgtaat tgactaatca tttcgttgtc catattctct ccttttcttg
    86521 aagagatacc tgtcccaaaa taaataaggg cctagagata aataaaagga tagaacacag
    86581 cttaaaaaag tcatgtccta tccttattag aatacaaaga tattgttttc ctgacaggta
    86641 ccgtttcata agcacaccaa ataaactttg tttattggct attcgactta ctgattagat
    86701 accagctaca ctcacaaaac ataccccatt cttctaggtc ttatttattt tccacttaac
    86761 tatagcaaga cacattttgg ttgtcaaact ttagtatgtt ttatagattt acaccattaa
    86821 tgaatagaca cctaccgcga taattgctcc gatcattgga cctgcgattg gtacccatga
    86881 atatgcccaa tctgaagttc ctttattagc tattggcaat accgcatgtg ctaatcgagg
    86941 accaaagtcc cgagcagggt tgattgcata tcctgttggc cctcctaatg aaagaccgat
    87001 ggctaagatc aatccaccta cagcgaatac gttcgttcca ggtgcaaatt cgttttgtcc
    87061 aaaagctagc aacccaagaa ctaatacaaa tgtaccaatt aattctgtga tcacatttgc
    87121 tggataattc cgtatagcag gacctgttgc aaacgttcct aaaatcgcgc tttcatcttt
    87181 cgttgcattc caatgtggca aataagaaag ccaaacaaga atggcccctg caaaagctcc
    87241 taaaacttgc gcaatgatga aaggaacgac aagattccaa ctaattgccc ctgtcatcgc
    87301 catagctaga gagactgcag gattcaaatg agctgggccc atgaatccag aaatatagac
    87361 agccattgtt acagcgagtc cccaaccaaa tgcgatgaca atccagccag aagcctgtgc
    87421 tttacttttg tttaaattca cagccgcaca cacaccatct ccaagcaaaa ctaggatcag
    87481 tgtcccaata aactccccca tgatttgagt catatcactg ttcatttatt tctccccctt
    87541 tagttcccgc agatctgatt ctgcaatcaa tgcttctaaa cgtttagtct gttgcgcctt
    87601 ctcctcttct gtccattcaa aatatccagc aattgcatcg atcacaggtt gcttgatctc
    87661 atcaagctga tctcgttcaa acaacagatg atttgtacga cgaatgagat aatcgcctgg
    87721 ggccaaaacc atttcttctt ctaaaccata acgtaaccga gctgactcag cgagactcaa
    87781 accaggataa ggtgccattt cttttgctaa ttcaaagata cgtcgggcat tagtcccgta
    87841 aaaatcagcg atataagtag catcttcttc ctctaaaccg gctgctactc cttcttttgc
    87901 taattctgtc actgtttctt ctaatttagt tggatcgaag tttccacctg aaatctgata
    87961 ttttttagag tcgatttctt tcgtctctat tccgtattct tcttttaata attggcgtat
    88021 caatcgcaaa gctccttctg ccatcttacg gtaatcggtg attttcccac cagataaagt
    88081 cagcaaacca tctggttctc tttctaaaga actacctctg gaaatcgtag aaggtgcttt
    88141 ttcatcacgg ctgttttcca aatggttcaa cacgtcttct acttcagcac gagaaacttt
    88201 gttttcctta tattcactta ctgtatcgac aactttattg aagctcttgt ctgaaatcga
    88261 tccattatct ccaccattgt aatcagaacc agaattacca atcaacagtg gacgaagtcc
    88321 tgcccagctt gcttcgatat cattcaatgt gatatttgct tctggatagc gatgattgat
    88381 cacatccaat agataatcta catcttcttg tgtgactttc ggatccgtaa aatctccttg
    88441 gtaatccgta tctgtcgtac caaagtaagt cttgttttct cttggaatag caaaaaccat
    88501 ccgcccatct tgctttcctg tatcgaagta tgtgggttgc ggtacaggca gttttttcgc
    88561 atctacaact aaatggatcc ctttagttgg acgcatttta ggagagactg gacgcgtaaa
    88621 attcaagttt cgtactttat ctacccaagg accactcgta ttgatcacta attttgcttt
    88681 gatttcgatc acttcatctg tcagcaggtc acgagctttg acgccaacga tttgatcgcc
    88741 atcatataaa aagccaaccg ctttcatttt acttactaga taagccccat cttcggcagc
    88801 ctttttgata ttatcaatca ctaaacgggc atcattgttg cggaaatcta gatagacacc
    88861 cgcgcctttt agcccttctt ttttcaaaaa cggttctctt tccaatactt cttctggtgt
    88921 cagcgtataa ttctcatatt tggttcctgt cacatttgcc agtttgtcat aaaggtccat
    88981 tgctactttg accgagaaca tattgaaggt tgttgctcct tcgccctcat agattggcaa
    89041 aagcattgga tctggttttg ggatgtgtgg ggcaatactt tgtacgactg cacgttcacc
    89101 aactgtgtca gctactactt ccacatcaaa tgtcttcaga taacgaatac cgccatgaac
    89161 aagtttggtc gagcgagagg aagtcccttc tgcaaaatcc tgcatttcga tcaatcctgt
    89221 tttgattcct gatgctgctg actggactgc cacaccggca ccagtgattc cgccaccgat
    89281 gatcaacaga tccaattctt cttgctgcat tttttgaatg ctatcttgtc ttgtcttgtt
    89341 tgaaaacata tggatttcct ccttattcaa atgcttgggt agcttttact gcttttttcc
    89401 aaccgttgta aagtttttct cggcgctctt cctccatttg aacttcaaat agcttgccag
    89461 cttcataaaa ttcgcggatc tcgtctgtat ctttccaata accgacagct aatcctgcta
    89521 aaaatgctgc ccctagcgcc gttgtttcca agttttctgc tcgttggatc ggtacattca
    89581 agatatctgt ttggaattgc atcagatatt cattgtttgc tgcaccgcca tctactttca
    89641 atacaggaat cttgattcca gtgtcatctt gcatcgtatc gatgatatct ctcacttgat
    89701 aagcaatcga ctgtaaagta gctttaatga tatcttcttt tgtcgtacca cgtgtcaagc
    89761 caaacatagc ccctcgtgct gcctgatccc aataaggagc acctagccca acgaatgcag
    89821 gaacaacata aacctcatct tcgcttgtag agcgtttcgc tgcgtcttct gaatcgctag
    89881 ctttttgcaa catttgaagt ccatctctca gccattgaat cgaagaacca gccacaaaaa
    89941 tacttccttc taaagcatag taaacctttc catttatgcc gtaaccaatt gtcgtcaata
    90001 aattattttt ggataattgc ggtttttcac cggtattcat gacaataaat gaacctgtac
    90061 cataagtatt cttgaccatg cctggttcga atgccatttg tccgaataat gcggcttgct
    90121 ggtctcctgc catccctgaa attggtgctt cgcttccata aaaatgataa ccttgcgtat
    90181 aaccataaac ttctgagtta gaagtgactt ttggtaacat cactcgagga atatttagta
    90241 aatctaaaat ctcctgatcc caatctagct gatggatatt gaacaacatc gtccgactgg
    90301 cattcgagta atcagtaaca tgtgcttgtc catcggtcag tttccatact aaccaagaat
    90361 cgatcgttcc aaacatcaat tcgccttttt cagctcgttc ttgcgcgcct tctacatgat
    90421 caagaatcca gcgtatcttc gttgctgaga aataggcatc gatcactaac cctgtttttt
    90481 cgtggaaaaa ttcttgatag ccttcatttt ttaagttatc tgcaattcca gctgactgtc
    90541 tggattgcca aacaactgca tgatagattg gacgtcctgt atctttttcc catattactg
    90601 ttgtttcacg ctggttcgtt atgccaatcc cagcaatctg atttggtttg atccctgatt
    90661 cgatgaacgc tccggcaata actgactgta cagaattcca gatttcattt gcatcatgtt
    90721 ccacccaact ttcttgcggg aaatattgcg tgaactcttt ttgagaactg ccgatgtgtc
    90781 ttcctttctt gtcaaagata attgctcgtg agctagttgt accttggtca atcgccatga
    90841 tatacgttga ttctgtcatt gtgattccct ccatcatatg caaacgcttt ctttaactac
    90901 tcttatcata ctactgtttt aaaaaaagaa actgtcaaaa ttttattctt tttttctttt
    90961 tttgacagtt ttttattatg aagctatttt ttaatcaatt cttttctttt ttcagcgtct
    91021 ctattcttct tttcaatcga ataatgtcgt aaggtgacgc aaattctgac agataatatt
    91081 cacactgttt tttgtttctc tggcaaaatg tgatcaccaa atcatattct ttaccttctt
    91141 cataacttcc aatctcaata ccgccgattc ccctcagttc tctgatcaga tattgttgaa
    91201 aagcaatacg ataaatcggc agactttcta aatcgattcc aatcactact ggttttgcaa
    91261 tataaaaatc gatcatcaaa agaacattgg catactggat catcaggtaa ctaagctcac
    91321 tatcttcagc tcttttcctc ggcaattgct gcaccgctgt ttcctgtaat ttcgccagta
    91381 actgtgttaa ggaatgcccg agcattttct gctgctgttc caaaagccga tcacgctcat
    91441 agacttcgat ctttccaaca aagaaaaacc attcattgtt gatctgggaa atttggtagc
    91501 ctactgcctt ttcttctttg attttcaaac gacgaggacg ataatgccat aacatcgttt
    91561 cccgaatgta agtatctaaa acagcggttg gtaacttttt gctccgtgtc aaatcatact
    91621 gataaaatat ttcttcgtct actatcgaaa aagaaacaaa aaagctgtaa aacatcattg
    91681 tttcgtatac attcagttct gctgctgttc gactaagatg catcacgatg attggatcga
    91741 ttgcttgata aagccggtcc gactgataga gtaatttctt ttctttcaaa gttgcgtacg
    91801 tacttttttc attcaatagt ctttttttcg taatcccgag ccagcaagca atctgtgctt
    91861 ctgctgatgc cgtaaacgtt gtttctaata cacggtccaa tcctagaatg aacggtcttt
    91921 tttctggtgt attttgcaaa aaaagcggtc gctgatcttc cgggatatat tggaatagtt
    91981 cataataaaa atatcgtatc tgtagctctt ctccgtataa ttgaccgttt ttgatttgta
    92041 atccaaattc ctctaagagc tggttcaatt ctttgatctt tcgaaaaaca gaagactcac
    92101 tgatattaaa cgctgtcgct aatcgaacga tggatacttg ctgatgttct aataaataga
    92161 cgagcatctt aaacttcaag ctttcctgca ataaaaacaa tagaattttt tccaaactta
    92221 catcttcgtc caacacaagc agcgcctgat actcatttcg ctgtacttct actttttttt
    92281 ccatcattcg gccaatcaat tcaatatctt ccaaatattg atcaaacgag gcttttgaca
    92341 gttggacatg ctctctcaaa ccattgatag aggctgttcc cccttgcaga acaaggtttc
    92401 gcaaaatcag gatctgtaac tgctcttttc tttctaataa tgcttcaatc ttcataggca
    92461 gtattcgcca cctttgacca caccatatct ggcacacggt attctggctg gaaaaatagc
    92521 tcatgttctt ctaactgttc aaacgtccat ccttcttcta ctgcaattgt cagttggtca
    92581 agaaggtgga acatctcttt tttgctttgg agctgtgctc caagaatctt tttttcagaa
    92641 tcaaatagaa atttgagttt aactttgctt tgatttattg ctgtaagctt gtagtctacg
    92701 tatcctgttt caattttttg gggataaaaa atgctctctt cttctgtcaa acctacgctt
    92761 cctaagaaat agccaaacca ctgattgccg actggacgat aggttccctg atcctttgtc
    92821 tgtgagccac taattgtctt gctgacattt cgtgctgtac ggacagcgtt atttactaga
    92881 gaaacataca ttttttcatt tgttggacga aaagttactt ggatcgcatc gccaatcgca
    92941 taaacgtctt tttgagacgt ttgcaagtag tcatctaccc agatcgttcc atcatcattc
    93001 aatgttaatt gttcttccca catctgattg tcgggacgag aatgattagc cagcaaaaca
    93061 agatcatagt tctcctttct tttttccgtc tctacaatag cggtttcatt ttcggtcaaa
    93121 gacacaactt gttcttctaa aaaaagtgaa agcccttgat ttttcatttc ctttactaac
    93181 ggttctgtca tttcaggatc tagataacga aaaagaattg actttcggct ttcgtaaaga
    93241 tggatttgtt tttttcttga tgccaaccct tcagctattt cgattcctgc ttgtcctgca
    93301 ccaataattg caattttctt tgcattcatg atcttttgct gaagagccgt tacgttttgt
    93361 atctttttaa ctgggtgaat aagcgttgat tctgcagaaa tatttcgaaa cttttgattt
    93421 gaaccagtcg ctagaatcaa acgatcaaaa tccaattttt ttcctcctgc taaaacgact
    93481 tttttttctt tcaatcctat tactgtcttt tctgtgtaaa catggattcg atagcggtca
    93541 gtcagttctt ctttcgtgat ccaagaaagt tgtttttcac tggtaacctt tccttttaat
    93601 atcaaattga acccgctggg aatccatcct aacttcgatt gcttttcaat caaatatatt
    93661 tcacttgttg gcatcaattg gcgaagataa atagccgcat gaatccctgc aaacgacccg
    93721 ccgacaatta caatgttcat ctgcattcct ctttcttata aggtgttcta ctgctaactt
    93781 ctcaatcaga aaacacagta ttcataactc gctttcaacc ttatgataca tagcgatgca
    93841 gcagaatcaa ccctctccat cataccgtgt tctaggtctg cttctcaata atgtactagt
    93901 ggacctaatt gaagagtatc atttctgaag agatgtttca aaaaatgtac tcttataaaa
    93961 gaaaaaaact cgccttttac gtacctctgt ccaaatagga aacagaaaag aacgaaaaga
    94021 cgagttttag cgtgtgtaat gtaatagtta gaatagacac atcatttatt tttaattctt
    94081 taatgcttca acaactgctt cgcctaattg atgagcagat tgaggatttt gccctgtaag
    94141 aagccgccca tcaatttgaa ccacttctga aaaagctgct ccagactgat agtttgctcc
    94201 tttttctttc aaagcatctt ctgctaagaa tggtacttca ttcgttgtac catttgcttc
    94261 ctcttcttca ttactgaacc cagtcactgt acgtccagct aaaatagatt ttccagactc
    94321 atctgtaact ggcaacaatc ctacaacacc gtgacaaaca gctgagacca gcccttcatt
    94381 tcgatagatt tgtgaagcga ctttcccaag atctattgct tctggaaaat cccacattgt
    94441 tccgtggcca ccagcataat aaaccgctgc ataatcattt gcatccacat catcaggacg
    94501 taaggtattt cccaaggccc gatttctgaa atcttcatct tcataatagg cccaatcgat
    94561 ttcatccata ttcaaaacac tttgcggttc taaaggtaca tatccgcctt taggactgac
    94621 aaaatctgca tcgatcccat tttttactaa tacatcataa aaatgagtca gttcacttaa
    94681 ccacaaacct gtaggacgct cgatcttttc gtacttttct acatttgtta atacgatcaa
    94741 tactttcatt ttcccatcct ctttctataa aaattgcgtt attgataacg tgctttcaag
    94801 aaattatata atgggcttgg caaataaagc tctttatatg ctttttcaaa aggtttcgtt
    94861 acaaattcat cctcacggtt ttccaataat ttctctgccc agtcaggatc gacgatcatt
    94921 tgctgtccaa ttgctgcaag ttctgcatat ttcaatacct gctctacatc ttcgcgattg
    94981 cggatcccac cgacaccaac taaagggatc tttccttgaa tcgtgttatg gaccacttca
    95041 agaatcgatt tatcgttgta tttatcagaa cgagctattc gatcatacat atttaatgaa
    95101 acatgcagat aatctagttt tgactcacgt aatcgttcaa gaagccagat cgtgtcttca
    95161 aaacggatac ctggtgtttc atattcttct ggtgagaaac gataccctac gatgaatggt
    95221 tttttagcat attgttcaac cgctgagaaa accgttgtta ataattcttc aataaaacga
    95281 taacgatttt ccaagctacc gccccattga tcctctcgtc tattcgaatg cggagagaaa
    95341 aattgttgga tcaaatacgt atttgctcca tgcaactcga ttccatcaaa tcctgattca
    95401 atcgctctac gtgtggcttt gccaaatgct tggattgttt caacgatttc ttcttcactc
    95461 attgctcgtg gtgtttccgc atcaggacgt tttgctgcaa ctgcacttgc agatacaggc
    95521 tgttctccag ataaagttgc tcgacttgtc attcgtccac cgtggaaaat ctgaataatc
    95581 gcttttgcgc cttctccttg gattgctttc gctagctcac ttaatcgagg aatcatttca
    95641 tcatgagcga tgctgagttc acctggccag ccttttccga tatcttggac atttgcagca
    95701 ccagtaataa cagcaccaag acctttagaa cgttgtttat aataagtgat ctcatcttcg
    95761 gtgatcactc cattgaaaaa gctgagttgt gtcgtcatag gcgacagcat caatcggttc
    95821 ttcaattgaa ctcctgaagg taaagtaatt gattgatcaa attgtgacat tgtcattcct
    95881 cccataattc gctctgatta acctatcgag aatcatctat cattaaacca ctcgattagt
    95941 tgtacatgca actaatttgc ttaaaaaatt ttattttttt tgtaacttat ctgttgcatc
    96001 attcattgtc tgggctaatt ctttacttgc ttcatttccc aaaactgctt tgtatgactg
    96061 atgaagttct tcccagctac catcgacttc cttagcaaat tggcgtcctt gttctgtaag
    96121 ataaactaat gacaagcgac cttcgctaac tgttttgacg tatcctttat attctaattt
    96181 ttcaacaaaa cgagcaatcg ttgatggggc ggaatagagc atttgtgcaa tatctttttg
    96241 tggtattcca tctttttctt ttaatatcaa taaaataaaa ccataagttg gtgccagacc
    96301 tgtccttcta aacgcttcat cagctaattt attcaacatg cgatctagct ttttcacgct
    96361 aaagaaaaga cattcatcta acgctttttc aattggcttt tccatttcat cccctccatt
    96421 ggcgtacata tcatagtatg atttttattt tttgtcaaaa aacacggaat aatgtccgcc
    96481 tcctctgtct agatttgaaa aaaagaagta gccatcttca aagaatttcg gcttgttttc
    96541 gacaaaactc cttctggaac accgtgaatc agaggttgtg aaaaagtcgt ttagttttga
    96601 gtatgaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt tggcttaata
    96661 ccgaaaaact ggcttttgaa caccgtttat atcagaggtt gtgaaaaagc cgtcctgcat
    96721 caagtaataa gaacagccaa acaaaaatag ttcctcatat tttgtcgttt tttgagctaa
    96781 tgccgatggt cagctgattg tacaccgttt attgagaggt cgtgagcctg ccgttgaact
    96841 ccgagtcaca aggagcaatt tcaaaaaaca gcttctcatg ttttatgact atggtgactt
    96901 gtgatcgagg agttggcagg agaatactgt ttattcgtaa agaaggggct gtgacaagac
    96961 ttttgtcaca gtcccttatt tccttttatt ataggatttc gccatttgat tggatgactt
    97021 gtctgtacca atcaaatgat tttttcttta accgtttctt tgtgccattc ccttcgtcat
    97081 cttgatcaac atagatatat ccataacgtt ttgacatttg tgaagtagaa gcgctgacga
    97141 tatcaatgca gccccacgac gtataaccaa ataaatctac tccatctttg atagcttcct
    97201 tcatctgctc aatatgctgc ttcaaatagt caatgcggta atcgtcttga acggttccat
    97261 cttcttctac tttgtctata gctccgagtc cgttttcagc tatgaacagt ggtttttgat
    97321 acctatcata taattgattc aaagcaattc tcaaaccctt aggatcaatc tgccagcccc
    97381 attcacttga tggaagatac ggatttttaa ttcctccagt tattaagttt ccttggaccc
    97441 cttcccaatt ttctggatga gcactgactg cactagacat gtagtagcta aaagaaacaa
    97501 aatcaacagg gtaggctgct aagatttctt catcacctac ttctattttt aagttgacac
    97561 ctttttcttc aaacattcgt tgcgtatacg ctggataata tcctcttgct tgaacatcac
    97621 taaagaacaa agaagttctt tgctgctcaa ttgttttttg aatatcatcc ggatcacaag
    97681 aatacggaac aagaagctga tagctgatca tacaaccgac ttgtgaacct ttgataattt
    97741 catgacaagc ttttgtagct aaagcacttg ctataaactg atggtgtgca ccttggtatt
    97801 tcgcttgttc caaatgggga tggttttctt caattactcc tacgctaaca aaagggtgat
    97861 gttttacaca gttgatctca ttgaaagtca tccaatattt tactttattt ttatagcgtt
    97921 tgaatactgt ttcagcgaaa cgaacgtaaa actgaataag ctttcgatta ggccatccac
    97981 catattctgt aaccaaatat aacggcattt cataatggga aagagaaacg actggctcaa
    98041 tcccatattt tagacattcg tcaaacactt gatcataaaa aaataatccc gcttcattgg
    98101 gtgtttcttc atcaccatga ggaaaaattc ttgtccatgc gatagacatc cgatagcatt
    98161 taaaacccat ttcagcaaat aaacggatgt cttctttaaa gtgatgatag aaatcatttc
    98221 cgtgtctttt aggataataa tacttgctgt tgggatcctg cgccgctttt acttgctgat
    98281 gcgtcatcat atgccattga tctgtccatt tttctttagg taaatcgctg tcgaatgtat
    98341 acacatcaga cacagataat cctttttcat ctacatccca tgcaccttca cattgattgg
    98401 ccgctgtcgc tccgccccat aaaaatcctt ctggaaattt tttcatatcg atccccctaa
    98461 acttgctagt tttcttgttt gattattttt cttatgacta gtaatgatat ttttgaatct
    98521 actactattt gtaacaataa ccattgtggt cggatcatat ccctctttga ttaattcttg
    98581 caaatctact tccatcaata aatcgccttt acgtactttt tttccatcag atactgcact
    98641 ttgaaagtat ttgccattta aattcactgt atcaataccg atatggatca gtatctctgc
    98701 tccttcttca ctgactaccc caattgcatg tttcgttgga aaaactgttg aaacttcccc
    98761 gtttacagaa ctgtagattt ttccgtccgt tggaatgatc gcaaaccctt ctcctaaaga
    98821 tccactagca aatgttggat cgtttacttc agataaatca attatttcac ctgctgcagg
    98881 agtacttaac actatatcct ttgaggattc ttcttcgatt tcatccttgt agccgaaaag
    98941 aaaagttagc atacaggaac tgatcatcgc taagaaataa ctagcaacta gccaaacaaa
    99001 tccttcacca atataaatcg ggaaagacaa aatacttctt gtagcaactg ccaaagcacc
    99061 ggctcctgcg gcaccagcta ctccaccaaa tatagctcca catatacaag caatgtaaaa
    99121 tggtcgttta tatttaagag tcacaccata aacagcaggt tcagtgattc caaataatgc
    99181 tgtgataaat gcagataaag ataaactttt tactttctta tttttcgttt tcaaaaatac
    99241 cccaagtact gctcctgctt gcgcagctac ggcagtcata catgctggac ctagcgtatc
    99301 acgaccgtag aaagaaagat tgttggtcat tactggtaca agtccccaat gtaacccaaa
    99361 aatcactaac acttgccaaa atccgccgat aacagcacca gataaaacag ggctaaagtt
    99421 ataaacagct aaatatccag ctgcaatcag ctgacttgca taatctgcaa ttggacctac
    99481 aactaataaa ataattggga ccatcacgat gatacaaatg aatggtgtca ataaatttcg
    99541 aatactttcg tgcaagcttt tgcgaatctt aggctcaata taagaaagaa cccatacagc
    99601 taaaattgct ggaataaccg tacttgtata ccttgctaga atcacgggca tccctagaaa
    99661 tcgcaaggtt atgctatcac tatatgcact gacaatcgta ggataaacga gagctgctgc
    99721 aataaccata gcgatgaaac gatctgtatt gaactttttt gcagcagtat atgccaaaaa
    99781 tataggcaag aaatagaaaa atgcatcagc tgctgcattc aaaatgatat aagttcctga
    99841 ttcagtagtt aataaattca aactcgtaca taaggcgagt actcctttga tcaaaccact
    99901 tcctgccaag acgcctaaag tcggggcaaa aacagcggcg atcatgtcta taaaagagtt
    99961 taaaatgcct tttttctcag ttcctctctt tccactagat gcatcatctt ctagtttcat
   100021 ttgtttggat aatacgtcat acacttcatt tactgcattt cctactacga cttgaaacat
   100081 tcctccagct tcgactacag tgatcacacc ttctagttgc tctaccttct ccttatctgc
   100141 cttcttatta tcttttaggg taaagcgtaa ccttgttgca caatggtaaa cattgctgac
   100201 attttcttcg cctccgacaa atcggacaat atctttcgct aattgtgaat agtccatttt
   100261 tacttccccc ttgttaatta atgccgtagc aatccttctt acaagataag tatagttctt
   100321 agaaaacggt ttctccattc aattagtacc ccttctaata gcgaacgaaa ctgtacaata
   100381 gtgtgtatgg tttacttagc cgagcaaatc actcactgct tgaaagaaaa caagtatatc
   100441 gtttctctta tagtcaaagg agacaaaaaa aacacgcttg atcttccttt gctgatgtat
   100501 aagtggtatc tcaagctgat actctgtgat ttttgtttct acttggcttt tgataagaca
   100561 gcacaacaaa gtctcggcat ttaacggaag cataactagg tcagaactag gagagattag
   100621 ttgctgaatg gaatctatct ttttatggat ttttatttga ttttcttctt tgtagtaatg
   100681 atcaagcagt tttgttttct ttttttcttc aactatggtc agcttttcac gcaaaatctg
   100741 ataaatctcc caagattcaa actcatctag aacactaggt agataaatca aatcatccca
   100801 ctcaaaaata agctcttgct cagtagtcaa aattgcatca tattccgtta ttttgtttga
   100861 ttgatttttg aaaagataca ctggttctat ccggcattct ttgatccaca tgttcatact
   100921 ttgttgaatc tgttttttta gtgtattcaa aatactaatt ggctggttac taacaatcag
   100981 tatctcccct tgttttcgaa aaggattcaa cgcttcggca agatacaaaa caaaataagc
   101041 gctttcagct aaattgggac gtaattgaaa atgtattggg aagaaacgcc gaattaaata
   101101 aatttctaaa ggataacggg agatgatctt ttgtacaaaa tgattcatgg tattatgtcc
   101161 ggcatccatc ctcgttttca tttgtttgat atgggttagc aaaaattctg tttcatggaa
   101221 caataacgaa acaggaagat ctaaaaaacg aataatcgtt tgctcaaatg ctcttagatt
   101281 cttctctatt tctttgtttt tttcatcatt aatcatcaaa taatttaact ctaatagtcg
   101341 attttcaatt gcttgttttt cttgattgga aaaagaatag ggtagttctg atgataactt
   101401 ttttgtgagg gtctctacca tcggaataaa taatgtatac ctgtttgttt tttctaaaag
   101461 ttcttctctt cgaagaatgg tcaaaacgag ataccgagaa aatcgtatga agtcctctcc
   101521 tgaaacaata taattatatg atataagaac ctcttttaat gtcttttgga cagtcggcat
   101581 gatattggaa aaaattgtac tgatttgttg aggaaacctt gcgtgttgga tcaccgtttc
   101641 tgttccaaca agagataaga aaattctttt tgaattttct tcagcaatga tttttagtcc
   101701 ttttgtcgac gaaacttcca gttctaattt aggattgcgc tcgatccaac gcaaaatcgt
   101761 ttttatttgt aatgatacgg ctgtttttga aagaaagaaa atgtctgcta tcttttgcat
   101821 actgacatac cctttttgaa acaataagta cgtcacaata gttgaagctc ggaaatccat
   101881 gctggaatag attttatgtt tcgtcacctc ttgtatgatt tgctgtttag tttcagattc
   101941 aattgattct aaaaaataac ctgaacgttt atttgactgg ataatgattt tcttctcgta
   102001 gatagcaagc atatttttga tttcagtttg gatcgttttc ttgttggtac ctaaagcttc
   102061 agctaattct tcgcttgtta tccaatgatt cttatttctt aatactacaa gaatttggag
   102121 ttgtcgttta tttaagtcca tttgcttaca cctcctcttt gttataaaca tacaggaaaa
   102181 acctctcaaa tgacaatagt cacttgcaga ggtttaaaaa tcatttgaag aaagatctat
   102241 attcaaggtt tttaccatta gactggataa tttgtttata atattcaaaa ctatcttttt
   102301 tcaatctcct aaagcttccg ctcccatcat tttgtctatc cacataaata aagccatatc
   102361 gcttcctcat ttcccctgtt cctgccgata cgatatcgat tggtccccac cataagtaac
   102421 caatgatttg gcaaccatct tttattgcct cagcaatttc ctgaagatgt atttttagat
   102481 actcacaacg ttttggatcg tggattcgat tcaattcatc tggtgcttca tctagtccaa
   102541 tgccattttc aactatgaat aatggtaatt cataacggtc tgtcaattca ttcatgacat
   102601 aacgaaaccc tagaggatca attggccaac tccaaggttc gggagatttt tccttcaaaa
   102661 agggattatc gaaaccattt gctccgccag tatctacgcg catttctgct tcttttttat
   102721 agacagcgct acgataataa ctaaatgcaa tataatctgc cgtgttagct tgcaagcact
   102781 gttcgtctcc atctaacatt actggtgcac agtcttcttc cttccatgtc ctgtaaatat
   102841 aagctggata atgccctcgg cacatgacat cggagaaaaa ccatgaattg cgtttaaatt
   102901 gcagtgaacc aaatacattc tctggatcac agtcatatgc ataagtcgct aatgcagaaa
   102961 agctacacat aatacccatc ttagcatttg gatcgatttt ctttaataat tgagtagcac
   103021 gggcgttcgc tagaaacata tgatgacagg cttgataaat cacttttttt gttagtgtag
   103081 caatgggttc aagtttatct ctagcaggga atgtaaccaa tccagcagct gcataaggca
   103141 tacgaaaagc attattgatc tcattaaagg tcatccaata tttcactttc ccttggtagc
   103201 gttcaaagac ggtctgcgca taaaattcaa aaaagtcgat taattttcga ttttgccacc
   103261 ccccatactc tcctaccaat gctaaggggg tttcataatg actaagagta attactggct
   103321 cgatatcata tcgatttaat gtattgatta gtctgtcata aaatacgaga ccagcctcat
   103381 ttggcttctg ttcgtctcct cttggaaata ttcgtgccca tgagatgctt gttcgaaaag
   103441 cttttaaacc taactccttc agtaaacgaa tatcctcttc aaatcgatga taaaaatcaa
   103501 tcgcttcatg agaaagataa tggagtgatt cgtctaaagc aatctcccaa atcttttttt
   103561 cttcattcca ctgaatacta ggatgctggt tcatgatccc gataagcgta tctgtcacat
   103621 taggtaattt gccgtcttcc aaccatgcac cttcacattg attagcagct actgctccgc
   103681 cccataaaaa attttctgga aatatttcct gatccataac tatctctcct cgctatcaac
   103741 aatttcttac ttgaagtata gctcgattca tcaaaacaag atattctaac tatttcggca
   103801 gaagagaaga aaaaaattga atgctactct tcatttttaa tatttatata taacaaatac
   103861 ataagacgat ccccgaaaga aaacactcgt taaccatcta agcaaacgat ttattttact
   103921 tccaacacaa atgcttcata aggtcgtaaa tcaactttgc cgtctggtaa ctgtttcaga
   103981 ggataatttg acacaataac ccttaaagct tcacgtggaa tagtgaacgt ctgcttttca
   104041 ctggacatat tacaaataac gagccattgc tggtcttcat atatgcgaga ataggcaaag
   104101 acatgctcag gcgtcttttc cactaattca tagtctcccc agacgatgat gtcatgtttt
   104161 ctacgcaaat cgatcaattt cttgtacata taaaaaacag aatcttgatc tgctaacgct
   104221 tcttctgcat tgatttcttt ataatttgga ttgactcgaa gccatggaat tccagtagta
   104281 aacccagcat gttcacgggc gttccattgc ataggcgtcc tagcattgtc tcttcctttc
   104341 gccttgattg attccaagat ttcctctttt gtaaatccag aagaaatcct ttcgttatac
   104401 atattgattg tctcaatatc ttttgcttcc gcgatatcat cgattgggca attcgtcatg
   104461 cctaactctt ctccttgata gatataaggg gtgcctttca tcatatggag caagatagca
   104521 aacatcttgg cactttcttt tcgatacaca tcgtcatttc cccaacgaga aacaattcgc
   104581 ggaagatcgt gattattcca aaataaacta ttccatcctt catcacctaa agatgtttgc
   104641 catttggata atactttttt cagttcagag atactcaagg gtttcaaatc ccatttgtct
   104701 ttgccttctt gctgatctaa tcctatgtgt tcgaattgga agaccatgga taattcattt
   104761 cttttaggat tggaataaag tttagcgatt tcggtagttg ctccccatgt ttcgccaaca
   104821 gtcatcagat ttttgtcacc aaaagttgct tgattcattt cctgaagata ctcatgcagt
   104881 ttaggtccat tacttgtgat ttctttatcc ggttctttgc caatcatatc gatcacgtcc
   104941 atacgaaagc ccccaatacc tttatcgatc cagaaattca tcatttgata aatctcttgg
   105001 cgaacctgtt tatttttcca attcaaatca ggttgacgct tgctatacaa gtgcagaaaa
   105061 tattgccccg ttttttcatc caactgccaa gcagaaccac tgaatattga gcgcaatcta
   105121 ttaggctctt ttccattgac cggatcacgc caaatataat agtcccgata aggattttct
   105181 ttatttttac gggcctcaat gaaccacgga tgttcatcag aagtatgatt caccaccaga
   105241 tccatgatga tacggatatt tcttttcttt gcttcttcaa tcagttcttc catttcttcc
   105301 atcgtaccga attctgccat gattgcttga taattactga tatcataccc attgtcatca
   105361 ttcggagact cgtatactgg agaaagccaa attgcatcaa tacctaaata cgccagataa
   105421 tccaacctgg aaataatccc ccgcaaatct ccaataccat cttgatttga atcttgaaaa
   105481 cttcttggat agatttgata aacaactgaa tggtgccacc atttttgttc catgattttc
   105541 ctcctataaa tggatgtttc tattttttgc ttaatcattt attttagtct ctctcactaa
   105601 aaattgtaac gctttcaaat agctattgca ccttgttatc ggtaacagaa taaaacaaaa
   105661 aaacagctga ggaaattccc tcaactgttt tttgaaagga ttgatttatg cagggaagaa
   105721 tgctgatttc acaacttctt tataaacggt gttcactcag ctgtcccttg gtattagctc
   105781 aaaaaacggc aaaatataag aaactatttt ttcgtttttt tctctaatac tcaggccaga
   105841 acgctgattt cacaacctct ttatttcaca ttcaatatcc acatgaatcc cacaaataca
   105901 aagaacagac catacatgat tggagatact tcttttcctc ttttagctgc taacatggta
   105961 attggataga agataaaacc taatgcaatc ccatctgaaa tactataagt caaaggcatg
   106021 ccgatcaaga tcaagaatga agggatcgca atctctaagt ttccccattc gatttgtcgc
   106081 aaagattgtg ccatcaatac tcctaccata atcaatgctg gtgcagttac ttgtgaagta
   106141 acaactgata gtaatggaga aaagaacaag cctaacaaga agaaaatccc tgtagtaata
   106201 gctgtgatac ctgaacgtcc tccaacggcg ataccagctg atgattctac aaatgcacca
   106261 acaggagaag taccaaataa ggaacccgca agcatagctg ttgaatcaga agctaaagct
   106321 ttccctacac gaggcatctt gttgtctttc atgaaacctg cttggtttgc taatccaact
   106381 aaagttcctg ctgtatcaaa gaaagtcaca agcaagaatg tcagcactac gacccacatt
   106441 tgaagagaat tgatgtcccc tacatgtttt aatgcaacta aaaatgttgg tttcaaactt
   106501 ggtgctgcgg caacaatttc agaaggcatt ggaatcaaac ctgtgaccag acctaaaatc
   106561 gttgtagctg ccatcccgat gaagatgcca cctggtacac gccgaacaag caagatagca
   106621 gttacgacta atccaaaaat cgtcaaccaa gtagaaccaa cgttgagtga tcctaatcct
   106681 actaatgtag attcattcga aacgatgatc ccaccttcgc tcagaccaag gaaagcgata
   106741 aatagaccga taccgccaga aatcgcatat ttcaaatctg ctgggatcgc atcaatgatc
   106801 atttcccgca gcttgaagat tgtgatcaaa ataaaaatca aagaagcaac gaatacgccg
   106861 gctaatgctg tttcccatgg aatccccatt cctaaacaaa cagaataagc aaaaaaagca
   106921 ttgatcccaa gagcaggtgc cgttccaatt ggataacggg ctaatacccc cattaaaaca
   106981 cagccgatcg cactggctaa tgcagtcgca gtaaacactg ctccttcatc cattccagaa
   107041 gcacctaata cagttggatt tacaaataag atataagcca ttgagataaa tgttgtaaat
   107101 cctgccagta cctcacgttt taccgtggtg ttcaattttt ctatttcgaa gtaggaaagt
   107161 attttttcct tcatcttcca tccccctaaa tccgaacatt ataaataaag tccgttaaaa
   107221 tttcgattta ttaataaaac aacgtgtttt atcatatact aaaacaaaac ataagtaaac
   107281 aaaaaattcg gattttaagc aaaatccgaa cgttccatct gattaaatcc ctttatctca
   107341 aagttcatga acattcactt tggattacaa gaatttcttt attgtgttaa taaagtttct
   107401 tcattctagt ctcaaaaatc aatagtgtga tttgatttta ccatttcgtt tctgttcttc
   107461 tttgatgaat tcttttgtat cgacaggatt cagattattt agtccgccaa aacctgtatc
   107521 gaccattttt ccccagcctt ttgtcttctt ttttcctgat ttgagattct ttgctcgaag
   107581 cttctcacta tgttttgctc gccgatactt caaataacct tctaatcttc ccattagatc
   107641 cactgttttt cctccttttt attcaatcag acgactcagc ttttcctata acaaaataat
   107701 tgccttcagg gtcagaaaaa ttgaaagtca agatgccatt gttatctgtg atttctcctg
   107761 gttcttccat gttctcgtag atagtttcaa attcatccgt aaaaaatact aaagaaggcg
   107821 gtggtcctaa tacctctggt gaaaacttct gcacaaatac ttttgggaat acgcctaatt
   107881 ctaattcttt tgagatgctg agtacaatac tcttaaattc ttctggcaat tcgattgttt
   107941 cagaaatttc tgcaccaatt ttttctacaa agaatcggca aatcatctct acgtcattga
   108001 cataaagcat cacacgtgtt ttttgtatca tcatttgacc cttctttcta tttgattttc
   108061 tttcctgtct ataaactgat tccattatat cacgaaagcg caaacacctt gtgtttgata
   108121 ctattcaaga aaaataaagc aatagtttct aggattgctt tcctccacaa acttttttta
   108181 caaaaaaaaa acggcaatga atgccgctct tcttatttcg attcttttat aattctgctt
   108241 ctgattcatc tttggttagt gtgtgtctaa cactagttac gccaaatgtt tgatcgattt
   108301 tttccttcaa cgcttcgatt gcctgtgcgc cacgtgccgc ttgttcagca ttgatggatt
   108361 caatgaccag caccgctgct tgtgtttctt ccgtcagcat cgttctttgg gcttcacgcc
   108421 agttgagaca gcgacagatc gctccttgtt catcatagta gatgatttct tccggaagtg
   108481 ccggagcatc ggaatctgca cctaaaggca ggaatgattc gccaccttgg gcttttccta
   108541 aatgcagatt tcctgcgatc ttttcgatat cttctccgcc gcaaggtacg ccaaaagaca
   108601 aggaaatact attatagata tctacaagcg gattgattgg gaaaaattcc cgttcttgat
   108661 ttgcacgttt cagtaaagct tcaatagaag aacgtgcacc ttttttagtc ttgaatgtgg
   108721 taaatgcctg acgccactga gcaatgactt cgttttggct gaatgtttct tctgtaaggt
   108781 aatttcttgc ttcttttgct gcctcattca ataattgatg atacgtttct tcactttctt
   108841 ttgttacgtg gttatcgata ccatttacgg ataagatttc gatggttgct tcaggaaata
   108901 cttcccagaa attggtatcc actattactt ttttcatctg ttcacacctc ttgattagaa
   108961 taattgcttg atgaatagat agtctgtttg gggatcatct cccatataaa aaacatgttc
   109021 gctgtatttg ataaatcctt ttttacgata aaaagcgagc gcaacatcgt tgtgttccca
   109081 aacaccgagc caaatggctg ttttttgctt ttcttttgct ttttcaatag ctgtatctag
   109141 taaaaatgta ccgatacctt gatgtttaaa tttttttcgt acatagattc gctcgatttc
   109201 taaaaaatga tcagccattt cctcagattg actcgttcct gtatttagtt tcaggtaacc
   109261 cgcaggctct tgatcgatac tcactaggaa aaaatcggtt tctttatctt ttagctcttc
   109321 tgtaagtttt tctagtgcat aagcttgtgt caagtaatca gctaaatgct ccggtgaatt
   109381 atcttttcca aatgtatctg taaatgtttc gatactaatt tgttgtagta agtctacatc
   109441 tgaaggcgtc atttttcgaa tttcgtattt attcacggct tcttcctttc aatagatcct
   109501 tttattgcct tttttgacaa aattccaatc ttcgctaaca ttcttgcata ctttatttaa
   109561 aagatattcc aattgttttg cttcttcgtc agaaagacca tttaatgcga ctgcattgga
   109621 gtagttgttt tctcgaatga tgaaaggata gatttctgct ccttttttag tcggatagag
   109681 tttcttgatt tttttatttt ctttatcttc caaacgttcg atcatcccat tggattctaa
   109741 tttcttgatt gctcgggcag tcgttgtacg atctactttg atcatttctg ctagtttttc
   109801 ttggatgatt ccaggatttt cgcaaatacg tactaaataa agatactgtc ctcttgttaa
   109861 atcgacttct ttgaattcga tattgctaat agaatctagc gctcgggcaa tcattccgat
   109921 gtctcgaagg atttcagcca tttcatccca cctttatttt gtttgtaaga ctagttcacc
   109981 tctttttgtt gcaaatgcaa ctattttcaa taaaaaaatc aagttctttt ttaataacta
   110041 gtaaagtata ttcttttctt cttttacgaa aaagctcaat cacaatagat ctggtttttg
   110101 ttttctaaaa taagtaactg tttcttcgtt gttcgctttt ctgatagctt tggcaactct
   110161 tctatactaa aaaatcccat gttggaagtt tcattattct caataaactt ggcctcttca
   110221 ccgtggatcg cacaagcaaa aacaagttta taatactgaa aaagctgtgg aatatctttt
   110281 tgtttattcg tatcaaaaac tgctcgcaac tgagtagttt ctactgttaa tcctgtttct
   110341 tcatagactt ctttacgcac attttcttca ggagacaatc ctatttcagc aaatccacca
   110401 ggaagtgacc attctttcgt ccgtttatct tcgattagta ggaccttgcc atcttttttg
   110461 atataggcac gaacatctac ttttggtgtt ggatgtcctt ctccaatcgt tgtgagcgct
   110521 tttatttctt cgaaagtttc ttttcctatt tcactgatca gttccaatga aatcgtccgg
   110581 atctcctcaa aacgctcttt atcaaataca tcttttccat aatatagacc agcttgagaa
   110641 agtgcgagta gtcttttgta ttgagccaac ttcttgttca ttctcttccc ttctttttta
   110701 gcaaatgtat gactatgtaa tcaagtatag aagactggtt taattacggc aaataaatat
   110761 aatgaaatct gcaataaata aaagaatgtt aaaaaactcg agaacaaaag acattcgact
   110821 tctctggggc tgtgaataaa tggcgttcaa aagcttgcat ctgcggtaat aagccccacc
   110881 aaacgaaaaa tatgacgagc tattcttgtc tggctgttct tattaattga ggcaggacag
   110941 ctttttcaca acctccccac taaacggtgt tctcctacca actcctcggt cacaagtcac
   111001 aatattcatc aaacatgaga agctgttttt ttgaaattgc tccttgtgac tcggagctga
   111061 acgacaggct cacgacctct cggtaaacag cgttcaaaag ccaatttttc gatattaagc
   111121 catttctttg ttacttattg tcattgattt ctttttctaa tttatccaat agtggagtgt
   111181 aatccacttg agtatagtct gttacatcaa attcatatag tgttcctaac tggaatttgt
   111241 catattttcg gtcggcgatg atctttttga atgcttcttt cgtaatatga ttggtccctt
   111301 tcgttcgatc ttccaatacg tcaccatagt gataatgatc catgatatag ctcaaatgac
   111361 gatctgattc acgatcacgt ttgtaccgac gttgccataa cacttcaaag tctgctgtta
   111421 ggcgaatcgt gatcacctga tatccgtatc tatctgctaa ttcttggagt cgtgcttttt
   111481 gcttatcact aaaaggatac tcggacacaa tcactttctt tcctgcttcc atatacaaat
   111541 caagtgcttt gtaatagaaa ggataaactt tcgtcctttc ttgttccgcc cgttcttcca
   111601 aattgttaaa cccgatggat tctgcatagt attccttgat ttcatcgagc gtgatggcat
   111661 acatatctgg aaatcgttcc cgtagtttat tcataagata tgtttttcct gtaccaggac
   111721 taccagccag aagaatgaaa tactttttca tctcatttat ttcctaagtt aattggactt
   111781 tccaagttca taaacagtcc aatcttatgc ttgacaattt cttttactgc ttcatttgct
   111841 ggaatcacat tatggcgaag agacttgttg atttctgttt cactaaaggt ttctttagct
   111901 actttcgtcc agttgactaa aagctccgtt ccaacattga atttgcggat cccgttattg
   111961 atcaattcag gataatcttc ttctttcaca cctgttcctc catggataac tagggggaca
   112021 tcaactactg catcgatttc tttcagcaag ggaatgttta cttctgtttt tgatttgaat
   112081 tgtccatgat tcgtaccgat agcaatagct aatgcatcca cgcctgtagc ttctacaaat
   112141 ttcactgcgt cttccggtct tgtatatacc ttgtcatttt cagcgacatg gattccttct
   112201 tctgtaccgc cgattgttcc aagttctcct tctacggaaa caccgtgcgc atgggcatat
   112261 tctactactg cttttgtctt caggatattt tctttgaaag gcagatggga cccatcatac
   112321 atgacagaag tatatccgct gtcgattgct tctttgatat catcaaagtc tcgggcgtgg
   112381 tctaagtgca agactgcatc aaccatttct tcttctgcaa tagctgtcat tacattgact
   112441 aacacatgca tgccgatata tttagcggta tcgacacttg tttgaataat gatcggcgaa
   112501 cccatttctt ttgctgcgcc tagcatagca ggaagcattt ctaggttatg cgtattaaaa
   112561 gctccaactg taaaattcaa ctcttctgct gtttttgtta cttctttcaa tgttgtatac
   112621 atcttttatt gccaccttat ctttttattt gtttcctttg atcgttactt gttttgcaat
   112681 ttgtcgcatc tcatccattt tgcccatgta gtaatcgatc ccttgatcat caccagcacg
   112741 agcagcatct gcacgcttct ggttatagag gctcatcagt tttttatacc catctccgat
   112801 cgtctgttta ttttccaaac tcttttctaa atattggatg gcttgatcgt tcacatacaa
   112861 ttcagaaaat ttaagtccaa cttgttcata aagtttcgct aatttatgct tatcttgggt
   112921 agtggaaatc tcttgtttca attgtgtaat ctctgattga atcttttcgg tcgcttctgg
   112981 cgatagggct ttttcttctt ttgccagaac ttttttcggt tctttttctt ttttcttaaa
   113041 aaatccaaac atcattttcc ctactttcaa ttaaaatgct ttcaaaactg ggcttaagat
   113101 ccaggcatat aagagtgctg cggctactgt atctacatcg gttgctgtag cattgttgaa
   113161 tcccatcgaa ttaaagatcg ttactagcaa agcgggcaat aatgtaataa agaaaccatg
   113221 agcaataccg ccaatgatcg ctcctcggcg tccgccaact gcgttgccaa atatccctgc
   113281 tgtccctccg gcaaagaaat tggttagcat accaggtaaa atcatcgcta agccgaacat
   113341 gggcaaagta aacatggcaa taatcgtacc aatcgttgtc gtaatgaaac ctaaaatgac
   113401 agcatttggg ctataaggaa agaaaactgg acaatctaag gcagggatcg catcaggaac
   113461 taatttcata gctatccctc gaaatgccgg cacgatttca cctaacagta gacgtacacc
   113521 agctagcaat acatacacac ccactacgaa ttggatggct tgtaaaaagg caaacatgat
   113581 atagttttga tctcctgata attcagaagc gaatggttcg cctgcaaata aaacagtgat
   113641 gatatatagc gggaccatca cgaccatgac agacaaataa gtatcttgca gaaattcgaa
   113701 atgtgtcggc aacttgatat cttcgatcga ctttttattt tcgcctttct caccaaaaag
   113761 cttagcaaca ccggcttcaa ataagtaccc gatcgtacaa aaatgaccta aagcaatatc
   113821 atttgatcca gtgattttac gaatgatcgg ttgcgctact gccggcatag caatggcgaa
   113881 acaagctccg ataaaaccac cgaccaagat caatacgatc cctcgcagac cggcaaaata
   113941 gccaaagact gtcgtcatcg ttgccatcca taaaattgct tgaccagtta aaaaaatgta
   114001 cttccatttt gtgaaacgag ccaaaataat attgaataca aaaatggcta agaacgtcag
   114061 tgcaatatct ctacctaaac ccaaatcatt cattgcttga ccattgatag attcaataga
   114121 agggatgatc ccttgcatat gaaatccttc agtaaagatt ttcccgaaat aagttaaact
   114181 tccaacgatg atgctcgaac cggcactcaa cacttgaaat cctaggagtg tctttaacgt
   114241 gccagagatg acttgtcctg ctgatttctt ctgcagtagt agacccaaca tagcaatcaa
   114301 tgcaatggtg atcgatgcct gagtcaaaat attttcgatg ataaaattga taacgcccat
   114361 g
//
LOCUS       DAZKCH010000002        87873 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000002 DAZKCH010000000
VERSION     DAZKCH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 87873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.002"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            207..1208
                     /locus_tag="ACG84X_000100"
     CDS             207..1208
                     /locus_tag="ACG84X_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFP9126011.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQSMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            1227..2246
                     /locus_tag="ACG84X_000101"
     CDS             1227..2246
                     /locus_tag="ACG84X_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFP9126012.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2348..3064)
                     /locus_tag="ACG84X_000102"
     CDS             complement(2348..3064)
                     /locus_tag="ACG84X_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9126013.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3033..3818)
                     /locus_tag="ACG84X_000103"
     CDS             complement(3033..3818)
                     /locus_tag="ACG84X_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9126014.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3809..4558)
                     /locus_tag="ACG84X_000104"
     CDS             complement(3809..4558)
                     /locus_tag="ACG84X_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFP9126015.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4856..5380
                     /locus_tag="ACG84X_000105"
     CDS             4856..5380
                     /locus_tag="ACG84X_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFP9126016.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5396..6895
                     /locus_tag="ACG84X_000106"
     CDS             5396..6895
                     /locus_tag="ACG84X_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFP9126017.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6983..7585)
                     /locus_tag="ACG84X_000107"
     CDS             complement(6983..7585)
                     /locus_tag="ACG84X_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFP9126018.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7689..8645
                     /locus_tag="ACG84X_000108"
     CDS             7689..8645
                     /locus_tag="ACG84X_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFP9126019.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8950..9906)
                     /locus_tag="ACG84X_000109"
     CDS             complement(8950..9906)
                     /locus_tag="ACG84X_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9126020.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10080..10640
                     /locus_tag="ACG84X_000110"
     CDS             10080..10640
                     /locus_tag="ACG84X_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126021.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10633..11457
                     /locus_tag="ACG84X_000111"
     CDS             10633..11457
                     /locus_tag="ACG84X_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFP9126022.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11467..12084
                     /locus_tag="ACG84X_000112"
     CDS             11467..12084
                     /locus_tag="ACG84X_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFP9126023.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12102..12785
                     /locus_tag="ACG84X_000113"
     CDS             12102..12785
                     /locus_tag="ACG84X_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFP9126024.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13468..14751
                     /locus_tag="ACG84X_000114"
     CDS             13468..14751
                     /locus_tag="ACG84X_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9126025.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14767..15654
                     /locus_tag="ACG84X_000115"
     CDS             14767..15654
                     /locus_tag="ACG84X_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9126026.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15671..16507
                     /locus_tag="ACG84X_000116"
     CDS             15671..16507
                     /locus_tag="ACG84X_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9126027.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16510..17133
                     /locus_tag="ACG84X_000117"
     CDS             16510..17133
                     /locus_tag="ACG84X_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126028.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17130..18422
                     /locus_tag="ACG84X_000118"
     CDS             17130..18422
                     /locus_tag="ACG84X_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9126029.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18781..18878
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18994..19575
                     /locus_tag="ACG84X_000119"
     CDS             18994..19575
                     /locus_tag="ACG84X_000119"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFP9126030.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19578..20885
                     /locus_tag="ACG84X_000120"
     CDS             19578..20885
                     /locus_tag="ACG84X_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFP9126031.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21301..21789
                     /gene="purE"
                     /locus_tag="ACG84X_000121"
     CDS             21301..21789
                     /gene="purE"
                     /locus_tag="ACG84X_000121"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFP9126032.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21782..22906
                     /gene="purK"
                     /locus_tag="ACG84X_000122"
     CDS             21782..22906
                     /gene="purK"
                     /locus_tag="ACG84X_000122"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFP9126033.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22919..24214
                     /gene="purB"
                     /locus_tag="ACG84X_000123"
     CDS             22919..24214
                     /gene="purB"
                     /locus_tag="ACG84X_000123"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFP9126034.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="ACG84X_000124"
     CDS             complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="ACG84X_000124"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFP9126035.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(26293..26670)
                     /locus_tag="ACG84X_000125"
     CDS             complement(26293..26670)
                     /locus_tag="ACG84X_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126036.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            26926..27654
                     /gene="purC"
                     /locus_tag="ACG84X_000126"
     CDS             26926..27654
                     /gene="purC"
                     /locus_tag="ACG84X_000126"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFP9126037.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            27654..27908
                     /gene="purS"
                     /locus_tag="ACG84X_000127"
     CDS             27654..27908
                     /gene="purS"
                     /locus_tag="ACG84X_000127"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFP9126038.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            27910..28581
                     /gene="purQ"
                     /locus_tag="ACG84X_000128"
     CDS             27910..28581
                     /gene="purQ"
                     /locus_tag="ACG84X_000128"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFP9126039.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            28582..30804
                     /gene="purL"
                     /locus_tag="ACG84X_000129"
     CDS             28582..30804
                     /gene="purL"
                     /locus_tag="ACG84X_000129"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFP9126040.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            30789..32228
                     /gene="purF"
                     /locus_tag="ACG84X_000130"
     CDS             30789..32228
                     /gene="purF"
                     /locus_tag="ACG84X_000130"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFP9126041.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            32251..33303
                     /gene="purM"
                     /locus_tag="ACG84X_000131"
     CDS             32251..33303
                     /gene="purM"
                     /locus_tag="ACG84X_000131"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFP9126042.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            33300..33878
                     /gene="purN"
                     /locus_tag="ACG84X_000132"
     CDS             33300..33878
                     /gene="purN"
                     /locus_tag="ACG84X_000132"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFP9126043.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            33875..35410
                     /gene="purH"
                     /locus_tag="ACG84X_000133"
     CDS             33875..35410
                     /gene="purH"
                     /locus_tag="ACG84X_000133"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFP9126044.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            35426..36700
                     /gene="purD"
                     /locus_tag="ACG84X_000134"
     CDS             35426..36700
                     /gene="purD"
                     /locus_tag="ACG84X_000134"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFP9126045.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            36822..37736
                     /locus_tag="ACG84X_000135"
     CDS             36822..37736
                     /locus_tag="ACG84X_000135"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFP9126046.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(37869..39434)
                     /locus_tag="ACG84X_000136"
     CDS             complement(37869..39434)
                     /locus_tag="ACG84X_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126047.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(39427..40878)
                     /locus_tag="ACG84X_000137"
     CDS             complement(39427..40878)
                     /locus_tag="ACG84X_000137"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9126048.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(40892..41908)
                     /locus_tag="ACG84X_000138"
     CDS             complement(40892..41908)
                     /locus_tag="ACG84X_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9126049.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            42128..43216
                     /gene="chvE"
                     /locus_tag="ACG84X_000139"
     CDS             42128..43216
                     /gene="chvE"
                     /locus_tag="ACG84X_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFP9126050.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            43270..44796
                     /gene="mmsA"
                     /locus_tag="ACG84X_000140"
     CDS             43270..44796
                     /gene="mmsA"
                     /locus_tag="ACG84X_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFP9126051.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            44798..46003
                     /gene="mmsB"
                     /locus_tag="ACG84X_000141"
     CDS             44798..46003
                     /gene="mmsB"
                     /locus_tag="ACG84X_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFP9126052.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            46260..47237
                     /gene="guaC"
                     /locus_tag="ACG84X_000142"
     CDS             46260..47237
                     /gene="guaC"
                     /locus_tag="ACG84X_000142"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFP9126053.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            47501..48925
                     /locus_tag="ACG84X_000143"
     CDS             47501..48925
                     /locus_tag="ACG84X_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFP9126054.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(48967..49224)
                     /locus_tag="ACG84X_000144"
     CDS             complement(48967..49224)
                     /locus_tag="ACG84X_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126055.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            49386..50495
                     /gene="pdhA"
                     /locus_tag="ACG84X_000145"
     CDS             49386..50495
                     /gene="pdhA"
                     /locus_tag="ACG84X_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFP9126056.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            50498..51475
                     /locus_tag="ACG84X_000146"
     CDS             50498..51475
                     /locus_tag="ACG84X_000146"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFP9126057.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            51500..53143
                     /locus_tag="ACG84X_000147"
     CDS             51500..53143
                     /locus_tag="ACG84X_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFP9126058.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            53151..54557
                     /gene="lpdA"
                     /locus_tag="ACG84X_000148"
     CDS             53151..54557
                     /gene="lpdA"
                     /locus_tag="ACG84X_000148"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFP9126059.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            54719..54994
                     /locus_tag="ACG84X_000149"
     CDS             54719..54994
                     /locus_tag="ACG84X_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFP9126060.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            55000..55767
                     /locus_tag="ACG84X_000150"
     CDS             55000..55767
                     /locus_tag="ACG84X_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFP9126061.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            55935..57764
                     /gene="typA"
                     /locus_tag="ACG84X_000151"
     CDS             55935..57764
                     /gene="typA"
                     /locus_tag="ACG84X_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFP9126062.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            58025..59797
                     /gene="recQ"
                     /locus_tag="ACG84X_000152"
     CDS             58025..59797
                     /gene="recQ"
                     /locus_tag="ACG84X_000152"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFP9126063.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            59911..60213
                     /locus_tag="ACG84X_000153"
     CDS             59911..60213
                     /locus_tag="ACG84X_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFP9126064.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            60216..61379
                     /locus_tag="ACG84X_000154"
     CDS             60216..61379
                     /locus_tag="ACG84X_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFP9126065.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            61405..64833
                     /locus_tag="ACG84X_000155"
     CDS             61405..64833
                     /locus_tag="ACG84X_000155"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFP9126066.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            64854..65978
                     /locus_tag="ACG84X_000156"
     CDS             64854..65978
                     /locus_tag="ACG84X_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFP9126067.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            65959..66405
                     /locus_tag="ACG84X_000157"
     CDS             65959..66405
                     /locus_tag="ACG84X_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFP9126068.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            66389..66727
                     /locus_tag="ACG84X_000158"
     CDS             66389..66727
                     /locus_tag="ACG84X_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFP9126069.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            66846..67406
                     /gene="rsmD"
                     /locus_tag="ACG84X_000159"
     CDS             66846..67406
                     /gene="rsmD"
                     /locus_tag="ACG84X_000159"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFP9126070.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            67403..67894
                     /gene="coaD"
                     /locus_tag="ACG84X_000160"
     CDS             67403..67894
                     /gene="coaD"
                     /locus_tag="ACG84X_000160"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFP9126071.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            67884..68927
                     /locus_tag="ACG84X_000161"
     CDS             67884..68927
                     /locus_tag="ACG84X_000161"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFP9126072.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            69086..69814
                     /locus_tag="ACG84X_000162"
     CDS             69086..69814
                     /locus_tag="ACG84X_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFP9126073.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            69930..70175
                     /locus_tag="ACG84X_000163"
     CDS             69930..70175
                     /locus_tag="ACG84X_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFP9126074.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            70172..70390
                     /locus_tag="ACG84X_000164"
     CDS             70172..70390
                     /locus_tag="ACG84X_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFP9126075.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            70526..71065
                     /locus_tag="ACG84X_000165"
     CDS             70526..71065
                     /locus_tag="ACG84X_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFP9126076.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            71058..73331
                     /locus_tag="ACG84X_000166"
     CDS             71058..73331
                     /locus_tag="ACG84X_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFP9126077.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            73369..74415
                     /gene="holA"
                     /locus_tag="ACG84X_000167"
     CDS             73369..74415
                     /gene="holA"
                     /locus_tag="ACG84X_000167"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFP9126078.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(74504..74758)
                     /gene="rpsT"
                     /locus_tag="ACG84X_000168"
     CDS             complement(74504..74758)
                     /gene="rpsT"
                     /locus_tag="ACG84X_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFP9126079.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(75158..75427)
                     /locus_tag="ACG84X_000169"
     CDS             complement(75158..75427)
                     /locus_tag="ACG84X_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126080.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(75689..75817)
                     /locus_tag="ACG84X_000170"
     CDS             complement(75689..75817)
                     /locus_tag="ACG84X_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126081.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(75897..76352)
                     /locus_tag="ACG84X_000171"
     CDS             complement(75897..76352)
                     /locus_tag="ACG84X_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFP9126082.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(76490..78418)
                     /locus_tag="ACG84X_000172"
     CDS             complement(76490..78418)
                     /locus_tag="ACG84X_000172"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9126083.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(78615..79448)
                     /locus_tag="ACG84X_000173"
     CDS             complement(78615..79448)
                     /locus_tag="ACG84X_000173"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFP9126084.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(79640..80344)
                     /locus_tag="ACG84X_000174"
     CDS             complement(79640..80344)
                     /locus_tag="ACG84X_000174"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFP9126085.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(80367..80993)
                     /locus_tag="ACG84X_000175"
     CDS             complement(80367..80993)
                     /locus_tag="ACG84X_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFP9126086.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            81319..83694
                     /locus_tag="ACG84X_000176"
     CDS             81319..83694
                     /locus_tag="ACG84X_000176"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFP9126087.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(83718..84209)
                     /locus_tag="ACG84X_000177"
     CDS             complement(83718..84209)
                     /locus_tag="ACG84X_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFP9126088.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            84396..85316
                     /locus_tag="ACG84X_000178"
     CDS             84396..85316
                     /locus_tag="ACG84X_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9126089.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            85470..85814
                     /locus_tag="ACG84X_000179"
     CDS             85470..85814
                     /locus_tag="ACG84X_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFP9126090.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(86004..86504)
                     /locus_tag="ACG84X_000180"
     CDS             complement(86004..86504)
                     /locus_tag="ACG84X_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9126091.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            87032..87115
                     /locus_tag="ACG84X_000181"
     tRNA            87032..87115
                     /locus_tag="ACG84X_000181"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:87066..87068,aa:Leu,seq:cag)
     gene            complement(87439..>87873)
                     /locus_tag="ACG84X_000182"
     CDS             complement(87439..>87873)
                     /locus_tag="ACG84X_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFP9126092.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        28296 a        15343 c        18794 g        25440 t
ORIGIN      
        1 aatcacttta cataagtttc aaaagtttct ttaatttcct attgttcaat aagtaacaat
       61 gtaaagataa aattaaaaat gttaatacgt attagcaaaa taaaagcttt ttttattgtg
      121 aataaatgaa cataattagg aggagaaaga tgaacttatt tgacattttt cgatcgactt
      181 tgacagatat gtcgattgtc agtgcaatca cttcaacagt ttttattata ttattagggt
      241 ttgtttgtag aaaaaagggg attttttctg aatctgttgg aaaaattcta tcgaaagtcg
      301 tcttaacagt ggctttgcca gcactggcat ttcgagcttt catgcaagat atcaatacag
      361 aattactgat gcaaggaatc aatgtcttga tttggggatt agttatttat attattctta
      421 ttctagtttc aaaacctttt ttcttaagct ataaagggga taagcaaaca acgttgcgtg
      481 tcctgacgat ctttggttct acgacctttt tcggaacgcc tatcgtcagt gcgatttatg
      541 gtcctgtcgg cgtgatgtat tcctcaattt tcaatattgg ctaccgaatc tttttgtatt
      601 cttatggata cataaaaatg agtggcttga agatggaagc taaaaatatc aaagcgatgt
      661 tcgtcaatcc aatcattatc gctacttttg ccggcctttt catttggctg ttccaagggt
      721 atctgccaca agtgtcagtt acaggtgcag aaggagagat aagccaagta gcgtttttgc
      781 gaattgacca gactgcaccg tggctatttc agtcgatgga ttatttagct ggtttaagtt
      841 caccattggc gtggctagca atcggcgcaa cattaggtga agtaagcttc aaaaaagctg
      901 catctgaaaa aacttcatgg tattacagtc tagtcaaagt ggtatttgta cctgcattga
      961 atatcgtgat tctagcagtt ttgacggcaa cgaatattct accagtcaat tttgaagcac
     1021 tggcaacaat cgttatcatg atggctacac cagctgcaac agtggcagca gcctatgcta
     1081 tcagttttga tagggaggca cttttagcct ccaatgcatc cttactgtca actatttttg
     1141 ctgtggtact gacacctgta tggatcgttg tattacaaat gattcatggc ataggtttat
     1201 tttcataaga aatggaggaa gaaagtatga gaatcgcatg ttacggtgtt cgtccgaacg
     1261 agatagattt ttttgaaaaa ttgaatattt accattatga tctcagtctt tatgaagaac
     1321 tgttgacaca tgacaatatc gtgtcagcaa aggaccatga tgctgtattg ttgaggggaa
     1381 attgtatagc agatgagacc aatcttgcaa aaatgcagga atatgggatt cgttatgttt
     1441 ttacacggac tgtgggagtc aatcatatcg atctacaagc ggcagctgat tttggtatga
     1501 cagtagcccg tgtaccatcg tattcgccaa atgcgatagc agagttatct ttgacttttg
     1561 ccatgatgct tttgagaaat actgcgtata cgacgatccg aacatctttc aaagattttc
     1621 gagtggatga gcaaatgttt agtcgtgaaa tcagaaattg cacagtaggg atcataggaa
     1681 caggcaggat agggttgacg gaagctgttt tgtttaaggg actaggagcc aaagtgatcg
     1741 gctacgatat tcatcagaca gaagctgcta aaaaagtatt gacgttccac tcgcttgaag
     1801 agttattagc caaaagcgat attgtcagta ttcatgtacc tcatatccca ggtgaaaacg
     1861 atcaaatgat caatgaagga tttttagctc aaatgaaaaa aggtagcatc ttgattaata
     1921 cagcccgtgg agagcttcaa gataatgaag ctattttaag agctttgaaa agcaatcatt
     1981 tagctggttt tgcaaccgat gtttttgcaa atgaaacaga ggtttttttc cgatccttca
     2041 agccatggga gacgattcca gaccctgcta tccagcaatt agtagaaatg taccctagag
     2101 ttcttgtaac cccgcatgta ggttcaaata cagatgaggc attatcaaat atgatttcga
     2161 caagtttcga gaactttcgt gaaataatag aaactggaaa aacgaaaaat gaggtatctc
     2221 ttcctaaagc ccgtcaatta agataagaaa acatggatat tcgtcaataa aatgtttaaa
     2281 aatagtccaa gtaaacagtt gttacttctg tatacttgga ctattttgta tgggataatt
     2341 cgatgactca acagtaatct gtgagctttt tccgcccatt ctttgtcaat tcataacagg
     2401 ttagcggccg gccgatttcc aaatatttga ttctttcgtt caatatatct tgttctacta
     2461 aaaaattcaa atatttcttg acggatatac gtgacagtga gcttttttga gccagttctt
     2521 ttgttgaaaa aatagtatct tcttttagaa taaatgcact tatttttttt aaagtcagtt
     2581 ttgacagacc tttaggcaaa tcgatgaatg atggtatttc gtgaatggga gtggtgtggt
     2641 tgaatacttg atcgatcaat ttctgatcgg ctttttcagt cgtttggatt gtctgagaga
     2701 aagcaagata cttttcgatc gccagctgaa aacgttgcaa agtgaacggt ttgatcaaat
     2761 aatctaaggc accgtagcgg atcacattct ttatggtttc gatatcatct gcagcagtga
     2821 tcaaaatcac tgggatatca tttccttgct gtctaagcca agataaaaaa tggataccac
     2881 tttcgccagg catgtataca tcaagcagca gcagatctgc gtttttttgt ctgaaatatt
     2941 tttttccttc ttctacattt ctgaaacttt cgattacgtt catattaggg atgctttcca
     3001 caaaagtacg attcaattct gcaaccattg gatcatcttc gattatcagg acatttgtca
     3061 tcattttgat cttccttttt tggtaattct agatagacga ttgtaccgcc atttgtttgt
     3121 ttggaaaatt ctaaaaatcc accgtggcgt ttgacgattg aatggatgag attcaatcca
     3181 aacccacgat tgattccctt cgtcgaaaaa cctagcgtaa atattttttc tgagatttct
     3241 tctgatatcc cgacaccgtc atcgcagacg gtcacgatga atacttcagc ttctgtgtca
     3301 tagtttaaat gaatccggac ctgtccgttt ctttcatgtt tttgtagcac ggcttctttt
     3361 gcattatcaa gtaagttccc taacacttgc aaaagtgaat ggatggagtc atccatctcc
     3421 attttaggga taaaagaatc gctttctaac agcatttcaa cagattgttc tttggcttcg
     3481 tttattttgc ctaataaaaa accggcaatt gcaggtactt tgatcagact tgagacttgg
     3541 ccaatctctt ttttataatt ttgatttagc tgctggataa aatgggtgac ttcttcatac
     3601 ttcttcaaat caatcaaacc agaaatgaca tgaagtttat tcatgaattc atgggtttga
     3661 gctctcatgg agtttatata ttgtttcgtc cccccaagct cctccattaa tttcattact
     3721 tctgatcgat ttcgtaaagt tgcgactgct cctaaaaaac ggtcattgct aaaaagaggt
     3781 gtaacgctag aaatagtttc tatcccattt aaatacatgg attgagtccg aacggtcgtt
     3841 tgatgctcaa tcgtctcttt aaacaaaacg tcatatagat tatcactgat ttttttccta
     3901 cttcgaaatc caatagctgc tctgtttggt agaaaatgtt ttttgcaggt gtattgatca
     3961 agaggatagt tttatcagaa gagatggcta agattccttc atctacttca ttttcgataa
     4021 tcgttttttc acttaactgt tctgctattt cttgtggttc aagtccaagc agtacttttt
     4081 tcattttttg ggcaagaaaa acggcgccta tgatgcctac gctaagtcca ataatcaatg
     4141 aaaaaacaat cattttttgt ccatctttga cttgattgtc aatcgtgttg tttgttaagc
     4201 caacacaaac tgcaccaata atctcttgat cataataaat agggacgaaa tagcggaagc
     4261 cgaaccctaa cattccttct ttttcagaga aaaattcttg tcctccaatc acttttttca
     4321 catcttcatg acttgagaaa ggaagaccga tgtaacttgg gtctgcgtga gaatatcgaa
     4381 tgccttcagg gtccatgaca acgataaaat ctaaattcga tgcaatcatg atttcatttg
     4441 ttattccttg aatcgcatgt gtcgggtcac cagtctgcag ctttttttgg atgagtttat
     4501 cattggcaac gattttagca atgctagaga ttttatctga cacactagat cggttcatcg
     4561 aaagaataaa attcctgatc aatatggcag aaacaatcaa agaaacgaat gtggagaaac
     4621 aaacgacaag gatgatcgtg ttctggagct ttaatggttt tttcttaaaa aaaggaaaca
     4681 taggctacct cgaaagaatt tattgtgaaa attttaacat gaaaacaaaa atttaacaaa
     4741 ttgtcaacga taaacacaac cttcctataa aaaacaccac tgagtcggta aaagaagcta
     4801 tacagaattt tcaaacattg gtatgataga cgtagaaatg gaaggaggcg tgtatatgat
     4861 agggggaatc gcacttgaga cgatttattg gtatacattg ctgatttgtg caggattggc
     4921 agtcctattg attatttttg gagatgtatt cgattttgat ggcccgcttg atccgatgct
     4981 tattatccct tggttaactt tcacaagctt atttggtttt ctaggtgagc gtttaacaga
     5041 tcaatcatct ttatttttat ttattgctag tggaggcata tcgatagtgt tggtattttt
     5101 gcttaatttc tatatattga tgccgatgaa acatgccgaa tcaacgatgt cgtcttctga
     5161 aaaaactctg gaaggacaag tagctgttgt gatcacaccg atccctgtac gaggtatggg
     5221 agaaattcag ttgaaaagtg ttaccggttc cattagtcgt ccagcttgtt tttacagccc
     5281 ccaagaacag acagctgagc ggggaacgaa agtattgatc attgagatca aggaaagaat
     5341 ctgttatgtc atgccttatg aaagcatgat aaaagcttaa aggagcgtgt gttaaatgga
     5401 aataccagtt gtttttatcg cgatcgcaat cgcagctttg attttactga tgttgctgat
     5461 cgtctttgta gcgaagtacc agacagcaaa accggatgaa gcgttgatca tcagtggaag
     5521 ttatttagga agcaaaaatg tgcacattga tgaaagcaat aacaaaatca aaattgtgcg
     5581 tggaggtggc gcattcgtct tgccagtttt tcaacgttcg aatcggatca gtctattatc
     5641 gagtaaattg gacgtctcca cccctgaagt gtatacggaa caaggcgtac cggtgatgtg
     5701 tgatggtact tcgatcatca aaatcggttc atctgtagaa gagattgcta cagcagcaga
     5761 acagttttta ggcaagacaa gagaagaact ggaaaatgaa gcaagagaag tattagaagg
     5821 acacttgcgc tcgattcttg gttctatgac tgtagaagaa atctatcaaa atcgcgataa
     5881 gttcagtcaa agcgtacaag aagtcgcttc tgtagacctt gcaaaaatgg ggttgatcat
     5941 cgtttctttc actatcaaag aggtcagaga caaaaacggt tatcttgact ctttagggaa
     6001 accaagaatc gcccaagtca aaagagatgc agatatagca gaagcggaag ctctaaaaga
     6061 aacgcgtatc aaaaaagctc aagcagaaaa agaatcacaa gcagctgaat tacagcgaca
     6121 aacagagatc gcagaatcat taaaagaaaa agaactgaaa ttagcaacct acaaacaaga
     6181 acaagatgtt gctaaagcaa aagcagacca agcctacaat ttagaaagtg cccgagcaca
     6241 acaacaagta atcgaacagg aaatgcagat taaaatcgta gaacgtcaaa aacaaatcga
     6301 actggaagaa aaagaaatca cacgtcgtga aaagcaatat gattcggaag tgaagaaaaa
     6361 agcagatgcc gatcggtacg ctaaagaaca agaagcacaa gctcaaaaag tcaaagaagt
     6421 gactgaagcc gaagcagaac gattccgtgt ggaagcactg gcagaagcgg aagccaataa
     6481 gacacgttta gctggacaag cagaagccga agcagcacta gcaaaaggaa aagcagaagc
     6541 cgaagcaaaa caaaagatcg ccaatgcctt caaggaatat ggcgaagcag ctgtcttgag
     6601 tatggttatc gatatgctac cgcaattgat gcgcgaagca gcacagccgc taggaaatat
     6661 cgaaaaaatc tctgttgtcg atacaggaag cagttcagga gaaaccagtg gagcgaaccg
     6721 agtgacaaat tatgccacaa atttgctttc ttctactcaa gaaacactaa aagcgacaac
     6781 aggacttgac ttgaaggaaa tcgtagagaa tttgtcgaca cgtgggacta ctagccaagt
     6841 aaatatgtat gaagcgccaa aagaggcaga acaaaactcg atgaaggaag aataaagtag
     6901 tacacttcac cgttcaatca aaaatggagg aagacttttt aaagttcttc tctccatttt
     6961 tttattttat tgcaaaagaa aattagtcct cgctattttt cttttgtttt tggatcttag
     7021 cttctatctc ttgtaaattt gttcttagca atcgttcttt cttttggagt tcgaccaaat
     7081 cttctgatag ttcttccttc ttttctgttt caggaggacg aagaaagaaa ttgataccga
     7141 ttgcaatgaa tgtccctata aaagtatcta gtacacgttg gatagcatac aaagcggatt
     7201 cgccttgagg gatgctcaac gcaatcagca acaacgtagc tattgcggaa atgataccgg
     7261 aattattgtt aataccatct gacacgacga tcacaataat aactagaata ggaagcaaga
     7321 tcaattctac caaaaaatca ttgtgaaaat agcttttgac aaaaaaataa atgatagcta
     7381 atgtaccacc taatgtattg ccgatgatcc tagactttcc aaaagaaacg gttgtagtca
     7441 agtcctgacg caaagaaaaa acagcagata atgcagcaat catcgggatt cctcgttgag
     7501 tcaaatgaaa aaacaagata cataaaaaaa cagctaaggc acttttgatc gtacgcatac
     7561 ctagtcgaaa acggccaaat tgcatagaga ttctcctttt tggtcttttt actatcatac
     7621 ctaaactttt gtctgatagc tagtttttca ttattcaagt ataattaaaa taaaaaaggg
     7681 ggaagtaaat gcgtatagga atgcgaacag tcaaaacagt gatcagtgtc ttcttttcga
     7741 tggtcacagc gggtagctta tcgctgttgt attggccagc tgcagggatc attgcattat
     7801 taagtgtagg aaataccaag cgctctacat tgcgtacggg catgaatcga atcgcagcct
     7861 ttatattagc tacggcaaca gcactgttca gtttttttgc tgttgggtat actatttttg
     7921 gcttcagtct ttttttattc ctgttcatcc cgcttgcctc tcgcttcaaa ttaaccgaag
     7981 ggatagtagt aaattcggtt ttggtcactc attatttagt ggaggaaaac atgtcttggc
     8041 agctgatcgg caatgaagcg ggattaatgg cgattggatt agtatttgct ttgcttgcaa
     8101 atgtttacat gccagatcgt acgaagcagc tgaaggaaaa ccaaatacag atcgaaaaag
     8161 aatttcgaaa tattttgaga caaatggcag aatttctttt atcagaaaat aaagaagatg
     8221 tgcagatcaa atgcgaacat ttactgacat tcattcgcga aagccaagaa gatgccagag
     8281 aacatcaaga aaactactgg ctcagacagc cgctatacta cgaaacttac ttctctatga
     8341 gaagagcaca ggccaatgtg attaaagaca tgctggaaaa tctagagaga atccagcaac
     8401 cagcttatta tggaaaacat atctatggtt tattgattta tactgcagaa acattttcag
     8461 agtcaaatga tggcagacaa attttaacac gtattgaaga agtttatgta ttgtatcggc
     8521 aaatgcctct gccgactagt cgccctgaat tcgaggatcg agcagaattg ttccagtttt
     8581 tgcagtcttt taaaagtttt attgaaatca aggcagaatt ctcccaacaa aaaatccaaa
     8641 aatagaggtt gtgaattcag ctaatattca ggtcaaaaag ctgatttcac aacctcttct
     8701 ttaaacggtg ttctcctgtc aactcctcgg tcacaagtca caatattcaa caaacatgag
     8761 aagctgtttt ttgaaattgc tccttgtgac tcggagctga acggtaggct cacaacctct
     8821 ttcttaaacg gtgttcaaaa gctttcctct gcggtaataa gtccagccaa acgaaaaata
     8881 ggaggagcta tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac
     8941 cttttaaaat tacatatttt tccatagaac ttgcatttga tccaagattt cgatgacatc
     9001 ttttgtcaag aagagagagc gattgggcaa gtcaccttca atcatgtgta ccatattctt
     9061 tatttcgtaa ttcattgctt cagatgtatt cccgctttcg atgaattcct ttgtaccatc
     9121 tgtaaataag atctccgcac gatcagcacg cgggtaatca gcaatcgtca cataaccgtt
     9181 ctcaaaggca acgataccga cttttggcat ttttgcctga aaagtcaagc tgacagcagc
     9241 aagttcattt tctttgttac gcaagatagt gacggattgt tcgtccacgc ctgtttcaaa
     9301 aggaaccatt gtagaggcaa ctacttcagg ttgagagctc aaaaagaaac gagcgaaaga
     9361 tacagcatac gtaccgatat ccaacagagc tcctccagct aattctggat tgaagaaccg
     9421 gtttttaggg tctggttctt tgtaactgcc gaaaggtgct tggatcattt ttaaagcccc
     9481 cagttttcct gtatccatta ttgagcgtaa ctgctgataa agtggcatgt tgaagattgt
     9541 catcgcttct gctaagatca aattcttttc ttctgctaag cgcatagcgt cagccagttc
     9601 ttttttattc atcgtgatgg ctttttcaca tagaacgtgt ttgcctgctt ccaatgctgc
     9661 caagatatgg tcgatatgct gtctatttgg tacagcaatg tacacgatgt cgatttcagc
     9721 atcgtctaac atttcttgat agcttccgta agcttttgga atattgtaac ggtgagcgaa
     9781 gttttccgct ttttctgaag ttctggaagc aactgctgtt agttcgctcg tctcttgatt
     9841 gaagctttcg gcaaactcat gtgcgatggt accaagacca acgattcccc attgatattt
     9901 tttcatctga aaacgctcct tcatagttgg attgagtttc ttgtctgtct attattataa
     9961 caaaaatcac gaagaataaa gaggagagga cttgaaacat taaaaaaaat gaaagcagcg
    10021 atttaagagg tgctttttga tcaaaactta agtagaatag ttaaaaggag gggataaacg
    10081 tgcatcaagt atatattgat cttattatga gtgtattatt agaacagttt gaaactgaaa
    10141 aaaatttttt agatgaatac ttgctgatca gtccagaaca atggcaaaaa tggaaagatg
    10201 gcgagaaaaa tctgccatct gaagcgatgc agaaagtaaa aaatcttttc actgattatg
    10261 aatggatgct aacgcaaaag attttgcgtc aaacgattat ttttcccgaa aaacgaaacg
    10321 ttgccgttgc agagtacaag caaatcaaaa cacgcatcgc gcaaaaatgg cttagcagca
    10381 aagcagcaaa agtcgagctg atccctttga aaaataatca gcaggctggt agataccttg
    10441 acttgaaagt aagtattcaa tatgatgaat ggggctatga tgatattttg aattttcgtc
    10501 tgccagcaga tgttcaaaaa cagatcgaag gagaaaaaat cgaacttctc gattgggtga
    10561 atgaaaatct ggaagaaact tacgttcatg aggcgaatgg ggaacgtgaa gaacaacgaa
    10621 aggatttttc aagtgaataa atttttagga tttggagcag ttgtgattat gatcgcagca
    10681 atgggctatg ttatttttag cgatgatgat tcgcatgttc aagccggcaa tcaagcagtc
    10741 gaacgaacaa gcaccaaaac aactgctagt aaagaaaaga acagtcaaac aaccagcagc
    10801 aaggtaaagg acaaagaaac aaaagatcgt acgtccaaac aattgccaga tgttaaaaca
    10861 gacgattgga agctagtttt ggttggtcca gatcacaaat tagaaaaaga aattgatgag
    10921 tctactcaat tggcatcatt aagtaacgga tacttgatcg acaaacgcat tgctccagaa
    10981 tatgaagcat ttgccaaggc tgctgaagca gctggatttc cattagtgat ggtctcagct
    11041 taccggtctg tatcatccca acaacaagtt ttcgaacaaa atgtccaaga tgtgatgagt
    11101 cgtcaaggtg tatcagaaga ggaggcgaca aagattacta aagaaacgat tacggagcca
    11161 ggatacagcg aacaccacac aggtctggca gtcgatgtcg tcgatcaaaa ctggtacaac
    11221 agttatcctt ctactgtatt ggatgcaagt tacggagatc agcctggagc taaatggatc
    11281 gcagataatg ctgcgcagta tggatttatc gttcgttatc caaaaggaca cgaagatata
    11341 actaagatca catatgaacc ttggcactta cgttatgtcg gtaaagaaaa cgctgagtat
    11401 atcaccaaac accaattgac gctagaagaa tatctgaatg aattaaatga aaagtaggaa
    11461 ttgatcatgg cgaaaaaaaa gtggaaaaag caaaagcgca agaatatccg ttggccagca
    11521 gtggttgccg gtgtagcagt gatactctta gcctttgttt tttccttgaa gaatctgtct
    11581 tctcctttta ctgataatca gcaagaaaat gaagcgcaat cccatcagca atttattgaa
    11641 cggcttgttc cgcatgccca agaactacaa gatggttatg gagtgcttcc tagtatcatt
    11701 ttaggacaag ctatattaga atcaaattgg ggaaaaagta ccttggctag caaatacaat
    11761 aatcttttcg ggatcaaggc ttatggggat cagaagaaag taagcctgga aacaaaggaa
    11821 tttgttaacg aagaatggat aactatccaa ggagacttca aagtgtatga ttcatgggaa
    11881 cagtccatgg atgaccatac acaactgttc gtccaaggag tagattggaa tcctgcgctg
    11941 tatgaaaaag tgattacggc caccaactat caggaagccg cacaagcatt gcaagatgca
    12001 ggttatgcga cagaccccgg ttatgcgcaa aaaatcatcc aggtcatcga gacgtatcaa
    12061 ttgaatcagt atgaccggag atagcaaagg agaagtggct gatggcagaa caatttacgc
    12121 cagaaatcat gacggaattg agaaaagata tcgtaagagt accggaaatc attttagaag
    12181 caagcgggat caagatattt ggaaaattga tccgttcgat catctttact acggatattg
    12241 cgatcatacg taatacaaat gcgaatgcag taattgctgt gtatcctttt acacctcatc
    12301 cagcgattac taaaagcatt attgaggcag ctgacattcc agttttctcc ggtgtaggtg
    12361 gtggtttgac acaaggtgct cgttcttcct acatgagcat gttcgcagaa gcgcaaggtt
    12421 cgttaggggt cgttttgaac ggtcctacgc ctttagagac agtaaaagaa gtttgtcgag
    12481 tagttgatat tccagttatc agtacggtaa cgtcgaaata tacagaaata gatgaaaagt
    12541 tagcagctgg tatttcgatt atcaatatca gtgcaggtaa agaaactgca gaagcagtac
    12601 gccattttcg taaaaaatat cctgaacttc ctatcattgc gacaggtggt ccaacggaag
    12661 aaagtattgc tgagaccatt caagcaggag caaatgccat cacatatacg ccaccaagta
    12721 gcggagagct ttttagtcgt aaaatggaaa aatatcggga aactgagaaa aagaatcatg
    12781 aataacaggt gagaatcaaa agacgaggaa gagcagatag tggctcttcc tcgtcttttg
    12841 tactccagta ctatttgttc agaattcaaa aaaaagagaa atttttttgt ttttttacct
    12901 gtaatgtaca taagaagagt taaaaccttt tgttattatt agcattctaa caaaaaaatg
    12961 tcttgattta ttgaagcgct ttctatagaa tgaaaaacga ataaaaacta aaaaaggcac
    13021 ccgacaattt agtagcagct aaattgtcgg ggcttgaaaa gtcagcggga actgaccaat
    13081 caagttgcca tagtcaatgc ttgtgcatcg acgtgtatat tgtacctaat ttcatacaga
    13141 attactagtt atttttctgt tttttaggga agagcgcaca cgaagaagca tgcttattta
    13201 gctatgtcaa ggatattggg cagttgtctg atatcctttt ttctttgcgt aattatcctc
    13261 ccatcattga agcaagaagt gtttttagcg atgaaagaag aatcagcact atctaatttt
    13321 tcttgaaagt attgagttgt tcatcctagg cagaacgata aggcaagtct tggtttttat
    13381 tccccttgaa aaagatcgtt taataaatat gttctgtata aaaatacagt atattgaaaa
    13441 ataacaatgg aagtagaggt gcagagaatg aagaaaagaa tgagaatcat cttagcttta
    13501 agtgttatgt tattcttctt gacggcttgt gggcaagaag atgacaaaaa aatcacgctg
    13561 aacatggctt ggtggggttc gcaagtccga cacgatgcaa cagtaaaagt aatcgagctt
    13621 tatgaagaaa aaaatcccca tgtgacgatc gattatgaat tttatgatta tgaaggatat
    13681 tacacaaaat taggtacact agcagcatca gatgatatct gggacatttt ccaactgaac
    13741 aatcaatttc ctcaatacat caatcagatt gaaccattag atgaatatgt ggagcaaggg
    13801 ataattgata tttctaatgc agatgaatcc tatttagcaa cgacgactta cgacgggcaa
    13861 ttagttggac tgtctaacgg ggtgaattcg tttgcgattg cttacaataa aaatatattt
    13921 gaacaattaa atatccctga accagcttca aattggacat gggatgaatt tgaacaaatc
    13981 agctatcaaa tcactgaaga attaggaatc tatgctattt caagattcga agattttata
    14041 gctggctgta ttattcaaat accacaagtt gagaaaggat tgaattttta taatcgggaa
    14101 gatctatcta acagcttggg atttgaaaat ccagactatc taacagattt tttccagctg
    14161 cgtaaaaatc tggtagacaa aggggcccat ccagaaccag gtggtggagc tgcaagtacg
    14221 acggatctgt cttttcaggc ggttagggat agagaagcgg caatggtgtt tctatcaagt
    14281 aaccagttga cagaaatatt gtcaggggct cctgaagata tggagattca gttgattaat
    14341 ccacctcgca gaaaagcaga tggagaatct ggtatccctt tacgttcttc gcaaatgctg
    14401 agtatggcaa aaagctcagc ccataaagaa gaagctgcta agtttattga tttctttcaa
    14461 aacagtgaag aagccaatga aattttaaaa ggagaacgtg gtgtaccaat catgtcgaat
    14521 attcgagaac agctcgctcg tgcagatgat gcaactttgc aagcgacatt tgattattta
    14581 gaaatgattt ccgatatgga caacggcgaa gtgaatgtct ttgatagtgc tttgaatccg
    14641 gaaattcaag accaatacaa tcttttagtt gaaaaagtca tttatgaaga agtaacagca
    14701 gaagaagcag cagagagtct ttatgagttt gcgtcaaaca ttctaggata gcagcaggag
    14761 gaaggcatga aaaaagaaaa actaaaacgg ttcttggatc aagacaatgt ggtcggttac
    14821 gtatttgctt ctccattcat cctaggattt ctattgataa cagtgatacc gatgatcttg
    14881 tcactttatt attcgttcac cgattatcgt ttgggaaatc cagtctcatg gatcggcttg
    14941 gataattata taaagatgct gagtgatgcc cgttttttga actccatccg agtcactttt
    15001 ctctatgtat ttgcatctgt acctgtgaaa ctgatctttg gtctattgat tgcttatctt
    15061 ttaacgagga atatcaaagg aacgactttc tttcgttctt tgtattatgt gcctagtttg
    15121 atcggtggca gtatttctat cgctctagtt tggcgggagt tgttttctaa aaacgggtta
    15181 gtgaatattt tcctggaacg attaggcgca cctgcgcttt cctggtttag cgatcaaaaa
    15241 ctggtcatga tccctcttgt tttgatgtct gcttggcaat tcggttcggc aatgatcatc
    15301 tttgctgcag gtatcaaaga gatcccaggc tcgtattatg aagcggcaga gatcgatgga
    15361 gcgaacaaat ggcagacgtt ttacaagatc acgttacctc ttctttcgcc gatcattttg
    15421 tataacttgg ttatgcagac aatcgcggcg tttatgactt ttacgcaggc atttatcatt
    15481 acccaaggtg gtccgaatga tgccacgaac ttttatgctc tttatgtgta taaccaagct
    15541 ttttctttta attctatggg gtatgctagt gctatttcgt ggatcatgct gttgattatg
    15601 ggagctgtca cctttctgat tttcaaatca tcaaaaaaat gggtcgttgt gtgaatgaga
    15661 ggaggaagaa atgaataata cagtaacgaa atggtttcaa tacggtttta ttttgctatt
    15721 aggtctagtc atgatttatc cggtcttatg gatgatcgca ggttctttta aaacggatca
    15781 agagattatg agtggttcgc tgaatttgat tccagagact tttcaatggg aaaattacgc
    15841 aaaaggatgg gcggggtttg ctggaatttc attttttact ttctttagga attcgtttgt
    15901 catctctgca gtttcgacga tagggacagt tctgagctcg acttgtattg cttacgcatt
    15961 atcgagaatc gatttcaaag gaaaaagatt ctggttcgtc gtcatgttag taacgatgat
    16021 gattcctgca caagtgattt tgattccgca gtttattatt tacaatcggc tgaatttggt
    16081 tgggacgtat gtgccgctga ttttaccaca tttttttgga caagcatttt tcatttacca
    16141 gatcatgcaa ttcatggtca gcatccccaa agagttagat gaatcagcga ttattgacgg
    16201 atgcagcaag tatagtgtct ttaccaaaat tatttttcct ttgctgaaac cttcgatcat
    16261 cacgacgatc atcatccagt tttattggaa atgggacgac ttcatgggac cattgattta
    16321 tttaaacaag ccgagatctt acacggtatc gattgccatc aaattatttg cagacgctgg
    16381 atctagtacg acttacgcga gtatgtttgc gatgtctacg ttgtcgctgc taccggtttt
    16441 tctgattttc ttattcttca ataaatatct tgtccagggg atcagtacaa gcggtctgaa
    16501 gggctgaata tgaaaaagcc aatagaagag atgtttcttt acaagctcaa ctactatgtc
    16561 tgtcggattt ttttaaccag tcttatcagt aatgctcttt tcgctttagt tctaggatgt
    16621 ttgttcactt taggattagt gctgtctgct cgtgttgtct atctgattta ttttttgatg
    16681 atgtatcctt cttattatct atctgtccat tacttggcag aaaaaaaggt atgttggagg
    16741 aaaggaaaaa tcaaacggat gtgtttcatc attacgttgt ttcagctgtt tgtcattatt
    16801 tttgcagttg attggtattt attagtggga aagattggag cttggtatct gattcctttt
    16861 ctattgtgtc tgttgctttt tgtatcccat agttttttta gtacgctaat tgatatctgc
    16921 aaagaagata aagcagatag tcttgtttat ttgatcaaaa ggaatatctg gctgttgtca
    16981 aaaaacgtca aggggtttct gtggtattta tgccttttgt atggactgtt ctggtgtata
    17041 cagcatgatt ttttactcac tgcattactg tatccagggc tgccatttgt cacagtattt
    17101 tgcttaaaag aaaaggagaa tgactttaaa tgaagaaaaa atatgtacaa gtcggacttg
    17161 gtgggagagc gcgttttttt tatgaggcaa ttgcctctac gtatcatcaa acttgtgaac
    17221 tagtcggttt ttgtgatgta tctcaaacaa ggatggatta tgcaaatcgg atacttgtga
    17281 acaagtatgg acagaaaaaa gtaaagacat gtatgccatc acaatttgag caactactgg
    17341 atgacgtacg gccggctgaa gtcattatta cgtcagtaga tcgaacgcat catgattata
    17401 tcattcgtgc aatgaaaaaa ggatatgatg ttatttgcga aaaacctctg actatcgatg
    17461 aggaaaaagc tcaagaaata ataacggtcc aaaaacagac gggaagaagc ctgcgagtca
    17521 cttttaatta tcgttatgca ccgtatcaca cgaagataaa ggaactgata gaaagtgatg
    17581 tgattggtga tgtgttttct atccacttcg aatggctgtt aaatacgcaa cacggggcag
    17641 attatttcag aagatggcat cgaaataagc acaatagcgg cgggcttctt gttcataaat
    17701 ctacccatca ttttgatcta gtgaattttt ggttgaacag ccgtccccaa aaggtatttg
    17761 cattcggtgg attaaacttt tatgggatgc ataatgcgga gaaacgcgga gtagaaatat
    17821 tttacagtcg atgctatgga agcgaactag ctaaagctga tccatttgct atagacctgt
    17881 cagccaatga ggaattgcga gaaatgtatt tagaagcaga aaaagacagt ggatatattc
    17941 gtgaccgcag tgtattttcc gatgatatct ctattgaaga tacactaggc gtaacggtca
    18001 aatatgaaac tggtgcgatt ttgacgtatt cgctaaacgc gtatatgccg tgggaaggat
    18061 tcaatgtttc tttcaatggc agcaaaggac ggatcgaaat gaaagtgatc gaaaagtctt
    18121 acatcaatgc aggtggagat aaaaaggatg aaggagcagc cgttcttcag tccatccatg
    18181 tctatccgat gttcggtgag ccatatgagg taatcgtcga acaagaagcg ggcggacatg
    18241 gcggaggaga tccgcgttta ttagatgatc tatttggtga agaaaaagaa gaagatccgt
    18301 ggaatcgggc agcaactcac gtagatggta ttttgtcgat tttgacagga atcgcagcaa
    18361 atcattctat tgcttcagga aaagcagtag tgattgacga gcttgtcagc ttaaaagaat
    18421 aagaatagat ttacggaaat tacttcccgt agtttataaa atcttgcctt attgccgata
    18481 ggctgtcttt tgaacactat ttattcggaa aaaggggcta tgacatgctt tttgtcatgc
    18541 catcttttta tgtgggctgc ttttttagat aggagaaaat aaaaataact atttaaaccc
    18601 gaacaaaaag gaataatgca ttaaaaatca ttagatttta caaaaaaata agtaaaccac
    18661 gttgtcagtt tcagaaagta gtgttagact gttttcaata tttgaaacaa cattttttat
    18721 tcaaatatgg caaactgcct tcacgtgcaa aacagttgca agaaaatgaa tttacactat
    18781 tattagtttt acatacctac ttatatatcg tcataatatg gatgacagtt tctagccagt
    18841 accgtaaatg ctggactata agtaaaagat tggctatttc acccttcttt tcttatgata
    18901 aagtggaggg tgtttttctt taacagaaac atagtaggtt tttgcacaaa agcggttatt
    18961 tcggtattaa taaatgataa aggagcaaat aaagtgaaag aattagttga acgtattcaa
    19021 aaagacggac gtatattagg cgagggcgta ttaaaagtcg acagcttcgt cactcaccaa
    19081 gtagaccctg tattgatgga acaaatggga aaacggtttg cagaagtatt taaagaacaa
    19141 ggaatcacga aagttgtgac cattgaagct tctgggatcg caccagcttt atttgctgca
    19201 agagaattag atgttccaat gatcttcgct agaaaagcaa aaagtttgac gatggatgaa
    19261 gaattattga cagcttctgt ttattctttt acgaaacaag tgacaagtac gatttctatt
    19321 tctcgtaaat ttttatcttc agaagacaaa gtattgatta tcgacgattt cttggcaaac
    19381 ggacaagcgg caaaaggatt gatcgaatta tgccagcaag ctggagcgca agtagaagga
    19441 atcgggatcg tcatcgaaaa gtctttccaa gatggacgtc agttacttga agaaatggga
    19501 ttgagagtcg tttctcttgc gcgtattgct tccttgacga atggacaagt tgagtttctt
    19561 gaggaggacg cataatcgtg gaaaaagaaa cacaaaatgg aaaagctgcg gttttagggc
    19621 tgcagcatct gctagcgatg tatgcaggag cagtagcggt gcctcttttg atcggtacag
    19681 gactaggctt taatcaagaa cagatgactt atttgatttc aattgatatc tttatgtgtg
    19741 gattagcgac attattgcaa ttgacagtta accgattttt cggaattggc ttgcctgtcg
    19801 ttttaggatg tgcgatccaa gcagtagctc cactgatctt gatcggaacc aatgaaggag
    19861 taggagctat ctacggatct attatcgctt ctgggatctt tgttgtgtta gtttctggtg
    19921 tcttttctaa aattaaaaaa ctattccctc ctatagtaac aggaacggtt atcaccgtta
    19981 ttggtttgac tttgattcct gtagcaatcg agaaaatggg tggaggtaat gcaacagcag
    20041 ctgattttgg tgacaaaaca aatctgctac ttgcatttgt gacgattctc ctaattgtag
    20101 gcgtgcaaat gctggcaaaa gggttcattc gttcaatcgc ggtattgatt ggtttagtcg
    20161 gaggaagcat cttagctgct ttcatgggaa tgattgatct gagcgcgatt ggagatgcgc
    20221 cgttgttcca tgttccacaa cccttttatt ttggtaaacc aactttcgac gtatggtcga
    20281 ttttactaat gatcatcatt tccatggtca gcatggtaga atcaacaggt gtatattttg
    20341 cacttggtga cattactggg aaaaatgttg gagaagaaga attgaaaaag ggatatcgtg
    20401 cagaaggact tgccgttatc ttaggcggta ttttcaatac attcccttat actggctttt
    20461 ctcaaaatgt cggattggtt caactttcgg gaatcaaaac aagaaaaccc atctatttct
    20521 ctgcattctt cttgattgtt ttaggattat tccctaaaat cggtgcgtta gcacaaatca
    20581 tccctgagcc ggtacttggt ggaggaatgt tagtcatgtt cgggatggtg gcagtccaag
    20641 gaatccgtat gctgttggaa gttgatttca gcaatgataa aaatctattg attgttgctg
    20701 tttctgttgg atttgggctg ggtttcaatg ttacgccgac attattcagt caaatgccgc
    20761 aaacattgca aatgttcact ggaaatggca tcgtaatgag tagcattacg gctatcatat
    20821 tgaatttgat ctttaatgga ttgaaaaaag atgaagaaat attggaagaa gccttcaaga
    20881 agtaatagag caaaagaaag gttgtgaaat cagcgttttg acctgattgt tagagaaaca
    20941 aacggaaaaa tagttcctcg tattttgccg tttgtttgag ctaataccga gggtcagctg
    21001 attgaacacc gttgaaggaa gaggtcgtga gcctgccgtt catctccgag tcacaaggaa
    21061 caatttcaaa aaaaagcttc tcatgtttgt tgaatattgt tccttgtgac cgaggagttg
    21121 gcaggagaac accgtttatc cataaaaagg aatgtgacct aacttttgtc acattccttt
    21181 tttttatctt taataaacac gaacaataaa atgtttttct ttgttaacat tcgaaatttc
    21241 tttgacatca aaaaaagtga ttgttaaaat atgaatgtag aaaaactggg aggaaaaaca
    21301 atgacagcaa aaatctctgt gattatgggg agtacttcag attgggaaac aatgaaagaa
    21361 gcatgtcaaa tattggatga attcggtgtg tcttatgaaa aaaaggtcgt ttctgctcat
    21421 cgaaccccag atttgatgtt tgaatatgca caaaacgctc gaaaaaaagg aatcaaaatc
    21481 attattgcag gagcaggggg agccgcgcat ctgccgggta tggtcgcatc aaaaacaact
    21541 ttgccggtta tcggtgtacc ggtccaatca cgaacattaa atggtttgga ttcgcttctt
    21601 tcgattgtcc aaatgcctgg aggagtacct gtagctacta cagcaatcgg aaaagcggga
    21661 gcaattaatg ctggactact tgcgatacag atgctttcca tgtatgattt agaattggag
    21721 gctaaattgg ctgaaagacg ttcaatgttg gctaaaactg ttatagaaag tagtgatcaa
    21781 cttggttaaa cctttgttgc ctggttcaac gatcgggatc gtcggtggcg gtcaattagg
    21841 tcgtatgatg gcgattagtg caaaagaaat gggctttaaa gtaggtgtgc tggatcctgt
    21901 gagcgattgt ccagccgcac aagttgcaga ttggcacatt gaaagtgtct atgatgacac
    21961 ctttgcgctg aaagagcttg ccagaagaac agatgtcatt acctatgaat tcgaaaacgt
    22021 cagtgtagag gcgttaaatg cgattttacc catgtcattt attcctcaag ggacagactt
    22081 gcttgcgatt acgcaagacc gcctgttaga aaaatctttt ttggaaacga ataacatcgt
    22141 gattgctcct tatgcaacga tcgtcagtcc gacggatatc caagatgcga ttgacgggat
    22201 cggctatcct tgtgttttga aaaccactcg aggcggctat gatggcaagg ggcagtatgt
    22261 tttgaaaagt cgggcggatc tagctcctgc catggacctt ttaagagaag gaacctgtgt
    22321 tttagaagca tggatcccgt ttgaaaaaga gatttcgatc atggtggcag gaaatggtca
    22381 aggagatttc acgacttttc cggtcgtgga aaacatccac cacaacaata ttcttcatga
    22441 aacgattgct ccagccgcga ttgatcagga tgtgatcgag gaggctgagc gtattgcccg
    22501 tgtgattgca gaagcagtga gcctttcagg tgttttaggg gtagaaatgt ttttaacaaa
    22561 aacaggcggg ctatatgtga atgaattagc tcctcgtcct cacaattctg gacattattc
    22621 tattgaagct tgttctatga gtcagttcga tgcccatatt cgaggtattt gtggttggcc
    22681 attaggagaa aaagtacgtt tgataagcaa tgcagtaatg gtcaatgttt tgggagaaca
    22741 actgctggaa agctatcgct tgattgagaa taagccagac tggcaattcc atttctatgg
    22801 aaaaaaacaa gcaaaaaaag gtcgcaagat gggacatatc actatcttga cagaagacat
    22861 ccagcaaacg ctggaagaaa tcaaacaaac gaatatttgg gattagagga gaaaaaacat
    22921 gttagaacgt tatacacgcc ctgaaatggg gaatatctgg acggaagaga acaaataccg
    22981 tgcgtggctc gaagtcgaga ttttagcaga tgaagcttgg gcagaacttg gtgaaatccc
    23041 gcaagaagat gtgaaaaaaa ttcgtgagca tgcatcattt gatatcgatc ggatcttgga
    23101 aatcgaaaaa ttaacacgcc atgatgtcgt tgcgtttaca cgagcggttt ctgaaacatt
    23161 gggagaagaa agaaaatggg tccattatgg tctaacaagt acggatgtcg tagatactgc
    23221 ttatggctat ctcatcaagc aagcaaatga tattttacgg gaagacttga aacgttttac
    23281 ggaaatcatt ggcgaaaaag caaaagaaca caaatataca gtgatgatgg gtcggacaca
    23341 cggtgtccat gctgaaccaa ctacttttgg attgaaactt gccacatggt attcagaaat
    23401 gaaacggaac atcgaacgat ttgaacatgc ggcaaaagga gtagaagcag gaaaaatctc
    23461 aggagcagtg ggaacgttcg caaatatccc gccatttatt gaagagtatg tatgtaaaca
    23521 attggggatc cgtccacaag aaatctctac tcaagttctc cctcgggatc tacatgctga
    23581 atatttctca gcgatggcgc ttattgctac aagtattgaa cgttttgcaa cagagatacg
    23641 cggattgcaa aaatccgaaa cacgtgaagt agaagaattt tttgcgaaag gtcaaaaagg
    23701 ttcttctgct atgccgcaca aaaggaatcc gatcggttca gaaaatatgg ctggtctagc
    23761 cagagtggtg cgcggacaca tggtcactgc ctatgaaaat gtcacattat ggcatgaaag
    23821 agatatttct cattcttcag cagaacgaat catcttgcct gataccacga ttttattgaa
    23881 ttacatgtta aatcgttttg gcaatatcgt taaaaatcta acggtctttc ctgaaaacat
    23941 gaagcggaat atgtctgcaa catttggttt gatttatagc cagcgcgtta tgctgaaatt
    24001 gatcgataag ggaatgacaa gagaagaagc ttatgatctt gttcagccaa aaactgcgta
    24061 cgcttgggac aaccaagtgc agttccgccc gctgttagaa gaagatccaa ccatcacatc
    24121 ggtattatct aaagaagaaa tagacgatgc ctttgattat catcatcatt tgaaaaacgt
    24181 tgacgtgata ttcaaacgag taggtttgga ataaagaaga gtgagttgca aaattcaatt
    24241 aaaatagaat agcaaaaata atcgagtaga ggggaaagcc aactgacctt ccgcccctct
    24301 cacaccaccg tacgtacgga cccgtatacg gcggttcaat aagttgagtg tacgaactgg
    24361 tacttcaagg agatgtcctc atatccttgg cgggccagtt ctttgtctgt taatgatcga
    24421 tgaagaatat gacttttgga gactgaccaa ataccttttc ttgtatttga ccattcatac
    24481 gctttcgctt tatcgatccc taaacgaatc agattttttc ttttggttct tggattcttc
    24541 cattgtttcc aaatatattg tctgattctt cgcttcaacc aaccgtttaa ctccctcatg
    24601 aattctttca tctcaccaat tccatagtag ttgatccaac cagtcattag ttgcttgatt
    24661 tcttttaaaa taagttggat acttcttcca cggtttcttt tagtgagttg tttgagcttg
    24721 cttttcacac gctgttttgc ttttgcgtga gggcgaattt taataccttt ctttgttggc
    24781 agaatgcaga atccaagaaa ctttcgtttc aatggacttc ctaccgcact cttttctcga
    24841 tttaccgtca actttagttg ttcttcgaga aattgaatgg atttcttcat cacacgctgt
    24901 cctgctcgtt tgcttctaac atagatattg cagtcatcgg cgtatcgaac aaatttatgt
    24961 cctagatttt ctagcacttg atcaaattcg ttcaggtaga tgttacttaa caggggagag
    25021 agattgcctc cttggggcgt tccttcttca gttgttgtga tgagtccatt ttccattaca
    25081 ccactcatta agtattgacg gatcagtttt aggacttgtt tgtcctttac tttccgctca
    25141 atgaaataca tcagcttatc gtgatttacg gtgtcaaagt aggctttcat atcaatgtcc
    25201 accacatatc ggtaaccttg ttcataataa gattttgctt tcttcactgc gtcatgtgcg
    25261 ctgcgatttg ggcgaaaccc ataactatta tctgagaatt ctggttcaaa tagcggttgt
    25321 aacacttgat tgattgcctg ttgaagcata cgatcaataa ccgtgggaat tcctagtttt
    25381 cttacaccgc cgtttggttt cggtatttct actcgcaaaa caggctgagg tttatagttc
    25441 ccttggcgta aattggatag taattcctcg cggtgctctt tcaagtaagg aagcagttga
    25501 tcgacggtca tcccatctgc accagccgcc cctttatttc tgactacttg aagatacgct
    25561 tgattgagat tattccgatc tagaattctc ccaaacagat tttctacacc atcttgtttc
    25621 ctctgttcac cgcaagaagt gctgcgcact tcatcatacc cttcgtgttc cacactagct
    25681 ctttgatgat agccaagttt tcttgttttc tgcggtcgtc gcatcttctc acacctccta
    25741 aattattcaa gattcttatt gttcagtcct tcgtaacggt cagtgtcgtt actactatga
    25801 cctcggctga cttctcatga ttcaccatca tgtcgccatg atcgttgtgc tggtttgttt
    25861 tcattcaacg cccacaacac cctcatgaga tctcccccgg taagagtgaa aactttcctc
    25921 ccatgtaact gctagattta ctgtataggt ttcgggcagt attggacttt gtcttgtgat
    25981 gaagacttat ccgacctaat tcagccttgt atctagtttc tgttcgtcag ttcaggagtt
    26041 tgcgtccgac ttccttcagc cacaacctca cgattgccgc cttgtctttc gctaacagtt
    26101 cctactgcca agcctgtagt ggactttcac caccaagttt tcacccatgc agggcgcaca
    26161 ccaaaaaaga agcagatccg ttagcggttc tgcttctttt agtttattat attttcttat
    26221 caataatagg aacctgattt taaaagcggc tacctcttta ccgtgcctct ttacatacaa
    26281 aaaatagagg aattaagcgt aaatggcttg gctattataa ctaaaatgct ggttatggag
    26341 atgttgcagc aagttttcga gaaaagcgta ttccatctct tgtccattga ataagatctg
    26401 gatacgataa tgatttttga aacgcttctg ttcatgaatc tgactgattg aaagttcgcc
    26461 tttgtgttct gtctgataaa gaaaagtcct tttacggcat tcagcacagc gcttggttgc
    26521 tcggcggatt tttcggaatg tataaaaact agtatcttta ttgcataaat aaacgtcttt
    26581 gatcgacagc aaatcattat atagacagga acgttcttca gctgttaatt ctgataaaaa
    26641 aagctgacct tgttttattg catcttccat cggcaagtgc ctcctcgaac ccattatcca
    26701 aatttttagt taattctaat ataccatcat taagtataaa tgtaaacgct tgttgatggt
    26761 ataagatttt cgtttctgat aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac
    26821 atatttttgt tgatttataa aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa
    26881 aaacgatgta tttgctttta atgtaaataa aaaggagaga cgtacatgga gaagaaagaa
    26941 cttttgtatg aaggaaaagc caaaaaaata tatcttactt ctgatgagaa cttgatttgg
    27001 atagaatatt tagatcaagc aactgcgttg aatggcgcga ggaaagacca gataagtgga
    27061 aaaggagaat tgaataatca aatcacaagt gcaattttcc gttatctgac tcaaagagga
    27121 ataaaaaatc attttattga acaattgtct aaaaccgaac aattagcaaa aaaagtacaa
    27181 attatccctc tggaagtggt tatccgaaat attgcagcag gaagtttctc aaaacgtcta
    27241 ggtgttcccg aaggtaaaga attcatcaaa ccaatcattg aattctacta taaggatgac
    27301 cagttggatg atccatttat caatgaagag catatctatt tcttacaact tgcaaagccg
    27361 gaagaaatca gtgagctgaa agcccaagcg ttggctatta atgaaatttt gaccgaatta
    27421 tttgctaagg tcggtttggt tttagtagat ttcaagctag aatttggccg gtcgaatgga
    27481 caaattttgc ttgcggatga agtaacaccg gatacttgcc gattatggga tgaacgtacg
    27541 aatgaacata tggacaaaga cgtttaccgc agagatctag gtgatttgat cccagtctat
    27601 caagaagtat ataaccgtct atcggaacta actgaagaaa aggagcgagt atgatgtatt
    27661 tcgtaaaagt atatgtaacc tataaagatt cagtgttaga tcctcaaggg gaggcagtaa
    27721 aaaaagcagt ccatcgtatg ggatatgaaa caatcgaaga tatccgaata ggaaaatact
    27781 ttgagataca acttgctgat gcagaagaac caatcgatac agtgattgaa acgatttgtg
    27841 acaagctgct tgcaaatgta aatatggaaa cataccgata tgaaatcaaa aaaatggagg
    27901 aagtataaca tgaaatttgc ggtcatcgtt tttccaggtt caaattgtga cgcagatatg
    27961 ttatgggcag ttcgcgagat catgggcgct gatgccgaat ttgtacggca tgatgagtcc
    28021 tctttagaag gatttgatgg ggttttactg ccgggaggat tctcctatgg tgactatttg
    28081 agatgcggtg cgattgctcg gttttctaca atcatggaag aagtgattcg ttttgctgaa
    28141 gaagggaaac cagtattcgg tacatgcaat ggattccaga tattgacaga agcaggactt
    28201 ttgccaggtg tactgagacg aaatgagtct ttgcatttta tttgcaaaac tgtaccattg
    28261 aaagtcaacc ccaagacggc ctttacttca gagtatgaag ccgacgaaat aatctatctt
    28321 ccagttgctc atggggaagg aaattatttc tgtgacgaag aaacacttca agaactaaaa
    28381 aaaaataatc agattgcctt tacttataat gacaacatca acggcagcgt ggaaaacatt
    28441 gcagggatta cgaacaaagc agggaatgtg ttaggaatga tgcctcatcc agaacgtgca
    28501 gtagaagact tgctaggatc agaagatggg aaacggttct ttgcttccat tttaaaaaac
    28561 ttcggaaagg tgaccgtata gatgaaaaca ttgaaagaac cgacagctga agagatcaag
    28621 aaaaaaagaa tctatgccga atggggattg actgatgaag aatatcgaat gatcgaagaa
    28681 gatatcttag gaagaatgcc taattatacg gaaactggac tgttttctgt tatgtggagc
    28741 gaacattgtt cctataaaaa ttctaaaccg gttctacgca aatttcctac tagtggacct
    28801 catgtgttgc aaggccctgg agaaggcgca ggcatcgtcg acatcggtga tggactagca
    28861 gttgtcttca aagcagaaag tcacaatcat ccttcagccg tggagcctta tgaaggagct
    28921 gcgacaggag ttggcggaat catcagagat attttcagca tgggggctcg tccaattgcg
    28981 ttgctagatt cattgaggtt cggcgaatta gataatccaa gaacgaaata tttactagaa
    29041 gaagtagttg caggtatcgg cggatacggc aattgtatcg gcataccgac tgtaggcggc
    29101 gaaattgcat ttgatccttg ttatgaagga aacccattag tcaatgcaat gtgcgtaggt
    29161 ttgattgaac acaaacatat ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg
    29221 tatgtaggtg caaaaacagg tcgcgacggt atccacggag caacttttgc ctcagaagaa
    29281 tttaatcaag aagaagaaca gcaacgttct gctgtacaag taggcgatcc ttttatggaa
    29341 aagctgctgc ttgaagcgtg tttggaatta atcttgcatc attcggattc tctaataggt
    29401 atacaggata tgggagcagc aggacttgtt tcatctagtg cggaaatggc ttcaaaagct
    29461 ggctcaggac ttatattgac attagatgaa gtcccacaaa gagaaactgg gatgacacct
    29521 tatgaaatga tgttatcgga atcacaagaa cggatgttga tttgtgttaa atcaggagag
    29581 gaagaaaaaa tccaagaact atttcagaag tatgatctag atgcagtcac tatcggtaaa
    29641 gtaacagacg acgggcaata tcggctatat catcaaggag aagaagtagc aaatctgcca
    29701 gtcgatgcat tagctgaaga tgcaccagtt tatcataaag aaatgaaaga accagctcga
    29761 atcgtagaat ttcagcagtt agctccttat cagccagtta tcgaagaacc tggacaagta
    29821 ttgcttgatc tgctgcagca accgacgatt gcttcaaaac gttcaatcta cgaaacttat
    29881 gattcacaag tacaaaccaa tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg
    29941 gttagaggga cgaataaagc gttagctatg accacagact gcaacgcgcg ctatctgtat
    30001 ttggatccaa aaatcggagg acaaatagca gtggcagaag ctgctagaaa tattattgct
    30061 agcggtggta agcccttggc gatcaccgac tgcctgaact atggttctcc tgataaacca
    30121 gaagtttttt gggaattatc gacttcagct gacggaattg ctgctgcgtg tgaaacgtta
    30181 ggaactcctg ttatttcagg aaatgtctct ttatataatg aaacggatgg tcaagcaatc
    30241 tatccaacac caatgattgg tatggtcgga ttgattgagg atcataaaca tatcactact
    30301 caggaattca aaaaatcagg ggatctaatc tatatattag gtaagacgtt tgcagatttt
    30361 gatggcagtg aattacaaaa gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt
    30421 gatctatcca ttgaaaagag aaaccaagag ttagtattga cagccatcca aaacggattg
    30481 attgaaagtg ctcatgactg ttcagaaggt ggcttggcaa ttgcactggc agaatcagct
    30541 ttcaaacatc agctagggat atctgtacag tttgaattgt cctctgctca attatttgca
    30601 gaaactcaat caagatttgt gttgacagtc gcaccggaaa ataagacacg attcgaagaa
    30661 atgatgggag atgctgctgt tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt
    30721 tcagcaactg acggtcagat caaaatagaa actgcagtag caagaaagtg ctgggaggat
    30781 gcaatcgtat gtcttatgaa gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt
    30841 ggggtcatcc agacgccgct agtgtggcat acttcgggct ccatagtctt cagcatcgag
    30901 gacaagaagg tgcaggtatc gtgtccaatg atcgaggaaa gcttaagggg catcgagatt
    30961 tggggctgct ttctgaggta ttcaaagatc aaagaaaatt gcagcagtta acaggagaag
    31021 ctgcaatcgg acatgtacgt tatgcaacag caggcaatgg aagtgtggac aatattcagc
    31081 cttttctatt caaatttcat gatcagtcga tcggcttagc gcataatggt aacttgatca
    31141 atgctcgttc ccttagaaaa gagttagagg aaaatggggc gatcttccat tctaactccg
    31201 atacggagat attgatgcat ttgatccgac gaagtgaaga aacagatttt ttaaataaat
    31261 taaaaagtgc tttgaatgaa gtcaaaggtg gctttgccta tttattaatg acagaaacgg
    31321 caatgattgc cgctttggac ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa
    31381 acggagcata cgtgattgcc tcggaaactt gtgcattaga agttattggg gcacgtttta
    31441 taagagatgt ccagcctggt gagatagtga tcatcaatga cgaaggaatc cagattgatt
    31501 gctttacgaa ggacacgcag ctttctattt gttcgatgga atatatctat tttgccagac
    31561 cagattcaaa catcgcaggg atcaatgtgc atactgcacg gaaaaatatg ggacggaatt
    31621 tagcgaaaga atcgccagta aaagcagata tggtcgttgg cgtacctaat tcttctttgt
    31681 cagccgcaag cggttatgcg gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa
    31741 atcaatacat tgcccgaaca tttatccagc caacgcctga gctaagagag caaggtgttc
    31801 gaatgaaatt atctgctgta cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg
    31861 attcaattgt tcggggtacg acaagcagac ggatcgtcca tcttttgaaa gaagcagggg
    31921 caaaagaagt ccatgtgagg attgcttctc ctcctttgaa atatccatgt ttttacggga
    31981 ttgatattca aacgcgtaaa gaactcattg cggcaaatca cacgattgat gaaatcaaag
    32041 aatgtatcgg tgcagattct ttaggttttt taagtgaaga gggtctgatc gaatcgatcg
    32101 gtctggaaaa agatgctccg tattcaggat tgtgtatggc ttatttcaac ggagattatc
    32161 cgacgccgtt atatgactat gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt
    32221 tcttttaaaa gcagaccaag aagggagtat atgaattcaa tggcaaatgc atacgcaaaa
    32281 gctggcgtag atgtcgaagc tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa
    32341 aaaacggaac gtttaggtat gatgggcgct ataggaggat tcggcggttg ttttgattta
    32401 tcggtctttc aattaaaaga gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa
    32461 ttagcagtgg caatcgaagc agacaaacac gatacaatcg ggatcgactg cgtagcgatg
    32521 tgtgtcaatg atatcttagc acaaggcgca gagccgttat atttcttaga ctacttagca
    32581 acggggaaaa atgatccgtt acgtttggaa aatgtagtaa aaggtgtagc agatggatgt
    32641 gttcaaggaa atatggcgct gattggcgga gaaacagctg aaatgcctgg tatgtactca
    32701 ggtaatgatt atgatctagc cggatttgct gtagggatag ctgaaaaatc tcaattattg
    32761 acaggagaaa cgatcaaccc aggagatgtg ttgcttggaa tagcatctag cgggattcat
    32821 tcaaatgggt actctcttgt tcgcaaaatt ttctttgagc agcagcagtt ttctttatca
    32881 tcaaaactgc cagaattgaa aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc
    32941 tatgtttctt ccttgcttcc gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc
    33001 actggtggag ggtttgtaga aaatatcccg cgaatgttac cagaatctat ggctgcacaa
    33061 atcaaacttg gctcatggcc gattcttcca atattcggct gtttacaaaa atatggtgaa
    33121 attcctgaga tggagatgta tgaaatcttc aatatgggca tcggtatggt cctggcagtc
    33181 caagaatcga aagtaaaaga aatagtacac gaaattgagc aagctggcga aaaagtttat
    33241 gaaatcggga aagtgatcgc caaagaaaaa catcgtgtgg tgtttatagg agaagaacga
    33301 tgagaatcgc tgtttttgct tctggaaacg gaagcaactt tcaagcgcta gccgattatc
    33361 tatcgaaaaa aggattggaa tcttcgattg actggttgtt ttgtgatcag cctgaagcat
    33421 atgttttgaa acgtgcaact gcgttgagtg taccggcaga ttgtttttca cctaaagaat
    33481 ttgattcaaa aaaagagtat gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg
    33541 atttgatcgt attagctgga tatatgcgaa tcattggacc ggtattgctg aaaaattatg
    33601 ataaaagaat catcaatatc catccgtctc ttttacctgc cttccctggt ttgcatggca
    33661 tacgtgatgc ctttgaagct ggagtaaaag aaacgggtgt cacaattcat tatatcgacc
    33721 aaggtgtaga tactggacca atcatccggc aggaaaaagt gagaattgaa caggaggaca
    33781 cgttcgattc tttagaagaa aaaatccata gagtagagca tcgaatctat ccagaagtga
    33841 ttagtgaaat tattgaaaat ggaggctatc tgaaatgaca agagcattga tcagtgtatc
    33901 agataaaact gggattgtag cattcgccca aggtttgatt gaacaaggag tagaaatcat
    33961 ttcaacagga ggaacaaagc atgcgttgga taaagctggg atcaaaacgc tttcgatcga
    34021 agaagtgaca gggtttcctg aaatgatgga tggccgtgtc aaaacacttc atcctaaaat
    34081 ccatggtggt cttttaggaa gacgcgatct ccctagccat atggaggcaa tggaaacgga
    34141 aaatatccaa ccaatcgact ttgtttgtgt caatttatat cctttcaaag aaacgattat
    34201 gaaaccagat gtcgaaatag cagaagctat tgaaaacatt gatatcggtg gtcctagtat
    34261 gctccgtagt gcagcaaaaa accatgaatt tgtcacctct gttgttgatc catctgacta
    34321 tgaagaagta ctttcagaat tacgtcagta tgggcatact tcactttctt tcagacaaaa
    34381 actagcggca aaagtctttc gtcatactgc ggcatatgat gcactgatcg ctcaatactt
    34441 aacggattgg gtggaagaaa aagaaccgga aaaattgaca cttacgtatg aacgaaaaca
    34501 aacgcttcgt tacggtgaaa atagccatca agccgctgcc ttttatcagt ccgctcttct
    34561 ggaaaaatat tcgatcgcag cagcaaaaca actccatggg aaagaacttt cttataataa
    34621 tatccgagat gcagatgctg cgctacggat catgaaggaa tatgacgagc caacggtagt
    34681 cgccttgaaa cacatgaatc cttgtggtat tgggacagca tctacgattt tagaagcgtg
    34741 ggaagcagcg tatgaagcag atcctgtttc aatctttggt gggatcatcg ttttgaatcg
    34801 agaagtagat ctgccaacag cagaacagat gcataagctg tttctagaaa tcatcattgc
    34861 cccttcttat acacaagaag ctttggaatt actgcaaaaa aagaaaaaca tccgattact
    34921 gacagtagac tttgcgcagg aagaaaatca aaatcgagaa gaaacggtct cagtcttagg
    34981 tggacttctt gtacaagatc aagatctggc aatagaaaat gaagaagagt ggaaagtcgt
    35041 gacaaaacgt aagccgactc cagcagaagc aaaagcatta gcgtttgctt ggagagctgt
    35101 caaacatgtg aaatctaatg cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg
    35161 agccgggcag atgaatcgag tcggttcagt aaaaattgcg attgaacaag cgcaagagaa
    35221 aatggaaggt gcagttttag ctagcgatgc ttattttcca atggatgatt cggttgaata
    35281 tgcagccaaa catggtataa aagcaatcat tcagccagga ggaagcatca aagaccaaga
    35341 ttctattgat atggcgaata aatacgatct agcaatggtc tttactgatg ttcggcattt
    35401 tagacattag agaggagtcg gataaatgaa cattttggtg atcggtgcag gtggtcgtga
    35461 acatgcaata agtaaaaaac ttttagccag tccgaaggtg gatacggtgt attgtgcgcc
    35521 aggaaatccg gggatgacaa aagatggtat caattgtgtc gctatcagtg agcgagatca
    35581 ttcagcgtta atccattttg ttaagaaaga ggctattgat tggagtatcg ttggtcctga
    35641 agttcctttg ttaaatggga tcgtcgatga ttttatggcg gaaggattga aaatcttcgg
    35701 tccgacaaaa gcagcagctc tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga
    35761 tacttatcaa atcccgacag ctaaatccag aagttttgaa tgttacgaaa aagcagcagc
    35821 gtatatcaaa gaaaatggtg cgccaatcgt agtgaaagcg gacggcttag cagctgggaa
    35881 aggtgtagtc gtggctacca cagtgaagga agcgctggat gcggcagaac aaatgttgaa
    35941 ccagcatcga tttggggata gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga
    36001 agaattctcc cttttggcgt ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca
    36061 agatcataag cgggcatttg ataacgataa agggccaaat acaggcggaa tgggtgctta
    36121 ttcaccagta ccgcaaattt caaaaaagat gattgaaaaa gctgtggaag aagttttaaa
    36181 accagcggct ttgggaatga aagaactagg acgctctttc acgggtgttt tatatgcggg
    36241 tttgattgct acgaaggaag gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc
    36301 tgaaacgcaa gtcgttcttt ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt
    36361 attagagaat cgtacagtag agttaaagtg gcagcaagaa ggatacaatg taggcgttgt
    36421 ggttgcagct gccggttacc ccgaagaata tgagacagga atggttctac cagattttct
    36481 ggaagaagag ctttctgttt actatgctgg agtttcctca aataacggca aactagttgg
    36541 agcaggagga cgtctttatt tagtagaagc atacggtgag acgatcaaag aagcacagaa
    36601 aaaaatttac accgcgttaa tggataaaac gacagatgga acattttatc gtacagatat
    36661 tggagaaaaa gctgccaata gcgaactgat cgtgaagtaa atcagctgct tccatttata
    36721 aaaaatacaa caaacataat cggaagcgcc gattttagtg aagccttttc ataaagagtg
    36781 tggtacactt ttgttgtgta tataaataag gaggagttca gatgaaaaaa attcaattag
    36841 gtacttctga tcagaaagca gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg
    36901 aagatccagt aaaagtgatt gagacagctt atgaaaacgg cattgatttt tttgaccatg
    36961 cagatattta tggaaacggt gaatgtgaag aaatctttgc agatgctcta gcaaaaacat
    37021 caatcaaacg agaagatctt tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt
    37081 ttgatttttc taaaaaacat atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa
    37141 tggattatgt ggatgcttta cttcttcatc gtccagatac attggtagaa ccagaggaag
    37201 tagctgaagc gtttgatgaa ttggaacggt caggaaaagt tcgttatttt ggcgtcagca
    37261 atcaaaaacc aatgcaaatc gaattgctga aaaaatatgt tcgtcaacca ttagtagcta
    37321 atcagctgca atttggcttg aaacatactg gaatgatcga tcaagggatt catgtcaata
    37381 tgacagatga agcaagtatc gatcatgacg gtagtgtact tgattattcc cgattgcatg
    37441 atatgacgat ccaagcatgg tcaccatacc agtatggatt ttttgaaggt gtatttatcg
    37501 ggaacgaaaa attccctgaa ttaaaccaaa cattagaaga actagcagct aaatatcaaa
    37561 cgacaccaac tggcttggct tctgcttgga ttttacgcca tccagccaat atgcaagtga
    37621 tcgccggtac gatgaacgta gggcgaatca aggaaatcgc tcaagcttca gaaattaata
    37681 tgtctcggga agattggtac gaattgtacc gtgctgctgg aaacatttta ccttaaagat
    37741 tgtcataagc aggtcaaaag ggctataaat taaaaagaca gaataacttg aaagctgttt
    37801 tcagcttcga gatattctgt ctttttttat tgcaaatgga aagagtatca ttgtacggat
    37861 ttcgtttatt agttattttt gtttttaagg aaaagctgtg tccgatattc ttttggagaa
    37921 atcccttgtt ttttcttaaa taaataactg aaatagttag ggtcattata accaatttca
    37981 aaagcaatat ctgaaatacg atagtctgat tgctgcaata atttttttgc taattcgatt
    38041 ctttgttctg tcagataatc gatgaatgtt tggttaaacg attgagaaaa aatcgtactg
    38101 aaatgagagg gacttaatgc aacttgttga gcgacccaag ttaaggacat atctggatcg
    38161 gtaaaatttt ctttgataaa atccaatgca tggttcaaaa ttggctgata tttgttcctt
    38221 gaaggctgtg agggcagagc agttaagaaa gaaatgaaca tataaactgt cgaacggtaa
    38281 agcgagtcgt cggcgctgat tgctaagcgt tgactggtgg atgtgcaatg aaccatttct
    38341 tgcgggattt tcttttcttt caggcagaca tgctggagta gcttagtcaa gacaaataaa
    38401 cgatataatc gtgttcgagt tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta
    38461 gatacttcgt ttttcgataa tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa
    38521 tcaactggaa gtttcgcttc ttgaatcaaa tcctcatagc tgataatttg ttctttaagg
    38581 gaactggcgg tttcaagtat catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt
    38641 ctttctgcga caggaccaat ggcgacagaa aaattatttt tttgtccctt ttctaattca
    38701 tggaccaacg tttgggctac ctgataactg gtctcgatca cattttcttc aagagaatca
    38761 actattaaaa atttgatgaa tcgagaggaa acagcagaga agatcacttg ttgattctcc
    38821 ctaaataaaa acttcaaata atcactgaga tgagcgtaat cttcaaagtc tgtactgact
    38881 tggtttgctg ctaataatac ggtcattttt ttccctgcta aagagcgatt gaaagattca
    38941 gcaagtttca atgtttcact gatcgtaagt gagcctttga acaaaccgtt caagaaatga
    39001 ttttttttca attcgaaaac aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct
    39061 aaagcagtta ctgctttttc tattgcttgt ttcaattcgc tacttttaat cggtttaagc
    39121 agataatcat ctgcctgtac ctggattgct cctttcatat aatcgaaatc gtcgaatcca
    39181 ctaataaata tgagacgagt ccaaggaagt agtttccttg cttcttttga aaaagtcaac
    39241 ccgtccatga aaggcatttg gatatcagtc agaatgatgt cgggctgtaa gtcgataatt
    39301 gaagacagtg ccatctcacc atctccagct tcgccgacat aagtgattgg ataataagaa
    39361 ccaaggacag ttatttgttc ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata
    39421 aaaactttat acatgtttgt ttcctccaat tgttttggga gatagaggga tcatcagtgt
    39481 gacagttgtt ccttctcggt atttgctgtc aatcgtgata ggtttttgat catttccgta
    39541 ataaagaagg agacgcttgt ttacgttgta aagtccgtag ccgatactga aatctgaatc
    39601 gatccctttg gctaactctt tacgtatttc tgccagtttt tctgcaggga tgccaatccc
    39661 gttgtctata actttgaatt ggatcatctc atcaattttg catgtggtaa tacgaataaa
    39721 tcctttgtga cggacgtact tcgttccatg gtatacagca ttttcaatca atggctgcaa
    39781 gatcattttt aaaatagaaa caggaaaaag tgtttctggt atatcgatct tatagtcaag
    39841 catatggccg tatcttattt ttaagatgac tagataatca ttgatatggc taatttcttt
    39901 ttcaagagga atccagtctt gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc
    39961 atgggtcata gtcagagctt cttcaaagca gtcttgttcg atcaaagaaa taatggcatc
    40021 caaactgtta taaataaaat ggggagtaat ctgagcttgc aatacacgaa cttcactttg
    40081 tgctaaatgg tattgtttca aagcgttctc ccgtaaagac tggtttagat cttccgccat
    40141 tttattcatg ctagcggtaa gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa
    40201 gccaaggttc cctgaagaaa gttgttctga catctcgatc agctgattga tcggttcttg
    40261 gacctttctc tctaaaaagc gacgattctt tttcgcatag aaaaaaatgg tactaagaac
    40321 tccaagttcc actattgtta atagaatgag cgagcggaca agtgtcgtat tttttttgct
    40381 tgctaagtcg atctccacac gaacaaaatc ttgtaagata tctgacagca gttgagtgac
    40441 agaatctacc tgattgatga tctcttcatt ggtatccata aaatcttttg ccaagatatt
    40501 attgatcagc tcgttttgat aatcttccag tgtatcgatc gtacgtagcg atacatctaa
    40561 cgtactaatt tctttaagtg tatttgtatt atttttgatc tctcgaatat cattcctaag
    40621 ttcttctagg atattttcct cattgaactc atctacggtt acttggccag aaatcaagtc
    40681 ccacatactt tccaaaactt tttgatcaac cttcaaagca attgcatctg ctttttggat
    40741 atttgcgatc gtctgttgat aaatcaaaag ctgttgcgaa tataacagta tgctcagtag
    40801 caaagggata acagcaaata gaagcatggc tttgtttgct tgggcaaaaa tctgttttat
    40861 gcttaaattt tttgtcatga tacttctcca gtcaataatt tctggttggg atgttagcta
    40921 tattctgctg ggaaaagaca gtctcggaaa taaaaatatc tttaggtaat gtttttcctg
    40981 tttgaatatt tccaaaataa cgagtaacgg tattggctac ataccagccg acatcaggtt
    41041 tacactcgac tacacaattg acgattcctg agcgtagctt ctcgatcata tcttcttgtc
    41101 catcaatagt tacaatgatc aaatcttctc caggtttgat tgatgtttct tttatcgcag
    41161 ctaaagcacc gtgagtcatt tcatcactat ggctgtataa tacatcgatt tcggataaat
    41221 catttgtttc taaatatcgt ttcatctggt cttttccttt catccgaata aaatcaccga
    41281 caattcggtg aacaatagtc atcggaggtt tatggtcgat ggttccatct ttttttaggg
    41341 ttggtttacg attgattgat tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt
    41401 tctctgaacc agcaagttct aggattctga tttcctgttt ctttgaattt gtgaagtgat
    41461 tgctgacaaa taaacccgcc cgatttcctt ctgctttgaa actggggcca atgtgggtga
    41521 cgaaaagctc gggatcattc gtttgaatat gtctgtcgac aagtatgaca gggatccctg
    41581 ctcgctttgc ttcttttaat acagagtccc acccggattc ttgcaaagga gtaaaaatga
    41641 tcatatccac tttataggca atgaacgtcc gtatatcttg gatttgccgt tcctgattca
    41701 tgtagccatt tcggtagaga acttggtaat cttctttttc aagcgcagtg ataattgatt
    41761 cagtatgctt tttccgccag ctactctccg ttcctgattg cgaaaaacca acgactagtg
    41821 ggtcaggtgc ttcctttgta ttaggtgtac accccatcat ttggtaagcg attacaacaa
    41881 gggctaaaaa aaataaaaca cgtttcactt taaatcactc catctggatt tgttagtact
    41941 atcttatcag ataaaaggga aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga
    42001 aacttaaaaa aatccaagac aaaaaaagta cacctaaaaa atttaaagta aatcccataa
    42061 aaaaatcaat gttaacgctt tctttattag ctatactcgg tgtatcaatt gaaatggggg
    42121 ataaaaaatg aaaaacaaat ttagaaagat tgttgggact atcgctattt tgaccgcaag
    42181 cattctatta agtgcgtgtg gcaattcagg atctgcagat gatagtacgg ggtatgtagg
    42241 aatcgctatg ccgaccaaat cagcagaaag atggatcgct gatgggaaca acatggtctc
    42301 ggaattagaa aaactgggtt ataaaacaga tcttcaatat ggagaagata aagtagaaaa
    42361 tcaagtagca caaatagaaa atatgattac aaaaggggta gatacacttg tgattgcttc
    42421 tatcgatggt tcggctttaa ctgatgtgtt agctaaagca aaagaagcag atatcaaggt
    42481 gatcgcctat gatcgtttac tgatgaattc agaaaatgtc gattattacg cgacttttga
    42541 taattttgga gtaggtgtat cgcaagcagc ttatattgaa gagcacttag gattgaaaga
    42601 aggaaaagga ccattcacga ttgaattatt tggtggctcg cctgacgaca acaacgcact
    42661 aatcaattac aacggagtga tgtctgtttt acaaccatat atggacaacg gtcagttggt
    42721 cgtgccatct ggacagacga gtttcagtca aatcgctacg cttcgctggg atggttctac
    42781 ggcgcaagca aggatggata atctgttaag cgcaaattat actgaccaaa cattggatgc
    42841 tgttttgtcg ccatatgatc caataagttt aggaatcatt tcgtcattaa aaggcgtggg
    42901 gtatgggagt gaaagtaaac ctttacctgt gattactgga caagatgcga cagttgctgg
    42961 cgttaaatcg atcattgccg gggaacaaac acaaacgatc tttaaagaca cacgtatctt
    43021 agcaaaaaat acgattgaaa tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa
    43081 tgatactgaa acttatgata atggggtgaa aactgtccct acgtatttag caaatacagt
    43141 atctgtcgat aaagataatt atcaagcaga gctgatcgac accgattatt ataaagaatc
    43201 cgatctgaaa aattaagagg aaccaaacaa ggaactaaag agatctaagt cagagagagg
    43261 ataagaatta tggcggattg tattttaaaa atggcagata tcaccaaaaa attttctgga
    43321 atccgagcgt tagattgcgt gaatctgatg attgaacgtg gggaaatcca tgcattgtgc
    43381 ggagaaaacg gagcgggaaa atcaacattg atgaatgtct tgagcggctt gtatccatat
    43441 ggctcctatg acggggaaat cttttatgat ggaaagctgt gtcaatttaa agatttgaaa
    43501 gatagtgaag aaaaaggcat cgtcatcatt catcaagaat tagcactaag tccttatctt
    43561 tcaataaaag agaatatttt tctcggaaat gaacaagcag aaagaggcgt gattgattgg
    43621 gaactgacag aaaagaaaac atatgaactg ctgaataaag tcggtttgtc tatcgacccg
    43681 aatcttctag tatcccagat tggcgtaggg caacagcaac tagttgaaat agctaaagca
    43741 ttatcaaaat ccgtccgtct gttgattttg gatgagccta ccgctgcatt gaatgaagaa
    43801 gaaagcgcga atttgctgag attgatccga gagttgaaag agcaaggtgt aacctccatc
    43861 attatttcac ataagctgaa tgaaatcgtg gatatcgcag atcgaatcac cattttacgg
    43921 gatggacaga cgattgagac actagaaaat gaaatgatca gcgaagagca tattattcgc
    43981 ggaatggtgg gcagagattt agttgatcgt tatcctgaaa gaaaaccgga tattggagaa
    44041 gtttatttta aagtagaaga ctggacggtc tatcaccctc ttgatcacga gcgaatcata
    44101 aacgaccaca tcaacttgca tttgaaaaaa ggagagattg taggaatagc tggactgatg
    44161 ggagcgggca gaactgaatt cgctatgagt ctatttggac attcttatgg aagcaagata
    44221 tccggacgta tattaaagga aggggcagag atatcagtta agaccgttcc ttcagccatt
    44281 gcaaacggac tcgcttatgt ctcggaggac cgaaaatctt taggactgaa tctgctgatg
    44341 gatattcggg aaaacgtgac gctgagcagt ttggataaaa taagtcaaaa aggagtatta
    44401 gataaagaaa aagaagtaac tgaggcagaa aatttccgga aaaagatgcg tataaaaaca
    44461 aactccatcc atcaaattgt cagtagtctt agtggtggga atcaacaaaa agtcgtttta
    44521 tccaagtggc tgatgacaca acccgatatt ctttttttgg atgagccaac ccgtgggata
    44581 gatgttgggg caaaatatga gatctacacg attatcgaag aaatggcagc aaatggcaaa
    44641 gctgtctgtc ttatctcttc tgaacttcct gaaatattag ggatgtgtga tcgaatctat
    44701 acgatgaacg aaggacgtat tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc
    44761 ttgatgaaat taatgacgaa agaagaggtg ggttaagttg gaacaggcaa aaaatcttac
    44821 ggataaaaaa gagaaaaaac taaatttgaa aagtagagca gctgatcttt ttggtcgcta
    44881 cagcatggtg atcattttag cgggactact tattgcgttt caattgatga cggatggtat
    44941 tttctggcgt ccattgaata taactaacct tgttctgcaa aatagccata tattagtact
    45001 agctgcaggg atgttattag ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt
    45061 gatggcgttt gttggtgcaa ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg
    45121 gatgacagtt atcgcatgtc ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg
    45181 ggtagcttat gcagggatac cggcgtttat cgtgacttta gcaggattgc tgatgtttcg
    45241 tggactgaca caagttgttc taggaggcca atctctagca ccttttccag ctgttttcca
    45301 aaaaatgtct acgggttatt taccagactt aagcgaagga agcagccttc acttcttgac
    45361 attgatttta ggaatgatca tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa
    45421 tcgtcggaaa aatcatttat ttgaagtgga atctccaaca gctttcttgg taaaggcggt
    45481 atttacagca gtcgttgtac taggaataac ttatatcttt gcctcttatc aagggtatcc
    45541 gattattttg atcattcttg gtttgatcgt tgcagcatat gggtttttga caaataaaac
    45601 agtagcaggt cgacagattt atgcgacggg cggaaatcga aaagcggctg aactatcagg
    45661 gatcaaaaca aagcgaatca cgttctgggt attcgtcaac atgggagtca tggcagcttt
    45721 agctggatta gttttagctg ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat
    45781 ggaactggat gcaatggcgg cagtatattt tggtggtgct tcgacttccg gcggcattgg
    45841 aacaatcatg ggtgcgattg tcggtggctt ggtcatgggt gtattgaaca atggcatgtc
    45901 gattttaggc gtcggggtag actggcagca ggcaatcaaa ggattgatct tgcttttagc
    45961 cgttgtgcta gacttgtata ataagaaaaa acgaacaacg taggagaacg ccggttattc
    46021 agaaaaaaga ctgtgacaag acatttgtca cagtcttttt ttcgctaaaa gcgaacattc
    46081 attgtttcgt ttgtatagac taaaaataat atatgttttt ttaccattcg tataaattct
    46141 ctttttgctc ttgatttttt tgcttaattg agttaaatta catagggcgc taaaaaaagc
    46201 cttgattaaa ttaataatgt tcgtgttttg ctggatgtga acatcaggag gataatgtaa
    46261 tgaaagtatt tgattacgaa gatattcaat taattcctaa taaatgtatc gtaaatagcc
    46321 gttctgaatg tgatacaacg gtcacattag gtaaacatac attcaaaatg ccagtagtgc
    46381 ctgccaacat gcagacgatt attgatgaaa caatcgcaga attcttagcg gaaaatggtt
    46441 atttctatat catgcatcgg tttgatgaag cagctcgaat tccgtttatc aaaaaaatga
    46501 aaaagcgtgg attgattacc tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta
    46561 tagagaagtt ggcagaagaa tcgctaaatc ctgattatat cactatcgac atcgcgcatg
    46621 gacatgctaa ctcagttatt gatatgattc agcatattaa aaaatatttg cctgaaactt
    46681 ttgtgattgc cggtaatgtt ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg
    46741 cagatgcaac aaaagtcggg attggtccag gaaaagtatg tattacaaaa atcaagacag
    46801 gctttgggac tggaggctgg caactggcag ctcttagatg gtgtgcgaaa gcagctcgca
    46861 agccgatcat cgctgacggt gggatcagaa cacatggcga tattgcaaaa tctgtccgtt
    46921 ttggtgcgac aatggtcatg attggttcat tgtttgccgg tcacgaggaa tctcctggcg
    46981 aaacaaaagt cgaaaatgga atcgtgtata aagaatactt tggttctgct tcagaattcc
    47041 aaaaaggcga aaaacgaaat gttgaaggaa agaaaatctg gatccaacac aaaggatctt
    47101 tgaaagatac actagtggaa atgcaacaag accttcaatc atctatttct tatgctggag
    47161 gaagagatct ggaagccatt cgaaaagttg actatgtcat cgtgaaaaat tcgattttta
    47221 atggagacac aatctaaaaa ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc
    47281 attaagtaat aagaacagcc aaacaaaaat agttctttat atgttttgtt tggctggaat
    47341 tattatcgca gatacaagct tttgaacatc attattcaga ataagggact gtgataagat
    47401 ttttgtcaca gtcccttatg ttttgcaaaa aaagtttttc ttttttctcg taaattcggt
    47461 aaaatcaaaa gaaaaaatag acaatagaaa agagaagctt atgtgggaaa aagtagagaa
    47521 aaaacaagga ccgatttatc gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg
    47581 aaggatcaat cctggaagtc aacttgaatc agaacgaaaa ctagggcaac tttttggtgt
    47641 gaatcgttcc accgttgtcc atgcattgga agagcttagg gagcttgggg tactaacgag
    47701 caaacgtggc agcggatggt ttgttaatca gactgaatgg gggaaattcg ctgttccaag
    47761 aatcgattgg cggcaaatga tctctcctcg ttatgagcag acggactggt atgagcaaaa
    47821 aataagagaa gcaaagcaga tccaaaaaac atcgtttctt gatttatacg ctagcgagat
    47881 gccagatgag cttttgccga attttgagtt tccttcttat tctcttgaag aaatcttagc
    47941 ggaagaaaaa gaaatggatc ttttaggcta tactccgtta cgtaacaaaa tcaaacggta
    48001 tttggaaagt aaatttgaat tggcattttc ccccaaccag cttcttgtga ctggtggcgg
    48061 tcagcaagca atctttttga ttttacaaac gattctttca gctggagagg ggatagctgt
    48121 agagtcacct tctttttttt accgattacc tcttttcaaa gcttcaggaa cgcgtttatt
    48181 tgggataccg atggatgaag aagggatcga cttagaaaaa ctgaaagaat cgatccataa
    48241 aaataaattg aaagcagtgc ttatcaaccc gaattttcaa aaccctacag gaaaagtgat
    48301 gagtcaaaaa cgacgagaaa agctagtaga attgtgtcga cagtatcggc ttccaattat
    48361 tgaagacgat gtatttacgg atctttcatt tctaaaccaa gaagaagtcc ttcctatacg
    48421 aacgattgat ccggataatg tgttatacgt cggttcgtta tctagggttt taggaaaaac
    48481 aacgaaaatc ggttgggtga taggacctga gacttttatc tcgcaactag ctcaagcgca
    48541 agaaatgatg gagttttcga tgaatatcct tacacaaatc acagtggcta atgtatttaa
    48601 tgaagcaatt gatttgaaaa tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact
    48661 gataagcgct tggggagatt cacaatcgtt tttcaagctt cattcaattt taggtggtta
    48721 ctatgcctgg attacttggg atgggaaaaa actagacccc gaactagcag aaaaagtagt
    48781 agatatgggt cttggaattg caccaagtct actttttggg caagatataa atggaatcag
    48841 aatcaattac agtaggctgg atgaaaacca aataccgttg ttttattcaa agatgaaaat
    48901 tctagaaaag tggttaacag aataatttca caaagtaaat agattaaaga atataacagc
    48961 ttggatttaa atttcaagct gtttcttttt tttcggaaaa agaatacgat ataaagaaac
    49021 taagaaaaaa ccattatttg tacgtccgtt cacgatgtgt aaataaaata aatgtttgca
    49081 acaaaactgt ataacaccaa cgtttttaaa tagaaacaga tggttgtaag tttgattaga
    49141 aaatagaaaa aatgcagatg aaatataaaa cgctttcctt attgtgattt tattcactaa
    49201 tgctgttaat atgcggattg gcataatttc ctttcatcgt gaaaatttgt gcttttagct
    49261 tgtatttctc ataaatccat gataatttat taatgaagac ggttaaatag tgatacagtt
    49321 ttattcactg tttcaatcgc agaatgaaga gattttctta tagatgagag aggaatgtgt
    49381 gacaaatggc aaacaaaaaa gcaccgatcg acttccaagc actgctagat gaagtcaatg
    49441 cagatttccc agtatatcaa gcacttgatc aagatggaaa cgtagttaac aaagatttag
    49501 tacctgattt atccgatgat gaactcgttg aattaatgac tcatatggta tggtctcgtg
    49561 tattagacca acgttcaaca gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa
    49621 ctgctggaca agaggcaagt cagctggcta gtgcttacgc atttgataaa gaagatgttc
    49681 ttcttccagg ttatcgggat gtacctcaac tagtaaaaca tggtttacct ttatctcaag
    49741 cttttttatg gtctcgagga catgctgcag gtaattctta tccggaagaa ttgaaagctc
    49801 taccaccaca aattatcatc ggtgcacaat atgtacaagc agccggtgtt gcattaggtt
    49861 tgaagaaacg aaacaagaaa aatgtcgtct tcacttatac tggtgatggc ggttcatcac
    49921 aaggtgattt ttacgaagca atcaatttcg ctggcgctta ccatgcaaat gccgtatttt
    49981 atatccaaaa caacgggtat gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa
    50041 cacttgcaca aaaagctgtc gcagctggga ttcctggtat tcaagtcgat ggaatggatc
    50101 cgcttgcagt atatactgta tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac
    50161 cagtcctaat cgaaacactg acttatcgtt atggaccaca tacactatct ggtgacgatc
    50221 caacccgcta ccgtacaaaa gacacagatg acgattggca gaaaaaagat ccattgatcc
    50281 gcttccgtaa atatttgacg gaaaaaggac tttggtctga agaaaaagaa gaacaagtca
    50341 tcgaagcaac taaagaagaa atcaaagcag ctattgctga agccgacaaa gtaccaaaac
    50401 aaaaggtttc agatttcttg aaaaacatgt tcgaagtatc tccacaatca atcaaagaac
    50461 aaattgcaat ttatgaagcg aaggagtcga aataatcatg gcacaaaaaa caatgatcca
    50521 agcaatcaca gatgccttag cacttgaact agaaaatgac gagaatgtcg ttgtttttgg
    50581 tgaagatgtt gggaaaaacg gaggagtttt ccgggcaact gaaggattgc aggaaaagtt
    50641 cggagaagac cgagtattcg atactccttt agctgaatct ggaatcgcag gattgagttt
    50701 cggtcttgcg ttagaaggat ttcgtccagt tcctgaaatc caattctttg gttttatttt
    50761 cgaagcaatg gacgaagtag tagctcaaat ggctcgtaca agatatcgaa tgagcggcac
    50821 tagaaatcta cccatcacaa ttcgttcgcc atttggtggc ggtgttcata caccagaatt
    50881 gcattcggat aatttagaag gtttgatcgc tcagtctcct ggtattcgag tagtgattcc
    50941 ttccaaccct tatgatgcaa aaggactatt gatttcttct attagaagta acgatccggt
    51001 tgttttccta gaacacatga aactatatcg ctcattccga gaagaagtgc cggatgaagc
    51061 ttacgaagtt cctttggata aagcagcagt tactcgtgag ggaacagatg tatctattat
    51121 cacatacgga gcaatggtgc gtgaagcaat caaagcagca gacaatcttg caaaagaaaa
    51181 tatatctgtt gaaatcattg atcttcgtac agttgcgcca ttagatgtag aaacgatcat
    51241 tcaatccgtg gaaaaaactg gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg
    51301 cgttgccgcg caagtagttt ctgagatctc agaacgcgct atcctttcat tagaagcccc
    51361 aatcggacga gtttctgcac ctgatacagt cttcccattt ggacaagcag aaaatgtctg
    51421 gttgccaaat gcaaaagata tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa
    51481 gaagggacga aacaaagtca tggcttatca atttaaattg ccggatatcg gtgaaggaat
    51541 cgcagaaggt gaaatcgtca aatggttcgt caaaccagga gatacgatca atgaagatga
    51601 tacattacta gaagttcaaa atgacaaatc agtagaagaa atcccgtcac ctgttacagg
    51661 aacggttaaa aatgtgattg ttccagaagg taccgtagca aatgttgggg atgtattagt
    51721 agaaatcgat gcaccaggac acgaagacaa tgaaggggac agtggtgtag ccgcagaatc
    51781 ccaaactcca gctaaaccgg ctgctgaacc cactgttgat acagaatcag ctggatcgtc
    51841 aagcgaagga gtcttccaat ttaagttacc ggatatcggt gaaggaatcg cagaaggtga
    51901 aatcgtcaaa tggttcgtca aaccaggaga tacgatcaat gaagatgata cattactaga
    51961 agttcaaaat gacaaatcag tagaagaaat tccgtcacct gtcacaggga cagttaaaaa
    52021 cgtgattgtt ccagaaggca ctgtagcaaa tgttggggat gtattagtag aaatcgatgc
    52081 tcctggacac aatagtgcac cgtcaactag tgcgccatca gctgaagcac caaaagaaaa
    52141 agtggaaaca tcaggttcag caagtgtcgt tgaagctgcc gatccaaata aacgtgtatt
    52201 ggctatgcca tctgttcgtc aatttgcccg tgaaaaagat gtagatatct cacaagtaac
    52261 tgcaactgga aaaggtggca gagtaacaaa agaggacatc gaaaacttct tggcaggtgg
    52321 tccaagcagt gcaccagcga aatcagaagc gccagaagcg gcagcaccga aagaagcagc
    52381 tcctgcagca gaaagcaaac cagctgcacc agcaaaacca ttcaagtcca acttaggaga
    52441 cttggaagaa cgtgtagcaa tgacgccaac acgtaaagct atcgctaaag caatggtcaa
    52501 cagtaagcat acagctccac acgtgacatt gcatgatgaa gtagaagtgt ctaaactatg
    52561 ggataatcgg aaacgattta aagaagttgc tgctgcaaat ggtacgaaac ttactttctt
    52621 gccatatgtc gtgaaagctt taacagcgac tgttaagaaa tacccagtat tgaatgcatc
    52681 tatcgacgat gcaaaccaag aaatcgttta taaacattac tacaatatcg gtattgcaac
    52741 tgatacggat cacggactat atgtaccaaa tgtgaaagat gcagaccgca aaggaatgtt
    52801 tgctattgca gacgaaatca atgagaaagc aaaattagct catgacggca aactatctgc
    52861 agaagatatg cgcaatggaa caattacgat cagcaatatc ggatctgtag gtggcggttg
    52921 gtttacacca gtcatcaact atccagaagt agctatttta ggtgtaggaa cgattgcaca
    52981 acaaccaatc gtaaatgctg aaggcgaaat cgttgtcggt cgtgtgatga aactgtcatt
    53041 aagtttcgat caccgtatcg tagatggagc aactgcgcaa caagcaatga ataatatcaa
    53101 acgtctttta gctgatccag agctattaat gatggaagga tgataaacaa atggtagttg
    53161 gagattttgc tgtagaatta gatacagttg taattggtgc gggacctggt ggctatgtag
    53221 ctgccatccg cgctgctgaa atgggacaaa aagtagcaat cattgaaaga gagtatattg
    53281 gcggtgtttg tttgaatgtc ggctgtattc cttcaaaagc actgatagct gcaggacacc
    53341 attatcaaga gtcactagat tctgaaatgt ttggagtaac tagtgaaaac gtcaaactag
    53401 attttgcaaa aacacaagaa tggaaagaaa acaaagttgt ccatacgttg acttctggtg
    53461 ttggtttcct attaaaaaaa cataaggttg aaacaatcga aggagaagcg ttcttcgtag
    53521 atgatcacac actacgcgtc attcatccag attcagctca aacttattcg ttcaataacg
    53581 caatcatcgc aacaggttcc cgtccaatcg agattccagg atttaaattc ggaggacgtg
    53641 tgttagattc tactggcgga ttagcattga aagaagtacc taagaaattt gtgatcatcg
    53701 gtggcggtgt gattggtgcc gaattgggcg gagcgtacgc aaacttagga gcagaagtaa
    53761 cgattcttga aggctcacca caaattttac caacttacga aaaagatcta gtaaaattag
    53821 tagaagatga tttcaagaaa aaaggcgtaa cagtcgtaac gaatgcaatg gcgaaagaag
    53881 cagtcgataa cggtgacagc gtgacagtga aatatgcagt ggacgggaaa gaagaatccg
    53941 ttactgctga ttatgtgatg gtcactgtag gtcgtcgtcc gaatacagat gatatgggct
    54001 tagaacaagc gggtgtcgaa gtaggagaac gaggattgat cacggtggat aaacaaggac
    54061 gtacgaacgt acctaacatc tatgccatcg gtgatatcgt tccaggggcg gcattagcac
    54121 acaaagccag ttatgaagca aaaatcgctg ctgaagcaat ctctggcaaa aaagtagctg
    54181 tagattataa agcaatgccg gcagtagcct tcactgatcc tgaattggct tctgtaggta
    54241 tgacgatcaa agaagcaaaa gatgctggta tcgaagcaaa agcatataaa ttcccatttt
    54301 cagggaacgg tcgggcatta tcgcttggta aaacagaagg attcatccgt ctagttacga
    54361 cgatcgaaga taacgtgctt attggcgcgc aaatcggtgg agtcggcgca agtgatatgg
    54421 tctctgaatt agctttagca atcgaatcag gaatgaatgc tgaagatatc gccttgacga
    54481 ttcatcctca tccatctctt ggcgaaatcg tcatggatgc ttcggaatta gcattaggtt
    54541 taccaatcca tatttgattt gaataataca ggcgaaacgc aactgaaaaa tcagttgcgt
    54601 tttgtttttt agaattatca ataatattat tatgtaaact taaaaatatg acaacttctt
    54661 ggtttattac cacttcctat gctacactga agaggaatat gaaataggag agttgaagat
    54721 gcaagaatat cagtatccac ttgatttaga ttggacaaca gacgaaatgg tcattgtaat
    54781 gaagatgtgg gaagatctgg aacgtgcgaa tgaaaaaggg ataaacaatg aagctttttt
    54841 gaagacttat cagcagttta aaactgttgt caaatccatt ggtgaggaaa aacgattggg
    54901 acgggaattt gaaaaagctt ccggttattc tttatatcgt acagtgcagc aagcaaaaaa
    54961 aaatccaaac aaaactttga gaatgaacgg gtgagataaa tggaacagat gattgatcat
    55021 atcaagtcct ggcttgaaga agctggtgag aaaatcaaat cttctcaaca aacattaaca
    55081 atctcgcaaa aatcaaatcg aacggatcta gtaacaaatg tcgatcgaaa catccagaat
    55141 tttctaatcg aaaaaatcca ttcctttgat ccagaggcga aaatattggc agaagaagaa
    55201 gggtgtaatc aattatcgga tctcgatgga agagtcttta tcatcgatcc tattgatggc
    55261 accttgaatt ttgtgattga aggggaaaat ttttgtatta tgctcgctgt ttatgaatcc
    55321 ggcgttggaa agcttggttt catttatgac gtgatgagaa atgaactttt ttggggtgga
    55381 aaaggaatag gcgtgtataa aaatgatgag ccattgccta gaccagcaaa taaatcctta
    55441 tcggaaggct tacttggtgt gaatagttat cttttcggtc ataataaata tggaatccga
    55501 gaaattgcgg aaagcagcat ggggacacgt atgtacggat gcgctggtct tgaactagtg
    55561 gcaatcttga aaggaaacca cattgcttat atttcaaacc ttagcccttg ggattatgca
    55621 gcgggaaatg tcttattgga agagtttggt atggtaacaa gcggtctttt tggtactcct
    55681 ttgacatttg aaaaaaggga atactattta gcagggactt cttgtgcata tgcagaaatc
    55741 gcagaccttt tgaaaaaaga aggctgaaaa aaaggtagaa atcattcaca aaaatgataa
    55801 aaacgagcaa aagattaatt ttctcgaaaa aatgaaaaca ttttactata tttcatgaaa
    55861 aaagtctgct ataattagca gtcgagtaaa atttgccctg tcataaagaa ccaataaaaa
    55921 aggagttagt tacattgaat tatagaaacg atatccgtaa cgtcgcaatt attgcccacg
    55981 ttgaccacgg aaaaacaaca ttagttgatg aactattaaa acaatcagat acattagacg
    56041 cacatacgca attgcaagaa cgtgcgatgg actcaaatgc gctagaaaaa gaacgtggta
    56101 tcacgatttt agccaaaaac acagctgtag actataaagg tattcgcgta aacatcatgg
    56161 atactccagg acacgcggac ttcggtggcg aagtagaacg gatcatgaaa atggttgacg
    56221 gcgttgtgtt ggtcgtagat gcgtatgaag gaacaatgcc tcaaacacgt tttgtattga
    56281 aaaaagcact ggaacaacat atcacaccaa tcgttgtcgt aaacaagatt gacaaacctt
    56341 ctgctcgtcc tgagcatgtc gtagatgaag ttcttgaact attcatcgaa ttaggagcag
    56401 atgatgatca gttagacttt cctgtgattt atgcatctgc actaaatggt acgtcaagct
    56461 tgtcagatga tccagcagat caagaaccaa ccatggcacc tatttttgat acaattattg
    56521 aaaaaatccc tgctcctgtc gataacagcg acgaaccatt acaattccaa gtttcattac
    56581 ttgactacaa cgattatgta ggtcgtatcg gaatcggacg tgtatttaga ggaacaatca
    56641 aagtaggaga ccaagtagca ttaattaaat tagacggaac agttaagaaa ttccgtgtaa
    56701 cgaaattatt tggtttcttt ggactaaaac gtctagagat tcaagaagca aaagctggag
    56761 acttgattgc tgtctcaggt atggaagata tctttgtcgg tgaaacagtt actcctgtgg
    56821 atcatcaaga tgcgttacct atccttcaca ttgacgaacc aacattgcaa atgactttct
    56881 tagttaataa ttcaccattt gccggtcgag aaggtaaatt cgtaaccgct cgtaagattg
    56941 aagaacgttt gatggcagaa cttcaaacag atgtatcctt acgagttgaa ccaacaaact
    57001 ctccagatgc atggacagtt tctggtcgtg gagaattgca tttgtctatc ttgattgaaa
    57061 acatgcgccg tgagggatac gaattgcaag tatctcgtcc agaagttatt gaaaaagaaa
    57121 tcgacggtgt aaaatgcgaa ccgtttgaac gcgtgcaaat cgatacacca gaagaatata
    57181 tgggtagtgt tatcgagtcc ttgagcttac gtaaaggtga aatgcaagat atggtccata
    57241 caggaaacgg acaaatccgt ttgacattct taacacctgc ccgcggtttg attggttatt
    57301 caactgaatt cctttcaatg acacgtggtt acggaatcat gaaccatact tttgaccaat
    57361 atctgccaat gcttcctggt caaattggcg gacgtcacca aggggcgctt gtttcgatcg
    57421 atacaggaaa agcaacgact tattctatca tgagtatcga agaacgcggt acagtcttcg
    57481 tagaaccagg tacagaagta tatgaaggaa tgattatcgg ggaaaacagc cgtgataatg
    57541 atttgactgt caacatcacg aaagcaaaac aaatgacaaa cgtacggtct gctactaaag
    57601 accaaacatc tgtcatcaaa aaaccaaaac aattgacgtt ggaagaatct ttggaattct
    57661 tgaatgatga tgaatattgc gaagtaacac cagaaagcat tcgcttgaga aaacaaattt
    57721 tagagaaaaa tgctcgtgaa aaagcatcta aaaagaaaaa ataatctgta aaaggatgaa
    57781 gagagaaacc agcttgttat aaaaaatagc tggtttcttt ttttgtccaa ctcttttctg
    57841 tggagaagtc atctttgtca atggacataa attcagaaaa tacgccgaaa gacgtttaaa
    57901 agacttttaa aaaacttatt tctagagagt ttttgtttca taataagata atgtttcacg
    57961 aaaggagatc aacttgtcct tcgaagaaaa tcgaagtaaa atggcaagag aaaggagcgg
    58021 gaagatgaac gacttattaa aacaatactt tggctatgat gagtttagac ctggtcaaaa
    58081 agaaattatc cagaaagtca ttgatcagga aaatgtatta ggaatcatgc ctaccggaag
    58141 tgggaaatca atctgttacc agcttccagc tttactatta gatgggctta ctgtggttgt
    58201 gtccccttta atctctttga tgaaggatca ggtggacgcg gcgaatcaat taggtatacc
    58261 cgccactttt atcaatagct cgttagatgg ttacgaaaca gctagacgct tccaagaaat
    58321 cgatagacag cagtaccgtt tactttatat cgctcctgaa cgttttatca tgccggattt
    58381 tatccaagca atgaagcgat ggaacgtccg tatgatcgct attgacgagg cacattgtat
    58441 ctctcagtgg gggcatgatt tccgcccaag ttatttacag atggcgaacc agctagatca
    58501 actgccaaat cgtcctgtaa ttgttgcttt gacagctaca gcgactgtgc aagtagctgc
    58561 tgacataaaa agacttttaa aaattccaga aaacaaccat attcagactg gttttgaacg
    58621 agaaaatcta cgatttcaag taattaaaga tcaaaaaaaa gaacaatatc taatcgaata
    58681 tttaaagatc aacaaaaatc aatctggtat catttatgca gcaacgagaa aagaagtaga
    58741 ccgtctctat catttgctta aaaaattcga tttttccgtg ggtagatatc atggtggtct
    58801 aaatgagaat gagcgaacag aaatgcaaga agccttttta tacgatcgct tgcagctgat
    58861 tgtagcgaca aatgcatttg gtatgggtat aaataaaagc aatgtccgtt ttgttatcca
    58921 ttatcaaatt cctggctctc tagaagcata ctatcaggaa gctggtcggg cgggaagaga
    58981 tggtctttcc agtgaagcca tcctgctttt ctctcctcaa gatatccaag tccaaaagtt
    59041 ttttatccag cagtcccaaa gagaagaagg gcaaaagcaa aaagaatatg aaaaattaaa
    59101 agcgatgaca gaatacgtgt atattgagtc ctgtcttcag caatacatcc taaactattt
    59161 tggcgagaca agcagtccgt gcaaccgttg tggtaactgt ttagatgaca gagaaatagt
    59221 agaagtaacg acagaagcac agatggttct ttcttgctta aaacgtatgg gtgagaacta
    59281 tggtaaacaa atgctgatga aagtcttagc aggatcgaaa gaacaaaagc tgcaagcttt
    59341 aggttttgga catttatcta cctatggact gatgaaaaac caatcgcaaa aagaaacgat
    59401 gcagttaatt gaatatttga tatcgaatgg ctatcttctg accatcaatg gtgagtatcc
    59461 tgttttgaaa gtaacagaaa gagggataca agtattgaaa ggacaagaat ctgtttatcg
    59521 aaaggaaccc aagaaagtcc agcagctatc ggatgaagaa accgatacac tatttgaagt
    59581 gctgcgggaa ctgcgaacgg atctagcatc agaagcaggc gttcccccgt atgtcgtatt
    59641 ttcagattcc acattgaaag aaatgagccg aatacgtcca tcaagcagat tggagatgct
    59701 tcagataaaa ggagttggcc aaagcaagct tgataaatat ggcgaagcct ttttatctcg
    59761 gataaaaaat gcggactcta acgttctgga taagtagaaa gaacgaatac gtaaaaatga
    59821 ataaaaacaa ctggttaaat ctgttttttt tgctccttat gaaaatcaaa tatgttataa
    59881 ttaaggaatt agaatgggag gtaagcacag atggattctt tgtcgaaaaa acttgcgatc
    59941 caagtattaa atgatgaagc agaacggatc aaacgattaa tccgaaatca aaacaacagt
    60001 ctctgtatct cacaatgcaa agccttcgaa gaagtggtag atacacagat gtacggcttt
    60061 tcccggcaag tcggttttgc tgtccgtata ggagtaatcg gaaagaacga gggccagctg
    60121 atgttaagtg agctagaacg agaattgaat cagttatata gtgaggttta ccaagaaatt
    60181 tatgataaaa aagaagttgg caaggaggaa tagacttgcc taagaaagtg aaaaaaaggc
    60241 atctattaga ctatagcatc ttgattccct atttaatttt atgtgtattg ggattgatca
    60301 tggtatatag ttctacgtcg tatctattat tagaaaacgg acaaaatccg tccgcatcag
    60361 tcattaacca gagtattttt tgggtgctta gcttgattgc tatcgcacta ctttataaaa
    60421 tgaaaacaga tgttttgaaa aaccagcgtt tgatcatggc agccatcgca gttttgacga
    60481 ttttgctgct gattgttgtg ttttttggta aggagatcaa tggggcgaaa ggttggctgc
    60541 aaattgcagg attctcgatc caacctgccg aatacctaaa aatcatttct atctggtacc
    60601 tgtctctgac tttatctaaa agacaaaaca gtgtacaaaa agattttctt gggactgtga
    60661 aacgtccact tgcaatggtt atcggactta ctgcattagt cgctattctt cccgattttg
    60721 gtaatgcggc agttatcttt ttgattattt tggttctgct tttagccagc ggagtcaatt
    60781 atgtgtatac tttgattgta ggagtaggag gcttttgtct aagtactttt acgatctggc
    60841 tgatcaatat cacaaacgga aagatcttac ccggacgttt acagtatatc tataatcgat
    60901 ttgctattta ccaaaatcct ttctcagacg aattaaataa agggcatcaa ctagtcaacg
    60961 gctactatgc catgttcaac ggaggactat ttggcagggg attaggtaac agtatccaga
    61021 aaaaaggatt tttacaagaa gcacaaaccg attttattta tgcaatcgta gtggaagaac
    61081 tgggagtgat tatggggatt ttgatattag cgttgctatt ctttatgatt gtgcgcattg
    61141 tccttgtagg tatccgttca aaagatccgt tcaattcgct tttgtgcatt gggatcggcg
    61201 caatgttttt gatccaagta tttgtcaatc ttggaggaat tactggcgtt attcctttga
    61261 cagggatcac gttcccattt ttaagtcaag gaggctccag tttgctgatg ctttcgattt
    61321 gtgtcggctt tgtcctcaac atcagtgcgg atgaaaaacg caagagctta ggtttataat
    61381 aaaaaaagat gtaggagtgg ttcgatgaaa aaagttttag ttgctaacag gggtgaaatc
    61441 gctgtacgtg tatttcgtgc ttgtacagaa ttaggaatta aaactgttgg aatctatgca
    61501 gaagaagatg aatattccgt acaccgtttc aaagcggatg aagcatattt agtaggacaa
    61561 ggaaaaaaac cgattgatgc gtatctagat attgaaggga tcatttctat cgcgaaagaa
    61621 tgcggagctg acgctattca tccgggttac ggtcttttgt cggaaaactt gaattttgcg
    61681 caacggtgcg aagaagaagg catcattttt gttggaccca aactgcatca tttagatatt
    61741 tttggagata aaatcaaagc aaaagctgca gctatcgaag cggggattgc ttcgattcca
    61801 ggcacagatg gaccaatcgc ttctatagac gatgccttgg agtttgcgaa acaatacggt
    61861 tatccgatta tgatcaaggc agctctaggc ggcggcggac gcggcatgcg tgtagctcac
    61921 gatgaaaaga gtgcaagaga gggctacgaa cgtgcgaaaa gcgaagcaaa agcagccttt
    61981 ggtagtgatg aagtgtatgt tgaaaaatac atcgctaatc ctaagcatat cgaagtacag
    62041 attctcgggg atacgcatgg aaacgtcatc catctttttg aaagagattg ttctgttcag
    62101 cgccgtcacc aaaaagtagt agaagtagcg ccttgtgtct ctatgaatga acagcaacgt
    62161 caaaaaatct gccaggcagc tgtccaattg atgaaatatg tcgggtatgt caacgcaggt
    62221 acagtagaat ttcttgttga aggagatgat ttttacttta tcgaagtcaa ccctcgcgtc
    62281 caagtggaac atacgatcac agaaatgatt acagatattg atatcgtaac aacgcaactg
    62341 ttgattgctc aaggtttgga tctgcataaa gaaatcggat tgcctcagca agaaggaatt
    62401 aaattaaatg gttcagccat tcaatgccga atcactacag aagacccgtt gaataacttt
    62461 ttaccagaca cagggaaaat cgatacgtat cgttcacctg gtggttttgg cgtacgtctg
    62521 gatgtcggaa atgcttacgc gggctatgta gtgacaccgt attttgattc attgctagta
    62581 aaagtatgta cgcatggtgc tacctttgaa acagccattc agaaaatgga acgttgcttg
    62641 aaagaattta gaatccgtgg agtgaaaaca aacattccat ttatgctcaa tgtcatcaca
    62701 catcctgaat tccaatcagg aaatgcaaaa acaaccttca ttgatagtac agcaacatta
    62761 tttgaatttc ctcgactacg agaccgcgga aacaaaacga tgaaatatat cggtgaaatt
    62821 actgtgaatg gttttccagg tatcgaaagt ggcgaaaaac cattttatga agaaccacgt
    62881 atgcctaaag atctaatcac aagaactgat tacgtaacgg ctaagaatgt attagatgcg
    62941 aagggtgccg atgctttggt cgaatggatc aaaggacagg aaaatttgtt gttgacggat
    63001 acgacattta gagacgccca tcaaagtctg ctagcaactc gtgttcggac aaaggatttc
    63061 aagcagattg cacgtttgac tggagaaggt cttcctgaac tcttttcaag tgagatgtgg
    63121 gggggagcaa catttgatgt ggcttaccgc tttttgaatg aagatccttg gcaacggttg
    63181 agaaaaattc gttctttaat gcctaatacg ttgctgcaaa tgcttttcag aggttcaaat
    63241 gccgttgggt attctaatta tcctgacaat gtattggtgg aatttgtcaa agaagcagca
    63301 gcgcaaggaa tcgatgtatt tcgaatcttt gatagtttga actggactcc acaaatggaa
    63361 aaaagtatcc aagctgtacg ggatactggt aaaatcgcag aggcagctat ttgctatact
    63421 ggcgatatca acgatccaag tcgggcaaaa tacaatgttc agtattataa agacatggca
    63481 aaggaactag aacaactggg tgcgcatatc attgcaatca aagatatggc tgggctgctt
    63541 aaaccgcagg cagcttatcg tttgattagt gaattgaaag aaacgacaga tctgccaatc
    63601 catctgcata ctcatgatac cagcgggaat ggaatcatca cttattctgc tgcttcaaaa
    63661 gcaggagtag acatcgttga cgtggcaatg agtgcaatga gtgggaatac tagtcagcct
    63721 agcatgagca gcttgtatta tgcactggtc aatggtccac ggctgccaga aatcacgatt
    63781 gaaaatgcac agaaattaaa ccattattgg gaagatgtgc gcatgtatta caaaccgttt
    63841 gaaaacggct tgaatgctcc tgaaacagaa gtatatatgc atgaaatgcc aggaggacag
    63901 tattcgaatc tacagcaaca ggcaaaagct gtcggattag gtcatcgctg ggatgaaatc
    63961 aaacaaatgt atcatactgt caacttgatg tttggcgata tcgttaaagt aactccatca
    64021 tctaaagtag ttggagatat ggcactattt atggtccaaa atgatcttac agaagaagat
    64081 atttatgaaa aaggcgaaac actaagtttc cctgaatctg ttgtgacttt cttccaagga
    64141 gaactagggc aacccgttgg cggatttcct aaaaaattgc aaaagattat tcttaaaggc
    64201 agacctgcat tgaatgaacg tccaggtctt ttggctgaat cagtcgactt caacgaagta
    64261 aaaaaagaat tggcagaaaa aattggctat gaaccaaaac aagacgaagt attaagctat
    64321 ttgatgtatc cgcaagtctt tttggactat caaaaagcat ataatcaatt tggcgatgtt
    64381 acattactgg acacaccaac atttttccaa ggtatacgtt tgggtgaaac aatcaatgta
    64441 caaatcgaac gcggaaaaac gcttatcatt cgtttagatg aaatcggaga acccgatatc
    64501 gaagggaatc gcgtactgtt cttcaatttg aatggacaaa gacgtgaaat cactatcaaa
    64561 gataattcga tcatcagtac ggtccaaacc cgattgaaag ctgaaccgac aaaccgagaa
    64621 caaattggag caacgatgtc tggttctgtt ttggatgtat tagtgaaaaa aggcgataac
    64681 gttaaaaaag gtgatacgtt gatgattact gaagcgatga aaatggaaac ggccatcgaa
    64741 gcacgttttg acggagaagt cgcacatgta tatgtgtctt caggagacac tatttcgtct
    64801 ggtgaccttt tgattgaagt gactgagaaa taataagcga aaggtgggga aacatgaaaa
    64861 gactgggttt gttttggctg attctgctat tagttattgt ggcattctac atggaaccag
    64921 tcttgtttcc gccaaaactt gaagtgaagg aaaactctga tcaacaaata tcaaaccaaa
    64981 tgacaacgtg gaaataccag gagcttaaag caactggttt ttctacttat atcggaaaac
    65041 cgatcgatca gctggaaaag gattttggcc aagcctatga tcgattaact agcggatttg
    65101 gttttgaaac aagatattat gaaaataaag ctagtcatct cacatttgaa gcgaacatcc
    65161 aagacagcag agtcacaact gttaaagtac tgcaaacagg gcctgctgat atcgcgccgt
    65221 tttatttagg gatgacgatg caagatctta cgaaaatcac tactatctat actaatttca
    65281 cttttgagta ccatgataca gaagttggaa tcgaactaat ggaagaggat atgaattatc
    65341 gtccgctaat tgcttttgat aacgacactt ttgctatttt attttttgat caaacaacaa
    65401 acggcctatt ttcagttgtg tatttagata aagatagtct tttgaaacta ttgccatatc
    65461 aagtgtttgg tgaaggcctt ccacattatc aagcagataa atcggctgat tgggaatcaa
    65521 tcaatcgcgt taaagaacga aaaagtacga ctttattaaa tatgcttaga agagaagacg
    65581 aacttcccat atacaatcaa acacttgcct ttcaaaacca cagtcagctg ctactacatg
    65641 attttttgac aaggcctgag gaaatattgt cagaggaacg tatggctgat tggcaaaaat
    65701 cgctaggcag tgctcaaacg acagtgaaat tctcactgac gaatgatgaa ttggagaagt
    65761 taatcagtaa acaaaaatta gaaaatacta gtgggctatt tattcatccg gcgattgacg
    65821 ctactttttc gtttttatat tggtacagcg atccttacaa ccatgaccgt ttcatggacc
    65881 cgggaacgga ttctgtaggc attgcttttt ctaaagaaaa tatgttagtc ttattgcaag
    65941 aagaaaacgg agaaagtagt gatagcagtg atcgttaacg aagagctgtt tcaactggag
    66001 gatcaatgcc tccaagtcgc tgaaatgata aaaaagagta aaacgatggc ttcttatctt
    66061 gaacataaac agtcaatgga agaatctgca aaagtttgcc agttgaaaga agcgttcttg
    66121 tctaagaaag aagcatttga aaatgtagcg gcatatggtg agtatgcacc tgattatcgt
    66181 gaaaaaaaac gagctgttcg aaaagcaaaa agacagcttg atatggatga gcatgttgca
    66241 gctttccgat atagtgaaac acagctgcaa agtctgttgg atcaaattgt ccaagtactt
    66301 gccgaagaag tttctaatga aatcaaagta gatgcaggta gcccgttttt tgaaacgaaa
    66361 aaacactttg gatgcggagg taattgtcat gcaattagac aatagtgaat ttgaaataac
    66421 aaaacgacgc gggctgatcg tatgggtcta cagcttaaaa caattaaaga atctgaaaaa
    66481 gttcggcttg ttgcattatg tctcaagaag aatgaaatat gtcgtgcttt acttaaatga
    66541 agagacattg gaagaaacag aagaacgaat ccgtaaatta cattttgttc gaaacgtaga
    66601 acgttcttac cgaccggata tcgaaatgaa ttttgccgaa aaaataggaa acaaaacagt
    66661 attaaaagac gaaggtttcg aaattgaaga gctaaataca gaaatccgat tagctgaaca
    66721 tctttaaaaa tctcttatga gcagttttta aataaaaaat aacttggata acgatcgatt
    66781 tttgatcatt gtccaagtat ttttttggta tactagtacc agtaccattt ctaaggagtg
    66841 agtagatgcg gataatatca ggaaattatg gcgggcgccg tttaaaaagt ttagcagggg
    66901 cgaacaccag accaactaca gataaagtaa aagaatccat attcaatatg attggaccat
    66961 attttgatgg agagacagta ttggatctgt ttgcaggaag cggtggttta gctatcgaag
    67021 cagtatctag aggctgcagt catgcggtat gcgtagacaa aaattaccaa gcgctaaaaa
    67081 tcatcaaaga aaacatcgaa attacgaaag aaccagagaa atttaccaca ataaaacttg
    67141 atgcggacaa agcaatcgaa cggctagcag cggagaaaca acaattcgac tacttgtttc
    67201 ttgatccgcc atatgcaaaa caaaaaataa tcgatcaaat ccataaaatg gaagaactgg
    67261 gacttttttc taaaaccgca gttatcgtat gcgaaacgga taaaacagtc gaattgccag
    67321 aaactgtggc tggattccat caaataagaa aacagattta tggcataacg gccgtaacta
    67381 tctatagaaa agagggaaat caatgaaacg tgcattattc ccaggaagtt ttgatccttt
    67441 tacaaaaggt cacttagata cggtggaacg tgcggctaaa ttattcgatg aggtagtaat
    67501 tggtgttttt atcaatactt caaagaaaag tttgtttccc ccagaagaaa gaatgacatt
    67561 gatcacaaaa gctgtttctc atcttcctaa tgtaaaagtc atgcatcaag aaaatcaatt
    67621 gacggtagaa acagcaaaag agattggtgc agatgcgttg atcagaggca tacgaagtat
    67681 caaagacttt gaatatgaac gagagattgc tcagatgaat catcatctat atgatgaatt
    67741 ggaaactgtc ttcttattag caaaaccaga atatagtcac gtgagttcca gtattttaaa
    67801 agaagtactg cactttggcg gagatgtgag cagctactta ccgccagtga tcaacgaagc
    67861 tttagctgga aagcgtgaat caaatgaaag ctaaacaatg gttgaaaaca gtactgatta
    67921 tcatatttgg aatgttgatc attggatttg tagtagttcc cttgccgtat tatgtagaat
    67981 caccgggagc cacgatcgat ctgaaagaac taattacggt caatgataag gaagataaag
    68041 gttctgggtc tttctctctt acctctgttg gtatcaggca agctacaggt ttcttagctt
    68101 taaaagctaa aatgacccct tttgaagaat tgatcagtga agaagaattg actggtgggg
    68161 cgacaaatga agaatataat caaatgcaac agtattatat ggattcttcc caaaatgcag
    68221 caatcgaaca agcgttaaaa cttgcagaca agccttataa aatggaattc aaaggcgtat
    68281 atgtcatgag tgtagagaaa acatcgaatt tctttggcaa gctttcagtt ggagatacag
    68341 taacaaaagt agacgggaaa agctttcaaa gtacagaagc atttatggat tatgtaaaaa
    68401 gccaaaaagt tggacaaaca atcgaaatca gttatttgca taatggtgaa gaaaaaacag
    68461 cttctggtga tctgatcgag ttaccaacag ataaaaaggc aggaataggt atcacgctta
    68521 ctgaccatac cgagatcgaa tcagatacag atgttcgtat taattctggc tctatcggtg
    68581 ggccatcagc gggattgatg ttcactttag aaatctatga acaagtcact ggtaaaaact
    68641 tgcgacatgg taagcaaatt gcaggaactg gaacgatcaa cagtgaagga gaagttggcc
    68701 gaatcggagg aatcgataaa aaagtggcaa gtgcggataa agctggcgta gagattttct
    68761 ttgcaccaga tgatacgatt tcagacgatg ttaagaaaga atatcctgaa ataaaaacca
    68821 actacgaaga agcaaaagct gccgctaaaa aattgaattc ctcaatgaaa atcgtaccag
    68881 taaaaacagt acaagaagcg cttgactatc tagagaaaat gaaatgaaac taaataatta
    68941 aataggggtt gtgacacgag ttctgtcaca acccctcttt ttcgtcaaaa atcttcacga
    69001 taaaaataaa aacaaaagaa aaaattgacg taattagatg ttgaagggac gattttgcca
    69061 gagctcactg tttcttcaat tttaaatgaa aggagtaatg aatgattttt actggtcatt
    69121 ctttgaaaaa agaacaatga tagaaaaaat cagcaagaaa atactagctt cacccaaatt
    69181 gatcatttgg atgtctatga tagttcttat cttttgtatc gcaagtggtt ttttattatc
    69241 aaatttgcta ttttatagag aaacagaaga gactgctgca aaagaaatac tttcttcgtt
    69301 tagttccagt ggagaagatc catcagctga aggaaacgat gtagaagagg atgctcgtcc
    69361 aaaggtcatg tacaccgata tcaaaggaag tgtgaaggag cctggtatct attccttttc
    69421 ttcagaagaa cgggtctatg atgtactaaa gcgtgcaggt ggattattag aagaagcgga
    69481 tagcgatcga atcaactttt ctgcgaagat agaagatcag caagtcctat atatccctgc
    69541 tgtaggtgaa gagctgccag aacatcttga tcagttggca tcctcggaag gaaaacagcc
    69601 tacagcagat tccgagcctc ccaaaataaa tatcaataca gccactccat cagaacttca
    69661 gcagattcct gggatcggat cagtcaaagc gcaagaaatc attcgattta gagaagaaaa
    69721 cggatccttc cagaaagtgg aagacctgca ggagatttct ggtatcggtg aaaagacagt
    69781 tgaaaaacta aaaaacttcg ttacaattaa atagaatgat tcaaaatcga ctggcacgag
    69841 caataaatgg acgctaatgg atactaagaa taatccaatt ctaagagctt ggcaggacga
    69901 ggaggtagta tttttggata ggaaatagct tgattgttcg caaagaaaca ttaaaaaaac
    69961 caatgctgaa tgtctatctc caaaataaaa tatctgggat tcatattatg aatacggctg
    70021 tcagcggcaa taacagtcaa gctctacgag aacgctttgc caaagatgta cttagctata
    70081 cagcagataa agtatttatt ctcattggga cgaatgatct agcagagcat aaacaacttt
    70141 ctaaagaaac gtaccaaaaa atctgcagtg gatgatagtt cagctgaaaa aagactatag
    70201 ttctgatcat gctttcttta tcacgccacc agcagtcgat gagacaaaac aaaaatatcg
    70261 gaataacaag ttgatcaaag aatatatctc tgttctcaca gaagtagcaa aacgccatga
    70321 ttgtgaagta tcgattttta tacggaattt cttgaacaaa tggattcgaa gaatttttat
    70381 aatgggctaa tggatgacgg acttcatttc ggcagtgaag ggtaggatct tttgtcagac
    70441 aggatgattc gttatattta aagaatattt tgtttaagca atgagtactt tttaatcaac
    70501 ttgaaaaaac ggaggaatat aaaacatgtt agaaaaatct tcaaaagcat gcgatacgaa
    70561 taaagaaaaa gttactgata agtcacataa tgaacgcatt ccttgggacc agtactttat
    70621 ggctcaggca gtactgttat ctttacgtag tacgtgtaca cgtttagaag taggagcgac
    70681 actcgttcga gaaaaaagga tcattgctgg cggctataat ggagcagtca gtggagatgt
    70741 ccactgcata gatgaagggt gttacgtcgt ggatggacac tgcttgcgaa cgatccatgc
    70801 agagatgaat gcactcctac agtgtgcaaa acttggtatc ccgacggaag gttcagaaat
    70861 ctatgtcaca cattttccat gtttggcctg tacaaaggct ttgttgcaag ctggtgtgaa
    70921 agggatcaat tatctccatg actatcgaaa tgatccttat gcccaagcgt tgatcgaaca
    70981 attaggtgta tctgtacacc aagttgcttt agactcacag catttttcaa aacttcaaaa
    71041 tgaattaaca ggaaaacatg tctagcgttt tagaaaggca tgttcgaaat cggttgattt
    71101 ttccggcaat tacgtcgatg attatctgtt tgttgtatta cactgacaat tggggttatc
    71161 gtttgcttct tgccggaatt tttttatggt tttcgctaaa agaaggacgt tttatcgcgt
    71221 acttgtgtat tttgtgtagc ataacggtat ccatttctta taggctacaa gagtattcat
    71281 ttttagagga aaaaacaaca tctgcgcaaa ttactgtatt tacagatacg attcgtgcaa
    71341 atggtaattt tttgacaatg gaaggaaggt tatcagagaa taaacaaaag ctccagcttt
    71401 cttatcaagt aaacacagaa gcagaattga aaacatggct taacttccga ggaaagggaa
    71461 tagaattgac tgctgaaggc gagttcatct ctccagcaaa aaagcggaat ctttataatt
    71521 ttgaccaaga agcttacttc aggaaccata gaatttctgg acggttccaa attcaaaaga
    71581 ttgaacagat caccatgcaa aatcactggc gaaactggct tcagagaaaa agaggatctt
    71641 ttatctcctt tgtccaatct gaatttccgc aaaaaacaag tgtatatatt aattctttat
    71701 tatggggcta taaagatgca ggattcagag aaccagaaga aatttttagg gagagtggtt
    71761 tgctgcatct gttcagtcta tcgggtctac acatccaatt ttatttaggg tggctgtatt
    71821 atttgtttcg acgtatcgga tggccactac acgtcagtat tattccgttg agtctactaa
    71881 ctatctgtta tgtttctatt gcaggaagtt ctatttctgt tttgcgtgct agtttgctgt
    71941 ttttattgcg attgctagtc aaattgctga ataagcatta ttccaccatg gacttatttg
    72001 cagttgtctt ttggcttctt ttactatttg atcctcgatt tctttttcat gcgggtggac
    72061 agcttagttt tttcatgagt tttttgttta tcctgatttc ttttgatgga gattggttga
    72121 aaaaaacggc ctctcacgtc ctgtttacta tgatcacgat gccgttgatt gtatggcatt
    72181 tttatgagtg gcctatttta ggtagtcttt ttacattact gattgcaccg gtattcaagt
    72241 ttctttttct tcctggtgtg ttatttctca cactcttcaa tcgctggctg ccggaaactt
    72301 tacttttgct gatagaagag ggattaatct tatttgagcg aataatcgat ttttcttcag
    72361 ggtcgtctct cattatagga cgtttgcccc ttgtgctatc tgggatgtat attttcggat
    72421 tactgatttg tatggatagg ttgaaagaac aacctgtgaa acacttgttt tatgttggtc
    72481 ttttttcttt tatttttttg actttgccat ttttacgctt ttcttcaacg atcgctttta
    72541 tcgatgtcgg tcaaggagac agtatctttt tgcaaagtcc ttttcgaaaa gaaacgattt
    72601 tgatcgatac tggaggtcag ttacactttg aaagagaaaa gtgggcgcaa ggtatgatac
    72661 gtcctcctgc tgaaagaaat atcgttccat atctaaaagg tcaggggata agtgtaatcg
    72721 ataaactcat cttgacacac gacgatacgg atcatgtggg agaattaccc acgttatctc
    72781 agcattttac tatcaaaaaa atttatatcg gttggggcgc tggacgaaat gagccattac
    72841 aaaggcattt atctgaagct caaaaaaatg gtactgagat cattgaaatc aaacatgggg
    72901 acaggatcag cggttattat gatctttatg tattgactcc ttttgaaaag ggagagggaa
    72961 gaaatgaaga ttcgattggt ctatggatgg aatataacaa taggcgcttt ttatttttag
    73021 gagatttgaa tcaagcaatg gaaaaacaat tgcttttgat ttatcctaat ctgaaagccg
    73081 atgtagtcaa attaggtcat cacggtagcc gtacgtcaag taacacagat tttctttccc
    73141 atattgaagc aaaacatggg attatatcct gcggcgtaaa taatcgttat ggtcacccgc
    73201 acagcgaagt attggagaca ctagaagaaa atcagataaa aacatggcga acggatcaac
    73261 aaggaatgat cacctatcgc tggcatccag tttttcatcc tcatgggcta gtggaaacaa
    73321 tgatagacta gtaattctca tctgctcatg gtaggataat ttttgaaagt ggtgagtaat
    73381 ttgagtatac aagcagagtt acaaaaaata cgtaaagaaa aacttgcatc ttgttacttg
    73441 attttaggaa cagaaaagtt tctccaagat caagttcgga cagaaattgt caaaaaaatc
    73501 caattagagg gcgaagatga cttaaatttt ttaagttttg acatggaaaa tgcaagttta
    73561 gatgaggtag tagctgaagc agagacgttg ccgtttttcg gagatcaacg gttagtattc
    73621 gtagagaatc cttatttttt aacaggtgaa aaagtaaaca atggaatcga acaaaatact
    73681 gatttattga cggcttattt gaaagaacca ttagaatcga ctgtattagt attctttgcg
    73741 ccatatgaaa agttggatga acggaaaaaa gtaacgaaac aattgaaaaa aacagcaatt
    73801 atcatcaatg tccaacagtt gaatgaaaaa gaagtacgtc aatatctgat gaatacctta
    73861 gagaattcct caatcaaaat ggaacgaagt gcaattgatt tattcttgag gttgaccgac
    73921 ttagatttat ccaaaatgat gagagagtta cagaaattgg tcctttatgg acaaaatcaa
    73981 cagcaaatca cggtaagaga agtagaagaa ttagttccta aaacgttaga acataatatt
    74041 tttgacatga cccaatatat tttaaaaggg aagacggaac aagctttgcg tttatacgaa
    74101 gatttagtta tgcaagggga agaaacaatc aaaattaatg cgattttgct ttctcaatta
    74161 cgtttatttt tacagacaaa atttcttgta aagattggtt atcagcaggc aaatattgct
    74221 gaaacattga aaatccatcc atatcgtgta aaacttgcca tgcaggaagt aaaaaaattc
    74281 gatgaacatt tgctggtaca gttgtttgat caattagttg agatggatta tcaaatcaaa
    74341 acgggacaaa tcgaaaaaga attaagtttt caactattcg ttttgcgcac agggcagttg
    74401 ttaagaaatc gataagaaga aagacgaggg caaagcatgc gggaaggtcg tttgtttttg
    74461 tccttttttt gacaaataaa aaaatcggcc gaagccgatt cttttattta gcgatttttt
    74521 tgcttaaacg agatttgtcg cggttagctt tgtttttgtg gattagacct tttgattcag
    74581 ccatatcaat agctttaaca gcttctttat ataacgcatc tacgttgtca gcacctgaag
    74641 ctacagcatc ttcaaatttt ttgattgcag tacgcatagc gcttgtttga gatgaatttt
    74701 tcacattagc gttttcgctt gtacgaacac gtttgattgc agattcaatg tttggcatta
    74761 gtttcacctc cgataactta agttcttacg cgtgttaccg cataattcaa cattcattat
    74821 tatacctaaa ggcagcgtgc tttgcaatat gaacatgaca agtttttttc cttaacagtc
    74881 ttttattagg attttttttc agtaaaaacg gatagtacaa gctgaaaaaa atcaaaaaga
    74941 cgctattgtg ggaggcaata gcgtcaaacc aaactagatt tttatttatc tatttaaaca
    75001 aagtttgaat gggaatgttt ggtactaagt tattatataa caaagagaac cgtttgcaaa
    75061 gttttttttg aaaagggata cgattccctg ttgttctttg tttttctatt aagaaactgc
    75121 agttatttta taaccagtat cctttgatca gtaaaggcta ttctggtgta ccgattattt
    75181 taatgtattc atcgatattt tttatcaaca ttttttttat gaccaactgg ttccgacggt
    75241 tccatttgcc acttacttcc agcacatatt tatttagggg caaacgtaag atatattttg
    75301 ccaaatagcg atctttaagc aggccattga tcacacggtc ctcaagctgc aagttgatcc
    75361 cagtcagcat cattggctgt tcttgtaaaa cgtacgtatc aattaaaaga ccttcaaaag
    75421 tttccacaag cgtcttcctt tcttttcaaa gtaacctgaa aacaggcact aattcttcca
    75481 ttttgatatt cgttgaagtg gatgcgatca ttctttcttt tgtccactgt aatctagtat
    75541 aacaaaaaag agcagaagag ccaaaaagaa aaaagagcat cgaattctat aggaagtctc
    75601 attggcacgg cctaaattat tacaaaacat tgattaaaaa aagcccctgc atcgcaggag
    75661 catcccctat atcgttttaa taggtcaatc aaaaagcagt atcaaacaca ttttgtatca
    75721 aatcaggaaa taatagataa gctaagccca gaatcaaaag taccgctaga agaaaccagc
    75781 cgattgttcc tatgaaatac tttaattttt cgaacattgt atcacctcgt tgtcagtata
    75841 tcacggatca gtaaattggg ggtgttaaga atctcctaaa atagacaaaa tttgttctat
    75901 tttcctaaag caaatacttg taagatacag taagtgatac cagaagcaat gaccggtccg
    75961 gcggcgattc ctcttaagaa gacaacacct aaaatcgtgc cgaaaacaag tgcaacagtg
    76021 atttgtggat cagaagcaat caatcctaca cccttggaag ataagacagc cactagccca
    76081 ccgcaaaaaa cagctaccca gccaataggg gatttaaagg cttctaatag atcacgtaga
    76141 ccgatttctc ctgttgcgat agggattaga atagccgctg tgatgatcgt caccccaata
    76201 ttgattcctt tgccttgaag ccaagggaaa aaggaacggg aggctggtat gagcttcata
    76261 atcaaaacaa aagctgccgc tatcatcaga ctttgatttt tagctaaaat tgctacaagt
    76321 aaaataattc ctaaaaaaag ccaactttcc atgaaatata ttcctcactt tcttcgaaac
    76381 aatcataaca tgtttttaga aagttacaaa agtaggaatt catccttcaa gacctattca
    76441 taagctgttt ttttcataaa ataaacaaaa tcataaaaaa acactttgct tatttgacag
    76501 aagacagccg cgctttgtat agtggacaag acttacattt ttttgaagaa tcagaaagat
    76561 caggtaaagg tcttagtaaa cgcaagccat tcagaataac caatattgtg cttccttcgt
    76621 gtcctacaac tccaagaggt agatttaaaa attgcaggaa gttagaagca atcaacaaga
    76681 gaataacaag aatcgaaaaa ataatatttt gtttgatgat ccgccgcatt tttaaagata
    76741 gccgatgact gtagacaaat ttatttaagt cgcttttcat taagacgatg tctgcgatat
    76801 ccatagcggc atctgtccct tgccccatag cgacacctaa agaagcggct gctaaagcag
    76861 gcgcatcatt gactccatca ccaaccatcg catttacttg gtaaagttca ttctcttttt
    76921 tgactagttg tgttttttct tccggagtac agcttgcata gtaatgttca atccctactt
    76981 gttcagcaat ggcctttgct gtgccagaat ggtcgccggt tatcatactt gtatggatgt
    77041 tttgggattt aaagtaggaa attacttgtt gggtatttgc ttttggaata tctagcagac
    77101 ctaaaacagc aattaactgc tgatctttag aaagataaat cacggttttg ccttgatttt
    77161 ccaaacgttc gatcatttcc gcaatctctt tgctgattat catcgtctca ggatcatatg
    77221 cgtgcttgcc aactttccat tgcgcaccta aataggtagt ttgtaatcca aaaccagtaa
    77281 tttcttctat tggtaagtat tggatttctt caggtattgt gcaatcgaaa tattgcaaaa
    77341 tcgcatgagc aagtggatgc gtcgtttttt gttccatagc aacaagaagt tgttgtgcca
    77401 aatccttttc atcaaagaaa aagctgtcag ttacaactgg ttttccttta gtgagcgttc
    77461 ctgttttatc aaaggcaatc gcttttaatt cagaaagctt ttctaaatgg ataccgcctt
    77521 tgattaaaat cccatttttt gcagaatttg aaagagcagc tagagaagct ggtgtagcag
    77581 atgcgacaag cgcacaagga gaagccacaa ctaataatac cattcctcga taaaagcttt
    77641 catcccaact ccaacctagg aaaaagtggg ggagaaggat cattagagga acagcaagca
    77701 aaatcaattt tacataatta ttttcgattc gttcgataaa tgaagctgtt tgagttggcg
    77761 tattctgcgc ttcttctact aattggataa tcttagcaaa gacagtttcg gaactcgttt
    77821 ttgttactcg aatcgtgatg ggatttcctt gattcagcgt tcctgcatac atctcatcgc
    77881 ctaaatattt ttctacaggc acagattcac cgcttaatgc agactcatcg atcgttgcct
    77941 gtgtgctttc taaaaagcca tctatcggaa cagctgctcc tttagcgaca aataccaagt
    78001 tatccacctt tagttgagaa acatctactt cttgcatttg tccattttct tttaataatt
    78061 gggctttttg tggttgaaga ttcatcaaag cagtaatttc tttttgactt ttattagttg
    78121 tgtattcctc taatgcaccg cttaaacaaa agatgaatgt caacattgct ccttcaaagt
    78181 aattaccgat caaacaggca ccaatagcag ctaaagccat caataaatcc acattcagtg
    78241 tccgatcatt ccacaattct ttcaagcctt ccgatgtttg tttatatcca ccgatgataa
    78301 tggcactgat ataaaaaagt ggggtgatgg taagagagaa tcggtcgaag ataaaaccga
    78361 agatcataaa taaaaggcag ccgattgttg ctgcaaaagc ttttttctga ttagtcatcg
    78421 ttattagacc tccttgtcaa aacaaggata gcataataaa aatgtaattg ataataataa
    78481 cagctaaatg agaacgataa tggttatcat ttggtgatta agcttgatgt tgtttttatt
    78541 atttataatg attattatta aagaaaataa aaaaccagaa catttctcaa ataagagaag
    78601 tgttctggtt ttttctacat tgcaataaac caataaccaa tcaaaatgat accaaggata
    78661 atacgatacc agccaaaagc ggtaaagtcg tttttcttca aatagcttag taagaatttg
    78721 atagctaaga cggaaaccac aaaagatacg aatgttccta caagaagaac aacagtttct
    78781 tccattttga atgaattccc ttcagctaaa tatttgacga tcttcaagcc gcttgcgcca
    78841 aacatgacag gaatccctaa gaaaaatgaa aactctgtag cgacaaaacg cgaagcacca
    78901 atcaagatag atcctaggat cgttgcgcca gaacgggatg ttccgggaac aagtgccaag
    78961 acttggaata acccaacaag aagagctgct tggtacgtaa agtcattcag agaagtccaa
    79021 cgaggtgttt tgtttttgtt gcgtttttcg acaataataa aggcaatacc gtaaacgatc
    79081 aaaacaatgg caactggtaa gaacttgtgg aaatttgctt ctaaccaatc atccaaaggc
    79141 aaaccaatga tgatggctgg tatgcaagca acgatcactt taaaccaaag tgtccacgta
    79201 tctttttttt ctaccgttga tttacttgga gaaaatgggt ttaacttgtg aaaataaaga
    79261 acgacgacag ccaagatcgc ccctaattgg ataacgacat tgaacatcga cataaattgt
    79321 gaactggcat ccagtttgat gaattcatct gctaggatca aatgaccagt actactgatg
    79381 ggcagccatt ccgttattcc ttcaataata ccgagaatca ctgctttgat aatatttgca
    79441 aaaaacataa attccttcct tcccaattaa gatacatctt atagtatacc gttatttttt
    79501 gagaaaccca atctgttttt taatattaag aaaaacttga gaaataaagc agataagtac
    79561 acgaagagaa aaaagaagac aaagccctcg ttcagacttt gccttttatg attctctggt
    79621 aaaaattaaa atatccccat tatagaaacg agtcgcgact atgtgttttc ccgttatcga
    79681 tataagacgt atcattgatg ccgtggatag aaaatcgacc gtttgcataa gtgacctttg
    79741 ttacgctgcc atttaaaagc ccagcacgaa caggctgttt aggatcgatc agattaagca
    79801 aaaaggcgat cgtcaaacca tgagatacga ctaaaacatt tccaccacca tttttttcgc
    79861 agtgatgggc gatatcttca aatcctgtcc atacacggtc tcgcaatgtt tcataagttt
    79921 ccgcccaccc agcggtatct aagttgtata cagcattagc aatttgttca aaagaaactt
    79981 ctgtggtaaa catttcatca tatgttttaa aattcaatac acgagggatc acaccccaca
    80041 tttccatgtc atatccacct tcaagagacc cgaaacacca ttctctaatc cttttttcaa
    80101 taaaataagg aatttctttt cccttagaat gttctcctag aataatacgg gcagtttcga
    80161 ttgcacgacc actgtcacta gaataagcaa atgaaaagtc gacatttttt aacccgcgac
    80221 ctaaataatg aatgccttct tgtccttgct ttgtgagggg tgtatcacac cagccttgta
    80281 ctcgttcaat tgtattgaac atcgtttttc cgtgtcgtac gatataaagt gtagtttctg
    80341 tcattttatt ctcctcctaa gtcgttttaa cgattgaaaa aaggatttgt ccttttttcc
    80401 tgttcaatcg tcgttgcatc gccatgtcct ggatagactg caaattcatc aggtaataca
    80461 aacagctggg tccgaatact atgaagtaat tgttctaaat tccctgtata cagatcggtt
    80521 ctaccgatac ttcctctaaa cagggcgtcg ccagaaacga caaaatcatc aaaaataaag
    80581 ctgacgcttc ctatagaatg ccctggggta gggacgacgc gaaaagacat gtttcctaaa
    80641 gtataagttt tcatttcaaa ttcatattct gcaggcgaga caataacatc agcaatatca
    80701 tcatgtctac cgagtccaga aagattcaaa atcggatcac ctagccattt ttgctctagt
    80761 gggctgacat aaactgggat ttgataatac gcgcgtaaag gttccactgc accgatatga
    80821 tcgtagtgag tatgggtaag caaaatcgct accggctgtt ggtttgtttt tttgatttct
    80881 tgtttgattc gttccgcatc ttctccaggg tcaatgatca aaagtgcttc ttcgttgtag
    80941 accaaataac agttttcttc aatcattcct gtttttaatc tttcgatatg catgtgcatt
    81001 cctccttgat agccaaaact tctttcatcc attagtataa cgcattcatt gctaggaaac
    81061 aaaaacaggt acttatttct ctttacttat ctgaattatc agactatatg aaaagtattt
    81121 ggatattcta aagagaagga aagtaagttt tcatagcatt ttaatatgtc cttgttacat
    81181 tagattcatc caaaaatcca aattctatat cctatatccc tgcctaatca gcagggtgtt
    81241 tttttatgtt tggaaagaga gctctttttg ctaaactagg ttttttcagg taatcttaga
    81301 gagaaagagg tggtggaaat gatcaaacag tcaaaaatat ctgtgcggca cttagtagaa
    81361 tttattttgc gacgtggaag tatcgacaat cgtaaaaaaa gtaaccatac tgcattagaa
    81421 ggagcgagaa tccaccgcaa gctccaaaaa gatgcgggag aaaactatga aaaagaagtc
    81481 tttttaaaaa caacagttca attagatgaa tattacctga tcgttgaagg ccgtgcagac
    81541 ggtattttca aaagagacgg tatttattat atagatgaaa tcaaaacctc cgaaccacga
    81601 tttgaagatt tagaaccaga acaagtggaa cttttctttc atcaagcaag ggtgtatgcc
    81661 tatatctata gtcaagaaca tgatttacaa gaaataaatc tgcaattgac ttacttccag
    81721 acggcagaag aagtgatcac gagaaaggtt gaacatcaga caagagagca gttagaaact
    81781 ttttttaaaa agctgactga agattataaa gaatggcttg tttttcaaga aaactggcgc
    81841 actgtacgca atgcctcttt gatggctttg aaattccccc atgatgagta taggaaaggt
    81901 cagcgtgaac tagcggtagc tgcttataaa acgatccgta cgaaacagaa attgtttgta
    81961 gaagcaccta ccggaacagg aaaaacaatc tctacgttat tccccgcttt gaaagctgta
    82021 ggggaagaag agggagaaaa gatcttttat ctaacggcta aaacaataac tagacaagta
    82081 gctgaagatg ctatgacagc attaaaagat acaggagctg aagtaaaaag tgtcactttg
    82141 acggcgaaag acaagatctg ctttttagat gagacgacct gtaatccaga tcagtgccca
    82201 tatgccaatg gttattacaa tcggattaat gaaggtttat gggatctttt gaatcatgag
    82261 aatcagatca ctcgtgaagt catcgaaact tatgcaagaa agcatacact ttgtcctttc
    82321 gaactatcat tagatgtcag tatctggtgt gacgtaatca ttggggatta caattattta
    82381 tttgatccaa ctgtttattt aagacgtttt tttgaagatg aaaaaaacga ggactatctg
    82441 tttttgattg acgaagcaca taatttggtg aatcgttccc gagagatgta ttcggcagaa
    82501 ctatcttatg aaaaaacgaa acgaagtaag gaagctatac caaaggaatt caaaaaactt
    82561 catcgccgtt tcaacaaact attaaaagaa tttgattcga tccgagaaat agcaaaagaa
    82621 gatcattggg attatcatca tcaaaaagca ccggctgaat ctttagtaaa ggcaggttat
    82681 caattaagcg aaaaaattaa agaatggctg gcagaatttc ctgagcaccc atcacaagaa
    82741 caattgcttc cttattattt tgatttgctt cattttttga aggtcagtga attttatgat
    82801 gatcactacg aaacaacagt cgaaaaaacg tatcgcgatc tgatagtaaa agagttttgt
    82861 attgatccaa gcttgtttct tgagcagtcg ttggataaag gaaaaagcag tattcttttt
    82921 tctgctagtt tttcaccact ctcttattat caggaaacac tggggggaca aaaaagtctg
    82981 gcttacaaac tgccgagtcc tttcccagaa ggaaaccagc aagttttcat cgcaaattac
    83041 ctagagacga cttatcgaaa aagggaacac agtctggcaa aattagtaga gacgattcat
    83101 gcttttgctg atggaaaggt cgggaattat ttcgttttct ttccttctta tcaatattta
    83161 gatcttgcgg tggaagcatt cagacagcaa tatcccgaca gcaatgtgct aatccaagaa
    83221 acggacatga atgaggaaga acgcgaacga tttttaacaa aatttcaaac aaatcccgct
    83281 gaaacattga ttggattttg cgtacttggc gggatttttt cagaaggaat cgatttgaga
    83341 ggggaccgat tgatcggcag tatgatcgta ggtgtaggtt tgccgcagat gaatcatgag
    83401 caggaactga tcaaatcata ttatgatgag aaggaacacc ttggatttgc ttacgcttat
    83461 cagcttcctg gaatgaacaa agtcttgcaa gctggtggtc gagtgattcg tggcatggcg
    83521 gatcaaggaa tcgttgtatt ggcagatcaa cgattttcta gtttttctta tcgacgttta
    83581 ttcccacaac attggcaaac agcaagagaa gtacgaagtg ttggggaatt ggaagaagga
    83641 atacagcgtt tttggttatc aaaagaagca gtaaatcaaa aaaacgagga atgacagacg
    83701 tcagcctcgt tttttgatta acgatagtta gtgaattgca actcgattgg taagtcaagt
    83761 ttacgtaata aagcaatcac agcttgtaga tcatcacggt tcttacctgt cactctaatc
    83821 tgatcttctt ggatttgtgc ttttactttc agtttttcat ttttgatagc tgtagtgatt
    83881 ttcttcgcgt tttcacgatc gattccgttg accaaatcgg cagtttgtcg agctttgcca
    83941 cctagagcgt gttctgattc ggaaaaatgg atatttttga ttggcacatt tcttttgatc
    84001 agcttaccaa ataatacatc tttgatctgt tcgattttga aatcatcatc gctcaataca
    84061 actagattgc tgttctctaa tttgatttct actgtagaat ccttgaagtc aaagcgattg
    84121 gacaattctt ttgttgtttg ctgaatcgca ttttttactt cttctgtatt gacttctgat
    84181 acaatgtcga agctagcatc ttttgccata ggaaccctcc tgatatacat ataaatattt
    84241 accatacatc tatcttatca taggattagg gcagattctt acctgtttgc taaaattctt
    84301 ctcatttgag ttcgaagtat tttattttaa tagataaact gttattctta catttggaat
    84361 accaaagtag gggagaggtg cttgtgagta aaattatgac tgcgtatcat aaaaatgaaa
    84421 gattaaagaa aatagtggtt attttgataa ccggattgac cgctgcggtc gctttaaatt
    84481 attttttgat tccagccaat gtcttttctg cagggatgaa tgggatcgct caaatcattt
    84541 cctcgctttt atatgaatgg tttcatatca agatagacac aggaacattt atttttcttt
    84601 tgaatatccc tgtgtttgta ttagggtttc tcaaagtagg aaaacgagca acgatcctta
    84661 gttttgtgaa tgttgtatgt gtatcggtga tgacgatgct gcttccagtc ggacagatca
    84721 ctgataatat tttgatgaat gccctagtag gcggtgtttt attaggtctt ggcgtaggat
    84781 tatctttaaa aatgggcttt acaactggtg ggatggatat catctctctt gtactttcac
    84841 aaacaactgg aaaaacagtc ggaaactaca tgctgattct aaatggtatc attgtagtca
    84901 tcgcaggctt cttctttaac tgggaaagtg ccttgtatac gattatttcc atttatgcaa
    84961 tgactcaagt aattgatgcc atccacacga gtcatcaaaa agtaacagca atgatcgtta
    85021 ccgtcaagcc agaagaggta acagaagaac tagcaaaacg gatggtacgt ggaatgacat
    85081 tactgccgtc tgtcggtggc tattcaaaaa aacaagggaa catgatcatg atggtcatca
    85141 cccgctacga aatgtatgat cttgatcaga tcgttcatga aatcgacgac gatgcattta
    85201 tcaatatttt accaactcat tcagtatttg gccggtttgc aaatgaaaac gaacaaaaaa
    85261 tgtatcgaac aactggcgta ttgccagaaa taaaaaatcg ttcacaaaaa aaatgaggaa
    85321 tcaggtttat tttagaataa atttaatcta ttacatctaa taagaacatt tttataaatt
    85381 taaacgagaa tcttacttct aaattctcat ttacaagcag ctaaaaaaag agtatgataa
    85441 ataaaaatcg tgttaaggag tgtcgtacga tgagcgaagc aaaccaagaa cggtctggac
    85501 aagaaataga actaatcaaa gaacgtattc ttgctgcctt ggaaatggtg attgatcctg
    85561 aattaggaat cgacatcgtc aatttaggct tgatttatga tatagaattc aatcctgaaa
    85621 atggagaaac agtcattaag atgactctaa caactatggg ctgtccatta gcagatattt
    85681 taacagaatc tatccatgac gcattaaaag aagtgccaga agtaacgaaa gcagaagtca
    85741 aactagtctg gtatccagca tggacgacag ataagatgag ccgttatgca cggattgcgt
    85801 tggggatacg atagaaatct tggctgacta gctatgagaa gcaaatagga aaaacaaaaa
    85861 agccttttat cctttctaga agaaaagaga taaaaggttt ctttgtttat aaaattttgt
    85921 ctgctatatt ataagttaat taaataaatg tgttctattg ataaaggaca ttcaaatccc
    85981 tttccttttg gaatccttct tttttacatc agtttgattt tcgtatagta ttctttctca
    86041 tcttcacgat aaatcgcagc cccatttttt tgttgtgctt taagactgcc aagatttttt
    86101 ttatttacag acaaaagtgc ctcatcaatg ccgatttttt ttgcctcttg tagtactaat
    86161 gctaatcctt gtgtggcata tcctttttta cgataattag gggagatgcc gtaaccaata
    86221 tggccagcgc cgtttcttaa tgtttcgttc agtttatggc gcaaattaaa aattcctaca
    86281 tactcatgtt catcactttc taaaataaag acggttgcgg gaacgtaact ctcaggaaga
    86341 tcgattccta aagacgtttt ttcgcatttt tttacataat ctaaaaattc agcaaatgta
    86401 tagccataag cattgttgat aaatccactc tcatttggtc caaagctagt ttgtagctga
    86461 taagctttct ttaaatctgc ttcccatagt ttgatcagtt tcatcgtatt cacctcttta
    86521 agtaacctta ttcatttgtt ttctactata gcactattgt tgtaaatagc catgcctatt
    86581 tttatttatt gtgtcatatc gtattaagaa tcatcgaaca atacaaatat gaattacaat
    86641 aaaaaaatta tttgaagttc gttcattcgt tacttatgat ctctagaaga aagaaaacgt
    86701 gaattacttc agcgtctaga attccagaag gatagtaatc aacagaagaa ataatcaata
    86761 tccaaatgaa agaagatagc tgaatcgaga aaaagaggaa aaaagaaatg aagaaaaaaa
    86821 taaaatagtt actaatccca gagtcgttcg tttaacattg aaatcgatca tatggataaa
    86881 acagattttt tcaccaaccc tcaatagatg atggagttgc tcggatgaat tatttgtgta
    86941 gatggcataa gggagggcgt acagaaatga aaaagaacaa aaatatgttc ttgacaaaaa
    87001 acacatgtaa tcctaaacta aaagatgtga tgcggctatg gcggaattgg cagacgcgct
    87061 agcttcaggc gctagtgagg gtgacctcgt ggaagttcga gtcttcttag ccgcataatt
    87121 tgttttttta taaagagaag gtacacctgg agcgatgaga aagaaaataa catattatct
    87181 aaaagaatat aggaaaaatt ttaaacaacg gaaccagatt caaataaatc aaaaaaaatt
    87241 tgtgtgaagg tgggacagtt taaaacctaa tagattgatt caaatagtag atttatagat
    87301 tctgatacaa gaaatactgg caaacgatag ttaaggaata aagactaaac ttaaactcaa
    87361 aaagaggtca tgcgaaagaa taaatcgcat gacctcttac tatattttga atgtgtttaa
    87421 acgttcaaat aatgaatctt agtaccaacc gtttgcttcc cagaatgctt tcgccgcttc
    87481 ccaagaacca taacgtgaag taacatattg ttctgctact ctttcttggt ttgcagcaga
    87541 gtagtcacca tttaagtaag aagaatctaa ttggtaacgg ccgatgtaac gtccgttcgt
    87601 tgctgtgtaa gaaccgcttg attctttttg tgcgatccat tcttttgcag agcttgtact
    87661 tgctggagta gcagcagttt ctgttacagc aggagcaggt tgtgtttcag caacaggcgc
    87721 tgcttgtgtt tccgtttgaa ccgtttcttg tacaacaggt tgttcagctt gaacaggttc
    87781 agcttggact ggtgcttctt gaacggctgc ttgaggttca gcagctgctt gtgcagagcc
    87841 ttctgttggg attgttaatt gttgtcctga gta
//
LOCUS       DAZKCH010000003        85094 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000003 DAZKCH010000000
VERSION     DAZKCH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 85094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.003"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            148..666
                     /locus_tag="ACG84X_000183"
     CDS             148..666
                     /locus_tag="ACG84X_000183"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFP9126093.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            794..1477
                     /locus_tag="ACG84X_000184"
     CDS             794..1477
                     /locus_tag="ACG84X_000184"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFP9126094.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1786..1859
                     /locus_tag="ACG84X_000185"
     tRNA            1786..1859
                     /locus_tag="ACG84X_000185"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1820..1822,aa:Arg,seq:tct)
     gene            2018..2377
                     /locus_tag="ACG84X_000186"
     CDS             2018..2377
                     /locus_tag="ACG84X_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFP9126095.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2500..4131
                     /locus_tag="ACG84X_000187"
     CDS             2500..4131
                     /locus_tag="ACG84X_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFP9126096.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4193..4834)
                     /locus_tag="ACG84X_000188"
     CDS             complement(4193..4834)
                     /locus_tag="ACG84X_000188"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFP9126097.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5020..5096
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5116..5424
                     /gene="rplU"
                     /locus_tag="ACG84X_000189"
     CDS             5116..5424
                     /gene="rplU"
                     /locus_tag="ACG84X_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFP9126098.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5451..5795
                     /locus_tag="ACG84X_000190"
     CDS             5451..5795
                     /locus_tag="ACG84X_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFP9126099.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5808..6101
                     /gene="rpmA"
                     /locus_tag="ACG84X_000191"
     CDS             5808..6101
                     /gene="rpmA"
                     /locus_tag="ACG84X_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFP9126100.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6535..9342
                     /locus_tag="ACG84X_000192"
     CDS             6535..9342
                     /locus_tag="ACG84X_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9126101.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9533..10024
                     /locus_tag="ACG84X_000193"
     CDS             9533..10024
                     /locus_tag="ACG84X_000193"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFP9126102.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10127..11116
                     /locus_tag="ACG84X_000194"
     CDS             10127..11116
                     /locus_tag="ACG84X_000194"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFP9126103.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11149..11952
                     /locus_tag="ACG84X_000195"
     CDS             11149..11952
                     /locus_tag="ACG84X_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFP9126104.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11973..12887
                     /locus_tag="ACG84X_000196"
     CDS             11973..12887
                     /locus_tag="ACG84X_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9126105.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12970..13344
                     /locus_tag="ACG84X_000197"
     CDS             12970..13344
                     /locus_tag="ACG84X_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFP9126106.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13483..13728
                     /locus_tag="ACG84X_000198"
     CDS             13483..13728
                     /locus_tag="ACG84X_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFP9126107.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13900..14964
                     /locus_tag="ACG84X_000199"
     CDS             13900..14964
                     /locus_tag="ACG84X_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFP9126108.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15210..15635
                     /locus_tag="ACG84X_000200"
     CDS             15210..15635
                     /locus_tag="ACG84X_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFP9126109.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15628..16077
                     /gene="nusB"
                     /locus_tag="ACG84X_000201"
     CDS             15628..16077
                     /gene="nusB"
                     /locus_tag="ACG84X_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFP9126110.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16174..17028
                     /locus_tag="ACG84X_000202"
     CDS             16174..17028
                     /locus_tag="ACG84X_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFP9126111.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17029..18366
                     /gene="xseA"
                     /locus_tag="ACG84X_000203"
     CDS             17029..18366
                     /gene="xseA"
                     /locus_tag="ACG84X_000203"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFP9126112.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18371..18595
                     /locus_tag="ACG84X_000204"
     CDS             18371..18595
                     /locus_tag="ACG84X_000204"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFP9126113.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18597..19487
                     /locus_tag="ACG84X_000205"
     CDS             18597..19487
                     /locus_tag="ACG84X_000205"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFP9126114.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19496..20314
                     /locus_tag="ACG84X_000206"
     CDS             19496..20314
                     /locus_tag="ACG84X_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFP9126115.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20421..20870
                     /locus_tag="ACG84X_000207"
     CDS             20421..20870
                     /locus_tag="ACG84X_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFP9126116.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20888..22570
                     /gene="recN"
                     /locus_tag="ACG84X_000208"
     CDS             20888..22570
                     /gene="recN"
                     /locus_tag="ACG84X_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFP9126117.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22625..22741)
                     /locus_tag="ACG84X_000209"
     CDS             complement(22625..22741)
                     /locus_tag="ACG84X_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFP9126118.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22814..23770)
                     /locus_tag="ACG84X_000210"
     CDS             complement(22814..23770)
                     /locus_tag="ACG84X_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFP9126119.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23941..24309
                     /locus_tag="ACG84X_000211"
     CDS             23941..24309
                     /locus_tag="ACG84X_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFP9126120.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24479..24910
                     /gene="mraZ"
                     /locus_tag="ACG84X_000212"
     CDS             24479..24910
                     /gene="mraZ"
                     /locus_tag="ACG84X_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFP9126121.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24931..25890
                     /gene="rsmH"
                     /locus_tag="ACG84X_000213"
     CDS             24931..25890
                     /gene="rsmH"
                     /locus_tag="ACG84X_000213"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFP9126122.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25895..26296
                     /gene="ftsL"
                     /locus_tag="ACG84X_000214"
     CDS             25895..26296
                     /gene="ftsL"
                     /locus_tag="ACG84X_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFP9126123.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26297..28489
                     /locus_tag="ACG84X_000215"
     CDS             26297..28489
                     /locus_tag="ACG84X_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFP9126124.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28515..29477
                     /gene="mraY"
                     /locus_tag="ACG84X_000216"
     CDS             28515..29477
                     /gene="mraY"
                     /locus_tag="ACG84X_000216"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFP9126125.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29491..30852
                     /gene="murD"
                     /locus_tag="ACG84X_000217"
     CDS             29491..30852
                     /gene="murD"
                     /locus_tag="ACG84X_000217"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFP9126126.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30878..31966
                     /gene="murG"
                     /locus_tag="ACG84X_000218"
     CDS             30878..31966
                     /gene="murG"
                     /locus_tag="ACG84X_000218"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFP9126127.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31981..33201
                     /locus_tag="ACG84X_000219"
     CDS             31981..33201
                     /locus_tag="ACG84X_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFP9126128.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33357..34682
                     /gene="ftsA"
                     /locus_tag="ACG84X_000220"
     CDS             33357..34682
                     /gene="ftsA"
                     /locus_tag="ACG84X_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFP9126129.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34705..35946
                     /gene="ftsZ"
                     /locus_tag="ACG84X_000221"
     CDS             34705..35946
                     /gene="ftsZ"
                     /locus_tag="ACG84X_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFP9126130.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35963..36640
                     /locus_tag="ACG84X_000222"
     CDS             35963..36640
                     /locus_tag="ACG84X_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFP9126131.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36654..37253
                     /locus_tag="ACG84X_000223"
     CDS             36654..37253
                     /locus_tag="ACG84X_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFP9126132.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37334..37555
                     /locus_tag="ACG84X_000224"
     CDS             37334..37555
                     /locus_tag="ACG84X_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFP9126133.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37604..38386
                     /locus_tag="ACG84X_000225"
     CDS             37604..38386
                     /locus_tag="ACG84X_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFP9126134.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38407..39114
                     /locus_tag="ACG84X_000226"
     CDS             38407..39114
                     /locus_tag="ACG84X_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFP9126135.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39376..42174
                     /gene="ileS"
                     /locus_tag="ACG84X_000227"
     CDS             39376..42174
                     /gene="ileS"
                     /locus_tag="ACG84X_000227"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFP9126136.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42223..43749)
                     /gene="zwf"
                     /locus_tag="ACG84X_000228"
     CDS             complement(42223..43749)
                     /gene="zwf"
                     /locus_tag="ACG84X_000228"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFP9126137.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43764..44411)
                     /locus_tag="ACG84X_000229"
     CDS             complement(43764..44411)
                     /locus_tag="ACG84X_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFP9126138.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44595..44924)
                     /locus_tag="ACG84X_000230"
     CDS             complement(44595..44924)
                     /locus_tag="ACG84X_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFP9126139.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45101..45829
                     /gene="sfsA"
                     /locus_tag="ACG84X_000231"
     CDS             45101..45829
                     /gene="sfsA"
                     /locus_tag="ACG84X_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFP9126140.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45845..46858
                     /locus_tag="ACG84X_000232"
     CDS             45845..46858
                     /locus_tag="ACG84X_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9126141.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46858..48135
                     /locus_tag="ACG84X_000233"
     CDS             46858..48135
                     /locus_tag="ACG84X_000233"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFP9126142.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48198..50900
                     /locus_tag="ACG84X_000234"
     CDS             48198..50900
                     /locus_tag="ACG84X_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9126143.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYDQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51052..51369
                     /locus_tag="ACG84X_000235"
     CDS             51052..51369
                     /locus_tag="ACG84X_000235"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9126144.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51399..51719
                     /locus_tag="ACG84X_000236"
     CDS             51399..51719
                     /locus_tag="ACG84X_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFP9126145.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51827..53287
                     /locus_tag="ACG84X_000237"
     CDS             51827..53287
                     /locus_tag="ACG84X_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9126146.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53355..53576
                     /locus_tag="ACG84X_000238"
     CDS             53355..53576
                     /locus_tag="ACG84X_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126147.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53607..53789
                     /locus_tag="ACG84X_000239"
     CDS             53607..53789
                     /locus_tag="ACG84X_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFP9126148.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53789..54202
                     /locus_tag="ACG84X_000240"
     CDS             53789..54202
                     /locus_tag="ACG84X_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFP9126149.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54325..55506
                     /locus_tag="ACG84X_000241"
     CDS             54325..55506
                     /locus_tag="ACG84X_000241"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9126150.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55577..55741)
                     /locus_tag="ACG84X_000242"
     CDS             complement(55577..55741)
                     /locus_tag="ACG84X_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126151.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55895..55968
                     /locus_tag="ACG84X_000243"
     tRNA            55895..55968
                     /locus_tag="ACG84X_000243"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55929..55931,aa:Arg,seq:cct)
     gene            complement(56037..57176)
                     /locus_tag="ACG84X_000244"
     CDS             complement(56037..57176)
                     /locus_tag="ACG84X_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9126152.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAGLLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            57348..57482
                     /locus_tag="ACG84X_000245"
     CDS             57348..57482
                     /locus_tag="ACG84X_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126153.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(57475..58110)
                     /locus_tag="ACG84X_000246"
     CDS             complement(57475..58110)
                     /locus_tag="ACG84X_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126154.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58223..58858)
                     /locus_tag="ACG84X_000247"
     CDS             complement(58223..58858)
                     /locus_tag="ACG84X_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFP9126155.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58892..59353)
                     /locus_tag="ACG84X_000248"
     CDS             complement(58892..59353)
                     /locus_tag="ACG84X_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFP9126156.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(59483..59914)
                     /locus_tag="ACG84X_000249"
     CDS             complement(59483..59914)
                     /locus_tag="ACG84X_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFP9126157.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(59932..60252)
                     /locus_tag="ACG84X_000250"
     CDS             complement(59932..60252)
                     /locus_tag="ACG84X_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9126158.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            60551..61327
                     /locus_tag="ACG84X_000251"
     CDS             60551..61327
                     /locus_tag="ACG84X_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFP9126159.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            61342..61545
                     /locus_tag="ACG84X_000252"
     CDS             61342..61545
                     /locus_tag="ACG84X_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126160.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61561..61899
                     /locus_tag="ACG84X_000253"
     CDS             61561..61899
                     /locus_tag="ACG84X_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFP9126161.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            61886..62065
                     /locus_tag="ACG84X_000254"
     CDS             61886..62065
                     /locus_tag="ACG84X_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126162.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(62108..62578)
                     /locus_tag="ACG84X_000255"
     CDS             complement(62108..62578)
                     /locus_tag="ACG84X_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126163.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            62665..63363
                     /locus_tag="ACG84X_000256"
     CDS             62665..63363
                     /locus_tag="ACG84X_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFP9126164.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            63541..63882
                     /locus_tag="ACG84X_000257"
     CDS             63541..63882
                     /locus_tag="ACG84X_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126165.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            63875..64546
                     /locus_tag="ACG84X_000258"
     CDS             63875..64546
                     /locus_tag="ACG84X_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFP9126166.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            64552..65244
                     /locus_tag="ACG84X_000259"
     CDS             64552..65244
                     /locus_tag="ACG84X_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFP9126167.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            65241..65990
                     /locus_tag="ACG84X_000260"
     CDS             65241..65990
                     /locus_tag="ACG84X_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126168.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            66002..66271
                     /locus_tag="ACG84X_000261"
     CDS             66002..66271
                     /locus_tag="ACG84X_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126169.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            66277..66441
                     /locus_tag="ACG84X_000262"
     CDS             66277..66441
                     /locus_tag="ACG84X_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126170.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            66434..66733
                     /locus_tag="ACG84X_000263"
     CDS             66434..66733
                     /locus_tag="ACG84X_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126171.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            66733..67035
                     /locus_tag="ACG84X_000264"
     CDS             66733..67035
                     /locus_tag="ACG84X_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFP9126172.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            67075..67440
                     /locus_tag="ACG84X_000265"
     CDS             67075..67440
                     /locus_tag="ACG84X_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126173.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            67930..68070
                     /locus_tag="ACG84X_000266"
     CDS             67930..68070
                     /locus_tag="ACG84X_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126174.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            68067..68249
                     /locus_tag="ACG84X_000267"
     CDS             68067..68249
                     /locus_tag="ACG84X_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126175.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            68262..68456
                     /locus_tag="ACG84X_000268"
     CDS             68262..68456
                     /locus_tag="ACG84X_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126176.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(68489..68701)
                     /locus_tag="ACG84X_000269"
     CDS             complement(68489..68701)
                     /locus_tag="ACG84X_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126177.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            68829..69029
                     /locus_tag="ACG84X_000270"
     CDS             68829..69029
                     /locus_tag="ACG84X_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126178.1"
                     /translation="MKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDKY
                     LGEGFCGDSLFDDERILKEETE"
     gene            69026..69298
                     /locus_tag="ACG84X_000271"
     CDS             69026..69298
                     /locus_tag="ACG84X_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH/PUA domain-containing protein"
                     /protein_id="HFP9126179.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            69299..69484
                     /locus_tag="ACG84X_000272"
     CDS             69299..69484
                     /locus_tag="ACG84X_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126180.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            69462..69818
                     /locus_tag="ACG84X_000273"
     CDS             69462..69818
                     /locus_tag="ACG84X_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126181.1"
                     /translation="MKKVNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVL
                     KIEQNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIR
                     GGVCEISLVKRLPRTR"
     gene            69778..70254
                     /locus_tag="ACG84X_000274"
     CDS             69778..70254
                     /locus_tag="ACG84X_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFP9126182.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(70400..71128)
                     /locus_tag="ACG84X_000275"
     CDS             complement(70400..71128)
                     /locus_tag="ACG84X_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HFP9126183.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            71176..71454
                     /locus_tag="ACG84X_000276"
     CDS             71176..71454
                     /locus_tag="ACG84X_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126184.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            71456..71842
                     /locus_tag="ACG84X_000277"
     CDS             71456..71842
                     /locus_tag="ACG84X_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HFP9126185.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            71839..72219
                     /locus_tag="ACG84X_000278"
     CDS             71839..72219
                     /locus_tag="ACG84X_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFP9126186.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            72331..72783
                     /locus_tag="ACG84X_000279"
     CDS             72331..72783
                     /locus_tag="ACG84X_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFP9126187.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            72780..74507
                     /locus_tag="ACG84X_000280"
     CDS             72780..74507
                     /locus_tag="ACG84X_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFP9126188.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            74571..75758
                     /locus_tag="ACG84X_000281"
     CDS             74571..75758
                     /locus_tag="ACG84X_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFP9126189.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            75730..76299
                     /locus_tag="ACG84X_000282"
     CDS             75730..76299
                     /locus_tag="ACG84X_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFP9126190.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            76312..77676
                     /locus_tag="ACG84X_000283"
     CDS             76312..77676
                     /locus_tag="ACG84X_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFP9126191.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            77678..77959
                     /locus_tag="ACG84X_000284"
     CDS             77678..77959
                     /locus_tag="ACG84X_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFP9126192.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            77937..78263
                     /locus_tag="ACG84X_000285"
     CDS             77937..78263
                     /locus_tag="ACG84X_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFP9126193.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            78253..78591
                     /locus_tag="ACG84X_000286"
     CDS             78253..78591
                     /locus_tag="ACG84X_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126194.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            78581..78946
                     /locus_tag="ACG84X_000287"
     CDS             78581..78946
                     /locus_tag="ACG84X_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFP9126195.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            78953..79579
                     /locus_tag="ACG84X_000288"
     CDS             78953..79579
                     /locus_tag="ACG84X_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFP9126196.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            79579..80043
                     /locus_tag="ACG84X_000289"
     CDS             79579..80043
                     /locus_tag="ACG84X_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126197.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            80238..82547
                     /locus_tag="ACG84X_000290"
     CDS             80238..82547
                     /locus_tag="ACG84X_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFP9126198.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            82559..83263
                     /locus_tag="ACG84X_000291"
     CDS             82559..83263
                     /locus_tag="ACG84X_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFP9126199.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            83260..>85094
                     /locus_tag="ACG84X_000292"
     CDS             83260..>85094
                     /locus_tag="ACG84X_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFP9126200.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT        28688 a        13999 c        17876 g        24531 t
ORIGIN      
        1 tttataataa aaaatgagat aaagatgagg aaatagaatt agaaacatat aattattaaa
       61 gggaaacatt tttacagcta taatttgaaa aaatttatcg ttattatatg attaagaagg
      121 attgaataaa gaaagaagtt gaaaacgata cctgattaca aaaaaataac ttttataagt
      181 tctataacgt tgattatatt tttaattctt attcttctcg tcgtcttggt tccccgaatt
      241 tttggtttga ctccttatat tattgaggac aaagaaatga gtccatatta tgcacaagga
      301 aatctgatat atgtacgacc gaaaaataca aatgagattt tagtcggaga tattattaca
      361 tattatgaaa attcaggaaa aaaaatctcg acgcgtcgcg taatagccgt tgaaaacaac
      421 cacgaagatt tttatacaaa agctgataca aagacttata ttgagcctgg agtagtaaaa
      481 aagagaaata ttatcggtag tcccatcttt cagattccat atattggact agtcctttca
      541 aaaacggcgt ttgcatggat tcaggggtta ttctttacga ttgctttttg cctaacagga
      601 atcacagcat ggaatacctt tgtagagttg aaaaagaagc ggagacgaac acagaaattt
      661 ttgtaagaat gttaaaaaca taaatgtatt ccagagatcc aacgactctt ctgaacatga
      721 aacacgagaa aacactcatg cagcttgtag atttagtcag ttgttcgtat aatgtgtgaa
      781 gaggaggagt agtatgcgca atgaaatgat gcatcgtcct gtagtcaaag aagaactatt
      841 ggattttatg cgtacccagc aaaaaaaatt accgggtgag ctaggcaaac tggaagaaga
      901 agctcatgta gcagaagtac cagttattcc ccatgaaaca gttgtatttt tgaaattttt
      961 acttggacag cttcagcctg aacgaatctt ggagatcgga gcagctatcg gtttttcatc
     1021 aagtgtcatg gccacgacaa tcggagaaaa cgctcatgtt acgacaattg atcgtttcga
     1081 tgtcatgatc gagaaagcta aaaaaaacta tgaacgtcta ggactgacag ataaagtgac
     1141 tttgcttgaa ggtcaagcag cagatatctt gccggagttg tctggtccgt atgactttat
     1201 ttttatggat agtgcaaaat caaaatatat tgaattttta cctgaatgct tacgtttgtt
     1261 aagaaaaggt ggcgttttga tggtagatga catcttccaa ggaggaacga tcttgctccc
     1321 agatgaagag attccccgtg gcaaacgagc tatccatcgt aaattaaatg aatttcttcg
     1381 tgttgtgatg gatcatcccg atttgacatc gacaatcttg ccattaggtg atggtgtgat
     1441 cttaatgaca aaggaatcag aaacaatcga gttgtgatac atgattatgg cagcctgtag
     1501 ataatcgatt gaatcgaggg ctcaattcga acttgatgta aaagtttcta tatttgtaag
     1561 tcaattaaag gatacaggaa atctaaataa acaggagtag catgaagtca atgtagctcc
     1621 tgttttcaat tgataacctt agaacagctg aaggagaatg tctcgtttta aaagattgat
     1681 ttagtagttg ggccaaaata attcattatt tgctaattaa ataactattt cgtattgaca
     1741 gaagcaattt aattatctat aattattgat gttccgctga ttcttgtcat agtagctcag
     1801 ctggatagag catccgcctt ctaagcggac ggtcgggggt tcgaatccct cctgtgacgc
     1861 taaaaaaccg ttagaaactg aggtttctaa cggtttttct ttgttttttg tgccaatatt
     1921 gtttgttttc aaaggcaaat aaaataaaaa aacatcctta tcgagtacaa ttataaggag
     1981 caaaaaaata aaactcatca gaaaagagga agaagatatg acgatactat ctagaatttt
     2041 agtgactcta gttgcaattg aattttttta tatcatgtat atcgaaacgg tgagaactga
     2101 ttctgacacg acaagtaggg tttttaaaat gagtaaagaa gagttaagca gaaaatctgt
     2161 tcaaacattg tttaagaacc aaggagtgta caatggacta ttaggagtgg gactacttta
     2221 tggagcttat ctttcttccg catctaaaga aatcacaagt atgctattaa tatctatttt
     2281 ttttgttgca ttatatggca gtttgactag cgatcgttgg attttactca aacaaggtgg
     2341 gctagctctg ttggcattgc tttctatttt cttataaata tagaaaaaat aagaatttat
     2401 ctaacaggaa actttgtgaa aaatattact ttatctcatg aaatatgata ttctaatgaa
     2461 tggtatttta gaaaatttca tgaaaaagga gttagatagg tgttcaaaaa ttatgtttcc
     2521 tcactaaaaa aagaattttc aggttatgat ctttcaagat ttcagaaaga tcttttggct
     2581 gggatcacag tagctgctgt agcattgcct ttagccttgg cttttggggt atcaagcgga
     2641 gctgatgcgg ccgcaggttt gattacggct atcattgccg gtatcgttat tggcggttta
     2701 tcaggcggtt tttatcaaat atcaggtccg acaggtgcga tggcagctat cttgatgtct
     2761 attgcggcaa caaagggaat gcaaggtgta ttgcttgcta cttttttagc gggtctattt
     2821 ttacttgcag caggactttt ccgattagga acactgactt cttttatccc agcacccgta
     2881 attacggggt ttacttcagg tattgctatc attattgcat taggtcagat cgataattta
     2941 tttggtgttc actcggaagg tacaaacgtt attgaaaaac taagtagtta tcaaacgata
     3001 ggatttccga taaacacagc ctctttgatc atgggagggc tagtcatttt agggatgttt
     3061 atctatccaa aaaaatgggc gaaacgaatg cctagttcgc tgctggctat cattttggca
     3121 acagcagtta tgctattgtt ccatttacca gtagcaactg tgggtaagat tccacaaaca
     3181 ttgatcagta gtaatcgttt gaatatggga gattttagct tttctgcctt gcaacaagtg
     3241 gcagttccag ctattagcat tgctttatta ggaatgattg aaagcttgct atgtggtgct
     3301 tcggctggcc gaatggcaaa taagccctta gatagcaatc aagaattaat ggcgcaagga
     3361 attggaaatc tgttgcttcc tttctttggc gggattcctg ctactgcggc catcgcccgt
     3421 acaagcgtgg ccatcaaatc tggtgcacaa actagattag ctggtatgat acatgcagtt
     3481 gtcttactgc tctccatgct tgtttttgcg ccagtgatgt cacagattcc aatgccagca
     3541 cttgcaggtg ttttgattgt gacggcttgg cgtatgaatg aatgggaaac gatcaaggag
     3601 ctatttacta ataaatattg gtcagcagtt ctattgttta tccttacgat gatttgtaca
     3661 gttatctttg atttaagtat tgctatcgtg atcggggtga tcggcggctg tgtatttttt
     3721 gttgtcaaaa gcgctgctat cacgatttca ttagaaacga tcgattggca aagaatgggg
     3781 ctgccagaaa cggaaaagct gaataactgg acagtagtgt atattagtgg tccactgttt
     3841 tttatgtctt cagaaaaact caaaaataaa ttggaagaac taaatcatca cgatggtgtc
     3901 attttctcca tgcgaggcgt accaagtatt gatttgacgg cacgtgcagt ttttgatgaa
     3961 tttcaagaaa aagcagagca aagaggacaa acgattatct atacttcctt gcagccagaa
     4021 gtagaaaaac aactttctca cttgtgggaa catacattca cgcatcaaca tcaaacagtt
     4081 gctcatgcgt tgacagcttt acatgcgaaa tatactgcaa ttagccatta aaacaatgaa
     4141 aaagaacaga caagactgta aactgaagat tttatggtct tgtctgttct ttttaatatt
     4201 gctgtaaaag tgaagctagt acttgccagt cttgatggat aacaggtaca agggagcgat
     4261 tgtagaaaat agctgctgga tgaaaaagtg gaagaattcg atagtttttt tctgaccatt
     4321 cgtaggcatc cttttgttct gttaattgta agacaggccc tgtatagagt tgaccatgat
     4381 ttttggtaac cgtatattct ttgccaagta aacgttgaag accaatgttt ccaagtgtcg
     4441 caattaattt tggctggacc ttcatcagtt cgtaatccaa tattggtgca tgcgcaaata
     4501 cttcggaacg agtaggtgtc cgatttggat aaacagtttc tgactgttgt gtccgtttat
     4561 tgatccgatg agtcacgcga tacgggcggc tccttacagc actggtgata tacacctctt
     4621 ctcgtgttaa gccagttgaa gaaagtgcct gcatcaattc ttttccagct tgaccgctaa
     4681 aaggaacatg cgtatcaatc tctgttttcc ctggggcttc tcccacgagc atcagtttag
     4741 gatgaagagg tccttgccca gcgataaatc cttctacagg acggccgttc attcttaaag
     4801 aagcttcttg tatcagttct tttgggtatt ccatttatgc tcctcctttt tcttttatta
     4861 taagaataaa agaaacacaa tgcgactatt ttatttggta gaactgtgag gatagaaaag
     4921 cagaagtatt gcttgaattt ttgttttact ttttgatttt aaatttagtt gactaacggt
     4981 tgctgttctg gtaagctagt actgttgtaa ttgtggactc cacagctaca accgctcaga
     5041 acaagtaata agcacagcat atgctgtcac ttcggatggc gagtctaagt atatcagaag
     5101 gaggtgcttt atagcatgta cgcaattatt aaaactggtg gtaaacaagt aaaagttgaa
     5161 gtgggacaag caatctatgt tgaaaaactt gacgttgaag caggagaaaa agttgttttt
     5221 gacgaagtta tcttagtagg cggagaatct acaaaagtag gcgctccaac tgttgcaggt
     5281 gcaactgttg aaggtactgt tgaaaaacac ggcaaacaaa agaaagtcgt tactttcaaa
     5341 tacaaaccta aaaaacattc acaccgtaaa caaggtcatc gtcaaccata tacaaaagtg
     5401 gttatcgacg cgatcaacgc ttaatagcgt ttgagaaaga aggcctatat atgatcaaag
     5461 gaacatttaa gcgaaatgac gcaggtcaga tcgtttcatt cactttgacc gggcatgctg
     5521 atgctggtcc ttatggaagt gatatcgttt gtgcgggtgt ttctgcgtta gcgatcagca
     5581 ctgtcaacgg gattgcctca ttagccggtt ttgagccgat tgttgaaatg aatgaagaag
     5641 aaggcggtta tctttatacc gaagtcactt caggaatgac acaagaacaa aacaatattg
     5701 ctgagattct attagaaaat cttttattag gattacaatc gatagaagct gaaaactcag
     5761 aatatatcca aattaaaaca attaatgata aataggaggt gcagaccatg ttgttatcta
     5821 tgaatctaca attatttgcc cacaaaaaag gtggcggttc tacatctaac ggccgtgact
     5881 cagaatcaaa acgtctaggt gctaaacgtg ctgatggaca aacagttaca ggtggatcaa
     5941 ttctttaccg tcaacgcggt acaaaaatct atccaggtgt aaacgtgggt atcggtggag
     6001 acgacacttt atttgcaaaa gttgatggcg tagtacgttt cgaacgtaaa ggccgtaaca
     6061 aaaaacaagt gtctgtttat ccagtagctc aagaagctta attgaatctt atgattaaag
     6121 aggttgtgac aagacttttg tcacagcctt ttttgtttat aaaaataaaa gttgtagtgg
     6181 aggctacgaa gtttactttg tctttttaca cttaatattt ttttgccaat ttggaatcag
     6241 gatgttttga taactatcgt tttcaattga tggaagctat attgtttgct atcagtgaaa
     6301 taattatatg gtaaacagtg ttctttttct tgtttccatt ataaaaatcg tatcgggatt
     6361 tttcgttctt ttaaattgaa catttctatc tatccgcgtg ttatcaacaa aacaaaatca
     6421 ggtaaatagt tgacgaaaca gaaataaata catagtatta tgttttgaag cctaagtaca
     6481 atagtctata gaaaaggagc gataccattg gcaaaacgca ttgaccgaat ttatatgtat
     6541 gtcaaagaaa aaaccgctca tttaacaaag gcagaatatg atcaaggagt aacaacacag
     6601 gaaattgctg aagtgttagg gattcagcga acaaatagca gtaaagatct gaatcagcta
     6661 gtgcgcgaag gaaaactgat aaagacagac ggacgaccag tacgttacat atatcaaaca
     6721 ctcgttacgc acgtaaagcc agttacaaaa catgtagtca gttacaaaga aacgccggtc
     6781 tctgaagaaa aaaatacact ccaaatagat actaaggata tctttgcaaa aatcattgga
     6841 gctaacggca gcatgaaaaa ttcagtggaa caggcaaaag ctgcgatttt gtatccgcca
     6901 agaggattaa attgtttgat tacaggacct accggatcag gaaagactta ttttgcacac
     6961 gcgatgtatc attttgcaaa agcgcatcat gtaatagatg aggaaacgga actgattgtt
     7021 ttcaattgtg ctgattatgc caataaccct gagcttttga tgagtcattt atttgggtac
     7081 gcaaaaggtg cttttacagg cgcagatgaa gaaaaaatgg ggattatcga tcaagcggat
     7141 ggcggtatgc tgtttttgga tgagattcac cggttgccgc ctgaaggtca agaaatgatc
     7201 ttttacttta tggatcatgg aacttacagt cgtcttgggg aaacaacgaa atcccatgaa
     7261 gcaaatgtac ggatcgtagg tgcgaccaca gaagacccag gttcttctct attagaaact
     7321 tttgttcggc gtatcccaat caatatcaaa cttccggctt ttgaaaaacg tcctgcaaat
     7381 gagaaagtcg atttagtaaa aatcatgatt gcccacgaag caaaccgcac gcagcgaaag
     7441 atttctttga cagaagatgt agcaaaagca ttgatcggca gtgtgaccta tggaaatata
     7501 ggacaattga agtcaaatat ccagttagta tgtgcacgag gatttctaaa tcatatgcaa
     7561 tcacccgaaa tctcgatcac aatcgatgat ttgacagaag ggattcgtag cggattgatt
     7621 caattagcaa gcaaccgcag tgcaatggca gagctttcta aaatattgga gccaaagata
     7681 actgtagcac caaatgatac gatcatgaaa atccaatcgg actcctatga gttaccttat
     7741 aatctatatg atatcatcgg agataaagca gctttactga agtcggatgg tttggatcaa
     7801 gaagcaatca atcatttcat ttctacagat atcaacatcc atctgaagtc tttctataaa
     7861 gaccatggtt tttcttttaa tgcagacagc aaattagcag aatttgtaga tccgaaaatc
     7921 atagaagtga ccaatcagat ttatgtaatg gtcaaaagat ctttaccata tgagtttcag
     7981 caaaacttta tttatgctat gagcttgcat atcagttctt ttttgaaaaa aatcaactta
     8041 ggagaagaac ggcatacgaa tgataacatc cgtgagatgg cttttgattt tccagatgaa
     8101 tatgctgttg cgaaagaagt gcgtagttat atcgaaacgt attttcaagt ggagattcca
     8161 gaaagtgaag actattactt gaccgttcta ctcgtctcgt tacgggcaaa tcaagcaagc
     8221 ggcagaatcg gtgtagtcgt tgcagctcac ggaaacagca cagcaagcag tatggtccaa
     8281 gttgtccaac agttgttaga tgcagagaac gtacgagcag tagacatgcc tttggatatg
     8341 gatccgaaaa cagcattgga ccgaattgaa cgcaatgtac aagaagtaga tgaaggaagc
     8401 ggggtcatac tcttagtaga tatggggtcc cttgcgtcgt ttaattcgca aattcaaaga
     8461 gacactggaa ttccagtacg tactgttgat atggtaacaa cttctctagt tttggaaact
     8521 gtacgaaagg tctcagtatt agggacagat ctagatatgt tgcatgaatc attgaaaaat
     8581 tttcgaggtt acgcagaaat atcttctgta gaatctgttc aggaagcaaa acctattcat
     8641 aagaaaaaag ctgttttggc tatctgcgca tctggcgaag gtacagcaca aagaatcaaa
     8701 gaattgatcg aacgagcggt aaacaagcgt caagaaacag aattagaagt tctagctttg
     8761 tcgattgtgg aagtgaaaga agaactgcca gttatccaaa aagaatatca gatcatagct
     8821 actactggga ttactgattt gaatatccaa gccccattta ttcctttaga acgttttatt
     8881 gatcaaaata tcgaagtcat tttggatcag ttgctgatgg aatcagaatt ggaggaaact
     8941 gaattcatct ccctagatga agagtcagct aaaaatacgt gtgttgagtt tatctctgat
     9001 aacttcatct ttattaatgg tagtaagtta atcgatccaa tgtggcaatt ttctacacaa
     9061 atctctcaga cgacgggaat cggcgatgaa gaatatggat tcaaaatcaa cctagtgatg
     9121 cacacagcag gaatgatcga acgtattatt cggaatgaac cattgactgt ggaagaaaac
     9181 gaattgacaa atacaacgaa tgatcctctt tatagccaat tggcagcctc agttgttctg
     9241 ttggaagatc agataaaagt aaaagtgccg atagaagaaa tgtattatct gctacgtcta
     9301 gtccataatc agttagataa aaaagaatac actgtgccat gaatacacaa aaacgataca
     9361 cttttatagt gtatcgtttt tgtgtattgg ttaagaatcc tttaaattca attagtgtat
     9421 cgtaaaaaag ttggcacgct ttttgcttat agtagtgtgt gctaggaggt ggttgttcac
     9481 acagaaatga taggggtttc tgtgaagtag tgaggaagaa ggagttttgc agatggatat
     9541 tcgattggca cgtatagatg atcgtttaat ccacgggcaa gtcgcaacag tttggtcgaa
     9601 gcaaacaggt gttgaacgta tcattgtgat cagcgatgta gtcgctcaag ataaattgag
     9661 aaagtttcta ctaaaagaag ctgcaccgcc ggggatcaca gcaaatgtaa taaccgtgca
     9721 gaaaatgatt caaatctatc atagtggatt attatcacga gcaaaagtga tgcttttatt
     9781 caccaatccc caagatgttg aagcggttgt ccgctgcggt gtacagttga agtcgttgaa
     9841 tatcggcggt atgagtttta ctgaaggcaa atcaatgatt accaattttg tttcagtaaa
     9901 tcaacaagat attgattcct ttcgttactt gaacagtcaa gaagtggagt tagagattcg
     9961 aaaagtacct gctgacagga aaatcctttt gatggaacta ctagcgaaaa tcaaaaaggt
    10021 gtagcaagaa tggttgttgg aaaaggtcaa ataattctgt tgtaatggtt agcaattatt
    10081 aatatttttg aatttgttac aacaaaagta aataggaggt ataaatatgg tagggattat
    10141 cctagcaagt catggacaat ttgctgaagg aatcttacaa tccggttcaa tgatctttgg
    10201 cgaacaagaa aacgtcaaag ccgtgatttt gaaaccaagt gaaggtccag atgacttgag
    10261 agccaaattg gaagaagcgg ttgcttcttt tgataatcaa gacgaagtgt tattcttagt
    10321 tgatttatgg ggcggaacac cgttcaatca atcaaacaca ttattcgaag agcacaaaga
    10381 taaatgggca atcgtcagcg gtttgaattt accaatgttg attgaagcct acgcatcacg
    10441 cttttcaatg gaatctgctc atgaaattgc agcacacatc attgaaacag caaaagacgg
    10501 tgtaaaagta aaaccggaag aattagaacc ggcagaagca ccgaaagcag cagttgaaga
    10561 cgcacaacct aaaggagcac ttccagaagg aactgtggtc ggagacggaa aaatcaaata
    10621 tgtattagca cgtgttgact cacgtctgtt acatggacaa gttgcgacag cttggacaaa
    10681 agcagtgcaa ccaaaccgta ttatcgttgt ttcagatgca gtatcaaagg atgatctgcg
    10741 taagagacta atcgaacaag ctgctcctcc aggtgtaaaa gcaaatgtta ttcctattag
    10801 caaaatgatc gaagtagcaa aagaccctcg ttttggaaat accaaagcat tgcttttatt
    10861 tgaaaatcct gaagacgtat tgacagctgt tgaaggtggc gtagacatca aagaattaaa
    10921 tgttgggtca atggcgcatt cggtcggtaa agtcgttgta agtaaagtat tgtctatggg
    10981 acaagaagac gttgaagcgt ttgagaagct tgaacaaaaa ggtgtgaaat tcgatgtacg
    11041 taaagtacct aatgattcac gcgataacat ggatgatatt ttgaaaaaag caaaagctga
    11101 attagcaaaa gcgtaataaa taatattaaa atttatagga ggcttatcat gtctattatt
    11161 tcaataattt tagtcgtatt agttgccttt ctagctggta tggaaggtat tcttgatgaa
    11221 tttcaatttc atcaaccact agtggcatgt acattgatcg gtttagttac cggtaacctc
    11281 gaagctggta tcgtacttgg cggtacgctt cagatgatcg ctttaggttg ggcaaatatc
    11341 ggtgccgctg tagcaccaga tgctgcatta gcatcagtag catcagcaat tattttagtt
    11401 ttaggtggac aaggtgttaa aggtgttcct tctgcgatcg cgattgccgt tcctttggct
    11461 gttgcagggt tgttcttaac aatgatcgta cgtacaatcg ctgttccaat cgttcatttg
    11521 atggatgcgg ctgctgaaga aggaaacatc cgtaaggttg aaatgtggca catcattgct
    11581 gtatgtttac aaggggttcg tatcgcggtc ccagcagcag cgttgctatt tatcccagca
    11641 caaactgtgc aatcattcct tgaatcaatg ccagcatggt taacagatgg tatggctatc
    11701 ggtgggggaa tggtcgtagc tgtaggttac gctttggtaa tcaacatgat ggctacaaaa
    11761 gaagtatggc cattcttcgt tattggtttc gttgtagctg caatttctca attaacattg
    11821 attgctctag gtgctttagg tgttgcatta gctcttattt acttgaacct ttctaaaatg
    11881 ggtggttcat caaataatgg aggcggaagc aactctggtg accctttagg cgacattttg
    11941 aatgactatt aatcttgaag gaggaaaata aaatggcaga agaaaaaatc aaattatcaa
    12001 aaaaagatcg tttagctgtt gcgtggcgct ctaccttcat tcaaggttca tggaactacg
    12061 aacgtatgca aaacggtggc tgggcatttt ctatgattcc agcaatcaaa aaattataca
    12121 aaacaaaaga agaacgttct gcagcattaa aacgtcactt ggaattcttt aatacacacc
    12181 catacattgc ttctccaatt ttaggggtta cattggctct ggaagaagaa cgtgcgaatg
    12241 gcgcgcctgt tgatgatgta gcgattcaag gggttaaagt aggtatgatg ggtcctttag
    12301 ctggtgttgg tgacccagtg ttctggttta cagtacgtcc aatgctaggt gcactaggtg
    12361 cttcattagc tatgggagga aatatccttg gaccaatcat cttcttctta ggttggaaca
    12421 ttattcgttg ggcattcatg tggtatacac aagaatttgg ctacaaagct ggttctaaaa
    12481 ttactgatga cctttctggc ggattgttac aagacgtaac aaaaggtgct tcaattttag
    12541 ggatgttcgt attagctgcc cttgtacaaa gatgggtatc aatcaaattc ttaccagttg
    12601 tatcaactgt aaaattagat aaaggtgctt acatcgaatg ggataaattg ccttcaggtg
    12661 gtgaaggaat caagagtgca tttgaacaag ttaataatgg cttagccctt tctcctgaaa
    12721 aggtaacaac attacaagac aacttagacc aattgattcc tggtttagct gcattaggat
    12781 taacattgtt atgtatgtgg ttgcttaaga aaaaggtttc tccaatcgtt atcatccttg
    12841 gtttattcgt agtcggtgtt gttggacacg tcatcggact tttataatcc ataaaaatat
    12901 agctcgggcg ttgtcccgag ctttttttat atagtatact gttcataaac aaatatctgg
    12961 agggagaaaa tggttcaatc aatcaataca aaagtagact tggtaattga tgctacttcg
    13021 tttacgggtc tgacagatta cgggcaaatc atgataggta ataatggttt tgagttttac
    13081 catgcgcgag atagacgcaa atatatccaa attccatggg aagaagtgga ttatgtacta
    13141 gcatcagtca tgctaaaggg aaaatggatt cctcgatatg ccattcaaac gaaaaaaaat
    13201 ggtacataca cattttcttc caaagaacct aaaaaagtgc ttcgtgcgat cagagaatat
    13261 gtagatgaag atagaatggt acaatcattg agtttctttg atgtagtgaa acgtggtatt
    13321 cgtagtatgt ttaaacgcaa gtaaaaaata aagaaaactt ctaagaggag gttttcttta
    13381 tttttttact ttgcagaaga aaatatgaaa tagcaaaacc aattatttgt cccctttaaa
    13441 tcccatatgc taaaattgat tagcaaagaa ggaggttata ttatgagttg gttatggaca
    13501 ttgattgttg gagccgtgat cggagcaatt gcaggtgcga tcaccagtaa aggaaattcg
    13561 atgggctgtg taacgaatat cattgctgga ctagtcggtt caagtattgg acaagcgatt
    13621 ttcggcgaat ggggaccaaa agctgcaggt atggcactta ttccatctat tttaggcgca
    13681 gtgattttgg tagcagttgt ctcatttttc tttggaaaac gatcataagt ttttacaaaa
    13741 tagtaaacta aaaggagttg cagcgagact gtgactcctt tttggcttta tttatttaaa
    13801 ataaaaagaa gttttccgga aatttttatt taactgtcgt gtacgaagaa aagtttgcta
    13861 taatggaaaa aagcgtgcaa agaaagaggg agtttcatta tgatgctacg tgtagaaaaa
    13921 ttgcgcaaaa aaatgcaaga agaaaatttg gattcatttt tggttaccag tccgtacaat
    13981 cttcgttact taacgaactt tacaggtacg acaggattag ctgttattac tttggaaaaa
    14041 gcatttttta ttactgattt tcgttatacc gagcaggcgg cagcgcaggc tcaagggttt
    14101 gaaattatta aaaatgtcgg acctattttt gatgaggtag caaacttagt acgcaaagaa
    14161 gaactgcact cattagcttt tgaggaaaca acagtctcat ttttagaata ttcggtttta
    14221 gaagaaatca tcgatgcgga attagtacct gtttcacaga tgatcgaaga actcagagaa
    14281 gtgaaagatg aagaagaaat cgctattatc gaaaaagcat gtcatattgc ggatatggca
    14341 tatgatcaca tcctgaaaat gatccaaccg ggcatgactg agattgaagt cgcaaatcaa
    14401 ctagactttt atatgcgttc tcttggcgct tcaggtgttt cttttgatac gatcgttgct
    14461 agcggattgc gttcggctat gccgcatggt gtagcaagca aaaaaatcat cgaacaaggt
    14521 gacttgatca cattggactt tggttgctat tacgaagggt acgtttccga tatgacacgt
    14581 acattcgcta ttggtgatcc tggggaaaaa ttaaaagaaa tttatcaaat agtcttagat
    14641 gctcaattag cagttattga tgctgcaaaa ccaggaatga ctggtgtcca attagatgca
    14701 gttgctagag attatatttc aaaacatggt tacggggaag catttggaca ttctacagga
    14761 catgggatcg gtttagagat ccacgaagga ccaaacgttt cttctcgtgc agaaaagcaa
    14821 tttgtaccag gaaatgtgat cactgatgaa ccagggatct acttaccagg aatcggtgga
    14881 gtacgtattg aggatgactt gttgatcaca gaagatggaa atcgtgtgtt gactcgttca
    14941 ccaaaagaat tgatcatctt atagtttcat caatagaaga agtaagcgta aaaatcagtg
    15001 ttcacagact ttgttataga aaatcactcg atttaatgat acactataga agaactttta
    15061 agctgtaaga gataataaag ttgggtgttt tctccaattc atagcagttt gcagctgatc
    15121 ggcggcagtt ttcttaccac gtgatcacta tgccgcatca tagagaattc ggatgtatct
    15181 cgtgcttagg caaagggagg aataaataaa tggcagatga aaaaaatttg attttaaacg
    15241 caaaccaaga tttaggagag atcgtgatcg ctcctgaagt catcgaagta attatcggga
    15301 ttgcagcttc taaagtagaa ggcgtatacg gaatgcgcgg aacttttgcc agcaatgtca
    15361 ctgaattatt aggacgtgca gctcacggaa aaggtgttta cttagcaaac gaggaagatg
    15421 gcttgaaagt agatctttac tgttatctag aatatggtgt ttcagttcct aaagtagcaa
    15481 tggaaatgca ggaacgggtc agccagcaag tccttttcat gacggatatc gatttatctg
    15541 aagtcaatat ccatgtagta gctgttgttc ctgaaaaatt agaacaacca acaatcgaag
    15601 aactttttga agacgaagag gaagagaatg aataaagaat tatcaagaca cgagattcgg
    15661 gaaatggcat tgcaggcttt atttccatta gacttcaatg cagacctaac aaaagaagat
    15721 gcgattttca acgcaatcga attagaccac cgcgacatga tcaacgaaga tgaatcagag
    15781 tttgttcctg tttatcttga tacgctagtt ggcggtgtct gtgcaaaaaa agatgaattg
    15841 gataaagtga ttgaaaaaca tttaaaaaac aattggcaca tcaatcggat ctcaaaaatg
    15901 gatttggtga tcttgcgtat cgcgattttt gaaatgactt atgtgacaga tgtaccagcg
    15961 gctgttgctt taaatgaagc aatcgagttg gcaaaaacat ttagtgatga ccgttcacgt
    16021 aaattcgtca acggtgtttt atccaatgta ttgaaagaat tagaagctgg ggcgtaagtc
    16081 ctagcttttt tctatgaatc atcataaacc tgttataaat cgggaaaatt ctatggtaga
    16141 atgaaaacac aaaaaatatc tgggagtggt tagatggcag aattgattaa cggaaaagaa
    16201 ttagctgaaa aaatgcaggc agagattgct gaaaaaatcc aaaaattgaa agataatggt
    16261 atccatcccg gattagtcgt tttattggta ggggaaaatc cagccagcca aatctatgta
    16321 agaaataaag aacgtgtagc aaaagaaatc ggaatccatt cattggtaga gcgttatcct
    16381 gagacgattt ctgaagacga actacttgca gaaattgaaa aatacaatca agatcctagt
    16441 tttcatggta tattggtcca attaccattg ccaaagcata tagatgaaga aaagatcctg
    16501 ttagctatcc gccctgaaaa agacgtagac ggttttcatc cgatgaattt aggcagactc
    16561 cttgcgggta aaccggacaa gattccttgt actccatacg gcatcatgaa aatgtttgaa
    16621 gcttattcta tcgatccggc gggtaaacga gcagtagtta tcggacgaag caatatcgtc
    16681 ggtaaaccga tggctcagct actcttgatg gcagatgcaa ctgttactgt tgctcattct
    16741 aaaaccgaaa atctggctga actggcacaa gaagcagata ttttagtcgt agcaatagga
    16801 cgtggacatt ttgtcacaaa agaattcgta aaaccaggtg ctgtagtgat agatgtaggg
    16861 atgaatcgtg atgctaacgg taagctgatc ggtgatgtga aatttgatga agtggagcct
    16921 attgcaggct ggatcactcc tgtgccaaag ggtgtagggc caatgactat cacgatgctg
    16981 atgtatcaaa ccgtaaaatc tgccgaagct tttggagcag gtgaatagat ggcacaagaa
    17041 tatttaactg tcactacatt aacgaagtat ttgaaaagaa aatttgatgc cgatccttat
    17101 ttagaacgcg tatatttaac aggcgaaata tcgaatttcc gtttacgtgc caatgcccat
    17161 caatatttca gcttaaaaga tgaccatgca aaaatatctg ctattatgtt caaaggagca
    17221 ttccaaaaat tacgattcca gccaaaagaa ggaatgaaag tccttgtcgt tgggcgtatt
    17281 tcattatatg aagcgggagg ttcttatcaa atctatgtag agcacatgga gcctgatgga
    17341 ataggtgctt tatatcaaga attggaagaa cgaaaagaaa agctgatgaa ggaaggcctt
    17401 tttcaagggc ctaaaaaaat gctgccacgt ttcccaaagc gaatcgcggt ccttaccagt
    17461 ccaagcggag cggttatccg cgatatcatc acgacggtga aaagaagata tccaattgtc
    17521 caattggttt tgttcccaac agttgtacaa ggaaaccaag cagcggacaa tgttgtcagg
    17581 aatatccaga gagtagaaga gatgggcaat ttcgatacaa tgatcatcgg tcgtgggggt
    17641 ggttcgattg aggatttatg gccgtttaat gaagagcggg ttgctcgggc gatttatcaa
    17701 gctaatacgc cggtgatttc atctgtagga catgaaacag ataccacgat cgctgattta
    17761 gtagcagatg ttcgggctgc cactccaaca gcagctgcag aattagctgt tcctgttttg
    17821 tcagaagagt tgatgcgcat tcaagaacgg caagctagat tgcagcaggc gtttgtacgc
    17881 cagatccagc gcaaacaaga acggttcgag cgtgctcgac gttcctatgt atttcggcag
    17941 cctgaaagat tgtatgaagg tcagaccatc aaattagacc agttgaaaca gcgattatat
    18001 caagctacac agcaaattta tcatgcgaaa gaaaaacaaa cgatcgcatt aagccaccaa
    18061 ttggaacaag tggctccgct ttatcgagtt aaagcagctc gccaagaaac tgcttatcta
    18121 gaaaaacgct tagaagagaa aatccaacaa tatatgaaac aacagcagca gcgttttgct
    18181 caagctgttc aatctcttga tttgttgagt ccattgaaaa tcatgggaag aggctacagc
    18241 tatacgacgt taaatgatca agtagtaaaa agtgtcaccg agattcatca aggggatttg
    18301 ctgacgatcc attatcaaga tggaatcgtt aaaggacaag tacaagagat agacaaagga
    18361 gaataaaaat atggaaaatc caacttttga agagtcactg caagaattag aaaaaattgt
    18421 catgcagtta gaacaaggag acgttccatt agaatcagct ctagattcgt ttaaacgagg
    18481 aatggaatta agcaaacatt gccaagatac attagctaaa gcagaagaga ccttgacgaa
    18541 aatgatgaca gaatcaaatg aagaagttga ttttgacgga aacgaggaaa gctgagatga
    18601 gattaactga cttttcagct attcatctac ctgctgtaga aaaagaaatc ttgtcttttt
    18661 tagatgagca tacaacggat agaggactct atgatgcgat gagttattca gtgaaagcag
    18721 gcgggaaaag aatacgtccc ttattacttt taacggccgt tgcttccttt gatgagccta
    18781 ttgatgttcc cgtctatcaa gtagcagctg ctttagaaat ggtgcatacg tattccttga
    18841 tccacgatga tttgcctgcg atggacaatg atgatcttcg tagaggaaaa cctaccaatc
    18901 ataaagtatt cggcgaagca ttagctatat tggccggaga tggtttgctt acaggagcat
    18961 tccagctaat cagtatggca cacttaggta attctcctaa gcttctgctg cttcagcaat
    19021 tagctgtttg tgcgggatca caaggtatgg ttgctgggca agctgcagat atcgagggcg
    19081 aatcgaaaaa gctttcttta gaagaattag catttattca tgaaagaaag acagggcatt
    19141 tgattcgtta tgccttgctg gctggtggca tattagcgaa gcaacctgaa gaaatcttat
    19201 tgctacttca acgattagcc gaacatttag gtttagcttt tcagataaga gatgatctac
    19261 tcgatgtgat tggtacaacg aaaacattag ggaaaacagc tggtaaagat gaacgtatgg
    19321 aaaaaaatac ttacccgcgt ttattaggcc tagaaaagac acgtgaggcg ttggagattg
    19381 agctgttatc cgccaacaag atcatagaca aattagaaga ggacgttttt tcttttgatg
    19441 gcgggctgat gcgccagatg atcaagcaat ttgatgtgga gaaatgaggg aaagaatgga
    19501 aaaagaacgc gtagatgtat tagcggtcaa acaaggatta tttgaaacaa gagaacaagc
    19561 caaacgttca gtgatggctg gtttgattta caacgaaaaa aacgagcggt ttgataaacc
    19621 gggagaaaaa attccagtga gtagtgaatt aagagtcaaa ggtaaaaaac ttccttatgt
    19681 ttctcgaggg ggattaaaat tagaaaaagc actcaaagca tttgatctat ctgttgaagg
    19741 aaaaacattg ttagatattg gtgcatccac tggcggattt actgatgcag ctttgcaaaa
    19801 tggcgcaaaa atgagttatg ctttagacgt tggctacaat cagctagctt ggaaaataag
    19861 acaagatcct agagtcgtcg taatggaaag agtgaatttt cgttatgcaa aacccgaaga
    19921 ctttacctta ggaattccag aagttgctgt tatcgatgtt tcttttattt cactaaaact
    19981 gatgctgcct ccattacatg ctattttaaa agaagaggga gaagtgattg ctttaatcaa
    20041 accccaattc gaagcaggca gagaagctgt agggaaaaac ggaattgttc gtgaccctca
    20101 gacccatcaa aaagttttag aagacatttt gtcatttgcg gcacaaggtg gatatgatgt
    20161 gctggaatta agttattctc cgatcacggg gggagaagga aatatcgagt tcttggctca
    20221 cttgaggaaa gtacccgaaa gcggaacaat caattcagct attaatatgg cagaagtggt
    20281 ttcaaatgca cacgaacagt ttgaccataa ataaattgta actgtgaaaa tcaagtgaga
    20341 agtatgcgga ttcttcttta ttataccaag gaaataagct atcattgatt aagaagaata
    20401 tgctaaggag cgaagacgta atgagaaaaa aagatcggca tcgtttgatt actcgattgt
    20461 tgagtgagca agatatccga aagcaggaag aatttgttga aatcctgaaa agcaaaggaa
    20521 tatctgttac tcaagctacg atttccagag atataaagga actgaaactg atcaaggtac
    20581 cggcttcaga tggcggctac cgttatagca taccagctga aacaaacgaa gatgtaaata
    20641 ctaaattgga aaaactatta aaagacgctt tcgtggcagt tgaccaaatg gaaaaatttg
    20701 ttattttgaa aacattgccg ggaaatgctt cggcagcagc aaatttgatt gataaacgtt
    20761 acaagaaaga attattttcg attatcaatg atgacgataa tgttttgatg attacacgaa
    20821 ctgaagacca ggcagtttta ttgaagaaag acttcctgca ttacctttaa gttgaggagc
    20881 gaatgtgatg ctacaagaaa tcagtattac taactttgcg attattccgg aattgcggct
    20941 ttcttttcac gaaggaatga ccgcgctgac cggagagact ggtgcgggta aatccattat
    21001 tatcgatgct ttaggtctgt tagcaggagg aagaggttca agcgattata tacgtcaagg
    21061 agcagaaaaa tgtgtgcttg aagggttgtt tgaactacca aaacaagaag gattctctga
    21121 actgatggtt gaattaggga tcgaaacaga tgaggacaat ctgattgttc gacgggatat
    21181 gtccttaact ggaaaaaatg tttgtcgagt gaatggtcat attatcacat tagctaatct
    21241 gagaagaatc ggcagttatt tagtagatat ccaaggacaa aacgaacatc aggaactgct
    21301 ccagcctgaa tcacatcttg ctttattgga tcgttttgga gatgtagctt tccaacagaa
    21361 gaaaaagagt tatcagcaag aatatatctc ttatcgtgag ctggaaaaaa gggtacgaaa
    21421 agtgcagcaa aatgaaaaat cctatgttca gagaatagat atgctccatt tccagcaaga
    21481 agaaatagct gctgctgatt tgcaagtcgg agaagaagag aaattaaaag aagaaagaga
    21541 aaaacttagc aattatcaaa aaattgctga tggattagct gcaggttacg gagcactgac
    21601 gaataatgaa caaaacagtg tagatggtgt tggcttggcc gtttcagaac tgcaagggat
    21661 cgcccatcta gatgtggagt atgaagcaat ttatgaaaat atccaaagtg cttactattt
    21721 gctgcaagat gcaatcggcg atatgagtcg tcagattgat ttattggagt tagatgagag
    21781 tcgtttagaa gaagttacgc aacgtttaga attaatccga cagttgaaac gtaaatacgg
    21841 cgaatccatt gagtcaatat tggcttacta tgacgaaatc accgaagagc tagcttcttc
    21901 tgatttttca gaaggtcaat tggacaaaat gaaagaggaa ctagagcaaa aagagcttct
    21961 acttcagcaa caagccgcag atcttcatga agcgcgtaaa aaaatcgcaa aagaattgga
    22021 aaaatccatt ctgcatgaat tgaaaagtct gtatatggaa aacactgagt ttgaggtacg
    22081 tttcttaaaa gaagaaaata gacaattgaa tcatgatgga tttgaccaaa tcgaatttta
    22141 cattacgacc aatccaggag agccactgaa gcctttggtg aaagtcgctt ctggtggcga
    22201 actgtctcgg atgttgcttg ctttgaaaac tattttttct tctgagcaag gtgtgacaag
    22261 tattattttt gatgaagtgg atacaggtgt gagcggaaga gttgcacagg ccatcgcaga
    22321 taaaatttct caaatatcga aatactctca agttttgtgc atcactcatc tgcctcaagt
    22381 tgctgcagtc gccgactatc aatattatat tgtgaaagca gtgattgatg gacgtacgca
    22441 aacttctgtt tcagagttga aaacaaaaga aagagaagaa gaaattgcac gtatgctggc
    22501 tggaagtgag attacaaaac tcacactcga acatgcaaaa gaactattga aactcgcaaa
    22561 aaggacctga gccacctcgc agtggttcag gtccttttca gcagctgata gctatatttt
    22621 atttttacat gacactcatt acagcagtca atacaacaga tccaatcgtt aaaatcagca
    22681 ttgtccaaat gacaaatttt gttactttag caaaagtact tgtttgtttt ttttcacgca
    22741 ttgttttcaa cctcgtcatt aattagttga ttcaagtgta caatcttttt tccatttcca
    22801 caagagggct tttttataaa aacttccctt tttttaaata ataggtagtt acgatacaaa
    22861 taaataatgt taatagaact agccatataa aggcatcatc cctttcagca ataggtaact
    22921 taatgttcat tccatagata ctgccgacga ttgtcggtat agttaaaata atcgttaaag
    22981 aagttaaaat tttcataata ttattcagat tattcgatac gattgctgaa aaagtctgat
    23041 tcatttgttc tactagtttt aattgaatgc gagaagtagt cattgcctgc tctgtttcca
    23101 ccaatacatc acgtaaatga tttttcaaag catgattttc ttggaaaagt ttattttgcg
    23161 ctagttcttt caatgcatct aaattagcag aagtcgcttc tctgaaataa acgaggcttt
    23221 tttggatatc catgatttga taaagttgtt tgttttcagt ggatacttga agtttggctt
    23281 ccaaagtatc gcattgagat tgaagcgtag ctaaataact gttgtaagag agtgtgacct
    23341 gccaaatgaa ttgaaagaag atattgagat taggcgaaat atcacttttt ggaaaggtct
    23401 ggctaaagac tttctttaaa aacagtggtt catgattcgt aattgtgata agcttctttt
    23461 tgggcgtcaa aataatagag agcgggtatg tatccacttg aaaataaccg ctaggacttg
    23521 ttttagcaaa aggatattgt aacaataata acgctggctt tgtcaacttt gattgattga
    23581 attcttctgt acgggaattt tctgcatcgt ccaatatgga agtgatgtaa tctgacggaa
    23641 tttcaaattg atgtgtcagc tgatgaatct cttcttgatt aggacgttct acacaatacc
    23701 agatcgtttg gtcagtttcc tttccggtat tacgcagttt ctcattatct aatgtaaaat
    23761 atttgatcat gattttcctc ctgttgcctg tttcttttat tataacggat agggaattgg
    23821 aatacatgga atgtgtttgt aagatataga atataactgc ataaatttaa ataaaatgaa
    23881 acagttgtgt aaagtatata cagtatactt gaagcaacga taaaaaagga gtttacgttc
    23941 atgggcacat tcacaccact tatcttgttt tggtatattt acccggtaat cgttttgttt
    24001 ggttgccaat ttcttgtaaa attattttcg ttaaatcgtc gttttaaaat aaaagcccct
    24061 gatttggcga ttcctttttt gtggggcggt atgcatgcat tgtctagaaa tacagggaca
    24121 atttctatct taccgttttt ctttatttct gttttgctaa tgggaatttg tattgctgtt
    24181 ttccaagcat attattatga agaaattatt tatccgcgtt atttcaagat gacttggcgt
    24241 ttggtttttc tgttgacaat cgtcttgtac gctgtcttga tcattgtgaa catactttct
    24301 tacctatgaa aaaaatagaa aagctgtaaa aagtctttta aaaggctttt tgcagcttga
    24361 tttttaaaaa aatgtttatg aataaaaaaa gttgttcccg gatttcccag aaaaggtggt
    24421 agaaagtggg ggattgtggt agactaattt tagttagtgg aggaatgggg ggctttcaat
    24481 gttgatgggt gaattccaac ataatattga tgcaaaagga cgtttaatcg tgccctcaaa
    24541 acttcgtgaa gaacttggcg aaaagtttgt tctgacacgc ggattggatg gctgtctttt
    24601 cggctatccg atgagcgaat gggaaaatct ggaagctaaa ctgaacgaaa tgccgttggc
    24661 taaaaaagac gcacgtactt ttgtgcgatt cttctattcg gctgccactg aatgcgaact
    24721 tgataaacaa ggacgaatca atatacccag cacgttaaga aattatgcag ctttgacaaa
    24781 aggttgcgta gtcatcggtg tatctaaccg aattgaaatt tgggatgaga cacgatggca
    24841 agatttttct gcagcagcag aagagaactt tgacgaaatt gctgaaagta tgattgattt
    24901 cggactataa gaataggaag aggctgacta atgactgaaa catttcaaca ctatacagtc
    24961 atgttgaaag aaacggtaga tggattgaac atcaaaccgg atggcgttta tgtagactgt
    25021 acactcggcg gtgccggaca tagtgaatat ttattaagcc aactaagttc taaagggcat
    25081 ctgtatgcgt ttgaccaaga tcaaaaagca atcgatcacg ccaagctgcg tttagcttct
    25141 tatgtcgaac aaggtatggt cacatttatc aaagcgaact tcagagaatt agaagaacgc
    25201 ttgagtgagc atgtagataa ggtagacggc attttgtatg atctaggggt ttcctctcct
    25261 cagctagatg aagcagaacg tggatttagt tatcatcaag atgcaccgtt ggatatgcgc
    25321 atggatcagt cagctccttt atccgcttat cacgtaatta atgaatattc ctaccatgaa
    25381 ttagtaaaga ttttcttccg ctatggcgag gagaaatttt ccaaacaaat tgctcgtgaa
    25441 atcgaacgag tacgaaaaac aaaaccaatc caaacaactg gtgagcttgt cgaaatcatt
    25501 aaacaagtca tcccagctcc cgcaagaaga aaaggcgggc atcctgcaaa aagaattttt
    25561 caagctgtgc ggattgcagt aaatgacgaa ctcggtgccg aagaggcctc tttagaacag
    25621 gcaatccggt tattgaaagt caatggaaga atcagcgtaa tcacattcca ttcattggaa
    25681 gacagaattg tcaaaagtat gtttaaagaa tatagtacgg tacaagatct accaccggga
    25741 cttcctgtca tacctgacga attccaacca gaactgaaag tcattactcg taaaccaatc
    25801 cttccttcag aggaagagct aacagaaaac aatcgatcac gcagtgcaaa gttacgtatt
    25861 gcagaaaaaa taagaatgaa agaggagtag aatgatggca gaattaaaga aaatgcaaga
    25921 ttacgaatat gatttacctg aattggtgga tcagccggaa caacaaatgc ctgattcttc
    25981 ttcgaatcaa gaaatcattc ttccacaatc accggcaaaa cgattaaagc agatttctgc
    26041 tttggaaaaa attgctgtgg caagcgtggc gattgctatt gttgctttat gtgttttaac
    26101 agttatgctg cgcacaaata tcagcggagc tgaaaaagaa atcacgtcaa tacaaacaga
    26161 aatcaatgat aaaaagcaag aaaaaacgag tttagaacaa gaaaaaaacg aactttctcg
    26221 tactgaacgg attaaacaaa tcgcagaaga aaaaggattg tctattaatg acgacaattt
    26281 aaggaaagtg aagtaaatga gtcttaaaaa taaaattcgg cggtttatgg aaaagaaaaa
    26341 tctaaatccg atgaacaatc gcaaaaaagt aggtatcatt ttatttgcta cgagtattgg
    26401 attgttcttt ttatttgccg tccgtttctc gtatatcgtt attggaggtc atgttgctgg
    26461 tacctcatta gctgaaaaaa caaaacagtt gtaccaagga agtgaagtag taaaagcaaa
    26521 aagaggaacg atttatgatc gtaacggtgt ggcgctcgca gaagatgcct cctcttattc
    26581 aattaaagcg atactctcaa aaacatatac ctctggggat aaaaaactgt atgttgaaga
    26641 aaagaatttt gataaaatag cagaaatcct gcataagaat ctttctatag acaaaaaaga
    26701 tgcactgaat attttagagg acggcgcaaa aaaagagctg tatcaagttg aatttggtag
    26761 ctatgggaaa aatatctccc aagaaaccaa gcaaaacatc gaagcggaca tgaaaaaaga
    26821 aggtgtcgct ggtctttatt ttgtcgacca tcaggctcgg atgtatccaa atggcgtctt
    26881 ttcttctcat tttattggat acgcagttcc agacaaagat gagaatggct tagttggtaa
    26941 actaggtttg gagtctgctt acaatgatat cttgagcggt aaagatggta agattattta
    27001 tcaaaaagat aattttcaaa atcctctgcc aggtacagtg gcagaagaag aaaaagctgt
    27061 cgacggacaa gatatctaca cgactttaga cagcagacta caaagttatt tagaaacact
    27121 gatggatcaa gtaaatgaag aatatcagcc agaagaattg acagcagtcc tgatgaaagc
    27181 aaaaaccgga gaaatcttgg caatgggaca acgacctact ttcaatcctg aaacaatgga
    27241 aggattgact ggaaaagatg ctatctggcg taatttcttg gtacaagata gttatgaacc
    27301 aggatcaacc atgaaagttt tcactactgc agctgctatc gaagaaggag aattcaacga
    27361 gaatgaaacc ttccaatctg gaaaaatcca agtagaagat gctacgatca atgaccatga
    27421 ctttggtgaa aaaggtgtgc tgaccatgcg tcaagctctt tcatggtcaa gtaacgtcgg
    27481 gatggtcata ctggaacagc gattaggcgg acgatggtat aactatttac aaaaactggg
    27541 atttggacaa agtactcatt ctggattaga tgatgaagta aacggtgctt tacctacatt
    27601 aaatattgtc gaccgagcaa tgagtgctta tggacaagcg gtaggtgtga cgaatttcca
    27661 aatgatgaaa gctttcactt ctattgcgaa taacggtaca atgattcaac ctcgatatat
    27721 cagcaaagtg gtggatcccc aaactggaga agagcgaaca actcaaacag aagttctagg
    27781 gcaacctttt tcaaaagaaa caacagaaaa agtccgtgaa tatatgagag atgttgtcga
    27841 aagcgaaaac tacggtagtg cttatggtgt atatagtgta cctggataca atgtatcggc
    27901 aaaaaacgga acagcccaaa tcgcttctga tacaggggga tatcaaacag gagatacagc
    27961 ctacctgtat tcgattgtgg agatggttcc ttctgaagat ccagactatg tcttgtatct
    28021 aacaatgaaa caccctaaga catatgatcg aatggcattg gctaaaatcg caaatccatt
    28081 gatgaaacgg gcaatggatt ttaaagaaac tgaagaagat tcagatacag aaacaaaaac
    28141 agaaaaagta tccgtagccg attatcgtaa tcttgaagcg gacgttgcag cagctgatgc
    28201 tcaaaaaagt ggactgcaac ctgtagtgat cggtaatggt aaaaaagtac aaaaacaatc
    28261 tactgccaac ggtgatcagt tgatctctgg agaaaaactg atcctatata ctggtggtga
    28321 taagctgatg cctgacgtaa caggatggtc aaaagcagat atcatgaagc tggggaaaat
    28381 cctcggtatt gaagttagtt ttgatggaga tggttattgt gtcaaacaag aacttgctcc
    28441 atatgaaaaa atcactgaag acaaacttag ttttacttta gaagaataag aagagaaata
    28501 ggagagaaaa gagcatggaa tggacacaag cattgattcc cattgtcagc agttgtgcaa
    28561 tgacaattgc cgcaatgccg ctatttattg gttattttca aatgaaaaag caaggtcagg
    28621 cgattcgtga ggagggacca aagtggcaca atagcaaagc cggaactcct acaatgggcg
    28681 gcttagtgtt tctgatcggc tctattttga caggaatttg ggttggagct tggcaaaaac
    28741 agctaactcc tactcttttc atcttgcttt ttgtattagc gttatacgga gtaatcggct
    28801 ttcttgatga ttttataaaa atattcaaga aaagaaacat gggactgaac tcgaagcaga
    28861 aattgattgg acagattcta gggggaatca tcttttatct tgtttaccgt tctgaaggtt
    28921 atccaggtgt attgaatttc ttcggactag atctaccttt aggaatcatt tatggtattt
    28981 tcgctctctt ctggcttgtt ggattttcaa atgcagtaaa tctgacagat ggcatcgatg
    29041 gattagttgc tggcttagga agtatctctt ttgcagctta cggtctaatt gcttggcatc
    29101 agcatcagta tgatgtatta atcatttgct taagtgtttt aggaggttta ctgggtttct
    29161 tcgtctacaa cagaaaacct gccaagattt ttatgggaga tgtcggttca ttagcgttgg
    29221 gcggactttt agcggcaatt tctataatgc taaaccaaga atggacattg cttttgattg
    29281 gtttgatcta tgttatggaa acagcaagtg tgatgcttca agttacttcc tttaagctta
    29341 caggaaaacg aatttttaaa atgtctccaa ttcatcatca ctttgaaatg tgcggatggt
    29401 cggagtggaa gattgataca gttttttggt tgatcagcat tgtgacttcg ttgatcacat
    29461 tatggatcgt ttggtaggag atgacgggaa atgaaaaaaa tatcaacata tgaaaataag
    29521 aaagtgcttg tcttaggact cgcaaaaagc ggagtaagtg cggccaaatt attacatgaa
    29581 ttgggcgcac ttgtcaccgt taatgatgga aaaccttttg acgaaaatcc ggaagcacaa
    29641 gagctgcttt ctttagggat aaaagtaata acaggtagtc atccaatcga attgttggat
    29701 gaagaatttt cattgatggt caaaaatcca gggattccct acagtcatcc tttagtagca
    29761 aaagcccaag aaatgggtat tccggtaatt acggaagttg agctagctta cgaagtagcg
    29821 gaatgcccaa ttattgggat tacaggaacg aacggaaaaa caacgacaac aacgatgaca
    29881 ggactactac tgaatgcagg agcagatcaa ggaattgcac gtttagcggg taatattggg
    29941 tatccagcaa gtggtgtagc gcaagaagca aaatcagaag ataaaattgt gatggaattg
    30001 tctagcttcc aactcatggg aatcacagat ttccgccctc atatagcggt gattaccaat
    30061 atctatgaag cacatattga ttatcatggt acaagaaaag aatatgtcaa agctaaatgg
    30121 aaccttcaaa aaaacatgac agaaaaagat tatctgatcc ttaactggaa tcagtcagaa
    30181 ctacaagaat tagcgcaaag aacaaaagca cgcgtactgc ctttctcgac aaaagaagtg
    30241 ttggaagacg gtgtgtatgc tgacgattac tcaatatact ataaaaaaga aaaaataatg
    30301 gaaatatctg aacttggcgt accaggtaag cataatgtag aaaatgcact agctgctatt
    30361 tctgtagcaa aattgtatgg tatatcaaat gaagctatac gagaaacgtt gcattttttc
    30421 catggcgtac cacatcgtac gcaatatgta ggagaaatcc aaggcagaaa attttataat
    30481 gattcaaaag caaccaatat tttagcgact aaaatggctc taagtggatt tgaaacgtct
    30541 aaggtcgtgt tattggctgg cggattagac agaggaaata catttgatga attaattcct
    30601 tcattaaaag gaatcaaagc aatggtcgta tttggccaaa caaaagaaaa gttgatggat
    30661 gctggaaaaa aagcaggcat cgagacaata gtaacagccg attctgtaga acaagcagtt
    30721 cctttagcat tagaaaacag tacagatggt gatgtagttt tattatcacc agcgaatgcc
    30781 agctgggatc aatacccaaa ttttgaaact agaggaaaca gattcatgga agctgtgaac
    30841 cgattaaaat agaaaaagta gaagcgagcg ataaaaaatg aaaattttgg ttacaggcgg
    30901 aggaacaggg ggacatattt atccagctct tgcctttgtc aattatgtaa agactcaaga
    30961 accgaatgct gaattcatgt atgtgggagc aaaacgaggt ctagaaaaca aaatcgtccc
    31021 tgatacagga atgcctttcc ataccttgga gattcaagga tttaaacgaa aaatttccat
    31081 gcataacatc aagacggtcc gattgtttct taagagtatc cgtcaagcaa aaaaaatcct
    31141 cagtgatttt caaccagata tcgttatcgg tactggagga tatgtttccg gagcggtagt
    31201 gtacgctgca gccaaaatgg gtattccaac agttatccat gaacaaaaca gtgtaccagg
    31261 tgttaccaat aaatttttaa gccgatatgt ggatcggatc gctctttcat ttaaagatgc
    31321 ggcttccttt tttcctgaaa acaaagcagt tcttgtaggt aatcctcgag cacaagaagt
    31381 agcagatact aaaaaatcag atattttgaa aacatttgat ttggatccag aaaagaaaac
    31441 agtcttgatt tttggcggta gtcaaggagc acttaaaatc aatcaagcag tatcagtttt
    31501 tttaagtgaa tatattcctt cttcttacca agttttgtat gcttcaggag atagatatta
    31561 tgaagagatc ctaaataaaa taaatcctga aatacaaaat attagtgtcc agccttatat
    31621 caaaaatatg gcagaggtca tggcttccag tgatctgctg gtggggcgtg ctggtgcaac
    31681 ttcgatcgca gaattcacag ctctggggtt accggcagtg ttggttccca gcccatatgt
    31741 tacgaatgat catcagacta aaaatgcaat gagtcttgtt cacgcaggag cagcaaaaat
    31801 gattgcagat aatgaactaa caggtgaatc actaagtcag acagtcaacg aaatcatggg
    31861 tgatgaagaa ttgcaaaagc aaatgtgccg agcttctaaa gaacaaggaa tccctgatgc
    31921 ttcaaaacgt ctttatgact tagtaaaaca aataatcaaa aaataaaggc ggtggtctta
    31981 gtgagtaaga aaaaagaacc aaaaaaattg tctcatccgt cttctgatga aaacaatttg
    32041 actccttggc aaaaggctaa ccgaaaatat ctggcagaac aagagatgaa aaaccaagag
    32101 ccaaaaaaag aagacataac attagataca cccctttcag attctgaaga agaaaaaacg
    32161 gttcaagagg aacagcaaga agaaagccag tccgagaaaa aaatcgaatt ttttgaagag
    32221 atcaagcaaa agaaaaacgg tggaccatat aacggttctt ttttgaaccg gctgcccaat
    32281 ttaaaaagtc aacggcacaa agtactattt cgtcggttag ctttgatcat cactgtattg
    32341 ggtataccgc tgattttttt gatctattat gtttctcctt atagcaaatt acaagcagtt
    32401 gcagtatcag gcaataagac agtcaacagc caagaaatca tctctgatac aaaattgtca
    32461 ttaggagaaa atgtttgggg acagtatttt catcgatcta cttatatcga tcgccttaaa
    32521 aaagcacagc caagaatcga aacagcaaat atacatttca aagggatgaa tgaattcgat
    32581 ttggatgtaa cagaatataa agagattgct ttgatcgcaa aaaacaatca atactaccca
    32641 gtgattgaaa atggaacagt attagatgaa aaagtagcaa atcctacaaa aaatctccct
    32701 atcttggaag agttcaaaga ctctgcaaaa atcaaagaat taacaaagca atacaatcag
    32761 ttatcatcag aattacaaaa agcaatttct gaaatcaagt acacgccaag agcaagcaat
    32821 aaaaatctga tccaattgaa tatgaatgac ggcaatcaag ttattgtaaa tatcaataat
    32881 cttgcgaacc aaatgaaata ttattcgcaa gtagccaaag atatggatga aaaaggtgtg
    32941 atcgacatgg aagttggtat cttctcgcat ccttacggta gcactcaaga aacggaagaa
    33001 tcgggccaat cggaagaaac aactgaaagt gaagaaaatg cggatcaaac aaacgaatca
    33061 agtgaagagg cagaaacgca aaaagcacaa acacctggat cgtctagcac aaacggatca
    33121 tctgattcaa atgattcaag tgaaacaagt caaatagaag ataatccaag tacaactccg
    33181 tcaagtttaa atgaaaattg ataaaacaac tttaaaaagt aagaatgtac tttctaaaaa
    33241 ccagtaattt atggtagaat tggaagcagt gaatatatct attaataagt atattttaaa
    33301 acggacgcta gttgttcgct tgtatatgga atagtaagta ggagggaatc ccattcatgg
    33361 caaaaacagg aatgtatgta ggccttgata ttggaacgac atctgttaaa gttgtcgtgg
    33421 ctgaatatat cgacagccaa atgaatatta ttggagtagg aaacgcaaaa tcagaaggga
    33481 ttaaccgagg cattatcgtt gatatcgata aaacggtcca agcgatacaa cgagcagtac
    33541 gacaagcaga agaaaaagca ggtatccaga tcaaaggcgt aagtgtcggt ttgccagcaa
    33601 acatgcttga agtagaaaat tgccagggaa tgattgcagt taacggagat tcaaaggaaa
    33661 tcaccgatga agatgtcaga aatgtggctt cagctgccct tgttcgttca atacctcctg
    33721 aacgtcaaat cgtgtcaata ttgccacaag attttactgt cgatgggttc gagggaatca
    33781 aagatcctcg tggaatgatc ggcgtaagat tagaaatgta cggtctgttg tttacaggac
    33841 ctaaaacgat catccataac atacgtaaat gcgtggaaaa tgccggatta atcgtcaacg
    33901 aaatggtgat tactccttta gcgctgactg aatcaattct ttctgacgga gaaaaagatt
    33961 ttggtacgat cgtcattgat atgggtggcg gccaaacaac aacggctgtt atgcatgata
    34021 agcaattgaa gtttaccaat cttgaccaag aaggtggcga atttgtcact aaagatatct
    34081 ctattgtatt aaatacgtca tttaacaatg cagaagcgtt gaaaataaac tacggggatg
    34141 catacccaga acggacatca ccagatgaag aatttccagt agatgtgatt ggtcagtcag
    34201 aaccagtgaa agtcgatgaa cgctacttgt cagaaattat ttcagctcga atggaacaga
    34261 ttttcaacaa agcaaaagat gcattggacc aaatcgaagc attagagttg ccaggtggcg
    34321 tcgtattgac aggcggagct gctagtcttc ctggtgttgt ggacttggca caagaaatct
    34381 tcggcgtaaa tgtaaaattg tatgttccaa atcacatggg gctgagaaac ccggtattta
    34441 caaatgtaat aagtatcgtg gattattcag caaacttgag tgaagtgtat caattggcaa
    34501 aaattgctgt tacgggtgaa acctcagcag ctcgtcaaat ggtagttgaa caagaaacaa
    34561 caaacacata tgagagctat gaagcacctg aagaaacaat ctacgatgag ccggaaccaa
    34621 aagagtccgg agaaaatgta aaaaataaaa tcaagggttt ctttacaaat atttttgatt
    34681 aattcatcct gggaggaata agatatggaa ttctcaattg ataataatat caatgacggc
    34741 gcagtaatca aagtcatcgg agtcggtggt ggcggtggaa atgctgtaaa ccgaatgatt
    34801 gaagaaaacg ttaaaggtgt tgaattcatt acagccaaca cagacgtgca agcattaaaa
    34861 aattcaaaag ctgaaacagt tatccaatta ggccccaaat atactcgtgg tttaggtgct
    34921 ggttctcagc cagaagttgg acaaaaagcg gcagaagaaa gtgaacaatc cttacgcgaa
    34981 gctttagacg gtgcagatat gattttcatc actgcaggaa tgggtggagg aaccggtaca
    35041 ggtgctgcac caatcgttgc aggtatcgcg aaagaattgg gcgcattgac tgttggtgtc
    35101 gtgacacgtc cattcacttt tgaaggaccg aaacgtggcc gttttgctgc agaaggtatc
    35161 gctcgtttga aagaaaatgt ggatacatta ttaattatct caaataaccg tttattagaa
    35221 gttgtagata aaaagacacc gatgcttgaa gctttccgtg aagcagataa tgttttacga
    35281 caaggtgtac aaggtatctc tgatttgatc acagcgccag gttacgttaa ccttgacttt
    35341 gctgacgtga aaacagtgat ggaaaaccaa ggtacagcat tgatggggat cggtgtggct
    35401 agtggagaag atcgcgtagt agaagcaacg aaaaaagcaa tctcctctcc attgcttgaa
    35461 acatctattg atggagctga acaagtactt cttaacatca caggcggttt ggatatgaca
    35521 ttgttcgaag cacaagatgc ttcagatatc gtagcaaatg cagcaactgg cgatgtaaat
    35581 atcattctag gtacatctat caatgaagaa atgggcgatg aaatccgtgt gacggtcatc
    35641 gcaacaggta tcgatgaatc aaaaaaggaa cgcaagtcta gccgaccagc tagacaagca
    35701 caaatgcaat cacctgctca aaagactgta ttagatatgg atcaagctaa accaacttct
    35761 tcagaagaag aaaacagttt tggcgattgg gatatcagac gtgaacaaaa tgttcgtcct
    35821 agagttgatg attccaattt tgacaatatc gaaaaaaaag aatttgatac attcaaccgc
    35881 gaagaaacaa aatctcatgg cgatgatgaa ttaaatacgc caccgttttt ccgtcgtaaa
    35941 aaataaagga gaggaagagc acatgattgc tgacaacttg cagaaaatca agcaagaaat
    36001 tcaggattcg tgtgctcttg ttcatcgtga tccgaaagaa gttacattag tagctgtaac
    36061 aaaatctgtt gaatccgctc aagctgaaga attggttaga gctggcgtta tgaattgtgc
    36121 agaaaaccga gtagataaat tattagaaaa gaaacaagat ttatttgatt ttcctgaaat
    36181 aaagtggcat ttaattggta atttacagcg cagaaaggta aaattgattg taaatgaaat
    36241 tgattacttt catgcgttgg acagtttaag attagcagaa gaaatccaga agcggttaga
    36301 gaaagaatta tcctgtttta ttgaagtaaa tgtttctggt gaggaatcaa aacatggaat
    36361 ttcaccagat gagcttttac cgtttgtgga atctttagct gcctgcacaa aaatcaaggt
    36421 tgttgggttg atgactatgg cgcctaaaga agcttctgat gagcaaatcc ataaagtgtt
    36481 tggtacgctg aaagaattgc gtgatcttgt tcaagcaaaa ggttatgccc atgcaccatg
    36541 tagtgaatta agtatgggga tgagtcaaga ctttcaaatt gcgattgaag aaggtgcaac
    36601 atttatccgt gtaggaacag cgctattcaa agacgaataa aggaggaaca aaaatgccgc
    36661 ttttaaacag aggagcaatt gctaattttt tcggattagc tgatgaggaa gagtacgaat
    36721 accaagatta tcctgaaaca acaaaaaagg ctgtacagcc aactaaaaaa aatacaacac
    36781 agaatcaatc aactcattct gtatctgctg cgaatactca tgaaaaacaa aaaacggcga
    36841 cttcacgtcc tgtaacgcat gaaagtattc agccggctga aaagaaaaaa gtaattgaac
    36901 tacatcaatc acctacaaaa actgtagcga aagaaagaac agcttcaaga acctctacac
    36961 aacctaaagc aaatcttgct ggaaaaatca ctgtaatgga accaagagct tattctgaag
    37021 ctatggcgat tgctaaacga atcattgctg gagaagcaac cttagtgaat tttcatttag
    37081 tagaagaaaa acaagcgaga agaatcgttg attttctaac aggaacagtt tatgcactag
    37141 atggagatat caaacgtgtt ggagatgaga tttttctttg tacaccgact gggatggaga
    37201 ttgacagttc aaccgctcaa tcttttgcag atgcgaattt gtttgatctg taagaggagg
    37261 aactacgatt tatactattg cactattact tcatttactt caacgggcag cctatttcta
    37321 tagcattatc ttgatggtat atgcattgct ctcttggttt ccaggcgggt atcaatcagg
    37381 gctaggacga ttattagcta agatctgcga accgtatatc agtttgttcg atcgtctgcc
    37441 tttgaggatt ggacccttgg atttcacaat tttaggggca atcctgatct tgaacttagc
    37501 cgtacaaggt ttagcacaga tcgttatatg gataactgtc catttagttt attgattgaa
    37561 gcaacaaaat ctttattctc agaatagata ggaggggaaa attttggatg caaatgtata
    37621 ccagcacttt cgggcagatg aacgtacatt tatcgattcg gtaggcgatt ggattgaaca
    37681 ggttcaagga caatatgcac cctatctgac cgaatttctt gacccaagac aatcctatat
    37741 tttagaaaca ctgattcgac aaagcagtga tttgcgtttc atgttttatg gcggatatga
    37801 acaggcagaa agaaaaagat gtttgatttt ccccgattat tacgaacctg tagaggaaga
    37861 ttttgaaaca gcattgtatg aaatccatta tcctagcaaa tttgccagcc taagtcatgg
    37921 gaaaatcctt ggaactttag tgggaacggg gatcaaacgc tcttactttg gcgatatcat
    37981 ctcggacggt gatcgctggc aagtatttat tgcaaatgag gtggatcatt ttgttgctgc
    38041 acaagtaaca aagattggaa aggttgctgt acgcttggaa ccaatcaaat acacagaaat
    38101 gattatgccg aaagatagct ggacacaaga aagaggaaca gttagttcca tgcgactaga
    38161 cagtgtgatc tctgagattt ataatatttc cagacagcgg tccaagcagc tgatcgaagc
    38221 tggtaaagta aaagtgaact ggacagaaaa tacaagacct gattttgtac ttgaactatt
    38281 agatattatt tcagtcagag gttatggcag agtccagatc caagaacttg aggggaagac
    38341 gaaaaaagaa aagtacaggg tactgttcgg tgtattacgt aaataaaata aaaaggtggt
    38401 ttactcatgg ctttaactcc attagatatc caaaataaga cattcccgac aaaaatgcgg
    38461 ggatataatc aagacgaagt agatgatttc ttagatttag ttgttcgtga ctatgaggaa
    38521 ttgactcaaa gaaatcgaga attagaaaaa gcagtcaaac attctgaaga aaaacttgag
    38581 tacttcaatg aattaaaaga tgctttgaac caatcaatca tcgtagctca agatacggct
    38641 gataaagtaa aaacaagtgc aagcaaggaa tccgaagtga tcgttacttc tgcacaaaac
    38701 aaagcagatg agttagttgc gaacgctgaa aaacgtgcac atcaattaac aactgatgca
    38761 gaagaaaaag caagaaaaat cttgacagat gcaacagaaa aagcaagaca gcttgcgaca
    38821 gaaactgaag atcttaagaa aaaaacacga gtattccatc aacgtatcag cttgatgctt
    38881 gagtctcaat tagaacaagt gaaaagtccg gaatgggatg aaattttaca accattctcc
    38941 agctacgtga ctgacagcca tgaagtgatc aaagaagttt tagcaaaaca gcttgacaat
    39001 gaaaatgata ctgatgtaaa ctcagacaca ggagtcatag aagcacctat gacggcattt
    39061 gatacacagg ctattgatat ctcgatcgtg cctggtgaaa atgaaaacga gtagaacaga
    39121 aaagcacttt gttattctta aagcgagccg atgagagtgg aagttcggta agacactgca
    39181 tggtgaaaga tcctctactt gagacctgct tttccgaaat tagagtaaga agcagcggct
    39241 gacctcgtta ttggtcacag agagtttgca ctagatagat gcaactaaat ttgggtggta
    39301 ccacggcatg ttcgtccctt gcggctgaac atgctttttt gtgtccggaa aacaaataaa
    39361 ggagtgtatg gttgaatgaa aatgaaagaa accttgcaat taggaaaaac aaaattccct
    39421 atgcgtggta atttgccaaa ccgagaaggc gagtggcaaa aagaatggga agaaaatcga
    39481 atctaccaaa aaagacaaga gttgaacgaa ggaaaaccta gctttgttct tcatgatgga
    39541 cctccatatg ccaatggtaa tatccattta ggacattcat tgaataaaat cagtaaagac
    39601 attatcattc gttcaaaatc aatgtctggc tatcgtgcac catatgttcc aggatgggat
    39661 acacatggat tgccgattga acaagtattg gctaataaag gcgtgaaacg taaagaaatg
    39721 tccatggcag aatacttgga aaaatgtcgt gaatatgcac tttcccaagt agataagcaa
    39781 cgagcagatt tcaaacgcct aggagttgca ggagattggg aacatcctta tgttacatta
    39841 gatccttctt atgaagctgc acaagtacgc gtatttggta aaatggctga aaaaggctat
    39901 atttacaaag gattgaaacc aatttactgg tctccgtcaa gtgagtcttc tttagcggaa
    39961 gctgaaattg aatataaaga tgtaaaatct ccatctattt ttgtagcttt caatgtcaaa
    40021 gacggcaaag atattcttga tgaagataca gcttttgtca tttggacgac aacaccatgg
    40081 acattgccag caaaccaagg tattgctgta aatccaaaat ttacgtatgt attggtggaa
    40141 gccgatggcc gtaagtttgt cgtagcgaaa gatttgctag aaacagtcca atcagaaatc
    40201 ggttgggaaa atgtaacagt tctaaaagaa tttgctggac aagaaatgga atatatgact
    40261 gcaagtcatc cattctatga acgtgaatca cttgtgattt taggcgatca tgttacttta
    40321 gacgctggta ctggattagt ccatactgct ccaggacatg gggaagatga ctatatcgct
    40381 ggtagcaaat ataaactatc tgtagtgtca cctgtagact caaaaggatt gtttacagaa
    40441 gaagcacctg gatttgaagg tatcttttat gacaaagcaa atcctatgat cactgatcta
    40501 ttaaaagaaa aaggagcttt gctgaagcta gatttcttta ctcatagtta tcctcacgat
    40561 tggcggacga aaaagcctgt gatctatcgg gcaactccac aatggtttgc atctatcgat
    40621 aaattccgtc agaatatttt ggatgaagta gaaaaagtag agtgggttat cccatggggt
    40681 aaaacacgtt tgtataatat gatccgtgac cgcggcgatt gggtaatttc ccgtcagcgt
    40741 gcatggggag taccacttcc gattttctat gctgaaaatg gagaagcaat catcacacca
    40801 gaaacaatcg aacatgtggc aaaattattt gctgaacatg gatcaattat ctggtttgaa
    40861 aaagaagcga aagaacttct tcctgaagga tttacccacc caggttctcc taatggcgaa
    40921 tttacaaaag aaaaagatat catggatgtc tggtttgatt ctggttcttc tcatgaagct
    40981 gttttacgtc agcgaccaga attatcattc ccagcagata tgtatttaga aggatcagac
    41041 caatatcgtg gctggttcaa ctcaagtatc acgactagtg tggctatcaa tggtgtagca
    41101 ccatacaaat cagttatttc tcaaggattt gctttagatg gtgaaggccg taagatgagt
    41161 aaatctttag gaaacatcat tgcaccagaa aaagtgatca aacaatttgg tgcagatatc
    41221 cttcgcttat gggtatctag tgtagattat gaagcagatg ttcgtgtttc tatggatatc
    41281 ttaagtcaag tggcagaagt atatcgtaaa atcagaaata cgatgcgttt cttattagcg
    41341 aatacagaag atttcgatcc taaaaaagat actgtttcgt acaatgattt acgttctgta
    41401 gacaaatata tgaccgttcg attgaaccaa gtaatcaaag aaatccgaga agaagggtac
    41461 gacaaatata acttcatgca tatttaccgt acagttatga acttcttgac ggttgatcta
    41521 tcgtcattct acctggattt tgctaaagat gtagtttata ttgaagcaga agatgattat
    41581 caacgtcgtt gcatgcaaac tgttttctat caaacagctg tagctttgac aaaattattg
    41641 actcctatca ttccgcatac agcagaagaa atctggtcat tcctgaaaga agaagaggag
    41701 tacgttcagt taagcgagtt tcctggttat gaagagtttg caaaccaaga agaattgatg
    41761 gatacctgga ctgctttcat ggacttccgt gataatgtct taaaagcatt ggaagaagca
    41821 agaaacagca aattgattgg taaatctttg gaagcaaaac taactgttta tccaaaacaa
    41881 caagttcgtg aaatgttaaa agctttggat gcagatattg cacaattatt gatcgtttca
    41941 ccagactact ttgaagttat ggcagcagat gaacaagtgc cagataacgc tatggtattt
    42001 gatgatgttg ctattacagt ggaaaaagca gacggggaaa cttgcgatcg ctgtcgccaa
    42061 gttcgtaaag atgtaggagt agatgaaaaa cttcctcatc tatgcggtcg ttgtgcaaaa
    42121 atcgttgaag acttctatcc tgaagctgta gctgaaggat tcgaagaaaa gtaaaaggga
    42181 aaagggggtg tgacatgttc tttgtcacac ccccttttgt tatcaatcgt ttaattttcc
    42241 acgttcacga taccagttat ctggttgcca gatccattcg aatccgtctt tttcaagtag
    42301 ttcgaaagct gctttaggtc ccattgatcc agctttgtag ttgggaaaat ccggttgtgt
    42361 ttggtcccaa gcttttcgaa tgacatccac gatatgccaa gattgagcga cttcttccca
    42421 atgagagaag ttcgttccat caccattcaa cgcatctaat agtaattttt cgtaagcttc
    42481 tgggctattt tcaaccattt ctgcactatt tctaaattcc aatttgattg gttccgtttc
    42541 aaatccttgc cctacttctt tcccattcaa ggataaagaa aatccttcag ttggctgaat
    42601 atagatcgtt agaacattag gtggaagtgt cgtatcgtca catggttcat cgacagatgt
    42661 tttgaataca ttaacaggaa cttgtttgaa tacgatgttg atccgagtcc ctttttcagt
    42721 caaacgtttg cctgtacgta catagaaagg aacacctgac caacggaagt tatcgatagt
    42781 gaatttgcct gcgacgaatg tttcagtctc tgattgagca tccactttgt cttcttcgcg
    42841 atagcccttg aattgtacac catccaattc accttgagca tattgcccgc gaacgaagtt
    42901 ttctaacact tcttcttcgt tataaatgcg gatagctttc aatgctttga tcttttctgt
    42961 acggatttct ttttcggaaa atgctactgg cggttccatt gcaagtaatg ctacaacctg
    43021 taaaatatga ttttgcacca tgtctttaag tgcgccacta tgatcgtagt agcccccgcg
    43081 atcttctaca ccgaggtttt cgccaaaagt aatttggata ttgtcgatat agcgattgtt
    43141 ccattgagcc tcaaaaatat tattggcaaa acggatagct gagatgtttt ggatcatttc
    43201 ttttcctaaa taatgatcaa tcctgaaaat atcttgttct gggaatactt ctctgatttg
    43261 ctggttcaat tcaaaagcag actggtaatc agaaccgaac ggtttttcta tgatcaaacg
    43321 attgaagcca ttttttgtca taatattttg tgatttcaaa tgagaaacga tcgttccaaa
    43381 aaattgaggt gccatagcca aataatagac acggttaccg tttaattgat agtgtccatc
    43441 taatcggtca gacaattctt ttaatgtctg ataatgcgtt gaatcattta catcatggga
    43501 ttgatagtaa aaatggcttg caaaggtagt tgcttcttca tctgaaggat tcaatgcacg
    43561 gattgtttct ttgacaactt cacggtagtg ctcatcgctc cagggacggc gagcggttcc
    43621 gattacagca aaatgctcgc ctaaatttcc ttttctgtaa aggcggaaca aagacgggta
    43681 caatttacgc tgggctaggt cacctgtacc gccgaatatc gtaaacaata catttttttc
    43741 attagacatg tggatacact cctttatatt ttatcgacaa aaatcgtgct ggccgcctta
    43801 aagctgacgg ggattttctt tctatcattt tggatagtga tcggtccttc ataagctgcg
    43861 atgtcaacga tctcatattc ttcgttgata ttcaggtcaa tagtgactaa gtaatccaac
    43921 aattcttttt catcaagcac tcgtgcgata cgcacttttg taccgacagg ataggactcc
    43981 aatgtttgtc ggcgttcttc atggacaact tcctcttttt taggaatcga tcctccatga
    44041 ggacaatgtt caggatgatt caaatagttt tctaaatgat ctgcaagatg ttccgaagtc
    44101 acatgttcca atacttcagc atcatcatgg acttcattcc agctatagtc taaatgttca
    44161 actaaaaaaa cttcccataa gcgatgtttg cgaatcagac tgctagcttt ttgcagtccg
    44221 cttgcagtca attgtacacc ttgataaggg gaatgttcta caagctcttc tttcacaagt
    44281 ttagaaatca tttcactgac agatgcagct gagacatcta gactagatac gatttgttta
    44341 ttgttgactt tcgttgtatc tccacctagt tctaaaatga ttttcaaata atcttctcga
    44401 tttggtgtca tattcgatca tcctttcatg gtaaaaaacc atcattagta agtgtaacaa
    44461 aaaaaacgtt aattgactat ttttctaaat aaaaaacaaa ggatttttag acgtttttac
    44521 aacaaaaaac gaaagatgat agagaagact cattctttcg tttataaagg atatatatat
    44581 acattgggag ggatctattt ttcagataac aacttatatg aagtgtctgc agattcgtca
    44641 taaagagttt gttcgggata agaaaagata agataaaaac catactgatc acgtacgact
    44701 aaacgatatt catctatttc taccacagat gtgccaagag actgaccgtt gatcaaaaac
    44761 gtgtaatcag atgtaatctg taattgttgt ttttgctggc tatcactaaa gaaccatgta
    44821 ccttgatact ttgagagtcc ttctgacttt tccgcttgtt ttttcttttt caagtaaata
    44881 aaacttgaga gaacggtaat gagtgaacca agaaaataga tcattttttt tatcaccaaa
    44941 tcactccttt atgagaaaat aatcgcatag acatattctt tcttctttat ttcattgtac
    45001 cgaataaaag ctaaaatttc tctaagactt tcgactggtt tttttactgt ttttctacaa
    45061 attatgatag gatacatagt aggaagaaag gtgacataat ttgaagtatc agcaagtgga
    45121 aatagctttt tttattgacc gcccgaatcg gtttatagca cattgtatga aaaaagacgg
    45181 agaaataatt attgcgcatg tcaaaaatac aggtagagga aaagaggtcc tgataccagg
    45241 cgctgaagtg gctattgtat ttgctcctgg acctaaacgg aaaaccgcct atgatctgat
    45301 tgctgtaaaa aagaagggtg actggtttaa tatcgatagt caattgccta atcggctggc
    45361 aattgatggt attttagacg gcacgatcct tttaccagga ttaactggtc catttacggt
    45421 atacaagcgt gaagtaactt atcttcactc caaatttgat atttatttag agacggtggt
    45481 cggacaaaaa gcatttgttg aagtcaaagg tatgacactt gaaaataaag cgattggtgc
    45541 ttttcctgat gcgcccacac tcagaggatt gaaacatata ggagaattaa cgtatgccgc
    45601 acaagatggt tatgccgctt atgtcttgtt tattgctcag ttcgaacatc ttcatctggc
    45661 aacgatccat gaagaaatgc aaccagcact agctgatatg gttcgacatg cgcagcaaag
    45721 cggagttcaa atcctcgcct ataattgtca agtatcggca gatgaggtaa ctgtcaagca
    45781 ggccattcca tttgatgtag atatcccttt tgaagatcct atacaataga aagaaggtaa
    45841 aataatgatc aacttaggta ttatcggaac aaattggatt actcatcaat ttgtccaagc
    45901 agctttaagc acaaaaaaat atgaattgac agcggtatat tctagacatt tggaaaaagc
    45961 acaggaattt ggttctcatt atgaagggga tatcgaattc gcaacagatt tgaagacttt
    46021 tttcaatatt actcatatgg acaccattta tattgcttct ccgaatagtc ttcactttag
    46081 tcaagctaag caagcaattt tggcaggaaa aaatgtgata gttgaaaagc cagctttttc
    46141 gacgccaaaa gaaatggatg aaatcatcca tttggcaaat gaacacaatg tgtatttttt
    46201 tgaagcagca agaaatatcc atgaatcagg ttttaaaaag attgccgatt acttaccatt
    46261 aaaagacgag ataatcggtg caaatttcag ctatatgaaa tattcttcgc gctatgacca
    46321 agtattagat ggagaagaac cgaatatctt ctcgactcat ttctcaggtg gtgcattgat
    46381 ggatttaggt gtttaccttg tatatgcagc tgttgcttgg tttggaatgc caaaagaagt
    46441 ccattatttc ccaagaaaga tttctactgg tgtagatggt cttggatggg ggatcttacg
    46501 ttatgagaat tttgatgtat cgatccagcc aggtaaaatc ggtgattctt atttaccgtc
    46561 agagatttat tttgactcag gaacgctagt gatgaatgga gtcaatgcaa ttgaacaagc
    46621 acaatttcat gatcgcgcgc ataaagaaat cattgatttg gcggtaacag ctgcagaaaa
    46681 tccaatggca gatgaagcag aggattttgc caatgtcatg gctcatccga aagatccagc
    46741 ttggggattg ttgtatgaag agtggatcga gctagctaga aatgtgaacc aagtgattta
    46801 tgatttaaga aaaaatggcg gcatcaaatt cgatgcagat aatgaggaag atttttaatg
    46861 aacgaatttg tacaagtatt tcccgaaaat tggcagaaaa aatatgagga taaagggttt
    46921 atctcacctt ctcttattca acgagcagtt tttcagccac taagtaataa acaaagtata
    46981 gtagcggttt ctcctacagg ttcaggtaaa acactggctt atctttggcc tctactacta
    47041 aacgtggaac caggtgaagc aagtgcgttg gtcatttttg cttcttctca agaactagct
    47101 attcaagtag cagatgttgc acgtgaatgg ggaaaagaca aagagttgaa agtccaatct
    47161 ttggtgggcg gagccaacgt caaacgtcag attgagggtt tgaaggaaaa accagaaatc
    47221 ttgattggta caccaggaag aatattggaa ttgatgaaag caaaaaaaat aaaagcacat
    47281 caagtgaaaa caatggtatt tgatgaagca gaccagctat ttgacgctgg gaacagccaa
    47341 atcattgatc aaattcttca tcaagctcca acagagtatc agctagcttt tttttcagcg
    47401 acagcagatc gttcccttga aagcattgaa aaaatcactg ggaaaacgtt tgagacaatt
    47461 gacgtgacag cagaggacga ttctcgaaaa ggactgagac attacttttt acgtgtaccg
    47521 atacgaaaga aagatgacta cttgagacgt ctcacgcata tagaagattt tcatggtctg
    47581 attttcttta atcaactgac tgaattaggc gtaatggaag aaaaattgct gtatagaggt
    47641 gtaccggtag gaagtctggc ctctgatcag aacaagctac tccgaaaagc agcgctagaa
    47701 caattcaaaa agaaaatggt cagagcactt ttgaccacag atgtggcggc tagaggttta
    47761 gatattacag gtcttcctta tgtagtgaat gcagaagttc cgttaagtga agaagcttat
    47821 ttgcatcgtt cgggaagaac tggtcgaatg ggtaatgaag gaatagtaat tacactcgta
    47881 caagataata atctaagaga tttaaaacgg cttttacgtc catcaaatat aacacttgaa
    47941 gagatttttt tatacggagg taagctgcaa actgagcagc caaccaaaga agatgcagct
    48001 cctgcagtaa ataaaaagta tgcgaaaact ttttctggaa aggagcagaa cccagaatat
    48061 aacaaagaaa aaataagaaa aaaagttaaa aataaatcaa aaaaagagag aaataaagga
    48121 gcaaggcgca aataagcgcc tttttatgct atgattatga aaacgggaac aaaattggtt
    48181 gccagaggag gggttatgtg aaagaacgtc aagaagagat cttgcagcta ttgacagaaa
    48241 accaacaagg attgacagca agtgatgtag ctgagcgctt aactatcgat cgaagcaatg
    48301 caagccgata tttaagtgaa ctatacaagg cccatcatat tgtaaaaacc gctggccgac
    48361 cagtcgttta ctctttgcca acggaaaagt caaaatctga tgaagtgcat gtcgactctt
    48421 ctacgcaagt gacttttgaa acactcgttg gagaaaatga ttctttaaaa gtcagcatac
    48481 agcaggcaaa agctgcgatt ctttatccac cgcgggggtt gcatacgatt atttttggag
    48541 aaactggtac agggaagtcg atgtttgctg aatgtatgta tcattttgca atcgattcag
    48601 agatgctttc tgcagatgcg ccatttgttt ctttcaattg tgcggattat gatcaaaatc
    48661 cgcaactgct ctttggacac atctttggga tcaaaaaagg ggcttacaca ggagcagctc
    48721 aagatagtcc cggtctaata gccaaagcag acggcggtat attgttttta gatgagatcc
    48781 accgtttacc gccggaaggg caggaaatgc tgtttacttt cattgataaa ggtatttacc
    48841 gtccgcttgg agaaagtgca caagtacatg aagcatctgt tcagatcatt ggggcgacga
    48901 ctgaatcttc agaaagtttc ttatctacgt tcaatcgacg gattcctatg gcaatcacct
    48961 tgccgaatct tgcttcacgt tcactggatg agcgttatga aatcatctct ctttttatca
    49021 aacaagaagc gaatcgtttg aatcaacgta tcgatatcga aaaagaagcg attcttgcct
    49081 tcatgcttta tgatgcggaa ggaaatatcg gtcaagtgaa acgagacttg aaactagtct
    49141 gtgcaaaatc ttttttacat taccgtactc atcatgagaa aaagctaatc attcgaaaag
    49201 aagaactttc ccttcaagta caaaaaggat tactgaaaat caaggaaata ccggaacgtc
    49261 tcgaccgatt catggacagc aaaagtcagt atttgacatt tgaaccagga tttgctgatg
    49321 ttgtctggtc acaagatcca gaacgaaaca tgcaggtcta taacgatatt gaggaaaaag
    49381 tcacttctct ttccgaaacc ggtgtggaga acattgatct agagaccctc atttcaaaag
    49441 atgtggatgc ttatttccag acatatgtca aagaattgac taaaagttcg attcccaaag
    49501 atcttttgcc agatgaaatc tggcggttaa ccaatcaatt gtatgatgtg gctgaaaaac
    49561 ggttagaccg tatttataat gaaaaagctc gttttgcttt tgctttgcat ctgcaaagta
    49621 cattggatcg tgtgagagaa ggtcatatga tcgtccaccc agatttgaat aacgtacgga
    49681 aaaattttaa gagggaattc caggtagcaa tcgatctttc aacgatcatt gaagaagaag
    49741 aacaagttga gattcctttt gatgaaatcg gctttattag tatgtttctt tctatcaatc
    49801 taggagaaag tgagcctgtt aaagaaaaca aagtagatgt tctcatattg atgcacggca
    49861 gacagactgc ttcaagcatg ttggagatgg cacaagaact attaggaaca aaagtaggga
    49921 aagcttttaa tatgccactg gttatggaag ttcaaacaat gtatgaagaa gtgttacaat
    49981 atgtcaaaaa ctatcaagag catttgacga atggcctact cttgttaaca gatatgggat
    50041 cattaaacac cttcagtgat ttgatttatg aagagactgg cattcggacg aaagctatca
    50101 cgatgacaag taccatgatt gtgatagaag cgatacggat ggcaagtgtt ggaagaagct
    50161 tagaagatat ttatcaaaat atccagcttt cctttgaatc gatcgtacgt gatcagttca
    50221 aagcggaaaa gtctgaaact ttacagcgta aaaaagccgt aatcgtgaca tgctttactg
    50281 gtgaaggagt agctgccaaa ttatatcagc gtattatgcc agtgattaat caaaataagg
    50341 tagaactgat ccagatgcag tttttagaac gtgaatcatt caaaaaacac atcgatgcct
    50401 tattggaaga atatgagatc aaagcaattg cgggaacagt tgatgttgat tatcaaaata
    50461 tcccattttt ttcagcctat gacgtttttg atgatgaaaa actaaatatt ttaaagcgta
    50521 tagctgatga tgagatcccg acagctaaaa ttgtcgattc acttgctgga tcattaagcg
    50581 atgtcttttc tattgatgaa ctgatccgtt cattgcaaaa gacagttcag cagatccaga
    50641 ccgatttgtc gattatcgtg gaacctggag tagatactgg aatcgttatc catttagcct
    50701 tcatgttaga cggattgatc aaacaagaaa gccatcggca atttgagaaa ctgtctattt
    50761 tctcaaaaat ttatcgtttg gaaatggata tcgttcgggc aaacttgatg gcactagaac
    50821 gaaaatatca ggtaaaaatt ccagaagatg atatcgcatt tcttacacaa atgtttcttg
    50881 aaaataaaat aaaaaaatga acacactaat catactgttt acacactaaa catctgtgtg
    50941 cgcactataa aaaagagcta aaaagcatga aaacgctatt tcagctcttt tttttattgg
    51001 catgcttctt gcgttatata aaagtgtaaa aaaataaaag gagtgttaaa aatggcaaaa
    51061 aaaacaatca tgttagtttg ttcagcaggg atgagtacga gtttattggt cacaaaaatg
    51121 caaaaagcag cagaagaaaa agggatggaa gccgatattt ttgcggtctc tgcctcagat
    51181 gcagataata atttagaatc taagaatgtc gatgtattat tattaggtcc tcaagtacgt
    51241 ttcatgaaag ctcaatttga acaaaaactt gcgcctaaag gtattccatt agatgtcatc
    51301 aatatgcaag actatggcat gatgaacgga gaaaaagttc ttgcacaagc agaaaatcta
    51361 atgaaataaa tcaagtatgc agttgggggt ataacaacgt ggaagatcaa caaaatctag
    51421 aagccatcat ggggttaatc atgtttggcg gtaatgcaaa gagcgatgca atggaagcga
    51481 ttgcggctgc taaaatcggt gattttgagt tagcggatag gaaaatcgct gatgcagaag
    51541 aatcacttat acaagcgcat catgcacaaa cagacatgtt gacacaagaa gcacaaggaa
    51601 atcatatgca agtgacatta ttgactgttc acagtcaaga tcacttaatg acatctattg
    51661 cgtttactga tttagcaaaa gaaatcatcg aactttatcg tcgcgtatac agcgaataaa
    51721 tacaacttct tttttgaacg gaagaagaaa aatttttgaa cggatttttt attttgttat
    51781 aaggagaact ctctttatat aaaaaactta taggaggaag taaaaaatga acggactatc
    51841 aagttggatg gagaaataca tcctgccggt tgccgcaaaa atcggagcgc aaaaacattt
    51901 agttgctttg cgtgatgctt ttatcggcat actgcccgca acaatggcgg gatcagtcgc
    51961 tgtaatgatc aatgcaatta ttcgtgattt accgcaacag tttaacagta cctatgctga
    52021 cagtttagca gcagacaaag gaatctttgc cgtattgaat gtcatcatcg gaatcaatgg
    52081 ttttgtctgg aacggtacac tagcaatcgc cggattgatc tttgcctttt cttgggggta
    52141 taatcttgcc cgagcttatg gagtaaatga tctagctggg gggatcgttg gtttagctac
    52201 cttgattcaa ggtatttcct ttggtccagc attatcagca gcattagatg tgaatgttcc
    52261 ttcaaatgtc gcagatgcaa tcaatagttc tgagattggt gcaacgattg cagatggcac
    52321 actgtcagtt ggattatggg gttggctaaa actagatcat ttgaatggaa acgcttattt
    52381 tacagttatg atcatgggag ctatttcagt cattattttt tgtaaattga tgcttgccaa
    52441 cattacgatc aaaatgcctg attcagtacc accagcagta tctaaagcat ttgcagccat
    52501 tttaccagcg acgatcgctt tatacgtcat tgctattatc aattatatcg taggtcgtgt
    52561 agctgatggg caactgatca ttgatttggt gcaaaaatat attgcagaac cattcctagg
    52621 attatctcaa gggttgggag cagtattgat cgtcacagta tttgttcaag tattctggtt
    52681 ctttggtatt catggatcaa atgtattggc accagtgcta gagggaatct ggggacaagc
    52741 acaactaatc aatattgata ttttccaaaa aggttataac ggaaaaactg gtacaccagc
    52801 cgtgttagat gcaatcgaag atggaaaagc ttatatgtgg gtccgcggat cgttcgatgc
    52861 ttttgcatgg tttggcggat caggcggaac gatcgtctta ctgatagcta tcttgatttt
    52921 ctctaaacgt gcagattatc taacagtagc taaattatcc attgggcctg gtatcttcaa
    52981 tatcaacgaa ccagtgatgt ttggtctgcc aatcgtattg aatgcaatca tgtttatccc
    53041 attcttgatt gctccagtag tagcaacagc aattggatgg acagctactt atcttggcct
    53101 agtcgctccg gtatcgcagc aagtcacatg ggtagtaccg ccgttcttat tgtcattctt
    53161 agcaacagga gcggattggc gggcaccgat cgtaacatta gtatgtatgg tcgtgacttt
    53221 cttgatttgg gcaccatttg tcatctctgc aaacaaaatg gaccctgccg caggcgaaca
    53281 acaataagat gaacgtgagg agcgggacgc tttaagtttc gttcctcata atgaattttc
    53341 gaggaggaac tgaaatgatt acaattgcca gtgcaatgca acaagatgaa atcaaagaat
    53401 tgttagaagg atacaatgaa gaaggaatga cttttacatt taaagaaaaa caaggaatca
    53461 agctgttctt tgaaacaagt gcagaagatc cggaagttgc ggctaaaaaa gcaaaggaac
    53521 taatcaaagc acagccttgg ggaacagtcc tttattttca atcaacagct gtttagaaaa
    53581 tggtttaaaa agataggatg gttgagatga taaaaaacgg tttattttta tgtagtattg
    53641 gttctttgat cgtgttgtat agtttgaatc cacattcgca aaggtatgat ttgtatagta
    53701 tggtcacagg tctttttcta acaggattag gaatctattt cttcatgaag gggaaaaaaa
    53761 gagaagaagc aaaggagaaa aataactaat ggaaatcacg aaaaaattaa atattccagc
    53821 atcgtttttt tacgataaag ttatggactc tgtccttttc gatgtacgta aagcgaccgg
    53881 caaatcagta actagaaaac agctgaaaaa tttggagtac gtcaaacaat tctcgcaaaa
    53941 taaccgggct cgcataaaaa tcgaagaagt cattgaaaac cagtcttata agtttcgtac
    54001 atcgacaacg aagaatgaat tcgtcgttca ttatcaaatc aaaccattgg acgattcgac
    54061 ctgtgaggtt cattacacag aaaaaatgga gtcttatggc atgcttcaaa agttgaatga
    54121 tatgctttta ggaacaatct tgatgtattt taaacggaga cgtttcaaaa aaatgctaga
    54181 tatgatcgaa gcaacgtatt aaatcaatga aacatggtac tatttagtta ttgaaaaatg
    54241 aagtaagcta gaaggaattt ttcataggaa gatagatctt tcctgcgaat cctcactagc
    54301 ttttttgtag gaaggggcag caaaatgaca aacaaagtaa gagagctagg tgtatcttcg
    54361 attgaggaaa tgtttgattt agccacttat gcatttaatg gggcagatac acctgaaagg
    54421 cgagaacgtt ttcgtacact tgcggagaat tcttggaatt acggattttt tgatgaggag
    54481 gatcggctaa caagtcaagt catggcgacc ccttttccag tgaattttta cggacaagag
    54541 tacctaatgg ccggcattgg ctatgttgct tcttatccag aagcaagggg acaaggcggg
    54601 atcaatcaga tcatggaaaa gatccttgaa gattgccgtg atcgtaaagt aagcttatct
    54661 tatctggcgc cattctccta tcccttctat cggcgctatg gctatgaaca atcatttgat
    54721 aaaatcagtt atcaactaaa cagtcgtgat gtgccgttta tcaaaaaaaa atctggaaaa
    54781 ataaagcgta tggattttga agatgcaaaa gctgcaatca gaagaattta tgaacagatg
    54841 ccggaaaacc aacgagctgg tctgaagcgc gaagactggt ggtatacgta taaattcaag
    54901 caaaaaggca attaccagtt tgctttgcat tttgatgata atgaggaagc aacgggatat
    54961 atcgtttatc agcttgcaac gtcttccttt attattgcgg agtggggatt tttggatcat
    55021 gatgcttttt gcagccttgt tcgcttcgta agttctcaca atggtgcttt tgaaacattt
    55081 gaatattcat gcggctacgg cggtaatgat caaaattatc tattagaaaa tccatttgct
    55141 tctgtaatga tcacacctta tatgatggcg aggatcgtag atatttcttt gtttttggaa
    55201 aattatccat ttaaaaagag acaagctgca tttgccctac aaatagaaga agatcattat
    55261 gcgaaatgga atgaaggaat cgtggaagta acaatcgaaa atggaaaaaa tcatctctca
    55321 aaagtagaac aaacaaaact cccaatcgtt cgaggaagta tccaacatat cacgcagcta
    55381 ttattagggt atcgtaaagt ggaagagttg gtattccaag aaagaataca ggtgacaaaa
    55441 gaatatgaag aaacgttaag ctcaatcttg ccacagcaac agccaattct taatgactat
    55501 ttttgataaa aaacgggtga tgacaatatt tttgtcacca cccttttgtt tttcatttgg
    55561 catttgaagg aaaatgttaa agtaaatcct cttttttcgt aaatttgaat tttttgtttt
    55621 cttttgtttt agggttttct tttttgtggt cttggattgc ttctttcgta atcttttccc
    55681 gatttttttt agatgaatct aagcgttctg cgtatacttt ttcttttggc ttatcattca
    55741 ttggaaagga cctccctaca ttatttcatt ctacctctag tttatcatct gttaaggact
    55801 agtggaaacg ttttgcctaa cttataagct gattttttta gcagataagc ttgcaagtaa
    55861 aaaacaaaca agctacaatt gatttattga aattgttcct gtagctcagt aggatagagc
    55921 aatcgcctcc taagcgatag gtcgctggtt caattccagt caggaacgta taaataaccc
    55981 ctgtatcctt tgcggtacag gggtttgttt tgtatttgtg ccaaaaatgt gccaaactag
    56041 ttatcatttt tatataaact atcgaacaca gtattgattt tttctttatc ctgatcttca
    56101 agctctcgaa caatatgaag ataagtagac attgtagttt ctaaactgct atgtcctaaa
    56161 cgtttcgata cgctaagtat atttactcct tgataaagta aaatagatgc atgtgtatgc
    56221 cttagtccat gcaaagtaaa ttgcttttca atccctaatt cttttaattt tttgcgcaaa
    56281 tatttgctga cggcgtttga tgaaactaat ccatttttta agttgaaaaa aacaaaatta
    56341 tgagggtttt tgatttcaaa attctcgaat aattcttttt gattgatttt aaactttttt
    56401 aagagatcaa tcgtatgttt atcaatggaa attttcctat ttgaagtttc gttttttgtt
    56461 tttccccatt catttaattt ataattccat gttttattaa tagtgatgat ttgatcttcg
    56521 aaatcgatat cttcccatgt taatcctaga agtccagcaa atcgcattcc agtggcacca
    56581 gcaactaaca cgagcatagg agaagagtac tgcgcagaaa ggttttcttc tacgagtttc
    56641 attaaagatt taaattgatc ataatctaaa tatttatctt cttttggctt caatgaatct
    56701 tttcctttga ttactgcttt tctagttgga tcaaacggaa ttaatccttc ttctacggca
    56761 tctttcaacg acgctctaat atggttatta aacttaataa cggtagattt tacatggtct
    56821 ttagcatact tatttaaaaa gcgttgatat cccactctat ctaaatcaga aatcaatacc
    56881 gctggcatat atttctttat gttcattaac gtatcttcgt attttctata agtgatagga
    56941 gatactgttc cttctttata aagttgcatc caatcctcaa agtaatctga taataataga
    57001 tttttgcgat cccctttaag gcctttgttc aagttatatt ctaattcgtt ggcggcatct
    57061 tttgcttctc cttttgtctt aaatcctgat tttcttatct tcgtgtattt tccgtcatct
    57121 tttttgtatg aaatttcgta ttgccaacta tttccacgtt tgactaatct tgccataatt
    57181 gaatcagctc tctttctctg atacaatagg aactataaag aagcccattg tttgggtttt
    57241 attatttttt gcacatcctt tttgcttgcc ggcgcaagga tgtgctattt gtcgttttaa
    57301 tggtataatt ggatgtgtat tagatcatcc aatcagaggt gtttattatg attaaagtga
    57361 tttttaaaag aataactgaa cttccagagt ttagattatt tgttgattat tggtatgtct
    57421 ggttttttat tgttgcattg ctgataggtc tagatgtcat attagaaaga aaacttaagt
    57481 aagagttgag ttaataaatt gaattcctaa atgagatatt ttgtagccca tattttgttt
    57541 gccgacatca cctaatacta tggagctaat cgttttttct aacagaccaa aatcagataa
    57601 tctatttaag ctaccatcta ttagctcttg tgaatagcca gacatgctga tatttccagt
    57661 gaaattttcg tttccacgac tcattaagca tgctaacaat tgaatctcaa tcgatgttaa
    57721 ttgattcagt acaagaagat aatactcctc gttatcccat gaagcgttgt taattcgaag
    57781 taaacaattc ttataaagat ttttatacat atctatttta ttttgtgcct ttgatttttc
    57841 tacctcgtca tttatccctt cgaatattcc aatgagttgg tccttgttct ctaagttgaa
    57901 aacatcttct ggaatttgat cgcgaatgtt ttctaatgat tcgtttaaat ttttgtagaa
    57961 tttctcgatg cgtttgaaac gcttctcgtt tttagaccca aaataaagtg actgcacaac
    58021 gccaccaata taaggaattg ctccaatacc gccttcaact attaattcaa gatattcttt
    58081 tttggttagt ttttcattgc tattatccat agttacctcc tattttgtca tttcctttac
    58141 aagcattgtg actcctgatg gcactctttt gtataggttt tattattgtg cacaatctaa
    58201 ctcttagtgg ggcgtggttc atttattttt tacttacttt actattaatc atatcccatt
    58261 gagcatagga tttttctatg ttcgatcctc ttgaactaat ttctcctgta aaagttactt
    58321 tatcgccctt tgtaaaggta tcagcattgt ttaagtcctt cgcaaaaatt acatatgaaa
    58381 ctttaggtgt tgcagaaata tcattccaac ttttatcatc gtactctttg tctgctataa
    58441 tggctattct agtagtcatt gattcgataa cagttccttc aaaagtatat gttttaccac
    58501 taatatattt agtaaaagct gtattttgct cagtagctgg agtaatagaa taataactat
    58561 ctaagaaagc accccagtca tgattatttg tctctaaaaa ttcttcaaat tgagttaggc
    58621 ttttattgct gctgttagat gtagtagttt gagtatcaga tgatgagctt tcctgtttgt
    58681 tattgtcatt tgcctcgttt gatgaggaaa gcgagaaacc tacggtagta aaaataatcc
    58741 cgataataag gagaatcata ggtgttttct tatttgtttt tttgataaat cttacaatta
    58801 acatgattaa acctataata aataaaacaa taccagtaaa accaaatata ccgtccatta
    58861 atagatcctc tttctctttt gatattgaat attataaacc aagcaattct tttttcttaa
    58921 aatcgaattc ttcttgatta ataatccctt catctaacaa ctctttatac tttttaattt
    58981 catctgcact tgaaatttgt gtttctttgg aattattatc taatatagat tgttgcttct
    59041 ctatatattt ttttaaattt tccatttcat tccaatattt ttttgtaaac ataacggtgt
    59101 tttcatcttt cgtggccgct aatatacctc cgcgactttc gtttccgcct agcaaggtaa
    59161 attgtatata accattactc atacctggtt tttttaattg tacggctgat atatttttaa
    59221 aggggatagt tttttctcct ttaatacctt gattaactaa atttataaat ccttttctaa
    59281 taattgaaat agaatcatca gttactttaa tcaaggtttt tcctggagat tttattaaaa
    59341 tctctttttc cattttttct tcctcatttc tgtgatatga ttttttttgt agaagctcat
    59401 atatgaggaa agagcccgtg ttgcagcacg ggctttttta atgttttgct gaaatcggtt
    59461 tttttaataa ttcttgatgt attcatacat attgccttgc gtaagaatat tttttcttaa
    59521 aatagcattg gcagacagca taacaagtgt atctgagctt attctgaata gaataatact
    59581 ccataaattt ttcgagatta aactgagatt catcagtcag ttcgttctca atatagatat
    59641 ttaataaaat tagaatagct attttatctg cttctgtttc aaattttgag tgaaaagttg
    59701 tagaagtatc gtacaaaact gaaaattcaa aatgagaggc gctgaaatgt gcaagttcat
    59761 gagataaatg aaaggcttct gcagtttcac cgtatagatt ttcattcaaa aaaatgattc
    59821 tgggttttgg atagtagaaa ccaggctctt tcatctccat ataaactact ttcaaattgt
    59881 attcgctcaa catttctttc aatttcaaat acatacaaac catcactcca actattcatt
    59941 ttcctctaaa gctttagcaa ttgcaatcgc tttacgcatt gtctccttag atatttcttt
    60001 tccatcaaaa gaaaaaacag tatcgtcttc tgataaatcc acatgtttag gggtttctct
    60061 ttcttctcta cctagaaggt agtctacaga gacatcgaaa tagtcagcaa tccgacttaa
    60121 ttcatctgaa ttaggagtat tatttttcca ctttgctaga taaccgttag aatatccaaa
    60181 attaatttct aactgccgta tagatatctt tttcctcttc gccaagtctt ttattatttc
    60241 ataggtattc atcgataaaa caacctttct aaatgtttac aaaaaaagtt tagaaaaata
    60301 cgcagaaata atttgactaa ttctgagtaa tgagctatac tatatcttgt aaacagattt
    60361 aacaactaaa aagacaacaa aaaacactat tgatatgtaa atgcagaccg ccaagaaagc
    60421 tttaaaatca atgtttttat gtcttattta attatgctct tagtatagag tattactcag
    60481 atactgtcaa ttgaatttag aaaaaagttg ttaaatttgt ttacgaatat aaaagaaagg
    60541 aatgagaaat atgaacacac cgcaaatttt taatttcgaa caaaacgaag ttcggacaat
    60601 tttagtaaat gatgaaccat attttgtagg caaagacgtt gcgagtgttt tgggttattc
    60661 aaacactaaa gatgctttgt cgcggcatgt agatttggaa gataagatgg ggtcgcgaat
    60721 cacgacctca ggtcaatcaa gagagatgac aatcatcaac gaatctggtt tgtacagttt
    60781 aatcttaaaa tcaaaacttc cctctgccaa aaaatttaaa cgttgggtaa caagtgaagt
    60841 gttgccagca attagaaaac atggaggtta tctaactcca gaaaaagtag aagaagcttt
    60901 gcttaatcca gatacaatca ttcaattagc aactcaacta aaagaagaaa gaactggaag
    60961 attaatcgca gaacaaaaga ttgcagagta cgaacctaaa atctcctatt tagatagcat
    61021 attatcttct acagattcag taacaattag tcagattgca gcagattatg ggatgtctcc
    61081 acaacagatg aataaattac ttcataaact aggtattcag aaaaaagtcg gtaaccaatg
    61141 gttattgtgc aaaaaacaca tgaaccaagg atacacaaaa tctcatacaa ctgagatccc
    61201 gaaagccgat ggtggcacta aaattgtaat gaataccaaa tggacacaga aagggcgtct
    61261 atttatctac gaattactaa aaaaagaagg atattaccct caaatggatt tagaggaaat
    61321 tggttagaaa ggagttttag tatgactgac attgcagaaa tcactcaacg agatagagaa
    61381 aaaatcaaag aatatgtcga aagttcaaag ttcttaactt acaccatgct tgctgaaaga
    61441 tttggaatta gcaaaagcta cttatcttta attttaaacg gtaaaaagac ttctgcagaa
    61501 gcaaacagaa ttatagattc gattatcact atgtacgaat tgtaaaggga ggaacagcta
    61561 atgcaatatc tagaagcaaa aatcccaatt ccagaaggct atgtaattat ctcccaagtg
    61621 gattatgagg agttaaaaaa agctgatgat actggtagat ggatgacgtt gccagaagtg
    61681 ctagaacgga ttaacagaaa atatgattgg tttacttcta gagttttaaa gaacccaaga
    61741 tatagaaata ttatcgatat cgagaaaaac aaaaatggat ttgtctatta tccagttgaa
    61801 ggaagagaca catatctatt tttaagaagt aaaacacttg aatttttaga aacaaatttt
    61861 tcggaaatct taaggaggca agcggatggg aaaatttaat agagcgctag tgttcagcgc
    61921 accgctaatc atctacgctt taggactttg gggaagcagg caagcgttga taggaacgat
    61981 tgtttacatg gtttggattt ttatggggct tgatgaagct gaagctgagt acagagcgaa
    62041 aaagccaacc gagggggctg actaaaaatg aatagaaaag agaaactaga atgtatatta
    62101 ctattactca gtttaattct ttcactaatt tctctattgg gaagtttgta tttttgatat
    62161 caacaatttt gtggatttgg gttctattta gagtaaatat catttttgtt tggtgattaa
    62221 ggagtttatt aaaattaatt ttccctactt caaatgcaag gtaacaagat atagcacttt
    62281 taggaggaat atttagcggt acagcttcag agtatattct attatcatcg actgatcctc
    62341 ctttagcaat taatttctta aatggagtag ctgaccatct gcggtttaag ttagcggatg
    62401 aaagttctaa attaactaac atagctggtt ctgttgaata gttagaaatg attacttttg
    62461 tataaatcat atctgcagcg aagtaagaag cattaagttc aacttctagt tgagggcgca
    62521 ttccttttat ttttatccct gttaaaaacg tactcaatat aaaacttatt attgacatcc
    62581 attgaaaaat tgttaagtga aaaaaattca aaataaacac caccagtttt taactaaatt
    62641 ataccaaaaa ggagagaaga aataatgcaa gaattagtaa ttttgaaaaa taaagaagct
    62701 gtgactacga gcttacaagt ggcagaaagc ttcgagaaaa aacatcaaca tgttttaaga
    62761 gatattgatg cactaaaaaa agatgtgtcc aattttggac agatgtttgt agaaggtaat
    62821 gaaccagatt catatggcag aaatcgacga gttttcttca ttagtagaga tggatttttc
    62881 ttgctggcta tggggtttac aggaaagaaa gctatctact tcaaacaaaa atacattgaa
    62941 gcattcaacg aaatggaaga tgttattcgc aagaatactg ttcctcaaac aattgaagat
    63001 atgatgatct atcaattaga agaaatgaaa gatgttaaaa aagatgtttc catgcttaaa
    63061 gatactatgc gaattagcgg acaacaagag tttgaaatta agcaaaaagg aaatatgaaa
    63121 gttatgggag ttctaggggg aaaagaaagc cgagcttatg aagaaatcag caaaaaagta
    63181 ttctcaaaat tttggtctga atttaaacgt accttttcaa tcccaagata tggcgagtta
    63241 cctcgtaaga gattcgatga tgctgtttca tttattgaaa tgtggttgcc agaaactgcg
    63301 atccgtatgg aaattgatca actgaacaga caacagagac tttttggtga tgacaatgaa
    63361 tagagctgaa gcgctaagaa tagggacggc aattgctaat tgctggtgga aatactataa
    63421 accaatcatc ctaagccaac aacatattga caagcaaaaa gcatggcaac aaataaaaaa
    63481 gtgactccgc cggcaagcaa agagtcacaa agaaaacaca tcataaggag attttagcat
    63541 atggaaaaag aactttccac tctagatcaa tatttgattg atcctgattg gggcaagccg
    63601 aaaattgagg aaacaagtgg tcgaaaaatc agacgaaatc ttttgacgaa tgaagaacta
    63661 gcttgggatc aagatgattt aggcaaccat gtaactattt gggatcatgt ttatcttatc
    63721 catctatcga agcattcgaa taaacctgaa tatatttacg tcatcgaaga tggcttgatt
    63781 gatgcgctag aagagtacga cagagataac ttgattgata tctcttatta cggaccaggt
    63841 aagaaataca ttgctgaaat ggaggcagaa tttgatgagt gaaatcaaag ggacaacgaa
    63901 ctttgaaaaa ctttttagtc gtaagttaaa taaaattctc aagaaaaaag gaaattttga
    63961 ttatttatct tgggctcacg cgtgggagat tatgaaaaag aatgatccac aggcaacggt
    64021 aactattaat gagtacaaac actacagggt tgtttctgga actcatcaag actttcttgt
    64081 tgaggaatat aaaccttttc ttatggatga aactgggact tatgtatctg tctcagtaac
    64141 ggttaaagga cacacggaaa ccgaattatt tcctgtttta gattatcgaa accaaccagt
    64201 tgttaaacca aatgcaatgc aaatcaataa ctcattgaag cgatgctttg tgaaagcatt
    64261 ggctctacac ggactgggat tatatgtatt tcaaggggaa gatattccaa caccacctag
    64321 aatcgataca aagaaattaa acatgctaga gacgattcta gaagctttca atgagcagat
    64381 gggtaaagat atgaccaaaa ccttaatcga atatgttaat gagcagacag ataaattagg
    64441 gctcttagct gataacgttg aaactattga acagttaagc tatgagcaat gtgccttgat
    64501 ggagcgagca atagcagcta agagaaaaga attagataag aagtgatatg agtgtttaaa
    64561 ccattaatcg attcatattc agcggttctg aaaaagttca aaggaaaaga cataagcgca
    64621 accatcaatg aggaagtgaa cattgatcga ctaaagacga tgtatgacgg ctacgatggt
    64681 gatcgagtca ttgaaattcg ttttattgat cctagacgtt tcaccgtaca gcaacgaaac
    64741 ttcatctatg cgctgatagg cgatattttt atcgatacag gcatgccaac ggacttctgg
    64801 aaggaattct tctactttcg ttttgaaggt gtcacagggc gcaaaataag cctgaaagac
    64861 gaatcgaata caactgtgag tgatgccaat gtcttagcaa atatcatctt agatttcatc
    64921 tttgaacatc atattccttt caaagaaggc tatgagattt tacctgcgaa tcaagaatat
    64981 tacttctaca aatgcatcac aaaaagagtc tgctgcatct gtggcaaaac aggagctgac
    65041 atcgatcact ttgacaaagc gctaggaaga cgaaagcgca aagaagttga tcatgcagag
    65101 tacacatttg cagcactctg cagaatccat cacacagaga agcacaaaat aggtgtgatt
    65161 aatttcaaaa ataaatatca aatcaaaggg atcaaattaa accagaaaac aatcaaaaag
    65221 ttaaatattg gaggggaaaa atgacagaac atcgaagtta ttatgcgatt ataccagcca
    65281 acgtaaggta cgacaaaaga cttaaaccaa atactaagtt gttatacgga gagataacgg
    65341 ccttgtgtaa tgaaagaggc ttttgttggg caggcaatga gtactttgca gatttatatg
    65401 gtgtgaataa agagaccata tcgcgatggg taagtgattt gattaagttt ggatacttga
    65461 atcgggaaat catttacaaa gagggtacca atcaaataat caataggtac ctacgaatta
    65521 atcaataccc tattgacgaa aaacgcaata cccctattga cgaaaaagtc aaagataata
    65581 atacatctat taataataca tttaataata caaaagaata tataagagag ttaccgcctt
    65641 cgaaaaaatc gaaggctaag cccgtccgtc ataaatacgg agagtataaa aatgttcttt
    65701 tgtcagatga gcagatggag aaactcaaaa cagaattccc taatgattac caagagcgaa
    65761 tcgaacgact gtcagagtat tgtgaatcat ctggtaagac ttataaaaac tatttggcaa
    65821 ctattcgaag ttgggcaagg aaagaaaaaa gtgaacctaa gaacgcaagc agtggataca
    65881 agcgcacagg aagacgagag aagcttcctg aatgggcaat cgaccaagaa gcctatctca
    65941 agaaaaaagc gctagaacga gctaatagac aatcaaaagc accattctaa gaggtggaaa
    66001 aatgaagatc gattatctag aactaattaa tgaaatagcg aattataaaa agggcgagga
    66061 attagacgtc ctgagagacg tatatgatca actcgaagaa gctggaattg aaggaattaa
    66121 gaatgatcgt tcgagttgga gtaaactcag atactatttc gcactctata tcgatggaac
    66181 gcaattaaga aatttagcat ataccaaatt actattcatt gattgtgtta aaggcttgca
    66241 aaaacatctt aatgaacttg agcaggtgta aacaagatgg acctaaagac atttacagca
    66301 cagatcgaat taatgcatca agaagcttta agacaaagtg tgtcgtacga agacaagtgg
    66361 ctcaacacat ttcatggcgg acgtgagagc gcacttgatc aagtactcaa attactgaaa
    66421 ggagaatgtc gggatggata agaaagcggc aatgcagcga attatcgaat tgacttattc
    66481 agaagattgg caggaagata aaaaaatagt tgcagaagtc caaaagctcg gtaaatcaat
    66541 gtggactgaa aagcccaaac ggagaacgcc gagaaagatt gcaatctggc atggtgatcg
    66601 aattctagta acgggtaccg ctaaacagtt atctgaaatt actggtctga gcaaaaatat
    66661 tatttgggat agagctagga gcttatggat tgattcaaaa ggaagacagt ttaggtatgt
    66721 ggaggagaaa taatggacga actaatcgcg aaagtagagc agtgggcaaa agataaggga
    66781 ttggatcaag cggatttcag caagcaaatg ttaaaaacgg tcgaagaaat cggggaagtt
    66841 gccgcttctc tagctagaaa agatgaacat ggtttaagag acggaattgg cgatgtagta
    66901 gtaaccttga tcatcttggc aatgcaaaat gatatggatt tatacgagtg cttggatttt
    66961 gcttatgacg aaatcaaagg tcggactgga aagatggtca atggtgtttt cgttaagtcc
    67021 agtgacctga aataattcca ttaatggaag aaataactga ataggaggat agacatgatt
    67081 gatgcaaaac aagtgcaaaa acagaaagat ggaatgttga tgtttgaagc atatgttcta
    67141 ccatttctta atcaatttga agttttggaa tgctctgcca gcggagaaga attggagtat
    67201 gttgtaattc gtgaaaccaa agaaaacgtt cagaagctaa acgaatttct ttgcactatt
    67261 aactgttggg atatgatagc tccaggattt ttatgtccag ctatgggaga atttttggaa
    67321 tattgtcgtc ttgaagatgc aggcactttg gatttagctt atctggtata caactaccta
    67381 aacatcaaca cagatcattt gtggtttggc actgccgaaa gaaaatgggt agtccgctaa
    67441 ccaccaatat caatgaaaaa aggcggtttc ctgaaagtgg aattgccgcc attgctgtaa
    67501 ggttctttac gcgactcaag gtcacagaaa tataaatgca aatctctttt gaagtgatcc
    67561 aaagctctcg gaaaatggaa gttttttgtt tcaaagaata aatgagattt gcgtcaagaa
    67621 cctgagagtt atttccaaaa aagcttccaa agaaccgaat gagctaagga catcatgtgt
    67681 aaacacataa tatagctctc ctttcacggc taatcataac atgaaaaata ttcgatgtca
    67741 gtaggaaaaa aggtgaatta tgaaaagaat attaaattat cccggcagta acagattctg
    67801 caattaaact ccgaagctga tgtatcagta tcaactgtag aatattatga gcgtggagaa
    67861 agtcaagcag tcacaaatgt aaaaatcgat aacgtcaacg gtcttatctg tttagatgaa
    67921 ggcgatagta tgaatgaaat tgctgcagac catgaattat cagaaactgc tttaattgat
    67981 caaatcgaat tagctagaca atactttgtt ccatatgcag atacctggtc caagcataag
    68041 aatgacatca tttttccaga ggaacaatga gagcaactga tccagtaatt atccttgagg
    68101 aagccaaatt tatttggact cacgaagaga tagagcaagc acgcttgctc ttttctcaag
    68161 gagttaagcc gagcaaagta gctgaaataa tgggtcaaaa gattcttgat gtcggattgc
    68221 ttttgctcca tctagcagaa aaaatttgat ttgaggtgaa aatgatgatt caacttgcag
    68281 gcatccaaac agggaaaatt tatttttctg gagaaagcaa aagcgaagcc aaccaatggc
    68341 tattgaaaac ttacacgaac aataagaagc taaggaaaaa atatcctgat ttgttgctaa
    68401 aggatgatca gattatgccg gaaccgatga ttttgacccg taaggaggga agttgaaact
    68461 aaaaaaccag ccgtgtgggc tggagttgct atttcttttt aataatgagt ttttctaaat
    68521 ttaattcatt ctcacgagtt tgcgtccaat aatcagaata atattttaat tgtttaagag
    68581 taggaatgtc gtcttcggta aaattagaaa ataattctgg agaattatct ttttttaatt
    68641 gttctaatcc tgattcttta aaacgttgtt caacgagttt tactaaattg ttgatattca
    68701 tgataaatca cctttttaaa tttaatttcg atttgattaa tcgatacaag tattatatca
    68761 aataaaaaag ctgatttagg gggtcttaca aaaacactaa aattttttca aaaagaggag
    68821 gaacggtggt gaaagtcaga gaacaattca agatagtgag cgacgaaggt aatgtttaca
    68881 aaataaagat cgttaatatt aatgaatatc gagaagcaga tcacaaatat ttggttgact
    68941 tatacatgaa cgataaatat ttgggagaag gattttgtgg agattcactt tttgatgatg
    69001 agcgaatttt gaaggaggaa acagaatgat ccacgaacta aaaatactac cagaatattt
    69061 tgaagcagtg acgagcggac gcaaacaatt cgagatccgc aagaatgatc gtgacttcaa
    69121 agttggtgat cagttaatac tacgtgaata taaaaaatac attaaacatg aattacctgg
    69181 actaacgaga ccaacattta gttacactgg tgactcatac aaagcagaga tcacttatat
    69241 tactgattac atgcagaagt ccggatatgt agtgttgggg attaaagggg tgaattaaat
    69301 gaaagtatac atcttagcta tcacagaggg cacatggatg ttcccagtcg gttccggaaa
    69361 aatctataaa tcaaaaacag ctgcttataa agcatttgaa aaatacaaaa aagaaaacgg
    69421 tggcggcact aacgcaaaga ttctagtggc tgataactgg catgaagaag gtgaacgtaa
    69481 ttgatttacc tgttcatttt cgtggtacta actattttta tgctagtaat cttattcaaa
    69541 aaaagatgag taaagacgaa cgaaaaattc tggccaactt ttatttagta ttaaaaatcg
    69601 aacaaaatgt gttttcggaa aggagaattg tatgggaaaa acaaaatcaa agattaagaa
    69661 gaaaaaacga cgtttggaac aaaaggcaat ccagaatgga acggctaaga aaaaataaaa
    69721 aagctacccc tttcgagata gcagcgcaat actattctac cataaggggt ggcgtttgtg
    69781 agatttcatt ggttaaaaga ttaccaagaa ctagatgagc agattcttta cttaaagtgg
    69841 aatcttaata aaagtaagct tgaattgaat cgatgggtct gtggtgattt agcaaacgtc
    69901 cgcatcgaaa agaattcgag aacttcttct ttagaagaga atatccaaaa gatagaaaat
    69961 gaattggaat tgttgatcga gcaaaaagaa gaaatgttat tgctgataga tagcttttct
    70021 ggtatcgata atcaaattgt taagatgaaa tatgttgatc aaatgagctt agaagatatt
    70081 gctgaatctg ttgggtatag ctcatcgtat gtcagacagc gacatgcaga aattagaaag
    70141 acattgaact ttttagatga gtatgaacac agacaagctg accgattgaa aaaagaaaac
    70201 gaaattgatt tttacaatag cgagaagtac aaagaacaac tctctttatt ctaaaattac
    70261 actgttcact aaatgttcgg tcattgtagc tatgtaaaca ttgttagcag catgatattc
    70321 tattagtgtc aaaaaaatat gaaagagcca agatatccca accgttttat taattggtat
    70381 ctgtggctct tttattcttt taattagtag ttggcataaa gttatttcca tttataaatt
    70441 gatcagctaa atcagcatca taatcagccg cgataaattg cgctgctgat ttaataaatg
    70501 catccatatc atgaacatct ttattagtat gtctacgaac atagtgcgtt tcatcattac
    70561 caatccaagt agcagctttg gctaatcttt ggagtttagg aaaatcattc aaataatttt
    70621 caattgtttt acctaataac atttttttta ttttatcttc atcctctgaa tttttagata
    70681 ttgcataatc tttaattaga aattctagag cttttctata accaactcca gcaatttgtt
    70741 ccaattgctc agatttagct tgtgtggctt gagtataaat atcaacaaat gtaggagaaa
    70801 ctttttcaat attttctggt aaatctattt taatcggcgg acggtaataa tctttaatta
    70861 aaatattttc agaatatcct tcatcttcat taaacgtatt tataaattgt aaactataaa
    70921 atttgttgca ctcatcattt atacactgta ctaatacgcc aaagattcta tcattatcga
    70981 acgcactata tgatgaaacc ccaaaataca catacggagt cattatattt ccgcaatgcg
    71041 gacaactatt tggcaaataa attgtctctg tattttgacg atcacgatac ttaatattaa
    71101 cttcttgaag cattaaaaca cctcgcatct tttttataaa tcataccaca aaatatctga
    71161 taggagagta aacaaatgaa tgattttcat gaagcggtac ttagtattga agtagaatca
    71221 agtttggcta aagtttataa gaaagcaatt gaagcagaga atagtccgta cagagaaaat
    71281 tggaatggta atcatgcaca tgtgcaagtg gagaatgatg attacagaac tggaatgaat
    71341 acgttagtta tttctttatt gtcacacact ctacccaatc tgcaggaaac gattgaatgg
    71401 tatgagcgaa tgggcgcaaa agtaatccgt acaaattaca aaggagagaa ttaaaatggc
    71461 aatgatcaaa attagaacat ccattagtgg aacagagtat tgggattcag aaaagaaaag
    71521 gacagtagtt gttccgaaag atcaagaacc aaattttgaa gtaaaagaag aaaaaggaat
    71581 tttgagtgat ggcaaatcat ttgttgctgt caatggcgaa ctcatagctc atagcagtga
    71641 aattcttgat agcgatggaa acactgctgc taattttgat ggagacgaag ctactaatga
    71701 tcagtccact gaagatacgg atgaactgga caatatgact gcaaaagaat tgcgtgcata
    71761 tgctaagaaa catggtattg atattcctgg tgctatccgt gcaaaaggcg atatcataaa
    71821 tcttattcgt gaagtagaat gaaatactgt cagtttgacg gatgcacgaa caaaatagca
    71881 aagggtatct actgtactga acacaagaga tcaagcagat cacgcaagaa gaagcagcaa
    71941 gcaaagtctg tttatcatca tgagaacaaa ccattctatc gaacgcaagc atggaaagat
    72001 atgcgtcaat ttatttatga aagagaaggt ggtcattgtc agcggtgtgg tcagttcata
    72061 tttggaaaga gagcacacgt ccatcacatt gtaccaatca aagacaacga actgcttaag
    72121 cttgatccaa acaatctcat gctattatgt tcaaaatgtc atccaattgt tgaaaacgaa
    72181 acggaagaca aaaaagtttt tccttcgtat ttcaattgaa gcccccctat tcattttcaa
    72241 aattttttcg cgtggggaga tagggtagcg gggagtcacg cgcatcgtta ggtcaaattt
    72301 ttcaaaaaac aaaggggggt gtatacaaaa atgacgacta aagcgcaacg taaagcgatt
    72361 attgatgaaa aagtaagtgc tgaaaaagct cgtatcttag aaataatgaa tttgtctgat
    72421 ttgtacacca tcactcttga tccattaatc gaatcatact tggatatttt tgaaatttac
    72481 caacacaaat atttattgtg gaaggaaaaa ggatttccgg agacgcaaaa attcacgaat
    72541 aaatcaggag ctactaatca atcaaaacat ccattggcac aacaagtaga aacttgggca
    72601 gataagaaga tgaaagctct agatttatta ggattaacaa acaaagcaaa aactggtaga
    72661 ctaattgctg gaggatcgac cgcaagaaaa gatgaagaaa ttacacgccc agaagtaaag
    72721 ccagtagatg aactagcagc gcacagaaat aaatggcgta agaaggcagg tgctgaaaaa
    72781 tgattgaacc tggtgtaaat tatgctgatt tatttgcaaa agaagtaaga aagaaaccta
    72841 agaagtatcc taagaccgtt cgtttagcaa tagatcgctg gtatcagtgg aaaaaaagaa
    72901 aagatatttg gtttgatgta gatcgcgcga atgaaatgat ggattgggta gaatcattta
    72961 ttgttcacac aaaaggagaa atggtgggaa aaccgtttct tttagaaccc tgggaaaaat
    73021 ttatttattc ttggatttat ggttgggtta aagaaaatga aaaaggccaa attgtacgcg
    73081 ttactcgtga ggcttatgtc cagattccaa aaaagaatgg taaaacattg attgctgtcg
    73141 gttcattagg atatgcaatg tacggagaag gggcgttatc agttgattgc tatgcttgcg
    73201 catctgattt tgctcaagcg caatatgctg ccaaaccttt tgcagttaca atcttaaaca
    73261 atccaatcct acttgaagga actaaaatat ttagggggcc aaagggaact gtttctagta
    73321 ttacttatga ctatattcat gaagatatgg cttactcaaa taaatttatt gttcaaacca
    73381 agaatattga taatatcgag ggatccaatc catattttgt attgaacgat gaattgcata
    73441 aacaggagaa aatggaacag tatgacaatt ttaagtctgc tcagatatct ttaccacagc
    73501 cattgatgtt taatatctca actgctggga aaggttcgtc gtctgttgga atgcgtgtat
    73561 atcgcgaagc aaaagaagtg ttgaaacgtg atgataatga ttcaaacttt gttctaatct
    73621 atgagccaaa taaaaattat gattggacgg atagaaaagt ctgggaaatg tgcaatccta
    73681 actggggaat atcagtcgat ttatctgctt tagaatcggc atttaaaaca gcgcaacggt
    73741 cagctcattc caaagctgaa tttctaacga aacacttgga tgtatttgtg aacggcgcgg
    73801 ataatttctt tgaacaggat caagtagagc catgtttagt taccacacaa gaacttggtg
    73861 atttaagtgg cgaaccatgt tatatcggtt tagatttatc acgtacacga gatttgacct
    73921 gtgtatcttt aaacttccca acatgggatg aagatggtaa agcggttctt aaagtaaagc
    73981 aactttattt tattccgaat gaagatttag agtttcgaga aaaagaagat aatgttcctt
    74041 acagtgattt ggctgaacaa ggtttcgttg aattttgcga cggaaaaatg attgatcaag
    74101 atcagatttt gcagtacata gaggactgca tgaatttata tgatattcag caagtgaatt
    74161 atgatccagc gatgagtgac aaacttgttg agaaattaga aaacttagga ttggaatgcg
    74221 ttgaagttgc tcaatatcct aaagtattga atgctccttt tgacgatgtc gaacggttgt
    74281 tttatgagaa acgaattcaa tttgataatc cattattcct ttattgcact ttgaacgttg
    74341 tagcaattac taacatcaat ggacaaaaag cgccaagtaa acgtcaatca aagaaaaaga
    74401 ttgatgggtt cgtggcgttt ttgtgtggtc ataaggaaac gatgaatcaa atgacagata
    74461 ttgattcaga tgagttagat gattacctaa gttccatcta tagataaata gaaaggcggt
    74521 gaaaaaaatt gaaattacgt gatcggttat cgaatgcagt ctattctttt atggaaaaac
    74581 gtggatatat cgaggatatt tttggacact acacacgtta tggtcaaaga tatgtgacgg
    74641 attcatctat catggaatct tctgatgttt atgaattagt tcaagacata tctaatcagg
    74701 tggcattggc cacaccaatt gttattggtc ccgacggcaa cgaagtcaaa gatcatcact
    74761 tactaaatat tttgaagagt cccaatgatt atttgacagg attcgaattt accaaattgg
    74821 aaacaaatac tttattgatc aatggtgaga cattcccatt aacggatagg gatcagcttc
    74881 atttggcgta cggtgtaaca actaaaatca atgaacgact tcaagaagaa tttgaaatga
    74941 atggtcaaaa aatacctggt caaatgattc gacacattaa gaacatcgga actgattcat
    75001 taaaaggtgc tggaataatt gatcttgcaa gaaacactct agaaggcgtt ctgagcgctg
    75061 aaaaagtttt gacggacaaa tatactaaag gcggtttact tgcgttcatg cttaaactag
    75121 acgcccacat caatccaaat aatagcgccc aaacaaaaat tgtcaaagct atattggatc
    75181 aactggaagg aacgcaaaat gagagtgatc attctgttaa gatgattcct ttgggaaaag
    75241 gatattccat cgagacatta aaaagtcctg ttgatgacgc ggcaattttg aattatttag
    75301 gtgtttacaa aaaagactta ggaaaatttc taggaatcaa tgttgatacg tatcaatcgc
    75361 tgatgaagac agatattgaa aaagcgatga tgtatctgca caacaaagca atcaaaccaa
    75421 tattgaaaaa caagagcgaa cattacaccg ctcttttttt tatgcctaat tctggctata
    75481 gagtggaatg gaaaattaat attttggatt ttgttcctta ctcaacaaaa acaaatattg
    75541 gctacaacat cgttcgtacc gggattacaa gtccagataa cgtggcagaa atgcttggtt
    75601 ttcctaaaca gaatactcca gaaacacaag ctatctatat ttcaaatgac ttatctagga
    75661 ttggccagaa aaatgcaaca gatgattcct taccaacgaa tgatcaagac ttgaaaggag
    75721 gtgatggaaa tgaagaagaa ggaaattcgc acgattgaca tcaccaatct ttcaacacgt
    75781 tccgatgaag aaactcatac gaggaccatt agcggctacg ctgctgtatt caacagtcaa
    75841 acacttttat gggatgactt aagcgaagtg attgttcctg gtgcattctc aaaggcaatt
    75901 agtaattcgg atgttcgttg tttgttcaat cacgattggt ccaatgtgct aggacgtact
    75961 aaaagcggaa cccttcgcct tgaagaagat gaacgtggtt tgaaattcga agttgattta
    76021 ccggacacaa cggtagcaag ggacttagtt aaatctatgg aacgaggaga catcaaccaa
    76081 tgtagttttg gttttgtgcc gactgaagaa acgtgggact acaattctga accaatgctt
    76141 cgaacaatcc atgaagtgga attatacgag gtttctattg tgcctttgcc agcatacgaa
    76201 gatacagaag ctgcattaag aagtcgtgat gaattagaaa aaaacgtcga agaaagaaaa
    76261 aaattaatca aaaaaattaa tcaagcgcta gaagcgtagg aggaaaaata catggataaa
    76321 gaattattga aaaaaatgaa ggcacgtcgt gagcaacgat tgactgaatt acgtgaaaaa
    76381 gttgaatcag gagaattacg cgaagcagat ttagaagccg tgaaagaaga aattgacagt
    76441 gttattgatg aattgaacgg aattaaagac gaattaggcg cagattctgg aactgatgaa
    76501 acagacgaca atacagatga tcaatcgaat agtacggatt cagacgaaag ccgttctggt
    76561 gaagacaacg atcaagaaga agattcagac agtgaagata gttcagaaaa tcgttctgga
    76621 atgattactc aacagcaacg agatggatta cttggatcaa ttaagaacgg attggaggca
    76681 cgtgcaaaaa tgaccaagaa acaaaaagat caacaactac gaaaagcatt tgctaatttt
    76741 gtagctggaa atatttctga agcagaagct cgagctttag ggattgaagc tggcaacggt
    76801 tcagttactg tcccagaagt aattgcatct gaagttatta cttatgctca agaagaaaat
    76861 ttacttcgta aatacggaac agtggtgcga acatcaggag atgtcaaata tccaattctt
    76921 gtgaagaaag cagatgcgaa tgtaaacaag aaagagcgtt caactgatat tgctgaaaca
    76981 gctattcagt ttgatgaaat tttgcttaat cctgccgaat tcgatgcttt ggcaacagta
    77041 actaaaaaat tattaaaaat gtctggtgtt ccagttgaag atattgttgt ggaagaattg
    77101 aaaaaagctt atgtgcgtaa agaaatcaat tatatgttca atggtgatga cgctggaaat
    77161 gaaaatcctg gtgcattagc caaaaaggct gtagcattta aaaaaccttt agatctaact
    77221 gcttcaggtg ctgggcaaaa attatatgat gcattaatcg aatttaaaaa tacaccagtg
    77281 acagaagtga tgaaaaaggg acgctttatt attaatcgag ctgctttgac tgccattgaa
    77341 aaaatgaaaa cagatgatgg atttcctttg ttgcggccat tcacacaagc agaaggtgga
    77401 attggttacc aattagttgg ctatcctgtg gattggacag atgcagcaga taaaaagggt
    77461 gaaccagaca cgccagtttt atattttggc gatttttctg catttaaaat tcaagaagtt
    77521 attggtgcct tggaaattca aaaacttgtt gaaaaattct ctggtaaaaa tcaaattgga
    77581 ttccaaattt acaacttgct agatggtcaa ttggtttatt ctccatttga accggcagta
    77641 tatcgctacg aaattacaaa accagttggt ggttaagatg gaagagcaaa ctaaagaatt
    77701 gtctttagag gaaaaattca aatcacatat tcattttgaa gagggcatgg atgattcttt
    77761 gctctctttt tatttaaata tggcaaaaga ttatgtcaaa acagcaactg gtggccaaca
    77821 agaatatctt attttgatgg ttgccggcat tgcctatgaa tatagagttt cagaggatga
    77881 actcgacaaa gctatgaatg ccatgacgcc atttatcgtg caaggagcga ttcaaaatgc
    77941 cgaagagaca gaccaataat ctcagatgga aagccgaatt gctagacatc aaaacaggaa
    78001 cagacggaaa cgatcgtcca actacaattt acgaatttaa gcgtctaata ttctatgaag
    78061 aactcggtgt gacttctcaa gaaaaatatt tatcacagca agccaagaca gacgttgtca
    78121 gacgaattaa agtcagatgg gataaatcca tcacagagaa attaagtgcg ctcaaaattg
    78181 attctgtaac gtataacatt actcgcattt atacgaatcc cgatgcaaga gaaatggagt
    78241 tgagtttagc ttatgtcgat tagctttgat gaattgaaaa cagcgctgaa atcaacaaag
    78301 ttagcagtgt tcagagacaa agccagatta gggacgatgt atccatacat tgtgtactca
    78361 aatgtgagta acagcaaaaa aatggcatcc ggtaaagtct ataaaaaatt accttattac
    78421 caagtctctt tttttacact tggaacagaa caggatttag ttgttattga acaagcgctg
    78481 caaaatgctg gcattccata ttcagatttt acaggtatac aaggtgatga gaacgacgat
    78541 accgtaacca actattacac atatgtgagg tgtgtggaaa atgccaagta ataagaatgg
    78601 tttttctgaa atatcggatt atttaggaaa cctttcaaaa gttgatccga aaaaattatc
    78661 gttggaatct ttagaagaag cagctaactt ttatctaaag cagttgcttc ctaatattcc
    78721 taagtcgctc ttaaaaaaga aacatatgcg cgatcaaata aaagtagtag ttgaaaacga
    78781 tcaagtgaaa gttcaatttg aagagacggc cttttactgg cgctttgccg aaaatggcac
    78841 aacaaatcaa cgtgcccaac attttgcaag tggtacgtat gaacaaaaca aagaaaaaat
    78901 tgaagaaatt atgactagaa aaatacttga tttatgggaa gggtgatttt aattgggaaa
    78961 acaagatact ttttattttg aaggattgga cgacatttta attgcgatga tggcaacgcc
    79021 agattctgtt ggaactgcac cgacttatag tgaagtttta cgattgccaa ttgccacaaa
    79081 aatcggtgtc aaagggaatg gaacagcatt agaaaaatgg gcatccagca aaatgtttcg
    79141 tcgtgtgtcg cgagaaacaa aacatgaact tgcgttggat cacgtgggta ttccgataga
    79201 agtgatggat gaaatcaaag gattagttgc taaaagcgga gtaacgttta gcaaaaatac
    79261 cgcacgagaa tttccgtact tcgcctttgg atttattgga aatattgaaa atggcggtaa
    79321 aaaagcagtt tggtatccta atacacaact atccaatgtg attgacgaag agtatgccac
    79381 tgcagaggaa gaaacaaaaa ttgacgatgt aactgcaaat ctggtttcca tcggactgaa
    79441 atacaataat gtgatgtatg caagttttga ttcaaataga gacggagctt ctctagaatt
    79501 atttaataaa ttcattgctc aacctgtata cgatgaagaa cagtggaaaa cattggctaa
    79561 agttggaggt gcgggttaat ggctcggtta tctgattatg gaattcacgt tgaagactta
    79621 aaaaattctg ctgttgtaat tattcaaggc gcagaattcc ctatttcatt tactatgcaa
    79681 acgatggaat ttatagcaga tgtgtatggt ggagattatt cgcaatttga atctgatatg
    79741 aacgccatgc tatctaaaaa agaaggacaa atttcttctg ctaacttatc gcctagtgat
    79801 ctaaaaatca tgcgtgcctt gatttatgcc atgctgcgta ctggtggttt agaggaagat
    79861 ccagaaacta ttttcaaatt tttgggaatg agtggagagg tgttgtctgc ttatagtacc
    79921 tgtatggaaa tttttgctag ccagacattt caggtggaag acctaaaaaa atccaagaag
    79981 ccacaagact ttcaaaaagc gcaagcaaaa agaaagaaaa acaaaaagaa tcggaagaga
    80041 taggaactcc ttggagtttt tatatttacg ttgctctcac tctattgaat tggagtgaga
    80101 gtttcttttt aaagtctaca cctaacttgt ggctcaaatc ttatttacag tggttacaac
    80161 aaaacaccga ttttgaacca cctcaatctg taactatgga taaatcgcct tggtggtaga
    80221 aaggagcgct aagataaatg gctggtaaag aatctgatgt cgttcttaat tttaaaacga
    80281 atggcgaagt cagttattcg aaaacaatca aagaaatcaa caaagaaatg aacttagccg
    80341 ctgccgagta caaaaaccaa gtgtctgcga tggacaagga tgcaactcaa acagaaaaat
    80401 tgcgagcggc taaacaaaaa ttagaaaaac aattaggatt ggctgaacaa cgatctcaaa
    80461 tgctgagaga ggaatatgaa aaatctgtca aagaaaccgg tgaatattct gctgaatcag
    80521 aaaaacttta taaacaatta ctcaattctg aaaccggaga aaataaactt cgtacagcat
    80581 tagaacagac gaacgatgca cttaaagaac aaggtgacgt ttctgttgat acagcaaaaa
    80641 aactccagaa aatcgaagaa acaggtgaga aagtaaaagg cgttggtgaa aaaatgtctg
    80701 ttggagtaac cgcgcctatt gtagcggcag gagcagcagg acttgcagca tttggtgaag
    80761 ttgacgaggc acttgatacc atcattacaa aaaccggagc aacaggtgat caagctgata
    80821 gactttcaca gtctttcaaa aacgttggtt caaatactca tttaccttta caaacggttg
    80881 gggaagctat tggtgaggta aatacacaat ttggattcat ggataaaaaa ctggaagatt
    80941 caaccaatta tctcctacag tacgctgaaa tcaatgatac agatgtttcg caatcagcaa
    81001 tatctgctcg acaagctatt gatgcttatg gactagaata tgatgatttg aattctgtcc
    81061 ttgatgtaac aacgaaaaca tcgcagaata ctggtcaatc tgtagacgac ttgatgcaaa
    81121 aagcaattga tggcgcacca caaattaaac aattagggtt gagctttggt gaaggggtca
    81181 ctttacttgg acaatttgag caatctggtg ttgattcaag cgcagcttta agtagtttat
    81241 ctaaagcaac agtggcttat gcgaaagacg gaaaatcttt aagtcaagga ctagaagaac
    81301 tacaagacaa ggtaaaaaat gcaggttctg aaacagaagc catcaatgca gcagcagaag
    81361 tattcgggac taaaggcggt cctagaatgg ccgatgcaat tcgtagaggt actttgaacc
    81421 tggaagattt agcaaaaact gctggagaaa gtgggggagc tgtaggagac acattcgatg
    81481 ctactctcga cccaattgat caagccgatc aagctatgaa caatgcaaaa ttagcaatgg
    81541 ctgacgtagg tgaagcagtc caagtaagcc ttttgccttt ttttgaaaaa gcaacttcct
    81601 tattacagga attctctaaa tggtgggggt ctctagatca agatacaaag aattggatca
    81661 taacaattgc tggtatagcg gcagcagttg gaccagtact aatcgttctt ggttcactta
    81721 tgggatctgt tacaaaaatc gttggggaag ttaaaagttt tataggagtt tggcaaggac
    81781 ttgctggttt atttggaatg tcgggaggct ggtttgcatt agcagttata gctattggcg
    81841 cattagttac tggactaatt tgggcatata ataacgttaa atggtttcat gatggagtga
    81901 attctttctt caaaggtgtt tcagatgtag ctgttgaaat atttaatttt ttaagtggtt
    81961 attttggtgg atttttcgat ggtgttatag caaatttcaa taatttttat aatgctggaa
    82021 aacgaatttt cagtggtttt ctagatttta tcactggagt atttacaggg aattggtcaa
    82081 aagcatggca aggtctagtt gatatttttg gaggtatttt cgatggtatt gttgctgtag
    82141 ggaaagctcc tattaatgcc atgattggat tgatcaatgg atttattggt ggattgaata
    82201 atataaagat accaaaatgg gttcctggtg taggtggaaa atcattttct atttcaaaac
    82261 tgccttattt agcacaaggc ggtcatctaa tcaatggaca agcgattgtt ggtgaagctg
    82321 gacctgagtt actgactgcc aagaatggta aaaccacagt tactccatta tcagacgaag
    82381 aaaaacgcaa agggatcagt ggaagagttt ctggaggtag cattgaacag catatacaca
    82441 ttggcaaagt cgatgcaaac aatccatctg agttagatcg tatgaatcgt aaatttgcta
    82501 aagcaaacaa acaggctatt cgtgatttgg gaggtgttcc tatttgagtc gacaatttat
    82561 gaatccagat gaaccaaatt ttatttggaa aaatcggaat gcagtaattg atatgaattg
    82621 catcattgag gcagagcttc cagatattat gccgaacaag cgatacgaaa cttacacgat
    82681 tcagggccga agcggagaat tgacggagac gtttgatgac tatgaacctt ttgatttgga
    82741 aatagaaggg atcactattc cacattcgaa actgagagaa gtcaaacgat ggctcactgg
    82801 taaaagccaa ttaatcacac ataatgatcc agacaagtat ctagaggcta tctgcagcat
    82861 ggataaagaa gtccctttcg aaaacgagtg gggcttcttt tatacattcg atgttacttt
    82921 tcgttgtcag ccactcaaaa gaaaaatcgg tgaagcacct aaaatttttc attctagtgt
    82981 tatggatatt tttgatcatg gtgacgaaat tgcacatccc tatctggaaa tagaatcgaa
    83041 cggaggagat ataacgatcg ctgtcggtga taaaagccta acaatactta atacgttagc
    83101 tgcaacaatc gtggttgata ctcagcttgg aaaagcaata caagaaggtt tgaatttatt
    83161 tacgcgtggt gattggccag tattgcagcc tgaatggaat caggtaaaaa tatccggaaa
    83221 atttaaagaa gtgcggtttt ggaataggag tgtgtatctg tgacgcaaga atttatttat
    83281 gcttataaaa aaatgccaga tgatttgagc gtgaacggag cgtcgttagt tgattgggaa
    83341 gatttgccag aaatcaatcg tgtgctgaat ggccaatatc gtttttatgg taactattca
    83401 agaagcggac agtatcgctc ttatttaaaa aaaggaaatt ttataaaagc gaaggtacca
    83461 gatggatcat ggcaatattt tgaaatttat aatgtcaaaa agaatttgac ctccgtttct
    83521 gtaacagctc ggcatattgg ttttatggcc aataagaact ttattgtcaa gtcgtttacg
    83581 gataacggca atgggtctca gatcatgacc aatcttaaaa acagtttggc atttgatcaa
    83641 aaatttaact atctttcgaa tgtagggaca acgcaccaat ttacagcaag acaagtcgcg
    83701 ccagttgaag caatcattgg ttcaaataac ggtaatcaaa atttgactgg cgtgactagc
    83761 gcggaacttg atatggataa ctatgatttg aaactggtaa aacagattgg atcagataat
    83821 ggttttcgga ttgattttgg catcaattta gaagcaatcg aagaagaaat tgatgaagaa
    83881 tcaattgtca atagtttgta tttggttggc ggtgttcctg ataacgatta tgatgaagac
    83941 aaagaaccta tcgaatatgg ttatttagaa attgatggag taaccaacga gaatcgacgt
    84001 attgccaaac gtgaaaacgg agattgtaaa acagttgatg aattgatcaa atggggcaaa
    84061 accttatttg acaatgatcg tatccatgag ccaaaagcta ctcatacagt cagtatggtg
    84121 gcgttggaac acacactcga atacggtgac atgtatcaag agctagcgtc tttacacttt
    84181 ggtgatgtcg ctcatgttag ggcgaaagag ctagatatcg agataaaaga gcgtatggtc
    84241 gaatacactt atttcccaac gcttgggaaa tataaggata ttgttttagg taatgattta
    84301 tcactgtaca cttcggcagt aaatactcaa gcacaagaat tgaaaaagaa aatcgacaat
    84361 cgaacagaaa cgttagttca aaatgtgttg aatgcgacgg catggatcac tggtaattct
    84421 ggtgggcatg tcgtttttcg tccagaaaaa gctccatcag agattcttat catggatact
    84481 ccaaatgtgg cgaatgcaaa gcgagtgtgg cgttggaatt taaatggctt aggttattca
    84541 gacaacggag taaatggccc gttcggtatt gctatcacat caaaaggaga aattgttgct
    84601 gacttcatca aagtaggaac aataaatgca gaagtattcg aaacttcctt taatgcttat
    84661 ggtgatgtgt taaaacttgt aaaaggcacg cttcaaattt ggaatgaaaa caaaaaaatc
    84721 atggagctaa ccaaaaaagg tatggaattc tggaatagaa aagaatccat tggaacgatc
    84781 ggaacaacag attcagcagg aaatccattt ccaaatgctg taacacctac acctcttgag
    84841 gaaaattctt tggtaatacg tacaaatggc gatggaaaat acattttaat ttctccaact
    84901 gcagaaaaag gatttgtgtt attaggaaac ggaaaagcat attatttcgg tgatttagat
    84961 attcagggaa aacttactgt tagaggtaaa gaagtgatac caggacaaaa tggcggtcca
    85021 tctggcggag gagaaacacc tggtgggtat cctgatgaat taaaaacaga tgcagaaaag
    85081 agagcttgga gaat
//
LOCUS       DAZKCH010000004        76005 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000004 DAZKCH010000000
VERSION     DAZKCH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 76005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.004"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            8..640
                     /locus_tag="ACG84X_000293"
     CDS             8..640
                     /locus_tag="ACG84X_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126201.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(774..899)
                     /locus_tag="ACG84X_000294"
     CDS             complement(774..899)
                     /locus_tag="ACG84X_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFP9126202.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1033..1926)
                     /locus_tag="ACG84X_000295"
     CDS             complement(1033..1926)
                     /locus_tag="ACG84X_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFP9126203.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEIAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(2108..3034)
                     /locus_tag="ACG84X_000296"
     CDS             complement(2108..3034)
                     /locus_tag="ACG84X_000296"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFP9126204.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(3119..3880)
                     /gene="pflA"
                     /locus_tag="ACG84X_000297"
     CDS             complement(3119..3880)
                     /gene="pflA"
                     /locus_tag="ACG84X_000297"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFP9126205.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(4124..6355)
                     /gene="pflB"
                     /locus_tag="ACG84X_000298"
     CDS             complement(4124..6355)
                     /gene="pflB"
                     /locus_tag="ACG84X_000298"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFP9126206.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6632..9082)
                     /gene="parC"
                     /locus_tag="ACG84X_000299"
     CDS             complement(6632..9082)
                     /gene="parC"
                     /locus_tag="ACG84X_000299"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFP9126207.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(9094..11139)
                     /gene="parE"
                     /locus_tag="ACG84X_000300"
     CDS             complement(9094..11139)
                     /gene="parE"
                     /locus_tag="ACG84X_000300"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFP9126208.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(11305..11739)
                     /locus_tag="ACG84X_000301"
     CDS             complement(11305..11739)
                     /locus_tag="ACG84X_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFP9126209.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11866..12504
                     /gene="plsY"
                     /locus_tag="ACG84X_000302"
     CDS             11866..12504
                     /gene="plsY"
                     /locus_tag="ACG84X_000302"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFP9126210.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12636..13511)
                     /locus_tag="ACG84X_000303"
     CDS             complement(12636..13511)
                     /locus_tag="ACG84X_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFP9126211.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13593..14384)
                     /gene="codY"
                     /locus_tag="ACG84X_000304"
     CDS             complement(13593..14384)
                     /gene="codY"
                     /locus_tag="ACG84X_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFP9126212.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(14402..15802)
                     /gene="hslU"
                     /locus_tag="ACG84X_000305"
     CDS             complement(14402..15802)
                     /gene="hslU"
                     /locus_tag="ACG84X_000305"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFP9126213.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15816..16364)
                     /gene="hslV"
                     /locus_tag="ACG84X_000306"
     CDS             complement(15816..16364)
                     /gene="hslV"
                     /locus_tag="ACG84X_000306"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFP9126214.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(16401..17306)
                     /gene="xerC"
                     /locus_tag="ACG84X_000307"
     CDS             complement(16401..17306)
                     /gene="xerC"
                     /locus_tag="ACG84X_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFP9126215.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(17504..18880)
                     /gene="trmFO"
                     /locus_tag="ACG84X_000308"
     CDS             complement(17504..18880)
                     /gene="trmFO"
                     /locus_tag="ACG84X_000308"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFP9126216.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18849..20927)
                     /gene="topA"
                     /locus_tag="ACG84X_000309"
     CDS             complement(18849..20927)
                     /gene="topA"
                     /locus_tag="ACG84X_000309"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFP9126217.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(21049..21906)
                     /gene="dprA"
                     /locus_tag="ACG84X_000310"
     CDS             complement(21049..21906)
                     /gene="dprA"
                     /locus_tag="ACG84X_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFP9126218.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21962..22729)
                     /locus_tag="ACG84X_000311"
     CDS             complement(21962..22729)
                     /locus_tag="ACG84X_000311"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFP9126219.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22722..23582)
                     /gene="ylqF"
                     /locus_tag="ACG84X_000312"
     CDS             complement(22722..23582)
                     /gene="ylqF"
                     /locus_tag="ACG84X_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFP9126220.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            23842..24240
                     /locus_tag="ACG84X_000313"
     CDS             23842..24240
                     /locus_tag="ACG84X_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9126221.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24477..25019
                     /locus_tag="ACG84X_000314"
     CDS             24477..25019
                     /locus_tag="ACG84X_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFP9126222.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(25102..25653)
                     /gene="lepB"
                     /locus_tag="ACG84X_000315"
     CDS             complement(25102..25653)
                     /gene="lepB"
                     /locus_tag="ACG84X_000315"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFP9126223.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25805..26032)
                     /locus_tag="ACG84X_000316"
     CDS             complement(25805..26032)
                     /locus_tag="ACG84X_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFP9126224.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26029..26547)
                     /gene="msrA"
                     /locus_tag="ACG84X_000317"
     CDS             complement(26029..26547)
                     /gene="msrA"
                     /locus_tag="ACG84X_000317"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFP9126225.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(26567..27280)
                     /locus_tag="ACG84X_000318"
     CDS             complement(26567..27280)
                     /locus_tag="ACG84X_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFP9126226.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27283..28179)
                     /locus_tag="ACG84X_000319"
     CDS             complement(27283..28179)
                     /locus_tag="ACG84X_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFP9126227.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28337..29179)
                     /locus_tag="ACG84X_000320"
     CDS             complement(28337..29179)
                     /locus_tag="ACG84X_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFP9126228.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29311..29964
                     /locus_tag="ACG84X_000321"
     CDS             29311..29964
                     /locus_tag="ACG84X_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFP9126229.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30027..30554)
                     /locus_tag="ACG84X_000322"
     CDS             complement(30027..30554)
                     /locus_tag="ACG84X_000322"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFP9126230.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(30574..31521)
                     /locus_tag="ACG84X_000323"
     CDS             complement(30574..31521)
                     /locus_tag="ACG84X_000323"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFP9126231.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(31533..33416)
                     /locus_tag="ACG84X_000324"
     CDS             complement(31533..33416)
                     /locus_tag="ACG84X_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFP9126232.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            complement(33579..35657)
                     /locus_tag="ACG84X_000325"
     CDS             complement(33579..35657)
                     /locus_tag="ACG84X_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFP9126233.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(35670..35945)
                     /locus_tag="ACG84X_000326"
     CDS             complement(35670..35945)
                     /locus_tag="ACG84X_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126234.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(36307..36762)
                     /locus_tag="ACG84X_000327"
     CDS             complement(36307..36762)
                     /locus_tag="ACG84X_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126235.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(36916..38124)
                     /locus_tag="ACG84X_000328"
     CDS             complement(36916..38124)
                     /locus_tag="ACG84X_000328"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFP9126236.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(38236..38568)
                     /locus_tag="ACG84X_000329"
     CDS             complement(38236..38568)
                     /locus_tag="ACG84X_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFP9126237.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            38716..39591
                     /locus_tag="ACG84X_000330"
     CDS             38716..39591
                     /locus_tag="ACG84X_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9126238.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(39673..40254)
                     /locus_tag="ACG84X_000331"
     CDS             complement(39673..40254)
                     /locus_tag="ACG84X_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFP9126239.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(40260..41519)
                     /locus_tag="ACG84X_000332"
     CDS             complement(40260..41519)
                     /locus_tag="ACG84X_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFP9126240.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(41521..42567)
                     /locus_tag="ACG84X_000333"
     CDS             complement(41521..42567)
                     /locus_tag="ACG84X_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126241.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(42802..43077)
                     /locus_tag="ACG84X_000334"
     CDS             complement(42802..43077)
                     /locus_tag="ACG84X_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFP9126242.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(43320..44630)
                     /gene="der"
                     /locus_tag="ACG84X_000335"
     CDS             complement(43320..44630)
                     /gene="der"
                     /locus_tag="ACG84X_000335"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFP9126243.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(44812..46041)
                     /gene="rpsA"
                     /locus_tag="ACG84X_000336"
     CDS             complement(44812..46041)
                     /gene="rpsA"
                     /locus_tag="ACG84X_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFP9126244.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(46176..46856)
                     /gene="cmk"
                     /locus_tag="ACG84X_000337"
     CDS             complement(46176..46856)
                     /gene="cmk"
                     /locus_tag="ACG84X_000337"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFP9126245.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(46905..47540)
                     /locus_tag="ACG84X_000338"
     CDS             complement(46905..47540)
                     /locus_tag="ACG84X_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFP9126246.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(47606..49009)
                     /locus_tag="ACG84X_000339"
     CDS             complement(47606..49009)
                     /locus_tag="ACG84X_000339"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFP9126247.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(48996..50027)
                     /locus_tag="ACG84X_000340"
     CDS             complement(48996..50027)
                     /locus_tag="ACG84X_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126248.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            50058..50279
                     /locus_tag="ACG84X_000341"
     CDS             50058..50279
                     /locus_tag="ACG84X_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFP9126249.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(50444..51181)
                     /locus_tag="ACG84X_000342"
     CDS             complement(50444..51181)
                     /locus_tag="ACG84X_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HFP9126250.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(51334..52674)
                     /locus_tag="ACG84X_000343"
     CDS             complement(51334..52674)
                     /locus_tag="ACG84X_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFP9126251.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(52911..54434)
                     /locus_tag="ACG84X_000344"
     CDS             complement(52911..54434)
                     /locus_tag="ACG84X_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFP9126252.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(54812..55423)
                     /locus_tag="ACG84X_000345"
     CDS             complement(54812..55423)
                     /locus_tag="ACG84X_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFP9126253.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(55546..55671)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(55753..56469)
                     /locus_tag="ACG84X_000346"
     CDS             complement(55753..56469)
                     /locus_tag="ACG84X_000346"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFP9126254.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(56475..57044)
                     /gene="scpB"
                     /locus_tag="ACG84X_000347"
     CDS             complement(56475..57044)
                     /gene="scpB"
                     /locus_tag="ACG84X_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFP9126255.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(57028..57798)
                     /locus_tag="ACG84X_000348"
     CDS             complement(57028..57798)
                     /locus_tag="ACG84X_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFP9126256.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(57795..58166)
                     /locus_tag="ACG84X_000349"
     CDS             complement(57795..58166)
                     /locus_tag="ACG84X_000349"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9126257.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(58185..59072)
                     /gene="xerD"
                     /locus_tag="ACG84X_000350"
     CDS             complement(58185..59072)
                     /gene="xerD"
                     /locus_tag="ACG84X_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFP9126258.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(59168..59641)
                     /locus_tag="ACG84X_000351"
     CDS             complement(59168..59641)
                     /locus_tag="ACG84X_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFP9126259.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(59746..60609)
                     /locus_tag="ACG84X_000352"
     CDS             complement(59746..60609)
                     /locus_tag="ACG84X_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFP9126260.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(60805..62904)
                     /locus_tag="ACG84X_000353"
     CDS             complement(60805..62904)
                     /locus_tag="ACG84X_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFP9126261.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(63124..64233)
                     /gene="rpoD"
                     /locus_tag="ACG84X_000354"
     CDS             complement(63124..64233)
                     /gene="rpoD"
                     /locus_tag="ACG84X_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFP9126262.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(64257..66098)
                     /gene="dnaG"
                     /locus_tag="ACG84X_000355"
     CDS             complement(64257..66098)
                     /gene="dnaG"
                     /locus_tag="ACG84X_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFP9126263.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVRNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(66280..68595)
                     /locus_tag="ACG84X_000356"
     CDS             complement(66280..68595)
                     /locus_tag="ACG84X_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFP9126264.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(68780..69640)
                     /locus_tag="ACG84X_000357"
     CDS             complement(68780..69640)
                     /locus_tag="ACG84X_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFP9126265.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(69699..70331)
                     /locus_tag="ACG84X_000358"
                     /pseudo
     CDS             complement(69699..70331)
                     /locus_tag="ACG84X_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            70498..71259
                     /locus_tag="ACG84X_000359"
     CDS             70498..71259
                     /locus_tag="ACG84X_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9126266.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            71285..73876
                     /gene="mprF"
                     /locus_tag="ACG84X_000360"
     CDS             71285..73876
                     /gene="mprF"
                     /locus_tag="ACG84X_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFP9126267.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(74064..75251)
                     /gene="tuf"
                     /locus_tag="ACG84X_000361"
     CDS             complement(74064..75251)
                     /gene="tuf"
                     /locus_tag="ACG84X_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFP9126268.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            75619..75975
                     /locus_tag="ACG84X_000362"
     CDS             75619..75975
                     /locus_tag="ACG84X_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFP9126269.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT        20748 a        16020 c        13049 g        26188 t
ORIGIN      
        1 agatattatg gaaattcaac gtagaaccac taatttttta catttaggct ctttttttgc
       61 aactttgacg atcttatttt ttctatgtta ttcatacctt aagacctcac atgcgccttc
      121 tagtgcatta ggctggttgc ttttggatca ttctgatatc acagaagccg aagaaaatcc
      181 gttttttttg attttgtctt ctctttgcgg cttactgttt tctgtttatt tcggtgccta
      241 tttttttcat cgacatcctg gtacgttaaa cgaagcttca agcgtattga ttgcatttaa
      301 aacgttttct tttttagcaa ttctttttta ttcgtttaat cacaatacgc ttttcttctt
      361 tatcatgaat ggtttagtcg tgattttatc catttttact tattttattt tttcactcat
      421 ttttagccaa ttgaaatgtc cgctcttctt tcgattagtt cctgtcacct gttttattta
      481 cagcttgttt tccttttttg tccttgcttt aatgccactg accaaccctt cgacgatcca
      541 agtcgcagga aatctgttgg atatgctctt catcgtcagt ctaggtgtat ttatgtggca
      601 aagaaaaaac aaacaaaata aaaagcattt tgaagcctga ctattacgac ttcataaatg
      661 cttttttagt tttaaacact tcaatctaaa agaataaccc aagattggat aaattattaa
      721 tgactcgcca ttcgtttctt agtgattctg gattatcaaa tggacttcct aatctaatca
      781 gctagttctt cccataaaat gccatacttg actgaatcat aatattgatt atttaaaaat
      841 ctaacttttc ttatcactac ttcctttgtc attccacatt tctcaccatt tttttgcatt
      901 cctttgtttc cagaccatgt agtgaatcta ataggtggta gataggcaaa atactcaaat
      961 aattctttta accataaagg aagagaaagg ctcctcctgc aagagtcagt ataatttttg
     1021 cttactgctc tcttaggttt tactcactaa aactgttcca tattctttga tataagaaaa
     1081 tgcatgcggt ataaatttct tgctcagctc agaaaagatt tgtcgtttaa gaaaggctat
     1141 ttcctccatt gtcaatgaag gatccaatgt tggtaattca atctcaaaat tgtttttttc
     1201 gacaataggt aattctaatg tgaatgattc ttcttccttt atagtattcg tcacaagtag
     1261 agactgatgg aaaatactag gccggcgatt tttatattta ttcttacgta tcctgtcaac
     1321 gataacttct atttgatcaa aaaagtacga ttcatttacg tctccaataa gttcggctaa
     1381 ttctttgaat gccttcgtta caggaagctg attcttctgt acaaaaaagt aattagccaa
     1441 agtaagcggg aagtgttcta tagaggaaag tgtgataaaa cggtacttct catttcctgc
     1501 agttgtcctc agcaattctg tctctcggct gtttcttact ccataaaaat acgcttcttt
     1561 ccgttcatct tcgaaacaat acgcccaaat aacttctccc atcgctaatt tttgttcatc
     1621 aacagagagt ctcttcaatt gttcagctat ggtttcagca gccgaagtgg cttgttgcaa
     1681 gtaatcttta ggatcaaata ttggaaagtt caaatgatat cttcgttctt ccctcttgat
     1741 taatcctgca tcgatcaata aatcaagaaa atgggaaaat ttattttgcg aaaattcttt
     1801 tttcaattct cttagaatcg tttcttgttc tcgatgttca tatagataat cggtcaatga
     1861 agaaaaaagc ggatcatcgg tcagtttttg ataaaagttt tccttatttt ttgaataata
     1921 gttcatatat gttctctttt ctatccgttt tattttactt aaaaggcttt tacgtaaaaa
     1981 ggaggaagaa caagagtcat aattgactgt tattctcctc catttcttcg gcctttagta
     2041 tgttctatgt ttctttttat atcaatcgct tatccattca ttttgaatgc ttcatactac
     2101 catttgatta gctaaataca gccgtcaatt gaggtacgac ttgtttttta cgtgaaacga
     2161 cacctttaag caaagcacgg ttgttggtca aagttgtttg gaaagcttct tctacttttt
     2221 cttttccttt accagcaaca agtaattctg aatcactgtc taagatgttt gtgacaacta
     2281 atacgaacag atcgtagcca tttgctttca tttcatcttc cattgctgct tctagctctg
     2341 cttgtcgatc catcacttca ttaaggtcca ctgtattgac ttgagcgata cgaacgttgg
     2401 aactgcccat tgggaaactt tttgcatcca aatcaagaag aaccgcagct gatttatcac
     2461 ttagatttgt tcctgctttc aacatttcaa gtccataagt gtttagatcg acttcagcga
     2521 ttgctgcaag ttcttttgca gctgcttcat cttcaggcgt acatgttggt gatttgaaca
     2581 acaatgtatc tgaaatgata gctgagagca tgattcctgc gatttcttta ggaattgtta
     2641 cttggttttc tttatatagt tttaaaataa tcgtacttgt acatccaact ggttctgcac
     2701 gatagtacaa tggattagct gtttcaaagt ttgcaatacg atggtggtct actacagcta
     2761 aaatatttac ttcgctgata tctgaaatac tttgttggaa ttcattatga tccacaagca
     2821 tgacatctgc attttctgct ttagctgact ctactactcg tggtgcagat agctgaaagt
     2881 ggtctaatgc gtattgtgtt tcttcattag gtgtacctag agcaactgct tctgtttctt
     2941 tacctaattc attttgcaag tgtgaaaacg caatggctgc cccgattgca tctgtatctg
     3001 gattttggtg accaaaaact aaaatttttg acatgtcatt cgctcctttg tgatttctcc
     3061 tatttaataa tagcaaaaaa acggaaagaa gcaatactta tcttctttcc gatgcgacct
     3121 atcgcgttaa atattttgta tactcttctg tatgaagcaa tcgtttagca ttttcgacac
     3181 gttcttttgt aggtggttcg atcccttcta atggatattt caaaccaagt gtttcccact
     3241 tgtattttcc catcgtatga taaggaagaa tctctactct gtctacattt gacaaggttt
     3301 gaataaagtt gtctagtcgg atcaaatatt catcataatc acttcgctca ggaactagta
     3361 catggcgaat ccaaaccggt ttgttgattt ttgacaaata ttgagccatt tctaaaatat
     3421 tttcattgtc ccaatgcgtt agttttttat gctcttcatt atcgatgtgt ttgatgtcaa
     3481 ataacagtaa atctgtatac ttcatcaatt cttgaaaacg tgaaaagaaa ggttcttcat
     3541 acgtaaaagg ttttccgcat gtatccaatg tagtatgcat cttccgctct tttgcttttt
     3601 taaatagttc gatcaaaaaa tcgatctgca atagaggttc tccaccacta acagtaatac
     3661 cacctttatc tccccagtaa ggtctgaagc gttctgcttt atctaaaagt tcatctgctg
     3721 tgtattcttt ccctccgcca atattccaag tatctggatt gtgacaaaat tggcaacgca
     3781 tgcggcatcc ttgcataaac acgacaaagc gcagtccagg tccgtctact gaaccgaaag
     3841 tttcgataga atgaacatag ccgattgttt tttcttccat ttaagttcac atcttttctt
     3901 tgatttcatt ttaagtacaa gttagctgtc gaagcgaagc tttctgaaca aaatttttcg
     3961 caattgccgc ttcgttatgt gtaaaattta cagggacgga acatacaagt cctgcccctg
     4021 taaatcgttt ctttcaaata agcatactga ttattcgatt ttgatgcgat ggctattcaa
     4081 cgtcctttcg acgctaagtc gaaaaacttt tttcacgaac tttttacatt ctgtcgtgtg
     4141 aagttctcat caagacatct aattgttgtt ctcttgtcaa gtcacggaat ttaactgcat
     4201 aaccagatac ccggatcgtc aagttcggat atttcattgg attttccatt gcatcacgca
     4261 ataaatcatt actgaataca ttgacattca aatgataagc tccttttgag aagtatccat
     4321 ctaagacatt acgcaagttt tcgattcttg tatcttgttc ttttccaaga cctgaaggat
     4381 tgattgtttg ggtatttgaa attccatcca atgcacagcc gtaattcatt ttagctgttg
     4441 agttcaggct agctaataac ccactttgtt ccgcattgta acttggattt gctcctggcg
     4501 caagtggttt tccagcttca cggccatcag gagtatttcc tgtattttta ccgtaaacaa
     4561 catttgaagt aatcgtcaat aatgaagttg ttggttttga gttgcggtaa gttttatgac
     4621 gtttgatttg tcccatgaag tattccaaga tccatgaaac taattcatct gcacggtcat
     4681 catcatttcc gtatttaggg aagtcgccat ccacttcaaa atcaactgct attccttttt
     4741 cattacggat tgcttttact tttgcatatt tgatcgctga caagctgtct gccgcatgag
     4801 agatcccagc aatacctgta gcaaatgtgc gttgcaagtc agaatccatc aaagccagct
     4861 gagctgcttc ataagaatat ttatcatgca tataatgaat gatgttcaac gtattgacat
     4921 atagttctgc taaccaatcc atcatattca tgaagttatg tttcacttct tcaaagtcta
     4981 gtatttctga tgtgattgga cgatattctg gtccaacttg ggcgccagtc acttcatcga
     5041 ctccgccatt gatggcatat aatagtgttt tagccaagtt agcacgagcg ccaaagaatt
     5101 gcatgtcttt tccgacaact gttcctgata cacagcaagc aatcgcacaa tcatcagaac
     5161 cccattgttc acgaagctga ttatcatttt cgaattgaat cgaagaactt tcgatagcga
     5221 ttctgctagc atatgttctg aatccttctg gaaggtgttc agaatacaaa acagtcaagt
     5281 ttggttctgg tgaaggtccc atatttgtta atgtatgaag cagacggaaa tcattctttg
     5341 taactaatga acgaccatct aatcccatac ctgcaatgga taaagtagcc cagataggga
     5401 atcctgagaa taattggtta tattcaggtg tacgcgcgaa tttgaccata cgtaatttca
     5461 ttactaagtg gtcgatcaat tcttgtgctt ctttttctgt gattactcca ttatccaaat
     5521 cacgttggat atagatatca aggaatgctg agatacgtcc gattgacatc gcagcaccat
     5581 tttgtgattt gattgctgct aaatatccga agtatagcca ttggacagct tcttttgcat
     5641 ttgcagctgg tttagaaata tcatagccat atttcgcagc catttctttc atttgcgcta
     5701 atgcacgata ttgttcagtg atttcttcac gtaaacgaat cacttcttca ctcattgtat
     5761 gataaccagt catatcatga tcttttttct tttgttccat caaatagtcg attccataca
     5821 atgccacacg acgatagtca ccgatgatac gtccgcgacc gtaagcgtct ggaagccctg
     5881 taatgatttt gtttttacga gcagcacgca tttcagcagt ataagcgtca aatacacctt
     5941 gattatgtgt tttgcgccag tcagtgaaaa tatgtgtcaa ttcatcgttt ggtgtatagc
     6001 cattgctttt tagcgcattg ttagccatat tgattccgcc gaacggcatg aatgcttgtt
     6061 tcaaaggttt gtctgtctgt agaccgacga ttttttccaa atctttatcc aaatagcctg
     6121 catcgtgtga agtaatagtt gatacgattt ctgtgtccat atcatagaca ccgttacgct
     6181 cgaattggat atcatttaac ttttgcaatt catcccataa tttttctgtt gcttctgttg
     6241 ggccttccaa aaagctgtca tcaccgcgat attcagtgta gttattttga ataaagtctc
     6301 tagtgtctac gccttctttc catttggtac ctttaaatcc attccattgc tccattgtat
     6361 ggacctccta aatttctgtt ttatgtaaca gtttttacgt gattagtata acacagcacc
     6421 ctatctttgc aagggttttc ttgtttttta tttaacaatt tttatgtttt atttacatat
     6481 atttaaatca acgttgacat accaacattt aagcattgtg aacactttca tctttttttg
     6541 caaacgtata aggatttatt aaaaatgaat gaaaaagaga cgccacctgt attaatacag
     6601 atggcgtctc ttcattaaaa tactacaaca gttacgactc gatgaaaatc tcaggagcat
     6661 cgataacttc gatgacttct ccaccttttt tctcatccat cgcaaatgat ccattcgatg
     6721 ttcgatcacc tatagggaaa tcagttgggt caatcgttaa ctgctgccct ttttgattca
     6781 tcaaggttat ttcttttgat cttccttccg acatatagat aatacggtgc ggattttttt
     6841 tcagctcacg catgaccgtc actccccgct tcgcacgtga agtttggctg atttcttgag
     6901 caagcatgcg tttaacagct cctcgctgag taacgattac gatcggcgta tcaccttctg
     6961 ctaacacaag cagcccgttg ataatcctat ctccatcttt caaattcata gacttcactc
     7021 cagctgcctt tgctccaaca acgggaacat ctgttaaagg atagcgcaaa cccattcctt
     7081 gatgcgttac taagaaaaca tctaagcctg gctgatcttc tttcagatac acagcaatca
     7141 gttcatcttc ttccgccttt agcttcatac agctgagcgg acggctctta taggtgcgcc
     7201 atggttcgaa ctctgtcatt cgtgtttgct tgatcaatcc attcttgctg atgaatacaa
     7261 atgttttctc tgcttgaatt ttttgatatg ggaaaacagc taaaatcgat tcgtctacag
     7321 acagattgga gattgtttga gaaatgtgct caccagcatc tttccatttc aaatcgggta
     7381 gttcatggac agggcggtag atcacatttg ctttatttgt gatcagaaga acatggtcca
     7441 atgtactcaa ttcacctgag tatagcaagt agtcgccttc tcgcatcccg atttcttctg
     7501 gtttggaagc actataagaa cgaaggcttg ttcgcttcac atagccttct cgcgtcacac
     7561 tgacaattac gtcttcttgt gccactaaga cttgcgtatc aattttgatt tcttcgattt
     7621 cgtcttcgat tgtcgttaga cgagcggaag aataattttt tttcacttct cgcaattctt
     7681 ttttcataac agagaaaagc tctttgtcat ttgaaaggat tttattcaac tctgtgattt
     7741 gcgcaatcaa gctttcggat tccttttgaa gctctgtgat atccgtgttc gtcaaacggt
     7801 ataattgcaa tgtgacaatt gcttctgctt gttcttctgt aaattgaaag acgtcgacta
     7861 aattcttttt ggcgtctttt ttgtctttac tttcacgaat cgttgcgatt acttcatcca
     7921 gaatcgataa agctttcatc aatccttcta cgatatgctg tcttttttga gctttggcta
     7981 aatcgaattg actacgtttt gttatgactt gctttcgatg ctcgatataa cttcttaaaa
     8041 tgtctttcag tccaacttga tgcggagtca tatggtcgat agcgaccata ttgaaattgt
     8101 aattgatctg tagctcagtg tttttgaaca aataattcaa aattccttga gcattggcgt
     8161 cttttttcaa ttcgacgaca atttgcagac ctgttctatc actttcatct cgtacttcag
     8221 ctattccatc gattttctta ttcaaacgga tctcatccat ttttttcacc aaggtcgctt
     8281 tatttacttc atatgggatt tctgtgatca cgatttgctg tttattaccc ttcattgcct
     8341 ctatctttgt tttcgaacga agaataactt ttcctcgtcc tgtttcataa gcttttttga
     8401 tttcatcttt tccttgcaag atccctcctg ttggaaagtc aggtccagga atatattcca
     8461 tcaatttttc aaggctcgct tgtggatgat cgatcatata gattgtgcca tcgatcactt
     8521 cagctaagtt atgagtcggg atttctgttg catatccagc agatatacct gtcgatccat
     8581 tgacgagaag gtttgggtat cgagctggaa ggactgttgg ttctttttct gtatcatcaa
     8641 aattccacac gagatcgact gtttctttct cgatatctgc tagcatctct ccacttaact
     8701 tggataatct ggcttcagta taacgcatcg cagcaggtgg atcaccgtcc atactcccgt
     8761 tattcccgtg catttcgatc agtacttccc gcaacttcca gtcttggctc atgcggacca
     8821 tcgcttcata aatactgatg tcaccatgag gatgataatt ccccatgata tttccgacag
     8881 attttgctga tttacggaat cctttgtcat acgtattgcc atctttgttc atggcaaata
     8941 atatccggcg ttgcactggc ttcaatccat cacggatatc aggcagtgca cgttcttgga
     9001 taatatattt ggaataacgt ccgaagcggt cacccatcac ttcttctaaa gttaattctt
     9061 gtacttcttg tcgattttcc atcaggtgac ctcctattct acttcaaata actgattgtt
     9121 ttcattttta tctgctcgtt cttcatctaa taaatcatta gaaactgaag gagagatttc
     9181 agtatcctct tttttatcta agatactgcc atcttcttcg agcgtaaatt gcacgtgatt
     9241 ttcgatccat tttcttcgag gttctacttt gtcacccatc agtgtggtta ctcgacgttc
     9301 agcttgcgca gcatcatcga tacggacgcg gatcaacgta cgggaagtcg gatccatcgt
     9361 tgtttcccac aattgttccg cattcatctc tccaagtcct ttatatcgct gcagcatata
     9421 tcctttgccg acttttttaa tcattgctgc caattcgtca tctgtccacg catattcaat
     9481 gacttgcttc tttccttgtc ctttggatac tttatataaa ggcggtaacg cgatatatac
     9541 tttcccagct tcaatcagcg gtttcatata acgataaaag aaagtaagca gtaatacttg
     9601 aatatgggcg ccgtctgtat ccgcatcggt catgatgatt actttgtcgt aattacagtc
     9661 ttcgatagaa aactcaggac cgactcctgc accaatcgta tagatcatcg tattgatttc
     9721 ttcatttttc aagatatctt gcattttagc tttttcggta ttgatgactt ttcctcgtaa
     9781 aggtagaatt gcttggaact ttctgtctct tccttgttta gcagatccgc cagcagaatc
     9841 cccttcgact aaatacaatt catttttctt agggtttcgg gattgtgcgg gtgtcaattt
     9901 tcctgaaaga agagattcgc cttttttacg cttcttccca tttcggcttt cttctctggc
     9961 tttacgtgct gcttctctcg cttctctggc tttgattgct ttacggacca acatctggct
    10021 catttcgcta ttttcctgca aataaaagcc catttgttca ctgatgacgt tatctactac
    10081 ggtacgagca actggcgtac caagtttttc ttttgtttgc ccttcaaatt gcagaagatt
    10141 ttcaggtaca cggatagaaa gtacagcagc taacccttct ctgaaatcac taccttccag
    10201 attcttgtcc cgttctttca gcaaaccaac ttttctcgca tattcattat aagatttcgt
    10261 catcgccgct ttcataccag cttcatgggt tcccccatct tttgtccgaa cgttattgac
    10321 aaaagataaa acattttctg aataaccgtc attgtattga taagcgacct ctacttcgat
    10381 accttctttt tctcctgaaa aataaacaac tggtgtcaat gtatcttttt cttcattcag
    10441 ataatcaaca aattctttga ttccttcttc gtaatgaaaa atttccttga ctggttcttc
    10501 tccacgaaga tcagaaagag agattttaac gccttttaga agaaaggcag attctcttaa
    10561 ccgttcggct aaaatttcat atgaaaattt cgttgtactg aatattgtat catctggtaa
    10621 aaaatggaca gtcgtcccgt ttgctttttt tgtttttcct atctttttca aagtaccgtc
    10681 aggtttaccg ccgtttttaa atttctgctg atactctacg ccatctctaa cgatcgttac
    10741 aattagccat ttcgataagg catttaccac actggctcct acaccgtgca gtccaccaga
    10801 agttttgtac cctccttgac caaactttcc gccagcatgc agcacagtaa aaatcacttc
    10861 aactgttggt attccggaag catgcattcc tacaggcatc ccacgtccgc tatctgcaac
    10921 agttatacta ttgtcttcat ggatggtcac atcaatctca ctgccataac ctgataatgc
    10981 ttcgtcaact gcattatcga cgatttcata gactaaatga tgcaagcctc ggctgtcagt
    11041 ggatccaatg tacatccctg gtctttttct aactgcctct aatccttcca atacttggat
    11101 ggacgagtca ttgtattcgt tgtttacttt ttttgccaag gcaaacgctc cttcaataat
    11161 actttgcggc aaaaccgcac cacgattatc atactagaaa aggtcgtgaa aaaaaagagg
    11221 gtagacgaga aatcaatttt aattatctcc taaccgcttt ttcgacattc ccctctatcg
    11281 atcatctctt ctttgtggtc atttttattt ttggttttct ttcaacttac caagttcaat
    11341 cttaatacaa cgatccatta cgatatctgt acgtcctgct tttcttagca tctcagctgc
    11401 ttctttgttt tcaatcccta attgtgccca gaacacttta gcatcagttt tcaaaaaatc
    11461 acctgctatt tcaggtaaaa attcactccg tctaaataca tctacgatat cgattggatc
    11521 atcgatttct gtcaaattcg catagacttt ctcgcctaga atttcttcac cagccaataa
    11581 tggatttact ggtatgattt tatatccatt gtcttgcaat acctgtgcaa ccatgtaact
    11641 tgttcgttct ggtttattgc tcaagcctac gacggcaata ttttttgctt cttccaaata
    11701 gttgaaaatc gtttcttgtg ttggattttt tacagacatt tctgccaccc cttgcttttc
    11761 tttttattcc atctattata cttgtatctt tcattttttc aattgttcct gttacctatt
    11821 catgctaaaa taaaggatag ttttcaactt gaaagagggt aaaaaatgaa attgatctta
    11881 ttacttattt tagcatatct tttaggttct attccttccg gtgtctggat tggcaaattg
    11941 tttttcaaaa aagatatccg acaacacggg agcggtaata ctggaacgac caatacattt
    12001 cgtgtattag gcaaaacagc cgggattgtt gtcctgctta tggatatttt aaaaggtaca
    12061 ttggctactt gtttgccgat gatcttccac ctttctggga ttaaccctct ttggtttggg
    12121 gtatgcgcca ttcttggcca tacatttccg atttttgctg ggttcaaagg aggaaaagct
    12181 gttgcgacaa gtgcaggaat gcttttagga tttaatcctg tattttttgt ttattcttgt
    12241 atcatcttta tcgttagttt attttgtaca agtatggtga gtttgagcag tatgatcagt
    12301 gcagtattga tcactttatc tacgatcgtc cttccttatg tagctcctgt gattttggct
    12361 aagcccaatt ggttactgac gatcattgcc tttttagttt cttcctttat cttttatcgg
    12421 cataaagaca atatcaagcg tatcagaaac catactgaaa gtcgaatccc gtttggtttg
    12481 aatagcagca agaaaaaatc ctgatacttt ttcattccaa agagataaaa cgggagtgtg
    12541 acaaatcgat gtcacactcc cttattactt acaggatagc ttttttacac accttggtaa
    12601 acggtgttcc ctgctaactt ctcggtcaca acctcttact tcactgtgat ggaatatttt
    12661 gtcttgaaga tttcatgggc acctagttga ttgatcccta ctttttccat caagtttcca
    12721 ctactgttca ccgtgtcagc gattccgcac cacggttcga tacaaacgaa aggcgcttct
    12781 tttggataag gagaccagat ccctacataa ggcatatctt tatagcttaa agttacgcta
    12841 tgggaagatt tttcacttcg aatggcgtac gcatttagac cccttgtttc aaaaaccaag
    12901 gcatcttgct caaaaagttc acgattcaaa gccagattcg tatttgtctg acctaacgtc
    12961 ttttgatcca tatcgatgaa tgggcctttc aatggtaggc gtaatcttga tttcaatgga
    13021 gaaaatgcca gatagaaatc ttcaaatgac aatccttctt caagaggtac attgaaagca
    13081 ggatgtccac cgatagaaaa gaacatttct ttttcaccgg tatttgccac ttgataatga
    13141 accgtgatgc cgtctcctcc taattcatag ctgatcacta attcaaaatc aaatggatac
    13201 ttttctaatg tctccggcgt actccttaag atgaaactag ccatttcttg tccatgttca
    13261 atgacttcaa aatccatatc ccgagcaaat ccgtgttgcc ccatttgata tgttttccct
    13321 tgataaacat actgatcatc ttttaaacgt ccaacaaaag ggaataaaac cggtgcatgt
    13381 ctgccccaat acgctggatc accttgccag atatactcta aaccatgttc ttttgatttc
    13441 agactgatca attccgcacc gtgttcagcg atttcggcga tcagctggtc attttgaata
    13501 ataacagtca ttgccattcc tccaacttcg acttactttt taaaatggga aggctggaac
    13561 aaacatttct atctgcccca gtccccttac ttctaataac tgtgttttgc taactcgtct
    13621 ttaaaacggg aattcaatac ttttaaataa gttcccttca tgcctaacga acgagattca
    13681 atgattccag ctgattccaa ttttcgtaaa gcattgacga tcacagaacg agtgatgccg
    13741 atactatcgg caatattaga agcagtcaga cgaccttcat ctccatccaa tgcttcaaag
    13801 atagcttgta cagccttcaa ttcgctataa gataatgtgt tgattgccat ttggacagcc
    13861 gttgcactcc gtacatctgc ttcgatgctt cgagacttct gataaaggat ctgcataccg
    13921 acaaccgtag ctccatattc tgctaagact agatcgtcat ctgcaaacga ttgttccata
    13981 cgagataaga taatcgtacc caaacgttcg ccagctccaa agatcggaac gacagtcgtc
    14041 agaccaaatg gatatttctc tcttgactct accggaaatg cagtaatatc actagtaatt
    14101 gggatattag cttcagtttt catcaactgt gccactgtat cagtataaga ttcaggaaat
    14161 tgtttctcaa caaacattgt tttgattcgt tcattgttca catcgtgacg ttcattataa
    14221 cctagtaata ctccgtcact tcctatgata taggtgttgc tgtcaagaat accacctagt
    14281 gtgacagcca ttttatcgta aggcaaatct gcttgcatgt caaaagtatt cttttgctgc
    14341 aaaagtgtgt ttatcttgcg ggttttcgtt agcaagtctg tcattgtcgt cctccgattt
    14401 tttataaaat atagcgactt aaatcttcat ttgccgcaat tgagccaagt ttgtcatcca
    14461 catatgcttc tgtgatcgtt atttctccca tttgcatatc tggtgcttca aataatagat
    14521 cttctagtag tttttccaaa atggtatgca gtctgcgtgc gccgatatta tctgtgtcac
    14581 ggttgacatc gaaagcgatt tgagcgatcc gttcaattgc ttcttttgta aacgtaactg
    14641 acacattttc tgtaccgatc aacgcgacgt attgttttac taaagcatta tttggttcgg
    14701 tcagaatctt cacaaaatct tcagctgtca aatcatctaa ttctacccgt atcgggaagc
    14761 gtccttgaag ttctggaatt agatcacttg gtttagacaa atggaaagct cctgaagcaa
    14821 tgaataggac gtgatctgtt tggatgatcc cgtattttgt gtttacttgt gaaccttcga
    14881 caattggcaa tatgtctctt tggacgcctt ctctggatac ttctccagat tgctgtgatt
    14941 tagaagtgat cttatcgatt tcatcgataa aaataattcc actttcttcc gctaatttga
    15001 ttgcctcact atggatatca gcatccttga ctaattttgc tgattcttcc ttgatcaata
    15061 actctaaagc ttctttgact gttaccgtcc gttccacttt tttcttcggt gtcaaagcac
    15121 ctagagtttc atttaggtcg atccccattt gctccaatcc attgttcatc attggtgcag
    15181 gtttcttttg gtcttcaact tcaatggtta cttcacgact atccagtaaa cccttttgta
    15241 gttgttccaa gactgtacgg cgattgattc gaatatcttc tgtcacttct tcttgcggtt
    15301 cagcggtatt ttgctgacta gcattaaaaa gattcatcat ttgttcaaat tgattagtgg
    15361 attgtttctg ttcttttttg ataccaggta ccaagatttt taccaaacgt ttttctgcat
    15421 tttttttagc acttgtgtat acacggctgt actgctcttt ttctacgatt tggatcgcat
    15481 tttctactaa atcccgaacc attgattcta catctcttcc gacataaccg acttcagtaa
    15541 attttgttgc ttcgactttg acaaatggtg cattgacgat ttttgccaaa cgtcgtgcga
    15601 tttctgtttt accgacccct gtaggtccga tcatcagcat attttttggt gtaatatctt
    15661 gttgcatttt ttcatctaac tgcaaacggc gatagcggtt acgcaaagca acggcaacag
    15721 atttttttgc tgcgtgctgt cctacgatat attcatctaa ttcacttacg atttgtcttg
    15781 gtgtttgttt taattcatac atatctactc acctcttaca gttcttctac gataatatta
    15841 tgattagtaa agatacagat atctgcggca atatttaacg cattttctgc aatttctttc
    15901 gcactcatgt cgttttgagc atagtttttc attgctcggg ctgcagccaa cgcaaaattc
    15961 cctcctgatc cgatagctaa gataccatca tctggtgtga taacttctcc tgtacctgaa
    16021 acaagaagca tttctttatc attcattacg atcagcatcg cttcaagttt ttgcatagat
    16081 tgctgtgtcc gccattcttg agctaattcg acagctgcgc gttgtagatt cccgttatat
    16141 tcgtttagtt tgccttcaaa tttttcttct aaagtaaacg catctgcaac acttccggcg
    16201 aaacctacaa caacttctcc attgtagata cgtcgtactt tctttgcagt gcctttcatg
    16261 acaacagatt cacccattgt tacttggcca tctccagcca tagcaaattt cccgtctttt
    16321 tcgacggcac agatagtggt tgaatgaaat ggtgattcga ccatgtttgt ttcctcctaa
    16381 atttgttctt ttccttattt ttacgctctt ggatggaaag aacgatagtt tttttgtaaa
    16441 ctttcttttg ttacatgggc atagatctgg gtagtcgata aattggcatg tcctagcaat
    16501 tcttggactg tccgcaaatc tgccccatta tttaataaat gagtagcaaa tgtatggcgc
    16561 agcatgtgag gatggatatc actatccaaa ctgctttttt tgatcatttg attcaagaca
    16621 tattcaattc cagtaggcgt gattggtttt ccatgatgat tcacaaaaac gatatcatgc
    16681 tcttcgtgat attttgtcat caatacctgg cggccttccc tgaaatattc ttgcagagca
    16741 tcttgagcaa aagaacctag aggagcatat ctctctttgt tccctttacc atggatcaac
    16801 atgacctctg aatcaaaatc aatgtctgat accgacaaac tgctacactc acttaaacgg
    16861 atgcctgacc cgtaaaggac ttccagtaaa gcgcggttcc tcaaatccaa aggactatct
    16921 cctgctacgc tgtcaaaaag tgcttgcatt tcattttcat aaaaaaaacg tggcagtctc
    16981 aaatttttct ttttgagatg aacgtaagaa aatggatttt cttttatcac ttcttctttg
    17041 agaagatact gataaaacga acgtaggctg gctatcttgc gactgataga atttctgcta
    17101 tagctaggac gatgatcagc taatgcactc aaatagacac gaaccgtaaa atattccgcc
    17161 ttcagcagat cagcgtctcc agattcctcc aaaaaatgtt tgaaatggag aatgtcttct
    17221 tcatatgctt ctttcgtttt ttctgaatat cctctttcga caatcaaata acgcaaaaat
    17281 ttttgttccc acgtggcttc tgtcattttc tcaccttcct tttgtcccag agaataattt
    17341 agcacagcgt ttataaaaag acaaataaat tgtcagaatt taaccaatat ttctaagttt
    17401 gttcacaatt ggcgcaattc ctcacatttt gtttgagaaa ttcttaagaa aaacgcaaga
    17461 aaaagagcga gactatccgt ctcaccctct tcatggagtt tccttactca tttgggattg
    17521 cagttttttc taattctgtt tttattgcct cattagcttt taaagctcgt tgtgcaattg
    17581 cttcatatct tgcttttttg tctcgaatgc gctctggcag ttcaggaaac agaccatagt
    17641 tggcattcat cggttggaaa tgttttcctt ccgcatgagt aatgtagtaa gccatacttc
    17701 caatagctgt ttcttgtgga aactcgactg gttccatttc ttttgctaag cgtgcggcgt
    17761 tgattccagc aagtagtccg ctcgctgcac tttcaacata gccttctaca ccagtcatct
    17821 gacctgcaaa gaacagatct tcgcgtttcg ttgattggta agtcggtttc agcaattctg
    17881 gcgaattcat aaagctgttt cggtgcatca caccatagcg aacgaattca gcattttcta
    17941 acccaggaat catccggaaa acacgttttt gctcgcccca tttcaagtga gtctgaaagc
    18001 ccacgatgtt gtataaagaa gctgcagcat tgtcttgacg cagctggata acagcataag
    18061 gacgtttgcc agttttagga tcttccaatc caactggttt cataggtccg aaaagcatcg
    18121 ttttgaatcc tcgctgtgcc attacttcaa ttggcataca tccttcaaaa tatttttctt
    18181 tctcaaaaga tttaagttct gccacttcgg cattgattag tgcctcatgg aaagctttga
    18241 attcctcttc tgtcatcgga cagttcaagt aagctgcttc tcctttgtca tagcgggact
    18301 tcaaatatac tttatccata tcgatcgtag ctttgtctac gattggtgca gctgcatcat
    18361 agaaataaaa accatctgaa ccattgaatg ctttgatgct ttctgctaat ggatgagaag
    18421 tcaaaggtcc tgttgctact acggtgattc cttccggtat ttcagtaatt tcttcgttta
    18481 tcactgttac taatggatgc tctttgactt ttcgggtaat tgtttcagaa aaagaatcgc
    18541 ggtcaacagc taaggcacca ccagctggca ctgctgtttc atctgccgaa gtgattacta
    18601 ccgaattcaa tcggcgcatt tcttctttca ataaccctac tgcattagcc aaactgtttc
    18661 ctcttaatga attggaacat actagttcag caaaattact tgtgtgatgc gcctcagtcg
    18721 atttgactgg acgcatttca tataaacgga cagggactcc tgcttgtgcg atctgccaag
    18781 cagcttcact tccggcaagc cctgctccaa caacatttac cattttcaat gaaagaacct
    18841 cttttctatt atttttggat gtcttcttcg taatctccat ttacacagac tacttgttta
    18901 ccgcctttga ctttcttctc gaccagatat ccgtcacatt ttggacaatt tctgcccact
    18961 ggtttatccc aagaagtgaa ttcacattct gggaaacggg aacaaccata gaatagtctg
    19021 tttttcttag attttcgttc aatgacttgt ccttcatgac atactgggca agtcacaccg
    19081 atttctttta cgattggttt cgtattccga caatcaggaa aattactgca agcataaaac
    19141 ttcccatatt tccctaattt tatcaccatc ggatgtccac agacatcaca atcgaatcct
    19201 gctggttcat ctttgatttg aattttttcg attttttctt ccgcattcgt cagttctttt
    19261 tcaaacggtt tatagaaacg atcaaccact ttgacccacg cttccgtgcc ttcttcaatt
    19321 ttatccaaat ctccttccat ttctgctgtg aaatggatat cgacgatttg agggaagaat
    19381 tcacagatta atgaattgac aatttctcct agttcagtcg gctcaaatct tttttgtgtc
    19441 aattttacat agtagcgtct ttggatcgta tcaagtgttg gtgcataagt ggaaggtcgc
    19501 cctaccccgt tttcttctag tgcacgaatc aacgtagcct cactaaaacg tgctggtggt
    19561 tgagtaaaat gttgttttgg ttcaatatca acagattgga ctacatcgcc ttcttcaagt
    19621 tctggaagaa tattttcttt ctcttctttg ccgtcatctc taccttccac atacacttgc
    19681 atgaatcctt tgaatttgat ttttgaaccg ttcgcaatga agatgacacc attttgttct
    19741 aatgtcactt tcattgtatc taaaatagct ggtgtcatct gactagccac aaaacgtgac
    19801 cagatcaatg tataaagttt caattgatct ttatctaaat attgtttgag ttcatctggt
    19861 gtacgaagca cactcgttgg acgcacagct tcatgggcat cttgtgcgcc ttgagcattt
    19921 ttgatctttc ggtgatcatg tctagaaaat tcttttccat acgtatcttc aataaatgct
    19981 gcggcctctg cttttgctgt atcggcaatc cgggtagaat cagtacgcat gtatgtaatc
    20041 aagccgactg ttccttgttt acccaaagtg attccttcat ataattgctg tgctaccatc
    20101 atggtttttc ttgttcgaaa gtttaactta cgggcagctt cttgttgcag gctacttgta
    20161 gtgaaaggat tcgcagggtt tcttttgcgc tctttctttt ctactttttt aacttcgaag
    20221 tctgttccat caattctagc agtgacttct tttacacttt gtgcatctgg taatttcttt
    20281 ttcttaccgt cgattcccca gaaatttgct ttgaatttct tgcgagcttt tttaaaatta
    20341 ccgtcgatgc tccaatattc ttctggaaca aattctcgga tctctttttc acggtcaata
    20401 ataattttta aagcgacaga ttggacacgt cctgcactta accctttctt gaccttacgc
    20461 cagagaatag gactgatcga ataaccaacg attctgtcta aggtacgacg agcttgctgt
    20521 gcatctacta aatctacatc gatcgttctt ggttccttaa aagctgcttt gactgcgtct
    20581 tttgtgattt cattgaagac cacccgattt ttttctttca gatccaaccc aagtaggtac
    20641 gctaaatgcc aagcaatcgc ttctccttct ctatccgggt cacttgccaa gtaaactttt
    20701 tgagcttttt ttgctgcggc tttcaggctt ttgatgacat cgccttttcc gcgtatagaa
    20761 atataatggg gttcataatt gttttcaaaa tcgataccca ttttactttt cggtaaatct
    20821 cttatatggc caacactggc cattacttta tagtttcgtc caagatattt ctcaattgtc
    20881 ttggcttttg caggtgattc tacaatcact aaatatttat acgccattac tgaatggact
    20941 cctttccatt gtcgtgttcc tactattaaa agaggattca tacaaatcgt agctaatcat
    21001 atccattcag aaaacgtttg tcaagaaaag caaatgaaaa gtatggtgtt attctttaaa
    21061 ttctgccaag atatcttcac ccgaaaccgt gcaaactgca ccgtcttgga tcaaatgatg
    21121 acatccggta gaatgttctg ttaaaatatt tcctggaaca gaaaaaactg ttcttccaag
    21181 atccaatgct tgctgtgctg ttatcagaga gccgcttttt ttcttggctt caaagacaca
    21241 tgttccttta gacaaagctg cgataatccg atttctcatt ggaaaacaat gctttttcgg
    21301 gccggattga ggaggatatt cactcaaaag aagatgatca tttgcaatca cctcttgcaa
    21361 gtcacgattt tcagcaggat agacttgctc tatccctgtt ccaatgactg cgattgtccg
    21421 tccaccatga gagattgctg cttggtgacc gtatgtatct atccctttcg cgcagccact
    21481 gacgatcaca tatccagctt ctatcactgg ttttagtaaa taataaactg tttttttggc
    21541 taaagcagaa gtgtgtcttc caccaacaac gcttaacatg ttacaagaaa gtaaagatag
    21601 atcaccatta taaaacagta caattggcgg ataggtcaag tgaagcagct gagggggata
    21661 tttgggatca aagcaagtga taaacgactg tttcgattgg attttgcccc agttagcgtg
    21721 aatttcctgc caacttttgc gaaacagctc ccggtgtttg gttattttac ctatcttaat
    21781 gatgtcttca aatccgattt ctttataagg atactgcatc atccagttag caagtgccca
    21841 ttttccttga ctactgattc cttttgtata agcaagtttc aataaatttt cttctatttg
    21901 atacatcata aaaccgcctt tcgtctctct ttctaataag atacgtaaaa gcggctgttt
    21961 tttattgtaa atattttttt acaggtgcaa aacttttacg atggattggc gtaattcctt
    22021 gtcgttcaag tccttctaag tgttcctttg ttccataacc tgcattatgc gagaaaccat
    22081 atccaggata aagcacgtca tattctttca tcaattggtc tcgatatact ttagcaatga
    22141 tacttgcagc agcaatcgac acagatcgtg catccccttt gattattttt tcctgctgaa
    22201 taggcaaatc caaggtcatc gcatcgatca acaaatagct tggtacaatg gacaattttt
    22261 ctactgcttg gatcatcgct aatttacttg cttcataaat attcacatca tcgattgtct
    22321 gctgatcaac gatcccgatc ccgattgcca gggctttttc ttgaacttgt tgataaagaa
    22381 gttctcgctt tttctctgat aattgtttgg agtcattcag ccctaatatg atctcatttt
    22441 tcggcaagat aactgcagct gccacgacag gtccagctaa tggtcctctt cctacttcat
    22501 caatgccggc aatccattgg tgaccttgtg cgtacccttg cttttcaaag caaaacattt
    22561 cttcatattt ttccttaatt aatgcttcct ttttcaatcg tcgttcaaaa gaagccagtg
    22621 cttgctgcac gcctttgcgt ggatcatttc ttaatgattc tagtgtagga tcatctattc
    22681 tctgtatgct tttcaatcgt tctttgatac tttggatgga ttcagtcatc acttttttgc
    22741 tccatttctt cgcaacgatc cagtgtgtat cgtccaagtt ttccttgacg aatatcatgc
    22801 acgactaatt cgctgccacg atcatagtct tctttatacc cacgttttgc tgtaatatcc
    22861 atcagtaatt ccggtgccaa tttttcttct tgctcgattg ataaaccata acgatcgctg
    22921 attcttcctg aataatatcg ggcaaaaaag tctaatccgt aaatcgctaa atcatctaaa
    22981 tggacaagct ggtctttgat cgcgcctgtc agcgctagtt ttttgccgat ttcttcatct
    23041 tcaaatttgg gccataaaat ccctggtgtg tctaacaatt ccaactcatt acctaaacga
    23101 agccactgct gaccttttgt tacgccaggc ttatttcctg tctgtgcaat tttcttgcct
    23161 actagtcgat tcatcaacgt agatttccca acatttggaa tacctaagac cattgcccga
    23221 atagcgcgag gcttgatccc ccgagcagca tctcttgccc gtttttcttt caatgcttct
    23281 ttagccgcag gtactagacc tttaattcct ttactttctt gtgccgtgat agctaatgca
    23341 agatggcctt gtttacgaaa atattcttgc cacagctttg tctgttgtgg atctgccaga
    23401 tccgctttat tcaataaaac aaggcgaggt ttttgctgaa tgatctgatc tagcattgga
    23461 ttacgagaag ataaaggtaa tcgtgcgtct accaattcaa atacgatgtc cacatatttc
    23521 attttttcag aaacttctcg tcgggctttt gccatatgtc ccggaaacca ttggatggtc
    23581 attgttctct ccattccttt cataccggaa tattccccgg ctttacttgt ttttttcttt
    23641 ttcaatataa attcactttt ttattataaa gaaattccat ctattagtta agtgaaagtg
    23701 aaccagtcct cattctatca catcttcact tttttgatga tgcaaatttt tattttggtt
    23761 tctatatatg aatctaaatt tttgacagcg tttcctaaat aagagatgat agacgaacaa
    23821 aacagaaagg agacgaaaca aatgaatagt atggtttttg ttaattttcc tgttgctgat
    23881 gtcaatcgtt ccgttgcttt ttatgaaaag ctgggtttta aaaaaaatga agaattttct
    23941 actgaagaag ctggttcaat ggtatgggat gacacttttt ggataatgct tctctctcat
    24001 gatttttata aaaaatttat aaaagataaa gaaatagctg ataataaaaa aacaagtggt
    24061 gctttgattt cgtttagtgt tgaaaatgcg gatgaagtaa aaaaatttgc tcaaattgca
    24121 aaagaaaatg gtggtacttt ccacgaagta gatatgggaa tgcctgaaga agaaatgttt
    24181 tcattagaag tccaagatct agacggaaat acattagaac ccgtatggat gaagatgtaa
    24241 gcagataact aatctgacgt tttttataac aaaaaaacaa aggcggatga tacgataagt
    24301 attctccgcc tctatttttt ttattcgtac aatctctttt ttacagttta taaaagcagt
    24361 cttctcaccc tttttttaat tgttagatgc cagtgtatgt aaatcaccaa tgtgtcatga
    24421 cacattggtg attttatggt atccttttat tattaactga caaaggagag aatattttga
    24481 acactttgat tgcaaaagac gtttttagat tgcccgaaat gaatgcaaga ttgttgtcga
    24541 cctctgctct tttattagcc cttgatgtca tcttatacaa gatagcgatt ggtcctgctt
    24601 attttcaaat cacattcgga tttttaagta tggcgcttat gggttatcta tatggaccga
    24661 tctgggctgg tttgcttgaa atgttgtcga acactttaaa tttcacgata tttggttcag
    24721 gaacgtttca agctgctttt cttatcacgg ctttccttgg tggatttatt aatggcttat
    24781 ttttatatca taaaaagata aacctgcctt ccgtcatcgc tgcccaatta ttgattatga
    24841 tcccagtcag cctttttatc aattcttggc tgatgtctgt tttgtttggt gcagatttca
    24901 aagtaatttt tctaggtaga ttcatcagga atatgatcca aatccctatt caaataatgg
    24961 ttgtttattc atttatcaaa actttagagg ctagaaaagt gtttaaacga gctgtttgat
    25021 tttacgtact aaggtagtaa actgattttg gattaaacaa taaagcgtgc agtctcaaca
    25081 gactgcacgc tttattgttt ctcactggat ccattttatt tcatcaagtg gataatagac
    25141 aaatcttgct ttacctagaa tatcagtttt attgatcgtg ccaaacgaac gactatcttt
    25201 tgaaactctt cgattatctc caagtacaaa ataattatct tccggaagct tggattgtcc
    25261 cgttagctct tgtagtgtaa agtccgtcgt ataggatgca tttgcatgat ctgatttcag
    25321 gtttttagtt agataaggtt ccttaactac tttcccattg atcttcaatt gatcattttg
    25381 gtagctgaca ttttctcctg gaagaccgat tactcgtttg atataaatcg tgccatctgc
    25441 taattgaaaa acaacaatat caaatcgtct gatctccgaa aatttttcca tcacaaccat
    25501 atcaccttgc ttcaacacgt tttccattga attgccttcc actggtaccg ggatgaataa
    25561 aaatccccgc aacatgaacg caaggaatac agaaacaagt aagtatttga atacaagcca
    25621 gaagcgatta atatagcgtt gtttttttgt caatctctat caatccatcc ctcttttttt
    25681 cattctttct ttattataag aaaaatatca aaaaaatgcg actagatagc tgaaataaaa
    25741 ataattcttt caattaggct attggacaaa aaactttttt gatcataaag tacaaaacta
    25801 tctcttatat gtcatgatta ttttctaaat atttttccca tgcttcgtca aagatatcca
    25861 tggacggcaa atagtcgaca ttcagttcca gataattaga aatttcttcg tagctagagc
    25921 tgtgcttagg aaattggatg tctttaccgg cttctgtagc gaaaacagat aaagcatcat
    25981 gtgtgccacc gcctcgcagt gtcattaaat aatgaaaaaa gcttcgattc acccttcgtt
    26041 cctccaattt tcttcgataa aggcagcccg gcgtgcatgg tttcttttaa aattttcagg
    26101 atgcttttta taatactctt gatggtcttc ttctgctaga taaaatggtt gggctggttc
    26161 gatttttgta acgattggct gttcgaaacg tccactttca gctaactgtt tcttactttt
    26221 ttcagcaatg atccgctgtt cttctgtcaa ataaaagatc accgggcgat aattgtcacc
    26281 gcgatcctcg aattgtccga aagcgtcagt tggatcagtt tgctgccagt aaagttctac
    26341 taattgttca tatgaaatca atgttggatc atagataatc tccactgctt ctgtatgtcc
    26401 agtcgtttgg ctttttactt gttcataagt cggatctggt acatgccctc cagtatatcc
    26461 tgacatcact gtatggatac caggaagcgt gtcgaaaggc tggatcatac accagaagca
    26521 gcctcctgca aatattgctc gttccattat gattccccct ctaatactac tcatccgatg
    26581 attttttatt ttcttttgtc ttgctttcag tactgctggt gctagttttg ttggtatttg
    26641 agttgtttga agcatcagag gtatcttttg gcaaatatag actaaaccga atgtcatcat
    26701 ttactaagtc gattttatct gctttaatat acatcccgtt ttgcattcgg aattgatcca
    26761 acctaagcat gatagtcaga tcatctgtat tgacttcgat ccaatctggt aatttatagt
    26821 ttctcttgat catattcatc acatctttga ttggcaaact caatgttccg atagaaagac
    26881 ttctagcttt tagttggaca tttccgtttt ccatcacata cggatcaaaa tataaataga
    26941 aatcgatagg aaaacctagt acttcgaaag taccattgag tagtgcttca ttttccaaat
    27001 aaaatttata ttcaatatca ctatcttttt gatactcact aaggaaaaag ctgatgattt
    27061 gattgacttt ttctttattt gaattgatcg ttaagacagg atctccttgt ctttccgtaa
    27121 gagctggtat ttctgggagt tctggttccc gattagcaaa aatacggctg cctaaaaata
    27181 cggtcgaacc aagtactacc ccaagaagga taaggaaggc gaatttccag taatttgttt
    27241 tctttgtttt gtttgaagat acgtcagatc ttgttttcat gtttattgat catcctcctt
    27301 ctctaaccat tggttttgtg tctcgatcag ctgatctctc actgcatttg ccatcaattg
    27361 ataacctaaa ttatttggat ggaaatgatc ttcttcatag agcacattat ttttgatgcc
    27421 atttagattt tctgtcgtgc tagttgtttg atctgttcct tcttctgtga cacctacttc
    27481 ctgattcaat ccttgataaa gcaaatcatt gattgggata aagtagcagt tcggcatttt
    27541 ttttgtcacc gtttctgttc ctttgttcca attgttaaca attgtctgca tgtcagtgat
    27601 ctcaggaaag ttcaaataaa atggattgta gatgcctaaa atgtaaatag gtgcggtttt
    27661 attgagggat cgaaattctt ccaatagttc tgtgacattt tcctgatagt ttttcagtgg
    27721 ctttttaaag gaattgaccg ttaacccgaa taaattattt tggataactt tcatcaaatc
    27781 attaccgcca acagtcagtg tgataaaatc agctgttttg atattgtttc gaatttcttc
    27841 ttttgttttt actcgcttta agatctggtc acttcgttca ccatttacac catagttttc
    27901 tgtttcaacc gcggtcaaat tataacggtc ttttagatca tttgcgacaa ggggaacgaa
    27961 tcctccttgc ttggtttgat ctcctactcc ttcagtcagc gaatctccga tagctatgta
    28021 gtgaagtttt tcttttttat ttggatcttc tctcacagta gttactggtt tcattagtgg
    28081 gccagctttc ggtatagaag cagctaaacc tgcatagatg atgatcgcaa ttaataatgg
    28141 gaacaaaacg aggatcaaat gtcgtttcgt taatttcatt ttttcacctc ttgtattcga
    28201 ttggttctaa tgttatcaaa aattttatca aaaaggtagt ctttatgaaa aaagaaaaca
    28261 attattttcc taattttata aagaaaaaga gaataagctg caagcctttc aggctgaggg
    28321 cttatcctct tttcgactaa tctacataat acatgattgc aaacgcgtct ttaccagtat
    28381 gcgtagcgat aaccggattc gtatgcagta cagggatatg catgtccggg aataattctt
    28441 gcaaaccctc tttgaattct tgcgccaatt cttttgcatc cgcatgtgaa ataccgattt
    28501 gtcgcacatt tggcaattct ttcagttcat ttttcaaatt attaaaccat ttatcgaacg
    28561 ttttctttcc tcgcccctta gttacaggga ttaattcaga atgggcgaaa ttcatcacca
    28621 cgcgtatgtt caaaacacta gacagcaaac cagttgttcg gctgattctt ccacctttta
    28681 ccaagttatc tagtgtggat attccgatgt ataattttgt attgtcttgt acttttttga
    28741 cttcttcaag gattttctct actgttttac cttcttttgc taattcagct gctcgaatta
    28801 cctgaaaaga taatccttgg tcagtggtat cactgtcgat aaccgttact ttcgtttttg
    28861 ttagattact ggcttgtctt gctgcttcta ctgttccact caagcctttt gtcatatgga
    28921 tcgaaatcac ttcactgccg tcttctccta gctcatcata catcgagatg aattctccaa
    28981 ttggtggttg gcttgttttg ggcagatttt ttgctttcgc catcatttcc ataaatcttt
    29041 cgccgtctag ttggtcatca tcgggatata ctgttccgtc gatcatgatg gatagcggca
    29101 tgacacgaat gcctaaagca tcgcgtacat ttttttccat cgtacatgaa gaatctgtta
    29161 cgatttttac atttgtcatt attttctctc tctctttctt taacaagatg ccttattcat
    29221 gttaaactac atgtaagaca atttctattt ttagtataac agacaaataa tgatttttca
    29281 ttaattacac ctagtaaagg agccgttttc atggaaaaaa cgaaatttaa tcgaacgtat
    29341 gaaatattaa atgaagtgtt taatgcagtc acccatggaa ttgggactgg attgagtatc
    29401 gcgggactag tggttctttt agtaaaaggt gcccacttgc attcctccct ccatattgtc
    29461 tcttatgcta tctatggatc gatgatgatt cttttatttt taacgtctac tttgtttcat
    29521 tcattgattt ttacaaaagc aaaaaaggtg ttccaagtat tcgatcatag ttcgattttt
    29581 cttttgattg caggaagtta tactcctttt tgtttgctga gtatccgagg atggctaggt
    29641 tggactttat ttgtattaat ctggttgttt gcgattcttg gcattatata taaagcgttg
    29701 acgttgcata aacgggagag agtatcaaaa gtatctacga tcatctatat ttttatgggg
    29761 tggctctgtg tcgtggctgc tgttcctctt tatcactctc ttggaatgac tggtgttatt
    29821 ttgatggtag caggcgggct ttcttacacg ataggcgcat tcttttatag cttgaattct
    29881 atccgctata tgcatgttgt ttggcatttg tttgttatgt taggtgcagg ttttatgtac
    29941 ttctctgttt tattctttac ttaataaaaa aaataaagct atggatggga cagctctaaa
    30001 taacagctag tctatccata gcttttttat atcgtcaatt cgcctgtccc gctttttaca
    30061 ggattctcat tacgctgata cgtttcaaat tgatgcggat aacgattttt ttcatccatt
    30121 tctccttgac tagtattgat cagtgaccaa tcagaccagt caacaggtgg aaaataagca
    30181 tctccatcga atacatgatg gatgactgta cggtataata tcgtacaaaa tggcagaaat
    30241 tcttgataaa cagctgaccc tccagcgatg aaaaagatac cgtctgtttc tttttccaga
    30301 gcaagcacgt cttccacact atgcatgaca tgcacgcctt ctgctttata ggaagaatct
    30361 ctcgtcaaaa caatcgtctg acgattcggc aacggacggc tacccatccc ttcgaatgtt
    30421 tttcgtccca tcactagtgt atttgcttct gtcatttgtt tgaagaattt cagatcattt
    30481 ggcaaacgcc aaggaagacg gtcttctttt ccaatcaatc cgttttcatc ctgtgcccaa
    30541 attgcagcta acattttctc atcctttctg attctaaaca gcgataggag ctttgatcgc
    30601 cggatgtggg tcatatcctt ctaattggat atcttccatc tcaaaatcaa atactgactg
    30661 cttttcctga ttcaaaacta aagtcggaaa tgcgcgtatt tctcggctca attgttcttt
    30721 catttgttcg atatgattga tataaagatg agcatctcct aatgtgtgaa caaattcgcc
    30781 aaccgctaaa cctgtttcat gtgcaattag gtgagtcagc aacgcataac ttgcaatgtt
    30841 gaacggaacg cctagaaaca catccccact gcgttgatac aattggcagc ttagccgtcc
    30901 ctcttgaaca taaaattgaa acatcgtatg acaaggaggc aaagccatgc taggaacatc
    30961 ttccggattc catgcagaaa cgatcaatct tctagaatca ggagtctttt tgattgcttc
    31021 gatcacttgt ttgatttgat cgataaagcc accgtctttt gtttcccagt gacgccattg
    31081 atagccgtag atgtgtccaa gatcgccgta tgtttcagca aaggaatcat cggttaggat
    31141 cttctcgcaa aaaagcttgc tctgcttttt atattcttca ttgaattcag gatctgtcaa
    31201 acatctatgg ccaaaatcag tcatatctgg tccattatag tctggacttt tgatgtagcg
    31261 ttcaaatgcc cattcatccc aaatatggtt tttattttgt aatagatagc ggatattcgt
    31321 atctcctttt aaaaaccaaa gcaattcgct tttgatcaat ccaaaaggta ctcgtttcgt
    31381 tgttaacaaa ggaaaccctt tttgcagatc aaaccgcatt tggtatccga ataagcttaa
    31441 tgtgcctgtg cctgttctgt cttctttacg atgcccttct tccaacaatt ttcttcctaa
    31501 gtcaagatac gcttgttcca tcctttttcc tcctaatctt ctacccattc actcaagtat
    31561 tcccaccgtg ccattttttc ttcaagttgt gcttctgttt cagatacgtc gttttgcaat
    31621 tcttgtaatc gagtgaaatt atctccttga tgattcatct cttcttggag caatgagatt
    31681 ttttcttcaa gttctgcaat ctcatcttca atcgtttccc attctttttg ttccatgtaa
    31741 gataatttct tcttttcagc aggttccttg ctctgtattt ttggtttcgc tttttcagca
    31801 ggctgctggg tctctttttg cttcagtaaa taactggaca tgtttccgta ataaagttct
    31861 tgttttccgt ttccttggaa tactaataac ttatctgcta ccttgtccaa gaaataacgg
    31921 tcatgggaaa cagtgatcac agcacctgga aaacttctaa aataatcttc caaaatcgtc
    31981 aatgttgcta tgtccaaatc attggtcggt tcatccaata ataaaacatt aggttgctga
    32041 atcagcagtt tcaacaaaaa taaccggcgt ttttctccgc ctgaaagttt gcctatcagt
    32101 gtcccatgca taaatcttgg aaataaaaat cgttcaagta attctgctac tccgatttga
    32161 ctgccatctg ctgtttttgc ttcttcagca gcttcttgta agtaagcaat catccgttta
    32221 tctggtgcca tttcttcatt ttcttgtgta taatacgcaa gatgaaccgt ttcaccgata
    32281 gacattgtac cgctatccag gggaattctg ccagctagaa tattaagcaa tgtcgatttt
    32341 cccgcaccat ttttaccagt aatacctagt ctttcccgag attgaatcaa taaatctaaa
    32401 tgttctagca gtgtttggtc atttatacgg taactgccat ctttgatttc cagtactttt
    32461 ttccctaaac gttgtgtcgc taggttcagc tctaaatcat cttcttggtt tacttggtac
    32521 aagttctcct ttagatcttc gaaacggttg atccgtgctt gctgcttggt gccacgtgcc
    32581 tgtacgccag ccctcatcca agctaattcc tgtttataaa gccgcttgcg cttttcttct
    32641 tgttctactt ctacacgatc acgttctgct ttttctaaga cgtaagcttc ataatttcct
    32701 ttatactcgt ataattttcc aaatgaaagt tcgaagattc ggtttgctac tctatctaga
    32761 aaataacgat cgtgggtaac catcaatagt gcgccacggt attgtttcaa atagttttcc
    32821 aaccactcga tcgcttcata atctaaatgg tttgttggtt cgtctagtaa tagtaaatcg
    32881 ggttcatcaa tcaacacttg cgccagacta actcgttttt tctgaccacc tgataaagta
    32941 ctgatttttt tatctaattc actgattcct aatttttgca aaataatctt tgcgttggta
    33001 tctgtagtcc aagcatcttc tttattcatt tgttcttctg ctttagcata acgtttttgc
    33061 acatcagggt cttctccgtt ttcccctagt tcgatcaatg cttcctcata tgctcgaaca
    33121 gtttggatca aggggctgtt tccttgaaag actgcttgga gaacagttaa ttcatcggaa
    33181 aattcagctg cttgagaaag ataaccaata cggtaatcag ttggataaaa cactgtttgc
    33241 cgatcaccgt cgctgctatc gataccggca ataatattta agagacttgt tttacccgtc
    33301 ccgttcgtcc caatcaaccc gatacggtct ttttcgtgga ccaaaaaaga aatctggtca
    33361 aacaaatctt tttcaccata agtttttttg aggtcagtta cttttaattc tttcaacatg
    33421 ttccctcctt atcttggata ttgtatcata aaaatagtga acttcaggaa aatttttttg
    33481 gtatttgttc tttttgtgtt ctcaaaaaaa gaacaggacc gattcgatcc tgttctgata
    33541 tgttttgttt tttataaaac ttgaaaattt ttaccttttt attttattgg actcgttttt
    33601 tttgactttg ctcgaaacgc aaatcggaaa gaaaagttat cagatggttt gttcatcgta
    33661 taagattcta acaaattgat attcctgcga tagctgttcg cagaaaacgt cgtgattttt
    33721 tcagcaactt cgtattcatc aatgattttt ctttcaagat aataacctct tagcattttt
    33781 ttcgtaaaca gactatcttg ctggatcatc cacgaagaaa tcaaattccc cgagttcatt
    33841 tttattcctt caagtttgcg ttgctggata aaaaattgaa ccatcgtttc atcataaata
    33901 tcagtcaagt tatctaaact ttcaataatc aactgagtat ttttttgata tgtctctctg
    33961 atttcttgga tatcttcatc actaataaat gtctgacgat cagcatatct tctttgccaa
    34021 aacattttcg gatggagaac gattcgcatt aacctacgga caacaatgaa ccaaaagccg
    34081 ataaaagaca aaatctggct tgtgatagaa tgttcgaatc gagaaagaaa acgggagtaa
    34141 aaacgataac cattagaaga aagcttgccc gaacgataac tttcatccaa tccatcccgt
    34201 tcgatcgaca aaatcagtgc ttgtatttct tgtacttctt gcttttcatc atcggttaaa
    34261 tcttccaagt acagatcacg tatccgttct tgataatttt ctatcactgc ttcagtggct
    34321 aaaaattctt ttgtattacg atcaatttcc tttatttctt ttcgcaaaac ttcaacgacc
    34381 tcttctaaaa tcatcaaagc attcaaatcc gtgcttttcg cttcctctgt ttccgtcagc
    34441 ataggcaaga caatgatccc tatgaccaaa gtcactaaga tgacacccgc cgtcagaaac
    34501 aaaagcaaag accgctggta aaacatcata ttattgattg aaaatggcaa aataaaaatc
    34561 gtagccaaac tgactgttcc ctttacaccg ccaaatgtta agatcaagat ctcgttcaac
    34621 tgttttttga actttttact gccatctttg aatacataaa aaagactgat agaaatgaat
    34681 ctgatcacaa aaagcatgac agagattaat acgataatcg ctaataaaag accgtttgga
    34741 tataaaccgt ctccccatac tggcgagaac acttgcgtca attcgattcc taaaaatata
    34801 aatactaatg cattcagtgt aaaagcaata gttgtccatg tactgtggga caagctcgac
    34861 aattctgcat caaacacaga gattttccta aaaccagaag cttggagaat acctgctgcc
    34921 actgcagcaa tgattccaga tacatcaaat gcctctgcca atacataggc tagaaaagga
    34981 agcaaaagtt cgatcagcag ataccctgtg acatcttgtg ctgatgcttt ttcgatcaaa
    35041 tgaattattt tttgtttgaa ccagacaagc aaaaagccga tcaaagctcc cccaatacta
    35101 gaaactacta gactcatccc cgcgtttact gctgaaaaag atccggtgat cagcgcacca
    35161 agagcaaact ggaaggcagt aacaccagat gcatcattca aaagaccttc tccttccaaa
    35221 atatgcatcg cctttttagg gatattcact cgtccagaaa gagaactgac tgctaccgca
    35281 tctgtcggac ctaacgctgc tccaaaagca aagcaggcag caagtgggac acttggcaac
    35341 aggaatgata acgtcgcacc taccccgaca agggtcaaaa tgactcctcc aaatgccaag
    35401 aacaaaattg tcccgaaatt tttgagaatc gaagaaatat ctgctttttc tccttctcta
    35461 aataacaatg gtgcaataat cataactaag aacaattcag gttcaaaatc gattgattgt
    35521 ccccactctg tcagacctaa taccactcca aggaaaattt ggatcagtgg agctggaatc
    35581 attggcaaaa tgcggctagc tatgttcgat aaggtgatcg ttactgcaaa tacaataact
    35641 aactcagcaa attccatcgt ccatcccctt tattttttat tttgtgtaag catttttaaa
    35701 aattgttctt ttttctttaa aattttggtt tcgactactt caacctgtgt ttggttcccc
    35761 tctaattcac actgtacacg ttttgactcc aaacgaagca gatcatgttt cagacgttcc
    35821 aactgacgat acatcaatat atttctttta cgcaacttac aaagtatttg acggcggtca
    35881 tccatcgaaa gggcgccata gcgatcatgc aacagttttt tttgttgttc aaaactctct
    35941 ctcattttcc agatctccta tacacaaact tccatcatta tagcaaagtt ctttttggat
    36001 gaaaaatatt tcattgtttc atcgtttatt gctagttaga aatttccata aatttttcaa
    36061 cgcctcattc tattccaaat agtatcagat atcaagtaaa acttaagaaa gataaaagtt
    36121 tctgacaaaa ggatgtttac tttcccattc ctgcctttct tgttctttta tcacaacaaa
    36181 aaaatggggc tgcgacaaaa atcttgtcac agtcccttat tctgaataaa cggtgtggaa
    36241 gagacagcct atcagtagta ataagacaca tctctttcac agcctcattt ttgcgtaaaa
    36301 atcgatttat tcgaaaaatt ccccgtatac atcttctaca cgttgatctg gattgatcac
    36361 gatatacaag ttacctgttt tttcgctgat ttttgttgat tgatattgat tgtctaatcc
    36421 ttctgttcct ttatctagat atgggaagta cacaagatca ggtgtgccat ttcggtaaag
    36481 gatttccatt cgctcgatat cttcgtattt caatgcgcga ttaaacatgc ccatttccag
    36541 tccgcctagg ttgatatcat gtgtcgcaac tgcgtcccct tcatggaaga tttcgatttt
    36601 aaatccagca cacggatgga tttcaacaaa ttcactgcca ttgattcgtc caaaacttgt
    36661 tgtgatttgt ttgatccaaa gatcgccgat atgacggcgg ttgatcgtcc aggtttctcc
    36721 atttctaaaa taaaatttta gcgctgtcat ttctttactc attaaaaaga ctcctttatg
    36781 atgtaattta ttcttgtact acctcagttt agcacaaatt tatgtaagtg gtcacatctt
    36841 atgttttttc ttctaatgac gtatctgccc actttaagta gccaacaaag ctgagcagat
    36901 acagtctagt gttttttaaa tcaatttttc tttcgataaa aaatccaaaa cctgtttttt
    36961 atcatttttt attctttgtt ctacgacggc tttttcagct aattgcaaag cttcactaac
    37021 ccacttacca ggtttttttc cagtttcttc tagcaagatt ttaccatcta ctgctaattc
    37081 gcttaatgac ttgataggta aacgatcata ggattctcct acggcatcca tctgaggtgt
    37141 ttcgtcaaaa tagatcatca attcttctac ttgcagtgca tgttttttgc ctaagaagta
    37201 caattcgaat ggttccaaag ctccagtttc tcgttgtcgt agtccttgga caagtgcttg
    37261 aacgtcttta atcatttggt tagaacactt ccacgatttc aaaaaggaac gaatctcatt
    37321 ttcttttaga tccagttggc tgatcaataa tgcccatgct tggctctctt ctttcaatgg
    37381 gacggatggt aattcagcaa aacgtaaaag tgcttcgcct tcttctttca aaccgggaca
    37441 gcaaatgtag cactctgttt caataaatgc atggattccc gcggcccgtt catttcccaa
    37501 gagcatcttg atgaattcca catttatacg ttctacagat attttaccta atagctcgtg
    37561 gttttctttg atggcgtaga aggtttcttc ctctaatttg aaccctagtt gactgacaaa
    37621 acgcaacccg cgcatcattc gtaaggcatc ttcatggaac cgctcatgag gattgcctac
    37681 agctcgcaag atctgttctt ctagatcttg cagaccatcg aacaaatcga tgatttctcc
    37741 atcttctttc aaagcaaacg cattgatcgt aaaatctctt cttttcaaat cttctgccaa
    37801 cgaacgaacg aattcgacat gatctggtct acggtagtcc tgataagttg attccgtccg
    37861 aaatgtggtg atctcatatt gttcatcatt ttctaatacc aacacagttc catgttcgat
    37921 cccaatatct atcgtttttg gaaaaagctg tttgatttct tctggaaatg cgcttgttgc
    37981 gatatccaca tcatggattg gctggttcag caagatatca cgaacacttc cacctacaaa
    38041 ataagcttca tatcctgcat tctctaattt tttcagaact ggaattgcct tttggtattc
    38101 cagaggtaat tgttttaatt tcatttttcc aacctttcct gcgtgtttct tgtcctgaga
    38161 taaagactca gttgcatggt gactgtttga caagtccgtt tcagagtctt caaggccagg
    38221 accacttcat cttgtttact cgtccttacg ctcaaagcga ttatggtctc tttgattgaa
    38281 tttttccatg tttttttcaa aaacttcagt taagtcgata ttcaatgaat tagccatgat
    38341 catcgtaacg aataaaacat caccaagttc ttctgctacc gagttaactg gttcagaagc
    38401 ctttttgctt ttttctccat aagtgtggtt gacttctctt gccaattcac ctacttcttc
    38461 agttaatcga gccatctgag ctaatggaga gaaatacccc accttgaatt gctggatata
    38521 ttcatccact tcctgctgca tactgtataa agaacgcttt ttatccatct ttttccctcc
    38581 aaaactatct taccaaaact ttaacgcaaa tcctagataa gagcaattga gaaaatcgaa
    38641 tttccatgct acatttagga aggaatttct aaatggaaat tctgtgaaaa tacataattg
    38701 aaagctggaa ttcatatggt caaacgaaaa acagtaaaag aagttctttt tatcattata
    38761 ggaacaagta tttatgcatt tggtcttgtt tacttgaaca tcgctaatca tttagcagaa
    38821 gggggagtct cagggatcac cttgatctta agagctttat ttggtattga tccagcttat
    38881 acgactttat taatcaacat cccattgatt ttactaggag gaaagatcct cggtaaacgt
    38941 tccttggcct atactgttct aggtacactt tctttgtcat tctttttatg gatctggcaa
    39001 agggttccac tagaaatcaa tttacagcat gatctactga tcgtttctct acttgcgggt
    39061 ttagttgcag gtgtaggaag cgggatcgtc taccgcatgg gtggaacaac aggcggcagt
    39121 gatattatcg ctcggatttt agaacaaaat tacggcatca ctatggggcg ttccctattg
    39181 gcatttgata tcatcgtctt acttgcttca ttaacctata tcgacttgaa acgtatgatg
    39241 tatacgttga ttgtttcgta tgttttcagt cgtgtgattg attcgatctt agatggcgga
    39301 tattctgcaa aaggtctact tgtcgtctcc aacaaaagcg aagagattgc accactactg
    39361 atgaccggtc tgcaaagagg tgtgactttc ctttctggag aaggcgcatt ctctggtaat
    39421 tcaaaaaaaa tcatctatat ggtcgttagc tctagtgaat taactgaagc taagaggatc
    39481 gtccacgaga ttgacgaaaa agctttcctt tcaatcatca atgtgcatga agtggaaggg
    39541 caaggcttta cttatttgaa gccacagaca agattactga aaaaactata agaaaaaaga
    39601 caaagatagg ctatgaggaa agattccaca tccagctgac ctttgtcttt tttagtacta
    39661 tactattttt aactaattgt tatgttcact tacccggtta cttttctttt gtgtctgcaa
    39721 aaggatcttt cggttaactt catcagataa tttcaaaaaa gcatccctat ctccatcttc
    39781 tagtgcttga tcgatttgag cataaagcat ttttagtttt gcctcttctt ctttttcttg
    39841 aaaatatcgt tcaattaatt cagtatcttc ttcactgact gaagaatccc aagaagaaaa
    39901 tggattgtct tctaagatag atagatattc tcttgtctgc caagcatttt cgaatataca
    39961 ttccacatat aaaggctttt tccaattcaa acggatttca tgaaaaatct ggtctgtgtc
    40021 cgtaaattct tttccctgca aaaacaattt catgggttcc ccttcaacag atagatcact
    40081 gatctgcagt cctcgatccg caaaattcgc cccttcaaca aagtggacat tgcttaaaat
    40141 cgcttcatga ttggcaagat aattcaagat ccaaaaaact tctcttcggc taaaagatac
    40201 atgattgacc atccacgtta aaaaattctt cttttcccgt acatcaatta gcatttttct
    40261 cacctctctg ttaggtcatc taataatgac agtgcctcca tatctcctgg ttcaagtgtt
    40321 aaataataag tcaataattc ttgcgctctt ttcagctgcc cttcttctct taagaaaaag
    40381 gcatactctt tcaagaaatc tggttcatgt gatagttcat gataagcctg ttcatagtgt
    40441 acagctgcaa cggtaaagtc ttctaattca ttataagcat gggctaggtt ccattctgca
    40501 taaggattag cagtttcttc catctgattg atcacttgta tcacatcttc atatctttca
    40561 tcatccaagt aaagattact taaagtaagt aatgtttcat cttgtttgtc tcctacttct
    40621 aaagctttca gtaaaagttc ttctgctcgc tgtctatcat gcagacggaa agcattttcc
    40681 gaggccaggt gataaagttc gacttggtaa ggattttctt tgattccttc ttctaacact
    40741 gtttgtgctt cttcaatcat ttcttcttct tgaagagctt gtcctagata tagatataac
    40801 gattgataat gcggattaac ttctcgaagt tcttccagat agttgattgc ctgctgattt
    40861 tctttcaatt gaagattcgt aaaagctagc tggaacagtc gatcatctgt cctttcttct
    40921 ttcagtgctt cttctaaagg tacgatagct gcttcgaatt ctccttgcat acttaaggat
    40981 tgtcctaaac gttcctgcat cgagattcct gaaatttcat ttatcccgct tgccaacaat
    41041 gtttcataaa ccactgctgc ctctttgaaa cgatcaactg aaaaatacaa ttcagctagc
    41101 gcaaactgga tcaatggttc atcaggaagc aacccagctg cttctttcaa ttttgcttca
    41161 ctcacttcag ggattccgat aacttggtac aaatcagcta tcgccaataa gctttgcgga
    41221 tagtaatcac tttgcttatc cactttttcc aggtattcaa aagctaagtc gatctcatta
    41281 tcttcgattg caatttctgc taacgggatg ttcagtccgt cattttctgg gtattggttg
    41341 atcagttgtt caaaaatctg ttttgcttcg atcaaaaagc caatagccag caattcttcg
    41401 cctagttcag ctaatatatc tgctgggtct tcttttaatg ctttttctaa aaagatttgt
    41461 gcttgtgaca agtcttcatc tgataaagct tgcaacattt tttcgctatt tgtattcatt
    41521 tcaattccct cttatctcac tgacgatttg ttgaaatacc gtcattgttc tcaataattc
    41581 tttttcgttt ggatgttggt atccgtctat tatacctatt ttttctaaaa caagtatttt
    41641 tttgcttttt tctgccaaaa aaagaacttt ttccaaatac tccatctttg aaatctgttc
    41701 cagccagtgg attggatagc caagcaagtc cagccacaca aaaaagtttt ttagttggaa
    41761 atcaaaagga tatgcttgga gattccacac gaaatgaaac atcattccta aaaatttttt
    41821 catactagca gaaagtagat ggccattttc ggtcagataa aaagcttgtt caaacagttt
    41881 accataattt gacaggtttt ctgcctctaa ttgataaaaa tagatcattt cttcgatcat
    41941 cccggcaaac ggccgagtcg ttaattgctt tttatttgga tagtttttat acagattttg
    42001 caaaaaacga tgatcacaaa tcattccgca acagataaaa gtcaaaaagt caatctgctt
    42061 tccgtccacc tgccgctcgc tgattgtttg atcataaacg atgcgttctg gcagattgat
    42121 ggtttgcagc actacacgat ttggtagctg caaaatcgtc cgctgcggtg ttaatgctcg
    42181 gcttagagaa cggatcgata cagggatcat ccatagtgat gaatcaaggg ttgtatgttt
    42241 ttgaaaaaaa cctgccagat ccatgatccc ttcatttcca aatccgatga taaacatgga
    42301 ttgattttcg ggatagcgtt tgacgaaatc aagcaggttc tttaattctg ttaaatgatt
    42361 gcattgagtg ttggcacaaa tataccagtc attgtttgct tgatttgcaa ataacgggtt
    42421 gatcttatct gcaaacaaat cataatagcg ctgattcgtt aaaaataaga ttggctgatc
    42481 aatggaaagt tctcttagct gactgactag cgtttctccg taaaacactt tcgtcaacgc
    42541 atcttctact tgataatcaa gttccatacg catccctcct cttcttattt ttattttacc
    42601 attagtaagc aaattctaga aaagataaga gcaaagctca cctcataact tgcaaataaa
    42661 taaaaattaa ataaaataca tgtgttttct atgtatgaca tacggattcg gaatctctgt
    42721 ctcttattta ttccttttct gctaggaaat aaaaagaaaa gcacttgtag ccctagagcc
    42781 acaagcgctt tttcaactgt cttatttaac agcgtctttt aatgctttac ctggtttgaa
    42841 tgcaggtact ttgctagctg gaatttcgat ttcttcacca gtttgtgggt tacgaccttt
    42901 gcgagctgcg cgttcgcgaa cttcaaagtt accaaaaccg attaattgaa ctttttcgcc
    42961 gttagctaaa gcatcttgaa tagttgaaaa tacagcatct actgctgcag ttgcatcttt
    43021 tttagttaaa tcagtagctg aagcaacttt ttcgattaat tctgctttgt ttgccatgga
    43081 tagattcacc tcctccacaa gagatatgat agaaatatca tttagttaaa actttctgag
    43141 tggtccagaa gtttaaaaag aaatattgat taacttcaat attctgttat cacgatatca
    43201 tatgaaccgc ttaatagcaa ggtttttacc aattttcaca tgcttttttt agtcatagaa
    43261 acgtaacaaa cgaaactgtc tttttctttt gaaaaaaaaa cgtcgatatg gtaaaatgcc
    43321 tattttctcc tacgagggat aattcggatg gacgtccctt caaaagtaaa tgcttttctg
    43381 atttgatttt ctaagaaacg ttcataagaa aaatgcatca attcctcttc attgacaaaa
    43441 acgacaaatg taggtggttt gacagcgact tgtgtagcat aaaaaatctt caggcgtttt
    43501 cctttatctg ttggtgttgg attgattgct acagcatcca taatgatatc attcaacaca
    43561 gccgaagaga tacgaagatt ctggttcata cttacttgtt cgatcatttc aggcagacgt
    43621 tccaaccgtt gtttagtcac tgcagaaaca aaaacgattg gagcgtaatc aagataccgg
    43681 aattcatcac gaatctcttg ttcgaaatca cgcattgtat tggtttcttt ctttacaaga
    43741 tcccatttat tcacgacgat aataattcca cgaccagctt catgggcgta acccgctact
    43801 cgcttgtctt gttcccgaat cccttcttca gcattcagta ccatcaaaac gatatcagaa
    43861 cggtcaatgg cacgcattgc acgcatcacg ctgtattttt cagtattttc gtatactttt
    43921 ccgcgtttac gcataccagc tgtatctatc attaagaatt tctgaccact ttcagaaacg
    43981 aagtgggtgt cgattgcgtc tcgggtcgtt ccttcaatat ccgaaacaat tacacgttct
    44041 tctcctaaaa tcgcattgat caaagaggat ttaccaacat ttgggcgacc aatcaaacta
    44101 aacttaatcg tgtcgtcgtc ctcttcttca gtctcttcag agaaatactt cactgcttca
    44161 tctaaaatat caccaatccc tagtccatgg cttcctgaaa caggataagg atcgcctagc
    44221 cctaaggaat aaaattcata gatatcgttt ctcatttctg gattatctac tttattgact
    44281 gctaaaatca ctggtttatt acttctgtat aaaattttcg caaccatctc atctgcgtct
    44341 gtcacgcctt cgcgtccgct gactacacaa atgattacat ctgcttcttc aatcgcgatt
    44401 tctgcttgat gcttgatctg atccataaaa ggttcatcgc caagatcaat tccgcctgtg
    44461 tcgatcacgc tgaattctcg acctaaccat tcaccttttg cataaatacg atcacgagtt
    44521 actccaggag tatcttcgac aatcgagata cgctcaccag cgatgcggtt aaaaatcgta
    44581 gacttaccga cgttcgggcg gccaacgatt gcaattgttg gatttgccat attatttcct
    44641 cctcacaagt ttccaatctc acttagttta acgaatgcat tgccaacttt caagcataga
    44701 ttgtcaatta aacgaagtat ttttattcct tattgaaata ctaatcgctt ttcaaaagaa
    44761 aaactgagac aaaagcagct gctttcatct cagtcacaga tacaaaatca attatttttc
    44821 agaatcatcg gttgcttttt cttctacttc ttctttcaac gcatcaccta aaatgtctcc
    44881 catagtaaat ccagtatttt cttctggtaa ttcataagac tcaacatttt ttggttcttc
    44941 ttctgaagct ggtttttctt ctaaagcttt gatactcaat gcaatacgat gttcttctgg
    45001 atggatctct aatactttca ctttcacttc gtcaccttca tgaagcactt catgtggtgt
    45061 cgcaatatgt ttatgtgaaa tttgagagat atggactagc ccttctactc cagggaacac
    45121 ttcaacaaag gcaccgaagc ttgtcaaacg tttaactgtt ccgtctaata ctgtgccaac
    45181 tggagctttt gtatcgattt ctgaccaagg tccaggctgt gtgtctttga ttgacaagga
    45241 aacacgttct tgttcaggat tgatagacaa cactttgaca tttacatcat cattgacagc
    45301 caatacatca cttggttttg ctacatgact atgtgaaatc tctgagacat ggactagacc
    45361 gtcaattccg cctaggtcga caaatgcgcc aaaatcagta agacgtgcaa cacgtccact
    45421 gagaacatct ccctcatgga tagttgaaag aatttctttt ttcttttctt ctctttcgtt
    45481 ttccactacc gctttatgcg ataagatcaa acgattttct gatggttcga tttcgatgat
    45541 tttaaagctc aatgttttgc ctttatagtc tgaaaagtct gcaacaaaat gatcttccac
    45601 cattgatgca gggacaaaac cacgtacacc gacgtcaacg actaaaccgc ctttgacaac
    45661 atttgtaaca ggtgcttcga tgaccttgcc ctcttggaaa tctctttcga tatcttccca
    45721 aactttttta gcatctaaac ggcgttttga aagtagatag ctgccgtttt ctttatcttt
    45781 gccgatcgta ctgataacga ctaaatctaa tacatcaccg acttttacta cttcgctgat
    45841 atcttctacc ggcaaagttg ataattcttt tgccggaacg actccttcaa ctccagcccc
    45901 ttcgattccg acaatcactt gtttgtcttc aatgactaaa acttcgccct taacaacatc
    45961 gccaactttt acttcttgta cgcttttcat tgcgtcttcc attgactggt tgttctcttg
    46021 attttgatca aattctgtca taacacttgt cctcctaacc aacattctgc cgtaagtacg
    46081 gtactgtttt tagtttaatt gattattcaa aaaaaataaa gcgatttcgt tcgttttcct
    46141 tgaaaaaaca attgtttttc attttttttc ttaatttaaa aaagaagata accttttttc
    46201 aaaacaacag cttttattgc tgcaacgact tctggaatcg atttgccagt cgtatcgata
    46261 cgaacagcat cctctgcttg cttcagcgga gagacgtccc ttgttgaatc ataatggtct
    46321 ctttcctgta tctctttcgt cagtgtttca agatcagtcg gaattccttt ttcttggttc
    46381 tctttgaaac gtctttctgc acgctcactt acgcttgcta ctaaaaagat tttcacttct
    46441 gcattcggta atacagctgt cccgatgtct cttccgtcca tgacaacgcc accgcgttcc
    46501 cctatttttc gttggacagc aactaattct tctctgactt ttccatgtgc agagacttca
    46561 gaaacagctt ttgtgacatc tggttgacgg atttctaaag tcacatcttt tgatgctatg
    46621 aatacatgct gtccatcttc ttgttgcgaa aaagagatag gatacttttt gatcagcgaa
    46681 actagccctt cttcatctga aaaagataca ttgttcgtaa tagctaaata agttactgcg
    46741 cgatacatgg caccggtatc tgtataaata taattcaatt cttttgctaa tatcttggca
    46801 acggtacttt tcccagatga agcaggcccg tcgattgcaa tactgatttg tgtcatgata
    46861 taactccttt ttctcagaaa aaaagccgca aagcgcggct attattattt aattcttaat
    46921 tcttgaccag ggtaaagcat aaagttgttt ggatctaagc cattcaattc aaacaattga
    46981 tcagtggtga tccctgcacg ctcagccact tgttttggac cttcgcctgc ttgaacagtc
    47041 gttgttgaac cggctgcagc tgatgaagaa ggtgttgttt ctgctgcatt gctgcttgaa
    47101 tcccctgctt gataagttgc ctcacttgag gaagtcggtg ttgtctctgc tgcaatactg
    47161 ctttctgacg ttacacctgt atcttgagac acagtagatt cttccgcgat tgtactagat
    47221 tctactgttg aagtctcagt tgactcctct tttgttgtac ttgtagaact ttctactact
    47281 gatgtcgaag tttcagaaga agttgctgct gttgcattgt tgcttgatcc atttctgatc
    47341 cagaaataag cacctgctgg aatagcgata cataagacca gtaaaatcaa aaatagcgaa
    47401 agaaataatg tatttccttt cttttgttgt ctctgagaac ttcttgatga aacttcatca
    47461 tctgtatcgt agattggttg ttcccatggt tcttgtgttt cgttattttc tgtagattga
    47521 tgtctatctt ttctgctcac tgttttacct cctaaactct atcgtgtgta ttataccata
    47581 ggaaaaagtg tcttgtccta aaaaatcaat gttccatgtt ttttttaaat aaatttagta
    47641 aaatcgttcc ccaatgaagt tgttcagtct tagaaaaaag cttcctcttt ggcagaagtt
    47701 ctgcttttgc tccatcaata tcacaacaat tctgcggctt ttcggagagt ttttcgccaa
    47761 aataagctaa gatgaatttt ctgcggcagt tttcttcatt aatatagcga agcatctgct
    47821 gcaggcggaa ttctttttct ttttcctgac gtttgagccg ttccacccaa ttttctggtt
    47881 tttcagactg ctggatcagc tccatccatt ttttttgcag ctcatcaaag ggagcttgct
    47941 ctgtggcata ttccaaataa agctcaaaac tttgtcgctg ttctctagaa agttgattaa
    48001 agaaataatg gatacgttca tccccacttt gataaaaaag aattgctgca ctttcttcct
    48061 gatctctgcc tgctcgaccg atttcttgta catagttttc tagactgtct ggcaaatcat
    48121 aatggaccac ataacggata tcagatttat cgatccccat accaaatgca ttcgtagcaa
    48181 tgagaaactg cagctgattt tttacaaact gctgttgaag ttgtcttctt tgagctgcat
    48241 caagaccacc gtgatagtat ccaactgtaa aacgttccct gaataaatga tacaatcgtt
    48301 cgacttcttt ttttgttgca caataaatga ttgccgctcc ttgtgctctt tccatgaagt
    48361 gttcaagttc ttgttctttt tgctgcgttt tccgaacaaa aagcgagata ttttgccgat
    48421 tgactgattg tctgatctct tttggtggtc gatcaaatag tacatgacgt atatctcttg
    48481 ctactaaatc tgttgctgtc gccgttagtg ccagtgtgac cgggtttcct aaaagctttc
    48541 ggatttttcc taactgttga tattctggac ggaaatcaac tccccattga gacacgcaat
    48601 gagcctcatc tactacatat aacgcaatat tttgtttttt cagatgctct aaaagagaag
    48661 gattagtcaa catttcggga ctcaaaaaca aaaatttata ttgcgataga tgacggagga
    48721 cgtatcttct ttcagattgc gaaagtaaac tattgaaagc agctactcgt ttctcccctc
    48781 gtttttgtaa ttgcgtcact tgatcttcca ttagagaaag cagcggtgac acgatgatga
    48841 ccagaccttc cattaaatac cccgtcaatt gatagcaaag gctttttccc gttcctgtag
    48901 gcaaaatagc gagagtatct tctccatcaa gcaacgcctg aataatttct tcttggccgg
    48961 gacgaaatga atcaaatcca aaatattttt ttaattcatt tattaacatt ctgtatcgct
    49021 tcctttctca atagatagat ttgatacaaa cgaaattctc cataatctaa ttgtccatct
    49081 acattccatt cgctaaagcg ccactctcgc acggaatcct tatttggttc caaacgttcg
    49141 attgtttctg cagagagaat ccactcgtat ggaaaatcat caaaaaacaa ggcccactca
    49201 ataagatgat ctgttactgt tcctcttttt aaatgacgga ttgccatgat ctggtcaatt
    49261 gtctgaccat tcataaacat ctgcttggtg atcatcatgc tttgattgaa attttgctgt
    49321 aataatgaat cgatcaaagc gtgccaaagc gaatctggcc gtttttcgat ttgtgctaac
    49381 aaaaggtgga tacatctgct ttgttgcaga taaaccgctg actcatcatt gttttttgcc
    49441 agctgataag gaagcagccc tgttcgctca tttccagata attggttagc taaaaaatct
    49501 gctgcttctt ctggtatctc cgaaaacagc tgcaccaaac tctcatacgc agtatcaatc
    49561 aaaatttcac gtggcaattg gctttcacta agccattttt ttagttggaa agtataaaaa
    49621 ggacttgtct ctgctggaag atagtcttga atacccgttg ccagattaga aattacttga
    49681 acagcaaatt taatgagccg ccaactagtt tcccctgttc tgccatagcg gtcaaaacgc
    49741 aaaccagtat gttctatttg atgttcggac aacatatcag cccctgcagg cgttagcttt
    49801 gcttcatttt catttatttc gatccaacct tgctgcgcaa ttttttgcaa aatttgataa
    49861 aacttatcct gcttcaattc tggaaaactg ttatggataa acaaaagttc gtgggtaaat
    49921 ccataaataa gtactgaagt cgttcgtttt cccacaagga gttggtaaag agaactaatc
    49981 cgcagcttgt gtcctgatga aaatagcgat aaaataaaaa caatcatatt attctcctta
    50041 agttaggatg gttagaaatg tcactactat gtaaacttgt acctgaacgc tgtattgcat
    50101 gcggtctttg tcaaatcgaa gcgccagata ttttcgatta tgatgaagaa ggaatcgttt
    50161 tatttgccca agaaccagag gctcatcaac agttcgtgat gccggaagaa gaaacatatg
    50221 taaaaaaagc gtatcaaaaa tgtccagttc gagcgatttt attagaaaat aaaatataaa
    50281 tataaacgaa actttaaaaa cgtacactaa gttctctaaa cttgaaaata agccgggatc
    50341 tgtttctctt gttccgtgaa atcccgactt attttgaaag attcatttgc tatctatagt
    50401 taattgacta gttttttcac ggaccctata ggacccattt atattatttc aactttttca
    50461 gccagttttc caatgtattg acgatcacag tttgctggtc tgcgttagaa atttctgcct
    50521 ctccatctcc tttttgctca ccatagctgc caaaacctcc atgatttccg ccattgattg
    50581 atacatactc tgttctttcc ggtaaatact gcttagcttc ttgataagct tcctgattca
    50641 atactttatc ttttgtcgcc gtgatcgata aaacaggaac agctgattct gtcaatgttc
    50701 cttttttgtc gggataactt gccatgaaga ataccccttt taaatgtttg tctgaatgat
    50761 tcttattgac ataacgactt gccattacgc cacctaatga atggccaccg atcacataat
    50821 cggaatttgg aaaatcttct ttgaccttat ccgctttgtt tccgcccatc actgctagat
    50881 caagtggcat tttgacaata gcgactgaaa agccgttttt tgctaaatct tgcgcccaaa
    50941 tactataact ttctggctct acgagagcac caggataaaa aataagtaat ggagactttc
    51001 catgattctt tttctctcct tcaaaaaata agtaatcttc tttgtttttt ccttctttta
    51061 ccaacacttg cgcttctgac gatggttcgt acgtattttg ctgtatatag taataaccgg
    51121 ctccaccgag taatcctaaa atgatgacta agccaattag tattcgtcta aatattttca
    51181 ctttctccca ccttttctat ctgagtgacc cctttttctt aatcaagtat gattatacct
    51241 taaaaaaata agagagaaat gcaaactttc cagcatcaaa taaaaaaaga cggaatatcc
    51301 atttgaatat ccgccctttt tgtatgttta tttttattta gcacataaac gatacacagc
    51361 ttctgcataa atttccattg ctttatacat actacttaat tcccatcgtt cattcgcctg
    51421 gtgcataaag tcaggagtat cagggaacat cgcaccgaat gccacacact ggttcatcgt
    51481 acgagcaaaa gtagcgccgc ctgatacaaa cggttcagtc atgtctccag taatatcgcg
    51541 atatgtcccc aatagatttt tcactaactc actgtctagt ggcacgtata atgaatcaag
    51601 gaagtcaaat tcttcataag tcaacccata tttttctgct gttttagtta atttagctac
    51661 taaatcatct ttcttgaatg taacagggat tctcatatct acaccgattt ttgtttgttc
    51721 tggtgtgatt tccaaacttg caaagttcat cgttagctcg ccggattgtt catcttctgt
    51781 tttgcccacg acagcttcac cagttgcatt ttcttgaact aattttccta agaaattgat
    51841 tgggccaaaa tcaaatactt ctgaaagagc aattgccaga cgagaaatag cattcactcc
    51901 ttgtgctgca tctttcgcgt ggatactttt accaagaacg acgatgcctt caccttgttc
    51961 ttcgaaatcg aattcgtgtt ttttcaatgc ttcttttact tcagaaagct tttctccaga
    52021 gtaaggagct gcatcaggaa caacattcaa cgctcctcca gcttttacag aaaactcgtt
    52081 cgttcctggt cctgtcaagt aagcttgcaa taagcctttt tctgcataaa ttaaaggaaa
    52141 ttcagcatct ggcgcaaatc cttgcgtaat tccttcttct ttttcgttat atttttctaa
    52201 acaacgccat aaattttctt catctgtacc aaagataaaa cgaatacgtg tcttgaattc
    52261 cacgccagca tcaatcaaag ctttgacggc atacattgcc gcaatagaag gacctttgtc
    52321 atcttgggat ccgcgaccaa ctaaccagcc gtcttttata gttggatcga atggttttgt
    52381 ttcccaatta ttttcgtccc ctgctggaac aacgtccata tgacacaaga taccgaataa
    52441 ttcatctcca gagccaatct ctgaataacc gtaatagcct tctggatctt taaatgttct
    52501 aaatcctagc ttttcactga tttccaatac tttatccaaa gcttcaatca cttttttacc
    52561 gaagggatgt ccttgtcctg aatctgcttc atctagtacg gaaggaattc ggatcaattc
    52621 gctcaatgat tctaatgctt gttcatgatg ttgttctgtc acaaattttt tcatgatatt
    52681 atcctcctaa tatgttaaaa agggtcatgt caaattcctc cgacacaacc tcttcttctc
    52741 aaataatgac gttttaagcc tgctccatca gcaagcagaa tgttcttaac aaatgatgaa
    52801 agaaaaaaca ctcactgaat ggagctattg acttatccac gtgcttatcg atagccgttt
    52861 atcggtttct tcattcttat gatagacctt gtacctgtat ttgtctaggt ttagaacatt
    52921 gctgctacac ctaggatcac acagatggct acaaataata tcgcaattaa tttaccggta
    52981 aatttccacc acactgaaac atcgaaacga gcaattgcta cagcacccat tacgatagca
    53041 gatgttggtg taattaagtt tactaaacca gatgcagatt gataagcagt gattactaaa
    53101 tccttaccga cgccggcaaa ttcacccata ggtcccatga ttcccattgt tgcagcagct
    53161 aagccggaag ttgaaggaat caagaatgac atagggatat agaaaataaa tgtaataatg
    53221 atgaatacac ttgaagataa tgaacttaat ccttgttcgc cccaatgtaa gatggtgtct
    53281 gtgattaatc cattgttcat aaccacttgg ataccacgag caacagctac tacgattgct
    53341 acaccgatca aatcagaagc accagctaaa aattcagaga caaattcaga ctctttcatg
    53401 ccataagtga ttgctactac gatggacatt actaagaata acatagtaat ttctgggaag
    53461 taccagtcac ctaatggaag catgctttta cctagaaccg tacctagtac cggaaggttt
    53521 gttaaccagt ttgtcaatga ttcaaaaatc gtgaaattcg cattcaaggt tgtccaagga
    53581 atcaaactga tgatcatgat accaaaagta ataaagaaca atacattaac atgtttttgt
    53641 tttttcgtga ttacttcttg acgaccgatt gcttcaatat cgaaatgctt catatcttct
    53701 ttacgttggt tgtatactaa tgattttgtt ggatcttttt cgatctttga tgcataacga
    53761 tacacatata caatagaaat agctaacaaa ataacgaaca tcaagaatcg aagaccaata
    53821 ccttcaccca tcgaaatccc aacagcttgt gaagctacgc ctgttgcaaa aggatttacc
    53881 gttgaagcta gacagcctac ttgagaccct actaatacga ttgctacagc tactactgta
    53941 tcaaagccta cagccatcat gactgggatc agtaaagcat agaatggaat cgtttcttct
    54001 gccattccgt aagtagagcc gcctaatgca aataacagca tcaatactgg aataagcatt
    54061 ttttcttttc ctttgaattt cttcacaact gaagcaatcc cggcatctag tgcccctgtt
    54121 ttgttgataa tacctaaaaa tccaccaaca accaaaatga agaaagagat tgggattgca
    54181 gcaggtgttt ctttagttag ctcccccgct ggtacaccta gcatcccatt gattggcgcc
    54241 atgaaaatat cccacagccc ttgaggattt tgttgtactc gttcatatga tccagcgacg
    54301 atgttgcctg catcgtctac actatagtgc ccagctggta taaaccaagt aagtacagcg
    54361 attactgcaa taataataaa taagaccgta tacgctgaag gcatttgaaa ttttttcttt
    54421 tttgtttgtt ccatcttctt cttcctttct tttccgttag agacaacaat tttggctcta
    54481 atgttatttt atcaaaaaga gtatcagaac aaaaataata acacgcattt tgtaaaactt
    54541 ttgttcaaaa agttcgtttt tccctattcc ctcctctttt ttcaggtttt taaagctttc
    54601 ttctttttca ttgtagcgtt tccttttttt tataaacaaa cattttcgtc ttttaaaagg
    54661 agaagaattt cacatttgca aagaattgat tgatttttat gcataaatca aaaaaatact
    54721 caaaacaaac aaataaaacg tttacattat tgcatgtctt gtattttttt ccaaaaaaaa
    54781 agaccaagaa atttcttgat ctttttgata tttatttgac tgctgtatga cgttgttcga
    54841 actgatgttg ttttcgactt aaccatggaa gaagttgcgc atgcagcact aaaaagacag
    54901 cactcacgat gaatcctttg atcaagttga aaggaacgat cccaatcagt acatagtttg
    54961 ctaaagacat gcccagcatc tgtgttgcgt tcagccctaa aaacattaag taaagaggcg
    55021 taataacgaa ataatttgcg atactcataa aaatagttag agcgatggtt cctgtaatga
    55081 cacctaaaaa tttgtttctt cctttatgct gtttctttac actaaagaaa taataaatcg
    55141 ggaatgtaaa gatcgttgtt gataagaaac tagcagtgtc tcctaccaaa ttatccggag
    55201 aaaaacctgt agtcagcaga tgtaatactg aacgcaagaa cgctgttgca actccggccg
    55261 ctggaccgaa taagaacatg ctgatcaata ccgagatatc actaaaatcg atcttcaaaa
    55321 aactaaaagc cggcatgatc ggaaaagcaa aatactgtaa aactaatgcg atcgcagcaa
    55381 acatcgctac tgcaaccatt ttctgtacac gggtgttctt catttgaaat cctcctgtta
    55441 ggactcctct tcagcgaact ttttgacgtt tctctccaaa tgaaaaaact ctattttcca
    55501 gggaaaatag agttagagtt atttgatcaa gcgtcgtcaa ataagctcta tcttctttat
    55561 ccagactata ctgtcggtat cggaatttca ccgattcagc tatttttttg caaaataggt
    55621 cgtggactat aaccaccggt cgggaatttc accctgcccc tgaagacgaa ccttatataa
    55681 tttttgttta catattcatt atacatatct attcaaaaaa cgcaacatct aacacttata
    55741 aaaagtaagt gttcattttg agtggttcag caaactgctg acttcttttt tgttcagttc
    55801 acggtaatcc ccaggacgta ggccttgtaa agtcagatct ccgtattttt cacgttttag
    55861 tttttgcaca ggaagaccaa ctgcttgaag catatttttc acttgatgat tacgtccttc
    55921 gtggatcgtc aattccacga tactgtggtt tgtcttagga tccactgata aaatttggaa
    55981 tttagctgga gatgtttttc gtccttcgat ctttattcct tttgtcaaag gtgcaagcat
    56041 cgattttgta gcgatccctt ttacctttgc aacgtaaact ttatccactt catgttttgg
    56101 atgtgtcagg cgctgagcaa aatctccatc atttgtcagt agcaagatcc ccgaagtatc
    56161 gtaatccagt cgacctacag gatagatacg ttcttttacc atcggcaaaa gatccgtaac
    56221 aacttttctt cctttgtcat ctgcaacagc agaaataact cctttaggtt tgtacaataa
    56281 atagtaaccg tattcttctt gataaattgg gacttcatcc acttccacag tgtcatgttt
    56341 cccaactttt atccctaatt cccttacaac ttgtccgttt acttttacac gtcctgcaag
    56401 gatgaattct tctgcttttc gacgagaagt gatgccagcg tgggcaatta ctttctgcaa
    56461 tctctccatt acaattattc tcctttattc attccatcaa agaatagatc tggtgacacg
    56521 tcttcttcaa gtgaaatttc catttcttgt gtatcaggca gttcttctaa tgatttcaaa
    56581 ccaaaataat ctaagaagta gccagttgtt ccatataata tcggccgacc tggtccttct
    56641 actctacctt tttcttcaat cagtttatgg gcagctagac gctgtaccgc tcctgaaacc
    56701 tgaactcctc gaatctgctc gatttcagct cttgtgattg gctgtttata agcgatgatt
    56761 gctaaggttt cgacggcggc ttgagataat gtgtttgatg tcccttgcgc atatcgctta
    56821 agtaagggag ccagctcttt tttagtcgtt aatacataat ggctttccgt ttcaaaaata
    56881 tgcaaagctg agtgcgagtt ttgagtgtaa gattctttta attctttcac taaacttgtg
    56941 acttctgctt cgctgagatt taacagtccg cttaattctt cattactgat cccttcctcg
    57001 ccaacaataa aaagaagggc ttcaagttca cttaatttcg tcatgttcgg tatctcctac
    57061 tgctggataa agcataattg attcatagtt ttctttttgt tgcgcaatga tctgcccttt
    57121 tttcatcaat tctagcaaag ccataaaagt agtgacaact tcacttttag aaggtgactc
    57181 aaaaaaagaa tcgaaagtac agccatgcgc atttcttttt atacgctctt cgataaatac
    57241 cattcgttct tcgatcgttg tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa
    57301 tttcttacgt tctaagattt tctgcatggc acggatcaaa tcgatttttt tgacttgtcc
    57361 tcgcttcaac ggcttttcag catccgctaa cccatcgatg ttcataggtt cttttgtgta
    57421 ataaagactt cgttcctctg ctttttctgt cagtctttca gctgcatatt tatatttacg
    57481 gtattctaaa agctgagtga ccaattcttc tcgaggatct tcttcccata attcttcatc
    57541 gtctgtgacg aattcttgga caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc
    57601 agccatcact aagtattctc ctgcaacagc tagctcgagt gttttcattg tatggatata
    57661 attcatatat tgctccgtga tcgtagcgat cggtatatca tatatatcga tttccatttg
    57721 ctgaatcaga tgaagcagca gatcgagagg accctcgaat acatctaatt taatattgat
    57781 ctccgtcaac tcattcactc tttcttcttt ttctttgcta gccattttcc aatgtaaggc
    57841 tctgtgattt cagttgcacg gatggagaca tccgggtact tttcctgtaa ttcatctaac
    57901 atttgaaagc ccatattctc accgcgataa gacggattca aagaaatgtc atggatgatc
    57961 agctgatcgt tcgttgccca gtaaatacca ataatccctt gaatgttggt tgaaccttct
    58021 ggcgtaaaga aaaaaagttc ataatcgtct tcagattcgt acgtatcaat ctccttcaac
    58081 aaagaagttt tacctgtcag tttcttatgg aaactcaata gtcccatagc aattttacgg
    58141 ttttctttcc ggtaatgtgt taacatcttc tcaccttcct atgactaagc ccttggaaaa
    58201 tgctgcttat aaacatccgt cattcttttc ttcgtgatat gtgtataaat ctgagtcgta
    58261 gagatatccg cgtgacctaa caattcctgt actgtccgca aatcagctcc attttctagc
    58321 agatgtgtgg caaagctatg ccgcagcgta tgtggtgtta cttctttgta aatcccagcc
    58381 tctcgtacta actgcttcag atttttccag attccttgcc gagaaagacc tttcccatga
    58441 ttattgacaa atacatgcat ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct
    58501 aagtagcgtt ccagccattg gatcgcataa tcacctaaag gaatgatccg ctctttatct
    58561 ccttttccaa ctgtctgtac cagtccaaga gaaagatgaa gatctcccaa tttcaatcca
    58621 atcaattcac tgacgcgcat cccagtagca tacatgactt ccaagattgc acgatctctt
    58681 atccctaacg tttttgtcgt atcaggtgct tcaatcagct tttctacttc tgtcagagtc
    58741 aatgtacttg gtaatttctg tgctttcttc ggcgtatcga tatgttgcat cggatcatga
    58801 tcagtgatac gctcttgccg taaaaactga tggaatcttc tgagacttga gatcatccga
    58861 gtaacagttg ctgtcgcttt tttttcttca tgcaacttct ccagaaaacg gatgactaaa
    58921 aagcgatcga catcctgcca tgaagcaatt ttctgctcct gtagaaaatg caagtactgt
    58981 tccaaatcac gttcatagct ttgtcgtgta ttggcggaca atccccgttc aatattcaag
    59041 tagtggagat aatcgttgat ttgctctttc ataataatcc ccctcatgcc tctctatcat
    59101 atcagatacc gcttcattct gatagtcttt ttccataatc tgagcaaaga aaaagccgtc
    59161 tagacactca gacggactgg tttctttttt ctttttcata gcattcctga cagattccat
    59221 ggaacgttag ccgatgatct tttactaaaa aatgataacg ttcttctact acttgctcca
    59281 cttcaagtaa aagatcctct tctacttcct cgatcgtgcc gcagttcaag catagtaaat
    59341 gatgatggaa atgtttggcg ccttcttttc tcaaatcata acgggctaat ccatcattaa
    59401 aacttacttt atcgacaatt ttcaattctg tcaagatttc aagggttcga taaacagtag
    59461 caagtccaat ttccggactc ttttttttca ctaaaaagaa gatttcttct gcagataaat
    59521 gctctttctc attttccaaa agcacaagca gagtagcttc tctttgcggt gtcagcttaa
    59581 accccgcttc atgtagctgc tgttttgttt ttttcatcgc cgaaatagca ttcatgacca
    59641 tttactcaac cccaacaatt tataataatt acaaataaaa aaagatataa cactatgtta
    59701 attaaaatta ttataagcta gttaagaaaa acatgcaagg gattctcaat tagatttttt
    59761 gactagtttt gtcacaccgt tttcttgtgt aatcaatcct tgtttcaaaa gattacctaa
    59821 tgcgcgctta aatgctcctt tgctgatacc aaaagctttc atgatttctt ctggatccga
    59881 tttatctgta aagttgattt gctgatctgc agaacgttct aaaatggtta aaatcatttg
    59941 tgcatcatct gatatagctt catatgctct tggcttcaat gaaagattca gtacaccgtc
    60001 tggtcggaca ccaatcactc gaccttttat ctgctcgcct agacgaggtt cattatatcg
    60061 ttcagaagga tggataaacc caagatagaa atcttccgtt aaaacgtacg tacctgttaa
    60121 tttcaagcgg tatgctgttc ctatcacatc tttgtttttc atttcttctg ttccatattt
    60181 gcttaaagat ttgaatattt tttcatctgc taaactgccc caaatacggt cttttgcatc
    60241 aactctaagg gaaatcatca agcgatcccc ttttttaggc catagctctg tcattgtcgg
    60301 caattcatca agagatacga caaagtcttt atctggaaga ccgatatcga caaacgcacc
    60361 taaatctttt cgtgtagcag taacgattcc aaaagcgtaa tgaccgatac ggcttttagg
    60421 aatttgtgta gtgatccgat tttcatgttt ttgattttgg taaccgaatc cttcaactgc
    60481 ttcaccgatt ttgtgttcac cttctgattt gcttaagcca aaggtttgtc cgtttttttg
    60541 gacaaagtag tttttttcat tttcatcaat aataatacct gtaaatatag ttgctaataa
    60601 atcgttcatt tttttctccc tctatagtga aaggttttct taatacattt ctttgctatc
    60661 ataacataat gttatctact tgaatagctg agccttggtt tggaaaggtg aaaaaaggag
    60721 tatgacaaca gttgtgtcat actccccttt ttcgaataaa cggtgttaaa cggcaggctc
    60781 acagcctctt tcatttgcct aaaattaatt gctcccattt cctccgaacc atccagtttt
    60841 acagttgatg gttacgatgt aaaatggcaa agcactttct ccaatgcctt tcatcaatgc
    60901 agattttgtt gaagtggcat atagattata atagccttcc ccattttcga ttctggcttt
    60961 ttctaatctg taacctcctt caacgatata tccacgttgg atacatgtag caatcacttt
    61021 gctttggaca cctggtgccc acgtccatgc tggattagat gcatcggcaa tatcacttgc
    61081 tctggcagat ttgattggct gattcgctga gtttgaagag gaaggggtcg aggatgccgc
    61141 ttcttgctgt gctgcttgtg cgaccgcagc ttgttgagcg gcttgagctg cagctgctgc
    61201 ttgagcggct tgttttgctt gttcttcagc tgcttttttc gcttcttctg cttttttctt
    61261 ttcctcttct tcttttttct ctttatcagt gagcatctta tctacttgtt tcaattgttc
    61321 attcaactga gcagatagat ctgtattttt cactttttct actgcttctt ttgccgtctt
    61381 gtattggtcg cgtgttgctg aatccactac ttttccgtct ttaaagacta tagctgtttt
    61441 ttctttagct gtttgcaatt cagcatattg atttttagct tctgtttgtg cttgttgaat
    61501 caattttcca aaatctgtgt tatccgtttc gattgcttgg atctctttat ctgctttcaa
    61561 cttgatgtca tctgctagat gatcatcgac gatggcaggt gctatgaacc actcattcac
    61621 tttttggata tctcggatct tagattggat atcttggtaa gttgtttcta actctgaata
    61681 tcctttttca ttcttaagac tggataaatc attttttagt tttgataaat cttgatgaat
    61741 catatctgca cgaataaatt gatggtgatc atctgtataa aaggcagcaa gtttctcatg
    61801 aagttcttcc atttgttgct gtctttttgc ttctgctgct acttcggctt ctactttttg
    61861 atgatggtca taataagccc agcttcctcc accgagtaga agtactgctg ctaaaacgag
    61921 ataaggtact ttttttgatt ttttcttttg cgctttatct ggatctgttt tttctaagtt
    61981 tgattcttga tgtgtttttt cagtatctgg cacgattgtt attgatttcg cttctgcttc
    62041 aaacagctta ggctggttct cttctttttc tatttttgct tcaagatcag taccctcttt
    62101 gcttacagat tgattttcag catcggattc actatttatt tcatcgggct ctgttgactt
    62161 tttgtctgtg ttttcgagta tttctttttt ctctgcttcc ggcagtttat tcgttttttc
    62221 cttttctaat tgtttttcag taaatacttc agttttttct gtgatatccg tttttacgtc
    62281 ttttattttt actgtttctt tacctgtggc gttttctcta tcagagtctt tttcagtttc
    62341 ttgttccttt tctggctcta ctttgttttc ctgtgcaatt ttttcactga tcattttgag
    62401 cagctctttc gcgtgctctt cttttgtatc ttcacgatgt gctttgatat aagcggatag
    62461 tatcgaattt tcttcctcat tatcgacgat ttctttcagt tcagctactc ttcttttttg
    62521 ttttgattca agcgtttctt cttgattctt tcctgattct tccgaagtct catgaacagt
    62581 tgctttcttc tgttcatttt tctctatatt agttacttga tcgtgagcag gtggttcttc
    62641 gtcttctggt tctgcttttt cgaataattc cattacagat tctagaggta aatctttcaa
    62701 ttccgaccat tcgattggat cgtttaattc tgtatcagga aagactgcat cttcagttga
    62761 tttatcctgc atagctgcat ctgtatttgt ttcttcaatt gattctttta tttgctgatc
    62821 ttctgcagtt atttgatgac cgcagtctgg acagatagta ttctgctcca tttttttcga
    62881 tccgcaattt ggacattttt tcatcactta gcgatcggct cctttactag gtttacgcta
    62941 ccatttaatc tatcatattc tatacgtcac gccaatagct tatttttagg atttacttaa
    63001 aaataatgaa tgaatttcct tcctatagaa aaaaaagctt gagactgcgt agtctcaagc
    63061 tttttttctt ttaaaataaa ccaaacagtt ttactgattt ctcttctggt caatagtcca
    63121 cgcttattct aagaaatctt ttaattgttt tgaacgagaa ggatggcgca attttcttaa
    63181 tgctttagcc tcgatctgac gaatacgttc ccgagtaaca ccaaatactt tccctacttc
    63241 ttccaatgtt ctcgtccggc catcatctaa accaaaacgt aagcgaagga cattctcttc
    63301 ccgatcagtc aatgtatcta gtacatcttc caattgttct tttagtaact cataagctgc
    63361 gtgttctgct ggacttgttg cttcctggtc ttctatgaaa tcacctaagt gagagtcatc
    63421 ttcttcaccg attggcgttt caagggaaac aggttcttgc gcgattttca agatttctcg
    63481 gactttttct gttggaagat ccatttccgc accgatttct tctggcgtag gttctcttcc
    63541 aaggtcttgc agcaattgac gttggatacg tatcaattta ttaattgttt caaccatatg
    63601 aactggaata cggatcgtac gtgcttggtc agcgattgct cgagtgatgg cttgacgaat
    63661 ccaccatgta gcataggttg aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc
    63721 cttcatcagt cccatgtttc cttcttggat caagtcaagg aactgcatgc ctcgtcctac
    63781 ataacgttta gcgatactta ctactaaacg aaggtttgct tctgccagac gctgtttcgc
    63841 ttcttggtcg ccttcttcga ttttcaatgc taacgctact tcttcttccg cagttaaaag
    63901 ggagacacgg ccaatttctt tcagatacat acgaaccggg tcattgattt ttacaccggt
    63961 tggcgcagaa agatcttctg tttttgcttg ttcagctttt ttctcagcac tcttcaagct
    64021 gtgaattgat ggatcaccat tttcatccac cacactgata cctgcgtctt caatcttttg
    64081 gatcaatttg tccatttcat ctgcattcaa agtgaatggt gtagcaagct gattggataa
    64141 atcatcatat acaacttgtc gtttgggttt gttttctttg atgaaagctg ctactgctgc
    64201 ttcatacgtt tttttatctg ttccatttgc cataaaagaa ggcccccctt gagtagctat
    64261 ttggcttgtt ttaactgttt cgttaaattg atgatttcaa tcgtcaattc aagctcaagc
    64321 tgtttgtttc cagttcgtct ggcttcttgc tgcatttgtt tttttaatgt tatttcatca
    64381 gctaagccag atttgctgat cacatctagc aagtcttgga tttctcgtgg cgaactttct
    64441 tctgccaccg gtaaatattc gatttccacc accaaccgcc ttaaattttc atcttgcaaa
    64501 aagtctaaaa actctgcaag gttgaattca taatgttgtg agacatatgc atcgaataaa
    64561 aaataaactt ctgcatatgc atcatgaata aactgaaatt ctcgttcttt taaaatatta
    64621 cggacagaaa cttctttaaa tgcacgatat aatagaatct gctctgcctt ttctacttgc
    64681 gtcaaaggtc tctttttccg tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc
    64741 tgaggttctt gacgattttg ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc
    64801 gtctctctgc cgatctgaaa ctctgttgac agttgagata gatacatatc ttgttcgatt
    64861 ggtgaaacaa ctcggctaag ttcaactagt aattcttcga ggtattcgat cttgtctttt
    64921 tcattatcta aatttttccc ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg
    64981 cgcccatgag ccactaattc ttggaaagat gcttctccat acttacggag atattcatca
    65041 ggatcaagct tttctggaac gactacgaca gaaagtgcta atcgactgtt ttgccgaagc
    65101 aattcaatcc ctcgattggt tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc
    65161 aattctttcg tcagcttttc catttgttgg atctgttgag ctgttagact tgtccccata
    65221 gaagctaatc cagttttgat accagcctgc catgcagcaa tcacatccat aaacccttcg
    65281 aacaacaaaa tttctccgtt tttccggata tcgcttcttg ctttatcaag attaaataaa
    65341 acttgtcttt tattgaacag ttctgtttct ggactattca agtatttggg ctgatctttt
    65401 tcctgccctt tttcaggtgc aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa
    65461 ttacgaagtg gaaacatcac tctttgataa aaacgatcag acatacggcc atcatcatgc
    65521 gtgacaaaca atccagagcg ttctaacaat tcatttgaaa ttgattcatt cttgaatact
    65581 tgctgaagaa aagaacgctc attaggtgca aaacctatgt tgaattcttc aattaattct
    65641 aaagacaacc cacgactttg caaatattct aaagctggct gtccagcttt tgtatgcaat
    65701 agcatgtgat gatagatttc cgctgctttt tcatgagcag caatcagttt ccccgtagca
    65761 gattcaggat ttcggacagc tatagtacgc tgacgccatt gatcttctaa cggtatctgt
    65821 tcgaagtctg ccacttttac cactgcttct ggaaaactta gaccttctag ttcttgaaga
    65881 aaagtaaaca cgtttccgcc tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct
    65941 gcaacagaaa aagacggtgt acgttcttca tgaaaaggac acagccccaa gtaattttta
    66001 ccagactttt tcaactggac atattgtcca atcacctcaa cgatattcgt ttgactgcgt
    66061 actgtttcga taacctcttg aggaatccgt tgagccattt tttcaccccc tgctctattg
    66121 atatcttttg ggtttaacag aagatatttc aggagaataa ccggtaaaaa atcgcactaa
    66181 ctgaaatcag tgcgatttta aaggacacaa ttatacatgt ttgattgtat catatttcat
    66241 tgctttttca agtataacac atttctatct cattaagcat caatttgcta ctcttttcag
    66301 taactgattt tgaatatcag ccttccagta caatactcga agaacaatat ttacgagcat
    66361 gaatacaaag aagtatccta cgctctctcc caaccctaag tttacttcca aaattccatg
    66421 gaacagcatt gcagctacat atatccctac gatcgtcgtt actgctagga agatgcgcaa
    66481 tgggttgaag ggataacaag cttttacaac tgccatgcaa ctgatcccaa tcagcaagta
    66541 atacatcaaa gtagtagttt cagcatttcc ccatgcgaat gtttttccaa gtagatacac
    66601 cgcaatgata ttcactacta caagcaaggc atttggtaaa gcattaataa gtgctgtagg
    66661 caaataacgg taagtgattt ttcttttatc ttgttcaaaa gataaaaaga aggaaggata
    66721 cccttcaatc gctaaatcaa tcagcgtgat ttggataggg ataaacggaa atccaattgc
    66781 tgtaacggca catataatcg ataaaataaa tgaataaatc gttttgataa aaaagatgcc
    66841 tgagactttc gtcacattgt tgaccactcg gcgtccttca aacaggactt ctggcaatgt
    66901 agtaaaatca gagtccaaca ataccagatt cgcaatctga cgtgttgctc catcaccttc
    66961 tgccatagca atgctgcaat ctgcttctct taacgccaaa acatcattca caccgtcgcc
    67021 tgtcattgca accgttctgc cgctttcttt caattcattt accagcaatt tcttttgctg
    67081 cggactcact cgtccaaaaa ccgtatagcg atgagcagct tctcgcactt ccatttcttc
    67141 agtaatttga gaaagatcga catacgcatc ataattcggt aatcctgcac gtctagcgat
    67201 attggagaca gtaaaaggat tgtctccaga aatcactttc agatccacac cttcctcatg
    67261 aagataagct agtgtttctt gagcgttttt tcggattgga tcatcgattt caaacagagc
    67321 aaccggctca acaaatgctg gtttttcttc gttcaattgc tgatttggag cgatccccaa
    67381 cataagtacg cgatagccat tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc
    67441 ttccaccaaa cgttcaggcg ctcctacgta cacgactccc agttctggaa attccatcgc
    67501 gccccatttg cgatcagaag aaaatgcgac tttgtttgtc acatcatacc gattagaaag
    67561 ctcaaaataa tctctcatag cccgcatagt gatgttgtta tcactgcttt ctgccagata
    67621 cgtccccata atttctggga tggctttctc gtacagcgga tgtagtgctt ctacccgctg
    67681 gatactcatt ttcccttcag taatggtccc tgttttatcc aagcataatg tatcgacatg
    67741 ggccagcgtt tcaattgaat acatgtcttg aacaaggatt cgtttttttg ccagtttggt
    67801 tacccctgtc gttaatgcaa tacttattag caataccaaa ccctttggaa gcatgcctaa
    67861 caaagctgct gcagatgcaa taacagaaat tttgatagaa gcatcgcgga tgaacagtgc
    67921 ttccaaaaat agtatgatcc ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt
    67981 gcgaatcgaa tctacaagtt cagaacgaat agctttgtga gtctttgcct cgctagtcaa
    68041 gcggacagca taattatctg cacctactcg gataacttca gccatgacag aaccgcttgt
    68101 caaaaagctt ccagaaagca attcagctcc agtttctttg acaatcaaat cagattcgcc
    68161 tgtcaaaaga gcttcatttg cttctgcccg tccagatata acctgtaaat cggctggtat
    68221 ctgttctcct gctccgattt ttaccaaatc tcctaatacc agctctttag tagaaatcga
    68281 ttgttcttta ccgtcccgga tcactagtac ttctgattgg gaaacaatcg ataatttccg
    68341 tacaagattt cttgcatgta tttcttgata aattccaata acgatattga cgacaataat
    68401 tgctaaatac gccatgttgg aatacgcacc tacaaataac agacaaatcc caataccaaa
    68461 gttcagaaaa ttgaataacg tcaatatatt atcgctgaat atttgttttg tactttttga
    68521 tgcatcttcc tggtagtcat tttgctggcc agaagccatt ttctgaacta cctcttgctg
    68581 tgtaagtcca ttcattttct ttttctccat tttccgccaa ctttcaaaaa taatcacgtg
    68641 tttaagtcta gcgtgttcca agattaaaaa caacttgttt ttataaaatt tatagaaaaa
    68701 cacacgaatg attttacaaa aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt
    68761 ttttattatc aatctatctt tacttatatt gttcctccaa acggctcatc caccaaccta
    68821 gtgctgtacc ggctataaaa agaacaggac aagctagtac cccagcaact cccaatcccg
    68881 cgtaatcggt aggaatgatc ataatcgttg aagcaaaaac tacacctaaa atgaaatgga
    68941 atagcttgct atatgccttt gagaaaatgt aatccatgat ttttgacaat ccaagaacac
    69001 aaagaatccc accaattccg atcggcacaa tcacttcaag tcgtacttct ttaaatccgt
    69061 cagccatcgc tttatacaat cccatataca ccaaaaaatt agaagggctc aatcctggga
    69121 cgatcatacc caaaccaatc aatccgccgg caatcagcca tgttccaaaa ttctgatcga
    69181 cttgcccgtc aaataattga gcgccgtata ataaaaacaa ataagccaga acaaaagtaa
    69241 caaccatgat gatcacatca gaagtatctc ttcctttttt ccctgcttct ttccataacg
    69301 caggaacagt tccagcgata catccgacaa aaaaccataa tatcgttgtt tcatacgcac
    69361 ctaataaaaa actgactaaa aaagaaagta gaaagatgcc tgtcactccg cctagaccaa
    69421 caggcagaaa aaacaaaaca ttttctttga aattttttgt aaggtgggct aaaaaagaaa
    69481 tcagccgctc atacatgcca aagacagctg ctaatgcacc accgctgact cctggcaaga
    69541 taaatcctga accgataaac attcccttca caaaccgtaa catccagtct ttggttgtgt
    69601 accccacttc ttgattttcc attttttgcc ttttttccac tatttgcgta ctccttcttt
    69661 catttaattt tattcatgat tgaacatttc ctgctatttt acttaaagac tttttcatag
    69721 gtctctatta ttttttcatt cattttgaca atatcaggat aaaacatgtt acctccatta
    69781 tgatagagat agccgccatt gtaaagcaag gactggatcc gccaatatcg gtattgtttc
    69841 ccttcctcat ttcctaaaag tgggctcagc acatctttag aatacgcttc tgctaattct
    69901 actgtgtttt ctccgccatg attttttaca taggcaatat aatctttccc aaaattatat
    69961 gcttggacag ctgtccataa atcgcatcct tgtttctttg cttctactat catttccgcc
    70021 aaatatttga caccttgatc aatactgtca gctggattat caatgatctc agcttctcca
    70081 tgcagacttt ccgagctctg catgagatct gtcccttttc cttttgattc ggtcaatatt
    70141 atcgccttga tcaaattctc gtagttttcc atatgataat tttttgcagc tgttgttatt
    70201 tctatttgat agctttccac tcgttttacc gaacgataag ttcttcctca taaaaacaac
    70261 accgcaccaa taaccgtcag aatgatcatg taaaaaagaa tacggataat agataatcgt
    70321 tttcgcttca tttcatcacc tagttatttt gacatctttt tttatcttac tatttcttta
    70381 tcttcttggc tatttcttcc ttgatttctg tgtacgcctt aagaaaaaat gaattttcct
    70441 gtattttttg acatcttacg aaaatgatcg ttgtttttca gtaaaaacaa ttgcccaatg
    70501 actgatataa tcgttatact ttacacagta ggtgattatg tgaaaaaaga aaagaaatat
    70561 gcaaaaatgc cagatgggag cgaaatttac tatgaaaaga gcggtcaagg cttccctctc
    70621 tttttactgc atggcaatga cggcagcggc cgcttttttt cagaacaggt ccctgtactc
    70681 gaacgctact ataccgtgta tctagtagat agccgaggac atggtcgttc gacaaacgaa
    70741 gcatctatgt tgaattttca gttaatggcc gaggatctga atacgatcat gttgctggaa
    70801 aaaatcgatc aggcagattt tcttggattt agtgatggag caaatctagc actggtattt
    70861 gccagcagct tccctaaaaa agttcatcga ttgattttaa attctggaaa cacgcttgtt
    70921 aaaggcgttc gtttttctgc cagagtcatc agtaatattc attatgcatg ggtatggtta
    70981 ctctctttat ttcgcccaag tcttcgcaaa aatcttttag ttatcaaact tttgctgcat
    71041 gacatcgggc ttacagaaaa tgatttaaaa aaaatcaact cccccacttt gatcatcgtg
    71101 ggaaaaaaag atgtaatcaa gctaaaacat tctttgtata tagctaaaac tataccaaaa
    71161 gcttcctttg tgcttgtgaa agaacaagga catgaattag ctagaaaaga tcctgaacgc
    71221 ttcaatcgag aagttcttca atttctttct gaaacataac tattaggaat agaaggtgat
    71281 ttatttgtta aaaaatacca tacaatggct gaaaaaccac ctaggactgt tcaaaacaat
    71341 ctttttgatt tctgtcattg tcattattgt cggtgaattg atgtccatcg gtaaaactct
    71401 atctatccag caattaggag aaacgtttgc cactatacct gtatggaaaa gcggactaat
    71461 gctattgatt ggtcttatct ctgtgttacc tatggttggt tatgatatta ttttgaatcg
    71521 gatgcttgaa caaaagcaga atcctcgtta cctgtttgag acaagctggc tgatcaatac
    71581 gatcaacaat attgccggtt tcggcgggtt tgttagtgtg gggcttcgct ctgaactata
    71641 tggacaaaag aaagagagca gaaacgtgat ccaagcatta tcgaaagttt tcttgttttt
    71701 gatggctgga ctttctattt acagtctgct ttctttttta cttgtagtct tcacgccagt
    71761 tgctcctttt ttgaagcaat attggatatg gttgatcggc ggcggtctat attttcctgt
    71821 cgtcttttta tttactactt tcaaaaagaa aggattcctt ggtggtacct cacttaaaac
    71881 tcaaggacag ctattgctag tttcattgtt ggaatggacc ggtgtcctgt ttagtttcct
    71941 ttctgttggt tatttaatgg aaatccggat tgatctgtgg caaacaattc cattattcat
    72001 tgctgcttca gtgataggaa tcgtgtctat gattccagga gaaattggga gtttcgatgt
    72061 aatgatgatt atcgggttgt ccgctattgg tgtgccaaga gaaatagtcg ttgtgtggat
    72121 cttgctctat cgcctgttct actacatcat tccgtttttg attggaatcg tctttttctt
    72181 caaaaatatc ggttccactt ttgatcagcg ttattctggt atccctaaac aattagcaac
    72241 agaaattgcg cataaaatcg tggttgtctt attatacttt tctggaatca tgctagtact
    72301 ttctgccact atcccgcaag cttttacaga gtttcgctgg cttcatagtt tgaacccatt
    72361 gaaatttcat tttattatcc aatttcctag tatactattg ggatttcttt taatcattat
    72421 gggcagaggg atcgcagcac gtgtgaaacg agcatatttg cctacaatct tcttgattgt
    72481 tctagcttta ctttatgttt tattaagtga ttttagtttc acaccggtgg ttttcttgtc
    72541 tattctgctt ctgatcattc ttgcttctaa aaacgaatta tttcgggaac aattgatcta
    72601 ttcatgggag tggcgtacga tcgatggaat cattattggt gcactgtcct tgctttacat
    72661 cgttattggg gtatacaatc tgccggattt ccctcatcgg cgtcaccatt ttatttcctt
    72721 tttcttattt ccttctgaaa agatttggtt ttcgggattg ttggccatca tcgctgttag
    72781 tttcatgatc gttctatttg ttcatttcct tcaaggagaa aagaaacaga ttggcgaagc
    72841 ctttaatgaa gaaaaggccc tgaagatcct tacaacttat ggaggaaact ccgatagtca
    72901 attgatcttc ttaaaagata agcggatgtt tgcctatgaa aaagacggtg aaccaactgt
    72961 tcttctccaa ttcgcttgct tcaataataa atgtattgta atgggtgatc cttctggtaa
    73021 gaaagaagat tttccagaag caatcgaagc ttttatcgaa gaaacagatc gactatgcta
    73081 tttaccagtt ttctacgaaa caagcgaaga gattgttatg attttgcatg aattcggcta
    73141 cgatttcatt aagatggggg aagaagctta tgtagacctg aatagtttta caacttcagg
    73201 gaaaaaaatg aagggcactc gtgctgtctt gaatcggatc gaacgagaag gatttacatt
    73261 tgatgtctta caaccaccat tttctactga gcaaatgagt actttcaaaa atatctctga
    73321 taattggttg ggttcacgaa aggaaaaagg gttttcttta ggctttttct ctgaagatta
    73381 tctacaaaga gcgcctattg cagttgtcaa aaatacccaa gaagaaattg tcgcttttgc
    73441 aacgatcatg cctacttaca cgaacaataa agtaggaacg attgatctga tgcgatatga
    73501 ttctaaaaaa gcaccttctg gcagtatgga tttcttgttc ttgcatttgt ttgcctatat
    73561 gaaagaagaa catatccaat ggttcaattt agggatggcc cctctttcaa atgtcggaac
    73621 ttccagaaag agttttttac aggaaaggat tgcatacttg gtttacgagt ttggttctca
    73681 tttttattct ttccatggat taagagaata taaaagcaag tacgctacaa actgggtctc
    73741 acgttatact ctatattcta gagatagttg gattgcatat gttatgattg ctttgctgat
    73801 tattgataat gcgccagttg agcagacaca aggtagaata agtggtttga aaaaatggat
    73861 acgaagaaag tattaaaaac tgcataccga tagatgaaca ctctcatgat gaataaaaga
    73921 gactgaagta aaacgaaagt tcatgcttct acaatctctt cttatacaat tgaagaacaa
    73981 agagcggtcc aaacagaaat cctgtttgga ccgctctttt attttaaaca tttttcatta
    74041 ccaaaatatt cgagtcgcgt ttcttatgct tcgatctctg taacgatacc tgaacctact
    74101 gtccgtccgc cttcacgaat tgagaatgtc gttccgtttt caacagcgat tggatggatc
    74161 aagtcaacat caatcgtcac gttgtcacca ggcatgacca tttctgtatc ttctggcaat
    74221 gtgattgttc ctgtaacatc agttgtgcgg aagtagaact gtggacgata gttgttgaag
    74281 aatggagtat gacgtccacc ttcttctttt gtcaacacgt acacttctgc tttgaatttt
    74341 gtatgtggag taatggaacc tggtttagca agtacttgtc cacgttcgat atcgtcacgt
    74401 tggatccccc gtaacaacac gcctacgtta tccccagctt ccccgtaatc taacgtttta
    74461 cggaacattt ctacacctgt tacaactgct ttttgtgttt caggtttgat ccctacgatc
    74521 tctacctcat caccgacacg aacagcacca cgatcaatac gacctgaggc aacagttcct
    74581 cgacctgtaa ttgagaagac gtcttccact ggcaatagta atggtttatc tgtatcacgt
    74641 tctggtgttg ggatatattc atctactgta tccatcaatt ccataatagc agcttcagca
    74701 tctggatcgc cttgcaatgc ttttaatgcg gaacctttga tcacaggagt gtcatcgcct
    74761 gggaaaccat attcgctcaa taactcgcga acttccattt ctaccaaatc gatcaattct
    74821 tcatcatcga ctaaatcaac tttgttcaag aaaacaatca ggtattttac accaacttgg
    74881 cgtgacaata aaatgtgttc acgtgtttga ggcatcggac cgtcagttgc agaaacaact
    74941 aagattgcac catccatttg tgctgcccct gtaatcatgt ttttcacata gtccgcgtgt
    75001 cctggtgcat caatatgcgc gtagtggcgt ttttctgttt catattctac gtgtgcggta
    75061 ttgatcgtaa tcccacgttc acgttcttct ggagctgcat caatactagc atagtcttga
    75121 ggatttgcta ggcctttttt gcctaatact gtagtgatcg cagcagttaa agtagttttc
    75181 ccatggtcaa cgtgtccaat cgtaccaatg ttaacgtgtg gtttacttct gtcataatgt
    75241 tcttttgcca taatttacaa acctcctaaa taatatagat cactgaaaaa tttcagctct
    75301 caccttttta ttatagtctt tttttgacta aatcaaaaag aatacgtccg acttactttt
    75361 tgtaagattc gaactaagct tattatacgt caatattggt caaagtcaac taagagcact
    75421 cgtctgtctt atacgcgaaa aaagtacctt ttataaataa aaaaatgtgt tttttgagaa
    75481 aaacttcaag atagtcctta actttctttt gaagcaataa gaacaaaatg aggaaaagtt
    75541 taaaattcag ctgttgccaa caactttcaa tagacgaaat cttctatttc gttaataata
    75601 aggaaagagg tgaagtacat gaaaaaatta attggcgtac ttgtcgtttt aggcatattt
    75661 ctcggcggaa gttttgcagc ttatcattat ttttacggcg gcgaagctta ttatacaaaa
    75721 atcacgacga atggcgaaat gtcagctacc caagcagata acggagagaa attcacgact
    75781 tatacctaca agcaagcggc ttataataaa gatggtgaaa aaaaacaggt gacgcttcgc
    75841 gaagaaagag aacatccatt aaagatgaat gcgtatctta aactcaaagt caatcctcgt
    75901 aaaggtgtat taagctggga agaaataaag gcttctgaag tgcctaaaaa tgcggcagaa
    75961 aaaatcgata attagtaaat ggtcttaaaa ttttattaga taaaa
//
LOCUS       DAZKCH010000005        54202 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000005 DAZKCH010000000
VERSION     DAZKCH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.005"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(32..1423)
                     /gene="sufB"
                     /locus_tag="ACG84X_000363"
     CDS             complement(32..1423)
                     /gene="sufB"
                     /locus_tag="ACG84X_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFP9126270.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(1428..1898)
                     /gene="sufU"
                     /locus_tag="ACG84X_000364"
     CDS             complement(1428..1898)
                     /gene="sufU"
                     /locus_tag="ACG84X_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFP9126271.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(1885..3120)
                     /locus_tag="ACG84X_000365"
     CDS             complement(1885..3120)
                     /locus_tag="ACG84X_000365"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFP9126272.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(3117..4403)
                     /gene="sufD"
                     /locus_tag="ACG84X_000366"
     CDS             complement(3117..4403)
                     /gene="sufD"
                     /locus_tag="ACG84X_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFP9126273.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(4416..5189)
                     /gene="sufC"
                     /locus_tag="ACG84X_000367"
     CDS             complement(4416..5189)
                     /gene="sufC"
                     /locus_tag="ACG84X_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFP9126274.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(5386..6234)
                     /locus_tag="ACG84X_000368"
     CDS             complement(5386..6234)
                     /locus_tag="ACG84X_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFP9126275.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(6258..6944)
                     /locus_tag="ACG84X_000369"
     CDS             complement(6258..6944)
                     /locus_tag="ACG84X_000369"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFP9126276.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(6937..7971)
                     /locus_tag="ACG84X_000370"
     CDS             complement(6937..7971)
                     /locus_tag="ACG84X_000370"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFP9126277.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(8034..8290)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8366..8704)
                     /locus_tag="ACG84X_000371"
     CDS             complement(8366..8704)
                     /locus_tag="ACG84X_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFP9126278.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(8706..9062)
                     /locus_tag="ACG84X_000372"
     CDS             complement(8706..9062)
                     /locus_tag="ACG84X_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFP9126279.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(9068..10255)
                     /locus_tag="ACG84X_000373"
     CDS             complement(9068..10255)
                     /locus_tag="ACG84X_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFP9126280.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(10446..11291)
                     /locus_tag="ACG84X_000374"
     CDS             complement(10446..11291)
                     /locus_tag="ACG84X_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9126281.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            11525..12490
                     /locus_tag="ACG84X_000375"
     CDS             11525..12490
                     /locus_tag="ACG84X_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFP9126282.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            12867..13910
                     /locus_tag="ACG84X_000376"
     CDS             12867..13910
                     /locus_tag="ACG84X_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFP9126283.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(13972..14436)
                     /locus_tag="ACG84X_000377"
     CDS             complement(13972..14436)
                     /locus_tag="ACG84X_000377"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFP9126284.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            14682..15629
                     /locus_tag="ACG84X_000378"
     CDS             14682..15629
                     /locus_tag="ACG84X_000378"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9126285.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(15840..17912)
                     /locus_tag="ACG84X_000379"
     CDS             complement(15840..17912)
                     /locus_tag="ACG84X_000379"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFP9126286.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(17845..18222)
                     /locus_tag="ACG84X_000380"
     CDS             complement(17845..18222)
                     /locus_tag="ACG84X_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFP9126287.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(18351..18911)
                     /locus_tag="ACG84X_000381"
     CDS             complement(18351..18911)
                     /locus_tag="ACG84X_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9126288.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            19061..20353
                     /locus_tag="ACG84X_000382"
     CDS             19061..20353
                     /locus_tag="ACG84X_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFP9126289.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(20413..21531)
                     /locus_tag="ACG84X_000383"
     CDS             complement(20413..21531)
                     /locus_tag="ACG84X_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFP9126290.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(21545..22966)
                     /gene="arcD"
                     /locus_tag="ACG84X_000384"
     CDS             complement(21545..22966)
                     /gene="arcD"
                     /locus_tag="ACG84X_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFP9126291.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(23212..24333)
                     /gene="mnmA"
                     /locus_tag="ACG84X_000385"
     CDS             complement(23212..24333)
                     /gene="mnmA"
                     /locus_tag="ACG84X_000385"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFP9126292.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            24737..25336
                     /locus_tag="ACG84X_000386"
     CDS             24737..25336
                     /locus_tag="ACG84X_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9126293.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(25474..26760)
                     /gene="efmA"
                     /locus_tag="ACG84X_000387"
     CDS             complement(25474..26760)
                     /gene="efmA"
                     /locus_tag="ACG84X_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFP9126294.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(27031..27375)
                     /locus_tag="ACG84X_000388"
     CDS             complement(27031..27375)
                     /locus_tag="ACG84X_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFP9126295.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(27512..28657)
                     /locus_tag="ACG84X_000389"
     CDS             complement(27512..28657)
                     /locus_tag="ACG84X_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFP9126296.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(28837..29811)
                     /locus_tag="ACG84X_000390"
     CDS             complement(28837..29811)
                     /locus_tag="ACG84X_000390"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFP9126297.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(29891..30766)
                     /locus_tag="ACG84X_000391"
     CDS             complement(29891..30766)
                     /locus_tag="ACG84X_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFP9126298.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            30896..32803
                     /locus_tag="ACG84X_000392"
     CDS             30896..32803
                     /locus_tag="ACG84X_000392"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFP9126299.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(33344..36622)
                     /locus_tag="ACG84X_000393"
     CDS             complement(33344..36622)
                     /locus_tag="ACG84X_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFP9126300.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(36893..37438)
                     /locus_tag="ACG84X_000394"
     CDS             complement(36893..37438)
                     /locus_tag="ACG84X_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFP9126301.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(37450..38142)
                     /locus_tag="ACG84X_000395"
     CDS             complement(37450..38142)
                     /locus_tag="ACG84X_000395"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFP9126302.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(38161..38445)
                     /gene="macP"
                     /locus_tag="ACG84X_000396"
     CDS             complement(38161..38445)
                     /gene="macP"
                     /locus_tag="ACG84X_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFP9126303.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(38458..39021)
                     /locus_tag="ACG84X_000397"
     CDS             complement(38458..39021)
                     /locus_tag="ACG84X_000397"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFP9126304.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            39249..39911
                     /locus_tag="ACG84X_000398"
     CDS             39249..39911
                     /locus_tag="ACG84X_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFP9126305.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            40035..41231
                     /locus_tag="ACG84X_000399"
     CDS             40035..41231
                     /locus_tag="ACG84X_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFP9126306.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(41332..42708)
                     /locus_tag="ACG84X_000400"
     CDS             complement(41332..42708)
                     /locus_tag="ACG84X_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9126307.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(42745..43611)
                     /locus_tag="ACG84X_000401"
     CDS             complement(42745..43611)
                     /locus_tag="ACG84X_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFP9126308.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(43700..44725)
                     /locus_tag="ACG84X_000402"
     CDS             complement(43700..44725)
                     /locus_tag="ACG84X_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9126309.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(44743..45417)
                     /locus_tag="ACG84X_000403"
     CDS             complement(44743..45417)
                     /locus_tag="ACG84X_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9126310.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(45601..46494)
                     /locus_tag="ACG84X_000404"
     CDS             complement(45601..46494)
                     /locus_tag="ACG84X_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9126311.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(46568..48265)
                     /locus_tag="ACG84X_000405"
     CDS             complement(46568..48265)
                     /locus_tag="ACG84X_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFP9126312.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(48258..49571)
                     /locus_tag="ACG84X_000406"
     CDS             complement(48258..49571)
                     /locus_tag="ACG84X_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFP9126313.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(49571..53512)
                     /locus_tag="ACG84X_000407"
     CDS             complement(49571..53512)
                     /locus_tag="ACG84X_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFP9126314.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(53621..54079)
                     /locus_tag="ACG84X_000408"
     CDS             complement(53621..54079)
                     /locus_tag="ACG84X_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9126315.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
BASE COUNT        14990 a        11773 c         9814 g        17625 t
ORIGIN      
        1 tatatcaagg gttctagctc ctataacagg tttacccaac actgccttcc atctcataac
       61 tgatcaatcg attgagttcg actgcatatt ccattggaag ttctttggtg aatggttcaa
      121 caaagcccat gacgatcatt tcagttgctt cagattcggt caggcctcgg ctcatcagat
      181 agtagagttg ttcttctgag atttttgaga ctttggcttc gtgttctaaa gagacttggc
      241 tgttgtggat ctcattgaat gggatcgtat cggatttcga ccattcgtcc atgatgatcg
      301 tgtcacattc gatatgagag atcgaacccg cactgttttt ggcaaaggtt acttgtcctc
      361 gatagtttac ttctccgccg tcttttgaaa ttgatttaga gacgatagag ctagatgtat
      421 ttggtgcatt gtggatcatt tttgcacccg tatcttggat ttggtttgct cctgcaaagg
      481 cgatggagag catggtgcct cgtgcacctt ttccatctaa gtaaacactt gggtatttca
      541 tcgttgtttt tgcacctagg tttccgtcga tccattcaac ggttgcgcct tcgtatgctt
      601 ttgctcgttt ggttactaag ttgtacacat tgtctgacca gttttggatc gttgtgtaac
      661 ggcaatacgc atcttttctt gtaaagattt ctacgatggc ggcatgcagg ctgttacttg
      721 aataagtagg tgccgtacaa ccttcgacat agtggatgct tgctccttcg tcaacaatga
      781 tcagcgtacg ttcgaattgc cccgtgtttt ccgcattgat ccggaagtac gtttgtaatg
      841 gaacatcgac tttgacgcct tttggcacgt aaataaaggt cccacctgac catacggctg
      901 aattcagcgc tgctaatttg ttgtcggttg gcggtacaag ttttgaaaag tactctttga
      961 ataattcagg gtattctttc aaagcagagt cagtgtcagt aaagacgatt cctaactttt
     1021 cgaattcatc tttcatatta tggtacacga cttctgattc atattgtgcg gaagcaccgg
     1081 ctagataagc tcgttcagct tctggtatac caatcttttc aaatgtatct ttgatttttt
     1141 ctggtacgtc ttcccagtca cgagcgggtt tgtcacttgg tttttggtaa tatttgatgg
     1201 catcgaaatc gatgtctgaa aggtcggggc cccatgtttg cattggcatt ttgttaaatg
     1261 tttctagaga tttcagacgg aattcaagca tccattctgg ttcgcctttg attcttgaca
     1321 tctcacggat cacttcttct gtcaagcctt ctcctgtact gaaaaccggt tcgacatcat
     1381 cgtgaaaccc gaatttatat tcttctaatt ctggtacgcc catgttctca ctcctcttcc
     1441 ttgtggtaat gatggaaagc tgcggtacca tcgttttcca ttgcttttcc tagtgctttc
     1501 caggcaagtg tcgcacattt gatccgagcg ggaaatttag ctacaccacc aagcatagca
     1561 gcatcgccta attggtcggg atctttgact tcttttcctt ggacaagctg tagaaagtct
     1621 acagttaaat gttctgcttc ttctattgat tttccgatga cggcgtctgt catcatcgag
     1681 gcacttgccg tactgatgga gcagccactg ccgtcaaagg cgatattttt gatgattccg
     1741 tcttttacat cgacttgcaa ttcgatcaca tctccacatg tggggttgtt caattcgatc
     1801 ttgcttgtcg agtcagtcaa gcttccacga tgatgcggat gggaagaatg atccaagatc
     1861 acttgacggt ataaattgtc taatttagat agtcccatgt tggaaaaact cctttgttgc
     1921 catgattgct tcaactaaac ggtcggcgtc ttgcgttgtg ttgtagaaat aaaagctcgc
     1981 gcgagcagtc gctgatactt caaggtactt caatagcggt tgcgcacaat gatgacctgc
     2041 tctgacggct accccttcca tgtctaaagc tgtcgcgaca tcatggggat gtaacccatc
     2101 caaattgaat gcaacgactc ctgtccgaaa attcgggtct tgtggaccat aaacagtcaa
     2161 tccatcaatt gcttgtaatt ttggcaacac ataagcggct agttcttctt catatcgatg
     2221 gatattgtcc ataccgagtt tttgcaaata atcgattgca tggcctaatg cgatagcgcc
     2281 ggcgatattt ggtgtccctg cttcgaattt ccaaggtagt tctttccatg tactgtcgta
     2341 taattcgaca aaatcgatca tttcgccacc aaattcaaca ggttccattt cttctaacca
     2401 ttttcgttta ccatataaaa caccaatacc tgttggtccg cacattttgt gtccgctgaa
     2461 agcaaagaaa tcacagtcta gtgcttggac atcaatggcc atgtgcgggg cagattgagc
     2521 accatctact acgatgaccc cgccgttttc atggacaagt tcagctaatt cttgaacagg
     2581 attgaagaca cctaagacat tggatacatg agcaatggag acgattttgg ttttgtccgt
     2641 aatctttttc gctgcatcct ccatatccag gaagccttct tctgttagtt cgatatattt
     2701 caagacagca cctgttcgtt ttgccaactg ctgccacggg ataacattag aatgatgttc
     2761 catgtaagag agcactatct cgtctcctgc tttgatatag cggtcgccga aggttctggc
     2821 tacccaattc aagcttgtcg tcgtaccacg agtaaacagc acttctgctg tttcttttgc
     2881 atggatgaac gcccgtactt tttctcttgc ttgttcataa tcatgggtcg cgcgttctgc
     2941 taacgtatgg acaccgcgat gaacattggc gttatcgtgt tcgtaatagt acgctaatgc
     3001 ctggagtact tgttttggct tttgggtcgt cgctgcatta tccagataaa ctaaaggttc
     3061 atcattgacg tcttgaaata agataggaaa atcattgcgt agctttttag catcgatcat
     3121 ccattcaact tcccttcgat tacttcgact aattctttcc gaacttgttc tacagggatt
     3181 gctgttaaga cagaaccgag gaatcctcga atcactaagc gctctgcttc ttctttatgc
     3241 aatcctctac tcatcagata gtacatttct tctggatcaa ctcgtcctac actggcagca
     3301 tgtccagcag ttacttcgtt ttcatcgatc aaaagaatag gattcgcatc accacgtgct
     3361 ttatcagaaa gcatcaagac acgactttct tgttgggcat ctgcaccttt tgcccctttc
     3421 aagatgtggc cgataccatt aaaggtcaat gttccttttt ctcggatcac tccgtgttgc
     3481 aaaatatgcc cgatcgtatg aggggcttta ttggttactc gtgtatcgat tccttggatt
     3541 tgtctgcccg agctgattgc cacgattttg acttctgcgt gtgcaccttc tcctgctaaa
     3601 tctgagtcaa agtcagcgat cacatgaccg tcattcatga caccaattgc ccagtcgaca
     3661 gaagcatctc gtaaaatgtg cccacggcga ttcatataag aagtaatatt ttctcctaat
     3721 tgatctacgg ctgaatattt gatttttgaa ccagctttag cgatgacttc cacgatgata
     3781 ttacctgatg attttgctac ttgttctttg gttgtctgga aacgttccag ataagaaaat
     3841 tcactatgtt catctgccac gatcaacaca tgcttgaaga agtgctcatc ggatgcgcca
     3901 tcttgaatga ataaggactc gagtggttca tcgatcacga catttttagg cacatacagg
     3961 aaaataccgc tgttcataaa agctacatgg agtgcagtca attggtcttc gttcatgttt
     4021 actgcttttt tcatataata ttcttggact agttctggat attcgatcat tgcagtgaac
     4081 aagtcggtaa aaatgactcc tttttctgct aattccacag gcagttgttc aaaaatcgtc
     4141 catgaacctt gttggacaag cacaggattg tctttcattg catcaaatgc cggaatcgtg
     4201 cctgtttcac tgatggtttg tgtttctttc acatcaaata acgaccagcg atggaatttc
     4261 acccgatcga tatgcggcaa tggcagttca tctgctttcg ctagtgcgtc ttgacggaag
     4321 gttctcatcc aatcaggttc gcctttactt aaagaaaaat catttaccgc gtcaagataa
     4381 tcgagccagt ttttttcttt cattcttgct cccccttacg cttcttcttc tttatagtcg
     4441 attcctaatt ctttactgat accagcgtag ccttctgctt ccagacgttt agctaggtca
     4501 gcattccctg tcatgactac tcggccttcc atcatgatgt gaacgacatc aggtgtgata
     4561 tagttcaata atcgttgata gtgggtgatg atcaatgcac cgaaattgtc tccgcgcatt
     4621 tcatttactc ctttagcaac gactttcaaa gcatcgatat ccagacctga atcgatttcg
     4681 tctaaaattg caaatgtagg ttctaacatc aacaattgca ggatctcatt ccgtttcttt
     4741 tctccgccag aaaaaccttc gttcagataa cgttcagcca tttcttctgg catatttagt
     4801 aaagccattt tttcatctaa ctttttcaaa aatgccataa cagaaatttt gtcgttttca
     4861 tcacgtttcg cattgatcgc tgcacgcatg aattccgcat tcgtgatacc tggtatctca
     4921 cttggatatt gcatagctaa aaataagcca agtcgcgcac gttcatctac ttccaagtct
     4981 aaaacatttt tcccgtcaaa caaaatttcg ccttctgtta cttcatagtt tggattgccc
     5041 atgatagcgg cagataaggt agattttcct gtgccgttag gtcccatgat ggcatggatt
     5101 tctccggttt tcattgttag gtttacgcct ttaaggattt ctttttcctc gatcgacaca
     5161 tgtagatttt ttatttctaa gacagacatg cattataccc ccaaattctc tttcgttctc
     5221 actcatttta gactaattga gaatgaagcg caatgacctt ccttactaaa atcaaatatc
     5281 ttttatttat tattaaacaa ttttgatttc taaattagaa taggtataaa aaagatgaga
     5341 aataagccat tacagactta tttctcatct tttttgttcc ataccttatt ttgcatcagc
     5401 ctttactggt ttaacagagc cgccccattt gtctgtgatc cattcttgga cttctttgcg
     5461 gtgaagcact tcaatcagtt ttttgatttt gtcactgtct tcatcacctt tacgagtcgc
     5521 aataatattc acgtaaggag agttgtcctt ttcaagcaat acggcatctt ctaatggatt
     5581 caaccctgcg ccgtaagcga agtttgcgtt gattgcaact aggtcacctt catcattttg
     5641 gtacgtagaa gctaaaagtg atgggtcgat cgtatggttg aacttcaagt tcttagggtt
     5701 ttcttcaata tcatcgaatg ttgctgtttc cagatctact ccatctttga ctttgactaa
     5761 gccagcatct tgtagaattg tgatgatgcg tccccagtct gattcagaat ttgaagtaat
     5821 gattgttgca ccatctttta attcggaaac atctttgact tttttagagt acaagcccat
     5881 tggttcgatg tggacagcac cggcattgac aaagtcatat cctttttctt tgatttcttt
     5941 gttcaaataa ggaatatgct ggaagtaatt ggcatcaatg tcgccttctt ccaaagattg
     6001 gttcggtaat acatagtcat cgaatttgac gatttcaaga tcgattcctt catctttcaa
     6061 taatggtttc acatgttcca aaatctctgc gtgcggtgtc ggtgaagcgc cgactttcaa
     6121 tgtcgtgtcg tctgctttat ttgctgaatc tttgctgtcg ctgttgttac cgcatgctgc
     6181 taatcctaca gtcagcaaaa gcgctgctgc aaatccaaaa attttctttt tcatatccta
     6241 catcccccta tatcctatta tcttttgtct gttttcttag ttaagaaatc accgattcct
     6301 tgaacgataa atacgattag taaaataatt aaagtcgcaa cgaatgtcac tgttagatta
     6361 ccacgctggt agccttcctg ccaagcaaga cctccaagtc cacctgcgcc gatcgcgccg
     6421 gccatcgcag taaatccgat catcgagatc gttgtaactg ttaatccaga aatcaatgcg
     6481 ggaatacttt caggtatcaa gaccttccag atgatttccc agtaacttgc tcccattgca
     6541 tctgctgctt ccagtacacc agggctgact tcacgaaaag caatctctac tagacgggca
     6601 taaaatggtg ctgcggataa aacaagagct ggaatggctg cttgcgcacc tagcatagtg
     6661 cctacgattg ctttagtaaa tggaatgatc aaaaccatca ggatcataaa tggcgttgac
     6721 cggaaaatat tactgatgat cgatacgatt ccataaatga ttcgagcata cggtttgttt
     6781 ttgcgtccaa tagagtaaag gatcaatccc aaaactaatc cgatgatcgt cactaagacc
     6841 attgagatta atgtcatata tagtgtatca aggatagcct gattcatcgt ttccgggttg
     6901 atttgtttaa aatctagata tgtttctgaa aagcttttat ccacgatgga tcacctcaat
     6961 tcctactcct tgttctttga tgaacacttc tgcttgatct aattctttgg tttcaccagt
     7021 catcaagaca gtcaatgaac caaaggaacc ttctttcact tgtttgatct ttccatacac
     7081 aacgttgaca tcgatgttat agcgtcgaat cgcttgggaa atgactggct cgttggcatt
     7141 tctttcgcta aaggtcaaag ttgccaaacg gccgcttgga ttttctttga tgagttcagc
     7201 taatagttct gtcgaatcag cttctggttc gatgtcttgt tgtacaaagc gtttggttac
     7261 ttcttttttc ggttgtctga agacagtcaa tacgtctcct tcttctacga ctttccccaa
     7321 ctccatcaca gcgactttgt tgcagatttt gcggatcaca ttcatttcat gtgtgatcaa
     7381 gacgatggtc aaattcaatt tcttattgat cgctaacaat aagtctaata cttcttctgt
     7441 tgtttgcggg tccaatgcgc tagtagcctc atcacaaagc aggatctcag gatcatttgc
     7501 caatgctcgt gcgataccga cgcgttgttt ctgtccgccg gaaagttgtg aaggatatgc
     7561 ttgtccgcgt ccttctaacc cgactaaacg caacagttct tctgcccgtt ctttacgttt
     7621 gctctttggt acgccagcta attccagcgg cagctggata ttttcaagta cagttcttga
     7681 ccataacagg ttgaaatgct ggaagatcat accgattttc tttcggaatg tacgtaattc
     7741 tttgtttttt aattttgtaa tatcttgatc gtttacgatc acttcgccgc tcgtgggaag
     7801 ctcaagtcca ttcaggagac ggactaatgt actttttcct gcgccagaat agccgacgat
     7861 tccataaata tccccttttt caacgtttag tgaaacgtca ttgacggctt ggatgtttcc
     7921 gtttttccca ttgaatgtct ttttgacatt cgttagttgg attaatgaca tgccattcac
     7981 atctttctct tataattttt caaacaaaaa agccttcgcc ctcttgcctt aagcaaaagg
     8041 acgaaagctt gaacttccgt gttaccacct tgatttaccg ttacttcgca ataacagcct
     8101 cttccagtac ttggacttag cttctttccg tatactgtcg cgctgtaacg ggcactcccg
     8161 tagtaagttt gcttacgctc gcttactctg ctctaagacc atcttccatc tcattttcgt
     8221 tacccatttt cagcaaacag ggctctcttc aaacgtccgt gacatgtact cttcttttca
     8281 aagctttctc gtttcatata ggattgctta tgattatagc aactggaaga atcagtgtca
     8341 acttttttca agtgattttc tgattttata attcgtcaaa ttcttttgga tcaacatctt
     8401 tgaaacttaa gatccacgca ttcatttcat ctgaatcatt caagatattg atatcttcac
     8461 cgattttatc attaacagaa gaaactgtac ccgttagcgg gctggcaaat tcattgaccg
     8521 ctttttccgc ttcaacttcg atcagaggtt catctttttt tagcgattgt cctgcttttg
     8581 gcagattggc aaacgtgatg tctccaagtt cttcttgcgc ttcatttgtc aaaccaacac
     8641 agtattcttt tccattaaat aagatccaaa ggttgtcctt tttcttcaaa tgcttgcctg
     8701 ccattttata tcagttctcc ttcataaatt ttttcattga atccaattgc aacaagctgg
     8761 tcctctcgta agatcagtgg tcgcttgatc agcataccat ctgtcgataa gacttggctc
     8821 gcttttgaag ccgtaaactc gcctacttga tctttcagtc caagttcccg atatttcatc
     8881 ccgcttgtgt tgaacaggcg acggattggt acttgactcg tttctagcca agtctcaatc
     8941 gttgaggcct tcggtacttc tttgatcata tcaacggttt gataactaac gccatgctgg
     9001 tctaaccacg ctttggcttt tttgcatgtt gaacatttcg ggtaccagta aaaggtgtac
     9061 aattttctta cctccttgaa gatcttgcag gtgcttcatt ttggtatctc atcgataata
     9121 tcaacccgat accgatcatg ttccctaaaa tcgaggatcc tccctgacta atgaaaggca
     9181 atgggatccc tgttaaagga agtaatccga tatttgctcc aatattctca aagacatgga
     9241 acagcagcat catgatcaaa ccgcttgcga tataggcgta aaattcatta ttcgtatcga
     9301 aacacacccg aatcatacga tagattaaaa taaaatacaa gaaaatgacg aatgcaccac
     9361 cgataaagcc gaagttttca ccgataacgg taaaaatcat atcggactca cgaacaggca
     9421 catagatatt gcttacgttg aatcctttac caaacaagcc accggtacca attgccaaaa
     9481 gtccttgggc cggctgataa ctcattcctg acgtatcatg gaaagggtcc agccatgaat
     9541 caatacgtgc aaactgataa gatttgaatc caactttata aagcaagtct cttccgcctt
     9601 cagtcgtaac caagaagatc gttcctgctc caacgactac tgccaagatt actacaggtg
     9661 cgatgatgcg ccaagagatt ccagacatca ggaaaatccc gccaaagatc gcaagaaaga
     9721 caagcatcgt tccaaagtca tcttgggcca tgatcaatgc taaaaccggt attgtcacga
     9781 tcaagagctt cccaatcagc caaaagtccg atttcatcgt ccgttctttt acttgcgtat
     9841 tatgtttagt tacgatcagt gccatcatca agatgtacgc aatcttcatc aactctgctg
     9901 gctggaaagt aaacgcaccg aatcgaaacc agtttttaga ccctgttgaa gcagctaaat
     9961 tctgatcata gaatttgagc aagagtccca ttaccactaa ccccaaacca taaaggtaag
    10021 gagtcagttt ccagatccat ttggaattca aatgcatgat gacaacgatt gctgccgctc
    10081 caactaaata ccagacaact tgcatcccta cgcctttcaa gactgctgga ttgttcggat
    10141 catggctaag tgctacatat aatgagagca gaccaatcaa acataacaga aagactggta
    10201 aaatcacgcc ataatcaata cgattatcgt tcgaagcttt taattttttt tccatgtttc
    10261 atcccttttc ttaaaaacca tactgctgat tattatagcg gtccagttag ataatggaaa
    10321 gtctttccat agacatttgg gaaaaattaa ctttccgttt gtgcagttgc ttgagcaaat
    10381 gcagtacaaa agcctactgc ttatctttag tgtatcatag aacttttttt gatacatgca
    10441 attatctacc agctgagatt ctcctcgctg tgagaagttt ctgtgctttc attgtatcga
    10501 aggatctctt cggcaatctc tagcagctga tcagaaacca gattggttcg ttggatgaaa
    10561 taaaaatatc gatggaaatt caacggagtc attggcacat tttctggaac agagcgctta
    10621 gacaaaatcg agcgaccgat tccttccttc agcaacgcaa caattacatc gttacttttc
    10681 acgatcatct tcttatcttg gatattcatc tcttcaaaat aacgctgcgt gtaatgaaaa
    10741 acaccagagt ttgcttctct tacaagccac aatttgcttt ttgggtcccc agcgatgact
    10801 agctggtctt ccatcaaaga gtatctttgt acgccggaag tctctaatgg cttttcgata
    10861 aaaccaaaat cggattcatg tttcgctact tgttctaatg attcatgaga attcgtgatt
    10921 tcgatctcaa aatgcacttt aggaaacctt ttgatcagat gtttcatcaa ctgaggcaaa
    10981 agatagacag caaaggtgtg ggaagcaacg atccgacata cttcttcttc attttgttca
    11041 ttgagcaatt tttgctgagt ttcttcccat tcttctaaca aaaccagtgt ccgttcatat
    11101 aataagtcgg cttgcttagt tggaagcatc tcttttcttc cgttacgttg aaaaagatcg
    11161 atattcaatt cccgctccaa ctgtttgatt tgattcgaga ctgctggttg agataaaaac
    11221 agtacttctg ctgctctgga aaaatttctt gtttcatata ctgctcgaaa agtcgttaat
    11281 aacttaaaca tggcaccact tccataactt tttatgataa ttactataaa aactatttga
    11341 tttaaatata caaaaaacca tctataatag aaatgtacaa caaaacagtt gctgatccaa
    11401 ctagtaactt agatgaagac aatcagctgt ctgcttgctc gtaatcatac attcctattc
    11461 attttacaat gtattcgttc atcttggtac taaaatctat taaataaaaa ggagaatatt
    11521 atatatgaag aactttttga aaattattcc gatcccgatc tgcgggttga tccttgggtt
    11581 agcttccctt ggaaatctgt ttaaagacta tcaccatgtt gctttaggca atctaactgg
    11641 cggtatctct atgattctta tgatattcat ttttgttaaa ttgtttatct tattcgaaca
    11701 cacgaaacaa acgttgcatg atccaatcat cgcctccgtt tcaccaactt ttacgatgtc
    11761 actcatggtt atttgtactt attttgtttc atatgaaagt attgcaccaa ttgtcaaatt
    11821 catttggctg tgcgctgtta tcttccaagt gatccttgtc ttttatttca attatcacca
    11881 tgttatcaaa gctgatcttt caattgaagc aatttatcca agctggttta tcatttacgt
    11941 tggatttggg gtcatcactg taactgccgg gaacttcttc ccacttattg gaaaaatttt
    12001 cttttggatt tcattgatct gctatgcgtt cttattgccg atcatcatca aacgtgtctt
    12061 tttcgtaaga aatatggctc atccgacacg tccgctgatt acgatcgttg cagcacctgg
    12121 ttctctttgc ctaacaggtt atcttaaaaa ctttgctgaa cctaattttt atcttgtcgt
    12181 agcattgttc gctttatctc aagtattgta tttcgttgtg ctgtctatgc ttccacgttt
    12241 gttcaagctt cgtttttatc caagctatgc agcctttaca ttcccgcttg ttatctctgc
    12301 aacagctata tttactactg ttcattactt caacagttta ggtatctata gtagcgtatt
    12361 ggatttctta aaagttgcgg aatgtctgtt tgcaagtgta gttgtcttct acgttcttgc
    12421 tcattacgta cgtttcttaa ttaaagaaca tagcaaacat ggaaaatttg tttctaaaaa
    12481 aatcgcttaa taatcgattc aataggttgt gaaaaagctg ttctgcatca agtaataaga
    12541 acggccaaac aaaaacagct gttcatgttt ttgtactggt tgggcttatt accgcagatg
    12601 caagcttttg aacaccgttt accaagaggt cgtaaaagaa gtggtcagct tcaagaaata
    12661 agaaggaatt tacgaaaatt gcttctcaaa tttttgtgaa atttcggctt atttccgtag
    12721 aagctacttc tggaacaccg tttattcgaa acaagaggtc gtacaagact tttgtcacga
    12781 cctcttgttc ttttgtcaaa atactggttt agtgctacta tgttcgagta tgcttttagt
    12841 atttattgac gaaaggaacc gatcaaatga aatcattgtc acatccaata aaatctgtaa
    12901 aggattcagc ggtccgcgaa atcttacccg gtttactgct ttcttttgcc atcgctgcct
    12961 tcagcaggct tcttgctatt tatctgccac agttaggtgg agcgactatt gctattttat
    13021 tgggtatttt attaggaaat acttttttta aacagcctgt tctagcaatc ggcacaaaat
    13081 ttgctgaaag caaactatta gaattctctg tttttttact aggtgcaact gtcacagctc
    13141 aaacgattgc tcaaattggt gtaaaaggaa ttgtttttgt gttactgcaa atgtcagtca
    13201 ctatcatcgg tgcttacttg attggtaaaa aactgcaatt cagcgatact tcttctttga
    13261 tgatggctgg aggaaacgct gtttgtggtt cttctgctat tgcttcaatc gccccttcca
    13321 tccatgcgaa agaggaagaa aaaggacaga tcatcacact agtcaatcta ctgggtactg
    13381 tgatgatgtt gactctccct tttcttggat tacagttgtt tggtggaaat ctcattgaaa
    13441 aaagtgcact tttgggtggt acactccaat ctgttggtca agtagtcgct ggggcaagct
    13501 tacttgacaa ttctgttgtc gaattcgcca tgctatttaa gattctacgt attatgatgc
    13561 tcgttgttgt tgtctatctg tttgaaaaat tcatgcacaa gaaacaacca gctctgtttg
    13621 aaacgccaac tgatacgcag aaaaaacgaa aattaccgct tccttggtat gtattagggt
    13681 ttgtgatctt ttgtttggtc aacagcttgt tttctttacc tgtagttatt gaccaatcgg
    13741 cacattttat cagcagctgg tttgagatca ctgctttagc ggcaattggt ctgcgtttag
    13801 actttgcaaa attcatgaaa gaaggtacac gcttcttatc ttatggatta gctgtcgggc
    13861 ttctccaaac agtgatggct ttactattta tttggctgat caaagtttag aatgaacatg
    13921 aaaaaacagt tgtgattctc gcatggaaca atgtccgaat cacaactgtt tttaattttg
    13981 cagatatcct tctaacaaca acaattggcg tttgatttca accccatcta ttgcgtttcc
    14041 catatatcct gtcagttttc cattttgccc gatcactcga tgacaaggaa taacgattgg
    14101 caatggattg gttcgatttg cctgcccaat cgctcgcaca gctttcggac tatcaacagc
    14161 aacggctact tctttatacg ttcggatttc tccataagga atggtcgaca aagctttcca
    14221 gacattttgc tgaaaaggcg tacctctctt tatagataaa ggaacatcaa attcttttct
    14281 ttttcccgca aaatattctt caaactgttc ttgtgtgcgc gttaaaattc gctgattcgc
    14341 tgattcgctt tctgaaattg gctgaaaaga tacagcagtc aatccggatt catctgcatc
    14401 taaccataaa aagccgatag gtgtgtgtat tttcattttg tttgctccta gtcaatagac
    14461 tggaacttcc tcctttttct ctatccaaaa ctacttgcca actaataaaa attgttctta
    14521 aaagtttgat aaaccgagga aacatggtaa actaaatacg ttagtttaca aaaagaatac
    14581 ctgttctttt acgtaaaatc aaattttaaa ggtgttattt aaggtttatt aaattttgaa
    14641 tgtaaaccat atataaacat acgattgaaa ggatagaaac gatgaaagta tcaattgttg
    14701 tcccatgttt taatgaagaa aaaactgttc ctcttttttt tgatgaggtt gaaaaattca
    14761 aaggtgccca tgagttcgaa tatttgttta ttgacgacgg atcaaaagac ggtacgttag
    14821 cagcaatcaa gaagctagcc tcagcttatc cttatgtccg ctttgtctca ttttccagaa
    14881 attttgggaa agaagcggct ctgtacgctg gattgcaagc ttctacagga gatttagtga
    14941 ccgtgatgga tgttgatctg caagatccgc ccgaactgct tcctgagatg atcaaccgga
    15001 tcactacttc tgatatcgat tgtgtcggca cccggcgttc gactcgtgaa ggcgagcctg
    15061 cgatacgcag tttctttgcg aaaaaattct accagttgat caataaaatc agcgatacag
    15121 aaatggtcga tggcgctcgt gatttccgct tgatgactcg tcaaatggtg gatgccgtcc
    15181 tagaattaac agaatacaac cgattttcaa aaggattatt tagctgggtc ggatttaaaa
    15241 cagaatatat ttcttatgaa aaccgcgaac gtgtggctgg cgaaacatct tggtccttct
    15301 ggaaattatt caactactcg attgatggta tcgtgaactt ctcggatgca ccgttaacga
    15361 ttgcttcatt tatcggcgct ttgtcttgtg tcggttctgg tattgcaatt ttgttcatta
    15421 ttttgcgggc attgttgttt ggtgatccta catcaggatg gccttccatg gtctcgatct
    15481 tcctgttcat tggtggaatc caattgttat gtcttggaat catcgggaaa tatattggga
    15541 aaatcttctt agaaacgaaa cagcgtcctg tttatatcat aagagaaaca gaaaaagtga
    15601 agccaaatga attgaagcct caccaataat atacgtcaaa tgaagtaaac atttttttaa
    15661 atgaaaaagg actgtgacaa aagtcttgtc acagtccttt tttccgaata aatggtgttc
    15721 cagaagtagc ttcttcggaa ataagccgaa atttcacaaa aatttgagaa gcaattttcg
    15781 taaattcctt cttatttctt gaagctgacc acttctatca caacctcttt catatcttat
    15841 tacttcttca ttgctgcttt tagtgctgct gctaatgggc tttcttctgg ttcttctgct
    15901 tgtgcatatt ttttcagcaa gcgtcgttct tcatgtttgg tcattttctt cttctgctct
    15961 tttttatcaa gcaatttttc tgtcgttcca tcgtatttac aacggaaata agcaccgttt
    16021 ttaccttcga tgatttccat tttccggtga cattgcgggc atcgatgatt agagactttt
    16081 ggatcttttc ttctgcggta gttgcaatct gaattggtgc agacatagat tttgccgtca
    16141 cgtgtgtttt tctcgcgcag attggcccca cattctgggc atttcttttg ggtaatcgag
    16201 aaatcttgat attcttgttt gcttgatttg atctcattca ccaagcgttt tgtttctttt
    16261 tcgattccat tcaagaaggt tcctgcttgt ttctttcctg cagcaatagc ttcaaggtct
    16321 ttttcccagc tttctgtcaa atctggtgtt actaaagagg gatttaccaa tactaataat
    16381 tgcttacctt taggagatac ttgcagtcct tgaggggtac gttccatcag ttcagatttg
    16441 attagtttct cgataatctc tgcacgcgta gctggggttc ccagactgta tttttccatt
    16501 tgaccaagca agcttgcttc tgacaatggt ttaggcggtg cagatagttc ttttttgatg
    16561 gcgaaatcgg gattgattct cattcctttt tcccatttga ctgtttccgt ctcagtttca
    16621 gtttcgcctt tccatcctgc ttggacgaca cgattttgcc gaaaaatgaa tcgttcttta
    16681 ccaaattcaa ccgtaacttt tgtttggctg actttatggg gttgagcaaa cagtcctaaa
    16741 aaacgagaga caatcatttg atagattttt cgctcttcat tacttaattt ttcataacgt
    16801 gctctgtttt cagttggcaa aagtgcatgg tgatcggtca ctttactgtc ttggaatact
    16861 tttgtctgtt ggacgatggc tccgtttttc aaatactgct tgacctcagg agcaaagtcg
    16921 ctgactgctt gcaatcgttc tttcatcgta cttttcatgt catttgtcag atatttgctg
    16981 tctgtacgcg gataagtaac gatcttatgg gtctcataca aactttgtac aagacttaat
    17041 gttttctttg cagaatagcc atagcgttga ttggcttctc tttggatctc tgttaaatca
    17101 taaggcaatg gcgcagattc cgtttttaat ttttcttgga cttctgtgac agttcctttg
    17161 cttgtactga tcaattgaac aagtttttgt gcttcttctt gtgtttttaa agcaaattga
    17221 tttttttgaa gcattttggc ttgttctttt ccagcttgca acgtgatcgt gaaatacgtt
    17281 tgtggacgga actgctcgat tttcttttct tggtctctca ctaatgctag tgtcggtgtc
    17341 tgcacacggc ctgctgataa attatccgcg tacttcacag ttaaggctct ggtcacattc
    17401 aatcctacca gccagtccgc ttttgcccgg gcaagagcag attcatacaa tgcatcatat
    17461 tctttcgcag gtcttagttg cttgaatcca gttttgattg ctttatctgt ttgagaagag
    17521 atccataacc gcttcactgg tttattgaaa tgcacatact ctaagatcca gcgagcaaca
    17581 agttcccctt ctcttccggc atctgtcgca atgactgctt ctgagacatc ttttcgctga
    17641 gccagctgct tgattgcttt taattgatgt cctgttttag gaagtggttt gattcctagt
    17701 tttttaggga tcattggcaa cgtgtccatt tgccagctct gccattcctt attcagatct
    17761 tccggcattt tcaatcctaa taaatgacca agggcccaag taacgatcac cttgggtcct
    17821 tcataataat ttttgtgctt ttgattagca ccaagcacct tgcttaggtc tttcgcaacg
    17881 cttggttttt ccgctagaat tagttgtttc ataaaattcc tttctgcttt ctactgtgat
    17941 gggctgatga tttttcaaca acgcaagtcc cttgtattgc tgtaaatcat cgtcacactc
    18001 ttcacaccag cgctcatctc cgtcattcca aaaggcgctg agaaagttac tttttgcatt
    18061 gatatattca taattttgat ggatttcgtt ccattgtttt tcgtacgctt gtcgtgcttc
    18121 ttcgaaagac tcgaatgttt cttcttcttc aatatcttct tcccagtctt caaaaaacca
    18181 ccaaggctca ttgtccccga acatggtaat tacttgatac atactcgtgc tccttctttc
    18241 agcttttcta gactcatctt agtcactttt caagaaagtt gcaagaattt tctcttataa
    18301 aagggtcatt taatgaacat cttaaaattg ttacaaatga atctgattgt ttaaggcaaa
    18361 gtagcgataa agttattgat catccaaaaa tagctgtctt ctggatcgat tgttggttct
    18421 tttgtaaagt atcctaaaaa acgtaaggaa agataaccgt ggatcatact acgaagttcc
    18481 ctgcttcgat gaactttttc ttctttcgtt aattgaaaag cctcaaatat ctgcaaaatg
    18541 atctgattcg tttcatggat tccatctaat aaaacagctt cattggtatg cggtacactg
    18601 atcagtaact catacactgc ttgatttgaa aaagcaaagg atcgataagt ttctgcatag
    18661 atctgcagtg cttcctgacc actttttccc acaagagccc gtcgcagctg gtcattaagt
    18721 tcctgcagaa gtttcgctgt tagcgctgtt ttgacatcac gaatattttt gaaatggtta
    18781 tacagcgagg gagccttgat atccaagcgt ttggctaaat gctgaaaggt tatttgctga
    18841 acatccatct cttctgctag ttctcgaaag cagtcgatga ttttctcttg agacagattt
    18901 ctttttttca tttccatgtt tcctctcata aaataaatcc ttcactcttt cagtttacca
    18961 cgaaaaagaa agagaaaaaa gagactttca ttgataaact acatattgta gtttataata
    19021 aagagctgta gatgaaaatt ttcagaaaga aggagtctaa ttggctgcaa gaataaagga
    19081 aaaattattt aggaaaagag aaacttggga acaaaacttg tttgtcttat ggtttggaac
    19141 atttatggct ggtatcggat ttagtttagt catgcctttt atgtcacttt acatagatac
    19201 gttaggtaat tatagtacgt cacaattgaa cttttggagc ggattgactt tttcatctac
    19261 tttcttggtg actacgctta tctctccttg gtggggaaaa ttagccgacc aaaaaggaag
    19321 aaaattgatg ctgttgcgtg cttcattagg aatggcaatc gtcatttctt tgatgggttg
    19381 cgtgactagt gtgtatcaat tagtcgcatt gcgtctgctt caagggattt tttctggtta
    19441 tatcagtaat gccactgccc ttgtcgcaac tgggacgcca aaagaaaaaa gtggtcaagt
    19501 tcttggaacc ttagcaactg gttctgttac aggaacatta cttggaccgc ttcttggcgg
    19561 gatctctgct tcagcgtttg gctatcgccc tacctttttc attacaggga tcatcttatt
    19621 tttcgtcttc ttgttgagtc tgtttttcgt ccatgaaaaa tttgtcccag tgaaaaaaga
    19681 aaacatggtt tctgccaaac agattttcaa agacttgaaa tatccacacg tcgtcatcgg
    19741 tatgttcgtc acaacgatga tcatccaagc atccaacaat tccattagtc caatcatcag
    19801 tctgtacatt cgccaattgc tgcatggaca tgggaatgtt acgttgatca gcggaatcat
    19861 tgcttcgata cctgggattg ccactttgat agccgctcca agatttggtc gcttaggtga
    19921 caagattggg agtgaaagaa tacttgcgat tggtttgggt tttgcgattc tggtttatat
    19981 cccaatggca ttcgtcacga atgtttggca attagctgcc ttacgttttt tgattggtat
    20041 ctctgatgct tgtctgctcc ctgctgtcca agcattgatc acaaaatatt cgcctcatca
    20101 agctgctgga cggatcttca gttataacca atctttccaa gcaactggta acgtagtagg
    20161 gcctatgatc ggctccagtg tttccagtgc atttggttat cgcggcgtct ttctttcgac
    20221 ttctcttctt gttttggtca acttcttgct tgtacgacac aatacacaag agatccatca
    20281 gcaagaaact gcagaagaaa aagcttcagg agtctccata gcttcagggc actctccttc
    20341 tcatagacaa taagcgtaaa tgaaaaacac tgcttgaaca gttgtcacag actgtccttg
    20401 cagtgttttt gtttaggcct gttttttcaa gaactcagat aagaggaata atcccttttc
    20461 caaggtttct tttttacaac agtaacctag tcgggcatgc ttcggtaaat caaaggcact
    20521 tcctggtact aatagtactc ctgtttcttc taataaattg atacaaaatg tctggtcatc
    20581 ttcttcgatg gctaatttaa tgaaagaagt agagacgtaa ttgggagcga caagttcaac
    20641 tttcggttca ttggctaccc attgttttaa aatcacaagg ttctctgtaa tgatcttttt
    20701 gtttcgcgcc aatatttttt ctttattctt caatgcatgt acagcaagat catctgacag
    20761 gactccgccg caaatcatcg tgtagtctcg atactttcga aaaacttctg ccaactcagg
    20821 tccagtagct gtccagccaa tacgaatacc tggaatggag taggttttgg atagggaatt
    20881 ggttgctata cctttttcat agacatctac gatcgacaag aattcacctt tatccgttaa
    20941 aggcgcatat acttcatcta tcaatacata tgcatctact gtacgagcaa tttctgcgat
    21001 tttttctaaa gttttccgat ctagcaatgt gcctgtagga ttgtttgcac tattcaaaca
    21061 gatgattttt gtttcaggtt tgactaaggc ttctagctgt tctaaatcaa actgccaatc
    21121 ttcttcttcc ttcaaatgaa caaagtcaac agcggcacct aaagatttgg ggatgtcata
    21181 taattgctga taagtaggaa gcatcgaaac aacatggtct cctgcttcca ctaacgcgta
    21241 tagagctaaa agattagcac cagtcgctcc attcgtttgt aagatgtttt ccggatcgac
    21301 ggtttgataa agagaagcga cttcttgttt gaaaacatct gatccttcga tccagccata
    21361 gtccaatggt tcgtttttgc gtttttcgaa aaatttactt acgctagtcc catctaagcc
    21421 aacgagttcg tctaatgtca atgcttcgat cgagctttgt gcaatatcat ataccgcttt
    21481 cttttcccat ttatttagcc attcttctac accgaaattt gcgattttca tgtttctttc
    21541 ccccttatat cttgatccag cctacagcaa gcaacccgat tgaaagcagt gcggccacac
    21601 aaatcagccc aatcattact ttttcttttc ccgtaatttg atgtttggtt tcacgacaag
    21661 cgatccagta gaagcaaaaa ccaggaagat aggcaatact acataaaagg acataagaaa
    21721 atcctgctaa aatgatgccc atcaattcaa aaactacagc aatcccaccg atcactactt
    21781 gttttttgat tccttctttt aaagaaaact ggacttgata gatcccgaca agtagataac
    21841 aaatcaaaat tgccgctgta cataaagaat aggcaaattg ataggcataa tcagtaacta
    21901 agaaagtcaa taagaataga ttagtcaaga ttgcagtaac aactaacgaa taagttgggg
    21961 catttttttt attcgttttt ccccaacctt tcggcaacag accgtctcga gccatcaaca
    22021 tcgttgtttc tgctgggagc atcgtccaag acaaccaaga accaatgatc gaaataatca
    22081 agccgatatt gatcagcgct gctccccaat ttcccacgat tccttttaaa atatttgcca
    22141 tagcaggttg tgaaatagtt gctaactctt cttgagataa gacgccgtat ggcaagatcg
    22201 aagcaaggat atagataaac aataaacaaa gcagaccaat gatcgatgct tgctgggctt
    22261 ctgaacgttt cttcgcgcgg ttggctaaaa cacttgcgcc ttcgatccct acaaagaccc
    22321 acatcataac catcaaacaa cctttaatct gcaaccagat cgttccttgc tgccctgttc
    22381 cattcactag attatcagat acgttacccc aaaaatcagc agtgaatata ttcactttaa
    22441 atgcgataaa tacaaatatt aaaaatagga ataatggcac taatttacag atcgtcacga
    22501 ttgtattgat gacgctcgct ccttcaactc cattgtttac taataaagtc agaccccaaa
    22561 taaaaatact tgcaaataaa atagaaggaa cattttgtcc acctttgaat atcgggaaaa
    22621 attctcccat ggcgctcatc agcatcgttg caaaagcaac atttcccagc cacgcagaca
    22681 accagtaacc ccaaccactg atgaagccac ctaatttacc aaatgaagct tccgcgtaac
    22741 cgaaaatacc accatctaga tctggacgct tttctcctaa atgattcagc gataatacca
    22801 aagctaaaat accaatccca acgattatcc atgaaaggat cgctggccct ggagctgcag
    22861 aactagccag atcacttgtg atcccaaaca caccgcttcc gattgacgaa ctgacaacca
    22921 gagcaaccag tccccatttg ctaatacccg tcgatttctt ttccatttcc atcaccctca
    22981 cttataaaat tgaacaaatc acttgcaaaa gattcccttc tattttgcaa ctgctcttgc
    23041 ttaacaaaaa gcaactttat tcatattatt ggatattatg aactttttac acaagtattt
    23101 caagtataaa atgaataaaa attaatttta ttgcaaaaaa acagctatgc tatccaaaag
    23161 aaaaggtgtt tcttttgtta gccatagctg ttttgattca tttaatatcg cttaaacgta
    23221 ttgtaaaact tttgtttctt gatatgcgtg gtcgatcaaa ccaccaccca gacattccat
    23281 tccatcataa aatacaactg cttgtccagg agtgattgca cgtacaggtt cgtcgaatac
    23341 gacttctgca cgattatcat ccaataagcg aactgtcaca ggaacgtctt gctgacgata
    23401 acggaatttc gctgtacact tgaattcttt tggcattggt tcattcgtcg taaagtggat
    23461 ttcacttgca tccaagcttg tggcatacaa tgcaggatga tggaaccctt gccccacata
    23521 taatgtgttt gtcgctagat cttttcctac aacaaaccag ggttcttgcg aatctcctcc
    23581 gccaccgatc cctagtcctt gacgttgacc aatcgtataa tacatcaagc cagcatgttg
    23641 tcctttgact tcaccatcaa gagtgaccat atttcctttt tttgctggca gatagttgct
    23701 caaaaattgt ttgaagttct tttcaccaat aaagcagatt cccgttgaat cttttttctt
    23761 agcagtcgca aggcctgcgc gttcagcaat tgcccgtact tctgattttt ccatgccgcc
    23821 tagagggaac atcgtttttg aaagctgttc ttgtgataat tggctaagga agtaagtttg
    23881 atctttatta ttgtctactc cacgaagcat gtggaccacg ccgttttcat cgcgagtgac
    23941 ttgcgcataa tgtccagtag ctacataatc ggcgccaaga tccattgcat aatccaagaa
    24001 tgctttgaat ttgatttctt tgttgcacat cacgtctggg ttaggtgtac gtcctgcgcg
    24061 gtattcggct aggaaatatt caaatacacg atcccaatat tctttttcaa aattcacaga
    24121 gtaataagga atcccgattt gagcagctac tttcgctaca tccttataat cttccgtggc
    24181 cgtgcataca ccgttttcgt ccgtgtcatc ccaatttttc atgaatattc cgatcacgtc
    24241 gtatccttgt tcctttaaca aaagtgctgt tacagatgag tcgacaccgc cgctcatccc
    24301 tacgacaacg cgtgttttgc tgttgtctgt catgatatca ccatcatttc aattagattc
    24361 tgaaacatct acgagttgaa ggtcgcaact tttcagtatt ttacattata cgtcatattt
    24421 ctgaaaattt catcccttaa ttatcaagtc gtaaaaatac tgttctactg gacctattca
    24481 gtacacaaac atgatagtca accaaaaaat cactcatctt ttgagcattc gatataaaaa
    24541 attggcatac tcataaaaag ggccagcctt tcggcaataa ggaataattt tataaattgt
    24601 gaaaaactat ttttcaaaat tgcttcttat cgcttaaagc tgcacgtctc atttacaacc
    24661 ttttcttttt agatgttatg agttgctcag ataagtgatt ttgtttactc taagaaaaaa
    24721 gggaggcaaa agatacatga attactttat cagtgatatg cactttttcc atgaacgctt
    24781 attaggaaaa aacgactttg ctccgcggct ctttgcaaat gtggatgaaa tgaaccaaca
    24841 gttgatcact agctggaatg cagtaataaa agaaaccgac catgtttatc atctaggcga
    24901 ccttgctatg catccgcaat atgaaaaagc aaatgcagaa attttggaac tggtcactca
    24961 actgcaagga acaatccact tgatcaaagg gaaccatgac agtcgcgctt ttttccgtta
    25021 tttagaaaaa aatgatccta ggcttactga cggaagtccc aaattttatt tttatgatgt
    25081 aggtgccatc gttaaattcg accatcaaca atattacttg actcattatc cgatgttgct
    25141 cgggcctaac gacactatcc gcaatcttca tggacatatc catcattaca gcgtacctat
    25201 cgagaacgat gtcaatgtag gcgtagacgc accggaaaga gaactcttaa aggaaaaact
    25261 accatttggc actccgttat ctgagcaaca aatcaaagaa atctatgaag caaagaggaa
    25321 gtacgatagg tcgtgaaaaa actgccctat atcaagtatt aaacaaataa agataattac
    25381 tcatattttt catttgagta ggcttattgc cacaggaaca ttaggatcag aaatggagtt
    25441 gtaacaagac ttctgtcaca actccattcc atactattcg tctttttgct catggtgttc
    25501 ttttaccagt tttttctgta attctttatc ataatttcgg gcagctgacg ttaaaaataa
    25561 aacgattccg cataataaaa tcccgattcc ggaaaacaag aacatttttt ctacccctaa
    25621 acgatcagct aatggtcctg caaataataa tccaattgga cctgccaggt tcatcaaaga
    25681 gttgaagttc cctaagacac gacctaaaac attcgattca taactctgct ggatcattgc
    25741 catcagcagt gtattgaaat atggcgttgc acaacctgct cctgcattca agataagaaa
    25801 gtacaagaac ccttgactat cgtttggaac caatccgctt gcaccgatcg tcaggcccat
    25861 aatgatgtag gctataataa taggtttcat tcggtctttc catgttccta taaaactgat
    25921 cagtgcaccg cctaagagca ttccgactgc gtagactact tccactgctc ccgcctgtcc
    25981 aacggaacca ccaaagtaat ctagcgtcat caatggatac agactgattg ctggcatgaa
    26041 caacagcatc acaaatgcac cattgatcgt tatgtaccat aaccctttat tatccatcaa
    26101 ttgctgcagc ccaaattttg catctttaaa aatagtaagc ggaacttcca atatttcagg
    26161 agaaactttt gggatcttca caaaaatcaa taagccgaca ccaaaaactg cccccaatac
    26221 atctaataaa ataaggtaat tgacaggaac gactgaaaac aaagccgcac ctagagctgg
    26281 cgcaatgatg aaattcgctg attggaccat tcctaactgt ccattcgtcc ttgttatgtg
    26341 agaagatgga acgattgtcg gcataatcga ctggatcgtt ggcatttgga atgtttgtgc
    26401 gaccgaacgc ataaacaaag acacaaaaac tagccaaatc gggaaggatt ctgaaatcgt
    26461 tccgactact gctaaaataa gcgcgaaaat cgctacaata atatccgtga caatcaaaag
    26521 agctttttta tcccagcgat ccactagcgg tcctacaaat gggcttagta aaaccatggg
    26581 aatcattcct agtaaagtag caaaactcaa aattgtcgcc gaaccggttt ctcttgtcaa
    26641 ataccagatg atcgcatatt ggacgaccat actagtgatt cctgacaaaa actgtcccga
    26701 taaaaagaac aaataatttc tcttccaatt cgttaaaacg accgactgtt cattttccat
    26761 aaacatccct cttttctttt tcattttgta tagcgtttgc acaacaatca ttatacggga
    26821 ttcttttttc aaaaaatacc tttttcccta aataacaatc gtttcaattt aaatttcttt
    26881 acttagaaac aataaatcag caaaatatta aaaataacaa catgtgttaa atttaaaaat
    26941 aaaaaagaca actaatttgc gtcgtcctta caaagttagt catctaacaa taggccgttt
    27001 caaaactagt tgtcttttta tatccacaga tcattcgact ttttcgaata acccacggct
    27061 aatcatccca tccatcagaa aataaaattt atcttggctc attttctgtt ttggatcttt
    27121 gaaaatattg actgctttca atccatttgc tgtagtgatc gacattttca atgtttgaat
    27181 atcttttgat acagtgattt ttaatttgaa tccttctttg ctttgcggcg tggcatctaa
    27241 tggtcggatc aattgataat tgcctccgtt tgtttctgta aatccattat cgcgcaatgt
    27301 atatcttttt gcatcaggat gcaaacgata gctaattggt gcgcccagta ccgttgctgt
    27361 tgtttcaaat gccatgattt tcacctcgat aaaattagtt tctctttatt ataaaagttt
    27421 atcctgattt ttactaggtt tttcagttaa gttccctaaa aaatgaaggc gttctctcag
    27481 acatctgttc atataagaat gacttcacta gttatttttt gacagcacga actaattgat
    27541 caaggaaata ctggatgtcg tcttcggtat ttcccaaacc aaagctgata cggatggatt
    27601 cttttagtat cggtgtatct tctccataca ttgcttctaa tacgtgtgaa ggctcgatat
    27661 ttcctgctgt acaagctgaa ccagtagaaa tagcgacccc attaagatca agcttcatca
    27721 gtagcaaatc atttgcttcg ccaattaagc gaagattcaa cacatgaggg agtttattcg
    27781 ttaaatcacc atttacttga taagggattt cgtttgcttc taatgtatca agaatcaatt
    27841 gctggaatcc tttatatttg ttgttacgtg cttcacgttc ttcaggtgac agcagttcaa
    27901 ctgcttttgc cataccccag atccctgcta aattttctgt acctgcacgc cgcttttctt
    27961 cctgctcccc gcctaaaagc aatgcaggga tatttactcc gtctcgttta tataagaaac
    28021 cgacgccttt tggcccattg attttatgag cagagatact taataaatcg attcctaatt
    28081 cttctggatg gatcgtttgg tttccgtacg cttgtaccgc atctgtatgg aaataagctg
    28141 gatgatccgc taaaagttca ccgatttctt tgattggcat caaatttccg atttcattgt
    28201 tcccgtacat cacagagacc aagatcgtat cttctcgtaa cgcttttttg acctcttcga
    28261 tcgacagatt ccctttttca tctacaggca gatatgtaac gtcaaacccc tttgtctcta
    28321 aatatttcat ggtattaaga acagcaggat gttcgatagc tgtagtgatt agatgtctgc
    28381 cttctttttg acgcgagaac gctgtttcta agatagctgt attatcccct tctgttcccc
    28441 cactgttaaa gatgatctcg tgaggttttg cttgcagact gtctgcaatg atttgtcttg
    28501 ctgtttccaa tttttcatgc gcgtggcgac caaatccatg tatgcttgaa ggatttccaa
    28561 acgtgtcttg catgattgcc gtcatcgctt caattacttg tggatgcatg ggggtagttg
    28621 ccgcatgatc cagataaata gttttcactt cattcatccc ttccaaatta ttgctaggca
    28681 cattctagca taaaatagcg aacaaaccaa agaagagctc atttttgtct agaggacgtt
    28741 tcatgggcat agaaaaaagg agctgtgaca aaagtcttgt cgcagctcct tgaagctgct
    28801 cacttctgtc acaacttctt tccctctttt ttttgtttat tcgaattctt tttcttccag
    28861 acggaataac ggactcatcg gtgtattttc atggatgcgt ttgaccgctt cacccattaa
    28921 ttctgaacat gtaacgattg ttaagttttc tggatgacga ttttcttctg tgaaaacaga
    28981 atcagtgata caaatatctt tgattggtgc attgtctaaa atacttttcg catgatcgga
    29041 caataatcca tgtgacgcac aggcatatac ttcttttgcg ccgttttctt ttaatacatt
    29101 tgctgctcgt gcaagcgttg ctcctgtgtt caagatatca tctaccatga tacatgtctt
    29161 tccttgaaca tcaccgatca cataaccacc ctcagttgaa gcatcatctg catgatctac
    29221 gatggctaat gtgctgttca aatattctga aagactacgt gcacgctgaa caccgctgtt
    29281 ttttggcgaa acaactacga tgtcatctcc cgtcagacct aattgacggt aataatgagc
    29341 aaacaacggc atcgtaaata aattatctac aggaatatca aagaatcctt gtacttgaac
    29401 cgtgtgcaga tctaaagtca gtactcgagt tgcccctgct tcttcgatca agttagcgat
    29461 caatttcgca gtgatcggtt catgaggttt cgccgtgcgg tcttgcctag catacccata
    29521 gtaaggcaat acgacattga tcgttttcgc acttgctcgc ttcattgcat cgatcatgat
    29581 cagtagttcc atatagtaat cattgacagg tgcattcgtt gattgaacga tatacacatg
    29641 atcccctcga atactttctt cgatattgat ggaaatctcg ccatcactaa attgcttcac
    29701 gacgctttta cctaattctg ttccgaacac tttcgcgatt ttttcagcta atggacggtt
    29761 gccattcaaa ctaaaaatct tcaacgtgtc atcctgatac ttattactca tgtagtcctc
    29821 cccaaaactt ctctattctt cgatagttta acatattttt ccaagatttt ctgttaattt
    29881 cagcaaattc ttaaggaagt gaaactgttc cgttactcca actggcagga atgactttat
    29941 gataatcgcc ccagttgtcg tgtactttgt aataacgttc tcctgtttca gtttcaaaat
    30001 aagcgtacgc tgtcacccaa tgattgccat atgtactgcc aagtactttc aaaataccaa
    30061 tcatcacagg tttgccttca cgtatacgtt ttgtagctcg ctgccatgaa cctagaagag
    30121 ttgctcgtgc acgctcatga ttgccattct tctttaaaaa actagaaatc cctgtactaa
    30181 cctgaaaagg aatcgtagga agtcctagtg gttggatctg gctacgcaat gccttcgtca
    30241 aaaccaacga atcagccgta tttttcttgc gaatctcatt tggaagcatc caccccttac
    30301 gatagtcttg ataataggca aggagaactg ctgccgcgta agtaccacaa agatagcctg
    30361 agggggtagc ccatttctta tacctcaaaa aacgttcttc tggcaatccc acccagcaat
    30421 ttgcgagttc ctttcctgac cttttttctt cgatcaaaac gggaatatct tcttttctgt
    30481 tgatccatct agataactcg attggctctt cattgatcag cttccatttt ttacaagaaa
    30541 gaccctcttg ataagtatat tttgctggag aatattctac cggatgtcct gattgatcga
    30601 taatcacata actttgatct tcaaaaacca gagctaaaaa aagcaattta ctttttcttg
    30661 actgcagctg ctgagtgctg gctaattttt taattttttt atctactttg aaatataaag
    30721 gtttatccac tacttgattc agttgggatc gcctcctttt tttcattata agtgaaggat
    30781 tgaaaaaaac aaatcagttt gattgttcga attttcaatt ttttatgttc tatttgttaa
    30841 ttccttcatt ttgtaagata atgggcacac gaaacaaaaa aggagcgatc gatgaatgaa
    30901 caaagaacga ttgaaacaag atttctatga agcagtcaat gaagaatggc aaaaaacagc
    30961 aaaaatccct gcagataaac cagctacagg cggtttccaa gatttagttg acgggatcga
    31021 ccaacttttg atgggagaaa cagacgatct gcttgcccat ccagaaaaag tgtcttcaga
    31081 aaaaatgaaa catttccttg catattatca actggcaaac gattatgacc gaagaaatga
    31141 gttgcatgct caaccgcttc aacctataat cgaaaaagtt gaatcattgc agtctttcga
    31201 cgaattgaat aagcaatttc cagaatggct gttggataca ttaccattgc catttaatct
    31261 ggatgtagat gcagatatga agaatgcgca aacgaacgcc ttctttgctt atccgccttc
    31321 tttattcctt ccagataaga cgtattatgc atcagaccat cccaacggtg cacaactaat
    31381 aggcgttttc tttgatatgg ctgttcagtt attagagctt gccggcaaag aaaaaagtca
    31441 ggcagaagca atcacggaac aagcagtgca atttgataaa ttgattgctc ctcatgtaaa
    31501 aagtgcagaa gaaaacgcag attacagcaa aatgtataat ccgcaatctt ttgatacatt
    31561 tattaaatac acagataaac tggacttgaa aaaacttgtc acgggtttga ttgggacaac
    31621 tccagataaa gtgatcgtaa ctgatccagt gtacttcgat catttgaatg acatcctgac
    31681 agaagctcat tttccgttat tcaaaagctg gatgatcatt aaaacagtac gttctcttag
    31741 tggttatcta tcagaagaat tccgccaagt cagcggaatc tattctcgcg tattgtctgg
    31801 aacagacgaa gcaatgcctc agaaaaaagc agcgtattac cttgcctctg gacaattcga
    31861 tcaagtagtt ggcgattact acggaaaaaa atattttggc gaagctgcta aaaaagacgt
    31921 agaacaaatg gtgaaaaaaa tgatcgccgt ttataaaaaa cgtctagaag aaaatgactg
    31981 gcttggggat gcaacaaaag aaaaagccgt cataaaatta aataacttag gtatccaagt
    32041 aggctacccc gataagatcc cagcattatt cgaccagttc aaaacagtac ctgcagatca
    32101 gggtggtact ttgctttcaa atactcttgt tttcagcaaa ctcacattaa aagatcgttt
    32161 cagcaaatgg aacaaaccag tggatcgttc agaatgggaa atgagtgctg acacggtcaa
    32221 tgcttattat catccatttc ggaatgtgat cgtctttccg gcagcgatcc ttcaagcacc
    32281 attttacagt ctagaacaat caagctctgc taattatggt ggaatcggag ctgttatcgc
    32341 tcatgagatt tcccatgcat ttgataataa cggcgcttta tttgacgaat atggcaactt
    32401 gaacaactgg tggacagaag aagatcttac acaatttcaa aacaaagcac aagcaatgat
    32461 cgaagaattc gatggtctgc cttttgctga cggaaaagta aacggaaaat taaccgtttc
    32521 ggaaaatatt gctgatgcag gcggtctaag ctgtgcattg gaagcagcaa aaacggaatc
    32581 agatctttct atcgaggaat tctttgtcaa ttgggcaacg atttggcgta caaaagcaaa
    32641 aaaagaatac caacaacttt tactgcaaat cgatgtccat gcccctgcta aactccgagc
    32701 aaacgtgcaa ccaaaaaacc ttgacgaatt ctatgaaaca tttggtatca cggaacaaga
    32761 cgctatgtat ctagcgccag aaaaaagagt gcgaatctgg taagaggttg tgccagaagt
    32821 ggtcagcttc aagaaataag aaggaatttg ggaaaatcgc ttctcaaatt tttgtgacat
    32881 ttcggcttat ttttcgaaga agttacttct ggaataccat gtattagagg ttgtgaaaaa
    32941 gctgcttagt ttcaagtagt aagaaaaatt ttgtgaaaat ggctttccac atttttgcat
    33001 aaatttgact tactaccgag aaactggctt ttgaacaccg tttatcgaga ggttgtgaaa
    33061 tcagcgtcct gacctgagta ttagagaaaa aaacggaaaa atagttcctc atattttgcc
    33121 gtttgttgag ctaataccga gggtcagctg attgaacacc gtttagtgga gagattgtga
    33181 aaaagctgtc ctgcatcaag taataagaac agccaatcaa aagcagcaag gagaacctca
    33241 tctataaaaa gatagaagga agtgagacat ctattggtct catttccttc tatttttact
    33301 ttcctcagtc aattgtttta catcataaaa ggagaaattc cacttatttt tttcgctgtt
    33361 tcatgacata aacaactaca ccgattaaca aaattcctcc agctaatgct agcaacgggt
    33421 tattaaattc tcccgttttt gggagtcctt gagtgccatt tttttcactt tcttttgctg
    33481 tcctatccgg atgagaaggt tttccatttg gttttccatt tggtgattca tttcctggat
    33541 tttctctttc tggtttgtca tttcccgggg gcacatcggc agtttctcgc acagtgatcg
    33601 ctttttgctg ggtaacagat tctgtatgag cagaccattt ttccccatca aatatttccg
    33661 aacgataagt gacttctagc gtatattctc cttttgaagg tgctgaaaaa atagcggtat
    33721 gattagaaaa ttgagcactt gactgtgttt caacgatttg gatcttttct gggaaataac
    33781 gcatatcttc aaagacaggc gttccttgat ttggtgtgaa agttgacaca aaaactgtaa
    33841 aaggcttcag ttcaatgata tttccttctg cattctccgc cacaccattt gcttcttgta
    33901 taataatcgg attattttgt tcatttggtt ttgtctgatt tggttcttgt acgattgcat
    33961 actctggata ttccgaagac ggtgaggttt ctccgtcaaa aatagcacct acagataatg
    34021 gaagaccatc cactctttcc ttttctgttt gacgattccc cggtttaatc tgcatcagtc
    34081 catgaacatg gatacttcca ttttcatagc gcgtaacagg ctgctgacct tctttcgaac
    34141 atgtatttag agactcgatc caatcttttg atatggtatg tccaagagta ttttctgatt
    34201 gtttctctcg ttcattccaa tagtagttca acgagtggta gatttgatct tcgttttgat
    34261 tcaatgggcg gatctgctct ctcatctcaa gattctctgt tcggaaagat aagataccag
    34321 aagcatggta gtctgtgttt cctgctgaag aggtataaag agccacatta tatgaaccgt
    34381 tattaaaact tgtactgcta ttgacgataa tatctgttcc gctattggaa tcgattcctt
    34441 tcgcaagatt ttcgaaagac aaactattga tcaattcatg agggcccgtt aaagaagaac
    34501 cgcccatttt gaatccatta ccgttacctt ctccctcaat tcctggtacc cagccgtttc
    34561 gataagcaac tgagtttttg atgattactt ttccgatcga acctgtttca tttttagcaa
    34621 aaaggtccca accgtcatct gcattatgat acgcgataca accgtcaaat acatttcctt
    34681 ctcctattgt cagtttggcc gcaaatccat cggcatcttc aaatcctgga tcggcatttt
    34741 caaaagatgt acagttcttg actaagttat gcgcgggcca tgcttcgaaa ggatcatttg
    34801 agctaccgct gatttggatt cctgtatttc cattccgata agcatgaatc tcttcgatca
    34861 aattatgatt tccagaaatc tgtaatcctt tttgcatagc tgcactattt gtaatgtcaa
    34921 accctcgtaa accccagtag tgactgaaca gtgtcatccc atttccagtt cctttaaaat
    34981 caagtacagg acgcttgttt tctggatttt tctctgcaat caactgaatc gggttttctc
    35041 ttgtcccgtt aacgcctttt ggaatcgtca atcctctttc gaaggaataa gttccaggcg
    35101 ccatgacgat tgtctgccca gcatatgcgt atctcaatgc ttgtgtcaga gataatggat
    35161 tttgtctgct tccgtttcct gcatctgacc cttctggtgt tacataaact gtcgaatatt
    35221 taggtttacg gtagtccact gtatgaagaa tctcttttgt ttcataacta gtcatctcta
    35281 cgtattcttc tggcggatag tttttatctg gcgtaaaact gaaagtaaat tcgttcgttc
    35341 cttccatcag ttttgtctga taatcaaatt cccgattcgc agtgatagcc aagttttttg
    35401 cgttcttaag cacctctcct gttgctttat ttttaattgt caataatccg tcagcatttg
    35461 ctctaaagga catagtatga tcttggtttc ctgaatgatt actagaggtc acagtgtaaa
    35521 tcggatcaat caagcgagta ggtctttctt gcccaggagg atctgtcgca ggatctgagt
    35581 aagcaacttc gattccttct accttgatcg tcatattcct tgctgcagca aatcctgcat
    35641 aaataaccga ttcatctgaa gcgtataatt tttcccagtc atacatgatg tcagaagcca
    35701 tttcttctcc tgtttcagga tcgtaataat atgcctctaa accagtattc gtttttttca
    35761 tctctacgtc cagtttagta atcgagttcg tggccggaaa cagattccca tgaccgtttc
    35821 cgaatatatt ataagaacct gtttcttttt ccaagaaccc tgctgaagtc tctaaaggtg
    35881 ttgtttccac tgagacactc ccaggagctg gcgcagcttg cggatcttca gatgatattc
    35941 ctgtgattgc ccgtgtcccc aatccaagtc gcatcgtata tttgctgccg ctcgtgttga
    36001 ccacttcttg tctatccgag tcccagacat attcgatccg actgcctagt atggcaaatg
    36061 aatttgaata aaatgcctgc ccaaacaaat gattttttgg tactgcgtct cttaccatta
    36121 aagcaaatcc ttcttgggca ttcgtatagg tccaagattc tatttcgatc gtcgcccgca
    36181 tcctaaagtt gatgtctttg gggattgctt gataataata ggtcattcca tctgatccgc
    36241 ttgactggaa ttttccgccg ttattcgtgg aagagagccg cacgccgtct tctaatggtt
    36301 caatggcata cctactagca cttgtgcttt ctccgaaaac aacccctttc cactcttcat
    36361 ttgcttcttc agattgcttt tttgtctttt cattttctga ttctttcatc ataggatcat
    36421 ttccttcttc cgtatccata tcttcactag ttcttggtat ttcctccatt gttgacatcc
    36481 cttcaatgtt cacgtgtgca ttttcttcgt tcacagactg ttgttcgtta gcagcaactt
    36541 caacgacaga aattaaaacc ggggtactga gcataaggag attcatcatt agcgcactgt
    36601 attttatacg tttttttaac aagtgtattc ctcccgtaac aaattagaaa gcgtttactt
    36661 aaagtattac ctaatttatt tttactgtca ataaaaaaca aaattataat aagtgtattt
    36721 tataaaaaga aaaaatataa cttaagttgt tgataataaa gagatttatt aacggaaaaa
    36781 gaataagttt ttttaaaata acgtataaaa aagagcataa aacaaagtcg tttgttttat
    36841 gctcttcttt tattattttg tgctttttat tttatcaaat cactttgttt ttttataaaa
    36901 tttctgcgcc tagtgtggac tcaaaatgtc tcaatgccca ttcatgtcca acgggatcga
    36961 aacttgccac ggaatctttg aaaatatgga gtttgtatcc tagattatac gcatcgactg
    37021 ctgtatgcaa cacacagata tctgtacata cgccggtcaa ataaatatct gtgatctggc
    37081 gttctcgcaa acggatgtct agatctgttc cactaaaagc ggaataatgc cgtttgtcta
    37141 tccaataaac attttcctct tgctcatagt cttggtataa actttttaaa gagccgtaca
    37201 attcccgtcc acccgttcct atcacattat gcggaggaaa taagcggttc tccggatgaa
    37261 aggaatcttt tggatcatgc gcatcaatgg caaaaacgac aaaatccttt tgatcaataa
    37321 acttctttgt atgagcagtc agcttttttt caattacttg tcctgctgtc ccagtagtca
    37381 gctttccatc ctctgcaaca aaatcatatg tgtagtcaat cgagatcaat gcgttcatct
    37441 tagtcctcct tatacgagat gtttgacaaa ttcgatcacc atttctgctg atcgtttgcc
    37501 tgcgtcttcg ataaattcgt caaagctttg tgtcgccgag tgatctgctg tgtcgctcat
    37561 tgcacgtacg atcaaaaatg ggatattgaa ctgacgagct gtttgtccaa cagcggctcc
    37621 ttccatttcg caagctaatg cttcagggaa attcgttaag atttctttga ttttatctgg
    37681 cgagtcgaca aatgtatcac ctgtaacgat caatccttct tttgcgttca aattcgttgc
    37741 ttttgctgct ttaaccattt cactgcgcaa atatgtgctt gcttcataat atagaggcat
    37801 tcctggtaat tgtcctgggt tgtagccaaa tcctgttgca tctgcatcaa aataagctac
    37861 tttgtctgat ataacgatgt cacctacttg taagccttca ccgattccgc cagctgaacc
    37921 tgtattgatc accatgttca cgccgtattg ttggatcaac agacttgtgg taatagatgc
    37981 taagactttt cctataccgg aacgtacgac gatcacttcg tggttaccta atgaacctga
    38041 aataaataaa gcgcctgcgc gttcccatga taatggttcg cttaggttct ctctcaaaat
    38101 ttttacttct tcttccattg cgccgataat accgattttc atctttttaa ttccttcttt
    38161 ctatataaat gcgattgcta aaaaaaccac acataacatt aggataacaa taataagaga
    38221 tttcatcaaa aaagagttcc atttggtcgt cttttcccgt tcgctgatcc ttgttttcgt
    38281 gattggttta ttctttttgc tttctttacg ataaaagctg gcaatctttt tttcttcttg
    38341 ctgataagct gtttctgctt ttcgctgttt ttttaatgac tcgcttgctt gtgcttgttg
    38401 tcgcttgcga agttcgcttc gcgtaataag cggtcctttg gccataagcc gatccctcta
    38461 ctttcctttg gtcaatagtt cccagtattg aatcgcataa atcgtctttg catcacaaat
    38521 caactgatct ttcatcgctt gttgcgcctc ttcaagagtt agatgataca actccagtac
    38581 ttcgtcttca tcttgtgcta aaggattctc gaccttctct accccttgtg catgataaat
    38641 atgaaggact tcatttgcaa aacctggtga aagatacatc gaagtaagat ggctcagcga
    38701 cttcgcacga tagccagttt cttcttctaa ttctctagct gctgtcattt cgggattttg
    38761 tccttctcct ggatcgattt ttccagctgg aatctccaaa atcacttttt ctaaaggttt
    38821 tcgaaattgt ttgacaagaa gcagacgatc ttgttcgtca aaagcaatga tcccgacacc
    38881 gccaggatga aataccagtt ctctcttcga agttcctcca tctggcaaac gaacttcgtc
    38941 tacagcaaca tcaataattt ttccgctata gatttctttg cgactgattg ttttttcttc
    39001 aaattgctca ttgttcagca tatcttctcc tgctttcttt gtaatcataa ctgctttttt
    39061 ttcatttttc aatttttctc aaaaactcct tattagttta ccatagataa accttagatt
    39121 ttctctaaat atagaaaatc cttctttagt ccgatactct ttctagtagt ccgtatgcta
    39181 aaataagtat gtaatcgaat aacgaaaaga attcaatact caacgataaa tgacatggag
    39241 ggtttattat gataaaacga aattggccgt ggcttctagc attggtcttg ctatttctct
    39301 ttgtccgaaa caatagtttt tcttttgttc taggactttt attgataggt gtagttttag
    39361 ttttgtgggg actctttggt tcgcgcagga aaaagggaaa acaagaagaa attcctgcac
    39421 tgactgacga acttgaaact cactatgaaa aaagcggtat gacagcgaat gaaatttcat
    39481 tttttcgaca aacaatgaat caaacaaaaa atgagatcaa tcaattgcaa atgaatatgc
    39541 agcagacagc caaacttaaa gcaatcgatc tccgccatga tccagtcaaa gcagcgaaag
    39601 ctttattcaa agaattggtg aaagaaccaa accgactgca tgaagcaagt cagtttcttt
    39661 atacgcatct gccgaatcta gttgatttga caaataagta taatgagatc aatgaccatg
    39721 agatcaaaaa caaacagacc tatgaaaaac tagaagaaag cgcgcagatc atcgaccagc
    39781 tgtcagcttt aatcgcacaa gattatcaaa aattcgttgc tgaggatcta gatgatatcg
    39841 acgtagagat atctgttgcg aaacagagct taaagcgtga taataaatat gaaccagaac
    39901 aaaaggatta actcttttgt tcataaaaga agactcggaa cattcagatg atgtctggct
    39961 gtttcgagta ctttttctaa agtagagaca ttcatgtaag aatcgagaac agattcaaca
    40021 aggaggaatt ttttatggat cataaaccga ctgaaacaaa agatgttaca ccagttaacg
    40081 atacacttga agatttattg aacaacccgt tttcaactcc aacagatacg ctgaccactt
    40141 cacaacaagc ggagattgat cagctccaag agcaacagac agctgctcgt ttaattgaca
    40201 aactaccggc ggaacgccaa gaacaagcta aacagctagc agcaaaaatc gatgctaatg
    40261 atgcacagtc tgtcatcagc tacggatcgg ctgcccaagc aaaattaagt gaattctcac
    40321 aatcgatgtt gaatcatgtg caagcacaag atattggtcc tgtaggagat tccttaactg
    40381 aactgatgta tcgtctccaa gaagccaatc ctgacgaact gcgtgccgga gaagggaaca
    40441 tcttccagcg tgtcttcggg aaggtcaaac aatcgatcta tgaagtgaca gcaaaatatc
    40501 aaaagattgg tgcacaaatt gacaagattt cagtgaaatt agataaagaa aaagacggtc
    40561 tgctaaaaga taatctgatg ttagaacagc tttaccagaa aaacaaagac tactttgatg
    40621 cactgaatat ttatatcgct gctggagaat tgaaaatgga agaacttcaa acaacgatca
    40681 ttccagaagc gatgaaaaga gcagaagaaa ctggcgatca gatggatgtt cagattgcca
    40741 atgattacac gcaattccta gatcgtctgg ataaacgtac gcatgatctt cgcttagcta
    40801 gacagatcac gatccagcaa gcaccacaaa tccgtttgat ccaaaacaca aatcaggcct
    40861 tggctgaaaa gatccaagca tctatcgcta cagccattcc gctgtggaaa aaccaagtcg
    40921 tgatcgcatt gaccttgctt cgtcaaaaag atgcagtaac tgctcaacgc caagtctctg
    40981 aaacaacaaa cgacttattg aagaaaaatt cagaaatgct gaaaatctca gccatcgaaa
    41041 cagcgaaaga aaatgaacgt ggaatcgtgg atatcgagac ccttcaaacc actcaaaatg
    41101 atttgatcga aacaatccaa gagacattgc gtatccaaaa agaaggaaaa gaaaaacgtc
    41161 gtcatgcaga agtagagctt ggacacatgg aagaagatct gaaacaaaaa ctgttggatt
    41221 taacccaata gatcaccttt cgcttgttac taaaacaaac gcccaacaac agtttattac
    41281 aactgttgat gggcgttttt cttatctttc ttctaacttc tccattggag tctatttctc
    41341 attcatcttg ctgtgtccat agccatagcc aaaataaatg atcagtccaa taaccattac
    41401 gataccgaac acgatccatg tcacagtttg cagacgaagc atcaatacaa tacaagtcaa
    41461 gatggagacg attggcaata gcggaacgaa tggcactttg aattctccag cttttggttt
    41521 gccaaacatt tttctcaact tcagtaagcc tagactaaca agcatcaaat aggcgagcgc
    41581 catgatattc gttagttccg ctaatacatt caatgggaaa aatccggcaa agaatacagc
    41641 tgccacacca gcggcataag tcgctttttt cggtgtacga tgcttttgat cgatttctgt
    41701 cataaactta ggaagtaagc catccttgct gacagcaaac agtaaacgag caagtgaata
    41761 catcatcgag atcgttaccg tcagtagcgt taaaattgcc cctacagcga tcaccgcgcc
    41821 cactgttcca tgtcctacat acctcattgc aaaagccact gggtcattga ctcctagttc
    41881 agtatacgga acgattcctg tcaagatcag cgtcacgatg atgtaaagga cagtagcaat
    41941 cagtatcgaa ccaatgattc ctcttggcac atctttttgc gggtttttga cttcctcggc
    42001 tgccattgca acggcatcaa atcccaagaa agcaaaaaac acaagagctg caccatctag
    42061 cacaccggaa aaaccaaaag gcatgaatgg ctgccagtta tcaggtttaa cgaaaaatat
    42121 tcctacaatg ataaacaacg cgatgatacc aaatttgaca tataccatgg cattattcaa
    42181 acgtaatgct ttcttggctt caagcgacac gatgtaagtg acgaatatca ctacgagcac
    42241 cgcaatcaag tcaatgtatg taccattttc cggattgtac ccgccagtta atgcttgtgg
    42301 aagttcggcc cctaaacttt tcaaaaaacc ttgcatatag ccagaccatc cggaagcaac
    42361 agaggaaacc gctagtaaaa attccccgat caacaaccac cctgtcagcc aggcagcaaa
    42421 ttcaccaaat acaacataca gataggcata tggcccacca atcactggca ctcgcgaagc
    42481 aaattctgcg aaacttagtc cagacaaaat gacaacgatt gcagctaaga caaatgaaag
    42541 tgacagtgct ggaccagcat tttgattggc cgcaacccct gtcaccacaa atattcccgt
    42601 accgatgatc gcaccaattc caagcatgat caaatcagac gtttttagtt cttttttcat
    42661 ctcactcgta tgattgagat tgatctcttt cttacgaaac aaatccattg aagttcctcc
    42721 ccattttagg ttggaaaaca gcgattaaac tgttttcata taccctaaaa ggataccacc
    42781 taaaatgact aaaaggcaac caacaataac ataaatgagc tcttttttcg tttttctttc
    42841 gccaaggatg aaaatcccac ctaaagtaga gataatgatc cccatttgtg aaagtgagaa
    42901 gccaacagct aaaccaagtg atttgactgt tagaagcatg cagatgtttc ctaagcccca
    42961 taataatcca cagatcatgt ttttccacac aaactgatcg actttaactt tacggaaagc
    43021 aaagaagctt gcgcctaaga tcattccgat actttgaggt aagataattg acatcgcatc
    43081 caaattcgcc cagttgacga tgatggtata tacaccataa ccaatcgtag agaagatcaa
    43141 tgctctaaaa cccttaccaa aatcaagcat tttattatct gtatctattt ttccttcgtc
    43201 atcttgtcgg gcagtcaaat acgcaccgct tacaagaaga gctaaagcaa taataccgta
    43261 tacataatct ttcgtttgtg tccattcatg gaagaaaacg gctcccgcaa tcgtattcaa
    43321 aattaattga aaaccagtag acaatggtag ccctacagaa acacccatgt acttcattcc
    43381 atggaactgt ccattttgtc caacactcca agctaagccg gataaaaatc cgatcaagaa
    43441 aatccaaggg gtgattacag gactaacaac gaaaaagaca actaaagaaa acagaaatgc
    43501 accgatcgtc attcctagtg tttgttgatt ggcatcgcca ccaattttac cacttactaa
    43561 accaatacta ccccatgcca acatagggac taatgctatt aaaatttcca taaccaatct
    43621 ccttttattt cacatgataa gaaacttatc agcgaaaacg ttaacaacac aagcactttt
    43681 tttcgtttct aacgattttc taacgttttt cattataaaa atttaagatt gggaaaaata
    43741 aagtcattgt tgtccctttt ccttcagttg attcagccgt caaatggata cctaattttt
    43801 cggccagatt ttttgctaaa taaagtccta atcctgttga atgtgttttg ctaagtcgac
    43861 catttctccc agtaaatccc ttatcaaaga tccgtttcaa gtcttccgct gggataccga
    43921 tccctgaatc tttaactgaa aggctgactc cttgcgcttc cttttctatg ctcacaatga
    43981 tgtttccgtg atccggcgta tatttgatgg cattactaag caattggttg aagataaaag
    44041 cgatccattt agcatcggtc aaaacagtat gatcctcacc aacgatctcg tagcgaatat
    44101 ttttttggat aaaataattt gcctgactgc gtatcacagg ctgaatgatt ccttttagtc
    44161 catattcttg gatgaggtag tcccgcgaga aactgtcgag tcttgcataa tacaaaactt
    44221 gttctacgta ttcatcgatt tttgataatt cattttctag taatgtatac ttttgatcgt
    44281 caatatcgaa ctcgatcgaa cgaactagca atttagaagc ggaaagtggc actttgattt
    44341 catggaccca tgagtcaata taatcttttt ggtcttgttg attactgatt gctgattgca
    44401 ttacttcttg gtgttcacgg atcagctgat tgatatattc ttctaccagt ttttcttctt
    44461 ctgtcctccc accactcaaa taattttgca aaggggaagt tttttgtatg tcggctaatt
    44521 ttccccacca tcttctcttg ctcaagtaac cacccagcag ataaaaaatc agaaagacgc
    44581 cctcaatcaa agctaaataa gcaattgtgc tcaaatcaac tttgatgttt ggcgccagcc
    44641 acatcacaaa gatcgtcaat gcaataaaaa acagccatcc caagatcaat gtccactgat
    44701 ctttcaaata tttaaaaaaa ttcatcttaa ccgctcatcc tttcagggaa cgatatatcc
    44761 ctgtcctact tttgtttcga tatatccttg gatacctgcc tgttcgattt ttcggcgtaa
    44821 ccgattgatg ttgactgtca atgtattgtc atctacaaat cgttcgtcat cccacagtgc
    44881 tcgcagcaat ttttcccgac ttaagatctt tccattgtgc ttcatcaaaa taaataatag
    44941 acgatattca tttttgctca aatcaatgat ctctccgttg atttccatac ttccgttgtc
    45001 aacattcaac gtaatgccat tgtggctcat catttcacta gataattctg tgtagttgta
    45061 agaacggcga agtaatgcat tgatttttgc aatcagtaca tcgatttgga aatgttttgt
    45121 cacaaaatca tctgccccca tgttcatagc catgatcata tccatattcg tattcctgct
    45181 ggagataaaa atgatcggta ctttcgatac ttcacgtatt ttttgacacc aataatagcc
    45241 atccaaaacg ggaagattaa tatctagtaa tacaagctgt ggttcttctc tttcaaagtc
    45301 tgagaacact tgattgaaat cggtcgttcc aaaggtttca aattgccatt tctcaagttc
    45361 ctccatgatc aattgtcgaa tgatctcttc gtcttcgact accatgattt ttgccataaa
    45421 aaatccctcc atctttcttc ttgctactac aatatcaaag aagcccttgt gaaacaagtt
    45481 ggcttacctg gaaaatgtca ttttagcaaa cgttaaaaaa aactggaaat atgcgattta
    45541 atcgcgtttg tctcttccaa gcagcttaaa tttattatgt tattcttaat aattggtcta
    45601 ttatctgtta tttttctttc gttgtttttg tcttttaaat tttcgataac accaataacc
    45661 gaaaagcgtt agcactagca atatacctag aaggagtata agtaatcgat aaagatggta
    45721 tttttttgtc tgttctatct ttgaagagac ttcttctgta aagggaactc gtcttcctgt
    45781 cactagtaat cggtgagtgt tcacggtgta aggtgtacaa gtgataagtg tgactagatc
    45841 ctgcttttct ctaattgcta atgtatttgt ttttgttgga aggacaacaa ttttctcaac
    45901 gacttcataa gcgagcatcc gaccatacac ttcaagatag aatcggtcat cttgctccat
    45961 ttcttcaaga tccgtaaaga gttttttctc agcaataccg ctatgggcgg taatcacgga
    46021 atgtgtactc tctcctccag ttggaaaaga ggtgccttgc aggactgtcg ctcctctatc
    46081 taacaaaaga tcattcgttt catcaaataa aggcaagcta acattgattt tcggaatata
    46141 gatggctccg atcatatgtt gttcgtaata ttcttttcct ggattttgga catttctaac
    46201 cgcttgctca aaaggatctt tgacttgtcc cattcctggg attactgatg tatgagcaag
    46261 cgtctgattt ttcttttcat gcactgctaa ttgttgctca tgtttttctt ctttatcgcg
    46321 ttcaagctgc ttttgataat tctcgatcct tctttgatcc aaataattgc tgagagcatc
    46381 tgctaaaaat ggatatgtaa aaactgcagc tccggcaaga aacatcactg ccataaataa
    46441 ttgtaataaa agactgattt gggtttgagg tctattacct attttctttt tcattttctt
    46501 caccttctta tttaaaaaaa ctgcagcaac ctttataaaa ccgattgctg cagcttattt
    46561 ttgttgctta tacttcagac ttcattttag atttacggta ccagctgtac gctccaatca
    46621 tcaaacttat tccgattagt aagaatgcca agagcccgtt cccaccagta gcaggaagtg
    46681 acccgcgttt catattcggt actctttctg gccctggatt ttctactcct acgatctgaa
    46741 tttcttcatt atagcttcca taagagatga taaattcagt aaaggctgcc tcacctgttg
    46801 gaagtacata accttctggc gccatggtct ctttcatttg ataggttcca taatctaacc
    46861 cttgaacctc aaagtatcca tttccatctg cgacaaattc tgttgcttgt ccgcttgttg
    46921 cccactcaat tctatctgct cctgattcat aaacagctaa aggcgactcc cctttataaa
    46981 atattgcgta ttcagaacgg tcttcattcc acaattcgaa tcttgcatct ttaagcaatt
    47041 cactgcttga tgcatcatat ttttcaaact ttcttccacc tgttgtgact ttctctggcg
    47101 gctctactcc ttcttcataa tcaaattcat catttcgtcc gatttcaata accgctgtgt
    47161 tgttatggaa atcatccgct tctagttctg tggaaacctt caaattatac gtgatcgtta
    47221 aatctcctcc acgtgcatct gctaatctac ctaaagtatc tactttggct actccatttt
    47281 cttctgtcaa aatcgtcacg acaaacccgt tgcttactac ttctactata taatcttgtc
    47341 cttttgttaa aatcgtctcg ccggctcgca cttctatttc ctgatcataa taagttagac
    47401 caactgtagg cgtatctgtg attttgtaat ttttgataac agcgcttccg ttttcaagga
    47461 cagaatcgat gaaataagga ataggtgctg tgatcgtgta agaagccgtt tttcctcttt
    47521 ctagatcaat ataagaaatc gtttcttgtt ctccagcttc attaataatc gttacttgtc
    47581 taaggtcgct ttcctctaca ttcatctgtt tatctgcttc tctgatttcg tttttcggat
    47641 acaaatgcac atctgtattg tatgtgtctt tccatgtaga accatcccac acgccatcca
    47701 ccatatcagg catcatcact ggcatcataa caaccattgg agacgcgatt ctggaaatat
    47761 gagctggcga ataagtttct aagaaaagat agactttatc tctagaagaa ggtgcttctt
    47821 ccgtcacttg gacggtagag aataccgctt ctccagcttc attcgttgtt tgtttgtcaa
    47881 tacttgtcag tcgatatttt aaaaaccaac tttctgtgtg ccgtttttga atccattcaa
    47941 tcgcttcggc agaattaaga ccgtcttctc gttccggtgt taaaggatta tctcgaatca
    48001 aatcgtaata tacttccgtt acgtcaaaca aatcaaaatc gactcctgga atattttctt
    48061 caccaaaatc cgtagaaacc aatccgctat tcggtcgttc ttccggaaca gatgagaaac
    48121 cttttttgtg taatgtaatc gtcacttcac ttggtttttg tgcgacttct tcggctttga
    48181 ctagttttcc gttcccgaaa atccctattc ccgcagtaac gagtaacagt acactcattc
    48241 ccgtgacaat cattttttta ttcatttttt tctccccgtt ctttttttat taataaaaca
    48301 gcacctaaca ataaaagaat tcctagtaaa gaaatcaacg ttcttgcttc attcgtttgc
    48361 gggaatacgg accattttcc tgattgacct ggattgcttg gaccactcgg ctctttcggt
    48421 ttgtccgttg tttcttttac ggtctcgtta taaacacgtg gtgttgcgga ttcataggca
    48481 gagactggaa ctttcccgga ttctaattca gccatctcct gtccgttaac tactacatat
    48541 tgtggttggc cttttgcatc cacccaaaat tcagggatga tgacctcgat tctcttactt
    48601 gcttcatcca tctcgtaacc ttccacacct tttaattctt caaaataata ggtgccagaa
    48661 ggcaagaaac gttgtcctgt cgtaacaagg ccctctttat ccgaaatgaa tttgcttaca
    48721 tttttgtcat tcaaaggatc attgtctgct ggtttgatcc attgattttt caagtcatta
    48781 gcaggagcca tatctaaata atatttcccc ccttctatca tctgatatag agcaaaaaca
    48841 gcaccttcta atggttttcc tttttcagtt gttcctcttt gacgtccata cttgaagaag
    48901 tatggatctc ttagataacc gacattttta ggatagatat gaatctcttg cagttcctcg
    48961 gttgattctg tcgggtgata aattggcaaa atagcagcaa ttgggatagc tgtctgatcg
    49021 atatcaacat ccaatccaac ttctggatca atcgattctt cgaaaatcaa ataaactgca
    49081 tcccgatctt ggtttttctt aggtgctttg atacgtgcaa tcccgtctcc taatccgcca
    49141 accgtatctt tcccagttgt taccgaagtc cctatttgga caagcctttc ttctgtgatt
    49201 agctgacgga tattgtttct gttcgtttca gcgatttgct ggacgaattc tttaggagtc
    49261 atgttttcag cagctttttt ttcatgataa taatcggtca tgtcgtaaat ggcaaatgtc
    49321 gctccattta gtggcaccgt ctgtgaaatg atatctgctg tttcccctgc ttcctcagag
    49381 atagccaagc catcattttc atggtattca aattgatcgt tataatcgat atctcgaatc
    49441 atccgtttat gcaacacgaa ttccacgaca tcttcccctg attcttctgc cgacatcgca
    49501 tgtggaagaa ggactgctgc aagcggtagt aaaacaagta attgaagcat caaacacaac
    49561 agctttttca ttaccttgct ccctcctttt tagattgtct gacaaacaaa ccataggctg
    49621 ctcctgcaag cgccatgaag aatgcagcaa gcaggatata gaataatcgt ccggatcctc
    49681 ctgtagcagg caacggattt tcaggatcgt tcccgacact aagctgtaat ctgattcgat
    49741 ttgtctccaa aagttcatat tctaactctt gctgtagatc aggcgtctct gcttcttcgt
    49801 ttggataata cgaaatctca acttttagtg tacccgcttc ttttcctgga actacccgat
    49861 cattttctat gtcaggttct tctcgataac taatttctaa aataaagtaa cctggaagtt
    49921 ttctatagct gtcaggtgac ttcacttcct tgatccgata gaccccttcc aacaagtctg
    49981 aagcattgaa tagggaagaa tcgtttggat ctggtgccaa gcctccctcg atgatttcat
    50041 actctcctgc actattttgt ttctcaattg aaaattctgc gccttcaaga cgtcggctat
    50101 tcatactgtc aattttcaaa agttccaaat cgattggcgc tagttcatct tctaaggtta
    50161 cttgtagtac accatcgatg atttcatagc cttccggcaa gggagcagtt tcgtcttcga
    50221 tgaccgtatc ttcaatgata aacttacctt cttcattcag tgcaaactgg aacacttgat
    50281 cagatagccg atacccattt ggtgcgacag attccgagac ctcatattca ccaatagaca
    50341 gatgcagagg ttggtcgtaa tttaaatcga catacttttc tactcctacg gcacgagaat
    50401 agaagtatcc gatcccaggc aaacgtttcg attcttctgg ttctaacgga ttaccagtgt
    50461 atgctcgata cagcgggaag gaagaatccc ccactttcct gatatcgaaa cctgcaccat
    50521 ctaatgtatg gccttcatgg tctaattttc taactcggat ctcccgataa tcaaacgtat
    50581 tgtaagcagt gaatgctacc cataaacgat cctcttcatc tgttgtatac gtgagatatt
    50641 gccaattttc ttcacctgtt tgcttgagtt ggatagtccc tatagcatta tcgtaaagtc
    50701 gcaagatcca tgtgtcattt tcatcaggtt ctttgaaacc ttctgggttc tggctctcaa
    50761 tgattttgta ttctgcatag ttggtagttt cttcactatc cttataaaca aatgaatctg
    50821 gctctccgat tggatgaata actttctcac catccacgat tacatatttc ccgtcttcat
    50881 ctactgaata gaacgtgagt ctccctttct cttcctctac ttcgttcaca ccagaaagcc
    50941 ctttcgctac tggatatccg atttccagtc cgttaccatc tgtttcataa agttcaaact
    51001 ctgcgccatt gattggcata ttactgcctt caattagttt attgatattc atgtggattg
    51061 gcttgaattc atttcgcatt tccagtttga catacaactc atcatactct gtgccttcta
    51121 tgttaggctc ttgtacaaca gaaagcttgt gatattctcc ttcataatag gaattcggat
    51181 ctttaccttc cggtccgccg actctcgaac cagatgtata ttcatctaca agctcgtagt
    51241 gacctaacat ctcatcttcg ttggctgcat attttttgat ttggaattga tacgtctcat
    51301 ctactaactg ataacgtggt ggtccagcga tctctctgat ccaaaatatg tcgctgactg
    51361 ctccagtttc atctcctaaa atcggcatct tcgtttcaaa gatcgctatt ccgtccgtgg
    51421 tagttttact tgtttcgatt ggttcggctt ccccactctc tggattttgg tcatataatg
    51481 caaattcgac tccagccaac ggctcgccat tttgaccctt cttgctgact tggaaattac
    51541 ggcctttatg ttcgtaacga atggaagaag atgggaaata catccgtcca gtagtgatat
    51601 cattctcata atcctccagg ttctgaatat aggccatatt gttcactgtg caaaaatttc
    51661 cgtcttgagc tcccgcatca agttttactt ggtacttgat cctgaccatt tccccttcac
    51721 ctaaagaaat cggagaaaat ttataagctt ggttttcccg tccgacatac gttgtcggag
    51781 tcgccactac ttctggtggg gcttgtccat gacgttcttc atcccatatt tctggctctt
    51841 ggtacttcat gccgttttct cctggatcta gatggtaaaa ctgaatatct gccgatctgc
    51901 cagctccaaa tggtgagaca ttaaaaccag tttcatcata aagtgtggct tgctggatcg
    51961 ttctcttgaa ggtagaagag atatcctcca aggctgtaac aatgtcattc ttgttgttcg
    52021 cattgtaata tcgcggtgtt acgccatctt cttctaaatc agcaatattt ttcaatacat
    52081 ttcgtccaat agcatctagt cgttgtctcc cgctaacgtt tccatcgatt cctaaaccaa
    52141 tggagaagat acttggcggg ttctcttgat acttgttttt cagccaatga tgataagcaa
    52201 ctgtgttgat cgcagatgac ttttcttgcg aagtaggact gccattcgta ttgttattag
    52261 aagaaccatc accaacccag tgagtcgctt tattatctcc ttcttttacc tctccataac
    52321 gatagtgtac atttacttca tcttctggac ggttaaagtc agatgcatag gtaactggat
    52381 gagtaaaccc tgcattagaa gtattcccag aaaactcctc aaaatttctg aacaaaacgt
    52441 cattatcttc agcaatctta tcttccatca cagtccagtt gctccaagct ccattagtgc
    52501 tcgtacgata acttgactga atcggtgcat aactgaaggt cggtgtccca tctcccacaa
    52561 cgattaggat tttttctgga tttctatttt ctccgccatt gtctttatac aatgtttcat
    52621 agccattttt aagccctagt gtaagcggag ttcctccgat tggtgtacga tttaatgctg
    52681 tattctcact tcccgtcaaa cgattgatat catttgtcaa tggaaagatg tccgaactga
    52741 tttgctcatg gttattgata gctgtactat tatggtaaaa attcaccata ccgattcgaa
    52801 tatccagact cgggtcagag agcagatctt tactcatttc gtttactgcc tcaatcaacg
    52861 cagcattttt agtttgacta ttggtcccag cggttaattc actcatactc gctgacttat
    52921 ctagaacaaa aacgatatcg attggactga tttccttttt ctcgcccccg atgacatcta
    52981 gatagacatt gtaaagggtt gttgcatctt caggatgtag atcagatgct gtgctgcttg
    53041 gcagaacagg ttctacccat tttttgatgt acgccccgtt ataatccaag taactgtttt
    53101 caaaattccg ttcatttccc caaagctgaa cggtttgagc tggaacgttt ctatcttctt
    53161 cgcctgcagt tgatccatta ttagtagcat agtcgtaatt tcgccagttc gctcccccgt
    53221 ttgtataatc actatcatcg atcaagttct ctccgtcata tggcgagcct ttgtctcctt
    53281 gatagcgttc attgctttgt gtccaatttc ctaacacttt tgtatagtca ttcgttgtaa
    53341 acttcgggta gcgatgctgt tcgttttcaa cttctccgct aggatagata tattcatagg
    53401 ggtcttgcgt agctgttggc ccaagacgct ccaaaatacc gttgaataac tggcgttgaa
    53461 tgcgctggag tgcttgaccg ctgggtacga ttggttcgtc cagcttttcc atctcatttt
    53521 cttcgctacg ttgaatttca gcggaatctt ctgtatcagt ttcattttct tgtaattctt
    53581 ggttatctat tctttcatca accaccactt gaagaggtag ttacccttcg ttcacatcgg
    53641 ggatcttttc tgtttcaaaa atcaatgtgc cggtttctgc ttcttttgaa taaacttttc
    53701 cgacatacca ttcttgacca tcgatcgtct cgacttttag gtcttctcca tcttcatcat
    53761 aggaggatag acctgttcca cgaacgtttt ttacggtacc aatcccggcg gctgccgcat
    53821 cgattgctaa acgtattcta ccttcattgg cactttcctt tttttcaaaa gccagatgcc
    53881 attcaagggt ttcttctttt tcaatatact tcccttcaat ttttgcatag tcctcatcta
    53941 agaatacctc atcctccttt gtttctgttg actcagcagc tacatccagg gtcgtcatat
    54001 gatagactga ctggaaatat ggtccaaata gcaaactgac agttactaac tgcaaaagct
    54061 tcaattttaa ccctttcaca tccttatact cctttcaaaa atatttgtct tctttcacaa
    54121 caatcaacaa aacaatgccc atctaattat aatttaattt aattttaatt ttaaatcaaa
    54181 tgatatcctt tttagttaaa aa
//
LOCUS       DAZKCH010000006        53776 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000006 DAZKCH010000000
VERSION     DAZKCH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.006"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(332..835)
                     /locus_tag="ACG84X_000409"
     CDS             complement(332..835)
                     /locus_tag="ACG84X_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9126316.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1194..2219
                     /locus_tag="ACG84X_000410"
     CDS             1194..2219
                     /locus_tag="ACG84X_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFP9126317.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2542..3420
                     /locus_tag="ACG84X_000411"
     CDS             2542..3420
                     /locus_tag="ACG84X_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFP9126318.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            3896..4012
                     /locus_tag="ACG84X_000412"
     CDS             3896..4012
                     /locus_tag="ACG84X_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFP9126319.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            4940..5278
                     /locus_tag="ACG84X_000413"
     CDS             4940..5278
                     /locus_tag="ACG84X_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126320.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5372..5602
                     /locus_tag="ACG84X_000414"
     CDS             5372..5602
                     /locus_tag="ACG84X_000414"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFP9126321.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            6002..6373
                     /locus_tag="ACG84X_000415"
     CDS             6002..6373
                     /locus_tag="ACG84X_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFP9126322.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(6647..7339)
                     /locus_tag="ACG84X_000416"
     CDS             complement(6647..7339)
                     /locus_tag="ACG84X_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9126323.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(7342..8127)
                     /locus_tag="ACG84X_000417"
     CDS             complement(7342..8127)
                     /locus_tag="ACG84X_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9126324.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            8364..9764
                     /gene="lacG"
                     /locus_tag="ACG84X_000418"
     CDS             8364..9764
                     /gene="lacG"
                     /locus_tag="ACG84X_000418"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFP9126325.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            9789..10106
                     /locus_tag="ACG84X_000419"
     CDS             9789..10106
                     /locus_tag="ACG84X_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFP9126326.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            10119..11792
                     /locus_tag="ACG84X_000420"
     CDS             10119..11792
                     /locus_tag="ACG84X_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFP9126327.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            11806..13437
                     /locus_tag="ACG84X_000421"
     CDS             11806..13437
                     /locus_tag="ACG84X_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFP9126328.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(13928..15493)
                     /gene="guaA"
                     /locus_tag="ACG84X_000422"
     CDS             complement(13928..15493)
                     /gene="guaA"
                     /locus_tag="ACG84X_000422"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFP9126329.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(15552..16475)
                     /gene="coaA"
                     /locus_tag="ACG84X_000423"
     CDS             complement(15552..16475)
                     /gene="coaA"
                     /locus_tag="ACG84X_000423"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFP9126330.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            16671..17276
                     /locus_tag="ACG84X_000424"
     CDS             16671..17276
                     /locus_tag="ACG84X_000424"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9126331.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            17584..18600
                     /locus_tag="ACG84X_000425"
     CDS             17584..18600
                     /locus_tag="ACG84X_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9126332.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            18741..20042
                     /locus_tag="ACG84X_000426"
     CDS             18741..20042
                     /locus_tag="ACG84X_000426"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFP9126333.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            20088..20750
                     /gene="deoC"
                     /locus_tag="ACG84X_000427"
     CDS             20088..20750
                     /gene="deoC"
                     /locus_tag="ACG84X_000427"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFP9126334.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            20771..21169
                     /locus_tag="ACG84X_000428"
     CDS             20771..21169
                     /locus_tag="ACG84X_000428"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFP9126335.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            21235..22317
                     /locus_tag="ACG84X_000429"
     CDS             21235..22317
                     /locus_tag="ACG84X_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9126336.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            22529..24091
                     /locus_tag="ACG84X_000430"
     CDS             22529..24091
                     /locus_tag="ACG84X_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126337.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            24084..25217
                     /locus_tag="ACG84X_000431"
     CDS             24084..25217
                     /locus_tag="ACG84X_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126338.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            25217..26173
                     /locus_tag="ACG84X_000432"
     CDS             25217..26173
                     /locus_tag="ACG84X_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126339.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            26272..27438
                     /gene="deoB"
                     /locus_tag="ACG84X_000433"
     CDS             26272..27438
                     /gene="deoB"
                     /locus_tag="ACG84X_000433"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFP9126340.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            27462..28280
                     /locus_tag="ACG84X_000434"
     CDS             27462..28280
                     /locus_tag="ACG84X_000434"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFP9126341.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            28297..29004
                     /gene="deoD"
                     /locus_tag="ACG84X_000435"
     CDS             28297..29004
                     /gene="deoD"
                     /locus_tag="ACG84X_000435"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFP9126342.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(29302..29988)
                     /gene="gpmA"
                     /locus_tag="ACG84X_000436"
     CDS             complement(29302..29988)
                     /gene="gpmA"
                     /locus_tag="ACG84X_000436"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFP9126343.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(30160..30741)
                     /locus_tag="ACG84X_000437"
     CDS             complement(30160..30741)
                     /locus_tag="ACG84X_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9126344.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(30874..31557)
                     /gene="rpiA"
                     /locus_tag="ACG84X_000438"
     CDS             complement(30874..31557)
                     /gene="rpiA"
                     /locus_tag="ACG84X_000438"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFP9126345.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            31876..32289
                     /gene="rpsL"
                     /locus_tag="ACG84X_000439"
     CDS             31876..32289
                     /gene="rpsL"
                     /locus_tag="ACG84X_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFP9126346.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            32373..32843
                     /gene="rpsG"
                     /locus_tag="ACG84X_000440"
     CDS             32373..32843
                     /gene="rpsG"
                     /locus_tag="ACG84X_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFP9126347.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            32937..35024
                     /gene="fusA"
                     /locus_tag="ACG84X_000441"
     CDS             32937..35024
                     /gene="fusA"
                     /locus_tag="ACG84X_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFP9126348.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            35196..36383
                     /gene="tuf"
                     /locus_tag="ACG84X_000442"
     CDS             35196..36383
                     /gene="tuf"
                     /locus_tag="ACG84X_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFP9126349.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            36790..37098
                     /gene="rpsJ"
                     /locus_tag="ACG84X_000443"
     CDS             36790..37098
                     /gene="rpsJ"
                     /locus_tag="ACG84X_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFP9126350.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            37129..37758
                     /gene="rplC"
                     /locus_tag="ACG84X_000444"
     CDS             37129..37758
                     /gene="rplC"
                     /locus_tag="ACG84X_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFP9126351.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            37786..38409
                     /gene="rplD"
                     /locus_tag="ACG84X_000445"
     CDS             37786..38409
                     /gene="rplD"
                     /locus_tag="ACG84X_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFP9126352.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            38409..38699
                     /gene="rplW"
                     /locus_tag="ACG84X_000446"
     CDS             38409..38699
                     /gene="rplW"
                     /locus_tag="ACG84X_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFP9126353.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            38738..39571
                     /gene="rplB"
                     /locus_tag="ACG84X_000447"
     CDS             38738..39571
                     /gene="rplB"
                     /locus_tag="ACG84X_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFP9126354.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            39614..39892
                     /gene="rpsS"
                     /locus_tag="ACG84X_000448"
     CDS             39614..39892
                     /gene="rpsS"
                     /locus_tag="ACG84X_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFP9126355.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            39915..40262
                     /gene="rplV"
                     /locus_tag="ACG84X_000449"
     CDS             39915..40262
                     /gene="rplV"
                     /locus_tag="ACG84X_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFP9126356.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            40276..40932
                     /gene="rpsC"
                     /locus_tag="ACG84X_000450"
     CDS             40276..40932
                     /gene="rpsC"
                     /locus_tag="ACG84X_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFP9126357.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            40935..41369
                     /gene="rplP"
                     /locus_tag="ACG84X_000451"
     CDS             40935..41369
                     /gene="rplP"
                     /locus_tag="ACG84X_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFP9126358.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            41359..41547
                     /gene="rpmC"
                     /locus_tag="ACG84X_000452"
     CDS             41359..41547
                     /gene="rpmC"
                     /locus_tag="ACG84X_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFP9126359.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            41572..41838
                     /gene="rpsQ"
                     /locus_tag="ACG84X_000453"
     CDS             41572..41838
                     /gene="rpsQ"
                     /locus_tag="ACG84X_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFP9126360.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            41896..42264
                     /gene="rplN"
                     /locus_tag="ACG84X_000454"
     CDS             41896..42264
                     /gene="rplN"
                     /locus_tag="ACG84X_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFP9126361.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            42301..42609
                     /gene="rplX"
                     /locus_tag="ACG84X_000455"
     CDS             42301..42609
                     /gene="rplX"
                     /locus_tag="ACG84X_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFP9126362.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            42637..43176
                     /gene="rplE"
                     /locus_tag="ACG84X_000456"
     CDS             42637..43176
                     /gene="rplE"
                     /locus_tag="ACG84X_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFP9126363.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            43195..43380
                     /locus_tag="ACG84X_000457"
     CDS             43195..43380
                     /locus_tag="ACG84X_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFP9126364.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            43416..43814
                     /gene="rpsH"
                     /locus_tag="ACG84X_000458"
     CDS             43416..43814
                     /gene="rpsH"
                     /locus_tag="ACG84X_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFP9126365.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            43846..44382
                     /gene="rplF"
                     /locus_tag="ACG84X_000459"
     CDS             43846..44382
                     /gene="rplF"
                     /locus_tag="ACG84X_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFP9126366.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            44543..44899
                     /gene="rplR"
                     /locus_tag="ACG84X_000460"
     CDS             44543..44899
                     /gene="rplR"
                     /locus_tag="ACG84X_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFP9126367.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            44920..45420
                     /gene="rpsE"
                     /locus_tag="ACG84X_000461"
     CDS             44920..45420
                     /gene="rpsE"
                     /locus_tag="ACG84X_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFP9126368.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            45435..45614
                     /gene="rpmD"
                     /locus_tag="ACG84X_000462"
     CDS             45435..45614
                     /gene="rpmD"
                     /locus_tag="ACG84X_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFP9126369.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            45658..46098
                     /gene="rplO"
                     /locus_tag="ACG84X_000463"
     CDS             45658..46098
                     /gene="rplO"
                     /locus_tag="ACG84X_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFP9126370.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            46098..47393
                     /gene="secY"
                     /locus_tag="ACG84X_000464"
     CDS             46098..47393
                     /gene="secY"
                     /locus_tag="ACG84X_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFP9126371.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            47455..48102
                     /locus_tag="ACG84X_000465"
     CDS             47455..48102
                     /locus_tag="ACG84X_000465"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFP9126372.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            48293..48511
                     /gene="infA"
                     /locus_tag="ACG84X_000466"
     CDS             48293..48511
                     /gene="infA"
                     /locus_tag="ACG84X_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFP9126373.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            48544..48660
                     /gene="rpmJ"
                     /locus_tag="ACG84X_000467"
     CDS             48544..48660
                     /gene="rpmJ"
                     /locus_tag="ACG84X_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFP9126374.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            48678..49043
                     /gene="rpsM"
                     /locus_tag="ACG84X_000468"
     CDS             48678..49043
                     /gene="rpsM"
                     /locus_tag="ACG84X_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFP9126375.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            49071..49460
                     /gene="rpsK"
                     /locus_tag="ACG84X_000469"
     CDS             49071..49460
                     /gene="rpsK"
                     /locus_tag="ACG84X_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFP9126376.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            49540..50478
                     /locus_tag="ACG84X_000470"
     CDS             49540..50478
                     /locus_tag="ACG84X_000470"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFP9126377.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            50506..50886
                     /gene="rplQ"
                     /locus_tag="ACG84X_000471"
     CDS             50506..50886
                     /gene="rplQ"
                     /locus_tag="ACG84X_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFP9126378.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            51158..51997
                     /locus_tag="ACG84X_000472"
     CDS             51158..51997
                     /locus_tag="ACG84X_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFP9126379.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            51973..52842
                     /locus_tag="ACG84X_000473"
     CDS             51973..52842
                     /locus_tag="ACG84X_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFP9126380.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            52832..53629
                     /locus_tag="ACG84X_000474"
     CDS             52832..53629
                     /locus_tag="ACG84X_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFP9126381.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
BASE COUNT        17133 a         9636 c        11578 g        15429 t
ORIGIN      
        1 catagaaaat ataaagtaat tacttataaa acaagctttt tatagaaaaa taatatacct
       61 gagtagggta taaattaaga cggaattcct ttctagattg agatattgac taggaagaat
      121 gttaagattt taagccttta agctaaaaaa aaaccctttt tgttaaataa ggggaatata
      181 gcctgtcagt ttcaaactgc aagtcgtcct gctgcaataa tatagtagat tagagatgaa
      241 aatagatttt tttaaaccaa tgactgaata aaaagaccgt catagataca cattggaatg
      301 tgtctattac ggtctttttt tacgaacgat tttattgaag acggacagtt cgggtcaaaa
      361 ataaaaaagc tacgatcaga aataagaata aaatgtatcc caaaataatg gctagacggt
      421 ctaacttatt tgtcgataga tgtttgttta gaagttgata ggcccataaa cctatcagtc
      481 ctcctgttgt attagttatc aaatcagtga tgtccgctac gccaataccg aataggaatt
      541 gaatcaattc tgccaagaag cttacaagga aaataatccc taatttttta gaaaaagaaa
      601 gtctcttgaa attgacattc aaaagcaccc caaaaggaaa aaagacaatc aagttataag
      661 tggtctcacg taataccgtc gtattttcaa aagaaaaagt agaaaaaggg acgagattga
      721 cattgctgta agaataagtg agaaattgtg gaagattaaa tgatagcttg aataaaatca
      781 accataatag aaagaataaa taaatcccta ataaaaattt tgatacatac cgcatagaca
      841 tctcctccat ttaaaaagta taccatcgaa aaccgctgaa aaatcataaa aaagtatgaa
      901 gtttaaggac caacgtagtt atcgtacgaa aattagaagc ttttttttgt tgggaatccg
      961 gtttctttaa caaagctaag atagcgagtt gcttggaaaa gttgctatct tttttctgtc
     1021 aaaacgactc ggaatgttcg ttttttgttc taatttctcc aagttgttta ctttttgata
     1081 ctaagtttat gaaaaatcaa gaaatagttg ttatactagg taatgctgac aaacgggatt
     1141 ggcatttcat cttggttcag ctttttttcc aattactagg aaggagggat agattgttca
     1201 agacttattt tcgtttcaat aaaatacaag ataatccttt tcgtatcatg aatctgatgc
     1261 tacttatctt tattgtatta tggttaggtt acataaatca tgattttttg atttcaagtt
     1321 tttcatcatt agggatcttt acttttttct attatcaaaa cataccgatg aaatatttgc
     1381 tgaaacgtat gtttctgatc ggttgcggac tgttggttgc tttcgttttg gggatcttat
     1441 cgacttatgt tttatggctt gaaccatttg ccgtagcttt ggttgctttt tccagcagat
     1501 tcgtgttgcg attattccat atttctaaac caggtggctt gttttttgcg atgctttctg
     1561 ccatgggaac gagcatgcag ctgccaatcg ctcaattacc gatcgtctca ctttattttt
     1621 ttatgggtgt cgtttttgcc ctgattgcgg cagtgattac aaaattactg gattcacggc
     1681 ctgagcagac aattgaaaaa gcaactttaa aagaaagatt tcacgaagag cctttagtga
     1741 tcattgattc tgttttctac agcgctgcct tatttctttc cgtttatgtc agtcacggct
     1801 tgaatctgca taatccttat tggttgacct tgtcatgtgc atcgattttg ctagcagaaa
     1861 acttggatgc gatgaagcat cgacaagtcc aatatctgat tggatcgatg ggtgggttat
     1921 gtgtgtcggc attcttgtca tttgtgccgt ttacgcagtt gcagaccatt tttctgatca
     1981 cttttctata tggaatcgca caatttctag ttgctagaaa ttatgcagtt gctaatattt
     2041 ttcttaatcc gatggcgttg atgctatcta cacttattcg tggagcatac ttgatttctt
     2101 tgatcgaata tcgtttttta gggatcgtca taggaagttt catcggttta ggtgttgcgt
     2161 gggtaatgac ggttggtttg caacattatt taacggttgt tcgtcaaaaa ttagaataga
     2221 aggacaaata tatgtgccaa aagaggttat gacaagattt ttgtcacaac ctctaattca
     2281 aggtgttcaa aagccagatt ctcagcatta agtcaaattc acacaaaaat gtggaaagga
     2341 actttcaaaa aaattttata tttattctat caaaaaattt tgtttatgat ggtaactgaa
     2401 taaactttcc tgagatggtc aatgctttcc ttgaaagtct tacagatatt ctttcttcat
     2461 agaaagttta agttttatag ttagtgtaca ataaaagtat gtttatacca tatggtgtcc
     2521 ggataatcag tcatttaaac aatgaggttc aaagatatga aaaggggaaa tttgatgaag
     2581 aaaataagca atgaaatcca aattctggca gaaactttaa ctcttcccaa agtcgttata
     2641 gagcaaatga ttgtacaagc aaaaaacatc cttgatgagg tgtttgagca atatagtcat
     2701 gaactaatgg atcctaataa agcaaaggcg actgcaaaga aaatagacaa agtctatgaa
     2761 gaggaacctt ttgcagcatt agctatttat ctatatgcag cttctcaaag ttggaaaaaa
     2821 atttatcaac cattgaagat tccaagaact atctatttgg caacaatgaa tgcttttact
     2881 agatttattc atgaacattt ccaagtaaca ggaagctatc gctttgaccg tggtttttgg
     2941 atttggcatt acactagtgg cttgatcttt cggattggtg aattggagta cgaaatgaca
     3001 tattttccga aagggtacac ggatctaaga ttagaaggaa agcagtgcct ttctcttcat
     3061 attccttccg atgcagattt atctcagaat aagataagag atagttacga aagtgccatt
     3121 cgtttttttg aactttattt tcctgattac cattaccaag tgatgtacac agatacttgg
     3181 ttactatcac ccaatcttac taaatggttg aaaaaagagt caaaaatctg tctttttgca
     3241 gccgattatc gattattatc agttgatgaa caggacgata gtggagtccc ttggatcttt
     3301 ggacgagtag atgcccaaat acatgattat ccagaaagta cgagtttaca gcgacaagca
     3361 aaagagcaat tgcttgcagg cgagcacatt ggctctggct taggtattct tacttcataa
     3421 gtttagtact tcgaaatagt ttaaaagagc gtgagacaaa agtaaagaac acttttgtct
     3481 cacgctctaa acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa
     3541 attcacaaaa atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg
     3601 cttctgtccc agcctctttt ttagtgttct atcgaacaca cagtacgttc aataggtaaa
     3661 ctagctataa caatagatat taaagttaac ggacaagagg gcctttttta ggtagctaaa
     3721 acgtaataat gaaaatttat ttccagagat aggagtcaat cagctagtct gatcgactgt
     3781 tttaacaagt tgactttcat tttaactttt gataccattt aaaacacaaa tcgtaattgt
     3841 ttcgatttgt gttttttagc atgactacaa tcaaagaaga aagtgggtcg tccatatgga
     3901 aaaaacagat atctcaagtg cataccgccg cttgaaaagc ccaaatatca aaacacgaaa
     3961 acgtgcgctg aagatcatca aagatgtgaa acggaatagt gggaaaaggt aagaagaagg
     4021 aaacttaatt aaaaaaatag ccgaaaaacg tttttcggct attttcaata atcggttttt
     4081 gtgtaaggtt tccgaaagaa ctgctgttga ttttccattt ttaacatatg ataaattggt
     4141 agaatctttc ttttcaaatt gataccattc cctaattcca gttatatagt taactacaga
     4201 accacaaagc acgtacgttt ataaaagtat tatctgtagt tatttttcaa ttccctttca
     4261 acctcttatt ttgaccagta gtattgatca ctttaccttt taacaccttt gttcgttttt
     4321 gaaacatttt tagtcaagaa tggaaacgta actacataat caaaggtttt gcgaaatatt
     4381 tcatgaaata tttcatgtag aagcgagcaa tacggttgca aataaccatt atcgtttaat
     4441 aagcagttac gaaagctccc aatatctcta acgttcagct cactccattt cttttcttca
     4501 aaaaaatcag tgattcgtat ctctttctat ttgtcgaaaa agttaacttt aaaaagtaac
     4561 gccgaaaaaa tatgcaaaaa aataaaaaag cagttactat tgctagaata acatcaagga
     4621 ataataagtt ttggttttca gataatagtc gataagttgt gtattggaat tttagataca
     4681 gtaataaagt atttttcatg aaattttgtg agaatcacta ttacaagtat ctttaataaa
     4741 attaatggtt aaggaggaac ttaaagtaga atgtaaatga atagttgtag tcagtcgatt
     4801 gtgatactag actcaaagtt gcaggaataa gtttttcaat ttgtgattgg aagataaaaa
     4861 atgaaaaaga agggcttttt tttatacttt gttgattgta gtgtttattt tccctctgtt
     4921 tagccaagta acattttcta tgactcaacc agtttcaagt gaggaacatg ataacctttt
     4981 tcgtgctaca gaagagttta agaaatatca ggaaaatatt gttccggaga ctccattagc
     5041 tagtgagcca attactgata ttgatggaaa ccaaatagga tggtatatac agtacgaagt
     5101 tatggtggta aataatgact caatagtaaa aaatacagta ggcttagagc taacaccgat
     5161 tgaaaaggtg agttcattgt taacgtatat ttatactgat gaaagtgacg agactgagat
     5221 cattttaacg gattactcaa aaattgctac tgataaaaag tatatattgt ggatgtagac
     5281 actagtgaaa tactttatga tatagaaatt gatgaaaatt tactagatgt agcacaagaa
     5341 atcgatcatc aaaagcagga agctattcga tatgctggta gaaaagggaa aagaaaatat
     5401 ttattacgtg aatgtagcaa aagttagaga agatgaaaat gagtggaaag aattcaagag
     5461 tcgctactca attaactcga ctccgacatt tacagtttac agagaaggat cgatagaaaa
     5521 aactgttttt tggactaaag aaagtggaat gtctttagct gaagtagaag agtttttgga
     5581 ttatgttagt atgcaacagt aagggagttc ttattatgaa aaattttgac acatattatg
     5641 ttattgtttt ttcgatatct ttgctgttaa tattactaac tttaatgcag tataaagagt
     5701 atccagagta ttttatttta acttttgtat atttagtaag tagctacaca cttctatata
     5761 aattcagaag ttcttctaga gtttctaaag tttgtttctt aattagctta ttgattctat
     5821 aatatttttg atttatatag gaaattaaaa atattataga atcaacactc agagaacggg
     5881 ttggttttta atagatttaa taagtactga taatgaaatt tctcctggtt gggaaaacga
     5941 agttggttac cctgtagaag aattttttca agattacttt gcggagtatg ccgataggat
     6001 aatgagagat tacgtaacag ataaaactca agaagtcatc aatcaatccc agtcattaaa
     6061 tgaattatct gataaggcga aagaagaagc agttgccatt atttcttcag ggattagtga
     6121 ctatattgat atgagtggtg aaatcaatta tggcgataaa gacaaaattg tacgcatgat
     6181 aaaagctttt atcaaaactt ttgatgtgaa ggcagatctt aagtttaatg atacttacct
     6241 agtaggaaaa ttaattaata tccttgggac agagaaagat acggaaacgt ttatttcctc
     6301 tttgtctatg ttgtttacag ataagcattt ttcaactcag cttggtggag aggaactagt
     6361 ggaaatcttt taaccattac gcccagcatt aataaaagta tatcaaaaaa gtactcctga
     6421 tgatttttaa gattggtttg agaaataatg tgaaaacact atttttaatg ttaattatag
     6481 atagagatga acgcgtcata tggttaaaag aatgaaaaag tcaaagatac actgctatat
     6541 ttcactaagg atatagcagt gtatctttca tgtcgtttca ctggcagttt tttataaaag
     6601 gaggtgtgca tttcagttgc ttttctttgg tagttagttg aatcgtttaa gaattaacgg
     6661 atgtggcaga caggtgctct gtccaaaaac cagtaaaatc tttgatggtt ccatctttat
     6721 ttagctgtgc ctgttcaaat actgttttgt ttttaccgaa tggatcaatt gcaataattg
     6781 ttccgatccc cgcacgtttg gcagcaagta atcctgagta agcatcttcg ataacaagac
     6841 aatcagccgg agctaagctc agtttgtctg ccgctttaag aaaaatatcc ggttgcggtt
     6901 tcccagggaa agagccgtcg tcatagacaa tcttgtccca gtcaaaccag cgggctaaat
     6961 cgaaaatatc aaaataaaaa gcaacattct ctttgacagt agccgtggca atcgttaatg
     7021 gaatctgttg gtcagtcagc tggtcaagag tcgcttcaag cccttttgtc aactgaagct
     7081 cgttttcatt ttgcaagcaa agcatacgat aatagctttc tttttcttct gacaatacgg
     7141 cgatctcaga ggcggtcaaa tgctctgaaa tgaaatgttt caaaatctcc gtattcgtcc
     7201 gaccatgaat attttttaaa atatcctcgt ctgataaacc atcttttgta tgatcatgta
     7261 tcatatgcag ccaagcagct tcatgcagat gagagtccaa aaacattgtt ccgttgaaat
     7321 caaatataat ccctttcata gttacgctcc tatagtggta ttttcggttg aatcagcaat
     7381 ttgcagatcg acatattgtg catagtgctc ttgaacctcc cgcgagatct ggcgatccgt
     7441 aatgagcaga tcgaaatcat gcaaattata aaacacataa aaatcatctc gattgaattt
     7501 tttattatca acgagtagat atttcttacg ggaattattt agagcgatct gctgtgcttc
     7561 tccttcttcg gtactgtaag tagagatcgc ttcgttgtga acgccatttg aactgataaa
     7621 tgcttttgta aactttagtc ttcttaaatt gtcgttggtg atcggtccga caaatgcgcc
     7681 ggtatttttc cggaaatcac cgccaatcag tagaatttct ggtccatctg cttgagcaag
     7741 aatatcaaaa actggataat tatttgtaat gatccgaatt ttcttgttca gtaaatgcgt
     7801 cgccaatagt tcgattgttg tacctggtcc taagaaaatc gtttctccct cgtgaatcaa
     7861 ggaggctgct gtggcagcaa tttctttttt ttcttgaatc tgcagagtgg ctttttcagt
     7921 gtgagaaagt tcttgatcta aagtgtagga aagactttga gcccctccat ggacacgcag
     7981 cagcttgccc gatttttcta attcatctaa atctctgcga acggtcatat cagaaacatc
     8041 taattgattg atgatttcat taacggtaag gattcctttt ttattgacca tttctacgat
     8101 agtaagcaat ctttcttttt tcaacattgt cttcacctct aatttaagga taatctatca
     8161 tataaacgga caacagtcaa tctaattcga acaaaagtaa acatttaggg tggtttttat
     8221 gtttgttaca atagatttta ttgctgtttt ctggttttta tgattatttg tgtttgtttt
     8281 tgttgacaaa tgttttggat gcgtttacaa tgcaatcagt tagaaagagc gaaaactgat
     8341 tatagatttg aggagagatg tacatgctta aattaccaga agattttatt tttggcggag
     8401 ccacagcagc ctatcaggtt gaaggagcca ctaaggaagg tggcaaaggc gctgttgctt
     8461 gggatgactt tttagaggaa caagggcgat tcagtcccga tccggcaagt gatttttatc
     8521 atcaatatgc aaaggacatt gaattgtgtg aacgttttgg tgtaaatggt ctaagattat
     8581 ccattgcttg gagccgcatt tttcctgatg gagctgggaa accaaatcca gaaggaatcg
     8641 ctttttatca tcgtgtgttc gaagaatgta agaaaagaaa cgtaacgccg tttgtgacgt
     8701 tgcatcattt tgatacccct aaacgtttgt ttgaccatgg agattttttg aatcgagaaa
     8761 caatagaagc atttgtttcc tatgccattt tttgttttca tgaattcaaa gaagtcaagg
     8821 tgtggagtac ctttaatgaa atctatccag ttgcaaccaa tcaatatttg ttaggtgttt
     8881 tcccaccagg aatcaaatat gattttacaa agatcgtcgc ctgtcttcat aatatgatgg
     8941 ttgctcatgc ccgtgtagtg aactatttca aagaaaacga acttccgggt gaaattggtg
     9001 tagttcactc attagagacg aaatatgcgg caacagacgc gccggaagat aagcatgctg
     9061 cctttttaga cgatgcattg tcgatccgtt tcttattaga tgctacctat ttaggctatt
     9121 attcaactga aaccttgact gctcttgatg agatatgtga agcaaatcag gccagctatc
     9181 attttcctga agaagatttc gttgaattga aaaaagcatc cacgcgtaat gactacttag
     9241 ggatcaatca ctaccaatgc cattttgtca aagcttacga tggagaaaat gcaatccatc
     9301 ataacggtac gggtgaaaaa gggacctctg tttataaagt gaagggaatc ggagaacgta
     9361 tttataaaga aggaattcct cgaactgatt gggactggct gatttatcca gaaggtctat
     9421 atgacttgtt gctgcgaatt aaaagcgatt acccacatta caacaaaatc tatatcactg
     9481 agaacgggat ggggtataaa gatcagtttg aagatggcat tattatggat cagccgagaa
     9541 tcgactattt gagagtctat ttggaatcct taagcaaggc gataacagcc ggggtaaatg
     9601 tgaaggggta ttttttgtgg tcgcttatgg atcttttctc atggacaaat gggtataaca
     9661 aaaggtatgg cttgttttat gttgattttg aaacccagaa gcgttaccca aaagaatcag
     9721 cttactggta caagttggtc agtgaaacca aaacgattat ttaataagtg ataatggagg
     9781 aagaaaagat gaataaagag gaattacaaa tgcttggttt tgagatcgtt gcatattcag
     9841 gcgacgctcg cagtacatta ttgaaattat tgaaagaagt aagacaagga aactttgaac
     9901 atgttgattc ggcgttgaaa gaagccgacg aaaatttaac ccttgcacat aattcgcaaa
     9961 caaaaatttt agcggaagaa gcatctggga aagagatgga gatgggattc atttttatcc
    10021 atgggcagga tcatttaatg accactttat tgctgagaga tctgattcaa gactttattg
    10081 tactgtacag acagaatcaa ggataggaga agaacgctat ggatggaatc attaaacaaa
    10141 tcgaaaaagg gaaaccattt tttgaaaaaa tctcacgtaa tagttattta ggagccgttc
    10201 gtgacggatt tttaacagcg atgccagcta ttttattttc aagcattttc attttgattg
    10261 ctgcggttcc tgagattttt ggttaccaat ggcctgaatc tgtctccaca tggctatgga
    10321 aagtctataa ttattcgatg ggtgttgtag ggttactcgt ttcagcaacc actgctcgct
    10381 gcttggctga ttcgatgaat cgtcgcttac cgaaaaacaa agtaatcaac accacctctg
    10441 tgatgctggc ctctgtggta agtttcctgt tgttaagcgt ctctccgatt gaaggtggat
    10501 tttcaacgga atatatgggg acaaagggac tactggcttc ctttgtcgct gcatttttaa
    10561 cagttaattt atataagttt tgtgtgctga aagatattac cattaaaatg cctaaagaag
    10621 ttcctggaac gatttcgcaa accttccgag atatttttcc tttctctttt tcagtatttg
    10681 cggccgtttt aattgattta ggcattcgac aaatcttcca aatctcattt gcagaagcaa
    10741 tcattacggt gctgcagccg ctatttacag cagctgacgg gtacttagga atcgctatta
    10801 tctggggagc gatggcgctg ttttggtttg tcggtgttca tggaccgtcg atcgtggagc
    10861 cggcaattgc ggcaattatc tatgccaatg tggaaaccaa tctgcaattg ttcaattccg
    10921 gtgaacaagc ttctaaagta ctgacggtgg gtttagggaa ttttgtagga actatgggag
    10981 gaactggggc aacattggtt gttcctttta tcttcctact ctttgctaag tctaagcagt
    11041 tgaaggcagt tgggaaagct tcctttattc cagtaagttt cgctgtcaac gaaccattgc
    11101 tatttgcggc acccatgatt ttgaaccctt atttttttat tccatttttg ttaacacctg
    11161 ttgtaaacgt ttgcctgttc aagttttttg tcgatgtatt gggcatgaac agctttatgt
    11221 acgttttgcc ttgggcaact ccagcaccga tcggtttggt tctaggaacg ggcatgggta
    11281 tcttagcttt tgttctagca gcggttctaa tcgtcgttga cttcctgatc tatctaccat
    11341 tttgcaaagc atacgatgct gtcttagtag agaaagaagc acaaaaagca gaggtgatcg
    11401 caaccgagga aggtgcttct gccgatgtac gtgaggaagt acctgtggca gcgagtcaag
    11461 ttatcagcga tgcaaataaa gaaatcaatg tgttggtact ttgtgctggc gcagggacaa
    11521 gtgggatgtt agctaatgct ttaaaaaaag gtgcatctga atcgaaagca ccgatcagtg
    11581 caatggcggg tgcttatggt tctcattacg aaatgctgca ggattttgat atggtggtct
    11641 tagcaccgca agtcaattct tactatgatg atatcaaaga agacaccgat cgcttaggaa
    11701 tcaagctggt tgcgacaaaa ggagcagaat atatcggatt aacgagagat cctgaaaaag
    11761 ctgttcagtt tattctgaac caatttcaat aaaggaggag ccataatgaa aatgggaatt
    11821 tggttgcgta aagctgtttt atttgcagct gtgttagggg ctttgggggc tgtttcaaaa
    11881 actgttgaag catctgccag cgaatttatt cgcggagcag atatttcgat cctgtcagat
    11941 atggaaaaat ctggtgcaaa atattatgaa gacgatattt caaaagatgc cttagagatt
    12001 ttaaaaaata atggtgtcaa ctatgttcga ctgcgtttgt ggcaggatcc ttataatagt
    12061 aatggagaaa gttatggagc agggacaaat gatctggaaa cgacgattga ccttgcaaaa
    12121 cgagcaaaaa atctgggact taaggtgctg ctggattttc actacagtga tttttgggtt
    12181 gatcctggga aacagaatct tcctaaagca tggcaaggtc tgacctttga agaaatgaat
    12241 acggcattgt acgactatac aaagaacgtt ctgtcggaaa tgaagcagct ggacgtttat
    12301 cctgatatgg ttcagatcgg caatgaactg aatagcggaa tgctctggcc ttatggcaag
    12361 tcttggggag aaggcggggg agaatttgat cgattggctg cttttttgaa gtctggtatc
    12421 caagctgttc gagacactca acctaaaaca actccagtaa tgctccactt agctgatggt
    12481 ggcgatacag gagcatttac ttggtggttt gatgaaatca cgagtcgagg tgtgtcattt
    12541 gatttaattg gagtgtcgta ttatccgtat tggcacggtt caatgaatga acttcaaacc
    12601 aatatgaatg cgatcagcca acggtatggt aaagaagtga tcgtagttga aacagcttat
    12661 gggcatacaa cagcgaatgc cgatactatg ccaaatgctt ttggtgaagc cgaagcagct
    12721 gcggggggat atgaaccaac accgacagga caagcagagt atttgctgga tcttgccgat
    12781 cggattcagg cagtaccgaa taatcgcggg gcgggcttct tctattggga acctctttgg
    12841 tacaacggaa atgtgagttg ggcaacacaa gcaggtatga attatctcag tgttcaatcc
    12901 actatgggaa acgaatggga caaccaagcg atgtttgatt ttgctggaaa cgccttgcca
    12961 agcttgcgtg cgtttaaaca agcaggggcg caaataaatc tagttaaaaa tgcaagtttc
    13021 gaaagcgatg gaccaacgac cagtccttcc aattggcaaa cctggtttca acaaggaacc
    13081 gctaagggta cgatcaaaac ggaagcgggc actttttttg gggactacaa actaactttt
    13141 tggcaggatc aagcatacga ggcatcagct tatcaaaatg ttagtggcat aagcaaagga
    13201 acttacacat tgagtgccta tgtaatgtct gggggagagt ttgatactaa tcagttatat
    13261 atcaaaaatt atggtggagc ggaactaaat actgcggttg ttaaaacaag tgaatggaca
    13321 aaaattacaa tcaaagacat tccaattaca acaggtgttt gtgaaattgg ggtttatagc
    13381 aaggcttcag gaaatgcttg gacgaacgtt gattttgttt cattggtgaa acaatagact
    13441 gcggatcgtt tcgattcaag atcggaggtt cccttcagcc acatcgttag cgtagaaggc
    13501 aggaatcgaa cctgcacctc gcctttgcca aaaataacca gaaacgattt ccagtcattt
    13561 ttaccaaaac gagtaaagca ccagacttca tctacacttt gtattatgct aaagagagtt
    13621 caacgatttc gtaagaagca atgaaaaaat tgcaaaaagt tgtgcagata acataaagtt
    13681 tgtttaagaa agggtaacct tagaattccg tcgtgaatat gatttgagca cttagatgga
    13741 tagaaaaaag ttctcggaaa acagttcgtt tttcgagaac ttctttttat gataagaatg
    13801 aaacaaatta acttatatta tagtctcttt tggtagggaa ccatcttatt tttaatgaaa
    13861 atcaagcatt ttagctattg aagaatgttg atttataggg attccccctc catattatgt
    13921 tggctcttta ttcccactcc actgttgctg gtggtttaga agtgatgtca tacacgatac
    13981 ggttgacgtg ggctacttcg tttacgatac gtacagagat tttttgcaag acttcccatg
    14041 ggatacgggc aaagtcagcg gtcattccgt cgattgaagt tacagcacgg ataccgactg
    14101 tgtagtcgta agtacgtccg tcacccataa caccgacaga gcggatccct ggaagaacag
    14161 tgaaatattg ccagatatca cggtcaagtc cagcagctgc gatttcttca cgcaagatag
    14221 catcagattc gcgtacgatt tctagcttgt cttcagtgat ttcgccaaga acacgaatac
    14281 caagaccagg accagggaat ggctgacgcc aaacgattga atcaggcatg cctaactgag
    14341 tccctaattc acggacttcg tctttgaata atgtgtttaa tggttcgatc aattcaaatt
    14401 gcatatcttc tggcagtcca cctacattat ggtgagattt gatcgtctgt gctgtttctg
    14461 taccagattc gataacgtca gtatacaacg ttccttgtgc taggaaagag acgccttctt
    14521 caccagcaag ttttgttgct tcgtcatcaa aaacatatac gaattcattc ccaatgattt
    14581 tacgtttttg ttctgggtca gatacacctt tcaacttgtc taagaagcga tctcttgcat
    14641 tgactttgat gatgttcaag ccgaattttc cgcctagact ttccattact tgttccgctt
    14701 cgcctttgcg tagcagaccg tggtcaacaa agatagatgt caattggtca ccgatcgctt
    14761 tttgtaaaag aaccccaacg acactagaat caacgccacc tgaaagacca agcaagactt
    14821 ttttgtcacc aacttgttca cggatttttt ctacttgcat atcgataaag ttatccattg
    14881 tccagttacc ttcacagtga caaacatcaa aggcaaagtg gcgcagcaat tcgattccgt
    14941 attcggaatg acgtacttct gcatggaatt ggataccata aaaattacgt gttgtgtctt
    15001 ggatagaagc aatcggacaa tctttgcttg ttccgactgt ttcaaagcct tcaggaactt
    15061 tagttaccaa gtcaccatgg ctcatccata ctgtttgttg ttttggtgtt tctttaaaca
    15121 agacagcttg atcgcttgtt acttctaaca aggctttccc atattcgcgg tttttagcag
    15181 gctctacgga accgccaagt ttgtacgtga tcaattgcat accatagcaa atccctaata
    15241 caggaatacc taaattgaag atctcaggat cgatcccaaa tgcattctca tcatatacac
    15301 tgtttggtcc gccagaaaga atgattccct ttggattcat cgcttttact tcttctgcag
    15361 taatgcggtg gctcaataat tcggaaaaga ctccaagatc acgaatacgt cttgtgatca
    15421 attggttata ctgactaccg tagtctaata cgataatctt ttcaacgttc gtcatatcgg
    15481 caacgtttgt caaatttatt acccctatcc ctttaaattt tatctcaaaa tagtcaaact
    15541 attttaaaat gctaatattt tcgcatgaaa atcgaatcga tgatatgatt ttcagtttta
    15601 tggagaatta tatcggctct tcctcgtgta ggcaagatat attcctgtaa atttttcaaa
    15661 ttcacatttt tccatacatc ttttgccatt ttaaaggctt cttcacgatc tccgatagca
    15721 aaacgataat aataattctc tggattttgg aaagccgtat ccagtaacgc accaaaacga
    15781 tccaaatacc atttttcgat cagcacggga tcggcatcga catagacaga aaaatcaaaa
    15841 aagtcgctga cgtagatttg ctgattcgca ggtaattgaa gcgtattgat cccctcaacg
    15901 atcaagatat caggctgctg gatcaattcg tacttgtctg gaatgatatc atacacatca
    15961 tgtgagtaaa caggtacttt tatctcttcc tgaccagatt ttacacggtt caagaaatcg
    16021 atcagcatct ccatatcata actttcagga aatcctttac ggtccatgat tccacgctct
    16081 tttaatatac gatttggata aagaaatccg tcagtcgtga tcagctgaac gtttcttcgt
    16141 ttgaaggtac gagacaaaat cgtctgcagc agtctggctg ttgtactttt tccaacggct
    16201 acacttccgg cgatcccgat aataaaaggc ggtacttcta cgtatttatg aagaaataaa
    16261 cctttactca agaacaaaga ttcaaattct ttcatataaa gataaatcag atgagcaaga
    16321 ggtacataga tatctcgaac atcctgcatg gaaatgcggt cattcaaact tttgatatta
    16381 tctagttcat cttgtgtcaa aggtgcttgc ccattacgat aaaattctcg ccattcttct
    16441 cttgccacac ggtagtagtt cattggatca ttcatattag cctcctgcgt tctcccatca
    16501 atggaactat tttaacacaa aataaacgca aaccccacca cttaagagag attgccgatc
    16561 tttttgtata atctttataa tagaaagaaa cggagtctta ttcttgactt gcgcacggat
    16621 acataaaagg atagactgtt gtcatgaaag aaatgagaag gatggaagac atgacaaatc
    16681 attactattc tgaacgccca gatacggcgc acgattttga acaatgggct tttgagttaa
    16741 aaggcagaac ctttcaattt gtaacagatt ctggtgtatt ttcacgtgaa acagtggatt
    16801 atggttcacg tgtcctgatt gatgctttcg attgggaaga gttacctgat gaaggaaaga
    16861 tcttagatgt gggatgcggg tatggaccga ttgggttagc tttggcattt gcgacacagc
    16921 ggtttgttga aatggtcgac attaatgaac gagcggtaag tctagcgcaa ggaaacgcaa
    16981 agcgtaacca aatcgaacat gttgatatcc atcaatcgaa tatctatgaa gcagttcatg
    17041 aagaaaccta tgcagctatc gtaagcaatc cgccgatccg tgctggaaaa aaagttgtac
    17101 atgaaatttt gacaggcgca tatcctcggt tgaagaaggg cggtacactg acaattgtga
    17161 tccagaagaa acaaggagcg ccgagtgcgc aaaagaaaat ggaagaaaca tttggtaatg
    17221 cagaaatcgt cacaaaagat aaaggatatt atatcatcaa aagtgtgaaa gaataactag
    17281 ctgaaaaata gtggagcgac gaaagagtgg aactgggcgt gcatgtacgg gtacgtatca
    17341 gttctttttt tgttgagaag tttttaaaaa caaagaacta ttttttcttc aaaaagaaat
    17401 agtaggaaca gagtcgttgt tttttacgat aaaataaata agatacagaa cttgtataga
    17461 aggctgccaa gtcggtagat aaaggaggtt tttatcaaaa aacatacttt ccttttttct
    17521 ctattctttt cttgggggtt ttggtacact gatagggaat ttagatagaa gggagccaat
    17581 aggatgaagc tgaccatcag agatatcgca gaaatggcag gcgtatcagt aacaactgtc
    17641 tcacagattt tgaataacaa aggaagcaga tttagtgata agacaagaaa aaaagtgttg
    17701 tcgatcgtga atgaacatca ttataagccc gattatttcg cttcaaatgt gatcaatcga
    17761 cattcaaaga ccatcggaat gatcgtccct gatgtcactg atttcttctt ctccaaactg
    17821 atcgaaggtg tagagagcta tttgaatcct ttgggctatg tgatcatgtt atgcaattct
    17881 cgtcatagcc aagaaaatga gatcaagtat ttacaagagc tttcccaccg ctcagtggac
    17941 ggaatcttgc tggccacacc aaatatttta cctgagaaat atgcattaga cagcggtttt
    18001 tatcaaaaaa tgccaatcat tttaatcgat cgcggattga atcgtcggga taacggacgg
    18061 cttatcgtaa aggaatatga gggcgcctat caagctgttt cgctgtttat tgaaaatggc
    18121 catacgaaga tcggcatgct gaaggaaacc actggatact atcaattaga agaacgtttc
    18181 aacggatatc gtcatgcgct gaaagatcat ggcctgcctt ttaatgggaa atttgttgaa
    18241 catggagagt tgactgtcca aggtggatat actgcatcaa aaaaattact caaacataaa
    18301 gatatcacgg ctattttttg cgggaatgat gccatggcga tcggatgcta tcaggcgatc
    18361 gatgaattgg gcaaaaaaat cccagaagat atctcagtca taggattcga tggattaaag
    18421 ctgtcagaat acatgattcc gcaattgacg acagtgcagc agccaagttt tgatattgga
    18481 ttttatgctg cacgtttcct gatcgatacg atcgaatttc ctcaaagaaa agttccgaac
    18541 aaagtgttcg aaacaaaatt aattattcgt gagagcgtaa aagtattgac aaagggctaa
    18601 ctcggcggta tattgcttat gtaagcattt acaaaggcta gttagtgctt tttttatttt
    18661 tagtaaacca gtttactaaa gtggtttacc tttcctaaaa ataatgtata ataccgaatg
    18721 aagacaagga ggatcaggca atgcgaatgg tggatctgat tgaaaaaaag agggatggaa
    18781 acgagctgtc gaaagaggaa atcgagtaca tcgtcacgaa ctatacgaat ggaaagattc
    18841 cagattatca agtcagtgca ttattgatgg caatttttta tcaagacatg acaaatgaag
    18901 aaatcacgaa cttaacattg gcgattgcta attctggtga tgtcatcgat ttgagttctc
    18961 ttgaaggaat aaaggtagat aagcattcga caggtggcgt tggtgacacg accacattga
    19021 ttttagcccc cctagtagct agtgtcggag tgacagtggc taaaatgtct ggacgcggtc
    19081 taggttacac aggtggtaca ctagacaagc tagaagcaat tcccggattt cagatcgagc
    19141 tttcggatga agaatttgta cgcattgtta atgaaagtaa agtagcggta attggtcaat
    19201 caggaaactt ggcaccggcg gacaaaaaat tgtatgcctt gcgtgacgtc acagcgaccg
    19261 ttgattctct tccgctgatt gccagttcga ttatgagtaa aaaaatcgcg gcaggagcag
    19321 atgcaatcgt tttggatgtg accactggag acggtgcttt catgaagaac atcgaagatg
    19381 caagacgtct ggcaaagacc atgacgagca ttgggaaact ggctaaccga gaaacagtgg
    19441 cggttatctc agatatgtca gaacctcttg gcgaagctat cggaaatagt ctagaagttg
    19501 tcgaggcaat cgaaacatta caaggaaatg gtccagaaga tctagtagaa atgtgctacg
    19561 ccttaggaag ccaaatggtt gttcttgctg gcaaagctaa gacaaccgat gaagcaagaa
    19621 cgttgcttca agaagctctg gaatcaggta aagcgttagc aaaattcaaa gaaatgatcc
    19681 aaaatcaagg gggagaccca gcgatcgtgg aacatccaga acgaattttg actgcacgct
    19741 acacaatgga gcttcctgct aaacaaagcg gagttgtgtc aaaaatcgtg gcaaatgaat
    19801 taggaattgc tgcaatgatg ctaggtgctg ggcgtaaaac caaagaagaa gatattgatc
    19861 acgctgttgg attgaaactg cataaaaaaa ttggtgacac tgtgacaaaa ggtgagtcac
    19921 tattgacgat ctatagtaac gacgaagaaa tcacttctgt cattgaatta ttatataaaa
    19981 atattgaaat tggtgaatcg gcaatgaagc caacgttgat tcatgacatc atcacagaat
    20041 aaaggaaaaa agcggacttt accgttttaa agaaaagggg aaaagaaatg gaactaaacc
    20101 gaatgatcga ccatactatt ttgaaagcag acgcatctaa agaagctgtg atgcaaatta
    20161 tcgaagaagc aaaaaaatac catttttatt ctgtctgcat caatccagca tgggttgcgc
    20221 tagcgaaaga acaattacaa ggtgagccag tagccgtatg tacagtaatc gggtttcctc
    20281 taggagcaaa cacacccgag acaaaagcat ttgaaacaac agatgccatc aataacggtg
    20341 cagatgaagt cgatatggtc atcaatatcg gtgctttgaa atcaaaggat gatcaacaag
    20401 tccaaaaaga tatcgaagca gttgttgaag cagcaaaaga tcgtgcgctt gtcaaagtta
    20461 ttattgaaac atcgttatta gatagagaag aaatcatccg agcttgcgaa atagcaaaag
    20521 ctgcaggcgc tgattttgtc aaaacatcaa ctggtttctc aacaggcgga gcaaaggtag
    20581 aggatgtccg tttgatgcgt gaaactgtag gaccagaaat gggtgtcaaa gcttccggcg
    20641 gtatccataa cgaagaagaa gcaatggcaa tgatcgaagc tggtgctaca agaatcggaa
    20701 caagcgcagg agtagcaatc gtatctggtt caactggtga aggctattaa ttttttcaaa
    20761 ggagaagctc atggcagaac tcaaacaaga atggatcaac acagctattg aagcgttaga
    20821 taaagcctat gttccttatt cccattttcc ggtaggcgct tgtctcgtaa cggaatcagg
    20881 caagatttat caaggcatca acattgagaa tgcatcattt ggattaacga attgtgccga
    20941 gcgcacagct tttttcaaag cagtatctga aggagaaaaa acatttacgc atctagtcgt
    21001 agcggggcac acccccgatc ctatctctcc ttgtggtgca tgtcgacaag taatggcaga
    21061 attctgttcc cctgatatgc cggttacgct agtaggagac aatggtgtga cgaaggcaac
    21121 gaccgttcgt gcactgctgc cttatgcatt tactgaaaaa gatctataac tcatgttcat
    21181 tcagtcagct gactgttgaa aaataaaaca attattttag gaggctttac agaaatgaaa
    21241 aaagcaaaat tatttggttt aggtgctgtc gcactagcag cagggttatt tttaggtgca
    21301 tgcggcaaca acggctctac tgattcatcc ggtggcaaaa gctcatcaga cacaacaact
    21361 gcagcattga tcacagacac aggtggtgta gacgaccgtt cattcaacca gtcagcttgg
    21421 gaaggactag aaaaatgggg gaaagatcaa ggactttcac gaggaaatga tggcttccaa
    21481 tatttccaat cttcaaatga atcagattac atcccaaata ttgaccaagc attgaatgct
    21541 ggattcaaaa cgatttttgg tattggttat aaactaaaac cagcgatcca agaacaagca
    21601 acaaacaata caggtacgaa ctttgttatt atcgatgatg tcatcgatgg attagataac
    21661 gttgtatctg caactttcaa agacaacgaa gcttcttatc ttgcaggtgt tgcagcagct
    21721 tatacgactg aaacaaacgt agtcggcttt atcggcggtg taaaaggtga agtaatcgat
    21781 cgttttgatg ctggattcaa agccggtgtt gatgcaggtg cgaaagaatt aggaaaagaa
    21841 atcaaagtat tgaatcaata tgctggtgac ttctctgctc cagataaagg acgttcaatt
    21901 gctcaaggta tgtatgcaca aaacgcagat atcatcttcc atgcttcagg cggtacaggt
    21961 aacggtgtat tccaagaagc aaaatcattg aacgaatcag gcgacaaaaa agtttgggtt
    22021 atcggtgttg accgcgacca atcagacgaa ggcgaataca cattaaacgg cgaaaagaaa
    22081 aacttcacat tgacatctac actgaaagca gttggaacag tagtagaaga tttggcacaa
    22141 aaatcagcgg acggtaaatt ccctggcggc gaacacactg tttatggatt gaaagaagac
    22201 ggtgttggtc taacagaagg acaactttct gacgaagcga aaaaagcagt tgatgaagca
    22261 aaagaaaaaa tcatttcagg tgacgtaaaa gttccagaaa ctcctgaaga aaactaaaac
    22321 catttctata gccttgttag acacatgttt gacaaggcta tggtttgatt agaacaagaa
    22381 ttgttcattt atccaagctg ccttgtgaca gtttggataa gggaacaact ccctgaagta
    22441 atgtttgttt caaaagaaga acgctcacta agcgtgaatc ttagtcaatc gttgccctag
    22501 atagaaatcg ttaggatgtg aaaaaaaggt ggttcaagaa aatattgtca tagaaatgca
    22561 gaatattacc aaagaatttg gaacattcaa ggcaaatgac aacatcaatt tacaagtaaa
    22621 ggcaggagaa attcatgcgt tgcttggaga aaacggtgct ggcaaatcta cattgatgaa
    22681 cgtgctttcc ggattattag agccgacatc agggaaaatt ttgatgcgtg ggaaagaagt
    22741 aaagatcaca agtccgacca aagccaacca attagggatt gggatggtcc atcagcactt
    22801 tatgcttgtt gatgccttta ctgtaacaga aaacatcgtg ttgggaagcg agcctagtcg
    22861 cgcagggatg cttgaccata aaaaagcacg aaaagagatc caaaaagttt ctgaacagta
    22921 tggattgtca gtcaacccag atgcttacgt tcgtgatatt tcagttggaa tggaacaacg
    22981 ggtagaaatt ttaaaaacac tttaccgagg agcagatgta ctgatttttg atgagccgac
    23041 agctgtattg acccctcaag aaattgatga attaatcgtg atcatgaagg aattagtcaa
    23101 agaaggcaag tcgatcattt tgattacgca taagttagat gaaatcaaag cagtagctga
    23161 ccgctgtaca gttatccgcc gtggaaaagg aatcggtaca gtcaacgtta aagacgtaac
    23221 ctcacaacaa ttagccgata tgatggttgg aagaacggtt tcattcaaaa cgatgaaaaa
    23281 agaagcgaag cctcaagaag tcgttttgtc tattgaaaat ctagtggtga aagaaaatcg
    23341 tggattagaa gccgtgaaaa acttgaactt agaggttcgt gctggcgaag tacttggtat
    23401 cgctggaatc gatggaaacg ggcagtcgga gttgatccaa gctttgactg gtttgcgaaa
    23461 ggcagaaagc ggacatatca agctaaaagg ggaagacatc actaataaaa aaccccgaaa
    23521 aatcactgaa catggtgtag gacacgtgcc agaagaccgt cataaatacg ggttagtcct
    23581 agatatgaca ttatctgaaa atatcgcact acaaacctat catcaaaaac cttacagtaa
    23641 aaacggcatg ctgaattatt cagtaatgaa tgaacatgcc agagaattga tcgaagaata
    23701 tgatgttcga acaacgaatg aacttgttcc cgcaaaagct ttatcaggcg gaaatcagca
    23761 aaaagcaatt atcgctcgtg aagtcgaccg agatcctgat ctgttgattg ttgcaaatcc
    23821 aactcgtgga ctggatgtag gtgcgatcga atttattcat aaacgtctga tcgaacaaag
    23881 ggacaaatac aaagcagtgt tactgatcag tttcgaatta gaagaaattt taaatgtttc
    23941 ggatcgtatt gctgttatcc atgaaggaga aattgtcggt atcgttgatc cgaaagaaac
    24001 atctgaaaat gaattaggtc tattgatggc gggctatacc ttagaagaag cacgaaaaga
    24061 gttagaaaag ggggctggcg cacatgaatg atcgcagcga aaaattccgt aatttattag
    24121 tgcctgtact ttcagttgtt ttaggattga tcttaggcgc gatattgatg gctgcttttg
    24181 gttttcagcc catccaaggt tattcttcta tgctagatgc agcccttggt tcgcaaagag
    24241 ggataggtga aacgttaagg caagcaacgc cgttgatttt tacagcatta ggtttttctg
    24301 tagctaactc agctgggttt ttcaatattg ggctttctgg acaagcactt tgcgggtgga
    24361 tcgtcagtgt ctgggtggca cttgcgtttc cagatctgcc aaaagttgtt ttgcttccgt
    24421 tatgcgtgat cttaggtgcc ttagctggtg cgatggcagc ggctgttcca ggtttacttc
    24481 gagcattttt tggaacaagt gaagtgatcg taacaatcat gatgaactat atcttattat
    24541 acgtaagcac atttgcttta catgaagtga tgcctgaaag ctatcgctca agtttggact
    24601 cttccaatat gatcagtcaa aatgcctcac tgcggttacc atggttaaca caagcttttg
    24661 gcggctctcg cgtaaactca ggattatttt tagcaatcat cgcgcttatt ttcgtttggc
    24721 tgctgatgaa gaaaacgact ttaggatttg aaatccgttc tgttggattg aatccttttg
    24781 cttctgagta tgcaggaatg agtagtaaac gtacgatcgt tttgtcgatg gtcatttctg
    24841 gcgctttggc agggcttggc ggtgtggttg aaggattagg aacgtatcaa aacttctttg
    24901 ttcaaacgac ttcgctatct attggatttg acggaatggc tgtttccttg cttggttctg
    24961 gatcagcaat cggtattctt ttatcagcga tcttgttcag tattttgaag atcggtggac
    25021 ttggcatgca gacaggagca ggtgttccgt ttgagatcgt caatgtatcg attgctttga
    25081 ttatcttctt tgtcgggatc aacttcctga ttcgtttcgt catggctaaa gtcttccaag
    25141 ggaaaaaaca agaagagatc gttgcgacaa tagaatcgaa accaacgaat caaaaccatg
    25201 aagggggcga actataatgt cgactatcga attaattgcc ttgatcctta cttctacact
    25261 ggtttattca acaccgctaa ttctaacgtc actaggcgga actttttctg aacgaagcgg
    25321 gatcgtaaac gtagggctag agggaatcat ggtcatgggt gcttttagtt ccatcgtttt
    25381 caacttgacg atgagtccat cacttggttc tatgacacca tggatcgcta ttttagtggg
    25441 tggcgtcgta ggtatcctat tttctctgat tcacgcagta gcaacagtca gtttgcgtgc
    25501 tgaccatatt atcagcggga cagtaattaa tctgatggca cctgctttag gtgttttctt
    25561 gatcaaagca tggtatggta aaggtcaaac tgataacatc acgcagaatc tggggtattt
    25621 ttctttccca ggattagcag atattccggt cattggacca attttcttta aaaatacatt
    25681 cttacctgct tattgtgcta ttttgattgc tgtcctagct tgggtgatca tcttcaagac
    25741 gaaattcggc ttgcgcctcc gttcagttgg tgaaaatcct caagctgccg acacattagg
    25801 tatcaatgta tatgctatgc gttattcagg cgtactgatt tctggcttgt taggcggtat
    25861 gggcggtgct gtttttgctc agtcgatttc cggtaacttt tcagctggta cgatcgttgg
    25921 acaagggttc atctccatgg ctgctatgat ctttggtaag tggaatcctt taggggcaat
    25981 gggtgcctca ttgttctttg gttttgctca aagcttgagt atcattggcg cacaattacc
    26041 agttatttct tcgattccgc cagtattgct gcaaattgct ccatatttgc tgacaatcat
    26101 tgtgctggtt gttttcttag ggaaagcttc tggtccaaaa gcaaacggga agaactatat
    26161 caaatcaaaa taatctttta gcgaataaaa agggtgggtt acgggaagtg tttttcgtct
    26221 cgcccttttt gttttaaagg caataaaaat aaaaagaaag aaggaataat catgtttaaa
    26281 cgcgtacatc tgatcgtcat ggattcagta ggaattggag aagcaccaga tgccgataag
    26341 ttcggtgatg ttggttctga tacattagga cacattgcga aagaagcagg attgaacgtt
    26401 ccacatttag agcagcttgg tttaggaacg atccgtcctc ttgaaggtgt ggaatcagtg
    26461 aaagatcatc aaggctatgc gacgaaatta gaagaagttt ctgtagggaa agatacgatg
    26521 acaggccact gggaaatcat gggattgaat atcaaaactc catttcgtgt gtttcctaat
    26581 ggattccctg atgatctgat caaacaaatc gaagaatttt ctggccgtaa agtcgtatgt
    26641 aacaaacctt atagcggaac agctgttatt gacgattacg gtgaacacca aatgaaaaca
    26701 ggcgatttaa ttgtatatac ttctgccgat cctgtccttc agatcgcggc acatgaagaa
    26761 atcattcctt tagaagaatt atatcggatt tgccaattcg ttcgtgatat aacaaaagat
    26821 gatccgtata tgattggccg aatcattgca cgtccgtacg tgggtgaacc aggagacttc
    26881 acacgaacaa gcaatcgcca tgattatgcg ttgaatccat tcggacacac agtccttgat
    26941 tctttgaaag aagcaggaaa ggacgtgatt gctgttggaa agatcaacga tattttcaac
    27001 ggacaaggaa tcactgaatc tgtccgcacg aaaagcaata tggatggcgt tgaccagctg
    27061 ctgaaagtta tgaaaaacga tttttcagga atcagcttta ccaatttagt agattttgat
    27121 gcattatacg gtcatcgtcg ggatgtagtc ggctatgcgc atgcgattga agaatttgac
    27181 ttacgaattc cagaattgct tgaagcgatg gaagaagacg acttgctaat gattacagcc
    27241 gatcacggaa acgatccgac gtttactggt accgatcata cgcgagaata tgtaccgtta
    27301 ttggtttaca gtaaaaaaat gaaagaacaa ggggcattgc ctcaaggata ttattcagat
    27361 atttcagcaa cgattgctga gaactttagt gtttcttcga ctgaaaatgg cgaaagcttc
    27421 ttgaaattat taaaataatc tttttaaata ggagaaagca aatgaccaag ttaagcgaga
    27481 tgttacaaga aacgacccag tttatccttg ataaaggagt aaaagaaatt gattttggtt
    27541 tgattctagg ttcaggatta ggtgaattag cagatgaaat cgaagatgct gtaatgattt
    27601 cttatgatga gatcccgttc tttcctgttt cgacagtagt tgggcatgca ggaaagctag
    27661 tttatgggtc tctggcaggc aagaaagtgt tagccatgca agggagattc cactactatg
    27721 aaggtcattc catgcaaaca gtgacctatc cagtacgtgt gatggccgga ctaggggccc
    27781 attcagtcat tgtgactaat gcatgtggtg gtgtcaacga atcatttgta ccaggagatt
    27841 tgatgctgat taccgatcat atcaatttta ctggtgaaaa tcctttgatc ggtccgaatg
    27901 aagatgcaat gggccctaga tttccagata tgagtcaagc ttatacgcct gactatcaag
    27961 caacagcaaa agcagcagca gaaaaactag gtttggatct taaagaaggc gtatatatgg
    28021 gctattctgg accaacttat gaaacgcctg cggagatccg aatgtctcgg acaataggag
    28081 ccgatgcagt agggatgtcg actgttccag aagtcatcgt agcagctcac agcggattaa
    28141 aagtgttagg aatctcttgt attaccaact tagcagcagg tatgcaagcg aatctgagcc
    28201 atgaagaagt tgtagaaaca actcagagag tcaaacaatc ttttaaagca ttggttaaag
    28261 aaacattgac attattgtaa taggaggaac aataaaatga gtgtgcatat tgaagcgaaa
    28321 gaaggcgaga tcgccgataa gattttactt ccgggagatc ctttgcgagc taaatatatt
    28381 gcggagactt ttttggaaga tccagtttgt tacaatcagg tacgcggtat gttaggcttt
    28441 accggcaaat ataaaggaga acgtatttct gttcaaggaa caggaatggg aatgccatca
    28501 gccaccatct atgcccatga attgatccag tcgtatggtg taaagaaatt gattcgagta
    28561 ggtacatgcg gtgcattgtc aaaagacgtc catgttcgtg atttagtact agcacaaggt
    28621 gcagcgacca gttcttcgat gatcgaaaaa aatttccaag cctttcattt tcctccaatc
    28681 agtgatttca atctattact gaaagcatat gagatagcta aagaaaaggg ctatacggtt
    28741 catgtaggaa atgttctttc ggaagattct ttctacaaag atgatttgac agagacgttc
    28801 caattagctg aacttggcgt tttaggagtg gaaatggaag cagcggctct ttattactta
    28861 ggcgcgaaat accatgtgca gacattaagt ttgatgaccg ttagcgacca tttgatcacc
    28921 ggtgaagaaa caacagctgc agaacgtcaa tctacgttca atgaaatgat cgaagtagga
    28981 ttggaaacag cgatagcaga ataagaagga aatgaaaaag ctgccctgca ttaagtaata
    29041 agaacatcca agcaaaaata gctcctcatg tttttgactt ggctggactt attattgcaa
    29101 atgtaagctt ttgaacaccg tttaccaaga ggttgtgaat ctgccgttta actctgagtc
    29161 acaaggaaca atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg
    29221 agaagttggc aggagaaaac cgtttatacg aaaaaaggga ctgtgacaaa tcgtgtcaca
    29281 gtcccttttt tatagtgttt tttataggta gtatttttta gcaactgtta agtcatcatt
    29341 taattcataa acaagtggtt gacctgttgg aatttcaaga tccatgatgt cttcgtcaga
    29401 gataccttcg atatgtttag ctagggcgcg taatgagtta ccatgtgcag ctactaaaac
    29461 agttttgttg tctagtaatg ctggagcaat ttcatcttgc cagaatggca aagcgcgttc
    29521 taatgtcact ttcaagtttt ctccaccagg aatatcgcgt ttgtctaaca ttgcgtaacg
    29581 acggtcattt gctgcagaac cttcgtcagt ttcttccatt aatggaggaa gagtatcgta
    29641 agaacgacgc cagatgtgca cttgttcgtc gccgtatttt tcagctgttt cttttttgtt
    29701 caaaccttgt aatttaccat agtgacgttc gtttaagcgc catgatttga tttgtggtac
    29761 ccaaagttga tctgaatatt ctaagatcaa gttacatgtt ttgattgcac gagttaaaac
    29821 agaagtgtaa gcaacatcaa attcgattcc agcttctttg attttgcgtc cgccttcttt
    29881 tgcttcttcg attccttctg gtgctagatt tacatcagcc caaccagtaa attggttcaa
    29941 tgcattccat tcactaagac cgtgacgaga aaaaactaat tttggcatgt ttagctctcc
    30001 ttttaagata ggtttatatt tctgaaattt tcagttctgt tttattgtac aattttttgg
    30061 aagagatttc catcgaaaaa ttagataaga ttctatgaga aaacaagtag agaatataaa
    30121 aaaacgaaca gtgcccacgc aactgttcgt ttttaggtat tagatgcata attgctcgat
    30181 ttctttttca ggtaaattga tatatttata acatgttcca actgaaacac cgcattttga
    30241 agaaataaat tggatcgttt cttttttttc ataatagaga cgtcggattt ttttgatcgt
    30301 ttttgcatcg atttttggtc ttccgccgat ttttcctttt ttacgagctt catctaatcc
    30361 aactaatgta cgttctttga tcaatgcgca ctccatgttt gctaggtttt ccattaattg
    30421 gaaatagatt tttcccattt cgcgcgtatc gattccttca tcaagactaa tcaagtgcag
    30481 cccgcgatct ttgaataatt gcgtgagttc tgttaattgc cgcgtagatt tgcctaatcg
    30541 atgaagttgg caaatgacta gtgcatcgcc ttgttgcatg tcagcgatca ctgactccaa
    30601 atgaacagca gtagaatcat tttgttccac ttcatatgtc tcatggaaaa tttcttgaca
    30661 accaaagtca gataattgat caacctgagt tgttaaatca acgtcattta tggttgtgcg
    30721 tgcataacca ataattttca tggtgattcc tttctagcag tgattttcta actggatata
    30781 acagtaaaaa tgtagcataa agtacgtcaa aaagatagtt ttttcgcaaa ttttccgctg
    30841 tcttttttta ttggatgatc aagcagtttt tctttattta cgacggattg cgtcaagaat
    30901 ctcaacgcct ttttctgagc cgacaactac tttagaaacc atgtttagga aaagcccatg
    30961 ttctactacc ccaacaagtt catctaaata ggtagctaag ctttctggct gttcgatgac
    31021 ttctagatgc agatcaatga tgtaatgacc accatctgtg gttaagactt ctccgttttc
    31081 gtctgtacgc aagacgggtt ggaatctttt ttcttcaaaa atatgaagta gctgttggga
    31141 gccataaggg atcacttcaa ctgggagtgg gaacttccca agtttatcga ctaatttaga
    31201 agaatcaacg atccaaatcg tttcttttga gtacgtagcg actattttct cgaaaagcaa
    31261 agcagcgccg ccgcctttga tcccttgaaa atcagcactg atttcatcag caccgtctat
    31321 tgtcaaatcg actacgggga cttcatcaat actctttaac ggtattccta atttttccgc
    31381 ttgttctttt gtcgcatttg aagtagtaac tcctgtgata cgtaaacctt cttcacgcat
    31441 acggcgacca atctcttcta ccatataata ggcggttgaa ccggtcccga gacctacgat
    31501 catcccgtcc tttacgaatt tcgcggcttc aatgccagct aattgtttta aattcatctt
    31561 tgcgtccacc tttttttagt ttgagcatcg tgctttcctc actattttag cgtgatttac
    31621 ggtaaaaaga taccattctt ttttattcca ataaagcttt ttcaaaaaaa attgcatctc
    31681 ttgttgacat gttttttcat tcgtgatatt ctaacaaagg tgctttatct acaggtttct
    31741 gtgaagaaac gtgctgactg tttatcaaag catatttgat aaggatgcag acattgcatt
    31801 tattttttat cacaaaaaaa gaaccacctg gatgtgtgga actagacgca aatcgtggga
    31861 aggaggaaac aaggaatgcc tacaattaac caattagtac gtaaacctcg taaatcaaag
    31921 gtggaaaaat ctaattcacc tgctttgaac aaaggatata acagctttaa gaaaactcaa
    31981 actaacgtaa actcacctca aaaacgtggg gtagcaactc gtgtgggtac aatgacacct
    32041 aaaaaaccga actcagcttt acgtaaatat gcacgtgttc gtttgtcaaa cttaattgaa
    32101 gttactgctt atatcccagg gattggtcat aacttacaag aacacagtgt tgtattatta
    32161 cgcggtggtc gtgtaaaaga cttaccaggg gtacgttacc atatcgttcg cggtgcttta
    32221 gatactgctg gtgttaacga ccgtaaacaa agccgttcta aatacggaac taaaaaacct
    32281 aaagcttaat tttaattatt aaacaaatga aacttgcttc tactatatag aagtaattac
    32341 tatgaacaat atttcggaag gaggagttac ggatgccacg taaaggtcct gttgcaaaac
    32401 gtgatgtttt accagatcct atttataact caaaattagt aactcgcttg atcaaccgtg
    32461 taatggttga cggaaaacgc gggattgcag ctaacattat ctataatgcc tttgacttga
    32521 tcaaagaatc tacaggtaac gatccattag aagtgtttga acaagcaatg aaaaacgttc
    32581 aacctgttct tgaagttaaa gcacgtcgtg ttgggggttc aaactaccaa gtaccagttg
    32641 aagttcgccc tgaacgccgc gttactctag gtcttcgttg ggtagtaaac tacgctcgct
    32701 tgcgcggtga acacacaatg gaagaacgct tagcaaaaga aatcatggat gctgcaaaca
    32761 acacaggtgc ttctgttaaa aaacgtgaag acactcataa aatggctgat gccaaccgtg
    32821 cgtttgctca ctatcgctgg taagattctc tctgtttggt cggcttttat aagtcgacct
    32881 cagatagtgt ccttattttt agcaactaga tagtaaagag aggagaaaca aggagaatga
    32941 ccagagaatt ttctttacaa aacactcgta atatcggtat catggcccac atcgatgctg
    33001 gtaaaacgac tgctactgaa cgtatcttgt actatactgg taaaatccat aaaattggtg
    33061 aaactcatga aggagcttca caaatggact ggatggaaca agaacaagaa cgtggtatta
    33121 cgatcacttc tgctgctact acagcacaat ggaagggtca ccgaatcaac atcatcgaca
    33181 caccaggaca cgtagacttc acagttgaag ttgaacgttc attgcgtgta cttgatggtg
    33241 ctgtaactgt tcttgatgca caatcaggtg ttgaacctca aactgaaaca gtttggcgtc
    33301 aagcaacaac ttatggtgta cctcgtatcg tatttgcaaa caaaatggac aagatcggtg
    33361 ctgacttctt atattcagta tcaactttac atgaccgttt gcaagcaaac gctcacccaa
    33421 tccaattacc aattggtgcg gaagacgact tcacaggaat tatcgacctt gtaacaatga
    33481 aggctgaaat gtatacaaac gatcttggaa cagagatcga agaaacagaa attcctgaag
    33541 aataccgcga attagctgaa gaatggcgcg aaaaattggt tgaagctgta gctgaaactg
    33601 atgaagaact tactttgaaa tacttagaag gtgaagaaat cactgaagct gagttaaaag
    33661 aaggtatccg ccgcgcaaca gttaacgtag aattctaccc agtactatgt ggttcagcat
    33721 ttaagaacaa aggggttcaa ttactattgg acgctgttct tgattacttg ccatcaccgt
    33781 tagatatccc agctatcaaa gggattgacc ctaaaactga tgaagaagta gaacgtcctg
    33841 cagacgacag cgctcctttc tcagctttag catttaaagt tatgactgac ccattcgtag
    33901 gtcgtttaac tttcttccgt gtgtactctg gtgttttaca atcaggttca tacgtacaaa
    33961 acgcaacaaa aggcaaacgt gaacgtgttg gtcgtatcct acagatgcat gccaactctc
    34021 gttcagaaat ctctgaagtt tacgctggag atatcgctgc tgctgttggt ttgaaagaca
    34081 caactactgg ggacacacta tgtgatgaaa agagtctagt tattcttgaa tccatggaat
    34141 tcccagaacc agttatccaa gtcgctattg aacctaaatc aaaagctgac caagataaaa
    34201 tgggtgtggc tttacaaaaa ctatctgaag aagatcctac tttccgtgct gaaacaaacg
    34261 tggaaacagg cgaaacaatc atcgctggta tgggtgaact tcacttagat atcatcgttg
    34321 accgtatgcg tcgtgaattc aaagttgaag ctaacgtagg tgcgcctcaa gtatcttacc
    34381 gtgaaacttt ccgtgctggc actcaagccg aaggtaagtt tgtacgtcag tctggtggta
    34441 aaggtcaata cggtcacgta tggattgaat ttacaccaaa tgaagaaggt gctggtttcg
    34501 aatttgaaaa tgcgatcgtc ggtggggttg ttcctcgtga atacattcca gctgttgaaa
    34561 ctggtttgaa agatgctatg gaaaatggtg tcttagctgg ctatccatta gtagatatca
    34621 aagctaaact ttacgatggt tcataccatg atgtcgattc aaatgaaact gccttccgtg
    34681 ttgctgcttc tatggcatta cgtgcagcag ctaagaaagc taatccagta atccttgaac
    34741 caatcatggc tgtagaagtt gttatccctg aagattattt aggtgatgtt atgggtcacg
    34801 taactgctcg tcgtggacgt gttgaaggta tggaagctcg cgctggcggc caacaagttg
    34861 ttcgtgcgat ggttccactt gctgaaatgt ttggttatgc tacaactctt cgttctgcta
    34921 ctcaaggtcg tggtacattt acaatgacat ttgaccacta cgaagatgta ccaaaatcag
    34981 tacaagaaga aatcattaag aaaaacggcg gaaaagctga ataatttctt gaaaccggat
    35041 agtcctgcaa agagattatc caaagagact atatttttaa tatagtttcg tgtaaaataa
    35101 ttatcgatga tatgggcatg tggtgtacct tgtgtacatc atatacctat cagacaaata
    35161 aaaaatatat tgtattttta ggaggacatt ttaaaatggc aaaagaaaaa tttgaccgtt
    35221 ctaaaccaca cgttaacatt ggtactatcg gacacgttga ccatggtaaa actacattaa
    35281 cagctgcaat cacaactgta ctatctaaga aaaacggcgg ccaagctatg gcttacgatc
    35341 aaatcgatgg tgctccagaa gaacgcgaac gcggaatcac aatctcaaca gctcacgttg
    35401 agtatgaaac agatacacgc cactacgctc acgttgactg cccaggacac gcggattacg
    35461 ttaaaaacat gatcactggt gctgctcaaa tggacggagc tatcttggta gtttctgctg
    35521 ctgacggccc aatgcctcaa actcgtgaac acatcctatt gtctcgtcaa gttggtgttc
    35581 cttacatcgt tgtattcttg aacaaagtag acatggttga tgacgaagaa ttactagaat
    35641 tagttgaaat ggaagttcgt gacctattaa cagaatacga attccctggt gacgatgttc
    35701 ctgtagttgc tggatcagct ttgaaagctc tagaaggcga cgcttcatac gaagaaaaaa
    35761 ttcttgaatt aatggctgca gttgacgaat acatcccaac tccagaacgt gacaacgaca
    35821 aaccattcat gatgccagtt gaagacgtgt tctcaattac tggacgtggt actgttgcta
    35881 caggtcgtgt tgaacgtgga caagttcgcg ttggtgacga agttgaagtt gttggtattg
    35941 ctgaagaaac ttcaaaaaca acagttactg gtgttgaaat gttccgtaaa ttgttagact
    36001 acgctgaagc tggagacaac attggtgctt tactacgtgg tgttgcacgt gaagacatcc
    36061 aacgtggaca agttttagct aaaccaggta caatcacacc tcatacaaaa ttctctgcag
    36121 aagtatacgt gttgacaaaa gaagaaggtg gacgtcatac tccattcttc actaactacc
    36181 gtccacaatt ctacttccgt acaactgacg taacaggtgt tgttgaatta ccagaaggaa
    36241 ctgaaatggt tatgcctggc gacaacgtaa caatggaagt tgaattaatc cacccaatcg
    36301 ctatcgaaaa cggtactaaa ttctcaatcc gtgaaggcgg acgtacagtt ggtgccggtg
    36361 tcgttacaga aatcaaagct taattcactt aagttttaaa gtaaagcaac atttattcgg
    36421 acgtaatcgc tcggaacgaa ggtcttagga tctttgttcc gagctttttt atttattgca
    36481 ggatcaggaa aaaagacagg agtattataa atagaagaaa cacgaaataa aagagtcagt
    36541 attttctaaa tgaaacttta tgaaaacaaa atgtttttta caagaaaaag ccttgctttg
    36601 tgagtttata tatattataa tgacaaaggt gcgtttactt tagtgaattg cacagacgta
    36661 atcagaatga tttcgtcggc taagaaacga gaggttgcga cacgcccgga cgctttgcca
    36721 cgaacgagcg tgacggaaat tttcgtggag ctatgtctac ttttcaaaat aggcgaagga
    36781 gggaacaaga tggcaaaaca aaaaattcgt atccgtttaa aagcgtatga acaccgtatt
    36841 ttagatcaat cagcggataa aatcgtggaa actgcaaaaa gaactggagc tagcgtgtct
    36901 ggtccaattc cattaccaac tgaacgcagt ctttacacaa tcatccgtgc gactcataaa
    36961 tacaaagatt cacgcgaaca attcgaaatg cgtacacaca aacgtcttat cgacattgtg
    37021 aacccaacac caaaaactgt tgatgctttg atgaagctag acttaccatc tggtgtaaac
    37081 atcgaaatca aattataaaa ctaaaacaaa aataatggag gtgtactcat gaccaaagga
    37141 atcttaggga aaaaagtggg aatgacacaa atcttcactg aatctggtga attaattcca
    37201 gtaactgttg tagaagctac tccaaacgta gtactacaag tgaaaacaat ggaaacggat
    37261 ggctacgaag ctattcaagt tggttaccaa gatatgcgtg aagttttatc aaacaaacct
    37321 gcgaaaggtc atgttgcaaa agcaaacacg gctcctaagc gcttcattcg tgaattcaaa
    37381 aatgttgagc taggagaata tgaagtagga aaagaaatta cagtagatgt tttccaagca
    37441 ggagacatta ttgatgtaac aggtactacg aaaggtaaag gattccaagg ggttatcaaa
    37501 cgccacggac aaagccgcgg accaatggct cacggttctc gttaccatcg tcgtcctggg
    37561 tcaatgggtc cagttgcacc taaccgtgta tttaaaaaca aacgtcttgc tggccgtatg
    37621 ggtggcaacc gcgtaactat ccaaaacttg gaagttgtac gtgtcgatgc agaaagaaat
    37681 gttatcttga tcaaaggtaa tgttcctgga gctaaaaaat ctttaattac tatcaaatca
    37741 gctgtgaaag ctaaataatt gtaggaagaa aggaggaact aaggaatgcc gaatgtagca
    37801 ttattcaaac aagatggaag ccaaaacggt gaaatcacac ttaacgaaga aatcttcgga
    37861 attgaaccta atgaaagtgt tgtttacgat gcaatcgtaa tgcaacgtgc gtcattaaga
    37921 caaggaacac acgcggttaa aaaccgtagc gctgttcgcg gcggcggacg taaaccatgg
    37981 cgtcaaaaag gaacaggtcg tgcacgtcaa ggatctatcc gctcaccaca atggcgtgga
    38041 ggtggcgtag tctttggacc aacaccacgt tcttacagct acaaacttcc taaaaaagtt
    38101 cgtcgtttag caatgaaatc tgtattgtca gaaaaagttg ctgaaaacaa cttggtagca
    38161 atcgaaggct tgaacttcga cgcaccaaaa acaaaagaat tcaaacaagt tcttgctaac
    38221 ttatctatcg actctaaagt attggttgtt ctagaaaaag gtaacgactt tgctgcttta
    38281 tcagcacgta acttaccaaa cgtttctgta gtaacttctg ataatgtgag tgtgctagac
    38341 gttgtatcaa atacaaaagt gttagcaaca caaactgctc ttactcaaat tgaggaggtg
    38401 cttgcataat gaacttacta gacgtaatca aacgcccagt gatcactgaa aaatcaatgc
    38461 ttgccatgga tgacaagaaa tacacttttg aagtggacac tcgcgcaaac aaaactttag
    38521 taaaacaagc ggtagaagct gcttttgacg ttaaagtcaa aaacgtgaac atcgtgaacg
    38581 tacgtgcgaa attcaaacgt atgggcaaat atgcaggata tacaaaaaaa cgtcgcaaag
    38641 cgatcgttac attgactgaa gattcaaaag aaatccaatt attcgaagct gctgaataag
    38701 cactaataga taactcatta aattaggagg gaaaaacgtg gcgattaaaa agtacaaacc
    38761 tacctcaaat ggtcgtcgta acatgacagg ttctgatttt gctgaaatca caacatcaac
    38821 acctgaaaaa tcattgttac aaccattgaa aaaccatgct ggacgtaaca acaacggccg
    38881 catcactgta cgtcatcaag gtggcggaca caaacgccaa tatcgcgtga tcgacttcaa
    38941 acgtaacaaa gataacgttg ttgcaactgt tcaaacgatc gaatatgatc caaaccgttc
    39001 agctaacatc gcgttagtac actatgaaga tggagtgaaa gcttacatct tagcacctaa
    39061 aggactagaa gtgggtatga aacttgtttc aggtccagaa gcagatatca aagtcggaaa
    39121 tgctcttcca ttagaaaaca ttccagttgg tactgttatc cacaacattg aaatgaaacc
    39181 tggtaaaggt ggacaattga tccgttctgc tggtacaagt gctcaagtac ttggtaaaga
    39241 aggcaaatac gtattgatcc gcttgaactc tggtgaagtt cgtatgatct tagctgcatg
    39301 ccgtgctaca atcggttctg taggtaacga acaacacgaa ttaatcaaca tcggtaaagc
    39361 tggacgctct cgttggatgc gtaaacgccc aactgtacgt ggtagcgtaa tgaaccctaa
    39421 tgatcaccca cacggtggtg gtgaaggtaa agctcctatc ggacgtaaag caccagtttc
    39481 tccttggggt caaccagctc ttggttacaa aactcgtaac aaaaaagcta aatcagacaa
    39541 acttattgtt cgtcgtcgca aaaataaata attactttga ccatgtgtcg cacattttga
    39601 gaggaggttc accatgggtc gtagtttaaa gaaaggacct tttgtcgatg agcatttaat
    39661 gaaaaaagtt gaagctcaag caggggttga aaagaaaaaa gttatcaaaa cttggtcacg
    39721 ccgttcaaca gttttcccaa gttttgttgg atataccatc gcagtttatg atggacgtaa
    39781 acatgtacca gtttacatcc aagaagacat ggtaggacac aaattaggtg aatttgcacc
    39841 tacaagaact tatcgtggac atgctgctga cgataagaaa acgaaacgct aatttgaggg
    39901 gaggataaat ccaaatggca gaacaaatca catcagctaa agcaactgca aaaacagttc
    39961 gcacttcacc tcgaaaagcc cgtttagtaa ttgaccttat cagaggtaaa agtgtcgcag
    40021 atgcaatttc aatcttgaaa ttcacaccaa acaaatctgc tggaatcatt gaaaaagtat
    40081 tgatgtcagc agttgcgaat gcagaaaata actttgactt agatgttgaa aacttggtag
    40141 taagcgaagc ttttgttaac gaaggaccta caatgaaacg tttccgtcct cgtgcaaaag
    40201 gatcagcttc tccaatcaac aaacgtacaa gtcatatcac ggtagtcgta tcagaaaaat
    40261 aaggagggat aatcagtggg tcaaaaagta catccaattg gaatgcgtgt aggcatcatc
    40321 cgcgactggg atgctaaatg gtatgctgaa aaagagtatg ctgagttctt acacgaagat
    40381 ttaagaatcc gtaaatttat ttcaactaaa cttgctgatg ctgctgtatc aacagttgaa
    40441 atcgaacgcg caacaggtcg cgtaaacatt tcaattcaca cagctaaacc aggtatggtt
    40501 attggtaaag gcggttctga agtcgaaagc ctaagaaaag aattaaacaa attaactggt
    40561 aaaagaatcc atatcaatat cgtggaaatc aaaaaaccag atctagatgc aaaattagta
    40621 ggtgaaggaa tcgcacgtca attagaaaac cgtgttgctt tccgtcgcgc tcaaaaacaa
    40681 gccatccaac gctcaatgcg tgctggcgct caagggatca aaactcaagt atctggtcgt
    40741 ctaaacggag cagatatcgc tcgttcagaa ggatactcag aaggaactgt tcctcttcat
    40801 actttacgtg cggacattga ttacgcatgg gaagaagcag atacaacata cggaaaacta
    40861 ggagttaaag tgtggatcta tcgtggagaa attcttccaa ctaaaaaaaa cactgagaaa
    40921 ggagggaaat aatcatgtta gtacctaaac gtgtaaaaca ccgtcgtgaa ttccgcggaa
    40981 aaatgcgcgg ggaagctaaa ggcggaaaag aagtagcatt cggtgaatac ggtttgcaag
    41041 ctgttgattc acattggatc acaaaccgcc aaatcgaagc tgctcgtatc gcaatgactc
    41101 gttacatgaa acgtggtggg aaagtatgga ttaaaatttt ccctcacaaa tcttatactg
    41161 ccaaagcaat tggggtacgt atgggttctg gtaaaggggc acctgaagga tgggttgcac
    41221 cagtaaaacg tggtaaaatc atgtttgaaa tcgcaggcgt tcctgaagaa gtagctcgtg
    41281 aagcgttacg tctagcttct cacaaattac caatgaaaac taagatcgta aaacgtgagg
    41341 aaatgggtgg tgaatcgaat gaaggttaaa gaaatcagag aattaaccac tgccgaaatg
    41401 cttgatcaag aaaaacaatt aaaagaagaa ttgtttaatc ttagattcca attagcaaca
    41461 ggtcaattag aaaacactgc acgtattaaa gaagtacgta aatcgattgc acgcatcaaa
    41521 actgtgttgc gtgaacaagc taagtaatta tggaaggagg ccattaagcg tatgactgaa
    41581 ggaagaaatc aacgcaaagt ttatcaaggt cgcgtggttt cagacaaaat ggataaaaca
    41641 attaccgttg ctgtcgaaac aaagaaaaac caccctatct atggcaaacg catgaactat
    41701 tctaagaaat acaaagtgca tgatgaaaac aacacagcaa aagttggcga catcgtgaga
    41761 attatggaaa ctcgtccatt atcagctaca aaacgtttcc gtttgttgga agtagtcgaa
    41821 gaagcagtta ttatctaata acacgagatt ttcctatata gattgaatgc aaaatctgaa
    41881 aggaggatac acaacgtgat ccaagcagaa agtcgtttaa aagtcgctga taactcaggc
    41941 gcacgtgaaa ttttgacgat caaagtcctt ggtggatctg gtcgtaaaac tgctaacatc
    42001 ggtgatgtga tcgttgctac ggttaaacaa gcaacgccag gtggggttgt caaaaaaggt
    42061 gacgtcgtta aagccgttat cgttcgaaca aaatcaggag ctcgtcgtac agacggttca
    42121 tatattaaat ttgatgaaaa tgctgcagtg attattcgtg atgataaaag ccctcgtgga
    42181 acacgtatct ttgggccagt tgcacgtgaa ctacgtgaaa acaacttcat gaagatcgtt
    42241 tcactagcac cagaagtttt ataatcttga gacacttatc aaaggaggtg cgaaacagtt
    42301 atgtttgtta aaaaaggcga taaagttaaa gttatcactg gaaaagacaa aaacaaagaa
    42361 ggcgttgtac tagcagcgtt cccgaaaaaa gataaagtta ttgtcgaagg tgtaaatgtc
    42421 gttaaaaaac accaaaaacc ttctcaagct gctcctcaag gtggaattgt tgagatggaa
    42481 gcgccaattc atgtttctaa cgtgatggtg gttgactcta ctggtgtagc tggccgagtt
    42541 ggctacaaag aagtagacgg caaaaaagtc cgtgtttcta aaaaaaccgg tgaagtttta
    42601 gataaataaa agtttaagga aggagggtct tactgaatga accgcctaaa agaaaaatat
    42661 cttaaagaag taactccatc attgatggaa aaatttaact atagctctgt tatgcaaaca
    42721 cctaaagttg aaaaaatcgt catcaacatg ggtgttggtg atgcggtatc aaacgctaaa
    42781 aacttagata aagcagttga agaattaact ttgatcactg gtcaaaaacc aatgattaca
    42841 aaagctaaaa aatcaatcgc tggattccgt ttacgtgaag gaatgccaat tggtgcaaaa
    42901 gttacattgc gcggagaaag aatgtacgaa ttcttagaca aattggtttc tgtttcacta
    42961 ccacgtgtac gtgacttcca tggtgtaagt aaaaaagcct ttgacggtcg tggaaactat
    43021 actttaggta ttaaagaaca attgatcttc ccagaagtag attatgattt agtagataaa
    43081 gtacgtggta tggacatcgt tattgtaaca acagcaaact ctgatgaaga atctcgtgag
    43141 ttgttgacac aattaggcat gccattccaa aaataattaa aggaggcgaa ctacgtggct
    43201 aaaaaatcaa tgattgctaa aaacaaacgt cctgcaaaat tttcaacaca agcttatact
    43261 cgttgcgaac gttgcggacg tccacattca gtttatcgta agttccatct ttgccgtatt
    43321 tgcttccgcg aacttgccta taaaggtcaa attcccggcg tgaagaaagc tagctggtaa
    43381 aaagtaaatt cgcataagaa ggaggtaaaa gatcaatggt catgacagat ccaattgcag
    43441 attttctaac tcgtatccgt aacgcaaaca tggttaaaca tgagtcttta gaagtacctg
    43501 catcaaaaat taaacgtgac atcgctgaaa tcttgaaacg tgaaggtttc gttcgtgatg
    43561 ttgaatacat cgaagatgac aaacaaggcg tgatccgtgt tttcctaaaa tttggtaaaa
    43621 acggcgaacg tgttatcaca aacttaaaac gtatctctaa accaggtttg cgtgcttatg
    43681 tcaaagctga cgaagtacca aaagtattga acggtttagg tatcgcaatc atttcgactt
    43741 ctgaaggtgt tgtcactgat aaagaagctc gtgaaaaaaa tatcggcggc gaagttatcg
    43801 cttacgtatg gtaatcaagt agaatctaca aggaggtgtc tttaagtgag ccgtatcgga
    43861 aataaagtcg ttgttatccc tgaaggagta acagttactc aagacggaaa caacgttaca
    43921 gttaaaggac caaaaggtga attgactcgt actttttcag cagatatcaa aatgaatatc
    43981 gaaggaaacg aagtaacttt cactcgtcca aacgacagta aagaaatgaa aacaattcat
    44041 ggaacaactc gtgcgaactt caacaacatg gttgtaggtg tcagcgaagg tttccaaaaa
    44101 gcgttagaac taatcggggt tgggtaccgt gcacaattac aaggatcaaa acttgtattg
    44161 aacgttggtt actcacatcc agtagaaatc acaccaccag ctggagtaac tgttgaagta
    44221 ccagctaaca cacaagtaat tgttaaaggt gcgaacaaag aagaagttgg cgaattagct
    44281 gcaaacattc gtggaactcg tcctccagaa ccttataaag gtaaaggtat tcgttatgtt
    44341 ggcgaatatg tacgccgtaa agaaggtaaa actggtaaat aatcgtttag aaaaattgca
    44401 tagaagccag cagcaggaaa aaggcatttg gctgaagttt accttcaaaa aaatacattt
    44461 ttacttgtgc cgcagcttct atttttcgaa acgtatttac tgcttgaaat agtagtacaa
    44521 taaaaataaa gaggtgacaa ttgtgattac aaaaccagat aagaacaaaa cacgtcaaaa
    44581 gagacatcgt cgtgtacgta acaatatctc tggtactgct gagcgcccac gcttgaacgt
    44641 ttttcgttct aacaaaaaca tctacgctca aattattgat gacgtagcgg gtgtaacgct
    44701 agcaagtgcc tctaccttgg ataaagaaat ttcaggtgga acaaaaacag aagcagcaca
    44761 agctgtcggt aaactagttg ctgaacgtgc agctgaaaaa ggcattaaag tagtagtctt
    44821 tgaccgtggt ggataccttt accatggccg tgtgcaagct ttagctgaag ctgctcgcga
    44881 aaatggacta gaattttaga agaaggagga ataccattca tggtttatat cgatccaaaa
    44941 catttggaat tagaagaccg cgttgttgca attaaccgtg taacaaaagt tgttaaaggt
    45001 ggacgtcgtc tacgttttgc tgctttagtt gttgtcggtg acaaaaacgg acacgtagga
    45061 tttggtacag gtaaagctca agaagttcct gaagcaatcc gtaaagcaat tgaagatgcg
    45121 aagaaaaact tagttgaagt acctatggtt ggttcaacaa tcccacacga agtaatcggt
    45181 gcttttagtg gtggtagaat cctaatgaaa cctgctgtag aaggttctgg ggttgctgct
    45241 ggtggaccag ttcgtgccgt attagaatta gctggggtag cagatatcac ttctaaatct
    45301 ttaggctcaa atacaccaat caacgttgtt cgcgcaacag ttgaaggttt gaaacaattg
    45361 aaacgtgcag aagaagttgc agaacttcgc ggcaaatcag ttgaagaatt aatcggataa
    45421 ggaggacaac aataatggct gaattaaaag ttactttaaa acgcagtatt atcggacgtc
    45481 ctcaaaacca acgcgataca gttaaagcgt taggtcttac aaagattaac agttcagtgg
    45541 ttaagccttc taatgaagca attaaaggca tgatcaatac tgtttctcac ctagtggacg
    45601 ttgaagaaat ttaatttaga aaaatcataa ctagaacatt aaggaggtgc caaacctatg
    45661 aaacttcatg aattaaaacc tgctgaaggt tcacgccaag tacgtaaccg tgttggtcgt
    45721 ggtacttcat ctggtaacgg aaaaactgcc ggacgcggac aaaaaggaca aaaagctcgt
    45781 tcaggcggcg gtgtgcgttt aggatttgaa gggggacaaa caccattgtt ccgtcgttta
    45841 ccaaaacgag gattcacaaa cgtgaaccgt aaagactatg cagtcattaa tcttgatgta
    45901 ttgaaccgct ttgaagacgg agctgaagta actcctgttg ctttagttga agctggaatc
    45961 gtgaaaaacg aaaaagctgg aatcaaagta ttagctaatg gggaactaaa caagaaatta
    46021 actgtgaaag cagcaaaatt ctctaaagca gctcaagaag caattgaagc ggctggtgga
    46081 tcaatcgagg tgatctaatg tttagactat taaaagatgc ttttaaagta aaagacatta
    46141 gatcgaaaat cctatttact gtatttgtgt tgtttgtatt tcgcctaggt gcacatatta
    46201 ctgtaccagg cgtaaatgct gcttcattgc aaaacctttc ttctttgcca tttttcaaca
    46261 tgttgaactt ggtaagtggt agtgcgatgc aaaacttttc cattttctca atgggggttt
    46321 caccatacat tactgcttct atcgtcattc agcttcttca aatggacatc gtgcctcgat
    46381 ttgttgaatg gtcgaaacaa ggggaagttg gtcgtaaaaa actgaatcaa gcgactcgat
    46441 atctgacatt agtattggca tttatccaat ctgtcggtat cactgctgga ttcaatcaat
    46501 acgctcaatt aggtttcgtg aataatccta acgtagcaac ttacgtaacg atcggtttga
    46561 ttctaacagc cggtacgatg tttgttactt ggctaggaga acagatcaca gaaaaaggta
    46621 tcggaaatgg cgtatcaatg atcatttttg caggtatcat ttctagattg cctgaaagta
    46681 tcagagaaat ttatgaagat tactttataa atattgatcc ttcagacata tggaaatctg
    46741 ctatttttgt ggccatttta ctagtagcgg tcttgttgat cgtgacattc gtaacatttt
    46801 tccaacaagc tgaacgcaag atcccgatcc aatatacgaa acgcgtagct ggcgcgccta
    46861 caagcagcta tctgccgttg aaagtaaatg cagctggagt tattccagtt atctttgcta
    46921 gttcgtttat tgctacgcca aatgctgttt tacaagcatt gagcggtaga ttcggttctg
    46981 aaaactggta caaagtgatg atggagatct ttaactataa tacagcacct ggtgctacga
    47041 tttatacgat tctgatcgtt gccttcactt tcttctacgc ctttgttcaa gtaaaccctg
    47101 agaaattagc ggaaaacttg caaaagcaag gaagttatat accaagcgta cgccctggta
    47161 aggggactga agagtatgtc tcaagattac tgatgcgttt aagtacagtt ggtgcagtct
    47221 tccttggttt agtggcattg cttccaatca ttgctcaaat ggtttgggat cttccacaat
    47281 caatcggatt aggcggtaca agcttactga tcgttatcgg tgtagcttta gaaactgcga
    47341 aacagttaga aggcttaatg ctgaaacgta aatatgttgg attcattgag taagaaagcg
    47401 tgttgaggtt tcccctcaac acacgttctc acacatttat taggagggaa aacaatgaac
    47461 ctcattttaa tggggctgcc aggcgcaggt aaaggaacac aagctgaaaa aatcattgat
    47521 gcttatggta ttccgcacat ctcaacagga gatatgttcc gcgcagcgat gcaaaacgaa
    47581 acagctcttg gcctggaagc aaagtcttat atggataaag gtgcattagt tcctgatgaa
    47641 gtaacaaatg gaatcgtgaa agagcgacta gctgaaccag atacagagaa aggcttctta
    47701 ttagatggct ttccacgtac gctagatcaa gcaaaagctc tggacgcaat gctaaaagat
    47761 ttgaataaaa aaattgatgc tgtcatcgat atccatgttg gtgaagaaat cttggtcgaa
    47821 cgtctagccg gccgatttat ctgcagcaat tgtggagcaa cttaccataa aattttcaac
    47881 cctacaaaag ttgaagacac atgtgatcgt tgcggtgggc atgaattcta tcaaagagaa
    47941 gatgataaac ctgagacggt taaaaatcgt ctggctatca acatcaaaaa tagtgaacca
    48001 atcttggctt attataaaga acaaggtttg ctaaacacta ttgatggtgc tcgtgaaatc
    48061 gatgctgtat ttgcagatgt acaaaaaatc attgaaaaat agcacgattg cccgtagccg
    48121 acttgcatta tgcagttact cttgtcaagt tcaataaatt atgatagaat atgtcagtcc
    48181 gacttctaga gaatcctcta gatgatccat tttgagaatt ttgaggtggg aactgcagtt
    48241 tccgccattt tatcgtgtga aaatgcgaaa caagtacaag gaggtactgt gcgtggcaaa
    48301 agaagatatg attgaagtcg aaggtacagt cgtcgaaact ttgccgaatg caatgtttaa
    48361 agttgaacta gaaaacggac accaagttct tgctactgtt tcaggtaaaa ttcgtatgca
    48421 ttacatccgt atcttacctg gtgacaaagt aacggttgaa ttgtctccat acgatcttaa
    48481 ccgtggccgt attacttatc gctttaaata attgtactcc gtaaaactac aggaggtatt
    48541 atcatgaaag taagaccatc agtaaaacca atgtgcgaac attgtaaagt aattcgtcgt
    48601 aaaggacgcg ttatggtgat ttgcccagca aatccaaaac ataaacaacg tcaaggataa
    48661 ttggaggtgc tataaatatg gctcgtattg caggagtaga tattcctcgt gataaacgtg
    48721 tagtagtttc acttacttat atctatggta ttggtaacac tactgctaaa aagatcttag
    48781 ctgatgctgg tgtatctgaa gatgttcgcg ttcgtgaatt aacgaatgaa caaacagatg
    48841 ctatccgtgc agaagtagat aaattaaaag ttgaagggga tcttcgtcgt gaagtgaact
    48901 tgaacatcaa acgtttgatg gaaatcggtt cttaccgtgg aatccgtcat cgccgtggat
    48961 tgcctgttcg tggacaaaac acgaaaaaca atgcacgtac tcgtaaaggc ccagctcgcg
    49021 ctatcgctgg caagaaaaaa taattcttaa gtgaaggagg ttaaaacttc atggcagcaa
    49081 aaaaagtgaa tcgtaaacgc cgtgtgaaga agaatataga agcaggtatt gcacatatcc
    49141 attctacatt caataacact atcatcatga tcactgatac tcacggaaat gcattagcgt
    49201 ggtcatcagc tggttcatta ggtttcaaag gaagcaaaaa atcaactcct tttgccgctc
    49261 aaatggcagc agaaactgct acaaaagcag caatggaaca cggattaaag actgttgaag
    49321 taacagttaa aggacctggt tctggacgtg aagcagcaat tcgttcatta caagctacag
    49381 gtttagaagt gactgcaatt cgtgacgtga ctccagttcc tcataatggt gcccgccctc
    49441 caaaacgccg tcgtgtttaa tgagtgccgc tcattttgag ttttatcagt aacgtcattg
    49501 aacaagacac ttttcgtttt gaaaggggta aagataagaa tgattgagtt cgaaaaacca
    49561 agaatcgcaa aaattgatga agaaaaagat tatggcaagt tcatcgttga acctcttgaa
    49621 agagggtatg ggactacttt agggaattcc ctacgtcgta ttttattatc ttctttgcca
    49681 ggtgctgcca tcactaatat tcaaatcgat ggtgtactgc atgaattctc taccatcaaa
    49741 ggtgttagag aagacgtcac tcaaatcatc ttgaacatta aaggcttagc gctgaaaatg
    49801 tatggccaag aagaaaaaac ccttgaaatc gatattaccg gacctgctac agtaactgct
    49861 ggcgatatta tcgttgatag tgatgtagaa attcttaaca aagatatgta catctgtagt
    49921 gtctctgaag gagctacgtt ccatgctcgc ttaacagtga aacctggacg tggttatgtt
    49981 caagcagatg aaaataaaaa agaagatatg ccaattggcg ttcttccagt cgattcaatc
    50041 tacacacctg ttcgtcgtgt gaactatcaa gttgagaaca cacgtgttgg acaccgtgaa
    50101 gattttgata aattgacgat ggagatttgg acagatggtt caattgaacc gttggaagca
    50161 atgagtttgt ctgcgaaaat catgactgaa catttggata tttttgtgaa cttaactgat
    50221 gaagcaaaaa atgctgaaat catggtcgaa aaagaagaaa cacaaaaaga aaaaatgttg
    50281 gaaatgacga tcgaagagtt agacttgtct gttcgctctt acaattgttt gaaacgtgca
    50341 ggaatcaata ctgtacaaga acttacaaat aaatctgagc ctgaaatgat caaagtccgt
    50401 aacttaggac gtaaatcatt agaagaagtt aaagcaaaat tgcacgactt aggtttaggt
    50461 ttacgtaaag aagattaaaa ccttttacga aggagggaaa ccaacgtgag ttatcgtaaa
    50521 ctaggacgca catctagcca acgtaaagcg atgttgcgtg atttaacaac tgatttatta
    50581 atcaacgaac gtattgtgac tactgaagct cgtgcgaaag aagttcgctc aactgcagaa
    50641 aaaatgatca ctttaggtaa acgcggagat ttgcatgcac gtcgtcaagc tgcggctttc
    50701 gtacgtaatg aagttgccag cgtgcgtgaa gaaaatgagg acatcgtcat tgaatcagct
    50761 ttacaaaaac tgttcaacga tattgcacct cgttacgcag aacgtcaagg cggatacaca
    50821 cgcattttga agacagaacc aagacgcggt gatggtgcac caatggttgt cttagaactt
    50881 gtctaaaatc acactaataa catcacttta tagatgattc ttttagagtg ttatgatgtt
    50941 ggaagatatt tttccgagtc tagctcagcg ctgctcctca agcgaatatc gcttggggag
    51001 taagcactca tcataaagtg tttttttata ccttcaatta cctgtcatga cagatatgtt
    51061 tgaaggcata aaaaaacatt ttaagcgaga aataattgaa aattttgtct ttttttgata
    51121 gtgttagtag gaactttagg atgaagaagg agtaatcatg gagccaatta ttgaattaga
    51181 aaagataaat tataaatacc agccagatga tcttcgcccc gcattgaaag atgtctcctt
    51241 tacaattgat aaaggtgagt ggatcgctat tattggacac aatggttcag gaaaatcgac
    51301 acttgccaaa acgatcaatg gattgcttct gccagaatca gggatcgtga aagtgggaaa
    51361 tcaaatattg gatgaagaaa atatttggac gatccgacag atggttggaa tggtttttca
    51421 aaatccagac aatcagtttg ttggttcgac agtagaagat gacgttgctt ttggtcttga
    51481 aaatcaaggg attcccagag aagaaatgct agtgcgtgtg aaagatgcac ttgagaaagt
    51541 tagaatggct gagtttgctt cacgcgagcc tgctcgttta tcaggagggc aaaaacaacg
    51601 tgttgccatt gccggcgtgg ttgccttacg acctgatatc attattttag atgaagcaac
    51661 cagtatgcta gatccagaag gtcgtgaaga agtgatctct acgatcaaga agatcaaaga
    51721 agaaagtcaa ttgaccgtta tatctatcac tcatgatatt gatgaagcag ctaatgccaa
    51781 tcggatacta gtgatgagac aaggcgaact tgtccgtgaa ggtacaccaa aagaaatttt
    51841 ttctgctggt cctgaactga tcgacttagg tctagatcta ccatttcctg aaaaactgaa
    51901 gagcgcactg aaagaacgtg gggttgatgt gcccagtgaa tatatgacag aagaaaggat
    51961 ggtggattgg ttatggacat ccgttttgaa caagtagact tcacttatca gccgaataca
    52021 ccatttgaac aaagagcctt atttgacatc aatatgacga tcaaagaaaa cagttatact
    52081 gcattagtag ggcataccgg aagcgggaaa tcaaccttac ttcagcattt gaatgcgctt
    52141 gttaagccaa caagcggtac agtccatatt ggagaacgag atattcagcc ggatacggat
    52201 aataagaatt taaagcccat ccgaaaaaaa gttggcatcg tctttcagtt tccagaagca
    52261 cagctattcg aagaaacggt agcaaaagac attgctttcg gtcctaaaaa ctttggtgtc
    52321 agcgaagaag aagcactagt cctagcaaaa gaaacattag aacaagttgg gctggatgaa
    52381 agctatttgg aacgttcgcc atttgaactt tcaggagggc aaatgcgtag agtagcaatc
    52441 gctggtgtgc ttgccatgag gccggaagta cttgtattgg atgaaccaac ggcaggactt
    52501 gatccccagg gcagaaaaga aatgatggag atgttttggc gtcttcataa ggaacagcag
    52561 atcactattg tattagttac gcatttaatg gatgatgtag ccaattttgc agattatgtc
    52621 tatgtgttgg aaaagggacg aatcgttaat agcggggagc cgcaagaggt ctttcaaaac
    52681 attgaatggc taaaagaaaa acaactaggc gtacctactg ccaccgagtt tgcagaagaa
    52741 ttaatggcta aagggatgaa ctttgctacc ttgcctttga cagctgaaga attagcagac
    52801 gctatcgtcc attatgctgg aggaaatgcc catgatgaat aaattgatat ttggtcgtta
    52861 tatgcctgga gattccttga tccatcgatt ggatccccga gctaaattat tagccagttt
    52921 ttattttatc ggaatcattt ttttagcaaa taattgggaa acgtaccttt tgttggcatt
    52981 tttcacatta ctttctgtct tcttgtcaaa agtagatttg aaatttttta tccgaggcat
    53041 tcgcccattg atctggctaa tcctcttcac tgtagctttg caggtcttgt ttacaagtgg
    53101 cggagaaact tattggagtt ggggtgtttt ccatatcact gaatttggtg tgatgaacgg
    53161 cctctttatt ttctgtcgat tcgtgttgat catttttatg tcgactctac tcacgcttac
    53221 tacaccgcct ttggaattat cggatgcgat tgagtacttg cttcgtccat tgaaagccgt
    53281 acggttccca gtccacgaaa tttcattgat gctgtcgatt gctcttcgtt ttgtgcctac
    53341 attgatggac gaaacagaaa agatcatgaa cgctcagcgc gctcgcggtg ttgattttgg
    53401 tgaaggaaac ctagttcaga aaatgaaagc agtcattcct ttgctgattc ctttatttgt
    53461 cagcagcttc aaccgtgcgg aagatcttgc gactgctatg gaagcaagag gctacaaagg
    53521 tggggaagga agaacgaaat atcgtgtatt gcattggcat aatagagaca cgatggttat
    53581 cattgctttt gtattattaa ctgtgctact gatcttttta agaggataaa cgttcagtgg
    53641 gccgctatct attcttttct tgctgatctg tttgcaagaa aggatgcaag cagtgtatga
    53701 caagaaatat tagggtctgt ggcagactaa ggtcacaggc ctctttcttt tatctgaaaa
    53761 gaaagaacga aaaaat
//
LOCUS       DAZKCH010000007        51130 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000007 DAZKCH010000000
VERSION     DAZKCH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.007"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            290..1135
                     /locus_tag="ACG84X_000475"
     CDS             290..1135
                     /locus_tag="ACG84X_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9126382.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="ACG84X_000476"
     CDS             1416..2636
                     /locus_tag="ACG84X_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFP9126383.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="ACG84X_000477"
     CDS             2633..5353
                     /locus_tag="ACG84X_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9126384.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="ACG84X_000478"
     CDS             5337..6281
                     /locus_tag="ACG84X_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFP9126385.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6350..7360)
                     /locus_tag="ACG84X_000479"
     CDS             complement(6350..7360)
                     /locus_tag="ACG84X_000479"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9126386.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7540..7884)
                     /locus_tag="ACG84X_000480"
     CDS             complement(7540..7884)
                     /locus_tag="ACG84X_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFP9126387.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7877..8311)
                     /locus_tag="ACG84X_000481"
     CDS             complement(7877..8311)
                     /locus_tag="ACG84X_000481"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFP9126388.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8449..9186
                     /locus_tag="ACG84X_000482"
     CDS             8449..9186
                     /locus_tag="ACG84X_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126389.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9179..10390
                     /locus_tag="ACG84X_000483"
     CDS             9179..10390
                     /locus_tag="ACG84X_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126390.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10594..11376
                     /locus_tag="ACG84X_000484"
     CDS             10594..11376
                     /locus_tag="ACG84X_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFP9126391.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11446..12108
                     /gene="trmB"
                     /locus_tag="ACG84X_000485"
     CDS             11446..12108
                     /gene="trmB"
                     /locus_tag="ACG84X_000485"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFP9126392.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACG84X_000486"
     CDS             complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACG84X_000486"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFP9126393.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14092..15021
                     /gene="comGA"
                     /locus_tag="ACG84X_000487"
     CDS             14092..15021
                     /gene="comGA"
                     /locus_tag="ACG84X_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFP9126394.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14978..16027
                     /gene="comGB"
                     /locus_tag="ACG84X_000488"
     CDS             14978..16027
                     /gene="comGB"
                     /locus_tag="ACG84X_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFP9126395.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16024..16302
                     /gene="comGC"
                     /locus_tag="ACG84X_000489"
     CDS             16024..16302
                     /gene="comGC"
                     /locus_tag="ACG84X_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFP9126396.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16277..16747
                     /gene="comGD"
                     /locus_tag="ACG84X_000490"
     CDS             16277..16747
                     /gene="comGD"
                     /locus_tag="ACG84X_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFP9126397.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16719..17066
                     /locus_tag="ACG84X_000491"
     CDS             16719..17066
                     /locus_tag="ACG84X_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126398.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17029..17454
                     /gene="comGF"
                     /locus_tag="ACG84X_000492"
     CDS             17029..17454
                     /gene="comGF"
                     /locus_tag="ACG84X_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFP9126399.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17426..17785
                     /gene="comGG"
                     /locus_tag="ACG84X_000493"
     CDS             17426..17785
                     /gene="comGG"
                     /locus_tag="ACG84X_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFP9126400.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17957..18964
                     /locus_tag="ACG84X_000494"
     CDS             17957..18964
                     /locus_tag="ACG84X_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9126401.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18989..20173
                     /locus_tag="ACG84X_000495"
     CDS             18989..20173
                     /locus_tag="ACG84X_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFP9126402.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACG84X_000496"
     CDS             complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACG84X_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFP9126403.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22298..22426)
                     /locus_tag="ACG84X_000497"
     CDS             complement(22298..22426)
                     /locus_tag="ACG84X_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126404.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22771..22914)
                     /locus_tag="ACG84X_000498"
     CDS             complement(22771..22914)
                     /locus_tag="ACG84X_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFP9126405.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23137..23616)
                     /locus_tag="ACG84X_000499"
     CDS             complement(23137..23616)
                     /locus_tag="ACG84X_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFP9126406.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23689..23973)
                     /locus_tag="ACG84X_000500"
     CDS             complement(23689..23973)
                     /locus_tag="ACG84X_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126407.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24051..24245)
                     /gene="ssrS"
                     /locus_tag="ACG84X_000501"
     ncRNA           complement(24051..24245)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACG84X_000501"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24317..25603)
                     /locus_tag="ACG84X_000502"
     CDS             complement(24317..25603)
                     /locus_tag="ACG84X_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFP9126408.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25741..26412
                     /locus_tag="ACG84X_000503"
     CDS             25741..26412
                     /locus_tag="ACG84X_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFP9126409.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26378..26866
                     /locus_tag="ACG84X_000504"
     CDS             26378..26866
                     /locus_tag="ACG84X_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFP9126410.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26879..27826
                     /gene="prmA"
                     /locus_tag="ACG84X_000505"
     CDS             26879..27826
                     /gene="prmA"
                     /locus_tag="ACG84X_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFP9126411.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27827..28591
                     /locus_tag="ACG84X_000506"
     CDS             27827..28591
                     /locus_tag="ACG84X_000506"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFP9126412.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28824..31037
                     /locus_tag="ACG84X_000507"
     CDS             28824..31037
                     /locus_tag="ACG84X_000507"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFP9126413.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31048..31494
                     /gene="dtd"
                     /locus_tag="ACG84X_000508"
     CDS             31048..31494
                     /gene="dtd"
                     /locus_tag="ACG84X_000508"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFP9126414.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31665..32924
                     /locus_tag="ACG84X_000509"
     CDS             31665..32924
                     /locus_tag="ACG84X_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFP9126415.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33013..33960)
                     /locus_tag="ACG84X_000510"
     CDS             complement(33013..33960)
                     /locus_tag="ACG84X_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFP9126416.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34354..35646
                     /gene="hisS"
                     /locus_tag="ACG84X_000511"
     CDS             34354..35646
                     /gene="hisS"
                     /locus_tag="ACG84X_000511"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFP9126417.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35661..37430
                     /gene="aspS"
                     /locus_tag="ACG84X_000512"
     CDS             35661..37430
                     /gene="aspS"
                     /locus_tag="ACG84X_000512"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFP9126418.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37539..38414
                     /locus_tag="ACG84X_000513"
     CDS             37539..38414
                     /locus_tag="ACG84X_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9126419.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38680..40563
                     /locus_tag="ACG84X_000514"
     CDS             38680..40563
                     /locus_tag="ACG84X_000514"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFP9126420.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40638..40922)
                     /locus_tag="ACG84X_000515"
     CDS             complement(40638..40922)
                     /locus_tag="ACG84X_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFP9126421.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40912..41646)
                     /locus_tag="ACG84X_000516"
     CDS             complement(40912..41646)
                     /locus_tag="ACG84X_000516"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFP9126422.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41775..42398
                     /locus_tag="ACG84X_000517"
     CDS             41775..42398
                     /locus_tag="ACG84X_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFP9126423.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42590..43711
                     /locus_tag="ACG84X_000518"
     CDS             42590..43711
                     /locus_tag="ACG84X_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFP9126424.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43718..46846
                     /locus_tag="ACG84X_000519"
     CDS             43718..46846
                     /locus_tag="ACG84X_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9126425.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46865..50059
                     /locus_tag="ACG84X_000520"
     CDS             46865..50059
                     /locus_tag="ACG84X_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFP9126426.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50205..50912)
                     /locus_tag="ACG84X_000521"
     CDS             complement(50205..50912)
                     /locus_tag="ACG84X_000521"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9126427.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16731 a         8938 c        10624 g        14837 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 tcgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt tattttgatg
     6361 aatcagttgt ttcttcagtt gaagattctt ttgttgaatc agttgatttt gtgtcagaac
     6421 tctttgttga agctgtagtt tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg
     6481 cactcaacac attttcaaag gcatcatctt tgatttttac atttgcatct tttaattctt
     6541 caccgattac tttagttgtg aatgcattgt cacttagttt agtttcagta gcgatatctt
     6601 ttagttgatc tttgtattta tccatgtcat tgcctttatt ttggtttttc accattttga
     6661 caacgtagta ttctgtcgca taagaagtag gatttgttgt agtaataaca tcggagatct
     6721 caccgtcttt caatttgaaa gctgcttctt ttacttctgc aggaatagtt gttgtcgttg
     6781 agtcgaattt aactttaccg ccatcttctt ttgtctctgt atcagttgat ttgtctttgg
     6841 ctaatttaga gaaatcatct ccatcatccg ctgatttttt cacatctttt gcttcatctt
     6901 cacttgataa tttgatgatt tgtgcttcta cttctggatg gaaagatttc caagcagttt
     6961 tcaaatcgtc atctgtaata tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt
     7021 tacgaatata ttctttataa gtatctttcg tatatccagc agcttctaat tgtgattcaa
     7081 aagtatcacc taatgatttc gcttgtttgt cgtattctgc atccacttgc ttatcggtta
     7141 ctttatcgcc atatttgtta ttgaatactt tataaatgat catccgttgt actaaggatt
     7201 ggttcgatga ttcaagtttt gcttcatcat agaaatcaga tacagtgatc gttccgcctt
     7261 tcatcgttgc gatatcttta ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca
     7321 acgcactagt agctgccaaa ataattgatt tttttttcat taaaatttgc actcctgtaa
     7381 ttagttatta tttttatata ttaactatac catatcccat ttcctttaaa aacgttgtcg
     7441 tggtagtttc aaacaaaatt caaaatttca tcacattcct aggaaatacg caaacttttc
     7501 tcacttatat agttaaatct gttgagaaaa taatcattat tatatttgtt caggatactc
     7561 tggcagatca gcttttagtt tttctacttg ttcattgatt tgtgtgatac gtggttcggc
     7621 ttggaattta aaatcttcga tatctttttt gattgcttct tggaaagcag gaatcacaga
     7681 ttcagctgtt tcttttgttt cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa
     7741 atcatttgtc agagttgttg cttcttccaa ttcttcgatc agtttctttc ttgtttcatt
     7801 cccgctcctg ggcgccaata acagacctcc gacagtgcca gcagcagctc caaataacag
     7861 tcctttgaaa aagtttttaa tcatcgcagg acacctgctt tacgattgtt tcttgaatag
     7921 cttttagttc ttccgatcca taactatctt gatgattgac aaagtgaata gaaaaatcat
     7981 cctctttgct gtagcgaggg actaaatgga tatgtgaatg aaaaacagat tgataggcta
     8041 gttcacggtt gttattcaag atattaagac ctttcatttc tggaaaagct ttttccaatg
     8101 cttgagcaat cttaggcaca cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa
     8161 aaatatctgc tacatgacgt ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga
     8221 tgtctaaaaa agcatagacc ttgtcgtctt catatatttt atagcttggg atttcttgat
     8281 tgatgatttt gcaaaaaata cagttttcca tataaaacat cctttctata aagaataaat
     8341 acttcagctt aactttacca taagttaaag ctattgtaag gaaaaaaaca aaataccgtc
     8401 attttcttcg tggtataata aataaaaata aatggcggag gaaaaagaat gagtttaatt
     8461 atcgatcatg tcacaggggg gtacggacat ctccctgtgt taaaagatat cagtttcgat
     8521 gtacagcctg gagagatagt agggttgatt ggactgaacg gagcagggaa aagtacgacc
     8581 atcaagcaca ttatcggtct gctggaagct tcaaaaggaa cgatagaaat caatcatcta
     8641 tccttaaaga aaaatacgga agaatatcgc aaacaaattg ggtatattcc agagactcct
     8701 tctttatatg aagaattgac attgagagaa catatcgaag tcactgcgat ggcctacgat
     8761 atacctatgg atatagcaat gaaaagagca gaaaagttgt tggagacttt tcggttatct
     8821 aatcgtcttg actggttccc agctaatttt tcaaagggaa tgaaacagaa agtgatgatc
     8881 ttatgcgcct ttttgatcga gccttcttta tatatcatcg acgaaccatt tttaggcttg
     8941 gatccactag ctatcaatgc attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc
     9001 ggtattttga tgtctacgca tattttagct actgcagaaa aatattgtga tcgttttgtg
     9061 gtcttacata acggagagat acgagcagac ggttctcttg agatgttgag aaaagaattt
     9121 cagctgccgg attcttcttt ggacgaaatc tatattgctt taacaaagga gcaggcacat
     9181 gagtagtttt tttcaaaaac gtttagcaag acatcaaaag aaaatgatga aatatatgcg
     9241 ttatgtattg aacgatcatt ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt
     9301 atattattct aattggttga aaaccctgca gccaccgttt gcaattggag ggctcataat
     9361 ctctgtattt tggatgctct gtttattcgt gggtaagatg gctacttttg cagaggcagc
     9421 agatattgtt tttttacttc ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt
     9481 tcgctattct tgcatttttc cgttgatctt tttgatattg gcatgcggat tggccatgcc
     9541 attagtggtg gttagtacgg agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt
     9601 atggagtttg aaattcagtc atctgcaaat caagagagca gaattgtttc gactagatca
     9661 acaagttatt cgttattgga aattaggctg gtttttttct tctctgatct ttttgtttct
     9721 atcattttat tggctaatat gggcaggaat agcaggtgca ttagtacagg caagtctata
     9781 ttactggttt ttgtggaagc aacaagaaaa aggattggat tgggagaaaa tggtgcatgt
     9841 agaagaacat aggttgcatc agatctatca atttatcaat ttattcacag atgttcctga
     9901 aattacggca aagatcaaaa gaagacgcta tttggatcct atattgactc atattaaaag
     9961 agaatcaaaa aacacttatc tttacttgtt tgcaagaaga ttggcaagag gttctgattt
    10021 tagtggtctt tatttccgat tagtaattat aggtgggtta ttgattgccg gagtagtcga
    10081 cttttatttt agtctgatta tcggtttctt atttttatat ttgatcggtt tccaactgtt
    10141 acctttagcg aaccagttcc gctatatggt tctcgttcag ctttatccaa tccataagaa
    10201 tcagaagaag caggcgattc agtatctact cacatgggta ttaattatcg cgtcggttat
    10261 ttttggtttg attgctgcag tcgtattaga tgggcagcag cgatgggttc cgctagcggc
    10321 ttatttgatt gttactatgc tctttgttaa actatatgta ccaactcgtt tgaagaagat
    10381 gtcagactga aaacaaagct gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca
    10441 gtaagaatgc tgttcgttct attttttttg agaaaagctg gttttttgaa tggcaattaa
    10501 atgaaaaaga acgtatatgt gcttgacgtg tagtgttcag gcgactagaa taataagtac
    10561 tgcaaaacaa agagtaagag gacgggagaa tgcatgatgg agtttcagtt agaccaagag
    10621 tggcggttac gtcccatcaa aggcgacaca ggaaaaacat acataggcat gcgtgatgag
    10681 gacaaagtct ttattaaacg aaacacgact ccgatgttgg ctgctctttc aagggaagga
    10741 attacaccaa aacttgtttg gacaaaacga acggggaatg gcgatacttt gacagcacaa
    10801 gagtggctgg aaggtcgctt gctgactcct aatgagattg gtcaaagaaa cgacgtgatt
    10861 gatgttttgt accatttaca tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt
    10921 ggtcgtgtca tgacgccgga gaagatgctg caaaaatatg aaaaagaatt accggaagaa
    10981 ctccagaaaa atcaatttct gcaaattgtc catcgttttc ttcgtgagca gatcccgtca
    11041 atagataagg aaaacttatc agtagtacac ggagatgtaa accatcgtaa ttggttagta
    11101 tgtaaaaatt atttatatct agtcgattgg gattcaatca tgtttgcaga ccctgcggtg
    11161 gatattgcaa cgattttagg aaattatgtg ccactgtcta gctggaatca gtggctgatc
    11221 agttatggca tacgcccgac tgacgaaatg cttgaaaaat ttcattggta tgcggccatg
    11281 aatttgctcc aagaaatcac cagatattgc aaacgtgaag atcatcgacg gatgaacgaa
    11341 gaaattttac aattaaaacg aattttcagt ggctgaggtt tggcccaaac tctgcggaga
    11401 tttggccaga cctttttaat tagaggaaag gaatggagat aaataatgcg tgtccgaaat
    11461 cgtccgggag cagcggaaat gttagcggct cacccgaatt ttgtaattag tgatccaaca
    11521 ttgtggaagg gaaaatggaa tgaattgttt gaaaacgatc atccaatcca cattgagatt
    11581 ggtatgggga aaggccagtt catcactgga atggcaaaag cccatcctga aatcaattat
    11641 attggagtag aaatgcaggt cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa
    11701 ccgcttccta acctgaaact tctacatgtg gatggatcag cgttgacaga gtatttcgct
    11761 gacagcgaag tagatcaaat ctatctgaat ttttccgatc catggccaaa aaaacgtcat
    11821 gaaaaacggc gattgacata taagactttt cttgctgtag atgaacagat tcttcgtcca
    11881 aatggagaaa tccatttcaa aacagataat caaggattgt ttgagtattc tctggcaagt
    11941 ttttctcaat atggcatgat cctcaaacag gtatggttag atttacatca aagtcaattt
    12001 gaaggcaata ttatgacgga gtatgaagaa aaattttctt caaaaggtca acgtatttat
    12061 cgagtagaag ctcaatttca agataagacc aaaaagaaaa gtctgtgaaa ctaactttct
    12121 gctttcataa aaacattaat atccataaat aaatcccaga aaatgaacat tacagatgta
    12181 atgtattttc tgggatttat ttgatttaaa atgtatttat ttcatcggtt tttccacaag
    12241 gtggaatcaa ttggaagcga gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg
    12301 gtatgacaga taatgttaag aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc
    12361 ctagttgatg tgctttagtt attaattcat tcaactgttc atagacgatc gaaaaaggtt
    12421 cctgtgtcat gattccgcct ataggaagag aaacacaagc tatttcctgc tgtttgttga
    12481 caacggtcat cccgccacct ttttgaatca aaagattagc agcatacagc atatcctcgt
    12541 cgtttgtccc aacgacaact agattatgcg agtcatgggc aatcgttgtc gctatcgctc
    12601 cttgtttcag ctgaaatcct ttcactatgc ctaatccaat gtttcccgtt tgatggtgac
    12661 gctcgatcac cgcaatcttt aattggtctt tttcgattga aggaatgaat cgttcgcctt
    12721 gtcggtccac tttttctacc aaatctttag tcactagact attcgggata atttcgatca
    12781 catgggcttg tgaagaagaa agaagcagct ctaacgaatg tggatttaat ggttgagcgt
    12841 ttagttttgg cagacaacac gtatatgaat ttgaatgatc agcaaataaa tggtcttgga
    12901 gttgcccaga ttgaacaact aatgttccct tatagaaaac ttcatgaatt ggcagcttgg
    12961 taagatcgtc tgttaagaag aaatcagctt gatacccagg ggcaatcgca cctagtgttt
    13021 tcaaatcaaa acattctgct gcattcaatg ttgccatctg aatggcttgt aatggatcga
    13081 ttccaagtgc aatagcttga cggacgatat gatcgattga tccttctttt actaaatcat
    13141 tgatcagttt atcatcggtg acaaagaagc atcttcttga attttcaggt gtgatcgccg
    13201 gtagtagcga tgccagatct tttgcaacgg tcccttctcg aaccattaaa tacataccaa
    13261 gatccaaacg ttctttagct tcttttgcag ttgtagcttc atgatccgtc cgaatacctg
    13321 ctgcaggata aacatttaac tcttccatgc cgataccagc tgcatgcccg tcaatttttt
    13381 tcttatgctg gtgcatcaat tggatctttt ctaggatgtc tgtttcatta tttgctactg
    13441 cttgatagtt catgacttca gctaagccta aaacttcggg tttttgtaaa aaaggggcta
    13501 atttttttgc atttaaattt gcaccattgg tctcaaaagg ggttacaggt acacaagaag
    13561 gtagcataaa aaagatattc atgagtgttt gtcttgcatc ttctatcata aactcaagac
    13621 ctgtactccc agcaatgttt cctatttcat ggggatctgt cactacagta gtaactccat
    13681 gaagcaagga tacttttgaa aattcgcttg gtgataaaag tgagctttcg atatgcacat
    13741 ggccatcgat gaatcctggc actagatatt gcccattagc attatgtacg ctttttcctt
    13801 cgtattcacc gattcctacg atcattcctt cgcagattgc tacatctttt tccatgattt
    13861 ctttcgtaaa gacgttgacg atcttagcat gcttgatcac taggtcagca ggcttttttt
    13921 tacttgctac ttcgatatat ttccttaatg ttgtttccaa tggagtgcct cccaagataa
    13981 atttttataa gtataacata aattcggttt ttgccaatat ttttttgtaa attcatttta
    14041 tttgaaacaa aaagatcaaa aagacgtatg ttttttgtgg aggggagaat aatggaaata
    14101 aaacgattat cggatcaaat gataagtgaa agttttgcca aacatgccca agacgtatat
    14161 atattgccag cttcagaagt attttacatc tattttcgct atggaaaaaa acgaacattc
    14221 tggaagaaag tctcttcggc agatggacag caactgatct caagatttaa gtatttggga
    14281 cagatggata tcggagaaaa aagaaaagct cagttaggtg catttactta ttctttagaa
    14341 aaacaggaag ttcgtctgcg gttgtcttct gtaggagatt accttcaacg agagagttta
    14401 gtgattcggc tattatacgg tacttttgaa acaccccatc gttgctttag ttctcgagat
    14461 tttgcaacta ttttacagaa aaccgtcaga cgtggattat accttttcag cggaccagtc
    14521 ggatcaggca agacttctct aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt
    14581 actatcgaag atcctgtaga gatagaagaa ccgttttttc tgcagctaca gatcaatccg
    14641 aaaatagcac agacttatga tacacttttg agactcgcat tacggcatcg tccagacttg
    14701 ctaatcattg gcgagataag agatgaatca actgcacatg ctgcggtaag agcagcacta
    14761 acagggcacc gggtttttgc aaccgtacat gcacgcaatc ttgaaggtac attggtcaga
    14821 atccatgaac tgacaaagaa aaaagaagag ctatctgaat gtttagctgg tgtcatttat
    14881 caagaacttt tggaagatgc caatcaccat ccttctgttt tatggagtta tcaatttatg
    14941 gaggaagaat cagtaaaaaa atcatgggag gaaagttatg aagaagctca ggaaaatatt
    15001 tggcagtcag aactattcta aaggattaac aagaagccag caaaaccagt ttgcacaaac
    15061 catgggagaa ctgcttttat ctggttttag tctgcaagaa tccctttatt tattactcac
    15121 gatccgttcg tttccacctg ttattttggc aaatatccaa catcagctaa aggaagggca
    15181 agcgtttagt gaggtacttt cgcaaatagg atatggagca gagcaactgg tacagatcga
    15241 gttagctgaa cgtcatggga atctgccgac aactttgttg gaaattgcca aacagtttcg
    15301 gcttgttgaa ggatttcgca atgatttgaa aaagctgctt gcatatccga tgctattgct
    15361 cacctttttg ctaggtatct tgtttagtat gcggttgttc gttttgcctc agcttattgg
    15421 ttcaggaatg gtcatgcaag agcattgggg tattcagctg atacaagtct ttcattggta
    15481 tgttctacta ttcatcctag cggttactct attggcttta ctagtaaggt atcgtctgat
    15541 gaagttgtct cctgttgatc agagtgaatg gataagcaga caattattga ttggaccgat
    15601 atattccttg tatcaatcgg cttatttgtc actagagatt ggaaagcttt ttcatgaagg
    15661 tttcgaatta aggcaaatca tagtctgctt aaaggaaacg aaacaagaaa gtctgattca
    15721 gcatcttgcc tctaagttga ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt
    15781 ccagaattat cgttttctat cagaagaatt cagtaaaatt gttttacagg gagaggcaaa
    15841 gggaagttta ggtaaagaac tgatttttta cagcgaatgg acaagaaaac agcttttcaa
    15901 acgtcttcat cactggatgc attttattca gccaatcatt tttttgggcg tagcggcttt
    15961 gattttatta gtttatgccg ctgttttatt acctgtttac ggaagcatag aggaggtttt
    16021 gccatgaaaa agagaaaaat atcttattat agcggtttta cattgatcga aatgctaatc
    16081 gtcttactga tcatcagtgt attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg
    16141 aatcatgtag accaagaaag tcgtgaagcg atcatccagt tggtagacac acaaaaagag
    16201 ctctatgcgc ttcaaaataa tggaagagtt cctactgtgg aggaattgtt gaatgaaggc
    16261 tatatcaaac gagaacatgc agaaatctat cagcggcctt gaaggtaagg ttttagcatc
    16321 aggatatacg ttgtttgaat cactcttact gattttatta cttacaacga tcctttcttt
    16381 tccagttctc gcattttctg catggaagaa tgaattggca gtctatcaat ttttcggcca
    16441 atttgaaaaa cgaatctatt ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg
    16501 cttttattgg aatagtgaag agaatcaaat catttttcat gttccgaatc cagataaaat
    16561 aaattgggaa gtattagata ttcctgatga gattaccttg aaacgccatg cttctattac
    16621 ttttgctgct agaaccggga atgaaagttc actaaaagct tatcaatttt attgggaaga
    16681 aaaagagcgg acgattacgt atcaattcca gatagggagt ggtcgctata caaaaagaat
    16741 tgaataaaac aggatttgtt ttgttggagt cccttacagc gcttatgatc gcttctgtct
    16801 gtgtctactt agtgagcttt ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg
    16861 aggaactgct atttattcga atgatttatg aagatatcaa gacgcagcgg atgtatcaca
    16921 aaagaccaga gcgaagggaa gaaatgatcc catacgatat ccaaattgtc gataataatg
    16981 gagtaatcga aaaagtgttt gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa
    17041 gtaattccag catttacgct gattgaatgt ctaattggac tgatgatatt gagcagtcta
    17101 ttgctcacat tcaatctttt gattcagcaa accatccaag taagtgaatt tttgcagcgt
    17161 aaagatcaaa aagagtggct aatattttta gcacaattag aagaagaact caagagcagt
    17221 cacaatgtct ctgtgaaaaa tcagcaactg cactacacga tcgaggataa acagtatatc
    17281 atcgaaagat atcaggcaat gatacgtaaa agaagaactt ccggcggaca tcaacctatg
    17341 ttaacaagta tcactgagct tcaattattg gaaaaagaac acacaatttc tttttatgta
    17401 cactttgaaa atggagaaga tggatatgcc atatggacaa aaaacgatca gtagaaaatg
    17461 ttataagggc tctattttat tttctgtctt gcttttattt cttttatgta cgtttttatt
    17521 gatggcagca ttagaaagct accgtttgtc aatggatctt aatatacgaa tcaaaaatta
    17581 ttatatagca aaaataatga agcagatggc tttatcggaa cagtctacgc ttgccgaaag
    17641 ttcggaagga gttttttact acacaactgg atctgtaaca tatcagtggg tacaacagtc
    17701 cctattctta gaggtggaag tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa
    17761 tgatacagat actagtacag aatgatggaa tgttcgtgaa aacgccctct tttctgttat
    17821 aacactgttt ttaataaaaa aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat
    17881 tgaaattttg tcaattgttc gatagaatta aacaggtgaa aaaattgtta taatatatct
    17941 agaaatgagg tgcaccatgt taccagaaaa aatggaacaa gggtttaatc aaaacctgga
    18001 agctattcag cttttacaga atgcattggg aacttccttt ttagaagcct atgtcgaaaa
    18061 tgcagaaaat ttaatagatg attatcaagt acgtgtggtg gatggagtgc cgacaaaaga
    18121 gacaacgcaa cggatcacag ctctttatga agagttgaag aaactttctt tcgagccaga
    18181 agaatggcgc agactgtctc aattactttt attgaagggc agccagacag aacatttgca
    18241 ggcgaaccat caactcactc ctgatagtat cggtttttta tttgtttttc ttattgaaca
    18301 actatacaca aataaaaaag caccggttaa gattctggat attgcggcag gaatgggcaa
    18361 cttgttatta acagttcttt taaacctatc gaatgcgggg taccaaacag aaggaattgg
    18421 tgtggatatt gatgatacat tgttggctgt cgcagcttct acaagtgatt tgacacaagc
    18481 aaatgttcaa tactttcatc aagacgggtt gcaggaatta ttaatagatc ctgtcgattt
    18541 tgcaatcagc gatttgccaa tcggttatta tccgaatgac gaaaaagcaa aagagttttt
    18601 aacaagtacc gaagaaggcc atagttatgc acatcattta ttgctagagc aatcaatgaa
    18661 atatgtgaag ccggatggtt ttggtttgtt tttgatgccg agtggatttt tagaaacgga
    18721 tcaaagtgaa gaaatcaaaa aatggtttaa agaagaaggt tatcttcaag gaatgattca
    18781 attgccagat gaattgttcc gtaataaaca atcgcaaaaa agtattttga tcttacagaa
    18841 aaaaggacca caagcacaac aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa
    18901 agaaccagag aaggtgacgg aatttttcaa cgagtttaaa aactggaaat catctgctct
    18961 gtaatcattc aacgagaagg agagtcatat gtctaaaaca attgcaatca atgctgggag
    19021 ttcaagtttg aaatggcaat tatatcaaat gccagaagaa accgtagttg cgaaagggat
    19081 cgtcgaacgt atcggtttac aagattctat ttttaccatc aagtacggcg ataatcaaaa
    19141 attcgaacaa atcatggata tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca
    19201 gttgattgaa ctgcaaattt taagctctta tgatgaaatc accggagtag ggcaccgtgt
    19261 tgttcacgga ggagaaactt atggggattc agtagtgatc gatgagaaag taatggaccg
    19321 cattgctgaa ttagcagaat ttgctccttt gcataatcct gcaaacttaa tggggatcaa
    19381 agcgtttaaa aagattttac ctgacatttt gagtgtggct gtattcgata catctttcca
    19441 ctcaacaatg ccaaagcaaa attatttata tagcttaccg gtgtcttatt atgaagattt
    19501 caaagtaaga aaatatggct tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc
    19561 aaaattattg aacaaaccga tcgaagaact aaaaatcatc acttgccact taggaaatgg
    19621 tgtatcgatc acagcagtcg atggaggtaa atccatggat acttctatgg gattcacacc
    19681 attagctggg gtgacaatgg gtacacgttc aggtgatatc gatccagctg ttctcccata
    19741 tttaatggaa aaattagaga ttgatattga tgaaatgatc aatgttttga acaagaaatc
    19801 tggtctgcta ggcctaacag gattgtctag tgatatgcgt gatcttgaaa agaactatga
    19861 aaaagaacat attcgtttag cttatgacat tttcgtggac cgcatccgaa aatacatcgg
    19921 cggttatgtg acaacgatga atggtgttga tgcaattgtc tttactgctg gtatcggcga
    19981 gaatgacgga catgtacgta gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat
    20041 cgatccagcg ttgaatgaat tgcgtggtga agaagtagat atctctacaa aagaatcaaa
    20101 agtaagagta ttagtgatcc caacagatga ggaactaatg attgcccgtg atgtggagcg
    20161 tctgcgcggc taagccaaag cattcgttag gataaaagat gaaacgcatg caagagggaa
    20221 ttcttgcatg tgtttttttt gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc
    20281 cttctttttt acaggatctt cttagggaat tttgcttgga aaagtggtca aaagggaaaa
    20341 gactggcatt ttatttattg attttcagga aaatcccaat attttatttt cattcatctt
    20401 tataagggac attacatatg taaaaagaaa aaacattttt agatcagcct cgtgggctgt
    20461 cgactttatt cttcgcttta tgtttagcta gaaaaccgat ccgaaacatt cattgatcga
    20521 ataataaaaa cttgattttc cacctgtact ttgcctgaat cgtgaaagca caggtatgaa
    20581 aatcaagttt tttgttgcga aaaaacgtcc tagtcaatca gttggccgag cggctggcgg
    20641 ctgatctgct cctgatcaat aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg
    20701 tcatggctga ctgctaggag cgttccttga tagtcttgca gcatttcttc aatttcttct
    20761 cgagcatagc tgtcgaggtg attggttggt tcatccaaaa tcaggacgtt gattttttct
    20821 aaaaagagtt tcagcaacgc caaacggatt ttttcaccac cggataaatc tttgatccgt
    20881 ttacccacat cgctttgata aaagccactt ttggctaatt gccgtcgagc gacttcttcg
    20941 tttccagtca atgtgatggc gtaagccagc aaacggctat cgggatcggc aaactgcagc
    21001 tgctgcggca aataaccgat ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc
    21061 ttttcctcac cgagtaataa tttgagtaag gttgattttc ctgcaccatt gtcgccgatg
    21121 atggctaaat gatctccacg atagactgca aaactgctgt ctttgaatag tacttgatca
    21181 gcgtactgct ggtgcaagtt ttgaatgatg aaaacttctt tgccagattt tccaccatta
    21241 gacaagcttt gcagccgatt tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc
    21301 aggcggcgtt ccagttcttt ggcttttttg aagaaggact cattgtctcc ttcatgtgcc
    21361 cactgacgaa aacgacgaat catgactttc aaccgctgga cttctttttg ctgcagttcg
    21421 taattttttg tcagctcagc caagcgagct tctttcaaga ctcgaaaacg gctgtagttt
    21481 ccgggatact caatcaatgc accttcttcc agttcccatg tttttgtggt gacttgatcg
    21541 agaaattgcc gatcatgaga aacgaccaga accgattttt ttgtattctg taaatagttt
    21601 tccaaccagc gaatactgtt aagatctaaa tgattggtcg gttcatcgag taaaagtaaa
    21661 tcggcatcgg ctgctaaaat tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt
    21721 tctgttaacc gtgcttcctg acggtgtgga atccctaagc cttgcaagat cgctgcaatc
    21781 cggtcttcta atacgtaacc gcctagttct tcaaagcgat gctgcagctc accgtaacgg
    21841 gccagacact tctctaagtt tgtatctggt tctgtcatca atgcttcgta gcgactcatt
    21901 tgctgtttga ggtcctgtat ctcagcggca gaatggagca agtagtggtt gacggtcgct
    21961 tcggaaactg taagttcttg ttcgaccgtc ccgatcttta agcctttttt gcgactgata
    22021 acaccgctgt cgacaccttc tctgccggtc aagatttgta aaaaggttga tttgccagtt
    22081 ccgttgatac cgactaaggc aattttttca ccagcttcaa tttgacagga taaatcctca
    22141 aataatggat tcccgccgat tgttttttta atagaaattg cttgtatgat catgatctct
    22201 ctccttgaga ccactcaaaa aggccatggt tatccatggc ctgtgttatt taaactcaga
    22261 ttatcatgag aaaaatacct tgagatggcc attgatttta cgtgaattca actgttttgg
    22321 acaaacttgt cccgtcaaca gcaactgtaa aaccaattgc atggctaaat gcgatatggt
    22381 atcgttggta attttcatta cttgttattt tagtcatgcg catcatagta ttttccctcc
    22441 ttcgtgtagt tgtcttttcc agtgtacctg aaagtgtcag aaagttcaac tagcgctgac
    22501 atttacttaa tatttatcga tgtgtaattc tgtcagagag ctttttttat ctgactgagg
    22561 gtaatgtctc gtggaccaca tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca
    22621 tatggtgttt gataaaaaac tttgtctaca tgacttcctt ttgccatttg cttaataccg
    22681 ttgcattaaa cagctcttct ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt
    22741 gtggttgcaa tggcaagcgg tagcctttca tcaattcttg aatgatttac cgaatgtagc
    22801 acttgccttc tcgcggtacc cgaacccgaa ataaaatttt agtttggcga taaaatcggt
    22861 atccgccatc gatacttcat attttttcgt atcagattca tcggaaactt ccacattgac
    22921 gaaccaataa gctttggcat gcttaggtcg ttttaaacca caccagggcg actaatcgcc
    22981 ctggtgttca ctttttttta ttttacttga actcattgac tgttttccct ttattttaaa
    23041 cattataaag accgatgagt gcttgccgcg tcttttgttt ttatcacggt tttttgtgca
    23101 aaaaaacctg ccgatagttg gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc
    23161 tggcaattgg ttttctaaat cagttcggac aacaagcaca tcgcaagctg cgtttctaat
    23221 aacatattca gaaacagaac caataaataa acgttctaca gcattcaatc ctgtggctcc
    23281 taacataatc aaatctactt gattatcttc tgggatttct ctggcaataa tttgttttgg
    23341 tgagccatat tctacgacag aggttacatt attcaagcca gctttcttcg cattgctttc
    23401 ataatctgcc aatgtttgct ttgccatttc agtagcttgt tctgcaagca ttccatcaaa
    23461 ggatgaaacg gtttggaaag aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt
    23521 atttcggata gctacattga ccgccttttt aaaagctaat tcagcttcat cagaaccatc
    23581 tacggcaacc atgatttttt tgtattgttg taacataagc attcactcct caagtcaatc
    23641 gtattgtact cttttattgt agaacacttt agggaaaaag agaattattt actgctttgg
    23701 ttcagcaatt ttttttgcaa atcggatact gaaggtggca gaaacaataa ttacgatcag
    23761 taaaaagacc aaggcaataa agcgttgatt gaaaaaagct gttaaaatac ccattacgcc
    23821 taaaacagca tatgcagctc cgtaaaattg taggaatcct tgatttttat catttttgtt
    23881 gatcaataca aaaaagatat cctgtttatt aaataaataa tagctaacga ataataatac
    23941 taaagtggcg ataatcatta aaatcctaat catgaacaaa tcctccaaaa taagcaacaa
    24001 atagaaaaag caatttgcca agagcaaatt gctttattct ttaaaagatg gtaatctccg
    24061 ttaatgccgt tgtttgtcct gtagtattga tcccgcgaat tcaagcaggt gggtcccatg
    24121 gtcgtagctt cgaactacca aatgataagg catgttacca gcagtgacac aagacgggtc
    24181 ccaagatatc aataaaaatg ttcggtcaac acacaaagag gacaattcga acatcacaga
    24241 tttcccacct ctatagtagc atatgaattt aaaaagagca atgagagagc tcgcagaaac
    24301 agaaccgttt tcttgtctag ttttttggag gatgcttttt ccactctttt atacggtaat
    24361 actgttgacc cagagcctgt tcatatttcc ctgtatcttt tggctgataa tactgagcat
    24421 tcttcagttt atctggtaaa tattgctgat tgacccaagc ctgatcaaaa tgatgaggat
    24481 actgataacc cacgccacgg ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat
    24541 gatcaggaac atctccagct ttgccctctc gaatatcagc aagtgctgca tctaatgcca
    24601 tgtaggcaga attggatttt ggcgacaagc aaagatcgac gacgacgtct gctagtggga
    24661 tacgtgcctc aggcaatccc aatttttcag cagctaatac agcgttcact gtacgagccg
    24721 cagcagcagg attacctaaa cctatatctt cataaccgat aaccatcaga cgccggcaaa
    24781 tacttgccag atcacctgcc tcaactaaac gggcgagata atgaagtgca gcatccacat
    24841 cacttccacg aatcgatttt tgaaaagccg aaataacgtc ataatgagca tctccatttt
    24901 tgtcatgggt aagagctttt ctttggacac attcttcaat gatcgacagt gtaagatgaa
    24961 tccttccttc tttatctgaa ggagtcgata gtgtagccag ttccagccca ttcaatgcac
    25021 tccgcaaatc gccgttcgtt gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga
    25081 ttgcttgttg tccaaggccg cgttctttat cccttaaagc atgttcgact gccaactgga
    25141 tgtcttgttc tgttaatggt ttgacttcaa agatctgtgt acggctgcgg atcgctggat
    25201 tgatggtaat ataaggattc tcagtagtcg ctccgatcaa gatgattcgg ccactttcta
    25261 aatgaggaag cagaaaatcc tgttttgttt tatctaatcg gtgtacttca tccaataaga
    25321 ggatcactgt accactcatt tttgcttctt ccgctacaac ttgtagatcc ttttttgaat
    25381 ctgtagcggc gtttagcatg cgaaatgcat aattagtaga gccggcgatc gcacttgcga
    25441 tactcgtttt tccagtacca ggaggtccat atagaatcat ggaagagagc atgcgagcat
    25501 cgaccatgcg gcgtatgatt tttccttccc cgactagatg ctgctgacca acgacttcat
    25561 cgatcgttcg aggtctcatg cgataagcca atggctgttg cataggattt tcctccttct
    25621 tgtttttacg tcccttaatt atatcatatt tagcaagatg cctagaaaga acagccttct
    25681 gttgttttgt tttcatagct tatccaacta atattgtgta tgataaagta ggtgagaaaa
    25741 atgacggata aacaaaagat agatgaattt ttttggaata aaacgacgcc agaagtggca
    25801 cgggatttat tggggatgta tttggagcat gacacaccag aaggaagatt agctggatat
    25861 attgtagacg cggaagcata cctaggtcca gaagacgagg ccgcccatag ctatggttta
    25921 agaagaacac cgcgtgtgcg ggcaatgtat gaaaaaccag gtacgatcta cctttacacg
    25981 atgcatactc atcggatttt gaacatcatt actcagccag aagggattcc tcaaggagta
    26041 atgatacgtg caatcgaacc cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga
    26101 aaaactggtc cagatatcag caacggtccg ggaaaattag tggaagcatt agcaattcct
    26161 caagaacttt atggtcagtc tatagcagat agttcgttac gcttagtttt tgagaaaaaa
    26221 aagacaccaa aaaagatcaa tgctttgcct agaatcggta tcccaaacaa aggtgtatgg
    26281 acagaaaagc cgttgcgttt tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa
    26341 aaccaaatcg agaaagattg gggttggagg aaagaaaatg aaaaagaagg atctattaac
    26401 atatttagat gaaataattg aaaaacaagt gacagactat gatgtagctt tagattggga
    26461 tacaaaaaat catacgatcg agatcgttgt tcgcttgttt gcagaaaata aagcacaatt
    26521 tgagattgat gatgcagaag ggatcgtttc gcaagaacca attatcgaat ttgaagacgg
    26581 cgtacttctt tttaatcctc agaaatctgt ttttgatgaa cgcaattatc tagcagtaat
    26641 cccttatgaa ggaaaaaaag ggttggcaaa atcagtagct gattctttag tggaatatct
    26701 aaatgaagta ttagctcaag ggcaaagcga tttgcttgat tttttggatg aagacgatga
    26761 cgaagctgta ttcgagcttc actgggataa tcagcaacta gcagaattag tagaagtaaa
    26821 acagcaaaat gaagcagata cttatttacc gtacccaagt tattaaggag tgacagatat
    26881 gaaatggaat gaagtaaaag tagaaactga aagtgaagca gtcgaagcag ttgctaatat
    26941 tttgatggag gcaggggcga gtggtgtcgc gattgaagat tctttagatg ttgaacattt
    27001 tcagtcggat caatatggtg agattttaga taaaaatgat tttacatcgc tgaaagaagg
    27061 cgcactagtc atggcttatt ttccggaaac gactttctta ccggaaatct tgccttttat
    27121 caaagatcgt atcacacaat tacctgagtt tggtctagct attggaaaaa ataaagtaac
    27181 agttagtgaa gtagaggaaa gcaactgggc aacagcctgg aagaaatact atcatccggt
    27241 gcgtattacg cgaatgctga cggttgcgcc aagctgggaa aactaccaga cagaagatcc
    27301 tctagaaaaa attatcacac tagatcctgg tatggcattt ggcacaggca ctcatcccac
    27361 gacttccttg acattgacag cactagaaac agtcttgcgt ggtggtgaaa cattgctaga
    27421 tgtgggaact gggtcgggcg tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt
    27481 ctatgccttt gatttagacg aagtagccgt tcgttcggcg aaagaaaata tggatatgaa
    27541 tgaaatagcc aaagatgtcc atgtatcagc taacgatctt ttgacaggaa tcgagattga
    27601 aagtgatgta atcgttgcga acattttagc agatatcatc ttattgatga tcccagatgc
    27661 ttggcgttta ctgaagcaaa caggcacgct gatcgtttca ggaatcattg aagagaagaa
    27721 gcaaatggtt ctggatgcca tgttagaaca agggtttatc gtggatcaaa ttttccagca
    27781 aaaagactgg tatgcaatta ttttgaaaaa accagaggtg gaatagatgc agcggtattt
    27841 tttaaaagaa tcatatgaat caaaagacta ttttgtttta gaaggggaaa actatcacca
    27901 cattgtacgg gttatgagga tggaacccga ggatgaagtt tttttggcat tcaatgatca
    27961 aatagccatt gttgcagaaa tcacggagat tactgaagag gctgtttatc tgaaagaaat
    28021 taaaaaagaa gaaaatcaaa aggaactgcc aagttcgatt accatagcga gtggctatcc
    28081 taaaggggaa aagctggatt ggatcgttca gaaatccact gaattaggag cgcaagcttt
    28141 tcttggtttc ccggcatcag cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg
    28201 acaacaacgg cttgaaaaga ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt
    28261 gccatcagta gagttattgg aaacgaaaca agatttattt gagcggctag atgattatga
    28321 cgtggtcttg gttgcttatg aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa
    28381 aattcttagt gaaacaaaac cagatagtcg aatcttagct gtctttggac cagaaggtgg
    28441 attatcccgc gatgaagtcg attattttgt agaacacaaa gggatacttt gtggattagg
    28501 accaagaatc cttcgtacag aaacagcacc tctttattta ttaagtgctg ctagctatca
    28561 atgggaatta atgaatcctt ctttcagcta acgttcttca ttaataaaag agtatcgaca
    28621 gaaagaattg aaaaaatagt caacaatttg tataatagaa acaattattt atacaatgga
    28681 tacgaaaaat cgtttgaaaa agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa
    28741 ctgcacggat tttgggacaa ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa
    28801 aaaagaaagg gggatcgatt cctgtgacaa aagaagaaat tttaacggga cccggtgtca
    28861 taaagctcgt tagtcaatac atgggtcccg aacatgtagc atttgttgag aaagcatgcg
    28921 aatacgcgac tgctgcacat gacggacagt ttagaaaatc aggcgaaccc tacattattc
    28981 atcctatcca agtcgcaggt atattagcag atttaaaaat ggatccccat acagtggcta
    29041 caggcttctt acatgatgtt gttgaagata cagaaatcac tttagaagat ctgagagaag
    29101 aatttggcga tgacgttgct atgttagtgg acggcgtaac caaattaggg aaaataaaat
    29161 ataaatccca cgaagagcag ctagcagaaa accaccgaaa gatgctgcta gcaatggctc
    29221 aagatttacg agttatcatg gtcaaattag ctgatagact acataacatg cgtacgttga
    29281 agcacctgcg agaagataag caaagaagga tcgctcagga aactttagaa atctatgcgc
    29341 ctcttgcaca tcgtctaggg atcagccgga tcaaatggga attagaagat acagcacttc
    29401 gttatctaaa tccaaaacag tattaccgta tcgtccactt gatgcagacg aagagagaag
    29461 aacgtgaaaa atacgtaagt ggtactgttg aagatattcg aatagcgaca gaagagctgg
    29521 ggatttttgc agaaatctat ggacggccaa aacacattta ttcaatctat cgtaaaatga
    29581 aagatcagaa aaagcagttc aacgaaattt atgacttgct agctattcga gtgatcgtag
    29641 attcaatcaa ggattgttat gctgtattag gagcaatcca cacaaaatgg aaaccaatgc
    29701 ccggcagatt taaggattat attgccatgc caaaagctaa tatgtaccaa tctttgcata
    29761 ctaccgtgat cggtccggca ggaaatccgg tagaaattca aatccgaaca caggaaatgc
    29821 atgaaatcgc tgaattcggg gttgctgcac actgggccta taaagaagga aaaaatgaaa
    29881 aagtagaacc agatggtatg acgaaacaat taagctggtt ccatgagata ctcgaacttc
    29941 aagacgaaag ctatgatgct tctgaattta tggaaggcgt aaaaggagat atctttagtg
    30001 ataaagtcta cgtcttcaca ccaaaaggag acgttactga gttaccaaaa ggatccggac
    30061 cattggactt tgcatacagt atccatacag atatcggtaa caaaaccact ggtgcaaaag
    30121 taaatggcaa aatggtgcag cttgattaca aattgaaaaa cggagatatc attgagatca
    30181 tgacttctcc aaattcattt ggcccaagtc gcgactggtt gaaattagtt gctactagca
    30241 aagcaagaaa taagatcaaa cgtttcttca aagcccaaga tcgagaagaa aatgtgatca
    30301 aaggccacga atccgtggtc aaatgtatta cagatctagg atttacgcct aaagatattt
    30361 tgacgaagaa caaactgcaa gaagcactcg atcgttttaa ttatcaaaca gaagatgatc
    30421 tctatgcagc tgtagggtat ggagaagtta gccccttgac gatggccaat cgtctgactg
    30481 aaaaagaacg taaagaacaa aaaatcgagc agcaaaagca agaagcagaa gaaatcatga
    30541 atcagccgaa aaaagaacct gacaaaatga aagtacgtca tgaaggtggc gttgtcattc
    30601 aaggggtaga aaacttacta attcgtatca gtcgctgctg taatccgatt cctggtgatg
    30661 atatcgttgg ttatatcact aaaggcagag ggatatccat tcatcgtcga gattgtccga
    30721 atgttcagcc tgacaaacca aatgtagcag aacgtttgat tgaagtcgaa tgggaagata
    30781 catcgaatac acgaaaagag tatgatgcag atttggaaat ttacggctat aatcgttcag
    30841 gcttattgaa tgatgtactt caaacagtca atgcgctaac gaaaaatctc aacagcgttg
    30901 aagcacggac gaataaagat aaaatggcga cgatccattt gacggttggt atccagaatt
    30961 tatcccacct aaagagtatc gtggataaaa tcaaagcagt acctgatgtc tacagtgtac
    31021 gccggacgaa tggataggag gacagatatg agagcagttg ttcaacgggt aagtaaagct
    31081 gctgtgtcag tcgatcagca agaaattgga aaaattggct acggcctact tgttttatta
    31141 ggcattcatg aaaccgatac gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa
    31201 atgcgtattt ttgaagatga acaaggaaaa atgaatatta gtgtagaaga tgtgggagga
    31261 caaattttaa gtatctctca attcacactg tttgcggata cgaaaaaagg aaatcgacca
    31321 agctttgtgg aagccgcacg accagaaaca gctattcctt tatacgaatc attcaatgaa
    31381 ggaatcagaa gtcgcggcat cacagtcgct accggacaat tcggagcaga tatgtcggtt
    31441 tctctcgtca atgatggacc tgtaacgatc attattgatt ctaaaaacaa ataaagtaat
    31501 ctggttttca ctagtaaaaa ctatgaaaca cgtcgcttaa gttagactga taaactctaa
    31561 cttaagtggc ttttttgtct gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt
    31621 aagcttaaat tatacaagtt attttttata ggaggttgct gaagatgaaa gaagtaccag
    31681 tagtagatat caaaatcaca gatttaaaaa aattgtatca aaaaggatac aacatgttgg
    31741 aggagttacg ccatgaagcg gacgctcccg tcgtcaaagc aaagattttc aataaagaag
    31801 ctatcacgat ctacggatca tcagcagcaa aagtatttta tgatccaagg aatttcaaac
    31861 gaaaaggtgc tatgccaaaa ttagtattga agacactttt tggtcaaggt ggagtacaga
    31921 ctttggatgg agctgctcat caccatcgga aaaatatttt tatggatcta atgacaccgg
    31981 aaagaatgga agattatcat cgtatcttag ataagaatct gacacaagca cttgaagcac
    32041 agcatggtca atttgaacta tttgatttaa gtaagatggt tttctttaca tctatttgcg
    32101 agtgggcagg tatcaattta tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat
    32161 atcaaatctc tatgatcagc ggaacgttta cttctccgat tgatcacata aaaggtgtcg
    32221 aaaatcgcaa aaaatcagaa aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc
    32281 ctgtggctgg aaaagaaaat gtggcattat atgcttttgc caatgccaca gatttagatg
    32341 gtcagctttt acctctggaa gtggcagctg ttgaattatt gaacatcatc cgtccaacgg
    32401 ttgctctaac tgtgtgggcg gcattgatgg gacatgcact tttcagtaga ccagatttgt
    32461 atcagcaatt aaaaaatgac ttttcgacgt tacaagatcc gtttattcaa gaaatgagac
    32521 gctattatcc tttcttccca atgctacctg cgatttcgct gaaagaagta gaagtagatg
    32581 gttatcgtat accagaaggc agttgggtta ttttagattt atatggaaca gaccatgatg
    32641 aacgaacagt tgaagcgcca gattccttta tgatcaaacg gtatgtaggg aaagcaaaag
    32701 atatttccta taaagaagaa tatgagatga ttgcacaagg cgggggaaat tttcgacaaa
    32761 tgcatcgctg tgcaggagaa tggatcactc ttcatagtct acgtgtgttt tccgatcagc
    32821 tagtaaataa gtttgagttc tctgtacctg aacaagattg gacgattcca ttcaatcagt
    32881 ttccgactta tccgaatagc cgagcgctac tttacaagaa ttagattagc ataaacttat
    32941 cgaaaaaaag gaagatcaaa cagtgctgat cttccttttt tcatattact ataaattgat
    33001 aaggtcaatt gatcaaaatc cacgaaatgc ttcatcaatg gtttgataat cttcattgga
    33061 taaatgcaaa tctaaagctt ggacattgtc agatacttgc tctggacgct tagctccagg
    33121 tataactaca gacactcgtg gattcttcat gtaccaagct aaaacaagtt gcgcaggagt
    33181 ggcttggtat cttttagcaa tggggcgaag tacatcgaca gcggttaaaa tttctctgaa
    33241 acgttctcct tggaaatctg gatttctttt tcgaggatct ccttcaccaa attgtttttc
    33301 ctcaccaagt tcatattttc ctgtcagcaa accggaagca agaggaaaat agggaacaaa
    33361 actgattttg tttttttcaa gataagggaa taattctttt tcagcctgcc gatggatcaa
    33421 actgtattta tcttctacta catcgacata tccatctgca ttcgcttctt tcaattgttc
    33481 taacgtgaag tttgacacac cgactgctcg gatttttcct gcttctttta attcgtgcaa
    33541 tgtagcaact gattcatttt ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc
    33601 gatgtaatca gtttgcagac gttttagtgc atcttccacc gattgtttga gaaactcagg
    33661 agaattatca aatgttcgcc ctttatttgg tacatgagca gcttttgtag cgatgacgac
    33721 acgtgagcga tcatattctt tttccttcag tacctcgcca atcagttctt cggaacggcc
    33781 gtttccgtaa gcataagcgg tatcgatcaa attgatcccg ctattcaaag ctgtacgaac
    33841 tacttgtttt cctgtctcat cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt
    33901 tgctcctaat ccaagctgtt ctgcgtagac ttgtgaatgt ccgattctta tttctgccat
    33961 agctgattcc tcctttttgt ctagtctaaa acaaaatacc aaaaagctga actaaaacgt
    34021 ttttgtgagg ggaaatagtc agatatctct tgactttgag actggttttt agtaggttat
    34081 aagtaatatc gaatgtcaat gaaagagcga gtaagttttt gaaactttac aagagaggat
    34141 catcgaggct gaaaatgatc taaagtttca ttagcctaaa gacactctgg agatggacga
    34201 gtgaaaagcc gtcccgcgta cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat
    34261 taggtggtac cgtgtatgaa tttcattcac ccttgttcat gatgaacaag ggtgattttt
    34321 ttatttacat agctaagaaa gggagagaaa actatgagtt tccaaagacc aaaaggaaca
    34381 aatgatattt tgccaggcga atcagaaaaa tggcagtttg tcgaagaaac agcacgttta
    34441 ttattcagag attatcagta taatgaaatg cgtacaccga tttttgaaca ctatgaagtg
    34501 atatcccgaa gtgtagggga tacaacggat atcgtttcaa aagagatgta tgatttttat
    34561 gacaaagggg aacgccatgt gacgcttcga ccagaaggta cagcaccaat cgttcgttct
    34621 tttgttgagc ataaattgtt cggcccagag tatgcgaaac cgttcaaaac tttttatatg
    34681 ggaccaatgt ttcgctacga acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc
    34741 ggagtagaag catttggatc agaaaaccct gcaactgatg tggagagcat ggtgatggca
    34801 cttgatttct tcaaacagtt ggggatcacg caaatccggc tagtcatcaa ttcattaggt
    34861 gataaagaaa cgcgtcaagc ctatcgtcaa gcattgatcg actatctttt accttttgaa
    34921 tcagagctga gtgaagactc taaacgccgc cttcatgaaa atccattacg cgtattggac
    34981 agtaaagaca aacgagatca aaaatttgtg gcagaagctc catctatctt agattatcta
    35041 agcgagcctg ctcaaaaaca ttttgatacc gttgtttcca tgctggatgc attggctgtt
    35101 ccttatgaaa tcgacagtaa tatggttcgc ggactagatt attacacaca tacgattttt
    35161 gaaatcatga gtgacgcacc aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt
    35221 tatgacaatc tagtggaaga actaggtggt ccttcaacac ctggcttcgg atttgcaatg
    35281 ggtatcgagc gattactctt gactatggag gcagaggaag tagttatccc tgcatttaat
    35341 gagttggatg cttacgtggt cgcactcgga gacgaaacaa atatcgaagc attgaaagtg
    35401 gtccaagcga ttcgaaactt tggtttttca gctgaccgcg acttcatgaa ccgtaaagca
    35461 aaagcgcaat ttaagacagc agataaagcg aatgccaaat tagtattggt gatcggtgaa
    35521 gatgagcttg ctagtcaaac gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt
    35581 tttccattag aagagatata tgaacatttt gatgaagtct atgatgaaat gactttattc
    35641 gagtaggagg aaaaaaataa atggcacaaa gaacgatcta ttgcggatta gtttccgaac
    35701 aacaattaga acaaacagtt acattaaaag gatgggtaca aaaaagacga gaccttgggg
    35761 gagtaatctt tatcgaccta cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg
    35821 aaatcaacaa agaagcatgg gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag
    35881 tgactgggga agttagaaga cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg
    35941 aattcgaagt gattgcaagt gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc
    36001 aaattgaaga tgatcaagca atcagtgacg aaatacgttt gaaatatcgt tatttggatc
    36061 tgcgtcgtcc aaaaatgact aaaaacatca aattaagaaa tgcgacaaca aaagcgattc
    36121 gtcattattt agatgataat gactttctcg atatcgaaac accttaccta gggaaatcta
    36181 caccagaagg cgcaagagac tacctagttc cttcacgtgt ccatgctgga catttctatg
    36241 cgttgccgca atctcctcaa ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt
    36301 attatcaaat cgttcgttgt ttccgcgatg aagatttacg tggagaccgt cagcctgaat
    36361 ttacgcaagt agatattgaa acaacgttct taacagcaga agaaatccaa acttacacag
    36421 agggattgat tgcgaaggta atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc
    36481 ctcgtatgac ctatgatgaa gcaatggctc gctacggcag cgacaaaccg gatacacgtt
    36541 ttgatatgga attgatcgat ctaagcgata cagtcaaaga agtagaattc aaagtcttcc
    36601 aaatggctct tgaaaacggc ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc
    36661 gctactcacg aaaagacatg gatcagttag gtcaatatgt aggacaattc ggagctaagg
    36721 ggcttgcatg gctgaaagta gaagaagacg gattgaaagg tccaattgct aaattcatgg
    36781 gagaagcaac agaagcaatc attaaagcaa cagatgcaaa accaggtgac ttgctgatgt
    36841 ttggcgcaga taaaagtgaa atcgtcgctg ctgcattagg tgctatccgg acacgtttag
    36901 gaaaagaatt aggactaatt gatgaatcga aattcaattt cttatgggta actgattggc
    36961 cacaatttga attttcagaa gaagaaggtc gatatgtctc tgctcaccat ccattcacga
    37021 tgccaaaaga agaagatatc ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag
    37081 cttatgatat cgtcttgaac ggttatgaat taggcggagg ttctatccgt attcatactc
    37141 gtgagcttca agaaaaagta ctagaaactc taggctttac aaaagaacaa atggaagaac
    37201 aatttggttt cttgttaaca gctttagatt acggattccc tccacatggc ggtattgcat
    37261 taggattgga ccgttttgca atgttattag ccggagaaga taatattcgt gaagtcattg
    37321 cctttcctaa aaacggaaaa gcagcagatg tgatgagtga tgcaccaagt atggtttcgc
    37381 ctttacaatt gttcgaattg aatattgatg taacgaatat agaagaatag ccgataaaaa
    37441 ggtaaaaagg atttgtcgaa tacgcttctt ttgacaacct tgatttaatt gaaaaacact
    37501 ttataatgaa gccataacat ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt
    37561 gggcttatca tgattacacg accaagcttt cggtatctat cgtttatgcg ttgatcgcat
    37621 cagtcgcatt gaatttcttt tatcagccag gacatattta ttcaagtggt attactggtc
    37681 tagctcagat tttgacgact ttgtcaaaat cactgatagg attcgaagta ccggtatcaa
    37741 caactttgta tttactgaat atacctttgt ttgtattggc gtggttaaaa atcgggaaga
    37801 agtttacaat tttcactttt atcacagtca ctttgacctc cctttgtatc catattttac
    37861 cggaaacagt cctatctacc gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg
    37921 gactaggtat tgggctagcg ttgagaaacg gcctatcatc gggcggtcta gatatcgtga
    37981 gtatcacgat tcgtaaaaaa acaggaaagt cgattggttc tatttcgatc tacttcaatg
    38041 cattgatcgt ttttgttgcc ggaattctat ttggctggca atatatgttt tacagtacgt
    38101 tgtctatttt cgtcagtgga aaagtaactg atgtcgttta tactaaacaa aagaagatgc
    38161 aggtaatgat cgtaacgaaa catccagaaa aagtagtaaa tgaaatccaa aactgtatgc
    38221 gtagagggat cacgatcatc aatgaagcag aaggtgctta taagcatgat aagcagacag
    38281 tattgatgac gatcgttaca cgatacgaac tgcctctact tagagaagca atgaaagctt
    38341 ctgatccaca agcttttgta agtattgcag aaaacgtcca gatacttggt cgtttctatg
    38401 aggatggcat ttagatcgag tttgacaaaa attcatgaaa tactgctgta gacagacgtt
    38461 cgtttgtctg cagttttttt ctaccatagt agaatcagca aagaaaaact gcttttttat
    38521 ttgaaatttt cttaaagttg aaaaaaagca tgtttatttt tttaaattta tgggatgata
    38581 gaaaaaaata gtagagaaag gacacgattc tacttgctat tttcacttaa tacccgtata
    38641 ttacgaatga aaaaagttta tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta
    38701 aaaaacagcc gctacatcac tgggtttgat gggctccgtt cattagctgt ggtgggtgtt
    38761 atcttctatc accttctgcc aactagtatg aaaggcggct atttgggcgt tccgattttt
    38821 ttcgtcgtat ctggttattt gatcacggat ctgctgcggc aggaatggga acaaaatgga
    38881 aaaatcaata tttggcaatt ttatgtcaga agaatgaaga gactctatcc ggcacttgtt
    38941 tttatgcttg tgacagcttc ggcttatatc actttgtttc agcgagggct gttaaacaat
    39001 cttcgaggag ttgtggtcag cagcttactg tatgtcaaca actggtggca aatcaataac
    39061 ggtttatctt atttcgatcg atttgctaat gagtcaccgt ttacgcatat ctggtcttta
    39121 gcagtagaag gtcaaaacta tttggtttgg ccgatcttgt ttgtattgtt gatggtattt
    39181 gttcgtaaaa gaaaatggat cttttatact gtgttaggta catccttcct ctccgccatc
    39241 ttgatgatga tcttgtatac accaggaggc gatccaaccc gtgtttatta cggtaccgac
    39301 actcgtctgt tttctatatg gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt
    39361 ttaaagaaaa acatcccgaa acaagcgaaa aatattctga atatcgctgg aggaatctcg
    39421 cttttggcac tgattctttg cttcttcttt ttagatgatc attacaattt catctattac
    39481 ggaggaatgc tcctagtgag tctgttatgc gtagtgctag ttgcagtgac agcacacccc
    39541 ggagcaagtt tgaatcgatg gctgacaaat ccagtattta cttggattgg caaacgaagc
    39601 tatggcattt atctgtatca gtttccagtt atgatttttt atgaagcaaa ggtgactgat
    39661 attgccgatc atgttttgtt gcatacttta gtggaaatca cattgattct aatcatcagt
    39721 gaactttctt atcgatatgt ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc
    39781 caagtgatga aaggatggtt cagcaaaccg atcatcagta agagcaaacc atgggttgtt
    39841 ccaggcacat tacttgtagc aattgcactc gttggtttcg ttacggcacc gaaaaacgct
    39901 gtaacagccg atcaaaaaca actgcaggca aaaatcgctg aaagtaaaaa attagcagaa
    39961 gaaaccagaa acaattcaga aaacaccact agttcggttg accaagcgat ccttgataag
    40021 tacgagttgt ccaaggcaca agggaataag gcacaaaaat tagaactaac ggcatttggt
    40081 gattcagtta tgttggatgc tgcaacggat ctacaagaac tttatccaaa agtagtggta
    40141 gatggagatg tcggacgaca attatatgcc agtgtaccgt acattgaaaa attaaaggaa
    40201 caagatttgt tgaaagacac tgttctgatt ggactaggaa cgaatggctc attctcggaa
    40261 gctcagtttg atagtgtgat ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc
    40321 cgagtaccga cgaagcgctg gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa
    40381 aaatacgaca atatgacgct gattgattgg tacagctaca gtaatgacca tagtgactgg
    40441 ttttatgatg atcaagtcca tccaaatcct gaagggatga cacattacat tcacttagtc
    40501 agcgaagcct tgctaggagg aagttcaagt acgaacagca gtgagacaaa cgtgacagaa
    40561 tgatagctac aaaaaacttc aggcaaaaac atttgttttt gcctgaagtt tttttatatt
    40621 taccgtgttt ttaacattca tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa
    40681 taacgttctt tttgttttcg ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg
    40741 cttcttgaag aaaatacttc tgcatggatc atcttaacag gtcttctttt ttgaagacga
    40801 gtatatttag caccagtacc attgttatgt tcctctaatc gtctagaaag atcggttgta
    40861 tatccaccat aaaatgtctg atctttacag aataatacgt aaaaataatg ttcatttgcc
    40921 atagagcatc tcacgaatct ctgcagtgta ttctccatcc atattgtaag tgatcaatgg
    40981 tggagcgact ttgaatccgt ctaatttgcc ttctttgatt ccttcaacta acaaaatatt
    41041 tgcctctttt ccaggttttg ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc
    41101 ttccatgacc tgaatgattt ctaagaaccg atcaggacga tggaccatag taaagcgtcc
    41161 atttgttttt agtagcttac ttgaaatatc gatcacttct tctaacgtcg tatgaatctc
    41221 atgacgggcg attgccaggt gtttattagg gttcgtttta tttgttggca gccctttgaa
    41281 ataaggtgga ttacagacga ctaagtcaca agaattatgt cgaacgacag ataagctgtc
    41341 tttcagatcg atggtgtgga cagtcatttg ttcatttaaa tggttaagcg cgatactacg
    41401 tcttgccatg tctgctagac gaggttgaag ttcgatagcg tcgatagccg cctgggttcg
    41461 tttacttaaa aaaagtccaa ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt
    41521 tttaggtaca cgggaaaagt gagcaagcag cacagcatct aaagaaaaag aaaacacttt
    41581 ggaactttgg ataatcttga tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg
    41641 aagcatggat tccctccaaa atgaaaaaaa tagtcgtctg tattatacta tttttattaa
    41701 aaagaaccaa ggtggcttgt caaacctcta ttttttatgc atactatgac cataagaagg
    41761 gaaaggaaga gactatgttt tatcgattta tgcgcggggt agttcgagta ctattagcct
    41821 tagttaatgg aaatgcccgc tatgagaata aagaagtttt accgcaagat gagaattaca
    41881 tactagttgc tccccatcgt acttggtggg acccattata tctggcggta gctgcagcac
    41941 ccaaggaatt cagctttatg gcaaaagaag aactgttcaa aaatccagtt ctgcgattta
    42001 tattaactcg atccaatgct tttccagtta aaagagaaaa tccaggacca agcgtcatta
    42061 aaacacctgt aaagattttg aaatcgacaa atttgagttt gatcatgttt cccagtggga
    42121 caagacatgc tacagaactt aaaggcggaa tggcattgat ttccagaatg tctaaagcga
    42181 aaatcgtgcc agctgtatat caaggtccgt tgacacttgg ggatctgttc aagcgtcaga
    42241 gagtgacagt gcgtttcggc gaaccaatcg acttatcaga tatcaagaaa acggataaag
    42301 aaggtatggc ggagatcgaa cgacgaacac aagcagcttt tgacaaattg gacaaagaag
    42361 tgaaccctga tttcaaatat gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc
    42421 ggtcttttga atctactgtc ctgttcagtt cagacttttt caatgaaaac gagggagaga
    42481 cgtcaagtct gccctctttt tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa
    42541 tggatcaaag tgttataata attagaagga cattttttga ggtgattgaa tgcgtttttt
    42601 acatacagcc gattggcata tcggaaaaaa actacaaggt tatgacttga ttgaagacca
    42661 gcgtcatgta ctatcttcta tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt
    42721 gattgccgga gacttatatg ataggagtgt cccagctgtt gatgccgtag aattatacaa
    42781 tgaattgatg gtcgattgga atttaaagga aaagatcccg atttttgcta tatcaggaaa
    42841 tcacgatagc agtacgagac tttcagcggg tacgccatgg ttcagttatt cgaactattt
    42901 tttgcgaaca cagctagcag aagcatttga accagtcgag tttaaaaacg tacaattttt
    42961 ctttcttcct tactttgaac caattgcagc gagattatat tttgaagatg acaatatccg
    43021 aacgatcaag caagcggtag ccaaggtgat agataaaatg caggagctat ttgattcaga
    43081 aaaaaaacaa gtattgatta gccatttttt tgtaatggga agtgtaaaat ctgattcgga
    43141 aacgaaaatc gaagtaggcg ggttggattc gatccctggt gaactactta caccgtttga
    43201 ttatgtagca ctaggacatt tgcataatca agctgctttg agacaggata atgctcgcta
    43261 tagcggttcc ccattgaaat tctctttatc tgagatcaac caaaaaaaag gcgtatggat
    43321 cgttgacctg acaacaggcc tggagttgaa ttttagggag atcgaacccc tgcatgatat
    43381 tgaagaaata acagcgagtt tcaaagaatt gctggatcct gccttttatc agtccgtcaa
    43441 tcgggagaat tacatctata tctatctcac tgatagaacg atcatcccga atatgatgaa
    43501 ccagcttcgg caaatatatc ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga
    43561 acaaacaaag cgcaaacgaa aagtactaga aatgaaagat cctcaaaaat tagcagaagc
    43621 attttttagt gaaatgacgg aagagcagct aactgcaaac caagaaaaat ggctcggaga
    43681 aacgttgcaa gaaatcatgg aaatggaatg atcaagaatg aaaccgaaaa aattacaact
    43741 taaaaatttt ggtcctttta tcaatgagac cgtagatttt tcacgtttga cagaagcacc
    43801 gctttttttg atcagcggga agacaggagc tggcaaaacg acgatttttg atgggatcac
    43861 cttcgcactt tttggtgaaa cttccggaag acttcgctct ggaaaagaga tgcgttcttt
    43921 gtttgctaca ccagacgaag aaacaagcgt gactttttct tttgaacatc agcagatgag
    43981 ctatgaaatc gaacgaaaac cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa
    44041 aaaacaggca gccaaagtaa cgttgaccat ttttgatggg aaaggaaaag aaataaaaca
    44101 aatcacaaaa cgtacagaag cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa
    44161 acagttttct caaatcgttt tactacccca aggagaattc cgtaattttt tggtttcatc
    44221 aagcagtgat aaagagactg ttttacgtca tttattcggt actcaatttt tccaacagtt
    44281 caatgagcga ttaaaagaaa aagcaaaaca acagcaacaa aaattggatc atttagagca
    44341 agagctgcat cttctgcaaa aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg
    44401 gtttgaagcc gttttagccc aatggacaaa ccatcaggca atactcgaaa aacaaatcac
    44461 ggaagaaaaa gaagctctaa cggaacttca ggaaaaacaa aagcaactag aaaattccta
    44521 ctatcgtttt gaaagcttga aaaaaagtta tgaagaaaaa acgatattaa taaacaagca
    44581 aaaggaatta gctgctcaaa aagacgaaat agaggaaaag aaacgatgga ttgggtatta
    44641 tgaatttacg caacgattag tcgaaccaat ccagcgccta caagaaataa aagttgaaaa
    44701 aatagaactg tcacaaaaaa gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa
    44761 ttatgaagag tggcaaaaaa atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga
    44821 agctgctcaa aaactgcaaa acaaacagat gatggtgcca attgtcgaat ccttacgtag
    44881 taaaaaacaa gacgcagaac aattaacaat ttcattggat aaagaagaat tgaatgccga
    44941 gaagctgtat caaaatctcg ctatctatca ggaaagaact cgaattcttc aagaaaattt
    45001 actggatcag gaaaaactgc aagaagatcg tcttgctttt ggacagttaa aatatctaga
    45061 tgaaaagcag caagaaatag aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat
    45121 aagagaagaa ctcaaaaaag caactgaaga aataacaaaa aatagtcagc tattgaaaga
    45181 acagacagaa caagcagaac agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct
    45241 tcagcttttt ttgcgtccag gggagccatg tcttgtttgt ggatcaacgg aacaccccat
    45301 acaacaatta aaacacgaac agccaaataa ggaagatatc ttaaaagtag aacaacaact
    45361 ggcagaagct gagtctgctg tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca
    45421 tgaaaataat cttcaacaac aattatcaga tttagaacaa aaaatcatgg caacgaatat
    45481 acaattggct gaacaagaag aacacttgca acaggctttg aaaaaggcat ttcctgagat
    45541 aacagaacaa aaaacaaaaa caactcttgt agtaatcgaa caatctttag atagacgaaa
    45601 aagcaagatg gccaatgcaa gaatagagct ggaagaaata agacaacaag cagaaaagct
    45661 cgaacaacaa ttagctgtct acaaacagca gcagacagaa aaaaataatc agctccagca
    45721 actgcaagga gaaatcaaaa gtttagaaca acaattgcaa gatacggata gtaactgttt
    45781 agaagaggag atacgacgac ttgaaaaaca gttagaagaa gactcgaatc aactagctgt
    45841 tgagcagaaa gcaggagtgc aattgttgca agatcttcat acgcttcgga cacagcttga
    45901 tcttcaacat gaacaaatag aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat
    45961 agctaaaaag ttagaaagcc agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc
    46021 acaacagcaa gcacaatata aagaaaacca acgtacagtt acttcttatc atgaagagca
    46081 attagtgaca gctgaccggc tgcgtcaatt agaaaatatc cagctaactg agacattccc
    46141 agatacagaa gagatcagcc aacagttaga agaaataaga cgtatgatcg aaataaagca
    46201 agaaaagata tacggtttac aagaacaaaa aattagtaat caaaaaatct acgatgaatg
    46261 tctttcgatt tatcacacaa gccagacgaa attagatgag cttacgcaat tacagcagct
    46321 ttcgcaaaca ttcaacggag aaaatcctaa gaagactagt ttggaacggt atgtgcttca
    46381 ggtttatctt caagaagtgt tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa
    46441 tcgttatcaa tttgagctag cggataccat tggcagttat cgagggaaaa ccggattaga
    46501 aatcaatatc tatgatgatc aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg
    46561 tgagagtttt attgcagcac tttctttagc attagctctt gccgatgtga tccagacaca
    46621 agctggtggt gtagcaatcg atgcattgtt tattgatgaa ggatttgggt cattagatga
    46681 agaagctttg gaaatggcaa tggaagcttt agaaacgatc gaaagtgaag gaagaatgat
    46741 cggcatcatt agtcatgtaa gagaattgaa agaacgagta ttacaacaaa taagaattga
    46801 tacagaaggt agcggacaaa gcaaaatacg ctatcaactt ggataaaaag ggagattggt
    46861 aactatgaaa tggagtattc cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga
    46921 aggccgagtg ttatcggttg tccctgacca agaagaaaac gtgtggcatg cagaagtctt
    46981 gggcagtgaa ttgtatatgg ttgatttgga tggtacagca aaagagatag attactgcca
    47041 atgtccctat tgggaggaac ataaatattg taagcataca gttgctgtgg aactttattt
    47101 acggtcgaaa aatctatctc gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa
    47161 agcaacaagt gagggagaaa tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa
    47221 tcctcaagcg gtgcaacctt tgattattga ataccaagta gaaacgattg agactaatca
    47281 gtatcaccca gagctttcta ttttggcact ttacttgcgt atcggttcat tggcatcacc
    47341 gaaaaaaaca tatatcgtaa aaaacatcta tgatttttta caagcttaca cagaaaaaga
    47401 aacttacact gttaataaac agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga
    47461 agatcaaaaa atactcacgc atcttgcagg aagtgctcag acgcatcaat tattaggtac
    47521 gaacggctta caagtcaaag gaaaactaga taaaagatat ctgcttctcc cagtagaaca
    47581 agcccgcttc ctgttagagc agatgaatca gactacacgt ttgcatctgc agataaatga
    47641 acaaaacgat caaggaatac aattttccga tcaaaacaaa cctttatcat tcaaagtgga
    47701 aaaatttgga gaagattatt tgctgcaagc attgaatgat tttgattttt tctttatgca
    47761 ttatcagtgg ggagttatcc aagggacatt ttattctctg acgaaatatc aacaaacggt
    47821 ttatcaaact tggaaacaat tgattcgccg attggagaaa ccagaagtag tgttcaagaa
    47881 aaaagaatta ccgtctttgt ttaaagagat tatccctctg ctgtcagaga tcggcgacgt
    47941 agctattgcc cctgcagtag aagaggaagt agcagatatc cccgtcgaat ttattttctt
    48001 tttccgaaaa gcaaaaggaa aaatccaagc tcgagtcgat ttcgtctatg gtgaagtcat
    48061 ctattcgact gacccgaagc atgaggtctc gacagaacag gcttttcagg tgttacgtga
    48121 cacagtagaa gagaaacgag tacttgatct attcagaatg tatcgctacc agaaaaatga
    48181 aactggttat gaacgtccat tgccaagcgg ggaagaacta tatgcctttt tccgcacaga
    48241 actatctgtc ttccgtcagt ttggtgaagt cagacttgga agaaaattgc gagagttgta
    48301 tttagatgcg cataaacatc aaccgaaaat cgaagtaacc gagaccggtt catggctcga
    48361 tattcgattc gatgtgacag ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt
    48421 gctgagaaat gatgcttttt atacattaga aaatggtcag gttctttctt ttgattcaga
    48481 agaatttcaa caaacaagcc aagtgttgca acaattacgg gaatcgatac gtacagaaga
    48541 aggaacgatc catgtaccta aaaatcaagg attgatcatt caaaatcaat tggaaaaaag
    48601 caatgctact tttagtgaat cgttccaaac gatggtacaa gatctcattc atccagaaag
    48661 ataccaggca cagcttccca aaggattgaa tgcaacgatg agagattatc aaaagcaagg
    48721 ttttcgatgg ttgaagatgt taggtcatta tcagtttggc ggtattttag ccgatgaaat
    48781 gggacttggg aaaacactac agacaattgc ctttttactt tcggaaaaag aagaacggaa
    48841 aagcttctct gctttgatcg tagcgcctgc gagcttaatt tacaactggc aggcagaggt
    48901 gagaaaattc gccccttctt taagtatcca agtaatcaat gggaataaaa aagaacgtga
    48961 agaattactg gctaaagaca cagatatccg agtgacttct tatgccagct taagacagga
    49021 tctagctaat tatcagtcgc aaaaaattga ttatttgatt cttgatgagg cacaaatggt
    49081 caaaaatagc agtacgaaaa ctgcacaagc attgagagaa ttagctgtac ctcagcggtt
    49141 tgcactgagt gggacaccaa tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac
    49201 gattatgcca ggatttttcc cgactaaaac aaaattcagg gaacttgccg cagaagaaat
    49261 tgcgcaaatg attcgaccgt ttattttacg gcgagataaa caaactgtgt tgaaagactt
    49321 gccggaaaaa acagagatga atctatattc tgcacttaca gaagaacaaa aaactgttta
    49381 tttagcttac ttgcgtcaaa tgcgtgaaga aatcacatca atggattctg aagcattcaa
    49441 gaaaaaccgg atcgggatac ttgctggtct gacaagactg cgacaaattt gctgcgatcc
    49501 tcgtctgttt attgaagatt accaaggcgg ttccggcaag ctcgaacaag taaaagatct
    49561 actggtagct gccaaagaga acaaacgaag agttttgctg ttttctcaat ttacagggat
    49621 gctgactatc ttgcaagaag agttagccga gctagggatc tcgacatttt atttaagagg
    49681 cagtacgaaa ccacaagatc ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga
    49741 tgtttttctg atttccttaa aggctggggg aactggattg aatctcacgg gagcagatac
    49801 ggtcatcttg tatgaccttt ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc
    49861 acatcggatc ggacaaaaaa atgtggtaga agtgtggcgt atgatctctg aaggaacgat
    49921 tgaggaacgc atggattcac tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca
    49981 aggtaatgaa gaacagttga cgaaactgac tgaagaagac atccgcatga ttttaagtgt
    50041 aggagaaatc gaggagtaag agactcgaaa aagcgttcag taatgggtaa gaaagccttt
    50101 ctaaagaagc gattgtttat ttgatttaaa aaatagcaag gaggctggga ttccatttta
    50161 tcccagcttc cttgctatca tttttttatt tctattttta aaggttatac aaagattgtc
    50221 ttcattgtct ctaacagctg atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt
    50281 tcaattttgc gttctcgatg gttgaaccaa agcgcttgcc agttagcact ttttgcacct
    50341 agaacatcat tgtcgtaatt atcgccaacg tataaggtct cttctggaag catatgaaat
    50401 tctttctcag ccagctgaaa aatctctttt tctggttttt ggaaacctgt tgcttgagaa
    50461 atgagcatat tgcgggaagg aatccaattg ttcaattgaa gttgcttcag tttttttgtc
    50521 tgatggtcag tcggcccatt tgtgataatt cctaatggga cattcttttc cttcaagaaa
    50581 tcgagggttt ttttgacctc ctcatgcaag cagatattat caagttcttc ctcgtaaatt
    50641 ttttgaaata agaggccatc ttcttccgta atatgagggt agtctaaatc ttttagtgat
    50701 tggctgatcc gatgtgctcg catatattct agtgtccaat ctcctgccat tacttttggg
    50761 aagttttcat cactatgatg gcggaaccgg atatatagtg gatgcatatc tgcatctgaa
    50821 acaagcggaa cgactctttt gaccgcgttt cgaaatggct gctgctgatc atacatcgta
    50881 tcatcaacat caaacacaac tgatttaatc aaaattttac acgcctttcg gttttcattg
    50941 attttttcac aaatccttga ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat
    51001 aaaggttttt cttactatat ttctatttcc ttgacagaat aaggttttta tatttcagtt
    51061 tttttcacta aaaatcgtga aacacgtcaa taagtttgat gaacaaatta atcattatgg
    51121 tagaagtcga
//
LOCUS       DAZKCH010000008        50971 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000008 DAZKCH010000000
VERSION     DAZKCH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.008"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(39..863)
                     /locus_tag="ACG84X_000522"
     CDS             complement(39..863)
                     /locus_tag="ACG84X_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFP9126428.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(836..1516)
                     /locus_tag="ACG84X_000523"
     CDS             complement(836..1516)
                     /locus_tag="ACG84X_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFP9126429.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(1539..2477)
                     /locus_tag="ACG84X_000524"
     CDS             complement(1539..2477)
                     /locus_tag="ACG84X_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFP9126430.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(2722..3573)
                     /gene="ispE"
                     /locus_tag="ACG84X_000525"
     CDS             complement(2722..3573)
                     /gene="ispE"
                     /locus_tag="ACG84X_000525"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFP9126431.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(3727..6300)
                     /gene="mprF"
                     /locus_tag="ACG84X_000526"
     CDS             complement(3727..6300)
                     /gene="mprF"
                     /locus_tag="ACG84X_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFP9126432.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            6441..7247
                     /gene="proC"
                     /locus_tag="ACG84X_000527"
     CDS             6441..7247
                     /gene="proC"
                     /locus_tag="ACG84X_000527"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFP9126433.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(7326..8882)
                     /gene="rny"
                     /locus_tag="ACG84X_000528"
     CDS             complement(7326..8882)
                     /gene="rny"
                     /locus_tag="ACG84X_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFP9126434.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(9293..10342)
                     /gene="recA"
                     /locus_tag="ACG84X_000529"
     CDS             complement(9293..10342)
                     /gene="recA"
                     /locus_tag="ACG84X_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFP9126435.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFANPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(10451..11692)
                     /locus_tag="ACG84X_000530"
     CDS             complement(10451..11692)
                     /locus_tag="ACG84X_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFP9126436.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(11932..12510)
                     /gene="pgsA"
                     /locus_tag="ACG84X_000531"
     CDS             complement(11932..12510)
                     /gene="pgsA"
                     /locus_tag="ACG84X_000531"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFP9126437.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(12719..13642)
                     /locus_tag="ACG84X_000532"
     CDS             complement(12719..13642)
                     /locus_tag="ACG84X_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFP9126438.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(14381..15667)
                     /locus_tag="ACG84X_000533"
     CDS             complement(14381..15667)
                     /locus_tag="ACG84X_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFP9126439.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(15660..16928)
                     /locus_tag="ACG84X_000534"
     CDS             complement(15660..16928)
                     /locus_tag="ACG84X_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFP9126440.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            17180..17641
                     /gene="mscL"
                     /locus_tag="ACG84X_000535"
     CDS             17180..17641
                     /gene="mscL"
                     /locus_tag="ACG84X_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFP9126441.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(17700..18146)
                     /locus_tag="ACG84X_000536"
     CDS             complement(17700..18146)
                     /locus_tag="ACG84X_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9126442.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(18239..18484)
                     /locus_tag="ACG84X_000537"
     CDS             complement(18239..18484)
                     /locus_tag="ACG84X_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFP9126443.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(18599..19177)
                     /locus_tag="ACG84X_000538"
     CDS             complement(18599..19177)
                     /locus_tag="ACG84X_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFP9126444.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(19254..19784)
                     /locus_tag="ACG84X_000539"
     CDS             complement(19254..19784)
                     /locus_tag="ACG84X_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFP9126445.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(19788..20648)
                     /gene="rlmB"
                     /locus_tag="ACG84X_000540"
     CDS             complement(19788..20648)
                     /gene="rlmB"
                     /locus_tag="ACG84X_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFP9126446.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(20641..21036)
                     /locus_tag="ACG84X_000541"
     CDS             complement(20641..21036)
                     /locus_tag="ACG84X_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFP9126447.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(21033..22445)
                     /gene="cysS"
                     /locus_tag="ACG84X_000542"
     CDS             complement(21033..22445)
                     /gene="cysS"
                     /locus_tag="ACG84X_000542"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFP9126448.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(22442..22978)
                     /gene="epsC"
                     /locus_tag="ACG84X_000543"
     CDS             complement(22442..22978)
                     /gene="epsC"
                     /locus_tag="ACG84X_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFP9126449.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(23064..23303)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23300..24760)
                     /gene="gltX"
                     /locus_tag="ACG84X_000544"
     CDS             complement(23300..24760)
                     /gene="gltX"
                     /locus_tag="ACG84X_000544"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFP9126450.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(24930..26087)
                     /locus_tag="ACG84X_000545"
     CDS             complement(24930..26087)
                     /locus_tag="ACG84X_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFP9126451.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(26121..27491)
                     /gene="radA"
                     /locus_tag="ACG84X_000546"
     CDS             complement(26121..27491)
                     /gene="radA"
                     /locus_tag="ACG84X_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFP9126452.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(27554..28081)
                     /locus_tag="ACG84X_000547"
     CDS             complement(27554..28081)
                     /locus_tag="ACG84X_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFP9126453.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            28311..29117
                     /gene="proB"
                     /locus_tag="ACG84X_000548"
     CDS             28311..29117
                     /gene="proB"
                     /locus_tag="ACG84X_000548"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFP9126454.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            29114..30361
                     /locus_tag="ACG84X_000549"
     CDS             29114..30361
                     /locus_tag="ACG84X_000549"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFP9126455.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            30437..30781
                     /locus_tag="ACG84X_000550"
     CDS             30437..30781
                     /locus_tag="ACG84X_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126456.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(30898..31224)
                     /locus_tag="ACG84X_000551"
     CDS             complement(30898..31224)
                     /locus_tag="ACG84X_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126457.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(31839..33041)
                     /locus_tag="ACG84X_000552"
     CDS             complement(31839..33041)
                     /locus_tag="ACG84X_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9126458.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            33158..33673
                     /locus_tag="ACG84X_000553"
     CDS             33158..33673
                     /locus_tag="ACG84X_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFP9126459.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(33872..34318)
                     /locus_tag="ACG84X_000554"
     CDS             complement(33872..34318)
                     /locus_tag="ACG84X_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFP9126460.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(34365..35843)
                     /gene="msr(C)"
                     /locus_tag="ACG84X_000555"
     CDS             complement(34365..35843)
                     /gene="msr(C)"
                     /locus_tag="ACG84X_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFP9126461.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(36197..36826)
                     /locus_tag="ACG84X_000556"
     CDS             complement(36197..36826)
                     /locus_tag="ACG84X_000556"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFP9126462.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(36810..37274)
                     /locus_tag="ACG84X_000557"
     CDS             complement(36810..37274)
                     /locus_tag="ACG84X_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9126463.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(37761..39029)
                     /locus_tag="ACG84X_000558"
     CDS             complement(37761..39029)
                     /locus_tag="ACG84X_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFP9126464.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(39260..39997)
                     /locus_tag="ACG84X_000559"
     CDS             complement(39260..39997)
                     /locus_tag="ACG84X_000559"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9126465.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(40064..40633)
                     /locus_tag="ACG84X_000560"
     CDS             complement(40064..40633)
                     /locus_tag="ACG84X_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFP9126466.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            40761..41633
                     /locus_tag="ACG84X_000561"
     CDS             40761..41633
                     /locus_tag="ACG84X_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9126467.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            41975..42847
                     /locus_tag="ACG84X_000562"
     CDS             41975..42847
                     /locus_tag="ACG84X_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFP9126468.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            42844..44802
                     /gene="nagE"
                     /locus_tag="ACG84X_000563"
     CDS             42844..44802
                     /gene="nagE"
                     /locus_tag="ACG84X_000563"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFP9126469.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(45134..45985)
                     /locus_tag="ACG84X_000564"
     CDS             complement(45134..45985)
                     /locus_tag="ACG84X_000564"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9126470.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWVLKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            46108..46575
                     /locus_tag="ACG84X_000565"
     CDS             46108..46575
                     /locus_tag="ACG84X_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFP9126471.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(46838..47320)
                     /locus_tag="ACG84X_000566"
     CDS             complement(46838..47320)
                     /locus_tag="ACG84X_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFP9126472.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(47420..48283)
                     /locus_tag="ACG84X_000567"
     CDS             complement(47420..48283)
                     /locus_tag="ACG84X_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFP9126473.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            48881..49756
                     /locus_tag="ACG84X_000568"
     CDS             48881..49756
                     /locus_tag="ACG84X_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFP9126474.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(49901..50053)
                     /locus_tag="ACG84X_000569"
                     /pseudo
     CDS             complement(49901..50053)
                     /locus_tag="ACG84X_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(50321..>50971)
                     /locus_tag="ACG84X_000570"
     CDS             complement(50321..>50971)
                     /locus_tag="ACG84X_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9126475.1"
                     /translation="TIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDP
                     FLIQNMQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKD
                     FAKLSVTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVV
                     QIPWTTPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
BASE COUNT        14718 a        10835 c         9051 g        16367 t
ORIGIN      
        1 aaatttttcg tttttataag gcttcttttc tttataattt agttattttt tcttctgaag
       61 gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa gactaatgtg
      121 attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga cagcatccct
      181 agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc taatcgcata
      241 ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc aatcgggatc
      301 atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa atgaacgggt
      361 agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg ccgtttgaat
      421 aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac ttgctcccat
      481 gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga attccctccg
      541 ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat ggcaatggag
      601 atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc tgctaataca
      661 acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa cgctacccct
      721 gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat cactaaaaac
      781 acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc tcttctcatg
      841 aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg atctgtctgt
      901 ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat ttcccatgga
      961 catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca tccatacctg
     1021 ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc gctaaactga
     1081 ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata tcccacatcc
     1141 ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga cgcttgaacc
     1201 agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta ggaaaacctg
     1261 cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt ccttcttgat
     1321 ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac gatgctttca
     1381 ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca cccgcatcta
     1441 catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc aaatcagata
     1501 tttcgatata acgcacctta caacctccat tctaaaactt aattgatact ttcttttaaa
     1561 gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat ttgttcatta
     1621 gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt cgacaatgtc
     1681 tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt gtttttcttc
     1741 acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg tgaaacgccc
     1801 gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc agcatgctga
     1861 gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg atccagtgct
     1921 tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt atctggatat
     1981 ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac cggatcgagc
     2041 caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc ttcatgttcg
     2101 tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat caaggtctgt
     2161 ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga actattatac
     2221 acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc gaaatcatgc
     2281 ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac gatctctttt
     2341 gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt tttgtctgct
     2401 tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac cgtagctgtc
     2461 aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt ttacgattta
     2521 ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc atcaatttct
     2581 gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg ctcatatcta
     2641 gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca gtttttcatc
     2701 acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt cctcacaaaa
     2761 accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca aggcaaaaac
     2821 ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca tacgctcttt
     2881 gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt ttcccatttt
     2941 tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt ggatgtcttg
     3001 atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga cactcattct
     3061 tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga tttcttcccc
     3121 tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg taccgacttc
     3181 caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt ggttgatccc
     3241 tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta ctggaatatt
     3301 cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta gcaataaagc
     3361 agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg tttctacaat
     3421 gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta cgctcgacat
     3481 caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca gtcctaaatt
     3541 tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa aagtctaagt
     3601 cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct agtggttgat
     3661 tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa caagttctag
     3721 tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc ctttttcttt
     3781 tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt tcctataagc
     3841 aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag cagactggaa
     3901 ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt gaaagaaaga
     3961 aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt ccgagtagcc
     4021 cattttctcg tatacaataa acagattggc taacagatag tcagctaatt cctcagattc
     4081 tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg gctgagcggt
     4141 gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag ataatacata
     4201 tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa gccatttttg
     4261 tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc aagtaaaatg
     4321 gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag acaagtcttc
     4381 tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac ccaattcatg
     4441 aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc ctaaacaatc
     4501 tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc caactggatc
     4561 tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt gatcttggtc
     4621 gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc ttgtagctgt
     4681 gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac tgccaagctt
     4741 cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg agatgcccaa
     4801 accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat gatttcctgt
     4861 tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa cgataaacaa
     4921 aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga attttgttcg
     4981 ataaaattct tttctggata accacacagc taacagaatc aagacatata ccaatatcaa
     5041 ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta aagcaatcgt
     5101 aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga gtaataaaaa
     5161 gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca ataatacttg
     5221 aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca tcatgatccc
     5281 cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa acagtcgcgg
     5341 aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca atagaagtcc
     5401 cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa ctactgctac
     5461 atcttgccga acagacaatt gactcattcc taagatcatc aaaacgtcaa aagtccccat
     5521 tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca taggatagat
     5581 cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata ccgcaagggc
     5641 tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg gataaaactc
     5701 gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg ctaaaaaact
     5761 accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa taaaaaagac
     5821 atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata gtgcgacttt
     5881 tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac tagcccgcag
     5941 acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg ttacccacgc
     6001 agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta agactctgat
     6061 cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca gaatcatgag
     6121 caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc aactcatgcc
     6181 attagcaata tttgcgactt gatttgccac aaagactaac acggagccga aaaaaatcag
     6241 ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt tatttttcac
     6301 attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc ttatttattt
     6361 taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa agatatccta
     6421 atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat atggcacaag
     6481 ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg ttcgtttcca
     6541 gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat gcatgcaaaa
     6601 gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa ccaaaaatca
     6661 ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc atttctattg
     6721 cttcaggaaa atcattaata gatttagaaa cagcgcttga agatcctcag gcctccatcg
     6781 tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg atttgcaaaa
     6841 atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa gcaatcggca
     6901 gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct ggcagctcac
     6961 ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg aatggtttgt
     7021 ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt caaaaattcc
     7081 tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct ggcggtacaa
     7141 ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc atcaaaggaa
     7201 tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga tagcaatgtt
     7261 ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt cttttgtatt
     7321 ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac tttgatgtgt
     7381 ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa acgaacagcg
     7441 tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc agcttgaact
     7501 gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact tcttaaacga
     7561 cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga gagcgcatct
     7621 gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg atgagaagcg
     7681 atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc accgatctca
     7741 acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag caacccggca
     7801 cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc taattttgca
     7861 acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg cagacgtccg
     7921 atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc tgcctcttcc
     7981 ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat ttcttcgata
     8041 cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg tgcgatttct
     8101 cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc gatgattaaa
     8161 tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc aatgatacga
     8221 cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga aacttgatct
     8281 gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc tgcttcttct
     8341 ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag ctcttcttca
     8401 gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat tttttctagt
     8461 tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc aattaattgc
     8521 tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt ttctaacgag
     8581 tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg agattttaat
     8641 tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg attttcttcc
     8701 ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc actatcgatg
     8761 attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga ctttgcgacc
     8821 ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat gttgaatacc
     8881 ataaaatcca cctccatact atctttttca tttttatcat ctatacagct tctatgataa
     8941 attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa catgcacaac
     9001 tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa acggctttct
     9061 acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat aggtaaacct
     9121 ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata tttttatttt
     9181 atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa aaaacggcag
     9241 gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat ttttattctt
     9301 ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact tcttcaccaa
     9361 taccataagc tgctctaact agagcagaaa cttctgccat catttcagga tgattagcca
     9421 tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa gaataccaag
     9481 caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct ccttcttgtg
     9541 agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt gctactttgt
     9601 tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt ttcaattgtt
     9661 ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt cctccaggag
     9721 tgatttctgg attcgcaaac atcacgccta ctttttcacg gatttggttg atgaaaatag
     9781 cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga gacatcaaac
     9841 gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct cgtggaacta
     9901 aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact aaagcatcag
     9961 cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca tcgatattca
    10021 cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg aaagcggccg
    10081 ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt ttacctgaac
    10141 tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca cctaaagcga
    10201 catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt ttttcgccca
    10261 atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca gcatctaagg
    10321 ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat cagagcaaca
    10381 tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac cgaacaaata
    10441 ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct tgcataaccg
    10501 cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa accacgccgt
    10561 ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac gtgtccggtc
    10621 cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt gcttgaatgg
    10681 ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc tccggatcaa
    10741 tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct ggaaatactt
    10801 cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc aaactttccg
    10861 ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt gctagcgaat
    10921 tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt tcttctaatg
    10981 ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt cgtaatgtca
    11041 cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca atcagatctt
    11101 ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact ttagaaatta
    11161 gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc acaaacattg
    11221 gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct gtttgataaa
    11281 aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg ataatctggg
    11341 actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat gccaataatt
    11401 ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca gttgcttctt
    11461 ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt tcacttcttg
    11521 tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca actgtttgat
    11581 aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca ttcgtattca
    11641 cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc attacttccc
    11701 gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag agggcaagga
    11761 gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc tcctgccaaa
    11821 acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg aaattatccc
    11881 ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata cttacattga
    11941 tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga tagtaaagat
    12001 cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga atgggatatt
    12061 attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt ttcccggcca
    12121 agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg tgacggctaa
    12181 ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt caaccaacat
    12241 gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact tgccaaaatt
    12301 agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga tactagctaa
    12361 agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc ctacgttaaa
    12421 ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca tacaaattct
    12481 aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc ctattctacg
    12541 tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt tattcaaagg
    12601 agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga cacagatttg
    12661 tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat ttatacgatc
    12721 attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt tcccctggat
    12781 taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca ccaatcgtga
    12841 tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt gctgccagtg
    12901 tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga ttgacagcag
    12961 taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg gcactgccag
    13021 aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt gttgattcta
    13081 ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc tcgactgatc
    13141 cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga cgatcttgcc
    13201 aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat aaaatgacag
    13261 gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct tttctagaag
    13321 tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg cttttcccat
    13381 caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat tgccgaataa
    13441 atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg attgcttcca
    13501 aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt tttttattca
    13561 ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca tcttctccag
    13621 tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt tgggtgctgt
    13681 gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct gccaactcct
    13741 cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact tgttccttgt
    13801 gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca atcagctgtt
    13861 cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt atgtttctct
    13921 aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt caaaagcttg
    13981 catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt tacttggctg
    14041 ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg tgttccagaa
    14101 gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat tttcgtaaat
    14161 tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta cttcgtttga
    14221 ttttatttta atataagttg attaaaagag agcatgattt gttttatttt ctcactaatt
    14281 tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc tactacaagt
    14341 ctaaaacgaa atttaagact tttcctcata aaatactggt ttattttggt ctcatgtaaa
    14401 actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg tctttcattt
    14461 ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat aaactttgcg
    14521 taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt ccaagcattt
    14581 tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg aatccaagaa
    14641 tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg ctgaagtccg
    14701 caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg ataattcctt
    14761 gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg aacaacagat
    14821 tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg tctaatcctt
    14881 taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt tgtttgatga
    14941 tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg aaattttttg
    15001 cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta ccaactacaa
    15061 ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag tcttgagctg
    15121 tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg tgtgtaggat
    15181 acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca tacatttgga
    15241 tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag taaggtgctt
    15301 gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta gaaaacagat
    15361 agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc ccaaataatt
    15421 gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg gcaattccat
    15481 ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg atcgaaccat
    15541 aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac aaatacacgg
    15601 tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca tattctgttt
    15661 tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat ttgctcagct
    15721 acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc ttcatcagat
    15781 aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc ttgcggagag
    15841 tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag ttccaactct
    15901 gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag tacttgattt
    15961 cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt atccacgcta
    16021 ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag tttagagtga
    16081 ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg ttcatcgtaa
    16141 tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc acgtacttgt
    16201 cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata aactgtttcc
    16261 cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc aacatcgccg
    16321 acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga cgctagcgaa
    16381 ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt ttgttccggg
    16441 ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt atcttccttc
    16501 aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa ctgatcaaac
    16561 tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac cgcttgagaa
    16621 aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc gtttagccaa
    16681 tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag ctctgcaagt
    16741 tgcgcactta actttgtctg atccgaataa ttcaaactat ttgtttccaa catgctgctg
    16801 agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg gataaaaatc
    16861 cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc tgccaattga
    16921 tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt ttaatgggtc
    16981 aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca attcgccgtt
    17041 ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca aaagaaacag
    17101 acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta aagacaaata
    17161 aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc gtggagatgt
    17221 cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg taaaccaagt
    17281 ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca caggtacttc
    17341 tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg tcacatttgc
    17401 gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg tcttattctt
    17461 agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc aagtggaagt
    17521 ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc ttgccaaaca
    17581 agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata cttctaaata
    17641 ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt tttagattct
    17701 taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc caaatacaca
    17761 tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc ttgtgcgccg
    17821 atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc ttgaacaatc
    17881 tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc aaaatggata
    17941 ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt atcttgaaaa
    18001 aacgtatgcc aagcttctcc atcaatgtca tcaacttctt gataaggaca ctgttgttcc
    18061 acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt tgacaattct
    18121 tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt attcttagca
    18181 taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg tttgcttttt
    18241 aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct gaatagctgt
    18301 aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat actgaaggat
    18361 aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc tgagcaacca
    18421 acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct aaagttgttg
    18481 gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt caagtttacc
    18541 ataaaaaaaa aagaaatgca ataaaaataa ataagaagct cattaagatt tttctaaatt
    18601 attcctcatt ataaaatttc aagtgttttt ttattttgag ttttactctc ccgtaagcgc
    18661 tcattacttg cttgtgatcc attgctaaac attcagccat gtctacaaaa tcaacgcctt
    18721 gcatataata atgaaaaatt ttagcttcta tttttgaaaa ctggatttcg caattttcga
    18781 ttgcttcttt taataaaaga tgctgaattg ctaaaggttc ttgcaatgtg atctctgcta
    18841 aaaagtctgg tccttctgtc tctatttttt ggtcgattga gacttcatct ttttgatcac
    18901 gacgcttcag cgcgttctgc ttcctcaaca gagaatagat ttgattgctt ataacgcttt
    18961 tataataact tccaaagcta acacctttgc ttttttcgta agttctcaat gcctgatata
    19021 aagcgatcct tgcttcttgt tcccaatcct cagaaacata atttcttaaa taataggtgt
    19081 ttttcaaacg tagtaaaagt ggaaaatatt tttgatacag ggcagcaaat gcttcttcgt
    19141 caccattacg tgcagcgcgc aataactcct cagacataaa ataattcctc cataaattcg
    19201 tttatggagg aatcttatca tcaatgattc atcgaactga ttagaacgat atgttattta
    19261 ttttttctca ttaaatcgtc caatttttgg gacaattttt ttaactgctc ttcattccat
    19321 ggagaattac gtcggaaatc aataaaatgc atatctttat tttcttgggc tattgttttt
    19381 tccgtttttt ttatcgtctt atataattca taagcagaag ttcgtaatgc tccttgggaa
    19441 aagatcatcc actgttctgc taaatcgctt gtcgccactg tcacttgtgt caaacggtca
    19501 ttcagctgac cagcgattct ctcgatataa ctgtcagccg tttcgtcttc tttcgtaaaa
    19561 acaacatcca actggtattt cttataattt tgttggatgc ccggaactag ttgggcatcg
    19621 aagacaacga tgacttccat tccttcatat ttcgcataat ttgataaacg atgtaaaaga
    19681 gcttctcttg catccgccat tttgtcctgc tttttaagct ggacaagttc cggccacgaa
    19741 ccaatcatgt tgtagccgtc tacaatcaac agctgttttt tcatggtcta ctccccctga
    19801 cgttgggaaa aagcctgata cataagcaaa ccagcagcaa cactggcatt taagctctgg
    19861 acgtgcccgg tcatcgggat cgtcagcaat tcatccattt cttttttcaa tcctggactc
    19921 attcctttgc cttcattacc aatgactaaa gcaattgatc ctttggcatt ccatttttgg
    19981 aagtttgtgc cggtcatatc tgtgccaaat acccaaaatc ctgtttcttt gagctgttgc
    20041 acagcttgta ccaaattcgt cacgcgtgca acagggacat gttcgactgc cccagtggaa
    20101 gtctttgtta cgataggtgt gattccaact gctcggtgtt ttggtatgat cacaccatcg
    20161 acgccacttg cgtctgctgt ccgtaaaatc gacccaaaat tgtgtggatc ttcgatgcta
    20221 tccaaaatca aaaagaaggg gtcttctttt ttctcttttg ttcgttcaat cagttggtca
    20281 agggataaat attcataagg tgtaatcgca agaacgactc cttgatgcac gccgtgatcg
    20341 ctcaaagttt ctaatttttg tttaggaacc catttgactg gcacagcttg ttcacgtgcg
    20401 atttctttca gttcttctac tttttctcct cgtgaatctt cttgaagaaa gagtttattc
    20461 cctcgccctt gttgtagcgc ttctactgcg gcatggtgcc caaagacgaa attatcttct
    20521 aatgcttctt cattttgatc agaaactgac tgatttcgtc cagtttgctt tttatttgaa
    20581 tatctatttt gttttttgtc ttcaaatcca cgtttcgatt gatgtttgtt tgttctttct
    20641 ttacccattt ttttcaccaa ctttctgaat acaccagcgg atcaattctt ccatccgctc
    20701 ggtttgtttt gtcaaatgca gatagcccat gagcgcttcg aaccctgttg cgacccgata
    20761 cgtcgtaaca tcagcatttt ttgcgctcgt atggctttta gcatttcttc ctctgcgata
    20821 ataaagttct tcttcttctg tcaaaagatg ttcttccagc atttgctgaa tcaaaaaggc
    20881 ttgtgcattc gcagaaacat aattcgttgc cgcacgatgc agcttattgg gttttgtttc
    20941 tccttgatca atcaggtggt cacgaacata gatttcgtaa atcgcatctc caacataagc
    21001 caaggctaaa ccgttcaatt gtgtgtaatc tctcatgctt ctcttctcca tcgggttcct
    21061 tgcggtgtat cttctaataa gatccctttt tctttcaaca aatcacgaat ttcgtcgctt
    21121 cggacaaaat cacgattgct tcttgcttga tttcgttctt cgatcaattg ttcaatctct
    21181 tcatctaata actcttctgc tgtaaataaa ataccgaaga tcgaaagcca ttgcgagaat
    21241 aaagcttctc cttgtgccaa gacagcggca gaaactttcg gctggtctag ataagtgttc
    21301 agccacttag caagctcata gaccactgtg atcccatttg ctgcattaaa atcatcgtcc
    21361 atttcttcga tgaatcgctg ttctaaattt tctaacaaag cgattttatc cgcatcatct
    21421 gccaaattct ctgaggcagt ttcttggcgg aatttcaaat tgtcaaacgt attcttcagt
    21481 cgttgtaaat tggtggctgc ttctttcatc gtcgtttcac tgtagcggat cggacgacgg
    21541 tattgtgtgg tcgccatgaa gaaacgcaag acttgtggat caacgttttt gatcatttca
    21601 tgtacagtga tgaaattccc tagagattta ctcatttttt catcgtcttc gccaatcgtt
    21661 acatagccat tgtgcatcca gtaattagcg aattttttcc ctgttttcgc ttcactttgt
    21721 gcgatttcat tttcatgatg aggaaattct aaatcttgcc cgccaccatg gatatcgatc
    21781 gtttctccta aatgttttgt tgccataacg gaacattcaa tatgccaacc gggacgtcct
    21841 ttgccccatg gtgaatccca agaaatctcg ccaggttttg cttgtttcca taaagcgaaa
    21901 tctaatgggt cttctttttg ctgctgttct tcccctgtac gctgacttgc tccgacttcc
    21961 agttcatcga tggattggtc acttaatttc ccataatttt caaatttacg ggtacggtaa
    22021 tacacatcac ctgaagattc ataagcatag cctttttcaa ccaacacttg aataaatgct
    22081 aaaatatctg gcatatgatc catgactctt ggatgcagtg tagcaggttc gacattcaac
    22141 gctttcgtat cttcttcaaa tgctcggatg aaacgatcag caacttctgg tgctgtaata
    22201 cctaattcgt ttgctgtacg gatgatttta tcgtctacat ccgtgaaatt cgatacgaaa
    22261 tcgactttat agcctcgata ttcaaaatag cgtcgaattg tatcgaaagc aatggtgcta
    22321 cgagcatttc cgatatggat ataattatac acagtcggtc cgcagacata cataccgaca
    22381 tgtccctttt gtatagggat gaattcttct ttttttctgg tcaatgtatt gtagattttt
    22441 atcattctga tctcctcact ttttctcctt tgattcgaac gacttttgct ggtactccta
    22501 ccgctgtagc gtcgtctgga acatctttca acacaacggc acctgcaccg attttggcgt
    22561 tttttccgat cgttaccggt cctaatatct gcgcattcgc agagagcatg gctccttgtt
    22621 taacagttgg gtgtctttta cccgtttctt ttcctgtgcc gcctaatgtt acgccatgga
    22681 ataaaatcac atcgtcctcg atttctgcgg tttcgccaat gacgattccc attccatggt
    22741 cgatgaacac gccagttcca atcgttgctc ctggatggat ctcaacacca gttaggaaac
    22801 gccagaattg agcattgatc ttcgccaata aaaagagccg gtgctgatat aaaaaatgag
    22861 agaaacgatg ccaaaacaag gcatgaaaac cagggtatgt caaaacgatc tcagctgtcg
    22921 aacgtgcagc cggatcgttt ctctttgctg catcaatcgc tcgggtaaac caactcatga
    22981 ctttccactc ctttcgtaag aattttatgt aggaaatcat cttcttataa agaaaagaag
    23041 cgccttttaa ataagtttcc ttatcaaaag acgctttccg cgtggttcca cttttcttca
    23101 taatcaatga ttatctctga cagctaacgc ctgttatacg ttcttggcta ctttgtttcc
    23161 tataaaacag tttttcctgt tttctgtgtt tcgccaagac cactcccaga ggcatttcgg
    23221 caaccattca ttgatacctt gcaccacccg gtatctctct tgtaatgatc agctgcttac
    23281 ttttttctgt tcatcgtgtt tagttcagta cttgatttaa atgtgctaat gatttttcac
    23341 gaccaagcaa ttcgatcgtt tcaggcaatt ctggaccatg catttgtcct gatacagcta
    23401 cacggattgg catgaaaaga ttttttcctt ttacgccagt ttctttttga acagctttga
    23461 tggcagcttt gacagttgga gcatctacta cttccatttg ttctagctgt gctttgaatg
    23521 cgtggagaac agtaggaact gtttcaccag caagtacttc ttttgctgct tcattcaata
    23581 caggatgttc attgaaaaat agcgtagaca gatcaacgat ttctgcagca tagctcattt
    23641 gaggttgata caggctaacg atcttcttca cccattcgat tgtcttttca tctgggtttt
    23701 ctgctacacg tccatcagcg attagataag gcagacacat gtcagtaaat gcatctagat
    23761 ccattgcttt gatgtaatgg ttgtttaccc attgcagttt tttcgcatcg aaagctgcgg
    23821 gtgatttact taggcgtttt ggatcgaaca ttttgatcaa ttcttggtgt tcgaagattt
    23881 cgtcttcgcc cacaggtgac cagcccaata atgcaataaa gttgaacatt gcatctggta
    23941 gatagcctaa ttcgcgatat tgttcgataa attgcaagat tgattcgtca cgtttgctta
    24001 gttttttacc tgtttcactg ttgatgatca atgtcatatg tccgaaggtt ggtggtgtcc
    24061 agccaaatgc ttcatagatc atcagttgtt ttggtgtatt ggcaatatgg tcatctccac
    24121 gtaaaacgtg agtgattttc atcaaatgat catcgaccgc aacagcaaaa ttataagttg
    24181 gcataccatc gcgtttttgg atgacaaagt cgccaccgat attatcggat tcgaacgaaa
    24241 tagcgccttt caccatatct gtaaatgcgt attctgtatt gcgaggcaca cggaaacgta
    24301 caacagattc tagaccttgt gcttcttttt ctgcttgttc ttcaggtgtc aagttcgcac
    24361 atgttcctgc gtaatgaggc atttctcctc ttgcgcgttg tgcttcccgt tctgcttcta
    24421 attcttcttc tgtgcaatag catttgtatg ctcgattgct agcaagcagc tgatcaatca
    24481 gcggttgata gatttcttta cgttcagatt gacggtaagg gccgtattct ccaggatttt
    24541 caggagattc atcccaattc attcccaacc aagcaaggtt ttccaactgg cttttttcgc
    24601 catcttcgat attacgtttt tggtcagtat cctcaatacg aataataaag tctccatcat
    24661 tgtggcgggc aaacaaataa ttgaataatg cagttcttgc atttccaata tgcaggtgcc
    24721 cagttggact tggtgcatag cgtacgcgta ctttcgtcat tttcttcctc ttctttcaaa
    24781 ctagactttg actaacagca aaaattccgt cagttacggc ttctcaaata tcatttattt
    24841 aaagccactc agcacaaatt ttaccttttc taaggtaaat agtaaagcca actggttgaa
    24901 tttccttacc agttggctga atttcttttt tattttgatt gtttagtctt tttctctgtc
    24961 tcttttttat tgtcgattcc tcgtcctgca tgtgcaggtt tagcaaagat catgcgtcca
    25021 gcagctgttt gaagggcact tgttacaacg acttcgatac gttcattcat gtaatgctgt
    25081 ccatcttcta cgacaaccat cgtgccgtca tcaaggtagg ctactccttg ttggcgttct
    25141 gtcccggctt ttactactag aacattcatc gtttcaccag ggatgacgac tggttttacg
    25201 gcatttgcca acgcattgat attaagaaca ggtacatttt ggaattcaga gactttattc
    25261 aagttatagt cattggttac aatgacacca tctaaaagct tagccaattt gatcaatttg
    25321 ctgtctactt cactgatatc ttcaaagtct ccatcgtaca tttcgacaga tataccctct
    25381 tctttttgca aggcatttag gatatctaat ccgcgacgac cacgcacacg tttcaaacta
    25441 tcccctgagt ccgcgatgta ttgtagttcg taaagaacaa aattagggat catcaaggtt
    25501 ccttctaaga atccagtctt tgtaatatca taaatccgac cgtcaatgat cacgcttgta
    25561 tccaagattt tatatttatg gaaattttct cctgattttc gttctaacag ttgactctca
    25621 acttgactag ctgtttcttg ctcgattttt ttgcttcgtg aaccaaaaac tttcttccat
    25681 tcttcgattc gtgtcgttcc cattctcaat cccagatagc ctaagatgat catcagtaaa
    25741 atcggcaata cactattgac gaatggaatt tccatattgt aaagaggggt cgagatcaca
    25801 acacctaaag tcaatccgat gatcgcaccg atcgcaccga agagaagata agtcaagctg
    25861 acctcactta gtttttgttc tacttgtttg ataatagctg agatatgttt ggccaacagc
    25921 aaagataata aaaagaaaat aagtgcgcct aacaggctgt tggtaaatgt attattcagc
    25981 catccgtttg actgttgacc gattgcctgc caagctgagg gtaaaaatga aatacccaag
    26041 cttgcgccga caatgatcat cagcaaagta atgacacgtt tttgcatcgt ttttcctccg
    26101 tttcgacaat catttattag ttagcggaac acacgcttca acgtttcagc caaagttgct
    26161 actccaacta tctcgattcc ttttggcgct tcccagttac ctaagttgtt tttaggtagg
    26221 tatacttttg tgaagccgag tttttggact tctttgactc gttgttcaat atgactgaca
    26281 cgtctgattt ctccagtcag tccaatttca ccgatgaaac attccgttgg ctgtgttcct
    26341 ttttctttat agcttgaagc aatactgaca gcgatagcta aatcaatcgc tggttcattt
    26401 aattttaccc cacctgcagc ttttaagtaa gcatcttgat tctgaagaag caacccagct
    26461 cttttttcca gcactgccat gatcagagat acccgattga aatcaagacc tgttgttgtt
    26521 cgtttggcat ttccgaacat agtaggtgtg actaatgctt ggatctctac caaaattgga
    26581 cgtgtccctt ccattgccac aacgatagca gagccagttg caccgtctag gcgttcttct
    26641 aagaaaatct gtgaaggatt agcgacttct tccaatccat gctcatgcat ttcaaaaatc
    26701 ccaatctcat tcgttgagcc aaatcggttt tttactgctc gcaaaatccg aaaactatga
    26761 tgttgttcac cttcaaaata taacaccgta tccaccatat gttctaacat tcttgggccg
    26821 gcgatcgagc cttctttggt aacatgaccg acgataaaaa tggctatccc atttgtttta
    26881 gcggttttga gtagttctgc agtggtttct cttacttggc tgacacttcc tgccacactt
    26941 gtgatgtctg gctgcgtcat cgtttggatg gaatcaatga taacataatc aggggagata
    27001 tgttcgatgg cacgactgat ttcgttcata tctgtttcag cgtatagata aaattctgtg
    27061 ttgatacttc cgaggcgttc cgcgcgtaat tttatctgct ctgcgctttc ttcgccggat
    27121 acatataaga cttttccgcc tatggctgct aattgctgag aaacttgtaa cagcaaagtg
    27181 gatttcccga tacctggatc gccaccaatc aagaccatag accctggcac cacacctccg
    27241 cctaacacac ggttcagttc ttctaatttt gttttgatcc gaggttcttt tttagggacg
    27301 acgtctgcga tttttgttgg ttttgctttt tctcctgtca aacttgtccg agttctgcgg
    27361 tccgttgtat cttgttcgat ttcttcgacc atcgtattcc attttccgca atttgggcag
    27421 cgtcccaaga acttaggcga cacatacccg caattttggc aaacaaattg tacttttgat
    27481 ttttttgcca ttgtaccgcc tccttttatc ctaatcatga gacattaaat caagcttaag
    27541 tatctttaac gttttattta ctggaagaac caaatccgcc ttgacgttga gcagtcgttt
    27601 gatcttgatc tgcttttaaa aacggcaaaa agatcccttg gccgatacgc tcgccttttt
    27661 tgatcactac atccttgaaa ccaaagttgg tgaattggaa catgatatgg ccttcatttg
    27721 cctcattatt gtaataatca ctgtcaatca cacctactcc gtttgtcaac actaaaaacc
    27781 gcttcaacgg attgcttgaa cggttagcaa gctgcaaaaa ttcatcttct cccatgtaag
    27841 ctttgattcc agtaggcacg agggttggtt tcaattgttt ttcattttct gatacatctt
    27901 ttttcaatcc atctgcgact gtttccaacc cctttttcca gcctgctttc cagatacttg
    27961 gaatcacgac ctcttctgct gcttcaaaat catagccagc agcatgatgt gtagcgcgct
    28021 gcggtagatt gatattttga tctttatatt tagaaataac ttcaaatcct ctttttctca
    28081 ccggttttcc tccctaaata aactactcct attctaacat atccgaggct gtaaaagact
    28141 ttctttacaa attcttcaag aaattctgct atcttaaagt aaaccattaa ttcgttcttt
    28201 ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta catgacttta ctcgtcaaaa
    28261 caagtagaat agaacgaaat taatgagtgg atatttgatt gaggtgtcac atgcgtaaag
    28321 aaattaaaaa tgcaaaacga attattgtca aagtaggaac aagtacattg atttatccca
    28381 atggaaatat caatcttgcg gcaatcgatc agttagcttt tgtcctttct gatcttagaa
    28441 atcggggaaa ggaagtgatc ttagtctcat caggagctgt aggcgttggt atgcataaat
    28501 tacatttgtc agaacgtccg actttgattc ctgaacagca agctgcggcg gctgttggtc
    28561 aagccgaact gatgaatatc tataatcaaa gattcagtgt atataatcaa cagacggcac
    28621 agatcctcgt gacaagagac gtggtagatt atcctgaaag tcgtaaaaat gtgaggaata
    28681 cattggaaca gcttttgatt atggacacga tccctatcgt gaacgaaaac gatactgtag
    28741 cagtggatga attagatcat ctgacaaaat ttggcgataa tgatcagctg tcagccatca
    28801 tggcaaaact tgtcgcggca gaccttttga tcgtcctttc tgatatcgac gggttttatt
    28861 cagataatcc gactacaaat cccgaggctc agatgtatcg ctatatcgat aaaatcgatg
    28921 aaaagattct ggcacaagca ggtggtgctg gtagcacatt tggaacaggc ggtatgcaga
    28981 gtaaattaaa agccgcttct aggatatttg aagcaaacag cgcaatgatt ttagcaaatg
    29041 gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa agaagtaggt actttattta
    29101 aggaggactt gaaatgactg acttgatgca attaggacaa caggcaaaag atagcgcgca
    29161 acaactagca cttatgccta caaaccgcaa aaatgagcta cttgttcaaa tggcacaaac
    29221 catcaaaaag aatcaacaag cgatcattga agcaaatcat aaagacttag aaaaagcagt
    29281 cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag ctgacacctg agcgaatcaa
    29341 tgccatggct acagagatcg aaaaaattgc ttcgttagac gatcctattg gaaaagtaga
    29401 tgagatgtgg acgaacaccg acggattgag aatcggcaaa aagcgcgtgc cactaggcgt
    29461 gatcggcatc atttacgaat ctcgtccaaa tgtcacgaca gatgcagcta gtctagcatt
    29521 caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa gcattcttct cgaatcaatt
    29581 attagtccaa ttattgcagc aagtactggt cagtgctggc gaatctcctt atgccatcca
    29641 gtttgtcgat gatacttctc atgaaactgc aggacagttg atgcgattga cagaatactt
    29701 agatgtgctg attcctcgag gcggagcaaa attaatccaa cgagtcaaag aacaggcaac
    29761 ggtacctatc attgaaacag gtacaggaaa taatcacgta tatatcgata aagaagcaca
    29821 gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct tcccgtccat ctgtctgtaa
    29881 cgcggcagaa acattgctga tccattctga gatcgcacct tttttcttgc cagctattga
    29941 aaaagaactg gtagaacacg gggtctcttt acgtgcggat gctcgtgcgt tagaatatct
    30001 agagacggct gctttagcag aagacacaga ttgggatact gaatatctag attatatcct
    30061 tgctgtcaaa gtggtcgatt ctttggatga agcaattgca catatcaatc ggcataatac
    30121 taaacattca gaaacgatcg tgacagatag ttatgcggct agtcaacgtt tcttaaatga
    30181 agtggacgcg gcggctgtct atgtcaatgc ctccactcgt tttacagacg gatcggtatt
    30241 tggttttggt gcagagattg gtatctctac tcaaaagttg catgcccgtg gtccaatggg
    30301 gttaaatgaa ttaacttcca caaaatatat catttatggc gatggacaaa tccgcgaata
    30361 atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt tctgtaaagg ttctatccaa
    30421 ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt tttatttacc ttatttctct
    30481 gaatatcgct gcttttctgg gagtcggtat tttatccctt ttctttcaat tcaaaaaacg
    30541 aagcataggg agtcaacggg aaaaatggtc gcagtatttt gacaaaatcg ggcaaaaagg
    30601 gctggttaca cgcttgcaca ttagttacat ggttgcatta tgcttattag cgacaatcaa
    30661 ttactattct tttttcgatc attcaatcgc ttatacgatt acgctactga ttgctgggat
    30721 ttttcactta tcttataaat atcagctgaa taaaaaccac ttgaatcgga ctttccgcta
    30781 aaaaatatcc gtacgataag tagagtgcct tgaagatcgg caaaaaactg ccggactttt
    30841 tagaggctgt gacaaagatt ttgtcacagc ctctttttcc atataaacgg cgttcgccta
    30901 ccagctgcct ggtaaatctg tttcctcttc gttaagaagc gaaaatccgt caaatgtttc
    30961 gccatcataa taacgaagca gctcatccat ggacaagttc atcgtttttt ctttttcttc
    31021 ttccgctgat tcagccagta gctgttcccg atacacctga tacataccag ctattttttg
    31081 ctgcatcgct tttctagttt caccttccgc attgattatt ggcaattctt tgatatagcc
    31141 acgataaatc aaccgatcat ctgaaaattc aatgggtaat tcaacgagtg tcaacccgac
    31201 ttcctgaaaa tattcttcca gcatctatta tccccccatt ctttttctta aatgaatttt
    31261 agcttaccta ctgaaaattt tccagtttca ttattttgag aaaaaaaggg aatgtgacaa
    31321 aaatcgtgtc acatcccctt tttccgaata aatggtgttc ttctgccaac tcctcaatca
    31381 taagtcacaa tattcaacaa acatgagaaa ctgttttttg aaattgttcc ttgtgattca
    31441 gagttaaacg acagtctcac aacctcttgg taaacggcgt tcaatcagct gaccctcggt
    31501 attagctcaa aaaacggtaa aatatgagaa gctatttttc cgttttgttt ctctaatact
    31561 taggataaaa cgctgatttt acaacctctg ttaaacggtg ttcaatcagc tgtccttcgg
    31621 tattagctca aaaaacggca aaatatgagg aactattttt ccgtttgttt ctctaatact
    31681 caggacaaaa cgctgatttt acaacctcct gataaacggt gttcaaaagc ttgcatctgc
    31741 ggtaataagc ccaaccaaac gaaaaatatg agaagctatt tttgtttggc tgttcttatg
    31801 acttgatgca ggacagcttt ttcacaacct ctgatttctt attcttcttc atttgtagca
    31861 aaataattac ggtgataaat gatacaacat acactgataa gaacaatggc acctgcaaaa
    31921 taaaacgcat agctttcacc aatatgttca ccaatcacac ctgcaataaa tggtgctaaa
    31981 gctccaccga aaaagcggac aaaactatag ctggacgaag caacgtttcg ttgcagacct
    32041 ggtatttcca tagcaatcgt cgtcaacagt gtattgataa ttccttggaa aaatcctgct
    32101 aacacaatgc tgatcggtac aaggactggc atagaagttc cagctcctaa taacagcaaa
    32161 caaataatga ataagacaaa tgctgctaaa attgtccgat aagtcgtaaa cttccgctca
    32221 agagccggtg caacgaaaat cgaagcaata gccagaagca caccccagcc aaaaaataca
    32281 aaaccgactt ctaattcaga atagccaatc aataaaaatg gcgcatacgc aagtaaagta
    32341 aagaatccga aattatataa caatgcgatt agtccaactg aacgaagttt atgattgctt
    32401 aacgctttga caccttccca aaggcctact tttctctttg gtttctcagt ttcaggtaaa
    32461 agtaccgcta gggctataaa accgcaaaac atcaaaaatg ctaccccaaa aaatggataa
    32521 cgccatgaac cactgcccaa gaccccaccg actagagggc caacagccat tccgcagcca
    32581 agtgctgctt catacatcat gattgctttt tctgtgttac caactaaaat actgacgatc
    32641 gttgctaaag cagtagagac aaataaagca ttcccgacac cccagccggc acgtaaccca
    32701 atcagcattc cgatattccc agataatccg ccaagaccag cgaatacaac gatgataaac
    32761 aatcctgtca tcaatgtttt tttcaaaccg atccgactag ataagaaacc tgtaaatagc
    32821 atcaccacac cagtgactaa catgtaacta gtaaataaca gggtcgtttc agctggcgta
    32881 gcgtttaact gtgcagcaat cgtttttaag attgggtcta ctagacccac tcccataaaa
    32941 gcgatcatac aggtagctgc tacaactagc gctgaacttt tcccctttgt ttcttcattt
    33001 gtttgttctt gtatatctat ttgattctcc aatatttcca tccctttctc tctattagca
    33061 tcatacatga tttattttac atgtcaatat gcacatgtaa aacgtggaaa ctttactgtg
    33121 atataataaa gaaaataaga cgagaggtag gatttttatg aatactttag cctatatatt
    33181 attatgcgtg cttttatcca aaccacgttc tgggtatgaa ttgaagcagc tgatcacaat
    33241 tttttgggaa gcccatcaca gtcagatcta tacaacgctt gccaagttag accagcaggg
    33301 ttatgtgacc gttttggaca aagacgagca ctctcaaaaa aagatctacc acttgactga
    33361 tgaaggacgt gctcttgtag aggaatggat caaagaggaa actcccgctc ctacgcaaaa
    33421 agatgaattt ctagcaaaaa tctatgcttt ttcgacgctc gataaaacaa cagctactgg
    33481 actgctattc actagagaac aacagctgaa caaaatcatg caaaaaaatc aaaaaaaatt
    33541 gaatgacctc tcgctagaca agaaacaaga atttggacgt tatgttgtga tccagcgcag
    33601 aattatgctt tgtcagcagg aactccaatg gtgtcagcaa gtaagagaac aaatgcagca
    33661 gttttttgag taagggataa acagaacctt tctagaaata tctattgaag agcaaattat
    33721 cttcaataaa agagcaatac agttggaaaa gaaaaagcga tccgaacgac aggccaaaac
    33781 ctatcgttcg gatcactatt tttctagaac tgcattcaag agactatgac aaaaagcatg
    33841 ccaaggcctt ttttcaaata acagtgttcc atcattcatt actttgaatt gcttttagca
    33901 cacttcttga aagcgggcca acgatgatca actgcaacgg taaagcggca atcacattca
    33961 ttttccaagc attcatataa gcagagaata attgatcagg tattccttgt tccatgatca
    34021 caccgaataa agacatacat gtcaccattc ctaaaaccat caagcatgaa atagttaaga
    34081 tcatttggac cttgctttct ggatttactg gtagtttaaa ggcaattttt ttcgccagca
    34141 caccgatgat gaagacatcc aaaatgaaag ccaccacgaa tccaggcact agaccaatca
    34201 acaaacttga taaatgaaga tcttgatgca gccataaatt atacgcgctc atccccaaga
    34261 ccatcaaaaa acacatcatt gttgtaaaaa ttattccttc ttttttattt gtaggcaatc
    34321 tgtaccactc ctttaaattt gtcacgaaaa tcatcgtagc acatttaaaa atttctcgta
    34381 agtacttttt ttattttctg cccttttatt tcataaactt catcagccgt acgctcgaca
    34441 aagtaagaat catgagaagt aaacaaaatc gttcccggat atatttgcat tagcttctct
    34501 aaagcttcga tcgttgccat atcaataaaa ttagtcggtt catctaacag caacacatta
    34561 cttggcttag taaaaagcaa agcaatcgtc agacgggtcg cttctccccc acttaatgta
    34621 cataacggtt tcgtcaaagt ttcctgagca aaccctaagt gattcagcaa actacggaca
    34681 agcgattctg aaaactctgt ttgtctcatg acaaaacgaa tgatggattc ttcagatgtc
    34741 atttgataac ccttttgctg atatacttga aagcttactt tcggagagag aaggattcct
    34801 tctccttgtt tgcggatatg ttctaataag gttgtcttac ctgaaccatt ttcaccgaca
    34861 atcgcgattt ttttacctaa agaaaactga aaatcaccat ttaccagtaa tgttctccca
    34921 cttctttcca attggacatt ttgtcccatg atgggatagc ggctgtggag ttcaagagat
    34981 tttggtactg gaaaacggat ttgtttcatc tgctgcggct tggttgtttc tcctattttt
    35041 tggagtcttc tctctaatgt tttcgcattc ttttggatgg ctttttgtac actgtctttt
    35101 tgtttagagg aagacaaccg atccagtctg atttgttgct ttttcttttt actggacact
    35161 ttttccaact tttccgcttg ttttttcttt tcttggatcg atttttccaa tcgttttttc
    35221 tctttcatga tcgactctgc ttctcgtagc tgagtctttt tctccaattc cttttgagtg
    35281 agataggcac tataattccc cgaaaactct cggatttctc cgtcttttac ttcccagatt
    35341 ttcgatgcta gctcatctag aaaatagcga tcatgactaa caaaaaccag cgtaccataa
    35401 taataacgaa gctcttcaat cagtcgatca atactttttc tatctagatg ggttgttggc
    35461 tcgtctagaa gcatcccttg ttcataagaa gaaagaagac gtatcaactc gatctttcgt
    35521 tcttcccctc cgctccattt ccgctctgaa gtttcttcca gtcttaactg gaaatgactg
    35581 gctaattcca aatttaggtc ctttgcttca gcgagatagg ttaattgagg caggtagttg
    35641 aaggtgatct ctgtttggat tttcccatga tcgggaaaaa gttcaccggc tattagtttg
    35701 agcaaagtcg atttaccgac accattttct cctatgatcc ctatacgatc ttgctgatag
    35761 acacgaagag aatcaataga tagttctagc tggttgccaa agctgacttg tagatttgtt
    35821 atatttactg ctaaattttc catatgtttt acactcctat ttcatgtaaa acaacaatta
    35881 tcgatactaa aaaagagcag aaaaatctgt ttgcaaaaaa actgcatcac atcttttcct
    35941 actctgaacg aaataactat gactaaatca ccaaatctgt catagctttc acctattcta
    36001 ctgtcgttcg aaaaaatgga catactccat ccatgaaatt gttgtttata catgtctttt
    36061 gaatttattt agttgttatt caaaagttcg aaacgtaatt tcatcgatgc agtcattttt
    36121 ccgacctcct tttttattag gttaccacac acgattcaaa aaaagcaata gctactgaat
    36181 agtaactgaa aaccttttat tcgaacatag tgatcttttc tggtgctaaa cgaacagact
    36241 cgtaaccttc ttctaccgct tttcctattg ataaaataat aactggaaca taacggtctt
    36301 tatccaaacc aaatgcctct gccaactgat ctgcttcgaa tccaccaatt ggatttgttt
    36361 catagccatg atcacgcgca actaacatga attgcatagc cgctaagcta gaatcgactt
    36421 tgactacatc gttcatttct tctcttgaaa aactcttgta ataaggaatg atcgcagcta
    36481 attgttgatc tctgacttct tttggcatct tccctgattc gtaagcttgg ttgtagattt
    36541 cttcgccata ttcgtaacat tgcatatcgc caaaaatcat gaccattgca gaagaagtat
    36601 cattttgtct cgtattgaaa cggatcaaag gacgcaagat ttcttttgct tcctcgcttt
    36661 cagcgaccac aaagcgccat ggtttcatat tgacagaaga aggtgcagtc gtcgcttctt
    36721 tgatcatttc cagcatttct tcgtgtggga ttttgtatgt ttcatcatat acgcgaacgg
    36781 atcttctacc agtcataatt gttgaaaaat catttttttg ttccattatt attaacctct
    36841 ttcgtttctg ttgttatatt gcaaagttgg gtattcaatt tatctaaaag tgttagaaat
    36901 tgtttcattt ctacatcgct gaaagccggg gatagcacgg aacctgtatc tttatggtcc
    36961 atttcacaat gcttgatttt cttctgggct ttttctgtta gcgctacata cacttcccgg
    37021 ttgttctgag gatttctctg acgcgaaaca tagccatttg cttccaatac cttcagatga
    37081 cgagtaactg ctccttgatc aatctgcaac ttttcttgca aactgctttg tagcaatgga
    37141 ttttcttctt tcagtctcat catgatctcg tatctagtaa gacttatacc gatattttct
    37201 tcaaagatct ggacgatttt ttgatcggct aatttgattt gatataaaag gtgactaatc
    37261 tcttctaaag acataatttc ctcctttcta ataattgact cgtcaacgat tgacttgtca
    37321 ataatagaat aaaaaaagaa aaaagtcaaa gaatcagctg tgtaataaaa aaaacgctct
    37381 caatagaaaa gtatagagaa aagaaatttt ttgtagaatg aacggaaaaa atgataaaga
    37441 aagcacaacg ctaaaaccaa gattattgat tcttatcaaa ctatagaaga tagctcttct
    37501 gcagtagata attttacacc gccaaaaatt tccgaaatcg ccttttgcaa gaatcccgtc
    37561 gaatattaga aattggatca gtatgcttaa acagtaataa aaaagttatg acaagatgtt
    37621 gtcacaacct tttttgagta aacggtgttc aaaaacttgc atctgcggta ataagttcaa
    37681 ccaaacaaaa aacatgaaaa tctgtttttg tttggctgtt cttactactt gatgcagggc
    37741 agctttttca ctacctcttt ttaataacca taaaatccta ttccttcata tctccagccc
    37801 atcggtgtta gccaatctct ttccttagca ctcaaggtat agtgatgggt accagttttt
    37861 tcatttggat taaatagtcg ataaattggc ttggaaccac cagaataaaa acttagacct
    37921 tcataacgcc aaccgatttt tgttaaagag ttgatctcag attgtgccat tgtgtaatga
    37981 tggtctccac tgtaaggatt gtataaacgg tagacaggtt gtccgctgtt tggtgcttgc
    38041 caagcaatcc cttcatattc ccagcctaca gttggcagat aatttttttc tccggcattc
    38101 aatgtatata aatgttctcc tgtatgacgg ttatacagac gatacatcgg agaagttgaa
    38161 gttggtgctg tatcatactg tgtcagatta taggtttcga ttacattgtt caatgtagaa
    38221 ccataattag gcgcagtggc ataacgacct gttagccaag ccgtagcatc tttgtaagag
    38281 ttcgtattgc ttttccatgc accggaatag tagtaaacgc ctggctgaaa agaagtcgtc
    38341 ttcaataccg ttacgttatc ttgcaatgat tctttgtacg aaggatattt tctaaaagcg
    38401 gcattcaccg taatccattg cccattcaca tattccgaag taggcatcgt aacagattgg
    38461 ccattatagc ttcctttaat cccaaataga ttgtaattag gggcagaagc caaagtactg
    38521 ttcccccagc cactttcaac gatggcttga gcaatcatga ctgatgcata taagtcattg
    38581 gcacttgcca aactttgtgc agttgaggca atactatcaa tgaacgcttg ttgagaatta
    38641 gcagatgagc gagcataaaa agcatagcca gtatagtttt cgaattcaga caaatctgct
    38701 tgatgggtat gtgtcaatgt ttgcccatct gtcaattggt tcgtgatttc ttctgcattc
    38761 tctggattgt tctgagcttc tgctgatgta ctgtcttcgg tttgtgtttg ttctgttgtt
    38821 tcagttgttg gttcttcggt tgaaattgta ttttctgaga cagtagctga ctgcaaagta
    38881 ctttctgtat cgttttcaat tcctgtttct gaagaactcg atgtctgagt tgcgacagtt
    38941 tctgtcgatt cttcagctag cactgttgtg ttggcaactg ctagatttcc taaaagaata
    39001 acgctaaata ataaattctt tgctttcatc ttttttctcc tttgaattat gaaacttttc
    39061 ctaaataaca gtgtaactaa aaaagtaaaa gcaagtcaat gtccatattt aaataacatt
    39121 tgtttctttt taataaattt gctttttctg cataaaaaga cgtaaatgaa gaatattctt
    39181 ctccattcac gccttaaatt gatggtcgtt tgaataacta tttaacaagt aattctctct
    39241 ggatattatc cgttatggat tatacttcct gtgtcgtcgg acggataatc atgttgctga
    39301 cagacatccg gtctggcgtt tctatcgcaa atgctacagc agaagctata tcttcagatg
    39361 ttaatcccca ttctttttgc gcttcatgaa gttcaagagc agcctttttg tcgctgatgg
    39421 tttgatataa ttcagtttga acagctcctg gagagatgat cgtagatttg atgttatttt
    39481 gccgttgctc ttgacgtaat ccttccatga ttgcacggac agcaaatttt gttccgcaat
    39541 aaacggcgga atcaggataa acaacatgtc ccgccacaga atcagttgaa atgatatgcc
    39601 cagatttttg tttttccatg attggaagta cggcggaaat tccatttaac acacccatga
    39661 tgttgatatc aagcatattt tgccattcat cacggtgacc ttcaactaat ggagcggttg
    39721 gcatgattcc tgcattattg tacaatacat cgattcgacc gaacttttcc atcgctaaat
    39781 cgataactgc ttggacttgt gcaaaatctc ttacatctgc tgtttgaata tatagctcag
    39841 cttctggtaa agattctttt attgctttta ggcgatcttc tcggcgtgca gctataacta
    39901 gtttagcccc tttttctgct aatagcttcg ttgttgcttc accgattccg cttgaagcgc
    39961 ccatgatgac aatcactttt tctgataaat cattcattct attctcctcc tgttttgaaa
    40021 aatctcttgc ttatactcac tatctcttat ttcatcttac tgttcaaata atccgttcga
    40081 caggtttgac gattttggca gggattcctg caacgatggt attgtctggg acatctttcg
    40141 taacagttgc attcgctgca acaatggcat tctcgccaat cgttacgcct ggcagaatag
    40201 ttgctcctgc tccgatccaa gcatttttct tgatgtggat tggctttact gacaagcctc
    40261 ttcgttcttt tggatcggtt agatggttca ccgtgatgag gttgacacga ggaccaatca
    40321 atactgaatc ttctaaacag atgccaccta agtcaacgaa catcacttga cgattgataa
    40381 agacattttt ccctatacta atatgtttgc cgaaatctgt ataaaaaggc agcagaacag
    40441 tcaccgtatc atctactttg tcactaatga tattttctag ccgtttgcgg atatctgctg
    40501 gttcatggta cccagtattc agcgctgcta aaggctcttc gttttccgct tggatctgat
    40561 ggatcacttc aaagagcgga tccgttactc gaatctcttt attgacgatt tgtttttcga
    40621 tgaggcttgt cattttgctc cctcctttta tccttacttt ataacggacg gcttatgatg
    40681 tctaatactt ataaaacata cttaactatt ccttttaact atacttagtg gtatgctttt
    40741 ttaaaaacag gagggaaaaa atggatattc gtatactgac gtatttttta gcagtagcta
    40801 gagaaaaaaa tatcagccga gcagcaaaat ctctgcatat cacgcaacct actctctcaa
    40861 aacaactgaa agatttagaa gaagaacttg gtgtgacact tttcactcga ggctcccgag
    40921 agatacagtt gacggattct ggtcgatatc tttattcaaa aggaaaagaa atcttgtcgt
    40981 tggtagaaaa aacggcgaac aatttaacaa atgacgcaat catctctgga gaaatctaca
    41041 ttggcggagg cgaaactaaa gcaatctctt tcatttctga tagccttcat tcgttgatca
    41101 aggcgcatcc tgatatccag tttcatttat atagcgggaa tgcagatgat atcatagaca
    41161 aactggatag cggattactt gattttggac tcgtaatcga accgacaaac aaacaaaaat
    41221 accagtcatt tcgactgcca gcccaagatc gttggggact tttgatacat cggaatcatc
    41281 ctttagcaaa gcaaacagtc atccatccgc aggaactgaa aactgttcct ttgatcattt
    41341 cccggcaaac gtcagtggac agtcaactag ctgaatggct aggtttcagc atagatcagt
    41401 tatcgatcgt cggaacatat aacttattgt acaatgcttc tttgatggtc gataacggga
    41461 cttttggtgc attagctcta gatgggatca tcaatactta tgggacggaa aaagtattca
    41521 tcccactcga tccgccatta caagcttcac tgaatctcat ttggaaaaaa gaccagcctc
    41581 tttctcctgc tgctcgtaaa tttttagatg tcctaacgga gaaatacagt taagtagagt
    41641 ttttttcctt cgctttcagc tttttaacaa cgaataagtt aagcaaaaga tccaatgatt
    41701 aaataacata agtttcttaa tttgttcctt ccttttattt ctgataattc cagtaaatta
    41761 ctataattat aaaaaaagaa ttgacaaaac ataactgtct atataaaatt gattacgtta
    41821 acaataattc gtttcatgtg actagatcat actaggcatg aaaaatctct gaggaacatg
    41881 gtttccctag gaggtttttc gtgtctattt ttgtttggcc gcaatcaact ggtctagcaa
    41941 acgtgaaaac caaatcttca aaaagggtgc gcgcatgaaa atcaaaaaga tctttaatca
    42001 aaatgcagta ttggtagatg acggtggaca ggaaaaagta gctattggaa aagggattgg
    42061 atttgacaga aaaagaaatg atttgatttt tgatcgtgat gtcgaacgga tatttgtcat
    42121 ggaaccagaa ggtcaaatca agttgcaaaa tttacttaat cagattgatg aacgcttttt
    42181 atttgcagca gaaacgatca ttgatcatgc ggaaactgtt ttgatggaaa agttgaatga
    42241 acatgtattg atcgctttga ccgaccacat tgctttttct gcggagaaca ttaataacgg
    42301 tatcgtcatc cgcaacaaac ttttaagaga aatcgaagtg ctttacagtg atgaattcag
    42361 tattgctcaa tgggcagtag agtatctgac aaaagagctt gggattccat atacttatga
    42421 cgaagcagga tatatcgcaa tccatattca cagcggacga agcggtcgga acaataacca
    42481 tcgcagtatc cgtgaagtga cgattgtatc tgacatcatc catttagtgg aatcagaatt
    42541 ggaaacagat atccattcag aaccattttc actgaattat tcaagactgg tgaatcattt
    42601 acgactgctt ctacaacgaa cccatgcgca acaatatgct gttttagaca cggaaatcgt
    42661 agaaatggtc aaacgaaaat acccagaaag ctataagatt tctaaaaaaa tccgtgtgtt
    42721 gctgaccaaa gaataccagc tcgcgatcac gaaagaagaa ctgggttact tggccatcca
    42781 tatcgagcgt ttaagaagcg caatcgtaca aacaaatgtt aacaatcatg aggaggaaaa
    42841 aaattgaaag catatctaca acgaatggga cgttcccttc aacttccagt tgcggtctta
    42901 cctgctgctg ctttactagt agggatcgga aactggtggg catcttatag taacgacatt
    42961 gtcgctcatt ttttacaagc tggcggtaac gcagttttag gtcaattacc tttgctgttt
    43021 gccgttgggt tagcactagg gatgtcagtg gacaaatcag gtgctgctgc cttggcaggt
    43081 ttggtcgcat ttgaagttcc agtaaatgtt ttaaaaactg attcagtagc tactttattg
    43141 aatatcaaac cagaatcagt tgatccatct tttgctcaga tcagtaacgt atttattggt
    43201 attattgccg gattgattgc ggcagctctt tataatcgtt tccacgaagc aaaattaccg
    43261 atggctttat ctttctttag cggcaagcgt ctagtgccaa tcttggctgc ctttgtcatg
    43321 ttgctgatca gtgcagtgct actgctcgta tggcctccgg tttactctgc tttagtttct
    43381 tttgctaaat tcattttgag tttaggctgg ggtggtgcag gtctttatgg cttcttcaac
    43441 cgtttactga tccctacagg attgcatcaa gcaatgaact ccgtgttctg gtttgacgta
    43501 gcaggaatca atgatattgg taaatttttg gcttctgaag gaacaaaagg cgtaacagga
    43561 atgtatcaag ctggattttt cccaatcatg atgttcgggc ttccagcagg agcatatgct
    43621 atttacagaa atgcacgtcc agaaaacaaa gcaaaaacag cttccttgat gttagcagca
    43681 gcttttgctt cattctttac tggtgtaaca gaaccacttg aattctcatt tatgttcgtt
    43741 gcttggccat tatatgtctt gcatgcaatt ttcactggga tttctttagc agtgagtgca
    43801 ttcttccatt ggacagcagg atttgccttt agtgccggat ttgtcgatta cttcctatct
    43861 ttgaaaaatc cgattgcgaa tcagccattg atgttgatcg tccaaggatt agtaacagca
    43921 gtgatttact actttggctt taactttgct atcaaaaaat tccatctgat gactcctggc
    43981 cgcgaggaag cagatctttc agatgacgat actgcaacga ctaattcaga caataaatat
    44041 gcggcacaag caagcaaaat ctacgctgca ttaggcggag ccgacaatgt aacttcgatc
    44101 gataactgta ctacacgcct tcgtttgcaa gtcaaagata caggcctgat cgatcaaaat
    44161 aaaatcaaag ccactggcgt acctggtatg aagatcatcg acggaaaaaa tgcgcaagtc
    44221 atcgtaggta cagaagtaca attcgttgca gatgagatgg caaaactaca tggtggtgct
    44281 gcaacacgac ctgcacaaac aaacaccgtg gttaaaacag aaacatttgc cggtggaacg
    44341 atcgaacaag atatttacgc tatcgcaaat gggaaactga ttccaatcac tgaagtttca
    44401 gatgatgtat tcgcggaaaa aatgatgggt gacggctatg ctgtattacc agaaaatgga
    44461 gaaatcttct ctccaatcgc tggtacgatc acaaacattt tcccaacgaa acatgctgtc
    44521 ggaatccaaa cagatgctgg tatcgaagtc ttgcttcata tgggcatcaa cactgttgac
    44581 ttaaaaggcg aaccattcac tttatatgta aaagaaggtc aaaaagtcgc aagaggtcaa
    44641 ttgattgctt tagttgatct tgccgctatt caatctgcag gcaaaaacac ggatatggtc
    44701 gttgtattca caaatggcga caaagtccaa agcttagaaa tcgaacccgc acgtgatgta
    44761 aaagcaaatg ataaaatcgg ctctgtttcc aacaaagcct gagccatcgt cttccccaga
    44821 cttttttatc gataaacaaa caggagctga gacaaaaatc ttgtctcagc tcctttttcc
    44881 gaataaaaac ggcgttctcc tgccaactcc gcggtaataa gtccagccaa acgtaacata
    44941 tgaagagcta ttttttattt gactcttctt attacttgat gcagaacagc ttttttacaa
    45001 cctctgataa acggtgttca aaaaccagtt tatcggtatg aagtcaaatt tatgcaaaaa
    45061 tgtggaaagc cattttcaca aaatttttct tcatactcaa aactaatcgg ctttttcaca
    45121 acctctttat acattattcc tgatccaata tttcttttaa tgctgcttca agagaagtta
    45181 atggttttcc caatactttt tctaaatcat cagaggaaat agctaactga tcctttttaa
    45241 tatcatgttg gatcgctaaa aacatgtcag ctgcttcttg agggaatccg gcttctttta
    45301 gattttcgac aaacgctgca tcacttgctt caataatttc taacttttta cctgtcgcac
    45361 gctctaatgc cttggctaat tcttcatagt cagttagatt gccggataat tctaagattt
    45421 ctggagagtc actttctact agtacttttg ctgcagcttc tgcatattca cgtttcaata
    45481 cccaacctgt ttttccattt cctgcagcat aaacgaattg accagttttt aaagcctgcc
    45541 caatgatagg taattcattc tctacatacc aattattccg taaaaatgta tgggaaatac
    45601 ctgaatcctt aatcattttt tcagtgaatt ggtgatctgg cgctaataca ctgatcgagt
    45661 gatcggcatc tgcaaaactt gtataagcga tataagatac cccagctgct tgtgctgcct
    45721 tcactacatt cttatgttcg gcttgacgat ttcctggaac gccagagaca aaaagcaatc
    45781 gatctattcc tttcaacgct tctttcattg agtctaaatc atcataatca ccaatacgta
    45841 tattaaatcc agcttctttc agtgcttctc ctttttcttc actacgtact agtacataga
    45901 tttcattttg tggaaccatc ttttttaaga attccagcgc ataaccacca aaacctccag
    45961 ttgctcctgt tactaaataa tgcatatttg ccactcccta ttctttttat ttgttaagat
    46021 ttacagctgt acatttataa attacacctt tatcataaag agtgtggtaa gataagtcaa
    46081 gcaaaaaaaa tgaaaggatg acaactgatg aagtattctc tgcaatttag tgatgcaatc
    46141 catgtacttg cctatattga aatgtttcaa gatacccgat cactttctag tgagatgatt
    46201 gccagtagta tcgaaacaaa tgcagcaaat gtacgtaaaa tcatgagtca gctcaaaaaa
    46261 tccggtttga tctttacaaa aaccggaaaa ccgcagcctt cccttgccaa aagtccagat
    46321 cagatttctt tactagatgt ctatcgcagc atcgaaggta atacacagct tatccaagtc
    46381 gatccaaaaa caaatccaaa ttgcgtcgtt ggtgcgaata tccaagaagc tttagaagaa
    46441 agctacgctc ggctgcagaa aaaggcagaa gaagaaatgg ctaagatcac acttgatagt
    46501 ctgatacata aaatagccgt tttggaaaaa gaaaaaagac cagaaaacac aggcctcgta
    46561 gagagatttt tataattctc tctactgtgc ctgcattttt ctgatcggaa tcgtctacat
    46621 aaattctttt attctccggg ggacaaaagc cttgtcatgc ccctttttcc tctctaatgc
    46681 tcaggtcaaa gcgctgaagt catgacgtct tgataaacgg tgttcaagta gctgaccctc
    46741 ggcattagtt ctgaaaaatg caaaatatgg aaagctattt cccatttttc ctctctaatg
    46801 ctcaggtcaa agcgctactt tcacgacctc tatattatca tggtttattg actaccggta
    46861 tccagatttc tcccatatat ttcccgttgg taactcccat ttcgactaca gcatttggac
    46921 ccccaacata ggcgtaatct tctacttctc ttaaaacatg cccaaaggcc gtattcgtca
    46981 aatcatttct taattcttca ggcgattctg ctaaagcgat tacaacaaga tacgttcctt
    47041 ttgggaatgg gatgattcgg gtagtgtttg gaacatcctg actcgtttga acaccgacat
    47101 agtacatcat tttcccgtta tagggttcgt tgactgtaaa gaaataatga ttttcagcag
    47161 cttgtttcaa tgcatctatt gttccattac cgataacttt ttgctcaaat gcttgtttct
    47221 ctgcagccaa accgacaaaa tccgtattgc tactcttcaa ttccacacca atacccgtca
    47281 ccgtaaaatc tggtttttct tcgatcctat actttgccat ttctcccacc ctttctatta
    47341 tattaagttc atcttacata aaattaaagg gaaatgacac gattacgctc ttttttctag
    47401 ggatattttt attttttaac tatttttttg ctttcactgc aatccaaatc tcactgtaaa
    47461 cattactgaa atcctctccc cattttgtaa aagagatctc gggagcttcg actaactcat
    47521 aatctgaaga aggaagccat tctgcataga ttttccccca agtatcttgt aaagtttggg
    47581 gaaatggccc tttattagga aaaatggccc aagtgtgttc ttctatagca agcatttcta
    47641 aatcagcgta cggattttct tttgtcgtag caaagccaat catgtgcatc aaactgccct
    47701 tttcttccaa gcgggctcca tcaaatccat aagaaacgtt gattacttga tttggatata
    47761 aatctcctaa cttatgcatc tcttcccttt gagtctccgt gatcgtctgc gctaactttt
    47821 gtatttcttg attgactcct tcaaatttga caggaacttt tttcgccaca cctgccacat
    47881 aaaactgttc tttcttttcg atacgaaatt ccatcgattt tcctcctctg acatcaataa
    47941 aaaatgtcaa gcgtggaaaa gatttttgta tgccgtatct gctgatttct gaaggcagat
    48001 atcctgacca atcacgaaaa gctcttgaaa aaccttcgac tgtttcatat ccatatctaa
    48061 acgccgtttc tgtcactctt gatccatcta ggagatcgcg attagccaaa gccaatctac
    48121 ggtttttgat atagtccatt agcgacatcc ctgcaataaa cgtaaagatg cgttttaatt
    48181 gatattcaga gattcctgta ttttcggcta ttattttata ggaaagtcct tctgtcaaat
    48241 gttcttcgat gtaatcgatc aattggttca gatctttaag catatttatc ttcctccttg
    48301 cttgcctttt tatcatatta tcaaagaaag tcaattactt gatgaatcag gaaccaattt
    48361 agtcagatgt agaaaatgtt gtatggatct aaagaaaatt ctcaagcagc gtttcgtaac
    48421 ggataattgg tattatctgc ctatctatgt tttaccttta gaaaaataaa ttttggggaa
    48481 gacacattct aagtaaacaa agcggtaaaa atatctttta ttcccttagt taatccgctt
    48541 actacctact gtacaaagca aattgttgtt caaactgctg atcagaacgc tgcttggatt
    48601 tttctttgcg atacatcata cctcttttat caattggaac aattatttat ttctaacaaa
    48661 atcacttcat ttttgtcaga taaataaaaa acaaaaaaag ttccatcttt aaaacacgct
    48721 attcttttac tttttctcac attctctaag aaaagaaaag gagaatgaat ttttgacaat
    48781 tcgagcaaaa gtgattatca aatatgtaaa atcagctact tttttcttaa acgtttcttt
    48841 atactaaata taaataagtg tttcatgaaa ggagaactag atgaataatt ggcttgagta
    48901 ttttcctgaa aacgttttgg aacgcggtta cagctatcat ctgcacggtt ttgtccgtca
    48961 tttgaactat acaagcaagt acttgtccgc aacagtttct ggcacggaag attataaggt
    49021 agtgatcact tgggatgaaa agaccaacat gacttgtgat tgtctatatg ccatagaagg
    49081 aaaaaaatgc aaacacatgg ctgctgtctt attcgcttac gaagaacgtc caataaaaaa
    49141 atccaactac tcactttccg aactctcgtc ccttgtttcc tccgctagtt cctctcttgt
    49201 acgggagctt ttaacagaga ttcttataga acatccgcaa tttatcgaac gcttcaaagt
    49261 taagatgcca tttcatgcaa taaattattc agataaatta acaactatca tccataaata
    49321 cgatcatatt atcaagaaaa acaaaaacag gaaaacagcg aagttcatca tggagatgcg
    49381 aaagttcatc caagaagcag ttgaatcgct cattcagcaa aatgcctatc ttcccgcatt
    49441 cgaattgatc aatgaagtga ttgctactct cgaaacattc tattgggagc ctgaggatga
    49501 acgaaccctt cttctgatag aggactgtta ttatttatgg aaagaattat tagcagaagc
    49561 acctcatgca gaaaaaaggc aaatgttctc ttggttcgtc tgccaagtcg atcatactga
    49621 cgcctcttat tcaaaacgct actccataaa aatcctgaaa gaagactttc gggaaaaaga
    49681 attttctaac caaaagaaaa aaatagataa aaaaactaaa gaaacggtaa agaaagacga
    49741 tttcaatgaa aaatagcaag taaacgataa caaccatcct aaatccacaa gaaatacagc
    49801 agaccttgct ttaaaaacac gaatcatgca aaggatgaag taaagaagac ttaacgcgta
    49861 cccaatatta gtcatttgac tattaggtac gcgttttgtt ttataagtca tgacaaattt
    49921 ccttcgttgc tgggtagatt ttccggcatt gttgatagat tttatgatac ttttctacat
    49981 tttgtaagag aggttccact gcatctgtat attggataaa attctgacaa caactttcag
    50041 gtgtgtcgaa ccactctaat ctttaaagat aaatattaaa ataacgatta ataatattaa
    50101 cagtctttat ttttcaccac caaaaaccta tctttgcata tactaaatag acgtatatac
    50161 acagataggt ttgtcttgtg aaaaataatg attatcctta ccaaaaaatg tttgtttttc
    50221 tacatgttcg tacttatcaa aaaatatgat ccttattgaa attactggct atttatattc
    50281 caacgacttc ttgtgttaat ttttgttatc tcatagtaaa ttatgtttca ttttcactta
    50341 atttagttgt cacgtgttcg tcaattcgta aaaacggtaa atatataaac acacttgcgg
    50401 ctataattaa tatttgtaaa acagctgctc gccagtctcc ggctgttgct aaaaatcccg
    50461 atataactgg tggcgtagtc caaggaattt gcactactac atgattaatt aatcccacag
    50521 cagttgcaaa atatgctact gtcaaagaaa aaatcggtgc aagcacaaag ggaataatca
    50581 gactgatatt aaatacaata ggcaatccaa aaataatagg ttcgcttata ttgaatatag
    50641 cgggagttac cgataattta gcaaagtcct tataatcttt tctacgactg aagataaata
    50701 ttgcaatcaa taaagcaatc gtatttcccg atccacccat taccgcaaag gtatctttaa
    50761 aggccatatt gataatatgt ggaatttgct ctttgtttgc ataagctgcc atattttctt
    50821 gcatattctg aatcaaaaac ggatctaaca atgaacctga tattactgct tgatggatac
    50881 caaatccaaa aaatagatta gcaatagatg taattaacaa aaatcctggt aaaccagttg
    50941 taattttact taatggctct gtaactatcg t
//
LOCUS       DAZKCH010000009        49977 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000009 DAZKCH010000000
VERSION     DAZKCH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.009"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..167)
                     /locus_tag="ACG84X_000571"
     CDS             complement(<1..167)
                     /locus_tag="ACG84X_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFP9126476.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLV"
     gene            complement(169..366)
                     /locus_tag="ACG84X_000572"
     CDS             complement(169..366)
                     /locus_tag="ACG84X_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFP9126477.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(760..2487)
                     /locus_tag="ACG84X_000573"
     CDS             complement(760..2487)
                     /locus_tag="ACG84X_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFP9126478.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2480..3673)
                     /locus_tag="ACG84X_000574"
     CDS             complement(2480..3673)
                     /locus_tag="ACG84X_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFP9126479.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3860..4504)
                     /locus_tag="ACG84X_000575"
     CDS             complement(3860..4504)
                     /locus_tag="ACG84X_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9126480.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4598..4732)
                     /locus_tag="ACG84X_000576"
     CDS             complement(4598..4732)
                     /locus_tag="ACG84X_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFP9126481.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4734..6866)
                     /gene="feoB"
                     /locus_tag="ACG84X_000577"
     CDS             complement(4734..6866)
                     /gene="feoB"
                     /locus_tag="ACG84X_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFP9126482.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6863..7336)
                     /locus_tag="ACG84X_000578"
     CDS             complement(6863..7336)
                     /locus_tag="ACG84X_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFP9126483.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7737..7961
                     /gene="nrdH"
                     /locus_tag="ACG84X_000579"
     CDS             7737..7961
                     /gene="nrdH"
                     /locus_tag="ACG84X_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFP9126484.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8120..10279
                     /gene="nrdE"
                     /locus_tag="ACG84X_000580"
     CDS             8120..10279
                     /gene="nrdE"
                     /locus_tag="ACG84X_000580"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFP9126485.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10329..11294
                     /gene="nrdF"
                     /locus_tag="ACG84X_000581"
     CDS             10329..11294
                     /gene="nrdF"
                     /locus_tag="ACG84X_000581"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFP9126486.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11383..12522)
                     /locus_tag="ACG84X_000582"
     CDS             complement(11383..12522)
                     /locus_tag="ACG84X_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9126487.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12831..13544)
                     /locus_tag="ACG84X_000583"
     CDS             complement(12831..13544)
                     /locus_tag="ACG84X_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFP9126488.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13798..14499)
                     /gene="nagB"
                     /locus_tag="ACG84X_000584"
     CDS             complement(13798..14499)
                     /gene="nagB"
                     /locus_tag="ACG84X_000584"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFP9126489.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14733..16265
                     /locus_tag="ACG84X_000585"
     CDS             14733..16265
                     /locus_tag="ACG84X_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFP9126490.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16456..17658)
                     /locus_tag="ACG84X_000586"
     CDS             complement(16456..17658)
                     /locus_tag="ACG84X_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9126491.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17740..18429)
                     /locus_tag="ACG84X_000587"
     CDS             complement(17740..18429)
                     /locus_tag="ACG84X_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFP9126492.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18535..18903)
                     /gene="rplL"
                     /locus_tag="ACG84X_000588"
     CDS             complement(18535..18903)
                     /gene="rplL"
                     /locus_tag="ACG84X_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFP9126493.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(18956..19459)
                     /gene="rplJ"
                     /locus_tag="ACG84X_000589"
     CDS             complement(18956..19459)
                     /gene="rplJ"
                     /locus_tag="ACG84X_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFP9126494.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19663..19790)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(19869..20558)
                     /gene="rplA"
                     /locus_tag="ACG84X_000590"
     CDS             complement(19869..20558)
                     /gene="rplA"
                     /locus_tag="ACG84X_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFP9126495.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20662..21084)
                     /gene="rplK"
                     /locus_tag="ACG84X_000591"
     CDS             complement(20662..21084)
                     /gene="rplK"
                     /locus_tag="ACG84X_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFP9126496.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            21427..22095
                     /gene="sdaAB"
                     /locus_tag="ACG84X_000592"
     CDS             21427..22095
                     /gene="sdaAB"
                     /locus_tag="ACG84X_000592"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFP9126497.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            22108..22980
                     /gene="sdaAA"
                     /locus_tag="ACG84X_000593"
     CDS             22108..22980
                     /gene="sdaAA"
                     /locus_tag="ACG84X_000593"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFP9126498.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(23071..24171)
                     /locus_tag="ACG84X_000594"
                     /pseudo
     CDS             complement(23071..24171)
                     /locus_tag="ACG84X_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(24263..25150)
                     /locus_tag="ACG84X_000595"
     CDS             complement(24263..25150)
                     /locus_tag="ACG84X_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9126499.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(25227..25772)
                     /gene="nusG"
                     /locus_tag="ACG84X_000596"
     CDS             complement(25227..25772)
                     /gene="nusG"
                     /locus_tag="ACG84X_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFP9126500.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(25873..26043)
                     /gene="secE"
                     /locus_tag="ACG84X_000597"
     CDS             complement(25873..26043)
                     /gene="secE"
                     /locus_tag="ACG84X_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFP9126501.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(26067..26219)
                     /gene="rpmG"
                     /locus_tag="ACG84X_000598"
     CDS             complement(26067..26219)
                     /gene="rpmG"
                     /locus_tag="ACG84X_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFP9126502.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            26381..27025
                     /gene="cbpA"
                     /locus_tag="ACG84X_000599"
     CDS             26381..27025
                     /gene="cbpA"
                     /locus_tag="ACG84X_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFP9126503.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(27081..27584)
                     /locus_tag="ACG84X_000600"
     CDS             complement(27081..27584)
                     /locus_tag="ACG84X_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFP9126504.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27597..27643)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            28181..29146
                     /locus_tag="ACG84X_000601"
     CDS             28181..29146
                     /locus_tag="ACG84X_000601"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFP9126505.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(29245..30417)
                     /locus_tag="ACG84X_000602"
     CDS             complement(29245..30417)
                     /locus_tag="ACG84X_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126506.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(30404..31549)
                     /locus_tag="ACG84X_000603"
     CDS             complement(30404..31549)
                     /locus_tag="ACG84X_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126507.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(31563..32487)
                     /locus_tag="ACG84X_000604"
                     /pseudo
     CDS             complement(31563..32487)
                     /locus_tag="ACG84X_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            32604..33683
                     /locus_tag="ACG84X_000605"
     CDS             32604..33683
                     /locus_tag="ACG84X_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFP9126508.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            33680..34308
                     /locus_tag="ACG84X_000606"
                     /pseudo
     CDS             33680..34308
                     /locus_tag="ACG84X_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(34418..34645)
                     /locus_tag="ACG84X_000607"
     CDS             complement(34418..34645)
                     /locus_tag="ACG84X_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9126509.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(34748..37336)
                     /locus_tag="ACG84X_000608"
     CDS             complement(34748..37336)
                     /locus_tag="ACG84X_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFP9126510.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(37356..38015)
                     /locus_tag="ACG84X_000609"
     CDS             complement(37356..38015)
                     /locus_tag="ACG84X_000609"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFP9126511.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(38064..38567)
                     /gene="trmL"
                     /locus_tag="ACG84X_000610"
     CDS             complement(38064..38567)
                     /gene="trmL"
                     /locus_tag="ACG84X_000610"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFP9126512.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(38788..39654)
                     /locus_tag="ACG84X_000611"
     CDS             complement(38788..39654)
                     /locus_tag="ACG84X_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFP9126513.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            39763..40404
                     /locus_tag="ACG84X_000612"
     CDS             39763..40404
                     /locus_tag="ACG84X_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFP9126514.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(40466..41827)
                     /gene="mgtE"
                     /locus_tag="ACG84X_000613"
     CDS             complement(40466..41827)
                     /gene="mgtE"
                     /locus_tag="ACG84X_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFP9126515.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(41845..42744)
                     /locus_tag="ACG84X_000614"
     CDS             complement(41845..42744)
                     /locus_tag="ACG84X_000614"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFP9126516.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(42746..43543)
                     /locus_tag="ACG84X_000615"
     CDS             complement(42746..43543)
                     /locus_tag="ACG84X_000615"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFP9126517.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(43521..44225)
                     /locus_tag="ACG84X_000616"
     CDS             complement(43521..44225)
                     /locus_tag="ACG84X_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFP9126518.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            44356..44932
                     /locus_tag="ACG84X_000617"
                     /pseudo
     CDS             44356..44932
                     /locus_tag="ACG84X_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
     gene            45050..45727
                     /locus_tag="ACG84X_000618"
     CDS             45050..45727
                     /locus_tag="ACG84X_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFP9126519.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(45806..47614)
                     /gene="pepF"
                     /locus_tag="ACG84X_000619"
     CDS             complement(45806..47614)
                     /gene="pepF"
                     /locus_tag="ACG84X_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFP9126520.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(47790..48788)
                     /locus_tag="ACG84X_000620"
     CDS             complement(47790..48788)
                     /locus_tag="ACG84X_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFP9126521.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(49014..49667)
                     /locus_tag="ACG84X_000621"
     CDS             complement(49014..49667)
                     /locus_tag="ACG84X_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFP9126522.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        14960 a        10488 c         8770 g        15759 t
ORIGIN      
        1 ttcaccaatc tatttattaa aggaccggga tctaattcat atttttgttt ttctaatttt
       61 aaatatacct tttgtaaaac ctcaagaata tcagaatatt taggatcttt acttatagat
      121 atatcattat ataattcatg aacaatttgc ttagcatttt ttttcatttt agcacttccc
      181 tggaattgct ccacctaaaa aaccacctat agacattcct gcaatacaag tagttgcctt
      241 ggcccaatcg accgtacatt tatttttagt gcaatacact ccatttccat aatattttcc
      301 actatgagtg gtacccccat agataagttg tgtctcttta atagacaaaa tttttaaatg
      361 tttcataatc taatcacccc taaattaatg tttttagact attattctaa cattcattaa
      421 atttcaaaaa acaattcctt cttgaaacgt agcaaaataa ttcctgaata agaatttaat
      481 cacttttaag tatataaact atgtatattc tttaatattt tttgagaatg cacttcgtac
      541 ataataaact ttaatcacat tagtctttca tacctacgat cgatctcttt gactcgcacc
      601 cataaattca taatagtttg tcggcgtctt tggacgtttc gaagatgagc tacgcattct
      661 ctttttttat agacaaaaaa gatagagacg aacatggagc ttccaaattt ggatatttga
      721 tccaattttg gaagctccat ttatttcgtg tctgtctttt tattttttcc agctttcgac
      781 taattcttgg ttctctttga tccagtcttt tgctgcttgc tgtggatctt ttccattgtt
      841 gatttccaac ataacttttt ccatatcttt ttctgaccaa tggaaattgt ctaatacttt
      901 gtaagcttct ggctggtctt ctttcaatcc ttttcgaacc atcgtatgga tctgctcttc
      961 gcttcccatt ccgttttcag gatcttctaa gtatttcaga tcatatttgg caaacatcca
     1021 atgaggtgtc catcctgtaa ctacaattgg ttcgtgtttt ttgatcgctt gacctagtgc
     1081 aacggtcatt gctcctgaag aagatgtctc tactttccag tctttcaagt tgtcatattt
     1141 ttggatcgtg ttttcagcag ccgtaactac accagctcct ggctcgattc ctatgatttt
     1201 cttacctgcc tgatcggtta actcatcgat cgaatttaca tccatgtagg ctggcactgc
     1261 taaaccaact tttgctcctg tcaaattggc acctaggtct tcgacttgat ctttatattg
     1321 tgcatattgt gaaccatgag ttttaggtag ccaagctgaa accatggcat ctgactcgcc
     1381 atttgaaaca gatttccaca tgattgaatt atctaatggc gtcatcgtta catcatagcc
     1441 catttgtttc aatacttcac cgactacatt tgttgaagca acttctgtat cccattcaac
     1501 ataagataag ttgatacgtt ttgtttcttt ggcagatgaa aaactcccta taccaatcgc
     1561 acctaagatc actactacta cagcaccaat gatcagtcct tgacgttttt tacttttctg
     1621 tgttgttgct cctgcagctt ttttattgtt tggctggttc aaatgctgtg taaaacggtc
     1681 aatgatgatt gctaagataa ctaatgcaac cccgttgaca aatccattcc cgacttgtgc
     1741 tctttgcaat gctgataata cgccgcgtcc taagccgggt gcaccgatca tagaggcaat
     1801 aacgaccatt gaaagtgaca gcattgttgt ttgattgatc cctgccatga tcgtactttt
     1861 agctaaaggc aattctagtt tgaatagttt ttgacgactt gtgctcccga atgaatcaga
     1921 agcttctact aattctttag gaacttgtcg aatccctaaa ttcgtaaaac gaacggttgg
     1981 tggcagagca aagatgactg aggcaaatac ccctggaacc atcccgatac cgaaaaatgc
     2041 aactgctgga atcaaataaa cgaatcctgg cattgtctgc ataaagtcaa ggatcggttt
     2101 gataatactt tgggctttac tgctttttgc catcaagatc cctaatggta ccccaatgat
     2161 gatcgagatc acactagata aaagaacaag tgtgacagta ttcatcaaat cattccatag
     2221 accttggtta taaataaacc atagaccgat taatgtgaac aacgtaagtc ctggacgttt
     2281 cttagaaata aagaaagctg ctaccgtcaa taacaagata aacaaaggag ctggaatcac
     2341 taacagtaaa tttgtaatcc ccgacatcac tgcctgtcca atcgtttgta aaaatgaaaa
     2401 taggccagaa aaagttgtcg taaaccattc tgtgatattt tctacccagt ttgccactgg
     2461 taattgatag ttcaatagat tattcatgtt cactcacctc gcttgtttct gctaatgctt
     2521 caatcacact acctcggatg acgacacctt ttaattttcc atcctctaca actgcaagtg
     2581 gagtcggtga gtcataaata atattgaaaa tatcacttac caccatgtct ttcccaatca
     2641 ccgtcacatt ttcatctagg aagtcgatca atggacgttt ttgcttccta gcttctaacg
     2701 cttgatctgc agtgatgatc cctttcaggt gtctctttct gtcaacagcc atcagcatgc
     2761 tgacttcttc attacgcatc cttgtcaatg caacgtttgg tccatcagat tcgatattcg
     2821 tcgtcaatgc aggtaccatg atgttttgag ccgtaagcac tttggaacga tcgacttctt
     2881 ccacaaattc acgtacataa tcatttgctg gattggtcaa tatttcttca cctgttccga
     2941 tctgcatgat ttcgccgtct ttcatcaagg cgattctgtc cccaatccgt aaagcttcat
     3001 tcaaatcatg ggtaatgaaa ataatcgttt tttgaacatt ggcttgcagg tccagtaatt
     3061 cgtcttgcat ttctcgccgg atcagcggat caagagccga gaacgcttcg tccatcagca
     3121 agatctcagg atcatttgct aaagctctgg ctaggccaac ccgttgttgc atcccaccag
     3181 ataactgact aggatattgg tctttaaatg aaagcaaact agaattttct aatgcttttt
     3241 ctgctttttc ttgtcgttct tctttaggta caccacggac ttctaacccg tattctgtat
     3301 tttccaagat cgttcgatgt ggaaacagac cgaagttttg gaaaaccata ttgattttat
     3361 gacgacggac ttctcgcaat tcttctttgc ttaacttcga tacatcttct ccatcaatat
     3421 agatactgcc cgaagttggc tcaatcagac gattcaatag acggatcaat gtggatttcc
     3481 cactcccgga aagccccatg atcacgaaga tttctccttc ttttacgtca aaattcacgt
     3541 catacacacc aaccgttgca ccggttttct ttaaaatctc cgttttcggc tggtgatcat
     3601 tcatcatatc taaagcggct tgtgtctttt taccaaatat ctttgttaaa tgttttactt
     3661 ctacttttac caaacaaatt ctcctttttt atgtaaattc atttttcttt ctgaaaaaag
     3721 tgaccacact atgttaacat catgtagtca ctttgtcaaa aatgaaagaa atttgcttgt
     3781 ccaaactgaa aaaaacttgg ctaaatcttt gtaaataaaa ggtttagcca agttaatatt
     3841 tttttaatat ttcacacaat cattctgcaa gctgatgctc cgggtaaaaa aagtttgtca
     3901 tacgctgtag tgtatattca tttccaataa aatgaacgat gtcccctgcc gtaaatttag
     3961 cataggggcc aggtgaaaca agcagttctt cattatgaga aattgcgata actgtggcgc
     4021 cagtcgcctg ccagatattc aactcgctaa ttgaacggtc cagatgcatt gctttttctg
     4081 ataaagataa ttcaaacgga agtaaaggat tcatcttatg tattcgcttc gtttgattga
     4141 ccagctgatc caataattga gaaaaatgat tcagctcatc ttgttgcttc tccacacttg
     4201 ccatgatttc tgcttttgta tcttggatgg attgtacatc ttgatattgc aataggaaat
     4261 cttttgcttt ttccttcgaa gcaacaaatg ccccacttcc atgccgtact tccatgattc
     4321 caagatctac cagcacattg atagccttgc gggtagtctc aggagaagca ttgtacgtac
     4381 tggcaagtgt tgagcgggca tggatcttct cacccacttt atatcggttt tcaacgatac
     4441 gttcggctaa atcaacagca atctgctggt agcgcgggcg gacgattttt ttctttccag
     4501 acattttctt tcctctttct ttttttactt tccctcatct tactatgctc tagcaaaata
     4561 agcaaaaaag gggagaatag cctcttgcaa cgactgatca tcgcttgatc tgttcctttt
     4621 ttactgggca agctgtttga cagtcatcac aattcttacc ggattttaaa cgagtataga
     4681 caattgcgcc tgcacttcca aagattaaca cacttaataa gaatgtcgcc atcctattcc
     4741 tctccttcta atgacaatat agtataaaac tggttcttgg attttggctg acggaacaaa
     4801 acataaacga gtcctatcat cagtaaaata gcaagatacg tccctaacgc tacctgtcca
     4861 ccctccaata agtgtcccaa ctgataaatc acaaaactaa ctaaataagc taaaccgcat
     4921 tgatagccta tggcgatcca agtccatttc ttggcattca tttcccgatg gatagcccca
     4981 attgccgcaa aacaaggcgc acaaagtaaa ttgaaggcta acaatgaata agctgctgcg
     5041 ggagtatatg tgtgttgtag cacttgccag atttctctgc cattttcgga tacttccgca
     5101 tgaccaaaca aaataccaaa tgtgccaata atattttctt tagcgaccaa tcctgtaatc
     5161 gctgcgactg ttccttgcca gtttccccaa ccaagcggct gaaaaacaac tgccaggatt
     5221 cgcccgaaaa aggctaagat actttggtct tcagaaacag gttgagcata aaaattataa
     5281 gaagagctga accagatcac gatactagaa acaaagataa tcgttcctgc ttttttaaca
     5341 aaagacttgc tgcggtcata ggtttgtctt aggaccgctg accattgagg aaaatgatat
     5401 gcgggcaatt ccatgataaa aggagctgta tctccagcaa acaaacgtgt ttttttcaag
     5461 ctgattccag agaaaataat tgcagtcata ccaagaaaat aggcagaagg agctacccaa
     5521 gattgatgag gaaaaaaggc ccctgctact aaggcaataa tcggcaactt tgcagaacaa
     5581 ggcatgaagg ttgtgaccat gatcgtcaaa cgacgatctt gctcgttttc aatcgtgcga
     5641 ctggccatga cgcctggcac tccacatcct gtagcaatca gcataggaat gaaggatttt
     5701 cctgaaagac cgaatttcct gaaaagtcga tccatgacaa aagcgatcct cgccatatat
     5761 ccgcagtctt ccagaaagct caagcataaa aacaatataa tcaattgcgg tagaaatcct
     5821 aacactgctc ccacgcctgc gatgatgccg ttcaagatca gctcctgcat ccatcccgct
     5881 acttgccatt cagctaacaa tctgccaaca tgttctggta accatgtacc aaacaatgtg
     5941 tcattgatcc aatctgtccc cattgttcct actgtttgaa tagccagata atagatcagc
     6001 cacatcacaa atgcgaagat cggcaaggct aaccaacgat tcgttgcaat ctgatcgatt
     6061 ttgtcactca tcgataattg gaaagaatca tttgacacaa cacagagtgt acatagttgg
     6121 gtaataaatt cataacgttc attgaccaga atcgtctcac tatcgtcgtc caatagtttc
     6181 tctgttaact ggatcagttg ctcgatctct ttttgctgag aaactgctat ctcgtaatcc
     6241 tctcttacct tctgatctcg ttcaaaatat ttcattgcat accagcgttt cttgccgctt
     6301 tgttctccta gtacatcttc aatttcatgt aaagctgctt ctaaacgtgg atcatatgta
     6361 cagggaacag gaatagaagg ccgctttttt gcagactcct gaatcttttc gattagtttt
     6421 tcgattcctt gctttttcaa tacgctgatt ggtaaaactg gtacaccaag accataggaa
     6481 agcttttcta gattgatttt ttttccttct tttttgatga catccatcat attcagacca
     6541 atgatcatag gaatgtctaa atccaataac tgcgtagtta aataaagatt tcgttctaaa
     6601 ttggtagcat caataatgtt gatgatcagt tcaggctgtt cctgaaccaa ataatctctt
     6661 gcaatcactt cttctggtgt ataaggagac aaagaataga tgccgggtag gtcctgaata
     6721 tgaatgttcg gatttttttt caacgatcct tctttttttt ctactgttac gcccggccaa
     6781 ttccctacat attgattcga accagtcaag agattgaaca agctagtttt cccgctgttt
     6841 ggatttccga ctaacgcgat attcattctt tttcctccct ttgtatcaag attagttcgg
     6901 cctctgactt tcgtaacgtc agttcatacc ctcgcactgt cagttcgatt ggatctccca
     6961 gaggggctag ttttcggata actattttta catttcgcgt caatcccata tccattaacc
     7021 gtcgcttcac tgcgccttgt ccgtggattg ctacgacgat cccagtctct cctgctttta
     7081 attgatcaag agaagtccag ctttcagagg aagcagtctt tttattgaca aagatttgac
     7141 ctagtatttc ccgacttact gccactcgat gactttttac cagtaaaatg gcattgttgc
     7201 ctgataaatt gacgacgacg attttacttc cggcaacgat cccgatattt tgcaaatggc
     7261 gttttgtttt ttcttctgtt tcgattcgtt cgacttgata aacgaaattc tgctttgcct
     7321 gcgctaaggt ctgcatattg attcctctct tgtgaaataa atcatgtatt aaaatcattc
     7381 attatatgtt ctaattttct tacgtgttac gcaaataaat gagaatcatt ctcacataga
     7441 atactctcgg taattgagaa tgtcaattat acttgtgata ttatgagcga atctttagta
     7501 ttgatagata aaaatgagaa aaaaatattt cttcatagtt ttccacaatt ttttctctat
     7561 taaatttgct attttcccac acgatacttg ttttcagctc ttttttcaaa aacacaaaac
     7621 ttagtattcc acagtttcca caacacaata tgtagtgttt gttgtttgac ttttttacta
     7681 agagttttat actatctatt atagataata agaatgtgtt agaggaggca ctcaccatga
     7741 acgtaaaaat cttttctaaa aataattgta tgcaatgtaa gatggtcaaa cggtttttaa
     7801 cagaaaatca aattgctttt gaagaagtca atatcgatga acagcctgaa gcagtagact
     7861 ggttgaaagc acaaggattc caaagtgttc ctgtcattac ttctgatgca gaaacagtta
     7921 tcggattccg tcctgatcag ttgcgtaaac ttgccagcta acatgactaa aagaatcaaa
     7981 acgtgataca tggatttgaa gggcttgaga cagcaccagt ttttgtcgca aacttccaaa
     8041 tcctttttta aagcttaaaa acaatgcaat gatttgcaat caagcatcat caaatacgaa
     8101 atgaaggttg ggcgtacgta tgagtcttaa aaatttacaa gatgtcagtt atttcaagct
     8161 gaataatgaa atcaatcggc cagtcaatgg tcaaatccct ttgaataagg ataaagaagc
     8221 tttagttgcc ttttttgagg aaaatgtcaa accaaatacg atgacttttc tatctattat
     8281 ggaaaaaatc aattacttga tcgatcaaga atatatagaa gcagaattca ttcaattgta
     8341 ttcaccatca tttattgaaa agctatatca atttttggac gagcaacatt tttctttcaa
     8401 atcttttatg gctgcttaca aattttattc tcaatatgcg ttgaaaacca acgacggttc
     8461 cgcttatctg gaaacttatg aagatcgagt agccttcaat gcgctttact ttgcgaacgg
     8521 ggatgaagaa ttagcacttg ctcttgcaga cgaaatgatc catcaacgat atcagccagc
     8581 tacaccttct ttcttgaatg ctggacgtaa acgtcggggc gaattggtgt cttgtttctt
     8641 gactcaagtc actgacgata tgaactctat cgggcgctca atcaactctg ctttgcaatt
     8701 gtcccgtatt ggtggcggcg tagggattac tttatcaaat cttcgtgaag ccggcgctcc
     8761 tatcaaagga tatgagggtg ctgcaagtgg tgtcgttcca gtcatgaaat tattcgaaga
     8821 tagtttcagc tattctaatc aattaggtca gcgtcaagga gctggcgtgg tttatttgaa
     8881 cgttttccat ccagacatta ttgctttcct ttcagcaaaa aaagaaaatg cagatgaaaa
     8941 gattcgcgta aaaactcttt ctcttggcgt gatcgtacct gataaatttt atgaattgac
     9001 acgtaaaaac gaagatatgt atttatttag tccatatagt gtcgaaaaag aatatggtgt
     9061 cccattctct tatgtaaata ttacagctga gtatgatcat ctagttgcaa atccaaacat
     9121 tcgcaaacaa aaaatcaaag cgcgtgatct tgaaaatgaa atctcaaaat tacaacaaga
     9181 atctggctat ccttacgtaa tcaatattga tacagcgaac cgcgagaatc caatcgatgg
     9241 caagatcatc atgagtaatt tatgttcaga gattttacaa gttcaaacgc cttctgtgat
     9301 taacggcaaa caggaatatg aagtattagg aacggatatc tcatgtaact taggctcgac
     9361 aaatatcgtg aatttgatgc aaagccctaa ctttggtcaa tctgtgcgta cgatgactcg
     9421 tgcattgaca tttattacag atgcatctga tatcgatgtc gtaccaccga tccaaaacgg
     9481 aaataagctg aatcatacga ttggattagg tgccatgggc ttacacactt atcttgcaaa
     9541 agaacaaatg gaatatggct cagaggattc attagacttt acaaatattt acttcatgct
     9601 gttgaattat tggacacttg ttgaaagcaa caatatcgct cgtgaaagaa aacaagtttt
     9661 ccataatttt gaaaaatcag cttatgctga cggcacttat ttcgaaaaat acgtaactgg
     9721 agaattccag ccaaaatcag aaaaagtcaa agcattgttt gaaggcattt ttatcccaac
     9781 tgctgaagat tggaatgctt tgaaacaagc agtaatgaaa gatggactgt atcatcaaaa
     9841 tcgcttggca gtagcaccaa atggctcaat ttcatatatc aacgatacga gtgcaagtat
     9901 tcatcctatc actcgcatga tcgaagaacg ccaagagaag aaaatcggta aaatttatta
     9961 cccagcgcct tatctatcca atgagacgat tccgtattac acttctgctt atgatatgga
    10021 catgcgtaaa gtaatcgatg tttatgcaat ggcacaacaa cacgtcgatc aaggcatgag
    10081 tttgacttta ttcatgcgtt ctgaaatccc agaaggcatt tatgaatgga agacaacaac
    10141 gaagcaaacg acacgtgatt tgaatatttt aagacattac gctttccaca aaggaatcaa
    10201 atccatttat tacgtacgta cctttactga tgatgcagaa gaaatcggaa gcaatcaatg
    10261 tgaaagctgc gtgatctaat atcatagata gattcgctta ttcatatttt aattaaagga
    10321 gcattctcat gtcagaaaca tattatgaag caataaactg gaatgaaatt gaagatatca
    10381 ttgataaatc cacttgggag aagctgacag agcaattttg gctagataca cgtatcccac
    10441 tttcaaatga cctagatgat tggcgtacat tgtctcaatt ggaaaaagat acagtaggac
    10501 atgtatttgg cggtttgaca ctgctagata ctgtccaatc tgaaagtggc atggatcagt
    10561 tgcgtaaaga tgtccgcact ccccatgaag aagccgtttt gaacaatatt caattcatgg
    10621 aatccgttca tgccaaaagt tattcttcta tttttagtac actgaatacg aaaaaagaaa
    10681 tcgaagaaat ttttgactgg acaaatacga atccttatct gcaaaaaaaa gctgagcgta
    10741 tcaatgaaat ctacaaacac ggtacaccgc tagaaaagaa aattgccagc gtctttttag
    10801 aaacattctt gttctattca ggtttttata ctcctcttta ttatttagga aacaacaaat
    10861 tggctaacgt agcagagatc atcaaactaa tcatccgaga tgaatctgta catggaacct
    10921 acatcggtta caaattccaa ttaggattca acgagttacc tgaagcagaa caagaaacgt
    10981 taaaagactg gatgtacaat cttctttatg agctttacga aaacgaagaa cgttatacag
    11041 aagaattata cgatccaatc ggctggacag aagaagtcaa gacattccta cgctataatg
    11101 ccaacaaagc attgatgaac ctagggatgg atccactctt tccagatact gccaatgatg
    11161 tcaacccaat cgtaatgaac gggatttcaa caggcacaag caaccatgac ttcttctcac
    11221 aagtcggaaa cggctatttg ttaggtcatg tagaagcgat gaaagacgac gattatttga
    11281 ttggattgga ataaggattt attttaattc aaaaattttt cgaaaaataa aaagagttta
    11341 gcgtacagat attttaaatg tacactgaac tcttttttat gcttattcac ttgtttcttc
    11401 cagcactttt ggactgtcta acttttccga aacatgttcc attcttctca ataaatagat
    11461 tttccggata tttaatatta tcgtcttaat cactgcatag acaggtatgc aaatcagcat
    11521 gcctaatatt cctgcgacac ttcctgctcc aatcaatacc aagatgatcg tcaaaggatg
    11581 gatattcatt gatttcccaa ataacaacgg cttgatcaaa tttccatcta attgttggat
    11641 cactaaaatc gacaacgcca tatacaaagc ttgaaatgga gagataaaca aaccgacaat
    11701 gattgctggt accgctccaa taaaagggcc gacatacggg ataatattcg tgattccgca
    11761 aatgaccgca agcaacaagc tataaggctg atcgaatatt ctcattgcca aaaagctcat
    11821 tacaccaata atcaaagcat ctaagatcgt actgctgata taggcagata atgtttcgtt
    11881 taattctttt accgtttggc gtaactcttt acgaatcgct ttcggaaaga agtgagacaa
    11941 cgcatcaata aatttgtgcc catccttgaa cataaatagc aaaataaatg gaacggtaaa
    12001 taacaaaata aaaaattgca tcataaatga aatgattttt gagacacttg cagataaact
    12061 gactaatatg atattgaaca aattactaag agataaattt gctgatgcta attgttcttc
    12121 caaattgaaa tttttaaact cttcccgctg cgccaattca tttaaccatt tgcttgtttc
    12181 atctgcatac attggcaagc tctgggtcaa ttgaattgtc tgttccatta actgaggcac
    12241 tacattcatg acagttaaaa caactaaaat gattacgacc aaaaacgtca ataaaaaacc
    12301 gaacactctc gggatccgat gcttttcgag aaaaacaacg attggatcga acatataata
    12361 gataaaacca gcaacaagca atggtaaaaa aactgccgaa agcattttca atattggact
    12421 aaaaatattc ggcatttgta aaataaagta cacgccgatg atcgtgagta ctagctccac
    12481 tgtccagaaa aataattttg attgtttaaa acgtgattgc atacatctcc tccaaggtcc
    12541 tttgatactt ctattctatc atttaacaaa gagttacgcg ctgagatttt catttgctta
    12601 aaaaaaacaa aaaaaataaa catattttaa tgagtagacg agtacttaaa caaaaacacg
    12661 gtttggagta gtgacaaaaa ttatactgca gtcccttttt ccaaataaac ggtgttcaaa
    12721 agcttgcatc ttcgtaataa gcccagccaa acgaaaaata taaggaacta tttttatttg
    12781 gctgggctta ttacttgatg taggacatct attttacaac ctcagatcat ttattgcgca
    12841 atactgacta aatgcaactt tgtgatattt ttgtgtacgg acaactcctc gatcacatcg
    12901 gcataagtga gcccttttgg aagatcaatc gtatagatat ttttgtacac tcggtagtca
    12961 tcaacgaatt ttacgtcaaa attcacatct tcgattacga tatttttctc ttcaaaataa
    13021 tcggtaagaa aatctttggt ttcttttcta tggataaatt ggatttctaa ctttttagtc
    13081 gtaggtacat ggatcacgcg tttcactact gtgagtgcaa tagcaatccc gataaaactg
    13141 atgatcgcaa tggaatagta acccatgccg atggcgatcc ctaatccagc aattgcccat
    13201 aaagaagcgg cagtcgtaag tcccgtcacc gattgtttcg tgacgatgat cgttcccgcg
    13261 cctaagaaac cgacaccact caccacttga gcaatcagcc ttgcttcatc tgaacgaatc
    13321 gttccagcaa gctgtggata ctctaaagca tctcttaatg caccactagc gatctcaact
    13381 tggatcaatg caatgataca tgctcccata caaactaaaa tatgcgtacg catacctgct
    13441 ggacgatttt tatattgtcg ttcaaaaccg attgctccgc caaatagcat agcgatccct
    13501 aaacgtaaaa taatctctgg aattgtcaat accatatcat tcatctaaac accctccagt
    13561 ccaatatatc atgtctgaaa ggagcagaca aaaaaagtgc aatttttacc tcttacgaaa
    13621 aaaggactgt gacaaaattt ttgtcatagt cctttttatg aataaacggt gttcaatcag
    13681 ctgaccctcg gtattactca acaaacggca aaatatgggg agctattttt cctttgtctt
    13741 ctctaatact caggtcaaaa cgctgatttc acaacctctt tagcctacta ttgaaaatta
    13801 caacttactt gctgcttctt catcgatgat cacaacaaca ttgtcgtgat tttgcaatac
    13861 acttgctggc aaatgattcg ttacaggtcc ttcaatcatc cctttgattg catcagcttt
    13921 gctttcgcca aatgccatca agacgatttc tttacttttc ataattgaac cgattcccat
    13981 tgaaacagct tttgttggta catcttctgc tttatcgaag aatcgtttgt ttgcattgat
    14041 tgttgattct gttaagtcaa ctactgaagt cgttccgtca aatgaagcac caggttcatt
    14101 gaaaccgata tgtccatttt gcccgattcc taagatttgg atatcgattg gatgtgcatc
    14161 gatgatttga tcatactttt tgcatgctgc ttccagatct tctgcttttc catctggtac
    14221 aaacgtttct ttgaatggtt ttttatcaaa taattggaca tccatgaaat gacggtagct
    14281 ttgttcatct gaaccgccta gtccaacgta ctcatctaag tttacagaag tcatttcact
    14341 gaaatccaaa tcgcttgaag tcatttcttt atataaagta actggtgtgc ttcctgttgc
    14401 caatcctaat acttttgcac ctttgttcat accttctttg atgatttcaa atgctttttt
    14461 tccgccttct tcagcgtttt ttacacgaat gatttccata gtgattgctc ctttatattt
    14521 tggtatagcc caattatagc attctttttt tctttttaca ataattagta tagaccaaat
    14581 tgcatttttt tcattttctt gacaataaat aggaatccgt gttaggtttc ataagatggt
    14641 tcaatcaaac aatccatgtt gcatgaaaac caagcaagtg attcactgtg gacgctttat
    14701 gtctgcagtt tttttatgaa aaaggagtta ttatgagtat actgacatta aacaacatta
    14761 cccagcaatt tggcgacaaa atcctctatg aaggtgtcga tctgcaatta aatgctggcg
    14821 aacatcttgg gctgattgga caaaacggag ccggtaaaag tacattgatt aaaatcatca
    14881 ctggtgagat cttaccagat gacggacaga tccattggca aaaaaatatt cacaaaggtt
    14941 acctcgatca atatgtggaa gtcgatgaaa cattaacaat cgaagaattt ctaaaaactg
    15001 cgtacgcaaa agaatacgaa aaggaagaaa aaattgcttt tctttaccaa acatatagcg
    15061 agaccttcga tgattccttg ctggaaaaag ctgggaaact ccaaacggaa ttagaccaag
    15121 gagtgtttta tcaaatcgac accttagttg ctgagatgag cagcgggttg gggatcgatg
    15181 tcttaggttt agattcactg ttgaaaaatc taagtggtgg acaacgttca aaggtgattt
    15241 tagcaaaact acttttagaa aacccagatg ttctgatctt agatgaacca accaatcact
    15301 tagatgatca gcatatccaa tggctgacgc agtttcttca ggattttgac ggtgcgtata
    15361 tcgtgatttc ccatgaccaa gaatttcttg atcagatcac cacccatatc gcagacatcg
    15421 agtttggaaa gattactaag tatactggcc atctaaaaca agcattgaaa caaaaggaac
    15481 aaaatcgcga aagctatttg cgccaatatc atgctcaaca aaaacaaatc gaaaagaccg
    15541 aagcttatat tcgaaaatac aaagccggtt cccgatcaac gatggcaaaa agccgacaaa
    15601 aacaattaga taaaatcgaa cggctgacgc ctccagcttc agcaagtaaa gctgtctttg
    15661 attttccatt ctcgcctatt gtcacgacat tagcagtgga aacaactgat ttagtcatcg
    15721 gatatgatcg accgctactt gcacccatca atttgaccat ccgctttggt gaaaatattg
    15781 ccattcgagg cttcaacggg attggaaaat ctactttatt aaaaacactg atcggtgaga
    15841 ttgaaaaaat aagtggcgat ttccacttcc cagataacac aaaaatcaat tacttttcac
    15901 aagatctgta ctgggaaaat ccattagaaa caccactaca atatttaagc agtcaatttc
    15961 caaaagcgac tatcaaagaa ttacgtcgcc aactagctaa agcagggtta gttaatcaat
    16021 tagcaagtga acctctcact acattaagtg gtggggaaca aactaaggtg aaacttgcac
    16081 agttgacaat gaaccaaggt aatttactga ttctcgatga accgacgaac catatcgatc
    16141 aagaaacgaa agaaagctta caagacggga tacagaaatt tccaggaaca gtaatcatcg
    16201 tctctcatga acaagaattt tatcaagatc ttgtgcaacg agtcattgag attgaaccaa
    16261 aataaacgtt tgattgaata gttgaaaaaa aggagctgtg acaaaagttt tgtcacaact
    16321 ccttcttctg aataaatggt ggccaattag ctgaccttcg gtattagctc aaaaaacggc
    16381 aaaatatgag gagctatttt tatttggcta ttcttattac ttgatgcaga acagcttttc
    16441 acaacctctt ttcgtctatt ttttattttc gagatttctc tttcctttaa aaacaactgt
    16501 ttgaaagaag aacgcacatc cttgaaaaac aagcccgcta accgttacac ctaaccagcc
    16561 atactgctgc cacattgtcg tccctagcaa tgaaccagcc gcacctccaa taaagtacat
    16621 aaacataaat acagtattat ttcggttgct tgctgcttca cctagcccct gtactcgtgt
    16681 ttgattggcg acttgaccaa attgattccc gacgtctaat aaaataatag ctaaaagcaa
    16741 aatggccaaa tggcttccgc caaccaataa agcaataaag cttattgttt gcataacaag
    16801 tcccatatac acgatttttc tttcagaata agaatctgcc agtcgtccca cgataggtgc
    16861 agcaactgct ccagacaaac caaaaatcgc taatatccct gcttcgaatg ttccccaatt
    16921 gtaggcggga ctgctgatat aaaaaatcaa cgtagaccaa aagatcgaaa atgttccaaa
    16981 catgaaaaat ccactgactg ccgcttctct taatagacgt tgagaagcaa ctaaatgcgg
    17041 caaactttta agtgaatcaa ggtatgaaac agctgtacta ctttgctgga cagaacgcgg
    17101 cattttccag taaagcagaa gtgtaagaat tccgactgca cataaagcaa ataaatagat
    17161 catccgccaa gaaaaaagac tggcaacaat accagatacc gtccgagaaa gcaaaatccc
    17221 cacgagtaaa ccgctaagca atgtacccat gaccttccct cttgcttttg gtcccgctag
    17281 taccgcaccg taaggaatga tgatttgcgg cacgatcgaa agtaatccta ttaaaaaaga
    17341 agcgcatgca aataacgtaa acgaaggcgc aaaaaaagcg gccaacagag agacggcaga
    17401 taacgctgcc attcgaatga tcaattttgg acgatccacc acgtccccta aaggaactaa
    17461 aaacagtaac cctaacgcat agcctaattg ggtcaacatc gtcaatatcc cgactgcact
    17521 tgtgctaaca gataaactag ctgctacttt tgttccaatc ggctggatgt aatacatatt
    17581 ggcaacaaca acgccacaag tgattgataa tagtaaaata agcgaagttg ttaaaggttt
    17641 tttttcatta ctcttcattg atttccccca tttcctatct tagtttacaa cttatggaaa
    17701 agattggaaa tagaaaaata caactattcg ccacacttat tatttgtgct tttgttttcc
    17761 ttgttttttc ttgcgatctt tataaatgaa gacaactaac cctactagca cagtaacact
    17821 tgcaaccaac gtgactgcag ttttgttata tccgtgaaac agagcttctc caccacacgc
    17881 atacaacaca gacgaaggga tgactccaat cacgatcgac aatatgattt gctgtagagg
    17941 caatttcatc gcatctgcag caaaattgac catagaagat ggaataaccg gtatcatata
    18001 gcctaacatt acacctattt ttggatgttt catttgtcgg attgcttgca cccaatgatt
    18061 cgtttcggtt ttcttatcta aaaattttaa gcgatgcata aggaaaattg cagtgatgtt
    18121 accaagagca ttacccaaaa tgttgatgat cgcacctgtc agtggtccaa agctcaaacc
    18181 agcaatgact ccaactactg aagtaggaat acctggaaca gcacacatca ccgctgtcaa
    18241 tacgatcaag agtatcgatg caaaagtccc atgcgaacga atatgtgcga gtagctctgc
    18301 cttactcgct ctcggattta aaaataattg gatgtctgtc tgatattcta aatacaaccg
    18361 atagcccact accagtatca gaatgattcc caacgagatc aatatcaatc ggattatttt
    18421 ctttttcata tttcctcctg aaaaaaatct atattcatta aataatagtt taacataaaa
    18481 acaaaaaagc accgaaatcc aacataggat ctcagtgctt ttaaatagta aaaattattt
    18541 aacagttaca gatgcgccaa cttcttcaag tttagctttc aattcttcag cttcttcttt
    18601 agatacgcct tctttaactg gtgcaggagc gccatcaact acagctttag cttctttcaa
    18661 gcctaaacca gttgcttcac gaactgcttt gataacttta actttttggt ctccagctgc
    18721 agttaattct acagtgaatt ctgtttgttc ttcagcagca gcagcgccac cagcagcagc
    18781 tacagctaca ggagcagcag cagatacgcc aaattcttct tcaatagctt taactaggtc
    18841 gttaagttct aggatagttg cttcttttaa ctcagcaacg atgttttcaa tgttcaatgc
    18901 cattataatt tcctccgttt aattgttctt ttttatttaa tgctttatgc ggcaattaag
    18961 ctgcatctcc atcttctttg tctgccactg ctttgacagc gtaagccacg ttgcggactg
    19021 gcgcttgtag tacagatagc aacatagata gaagtccttc gcgatttggc aattttgcca
    19081 atgctgtgat ttcttccaat gaagagactt taccttcgat gataccgcct ttgatttcta
    19141 atgcttttgc ttctttagca aattcgtcca tgattttcgc tggtgcgact acatcttcgt
    19201 tactgaatgc aacagctgta ggtccagtga atacttcgtc catgccttca aggccagctt
    19261 ttttagctgc acgtgaaaga atagaatttt tgataacttt catttctacg ttagcatcac
    19321 gaagttgttt acgtaaacgt gttacttcat caactgttaa tccgcggtag tcaacgacta
    19381 ctactgatgc agctgctgta aatttttcgc ttacttcatc aacgattgct gctttttttg
    19441 cgataattgc ttcactcatt tttgagtttc acctcctgaa ttttgatgga agagtttttt
    19501 gcactgaaaa ggcaagtcac ttttatagtt actttgctca accagtatta ttcatcacct
    19561 attcacttcg ttcatagtga ttctactcgc tttgctcgaa aggaaactcc tttcgctttg
    19621 ctcaaccagt attgttcatc atctcttcac ttcgttcata gtgattcaca ataaaaaact
    19681 ctatgccacc gcagacatag agggactatt gaatatattc aataaacgtc ctcggtagga
    19741 aattaaggct tgatgccacc tactgtcttc ggtacaagtt aattattaac ctcaactagc
    19801 ttagcatgct aaactagttg agtcaagaat tatttttcag ttggatcaat caacattcta
    19861 atatttaatt agaaagaagc ttggtcaaca tggataccag gtccaaatgt tgttgtgatc
    19921 gttacatttt tcatgtattg acctttagct gctgatggtt tagcttttag caatacatca
    19981 tggattgctg caaagttttc aactaatttt tcatcgtcaa atgaaacttt tccgattggt
    20041 acatggatat ttccagcttt gtccacacgg taagttactt taccagcttt cacttcgttt
    20101 actgcttttg ttacgtccat tgtaactgta ccagttttag ggtttggcat taagcctttt
    20161 ggtcctaata ctcgtcctag acgacctaca gtagccatca tatcaggtgt tgcaacaact
    20221 acatcaaagt caaaccatcc gttttggatt ttttgaacca tgtcgtcgtc acctacgaaa
    20281 tctgcaccag ctgcttcagc ttcttttgct ttgtctcctt tagcaaaaac taaaacagtt
    20341 tgtgttttac cagttccgtt tggtaataca acagcaccac ggatttgttg gtctgctttt
    20401 ttagggtcta cgttcaaacg gtatgcaact tcaactgttg catcaaattt tgcaatgttt
    20461 gtttcttttg ctaaagctac tgcttcggca acaggataaa ctttacttga atcaactttt
    20521 tttaatgcat cttgcatttt tttgctcttt ttagccattt tggttcctcc ttgattgtgg
    20581 ttataacggt tgtacctccc acgtgttcta tatctttcaa tatagagcca actgagaagc
    20641 tgctgtctta gggtgtatag attattctac agtgatcccc atgcttcgtg cagttccttc
    20701 aaccatgcgc attgctgctt caacgttagc tgcgtttagg tcttccattt ttaattcagc
    20761 gatttctctt acttgatcgc tagaaacttt cgcaacttta tttttgtttg gttcgcctga
    20821 acctttttcg attttagctg cttttttcaa tagaacagca gctggcggtg tttttgtaac
    20881 gaatgtgaat gaacggtctt cgtatacaga aataacaacc ggaatgatca aacctgcttg
    20941 atcagctgta cgagcgttga attcttttgt gaatcccatg atattgatac ccgcttgacc
    21001 tagtgcagga cctactggtg gagctggagt tgctttacct gcaggaattt gcaatttaac
    21061 gattttttct actttctttg ccacgagaca tacctcctta agtccgtgat gtggttaatt
    21121 ggagatgcat atttctcctc ccacgtttta tctgatctga aaaaatccag acaaataatg
    21181 tgcaaaacaa tgcacactgg tacagtatag caaatttatt tgttttttca agattttttt
    21241 ctgctatttt tacattttgc ttgaataaac gctaaattta ttctaaaaaa acaacaattt
    21301 ttcgttctca tttcttcttt tatgttacac ttgcgctagc atggttcaac agatgaaagc
    21361 aaacaataac acggtttttt agacccttgt acaaagattc ctacataaca aaatgaggtg
    21421 gagaaaatga aagatttaag gtatagaagt gtctttgata ttattggacc tgtgatgatt
    21481 ggtccaagta gctctcacac tgccggagct gctagaatcg ggaaaatcat acgtagtata
    21541 tttggcgaac agcctgattc tgtagatatt tatctatatg aatcatttgc aaaaacctat
    21601 cgggggcacg gaacagatat tgcattagtt ggcggcctgt tagggatgga acccgatgat
    21661 gaacgtttag ctgattcttt gaaattggca tatgaagccg gtatggaagt cttgtttgtt
    21721 cctaagagtg aaaaagccga acatccaaac tctgtaaaga tgcttctaaa aaaaggaaca
    21781 cgaaagcttt cagtcactgg catttcgatc ggcggtggca atatccagat ttctgaattg
    21841 aatggattca aaatttcttt aagcatgggt actcctacct tgatcgttgt ccaccaagat
    21901 gttccaggta tgattgctaa agtgactagt atactttctg agaccaatac gaatatcggc
    21961 actatgacag tgacacggga atcaaaaggt gaaaatgcca ttatgataat tgaagtagat
    22021 gatcctcaag tagaagaaac ggtaaaaaga ctcaaacagc tgccaaatat cgacagcgta
    22081 aattatttcg attaaggagc taaaaaaatg tttttatcga ttgaagaatt agtagatcaa
    22141 gcaaaagctt atccaagtgt agcagaattg atgattgcag ttgaaatgga aatgagtggc
    22201 cgttcccgta gtcacatcat cgagatcatg gaaaaaaacc tctcagtaat ggaacaatca
    22261 atcaacgagg gaaaagaagg tgttacctcc gtcacaggaa ttaccggtgg tgatgcaaaa
    22321 aaattagatg attatttaaa tgaggcagac tttttaagtg gagaaacaat cttaaaagct
    22381 gtacgcaatg ctgtagctgt taatgaagtc aatgcaaaaa tggggttgat ttgtgctaca
    22441 ccgactgccg gaagcgcggg tgttgttcct ggtgtgctga tggctgtccg agatcggctt
    22501 gatttgacac atgaacagca attggaattc ttatttaccg ctggcgcttt cgggttagtc
    22561 atcgcaaaca acgcttctat cagtggtgca gaagggggat gtcaagcaga agttggttct
    22621 gcaagtgcaa tggcagcagc agctttggtt tgtgcaaaaa atgggactcc tcatcaagca
    22681 gcacaagcag tagccattac attgaaaaat atgatgggac tgatttgcga tcccgttgca
    22741 ggcttagttg aagtcccgtg tgtcaaacgt aatgctttag gctcttctca agcttttatc
    22801 tctgctgata tggcattagc gggtatcgaa agtgtcattc cgccggatga agtcgttgct
    22861 gcaatgtacc aagtcggacg tcaaatgccg tcgattttca aagaaacagc agaaggtggc
    22921 ttagctgtta cgccaactgc taaacgactt gcggaagaga ttttaaataa gagggcgtga
    22981 taaagctcct taatttcgag tattaagaga ttagttatct tcataacaaa aaacgaagag
    23041 aggactaatt gcccttctct tcgtttttta ttaatccatc aatttcgtat attttacttc
    23101 atcgatcgtt tttgttcctg caagttgcat cgtgatcgac aattctttgt tcaggtgttc
    23161 aaaaacagat gttactcctt ctgccccacc tagattcaac ccataaatca ctggtcggcc
    23221 aatcgcaact aagtcagcac cacttgccag agctttgaag acatgctctc ctcgacggac
    23281 accagagtcg aaaatcactg gtacacgttt gttgactact tcggcaattt ttggcaatac
    23341 ttcaaaggac gcaggacctc catctagttg acgtccacca tgattggata cccagatacc
    23401 atctgcccct gcagagatag cgattactgc atcttctggc gattgtattc cttttacgat
    23461 aactggaaga tgggtgattt ctttgattgt tttgatgtca tctggtgtca agccttgttt
    23521 tgcagctgca taaatttctg cgattccttt tccttcgcca ttaccacttg cactttgttc
    23581 gctatacgca gctaagttag gcattggtaa tggaaattgg aattgattga tgacgtcttc
    23641 ttcacggtaa ccaccgagcg ttgaatctgc cgttaaaatg atagctttag cccctgcttc
    23701 tactgctttg ttcaaaatga actcattgaa tctgtcgtct ttactcatat ataattggaa
    23761 aaactgcggt gcgcctggcg ctgcatcggc tgcgtctttg attgtcgtat ttgcataagt
    23821 gctgatggaa aagattgatc cagcagcagc tactccttta gctgtatcag cttccccttt
    23881 ttcatgtgcc aatccttggg ccgctgatgg cgcttggata atcggtgtat ctaattcaat
    23941 tccgaaaaca gatgtatgca aatcggctga gtcgattccg cgtaatatcc gtggcatgat
    24001 tttctttgta ttaaaagaag tcgtattttc tttcatcgtc cactcatctt cagaaccacc
    24061 gcgaatatag ccaaaagctc ctgcttccat gcgctctttt acacgacctt ctagttaggc
    24121 aatgtttaca atatcgattg gatgttcttc attacttgta tgataagtca tagtagatcc
    24181 ttctttcatc ttcttgatta catataaatc atactaaact tacaaaaagt aagcaaacat
    24241 ttactctcag atacttttat cgctattctt tccaaataaa tcgacttaca agctgatcta
    24301 cttcttggtt ttcatgaagc atactatgag aggcattttc acctgtcact actttttcct
    24361 ctatttcatt tccgcgttgc ttcaacaacg catagaccgc taatgcactg tttaacggta
    24421 ctgttccatc actcaagtct gtttcatcta gttgaccagc aatcaagaaa aatcgagtgg
    24481 ttataggaat attaccgatc atttgctggt aatcttgata gcggttagaa acgacagcag
    24541 gcccctttgc taactcatct gtcagagact gcgcactatc atcgacaaaa tcattaaaag
    24601 gcgcgccaat tgctgttaat gtctgaactt gtggcaatga cgtatcctgt ccatacgttc
    24661 ctaaatagcg tagtgcacta actcctccca tggaatgccc cactatgttg actttatcta
    24721 tgccgtagtt ttctttcaga tacaaaagac aagttttgat ccattctgct tgattccact
    24781 cgttattttt attatcttca aacaatactt ggaccatcgg attgtctgct tttccagaca
    24841 aatctcctgt tgcttgtatt tgtccatctg ttcctactgt taaaaccaat tcttttactg
    24901 cttgctgatt tttttccaaa cgccgcaaca tccctttaaa ggaattttct gtcccgctgt
    24961 agccgtggaa aaaaagtgtt ggaatagtgg ttttttctat cactttactg gattctgccg
    25021 ttttttcttt atcagaaact tcagtagtat ttatcttcgt cgtctggcaa ccacttaacg
    25081 caaacaaact gataaggact aaagctgctg cagttgcacg tttgcataaa tttttgattg
    25141 gttctgtcat acacctcttc ctttccatat agaaaaaaga aagacttgaa aggccaatca
    25201 tatgatcgac atttcaagtc tctttattaa tcgattttat ctacttgatc gaaatcaagt
    25261 tctgtactgg tttcacgtcc aaacatatcg atgttgactt tcaatttttc tttttctccg
    25321 tcaacttctg ttacttgtcc ttctaatcca gcaaatgcgc cttcgatgat tttcacgact
    25381 tcgccaactt ctacttctag atcattttgt cgcaggctca taccgataga acgcaagata
    25441 tgattgactt cttctggaag taatggtgct ggtttgcttc cggctccgtg tgaaccaacg
    25501 aatcctgtca caccaggtgt gttgcggaca acataccatg aagcgtctgt catgatcatt
    25561 tcaacaagta cgtatcctgg gaatgtttta tgaacgattt ctttttcttt cccatttttg
    25621 acttcagttt ctttttcttc aggaacaacg acacggaaaa taaagtcggc cattttcata
    25681 ctttgcgcac gagattcgat atttgctttt actttgtttt catatcctga atatgtatgc
    25741 aagacatacc agtttttttc aaaagattcc attgaaggct cctcatttca ttgtaaaata
    25801 aaaaaacctc agtacacccg aagtttttct ttcgcttcat tatagcacta aaagtacgtt
    25861 gtggctagcg agttatttta aaatccagcc aaataagctt tggatggctg tatccattac
    25921 gtaaaacatc aatccgaaaa taatagaagt ttcgatgact actaacgtat ctttacggag
    25981 ttgttttctg cttggccaag ttacttgttt gatttcatct tttacgcttt ttagaaattt
    26041 catgagacaa cctcccttgc tactgtttat ttcgtttctt tatgtaatgt atattgatta
    26101 caatatttac aaaacttatt gatttccaaa cgttcgccgc tttttccttc actgactgat
    26161 tttgtgtagt tgcgagaccc acaaacggaa caagcgagtg ctgctttttt ctttgccatt
    26221 tacttctgcc cccttgctga gaatcagact tatacttcat aacagtatca cgtaactttt
    26281 tacttgtcaa tttgtgaaat aaactatcta ttgttttgga taaaattatg atatgattaa
    26341 tttgaaatta agctaaaatg agacaattgg aggtatagcg atgctattaa aaacacttgt
    26401 atataagaaa aaagatctga caaccgttac agagactagt acattagaag aagcattaaa
    26461 aattttagaa acttccggat accgttgtgt gccgatctta gattcttcag gtaatatttt
    26521 ccgtggaaac atttacaaaa tgcatatcta tcgtcataaa gcaaatggcg gtgatatgac
    26581 gcttcctgtc actcatcttt tgaaaaacgc tacaaagttc atttacctgg atacttcttt
    26641 cttcaaagta ttctttacga tcaaagagct tccttatatt gctgtccttg acagtgaaaa
    26701 tcatttttat ggtattttga cacatagtac gttgcttaat atgctctctc aatcttggag
    26761 cgtagaacaa ggaagctatg tactgacaat tgcttccaca ggaaagcaag gagatttggc
    26821 tgctattgca aaaatcattt caaaacacag cagcattgcc agctgtatta ctcttgatat
    26881 cgaaaaagac gaatacattc gacgtacatt gatcacgcta ccggctaaca ctgaagcgaa
    26941 agtatgtgaa acgatcgtca accacttaga gaaaaagaat tataaagtgg tagaaattga
    27001 aaatttgcaa aaccaagaag cataatcaaa aagcgaaaaa agaaaacagc taatctgctt
    27061 tcttttttcg ctttttataa ttagacacgc ttttcaaaat caagcgcgcg atctaaataa
    27121 tacatcaatg gtgctgaaac agccatgacg ataaactcac ttaatgcaag cgtgccatag
    27181 gttgtccaaa atgcttggcc acctgttgga actaacatat aagcaatcag tcccatgctg
    27241 atggtaaaga agatcgtgtt caatactaaa cgcatcttta catttttcac tttgttttgc
    27301 aataaagctg tcaggcctaa agaaagcaat gtttggccgc caccaaaaac cacatccatg
    27361 ataccaaaac caaagaaggc attatagacg atgaccccgc ctaaaactcc ccaaagcaat
    27421 ttacggttaa agacaactaa atgattcaaa ctttctgaaa tacgaaactg gatcggccct
    27481 gaggatacag gcgcaactaa aatagttaac gctagataaa gagccatgat gatgccattt
    27541 acaacgatta cggataaccg ttgtctgctt ttcgtttttt gcattttctc tcctcttttc
    27601 tcctagtttt tttaacgcgg gatggttgat gaaccgcggt tatgtgaaac aaacaataat
    27661 tataacagac ttttcattta tttcaatccg tcttatctgc ttttaaaaaa gcaaaagctt
    27721 aaacaatgta aacgtttgct aaaaatcgtg ggatatggta taaagtaagt gtaaggggtc
    27781 ataagaattc ccagtaaagc agacgaagta ggatctgcaa gaacagaatt gttgtgaaac
    27841 ttaaataaat aaaaaaggat gtgggaattt gagcaacctc ttactagaga acggtctagc
    27901 aagcagctga agatctaagt ggacatgccg aaccttggaa cttctcctta cgtaagtaat
    27961 ggatcatgcg cttgctaggc ttttttgtgt ttttcggtct tcggaccttt ttcattttcc
    28021 tagacttctg ctataataac caagaattaa ttttgtaaca gatttttttg aaaaaacaag
    28081 tttctttcat tcaaaaaata gaaaaagctt gctaattatt ggttaaccag caaacaggag
    28141 tattaaaata tcttgtttta ttgaatagca ggaggaaatc atgaaattcc attatcatat
    28201 attgatcaat ccatcggcag gcagcggaaa tggctataaa gtagcagaaa gaattttacc
    28261 ggtattaaaa aataagcata ttgactatac acttcattat agtgaataca aaggacacga
    28321 tgctgagatt gctgaaactt tggcaaaaga aacattgatt ccttggatag aagaagaaca
    28381 gaaaacaatc gatactttcc cccttttgat catcgtagga ggtgacggca ccttacatca
    28441 ggtacttgat actttctatc agatggaagt agaattccca gttgcttata ttccagcagg
    28501 ttctggagat gattttgctc gaggggcagg ccttccaaaa aatcccaaaa aaggacttca
    28561 gctgatttta gcagctcaat caccagaaaa agtccacata atggcttatg aagaaaaaat
    28621 aagtgaaaaa aaaggaatag ctgttaataa tttcggtata ggattagatg cagctatcgt
    28681 ccatgcgaca aatcattctt ccacaaaaaa gcgattgaac aaatacaact taggatcatt
    28741 ttcgtattta ttctctattc tccgtgcttt attcactcaa aaaggatttc caattctggt
    28801 agatgcagga ggaaaacaat taagtttttc aaacgcattt ttatgtacag caacgaagca
    28861 tccttttttt ggcggaggaa tcgcgattgt tccaactgct gatgcgtcta aaccagtcat
    28921 tgattttgtc gtggtcgaac gaatcaattt ctttaaaatc ttgtggctca ttcttttact
    28981 tatacagaaa aaacaattga aatcgaaata tttccatcac tacacaacaa acagattacg
    29041 tatcgtttca acaacaccgc aacatggtca agaagatgga gaagaaatgg aaaaacgacc
    29101 ttttgatatc acaataacca caactaaaca gttgttttgg tgttaataaa agaggttttg
    29161 tcagaagcta catctggaac accgtttatt cggaaaaaag gactgtgaca cgacttttgt
    29221 cacagtcctt tttttactat gcagttaatt ctttgcccaa ttgggttgcc atcgatagtt
    29281 tctttcttta cccaaaataa attggatcat tgaaaacacc gcagcaaaag caactaagac
    29341 acaaccattg aaccaaaaag attctgcaaa tgtttgattg taactgagtg tttcactgat
    29401 caagttatta ttttgaacaa accaatatgt tggtgtgaat gccgctattt tgctaaccat
    29461 ttctggcaag tattctgctg gtacaaacac cccaccgata aagcaactgc ctgtgataaa
    29521 aatatctttg atcccaccgc tggtttctga gttttttacc aatgaagtga tacaagccga
    29581 aaagctaatg atcggcaata aaaacaagaa agtatttaaa atatgatacc ataccgttat
    29641 atcccacgag gtgtggatca ctaacagaac cattagaagt aagaagccac tgaacaacag
    29701 cagcgagtaa ctaatcaaac taaaggttac tttgcgattc aagtttcgtt tggtaatggg
    29761 cgcactctgg tttcgtttac tgatctcttt gcgattaaat gctagattga tgacgctgaa
    29821 accgctaaaa atggatagaa acaacccata agacaagaaa ttaaaggttg tgcccgtcaa
    29881 cagctttttc atccgctgac tatatcccgc acttagctca acttctccag taaccgagag
    29941 tgccatttgt gtctgttcca tagctgcatc gattgtttta tcttcttctt gaaacagaat
    30001 cagtgtttgc aaaaaggtgt tcacttgctg tgtaacaact gttttagaaa aggcatctgg
    30061 gcgactctgt atcttgatcg tcggcatctt tcctacttcg acttgttcgg taaagtctgc
    30121 aggcagatgt aagataatgt ttacacgatt aaaataaaga gcatcatcga tttctttttg
    30181 tgaggttcca tccaatgtaa cgactgtttc cttgtcattc aaatatttac gaaggccatc
    30241 gactacaggc gactcttctt cactaatcaa ggcgattttc gcatcttgca gagaggtatt
    30301 ttcaacatca atattttgcg caaaaaagaa tgtggcaaca acagtgataa ttacacctat
    30361 cagtaaattc gatttatttg ctttaagcaa tgtccaaatc gttttataaa gcgtcataac
    30421 gcacccctct ttccatccaa gcatttccta acgcaaaaag gaaaataaat ccgatcaacc
    30481 atagaagatt ggtataaaaa ctagccaaat cagtgtagaa ataaagttta tacaaacttt
    30541 cgctgatcaa gttgacgaga tttaattgac caacaatcgg aatatgaaga tcaatccaat
    30601 acttcacttg ttccgacccc atcataccag caaaaaagct catcgcaatc gtcactgaaa
    30661 tcaagatgct atccttttgc accagattca tttttggtat caaattacca accaatgtac
    30721 ctaacaaaat cgcacacaac gaccccagag cggtaacaat catcaaccat tgccaacgtt
    30781 caccaaagtc tacttgatag ataaaacgaa agacagctaa cataatataa atctctgtca
    30841 aaacaatcgt aaagcttgct gccaaattag cgattgaaac taacgattgc tttctaggaa
    30901 tcaaggacaa gcgaatacca tttgacgatt gatttgcttg ctgatcctgt acattgcgga
    30961 ccccccacat cgtcccgtag agaatcgcca ttccaatcag agtgaagaaa taaaaacttt
    31021 tgaaactcat attacgacct gcatgaactt cttgaaaaga tacttcttgt tcaaaaacag
    31081 tcatgatggg cgcgagatca acgttctcca cttctgccac tttactcgaa attataccaa
    31141 tacgctgtaa aaattgatcc atgacgtttt tcatcaacgt ctgactcatt cctgcttgac
    31201 ccacatggag cgaaacagat gaaccatcaa tgagataaaa accagccaaa tcatctgcat
    31261 ttagcttttc attcgcttct acttccgata gttcctgtac ttcaaataat ggtttatcat
    31321 tgacttcgac ttgttctaag actgtggtaa aattttccga aagcgctgtt tgatccgctt
    31381 tgattacaat tccagtatta atcgtttcga gattgccacc ttgatcaatc tcgccaaagg
    31441 ccgccataaa catcaatcct aaaagaattg gaaaggccaa tgtccaaaac aacatggatt
    31501 tatttcgcag cagtattttt gtgcgatatt tataaaaatg ccaaaacatt atttcccctc
    31561 ctctagtctc tcaaatcctt gccagtaatc tctaaaaaga catcattcaa ggacgcttct
    31621 ttggttgcta tttttccgta actgatcttt tcttcttgta agattgtaag aatcggcaac
    31681 aatactgtat ttagttcagt agttgttact tggagctgac cttttttata agcgattcca
    31741 tcagaagcta ttgttcgctg acaacacgtt ttctgggagt aatgggatgt cgatcgtcaa
    31801 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    31861 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    31921 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    31981 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    32041 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    32101 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    32161 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    32221 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    32281 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    32341 aagcatacag ttgatggcag tcgatttccc actgccgttt ggtcctaaca gacctaagac
    32401 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    32461 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    32521 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    32581 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    32641 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    32701 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    32761 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    32821 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    32881 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    32941 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    33001 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    33061 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    33121 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    33181 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    33241 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    33301 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    33361 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    33421 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    33481 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    33541 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    33601 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    33661 taccaaggga gggacaccaa tgataacagt agtcattatt gagatgatcc atttgtgacg
    33721 aaatcgttac aaaccatttt agaaagcacg aaagagatcc gtgtgttagg cattggtcat
    33781 tgtgccaagg atgcgctagt cttatacgaa acccatcgtc ccgatgtttt gctgacggac
    33841 atccgcatgc ctaaacaaac gggcatcgat gctgccaaag aaattttggc taaatttccc
    33901 aaagccatcc ttttgctttt gacgacattc aaagatgaag aatacatccg cgaagcattt
    33961 tccatcggtg tcaaagggta tttaatcaaa cagaacttgc aagcgattat tccttctgtc
    34021 aaatccgctt ataatggaca ggccgtattt ggtaatgaaa tcatcgagac tttcactcaa
    34081 atgatgaaga ataaaccgac gattgatagt catgcttatg cttcttttag tgaacgtgag
    34141 cttgcaatca tcaaagaagt agctgccggg aaaaacaata aagaaattgc agatgccttg
    34201 tacttgagtg acggcactgt tcgcaattac atcagccaat tactagaaaa gctagattta
    34261 cgggatcgca cgcaattggc tatctatttt tatcagcatt tgcaataagt cttatctaac
    34321 acaaaaaaac ctgaatgatg ctccttcgca tcattcaggt ttttttcaca tcttctattc
    34381 aattgtcccg caaaccattt cctcacgatt gaaagaatca aggattcgca gggctgccag
    34441 gattcgttgg attgttcggc gtgttaggcg gaaaaatagg cgccttgtct aacgtttttt
    34501 ctagttttga ttcttcacga tcgtctcgtt ctacatcagg actttcattc aatttgaatt
    34561 ctttttccat ctcatctaac tttttaaagt cattgccaga ttcttttgct aatttcgcta
    34621 atttatcttc ggtttcttta gccataaagt aacgcccccc ttttgatttc agcttagcat
    34681 atcacactga aaaaacaaaa gaaaacgcta accaacgatc atttttagct atttctcatc
    34741 tttaaaatca agcatttttt gccggtataa aatcgtaggg agaactgttt tccataccaa
    34801 tcatcggatc tactaactgg ttatcgatca cttctgctgt aagaacgaaa tctttagaaa
    34861 cagcaggttc tacctcttct ttcttttctt ctccaacaaa tgaagaaaac agatctggtt
    34921 ccactgtttc cattacttgg tttttcgttt cattcgtccc actgtcatct tctacaggta
    34981 gcttttcttt tacaacccgt ggctcttttg tatagttccc atcttcaaat ggatcatttc
    35041 cgaccaaaga atcttcataa gctgctagtt tggtccggag agtgatattc attttatcat
    35101 tatccatgat ccttgatttc aacgtagtca tccggcttgc tgattcattc gctacacaag
    35161 tgacataggc ttgctcttcc cctaacaaaa tcaacagttc cttactgcga gtcactgccg
    35221 tgtagagcaa attacgctga agcatccgct gatattgatg gaccatgggc aaaataacca
    35281 tcttgaattc actgccttgt gatttatgga ttgagcaaca ataagaaaga gtgattttat
    35341 tccattcgtt tcttttataa gtgacctcat ttgcatcaaa ctggataact aattcatcca
    35401 ctttatcttc agaatctttt gccaagatga tacccgtgat ttctcccata tctccattga
    35461 atacattcaa ttcgggagta ttgactaatt ggaggacttt gtctcctatc cgataaacgg
    35521 tgtcgttcca atgtacttcc ttttttccag gtttccctgg attgaatatc tcctgcatca
    35581 ttttatttaa cgcatcgatc cctgcaggtc cccgatacat tggtgctaat acttggatat
    35641 cttgtgcacg gaatccctta tttttcgctt tttccacaat tttagagatc aagggttcaa
    35701 tttgataagc atcacttcgg aaataggaac gatctttttg attctttgtg aaatcttttg
    35761 gcagacgtcc ttctttgatc tcatgggcaa gaggaataat actagaacca tcaccttgcc
    35821 gataaatctg attgagttcc attttgggaa tttgttcgat ttccaaaaga tcatggagta
    35881 cttgaccagg accgacagag ggaagctgat ctttgtctcc tactaagata acttgcatat
    35941 tcgtcggaat cgctttgaat aatgtgttag ccagccatgt atcgaccata gacatctcat
    36001 caacaatcaa aagtccgcct tctaattctt tcgtactgac tgaaggtgtt ttttcccgtc
    36061 cattcagccc cagaagacga tggatcgtac tggcaggcag acctgtcgtt tcgttcattc
    36121 gtttagctgc tcggccagtt ggtgctgcaa gtagaatagg aaaaatttct tgggtatatt
    36181 ttgaaggatc caattccagt ccgttcaact ctgcaaaaag attgacgatt ccgttgatca
    36241 cagtagtttt ccccgtacct ggtcctcctg ttaaaataaa tagaggggaa cggattgctt
    36301 cagcgatagc ttgttcttgc gaaggtccat actgtatgcc gaatattttt tcgatacgcc
    36361 gaatattctt ctgcacttct ttttcaggat aatggatttc ttttttacga ctgagaaggc
    36421 gctggatcga attaccgatc ccccattcag aaaagtacaa actgttttcg taaagattag
    36481 tctcttcttg ttgtatcttt ccttcttcaa caagttggat aattacagta gcaacctgat
    36541 caggctggat ttcaattggg cgacttgttt ctaaaatacg gatcgtttgc tgaagcaatg
    36601 tctccgccgg tacgtatgta tctcctgttt gaactgcatg ctgaaaaatc tgatgcaaga
    36661 tagctgctcg aattcttctc ggtgaatctg ctgcaatacc gatttgttcg gctagattat
    36721 ctgcacgttt gaacccgatt ccttctatgt cttcgactag ctggtacgga ttttcttcga
    36781 tgatatccaa agactcgttc ttataggcct ggtagatact gaaagctaac tgactaccga
    36841 acccgtaacg attcagtccc atgatcactt gatccatccc gtggtttagc cgaatcgtct
    36901 cagcaagcat ttctcttttt ggcttcgtca aaccggagat ttgttttaat accgaaggat
    36961 cagcaatgat tttttcgata gcatcttctc ccagcaattc tacaattttt tctgctgttt
    37021 tcttcccgat tcctgggaat ttttcgctgg aaagatacgc tacgatccca tttgcagttg
    37081 ttggcttttc ttgctcatat ctttcgagtt taagctgcct tccgtattta ggatgatcca
    37141 ctaattctcc ataaaaacga taagtctcat tttcttgaat atcgccgaaa cttccggtga
    37201 ctacaatctc tttttcacgg taatcagctg tggtttcact gatgtgtacc aaaagcactt
    37261 tgtaaaaatt actaggattt tgaaaaaaaa tcgcggcaac tgtaccaacg aaataaggca
    37321 tttcttctgg ctgcatcgga agccgcctcc ttcttctata gtaaaggttc tggtgctgtt
    37381 tcagttccta aaaaatctgt ttggttccat actttcagtt catatggcaa taatctgcaa
    37441 ggctcttcag tctctaaaat cgtcaaacta ctattgaaca atccacccat ttcacgcaac
    37501 tcacttagct cttttcctgt catccattga atggctgcag ttaaagaagc tccatgtcct
    37561 acgaataaaa gtgggccatc tttatgttgg gcaaccgcat ctgctacaac agtttcgata
    37621 cgtgtgattg ccgattcaat cgtttctccg tgaaaaggag aaggatcata cagatctaaa
    37681 tgattacgca aattcggcag attatccgga tatttctggt acatttcatc gatcgactga
    37741 ccttctaaag tacccagccc tagttctctt agcttatctg tataaaaaat ctctaccgga
    37801 cgagcaagct ctttgttgat accttctgct gtatcacgtg ctcgctttgc tgtactggaa
    37861 taaattgctt taaaaggaac atattttacc tttttcccaa atgctttgat ttcttcgtaa
    37921 ctttgtggca aaagcggaga atcgccattg ctcccttgaa aacgtctttc ctgattccat
    37981 tgtgtcttcc catgtcgggt aaaatatagt tccatacgca gcaaactcct gtctttcttt
    38041 tattttactc tataataaac tgtctaatcc agcttgtcat tttcatagtg atgcgtcaat
    38101 tctaaattag ggaatccttg ctggcgaagt gcttcataca ctatcattgc agctgtattc
    38161 gataaattca atgagcggac atgctcatca ttcataggga tgcgtaaaca cttttcttcg
    38221 ttttcacgca taaatgtttc tggcaaaccg gttgtttctt ttccaaataa aaagaagtgc
    38281 tcttctccat cagcaaaatt ttcgtcacta tatactttat gggcaaattt tgagatcaaa
    38341 tgtagtttac gattacctaa aaatgttaaa aaagcttcta aattactgtg gtaagtaata
    38401 tttacatcat tccaataatc caaccctgcc cgttttagat gtttgtcatc agttgaaaaa
    38461 cctagtggct cgattaaatg aagcggagta ttcgtggctg cacacgtacg ggcaatattt
    38521 ccagtgtttg cagggattaa tggttcaaat aaaacgatat gattcatcag gatcattcct
    38581 ctcatattta tgttcgtttc tattttctga caatttgatt tttgcataaa aaaaaacgta
    38641 tcaactcggt gtcagtcact gcgagtcgtt acgttagtga agctcttctc actaactttt
    38701 atcagaacag gaacctgata aaaaccaatg aaaaaacaac ttgttgctaa tataacaccc
    38761 tcaacttttt tttgcaacct ctactcatta aaaactgcta gaaaaacgtt ttctcttagt
    38821 tccttttaat aattctatgt caattgtaat cttcttcaaa ggattcttat ataagtctgc
    38881 tttgattcgc tcttctacct gccattctaa aggtgacatg gccaaaagat ctttttgatt
    38941 ttcctctggt atctcaaatt cataggttac acgctgacgt tcagttaatt tcattgcttc
    39001 agcaaacttg gctactacac gttcattgga ataactctgt ttttcaggtt gattcggata
    39061 aaaagcctga cgtagttcct ttaaataatt ttcttgtggc accaccttca acacttctcc
    39121 atcttctgag agtacacgtt ggaattcttg gtaatgagaa ggcgaaaaga tatttaaaac
    39181 cgcgttgaat gtttgatcag caaacggcaa attggtcaaa tcagctacac accaaaatgc
    39241 ttcggcagat tgttctgtag ctgcgtagac tccttctttt gaaatatcaa atccaacagc
    39301 attttgaatc tttttcaatt ttgaaagttc attcaagaag ctaccttctc cgcagccaac
    39361 atctaatagc gagacttctt caggtaaatg ctgcgcaata gtctcaataa cgggctgata
    39421 catgccagat tggatcattc tacgccttgg aacgaacatt ccttgatcgt attctgtttt
    39481 aaccgcatgg gataaaaaat aaagtgttcc ttttttggaa aggtcaaaac ggtgattatt
    39541 tttgcatatc aagccattat cagacttttt tacttcttct tggcaaaccg gacagcggaa
    39601 cagctgatga ttttctgcca aaaactggcg tcctcggtca atttttttta acatagttcc
    39661 ccctcatttc tgttttatct taccgttaga tgctcacttt ggcaactgct aaaaatatga
    39721 tacaatgcct agaagaaagt gaaagataaa ggagaagatt agatgatcaa agaattttgc
    39781 gctgaaaact acacatctat tcctctagca attgctagag gagccgatcg gatcgaattg
    39841 tgtgacaact tagcggtcgg tggcacaacc ccgagtactg gtgtgatcga agaaacgtta
    39901 agttatgctg gggaaaaaga tatccccgta atgacgatta ttcgtcctag agggggcgac
    39961 ttcgtctata acgatatcga attgaaaatc atgcatactg atttgattga agcaaagaaa
    40021 ttagggacgg atggcgtagt atttggttgt cttactcctt caggctggct agacgaagag
    40081 gccttagaac tattgatcga aacagcagaa gggttgcaga tcaccttcca tatggctttt
    40141 gacagtattc ctgaagatcg gcaattcgaa gcaatcgatt ggctggtaga acatggtgtt
    40201 gaccgtatct tgactcatgg cggtcctgct gacaaaacta ttgtagaaaa tttcccacgg
    40261 cttaaagaat tgattgccta tacagatggc cgcttaatca ttttgcctgg tggtggtgtc
    40321 actgcagaga atgcagcaca tgtagctaaa gaattgaacg taagcgaagt acacggaacc
    40381 aaaatcgtgg atcttcagtt ataatcttat aaacaaaaaa acatttgcaa caggcataat
    40441 gcttattgca aatgtttttg tttttttaca taaaatagcc cataaataaa gaagcaatat
    40501 tgaaataaat cagtacactc gtcaaatcgc tcaaagtcgt gataaaggga ccgcttgcta
    40561 ctgctggatc aaatcctaga cgatccatta gcatcgggat taaactacct gcaagattcg
    40621 ccactgtgat tgcaaatagc atagccatcc ctatgacaaa ccccaagata aaattatgtt
    40681 tccaaaaacc tacgattaga aaaatcgtga tccccgtaac agctcctgtg acaacgccgg
    40741 tcaagacttc agccaaaaca agtcgaacaa atccatgatc tttctcatca gaaatcgcaa
    40801 gtcgacgaac agccacagct agcgactggg ttccagcatt accggcagtt cctgtaatca
    40861 gcgaaatgaa gactgctaaa atactcgctt cacttaccaa gtcttcatag tgactgatta
    40921 aagaagcggt cgacatacct aaaaacaaca gagtgatcag ccaaggcaaa cgtcgagacg
    40981 ctgcctttac tggattttca ttaatttctt ccacattgac cccggcaagt cctgaataat
    41041 cgctagcagc ttcatcatca ataacgtcga tgatatcatc gactgtgacg attcctaaca
    41101 aatgatcatc ataatcggta acaggaagag ctaagaagtc ataatctcta aatgtttgtg
    41161 ccacatcttc ttggtcgtcg cctacatgaa ctgaaagcac tcgttcgctc atcagatcag
    41221 aaatcattgc gtcgtcatca ttcacgatta ggtcgcgcag agaaataacc cctactagct
    41281 gaccttcttg attaacgaca tagatgtaat agattgtttc agctacatct gcttcgttct
    41341 tcagcacgta catcgcagag cgaacagttt gattggctac gatcgaaaca aattcagttg
    41401 tcatgatcgc gccagccgtt tcatcctcgt aatggagaag ttccttgatt tcactggcat
    41461 cgtctgccga catcaaactt aaatatttag caatttgctt tttatccagc gtattaagca
    41521 agtcaacagc attatctgta tacatctcag aaagcatatc agctgcatag ctaggacgca
    41581 tttcatctag gtattctttc atatgttcgt tgtcttcttc aatcacatcg aacatatccg
    41641 ctaattcttt aggcgacaga taggaataga tcagctgcct gttctcttct gtaagagatt
    41701 ggtagaattg cccctgctca tagatatgca tctctaaaaa actgtttctg aatgcctgaa
    41761 tattattttc ccttaaatct tgagtcaact gggcaaatct ttcctctaat tcttgatttt
    41821 catccaaacc aatctcacct cgccttattc ttcaaaccgt ctcacaactg cctccatgtc
    41881 tgcggctaaa ggctgcttga actccagcaa ctcttctgta aatggatggt aaaaacgcag
    41941 atcataacaa tgaagggctt gtctttttat tcccagatcc attcgcccgc catacatatc
    42001 atcaccgagc agggcacagc caattgcgga aaaatgaact cttatttgat gtgtccttcc
    42061 tgtatgcagc tggatatcaa ctaacgcgat ttctgttagt cgcttctcta tccagtactc
    42121 agtctgtgcc gaacgtcctt catcagagac cattcgcttc aatagcgaag aataatctcg
    42181 ggcgatcggc aaatcgatat gtccatgtgc cgataaatct gaaagccttc cactgactaa
    42241 ggcctgatat tttttcacaa acttcttttc acgaagttgc atatctaatt ttgcgtgcgc
    42301 aaatccatgc tttgcaaaaa gcatcaaacc agatgtatcc cgatctagtc gcgtcaccac
    42361 atggattact tggttttcgt aaccttgttt tttataataa gcctttacac gattagccat
    42421 tgtcccattt ggatggtatt gggcaggaat agacgaaacg cctgctggtt tatttactac
    42481 cagaacgtgt tcatcttcat acacgatatc gatcggtgtt tcatccaaaa gtacggtttc
    42541 atgttctcct tcagcaggaa tcacaatggt taccttatca tccttagcta gagaaaacaa
    42601 gacattttct acttgatcat taactttgat ttgaccgcct tgaaatttta ttttcgctaa
    42661 cagacccttt gagatccctt tttcttttaa aaaatatttt acttgctgag aatgatcttt
    42721 ctcataatcc catgtaaact gcatatcaat cctcactaat aaaggcatct ttcacacgat
    42781 gccaaaaatg catatgtcga taagaagcaa aatggatccg ttcttctgct attcgataat
    42841 aaattgagcg gatatttgct tttgcgacat tcaattgatc aaccgttaca agataatctt
    42901 ctgtattttc caattttatt tctagccatt catcatgggc aatcacgatc ggagaaccca
    42961 aagtacgaaa cactcgatta ttcagtgaag caatctctgc caactgaaag gcattgatac
    43021 taggatggat cacagcaccg ccgacacttt tattatatgc tgtcgaacca gtaggcgtag
    43081 aaatcgtcaa tccatctcct ctaaaacttt caaacagctc gtttttgatg tatacatcgg
    43141 ctaccatcgt acgattggcc cgtttaatcg ttgattcatt cagtgctaaa aaatgctggt
    43201 ccggtgtttc atccaaataa ctgatccgaa catccagcaa gggataacta acactttgtt
    43261 cccggttcgt tcgtaagctg tctactagtt cttccagctc gtaatcccgc caatccgtgt
    43321 aaaaccctaa atgacctgta tgcacgccca agaaacgcac atcattcaga caatgactgt
    43381 agtgatggaa cgccgacaat aatgtgccgt ctccgccgac tgagatgacc aattctggct
    43441 catgatcatc tcgttgaatc cctgcttgtt ctaaaagtgc gttcaaacgt tctgtcactt
    43501 ctatagtctt tgcttcttta ttatgaacga tcgctacttt catcccctgc ctcctctctt
    43561 tcgctttctt tcttcaaaag cgttcgatag tagacatcat ctgattttcc tcttccatgg
    43621 gagaataacc gctgtgcttc ttggatttct tcacggatac tggacatctc ttcatccaac
    43681 tgataggcag cttctgccgc acgctgaagt cgttcactca tttcttctgg aaaaacgcct
    43741 tgatatttat aattcagcga atgctcaatc gttgcccaga aattcatcgc aagagtccga
    43801 atctggattt ccgccaaaat tttcttctca ccgctgatca gctgtacagg atactcgatc
    43861 accagatgat aagaacggta gccacttgct tttttatttg tgatgtaatc tcgttcttgg
    43921 agaactttca tgtcttttct tttacggatg atctcaacaa cttgatggat atcttctaca
    43981 aactgacaca tgatccttaa cccggcaata tcagacattt cttcttctaa acgtcccatt
    44041 ggaatatgcc gtaattgtga ttttgttaca atactatcga ctggcttgac tctcccagtg
    44101 acaaattcaa tcgggacatg tcgattttgt tcacggaact gtttgcggat cccccgcagt
    44161 ttcactttca attctgatac agtttgttca tatggtgcta aaaatgcttc ccaatctcgt
    44221 tccatagctg atacctctac ttcattaaca ttcattgttt attctaccat atatgcaaag
    44281 ttttttcgta ctcttgattt atgcattgac caaaaaaaga aaattaggca aaatagacaa
    44341 aaaggagtcg atcaaatgac acaaatgctt gaaatcgaat ataaatctat gctgacaaag
    44401 caagagtacg agatattcat cgctcactat caattaacag ataaagattt ccgtgtacag
    44461 actaatattt atttcgatac cgttgatgaa cagctgaaga aacaaaattg tggcctacgg
    44521 atccgtttcg ttggtcatca agctgaatat acattaaaaa cacctgctga aaaagggcgt
    44581 ctcgaaacaa cggatacctt tataacagaa gaagcagaag catttatctt cgaaaaacgt
    44641 ctgcctcgtt caggcgcagt ttttcaaaaa ctttctgatt tgaatatcga tcctgcttca
    44701 ttaatccaaa ccggaaagct tacaacaaaa cgggctgaat tccctattga agaaggactt
    44761 ttagctattg atgaaagctg gggagacaat ctacacgatt ttgaactgga actagaggta
    44821 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    44881 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    44941 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    45001 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    45061 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    45121 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    45181 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    45241 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    45301 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    45361 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    45421 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    45481 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    45541 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    45601 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    45661 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    45721 taattaaaaa aatacgtcga ctcccttaca agagagccga cgtatttttt tcgtttctat
    45781 tcgagaaaat caaaaataga aagccttata aacgatcgat caattcttct aattcattta
    45841 gacgttgttc aaacatcgac attgcatctt caatatatgc agcctgtgtc atatcaactc
    45901 ctgctttttt cattacttcc acaggataat cgctgttacc tgcttttagg taagccaagt
    45961 agttctctag tgcctctggt tcctggttta gtattttctt cgccagtgct gaagcagcag
    46021 aaaagccagt cgagtattgg aaaacatagt aattataata aaaatgcggt atccgtgacc
    46081 attcgaattt aatttctggg tcttcttcga ctgctggacc ataatatttt gcattcaatt
    46141 taccataact atcacttagg tattcactag tcaatggcac acctttttca tcttccgtat
    46201 gcatgaaatg ctcgaattca gcgaattgtg tctggcggaa aactgttcct ttaaacccat
    46261 ccaagtaatg gttgagtaca taagcccgta cacgagggtc tttttctgtt tccaataaat
    46321 actccgttag gatattttca ttcgttgtcg aagcaatttc tgctaaaaag atggagtagt
    46381 cgccgtacac ataaggctgg ttcgaacgag tgaaataact atgaacacta tgtcccattt
    46441 cgtggacaag cgtaaatagc tgatccagcg tatcatgcca attcaataaa atatatggat
    46501 ttgtgtcata gcttcccgaa gaataagcac cgcttcgttt ccctttattt tcgacaacat
    46561 cgatccaacg ttcagagaat gctttttcta cgatggccat gtattcttca cccattggtt
    46621 tcagtgcttc taaagctttt tcttttgctt cttcgtacgt aaaggtaatt ggagcttccc
    46681 ctaagaccgg tgtataaaga tcatacatgt gcagtttttc cacttctaat aaacgtttcc
    46741 gtaattccat gtatcgatgt aacaaaggca aatgcttgtt taccacgtct accaaagtat
    46801 cgtatacact ttcaggaata tgattattgc tcaaagacgc ttctctggca gagctgtaat
    46861 tacggacttt cgctttaaaa ttatgtcctt ttatatgtgt gcctaaagta gaagcaaatg
    46921 tatttctaaa ttgttcgtaa acactgtaca atcccttaaa tgctgcttcg cgcacccttc
    46981 gatccgtgct ttctagcaac tgaccataca cgccatgaga taattggact atttcaccat
    47041 tttctccttc aatcgttgga aaaactagat ctgcattatt caaaacagca aatgtatcac
    47101 ttgaagcatc aaagatttca cctgctccag caagaagaga ttcctgctca gcagataaga
    47161 catgggctcg attatctact atttgctgga tataatggcg atagacttcc aattttggtt
    47221 cttctttgaa atattgccaa atctggtcat ctgacaattg caatatttct ggttcaaacc
    47281 aggaaacggc ttcactaact ttcgaaaaca gactgcttgc tcttgcataa agcgcttggt
    47341 aatctgtatt tccagtgtct tgatcgtttt taaggtgcgc atatacataa atgacttcag
    47401 tttggcgata aaccctcaat acgaattcaa tcgcatttaa aaattgagaa gcgccttgat
    47461 caagtgttcc tttgtgtttt tcagattgtt ttaactcttc tgataattcc aaatatttct
    47521 catcaaactc ttggtcgctt gaaaagatct tggtcaagtc ccaagttaaa ttttcaggca
    47581 attcttctcg ttttggcaac tgctttactt ccatgaaatc cactcctttt cttcccttag
    47641 ctctatctat caaaatagat catagtctaa catccacatg tcacagcatc taacttttct
    47701 actcattcat gtgtctgctt ccatcaattt tagcataact aaatcttgtt ttacatagaa
    47761 aaccgattcc tagcctattt ttatacttac tattttttca aagaagacaa gtgtatgcat
    47821 tcgttaaaaa actgctgata gaccatctct tcatcaatca taggaaaaag ccattccctt
    47881 ttatgttctt ttatttggca aagccatgag ttgaaatcag gaactttctg gttttccaag
    47941 gcttcttcgt acaacattcg ataaagaaaa acctgttctt gtaaataaaa gaaaaaccga
    48001 cttttttgat agatccacga tgatagatgc aaaagatgtt tatgacgcaa gtagcattgt
    48061 tcttgtatgg atactgtatt cttttgcttg tgaataagtt ggcgtgtcag ccatttcttc
    48121 ccatcttcac tcactttttc tatttttttc atttggttca ttttaatttc gttactagtg
    48181 aatatttctt taaggtccct actagaaaaa gtccagcagc tactgcaaaa ggaaatatgc
    48241 cctgatacag tctctgtaat atgatgatac aaataaagct tttgtttctt gagatcagct
    48301 ttccagcaat gcactcctct ttttctatta tagtagcagc aacttttttc tatcaatgag
    48361 aattgcgatt gtccaagaaa agaattacca agtatccacc atacttggta actgttattc
    48421 aaataatttt gggttctttc aataaatctc tggtgagaca gtctagaaca ttggatttct
    48481 attgctagat tcgccaacaa aatatccggc ctttgccgca acctcggcaa ataggcttcc
    48541 aaaaatactg gttctactga ctgtcccagc caatccatga agcattcctt taactgtaag
    48601 tgctcttttg attctctttc actaaagacc gaacagttat ctgatttttg atgggcaaaa
    48661 tgagcacatt ttttctttcc ctttttcaaa atcactcttt ttcgacagcc acgacaataa
    48721 tatttctttc ctttttctgc atgtttagca aaacagcact tattatattc attcattgca
    48781 agcagcattt ttctccctct gaacttattt acgtctaaga atttatttac acgaaaaaag
    48841 agggcgtgaa aaagctattc tgcatcaagt aataagaaca gctaaacaaa aatagttccc
    48901 aatatttttc gtttggttgg gcttgttacc gcagatgcaa gcttttgaac acatttatac
    48961 gaaaaaaaga ctgcgacaca atttttgtca cagtctctta ctataatgct gatttataca
    49021 aaataaaatt tcgttcgctc gatagcatta cgcgccatca gacattgtcc atattcattc
    49081 aatgtttctg gtgtacgatc gctcttttca gcaaactcca aaattcgagc aatctgattc
    49141 tctacatccg cttggttgag attttccatc cagaagtgaa cgactaggta atagcgctct
    49201 tcgaataaat acaaatcagt ccaagcagac tctagttcga catctgttgc aagttggatc
    49261 acttgttcaa aatcttcaaa agcaaaagtt gcttgtcttt cctgttcttc tagggcgctt
    49321 ccagataatt cttcctccgg atcgctgcca ataatctgct gacgaagaaa gtcactcaca
    49381 tcttctgaat caacagtaga atcttctgat tgagaaattt cttcatccgg aagattttta
    49441 ctgataaaca gttctaatcc gtctcctttt ggcaaaactt ggaaagtgac agcttcgctt
    49501 cctcggaact cctcttcgat atcaacttct tccaaaatac tataaaagaa attttcgatt
    49561 tctttgtgat tgccaagtaa atccaaaaat gaaacgcccc gttcctctaa atcttcatga
    49621 ccaattagta cacggatcgt attttcatta atatgttcca tttccatttt gctacacctc
    49681 actttgccac aatgtttaat atagattcat tgtagcgaaa tcagcttaaa tgtaaagaaa
    49741 aaaaatctcg ctgttaagcg aatttaataa aaccagcgga tttttcaacc tttcaagcta
    49801 tcttatttaa ctataacatt tttggcagac gaatactata tagccgactt ttcagctaat
    49861 tttccctctc tatttttcgt gcaatcatca tcttctacta cctttttata catctaatca
    49921 agaatacttt ttgtaaaaac aaaaaaactt ggaaaaacta tctttgtaat agtcttt
//
LOCUS       DAZKCH010000010        45849 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000010 DAZKCH010000000
VERSION     DAZKCH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.010"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            54..1124
                     /locus_tag="ACG84X_000622"
     CDS             54..1124
                     /locus_tag="ACG84X_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126523.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            1139..1807
                     /locus_tag="ACG84X_000623"
     CDS             1139..1807
                     /locus_tag="ACG84X_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126524.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            1827..2405
                     /locus_tag="ACG84X_000624"
     CDS             1827..2405
                     /locus_tag="ACG84X_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9126525.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            2806..3717
                     /locus_tag="ACG84X_000625"
     CDS             2806..3717
                     /locus_tag="ACG84X_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFP9126526.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(4095..5012)
                     /gene="rnhC"
                     /locus_tag="ACG84X_000626"
     CDS             complement(4095..5012)
                     /gene="rnhC"
                     /locus_tag="ACG84X_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFP9126527.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            5214..5651
                     /gene="zapA"
                     /locus_tag="ACG84X_000627"
     CDS             5214..5651
                     /gene="zapA"
                     /locus_tag="ACG84X_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFP9126528.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            5709..6257
                     /locus_tag="ACG84X_000628"
     CDS             5709..6257
                     /locus_tag="ACG84X_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFP9126529.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            6372..8732
                     /locus_tag="ACG84X_000629"
     CDS             6372..8732
                     /locus_tag="ACG84X_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFP9126530.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            8819..9133
                     /gene="trxA"
                     /locus_tag="ACG84X_000630"
     CDS             8819..9133
                     /gene="trxA"
                     /locus_tag="ACG84X_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFP9126531.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            9315..11093
                     /gene="uvrC"
                     /locus_tag="ACG84X_000631"
     CDS             9315..11093
                     /gene="uvrC"
                     /locus_tag="ACG84X_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFP9126532.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTCQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            11238..12137
                     /locus_tag="ACG84X_000632"
     CDS             11238..12137
                     /locus_tag="ACG84X_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126533.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            12130..13392
                     /locus_tag="ACG84X_000633"
     CDS             12130..13392
                     /locus_tag="ACG84X_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126534.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            13553..15451
                     /locus_tag="ACG84X_000634"
     CDS             13553..15451
                     /locus_tag="ACG84X_000634"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFP9126535.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(15781..16500)
                     /locus_tag="ACG84X_000635"
     CDS             complement(15781..16500)
                     /locus_tag="ACG84X_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFP9126536.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    16690..16737
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            16837..17169
                     /locus_tag="ACG84X_000636"
     CDS             16837..17169
                     /locus_tag="ACG84X_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126537.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            17156..19159
                     /locus_tag="ACG84X_000637"
     CDS             17156..19159
                     /locus_tag="ACG84X_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFP9126538.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            19178..19648
                     /locus_tag="ACG84X_000638"
     CDS             19178..19648
                     /locus_tag="ACG84X_000638"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFP9126539.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            19669..20253
                     /locus_tag="ACG84X_000639"
     CDS             19669..20253
                     /locus_tag="ACG84X_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFP9126540.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            20268..21254
                     /locus_tag="ACG84X_000640"
     CDS             20268..21254
                     /locus_tag="ACG84X_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFP9126541.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            21244..21555
                     /locus_tag="ACG84X_000641"
     CDS             21244..21555
                     /locus_tag="ACG84X_000641"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFP9126542.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            21577..23358
                     /locus_tag="ACG84X_000642"
     CDS             21577..23358
                     /locus_tag="ACG84X_000642"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFP9126543.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            23351..24727
                     /locus_tag="ACG84X_000643"
     CDS             23351..24727
                     /locus_tag="ACG84X_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFP9126544.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            24734..25369
                     /locus_tag="ACG84X_000644"
     CDS             24734..25369
                     /locus_tag="ACG84X_000644"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFP9126545.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            25399..26754
                     /locus_tag="ACG84X_000645"
     CDS             25399..26754
                     /locus_tag="ACG84X_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFP9126546.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(26946..28340)
                     /locus_tag="ACG84X_000646"
     CDS             complement(26946..28340)
                     /locus_tag="ACG84X_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFP9126547.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            28432..29403
                     /locus_tag="ACG84X_000647"
     CDS             28432..29403
                     /locus_tag="ACG84X_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFP9126548.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            29400..30182
                     /locus_tag="ACG84X_000648"
     CDS             29400..30182
                     /locus_tag="ACG84X_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFP9126549.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(30351..30722)
                     /locus_tag="ACG84X_000649"
     CDS             complement(30351..30722)
                     /locus_tag="ACG84X_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9126550.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            30856..31299
                     /locus_tag="ACG84X_000650"
     CDS             30856..31299
                     /locus_tag="ACG84X_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFP9126551.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(31342..32151)
                     /gene="yidA"
                     /locus_tag="ACG84X_000651"
     CDS             complement(31342..32151)
                     /gene="yidA"
                     /locus_tag="ACG84X_000651"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFP9126552.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(32170..33537)
                     /locus_tag="ACG84X_000652"
     CDS             complement(32170..33537)
                     /locus_tag="ACG84X_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFP9126553.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(33521..34351)
                     /locus_tag="ACG84X_000653"
     CDS             complement(33521..34351)
                     /locus_tag="ACG84X_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFP9126554.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            34514..34951
                     /locus_tag="ACG84X_000654"
     CDS             34514..34951
                     /locus_tag="ACG84X_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFP9126555.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            35027..35647
                     /gene="rpoE"
                     /locus_tag="ACG84X_000655"
     CDS             35027..35647
                     /gene="rpoE"
                     /locus_tag="ACG84X_000655"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFP9126556.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            35836..36342
                     /locus_tag="ACG84X_000656"
     CDS             35836..36342
                     /locus_tag="ACG84X_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFP9126557.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            36359..37258
                     /locus_tag="ACG84X_000657"
     CDS             36359..37258
                     /locus_tag="ACG84X_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFP9126558.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            37345..38229
                     /locus_tag="ACG84X_000658"
     CDS             37345..38229
                     /locus_tag="ACG84X_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFP9126559.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(38421..38492)
                     /locus_tag="ACG84X_000659"
     tRNA            complement(38421..38492)
                     /locus_tag="ACG84X_000659"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(38457..38459),aa:Arg,seq:ccg)
     gene            38552..39886
                     /gene="rpoN"
                     /locus_tag="ACG84X_000660"
     CDS             38552..39886
                     /gene="rpoN"
                     /locus_tag="ACG84X_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFP9126560.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            40035..41126
                     /locus_tag="ACG84X_000661"
     CDS             40035..41126
                     /locus_tag="ACG84X_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFP9126561.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            41167..42168
                     /gene="gap"
                     /locus_tag="ACG84X_000662"
     CDS             41167..42168
                     /gene="gap"
                     /locus_tag="ACG84X_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFP9126562.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            42278..43468
                     /gene="pgk"
                     /locus_tag="ACG84X_000663"
     CDS             42278..43468
                     /gene="pgk"
                     /locus_tag="ACG84X_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFP9126563.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            43572..44327
                     /gene="tpiA"
                     /locus_tag="ACG84X_000664"
     CDS             43572..44327
                     /gene="tpiA"
                     /locus_tag="ACG84X_000664"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFP9126564.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            44443..45741
                     /gene="eno"
                     /locus_tag="ACG84X_000665"
     CDS             44443..45741
                     /gene="eno"
                     /locus_tag="ACG84X_000665"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFP9126565.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        15210 a         7928 c         9781 g        12930 t
ORIGIN      
        1 tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt taaatgtttt
       61 tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca ggggtgatgt
      121 ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta gctcaagata
      181 atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa gatgcaaatt
      241 caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa ggtgggaaag
      301 tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca gaagaaggaa
      361 aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc aatcttgttg
      421 aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg aaagaagaat
      481 atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg tttaaactaa
      541 ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca accatcaatg
      601 cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg attaacgcaa
      661 tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc aaaatttcta
      721 aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga tttatgatcg
      781 gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta ctgacgatgc
      841 aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga tttattgcgc
      901 gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt ggtctattag
      961 gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc aattggctgt
     1021 tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca ctattttctg
     1081 ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga ggaagaacat
     1141 gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc aagtagttaa
     1201 agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa tcatcggtcc
     1261 ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga cgcctagcag
     1321 tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg aacgcgttaa
     1381 actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc cttttctgac
     1441 agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc aaaaagaagc
     1501 aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc cagaagaact
     1561 atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg atccgtccat
     1621 tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag aagtagtcga
     1681 tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta ctcacgatac
     1741 acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat tgaaagaaaa
     1801 agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat acacagcaaa
     1861 aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc acttcaacaa
     1921 gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat ttcggtgata
     1981 aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga aaagctttga
     2041 gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa atggcgcagt
     2101 ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt gaaagcaatc
     2161 tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat cgtgaacctt
     2221 ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca aaagaaatcg
     2281 cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa agacctgtgg
     2341 aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta ttaggagaag
     2401 cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat gacgaagatc
     2461 gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt tattctctca
     2521 tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt tttaatttaa
     2581 taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta gatgaatcac
     2641 cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc attttagcag
     2701 taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact taagctgatt
     2761 ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa aaaaataatt
     2821 ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga tgtttttggt
     2881 caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac aaagacaaag
     2941 gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa tgaccgtaca
     3001 ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg agagctggcg
     3061 gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg ctatactgga
     3121 tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa accggaagag
     3181 ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac tggggcatta
     3241 agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat aaaagtaaaa
     3301 aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga tgaattagta
     3361 cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt tatcagttta
     3421 cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata ttattactat
     3481 ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct gcctctggat
     3541 tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca accttctatt
     3601 ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt aacagacagt
     3661 tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt tcagtaataa
     3721 ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg cttattatcg
     3781 cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg ttcaactctg
     3841 agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt gtgacttgtg
     3901 accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca acgttttgtt
     3961 ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt tgttgagcta
     4021 ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt gacatgactt
     4081 ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt ggcaaaatga
     4141 agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt tgccgctact
     4201 tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc tgatgctttg
     4261 tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac agctaaatga
     4321 tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt ttctaaacgc
     4381 gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc ttctggtttt
     4441 tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc gactttcatc
     4501 cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa gacaagcagt
     4561 ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct atcttttaac
     4621 tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg tttcacataa
     4681 gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc actacctaaa
     4741 acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg cttggcttgt
     4801 ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc ttgaaacatc
     4861 acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc aaagctagta
     4921 taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg actaagttgg
     4981 tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt atacataaaa
     5041 ctataccgca actcacgact tttcgttttc taagagattg cgagacatag cattttttta
     5101 aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg tgaaagaacc
     5161 aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt cgtatggcgc
     5221 acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt atcggacggg
     5281 aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta gcagaattga
     5341 aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct gtcaatgcgc
     5401 tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa acagcagaat
     5461 taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc attgaagcaa
     5521 tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat accattaaaa
     5581 atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt aaacaaaaat
     5641 cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag aagagaaagg
     5701 aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt ttttctggag
     5761 cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg tcatttattg
     5821 ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt ccatacccag
     5881 ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt cacctagatg
     5941 aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg ctgcttaccc
     6001 gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga caggtagact
     6061 ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt ttgattttgc
     6121 agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag catagtttcg
     6181 ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag ctttgggtaa
     6241 cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg tacagagtag
     6301 tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat agtgaaagat
     6361 aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa gtcaaacaga
     6421 tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa ttggtaccag
     6481 tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga ttgaaagtgc
     6541 aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc catatgaaac
     6601 ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc agagtattgt
     6661 ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa atcgaatttg
     6721 cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc cgccgtttaa
     6781 aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag ttaaagagca
     6841 taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat gggatcgtcc
     6901 gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat gaccgctacg
     6961 ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac gatcaaagtg
     7021 cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat aatcgtttgc
     7081 gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa ctttctgctg
     7141 aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt aaaatggatc
     7201 tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg ggaatcagtg
     7261 aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag gaaaaagtag
     7321 tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca ggacctaaca
     7381 caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg gggcaagcag
     7441 gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa gtatttgcgg
     7501 atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct catatgacga
     7561 acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt gacgagctcg
     7621 gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta gatgatcttg
     7681 gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa gtttatggat
     7741 ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca ttaagtccaa
     7801 cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc tctagccgat
     7861 taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat gagagccaag
     7921 atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag accgaatatc
     7981 tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg aaagaagctt
     8041 acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa aaagcaaatg
     8101 aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt cgtaaaatgc
     8161 aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca aagacccaat
     8221 tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag aaggcgaaag
     8281 aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc caaagaggga
     8341 cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta aaaatgaatg
     8401 tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa cgagttatcc
     8461 atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt cgaggaaaac
     8521 gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt ctagctggtt
     8581 atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag ggaattactg
     8641 attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca aaccaaggcg
     8701 gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc agatggttcg
     8761 ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg tctttgatat
     8821 gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac ttgtattgat
     8881 tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt tggatcagtt
     8941 ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg atgaaaatcc
     9001 agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga aaaaagatgg
     9061 tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc aaatgatcga
     9121 tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa tccagttccg
     9181 tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt gagtataatt
     9241 acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta attgaatatg
     9301 aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt cctgatcagc
     9361 ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc aaagccaaaa
     9421 tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa acggaacggc
     9481 ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc gaagcattgc
     9541 tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg ttaaaggatg
     9601 ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg gtgattactc
     9661 gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc ggtgcggcga
     9721 atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa cctagtcaga
     9781 cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat tatttcgacg
     9841 tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta aacggaggac
     9901 acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa aacatggagt
     9961 ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc atgacttgcc
    10021 aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg attgataaag
    10081 gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa cgagatgttt
    10141 caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc ggtcagtttt
    10201 atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg atcgacaagc
    10261 ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga gaaaagaaaa
    10321 aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg tttgatctga
    10381 ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac gcgatgaata
    10441 tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg acgaatcctg
    10501 tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat cggaaatata
    10561 aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc atctatcgca
    10621 gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg atcgatggag
    10681 gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga atcgatattc
    10741 ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta ttcggtacag
    10801 atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc cagcgaatcc
    10861 aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt aaaaacagtt
    10921 ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa atgctgctta
    10981 aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta caagaaatcg
    11041 gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa tgaggaaagg
    11101 gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa gagcgtttac
    11161 gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat gtgatttctt
    11221 gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt gggaactaca
    11281 cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg ctaattggcc
    11341 aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg acacaagacc
    11401 aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat gtcatcggtt
    11461 atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa ctgctttatt
    11521 ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac ttttggatgg
    11581 aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct aaaggaaatc
    11641 agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc attttggatg
    11701 agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga atattggaat
    11761 tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat gtagaaaaaa
    11821 tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga aaagtacatg
    11881 agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta agccaacagg
    11941 aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat acgttagaga
    12001 ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact cagttcggct
    12061 acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa ttgaaagcag
    12121 gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa aaatgttaag
    12181 tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat catttatgta
    12241 gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt ggctgataat
    12301 gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt caaagcagtt
    12361 gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc gtatttagta
    12421 gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc attaggacaa
    12481 agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct tcgagcgagt
    12541 caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag tttgactcga
    12601 caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa ctcgacagtc
    12661 caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt gacgtatgcg
    12721 cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga agtgatcctg
    12781 tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt acttgttgca
    12841 ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca attcaaagat
    12901 atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat tggaccattc
    12961 ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt tttagcagct
    13021 ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt gccagtgact
    13081 tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga tccaaacaat
    13141 atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat gccgattcgc
    13201 ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt acttgtagcc
    13261 gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt actcgtttat
    13321 agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag gaatgaacga
    13381 aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt gttcccagct
    13441 tctttttgta tagacctatt ttatttattt tactatattg gatatatatt cattgaaaat
    13501 agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt taatggaccg
    13561 ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca cggaaatcat
    13621 caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga gtgatataca
    13681 tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc ttaaagaaaa
    13741 gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat tcactatttt
    13801 tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag ataaatcgca
    13861 gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata cccggtcaaa
    13921 agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct tgtatatcga
    13981 tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac ttgttttgat
    14041 gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat ctgtcatcga
    14101 tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca aagtgatgga
    14161 tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata ttttgtggat
    14221 tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg cagcacgcta
    14281 taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat tgttttcttt
    14341 tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta aaaatctatc
    14401 cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc ttcaattcaa
    14461 atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc gtaaattgct
    14521 ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct atgagttgaa
    14581 aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg aagaggaaca
    14641 aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc aaaaacatat
    14701 gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg tgctgtttca
    14761 tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag accaatctta
    14821 tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg caaaagatct
    14881 gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg ggccattttc
    14941 gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca cagagcctca
    15001 tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt ggttcagtga
    15061 aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta atgggcacac
    15121 gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag tatttgtcat
    15181 tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt attcactatt
    15241 atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta ttgaacaaca
    15301 atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc aactaccacg
    15361 caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta cccagctcaa
    15421 aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat tgttccatag
    15481 actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac ggtgttcttc
    15541 tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg ttttttgaaa
    15601 ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat aaacggtgtt
    15661 caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa gccattttca
    15721 caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc agaaagtcta
    15781 ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta cacggtgggt
    15841 aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc tttgaaccgc
    15901 ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa gatctttgac
    15961 tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc ttaacaaact
    16021 gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct gttgttcatg
    16081 ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt ccaaaacgac
    16141 attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt tcaatgcttc
    16201 caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta gctttggatg
    16261 aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa taagtttgtc
    16321 gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa taagaggcaa
    16381 tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca cttgatttcc
    16441 ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga ttggtttcat
    16501 ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt aaactatgta
    16561 agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga gaaatttcgt
    16621 gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa aagtaagcag
    16681 aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg agaaggacat
    16741 tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt tcaatgaaaa
    16801 aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt agaagctttg
    16861 gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact gcggcagcag
    16921 ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac aaactatcga
    16981 caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga attagaaaaa
    17041 gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa agatcaatat
    17101 caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga aacttatggc
    17161 cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg agaggatttt
    17221 acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa atagaacaaa
    17281 caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag aagcaaaatt
    17341 aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca tacaacacca
    17401 cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct tacaagattt
    17461 ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc ttgatttaaa
    17521 agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg aagaatggct
    17581 tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga cgaccatttt
    17641 tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac tgagtaagct
    17701 tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc tttcgtatgt
    17761 tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg ggttcaataa
    17821 agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca agcagcaatt
    17881 atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt gcagtggcta
    17941 tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac gagaaaaaat
    18001 aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg tagatgcaga
    18061 agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag atatatacgt
    18121 cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta aattgaaaaa
    18181 ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc caaaatatga
    18241 agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg ggatgatggt
    18301 cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc aaaaactact
    18361 tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct cgataccatc
    18421 gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa aagaactgtt
    18481 tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata cgattttgat
    18541 tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg cagcaaagga
    18601 aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct ggcaagggat
    18661 cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata cagcatttgt
    18721 ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg ttccgattat
    18781 ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt acggactgac
    18841 cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta tttcaggcgg
    18901 aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg ctcgattcag
    18961 tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga cactgctaag
    19021 tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt tttatacagg
    19081 aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca tcaatcacaa
    19141 gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact taattagtca
    19201 aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt tttcagggat
    19261 cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga caacaagtca
    19321 acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc aaggtttgta
    19381 tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt cagttgtaca
    19441 aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt tttcaggtat
    19501 tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac ctgaacatgc
    19561 tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag gtttcgttat
    19621 ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat gaacgccatt
    19681 gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc gttagaacaa
    19741 gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt tgaaacagaa
    19801 catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg tcagctaagg
    19861 aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga atttttaaga
    19921 cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga acaaatccag
    19981 tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt cattgctgga
    20041 gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa tgaacttccc
    20101 tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct gataaacgat
    20161 caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca aggaacgatg
    20221 agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg gaataccacg
    20281 aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag acatttgaac
    20341 ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc acgatttaca
    20401 gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta aaggagcaga
    20461 gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt tggatctata
    20521 cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg acaaatcaaa
    20581 atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg aaggatgcca
    20641 ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata cgagaagtac
    20701 gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat gatcgacagt
    20761 ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg ctgacagaag
    20821 tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata ttgcagaaaa
    20881 gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa aaagaagtat
    20941 ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta gagacagatt
    21001 atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta aagcttgaac
    21061 agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag gctttcggac
    21121 cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac cttcgtttac
    21181 tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg gtgagacaag
    21241 tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc attcaaattg
    21301 tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc aattgaagaa
    21361 atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc attgagccca
    21421 gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat tcccaatcat
    21481 caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa agcagtaggt
    21541 caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa aatcataaaa
    21601 gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca agacatgtgt
    21661 ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga tgtggcgtct
    21721 attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg ctctactggt
    21781 gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga cggaatccaa
    21841 cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg cggagttcaa
    21901 ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga agccggagaa
    21961 acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat aaaacataaa
    22021 atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg ttcattcact
    22081 attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt gacgatgctt
    22141 caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc ggatgcaccc
    22201 atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg aggagcagca
    22261 gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat tgcaaaatgg
    22321 gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga gatgacggat
    22381 gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt gatggaacgt
    22441 acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc ttctatctat
    22501 acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc tatcatggca
    22561 gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt ggaagaaatg
    22621 cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata ctatgaacga
    22681 tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac cgcaatcagt
    22741 gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac attgcgggtc
    22801 gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt tccttcgatc
    22861 gattggatac aaagctattc tctttattca acagaagtag ggaagtatat ggatcatatc
    22921 cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca ggaagaacag
    22981 cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa tgaccgtctg
    23041 acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc ttttgatgat
    23101 gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat cttgaccttt
    23161 ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat catggacggt
    23221 accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac agaattagaa
    23281 aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt ttcagaagga
    23341 ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc cattgatggc
    23401 ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta tgcaaaatgg
    23461 cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg tccaaatatt
    23521 cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag gccatccttt
    23581 agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg gacgaccgaa
    23641 agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag aagtaatcaa
    23701 tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg caatcgatca
    23761 tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg gtcttcctca
    23821 taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat cagatgattt
    23881 cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt tcatggaaga
    23941 ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag caaacgaccc
    24001 tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat atcttgctta
    24061 tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg cagaggcatt
    24121 gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc ctgggtatct
    24181 ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac taaaaggatc
    24241 ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc caatccctga
    24301 cttgactggt tatattacag aaggacagat catcttgact agagagcttt acaagagtgg
    24361 gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata agggaactgg
    24421 acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg cagcctatgc
    24481 acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt tatctgatgt
    24541 agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca atcaaggatt
    24601 ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc tatcgatgtt
    24661 gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc tgccagaagg
    24721 gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat tgactcgatt
    24781 gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata agcaagatga
    24841 actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc aagaaatgga
    24901 agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga tcacggaacc
    24961 tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta tcgtagacaa
    25021 aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac agctgacaga
    25081 cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt caatcgatcg
    25141 gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa cttgtcaact
    25201 gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat atatgacgat
    25261 ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa acgagcgcgc
    25321 agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag tggtatcttt
    25381 ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg tttgccggct
    25441 gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg cctacttacc
    25501 ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct tttcactgca
    25561 acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca ttggaacagt
    25621 gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt tatgatggtt
    25681 ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg tattatatta
    25741 aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct ttacatccta
    25801 aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt atttgtgcct
    25861 gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc tagtttttgt
    25921 aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa tgtttatttg
    25981 atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt atggcgtgat
    26041 ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc attaaccgtt
    26101 acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg caatggggca
    26161 acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat gagtgtgaca
    26221 cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc aggtctgatt
    26281 ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg cggattgaaa
    26341 acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg acgtacgaga
    26401 gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact tactttattt
    26461 tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac tgaaacgata
    26521 cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt tggtacagta
    26581 ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat cattatagcg
    26641 cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat gacaaaagca
    26701 caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg ataatttcat
    26761 cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt ttcttgcttc
    26821 ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg ttgttgaacc
    26881 tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct ttatttatca
    26941 ataggttata attcatattt ttttattttt tcttttacga tacttagtcc agaagctaaa
    27001 atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg cgcacgtgta
    27061 gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt ctcaattatc
    27121 ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg attcgttggt
    27181 ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag acttaattta
    27241 gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac ttccacatct
    27301 aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct ttggacatgt
    27361 actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt cattccagct
    27421 aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt atgttgatag
    27481 taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc tttttcaatc
    27541 acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg attattacaa
    27601 gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat caatatatca
    27661 ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata taactgagcc
    27721 aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc tggagagaaa
    27781 agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga tagagattct
    27841 aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa ttgaaaattt
    27901 gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt actagttgat
    27961 tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag accaaaatca
    28021 atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac attgggagaa
    28081 ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc atatttataa
    28141 gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct ttgggagggt
    28201 aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg ttgaatcaac
    28261 gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa cgggtaattg
    28321 tcataagaat taataggcat tttctccact ccttaaaatt gtataccata caattttacc
    28381 attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc tatgaaaatt
    28441 attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca agtaatgaaa
    28501 aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt ggtggaaatt
    28561 ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt gggggagaac
    28621 agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta tcatttacct
    28681 tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa agcattgata
    28741 aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc aacagattac
    28801 ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca agcattgtcg
    28861 catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta cgatatttta
    28921 gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa aataacgttt
    28981 ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg tacgttgacc
    29041 tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca tatcaatgct
    29101 gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga aacttctcaa
    29161 atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct tatagccatg
    29221 gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt agtttctgag
    29281 aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt tggtctagct
    29341 attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg ggctttaaaa
    29401 tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa ggaaatccag
    29461 cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa attgccattg
    29521 aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt gagcttagat
    29581 ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca acagcatttg
    29641 ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact caaagcggta
    29701 atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt attatgccga
    29761 aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt aaagaagcct
    29821 acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct aaattgcagc
    29881 cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg acagcagaaa
    29941 gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc aatgaagatc
    30001 cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga atgaataaaa
    30061 caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt gaattaaaag
    30121 aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc tcgtttattt
    30181 gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta tagctacaat
    30241 ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt ctcattttaa
    30301 ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa ctatcctcgg
    30361 atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg cgcagtgcca
    30421 ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc gtgtaatttt
    30481 tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc atacgcacca
    30541 tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt caaataaaca
    30601 agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc aaatgccttt
    30661 tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg agccattttc
    30721 atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta aggaaatagt
    30781 tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat aaaactgtta
    30841 aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt tgctgattat
    30901 caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc agtaatcgag
    30961 gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga gacgaaagaa
    31021 gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat ttcttcttat
    31081 ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta ttataatcca
    31141 ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga aaagaccaat
    31201 aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg tagccaccga
    31261 tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag tagatcagct
    31321 ttctctcagt ttttttattt attacagtac atattttttg attgcttcag ctacaccgtg
    31381 ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa cggcatttcc
    31441 cattgctact cctagaccag catattcaat catggataag tcgttctcgt tatctccgat
    31501 agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa ctgccgcacc
    31561 tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga ccgttgtgta
    31621 tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt ctggttcgtc
    31681 gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg ttcgatattt
    31741 tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat ctcgattagg
    31801 cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc gtgccattac
    31861 ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt tacctgattt
    31921 cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt gaaaaaggtt
    31981 caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata aaacgatcga
    32041 aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta cttctctttt
    32101 ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca taatttcctc
    32161 caatatattt taatttattt caatcaatgc gccattacgg atatggctgg caaattcttg
    32221 ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca tttcttttgg
    32281 aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa gctgactaac
    32341 ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg tgcgatgtct
    32401 gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca cagcagtgta
    32461 ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga ctaattttga
    32521 atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa aacgtttagc
    32581 taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag tgcccaagac
    32641 cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa atggcagaag
    32701 taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt gtgcgcgatg
    32761 aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt acacttgcac
    32821 atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac tcatggaaaa
    32881 agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat caaatgttcc
    32941 atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat ctgcatcgat
    33001 ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga tcacactagc
    33061 taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt ctgtttctgg
    33121 agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat gttcaaatgt
    33181 atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag tcaccagccg
    33241 ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc gagaaaagat
    33301 atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac ggctatgttc
    33361 tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta gacgttggac
    33421 ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat agttatggac
    33481 tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg ttgtcataat
    33541 gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc cattgctcca
    33601 gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca gaatacagct
    33661 tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt tggtcaagca
    33721 gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt gtaccaaagt
    33781 cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt tcctgattac
    33841 cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc tgagcgatac
    33901 cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa gaatgggtga
    33961 tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg agcatttgct
    34021 cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc aaagaaatat
    34081 tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc actggagcgt
    34141 aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga acatccttca
    34201 tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc tggtgttctt
    34261 tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt ttttgataaa
    34321 tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat aaattcatat
    34381 tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt tttctgtaaa
    34441 aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta tgagaagtaa
    34501 aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat tgcgtacaaa
    34561 agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc aaatggtgac
    34621 aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg gcgatgagat
    34681 tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg caggagaaat
    34741 gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc gaacaccata
    34801 cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga aagaccgtcc
    34861 cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa aaatcggcga
    34921 atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga ttttttgtgt
    34981 ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg aaattagtgt
    35041 atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg cgatcttaga
    35101 acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa actatcttgg
    35161 gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact tgaatattga
    35221 cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt atgctatcga
    35281 ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata ctccacgtcg
    35341 ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga tcgattacaa
    35401 tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc tgtttgatga
    35461 cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag aaatcggagc
    35521 agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag atttaagtat
    35581 catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg actctgaaaa
    35641 agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct atcagaataa
    35701 ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc ccaagtaaat
    35761 acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat taagtgaggc
    35821 agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat cgaaaaatac
    35881 cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg tatcacgatg
    35941 aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt tcataaagcc
    36001 ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt ttatcggata
    36061 ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt ggacttattt
    36121 gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga gctccatatg
    36181 attttagata aaatagacag tccggaaaaa gagattctga tcctctactt ttttgaagga
    36241 tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt taaaacgaaa
    36301 atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga agagtgccat
    36361 gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac aagcaattcc
    36421 caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat catttataaa
    36481 agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta tcgtaatgat
    36541 tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag atttacccat
    36601 cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat ctgaaaaaat
    36661 cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa caattcatgg
    36721 attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg aaaaagaata
    36781 tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa tcgtagacga
    36841 taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata gccatgttga
    36901 aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc cacttttatt
    36961 caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga tggccgaaca
    37021 agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag aagggacgat
    37081 agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag agcatcaatt
    37141 agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac cagaatttgt
    37201 cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg atcattagac
    37261 gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa taataagaag
    37321 agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag tattattgct
    37381 ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac cgaagtaaaa
    37441 ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga acaatcaacc
    37501 attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga atcagcggaa
    37561 aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag ccgagatccg
    37621 gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac aacaccgcag
    37681 cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt aggagaaaat
    37741 acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga gattggcaat
    37801 cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac ggaggaagtg
    37861 acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt tgttcgtccg
    37921 ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat catcgaatgg
    37981 tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca gaagatccaa
    38041 gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga aacgattcgt
    38101 gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac gacagttggg
    38161 gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga tcatcggcca
    38221 gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt agttgaacac
    38281 ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa aaaactgtcc
    38341 accaattttc tttggcggac agttttcact taaaaataaa gaagcaacta ttcgtaaatt
    38401 atgctaaaat agcagtagaa cgcgtcctga gggaatcgaa cccccgtctc aagaaccgga
    38461 atcttacgtg atatccacta cactaaggac gcaagcactg ggataattgt aactaaacag
    38521 ataaaaaatt acaaggggat tggacaaaaa aatgaaattt gagcaaaatt tttcacaaaa
    38581 acagcagcag acacagaaac tagccatgac gcaacagttg caacagtcca tccaagtttt
    38641 acaatataac agtgaggagc tgttggcatt cgttgagaat caagcaatgg aaaatccatt
    38701 ggtggaagtt gttgagccgg aatggcagcc agattacata aaagcttctt catcttctta
    38761 tgaaggagaa gagacaaatt acctaaatca gattcctgat acaaaagggt ctttatttga
    38821 ttcattgatc gaacaagtcc atttgaatta ccgagatact tttttgagga aaatcgttct
    38881 ttatcttgta gaatacatcg atttgaacgg atttttgacg attagtttag aagaagccgg
    38941 aaaagagatt ggagctacgc ctatccaaat gctcgatgcg ttgactctga ttcagcaatt
    39001 agaaccagct ggagtaggtg cacgtagttt gcaagaatgt ctcatgcttc aaacagaacg
    39061 agatgattat gcgccggaat tagcttatat cgtgttggaa gaatgttttg aggaactggt
    39121 ggagcgaaaa tggaaagaaa tcgcacaacg tttttctgtt gatctacatg ctgttcagca
    39181 gatattcgac tatttacaaa cgttgagtcc aagccctggc cggattttcg accgtagcag
    39241 cgaattgtac attattcctg atgtccgggt attagtggac gacgataaaa atgtacaagt
    39301 tatctcaaac cgaaaaaatc agccaaatat acgctttcaa gagagttact tcaaacaaat
    39361 gtcacaacaa gcagataaag aaactgaaaa ttatttaaaa gaacggaaac aggaattcga
    39421 atggttgaag aaaacgatcc tacaacgtgg ggatacaatt ttgcgggttg ctcaagtcat
    39481 tgtttcccgg caaaaagctt tctttatcga caaggaacgt ccaatcaagc ctcttacgtt
    39541 aaaggaagtt gcaactgaga tagatgtgca tgaatccacg gtcagtcgtg cagtcaacgg
    39601 gaaatatttg gaaacagact tcggtgtatt tgaattaaaa aaatttttca ctacacgaat
    39661 tcctacgaat agtacagaac agacagaaga cctttcagca gatacagcga agaaaaagct
    39721 gcaggaatta gtcgatcaag aagacaaaaa caagccgttg tctgaccaga aattggttga
    39781 attgctgaaa aaagatgaga tagcgatctc aagacgaaca gtagcaaaat atcgtgattt
    39841 attaggaatc ccgagttcat caaaaagaaa acgttatgat aactaatcag tcaaaagact
    39901 agaaaaagta tttcactttt tctagtcttt ttagttgaaa aacgagagca aaactgttag
    39961 acttacagtc gtgaggttga gatttccctt tattgatgtg aaattcgaat agttaatttc
    40021 tttttttatc gtatatgggt cgttttaagt ctacattgga cgtaaagtgt ccaactaagg
    40081 agatcgctat gctggatgaa ataaaaatga ttgaatctgt tgcaccagat attatcgaag
    40141 tgttgcaaga acgctataaa attttacgaa atatctattg gatgcagccg attggacgtc
    40201 gaagtttatc ggaaagtatg gggatcacag aacgagtatt gcgaacagaa acagatcttt
    40261 tgaaaaatct gaatttgatc gacacctcaa aaagcggtat gacgctgaca actaagggcg
    40321 aagaagttta tcaaagcctt gaaaacttca tggatcagct tttaggtacg catcaaaccg
    40381 aacaacagtt ggcagaatat tttggtaacc aacgctgtat cgttgtttca ggaaacagcg
    40441 aagagcagac caaagtggct gatgcattcg gcgaagcgct gagcgaagcc ctagaccgac
    40501 tacttccaga aggcgagaat atcatcgctg tgatgggagg aactactatg gctgtggtag
    40561 ccgaacaatt gtctaatctg gaaaataaga aacggcataa cctgtttgtc cctgcaagag
    40621 gcgggattgg tgaagcgata actgtacagg caaattctgt cagtgcaaga atggctgcta
    40681 aagcaaacgg taaccaccgt gcactttatg ttccggaaca attaagtctg gcaacttaca
    40741 attctttact caatgagcca tctatccaag aagtcttaaa cttgattagt gaagcgaatt
    40801 gtgttattca tagtattggg cgtgcattac acatggcagc acgtcgtaag atgactgaaa
    40861 aagaattagt catgctgaaa caagcaaatg ctgttgcgga atcttttggc tactttttca
    40921 atgaaaaagg tgaagtcgtt tataaggtcc ctagaatcgg catagaattg caagatttgg
    40981 aaaaagtccc gatcatcatg gcaatcgcgg gcggaaaatc aaaagctaaa gcaattcgag
    41041 cttatatgaa aaatgcacca aaacaaacgt ggctcatcac tgatgaagct gctgcaaatg
    41101 agattttaaa aggggtaacc ctttaaaata aatatttttt tgattttcat aaggaggaaa
    41161 tcttaaatga cagttaaagt aggtattaat ggttttggac gtattggacg tctagcattc
    41221 cgtcgtatcc aagatgtaga tggaatcgaa gtagtagcaa tcaacgactt gacagatgct
    41281 aaaatgttgg cacacttgtt aaaatacgac acaactcaag gacgtttcaa cggaacagtt
    41341 gaagttcatg aaggttcatt caacgtaaac ggaaaagaag ttaaagtatt agctaaccgc
    41401 aacccagaag aattaccatg gggcgaacta ggcgtagata tcgttctaga atgtactggt
    41461 ttcttcactt ctaaatcagc agctgaaaaa catttaacag ctggtgctaa acgcgttgtt
    41521 atctctgctc ctggcggaaa cgatgttcca acaatcgttt ataacacaaa ccacgaaaca
    41581 ttaactggta aagaaacagt tatctcaggt gcttcatgta ctactaactg tttagctcct
    41641 atggctaaaa cattgaacga caaatttggt gttgttgaag gattaatgac aactatccac
    41701 gcttacacag gtgaccaaat gactctagac ggacctcatc ctaaaggtga cttccgccgt
    41761 gcacgcgctg ctgctgcaaa catcgttcct aactcaacag gtgctgctaa agctatcggt
    41821 ttagtaattc ctgaattgaa cggtaaatta gacggagctg ctcaacgtgt tcctgtacca
    41881 acaggttcat taacagaatt agtaacagtt cttgaaaaag aagtaactgt tgacgaaatc
    41941 aatgcagcaa tgaaagaagc ttcaaacgaa tcttacggat acaacacaga cgaaatcgtt
    42001 tcttcagata tcgttggtat gacttacggt tcattatttg atgctacaca aactaaagta
    42061 atgacagttg gcgacaaaca attagttaaa actgttgctt ggtacgacaa cgaaatgtca
    42121 tacactgcac aattagtacg tactttagaa tacttcgcta acttataaga tagacaaacg
    42181 tacaagtgta aattatagac atgtacattt aaaagcgggg aagcaatcgc gcttcttccg
    42241 ctttttttga taataagttt attcaggagg aaataaaatg gctaagaaaa cagtgaaaga
    42301 tatcgattta aaagacaaaa aagttcttgt ccgtgttgac ttcaacgttc ctttgaaaga
    42361 cggcgtgatc actgacgaca ctcgtatcaa agcagcattg ccaacaatca actacgttct
    42421 agaacaaggc ggaaaagcaa tccttttctc tcaccttgga cgtgtaaaaa cagaagaaga
    42481 taaagaagga aaatctttag ctccagttgc aaaacgtcta ggcgaattat taggtaaaga
    42541 agtaacattc gtacctgaaa ctcgcggaga acaattagaa gaagcaatcc gcaacatgaa
    42601 tgacggcgac gttgtcgtat tcgaaaatac acgatttgaa gatattgacg gtaaaaaaga
    42661 aagcaaaaat gatacagaac taggtaaata ctgggcttca ttaggcgatg tatttgttaa
    42721 cgatgctttc ggtacagctc accgtgcaca tgcttctaac gtaggtatcg cttcaactgg
    42781 tatcccaaca gttgctggat tcttgatgga aaaagaaatc aagttcatcg gtgaagcagt
    42841 agaagaacca aaacgaccaa tgattgcaat ccttggtggc gcaaaagttt ctgataaaat
    42901 cggcgtaatc gaaaacttga ttcctaaagc agataaaatc ttgatcggtg gcggaatgac
    42961 ttacacattc tacgaagcaa aaggaatcaa gatcggtaac tctctagtag aagctgataa
    43021 agtggaacta gcaaaagaat taatcgaaaa agcaggcgac aaacttgtct tgccaatcga
    43081 caatgtctgt gcaccagaat tttcaaatga tgttgaaaca caagtaatcg aaggagacat
    43141 tcctgatggt ttgatggctt tagacatcgg cccagcatca gtaaaattat ttgctgatac
    43201 attacaaggt gcaaaaacag ttgtttggaa cggacctatg ggtgtatttg aaatgagtaa
    43261 ctttgctaaa ggtacaatcg gtgtttgtga agcaatcgct aacttagaag gcgcaacaac
    43321 aatcatcggt ggcggagact cagctgcagc agcagaacaa ttaggatttg ctgacaaatt
    43381 cacacacatc tcaacaggtg gtggcgcaag cttggaattg cttgaaggta aagaattacc
    43441 aggactagca gcaatcaacg ataaataaac gaccaagttt gctcaattct gacgagtaat
    43501 cgatcaaaag gtgaagggag ttttcatgac tccctagcca tttttcaata aattaaggag
    43561 tgtgttcctc aatgcgtaaa cctattatcg caggtaactg gaaaatgaac aaaactgcat
    43621 cagaagcaaa agaatttgct gaagcagtaa aaaacaaaat cccttcaaat gacaaagttg
    43681 attcagtcat cggatctcct gcattattct tacaagaatt aatgacatca gctgaaggta
    43741 cagaactaaa aatctcagca caaaactgct actgggaaaa ctcaggtgcg ttcactggtg
    43801 aaacttcacc agcagctctt gctgatctag gtgttcatta tgtgatcatc ggacattcag
    43861 aacgtcgtga atatttccat gaaacagacg aagacatcaa taaaaaagca aaagctatct
    43921 ttgcaaatgg tatgacacca atcctatgct gcggcgaatc tttagaaacc tatgaagcag
    43981 gcaaaactgc tgaatggatc gaaggacaaa ttacagctgg tttagctgat ctttcagctg
    44041 aacaagtgtc aaacatggtt attgcttatg aaccaatctg ggcaatcggt actggtaaat
    44101 cagctgacgc acaaatcgct gacgaaattt gtggagttgt acgtcaaaca gttgaaaaac
    44161 tttatggaaa agaagtatca gaagcagttc gtatccaata cggcggttct gtaaaaccag
    44221 aaaatattgc tgaatacatg gcaaaagaaa atgttgacgg tgctttagtc ggtggcgcaa
    44281 gcttgcaagc agattcattt ttgtcattgt tagacgctgt aaaataattg ttgaaaattt
    44341 gcgaaaaatg caagaaatgt ttgcactaat gagcaaaatt aactaaaatc gtatatgagg
    44401 gaaatccctt aggaaaaaac aaactcaaag gagagacaaa acatgtcaat tattactgat
    44461 gtttacgctc gcgagatctt agactcacgt ggtaacccaa caatcgaagt agaagtatac
    44521 acagaaagcg gagcttttgg ccgcggaatg gttccttcag gtgcttcaac tggtgaatac
    44581 gaagcagttg aattacgtga cggagacaaa gctcgttatg gcggtaaagg tgtaactaaa
    44641 gctgtcgaca acgtaaacaa catcattgct gaagcaatca ttggctacga tgttcgtgac
    44701 caaatggcta tcgacaaagc tatgatcgct ttagacggaa ctcctaacaa aggtaaatta
    44761 ggtgcgaacg ctattttagg tgtttctatc gctgttgcac gtgcagctgc tgactaccta
    44821 gaagtacctt tataccacta cctaggcgga ttcaacacaa aagtattgcc aacaccaatg
    44881 atgaacatca tcaacggcgg atcacatgct gataactcaa tcgacttcca agaattcatg
    44941 atcatgcctg ttggcgctcc aacattcaaa gaagctctac gtatgggtgc tgaagtattc
    45001 cacgcattag cttcaatctt gaaagctcgc ggattagcaa cttctgttgg tgacgaaggt
    45061 ggatttgctc caaaccttgg ttcaaacgaa gaaggttttg aagtaatcat cgaagcaatc
    45121 gaaaaagctg gctatgtacc tggtaaagac gttgttcttg ctatggatgc tgcttcttca
    45181 gaattctacg acaaagaaaa aggtgtttac gtactagctg actcaggcga aggcgaaaaa
    45241 acaactgacg aaatgatcaa attctacgaa gaattagttt ctaaatatcc aatcatctca
    45301 atcgaagatg gattagacga aaacgactgg gacggattca agaaattaac tgacgtatta
    45361 ggcgacaaag ttcaattagt tggtgacgac ttgttcgtaa caaacactca aaaattatct
    45421 gaaggtatcg aaaaaggaat tgctaactca atccttatca aagtgaacca aatcggtaca
    45481 ttaacagaaa ctttcgaagc tatcgaaatg gctaaagaag ctggctacac agcagttgta
    45541 tctcaccgtt ctggtgaaac agaagattca acaatctctg atatcgctgt tgcaacaaat
    45601 gctggccaaa tcaaaactgg ttctctatca cgtactgacc gtattgctaa atacaaccaa
    45661 ttactacgta tcgaagacca acttggtgaa gttgcagaat acaaaggttt gaaatctttc
    45721 tacaacttaa aaaacaaata attcttttct aatgaagata catgatcgac tattgaaaga
    45781 tagtcgagta tgatcactta gttaagtaat cgaactctct acttgctgaa atatcagcag
    45841 gtagagagt
//
LOCUS       DAZKCH010000011        45493 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000011 DAZKCH010000000
VERSION     DAZKCH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.011"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..235
                     /locus_tag="ACG84X_000666"
     CDS             <1..235
                     /locus_tag="ACG84X_000666"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126566.1"
                     /translation="RTVTRLLSQSFFRIQQVKLLRNIQRVKLKIADKRRWKFYVFLLV
                     YAINKLNIQNTIDFNERASINGCVVFICPGRVK"
     gene            435..1625
                     /locus_tag="ACG84X_000667"
     CDS             435..1625
                     /locus_tag="ACG84X_000667"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFP9126567.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            1727..2680
                     /locus_tag="ACG84X_000668"
     CDS             1727..2680
                     /locus_tag="ACG84X_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFP9126568.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            2749..4098
                     /locus_tag="ACG84X_000669"
     CDS             2749..4098
                     /locus_tag="ACG84X_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFP9126569.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(4281..4604)
                     /locus_tag="ACG84X_000670"
     CDS             complement(4281..4604)
                     /locus_tag="ACG84X_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126570.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            4733..5896
                     /locus_tag="ACG84X_000671"
     CDS             4733..5896
                     /locus_tag="ACG84X_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9126571.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            5966..7315
                     /locus_tag="ACG84X_000672"
     CDS             5966..7315
                     /locus_tag="ACG84X_000672"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFP9126572.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(7360..7791)
                     /locus_tag="ACG84X_000673"
     CDS             complement(7360..7791)
                     /locus_tag="ACG84X_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9126573.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            8179..10821
                     /gene="alaS"
                     /locus_tag="ACG84X_000674"
     CDS             8179..10821
                     /gene="alaS"
                     /locus_tag="ACG84X_000674"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFP9126574.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            11021..11617
                     /locus_tag="ACG84X_000675"
     CDS             11021..11617
                     /locus_tag="ACG84X_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFP9126575.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            11739..12887
                     /locus_tag="ACG84X_000676"
     CDS             11739..12887
                     /locus_tag="ACG84X_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFP9126576.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(12925..13338)
                     /locus_tag="ACG84X_000677"
     CDS             complement(12925..13338)
                     /locus_tag="ACG84X_000677"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFP9126577.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            13417..13848
                     /locus_tag="ACG84X_000678"
     CDS             13417..13848
                     /locus_tag="ACG84X_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFP9126578.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(13947..14180)
                     /locus_tag="ACG84X_000679"
     CDS             complement(13947..14180)
                     /locus_tag="ACG84X_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9126579.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            14363..16033
                     /locus_tag="ACG84X_000680"
     CDS             14363..16033
                     /locus_tag="ACG84X_000680"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFP9126580.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            16180..16566
                     /locus_tag="ACG84X_000681"
     CDS             16180..16566
                     /locus_tag="ACG84X_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126581.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            16553..17251
                     /locus_tag="ACG84X_000682"
     CDS             16553..17251
                     /locus_tag="ACG84X_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFP9126582.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            17256..17720
                     /gene="lspA"
                     /locus_tag="ACG84X_000683"
     CDS             17256..17720
                     /gene="lspA"
                     /locus_tag="ACG84X_000683"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFP9126583.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            17717..18628
                     /locus_tag="ACG84X_000684"
     CDS             17717..18628
                     /locus_tag="ACG84X_000684"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFP9126584.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            18863..19402
                     /gene="pyrR"
                     /locus_tag="ACG84X_000685"
     CDS             18863..19402
                     /gene="pyrR"
                     /locus_tag="ACG84X_000685"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFP9126585.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            19416..20699
                     /locus_tag="ACG84X_000686"
     CDS             19416..20699
                     /locus_tag="ACG84X_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFP9126586.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            20712..21638
                     /locus_tag="ACG84X_000687"
     CDS             20712..21638
                     /locus_tag="ACG84X_000687"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFP9126587.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            21657..22937
                     /locus_tag="ACG84X_000688"
     CDS             21657..22937
                     /locus_tag="ACG84X_000688"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFP9126588.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            22942..24018
                     /locus_tag="ACG84X_000689"
     CDS             22942..24018
                     /locus_tag="ACG84X_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFP9126589.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            24023..27208
                     /gene="carB"
                     /locus_tag="ACG84X_000690"
     CDS             24023..27208
                     /gene="carB"
                     /locus_tag="ACG84X_000690"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFP9126590.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            27262..28038
                     /locus_tag="ACG84X_000691"
     CDS             27262..28038
                     /locus_tag="ACG84X_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFP9126591.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            28035..28967
                     /locus_tag="ACG84X_000692"
     CDS             28035..28967
                     /locus_tag="ACG84X_000692"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFP9126592.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            28964..29680
                     /gene="pyrF"
                     /locus_tag="ACG84X_000693"
     CDS             28964..29680
                     /gene="pyrF"
                     /locus_tag="ACG84X_000693"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFP9126593.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            29687..30316
                     /gene="pyrE"
                     /locus_tag="ACG84X_000694"
     CDS             29687..30316
                     /gene="pyrE"
                     /locus_tag="ACG84X_000694"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFP9126594.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            30304..30618
                     /locus_tag="ACG84X_000695"
     CDS             30304..30618
                     /locus_tag="ACG84X_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126595.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            30656..31297
                     /locus_tag="ACG84X_000696"
     CDS             30656..31297
                     /locus_tag="ACG84X_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFP9126596.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            31340..32032
                     /locus_tag="ACG84X_000697"
     CDS             31340..32032
                     /locus_tag="ACG84X_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFP9126597.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            32029..32931
                     /locus_tag="ACG84X_000698"
     CDS             32029..32931
                     /locus_tag="ACG84X_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9126598.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(33089..34795)
                     /gene="efbA"
                     /locus_tag="ACG84X_000699"
     CDS             complement(33089..34795)
                     /gene="efbA"
                     /locus_tag="ACG84X_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFP9126599.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            34985..35608
                     /locus_tag="ACG84X_000700"
     CDS             34985..35608
                     /locus_tag="ACG84X_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126600.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            36058..37107
                     /gene="trpX"
                     /locus_tag="ACG84X_000701"
     CDS             36058..37107
                     /gene="trpX"
                     /locus_tag="ACG84X_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9126601.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            37104..37985
                     /locus_tag="ACG84X_000702"
     CDS             37104..37985
                     /locus_tag="ACG84X_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126602.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            37988..38758
                     /locus_tag="ACG84X_000703"
     CDS             37988..38758
                     /locus_tag="ACG84X_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126603.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            39037..39891
                     /gene="aroE"
                     /locus_tag="ACG84X_000704"
     CDS             39037..39891
                     /gene="aroE"
                     /locus_tag="ACG84X_000704"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFP9126604.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            40069..41232
                     /locus_tag="ACG84X_000705"
     CDS             40069..41232
                     /locus_tag="ACG84X_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFP9126605.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            41349..41759
                     /locus_tag="ACG84X_000706"
     CDS             41349..41759
                     /locus_tag="ACG84X_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9126606.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            41933..44161
                     /gene="topB"
                     /locus_tag="ACG84X_000707"
     CDS             41933..44161
                     /gene="topB"
                     /locus_tag="ACG84X_000707"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFP9126607.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            44332..44616
                     /locus_tag="ACG84X_000708"
     CDS             44332..44616
                     /locus_tag="ACG84X_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126608.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            44776..45012
                     /locus_tag="ACG84X_000709"
     CDS             44776..45012
                     /locus_tag="ACG84X_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFP9126609.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            45009..45408
                     /locus_tag="ACG84X_000710"
                     /pseudo
     CDS             45009..45408
                     /locus_tag="ACG84X_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
BASE COUNT        14922 a         7887 c         9870 g        12814 t
ORIGIN      
        1 taggactgtg acaagacttt tgtcacagtc cttttttcga attcaacaag taaaactttt
       61 aagaaatatt cagagagtaa aattaaaaat tgctgataaa cgaagatgga aattttatgt
      121 atttttattg gtctatgcaa taaataaatt aaatattcag aatacaattg attttaacga
      181 aagggcttct atcaatggtt gtgttgtatt tatctgccca ggtagagtaa aatagatcat
      241 tatctaaaag gtaattgttc atactatata agtcatttga aagtaaaaag atactgtaaa
      301 taaaaaatgt ggttaaataa ttctcataat cagtgtaagc gttatcaaaa atatagcata
      361 cttgctttgt agatgaatga cacgatatat gtttggtatg ttctgcaaga cagatgaata
      421 tggaggtgga gacaatgtct tccaaagaac taacaatgta tttagagaaa gaattggatc
      481 aactgaaaga aaaggggtta tacaatacga tcgacatact agaaagtgaa aatggtgctt
      541 gtatcatcgt agacggaaaa aagatgatca atctagcatc caacaattat cttggatttg
      601 ccaatcgcga agaattgaaa aaagcatgta ttgaagcaac cgaaacttat ggtgtaggag
      661 caggagcagt ccgaacgatc aatggttcgc tgaaaatcca tcagcaatta gaagaaaaaa
      721 tcgcagaatt caaagggaca gaagcagcaa tcgcctttca atctggattc aactgcaata
      781 tgggcgctat ctctgcagta atgacaaaag aagatgctat cttatcggat gaattaaacc
      841 atgcatctat tattgacggt tgccgcttat ccggagcaaa aatcatccga attaaacatc
      901 aagatatgaa agaccttgag aaaaaagcaa aggaagcgat agaaagtaag aaatataaaa
      961 aaatcatgta tatcacagat ggtgttttct ccatggatgg agacattgca cgattgccgg
     1021 aaattattcc gattgttgaa aaatatggac tgatcaccta cgtcgatgat gcgcacggct
     1081 caggcgtaac tggaaaaggt gcaggaaccg tcaagcattt tggattaagc gacaaaatcg
     1141 atatgcaaat gggcacgtta tcgaaagcta taggtgttgt tgggggttat gtagctggat
     1201 cgaaaacact aatcgactgg ttgaaagcta gaagtcggcc attcctattt tctacttcgc
     1261 taactccagg tgcagctgca gctgcattgg cttcgattac tttgatgcaa gaacatccgg
     1321 aacttgtcga aaaagtttgg gaaaatgcta attattttaa agaagaattg aaaaaagtag
     1381 gctataacat cggtatgtct gaaacaccta ttactccagt cattttggga gacgaaaaag
     1441 tgactcagac tttctctaag aagctgatcg aacatgggat ttatgctaaa ccaatcgttt
     1501 atccaactgt gcctcttggg acaggcagga tcagaaatat gccgactgcg gaacatacga
     1561 gggaaatgct tgatgaagca gtagcagttt atcaaaaaat aggaaaagaa atggaaatta
     1621 tttaactaaa tttagttttt tcgtctattt aaaattagag aacatgttca cgcatatatt
     1681 gttaatcatc tgaagatagt agtaaaaaag atcagggagg atcatcatga aaaaagtatt
     1741 ggtgacagga tgtttaggac aaattggttc agagttgatc acacggctac gtcaagaact
     1801 aggcagtgaa aatgtcattg cgacagatat acgcatgcct gaagtcattg agaaaaacga
     1861 tatctttgag atcctagatg taatggatta cgaaaaaatg cgcagcatag cagaacaata
     1921 tcaagtggac acattgattc atttggctgc tcttttgtca gctgttgcag aagcaaaacc
     1981 acaattagcc tggaatttga acgtgactgg gctggtcaat gcattggaag tcgctagaga
     2041 attccagctg aaatttttta cgccaagttc aatcggcgcg tttggtccaa atactccaaa
     2101 agatcatacc ccacaagata ctcttcagcg tcctacaacc atgtatgggg taacgaaggt
     2161 agctggagaa ctactatgtg attattatta tgtgaaatat ggcgtagata ctcgtggtgt
     2221 ccgtttccct ggattgattt cttatgcaac cttgccagga ggcggtacga cagactacgc
     2281 agtcgatatt tattattcag caatcaaaga aggaaagtac actagtttca ttgatcaagg
     2341 tacatcaatg gatatgatgt atatgccaga tgcgatcgat gccattataa aactcatgaa
     2401 tgcagatcct gatcgattgg ttcatcgaaa tgccttcaat atatcggcga tgtcttttga
     2461 cccggaagag atcaaagcat ctattcaaaa aatcatacca gattttgaaa tggattatga
     2521 tgtggatcct gtacgtcagt caatagcaga atcttggcca aattcactag atgtttcttg
     2581 tgcgcaagag gaatggggct tttcgccgaa atacgactta gatgtgatga caaaggatat
     2641 gttggaaaaa ctgaaagaaa aattggtaga gacggtataa aacaagaacc acatccaaaa
     2701 agttttttat acttttggga ttggctatgg tatgaaaggg gacaagggat ggaagaatat
     2761 caagccacgc cagtaaaaga agtaaaaata gaaaatgaat taaaacgtac gatgggattt
     2821 tttactgctt tatcgactgt tatgggcaca gtgatcggtg caggggtatt ttttaaagcc
     2881 gcaagcgtag cagaagttac aggatccgcc agtttgcata tgttttcttg gtttctcggt
     2941 ggtatgattt ctgtctgtgc aggactaaca ggagctgaac tggcagctgc tattccagaa
     3001 acaggaggga tgattaaata tatcgaacgg atttacggaa atacagcagc ttttttattg
     3061 ggctgggcgc aagtcgtgat ttattttcca gcaaatgtag cagccttgtc gatcattttc
     3121 ggtacacagt tcgtcaatct atttggtctt tcccagtcaa tgattgttcc cgtagctgtt
     3181 acagctgctg tatcgatcct gttgatcaat tttttaggtt ctaaagctgg aggggctttt
     3241 cagtcgatta cgcttgtctg caagcttatt cctttgtttg tgatcgtcat tttcggtttg
     3301 ttccgacaag aaggagtaga cttccaactg tttccgatcc aagcaggaga aaatctttca
     3361 tttttctcag ccttgggagc gggcttgcta gcaacgatgt tcgcatacga cggttggata
     3421 cacgtaggaa atatttcggg agaattgaaa aagccggcga aagatttgcc aaaagcaatt
     3481 tctttaggaa tcatcggaat catgatcgtt tatttattag taaatgcggt gttcttaaga
     3541 accgcatcta tcgacggagt cgcaggaaac agcaatgcgg caagtgacgt tgcaaaaatg
     3601 atttttggcg gcttcggtgg aagactggtc acagttggta tcttgatttc tgtttatgga
     3661 accatcaatg gctataccct tactggaatg cgtctccctt atgttatggc aaaagaaaac
     3721 aacctgcctt ttagcaagct ctttgctaaa cttcatgata aaactaaagt tcctgtagcc
     3781 gcaggtatct tagagctagt catcgctatt ggcatgatga tgatcggtgg ttttgataca
     3841 ctaacggata tgctgatctt tgtcatttgg attttttata cgatggtctt tgttggtgtc
     3901 attcttcttc gtaaaaaaga acctgatttg tttcgaccat acaaagttcc aatgtatccg
     3961 tttattccac tagtagcaat cattggaggg acttttatcg tatcaagcac gcttatcact
     4021 cagacctttt tagcttcgat ggggatagta ttgacacttg ctggtatccc gatttatctc
     4081 tatttaaaac gtagatagct aaaacattcg aattttatta gaactgcact tctctgccaa
     4141 acaaaatatt ttatttaaat gaggagtacg tggaagaaat gtcaaaagta ctcgttaatt
     4201 ttgatcacgt aaatgtcgtt ttgtctacga tgaaatagca aagtaaaaga cagaaatcgg
     4261 gctcaaccga tttctgtctt ttactttgat ttgcgtaact gaactattcg gcgtacgccg
     4321 cgataaatat ttaataaaac caagcaacca gaaatgaaaa tgggaagcca aatcagatag
     4381 acagggtagc caagcacttt agacaaagca tgtggagtca ttttatccat ttcaagaagt
     4441 gcttgctgcc aagtctgaag attgaagact agcatgaaac ccgaaataat caggagaata
     4501 aatcctaaat aatgaattgt agttcttttt cttacataag cgatcgtagc ataaaggaac
     4561 agtaaaaaaa taggtacgcc aaaaacaaag tacatattca gcatctcgac accccctttg
     4621 tgtttatctt actttacttt gaaagaaatg agaaataata gcctcgttac ttgcttgaaa
     4681 cagcaaagga ctgctaagat aagagagata caaagaatca aggaggagtc atatggcaag
     4741 ttatatcgaa ccgattcgtt ttgcgctgat tgtttttcca tttttagcct tagcgatctc
     4801 atctgttttt tttatttatg aatatcgaaa gtatggaaca tttctagtaa caagggcagt
     4861 tattttgtat tctttcgttt tttatttatt gtgtgcgtat tttttggtga tcttaccact
     4921 tccggcaaag gagacggttg cccaaatgac agggccaaag atggagctgc atttatttgc
     4981 ttcatggcaa catttcagag acaacacggt attggtcttg tctgaaccta gtacctacct
     5041 gccggcaatg aagcagagtg tatttttgga accagctttt aatgttttat tactcatacc
     5101 gtttggcatt tatttaagat attatttccg gctttctttt atgaaaacga tgattgctag
     5161 tttctgcctt tctctatttt ttgaattgac gcagctaagt ggactttatt ttatctaccc
     5221 aagaccatac cgcttatttg atgtgaatga tttagtgaca aatacattgg gtggaatcat
     5281 tggttttgtc gttacgccgt tatttacatt tatgcttcct acaagaagac gaatggatga
     5341 actttcttat gaaaaaggaa agactgtctc attgactcga cgcttggtcg cttatttgat
     5401 cgactggaca tttttatctc ttattaattt ggtagcggcg attttcttta aaattgcgtt
     5461 cgattcaggg gcagttactt ctcatatctg gtggctttta ttagaagtag gggtatactt
     5521 tatgattgta ccgtttataa ccaatggatg gacacttggc aaaaaaattg tgcgtatccg
     5581 tttggtggaa gaagaccgcg aacgaatttc tttaaaagca ttgatgatcc gctacgggta
     5641 tctgtacttt cttttttatg gtttaagctg gttggggcag ttgcttcagc aaatcatgaa
     5701 ttcgacaacg aatacggtgt tgcagatgag tgcagtattc atttctctcg gtgtcttgtt
     5761 actacaaggt atttttattt taaatatctt gctatcattt ttgagaaaaa aacggattct
     5821 gttttatgaa aaagctagtc acacatatac tgttagcacg attggccaaa caaaggatga
     5881 tgattctcga aattagctga gcaaaaacgc tttgtctgtg ttataatgcc aaagtcgtga
     5941 taatttaaag agaagaggtg cacgaatgaa taattttgat atattccgct tcaaaccgtt
     6001 tatcaatgaa gcgttaaccg caaagggctt caaacagccc acagaggtcc aggaacgttt
     6061 gattccttta attgcaaaag gaaaaaatat cattgggcaa tctcaaactg gtacaggaaa
     6121 aacacatacg tttttgttgc ctttgtttga aaaaatcaat gcagaaaaag aggaagtaca
     6181 agttgttatt acagctccaa gtagggaact agctgcacag atctatgaag cagctacaca
     6241 aatcgctaaa ttttctacac cggagatccg tgtctcgaat tttgtcggcg gtacagacaa
     6301 acagcgtcaa ttaaatcgtc tgcatcacca acagccacag gttgtagtag gcacgcctgg
     6361 tagaatatta gacatgatga atgaacaagc gctgaagatt cacaccgcat ttgcatttgt
     6421 tgtcgatgaa gcggatatga cattggatat gggtttttta aatgaagtag accaaattgc
     6481 aagtcgatta ccagaaaagc tgcagttttt agttttttct gccactattc cagaaaaact
     6541 tcgtccattc ttacgaaaat acatggaaaa tccaatcatt gaagaaatca aaccaaaagc
     6601 agttatttct gaagacattg aaaattggct gatttcaaca aaaggtaaag atgagaatca
     6661 aatgatttat caactgctga caattggtca tccttattta gcaatcgtat ttgccaatac
     6721 aaaacagcat gtggatgaaa ttgccgatta cttgaaaaac caaggcttga aagtagcaaa
     6781 gattcatgga gacatcaccc caagagagag aaaacgagtg atgcgacaag tacagaatct
     6841 ggagtatcaa tatgttgtag cgactgattt agctgctaga gggatcgata tcgaaggtgt
     6901 ctctcatgtt attaatgcag aaattccaga agatctagac ttctttatcc atcgtgtcgg
     6961 acgtactgga cgtaatggct taaaaggaac ggccattacg ttatattcgc caaatgatga
     7021 gcaagccatt gatgcgatag aaaaattggg cgtctcattt gaaccaaaag aaatcaaaaa
     7081 cggggaaatc gtcaaaacat acgatcgtaa tagacgtgcc aaacgagaaa aatcaaaaga
     7141 tgtattagat cccacgctga ttggtcttgt gaagaagaaa aagaaaaaga tcaagcctgg
     7201 ttataagaaa aaaatcgatt gggcaattgc agaaaaaaat aaaaaagaac gcaaaatcga
     7261 acgcagacag caaagccgta ctgctcgtaa aaataagaaa aattcacata aataaaaaac
     7321 aagaggttgt gacaaaaggc gtgtcacaat ctcttgtttt taagctagac tttttttcat
     7381 tccgatacaa agtacttcat cttcaataaa aggttctgtg caagtatgat acccttgttt
     7441 ttcataaaaa tctacagccg tcatttcagc tactacataa ctagtctgac aaccttctga
     7501 aaccgcccgt ttttcagcag cttcaagcaa ctgaccgcct aacccttttc ctcggtattc
     7561 ttttgctacg caaaatcgtt ccggcttgaa gcaagtaggt gttttctttt cataacgcaa
     7621 agtagctact ggtctttttt gatcaagaaa tagataatag gtttgttgcg ggatatcttt
     7681 tccgtcgaat tctagttctg caggaatccc ttgttctaat acaaaaactt gatatctcaa
     7741 aaagcagcta gctgcgcgta tccattcatc cgctccaact atttttttca tcatattcct
     7801 ccttgtcatg aatagcagag atgtattgat tcctttattc ttatcgtacc aaaaatcgtg
     7861 gagtatgacc aaaaggaaat gaaaataaaa attgagatat tgacagtgat caatagaatg
     7921 cgtatactaa ttaagtacga aaaggatatg atttgttttt taagactcac agaaaattct
     7981 ttcttggctg aaaaaagaat agtcactaat caaattgctc cctttttcta ttttggtaga
     8041 aataccgacg cagctcagcg ttatcgagtt taagaggtaa tgattacaca tcattgcaat
     8101 caaggtggta ccgcgagttt tcgtccttgg ctgtgatggt gtttttttgt atttaattta
     8161 tagaaagcag gtaatgacat gaaacaatta agtagtgcac aagttcgaca aatgtttctt
     8221 gatttcttcc aatctaaagg acatacgatt gaacctagtg cgtctttgat ccccgtgaac
     8281 gatccaacct tattgtggat caactctggt gttgcaacat tgaaaaaata ttttgatggt
     8341 tcagttgtgc cagaaaatcc aagaatcaca aatgcccaaa aatctattcg aacaaatgat
     8401 atcgaaaatg tcggtaaaac agcacggcac catacgatgt ttgagatgct gggtaatttt
     8461 tcgattggtg actatttcaa aaatgaagcc atccactggg catgggaatt tttgactgat
     8521 ccaaaatgga tggcattcga tccagaaaaa ctttatgtaa cagtttatcc aaaagataca
     8581 gaagcaaaac gcatctggca tgaagaagtt ggcctgccac tagatcacat tattgatgta
     8641 gaagacaact tctgggatat cggtgcaggc ccatgtggtc cggatacgga aattttctat
     8701 gaccgtggag aagcttataa cgatttagca gaagacgatc ctgaaaacta tccaggagga
     8761 gaaaatgaac gttatttaga aatctggaac ttagtatttt cagaattcaa ccataagcct
     8821 gataacacat ttgaaccact tcctcataaa aacattgata cggggatggg attggaacgc
     8881 atggtctcaa tcgttcaaga tgcgtcaacg aactttgaga cagacttgtt tatgcctatt
     8941 atccacgccg tagaaaagct aagcaaacaa gtaaaatatg gtgaaaaccc agtaacagat
     9001 atttcttaca aagtaatcgc agatcatatt cgcgcccttt catttgctat tggcgacggt
     9061 gcattgccat cgaatgaagg gagagggtat gtcttacgcc gtttgcttcg tcgtgctgtc
     9121 atgcatggga aaaaattagg tattgaacaa gcattcttat atcgtttagt ccctgttgtt
     9181 ggggaaatca tggtaagtta ttatcctgaa gtacttcaac aaaaagaatt tattgaaaaa
     9241 gttatccgta cagaagaaga acgtttcaat gaaacaatca atgaaggttt ggaaatctta
     9301 aatcaagtga tccaagaagt aaaaaacgaa aacgggacga ctctagcagg aaaagacatc
     9361 ttcaaactat acgacacata tggcttcccg gtagaattaa cggaagaggt ggcagaagat
     9421 gaaggactga aagttgatca tgctggtttt gaaaaagaaa tggatgcaca acgcgaacgt
     9481 gctcgctctg cccgcagtac tgaaaaatca atgggggtac aatctgcttt attgacagat
     9541 atcaaagtag aaagtaaatt cattggatac acagaacaag aatcagatag tcaattattg
     9601 gtcatcgtta aaggtgagtc tcttttgaat gaagtcgcag aaggtgaagc tcaaatgatc
     9661 tttgatcaaa cacctttcta tgcagaaatg ggtgggcaag tagcggatca aggatggatc
     9721 atgaatgaag taggcgaaat cgtagcagtt gttacagatg ttcaaaaagc gcctaatggt
     9781 caatttatgc acaccgtaga agtaaaagca ccaatgagtg aaggacaaac ctatcatcta
     9841 ttgatcgatc aatcgatgcg caatcggatc atcaaaaacc atacagcaac ccatctactg
     9901 cacaaggcat tgaaagaagt acttggcgag catgcaaatc aagctggttc tttagtcgct
     9961 cctggacatt tacgattcga ctttacccac tttggtcaaa tcacttcaga tgaattagct
    10021 gaaatggaaa gaatcgtcaa cgaaaaaatc tgggaagcta tcccagttga aacaattgaa
    10081 acagatatcg atacagccaa aaacatgggt gcaatggctt tgtttggtga aaaatacgga
    10141 catgacgttc gagtagtaaa tattggcggc tggtcaatcg aactgtgcgg aggcacacat
    10201 gtagcaaata cagaaaacat cggaatcttc aaaatcgttt ctgaatcagg aattggtgca
    10261 ggcgtgcgac gaatcgaggc tgtaacaagt aaagaagcgt acgaactact tgaagaagaa
    10321 gaaaaacaac taaaacaagt agcaacaatt gttaaatcac ctcaattgaa agaagttgtt
    10381 tcaaaagcgg aacaattgca acagcaagta agagagctac aaaaggaaaa tgaacaatta
    10441 gctagcaagt tagcgaatca acaagctggt gatgtattca aagatccaga aacgatcaat
    10501 ggaaaaacaa tcattgcagc acaagtaaaa gtgaaagata tgaatcagct gcgtcaatta
    10561 gctgaccaat ggaaacaaaa aaatatttca gatattcttg ttttagcaaa cgaacaagaa
    10621 ggaaaagtca gtctgctagc ggcaatgacg aaagaatcaa atgaagctgg actaaaagct
    10681 ggcgacttga ttaaagcaat cgcaccgaaa gtaggcggtg gcggtggtgg acgtccagac
    10741 atggcacaag ctggcgggaa aaatcctgct ggtattccag atgcacttaa agctgcgaaa
    10801 gaatgggttg cgcaacaata gggcgtttac gtttgacaga aaaacaaaag ttcaaacatt
    10861 gaacgaaaca tgattatggg ggcgaagaca aacaagtctt gccctcatac ttttttcaat
    10921 tggatggcgc atctaatcaa atggtcggat tcggatggtc tttagttgac gaaagtgaca
    10981 gaaattttta cgattagtat aaataaaaag gggtgaaaaa atgaatagta gaaataagac
    11041 ctttcgacta gtcttacgtg cgatcttgtt agcaatcatc atcgtacaag cgatggttcc
    11101 ttggctgggg tttattccat taggattcat tagtttaaca attatccata tcacagtaat
    11161 tattgctgca gtagtattag gcccaaaaga tggcatggtg attggcttgt tttggggaat
    11221 cgctacaatt gttcgtgcct atgccatgcc aacaacgcca tttgatacat tagtgttcac
    11281 gaatccgatt atctcggtag ttcccagagt acttgttggc ttagtagcag gcttggtttt
    11341 ccactggatt tatcaaaaaa ataaatcaat aacgatcagc tcagcctttg caggggtact
    11401 gggttcattg gtcaatacag tcttagtgtt aggattcatg ggattatttt atacaggtgc
    11461 aacggcagat gcctatggtg tagactctgc tcttttattt aaaaccttag caggggttgc
    11521 agcaatcaat gggataccag aagcaatagg tgcgggaatc ataacaccat tactagcaaa
    11581 agcgttattt gcagcaacac cgttgaaacc agaataatga ccatctttta atagtaatag
    11641 gacgcacgat agatagaaaa aggaagagag gagaggaaaa caatcgtcct ctccatcttt
    11701 ttacctgagc aacaagcaaa ctagaagggg taaaaaactt ggctaagaaa caagaagaaa
    11761 aaaagaaaca aataccgcaa cagcggacaa aaaaaggagt actagcgggt atcttaggat
    11821 tggttacgaa tctgatcttg tttgtctcta agctaatgat cgggcttttt tcaggaagtg
    11881 tctccattat ggctgatgca gtgaacagtc tatcagatac tgcttcatcc atattgactt
    11941 tgatcggatt taaaattgct gcaaagccag cagatcagga acatccttat ggacacgaac
    12001 gcttcgaata tatcagtggg ttatttgttt cgatcatcat tacttatgta ggatttcaat
    12061 ttttagagtc ttctgctgaa aaaatcatcc atccagaaaa tgtctcttta acacccatcg
    12121 tcttttttgt cctaatcatt tccatctttt tgaaatttgc acaaggcaaa atgtatcagg
    12181 ttattgcgca atccattgat tctgaaacat tgagagctac agcaacagat agttataatg
    12241 atgtctttac tacactggct gtattgcttt cagcagcaat cgaatgggta actggatggc
    12301 gtattgatgg atatataggt tttgctttag cattatatat cctttatagt ggattgacga
    12361 tgcttcgaaa ttttgtatac gaactattag gaagtcgccc aacgccagca gagattgaag
    12421 aaatggaaga gcatttaaat gcttgcgatg atatacttgg ctatcatgat ttattggtgc
    12481 ataactatgg acccaataaa cgctttgcat cagtccacat cgaagtagat gaatcaatga
    12541 atttgaatgt ggctcataag attattgatc tgatagaaaa agactttaaa aagtctttgg
    12601 atgtggaact tgtctgtcac ttggatccaa tgcctgttga taacgaaaaa tactataata
    12661 tcttgcggca gttaaagcaa attcttcttg aaacaggtac agggcttaat attcatgatt
    12721 ttagagtaat tcatcaagga aaaacgctgc aatttgatgt agtggtccct gagaaattcc
    12781 agtttgttga tacagaacta gaaagaatct tacgtagtca aatagaagaa aaaatcggag
    12841 attaccaatt ggaaattacg tttgatcaca attatctttt atattaaatg agaaactata
    12901 aaaagactcc ttaaagtttt taatttaaag agtctttttt tcttttaatt gtttatggag
    12961 agcctgacgt gcaagattat ctgctccttt atttttgttt tcgggcaacc attgcaggat
    13021 caataaagaa aattcggata gaagttcttg gattctttga aggtagggaa ggaagagctc
    13081 gttcttcgtt gcgtttttgt cgaccgtaga aactagtgtt ttgctgtctg aaaaacagaa
    13141 aatcgtttca ttctgtaagt cgtttttctt tagaaattct aaagttttta aaaagacttc
    13201 gaactctgct tgatggtttg tccctataga aagcgggata gatagctgtt cttgtttacc
    13261 ttgatagaca atcaagattc cacctccact aggaccaggg ttgccttttg tagaggcatc
    13321 aatgtatact tttaacataa aaagagattc tcctttttgt tcaaactaat gttatggtaa
    13381 gattatatca ttactgaatc ggtgagaggt tagagaatga aaaaaaatat tcgatggcag
    13441 cctgaactgg cacatacgat catctattgg tcattgacct tgatcattct gttttttagt
    13501 ctgattcttt ctttagaaaa cacaggtcct tattggaaaa gcaattttgt tttaggtatt
    13561 tttcttgttt ttctatttct aggtttgcgg cgttctttta ttttaaaatc aaactctgtg
    13621 attatacgtt atgctgcttt ttggaaagac cgagaaatat ctgtcggaca gattcgatct
    13681 ttgacgccaa ctaatactgg ggtgcaaatg atgttgcaag atgagaaagc cccatctgtt
    13741 ttcatgatgc gaaaaaaaga tcaagtagtc ctttttgatc attttgaaaa aaacggaccc
    13801 aaatcagaat caattcctta tccttatacg aaaaaaagaa aaagctaatt ttaaaaatca
    13861 gaacctaaaa aaacgaattt ttacaggaaa agaaaagagt gagacgtacg gttcatcccg
    13921 tttagcgtct cactctattt gtttatctat tcatgcatac tagtatcggt agtctgaacg
    13981 ttgcctttct tgacatgggc agcttgtgtt cctcgattcc cttcgatgat ctcaaattcg
    14041 accacttgat tttcttccaa agttttgaat ccctcttctt caatcgcagt aaaatgtaca
    14101 aaaatttctt ctgtgtcatc ataactgata aagccgtatc cttttttgtt gtcaaaccat
    14161 tttacaattc ctgtggtcaa agcactcacg acctttctaa agtctgatca tagccttcat
    14221 tataaagagt atttataagt acgtcaaata aattaaaaac ctgtaatttt atgttttttt
    14281 tctgaataaa aaaaggtata attggcatat cttaacaaag aagatatttt gttgaataaa
    14341 gttcgtgaaa aggggtaatc aaatgaagaa tgatctgcaa atttcacaag aaacagagct
    14401 agaaccgatt gttgaagtgg ctagtaaatt agatcttaag gaagacgatt tggaactgta
    14461 tgggaaatat aaggcgaaaa tcaatttttc tggaatcaat cgatcaaagg ataacgctga
    14521 ggggcatttg atcttagtta cttccatcaa tccaacacca gctggcgaag gaaagtcaac
    14581 gatcactgta gggttaggag acgcgctcaa taaaatcaat aaaaaatctg ttattgcatt
    14641 gcgagaaccc tcacttggtc ctgtgatggg aatcaaaggt ggtgctgcag gcggaggata
    14701 tgcacaggta ttgcctatgg aagatatcaa cttgcatttt actggtgaca tgcatgctat
    14761 cacaacagct aataatgcat tatctgctct tttagataat catattcatc aaggaaatga
    14821 attgaacatc gatgcccgcc gagtgatttg gaaacgggta gtcgatctca atgatcgtga
    14881 actgcgtaaa gtaattgttg gcttgggtgg gccaatccaa ggtgttccaa gagaagatgg
    14941 gtttgatatc acagttgcca gcgaaatcat ggctatcttg tgtcttgcgg cagaccttga
    15001 agatttaaag gctcgtcttg caaggatcgt tgtcggctat acatttgacc gtcagcctgt
    15061 gactgctgga gacttgaaag cagaaggcgc tctggcatta ctgctgaaag atgcaatcaa
    15121 gccgaatctt gtacaaacaa tttacggaac accagctttt gtccacgggg gaccgtttgc
    15181 caatatcgct catggctgca atagtatttt agctaccaag acagcattga gattagcaga
    15241 ttacgttgtc acagaggcag gatttggtgc agatcttggc ggagagaaat ttttagatat
    15301 caaagtacct aacttgaaaa aagcgccgga tgctgtggtg attgtcgcca ctgtccgtgc
    15361 attgaaaatg catggcggaa tgaaaaaaga tgaacttaaa aatgagaatc ttgatgcttt
    15421 gaaagtaggt tttgcaaatt taaagcgcca tatacgtaat atggaacaat atcagctacc
    15481 tgtgatcgtc gcaatcaatg aattcgtaac agatacagac aatgaactca cactgttgga
    15541 gcacttgtgt gaaaatcagg ggattcttgc caagagagcg agtgtatggg cagatggagc
    15601 agaaggcggc gttgatttag caaaagctgt agtacgattg attgatagaa aagaagctaa
    15661 ttacaagcca ttataccgcc tagaagaaac gatacaagaa aagacagaaa caatcgtcaa
    15721 gaaaatttac ggaggaaatg gtgttgtttt cagcaaaaaa gcgcaaaaac aaatagaaga
    15781 gtttacgaag aatggatggg acaaactgcc gatttgtatg gcaaaaacac agtattcatt
    15841 ttctgatgat ccttcactgc taggtgcacc ggaagatttc accatcacga tccgcgaaat
    15901 catcccaaaa ttaggggcag gatttttagt agccttgact ggagatgtta tgacgatgcc
    15961 tggtttgcct aaaaaacctg ctgcattgaa tatggacgtg acaaatgacg gagaagtgtt
    16021 gggattgttt taagcttgat tataatctac catcgaagga gctgtatttt gactacagct
    16081 tcttttttta gacgataggg aattaatttt gtttacacta ggatcattct ttttctttat
    16141 tgtattttga gctatactaa agcataatag gagggtatga tgaaaacgac atttataaga
    16201 aaaaccggtt tttacggtat gggtagctcg attcagctaa gaatcaacaa tgaaaaacgc
    16261 agtgttctca gtcatgaaca aaagataacg cttgatctgg aagtgccctt tacgatgcag
    16321 gtcacctttt attggctaaa aagccccgtt tatacagtga aagaagcaaa gcctgcttat
    16381 gtgatcacaa tgaattactt gattcttcaa atctatccgt ttttatttct agcaactggg
    16441 ttgggggccg ttttcctaca aaatttattt ttcagttttt ttgcagttat tgtgttgatt
    16501 gcgttctttt tctatataaa aaaccgggca tatttgatca aggaggaaaa ttatggcaaa
    16561 ctctgatctt tttttaatca gtttcaatcg aatcgaaaaa tggatgagag acgagatggg
    16621 aaatgcacga aatatgggat ttaccgaact tgtcagacgc ctagctcaaa gaaaacaatt
    16681 aatgatcaga aaatacgaag atgatctttt acagcttgct cagttaagga atgcgatcgt
    16741 ccatgatcgg atcgcagtcg attttgtcat tgcagagcca aatgattgga cagtcaagcg
    16801 aatccagctg atcgaacaag aactgattca gcctgaaacc gtgctgcctc gatttgcaaa
    16861 acgtgtaaca ggttttgaac aagatcttcc gttacttgaa ctgttaaaga tagtagcaga
    16921 aaaaaggtat tcacaatttc cgttatacaa taaaggaaaa tttgtagcat tgattacttt
    16981 acgtaatatc gggttttggc tagcaaaaga aagccaaaaa ggtccggttg atttaacaaa
    17041 taaacgagcg ttggatttga tcatccaaaa cggaaagtac acaaattatc attttgttcc
    17101 agctaaaaca catatttacg aggttgaagc gatgtttcgt gagcaaggga ctttggaagc
    17161 cgtacttatc actaaagatg ggaatcccga tggtaatctg ctcgggatcg tacgacctcg
    17221 tgatatttat aaacaaatag aaaaggattg attttttgtt aattatttat tggatattca
    17281 gcgctttgct agtaggagtg gatcagttgg tcaaatggtg gatcactgat aatctagcgc
    17341 ttggagagac gaaaaatctt ataccaggta ttttgtcact gaatcatatt cgaaacactg
    17401 gagccgcatg gagtatgcta gaagggaaga tgtggttctt tactatagtg acactcattg
    17461 cagtcgttgt gattctcaca ttgatgatta aaaatcgtga aaaaggtaat cgctggttca
    17521 tgattggatt gagtttgatt ctagctggtg cgattggcaa ttttatcgac cgtattcgtc
    17581 ttggctatgt agtagatatg ttccagacag attttatgag ctttccgatt tttaacgtag
    17641 cagatgtgac acttgtatgt ggagtgattt gtatgttaat ttatattatt ttagatgaaa
    17701 aggatcaaag aaaaaaatga cagaacttaa aacgacgatt caccatgaat ctggtaggat
    17761 cgataaagta ttgactaatt tattcaccga ttacagtcgt tcgcaaattc agctgtggct
    17821 gaaaaatgga gcggtttctg tcaatggaca gccagtcaaa gcaaattaca aagtaaaaca
    17881 aggagacgag attactgtct tgatccccga accagaaaca ttagatgtgg tcccagaaaa
    17941 tatcccgttg acgatcgttt acgaagatga agatgtagcg gtgataaaca aacctcaagg
    18001 aatggtcgtt catccttcag caggtcatac gcatggcaca atggtcaatg cgctgatgta
    18061 ccatatcaag gatctttcta cgatcaacgg cgttattcgt ccaggtattg ttcaccgaat
    18121 cgacaaagat acttccggac tgctaatggt tgccaaaaat gaccaggcac acgaatcatt
    18181 agctcagcaa ttaaaagata agacctcttt gcgcaaatat gttgctttag tccatggaga
    18241 gattcctcac gaaaaaggaa ccatcaatgc gccaatcggc cgttcgaagg aaaaccggaa
    18301 aatgcaggcg ataagagaag atgggaagtc ggctgtcaca cattttactg tattggaacg
    18361 tttcgaagga tttactctgg ttgaattaaa actagaaacc ggaagaacac accagatccg
    18421 tgtgcatatg aagtatatcg gttatccgtt agctggagat ccagtatacg gaccgaagaa
    18481 aactttgaaa ggcaatggtc agtttctcca tgcgcaaatg ttaggtttta cgcacccgac
    18541 tacaaacgaa aagatgatct ttgaagcacc tcttccagaa gtttttgaaa aaactttaga
    18601 aaaattaaga aaaaacattg cattttaatt tagataacgg tatagtaatt aacaacgaaa
    18661 gcataaaact taatagaatt cctttaagtt tagtcccgtg aggctaagaa gggtgggagc
    18721 aaggatacgt atggtgcgcc ataagtagat tgctcattga catagtatag ctatcagtgt
    18781 atcagtataa gctcagtcta aacattcctc ctgtcctctt agggcaggag tttttttatg
    18841 caaaaaagta gggggaatga aaatgcaagc aaaagaagta gtagatcagg taaccatgaa
    18901 gcgagcattg actcgaatta cttatgagat tatcgagaga aaccatagta tccaagatat
    18961 cgtattggta ggtatcaaaa cacgaggaat ctacattgca tcaagaattg ccgaacgcct
    19021 gaagcagcta gaagatatcg atattcctgt aggagaactg gatatcactt tataccgaga
    19081 tgacaaaaaa gaaaatccag aagaaccgga acttcattct tctgacatcc cagtttcctt
    19141 agaaggaaaa gaagttattt tgattgatga tgttttgtat acaggacgaa cgattcgagc
    19201 agcaatggac gcagtaatgg attttggcag accaagaaaa atttcattag cagtcctggt
    19261 cgatcgtggg catcgagaat tgccaatccg tgcagattat gttgggaaga acattccaac
    19321 atctcgggcg gaagagattt tagtagagat gcaagagctt gatggacaag atcgcatcat
    19381 gattttgaaa gaggaagatt agaggagaga gaaacatgtc ggagaaaaaa ggatttcata
    19441 atgatgacgt ggtgttagat atccacgatc gcccaacccc aggacattgg gtaggattaa
    19501 gtttacaaca cttgttcacg atgttcggag caaccgtgtt agtccccatc ttagtaggta
    19561 tcgatccagg tattgcgcta gtcagttcag gactaggtac attggtgtac ttatttacta
    19621 ctaaaggaaa gatacctgcg tacttaggaa gcagcttcgc tttcattgca gcgatgcagc
    19681 ttttgatgaa aacagatggt tatccagcga ttgcacaagg agcagtcaca actggattag
    19741 tctatttgat tgttgcgctg atcatcaaaa agatcggttc agcatggctg gataaaatct
    19801 tgcctccaat cgtcgtcggt ccagtcatca tggttatcgg gttgggactt gcggcaaatg
    19861 cagcaacaaa tgctatgtat aatcagggca cgtatgattt caagtatatt gctgtagcgc
    19921 tgatcacatt aggattaaca attttcttca acatgtggct aagaggtttt ctcggattga
    19981 ttccgatttt actaggtatt attagcggat acatcgtagc cttgctgttt ggaatcgtgg
    20041 atactaagcc aatcgtagac gctgcctggt ttgctgttcc taactttgag attccctttg
    20101 tacaatatga accaaagcta tatcttggag caatcacaac aatggcaccc atcgcttttg
    20161 tgacgatgac agagcatatc ggccatctta tggtattgaa taaactaact aaacgtaatt
    20221 tctttgaaga accgggtctt cataagacgt tgacaggtga tggattagca caaatcgtgg
    20281 cagcctttgt cggaggtcct cctgtaacaa gttacggtga aaacattggt gttctggcta
    20341 tcacacgtgt ccatagcgtg tttgtgatcg gtggagctgc agtatttgca gtcattttag
    20401 gattcgtagg aaaattaagc gctttgattt taagtatccc tggaccagtc atctcaggaa
    20461 tcagttttat cttatttgga gtaattgccg caagtggaat gaagatttta atcgagaaca
    20521 aaatcgattt tgataaaaag aaaaatctgt tgattgcttc agttatctta gtagtaggaa
    20581 ttggcggact cgtctttgaa gtaggcacat ttacattgtc ggcaatggca ttagcaactg
    20641 tacttggcat cattttaaat cttatcttac cagaaacttc acgaagcgaa gaaaactaag
    20701 gaggaaacat tatgatcatc aaatcagaac gtatcagctt aaagcattta ttgaccgttg
    20761 aggcacttac tgatcaagaa gttatgggct tgatccgcag agggcaggaa ttcaagcaag
    20821 gtgctaattg gactccgcaa aagcgccagt actttgctac aaacctcttt ttcgaaaata
    20881 gtactcgcac acataaaagc ttcgatgtag cggagaaaaa actagggcta gaagtgattg
    20941 aatttgaagc aagcacaagc tctgtccaaa aaggggaaac actatacgat acagtactga
    21001 cgatgtcagc attaggcgta gacgtagcgg ttatccgtca tggtgatgag aactattatg
    21061 acgaactgat acaaagtaaa acaatccagt gttcgattat caatggagga gacggaagcg
    21121 gacagcatcc aacccaatgc ttgcttgatt tgatgaccat ttatgaagaa tttggtcatt
    21181 ttgaaggtct gaaagttgcc atcgtaggtg atatcactca ctctcgcgta gctaaatcca
    21241 atatgcagat gttaaaacgt ctaggcgcac aagtattctt ctcaggtcct agagaatggt
    21301 acgacgatga attcgaagtg tacggacatt atatgccatt ggatgaacta ctagatcaag
    21361 ttgatgtcat gatgatgctt cgggtgcaac acgaacgcca tgatggaaaa gaaagtttct
    21421 caaaagaagg ctaccatcag gaacatgggt taacagttga gcgtgcgaag aagttgcaaa
    21481 aacatgcaat cattatgcac ccagcaccag ttaaccgtga tgtagaatta gctgattcat
    21541 tagtggaagg attacagtcg cggatcgttc agcaaatgag caatggagta ttcgtcagaa
    21601 tggcaatctt agaagcagtg ctaaatggaa aagcgtaatt ataggaggat gaaaaaatga
    21661 aaacactcat taaaaacggt cagatcaata cacgaaaaaa tatgacgaca ccagcagaaa
    21721 tttggataga agatgggcga atcaaagcaa tcggtacagg attctcagaa gccgaatttg
    21781 atgaagtgtt tgatgcaaag ggacaattga tcacacctgg tttagtggac gtccatgttc
    21841 atttgagaga gccaggattt acatacaagg agacgatcga agctgggact cgctcagctg
    21901 ctcgtggcgg tttcactact gtatgcgcga tgccgaattt aaatcctgta cctgatacgg
    21961 cagaaaagct gagacaagta tatgacatca ttagaaaaga tgcagttgtg aaggtattgc
    22021 agtatgcgcc aatcacagaa aatctgcgaa gtgagaaatt agttgatcaa gaagcactga
    22081 ttgaagaagg tgcttttgct ttcacaaatg acggtgtagg tgtccaaaca gctgggacga
    22141 tgtatctggc tatgaaagaa gctgcaaaaa acaataaagc cctagtagcc catacagaag
    22201 atgaatcttt attatttggc ggcgttatgc acgctggcaa gaaggcagaa gaacttggtc
    22261 ttcccgggat cttaagcgta accgagtctt ctcaaattgc tagagatctg ttgctagctg
    22321 aagcaactgg tgttcattac catgtttgcc atgtttctac taaagaaagt gtccgtgtaa
    22381 tcagagacgc aaaaaaagca ggaatccacg taacagcaga agtttcaccc catcatctta
    22441 ttttgatcga cgaagatatt cccgaagatt tcggcttttg gaaaatgaac ccgccgctaa
    22501 gaggacggga ggacagagaa gctttgatcg aaggcttgct tgacggtacg atcgattgca
    22561 tcgctacaga ccatgccccc catggattag aagaaaaaag ccaaagtttc atgaaatcac
    22621 catttggtat cgtaggaagc gaaacagcgt ttcaactgat ctatactcat tttgtagaaa
    22681 ctggtcgatt cacgttggaa caagtgatca attggttggc agttaaaccg gctgagattt
    22741 ttggtttgaa tgcaggaacg ctaacggttg gtgcccccgc tgatgtagca gtttttgata
    22801 ttacacaaac ttgcacgatc gataaagaag actttttatc aaaaggggag aatacacctt
    22861 ttatcggctg gaaagtaaaa ggcgaaacac aaatgacttt tgtcaacgga aaacttgtgt
    22921 ggcagaaggg agaataaaag tatggaacgt ttgcttatat tagaagatgg aacagttttc
    22981 gaaggaaagg cttttggtgc agatgctagt gtcttcggag aaatcgtttt tacaacaagt
    23041 atgactggtt atcaagaaac tatcactgat caaagtttta acggtcaaat cattacattt
    23101 acctatccta tggtgggtaa ttatggggta aatagagatg attatgaatc gatttctcca
    23161 acatgcaaag gagtagtagt aaaagaacat gcacgtgtag cttcaaactg gcgaaaccaa
    23221 atgacgctag attcattttt gaaacaaaaa ggaattcctg gaatatcagg tatcgatacg
    23281 cgcgccctta ctcgcaaaat ccgtgaagtc ggaacgatga aagctagtat agttgatgct
    23341 ggagattcct tcgaacatgc atttgatcag ctgaaagcaa ccgttctagc aaccaatcaa
    23401 gtgcagcaag tctcaactaa caaaccttat ccaagtccag gaacaggtcg gaaagtcatt
    23461 gtcattgact tcggcttgaa acatagtatt ttacgagaat tgagtaaaag aaactgtaac
    23521 ctcacagtac ttccctataa cacagatgcc gagacgattt tagcgctatc accagacgga
    23581 gtcatgctga cgaatggacc tggtgatcca aaagatgtgc cagaagcaat cgaaatgatc
    23641 aaaaaaatcc aaggaaaagt accgattttt ggtatttgtc tcggtcacca gttatttgct
    23701 ttagccaacg gtgcagatac ctataaaatg aaattcggac atcgaggatt aaatcacccg
    23761 gtacgagaag tagcgaccgg aagaattgat tttacttctc aaaatcatgg ctatgcagtc
    23821 gatgaagcca cgattgatcc agaaaaactc atcgtaactc atgtagaagt aaatgacgga
    23881 acagtagaag gagtcaaaca cagagattat cccgctttca gtgtgcagtt tcatccagat
    23941 gctgcccctg gtccgcatga tgcactacat ttatttgatg aatttatgga aatgatggac
    24001 gcaggaaagg agcagtaaac agatgccgaa acgtacagat atcaagaaaa ttatggtgat
    24061 tggatctggt ccgatcatca ttggtcaagc cgcagaattt gactacgcag gaacacaagc
    24121 ctgccttgcc ttaaaagaag aaggatatga agtggtttta gtaaattcta atcctgcgac
    24181 gatcatgacg gataaagaag tggcagatca agtatatatc gaaccgatca cacttgaatt
    24241 tgtatcaagg attcttcgaa aagagcgtcc agatgctctc cttccaactt taggcggaca
    24301 gacaggcctc aatatggcaa tggagctggc agcatcaggt attttagaag aattgaacat
    24361 agaacttcta ggaacaaagc tttctgcgat cgatcaagca gaagatcgtg atctattcaa
    24421 acagttgatg aaagaattga atcagccaat ccccgagtct gaaatcgtca atacagtaga
    24481 agaagctgta gattttgcaa ataaaatcgg ctatcctgtc atcgttcgtc cagcctttac
    24541 tttaggcgga actggtggag gtatgtgtga aaatgaagaa gaattacgta tcgtatcaga
    24601 aaatggatta agtctttccc ccgctaccca atgtttgatt gaacgaagta ttgcaggttt
    24661 taaagaaatt gaatatgaag tgatgagaga ttcggctgat aatgcaatcg ttgtctgcaa
    24721 tatggaaaat tttgacccgg tgggtatcca tacaggtgat tctatcgtat ttgcccctag
    24781 tcaaacattg tctgaccatg aatatcaaat gcttcgtgat gcttctcttt cgattattcg
    24841 agcacttaag atcgagggag gctgtaatgt ccaactcgct cttgatccac atagttttaa
    24901 ttattatgtg attgaagtca atccgcgtgt ttctcgttca tctgcgttag caagtaaggc
    24961 gactggctat ccgatcgcta agctagctgc taaaatagcg cttggattaa cattagacga
    25021 aatgaaaaat cctgttacag gaacgacttt tgcagaattt gaacctgcat tagattatgt
    25081 tgtagctaaa attcctcgct ggccgtttga taagtttgaa aacggagaac ggcttttagg
    25141 cacgcagatg aaagcaactg gtgaagtgat ggctatcggt cggaatatcg aagagtcttt
    25201 attgaaagct gtgcgttctt tagaaatcgg tacacaccat atcgaacttc ctgagttggc
    25261 agacatcacg gacgatgacc taatccaaaa agtggttcga gcacaagatg atcgcctgtt
    25321 ttatgtagct gaagctatta gaagagggta caccatagaa gaattagcgg atttgacaaa
    25381 aatcgattta ttctttttag ataaactgtt gcatatcgta gaaatcgaac agcagttgaa
    25441 acagcagccg ttggatgaca agatattgaa aacagcgaaa caaaacggtt ttacagacaa
    25501 aaaagtggcg gagctgtggg aaataaacga agaagccgtt cgccagatga gaaaagaaaa
    25561 tgatttgatt cctgtatata agatggttga cacttgtgca gcggaattcg aatcaaaaac
    25621 accttatttt tatagttcct atgaatatga aaatgaaagt tcacgatcag aaaagccctc
    25681 aattctagta ctgggatctg gtcctatccg tatcggacaa ggggttgaat ttgactatgc
    25741 gactgtgcat tctgtcaaag caatccagca ggcaggatac gaagcaatca tcatgaacag
    25801 caatcctgaa acagtttcga ctgacttttc tatttcggat aaattatatt ttgagccatt
    25861 gaccttcgaa gatgtgatga atgtgatcga gctagaacag ccgataggag taatcgttca
    25921 atttggtggt cagacagcaa tcaacttagc cgaacctttg actgctgctg gtgtaaaaat
    25981 cttagggaca acgatcgaag acttggatcg tgcggaaaat cgtgatttat tcgagcaagc
    26041 gctgaaagag ttggatattc ctcaaccttt aggggatact gctacaagta aagaagaagc
    26101 cgtggttatc gcttcgagaa ttggttatcc agttcttgtt cgtccaagct atgtattagg
    26161 cggacgtgcg atggaaatcg ttgaaaacca gcgagattta gaagattaca tggaacatgc
    26221 tgtgaaagca tctccagaac atccagtact agtggaccgt tacttgcttg gtggtgaatg
    26281 cgaagtggat gcgatttgtg acggtgaaac agtactcatc ccagggatca tggagcatat
    26341 tgagcgtgct ggtgtccatt caggggattc aatggctgtg tatccacctc aaacattatc
    26401 tgaatcgatc aagaaaacga tcgaagatta cacgatccgc ttagcattag gtttgaattg
    26461 tgtcgggatg atgaatatcc agtttgtcat ccatgaaaat gaggtttatg tgatcgaagt
    26521 caatcctcga gcaagtcgga ctgttccatt cttaagtaag gtgacaggaa ttccaatggc
    26581 acaaattgcg acgaaagcta ttttgggaga gaaactaaag acacttggtt atgaaaacgg
    26641 actttatcca gaaacaaaag aagttcatgt taaagcacct gtcttttctt ttacgaaatt
    26701 gcagaaagtt gatacttact tagggcctga aatgaaatcg actggagaag taatgggatc
    26761 tgacagacaa ttagacaaag ctttgtacaa ggcattcgaa gcttctggat tacacttgcc
    26821 tgaatatgga gccgtattat ttacgattgc ggacgaaaca aaagaagaag cactagaatt
    26881 agctaaacgt tttacagaaa ttggctatag tctgatagga acgaaacata cagctgctta
    26941 tttcgaaaaa aatggtctgg tcgttgaaac agtagcgaaa atttctgagg aagcagcaga
    27001 aaaaaatgta gtcgacttaa taagagatgg taaaacacaa gtggttgtca atacgattga
    27061 taaagatcgg ggaaatgctt ctaaagacgg tttcatcatc cgaagagaag cagttgaaca
    27121 tggtattcca ttgtttactt ctttagacac agcagatgcg atcgttcgag tgatggaatc
    27181 ccgtgctttt tcaactaacc ctatttaacg gcgagcacat gttaagacaa aaagacgaaa
    27241 aaccgttgca ggaggggaca gatgaaacaa gaaatgatgg aaatcgttca gcaaaaacag
    27301 ctggcaccaa agatttttga aatgacattg aaaggtgatc tagtaaaaga aatgcagcaa
    27361 ccaggacagt tcttgcatat tctcgtgccg cgtgcagact tgctattacg ccgaccgatt
    27421 agcttgaatc atatcgacca cgaaacaaat acttgccgta tcatttatcg ggtggaaggt
    27481 gaggggacta gagtcttctc tactctttct gccggagacc atttagatgt catgggtcct
    27541 ttaggcaatg gttttgattt gtccaatctt catacaggag acgaagtatt tataatcggt
    27601 ggaggaatcg gtgtccctcc tctatatgag ttatcaaaac agttagtcga aaaaggaatt
    27661 aagccaacgc attttttagg ttttgccaca catgaagtcg tttattatga aaaagaattt
    27721 aatcgtctag gagaaacaag aatcgctact gacgatggaa catacggtat gcacggaaat
    27781 gtcggtaatt tattgttagg aacgaagacg gaacctacag ctgtttttgc atgtggttca
    27841 aacgggttat tgaagacagt ggaacagctg ttttcttcgc atcaaaatgt ccagttatca
    27901 ttagaatccc gcatggcatg tgggataggg gcttgctatg cttgcgtttg tcatacgccg
    27961 gaagatgaaa caggaacaaa aagtgtgaaa gtttgtgacg aaggaccgat ttttaaaata
    28021 ggagaggtaa ttatatgaat gagaatcctt tagcggtcaa acttcctggc ctagaattaa
    28081 aaaatcctat catgccggca agcggctgtt tcggttttgg caaagaatac ggaaaatact
    28141 atgatttgaa tcagcttgga tcgatcatgg tcaaggcaac gactccaaat gcccgctttg
    28201 gcaatcccac gccaagagtg gcggaaacac catctggcat gttgaatgca attggtttgc
    28261 aaaatcctgg tctagacgtt gttatgcata aacttcttcc agaattagag gagtacaatg
    28321 agttacccat catcgcaaat gttgctggtg cttgtgaaga agactatgta gaagtttgta
    28381 gcaaaattgg cgaagcacca aatgtgaaag caatcgagct gaacatttct tgcccaaatg
    28441 tcaaacatgg cggaattgct tttggaacag attctgatgt tgcttttcaa ttaacacaag
    28501 cagtaaagaa agtttcttct gttcctgtct atgtcaaatt gtccccaaat gtaacagaca
    28561 tcgttccaat cgctcaggca atcgaagctg gaggggcaga tgggtttacg atgatcaata
    28621 ctcttcttgg tatgcggatt gaccttaaga caagaaaacc gattttagcc aatcaaacag
    28681 gtggactctc cggaccagca atcaagcctg tcgctattcg tttgattcac caagtagcaa
    28741 gtatatccag ccttccaatc attgggatgg gcggcgtgca gacagtggat gatgttcttg
    28801 agatgtttat ggctggagca agtgctgtag ctatagggac cgcgaatttc accgatccgt
    28861 atatctgtcc taaactaatt aaagagctcc ctgtgcgaat gagcgaacta ggcatcgaat
    28921 cgctggaaag attaatcaaa gaagtgagag aggaacgtga acgatgaatc aactagacca
    28981 acgaccaatt attgcattag atttttcaac taggcaagag gtagaagact ttcttcgatt
    29041 tttcccgaaa gaagaaaaat tgtttgtgaa aatcggaatg gaattgttct accaagaagg
    29101 acctgaaatc gtacgttatc taaaagaggc tggtcataat gtatttttag atctgaaact
    29161 tcacgatatt ccgaatacgg tcgaaaaagc aatgcgggga ttggcaaagc ttggtgttga
    29221 tctcacctgt gttcatgccg ctggcggtat tcgtatgatg gaggcggcaa tgcgaggatt
    29281 agaagagggg actccagaag gtggaaaacg tccgctactt ctagctatca ctcagcttac
    29341 ttctacaagt gaagaagaaa tgcatgccga tcaactaatc gaagtttctt tagaaaaaag
    29401 tgtgatccat tatgctagct gtgccaaaaa agcaggatta gatggtgtgg tttcttctgc
    29461 ttgggaagta gaagcgatca aagaaatggc aggagacgaa tttgtttgct taactccggg
    29521 tataagacca gaaggaacag tcgcaggaga tcagacaaga gtagtcacac cttctcaggc
    29581 aaaaaagatc ggctcaactt ttatcgttat aggtcgacca atcactcagt caactaatcc
    29641 ttataaagca tatcaaacga ttcaaacaga atggagctaa cctaaaatga atgttgaaca
    29701 aagtatcgca aaagacttat tagaaattga agcagtattt ttaaatccaa gtaatccttt
    29761 tacatgggca agtggaatca aaagcccaat ttactgtgat aaccgaatca cgatgagcta
    29821 tccaaaagtc cgaaaagaga tcgcaaaagg attagcaagc aaaatcaaag aagcttaccc
    29881 tgaagtacaa gtgattgctg gaactgcaac agcaggaatc cctcatgccg catgggtagc
    29941 ggaaatactg gatttgccaa tggtctatat tcgaagtaag gcgaaagatc atgggaaagg
    30001 taaccaaatc gaaggacgta tatttgaagg tcagaagatg gttgtgatcg aggatttgat
    30061 ttctacaggc ggaagtgtct tggaagcagc tgaagcagca aaaagagaag gtgcggatat
    30121 ccttggtgtt gcggctatct ttacgtatga gttgccaaaa ggaaaagcaa atttcgaaaa
    30181 agccgaaatc cctcttatga cgttgaccaa ttattctgta ttgattgaag cagctttaga
    30241 agatcgttat atcgatgagc aagaattaac tctgctaaaa gaatggaaaa aagatcctga
    30301 aaattggcag atttaagcgc gcttgatgaa gatagagaaa tccgatttgt gtctccagaa
    30361 tcatcaattg gaatagcaaa aatccaaaaa ctgattgcga gaagcatctt ttcatcaggt
    30421 atgaaaagaa acttctatcg tgatcagttt ttgatttttt taaaattcat ttttctaaga
    30481 ctggttagca gaaagaagag aataatctct tctctttttt ctattatata tagattttct
    30541 ctattttttg gtaagggagc tgtttcaaaa atggtaaaga gcggaaatgt tgcgaatatc
    30601 agttatttaa tgatatgata ttcggaaaaa gaaatctcaa agggaggtaa cttttatggg
    30661 gttgaatgaa tttattttag gattgaacaa tttagagacg atcacaaggg cacctggatt
    30721 ttttaaatat acagagcata cagttgcagc acattcgtat cgtgtagcat ctattgcgca
    30781 agttctagga gacattgaag aagcgaatgg acaaccgatc gattggaaac tgctctatga
    30841 aaaatcattg aatcatgact acacagagcg ttttattggt gatatcaaaa cgccggtgaa
    30901 atacgcaagc aaagagttaa gagggatgct gcaaacagtt gaagaaaaga tgacggacga
    30961 attcatcaac caagagattc cagctgagtt ccaagaagtt tatcgccgtc ggttgttcga
    31021 aggaaaagat gaaaccgtag aaggagaact attagccatt tcagataagg ttgaccttct
    31081 ttatgaatct tttgatgaaa tcatcaaaaa taacccggaa aaagtttata aggagatgtt
    31141 cattgaggca gtgactacga ttaaaagctt tgaacatcgg ccttctgttc agtatttctt
    31201 taaagagata tttccggaac tattgaacca ggaattttat ggaaaagagg cgtttttaga
    31261 aaccgtctca acgattgtaa agaaagaaga aaaataaaaa tgatatgaga tgcaggggga
    31321 agtatagttg aaaaagaata tggatgtcga atggggctat tctggagaca aaggtccgga
    31381 aaattgggcg agtttatgtg attggtttgc gagaggtgcg gaatttccat tgcagtcgcc
    31441 tattcatttg accaaggggg aagaaaccaa aatagaagga gacacgcttt cctttcatta
    31501 tcaaaagcaa cggtttactg acaaggaatt caaaaacacg attcatttag taccttttga
    31561 ccaactcagt tatgtagagt tcaagaaaga acgctattat ttgacagata ttcatttcca
    31621 cttgccttct gaacatatca tcaacggaaa acaggaagat attgaatttc attttgttca
    31681 tatgaacagc aaaaaagaga atctagttgt gggtgtcatg taccagctaa tggtacagga
    31741 aggttggctg tataatcaag aaaatgggga aagttggaac ttagaaaaac atgagcattg
    31801 ggtaaatccg gatgtgttct ttccggagca aaaaagccat ttccattata ttggctcatt
    31861 gacaactccg cctaccagcg ggccaatcca atggtttgta atggatcatg taggaaaact
    31921 gaaccaagag tttcttctcc ccttcgatgg tcagtatgct cgaccgaaca accgaccaat
    31981 ccagcccttg aatggaagag aaatttatta tttcgaggag tttgagcaat gaatattcag
    32041 cagatgaaat acgtggtcgc tgtagcaaac aatggtagtt tcagagaagc ggcaaagaaa
    32101 atgtttgtct cccagccaag tctttcagct ggtatcaaag aattagaaac cgagttaggg
    32161 atcacgctgt ttactcgaac gaatcgaggg gcatatttaa cagaagaagg gcaagacttc
    32221 ttaaatcgtg ccgagaaaat attggtccag cttgatacat tagaaactca ctatctaacg
    32281 agtgaaaaga gagacaattt ttcgatcgct gcccagcatt atgatttctt aggtcctttg
    32341 accgcacagc tactcgagga attcaaagac gagatcaaac aatttcggat catggagacg
    32401 acaacagcga gagtgatcga agaagtcaaa gagcagcaca gtgagatcgg cattatttat
    32461 atgaatgagc ataatcaagc tggtatcaga agatatttac aacaaggaga gctaagtggc
    32521 cgcagcattg gaaaattcaa aacgcatatt tttttaaggc aaggacatcc attagctgaa
    32581 cacgcagaga tcaccaaaga agaattgtta tcttatcctc aagttcgttt tacacaggat
    32641 ggaaataatt tcccgtattt ttatgaagac cttatcgaga tccctgatca agaaacagtg
    32701 atttatacga gtgatcgagg tactttgatg aatatcgttc ttgaaactga tgcttacgct
    32761 tcaggatctg gtattgtgat tggagggatt cgcgagcact tgcggttaat ccctttggca
    32821 gaaggcgaac taaatgaatt ttatatcatt tattcggcga aacgtccgct cagtgaaatc
    32881 gctcaaagat ttatcaaaga gcttactcgg ttactggacc agcagagcta agaaaagcag
    32941 atgagaacgc tgtttattga acaccgttga tcaaaaaaga ggggttgtga cagaattttg
    33001 tcacaactcc tctttttgta gcaaacaatt tataactaat tgctgttgtg ggaaagtacg
    33061 caaatatgat tctagaaaca ctcattgatt acctgttttg tttcatagct gtaatttttt
    33121 cttcttctgg tgtcacgata atcgtctttt ggttttcata aataacataa ccaggcttgg
    33181 cgccatttgg ttttcggata tgctttacct gtacaagatc aaccggcact tgggcagagt
    33241 atcggtattt tgaaaaatag gcagctaact cggcagcttc tgtaattgtt tcatctgagg
    33301 gcttgtcact tttaatgatg acgtgcgaac cgggtatatt ttttgcatga agccaatagt
    33361 cggttttttt agctgtcttc attgtcagct ggtcattttg aagattgttt ttaccaacaa
    33421 gaatgagcgt tccgtcagaa gaaaagtatt gatcaggctg agatggtttc ttacgttttt
    33481 gtttttttaa gttcttcttt ttcaggtatc cttctgaagt caattcttct ttaattgctt
    33541 cgatatccat tgggccggca atttccagtt gagataagac agattcaaga tattggattt
    33601 catctttggc ttcttggatt tgttcgccaa tcagcttaac agcgttcttc agcttttggt
    33661 atcgatggaa atatttctgt gcattttgat ttggtgtcaa tgccggatct agtgctattt
    33721 tgattggccg atcttcttca taataattag gtaaaacaac ttcttttgcg ccgcgtggta
    33781 cttgtgtcag aaaagtagta agtagttcgc catttctacg gtaattctca gcgttttcgg
    33841 attctttgag tgtttgttca cgttttttca atttattttt atttcgtttt agttcatttt
    33901 cgatttttcg aatcagttct ccgccttgtt gttttgcccg atctttctct gctttttcgt
    33961 gataatagct atctaataat tgactgagtg ttggataagc tgttacagca gatgcctgtt
    34021 cggacaatac ctgataagca atcggtgtga aaaaatcttt attttccgtt tcgtaaaaag
    34081 taggaatagg ctgatggctg atggctgaga aaaattcgtc ccatacaacc atcttttcat
    34141 taggacgttc cagtaatctt ttggtcagct cttgagcgat atcgaaaccg attccctgaa
    34201 actgacgttg gattgctttt ggatctagtt cagtttggga aagccgctga aagatttttt
    34261 ctttctcgga gctaaatggg ttcaagacct cttgttttgg cggagcaaca tattctacac
    34321 caggaagcaa agaacgataa gtgttttgag agcttccaat gtgtttgatc gcatccagta
    34381 tttttccagt ttctcgatta actaagacga tcgtactatg acgtcccatt aattcaacga
    34441 tcaatatgat attttgtaga tcacccaact cgtttcgttt agcaaagtgg aaatggatca
    34501 ctcgatcatt ttcgatttgt tcgatgtctt ctaaaatagc gccatccaaa tattttcgaa
    34561 gcatcatcac gaagttaggc ggattatcag gattctgata atcgatttgg gtaatctgta
    34621 cacgagcata acttgggtgc gcagataata ataatcgatg gtttttgccg cgtgaacgaa
    34681 tcaccagcac gatttcattt tcataaggct gatggatttt cgagatccgg ccagatagta
    34741 acgtttcacg caattcgttg accatcgcgt gggtaaatac accatcaaag gacatggttc
    34801 attcctcatt tcttttcata agtatattca ttataacgaa aaaaagaaga aaaaccaatt
    34861 tggccgaata gtaaagcaaa agtctagaaa aatcttggac taattacata aaaaacagtg
    34921 tttctatcgt tgaaatccaa atttttaggt ataataaaaa ataggagaaa aagtagaaaa
    34981 gaaggtgttt gttatttggg aagtagttaa atcgagagta caagaaatga atgaacattt
    35041 ctcagtgtca ttcgcagaaa atccaagtaa gtattttcga cgtcttgttt ttctgctcat
    35101 cttatcattg ctgttaacag ttgcaatgtt tttattgccg gaaaaaatcc gagaagagca
    35161 agtaaatagt ctcgtttatt cgtccatacc aaccagcaaa ttgaaacctt ttgattacag
    35221 caaagctgat cagaaaatca aacaaagccg ggcgatatcg gtgatgttca gcaaaccgaa
    35281 cgggaaaacc tatcaggaca tgcttgatgt ttttaatgat cctgagctta tggaagaatt
    35341 gaatcgaccg atcttttatt atccgatcgt ttatgatgta catgaactgg aacaaaaata
    35401 taacatacga acggatgaag tgacatttat tttctttgat ggaggaaaag aagcaaatcg
    35461 gataactgcg ggtaagggag gaataactga ttttgataag gagttgatcc ctgaactgaa
    35521 tcgacttccg ttagccaata tcaaacaatt agaagaagaa ttggatagaa cgggagtaac
    35581 ttcccaaaat tccgagattg ctaattgaga cattggcgcg atgaaacggt gggtctatat
    35641 agcgctattt ttaattatca gaacaagtga tgtttgatct tcaaaataac aaataaaaaa
    35701 ttaaaaaata tagttgacga aattcaaaaa ttcgattaga cttaaatcaa ttcttaagga
    35761 aagggtgacc tgtaatgaac ttatcaaaac gtatttcagc agaaaacaaa aaaaattggc
    35821 gcagctggcg tagataagtt gtattaatgg tgagactttc ccatagatac aactttttag
    35881 agtgcatttc taaagcttgt atctatgcta gacatgaaca ttgactgccg catagattag
    35941 aatctatgcg gttttttgtg taaagacaat gaccgctttg gccattgtct ttttttgtag
    36001 actggatact tgcctgatta taataaataa aaagattgac tttgcaggag gaaaaaaatg
    36061 aaaaacaaac gattaataac agttgtagta attattttag tttatttagc aggtgcattt
    36121 atttatggaa aagcctcagg cgaaaaagaa agtacttcga cgaaccagac aaaaaaaaca
    36181 acagttgttg gggtattgca atacgtgagc catccggcat tagatgagat ttatcgagga
    36241 atcaaagatg gtctgaaaga agaaggatta aaagaaggag aaaatcttga gatcaaattt
    36301 caaaatggac aagccgatca gagcaagcta gccacaatga gtcaacagct agtacaatct
    36361 gatccagatg ccttgattgg aatcgcaaca cctgccgctc aatcattagc aaacacgact
    36421 tcatcgatcc cagttgtgtt aggtgctgta acggatcctg tgggggctgg attagtcgct
    36481 tctttagaga aacctggtgg taatgtaaca ggtgtttctg atcagccgcc tgttacttca
    36541 caaatcaagc ttgcttctga tttgttgcca aatgcaaaaa aagtcggaat cttgtatgct
    36601 tcttcagagg ataattcaaa ataccaagta gcacaagcag aagaagctgc aaaaaaagaa
    36661 gggttagaat cagtaaaata tgcggtgcct tccactaatg agattgcaca aacggttcaa
    36721 gtgatgagcc gacaagtcga ttttatctat gttccattag ataataccat tgccaatgcg
    36781 atgcaaacag tggtaaaaga agcaaacaaa gcaaatatcc ccgtcattcc atctgtggat
    36841 acaatggtgg aacaaggtgg actagcaaca atcgggatca atcaatatca attagggctt
    36901 caaagcggta agatggcggc agaacttgcg agtggaaaag aaaaaccgga aacgacgcct
    36961 gtttatacat ttgatcaagg ggatacagtg atcaatcaat ctcaagctga tcgcttagga
    37021 atcattgttc cccaatcgat gaaggaaaaa gccaaaatca ttacagatga ctcgcagcaa
    37081 gaaacatcta aggaggatga caaatgatcg tatcagctat ttcacaaggc atgctttggg
    37141 caatattagg attagggatt ttcatgactt atcggatctt agactttcct gatatgacga
    37201 cagaagggtc cttcccatta ggtgctgctg tctgtgtgac agctattact catggggtag
    37261 cgccgattgt agctacatta ttaggcgtag gtgctggcat gatagcagga ctcgttacgg
    37321 ggttacttta tacaaaagga aagataccgg ttattttagc agggatttta gtgatgtcag
    37381 gattgaactc agttattttg tttgtgatgc gaacaccaaa tctttcttta ttgaatcatc
    37441 cgattctaca agacagcttc catcgctttg ggttacctga ttactttgac acagtccttc
    37501 ttggcttcat ctctttgggc atcttgattg ctgtactgct attcttcttc aatacagatt
    37561 tgggtcaagg ctatattgcg acaggagaca acgaaacgat ggctcggtcg ttagggataa
    37621 aaaccgatcg tatgaaaatt ttaggtttaa ctttgtcgaa cggtgtcatt gcattatccg
    37681 gtgcgctgat tgcccagaac gacggatatg cagatgtaaa taaagggatt ggcgtaatcg
    37741 tcatcggtct tgcttccatc atcatcggtg aagtgatctt ccaagaattg acgctagcag
    37801 aaagattgat tgctattgtt gtcggcagta tcatttatca gctattgatt ttagtagtaa
    37861 tcaaactagg gtttgacacg acttatctga agttgttctc cgctatcatc ttagctattt
    37921 gtctgatgat cccgcaattg aagaaagcac tgaacttaaa aacgggtttt gagaaggagg
    37981 catagtaatg actgatatat tgacaatcaa aaatggcaga aaagtcgtaa acaatggaat
    38041 gaatgaagag aaagtactat tggatgaaat taaccttaca atcagagaag gggacttcat
    38101 cactgtcctt ggcgggaatg gtgctggaaa aagcacactg ttcaatacga tcgctggtac
    38161 gcttcaactc agtcaaggat cgatctcttt taaagatcag ctgatcacaa aagattcaga
    38221 agaaaaaaga gcacgattcc tttctcgagt tttccaagac cccaagatgg gaacggctcc
    38281 tcggatgaca gtagcagaaa atttgctact tgcacaaaaa agaggtcaaa aacggaaatt
    38341 ccgtttacgt aacttgaaaa atcaaaaaga agattttttc agactatgtc aagaagtcgg
    38401 taatggccta gagcaacact tggatactcc agcgggtgaa ttatctggtg gtcaacgcca
    38461 agcattaagc ttgctgatgg cgacgatcac agctcctgag ttactattat tagatgaaca
    38521 tactgcagct ttagatccta aaacagctaa agcattaatg cgattaacaa atcagcggat
    38581 caatgaacaa aaattgactt gtctcatgat cacgcatcga atggaagacg ccttgaaata
    38641 cggaaatcgt ctgatcgtac tccaaaaagg gaaaatcgtt caagatattt ctgaaaaaga
    38701 aaagcaacat ttgacaatgg gcgacctttt gcagttcttt gaagaagtag tggattgatt
    38761 tcgacagaaa aattcctttc agtagaagga cttgaaaact cattgacatc ttcctttgat
    38821 tcatcctata cttaaaacaa taaacaatta aacatatttg ggtgttttgt aggatcacgt
    38881 agtcaatgat tttaacaatt aaatagaata ttctttgctc tgacaagtaa acgatgagaa
    38941 aagaatttgc tactttgcca cctagacgtt tcgtactttt tcgtatcaaa cgctaagtgg
    39001 ctttttttat tgaagtaaga acaaaggagg aataagatga tttctggaca aaccaaatta
    39061 gctgggctct ttgctgatcc ggcttctcac agtttatccc cattgatgca caatactgct
    39121 tttgaagcaa acaacatcga tgcggtgtat ttagctttcc aagtaaatcc aatgaatttg
    39181 aagcaagcag tcgaaagtat tcgaactttt gatatgttag gtgtaaatct ttcgatgccg
    39241 aataaaacag cggttattcc ttatctggat gaggtaagcc aggaagcgca attgatcgga
    39301 gcagtgaata cgatcgtgca cgaaaagggt cgtttgattg gctataatac tgatggtgcg
    39361 ggcttcatgc aatccgtgca agaagctggg atttcgatca aaaagaaaaa aatgactcta
    39421 ctgggagctg gaggtgcagc aaaggcagtc actgttcaag cagcgttaga cggcgctgag
    39481 gaaatcgtag tttataaacg aaacaaccaa acattcgctc aagtaaaaga aacattcgaa
    39541 caactcagct atcgaacttc ttgtaagata aaagttcgtg actttgccga tacgcatcaa
    39601 ttaagaaaag acttgaaaga aagctgtctt ctagtcaatg caacagatat cgggatggga
    39661 aagaaaatca atcagtcacc gctcttagat ataagcatga tgcatgagaa tctagcggtt
    39721 tttgatttga tttatgcacc tagagaaaca cgtttattaa aagaagcaaa aaaagtagga
    39781 gcaaaaggat acaatggact tggcatgttg atctaccaag gagcaatcgc gtttgaatta
    39841 tggacaaagg aaaagatgcc gatccatgtg attgaaaagc tgtttgatta aaaaaggata
    39901 atagataaag atcttttatt ctcgcataaa cggtctcaag aaaagtaatc ctttatgtat
    39961 cgaagcattt atttcgttat tttttattaa attatcaaaa aatgataggc ttttgtcgat
    40021 tggttatcgt atcctttatt tatcagtaag aaacgaggag gaaccacaat gagtcggatg
    40081 gatcgctata aggacatcca taagaaggcg aaacctctga agcgggatac ggggagtatt
    40141 tttgctagaa gagaacgaaa acgaacgcgt atggaaaatg aggaagatgc tacccgtatt
    40201 tatgaaagag agcagcattc atttgaacat ttgaaccaat acgagcaaca gatatacaga
    40261 gatgcaccaa gagcagaaga acaacaaaaa aataaaaaat ttttcaatcg gcaaaagaag
    40321 aacaaaccgt taaaacctcg aagaaagcga tcgtggaaaa aaatcattct atcgattttg
    40381 cttgttttga tcctttattc aggtatctca ttttttattg gtaaatatgt agctgaacat
    40441 gacacaagct tagaggcagc gacttcagaa acctttcatg ggcaaaaagc gacgaatggt
    40501 gcgcataata ttttgatcct tggaagtgat acacgcggag aagatgccgg gcgagccgat
    40561 acgatcatgg tcttacagtt ggatggtcct tcccataagc cgaaactgat ttcttttatg
    40621 cgtgacagct tcgttacgat cccaggggta ggacaaaata agatcaattc agcttatgca
    40681 tacggaggag ccgatctagt gcgtcaaact ttagtagaaa attttggaat cgattgtcaa
    40741 tactatgcga aagtcgattt caaatcgttt gaaaaagtga tcgatgcctt attcatgaac
    40801 ggagtgaaga tcgatgcaga aaaagatctg aatctggatg gtgtagatat taaaaaaggg
    40861 ggccagaaga tggatggaca tgttcttttg cagtacgcac gtttccgaat ggatgaacaa
    40921 ggagactttg gccgtgtcag acgccaacag caagtaatga acgctatttt cagccaattg
    40981 aagaatccat tgaatctgat ccgtgcacct tatgcagctg gtaaagcttt aggatataca
    41041 tccacagatg tcactgcttg gttcttgacg aaaaacctct tttcgattgc acgaggagct
    41101 ggtggcattg atcgaataag tgtgccagta gacggttcgt ggaattatgg gcaaagtgat
    41161 tatgctggca gtattcttga aattgataat caaatgaatc aatctgctat tacagatttt
    41221 ttgaataaat gatcataaaa aagatcaaga agaagctgcg caaggctttt gtcatgaatc
    41281 aatcaaacga ttcactcgta aaaaacgctt tcttatggta gatttaacca agagaggagc
    41341 tgtttacatt ggatatctat ctgaacttca aaaatgagtc gcgtgaagcc atcgcttttt
    41401 atgaaaaagt ttttcagact gaagcatcag gtatcaccac atacggtgaa atgcctggaa
    41461 tagaacaaat gaacttgcca gaagaagcaa aaaatctaat cacgaatgca cggctgaaca
    41521 tttatgatac attagttatg tttgcagata cgccagaagg aattggtcct gaattagttg
    41581 tgggaaataa tgtttcttta gtcatccaga caagaaatga agaagaaacg aagcgcctat
    41641 ttgaaagctt agctgagggt ggtaagattg agatgccact ggatgctgtt ccgtgggctc
    41701 agttgtatgg gatggtaact gatcgatttg gcatcaactg gcagattaac caagagtgac
    41761 agctaaagat gaatattttc tggaaacatc aagcagcaaa cggatcatcg tttgtttgct
    41821 tgatgttttt gtgtctattt cgactatacg gtatcttttt tttattgcca gatgcgaaaa
    41881 tatgttccat aatagagaag tccgcaaaaa attaagtaac ggaggtcaga agatgaagac
    41941 ggtgatacta gctgaaaaac cttcacaagc aaaagcctat gccgaaacct tccaacagca
    42001 aaagcggcat gaagggtatt atgaaatcag cgatccattg tttgctggtg aagtaaccat
    42061 cacttatggt tttggacatt tggtagatat ggttgctcca ggagcttatg aagagcgttg
    42121 ggcaaaatgg tctttagaaa atttgcctat tttcccagaa accttccgtt acgaagttcc
    42181 aatggacaaa cgtgcacaat tttcgatcgt aaaacgagaa ttgcagtcag ccgataccat
    42241 cattattgca acagatggtg atcgagaagg tgaagccatc gcgtggtcga ttattcgaca
    42301 agcaaacgca ttttctaagg aaaagaacta tttacgttta tggatcaatt ctcttgaaaa
    42361 agaagcaatc tatgaaggtt ttaagaatct ccaacctgga aagaactatt ttccaaaata
    42421 taaagaagcg caagcaaggc agaacgctga ttggctgatt ggaatgaatg gaagtccatt
    42481 atatagcttg ctacttcaac gaaaagggat tgatggcagt ttttctcttg gtcgtgtaca
    42541 aacaccgaca ctctatatga tttatcagct gcaagaagaa atcaaacact tcaaaaaaga
    42601 aacgtacttt gaaggagaag gtttaattac gacaaacaaa gggcagtttt ctggaaaaat
    42661 cgtaccaaaa aaagcattta aaacccaaga agagttaacg aaggaaatag aaaaacttgg
    42721 agcgcattta ggtaagcaaa acggacggat tcttgaagtt acgaaaaagg aaaagaggtt
    42781 gcatagtcca cgtttatttt cgctatctag tttgcagaca aagatgaatc agctaatgaa
    42841 agcaagtgcc aaagctacac ttgatgctgc tcaaggattg tacgaaagca agtttctaag
    42901 ctatccaaga acggattcct tttacattac agaaaatgag catcagtatc tggttaaaca
    42961 tctgcaaaat tataaaaaat ttttaggaat agaagaagta cagacaactg agatcaaagc
    43021 aaagaaacga tatgtcgatg cgaaaaaagt tcaagaacat catgcaatta ttccgacaaa
    43081 gacgattccg actcctgcac gctttgcgaa gctttccaaa ttacagcaag caatctattt
    43141 gcaagttttg cgcactactg tggctatgtt tgctgcagat tatatctacg aagagacgac
    43201 cgtaatgacg ggcgtacagc aattaaagct aaaaagcatc ggaaagatcc cattacagca
    43261 aggttggcag gaaatcttac gcatcaagtc aaaaaagaaa gaagctcaga ctcttcctcc
    43321 tatcgtagaa aatgaagaag cagaagtaga actgaaaagt atggagaaag aaacacaacc
    43381 tccaaaaccc tataccgaag gaacgttgat cacagcaatg aaaactgcgg gaaaaacgct
    43441 ggataatgat gaagcgcaag aaattctcaa agaagtagaa ggaataggga cagaagctac
    43501 acgagccaat atcattgaaa atcttaagca gaagcattac atcgaagtca ataaaaacga
    43561 aataactgtt acgccaaaag gaatcactct ttgtaaggca gtagccaatg aaccattact
    43621 gacgagcgca gaaatgactg cgcgctggga agggtacttg agaaaaattg gtaaacaaga
    43681 ggggacacca tctgtttttt tagagaatat caaaaaattc atcctacatt tattggcaga
    43741 agttcctaat caaatcgaca aggtagactt ttcagatgag attagcggga cacgtcagat
    43801 aaaagcgatg gagaagaaaa acgatcaatt aggaagatgt ccaaaatgta aaaagggaat
    43861 agtcatgctt tatcctaaaa tcgctacatg cttgaatccg gaatgcgact tcaaattgtg
    43921 gccaacagta gctaaaaaga agctgactaa aacgaatctc agagatttgc tttcaaaagg
    43981 aaagacaagt aaagttgtca aaggttttac tggtaaaaaa gggaaattcg atgcagtttt
    44041 agtattaaaa gaagatatga caatcggttt ttcttttcca tggatcgaaa acagtggaac
    44101 aaaagcagtt gatggaaaca aagaaacatc aagaaaaaat aatgaaaacg aagtagagta
    44161 aatgaaaaca atgaaatagc ggaatattta ttccgaaaag tgagaatata aataccaata
    44221 aaactaaaaa atatcagtga atcaagcaaa aacgttgggg taggctgatt ttatatagat
    44281 agcaaggagt ttttttattt gaaaaaagtg cattcatttt taaattatct tatgggagca
    44341 atcacgattg tggctgtgta ccaagcattt ctaaagtatc ctgattacgg gacgaagttg
    44401 ttgtcattga cgcacaatca aacagcatat tcaccaacgt tgattttatc gactttgact
    44461 gcaggagcta aaagcgctac ttattttttt cataaaacga caagcatgct aaagcgaaag
    44521 aaacagcgaa aacaattgtt ggtggtggta gcggctatga tcattattta ttttctacca
    44581 gttattacac aagtatttca tcaatatttt ggttaagaat acgagagttt gtgacaaaag
    44641 tcatgtcaca aacttttttc tttgtcattt tttcgtaaga aaaagcaaaa taaaagtata
    44701 tacattgatt aaaagtatat acttggatat aatgtactta ctatagaatg agaatggtat
    44761 agagggtggc gaaatatgaa aaaaatgaaa aagtataaaa ttagaaaatc tggcaatagc
    44821 gatgtaacaa ctatcccacc agaagtaaaa gaattcatgg gtgtgcagac aggtgacgca
    44881 atcagttatg tttttcaatc tgatggttct gtacgaatga tcaaagcaca agaagaacct
    44941 gatattgatt cattagttga ttcgatcatg aatcaatatg aagacgcgtt aaaagatttg
    45001 gttgatttat gaggtatctt tcgactaaag aaattatcaa aatcaacgcg aaagttattt
    45061 taccgtcact cgccaggcga aatgatcggt gtaaaagatg caaatgcatt agatatggcc
    45121 gtcaaacagc cttcacaagc agtattcaat caagaactct atcctgaaat ctatgaaaaa
    45181 gcggcgattt tagcaattaa tttagctaaa aaacatcctt ttcataatgg caataaacga
    45241 actgctcttg ttgccatgtt gttgtttctt caattgaata attgtccagt tgctttttct
    45301 cgtcaagaag ctgttgattt tatcataatg attaccacta gttcattgga tttcgattca
    45361 ctaaagtcca agataaccag ttatttacga caaaccgcaa taaaatgaac gaattaaaaa
    45421 ctttatttct caattagatc agcatgtcat taaggaatat gctgattttt ttatgtttaa
    45481 tcatacaaaa tag
//
LOCUS       DAZKCH010000012        45325 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000012 DAZKCH010000000
VERSION     DAZKCH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.012"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(9..1644)
                     /locus_tag="ACG84X_000711"
                     /pseudo
     CDS             complement(9..1644)
                     /locus_tag="ACG84X_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1967..2446)
                     /gene="rlmH"
                     /locus_tag="ACG84X_000712"
     CDS             complement(1967..2446)
                     /gene="rlmH"
                     /locus_tag="ACG84X_000712"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFP9126610.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            2874..4163
                     /locus_tag="ACG84X_000713"
     CDS             2874..4163
                     /locus_tag="ACG84X_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFP9126611.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(4202..4807)
                     /gene="ytpR"
                     /locus_tag="ACG84X_000714"
     CDS             complement(4202..4807)
                     /gene="ytpR"
                     /locus_tag="ACG84X_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFP9126612.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(5012..5476)
                     /locus_tag="ACG84X_000715"
     CDS             complement(5012..5476)
                     /locus_tag="ACG84X_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFP9126613.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(5498..5818)
                     /locus_tag="ACG84X_000716"
     CDS             complement(5498..5818)
                     /locus_tag="ACG84X_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFP9126614.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(5962..7041)
                     /gene="pepA"
                     /locus_tag="ACG84X_000717"
     CDS             complement(5962..7041)
                     /gene="pepA"
                     /locus_tag="ACG84X_000717"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFP9126615.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            7241..7591
                     /locus_tag="ACG84X_000718"
     CDS             7241..7591
                     /locus_tag="ACG84X_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFP9126616.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            7814..8761
                     /locus_tag="ACG84X_000719"
     CDS             7814..8761
                     /locus_tag="ACG84X_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9126617.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(8818..10236)
                     /gene="pepV"
                     /locus_tag="ACG84X_000720"
     CDS             complement(8818..10236)
                     /gene="pepV"
                     /locus_tag="ACG84X_000720"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFP9126618.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            10385..11230
                     /locus_tag="ACG84X_000721"
     CDS             10385..11230
                     /locus_tag="ACG84X_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFP9126619.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            11234..11674
                     /locus_tag="ACG84X_000722"
     CDS             11234..11674
                     /locus_tag="ACG84X_000722"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFP9126620.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            11724..11918
                     /locus_tag="ACG84X_000723"
     CDS             11724..11918
                     /locus_tag="ACG84X_000723"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126621.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            12054..12740
                     /locus_tag="ACG84X_000724"
     CDS             12054..12740
                     /locus_tag="ACG84X_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9126622.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IQEALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(13148..13837)
                     /locus_tag="ACG84X_000725"
     CDS             complement(13148..13837)
                     /locus_tag="ACG84X_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126623.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(13812..15941)
                     /locus_tag="ACG84X_000726"
     CDS             complement(13812..15941)
                     /locus_tag="ACG84X_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFP9126624.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(15989..17326)
                     /locus_tag="ACG84X_000727"
     CDS             complement(15989..17326)
                     /locus_tag="ACG84X_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFP9126625.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(17578..17937)
                     /gene="rplT"
                     /locus_tag="ACG84X_000728"
     CDS             complement(17578..17937)
                     /gene="rplT"
                     /locus_tag="ACG84X_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFP9126626.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(17990..18190)
                     /gene="rpmI"
                     /locus_tag="ACG84X_000729"
     CDS             complement(17990..18190)
                     /gene="rpmI"
                     /locus_tag="ACG84X_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFP9126627.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(18262..18786)
                     /gene="infC"
                     /locus_tag="ACG84X_000730"
     CDS             complement(18262..18786)
                     /gene="infC"
                     /locus_tag="ACG84X_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFP9126628.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(18830..18955)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            19106..19738
                     /locus_tag="ACG84X_000731"
     CDS             19106..19738
                     /locus_tag="ACG84X_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFP9126629.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(19740..20645)
                     /locus_tag="ACG84X_000732"
     CDS             complement(19740..20645)
                     /locus_tag="ACG84X_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFP9126630.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(20730..21389)
                     /locus_tag="ACG84X_000733"
     CDS             complement(20730..21389)
                     /locus_tag="ACG84X_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFP9126631.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            21705..22649
                     /gene="mvk"
                     /locus_tag="ACG84X_000734"
     CDS             21705..22649
                     /gene="mvk"
                     /locus_tag="ACG84X_000734"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFP9126632.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            22642..23619
                     /gene="mvaD"
                     /locus_tag="ACG84X_000735"
     CDS             22642..23619
                     /gene="mvaD"
                     /locus_tag="ACG84X_000735"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFP9126633.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            23632..24717
                     /locus_tag="ACG84X_000736"
     CDS             23632..24717
                     /locus_tag="ACG84X_000736"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFP9126634.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            24714..25778
                     /gene="fni"
                     /locus_tag="ACG84X_000737"
     CDS             24714..25778
                     /gene="fni"
                     /locus_tag="ACG84X_000737"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFP9126635.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26027..26830)
                     /locus_tag="ACG84X_000738"
     CDS             complement(26027..26830)
                     /locus_tag="ACG84X_000738"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFP9126636.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(26850..27692)
                     /gene="kduI"
                     /locus_tag="ACG84X_000739"
     CDS             complement(26850..27692)
                     /gene="kduI"
                     /locus_tag="ACG84X_000739"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFP9126637.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(27708..28715)
                     /locus_tag="ACG84X_000740"
     CDS             complement(27708..28715)
                     /locus_tag="ACG84X_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HFP9126638.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(28722..29366)
                     /locus_tag="ACG84X_000741"
     CDS             complement(28722..29366)
                     /locus_tag="ACG84X_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFP9126639.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(29466..30224)
                     /locus_tag="ACG84X_000742"
     CDS             complement(29466..30224)
                     /locus_tag="ACG84X_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFP9126640.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(30351..31502)
                     /gene="fucO"
                     /locus_tag="ACG84X_000743"
     CDS             complement(30351..31502)
                     /gene="fucO"
                     /locus_tag="ACG84X_000743"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFP9126641.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(31584..31895)
                     /gene="rhaM"
                     /locus_tag="ACG84X_000744"
     CDS             complement(31584..31895)
                     /gene="rhaM"
                     /locus_tag="ACG84X_000744"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFP9126642.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(31897..32742)
                     /gene="rhaD"
                     /locus_tag="ACG84X_000745"
     CDS             complement(31897..32742)
                     /gene="rhaD"
                     /locus_tag="ACG84X_000745"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFP9126643.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(32756..34012)
                     /gene="rhaA"
                     /locus_tag="ACG84X_000746"
     CDS             complement(32756..34012)
                     /gene="rhaA"
                     /locus_tag="ACG84X_000746"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFP9126644.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(34009..35469)
                     /gene="rhaB"
                     /locus_tag="ACG84X_000747"
     CDS             complement(34009..35469)
                     /gene="rhaB"
                     /locus_tag="ACG84X_000747"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFP9126645.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            35622..36491
                     /locus_tag="ACG84X_000748"
     CDS             35622..36491
                     /locus_tag="ACG84X_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFP9126646.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(36617..37516)
                     /locus_tag="ACG84X_000749"
     CDS             complement(36617..37516)
                     /locus_tag="ACG84X_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126647.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(37681..38505)
                     /locus_tag="ACG84X_000750"
     CDS             complement(37681..38505)
                     /locus_tag="ACG84X_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFP9126648.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(38516..39811)
                     /locus_tag="ACG84X_000751"
     CDS             complement(38516..39811)
                     /locus_tag="ACG84X_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFP9126649.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(39827..40306)
                     /locus_tag="ACG84X_000752"
     CDS             complement(39827..40306)
                     /locus_tag="ACG84X_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFP9126650.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(40312..41340)
                     /locus_tag="ACG84X_000753"
     CDS             complement(40312..41340)
                     /locus_tag="ACG84X_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFP9126651.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(41357..42463)
                     /locus_tag="ACG84X_000754"
     CDS             complement(41357..42463)
                     /locus_tag="ACG84X_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFP9126652.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(42692..45289)
                     /gene="adhE"
                     /locus_tag="ACG84X_000755"
                     /gene_synonym="adhC"
     CDS             complement(42692..45289)
                     /gene="adhE"
                     /locus_tag="ACG84X_000755"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFP9126653.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
BASE COUNT        13114 a         9654 c         8239 g        14318 t
ORIGIN      
        1 aaatgtaatc agatcattat ttttatatgt tgtaacttcc tgataagaaa actaattaaa
       61 agaaagaggt aactacataa actaattaaa aaagctaact tcatagttgg aggataaatg
      121 gaagaaactt caatgattgt ttctccttgt gttccttcaa tcgacactag tcctattatc
      181 aatctctctt ttttgtccat ttacttttgc gactgttccc caataatcaa atacaggaag
      241 cgttattttt tgtcctttag attcatgtac tgtatagact attttcgaat ccatcacttg
      301 ataaggcata gtatgccatt ccttgccaat tcttacttca tgattctgca aatgttcttt
      361 gtattgtaat gcttccgtgg gtgcatagtc ataaagtcct ccgggaagga gtgtcgtgta
      421 acgaataaga ttttcttgat tcattaccaa gtgatctctc tgagtgacaa ctttatgttc
      481 atagtttgct tttgttgcag cagatacagc caacagtaat aaaacaattg ccgttatatt
      541 aactactttt ctttgcttag ctgatgtgct cttcatgaaa acgaacgata aaatcaacga
      601 gccaaacagt acttgaaagc ctaagattcg ccaaggaaat tgaatcattt gaatgggtgt
      661 attttgtaat aaagaccatg gaaaaaattt ggtggataag agccaagaga ctaccgcact
      721 aaggtaaatc actttttctt tgcgattaaa tcctttaaaa aagaagagtg gacagatcaa
      781 agaaataata ccaatgattc ctaccgtaaa ggttgtcagg tcattattca tcgcaccaat
      841 caaactatcc gagacattta atgcttggtg ttgtaaggtc gttttatctg gctcattaat
      901 cgattgaacc atgatttgtc ggaacatcgg ataccaaaag tatgctgtta aaagaatcgt
      961 cattcctact gcctttgaca actccacaat caaccggatg ctttcttttt ttcttgtttc
     1021 acttactaca aagccgccta agactagtaa gccaacggct attacactca taaaagtgga
     1081 aagaacatgt gtataaatga gtaagctcat actgactgct aatggaattg cacatggctt
     1141 tttctcataa atcagtgcgt aagcataata cataactatc ggtataaccg taagtgcaat
     1201 cgcttcagca atagcagaac gatgataaat atcaatcgta cggtacccat aaaatgtata
     1261 taaacagcta aatataaaag ccgcatcgat tctttttaaa aattttagtc cataatgaaa
     1321 catcagcatg atagtacaaa cattcaatag ccaaacatat aagatataac taacgattaa
     1381 attattactt atccaataaa aaatgactgc cggaaaaaag gtcaagtagg gataaaaata
     1441 attcactccg ctcccataat gattaaacgt cgtaaaattg attggaccag aaaaaattga
     1501 agataaccct ttgactctag caaaatggaa ggcaatatcc cccgatgtag aaatagtatg
     1561 aacatttcta aaataattga ttgaataaag tccagcaata attgctagga gaatggacaa
     1621 tattattttt ttctttactt gcattactta attatatact cctttcatgg attgctttat
     1681 ctagtataac ttaaatttta aataaatcgt tatttatttt tactctcact taaaaaagca
     1741 ctaaaattat aagagaggga ggtaatggtc tgaacaccaa gaattgttcc aacatcgaat
     1801 tgcttaacta atgagttcaa agcttaatta tgtggctctt atatttaccg agcgtggatt
     1861 gcgatctctt tagcgaaaca aacatctttc ataaaaaaaa cagccatatc cgctttcttg
     1921 gatatgacta tttactacta ctttactatc tttcattctt cttgtctcac ttatgataag
     1981 gcgcccccgc attgatccgg aaggcacggt agatttgctc gacaaggatc agacgcatca
     2041 attgatgtgg atacgtcatt tttccaaaag agatctgagc attgcttctt ttcatgacgg
     2101 cttcgctgag tcctaaagag ccgccgataa caaaaacaag gtggcttttt ccttggatac
     2161 ctaattggtc gatttgttta gcaaaagatt cacttgtagg atttttccct tcaattgcta
     2221 aggcatagac gtattcttgt tctttgattt tcgctaagat ccgttcccct tctttttctt
     2281 ttacttgtct catttgcgct tcgcttaaat tctccggggc tttttcgtca ggaacttcga
     2341 tcaattcgat ttttgcatag gcattcagcc gtttgacata ctcattgata ccttggatca
     2401 ggtatttttc ttttaatttt cctactgaga taattttgat attcatgttt tctctccttt
     2461 ggtcttcatg ctcactttgt ttattataat caattttttc gtctatatgt ttattttggc
     2521 tatttttgtt aaaaagattt ccccaacagt tatgcacaac atccacaggt ttatccacag
     2581 aaaacagtgt tattttacct tatttcatca cattcattag gcaaacatac gttttataag
     2641 aatttatcca ctttatacac aggctgtgga tatgttttat cccttatttt tccaatccta
     2701 tccgcgtagt tttacacagt atctgtggaa aaagaaaatc aaatattttc atctgaaaac
     2761 aatgattttt cctaaagttt ttcataaaaa gttcacagtc tcaaagtaga ctaaagtcaa
     2821 caaataagac tatactaaca gtagataaat gaatgtaatt ggaggaggaa cacatggata
     2881 gaaaaaatgt gacaccaaag atgaaaaaaa gtaaaaataa tagcctctgg cgtaagttag
     2941 gtctggggct tgttggaggg atcgttggag gactactgac agctggcatt ttttatgcag
     3001 cgatgggcac tggcaacaat agttctactg ctacaagcgg caatcagaat tctgccggtg
     3061 aaacagttgt ggaaaatgtc aaagtcaatg tagattctga tatcaccaaa gcggtagata
     3121 aagttcaaga cgctgtcgtt tctgttatca acttacaaag tcaaaaccaa tcaagcggtt
     3181 ttggcggact attcgggcag caagaagaaa gtagcagctc agatgatagt aatttggaag
     3241 cttatagtga aggaagcggc gtgatctaca aaaaagacgg gaatactgct tatgtagtca
     3301 cgaataatca cgtagtagat ggccagcaag gtcttgaagt cttgatgaaa gacggtacga
     3361 aggtaaaagc tgaattagtt ggaacagatg cttattcaga tttagcggtg ttgaagatca
     3421 attcagacaa agtcgaaaca gttgcctctt ttggtgactc aagtgctctg aaggttggtg
     3481 agcctgcgat tgcgattggt tccccactag gatctgaata tgcaaattct gtcacttcag
     3541 gaatcatttc ttccttgaac cgacaagtga caagtacgaa tgaatcgaac gaaacagtca
     3601 atatcaatgc gatccaaaca gatgcagcaa tcaaccctgg aaattctggt ggtcctttag
     3661 ttaatatcga aggacaagtt atcggtatca actcaagtaa gatcgcaagt acttctgaat
     3721 ctacttctaa tgtaagcgta gaaggaatgg gatttgctat tccaagtaac gatgtagtga
     3781 atatcatcaa tcaactggaa aaagacggaa aagtgacacg tccagctcta ggtatcacaa
     3841 tggtcgactt atctgccgtt tctactcagc aacaagaaca aatcttgaag attccttcat
     3901 ctgtaactaa cggtgtcatc gtgacaaatg tccaaacagc tacaccggct gaaaaagctg
     3961 gattgaaaca atacgacgtc attactaaga tcgatgacaa agaagtttct tctggtgtag
     4021 aacttcaatc tgctttgtat aagaaaaaag tgggagattc tgtcaaaatc acttactatg
     4081 aaggctcgaa agaaaaaaca actactgttg aattgacgat cgatcaatcg gcattaaaac
     4141 aaaatcaaaa tagtgaaaat taataaaaaa gaggttgtga caaagacttg tcacaacctc
     4201 tttattttgg aaatgcttct ccgactacgg catcctcagg caatactaag attccttttt
     4261 ttgctggagc atttggcaaa tgcaattcac gagcggaaca gatcattcca tagctatcta
     4321 cccctcgcaa agttcctggc cagatcatca ttccatctgg catcatagct cctggttttg
     4381 caacgacaac tttttgtcca gcttcgatat tgggtgcacc gcaaacgatt tgcaatactg
     4441 taccattgtc tacttctgtc tcagtaatcg ataaatggtc agaatcagga tgtgggacgc
     4501 atgtttttac gtacccgaca acgatcttcg gttcatgatc agcttcaagc tgttcttcga
     4561 atcctgcttc tttgatcaat cgattcaatt tcgctaattc ctcatctgtt aagcttactt
     4621 ggccgttccc ttcgattgtt agatgatcgg agatatggaa aaagttccaa gcaacaactt
     4681 gaccttgttc atctttgatc cgagcaacat tccatttgcg ttcaacagtg ttttctgttc
     4741 ctttatcgtc ggctataata accatcaagg tgtctccgac gtgtgctttg ttataagcaa
     4801 aaatcatgtt ctttcctcca ttatcctttg ctgagattta tcttaacaaa aaattgcatt
     4861 cactgcatga aatttttttc atgctttatt tccgaagaag cctcttctgg aacaccattt
     4921 attcgtaaca agggactgtg acaagacttt tgtcacagtc cctttactgt tttagttaat
     4981 tgattaaaaa ggtcgtacaa gttccacttg cttaattact tggctgttct tcttcgtcag
     5041 aaacgatcaa gacatcacaa ggtgaatgac gtatcacgta gctggctaca cttcctgtca
     5101 taaagcgttc gactgcattt agacctgact gcccaaccat gattagatcg atctcatatt
     5161 tttttggcaa tttgactgcc atggattcac gaacagaacc atatgcaata attccttcta
     5221 tatttgtgta atcaacagat ttcccatatt ctttacattc ttcgatcatt tccttggctg
     5281 tttcagtttg ctgatcgact agattttgat caataggtgc atagcccata aagttataaa
     5341 attgctgatc gattacgttt gctacatata ctttcccatt attacggcga gccacttcta
     5401 ccgctttttt gaaagcagca agtgcttgtt cactaccgtc gatacctact aaaatattct
     5461 tatattcttg attcatcttg acccctccta acagatgtca gccttttgtt acactttcta
     5521 ggaacgattc gatttcctgt tttgttttac gatctttatt cactagacga cctaattctt
     5581 ttccgtcttg gatcacgaca aaacttggga taccaaaaat gttccattca gcggctacat
     5641 ctatgtactt gtcacggtct acttcaataa attgccaatc agaaaagtca ttttcaattt
     5701 caggcatttg cggtttgata aaacggcagt ctccgcacca gccggcagta aagaaaaata
     5761 cactctttcc agtttctacg tagcctgcta attcttctaa actatttggg ataatcattc
     5821 tttgtcctct actttctgtt tatgtatttt tcaattaaat tatacacctt tctttcgaac
     5881 taacaaacat tgatcctctt tttataaaaa aaatctggca aaaagcaatc ttttgccaga
     5941 ttttatagtt tcactatcgc attattttcc gtatacgatc gtatttactg ttgatttatc
     6001 caaacctttc agtgtttgaa tcaacatttc tcgtgcagct tcaaaatcgc gaatactgaa
     6061 catcgtttga tgcgtatgga tataacgtcc cactacgcca atcactgtac ttgggattcc
     6121 ttcgttttgt gtatgagcag cacctgcatc tgtaccgcct tttgaaacaa agtattgata
     6181 agggatattg tttgtttcag cgatatccag caagtactcg cgcaaacgag gaagcatgat
     6241 caaacctgga tcttggatac gcatcaatgt accttctcct aaatgtccga atgtgccatt
     6301 tttcgtcact gtatcatctg ctgcagagca gtctactgca aagaacagat ctggcttgaa
     6361 tttattgaca gaagctttag aaccacgcaa gcctacttct tcctggacat tcgcgcctgc
     6421 aatcaatgta tgacctaatg tttcattttg caacgcttct aaagcttcta ataccattgt
     6481 acagccatag cggttgtccc atgatttact gataatattc tttccgttgg ctgttttgat
     6541 cgtttcagcg taaggaacga ttgtgtctcc tggaaggaca ccgtaactca ttgcctcttc
     6601 tcttgattca aacccagcat cgaacaaaat atcggttact tctactgatt tttgtccgct
     6661 tgttcctcgc aataaatgtg ggggaacgga agaagaaata catggataat tcttaccagt
     6721 agaggtttta agtgtaaaac gctgagcaga aacaacgtaa ggattccagc cgcctagagg
     6781 tacgacttta aaaagcccgt tttcttggat ttgtgtcagc atgaatccga cttcatccat
     6841 atgtgctgcg accattacac ggggtgcatc cgcttcttca tgatggcgca gaccaaaaat
     6901 gccgcccaaa ccatctaact gtaactcatc taccagcggt tccatatgac tttccatata
     6961 agcgcgaaca tcttgttcaa aaccgcttgt tccttgtaat tctgttaact ctttgattcg
     7021 ttgaaatgtt ttttcttcca tatgctattc gtctaaattt cagactaaac tcctctcaga
     7081 cttatattga tctgcggata aaatatgatt ttttctgcag accgatcgta tttattatag
     7141 cttatttttt ctggtagcgg ttatttattt caaagaaaat atgagagtgt ggtaaaataa
     7201 gcacaaggag taacaagtga gaagaaggag gtatgtccac atgtatgaag aaagcgaact
     7261 aagctatttt aaaggcgggt tagcagttgg aatcggtcta ggattattga gcggggtagc
     7321 ttcaacgatt tggtatcatc gcaaaaaagt attgtcagca gaccaagtac ttgaaaatat
     7381 caagtcatct tttctaaaag aaggtgcaat cgaaggttct tggatctctt ttgaaaagga
     7441 acctattagg aaattcgccg ttcggtcgag tgcttatcgg ggaggtcttt ctcgaataga
     7501 agatggcgaa actgtttatt atgaattttt agcagatgct catacaggaa ccgtattaga
     7561 aatttcaaga aaaaaaggtg caacagatta atacgtcaaa aaagtgagag aacgaatacg
     7621 cacccactat tcaaaagaga ggtatcatgt ccttcttttg tagtgggtgg ttttttagat
     7681 agagctttcc aaacatatat tccagtattt tctttttaaa taaatgatat ttagcgggaa
     7741 aaactagcat ttcctttgat tatgaggtat ttttaattta gcttttgttt tctatagtta
     7801 aggagagtga aaaatggaac aacaagaaaa aattgctgtt ctgattcctt gttacaatga
     7861 ggaagcaaca atttcaacag tcattgcaga ctttaaacga gaattaccag aagcagatat
     7921 ttatgtctat gataataatt cgaccgatcg aacatacgaa ttggccgttc aaggtggagc
     7981 aatcgtaaaa aaagaacctc gtcaaggaaa aggaaatgtg atccgccaaa tgttctttga
     8041 tatcgatgcc gactattatt taatggtaga tggcgatgat acttatcctg cagaagctgt
     8101 acatggtttg ctcgagaaat tacgttctgg tgaagcagat atggtcattg gtgatcgcct
     8161 atcaaatgga acctactttg atgagaataa gagacctttc cacgattttg gaaataacct
     8221 tgttagaaat acaattacta gaatgtataa aacaaaaatt cttgatgtca tgaccggcta
     8281 tcgaggattc aatcgtatct ttgtcaaaag ttttcctatt atgagttctg gttttcaaat
     8341 cgaaacggaa ttgacgatcc atgctttaga taaaaaattc aagttcgttg aaatcccaat
     8401 cgattatcgt gatcgtcctg aaggcagcga atcaaaattg aatacattct ctgacggatt
     8461 caaagtgatc atgatgatta ttaaaatgtt taaagattat aagcctttgc ttttctttgg
     8521 gatttggacc atcttcttct ttttatttgg attggtcacg gggattcctg tgattcgcga
     8581 atatatgctg acaagcttta ttacacgcat cccttctgcg attttaagta ctggattgat
     8641 gactttagca cttctttcat tagtaacagg gttgattttg gatacagtcg tcacgaacgc
     8701 taagaaagaa tatgaattga atctatatca tgtttatcat gaataccaca gtagaaagta
     8761 aaaaaaggat caagactgca aaaataattt gcaattcttg atcctctttt taattaatta
     8821 tttcgccaaa cgatagatgg catctgcata gattgctgtt gctctgaaca agtcatcaag
     8881 actcataaat tcgtttgctt gatgcattgt atcagtatat cctgggaaca tcgctccata
     8941 agcaacgcca cgtttcaaca aacgtccgta agttccgcca ccgatgattt gttcgtagcc
     9001 tttttctcca gtgtggtctt catagacttg caataatgta gccaccaatg gatcatccat
     9061 tggtacgtaa tgtggttcca ttacgcgagc acctcgagta actgttgcgc cttcttgccc
     9121 cactgtttgt tcgatgtcac tttgcaatcc gtctactgtt acaccttttg gaaaacggaa
     9181 attcatattg atgaagttcg cttcctctgt accattttct tcaaaagcaa atagtccagc
     9241 attcattgtc aatttgccca ttttttcatc ttcataagcg actcctagtt tttctccata
     9301 aaaatcttca tggacataag cagctgctac atggataaat tgtttagcag atcctaggaa
     9361 ttcatagtta tctaagaaca atgccaagaa agaacctgca ttgataccag attgtgggct
     9421 tgcaccatgt gcgcctttac caactaattc gatttttaca tacgtattgt ccgcttcaat
     9481 cgttccgctt actggatttg cttcgatgaa ttggtaaaat gcttcttcca tcgcgatagc
     9541 tgcatctgca cttggtactt gaagtgctgc agttgctgtt cctggcacca tattttcgcg
     9601 aagtccggaa acaaaagatt tcaagacata atctcctgca ttgtcgcctt tgaagcgtaa
     9661 agctaaagaa acatttcctt tttcaccatt gatgattggg aattcagcat ctggtgagaa
     9721 accaaaatct ggttcttctt catgttcgaa ataataagcc atatcgcccc agccgctttc
     9781 ttcatcgctg ccgactacga agcgaacttt ttttgatagt ttcaagtcaa gttctttaat
     9841 gatcttcatc gcatagtaag ctgccatact tggacctttg tcatcgcttg atccgcgtgc
     9901 aaagatcttt ccatccttga ttactggttc ataaggatct gtgtcccagc catctcctgc
     9961 aggaacgaca tccatgtgtc caaatatccc tagcgtttcg tctccttcgc caagatcaat
    10021 atgccctgca tagttatcga cattttttac tttaaatcca tcacgttcgc cataagctaa
    10081 catatgtttc aatgcgtcgc gaggtccagg tccaaatggt gcatctggtg ttacttttga
    10141 gtcatcgcgc tcgctgttga cacgtaaaag atttttcaag tcttcaagca agtcttcttt
    10201 acgtgcttct acttcttttt gccaatcaat tgtcataaag ttaatcctcc acttatttaa
    10261 gtcttcgtgt tcatgatacc acaaattaca gaaaaaaata gttcaaaaaa tctgacaatt
    10321 ccttttctta tctgtttttc tctaaaaaaa atatacgcta taatgagtaa aaggaggttt
    10381 ttagatgctg ataaacgaac aactagtgaa aagagtcatc acacctcgtc caaaaatttc
    10441 acataaagga acatttggac gtatcgtttt gattggcggc aatgaacaat atggcggagc
    10501 aatcattatg agtgctttag ctgccgtaca cagcggagcg ggtctcacga ctgtagtaac
    10561 tgatgaaaaa aatcggagtg ctcttcacag tcatctgcca gaagcaatga ttgtagtttg
    10621 gacggatact gaccagtttc tttccgtaat aaagcaagca gatgtactct tgattggtcc
    10681 cggattgggt acttcttcta agagtttgga acgtttcaaa caagtactag aaaaccaatc
    10741 aaaagaacaa tggctggtga ttgatggctc tgctttaagt ttacttgctg ctaatcatct
    10801 tttgctaccc tatcccgaac aaactgtact tacacctcat caaatggagt ggcaacggtt
    10861 gagttctcta ccgatacaag aacaacggga taaagaaaac aaaaagaagc aacaggaaat
    10921 cggtgctgtg ctcgttttga aaagtcatga gacaaaaatt tatggtcacc agcacttcta
    10981 caccaatcct ttaggttctg ctgctatggc aacgggcggc atgggtgaca ctttagctgg
    11041 gatgatcaca ggatttttag cccagtttcc tcaaaatgac caaacgattg cagcagctat
    11101 ttatcttcat agtttcattg gagaccagct ggcaaaagaa caatatattg ttttgccgac
    11161 acaaatcagc gaagcacttc cgaaatggat gaattatttt tgtaaaaaat caatggaaaa
    11221 cgaggcatga gtcatggaga aatttacagg ttatgtgcga gaaccttttt attatgaaac
    11281 agatcaaatg gggattattc atcacagcaa ttatatccgc tggtttgaag aggctcgggt
    11341 agccttattg gtacatctag ggtttcccta taaaaaaatc gaagaatctg ggatcatcat
    11401 ccccgttctg gaagtaaatt gcagctataa agaaatgatc cattacggag aaaaagtgag
    11461 catccatcca actatccaaa agtatacggg gacacggttg gattttagct acgaaattgt
    11521 gggaactgaa gacaaaaaat taaaaactac tggcagtagt aaacactgtt ttttactttc
    11581 tgattcgcaa cgattagtga agctgagcaa agtcaatccg gagttagatc agttattcca
    11641 agcgtacgct tctttggatg atgtaaattc ttaataaaga ccgtctaagc atttttcttg
    11701 tattgtgtcg agtagttcgt ataatgaaaa gaaaaaagca ggtgatcccc atgtatgtcg
    11761 ttaaagtaat gcacggttac atcgataaaa ctggctgtcg cactcgggaa aaaaacttag
    11821 acaatctgct cattttcaaa gacaaaaaag aatccgaagc ttttgctaaa agaatcggcg
    11881 gtcgtgtcaa accgatccaa gaggtacgac cagattgatt caatattttt cttttcgagg
    11941 ctctaatagg catgcctatc agggcttttt ttgcagactg tgtttttatg cccacacgat
    12001 ttgtaagcga tttatgttat aatagattat atctgcatag aaaggaaggt taaatggtta
    12061 tcaataattt gcaacagcaa gcttatgaat ctatacgtaa acaaatcatt tattccgagt
    12121 tagcacctgg aagtaaaatc tccgataaag tgttagaaga acaactagct atcgggcgta
    12181 caccgattca agaagcactg atccaactgc gcaatcaaga gcttgtaaaa accattccac
    12241 agtccggcac ttatgtttca aaaatcgata tccgatctgc ttcattagcc cgttatacgc
    12301 gggaaaagtt ggaaaaaccg atcctgcaag aatgcagtgc gaaaatgacc aagcaagatc
    12361 aagctaaact agaaaaaata ctagaacaaa ccgatcaggc agtaatcgct caaaataaaa
    12421 aagctttttt tgatttggat actgattttc accgaacttg ttatgaaatt gctggaaaac
    12481 gagaaatttg ggattggcta gaaagttata gtacgcactt gaaccgtttc agatggttac
    12541 gtttgacgat ttcagaatta gactggggtc gagtattaga tgaacatcag acaatgcttc
    12601 aatcaatgat tgatcataac tttgatgaag tcggatttct ttgcacgatg catttacata
    12661 tgattatcga ggagcaagaa tacgtgattc ataattaccc cgattatttt gaagatattc
    12721 aggacagacc catcaaataa gaggttttgg aatcagcgtt ttgacctgag tattagagaa
    12781 agaaacggca aaatagttcc tcatattttg ccgttttttt tgagctaata ccgagggtca
    12841 gctgattgca caccgtttat tgagaggttg tgaaaaagct gccctgcatc aagtaataag
    12901 aacagccaag taaaaatagc ttcttatgtt tttaacttgg ctggacttat taccgcagat
    12961 gcaagctttt gaacaccgtt ttccaagagg tcgtgagcct gccgttcatc tccgagtcac
    13021 aaggaacaat ttcaaaaaac agcttctcat gtttgttgaa tattttgact tgtgaccgag
    13081 gagttgacag gagaacatcg tttattcgga aaaaaaggac tgtgacacga cttttgtcac
    13141 agtctcttta tttgtaatct aaatcatact ccgtacatct tttttctatt ttttttattt
    13201 cttctaagat cccttggcta cgaatttcat tatatggcca aagtaagact gcctctaata
    13261 cataaggcga aaaatcgctt tgattcatct cttttgaaaa actcatcgct gctatctcgc
    13321 tcaatgcacg aatgtttgat tgatgtgtat aaaaaggcaa ccgccacagc acaatttttt
    13381 cgctttgcgt ataaattccc ttaacagaag cttcgatgtg gtgaaatagt tcatgtccaa
    13441 taatcaaagc ttgcgctgtt tctttagaga tcgaagctag tcctgaacat tttaattttt
    13501 ctaacggctc cgtcatcaat cgaatccctt catcttctgc ataagttgca aaagtgattc
    13561 gttcgtttat ttgctctgat tcacaggaaa cgattggaac agccatttgt tcacaaattt
    13621 ctcctacatc ggcaaaaggg tacttttttt tgatgctaca tgccgtttcg ataccacaat
    13681 cgattgattg ttgtataaga attttctgct tggacaaagg aatctttttc caaaataaat
    13741 ctcgccgaaa ctggtagaat ccccaaattt cttcggggat ctgttgtaat tcgtttagta
    13801 actcttctaa cttatgtttg tttgatattt ccggcaacga cgatcacttc ttcctccggt
    13861 tccatagtag atacttccag atccatcaaa agctgtagtt gttccagatc cgtcgctgta
    13921 aaatcagaga ctcttgctcc taagcagaga taaaattctg gtcgggcaat caattcagtt
    13981 tgataaactg ccatatcttc ccaaagttgt tcgacagctg tcatataatt ggctgcagtt
    14041 gttttcatac atgaagcatg tccacgttgg accttgataa atcctttttg atcgatgatc
    14101 cgaagacttc cagcattttt tgaacgattc tgttcgccgc atacataaaa gaaaggtgta
    14161 ttttccaata agcaaacttc atttttattt aatcgcatat cctctgcagc aagctctagt
    14221 gcttcttctg ttgtgatctc cttggttaga tcggttgctt tcacttccgt agaaccagta
    14281 gcgatagccg ttacttttga agtctgtgga tcgatttcta cgtggacttc gatcgattct
    14341 ggtgtagcgc ctgattcaat cgctttattc atcgcttcat ttttcaacga tcgtatatct
    14401 tctttacttg gcgaagggat gatacgttct acaacatctc ggaccattgc aagtgctaca
    14461 ccaatagaag aaatcacttc ggcgttttca ggaatcgaat atttcacacc cattttatta
    14521 ctaaagtaag taatcaatga ggcagcgccg ccccctacac ctacaagaga aatctgatct
    14581 ttctccaagt gatacttgtc tgccaattct aaaatcaccg gttcaatctt agcataggat
    14641 ttttccatga tctgttctgc gatgtcttca accgtcgtat gacaataatc agctaatgct
    14701 tggatggctt ttcgtgcaga tgggacattt ccataagaaa aatgttcttc ttgcactaat
    14761 ccaaggacat tggctgcaca tgtatttgta atagtcactt cttctccgtc ttccatcact
    14821 accttgacgt aatcagcagg gtctccttct ttaggagaga aaaattcaac cttaggacct
    14881 ttgatttttt ctgtctccgt aaatactgca taatctagac cggcaatatg tgcagaacgt
    14941 ggaccgacat cgatgattcc tgactgatta gcccgtacca tcgaaccgcc tgccacacct
    15001 agaacccgaa catctaatga agagatatat gttgggtggc cacctacaat tgaataatcg
    15061 attgctggac gtccattttt aatgaccccg atattggttg ttgttccgcc tacttcaaaa
    15121 taaacaccat tagacgctct caagtacatc aaagagccca tgactgatgc tgctggaccg
    15181 gaaagcatgg ttaaaacagg tcgttttttc atttcattga tttccattac tccgccgtct
    15241 ccgcgcataa tcatcaaaga aacattgacc cctgcttctc gtacggaatc ttctgtagag
    15301 gttgccgtat ctagcatttt tggtaaaata gatgcattga ttgctgctgt ccgagttctt
    15361 cttgtcaatc catataattt tgtgatgtca gaagccatcg ttgtagggat cgattttacc
    15421 gatgctgctt cataaacaac tcgttctggt tccccattat ctactccaaa tgccatagaa
    15481 gaaaccaaga cctccgctct ttctctttct aaagaagaaa tcgtttctga aacacggtct
    15541 acatttaagt gtttgacagg taagaatgca ttgacaatct ctattttttt cttattccct
    15601 aaatcgatat cgttcaatct agtttgtcgt tttgctaaaa aaccttctaa tccacctttt
    15661 gccatcccga ttacgccgac ttttgctacg tctccttcaa tcagtgcatt agtcgcttgt
    15721 gtggtagaat gtgcaacaaa cacaacatct tctggactga tattattttc cagcaaacaa
    15781 ttttgaaaag actgaacgac acctgcggct actccacgga catcatcgtg ggttgttttc
    15841 actgaagatt ttccgatgat ttcgtgcgtc gcattatcga ttgcgactgc tttcgtatgt
    15901 gtaccgccaa catcaattcc cattcgcaca aaacgtttca ttttcttttc ctccattcat
    15961 ctaatcgttt ttatcgacgt tttgtttact aggcgttccc gtacaataag aacgtgatca
    16021 ggcataagat cgctccgatg atccaaccag ttgggatgga tttcttcata tattctcgag
    16081 aagttacttt tgtataacct aatccccaag caacccaaga ttgtgtaata tctaaatgct
    16141 gaggagcaat cgttgtgatt gcaaataacg ggaacaaaaa ggctggcgac atcgttggat
    16201 taacagctaa tacgacagct aaaatagctg agcctgaacc gactagattc attggaccgc
    16261 ggaaaaatcc tagtggtgtc aatatagcaa atacgattgc caagactaat ggtgattgcg
    16321 gtatccaatc tccaaaaata gctgaaaaat aaggagaagc atacgcagct gaattattga
    16381 acatcgctaa ggtcatcaag aaaccaacca ttggcgcaac atctactgcg ccatctgtaa
    16441 ataatttcgc aaactgacga cagatttctt tataacctcc gcgcaatttt ccagtaaaca
    16501 gcaatgccca gatacctgct agaataaaac ctaagatgat tggaagatct aaaagaacga
    16561 cccctaaaac tggtaataat acggctaacc atgagatcat tggtgcgtcg ccaccttcag
    16621 ctggtacgtt tgctgccatt gcatagcgtt tctttttgtt cattgatata ttagcgaccg
    16681 ttagtaccac aactaagctt acaatcatcc caatcatacc aatttggaaa tagtcattat
    16741 aagtatagct ttcagccgct ggattgaaac cagcataaat cgtttgatat tgtttgaaat
    16801 tgacgatatt agcaaagatt ccagccataa tcgagcccat aaatgagaac agtgcaaccg
    16861 gtactgaaat acctaatgac atcaagattg gcaacacaat aactgcaata gaaatcactg
    16921 gtccgattcc tgtcatcgac atgaatataa cagcggttac aatacatagt aagctcatcg
    16981 tgattcttgg cttgtcccct ccaagttcaa ctacctttcg aatcagggta gctgcgattc
    17041 cgctatctac tagaacacgc ccgaaaaagg caccaaagaa gacatttacc aagatcgatt
    17101 tggcgtactc agctggcccc gtcgtataga tatgcgtcaa cacatcaatt actccttgcc
    17161 cttccatcgc cgggtttggt gaaaacgtgt ttccgactag cgctaatccc atccatacag
    17221 tagccatgat ggcaaagccg accatcaagt tgtagccttt tacacagtac cagaccatga
    17281 aaaagaatga gataactaac aaaataccaa taataatatc actcatgtta ttcctccgtc
    17341 cattttgttt ttctgataag caaactaata tatcagtcaa actcattcta acttatgtag
    17401 ttagcgcttt cattaaaggg tgaccataaa tgttcagttt tcaattaaaa aaccttaatt
    17461 atgctatttt agacttatac gttattgtcc tgtttcattt gatggaggat tgtaaataaa
    17521 aaaagaggaa agaacataac ttttcgttat cttctttcct ctttataatt gtttagctta
    17581 tttagccaaa gcttcttttg cttggtcagc caatgcagta aatgctgctg catcgttaac
    17641 agccaagtca gctaacattt tacggttgat gtcgatttca gcaactttca aaccgtgcat
    17701 taattttgag tagctcaagc cattcatacg agctgctgcg ttgatacgag caatccacaa
    17761 tttacggaag tcgcgtttct tttgacgacg atcgcgatat gcgtagttgt atgaattcat
    17821 tacttgttct tttgctgttt taaataaagt gtgttttgaa ccgtagtaac cttttgctaa
    17881 ttttagcact cttttacgac gtttacgagt tactgttcca cctttaacac gtgccatgta
    17941 taattcctcc taataaaaat aaatcttcag attctgttat ttgtacttct tatttcattt
    18001 ttgctagttg ttggcgaata cgtttgaagt cgccactaga aaccatgctt gctttacgca
    18061 attgacggcg ttgttttttt gttttgccgt ggaaacggtg acttgtaaac gcgcggaagc
    18121 gtttcaatcc gcctttacca gtacgtttga aacgttttgc tgatccgcgg tgtgtttttt
    18181 gttttggcat gactatattt cctcctcaaa atctttcgtt atccgactat cggctgtcca
    18241 acagccagtt agtcattcaa attacttact gtcgtttttc ggtgccagcg tcaagaacat
    18301 gctgcgtccg tccattttcg ctttttgttc cactgttgca atatccgcag tttcttcagc
    18361 taagcgattc aagacttttt gaccaatttc tttatgggta atggcacggc ctttgaaacg
    18421 gatagaagct ttcactttat cgcccttttc caagaactta cgtgcattac gaagttttgt
    18481 attgaagtca ttcaagtcga tcgtaggact taagcgaact tcttttacat tgatcacttt
    18541 ttgtttttta cgcgcttcgc ggtctttctt ttgttgttcg aaacggtatt taccgtagtc
    18601 catgattcgc gcaactggtg gtttcgcacc aggggcaact aacacaagat ccaagtttgc
    18661 ttgttctgca atattcaatg cttctgcttt tgtcttaact cctaattgct caccatctga
    18721 accgatcaat cgtaactctc gtgcacgaat gccgtcgtta accatcatat cctttgctat
    18781 ggtcattcac ctccaaatat tatgagagaa agaaaagctt accgaataaa cggcaataaa
    18841 aaaacgagtt ctcttacaga acccgcgcgt acttcaccta atagaaccag tgaaaactat
    18901 ctagcccagt gacattatca actaaggcga gaagcgggtg cttctgcttt tatttctcaa
    18961 ccatcatagt atagcaaaaa ctaatctttt tgtcaatgtt tttcatacag tttgtcttcc
    19021 ttttctgaaa atgattagat tagcagactt tcttgcagtg attcccgctt ctttgctata
    19081 ctaaagaaaa acgaggtgaa cccacatgaa aaaaatcgaa cctattccac cttctcttcc
    19141 tcttcttaca aagggagagt tttatttaga agatgaggag atcttctctg gtcttctgat
    19201 caacgggggt gaccaaagct atctcgatgc caaaaatatg gtattaagag agagtcatat
    19261 ccaaaaactt acgatgcaaa aaacagtttt acgtcatttt gaatgcagta atgtcatttt
    19321 tgaaaaatgt gatttttcca atctggagtg gattggtggc agtttccacc aagtcgtgtt
    19381 tcatcaatgt aaattaacag gtacgaattt tgccgaaagt tatcttcgag actgtacttt
    19441 cactgattgt attgcttcga tggcttcctt tagtagtaca aacttgaaag ctgtctcctt
    19501 cgatcattgt caattagaag acagcgaatt ttatgaggtc acttggaaaa accttttttt
    19561 gtctgacaat cagttgaccg gttcgaactg gtttcgaact tctctgaagg gattagactt
    19621 tacgactaat ttcttcacag caatcgcttt atctcaagat tctttggcgg gactaatcgt
    19681 caaccaagag caagcacttg tgatcgccca agcccttggt ttgcagatca aagactagat
    19741 caacgaatcc gccgccacag tgcaataagc atccaaatag ataagaccaa actgatgatc
    19801 aaggcgattc cccatccgaa aacggaatgg gtaaagggta actggagatt cattccgaag
    19861 aatcctgtca caatagttgg aacggtcaag atcagcgacc agaccgtcaa aaatttcatc
    19921 gtgtcattca agttgttatt cagcaaatta ttataagtgc cagagagctg gtctaaaatc
    19981 tgcgaagcta agttcgtcat ttcaactgct tgtcgtgctt cgatcagcgc atcgtccaac
    20041 tcttcttttt ccttttctga caacttgcga taaatagcca atgccttgat ttgttctaaa
    20101 agtactacat tttgttttgt tcctgtaact aagtaaacca aaccgatctc taaatctgaa
    20161 agttgcagca gattcttgtt cgttgttttt tctcttaatt tcagattaag ccgctgacgt
    20221 tcactattca cttcctcgat taaaggaaaa aaggaatcag aaatcaaaaa caatgtacga
    20281 aacaataaac tgtatacact catgtctggc attcgttcca aaagcgatcg aattagtcga
    20341 atcacgtact cggtattcgg cgtggtaaat gtaaacaaac cgtcttcttt taaaataaaa
    20401 gcgataggac tagtttcata atgattatcg actttttgct ggtgcggaac atttgataca
    20461 agcagtaacg cttcatcaaa agaatcgtac tctacgcgcg cccgttcatt tttatctaga
    20521 gaataagtca gcatctcgtc actaatgcca tattcttctt ttaagttttt aacagctagc
    20581 acatcgtttt gctgtacatt gatccaaaaa ttacggtctt gattaaaata gtgtttttcc
    20641 cgcatactct atcctcctga catttgtttc cagtataaag aaaaaagtcg ctcaaataaa
    20701 ggtttaccct ttatttgagc aactgtaaat caaatggcta ctttggtttg gcgaatctct
    20761 gctaattttt cttcgatcat tttcaagact tcttcttttg cttgaggatc ttccacaaaa
    20821 ttatagcggt ctccatcgat ttggattttt ggactttctt tgtattcttc ataccattga
    20881 tcgtaacgtc tgttcaattc tttgtaataa tcgtatagac ttggatcaaa ggacaattgt
    20941 tcatacgaac gaccacgttt ttcgatacgc tccaacatcg tatcaaaaga tacacgaata
    21001 tgaactaata aatccggatg ttttttatgg gcagcatagg gaagttcttc catcatgttt
    21061 tccagcagtt catcatacac acgaacttct gtttctgttg ctcttcctag atctgcattt
    21121 agatggaaaa gcagtgaatc ttcataaatc gaacggtcca atacattatt gtcatctttc
    21181 attgcttgtt tgatgcttgc aaaacgttta ttcaaaaaat aaatttgcag caaaaaagca
    21241 tactgttcag ggtttgcata aaataagggc aagacttcat tatcatcaat cgattcataa
    21301 aatgcctgac tatcaaagtg ttcagccatc atttctgtta aacttgattt tccggcacca
    21361 attgtacctg ctaaaacgat cacgctcatt tacctccagc tcacttcatc actaaatatt
    21421 gtgtttaact ccaacctttt taaatatacc cccaatatct agtagtgtca attgtatttt
    21481 tttctagtca aagaagaaaa aaagtcaaaa aattcttaag aaaaaagtgt tttttcttta
    21541 gaaaacgtat tcttagtttt acttctgaga tggttttagt aaaataaagg aggaatgttt
    21601 tttgagaccc ttagtggaca aaaaaattcg tgaagcagcg caactcgttt tgggcgcttt
    21661 attttttgct taaaaatcac ttttacgtga gaaggagtta gattatggca aactatggcc
    21721 aaggagaatc aagcggaaag atcatattga tgggcgagca cgcggttgtt tatggagaac
    21781 cagcgattgc ctttcctttc tatgcaacaa aagtcaccgc attccttgaa gagctggatg
    21841 caatggacga tcaactggtt tcttcctact attcaggaaa tttagccgaa gctcctcatg
    21901 cattaaaaaa tatcaaaaaa ttattcattc acttaaaaaa acagcatgac atccaaaaaa
    21961 acttgcaact gaccattgaa agcacgattc ctgctgaacg tggaatggga tcaagcgctg
    22021 cagtcgccac agcagtcact cgtgcttttt atgattactt agcatttcct ttgtctcgtg
    22081 aaatactatt agaaaatgtc cagctttcgg aaaaaatcgc ccatggtaat cctagtggaa
    22141 tcgatgcagc cgctactagc agcttgcagc cgatttattt tacaaaaggg catcctttcg
    22201 actacttttc tttgaacatc gatgcttttt tgattgtcgc tgatacagga atcaaaggac
    22261 aaacaagaga agccgtcaaa gatgtcgctc acctctttga aacccagcct catgaaactg
    22321 gacaaatgat ccaaaaatta ggatacttga cgaagcaagc aaaacaagca atcattgaaa
    22381 attcaccaga aacgttggca cagacaatgg atgaatcaca atcacttctg gaaaagctga
    22441 caatcagcaa tgattttctt aatctattga tccaaacagc aaaagatacc ggggcattgg
    22501 gtgccaaatt aactggcggt ggacgcggtg gctgtatgat tgcattagca caaacaaaaa
    22561 caaaagccca agaaatcagt caagcacttg aagatgcggg tgctgctgaa acttggatac
    22621 aaggattagg agtacatacc tatgtttaaa ggcaaagcac gcgcatatac caacattgct
    22681 ctaatcaaat attggggtaa gaaaaatgaa gaactcatcc ttccaatgaa caacagcctt
    22741 tcgttaacat tggatgcatt ttatacagag acagaagtca tcttttctga tagctatatg
    22801 gtagatgaat tttatctaga tggcaccttg caagacgaaa aagcaacaaa aaaagtcagt
    22861 cagtttcttg acctttttcg taaagaagcc ggcctctcac taaaagcttc agtaatcagt
    22921 cagaatttcg ttcctaccgc agctggatta gcctcctctg ccagcgggct agctgcttta
    22981 gcaggcgctt gcaatactgc tcttaagctt ggattagatg atctctctct ttcaagattt
    23041 gctcgacgcg ggtctggttc agcttgccga agtattttcg gtggtttcgt cgaatgggaa
    23101 aaaggccatg acgacttaag ttcttacgct aagccagtcc cttccgattc tttcgaagac
    23161 gatttagcaa tggttttcgt tttgatcaac gaccagaaaa aagaagtgtc cagcagaaat
    23221 gggatgcgtc ggacagtcga aacatccagt ttttatcaag gctggttaga ttccgttgaa
    23281 ggggatctat atcaattgaa acaagcaatc aaaacaaaag atttccaact tctcggagaa
    23341 acgatggaaa gaaacggact aaaaatgcat ggaacgactt tagctgccca gcctccattc
    23401 acttactggt ctcctgacag cttaaaagcg atggatgcgg tgcgacaatt gagaaagcaa
    23461 ggcattccat gctactttac gatggatgct ggccctaatg tcaaagtttt agtggaaaac
    23521 agccatttat ctgaggtaca agaaacattt accaaattat ttagcaaaga acaagtaatt
    23581 actgcacatg ctggtccagg aattgcgatt attgaataaa gggagatttt tatgattgaa
    23641 gtatctgcac caggcaaact ctatattgcc ggagaatatg cagttgttga aacaggccat
    23701 ccagcagtta tcgctgcagt cgatcaattc gtgacagtca ctgtagaatc tgcacgaaaa
    23761 gtcggaagta tccaatctgc acaatatagt gggatgcctg tacgttggac aagacgcaac
    23821 ggagaattag ttttagatat tcgggaaaat ccttttcatt atatccttgc tgctattcgc
    23881 ttgactgaaa agtatgcaca agaaaaaaac attcttttat ccttttatga tctgaaagta
    23941 acaagtgagt tagacagttc aaatggccgg aaatatggat tgggttctag cggtgccgtg
    24001 accgttgcaa cggtcaaagc cttgaatgtt ttttacgcgt tgaatttatc tcagttggag
    24061 attttcaaga ttgcagcact agccaattta gcagttcaag ataatggttc ctgcggcgac
    24121 atcgctgcta gctgttatgg tggctggatc gctttctcaa ccttcgacca tccttggctc
    24181 caagaacaag aaactcagca ttctatcagt gagttacttg ccctggattg gccaggtcta
    24241 tccattgagc cattgattgc tcctgaagat ttacgtttat tgattggttg gacgggtagc
    24301 cctgcctcta cttctgattt ggtcgatcaa gttcaccgtt cgagagaaga taaaatggtg
    24361 gcttatcagc ttttcttaaa aaatagtaca gaatgtgtca acgaaatgat caaagggttt
    24421 aaagaaaata atgtaacgtt gatccaacag atgattcgaa aaaaccgaca attactgcat
    24481 gatttatctg caatcactgg ggtcgtcatc gaaacgcctg ctttgaacaa attgtgtaat
    24541 ttagctgaac agtatgaagg agccgcaaaa tcttctggtg caggtggggg cgattgcgga
    24601 atcgtaattg ttgaccagaa atctggcatt cttcctttaa tgagtgcatg ggaaaaagca
    24661 gaaatcactc cactgccgtt acatgtctat agcgatcaaa gaaaggaaaa ccgatgaatc
    24721 gaaaagacga acatgtttca ctagctaaag cctttcatga taaacaaaaa aacgaatttg
    24781 acttcgtacg gatcatccat aaccctttgc cgcaaatagc agtttctgat gtcgatctaa
    24841 gtacacaggc agttgggttt acactaagca gcccatttta tatcaatgcg atgactggcg
    24901 gaagcgaaaa aacaaaaaaa atcaaccaag atcttgcaat cgtcgcaaga gaagcagatt
    24961 tgatgattgc cactggttca gtcagcgctg ccttgaaagt cccttcttta gccgatactt
    25021 atacgattat gcgacaagaa tatcctcacg ggaaaatcat tgccaacatc ggtgcaggga
    25081 cttctgtcga aagagccaaa gaagctatcc gattgtttca cgcagatgcc ttacagattc
    25141 atttgaatgc acctcaagag ttggttatgc ctgagggaga ccgtgatttt accaattgga
    25201 aagtacttat tcaagaaact caaacagcca ttgacgtccc cctcatcgta aaagaagtcg
    25261 gttttggcat gacaagagaa acgctcaatg atctagctgc tttaggagtt catacagttg
    25321 atatcagcgg tcgaagcgga acaagcttca cccagatcga aaacgcccgt cgctccaagc
    25381 gggaactgag ttatttagct gactgggggc aatcgacagt ctcttcattg cttgaagcaa
    25441 atgaagcaga cacttctatg gaaatcctag cctccggagg tatccgcaat gcctatgaca
    25501 tatttaaagc cctttgtctc ggcgcaaatg ccgtgggtac ttcaggaacc gtactgacgc
    25561 atctgatgaa tcacggcgta gaagaaacta ttatactgat gaagcaatgg caagaagagc
    25621 ttcgtctgct ttatactatg gtcggcgcaa cgaataccgc ggccctacac caacaatctc
    25681 tgatcttttc cggaccagtg aaggattggt gcgaagcaag agggatcgac ttagtgaagt
    25741 atggaagacg cacagaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc
    25801 taaacacgta caaacggcgg aagtaaaagc aactccttcg gaaataagct aaaattcaca
    25861 aaaatttgaa aagcaatttt cgtgaattcc ttcttatttc ttggagttaa atgcttctgt
    25921 cccagcctct tttttcgaat aaatgatgtt taatcagctg tccttcggta ttcgttcaat
    25981 ccgctgattt cacaacctct ccactaaaca gtgtactaaa gctcttttaa ggttgttttc
    26041 cgatataggc aagtatgcct ccgtccacat acaagacatg gccgttaacg aaatcagatg
    26101 cgctagaagc caagaagaca gatggtccag ccaaatcgat tggctcgccc cagcgtgctg
    26161 ctggcgtacg tccaacgata aattgatcga atggatgacg ttcaccgttt tcttgtgttt
    26221 cgcgtaatgg agcagtttgc ggtgtagcaa tataacctgg tccaattcca ttacattgga
    26281 tattgtattg accgtattca gaagcgatgt ttttcgtcag catttttaat ccgccttttg
    26341 ccgcagcata agcactgacc gtttcgcgtc ctaattcact catcatggag cagatattga
    26401 tgattttacc gccgcctttt tcgatcatat ccggaataac tgcttttgaa acgatgaatg
    26461 gggcatttaa atccacgtcg attacttggc ggaagtctgc cgcatccatt tcgatcatcg
    26521 gtgtccgttt gatgatccct gcattgttga ctagaatatc aactgaacct acatcttctt
    26581 tgatctgttg aaccatcgct tgaaccgctt cttcatcggt cacatcgcag acataacctt
    26641 ttgcatcgat gcctgcttct ttataatgcg ctataccttc atcaactgat tcttgattca
    26701 agttattaaa tacgattttt gctcctgctg tagctaaaga gcgtgcaatc tcaaatccaa
    26761 taccatagac agcaccggtg actaatgcta cttttccatc taaacgaaac atatccatac
    26821 taaattccat cattttctct cccttatgct tattttaatt gatccatttg caccatatcc
    26881 atgtctgtat aggtgatatt ttctccgcac attgcccaga tgaatgagta attgcttgta
    26941 cctacacctg aatggatcga ccagcttggc gaaataatgg cttgttcatt gtctacaact
    27001 aaatgttttg tttcatctgg tttgcccatc atgtggaaca cacgtgtatc ttcattggca
    27061 taatcaaagt agacataagc ttccatacga cgttcatgtg tatgacaagg catcgtattc
    27121 caagcgcttc ctggttctaa aatcgtataa cccatttgta attgacagct ttcgcataca
    27181 tttggatgga tgtattggta gattttacgt tcattcagtg tcaggccttc accagtctcc
    27241 attggtttta cttggtcgat actgattttt acatttggat atttatgatg agctggaaca
    27301 gaactaatat agaatttagc tgggttttca gcatcttgag aagaaaatac aacatgtcgt
    27361 gtttcttttc cgatatagta tccgtcttgt tttttcattt cttctttttg cccatcgatc
    27421 tcgatgaatc ctggtccacc gatattgatc acacctagtt cacgacgctc taagaagtaa
    27481 tcaacaccta gttctttgtc taatgtgatt tctaattctt tttcagtagg tgtcactcca
    27541 ccaaagatca ttcgatcgtt gtgcgtataa gtcaaactga ttttccctgg ttcaaatacc
    27601 ttttctacta aaaattcttt tctcaattgt tccgttgaat aatgacggat atcttctgga
    27661 ctgtgtgtat aacgtgtttc catttcttgc attttcttct actccttcta tcgaatgatt
    27721 tttccagagc cgcatgctaa aaattgtgcg acttcttctt gactaaattg gttgcagtcc
    27781 ccatggatcg tatgcttcaa ggcagaagct gccgtagcaa aatcaatgat ttcttgcgga
    27841 gacatattgg ataaaatccc atggagcacg ccacctgcaa aagcatctcc gccacctact
    27901 cgatccacga ttggggtgat tctatggact tgggattcca catattcatg gttcatccac
    27961 aatgtcccct tcaattcatt ttcacttgct gaatgaacgg tacgcttggt cgaataaaac
    28021 acctgaatat tcgggaactt ttcctgcatt ttttgataat aataaattag aggttgttct
    28081 tctgcttctg gcgctttctc gatacctaac aaataaagag catccatttt tccagctgag
    28141 cagatatcta ctaaaggtaa aagctgatgg attacttcgc tggcttcttg ctgtgtccat
    28201 aattttccac gatagttgat atcgaagctg atcaggcagc cagctttttt tgcagcttct
    28261 atcacctgtt tcgtcatttt ttgccatttt ttagacaaag ctggggtgat tcctgaaaca
    28321 tgaaatatat ctattccttg gaataactcc tctagcgacc attccaaatg atccatttca
    28381 gcaaaacttg atccggcacg atcatagatc actgaggcgg cgcgttcgcc actaccagtt
    28441 tccatataat aagtacctag tcttgatcca ccagataata cctgtttcgt atctactcca
    28501 taacattgca agtgcttttt gactgctttt cccaatgcgt tatcaggtac ttttgtagca
    28561 aaaatcgctt catgtccgta attagctaaa gaaattgcta cgtttgcttc ccctccgcca
    28621 taatgggcag cgaatcgttc acttgaatcg atacgggttc cctgctctgt ggacaatcgc
    28681 aacatgattt ctccgagtgt cactactttt cccataagca gctacctctt gatttctttc
    28741 atttttgctg catactgttg cgcgacttcc gttactttgt caaaatctcc tgtagctgcg
    28801 ggtgctaaaa ggttcccacc tactccgact gttacgacac cagcatcgaa ccactctttc
    28861 atattgtcca gactcacacc gccagttggc atgatattga cttgaggcat cggcgccttg
    28921 aaggcagaaa tgatacttgg tccataagcg cttccaggaa atagtttgac gatatctacc
    28981 ccgcttttca gcgctgtttt gatctcggta atagtcatac atcctggtaa gtaaggaatt
    29041 tgatacagat tgcacatctc tgccgtttct tgatcaaagg aagggctaac aatatactct
    29101 gcgccagcta agatagccaa gcgagctgtg acagcgtcta atactgtgcc tgcgccaatc
    29161 actatttctg gttggtcttt gtagaatgac aaaagttctt tgattacttg atctgcttga
    29221 gggactgtaa aagtcaactc aataccagtt agaccacctt tgatgattgc gtggcaagca
    29281 ttcaaagctt cttctttgct ttttccgcgt accaccgcaa tcactccggc gtttttcaat
    29341 cgagataaaa tatcaatttt tttcatcttc tccacctatt tcctatttag aaattttatt
    29401 ttataacttg gaaatctata cccatattat acggcagaaa agaaaaattg caaacgcttt
    29461 tttcattatt tttgaattct ttgctcgatt tcgctttttg tttgcttgag ggcactgatt
    29521 atttgttctt ttgtctcatc tgttaaacga tatttcggca tacttacact aaatgcacca
    29581 atgatttgtt cgtttttcac gattgaggct cctatacaaa aaatatcacg ttcgatttct
    29641 tcatcgtcaa atgcgatgtg ggtttctttt accgttttga tttccttttt caaccgtaat
    29701 gcattggtga tcgtatattc tgtgtaaggg atcaacggat gcttttcaag ataatcagtg
    29761 tactgctctt cactgaattc tgctaatacg gctttgccca tcgcagaatt gtataatggt
    29821 cgggtgattc cgatttttga agacatgcgg atcgtttgat gttttggatc tagtttgttc
    29881 acgtacaaga tctcattgtt gtccaatacc cctaagtgga tagtctcatc gatcttttgc
    29941 tgcagctgtt ctaaaaacgg taaagtcaac tctaccaaat cgatttgttc aatgttttta
    30001 ttcgcgtagc gaataagctt tgcacctaaa cgatagtttt tctctgaatt tttatttacg
    30061 tagccgatca tcaacaaagt atctagtatt ttcaagactg tagaagaggt cattcccaca
    30121 ccctttgcga tcgtctgcaa agagacatct tggttttccg ctaaatagtc tagtatttta
    30181 gaggctttga tcaatacagt tccataaggc tttttatttt ccatataata ttctcctatt
    30241 tctttataag aaaaattata gcggaaatac catcaattta aaagagatat ccagatataa
    30301 actaccattt ctctttacag gcaatttaat gttgaagatc cgcttcgttt ttacatcaaa
    30361 ctttgatata aagcaatgat ttcttctact gtcgtttctc ttggatttcc tggtgtgcat
    30421 acatctcgca aagcatcttc tgcaattgct ggaatatctg cttcttttac acctaattca
    30481 gaaatggttt ctgggattcc aaccgctttg ctcaaccgat cgatctcacc acaagccgct
    30541 tctcttacat cttctaaaga catttcagct gctcctttaa tccctagaac aagagcgatc
    30601 tcacggtact tttctccagt atattctttg ttatatttca tgacagttgg caaaagtgct
    30661 gcacacgcta cgccatgagg aatgttgtac catgcactta acgggtgagc catcccgtgt
    30721 accagtccta aaccgacatt tgagaagccc attcccgcaa tatactgtcc taatgccatt
    30781 ttttctcgcc cattttgatc gccatctaca gaagcttcca aagaatggcc gatgatttcg
    30841 attgctttta aatgcagcat atcagtcatt tcccaagcgc cttttgtgat aaacccttca
    30901 atagcatgcg tcatagcatc catacctgtt gatgcagcca attttttcgg cattcccatc
    30961 atcatatcgc tgtcgatgaa cgcgacgatt gggatatcat gaggatcaac acaaacaaat
    31021 tttcggtgat ttacttcatc tgtgatgacg tagttgatcg ttacttctgc tgctgttcca
    31081 gaagtcgttg gtatagctaa tataggtaaa catggatttt tcgtatcagc aacaccttct
    31141 aaactaatga cgtctgaaaa ctctggattc gtcaaaataa tcccaatggc ttttgccgta
    31201 tcgattggcg aacctccacc gattgcgatc aaacagtctg cctctgcctc tttaacaaaa
    31261 gccactccat cttttacatt ttggatcgtt ggattaggta cgatcccgtc gtataaagca
    31321 taagcgattg ctgctttatc tagaagttct gttacttttg ttgctatacc gtgctcgatc
    31381 aatcctttgt cagtaatgac agctgctttg ccgaatcctc gctgctgaaa ttcagggacg
    31441 atcgactcaa tcgctccttt tccaaaatac gatgtttcat ttaaaatcat tcgattactc
    31501 attttctatt cctcctaatt tgtattattt ttcacaataa aaacgaaaga accccaagca
    31561 accggttgcc cagttgcttg ttgctacagt tcaaagactg gcatcaattc ccaactgact
    31621 ggagaggcat ctggatttgt ctccatgata tcttccatgt acttccacca tttttgattg
    31681 atagatgtat ttgccatttt ttcccataac ttttcatctt cgatcactaa gtaaccaaat
    31741 aacaaacttg tactcggatc aagatagatc gaatagtcga tgaccccgtg ttcacgaagt
    31801 gctgtacgca tttctggcca aagttcatca tgtctttttt tgtattcttc ttgtttttct
    31861 gggtaaactt tcatgcaaaa agcttttttc accatgtcag acacctgctt tcgtatgaac
    31921 ttcctccaaa taacctgctt ttggagtgac accaaacgca tctgctaaat gccacaggtt
    31981 ttcgtccgtg attgtttgca agattggtcc ttgcgctttg acgtacgtat agacttctgc
    32041 tgccttttct gctgtctcga tcaaaccaaa gacttcatcc atgtcttttc ctgacccgta
    32101 gattccatgt tgtggccata aaaccaatcg agtttctttc attttttcag ctgttgcttc
    32161 cccaatctca tttgttcccg gaaccatcca cggaatgatg gaaattcctt ctggaaaaac
    32221 aactaagcat tccgtacaca tttgccatag cgtacgacta aaggaacgtt cgtctaattc
    32281 atgcgtaaaa ctcatcgcta atagatgact agcatggcaa tgcataacga tccgattatc
    32341 tgggtctact tctaaacggg cgatatgact catgaaatga cttggcaact cgcttgtagg
    32401 aaggcattcg ttttccagcc cccacaaaag ttccagtgtt ttgccatctt cagcaactcg
    32461 aacgattcca agattctcgg caggttcgct cgctacattt ttaaaatatc ttcctgaacc
    32521 agttacaata aaatagcatc ctgctaaacg gctggcatca aaaatcatcg agatgcggcg
    32581 gatcactttt tcaggatcca agaacggtgt gatctcttct tcttttagta aataagaaat
    32641 attcccgcca tttctttcat cccatcccaa gcgataaaga ttcgacgtcg tttcgatcat
    32701 ttctttcaca taaggcgctt gtaaaatatc tatttttttc aatatagcca cactcctatt
    32761 ttcttaattc caacacgtct ttttgatatt cctggacttc ttccagccaa tccaaaccaa
    32821 ctggaacttg atttttgtaa cagaaataat tccatacatc ggcatacggg aaatctttca
    32881 attcttccgt ataagccatt cttgaagtaa agtcaaaagc cagctccatt tctttcaatc
    32941 gctcaactgg ttccagcata gctttcagca gtgctttttg tgtatttctc gtaccgatga
    33001 cccaagcagc gatacggttg atcgttgcat caaagaaatc cagaccgata tttgtttttt
    33061 ccaacaattc gttacggact aattctttag cgatttcctg caattcatca tccatcaaaa
    33121 ccacatggtc tgaatcccaa cgcactggac gggaaacatg caacatgatt cctttgctga
    33181 ataaagctaa tgaagataat ttattggaaa tcacttctgt tggatgaaaa tgtccagcat
    33241 ctagacaaac aagtttgtca cgagtcaacc cgtaacccat ataaaattca tgggaaccga
    33301 ctgtataagc ttcagcgcct aaaccaaata gtttgctttc tactgcatct tgtacatacc
    33361 gttcatctaa ctcttctgta aaaatttcat cgagtgattc cattaaacgt tcccgtgggg
    33421 taaaacgatc aatcggatta tctttcatcc catcaggtac ccaaaagtta ttgatacttg
    33481 tttgcccagt ttctttccca aagtactccg cgattttgcg gcttcttttc ccgtgttcga
    33541 tccagtattc acgaacttct ttatctggat gagccaatgt aaagccgtct ttcatcattg
    33601 gatgcgaaaa gaaagtcgga ttgaagtcaa gaccgatttc ttcttttttt gcccactcta
    33661 cccatttttc aaaatgtttc ggctcaattt catttagatc gacagattct tctgtatcca
    33721 aatagatagc atgaaggttc aatttgtgtt tgcccggtat caacgaataa gccttctcca
    33781 gatcttgtct aagctcttca ggtgttcgtg cggctcctgg aaaattccct gtcgccatga
    33841 ttccaccggt caattcgcca tccggtgtca agaaaccttt gacatcatct ccttgccagc
    33901 aatgcataga aattttgatg tcctgtatct tttctagtac agcatctgta tctacaccga
    33961 tagttgcata tttttctttt gcttgttcgt aatttctttc aatcgtgttc atacgattac
    34021 tcctttgatt ttattcacgt accattccat cgtgttttgc ttattttcat ctgggtaaaa
    34081 agtttcacat ggaaacgact gtttgattac atttcttgct tgttctatat tcgaaaactg
    34141 acctgtactg agcatttgca tggcaacatt cccgattgct gtggcttcac taggtcctgc
    34201 ttctacaatg attccggcat aatctgctgt caattgattc agtagacgat tattcgatcc
    34261 gccccctacg atgtgcagct tttccaattt cgttccagtt aagtgttcta ctttgatcag
    34321 ctcttgtgcg taacaaagag caagattatc atacacacaa cgagcgatag ctcccgatga
    34381 gacagggact ggctgctctg tttcaaaaca gtattgctga atctcttcta tcatatttgg
    34441 gggattcaaa aatcgagggt cattgatttc catcacttgc tgcagcggtt tttcttttgc
    34501 agcaagctct gccaattccg cataactgta ctcgtactct tgcattcggg caacttcctg
    34561 gatcaaccac atccccatga tgtttttcaa aaaacgcacc gtgttatggg caccccattc
    34621 attcgtataa ttttcagaaa aagcattgcg agaaacattg gcgatctttg tttcaatccc
    34681 taaaagcgac catgtcccac tgctgatata accccaacgt tctccttgac ctggcgttcc
    34741 taatacagct gacgccgtat catgacttgc tactgtgata aaggtcacat ctggcaaatc
    34801 atattttgaa aattgttctt tttgcagatc tcctagtatc gttcccggct ctgtcaatgg
    34861 tggaaataat tccttcgaga caccgatttt ttcaagaagt tctatttccc attcttttgt
    34921 ccctgcattc agcagctgca tagtagatgc attagttttc tccgtcacca tgttaccagt
    34981 aaagacatac cctaaataat caggtatcag taacaattta tgtgcttttg ccaaattttc
    35041 tttttcttca gcaaacaatt ggaacaaggt attgaaaggc tggatctgaa tccctgtctg
    35101 ctcatacaac ttatctagag aatagatttc agaaaactgt tctactgctc cattggtacg
    35161 cttgtcccga taagcaatcg gatcatttat ccgatcccct tgttcatcaa tcagacagta
    35221 atcgactgcc catgtatcga tccccgcaaa aaggcgatca atccctgtct gctttaattt
    35281 ttcaaatcca atcaaaatct ctttgataag ataatcgatc ttccagcgat cgtgaccgtc
    35341 tttgttccga aagccgtttt tgaaccggtg tacttcttcc aagatcaaag aaccttttgc
    35401 atccctcgta cttttcatta gtcgtccgct tgatgcaccg atatcgatgg caacaaatgt
    35461 tggattcatt tctccacctc ttttacttta ttgttgatta gcactttatt aataaagcgt
    35521 tatcatttat tgacaatgct atcataatac agaatcttat attttgcttc acactatttt
    35581 ggtatataat tgcattatct tgacaagttg ggagtgttta catggattac tgggaaaaag
    35641 ccaaccactc atggtcggaa gactcaaaaa gagtgatctt gacgcctaca caaagaagca
    35701 ggaatttatt tttttatatc caagaaatcg gttacttcaa agcaccaatc ccttactata
    35761 ctgaacgagc acatttacct tcttacttga taaagtttac tttgtctggc aaaggttcgc
    35821 ttacatataa tgataatcag caacagctaa aagctggaga cttatttttt attgactgcc
    35881 aagaatatca gcgttatcaa acgatcagcg aagaaccatg ggaaatggat tggatccatt
    35941 tgaatggtca gaacgtccaa tcattttatc aggagttcac aaaagacggc cataacacct
    36001 tccattcaac aggagatcca tcagaaaaca agatccacca tttgatcaca gaattgatcc
    36061 acatgcaaca aggcacgaat gcccgtaccg atttccagtc ctctgtagct atccacgagt
    36121 tgctgaatga actgattttg caaaagtatc agctagattt cgaagaagag gatattcccg
    36181 cctacgttta caaactgaag caatacttag acgaacattt caaagaaacg attacacttg
    36241 atcaattaga acaacaattc ttattgaata aatatcagct gagcaaagat ttttccaaat
    36301 ttatcggttc tccaccaatc gattatttga tcagcaaaaa actttcttac gctaaagacc
    36361 ttcttcggta tacagaattt acggttcgaa tgatttccga agaaataggg attgagaatt
    36421 ttgcttactt tagccgcctg ttcaaagcaa aaacaggact atcgccgaga gactttcgta
    36481 aattcagctg attcatataa tatgtacgtc attttttcaa aatattttga aatatataga
    36541 taaaaataaa ataaccgcag tttctgcttc tatgtaaaca acagcagcta ctgcggttat
    36601 tttttagtga tcattctcat tgttcatctt caaaatgttc ataatgaacc aactgtttct
    36661 gtgtatcacg tttcaaaaat tctttaggcg ttatgccgaa ctctctcttg aatgctttca
    36721 gaaaatgcgg ataagaagaa aaaccacttt tactatatac agcactagag ctgcggtatt
    36781 ctcgcaacaa gtgcttggca tagatcagct ttttcttcat tacatactga tgaaacgtaa
    36841 atccagtgta ctttttaaat tctcgtgtga tatggtattt gctgacaaaa aactgctttt
    36901 ccatttcctc taaagaaagc ggatgagata aattttttga gatatattgt aacatttgtt
    36961 ccacacgctc attaggaact acagcattct gttcttgcgc actctcttct ttttgtacaa
    37021 cttgattgag aaaaatcaag tattctacca gagcttgttc atattttatg tcttcaccgt
    37081 aaattttttt atcaggagga tggtcgataa atgataattt ttgcttcaat acttcctgtt
    37141 ctatttgcaa tacacgactc ctcttctctc ccattggttg aaaacaagcc gatagattag
    37201 accatggcgt ggaacgactt tctagaaaag aaggggtgac aaagatatag acacgctcga
    37261 atacatctga agattggcgg acgatacgat gcaaatcatt ggaatggatg agcagcacac
    37321 ttcctgcttt gatcgtaaat tgtcgtccgt tcaaataaaa agtcgcttct ccctttaatg
    37381 tagcatggat ctcatagaaa tcatgatgat gatagatcgt tttattttgg ctgacgacat
    37441 ctttgacatg atagatttca tactgatcag aaaccatcgt attgacttgt tcaccgctga
    37501 ttttcttttg gagcatgtgc cgcacctcct tttgttcact tatgcacaat tttattatac
    37561 cacgtttttt gtaatcaaaa agagctgctt ttatatactc ttataaaaaa gaagagacgt
    37621 ggcatcttct agccccgccc cctccattct aaatattagt taaccaacgt cttctttaca
    37681 ttattcaaga agacttcttc cataacgaat cccatcatct tttgtttctt caagaaccac
    37741 atacaggtac ggacgattct tcatgatgat ttctttgatt tttgtgtact cgatcacacc
    37801 gtctcccaaa tttaccggca cgattttttc ctgttcgaca cgaaaatctt tcaaatgaac
    37861 cgcacatatc ttttcaccaa aacgttcaaa agcttcttct accaattgga cttgttcttg
    37921 ataatcacta cttgtgatca aattggtcgg atctaaaatg attcctagat agtccgaatc
    37981 tactgcttgg atcagctgct ctacccttgc taaagaatac accggatgat tcaaacctgg
    38041 ttctatcccc accatcattt ggtatttttc tccagctttt accaagcgac ggataacgga
    38101 cacagcttca gcaaatgctt catctgtgaa attttcttcc gtatattgga tttccggcaa
    38161 aacacatcca gtttccgaag caaccatcga cgcaccaaag gaagaagcat agcgaagata
    38221 ctgctcgaac tttgtcagca actcttgtcg tatcgttaaa tctggatgaa tcatattgat
    38281 atagcaactt aaaattccta cggtcacttc ttgcttttct aaaactcgtt tgacataatt
    38341 tcccatccca gaattgatct catttgcgcc agaaggtatt tcaggaaacg aaagacctaa
    38401 ggcgagctgc agtgtatgaa tcccttgttc ttttgttttt tctgcaagat cttctatcgt
    38461 ttggacttcg gaaagatcat gtcctctaat tgtaatgttc aacataacta ttctcctaac
    38521 tcagcatatt gggtagccac atgacgattt gcgggaagta agtaatcaaa aacaagacga
    38581 ctaagataac cccataaaaa ggaagaagcg gtttcagcat tgcctctgct tttacgcctc
    38641 ctacacttgc accgacatat agtcctgtac ctactggcgg cgtgatggag cctacacaca
    38701 gattcatgat tgaaaacaac ccgtaatgta caggatcaac ccctacactt gtgacgattg
    38761 gtaaaaatat tggtgtaaaa atcaagatag caggcgccac atccataaac atacccacca
    38821 gtaataacac aagattgact aataacagaa taataaattt attatccgtt acgcccataa
    38881 tcaacgaact aattgcctga ggaataccgg taaacgccat ggcgaaagac atcatggaag
    38941 aagtagccaa taagaacatg atcgtccctg acattgctac tgattgaaac aacatattag
    39001 gtatatcttt tagttttacc gttttatagt aaaacatagc aatcaacagg gagtaaatga
    39061 cagctatcgc tgaagcttct actgctgtaa atatccccgt caagatacca ccgataatga
    39121 tgacaatcaa tagaaggcta ggaatcgcct cttttattat ttttccagca tgagccatct
    39181 gtcctttttc gacaacaggg tatttattct ttttagcaac gatgaatgct actagcatga
    39241 ttcctagcgc ccacaaagcg cctacgagat aacctcccat aaacaaagca gagatcgaag
    39301 caccaccagc aacaagtgaa tacatgataa aagcagtact tggaggaatg accatacctg
    39361 tcggagctga cgcgatattg accgctgtcg caaacttccg gtcatatcct tcttccactt
    39421 gctgagggat caacactccg ccaatcgcgg tagaagcggc aatggccgag ctagagatgg
    39481 aaccaaataa agcattccct aacacattcg tatgagccaa agcccccggc acgcgcccga
    39541 cgaacaacat cgcaaaatcc actagtttct tagctatccc tccattattc atgataatgc
    39601 ccgagagaac gaaaaacgga atagcgatca gcgaaaaact attgatactt cccaccattt
    39661 tttgagctga actaaaagca gaaacatcaa acggtataac taacaataaa gtcatcatcg
    39721 atgagaatgc aatacttata gcaatcggca tccctaatac aagcaacaca acaaatacaa
    39781 aaaataacac taatccggct tctattgcca ttttattcct ccatttttat attttttctt
    39841 gaattgctgg cttgttgctt aatgtatcga ttagattgat caggctatag ataatgatga
    39901 gtacccccga tacaggtact gacagataaa catatcccat aggaatactt aaagaaggcg
    39961 agatctgccc cattgtcaat gtgacagcat tccatccgcc atacaccatg atcatcgcag
    40021 caaataccag aaataaactt tgaacaacaa cttctaaaat tttacttttt ttgccagtta
    40081 atttttcact taaaaccgtt acggctaaat gtgctttttg tcccacaaca tacgcggaag
    40141 acaacatggc aaaccagaca agaccgaatc gaacaagctc ttccgtgacc gtatttggat
    40201 ttcctaaaac cgttctggaa aatacttgcc ataaaacaac agcgaccatc ccaacaagca
    40261 aaacagctcc caggatctct aataccttgt ttaaaatcat tttcatcaca gctacgctcc
    40321 ttgctcttgg atcttttgat aaaggtcttt gtaggtagga tcgtttttga atatatcatg
    40381 aagtggggca actgcctctc gaaacggtgt attatctaca tcattgaatt ggactccatg
    40441 ttcttcttgt gctaaagctt tttcttcttc aattgctttt gcaaaagctt caatttcaaa
    40501 aaccgttgat tctttcgctg cttcttcaat ggctttttcc tgctcatcag ttagctgttc
    40561 tttgatggca tcattcatga tgatgatatc tggcacacgt gtatgctcat cataggaata
    40621 gtatttagcc acaccaccat gtccagctgt atacaagaca aattcattgt tttctgatcc
    40681 gttgatcaaa ttggattgaa gagacgtgta cacttcatca cttcccatag gtacgggcga
    40741 accgcctaaa agctctacca ttttgatagc ggtttcgctt tgcatcacac ggatcttctt
    40801 tcccttcaaa tcttccggcg tatggatcgg accgtctacc atataaaagc tgcgctgacc
    40861 agaatcataa taggtcaatc cggtaaatcc taaatttttg gtcgattggt agattggctc
    40921 cattatttct tcattatcca tcaccttaaa gaaatgttct tcatcattga atagataagg
    40981 aactgaaaaa atcgaataat ctttagagaa actttccaac gctgaggcac ttacttttgt
    41041 gaaatctact gctcctgact gtgtcaattc gatcagttca cgttctccac ccagttgtcc
    41101 atctgggaaa tactggatct gtacggaacc atctgttttt tcttttacta aacgcccaaa
    41161 ttcattcatt gcatcaatta ctggctggct gttgcttgca taagcaaagc gcaaggtaac
    41221 tatctcattt acatctgcat ctgcgacagt tgccacacta gaattatttc cgcagccgct
    41281 tagacctagc agacctaggc taagcgaact tgctgcaaac agcagtgatg tttttttcat
    41341 atgggtttcc tttcttttaa caataagaga cgagcaattc tgtcaaacaa agcaccgtta
    41401 acgactgtcc ataaggcatt gctgtgattc cgatattccg ataaaaatct aaactgtccc
    41461 ccattcctgt cccgattgaa acgttttgaa cttctccttt ttcatcgatt tgttcaagca
    41521 atccttggat agcacgataa gcgacttctt tatattcttg tggtaaataa cgtttatgga
    41581 ccgctttcaa aataccgtaa gcaaatcctg cagttgcaga agattctacg taagaagaag
    41641 gatcatccaa caacgtatgc cataaaccgc tttcagactg ataagttttt aatgcacgca
    41701 cttgtgcttc aagtgtttcg atcaataatt tgcgcaatgc atcttctttc gataattcta
    41761 agatttcaat gatctctgga atagcaatcg tcaaccagca gtttccacga gcccaaaatg
    41821 cttcggcata gttatgattt ccttcaaacg tccagccgtg ataccacaat cctgttcgtt
    41881 tatccatcaa gtatttgata tggatcataa actggtaacg agcttcttct aaatattctg
    41941 ggcgattcaa cagtttcccg atttttgcca aaggaagcac tgtcatcatc aatgtatcgt
    42001 cccacaactg attcttattt tccggtccat atgtggcatg ctgtaacccg tcttcatttg
    42061 tccgaggcat gtcattcatg acccattctg cccattgttc taaataaggc aaatagcgtg
    42121 aatctttcgt gtcttcatac aagtaagcca tagtcaatag cggtgccatt gtattgacgt
    42181 ttttgggcgg agcgccttct tccatacgat cctcaaacca ttcattgacc acttgataag
    42241 cgcgaggatt ttttgtcatc tggtaatttt tataaatacc atatagaccg acaccttgtg
    42301 gccaattcca cactgtccag cttttgtcat ctactttcag tccatcaaag tccaacaaaa
    42361 attcaccatt atcgtctttg atcgttgtca ggttttcaac gagcaggtca attttttctt
    42421 tcactaattc tttaggtaca aaaatctctt ctttaataat catctttacg ccaccttttt
    42481 aaacgctttc attttatatc cttaatatag cagtaatacc gtccactata aatatcgctt
    42541 tttgaacaaa aactgtctaa aattgaccta aatgttaaat aacaaaagta actttcagtt
    42601 acttggaaat taaaaaaaga acttggagaa acaacgtttt ccaagttctt tttcatctat
    42661 tttcttatct tttttctacg ctttcttttg cttatccgtt gtaagcatca atgatgatct
    42721 gtttcaattc agagatcaat ggttctttcg gattagctgt cgtacattgg tcttcgtaag
    42781 ctaattcagc catacggtct acggttgtat ctagtgtttc ttgtgtgact ccttgagctt
    42841 ttagactcat gttgatgccg acagattttc ctaattcata aacagccgtt gctaaagctt
    42901 cgactaattc ctctgttgtt tcgcctttca gacctaagaa ttttgcgata tctgcgtaat
    42961 ctgtatctgc acggaaatag tcatatttag ggaacatcgc atgtttttgt ggatcttttg
    43021 cattatagcg gataatatgc ggtaaaagaa tcgcatttgt ccgtccatga gggatcccgt
    43081 attccccgcc gattttatgt gcgactgagt gacaaatacc taggaatgcg ttagcaaacg
    43141 ccataccagc cattgtagaa gcgttgtgca ttttttcacg tgattccata tcaggtgttt
    43201 ttactgattt ttctaaatag tcaaagacta acttgattgc ttgtaggctc aatccacgtg
    43261 tataatctga agccatgact gaaacatagg attcgattgc atgtgttaac acatccatcc
    43321 cggtatctgc tgtgacagat gctggaactg acatgacgaa ttgaggatcg acgattgcga
    43381 catctggcgt caatgcataa tctgctaacg gatatttcac atgtgtttca ctgtcagtga
    43441 tgaccgcaaa tggcgttact tcagaaccag tccctgatgt tgtcgggata catacgaatt
    43501 gtgttttttc tggtttgtcg atcttatatg tccgtttacg gatatccaag aatttttgtt
    43561 ttgcaccaaa gaaagatgtg tctgggtgtt catagaacat ccacattccc ttagctgcgt
    43621 ccattgcaga accgcctcca agagcgatta ctgtatctgg cttgaagtct gccatcagtt
    43681 tcgttcctgc gtatacggta tttgtcgatg ggttcggttc aacatctgag aagacttcga
    43741 tcttcacatc atttttacgt cgtgccaata cttcacgaac tgtatcgcag taaccgaatt
    43801 ggaccatacc agggtcacaa acgatcatga cacgttcaac gttttccatt ttctctaagt
    43861 acaatagaga gttcttttca aagaagattt ttggcggtaa tttgaaccat tgcatgttat
    43921 ttctccgttt cgctacagtt ttgacattga ttaagtttac agcagagacg ttacgagaaa
    43981 cagagttctt accataagaa ccgcatccca aagtcaatga cggaatcatt tcgttataga
    44041 tatcaccgat gccgccttct gcagatggtg tattcactaa aatacgacaa gctttcattc
    44101 gaagaccgaa tttgacatgc aactcttcgt tttctgaatg gataactgct gtatgtccta
    44161 atcctccaag attcaacata ccttcacaca aatcaaacgc atggtccgtg ttgttagctt
    44221 tgatcatggc aagaactgga gaaagttttt ctcttgatag cggataatct gggcctacgc
    44281 cttccaattc agcaatcagc attttcgttc cttttggtac actgattcct gccaattttg
    44341 cgatttccat cgcagaatgt ccaacgattg atggattgac cgcatatttt ccttcgttca
    44401 tcactgcatc ttctaatttt tgcaattcat ctggttttac gatataaact tggtgtgctt
    44461 ggaattctgc ttttactgct gcatagattt ctttatccac gatcacagct tgttcagaag
    44521 cacaaatcat tccattatca aatgttttcg aaacgatcaa atcgttcact gcacgtttaa
    44581 tttttgctgt tttttcaata taagctggta cgttacctgg acctacacct aaagctggtt
    44641 ttcctgtaga gtaagcagac ttgaccattc cagctccacc tgtcgctaag acgatcgcga
    44701 tacctggatg gttcattagc atagaagtcg cttcgatcga aggatgttcg atccattgga
    44761 tacaattttc aggagctccg gcagcgatag cagcatcacg taccactcgt gctgcttctg
    44821 cagaagattt ttgggcactt ggatggaaag caaaaacgat tggatttctt gttttcaacg
    44881 cgatcattga tttgaaaatc gttgtggaag tcggattcgt tgttggagtt actccgcaaa
    44941 ccacaccgac tggttcagca atttcaatca accctttttg gacatcttca ttgatcacac
    45001 caactgtttt atcatgtttg atattatgcc aaatatattc ggacgcatac atatttttga
    45061 ttgctttatc ttcgtaaaca ccgcggcctg tttcctctac agccatcttc gctaatggca
    45121 tatgttgatc caaagctgcc attgccattt catgcacgat atggtctact ttttcttgat
    45181 caaagctttc catttctttc aatgctgcat ttgctttttc tgccaaatca tcaatcattg
    45241 cttgtacgtc aattgtcttc gttttttctt tttctattac tttagccatc attatcctcc
    45301 taatgggtca tggttatttg ttaaa
//
LOCUS       DAZKCH010000013        42291 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000013 DAZKCH010000000
VERSION     DAZKCH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.013"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..245
                     /locus_tag="ACG84X_000756"
     CDS             6..245
                     /locus_tag="ACG84X_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126654.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            312..521
                     /locus_tag="ACG84X_000757"
     CDS             312..521
                     /locus_tag="ACG84X_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126655.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            581..1252
                     /locus_tag="ACG84X_000758"
     CDS             581..1252
                     /locus_tag="ACG84X_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFP9126656.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1305..3281
                     /locus_tag="ACG84X_000759"
     CDS             1305..3281
                     /locus_tag="ACG84X_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFP9126657.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            3294..4049
                     /locus_tag="ACG84X_000760"
     CDS             3294..4049
                     /locus_tag="ACG84X_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9126658.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            4046..4870
                     /locus_tag="ACG84X_000761"
     CDS             4046..4870
                     /locus_tag="ACG84X_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFP9126659.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            4880..5128
                     /locus_tag="ACG84X_000762"
     CDS             4880..5128
                     /locus_tag="ACG84X_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126660.1"
                     /translation="MKIIRILVFNLSFLAATILCCGLIFSQLSIYPRYQRLFIHFLNI
                     QCASMPLEVIKKLLINPIFMVSLVLLTGLVTWVLGKKE"
     gene            5171..7270
                     /locus_tag="ACG84X_000763"
     CDS             5171..7270
                     /locus_tag="ACG84X_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFP9126661.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLANA
                     ANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQDPVED
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(7308..9365)
                     /locus_tag="ACG84X_000764"
     CDS             complement(7308..9365)
                     /locus_tag="ACG84X_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFP9126662.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(9479..9691)
                     /locus_tag="ACG84X_000765"
     CDS             complement(9479..9691)
                     /locus_tag="ACG84X_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126663.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            9878..10345
                     /locus_tag="ACG84X_000766"
     CDS             9878..10345
                     /locus_tag="ACG84X_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126664.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            10342..10584
                     /locus_tag="ACG84X_000767"
     CDS             10342..10584
                     /locus_tag="ACG84X_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFP9126665.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            10602..10904
                     /locus_tag="ACG84X_000768"
     CDS             10602..10904
                     /locus_tag="ACG84X_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126666.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            10976..13030
                     /locus_tag="ACG84X_000769"
     CDS             10976..13030
                     /locus_tag="ACG84X_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126667.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETDEVEVDPVEA
                     NEESTWTEGDFQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKVKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            13030..15642
                     /locus_tag="ACG84X_000770"
     CDS             13030..15642
                     /locus_tag="ACG84X_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFP9126668.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFSEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            15639..18170
                     /locus_tag="ACG84X_000771"
     CDS             15639..18170
                     /locus_tag="ACG84X_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFP9126669.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PEQAKGMAGNDKSGLSDIQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEDKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            18222..18554
                     /locus_tag="ACG84X_000772"
     CDS             18222..18554
                     /locus_tag="ACG84X_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126670.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            18555..19148
                     /locus_tag="ACG84X_000773"
     CDS             18555..19148
                     /locus_tag="ACG84X_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126671.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            19311..21005
                     /locus_tag="ACG84X_000774"
     CDS             19311..21005
                     /locus_tag="ACG84X_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFP9126672.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEIVKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            21693..23570
                     /gene="ltrA"
                     /locus_tag="ACG84X_000775"
     CDS             21693..23570
                     /gene="ltrA"
                     /locus_tag="ACG84X_000775"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFP9126673.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            23701..24078
                     /locus_tag="ACG84X_000776"
                     /pseudo
     CDS             23701..24078
                     /locus_tag="ACG84X_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            24078..25283
                     /locus_tag="ACG84X_000777"
     CDS             24078..25283
                     /locus_tag="ACG84X_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFP9126674.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            25299..25943
                     /locus_tag="ACG84X_000778"
     CDS             25299..25943
                     /locus_tag="ACG84X_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126675.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            25954..26760
                     /locus_tag="ACG84X_000779"
     CDS             25954..26760
                     /locus_tag="ACG84X_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126676.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIFYIH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            26782..27012
                     /locus_tag="ACG84X_000780"
     CDS             26782..27012
                     /locus_tag="ACG84X_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126677.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            27558..27833
                     /locus_tag="ACG84X_000781"
     CDS             27558..27833
                     /locus_tag="ACG84X_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126678.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            27875..28297
                     /locus_tag="ACG84X_000782"
     CDS             27875..28297
                     /locus_tag="ACG84X_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126679.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            28316..29908
                     /gene="mobP2"
                     /locus_tag="ACG84X_000783"
     CDS             28316..29908
                     /gene="mobP2"
                     /locus_tag="ACG84X_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFP9126680.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            29920..30255
                     /locus_tag="ACG84X_000784"
     CDS             29920..30255
                     /locus_tag="ACG84X_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126681.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            30402..30596
                     /locus_tag="ACG84X_000785"
     CDS             30402..30596
                     /locus_tag="ACG84X_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126682.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            30628..33000
                     /locus_tag="ACG84X_000786"
     CDS             30628..33000
                     /locus_tag="ACG84X_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFP9126683.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            33061..34521
                     /locus_tag="ACG84X_000787"
     CDS             33061..34521
                     /locus_tag="ACG84X_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFP9126684.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            34532..36736
                     /gene="topB"
                     /locus_tag="ACG84X_000788"
     CDS             34532..36736
                     /gene="topB"
                     /locus_tag="ACG84X_000788"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFP9126685.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            36752..36901
                     /locus_tag="ACG84X_000789"
     CDS             36752..36901
                     /locus_tag="ACG84X_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126686.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            36975..37568
                     /locus_tag="ACG84X_000790"
     CDS             36975..37568
                     /locus_tag="ACG84X_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFP9126687.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            37584..38483
                     /locus_tag="ACG84X_000791"
     CDS             37584..38483
                     /locus_tag="ACG84X_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFP9126688.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            38486..38971
                     /gene="ssb"
                     /locus_tag="ACG84X_000792"
     CDS             38486..38971
                     /gene="ssb"
                     /locus_tag="ACG84X_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFP9126689.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            39337..39597
                     /locus_tag="ACG84X_000793"
     CDS             39337..39597
                     /locus_tag="ACG84X_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126690.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            40038..40244
                     /locus_tag="ACG84X_000794"
     CDS             40038..40244
                     /locus_tag="ACG84X_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFP9126691.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            40244..40495
                     /locus_tag="ACG84X_000795"
     CDS             40244..40495
                     /locus_tag="ACG84X_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126692.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            40510..40947
                     /locus_tag="ACG84X_000796"
     CDS             40510..40947
                     /locus_tag="ACG84X_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126693.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            40940..41647
                     /locus_tag="ACG84X_000797"
     CDS             40940..41647
                     /locus_tag="ACG84X_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126694.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            41812..42012
                     /locus_tag="ACG84X_000798"
     CDS             41812..42012
                     /locus_tag="ACG84X_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126695.1"
                     /translation="MNKIIPLLFVLFVGEILMRHAAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            42028..42207
                     /locus_tag="ACG84X_000799"
     CDS             42028..42207
                     /locus_tag="ACG84X_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126696.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
BASE COUNT        15576 a         6716 c         8659 g        11340 t
ORIGIN      
        1 agtagatggc gcgaccagtt ttagaggcga tggatatgga tactttgaca aaaggaaggt
       61 atgtacagct gttagctcgt ggttattcac ctaaagaagt attcaaagcc ttatctaaag
      121 gaacagatat ggaaaaagaa agattgcgaa aagaattcga ttattggaga acccataatg
      181 gaatcaagga tttgaaacca gcacggccag taattaaacg aaagaaaaag ataacccaag
      241 actgaagtgt agagcgtatg tgatcatagg cttttttatt tttgcaaaaa acaaggaagg
      301 taggaaaact catgaattat gaagaaatcg aaaacagaaa aaaagtgtcg aaagaaatgg
      361 aagaaaagtt actaaaaacg atgaagcaaa aacaccttaa aagattatct gtcgcgcaat
      421 atatcaatga tatgcagtta acaggaaaag agaaagcttg tttgttaggt tcaatgaaaa
      481 actttgaaca gttgagacga acttatagaa ttcattttta aaactttttc tatggaaatg
      541 agaaaaagtt tttttgtttt gtctgaaagg aggcagatgg atgaaaaaat ggttatttgg
      601 ttttttagga gtcactttaa tcgtcttttg cagtgtgttt ggctatgtta gctaccaaaa
      661 acatgaagga gaggtgttta agcaaaatat agaaaaaaag atgcccgtag atcaaatcaa
      721 tgcacatgca aagagttata aggaggatgc aacgaacgtc aataatgata tgtctttggg
      781 gcaaatgttg tccatacaaa aagaagcaat cgaaatgggc gtcaataaac aagtatttgc
      841 acaaattcag attcctgcac ttggtttagc attgccaatt tttaaagggg caaatcaata
      901 cactttgagt cttggagcgg ctacttattt ttatgaagat gccgaaatgg gcaaaggaaa
      961 ctatgtccta gcaggtcata acatggaaat gccaggtgtt ttattttctg atattcaaaa
     1021 gttgtcatta ggggaggtga tggacttagt tagtaacgat ggcgtctatc gttacaaggt
     1081 aacgcgtaaa tttatcgtac ctgggtactt taaattaatc gatggcgttc ctgaagagaa
     1141 ctctttcttg tctttgccaa agaaaggaga gaaaccctta ttaacgttgt ttacttgtgt
     1201 ttatacgtca caaggaaaag aaagatacgt ggtacaggga gagctacaat aacaaggttt
     1261 taatcaacgc gagtcgttga aatatgaaat gaggagagta aaaaatggca ataaatcggt
     1321 atgtaaaaaa agctggaatg cttgttggaa tgttaggaat cattgcaggc tgctttcagg
     1381 ggtatcaagt acatgcagaa gatgtcacgc aaaaaacacc accagagaag gtcaatatca
     1441 cggttcataa attaatgtac gatcaaggaa cgcaattgaa tgttgatatt gacgggatca
     1501 aaaacgatgg ttatacgcac gatcaatatc ctacaggtgt aacgaaatac aacaaggcag
     1561 attatggtga tgttgagttt acgttaggaa atattacgga tcaagtatta ccgagagaag
     1621 attctgatct aaccaacgcg aaagtggacg agattgtaca agatgtagaa gacaagggat
     1681 ctaacagtga gtacgtcaag aatgcaacca acaaaattac ttcagctgta gatgaaaatg
     1741 gtgagatcac ttttactgat caaccagcct atgtcaattc caaagggaat gtatatgtgg
     1801 tttatgaaag taaatccgct gctggattag tcacacaaaa agcaaaacca atggttgtga
     1861 ttgcgccaat gacagataaa acaggatcag gatttttaaa aaatattcat ttgtatccta
     1921 agaacattgt ttctaagttg agttttgaat taacgaaatt tggtgacgat ggcgcagacc
     1981 aaagcaaaca aaccctttta aaaggggcaa aatttgagtt atacaagggc gaacctggaa
     2041 aaggaacaaa attgggtgat cttgtatcgg atgatcaagg aaagctgact gcgactgatt
     2101 tgacgttagg aaaatactat tttgtggaag ttccttcgga agttgtagtg ggatcagatc
     2161 aagaaccaac agcagatcaa tatttattag gcgcagacgc tcgcaacgat gcgcacaata
     2221 aattaacctt tgaaattacg aatgatggcg tgacaagtga cttaaaagct tcatacgtaa
     2281 actataaagc accagtgatc gataaaacag taacaaatgg aacaggacaa gaacattctt
     2341 tccaaattgg tgacgcagta aattatcaag gaacgattca tattccaaca gacattgcag
     2401 gtggcgcaga cggtatcaca gtaaacggtg tgaaaagcga aacttctcct tacagtgtat
     2461 ttaaatgggg agatacagca ggtaaaggac tttcttatgt tgctgaaaaa gcagatatta
     2521 aagtaacaaa taatgatggt tcagtcgtat taaaagaaaa tactgactat aaaatcgaaa
     2581 attctgatag tggttttgtg atcgatttta tcgtaaataa tggacaagta agtgatacag
     2641 ttgcgaattt acatggtcaa gatctaaaaa tgacttataa catgtttgtg aatgatagtg
     2701 ctgaaatcgc aaatccatta acaaatagcg tggatttcgt ttataacaat aatccattta
     2761 atcaggaaga acaccacgaa aaaacgaaag ctgacgttgt gacttatggc gcaaaattct
     2821 taaaagtcga tagcggccta tttggaacag gtatcaaagc aacaccgctt gaaggcgcag
     2881 aatttgcagc taagaatgca gaaggtaagt actacggtgg acttactgat acagataaag
     2941 atggtgtcaa agaagcagtt tgggtagacg atgtagcaaa tgcagcaatc ctaaaatcag
     3001 ataaagaggg tcattttgaa atcactggtt taactgaagg agattactca ctggaagaaa
     3061 caaaagctcc tgaaaactat caaaaattaa caaaagagat ctctttcaaa gtagacaaag
     3121 attcatacaa agaagaaaac cgaatcacga tcaaaaataa tcaaaaagct tccgtaccaa
     3181 tgactggtag caacggtttc caatcttacg tattgatctc ttgcttgttg ctaggagcag
     3241 ggggactttc tgcagttgtt tactttaaga agaaagccta gaaggatcag ctaatgatta
     3301 ttcgtaagcc cccaaaaaga agagtcatgc acaaactgat gatatttttt tggttgctgt
     3361 cggcagtagc agtctattta attccagttg tggaaacaaa tgtagcgaaa tttcaacaac
     3421 agcaaagaat tttagccatt gaaaatcttg aaaaaacaga ttcttctttg gatgttgcga
     3481 aaatagagtt aggcgatcct gttggtgttc ttacaattcc aagtatttct ttaaaactac
     3541 caatttatga cggaacttcc gacaaaattt tagagaatgg tgtagggatt acggaaggaa
     3601 ctggcgatat tacaggagga aacggtaaaa atcctttaat cgcggggcac agtggacttt
     3661 ataaagataa tcttttcgat gatttgcctt cagtaaaaaa agggcaaaaa ttctttatta
     3721 aggtaaatga agaacaacat gcctatcaaa tttatcgaat tgaagaagtt aaagcagaag
     3781 aattacaaaa aaattattta gattatctta tgcctgaaaa agaccaagat aggatcacgt
     3841 taatgacatg cacaccaaaa ggtgtcaact cacaccgctt tttagtgtat ggtgaacgag
     3901 tttccttcag taaagaagat ttaaaactac agaaaaaagc aaaaaatagg aaatcaattt
     3961 cattggattg gcgattagca ctgctattcg cttttttttg cgttcctatt atttttattt
     4021 ataaaaaaat aaggaggaga tcggaatgaa taagagaaaa tggctgtttg tttgtgtagc
     4081 agctctcttt tctactgtag cttattcgca actgtctttc gctgacagca gtgatagtag
     4141 taccactcaa acaatagata attcaattac tgcaccaagc gaaacggaca gttcggagaa
     4201 tactacagaa gaaacggcag attcaaatat aagctttact gaatcaacga atccaacgtc
     4261 agaaagttct tcagagactt cagaaaagcc gcaagacgta gaagatacgc aagtgatcaa
     4321 gcaagccatt catattcaaa aaattatttc ttcgaatcaa atcaacaatc aaggcagtca
     4381 agtagcccag caagaaggta tcaatggcgc gaagtttatt gtctacgata tcacgaatat
     4441 cttagaagaa atgtcacaag atgataatga gaaaaatcaa tctgtagaaa taattgagtc
     4501 aaaattgaaa gatcgagcaa aaaaactttc atacgaccag ttgaaaaaag tggctgaagg
     4561 agaaaccaaa acgattgatg atcaggaagg cgtgattgaa ttttccattg aagtacctgc
     4621 aaacaaaaaa caagcatact atatcgttaa tgaatcaagc cctgaaaaca tttcaaacag
     4681 tgaagatatt gttttattga cacctgtttc aaatgaaaaa ggtgaatttt tgacggatgt
     4741 ttggttatac cctaaatcag agaaatcaga gccgaaagaa gaaattaaaa aagttgtgtc
     4801 aactggtgta aagaagaact tttttgaaaa ttgttgggaa ttttttgctc aattattttt
     4861 tgataattag gatgaaatga tgaaaataat aagaatatta gtttttaatc tatccttttt
     4921 agccgcaaca atattgtgtt gcggtttaat tttttctcaa ttatcaattt atccaagata
     4981 tcaacgattg ttcattcatt ttctaaacat tcaatgtgct tccatgccat tagaggtgat
     5041 taaaaagctc ttgatcaatc caatttttat ggttagtttg gttcttctta caggattggt
     5101 aacgtgggta ttaggaaaaa aagaatgaaa agcttacgat cgtttaaaaa aatattagat
     5161 ggagggcatt atggaaaata aaattcattg cactacggga agagtaatta ctttagtgtt
     5221 gtttttgttc cttcttcttt ttgcgagggg aactgcagtc caggccttag aaaaagttga
     5281 tccgagtcaa atcaaagaaa ataataatct ggtgctttat catgatagtg attcattgag
     5341 aaatatcgaa gtaactggga tcaatggatt taagatacta gatgagtatt caactaaaaa
     5401 acaaaaagta cttgcttggc caaaagtcaa agatttgaaa agtacgtcaa aaatcgttgc
     5461 ccattatcaa aaagtaggta cttatctagg aaaagaaatt gattgtgacg tgactttttc
     5521 taattttgta gcgcacgctg gggttaacca agacggatta gctaaaacaa ttaatggcaa
     5581 aaagtattat aattatttgc tctttgataa aaatatttat cgaggatttt tcatgcagtc
     5641 aatcaatgtc atgaatgcaa aactagaatt taagtatgca ggaacaaaaa caaaagtagc
     5701 tttgagtgaa ccacagccag aaattcaatc aaaaatgaga tcgatgagag cagctggtat
     5761 tgatttaaac gatacatttc tatccattta cagtttaaat ggacagtatc agcaacgtgt
     5821 gtcttggtat aatgacaata atgaatctgt cggtgaacgt aatattgata tgagagaatt
     5881 tgttgggtat gaaaaaatgg gtagcttacc ttattttgtc acaacagata cagcatgtgc
     5941 agaatacaaa gctcctgcgt tatcaacaaa caatttaact tcaaaagtag tgggaggacg
     6001 tgcagaaaag gcttatagct cgaatgatca tttcaccgat gttgtaggag ctgatactta
     6061 tcacagaagt ggtgtaacgt atacgcttca aggcgcttcc ccaacattca tgattggcgc
     6121 aaatacgaat agtatgatgt ttagctttga tactgcattg ctatggacac cacaaccatc
     6181 gaagcctaca aaagaagtgt ttaacaaagc taatactgaa gaggcagcac acaatattga
     6241 caaaaaagtg attccacaag gatcagatgt ttactatcat attcaccaaa agtttgatgc
     6301 attaacagtc aacacaatga acaaatacaa atcatttaaa atcactgata cctttgacag
     6361 caaaaatttt gatatggtat cggatgggaa aaactatgat ggcgcattgt ggtatgttga
     6421 agcgaatggt acttggaaaa aagctgatac aggaggaaag ttaactgtat caggtaatac
     6481 agtcacttat actgcttctg acagcttttt agctaacgct gcaaattacg gtagggatta
     6541 tattttgcag ctccatatga gagcaaaaaa tgatgcaaaa ggaattgcac caaatgtggc
     6601 tactgtaacg tttaacaatg atccgaacaa aggaacacaa aaaacaaata cagtagaaaa
     6661 ctatttctct cttaaaccaa ataaaaaagt ggaacaagat gggaaagatg ttgatggtcg
     6721 aaatgatggt aaaaaaggaa cgcctacagc tcctttaaat gcaggatctg aagtacaata
     6781 tctagtcaca caaaaatggc atacaaaagg tgtagacatt gcctcagatc attacaagca
     6841 atttagtatt caagatccag tggaagatcg tttgacgtat aaagaaggtt ctgcgcgagt
     6901 gatagatatg agtacaggaa aagatattac ttcagaaggt acactaacct atgatagcaa
     6961 ttcaagaacg ctgaagtggg aagcttccgc tgatttctta agtaaaaatc ttttagatgg
     7021 acgagaaatt cagctgatat ttacagctaa aactcctttg aatgaagaat tggatatcga
     7081 caaccaagca aaagtttcag tagaaagtat tgagaaagca actaatgtag taacgattgg
     7141 ggtaaaacct aacttacctc agatcattgt gccaaaaact ggatcgaatc atttagtgct
     7201 aactgttatt ggaagtatat tatttcttac tttagcatca ttgggctatg tagttttaaa
     7261 actcaaataa atataaaaac aaggctgaga atcagccttg ttttctttta tttgaagatt
     7321 ggattcgcac taataaatac attatctacg ccaattctac cagcagagtc aactacaaaa
     7381 ttatgaccta atccgagaat actttggtta ttataaagta aatttgcatt atgggcaggg
     7441 ctatttttcc atcctaccat ggcatcgata gcaccatcgt ctgataaaag gtcatcaata
     7501 tacagcccag tttgacttat gttttctccc ttagcaccgt agcagcctaa gctttccaat
     7561 aaatcttgga aagtaccacc accagggcga tagtgactga agctgacttg taattcttta
     7621 gctcgaatat ctgcagcctg ttgaacaata tcattgaatt gcattggggc aacaccattt
     7681 tgttggcgat aatcatttaa ccaagcaagt tctttttgac gcataaagtt acgtaattcg
     7741 tctaatgaaa tctttttata tttgaatgtg attgttttat tttgatcgac gttattaatg
     7801 gatcgttggc cgtttttatc cacggtaacg gtaggatcgt catttctgca caagaaataa
     7861 ttttgatcag tcatgttttt ccaaggagta gcaaagctat ccccttcgta tactgttttt
     7921 gattcactag agagaacagc gttggtatca gcatttacat gattaacagt cacattaaat
     7981 ttacgagtgt agttgaaaat ataattttga ctttcagtca cattgtttaa ggttactgaa
     8041 tttgttggtt ctacccgatc gtctaaaaca tatccttgaa tagaaggagc agttaaagtg
     8101 acactgtcac cgtgagtgac attgactatc tgttctttca aaatattaac tcgtccttcg
     8161 tttttgtagt tgttattgca caacaaattg atttgatgca cttgattata attgaatgtg
     8221 attgttgtat tacctgtgat tgttttgctt tgagtatcat taccaatcac tttgtagcta
     8281 aaattatctt tagcgccttc gctatattta aatgcttttg ccttagcagt gtaagtagaa
     8341 ccagaagtta cttttgcttg atctgtagca atcacttgac ctgtttgatt gtcaatatgg
     8401 ttaatagtaa ccgtatattc ttttggtgtt tcaggtttgt gttgcaaccc tttaaatgca
     8461 gcatcaagac tatttttagc attgtttact tgtgtttgag aaaccttaga atcgtctagt
     8521 acttttttag cattggataa agcagtctga aaattattcc aagattcttc tgtaaaatct
     8581 cctttagcag ttgattttac tcggttgtat aaagcttgta attcagcttt attcacagta
     8641 ggaactggtt ttttctttaa tcctttgtaa gcagaatcta atttattttt ggcactatcc
     8701 acttgctttt gagtcgcttt tgagtcattt aacactttct tagcattgtt taaagcggtt
     8761 tggaatgcgt tccaggtatt gtcggtatag tcaccttttt tcgttccctt aacgctcgta
     8821 taaagagctt ctagagccga tttattcact ttgggtttag aggtgtcagc gccataccaa
     8881 ccgatacctt cgtatttcca gccatagtct ttggttaacc attgtacttc tttccaactt
     8941 gcagtgtagt gatgtgagcc agattttaca ccaggaagga aaaggcggta gatcggttta
     9001 ttattttttt cggcagaacg ccaggcaggc ccttcataag tccagccgta atttttagtc
     9061 aaccatttca cttcatccca actagctgtg taatggtgat cacgaagacc tttattgtac
     9121 aaacgataga caagatggcc accgctagtc ggtgcttccc aggcggggcc ttcataattt
     9181 ccccatttta tctttactag atggtcacgt tcttttttgc tagaggtgta aaaatgttca
     9241 ttattatttg gattgtaaag gcgatacatg acgttagttg aagcagcgtc aacagatcca
     9301 gcaagactaa gtgaggcagc aaatgttcca atagctaaaa cagtttttgg attaaataat
     9361 ttcatttttt caactcctaa atttaattaa aaatgtttac atgattatta tatatcggct
     9421 aaccgatata gtcaataaaa aataagaaaa gccttatata attttggctt ttcttatttt
     9481 atttgttagt tgaagtatta atatcaacga tttcttcagc caatttattt aatttcatag
     9541 catttatgaa tctcatgttg tctatactag agcgtttgtt ggcaaggtca cttactgtag
     9601 ttaagggtac gccagattct atggatatag aacgaactga tttaccacta tcaaacagca
     9661 accattcgat tttcttttta tcagcgtaca tttcaatgct ccttcttgtt ttttctttat
     9721 tatagctctt ttttgtaatg aatcacaata tcaagagaaa aattttctat agaaaggtgg
     9781 atttttatga gtattcgttc tccgtgtatc caaatgaggt ttgttgctac tttcgttatt
     9841 tgatatacta aaaataaaca acgaaagaag gaataaaatg aagaaaaagc aactatggtt
     9901 tgtctctatg tttgcaatat tttttattat tttaagtgga tgttcaagta ataagaaatc
     9961 ggaagctaaa gaagataata gtttattgca accaggaact gtttggaaag aagaagtagg
    10021 tggtcttatt cataatttaa aaattataga tgatactacc tgggaatatt ctgaaagtgt
    10081 atggcatcca gatcctgtac aaataacagt taagaggcaa aaagactatg aaggtttaga
    10141 aagatacaaa atagtagatt ctgcaggcat tagggaattt ataaacaaac ctgattcatt
    10201 atttattgtt gttccctatg agaaggatgg cgtaaaaaaa ataatttttc ttggatctag
    10261 caaggatgag aagcgaacga aagagaaatt aattcatgat ggatcagagt taaataaata
    10321 caaattacaa aagactagtg agtgattgct agtcttttta tttatcctga aggaggaatc
    10381 acagtggcaa aagttaaaac accattcgaa aaagccgcgt ctaaaatctt agaacgccgt
    10441 ggtgtttctg aaatacagtg gaaaaaagaa gttcttgaaa aagcacaatt tgacctatta
    10501 cgaggaaaag ataaggactt agaagaatat atctatcaac gtgaacgtga aaaacttgta
    10561 ttcgatgaaa ttattaaaca ttaaaaggag cgaataatct tatgtttgaa tcaattacaa
    10621 tgaatttttt aactcaaccg aaagtagtag ctgcagttga tatttttaga gcattacaaa
    10681 ctgccgcaac tagtttgaaa aataatctga tgatttttgc ggctgtagct gccgttgcct
    10741 ccattgctct tggaggtatt ttcttcttct ttgggcgaag aggagctgaa aacgggaaga
    10801 cacacgtagg ttatgtattg ttgggggtag gagttatttt agctgccgct tctattgtag
    10861 tttcaatgtt ctcaatgttt ggacaaaccc cacaaggact ataaaaaaaa caagtaggag
    10921 gagtaaaaag tacgtggcta ctttttactc ctttttttat gaaaggagaa tattcatgtt
    10981 ttttacgatt tcaggaaatg caaaattgga taaagagtta ataagaaaag caacgaagaa
    11041 agtgggaaag cgtacttcct ttttaccgaa aacaattaaa tattctgtca ttgaaacgga
    11101 agaacagcta catgtgttag gacaagtgtt agaacaagag aatcaatctt ctgttaaatt
    11161 gactctcacg ttacatgata aagaaggaaa aatagaaaag gctggcacag aatacgtttt
    11221 tggcccactg gattatcaaa tttcagaagg tttttatcct acattgatag atttaatccg
    11281 ccttgatgtg tttaaagata cggatgaaac tatgagtgtg gaagagtctt atcgaaacga
    11341 aaaactgcta caagttttag aagaagagtt agagagcgac caaagaaaag tgaatcaagt
    11401 gagtgaagtc gaagtaaatg aagaagtacc atgggaacga ccaatctttc caaagaagga
    11461 gtcaaaagaa aaagagacag tctatgttga cgaacaagct gatattccga ctcagaaatc
    11521 gatatttgag gaagagaacg atgtgatggg tcaattggag gtagatccct ttgaagaaac
    11581 aatggaggat gaagagacgg acgaagtaga agttgatcca gttgaagcta atgaagagtc
    11641 aacatggact gaaggggatt ttcaggaata tattgaacca cttatcagtg aagaagtaga
    11701 aaaaaacgaa acagagatac aaaaggcaac tgtatttgat tatattttgg atcaatatcc
    11761 gccagagcat gaatggatga aagaaaaaaa caaattattt ttaaatgagc tttattcgaa
    11821 atatcaatta ccccaaacct atcaagcatt tttagagagt aaagaagaat taatctcaca
    11881 gggtaaaggc acacttttag aacagttaga gtctgtccaa tcaacaaatt ggcatgagct
    11941 tgcacaagaa gatttattag ccacctttga agaacgtcaa caagaaacag atcaagaaat
    12001 taatgagtat gcgacggaac agtcgtctaa ttgggagaaa gtaaaagagg aactaaataa
    12061 agaagaacag cgagtgattg aagaagaagt acaaaaagtc aaagagcggt acgaaaagaa
    12121 acgcgacaat gcttattcct tgtgtgtaga aaagatcaac aattttacta agacgaatca
    12181 agaagcgtta tcgaaagaaa aagaaaactt gttaaaagaa cgtattaaag aacgaaaaga
    12241 agagttctac cgcggtttac gtacagataa gctaaagatt agcaaagaat taaatgaaca
    12301 actgaataag ctatatcaaa caacgactga agttcttatg gaaaaacacg aacagatcca
    12361 gcaagaatta caagtacaaa ttccaaaatg gaaaaaagag tatgaaattc aacaacaaga
    12421 attgaaagaa caagaagaaa aacaacggca aaaagaaaaa gagcgtgaac aattagaaat
    12481 aagaaaacgg gaacaggatc ttgcggaaca aaaaatggcg atagaaaaac aacggttaga
    12541 gcaagaaaag gaaaaagaag cagctgctcg taaggaacgt caagaacaaa tggatacatt
    12601 gcgtcaagca cagttgaatt atctagcaca acctcaacca gtagctgctg ttcaaacgcc
    12661 agtgaacaac caagcaaatt taactccttc accccagcgt tcctttaacg gatggatggt
    12721 gggatgtatt gcaagtttaa gcttgcttct aggtggagga acagtatttg cttttaatca
    12781 tatcaatcaa tcttcacagg ctgattctgt agccacaacg gcgtcaatca aggaagaagc
    12841 ccaggaacaa gcaagaaaag agtatgaaca acaattagaa gaattattga atcgtaccaa
    12901 tcagtcaaca acagagtcaa gcatggaaaa tagcaaagag agtgatccta gtaaggctaa
    12961 agaaggatca agcgattcaa ctgtacactc aaacacttcc gaaagttcag aatcaaatga
    13021 ggtgaaataa tgcgtattag agaaacaacg agacgaaaag acaaacgatt caatttagaa
    13081 aagaataggt atctttctca tttctatcgc tatactcctt caggagaaga gctaccagaa
    13141 aaacatgaca aacgtatttc tcaaaagatt ttttatagtg gcttagctta tcttccttta
    13201 aactatgttg ttacaagaat accagaagca tttcatcgat ttgagattat tccaggaagt
    13261 ttacaaggag tgaatatttt tcagttacaa gaaatgccgc agttattcca ttttgattca
    13321 actggttttt ggaatccttt gaccccaaca acaagtttag gcacacgttt agttgtttct
    13381 acgatttgtg ttgttccagc tgtacttatg ggattgaaaa tggacatgtg gtttcgtccg
    13441 ctagcagatg gacaaaaagg ggataatcga ttaatgacct taaaagaaat ccaacagatt
    13501 tatccgcaaa tacctgaaac aaaaactact tttccaggtt atggaggtat tccaatcaca
    13561 cattacaaaa aatattggta cattcaaaca gatactgtta atacgtgtat tgttggtacc
    13621 tctcgatcag ggaaaggtca gattgaagtg ttagccacca ttgacaattt atctcgtgca
    13681 gaaaaacaaa gttcaatggt cgttaatgat ccaaaaacag aattatatgt tggtagtaaa
    13741 gatgaactag aagctagagg gtatgatgta tatgccttta atatcaccga tccactgcaa
    13801 tcaatgagtg ataatccatt ggcactcatc gtgaaatact ggaaacgagg agacatagat
    13861 actgcaacac agttaaccaa tactttcaca aatacgattt attatgatgc caacgcttca
    13921 gataacaaat actttaacga aaacgcgcag aaagctgtca atgcgcttat ttttgcgttg
    13981 ttagaacaag ctgatcaaac aggagattac tccaaattga caccgaataa tctcgttgag
    14041 cttctttctg agattggcgg ttttaattat tatccagatc cagacaatga attcaaacag
    14101 ttgaatgcct tagatgaatt tatgaatcag ttgccacctg gaaacattgc aaaaaaacaa
    14161 tatggggcaa cgaaaattgg atctgataaa gcgaagggaa atattttatc aacggcaatc
    14221 acgggattga atccatttac tctaacgaaa attgcaaaga tgacttctca atcaacgatt
    14281 gattataaat cggttgggtt tccaaaatac ttagatttga aattacatga aagtctttta
    14341 aatcaacgag tcgtagtaga attttatcat aagggaaaga aatttcatga agaacgtgtc
    14401 aaagtaggct ataaaggatt tagtgaaatc aattttgatt gtcatttagt tgcaggtgat
    14461 caagtttgtt taaaatacga tcatcaagga aaagaatatg tggcttggta tgaattttct
    14521 caaagagtat tgaaagacga agagggtaat atcgtttatc ggaaaaaacg aggagaaacc
    14581 catttgccag aattagaaaa agaagccgtt ctaacattag atgaggaaaa aagtaactta
    14641 ttagtagagt ctattcggat gcactatacc gataaaccaa tggctatttt tatgcttaca
    14701 cctgattatg atccatctaa ccatatcatt gttagtattt ttcttagtca gttatataaa
    14761 gaattatcta cgcaatgtgt taagactaaa ggagataaat gtcaccgcag gattcatttt
    14821 attttagatg aatttgggaa tatgccacca atggataata tggaaggaat catgacggtc
    14881 acagctggcc gaaacatgtt gtgggatctg tttattcaat cttatcagca actttatgcg
    14941 aagtatggag aacaaaacgc agcgattatc aaagaaaatt gtcagacaca tatttatatt
    15001 atgtcgacag atgataatac catcgaagaa ttttctaaaa aagtggggaa taagacggtt
    15061 gaacaagaga acagtaccat caattcatta ggtatgaata ctcatatcaa tcgcaatgtt
    15121 gattcagatc gtatcttaac tcctgaaaga atttctactt ttttagaagg agaaacgatt
    15181 gtactcgctc ctttaaaacg acaagatttg aaaggtcata aaatacggcc gtatcctatt
    15241 tttaatcatg gggaaacgaa tcttccttat gcttatcaat atattgaaga tttcaatcca
    15301 tcgtgggata tcaatgatat agacatacat tgtacacatg cggacttgga tcttaaggct
    15361 ttacaaattg attatgatta tttcctacca gatgaatatg ctagaaatct ctatcatgga
    15421 ctgcatgatc aattagaaga aaaaaacgaa gaaaatatgt tttataaaat cgttcaatct
    15481 tttgagaatg agacggctaa aaaattgtta attcaatttt acgaagaaca agcagcagat
    15541 cgacttcaag aatatgttga aaagttgatc aaaaataaag aaatttctga aatgattggg
    15601 aaacggttgt tattggaatc tgaaaaggtg gtgaaagaat gatcattgga ggaatttttt
    15661 ctggcatagc cgactggtgg tcaggcttat tcggagaagg ggatgcaaac cccaaaaccg
    15721 taacgaaagt cttacaagat tatgggaatt atctgcagta tcaagatgta tttagttgga
    15781 tttggaacac ttttctgtgg ggattgatta aaggattata taatctcaat actttactag
    15841 aaaaaaccat ttatcaaagc tttgatttaa aagacttatt gaacgccgct ggggtaaatg
    15901 cactatttca aagtttgatt agtaaggtat tggctctttt ttgtgtcgtc acattaattt
    15961 atttaggctt gaaatttttt atgagtaaac acccaccaaa agtcaaaaat atcttggtta
    16021 atttatttat ggccatgatc ttgatttttg gtggtagttc tttaatcgat gaagggttaa
    16081 atatcagtaa aagcttttac ggagacgtca ctgcagcaaa taaagcagat aaaacgggat
    16141 cacctgcttt tcaaattatt caaaataatg tgatcgatgt cagtacgtta ctagcaactg
    16201 acccgaataa agtagaatcc ctaccaacag ataaaagaaa tgctttaaca gcgaaaaatt
    16261 ttaaaacagc gaatatcaat gggattatta ctcctgaaca agctaaaggt atggcaggta
    16321 atgataaaag tgggttatca gatatacaaa aggatcggtt aaaggcatta caataccgat
    16381 tggaactaga tgataatggg aaagaaattc ctgttcaaat tagtgacgaa ggcttagcaa
    16441 aatatgtcta tacttcaggg tatcgtcgat acagtagtaa accaggtatt attttagctg
    16501 gtgaatcttc tttggcagta gcctatttat ttatcctatt tacgatcgtt acttgcatta
    16561 ttgagctggt atttaaaaaa ttctatttag tgattgccgc gtcaacggac tttgagacag
    16621 gtcaacggat gaaaagtgcg atagaagata tttctcaatc cttcttgtta ttggcgttta
    16681 cgattttaga attacgaatc tataccttaa tgctttcagg tatcggtgat ttgcatgcgg
    16741 caggaaagat caatggattc ttgtatgtcg ttgctttgat tgtactaacc attgcgctat
    16801 tcaaaggctc tcaatcagtt acgaaaattt tcggcgttga tacaagcctg aaaaacggca
    16861 gtaattctct tcttagcatg tttgccttag gaaatattgc gaaaaatgtg ggtagcggag
    16921 ctaaaaacct tgcaagtgct ggtaagagtg gtttaagcca tttaaatgat attcgtaaaa
    16981 atggatttgg ccatcgaaaa gatgttaccc ctgataacgg ggaagaacaa tcagacgata
    17041 aagctacaac tgtacctaat agtaagaaaa cagtttccga aatgttcggg aaagcgaaaa
    17101 atggtgtttc taaagccgca gaaggtcttg gttacgtcaa tgaacgtggg ttaaaaggaa
    17161 cagctgaaga tcttacagaa aaagccaaag acaccttaga agataaatta gacggcacga
    17221 gagctaaaga attggctgaa gctgtgaaga atccatccga agcactagaa aaacaaaaag
    17281 aaaaagcttc agaagtcaaa gaaggactaa aagatgcgta tggtgaagga caagtcaatg
    17341 cagcagtgaa agctaataca acaaccgaaa aagaaaatca agaaggtata gtgattcctt
    17401 cagtcaaaga tcaccaagaa gcgttgcact ctaatgaaaa ttcgattgaa gagaaaaatt
    17461 ccatagaaga aagaaattca gaagaaggaa aaaatggaca gttaccaaaa actgatccag
    17521 aacaatatcg ctataaacct aacagtgacc ttgaaaatga gaagcgaatt tcagatttat
    17581 caaaagtaaa tcaagaagac aaagcagaaa atgagggaca gttaccaaaa actgatccag
    17641 aacaatatcg gtatagatct gttaactccg aaaatgaaaa acgcatttca gatttaccaa
    17701 aacgaaatca agaagtacaa acggatgagg attccatcgt tctgccaaat gataatggaa
    17761 tcgaagttgg aactgaaaaa tcaacgaaaa ttggtttacc taaggcacaa aatttaccaa
    17821 tgaaagatag tcgtttgaat caattcaagg ataatgatca aagttttgtt catcaatcac
    17881 ctgcaggtac tgttcaaatg aaaccaagtc gtttgcctga aaatggaaat ctgacaactg
    17941 tttcttacaa tttatctgaa agtggtgaga cagggaatgc gtccgttcaa aatgttgtga
    18001 caagagaagc tgcaccaaaa cctattcaaa acgttcatac aggttacaag ccagcaaatg
    18061 tggcatttac tgcaccaaca aaaataaatg tgacaagaga aacaaaaaac aggaacaatg
    18121 cattgaaaga acaactattg agggatatca aacaggatat caaaccataa aaggcctaca
    18181 agttaggcct tttttctatg tatgaaaagg agaaatcatt tatggataaa tatagtaaca
    18241 tgaaaaaccc tccaagattt agtggagaat ggaagttttt cgcttttttc tttttagatc
    18301 tattaacgct tggtggctgc tttttttggg cgaaaatggt caataatctt gtccacttac
    18361 cactcttttt tgcactcttg aattatggct tatggattgc gatagcgtta gtgattgttt
    18421 ggcgacccta taataaccca ggtcaacgac aaatttttgc gattatcgag tctatttttt
    18481 ttgcggacaa gaaccattat catgcgttag atcctaaccg aaattatcat ggtacgtata
    18541 aggaggatga ataaatgcga gtcaaaggac aaaattcagt tgaaaggaaa tccattttgc
    18601 agtttggaaa accagaagag cgctctatct tggacttatt tccatataaa tcctgtacag
    18661 aagagggagt cttaattact agagaagatc attttcaacg ttattatcgt gtagtttcta
    18721 cagacgtgga aggattaaat gaacaagaga aactagaacg aatgaatcag ttgaccaccg
    18781 tcatgcgtac gtatgtgcca acaattaagt tagttagttt gaccacagag acggatctaa
    18841 cggaacaaat cgtgcaaaag cggcaattat tagataaaaa tcgtatggaa cagtccttag
    18901 gaagaaatct acaacgatta aaaaaatatg aaaagaaatt agtcgaagaa atccaggaat
    18961 tgaaacgagc agaacaagaa cgtcctgact taagcttctt tttcgtcatt gaaggaaaga
    19021 caatcaagga tttacaaacc agaaaccgtc agttaatgcg atctagtggc attttagggt
    19081 taaaaccact ctacaaaaaa gaattgatca agattctgta tcgaatgaac aatatgaatg
    19141 atgagtagga atggagaaga gagaatgaaa tatccgttga tatggttaga aaaagatgtt
    19201 ccgaaggaag agaccactag aaaatttcct cacactttaa gcctgggtaa gttgggaaaa
    19261 gggcaatctt ttaaccaagt aaagaatcaa acaagaagag gtgactgtac atgttagaag
    19321 caattaaaac agctttttca ccacaaaatg atcaaaaagt acttgatcca ttaaagcaac
    19381 taggaaatcg ggaaatagaa attgtaaaat ccaaagggta tgatttagat tttttaaaac
    19441 aagtgatgcc acaaggtggg ttaaattttg atgaagaata tgtgacgtat ggtaatggtt
    19501 attcacgatg tgtgacagtt tatcactaca caaaaaatcc tacgcttttt tggttggcca
    19561 atctcatgaa caatcctcat acagtggcca cactcgatgt tagcacagat gaaaagcaaa
    19621 aagtgattga tcaaatcaat cgtgccttag atgaattaaa tgatcgatca gataatgaac
    19681 gaaaagcgac tgaccgaaat aaaagcgcgg aagaatacct ggaactagcg gaatatgcta
    19741 gaaaattgac ttctaatggg gaaatttcta agcaagtcaa agtgagagta catgtttacg
    19801 gaaacacgat tcaagaagta gatgaacgag cgcaggaact gatcgaaaat ctcaaaggga
    19861 tggattatcg tgcggtgact tatctgcata aaaccaaacg agattggcaa tcgatgttta
    19921 ccatgttcga tgaacaagct gaatggttcg gaaatatcaa agggcaatca ctaccatcgt
    19981 taaacattgg cggaggtttc ccgttccacc accaaacgct aaaagatcca ggagggacac
    20041 aatatgggga aaccatgaca ggcggcccat ttgtctggaa tgcgacgtat aaaaatagtg
    20101 tacggttgtc tactaatacc ttgcttctag gaatgatggg agctggtaaa tcgaccgttc
    20161 ttaaaatgat cgcggaagcc catttagctg caggagactt tatttggggc tttgaaaagg
    20221 gaaaagactt tattcctttc ttaaaggaat ataacggtat tatggtgcgt ttagacggat
    20281 ctgacggaat gatcaatcct ttagagatat ttgccacacg gacgtatgat gaagcatcca
    20341 gtttatatga cgatggatca gtcaaagatt tgaagatcaa tgaagcagcg tcctatcaaa
    20401 cacacttaga caaagtggtc tatcaggtac agttagtgag tcctcagcta aaaggaacga
    20461 tgaaagcaga atttaagacc tacttaaatc gtttttatga agagtatgga acagtaccac
    20521 gcggctttac ttcctcaaat tcgcgttcaa atactgatac gcaagtcaca gggaaagatc
    20581 cagaagctta tccgacgttc aaagaatttt tagacttttt aggacaactg gaattaccag
    20641 gtgcttccca agagaaaaag aatcgaaaag aagaaatgga atccatcgta gaatccttat
    20701 gtgagacgta tggcatgatt tttgatggtc atagtacgat tcgacacctt gaccaacaac
    20761 agttggtctt ttttgacatt gactctatta caggcttaga tcgaggggta caacaatgtc
    20821 aaatgtacat ggctatgacg ttgatttgga atcaggcatt gattcaagga agaagacaac
    20881 gacgtttaat taaagaaaaa caaatggaag aacaagactt caaacgcttc ttggcgatga
    20941 ttgatgagtg ccataatggt gcgacctgtt ctgcagtgaa aagctgtggg ttgcaagtag
    21001 tctaaaaact attgtaataa ctcttataac gagaagtcaa atgagtgggt aacgccacaa
    21061 agggcttcca ctgatactcc gacatgcaac aagtagttta tgcagaccaa cgttgtgtga
    21121 agctcggtga agtcggctga aggataccgt aaggtaaaag aaatagtgaa taccacgaaa
    21181 gttctctaga ggtaaagggt gtatccgata agtcgggtgt ccaaaaaaac ttaatatggt
    21241 gagtatgtac aaacgtactg acgaactagc gaatgtactg tccgaaaggc atagctccta
    21301 gaaatgggag agacagtgag caaaaaatca ctcattgtgc taacttgtgg ttgagtaaaa
    21361 gtcgttgtta tgaaagacca tgctgcgtta caggcgtagg agaagttagg gggcaaaagc
    21421 tagcatctaa gttaaggcat gtggatagat ataagggaac aggggaagcc atcaacatgg
    21481 agagtgcata ctcgatgaag tggtagtaag aaatatgtga atgacaaata acttacttta
    21541 gtgatggtga aagtagagtc acgactgatg aaggttctgt aatggaactg gaggaacagg
    21601 ctcgattcgt ctgtaaaagt catgaaaccc gttcaaccat gggattctcg tatgactaaa
    21661 aaggtcacga gccaattgga gcgtgataaa ccatgacaaa agaaacaagt ccaaaagata
    21721 ggaagttgcg gcatgcagaa tattatggca tgacggaaat cttcgataag atatactcca
    21781 aaagtttgaa gggagataat ttcaagaatc taatgcagat tatcatttct gataacaaca
    21841 ttgtcctagc atatcgtaat atcaagagaa atcacggtag tgtgacaaga ggagaagatg
    21901 gagtaacgat taaagatatt gaaaatctca accgtaatga attcgtagaa attgttagga
    21961 agcgattcgc acattataac cctcggaaag taaggcgtgt agaaattcct aaatataatg
    22021 gtaaattaag accgttgggt attccatcaa tatgggatag aatcgcgcag caatgcatct
    22081 tacaagtatt agaaccaata tgtgaagcaa aattcaataa tcacagctat ggtttccgcc
    22141 caaatagatc agcagaacac gcaatagcag attgtatggc ccgaatgaat caaagtcaca
    22201 tggaatatgt ggtagatgta gatatcaaag gtttcttcga cgaagtcaat catactaaac
    22261 tcatgagaca aatctggtct atgggtatac gagacaaaca gcttctctta atcattagga
    22321 aaatgttaag agcacccgta gtacttccaa atgggaagtt gatataccca acaaaaggaa
    22381 caccacaagg cggaatactt agcccattac ttgcgaacat caatctcaac gaatttgact
    22441 ggtggatagc aaatcagtgg gaggaaaaag atgccaaaga gctaaaacat cattttagga
    22501 aaaatggagc ttgggataaa ggtaatatct atcacaagct cagaaagagt acaactctaa
    22561 aagaaatata cctagtgaga tacgcagatg attttaaaat tttctgtaga aattataatg
    22621 aagcgaaaaa agttttctat gcaactaaaa tgtggttaca ggagcgtcta aagttaccaa
    22681 tatctgaaga aaagtcaaaa atcacaaatc tttcaaaaga agaaagtgaa tttttaggct
    22741 ttacgatgaa attagtgacc aaaggtaaca aaaaggttgt taatacgcat ataggtacaa
    22801 aagcacaaag catgattaaa gtgaaactaa aaaaacaaat caaacgaatt caaaaaagtc
    22861 ctaatagcaa agataccttt atctatattg gagtctataa cagtatggtt attgggattc
    22921 ataattactt caaaattgcg actcattgta gtgtagcaat gcgaaaaatt gcaagagaac
    22981 tcagaccaag ttttgaaata cgactacgag aacaaggaat ctcaaaagaa ggacaatacg
    23041 gaaagtacga aggatacaag ccttacctac ggtcaggaca aatacgatat ataagagggt
    23101 ttccaatatt accagtaggg tatattcaac acagacatcc gatgtgtaaa aaaagaaata
    23161 ttaataaata caccgaagaa ggtagggaag ccattcataa gaagcaacaa accgtagaag
    23221 aatggaagat atcgtggttg tgtagcaatc cagtgcttag taagagagca acgattgaat
    23281 ttgcggacaa tcgaatttca aaattcatcg ctcaaaaggg aagatgtgca gtaacaggtg
    23341 aggagcttat cttatctgaa atgcattgtc atcatattat cccttatcat gaaagcaaaa
    23401 gtgatagcta tgaaaaccta gtgattgtta ctgaggaggt tcatcgggta atacacgcta
    23461 cacaaagtga aacgattgag gaacttctaa aatatctaaa attaaatcca aaacaaaaag
    23521 aaaaactcaa tgagttgaga ttaaaagttg gtaacgaaga aatatcttaa taaatatttg
    23581 taggacggga aaacagaatg tcttttatag acgagggaac gccgtatgcg gtgaaagtcg
    23641 cacgtacggt gtggactggg ggaaaagacg gagataatat caaactctta cctatcagta
    23701 tcgattaatc cagattttat tgaaacggta aattatgtca caaactttca acgagaaatg
    23761 cgtaaagtag aagcaatgac tgttttagct acacaatccc cacaagaaat ggtgccagaa
    23821 aatatgtctt ctgataactt ctcgaaactg aagaaagtct ttgaattttc ttctacgaag
    23881 atctttatgc gtatggatga atctatttta cgtcatatag aaggattagt gggtaaatca
    23941 atgacgaact cagaattaga atccattcct caacaaaatc aaggagacgc tgtgatcaat
    24001 tttggctcaa aagaaaccat tcgtgttcat tttagtccga acaaacgtca attaaaattg
    24061 tttgatggag gaaaataatg gaaaaccaaa atgaaagttt aatcaagcag tatgttaagc
    24121 gtcgtgcaaa gcggcgctta tttttgtggt tgtttggtac ttctgcaggt ttgattacta
    24181 ttttgatcac tgtgttcgtg accctatttc taatacttgc ggcgggctcg attgataatt
    24241 cggattcaga ttcaagcagt ggtggcgaag cttttacagg agaatattcg gaaggcttac
    24301 cgatttataa agaaatcaaa ggaagaggcc ctttttctga tgagattgcg caatatgccg
    24361 taggtgcagc agtgaaatat aaattattac caagtgtgat cctttcgcaa tacggttacg
    24421 aatcagcgtt tggtacatcg gcgtccgcaa gaaatgatct caactatttt gggattactt
    24481 ggtttgatgg ttgtctgttt cctaaaggaa ctgcacgagg aattggtggc attgaaggtg
    24541 gctggtacat gaagtttccc aactcaaaag ctgcattttc ctattacggc tttatggtag
    24601 ccacacaatc caattttaat gcttgtgtag gaaataaaag ccctggcgca agcttattga
    24661 tcttaggacg aggcggttat gccgctgcag gaattacgga agatagtccg tattatacag
    24721 gttgtatgtc aattatcact tctaataaat taaccgaata tgatgaattc gccatcaaac
    24781 attggggtga aggtggcaat aacaacggca cgattactgg tgaatggacg aatccattcc
    24841 ctggcagcag tttagataaa agttccttca gcggtggtca attatttgga acgaatccag
    24901 gcggtgaatt ccgtccgaac ggcttccatg atggattaga ttttggttca gttgatcatc
    24961 caggaagtga gattcatgcg gttcatggcg gaaaagtcgt gtacgttggc aatcctggta
    25021 tttcaggttt gggtgcgtgt gtgatcgtga ttaattacga tggcttgaat atggtgtatc
    25081 aagaatttgc aaatagtaca ggaaattctc gagtgaaagt aggcgatcaa gtgaaagttg
    25141 gtcaagtaat tgggatacga gatacagcac acttgcattt aggatttact cgaatggatt
    25201 ggcgtcaagc acaaggacat gcattcattg atgatggtac atggatcgat ccgttaccat
    25261 ttttgaatag cagtaaaaaa tagatcagga gaaaaaatat ggaaaataaa acgttaaaaa
    25321 tcgtcttaac agctgcaatt agcgttagtt taatcggcaa tattgcgttg ttttggcagc
    25381 tgaaagagga acaagcagca aatacctata aaattgaaga agtggctaaa aacgcgtctg
    25441 agaagctcaa aaaaaattcc tctgaggcac aggcgaagat cgacaagtta aatcaaacca
    25501 tcaatgagaa aaaccaagaa atcgatcagc tgaagcaaca agatggcaca aaagcaaaag
    25561 aggaagtaac tgaagcacaa agaaagacgg cagaagagtt cggtcaattg gccattgata
    25621 aatcattaag cagaaatgaa ttaacggaaa aactaaaaga tgtcgcaacc caagaagtga
    25681 tcgacaaatt aagtcctaca gacgatgatc accaacatga tgattacgga agttactcct
    25741 ttacattagg tgacgtgcaa acttacgctc aaacaagcag tgtaaaagag gaacaaaatt
    25801 ttgtcgtatt tgttgattat acaatcggca atccgcaatt caaagatgtc aaaccacaaa
    25861 aaataaaagg tggattaact gtcactgaaa aacaagtaga tggtcaatgg aaagtcatag
    25921 actttagtta tttcactcgt taggaggaag aaaatgagta agaaaaaagg agaaagacaa
    25981 cgtttcaaaa aacgaaaaag ttatcttaga tggctgggaa tctttatgat tctcggcttt
    26041 ttgattcttg ctagtccgat ttatacgaat cagaaggtag atataccaga tgaggtaagc
    26101 acgaacgcct ttttaaacac gaaagagctg acaatggttt caaaagaaaa aggagcgaac
    26161 cagcaattag tttttgaatt tgcgatcgat gatgaagatc aaagcttgtt aaaagaactg
    26221 gctaatctta attatcgcgt agaagtaaag acagctaaag gggattatca agcaatacga
    26281 gccaaagtga ttaaggtgtc tgatgattat tttgcagtga agctaacgca tgtaccagaa
    26341 gaatatatcg ccatgcgttt aaccattatt cctgaaaaaa ttgatccaaa agtggatatg
    26401 caagaaccac aagatctgat tttttatatt cacgaagata aggtcaaaga tcacgtgaaa
    26461 gacgaagatt atgaacaaca tgcgatcaat tacaaagtga aaggatacaa gaaagaacaa
    26521 aaagcagctc aaaaacaaat ggaatctttc caagcaacca ttgatttgaa tgaagaatta
    26581 gtgaagaagc taaaagatca attgccttat caagtcgcag atgatcagga aaatactgaa
    26641 aacaagatta atagctacca gcaagaaatt gaaacatcga aaacgcaact gaaagatcaa
    26701 gaagagatca ttcaaaaact tcaagaaaaa attgatcgta tgacaaaaga aaagatttag
    26761 aaggacaggt ggagtgaaaa aatgaagcga acaaacttgg ctgacaaaga tactttcgct
    26821 gagcagaaag tattgattaa agcctatctc aaagttgtaa aagctaaaga aatatgtcga
    26881 gaagtgaatt tatctaacac aacaatatct gagttgaaga atggtcgaaa gaatttagat
    26941 accttaaaat tcagatcatt tgaagctcta tatgtagctg ctaaaaaata ttttacagct
    27001 gataacaaat aaaaaacagg agtattttat gtgaaaaaag tatataaaaa atgcttatga
    27061 atcagctata tcaccttaac catttgttaa tgagatggga gaaaacatta accacgattc
    27121 taacgcaaac atcaagcaca taaaacattt aacactcctc ctttctggct gaagatttca
    27181 accaaacagg aagacagcgt atcaattata gcatacactt tttcttaaat tcatttttca
    27241 tatgacaaaa tatttccttc taatcgacaa agttagaagg attttttatt gtctaaatac
    27301 acaaataacc ttaattttta aagagcataa ggaaacgtga tatcactttc tcacgaaagg
    27361 tgttaggtag gctgtgccta ccacgtttct aagaaagata aatgatatca aaattttgga
    27421 tttgtgtgta gatttgtggg taggatgaaa gcgaatgtgg gcagtaaaat aagcgtttgt
    27481 gtgtagcaaa atcaaaaaat gtgtagggat atgtgtagct acacatatcc ctacacataa
    27541 taaatttgga ggaaaatatg gacttattaa ttagaaatat tgaagaaaag tatattaata
    27601 aaattgacaa acgttgtgaa gaacttacgg tcaagactgg caaaaaatgg agtcgaaatc
    27661 aatacctaaa agttttgatc gaaaatgatt ttgatcacgc tcttctgaat tataaaaaag
    27721 accaatttga tcggttgtta gaaaaatttg tggatattca aacttataat acgaaaactt
    27781 tagaagaata tattgcaaca aataatcaat taattggttt gttaattgaa taataaaaat
    27841 agtattgtga atttataaaa ggaggaaatc aattttggca aaagcaacaa gaaaacatgt
    27901 atatctttac gatatgcata tcgaagtact tgatgaaata atttctactc atgaagatat
    27961 atctaattat agtgaagcag tcagacattt gtgtatgatg tatgatccaa aaatcgaaga
    28021 aaaaataaat ccaattcaaa ttaaattgaa tgcaatggga aaagaaattt ctattttaac
    28081 cgaaatggtt tcagagtttg cggatcttca tttgaaagat acaggaatac taattggtac
    28141 aaattcaact gtttatcaag aagcagaaga acgtgtggaa ggaaaaatta aatccaatca
    28201 aaccaaaaaa tattcttcta agttaaagaa accagtgaat gaatctgttc ataccagagt
    28261 agatccattt gatccaacga agattctaaa aagataaaag tagaaggaga acgtgatgaa
    28321 taaatcgcct gcagttattc ttacttgtca atttaccttg cccaataaaa aatctttttc
    28381 aacatacatt gattatatga caagagaaaa agcactggaa gaaatggaac gacgtacgcc
    28441 cgaagaagaa caggaactgc aacgaatcaa gaatgcttta gaggattttt atattcctga
    28501 aggagaaact ttttcggaaa gtaagacgga taaagaattc agtgaaacgt cgaatgaagc
    28561 tcaatcgttg atggaacatg gaatcaattt tgacaagtta gaggaacaag attttaccaa
    28621 atatctttct tatatgaccc gtcactatgc gttagaacaa aagaaagaac tgacgcaaag
    28681 ggaacaaaaa gaataccaac ggttgaacca agcaatgaaa aaatatcaaa cagagccaca
    28741 taaaaaagct tcaggaaatc ttcctggagt tttttctatg gcttcagacg aagtgaaagg
    28801 aagtgatctg aaggagatca aacaaatctt ccaaagagga caacaaaaag gctcaatcat
    28861 ttatcaagat gttatctctc acgacaattc gtatcttgaa aaaatgggct tgtacgatcc
    28921 caaaacagat accttagatg aagaaggttt gaaagcagct ggaagaaaaa tgatggagac
    28981 attattcgag aaagaacaat tgaatgaaac aggttactgg atggcaacga ttcaccgtaa
    29041 cactaagcat atccatattc attttgcagt tgttgaaaaa gaaaatacgc gtaaaccgta
    29101 tactgagatt gaaaatggtg tgagttatat cgtaccgaag gggaagagaa gacaagcaac
    29161 attagacgca atgaaaacca attatgtaca tgagttagaa cgtttctctt atgaaaagga
    29221 tcgaatgatc ggtatggaga aacgaaattt attgacacga aaaagtgatt tgcgtaacac
    29281 cttaacaaaa gtagtaaaag aaccagcacg ttacgatcga cacgccatga acttattaaa
    29341 tgaagtatat aaaaccctac ctgaaaaacg ttcggaatgg aattatggag atgaaaatcg
    29401 aaccaagctt tcaccattta caaggggaaa acttgatgag ttaaccaaat atgttttaac
    29461 aaaagaacct ggatatcaag aatatataca gatttcaaaa gcattgaaag aagaagccaa
    29521 aagcctttat ggggaaagca aaagagaaac aaagaatgca gaaaaaaacg ccctctttga
    29581 tttaaaaaag cgcacaggaa atgcgatttt aacagaactg aagagacagg atagtcaaat
    29641 aaaaccatta atagaaagtg tcaatcagat gcaatctatt tacaatgaac gatcctttcg
    29701 aacactcaaa cagttgccaa caaatgaata caagtatagt tatcaagaat tcgtaaagcg
    29761 taggaaacaa ttccaacaaa gagttgtcac gcagcgaagc ttgcgtcaat taaatcgaac
    29821 aattaatgca catgaagaaa aataccacgc aagtaaagca tatgaagagc aacagcgaag
    29881 aatccaaatg gaacaagaaa gacaatagga ggaagagaaa tgaaacaata tttagatcaa
    29941 tggaaagtca tagaaggatc actaaaagaa gaacgaatcg aacaacttcc tgattgttta
    30001 gaaaaagagc atttgtttca gataagcgaa atgttgagaa acgaacagtt tgatccaaat
    30061 caatttttag ttgttgagta cccagctact ggtgtgtatt gttgtaatca tgtgaagggt
    30121 gaaaaatatt ttattattca agaatacgaa ggtaagttag cgccttatta tactacttgg
    30181 gaaataaatg aagagggaat caataatttc ccatgtgaaa gcattgaaga gtctatttct
    30241 ctcacggaat gttaaataaa tagagacgta aaagagtcct gaacgtgatt gtccaggact
    30301 ctttttcaat gaattgtttt ccgccaattc actgagtggt gcgattcaat tttattatat
    30361 caaaagaaag tgagattcca aagtgaaggg aggaagaaga aatgactcag acaacgattg
    30421 gtgttgtggt tgaaaaaagc agggataatc tcgtttttgt gacagaaatt caaacaggta
    30481 gagcttttgt agtcacagac aaagctgcaa aagcgtatca aaatggcaat attttaacgt
    30541 taaatctgac tacgaagatg ttcgttgatg cagtagaaaa ttatccattt gtttagacaa
    30601 acgatatttt acaaggagga aacggacatg gcagaagaaa aagaaccact agataatagt
    30661 cggttgggaa agtccaaaag aaaattagta cggttgcaaa acgaattaaa taatcaattt
    30721 caaaagctat ttgatcacca aaaattgaca aatgggcaac caatgaatga caaacgaaat
    30781 ggtcgttcat ggtttaacca gcaagaaaaa atagaaaata aaatacaaag tttgagagaa
    30841 gagatcaagc aacaagaaaa acaggtagaa aaacttgaaa gacaagaaga gctaaaggaa
    30901 atgggctata acaagtacgg cggactggat atgacgatcg ataatattcc aagaatcaaa
    30961 gaagaaatcg aacgctttga aaaaggtgaa tcgacttttt cagccgccac gatccgaaaa
    31021 tatcaacgga agttggaaac attagaacag ctgaaagaaa aatcagaaaa aggaaaagaa
    31081 aatatcctcc ctgaagtaca agcgatcatt gacagcggac gagtgacgca atggaaaaaa
    31141 aatccaacca tttatttttt gaaaggctat cgaaaagttg ctttagaact gaatgaaaac
    31201 gggggatttg aggaatcaaa aaaataccaa gccacgtcgg aagaggaaaa agcagctgtt
    31261 cgtgaattac ttgaagaggc tgcaccaact gattctctga aggagaaaga aaaagatcat
    31321 ttctatcgag tagaattcaa cgaaaatgat ccagaaaaag gattgaaaag ttatggtggg
    31381 gagatcgtaa cattagaatt gatcgatcaa cttaaaacgt tggataacca atacgctgca
    31441 gaagcaggtt attataaatt ctattttgaa gaagtgaaga acggagaagt agtagatcag
    31501 atccgaatgg atctagggga tggcgtcaac agtaatcacc ccatctattt agagttagca
    31561 aaattgtgcg aacaagtacc tgagaaggaa caaaaacaat cggtcaaaaa tgaacctgtt
    31621 tcgaaagaac aaatgcagtc gaaagaaaca aaaacaaaac aaaagggcta tcaaaaacga
    31681 acggcagaag agatcaaaca agaagttaaa tccctttcgc aacaggcact ggatgcggtg
    31741 aaaaagcata cccattcttc tgaagacgtc aaagaacttt tgaactttat gtctcgtttt
    31801 ccagaacgat cctttagaaa tcaattattg attgaggaac aatttccagg tgcaacggct
    31861 tgtttaggtc gtgccgcgtt gaaaaaagaa ggaatctata tcaaaaaagg ggaacaaggg
    31921 aacaagatct ttgtcagaaa aacggtcaaa ggattttatg agaaaggacg tggctttgtt
    31981 cgagaaacag aagctacacc agaagataaa aaacgaatcg aaagtggtca aatcgaagtg
    32041 atcaaaaaac cttactacac gattgaaaaa gtgtttgata tcacacaaac acagttaaaa
    32101 cctgaagact atccgaaaat ctttccgaac cgtgtctttg attttcaatt ggataaaaaa
    32161 ggacagtcag aacttcaagc tgggattcaa gcggtagcca acaatattgg aatacaaatt
    32221 cgagatatga cagaaagtga agtctatcaa agagaattag gacaagcacg tggggcgtat
    32281 gttcgtaacg aatttactgg cgaagaagaa atcgtcatga atactcgaaa tactcctacg
    32341 cagcatttag ctacaagtat tcatgaatta gcccatgcaa gaatgcacaa attttcagaa
    32401 ttagataccg caactaaaga attgcaggca gaaatgactt cttatattgt gtgcaaacat
    32461 tttggaatgg acacttcgga gaaagctatt ccttatattg cagcatggac gaagaatggt
    32521 cagacgttgg atgataagga agcggcggaa cgtgggaaaa tcatgaatga tgtcagccgt
    32581 gtcgcaaatg aattcattca aaccatttct aatgaaatca atcaatacag agaaagagaa
    32641 ccagagatcc aaccagcaga agtgaagcag gagcataaaa atactgtaga aacggcagag
    32701 aataagaata ttgtgcccgt tggttcactt tggatcgaca agaaagacgg gaaagtaatg
    32761 gaagaagata cgggtcgaac gttacatttg aaggatgcgg cgtttattga agatccgcag
    32821 cataatcaag tgattttaaa aggaaaaagt tatggaaaag agattcaaac ggcgttacct
    32881 tcagaagaat ttgcgctagg aaatccattc cgattttcac ttgaaacagt gtcagaagtg
    32941 gccaaacgaa aaaatgaaat ctattatgaa caacaattgt cacaaaaaga acgcgtataa
    33001 aacaagtaaa aaagactatc tgaaaaacgg atagtctttt ttcttttggg aggtttgaaa
    33061 atgaccgaaa aaaaaatgag tcttattgat cgatgtaaac agatcgatat agtggatttt
    33121 gctcgaaaca atggaatggc tgtagtcaat aaaggacgag actatcgctt agaagaccat
    33181 gattcatttg tttttgatcg aagaaaacaa cgtttttatt ggaacagtca aaatattagt
    33241 ggcgacatta ttgaattagc taaacttttt ttcatagaca aagagatcca agactctaag
    33301 caacaattta aagcagccac tgattttatt ctaaagaatg aagacaaaac agaacgagtg
    33361 gaaaatcttc attttgaaac agaaaagtac aaagatcacc ccgttgatta tcaaccactc
    33421 acagaaaaag gaaggaatta tctgaaggaa gaacgaaaac taccagagtg gctgattgat
    33481 tatgcagaaa aagaagggtt gattgccgaa ctaaagccaa aatatgaacg gcaaaatttc
    33541 ttagttcgag acgatcgttt agatcatgcg gtcgcctttt tatggaaaga tccacagaca
    33601 aaagagacag taggggcgag ttatcaagga acgttcattg attatgaacg ttttggtgag
    33661 agaggcacat ataagcatat agataaaaat tcgacagcga atcatggctt taacctaaag
    33721 atcggtgacc ctaagcagtt aaaatttttt gagagtagta ttgatttact tagctatgct
    33781 gcactgaatc gtgatcagtt aaacgatacg tggttagtct ctatggaagg gttaaaacac
    33841 catgtgatca gtcattattt tggtgaggca gtatctgaat tgagaaagaa acaagccttt
    33901 cctcaatcca tcgagatttg tgtggataat gaccgtgcag gacatatttt ctacgaaaaa
    33961 gaacaattaa tgggcgcagt cgatccattt acgaatcaga aagtacgttg tgaacgagga
    34021 atcgctaatg attggcaagt gccaaaagaa tacaaaatca tttatgaaga agtcgcaaaa
    34081 gaagaaaagg tcacaccaga agctattatg gccatacaca agacagaaaa caatctgcaa
    34141 ttaacgaacc aactggtttc cgctcacaaa gtaaatgcgt tttttggcca gcagctttct
    34201 gttaacgatt caatagaagc cattaatttg aaagatattt gtagagaagt cgcaaaagaa
    34261 ttaaaagttt gtgaacgcgt ggatggtacg tacgattttg atcgttttta tcaagaaaaa
    34321 ggggatatta atgcgcagat tcttttctct tataaagcag aacaatacta caaaggctat
    34381 aaaaatcatg aacatgaatt tatacctgaa gtaaaaaagg actggaacga tcaattgaag
    34441 catgagatcc agcaacaaga aatcagaaag caaaaacgtg ccatgttgtt tcaacaaggc
    34501 agacaacaag aaagggagtg aaatcgtcat gatgaaaacc gttattttag cagaaaagcc
    34561 gtcacaagcg aaagcttatg ccgatagctt ttctaaagct acccgaaaag atgggtattt
    34621 tgagatccaa gatcgattgt ttacaggaga aactgtgatc acgtatggtt ttggtcattt
    34681 agtcgagtta gattcgcccg atatgtacga tgaaaaatgg aaacaatggg cattagaaca
    34741 tttgcctatt ttccccaatc aataccacta tcatgttcct aaagataaga aaaagcagtt
    34801 tagtgtcgtc aaacgacagc tgcagtcagc tgatacgatt gtgatcgcga ctgatagcga
    34861 tcgtgaaggg gagctgattg cctggtcaat cattcaacaa gcaggcgcca atcaaggaaa
    34921 aacctttaaa agactttgga tcaactcctt agaaaaagaa gccatttatc agggattcca
    34981 acagttacga gacgcagaag agacctatcc aaaatttgaa gaagtacaag cacgtcagat
    35041 cgccgattgg ttaattggga tgaacggtag cccactgtat agtttactct tgcagcaaaa
    35101 aggcatacca ggaagttttt ctttaggtag agtccaaacc ccaacactct atatgattta
    35161 tcaattgcag gaaaagatta gaaacttcca aaaagaacca tattttgaag gaaaagccca
    35221 agtaatcgct caaaatggcg catttgatgc gaagcttgat ccaaatgaaa cccaagcgac
    35281 acaagaagca tttgaagcct atttaaaaga aaaaggtgtt caattaggaa aacagccagg
    35341 tacgatcctt caagtcgaaa cagagaaaaa aagtgcggct agcccacgtc ttttttcttt
    35401 atcgagcctt cagtctaaaa tgaatcaact catgaaagct agtgccaaag atactttgga
    35461 agccatgcaa gggttgtatg aaggaaaata tctaagctat ccgcgaacgg atacccctta
    35521 tattacggaa ggggaatatg cgtatctgtt ggatcactta gacgaataca agcatttttt
    35581 aaaagccgaa gcgattccga ctcctattca tacaccgaat agtcggtatg tgaataataa
    35641 gaaagtccag gaacattacg cgatcattcc tacaaaaacg gttatgacag cagcggcttt
    35701 tgaacaacta agtccactgc agcaggctat ttatgaacaa gtgttaaaaa caacggtggc
    35761 catgtttgcg gaaaagtata cctatgaaga aacaacgatc ttgacgcaag ttcagcagct
    35821 tcagttaaag gcaatcgaaa aggtgccgct agatctaggt tggaagaagt tatttggaaa
    35881 agagagcgac ggaaaagaga aggaagaaga gccgctactt cctaaagtga caaaaggaga
    35941 aatggtgacg gtggatctac aagttcttga aaaagaaacc aagccaccac agccttatac
    36001 cgaaggtacg ttgatcacgg cgatgaaaac agctgggaaa accgttgata gtgaagaagc
    36061 gcaatccata ttgaaagaag tggaaggaat cggtacagaa gcgacacggg cgaatattat
    36121 tgaaaccttg aaacaaaagg aatatatcaa ggtagagaaa aataagctcg tggtgacgaa
    36181 taaagggatt ttgctttgcc aagccgtgga aaaagagccg ctgcttacga gtgccgaaat
    36241 gaccgccaaa tgggaaagct acttgttaaa gatcggtgaa cgaaaaggaa cacaaaccac
    36301 ttttctagcc aatatccaaa aatttgtctc tcacttattg gaagtcgtac cagggcaaat
    36361 ccaatccact gattttggat cgacgttaca agaagtgaaa gcagccagtg aaaagcaaga
    36421 agccgcgcgt catttaggaa tttgtccaaa atgccaggaa caagaagtct tactctatca
    36481 aaaggtggca gcatgtacgt ctgaagcctg tgatttcaaa ctatggacaa cgattgccaa
    36541 aaagaaactt acagcgacac agctgaaaga gatcattcaa aatagccgaa caagccaacc
    36601 agtgaaaggg ttaaaaggtc agaagggttc gtttgaagca acgattgttt taaaagaaga
    36661 cttcactaca ggctttgaat tttctgaaaa gaaaaaaacg aacttcaaga aaagaacacg
    36721 acgcactaca aaataatgga gggttaatct tatgcgtaat acaacacaca aacaacaaga
    36781 aatcgaaaat caaaaagcca aaattcgttc agaacaggaa aaaatgcgtg ccagcaaacg
    36841 aagactgcag caattgaaga accagcagcg gattcaaaaa gaaatcgaat tagatcgata
    36901 aattcctttc ttgttaatat aaaactaaca tgttatagtt gtgttagttt tatattaact
    36961 ttaggggaag agtaatgaaa gacaaaatcc aatgtatttt tgataaacat aatggcaacc
    37021 tatccttgaa ggatgctaga agtgaaggat tatcgcctat gacgttagat cgattagccg
    37081 aaaaggataa aatagaaaag gtagcaccag gtttctatac cttaaaggat gcgttcgtgg
    37141 atgaattgta tctcgctcag agtatctatt ccagagggat tttttctcat gagactgcgc
    37201 tcgatctttt tcaagtagga acatatatcc ctaaaaagat caatatgatg tttcctaaag
    37261 gatacaatgt atcaaaggag aaattagatc agtatgccat tcaaccgcat tacactaata
    37321 aagaaaattt tgacctggga gtcacagaaa cagaaagctt ttacggcaat aaaattttag
    37381 tctatgattt agagcgaacg ttatgtgaca tgtggaatcc aagatacaaa gcaagcgtag
    37441 aggtaaaaca agaagcatta aaagaatata tgacaagtac cagtagaaat acaaataagc
    37501 taagaagata catggatatt ttaaaatcac caaaagaaat gactttgtat atgttgccac
    37561 tttattgaga ggagtaaaga tgaatgacac cgacacaatt taaagagaaa acaagaaatt
    37621 tcgcagcaga gaaacattta aacccacaaa ttgtccaaag atattatatg atggaaaaat
    37681 tattagaatg tattgttgaa tcgccttatc atgatgattt tgtattaaaa gggggatttc
    37741 tgattggatc aaaatacggg ttagaaaacc gttcaaccgt tgatattgat acgacttatc
    37801 gaaattcgaa actaacaaaa gaaaagttag aaactgtttt ttctgaatta acagctaatc
    37861 ctacaaaaga tggaattcgt tttgaattaa agggattaac agagacgagg gaagccgatt
    37921 attatccagg ttttcaagca aagtttattg cttatcttga aaatgcacgt gtacctttta
    37981 aattagatat tacttcaggt gattctatta ttccagcagc attgatgtat gaacacaaat
    38041 taatgtttga agataaaacg attcatattc cagcttatcc tacggaacaa attctagctg
    38101 aaaaattaca tgccacgttt agttttggaa aagataattc gcgcatgaaa gatttttatg
    38161 acctgtatat gattccgaaa ttagaacgta tcgatgagaa aaatttgtat aagagtgttc
    38221 aaggaacatt caaggaaaga aataatcaat cggtgtttaa gcatttgtat gatcaggaaa
    38281 tgcctcaatt ggtgaaagat gagggcttga gagaaaagtg gaaaagatac caacaagaaa
    38341 actattttgc caaagacatt tctttcgaat ctacactaac ttccgttgat tccctgatgc
    38401 aatcaattgt agagcaagag aaggcagaac gaaaacaaaa ttttaagaga tcacaacaaa
    38461 tgaatcaaga aatggagaga taaagatgat caataatgta actttagtag ggcgattaac
    38521 taaagatcca gatttacgtt ataccgcaag tggcacagca gtggcgactt tttccctagc
    38581 cgttaatcgt aatttcacga atcaaaacgg caatcgagaa gctgatttta tcaattgcgt
    38641 gatttggcgc aaaccagcag aaacgatggc gacattagct aaaaaaggca gcttgatcgg
    38701 cgttgtcgga cgaattcaaa cacggactta tgacaaccag caaggacaac gtgtgtatgt
    38761 gacagaagtt gtggccgata acttccaact attagaaagt aaagcagcga cagaaagccg
    38821 tatgcacgct gatcaatcgt ccagcagtcc aagccctacc acctttgaac aacgggatac
    38881 agcgacgcct aacaacaatg gattgaacgc ttcacagaat ccatttggtg gacaatcaat
    38941 cgatattagc gatgatgatc taccgttcta agtagcattt tctattggtt gcatttgcta
    39001 cggtttatgt tataatttag acaacaaaaa gaattttcaa tctataacca aaaaccacta
    39061 gctggcgggc tagtggcttt cttttacgtt tctattataa gaattaacgg gtaggcttac
    39121 tgtctttctt ggcaaattta caatcaagcc atttgcagat atagtgcgcg gctacttctg
    39181 ccatgattgc aaaaacaaaa tcaaaaagaa ttttcaaacc tataacctcc tccccttgcc
    39241 agattaggcc ggggtagcag acagcaagac tattatagca taattgaaat atccaaatga
    39301 ttggattttt gctataattt tagcgaggtg attgtgatga acaaatatgt tggtttgctt
    39361 gataaaatcc gagtaataaa aacgcaaccg ttattggttc gctttacttt acaaacgatt
    39421 catgaatcga ttaattgtgt agttgcagat attgaaatta tcgataaatt gctaattatg
    39481 gatgatggaa aatacaatat tgccgtcaca ggtcacttca ataaacgaaa tcagctagtt
    39541 attgctagca tgtatgttag aaatcccgat cattttacgc gatcgatggg catataaata
    39601 aaagaagagt tgtagtccta aatgaggatt gcagctcttt ttgttttaca tagaaacagg
    39661 aaaagacctt tttaggaaga cacaagtgcc ttctcaattg aaaaaccttt ctctcactcc
    39721 aaccgccacc gccgttcgag aagaaaggaa gtgaacgctg cacgttcact aagatatggt
    39781 gtcttgcaaa gcaagacaaa atagacaaaa cttcctctca ccaaaaggtt cgttcctgtt
    39841 cgttatctct ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg
    39901 acaaggacaa gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattt
    39961 attctggcca acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag
    40021 aggaggcaga atcaaacatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat
    40081 tattcccaaa ctatcatgca ccacatactg ttgaatgcga ttgtggagaa agagcgaaat
    40141 gtatcaaaag ctatcgtttg tatcaatgtc caacatgcgg gaaaaaatat accttgtctt
    40201 atggcgatta cattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cacaacacaa
    40261 attattgact gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa
    40321 agtagcagaa gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga
    40381 tgcaccgact atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca
    40441 agaaaacatg gaaacttatg aaatcgaata ttggttaacc aaattagaga actaaaaagg
    40501 agaaaaaata tggctcaaaa ttactatgac gaatttgtca aattaccttt ggataaaatg
    40561 gcacaaaaaa tggaggatat gacgttccta taccatgaaa cacgtgtacc caaaaaacat
    40621 tacaaggaaa aattgtcagt cgcagtggaa gaaatgattg aatcaggtgt cgaaatgaat
    40681 ctcattgcga cgtactatcg aacactggaa gaactgaaaa aacaaaatgg aaaatggttt
    40741 ttccaagcct tactatgctt ggaagtaggt gtcaaaccaa gcactatcaa accttccgaa
    40801 tatcaagcct tagaactgac ttatgcaaaa ttcgcacaga ttaagaaagc taaagcaatg
    40861 gctagcgact ggctagatac ttttgaaagt atcgaaaaaa atggtgcatt ttatacgatt
    40921 gaatcggagg agaaagataa tgaataaggt ggtttatcag ctaacaacag aagatgtttc
    40981 gcaattttta acaagcaaag aacacttgaa tgaagtaatc agacggattc aaaaagactt
    41041 tagttgtatg gaagaaatga agtactttat tcaaagagtg gaagaacagt tgtatatgga
    41101 aagcgaaaca agtcaaacga aggtcacagt cagccataat catttagacg tgtataaacg
    41161 tcgtcctgaa acggtaaaaa aaggaacaga gcttctacga ctagaaacag aaaaatacat
    41221 catgaatgtg tacctagaaa ggagtgagct ggtcgaaaac tttgtcagct acacgatttg
    41281 taggaaacac tattactcag aatcagaata ttattcaatt ttcgagagca tggaattaat
    41341 ggaagaagaa atggaagagc taaacagcaa aaatgcgacg gtagacgatt attaccttgt
    41401 atttactagg tttttgacgt gtgggacgga atctatcgtg ttaatgggaa tggattatga
    41461 actcgctgta cccgaagcat ttttgaggga atatgtagaa gaagtagata acccaggcga
    41521 cgactggtac acgactttaa ctgatttttt agacacctac acttacgacg atacagaaga
    41581 aatccaaaat gaacttgacc gtaaacgaat gccatatcaa cgatttgaaa ggaaaaaagg
    41641 taaataacca tttataccga aaagtgagga tgtgtgaaat aagaacaaaa aaccttgaaa
    41701 ttaagggaat ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt
    41761 gcgaaataag cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa
    41821 atcattcctc tattgttcgt actgtttgtt ggcgagatac ttatgcgtca tgctgcagct
    41881 gtacatttaa acttcgtagt attcttagga atactggtat tttgtttgat cttttggcga
    41941 tttgtattag cccttgtgag tctactattc aagatgattg cagccatatt tttcataggg
    42001 ttatttcgat gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc
    42061 gtgacattag atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa
    42121 agtgaatcta agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga
    42181 tttgatatac cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata
    42241 gcacttaatt gttcctacta tttagaatat tttctatgtc ctttttattc c
//
LOCUS       DAZKCH010000014        41035 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000014 DAZKCH010000000
VERSION     DAZKCH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.014"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(38..1189)
                     /locus_tag="ACG84X_000800"
     CDS             complement(38..1189)
                     /locus_tag="ACG84X_000800"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFP9126697.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="ACG84X_000801"
     CDS             complement(1202..1639)
                     /locus_tag="ACG84X_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9126698.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGGVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="ACG84X_000802"
     CDS             complement(1654..3420)
                     /locus_tag="ACG84X_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFP9126699.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="ACG84X_000803"
     CDS             3684..4361
                     /locus_tag="ACG84X_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFP9126700.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="ACG84X_000804"
     CDS             4364..5491
                     /locus_tag="ACG84X_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126701.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="ACG84X_000805"
     CDS             complement(5691..6131)
                     /locus_tag="ACG84X_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9126702.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="ACG84X_000806"
     CDS             complement(6142..8175)
                     /locus_tag="ACG84X_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFP9126703.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="ACG84X_000807"
     CDS             complement(8177..9880)
                     /locus_tag="ACG84X_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9126704.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="ACG84X_000808"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="ACG84X_000808"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFP9126705.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="ACG84X_000809"
     CDS             complement(10963..11988)
                     /locus_tag="ACG84X_000809"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFP9126706.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKTVLPK"
     gene            complement(12197..13066)
                     /locus_tag="ACG84X_000810"
     CDS             complement(12197..13066)
                     /locus_tag="ACG84X_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9126707.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="ACG84X_000811"
     CDS             complement(13525..15417)
                     /locus_tag="ACG84X_000811"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126708.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="ACG84X_000812"
     CDS             complement(15414..17141)
                     /locus_tag="ACG84X_000812"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126709.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="ACG84X_000813"
     CDS             complement(17157..17807)
                     /locus_tag="ACG84X_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFP9126710.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="ACG84X_000814"
     CDS             18011..18307
                     /locus_tag="ACG84X_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFP9126711.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="ACG84X_000815"
     CDS             18479..19099
                     /locus_tag="ACG84X_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFP9126712.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="ACG84X_000816"
     CDS             complement(19191..20357)
                     /locus_tag="ACG84X_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9126713.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="ACG84X_000817"
     CDS             complement(20369..20722)
                     /locus_tag="ACG84X_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFP9126714.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="ACG84X_000818"
     CDS             20850..21872
                     /locus_tag="ACG84X_000818"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFP9126715.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="ACG84X_000819"
     CDS             21891..22052
                     /locus_tag="ACG84X_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126716.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="ACG84X_000820"
     CDS             complement(22311..22745)
                     /locus_tag="ACG84X_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126717.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="ACG84X_000821"
     CDS             complement(22855..24714)
                     /locus_tag="ACG84X_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFP9126718.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            24715..24855
                     /locus_tag="ACG84X_000822"
     CDS             24715..24855
                     /locus_tag="ACG84X_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFP9126719.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(24832..25992)
                     /locus_tag="ACG84X_000823"
     CDS             complement(24832..25992)
                     /locus_tag="ACG84X_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFP9126720.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="ACG84X_000824"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="ACG84X_000824"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFP9126721.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="ACG84X_000825"
     CDS             complement(27739..28437)
                     /locus_tag="ACG84X_000825"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFP9126722.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="ACG84X_000826"
     CDS             complement(28394..30055)
                     /locus_tag="ACG84X_000826"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFP9126723.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="ACG84X_000827"
     CDS             30273..31673
                     /locus_tag="ACG84X_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFP9126724.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="ACG84X_000828"
     CDS             complement(31925..33004)
                     /locus_tag="ACG84X_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9126725.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="ACG84X_000829"
     CDS             complement(33090..34049)
                     /locus_tag="ACG84X_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFP9126726.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="ACG84X_000830"
     CDS             complement(34061..35572)
                     /locus_tag="ACG84X_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFP9126727.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="ACG84X_000831"
     CDS             complement(35594..36157)
                     /locus_tag="ACG84X_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFP9126728.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="ACG84X_000832"
     CDS             complement(36163..37026)
                     /locus_tag="ACG84X_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9126729.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="ACG84X_000833"
     CDS             complement(37040..37936)
                     /locus_tag="ACG84X_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9126730.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="ACG84X_000834"
     CDS             complement(38111..39400)
                     /locus_tag="ACG84X_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9126731.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="ACG84X_000835"
     CDS             complement(39372..40889)
                     /locus_tag="ACG84X_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFP9126732.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
BASE COUNT        11839 a         8591 c         7097 g        13508 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgcc ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgt
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggctgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccg tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcggttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agtgttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcatt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcataggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatattt cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaacccgtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaaattta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactccc tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacgttt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt gtcaataata taaatgttaa acttacttat tttttatcga
    40981 ttttaattaa ccaaaatatt aataatgatt aaaacaaata atttaatata acttt
//
LOCUS       DAZKCH010000015        38566 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000015 DAZKCH010000000
VERSION     DAZKCH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.015"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..328)
                     /locus_tag="ACG84X_000836"
     CDS             complement(26..328)
                     /locus_tag="ACG84X_000836"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9126733.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="ACG84X_000837"
     CDS             complement(353..2446)
                     /locus_tag="ACG84X_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFP9126734.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="ACG84X_000838"
     CDS             complement(2935..3699)
                     /locus_tag="ACG84X_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFP9126735.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="ACG84X_000839"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="ACG84X_000839"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFP9126736.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="ACG84X_000840"
     CDS             complement(4704..5780)
                     /locus_tag="ACG84X_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFP9126737.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="ACG84X_000841"
     CDS             complement(5804..6397)
                     /locus_tag="ACG84X_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFP9126738.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="ACG84X_000842"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="ACG84X_000842"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFP9126739.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="ACG84X_000843"
     CDS             complement(8067..8366)
                     /locus_tag="ACG84X_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFP9126740.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="ACG84X_000844"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="ACG84X_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HFP9126741.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="ACG84X_000845"
     CDS             complement(10121..11032)
                     /locus_tag="ACG84X_000845"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFP9126742.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="ACG84X_000846"
     CDS             11152..12009
                     /locus_tag="ACG84X_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9126743.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="ACG84X_000847"
     CDS             complement(12196..12558)
                     /locus_tag="ACG84X_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFP9126744.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(12747..12929)
                     /locus_tag="ACG84X_000848"
     CDS             complement(12747..12929)
                     /locus_tag="ACG84X_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126745.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            12904..14343
                     /locus_tag="ACG84X_000849"
     CDS             12904..14343
                     /locus_tag="ACG84X_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126746.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14350..16902)
                     /locus_tag="ACG84X_000850"
     CDS             complement(14350..16902)
                     /locus_tag="ACG84X_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFP9126747.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17016..18347)
                     /locus_tag="ACG84X_000851"
     CDS             complement(17016..18347)
                     /locus_tag="ACG84X_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9126748.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18313..19791)
                     /locus_tag="ACG84X_000852"
     CDS             complement(18313..19791)
                     /locus_tag="ACG84X_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9126749.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="ACG84X_000853"
     CDS             complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="ACG84X_000853"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFP9126750.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22401..23828
                     /locus_tag="ACG84X_000854"
     CDS             22401..23828
                     /locus_tag="ACG84X_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126751.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23920..24285)
                     /locus_tag="ACG84X_000855"
     CDS             complement(23920..24285)
                     /locus_tag="ACG84X_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFP9126752.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24282..24647)
                     /locus_tag="ACG84X_000856"
     CDS             complement(24282..24647)
                     /locus_tag="ACG84X_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFP9126753.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24839..25087)
                     /locus_tag="ACG84X_000857"
     CDS             complement(24839..25087)
                     /locus_tag="ACG84X_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126754.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25086..25214
                     /locus_tag="ACG84X_000858"
     CDS             25086..25214
                     /locus_tag="ACG84X_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFP9126755.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25271..26965
                     /locus_tag="ACG84X_000859"
     CDS             25271..26965
                     /locus_tag="ACG84X_000859"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFP9126756.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            27065..27238
                     /locus_tag="ACG84X_000860"
     CDS             27065..27238
                     /locus_tag="ACG84X_000860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126757.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            27616..28749
                     /locus_tag="ACG84X_000861"
     CDS             27616..28749
                     /locus_tag="ACG84X_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFP9126758.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28780..29100
                     /locus_tag="ACG84X_000862"
     CDS             28780..29100
                     /locus_tag="ACG84X_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFP9126759.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29129..29593)
                     /locus_tag="ACG84X_000863"
     CDS             complement(29129..29593)
                     /locus_tag="ACG84X_000863"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9126760.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29725..30978)
                     /locus_tag="ACG84X_000864"
     CDS             complement(29725..30978)
                     /locus_tag="ACG84X_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9126761.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(31007..31324)
                     /locus_tag="ACG84X_000865"
     CDS             complement(31007..31324)
                     /locus_tag="ACG84X_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFP9126762.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(31350..31670)
                     /locus_tag="ACG84X_000866"
     CDS             complement(31350..31670)
                     /locus_tag="ACG84X_000866"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9126763.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(32134..33549)
                     /locus_tag="ACG84X_000867"
     CDS             complement(32134..33549)
                     /locus_tag="ACG84X_000867"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9126764.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(33566..34882)
                     /locus_tag="ACG84X_000868"
     CDS             complement(33566..34882)
                     /locus_tag="ACG84X_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9126765.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(35032..35730)
                     /locus_tag="ACG84X_000869"
     CDS             complement(35032..35730)
                     /locus_tag="ACG84X_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFP9126766.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(36019..37008)
                     /locus_tag="ACG84X_000870"
     CDS             complement(36019..37008)
                     /locus_tag="ACG84X_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFP9126767.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(37088..37921)
                     /gene="msrA"
                     /locus_tag="ACG84X_000871"
     CDS             complement(37088..37921)
                     /gene="msrA"
                     /locus_tag="ACG84X_000871"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFP9126768.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(38096..>38566)
                     /locus_tag="ACG84X_000872"
     CDS             complement(38096..>38566)
                     /locus_tag="ACG84X_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126769.1"
                     /translation="KNFNQKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLEN
                     KEHIIKHEAKIGSQWVNLPYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPV
                     KEQVNANGLVQISGVKGVADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
BASE COUNT        11590 a         8018 c         6558 g        12400 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
    14341 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
    14401 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
    14461 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
    14521 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
    14581 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
    14641 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
    14701 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
    14761 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
    14821 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
    14881 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
    14941 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
    15001 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
    15061 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
    15121 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    15181 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
    15241 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
    15301 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
    15361 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
    15421 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
    15481 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
    15541 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
    15601 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
    15661 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
    15721 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
    15781 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
    15841 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
    15901 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    15961 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
    16021 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
    16081 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
    16141 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
    16201 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
    16261 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    16321 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
    16381 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
    16441 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
    16501 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
    16561 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
    16621 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
    16681 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    16741 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
    16801 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
    16861 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    16921 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    16981 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
    17041 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    17101 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    17161 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    17221 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    17281 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
    17341 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    17401 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    17461 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
    17521 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    17581 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
    17641 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
    17701 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
    17761 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
    17821 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    17881 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    17941 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    18001 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    18061 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    18121 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
    18181 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    18241 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    18301 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    18361 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    18421 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    18481 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    18541 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    18601 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    18661 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    18721 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    18781 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    18841 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    18901 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    18961 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    19021 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    19081 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
    19141 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    19201 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    19261 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    19321 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    19381 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    19441 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
    19501 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    19561 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
    19621 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    19681 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    19741 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    19801 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    19861 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    19921 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    19981 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    20041 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    20101 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
    20161 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    20221 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    20281 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    20341 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    20401 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    20461 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    20521 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    20581 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    20641 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    20701 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    20761 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    20821 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    20881 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    20941 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    21001 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    21061 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
    21121 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    21181 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    21241 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    21301 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    21361 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
    21421 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
    21481 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    21541 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    21601 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    21661 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    21721 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    21781 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    21841 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    21901 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    21961 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    22021 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
    22081 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
    22141 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
    22201 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
    22261 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
    22321 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
    22381 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
    22441 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
    22501 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
    22561 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
    22621 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
    22681 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
    22741 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
    22801 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
    22861 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
    22921 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
    22981 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
    23041 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
    23101 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
    23161 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
    23221 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
    23281 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
    23341 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
    23401 tttatctttt aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
    23461 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
    23521 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
    23581 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
    23641 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
    23701 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
    23761 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
    23821 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
    23881 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
    23941 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
    24001 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
    24061 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
    24121 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
    24181 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
    24241 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
    24301 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
    24361 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
    24421 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
    24481 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
    24541 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
    24601 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
    24661 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
    24721 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
    24781 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
    24841 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
    24901 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    24961 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    25021 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    25081 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    25141 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    25201 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
    25261 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
    25321 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    25381 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    25441 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    25501 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    25561 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    25621 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    25681 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    25741 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    25801 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    25861 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    25921 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    25981 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    26041 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
    26101 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    26161 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    26221 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    26281 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    26341 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    26401 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctattgt
    26461 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
    26521 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    26581 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
    26641 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
    26701 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
    26761 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    26821 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    26881 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    26941 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
    27001 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    27061 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaagctg ccctgcatca
    27121 agtaataaga gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt
    27181 accgcagatg caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt
    27241 tcgagtatga agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt
    27301 aataccgaga aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt
    27361 gaaaacaact attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac
    27421 aactatttca atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa
    27481 tacataagac tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa
    27541 gatctccttt aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg
    27601 aaaggagcat ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga
    27661 aacgtagatg atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca
    27721 gccatttgcg gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg
    27781 tatgttgtag gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca
    27841 ttgaaaaaag ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc
    27901 tgcctgaatc acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg
    27961 cttttcggat ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga
    28021 gttccttatg cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa
    28081 gttttatttc tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta
    28141 aaaaaaggcg atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa
    28201 ttcgctgtta tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta
    28261 gataaagcgg ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct
    28321 ggaacagaat tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga
    28381 atggacggat tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc
    28441 acaatctctc cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta
    28501 actggtgttt atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat
    28561 atcgctgtca agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg
    28621 attgcagaag gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa
    28681 gcagcacaag catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg
    28741 aaaccttgaa ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat
    28801 acccatgaga tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc
    28861 ttctatttcc aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt
    28921 ttctatattt ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat
    28981 ttttatttgg ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac
    29041 atttttattt acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga
    29101 gaatttttca aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag
    29161 cggtcgtccc actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa
    29221 acgtggtatg atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc
    29281 tgatttccgc taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca
    29341 gggcacaaag atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg
    29401 ctcctccgac gatggtttct ttttcatcta agaccacata ccattgagga atactttcct
    29461 tattagcgat tccagtacga atactttcct catacacaac agcaggaact ccccattttg
    29521 atgaaaacca attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt
    29581 tatatgtaac caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag
    29641 tctttatgaa aattagcaat gacaacaata gtgatgtaaa aaaaaaaacg gaaaacaatc
    29701 acttgttctc cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat
    29761 cgtagctacc ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc
    29821 tagtacacca cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac
    29881 ccatggaggc ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac
    29941 actaactaag accattggtg tcaaaataaa tggaatgaac atgatcgggt tcaacacgat
    30001 aggtaaccca aacatcgttg gttcattaat attgaagaca cctggcgcaa tcgacaagtt
    30061 tgttacaacc atatatggtt tgtttttacg tcctactaaa taaatagcta acagtaaacc
    30121 taaagttgca cctgttcctc ctaagttgac aaagctgtca aagaaaggtt tgttcacgat
    30181 aaacggtgcg ctatgtccag ctgcgattgc attaacgttt gcttcaatgg ctggcgcatt
    30241 gattgtttgc atcaaaggat cgaccatatt cgctccgtgt aaaccaaaga accataagaa
    30301 tggtgtgata aatgcaagca gtaaggcaga tggataagag tttgcaagtc ccataaatgg
    30361 ttcttggacc actgtataga aagaacctac gatatcatca acaccgaatg cagcaaaaat
    30421 tgcagcaact aaagcaaacg cagagatagt gatcattgct ggtagtaatg aagcaaatgc
    30481 ttttgcaact gccggtggca caccatcagg cattttgatg atcaattttt catttccgct
    30541 taaacgtaca aagatttctg ttgaaataat cccaacaata atagcaataa acaaaccgtt
    30601 tgagctcata cctaatgctc cgcctaaagc gaagaaagag cctaaagaaa tcacacctgc
    30661 ggaaacaccg tcttttcggt agccgttagc taaatgataa gcaagcaaga aagcaatcaa
    30721 gacagaaaga atggcaaatg taccgttcca agcagcagcc ccgaatcctt tccatgattc
    30781 accaccaaaa attgagttca tcaattcttg gaacccggga atcggtaagt tattgatcat
    30841 tactgctaat gctcctaaga tcattaacgg catactcacc ataaatgagt cccgaatcgc
    30901 aactaaatgc cgttgtgcac caatttttga tgctacaggt ataaaatgtt tctccataaa
    30961 tgcaacaaat ttatccataa atcttccctc ttttctttac tgtagattac gcgttcaatc
    31021 gacgatacag atcaatgatc tcttttgcta aatctgtaaa agctatagat gtcatcagat
    31081 gatcttgact gtggaccgtc aaaagcgtga cttcaacgtg atttccttgt gcttcttgtg
    31141 tcagcatctc tgtttgagag tgatgtgctt ggactaaaga ttcctctgca tctttgattt
    31201 tttcatctgc taaagtgaaa tcaccttttt tcgcagcagc aatcgcttcc attgcatcgc
    31261 tttttgcatt tccgccaaac atgatcagac ccatgatggc ttctagattt ttttgatctt
    31321 ccatttattg tatcctccga taatttttat tatttgttta ttagtttttc tgcttggtcg
    31381 agtacttttt caccattcat catgccatag tcagccatat tgattacatc taaaggaatg
    31441 cctttaggtg ctagcttttc agcaaattga ttttgcataa agcgtacttg cggtcctaaa
    31501 agtaaaacgt ctacattttt agattctagt tgattatccg catctgaagc agatacagca
    31561 aagatgtctg cttccattcc ttttgcttct gctgcctttt gcatttttgt gactaggaga
    31621 cttgtactca ttccagctga acatacaagc atgattgttt tcttttccat tttaaacacg
    31681 ttcctttcta tacttacact tgtatataag caagtagcgt gccaacttta aaagcgcttt
    31741 aaaaagttga tatcatcaca tttaaggtct ataccaagtt gcatacacac taaaaaagaa
    31801 agcgcacact aaacacacaa attaattttt attacctttt ttcttttaac gtgcacaaaa
    31861 aaagttgtga cacaaaactt gtcacaactt ttttcaaata aacggtattc aaaagcttgc
    31921 atctgcggta ataagtccaa ccaagttaaa aacataagat gttgttttta ctttgctatt
    31981 cttattactt gatgcaggac agctttttca caacctctca ataaacggtg ttcaatcagc
    32041 tgaccctggg tattagctca aaacgctgga ttcacaacct cttttatttc aaataaccag
    32101 taaatacaat gaacatctac aaaaaacttc tatttattta tagatttcgt caggcaaatc
    32161 caattctctc ttatcaatca aagtctgata ccacgaagca gattttttca atgttctgct
    32221 tcgttcatcg ttcaattcga ttcgaactaa tccatatcga ttcttaaatg cattcattgg
    32281 tgacacacag tcagtgaatg cccataacat atagccttcg caatttgcgc cttcttctgt
    32341 tgctttgatc aagtaatgca aatgctgtcc gataaattcg atacggtaat catcttgcac
    32401 gattcctttc tcatccatat actgttcttc atattctctt cccataccgt tttctgttat
    32461 cagccaaggg atattatgat aattttcttt tagatacatg gctatatcat acatgatttt
    32521 cggatagatt tcccatcccc tggaattatt cattttcttc ccaggtaaat caaagacttc
    32581 ataatatcgt tcaggatgga aaggtgtctc ttcattccat tgataacgag gggcgcgaac
    32641 gcgtttagga taatattgat tgattccaag gaaatctact gtatgatgct gaatcgtttc
    32701 taaatcctct gttgcaggat cgaaataaat cgattgtttt tgacacaact ccaggaactc
    32761 ttctgtgtag tatcctttta ccatcggatc aaaaaatact cgattataaa acaaatcata
    32821 catataagca gctttttggt cttctggaga attggatcga gcatagacca tttcaggatt
    32881 taaaatacag ccaatccttc caccataatt tccgctgcgg taaatctcta ctgctttagc
    32941 cgttgctaaa actttatgat aattccacat catccacttt tttgtgtttt gttcatgcgg
    33001 ccagcgaaca gcatccaaat agcaacgcgt ttggggaacg attggttcgt tgaatgtaaa
    33061 ccagtttttt accctatcac cgtaacgatc aaaggcaatt tgagcatact tagcataaaa
    33121 atcaactact tttcttgaag accagccatc atatttttcc aaaagaaaag ctgggacttc
    33181 ataatgttcc aaacaaatca tcggttctac gtctgcttcg atcaaagagt cgatcatttc
    33241 acttatatgc tgagcatatt cttcatctac tatacagttc tcataatcag taaaaaaacg
    33301 agcccaattg atagaagtcc gataatgtgt cagatggatg gatttcatca gatccacatc
    33361 ctgctggtat tgttccataa aattagttgc tacggctggg ccatacccat tatgccaaac
    33421 aaaatgttca tttttatacc agctatctat aaacgaatcc tgtccttctt tttttccttt
    33481 ccaaccttcc gtttgccaag cagaagatgc agcaccaaga ataaaatttt ttggaatagt
    33541 aattttcatg atttcctcct gttttttaga tcccatcatt ttccacacga tttgctactt
    33601 ttacaaatgg cagatagatc aaaatagaaa caataataca aacaagttgc gtaataactg
    33661 caccgatatt tcctgctgtt gccagataag cattgacgat cggcggcatt ggccaaggga
    33721 ccattacaac tgctttcgcc gcaaatccta aagcggttgc aaaataacca atcgttccag
    33781 tgataagagg cgttaagata aacggaatag ctaaaattgg attcagcatg atcggcatac
    33841 caaaaataac tggttcattg atgttgaaga tcccaggagc aagggataac ttggtgattt
    33901 gtttcatatc ttcccgtttt ccaactaaca atactgcaat cagtaaaccg atcgtgactc
    33961 cagacccgcc catactcata tacatatccc aaaatggcat agtaataatg ttcggtactt
    34021 cttttccagc ttcaaaagct tccgtattta cagcaattgc cgctaaaagc aacggttccc
    34081 gtatcggctt caccatttga tttccatgga taccaatcac ccaaaagact tgcgcaataa
    34141 acatcaatag caaaataccc ggtaaccctt gtacgacacc ttctaatggg cgttgtacga
    34201 cattgtaaat gatatcataa aggtacattc ctgtaagttc tttgatgata aatcccgcag
    34261 ccgcgatacc cgatacagtc agaatcgtcg ggaataaagc agaaaaacta gcagaaacat
    34321 tcgttggcac ggtatcaggc attctcagct gtagtttctt ctgtttcctc aaccagcaat
    34381 aaagttcaat agaaaggatg gagaccaaca ttcccaaaaa taaccctttc gtatctgtat
    34441 attgtttagc caatacgttt tctactataa cagtctgatt ttcattcact aattcataaa
    34501 cagttggatt aacagataaa taagacatca ctgcgatgat accagggaat acaccatcca
    34561 ctttattcag cttggctaat tcgatcccta tcagaaaaac agcatagatg gtcaagaaac
    34621 ttagtgtgac atagctgatg gcagatgcga taggctttaa ttcttctaaa aaacgcaaga
    34681 aacttatctg tgctaagcca ttttccgagt caaagaccat tgctgaaaac aatgtgccaa
    34741 aagcacccgt aataattacc ggaatcaatg cagcaaatgc gttttttatc accatgatat
    34801 accttaaatt attgattctc gttgccacgt tccctaaaac attggctaat ttatccataa
    34861 aactcattcc agatcccctc attcctgctt cttctccttg acgtcatctc tttttgtcta
    34921 ttagtcagcg cttacatttc gatgaacaga aactatttac tcctcttttt taccaaatat
    34981 aaaacaaaaa ttcatctgat gtatttatca taaaatacat cagatgaact gtcaattagt
    35041 ttctttttct cctattattt tctgtaattc tctccgattt attgccatat ggacagtcat
    35101 tgcatcaaac gcagcaagtg cattccgcct ttcgatggcc tgaacgatct ctgtatgaat
    35161 atcgatcgtc tcgattttca gatgctggat atcataattt ttattaaaca aagcaattga
    35221 ttcattaatg attgggataa tatgcagcaa ggctacgttt ccgctagctt ctgcaatcat
    35281 cgtatgaaaa tcgatgtcta attgaacatg ttcttgtgtg ccttctcgaa aagaagtttc
    35341 aatcttttgc gttaattttt tcatttggac gatttgattc ttcgttgcat attccgctgc
    35401 caaacctgcc atcttaggct ccaataaata tctcagttca aataagtctc gtatcatccg
    35461 atcctgatct tcaatcaaag aaaaaccgag tgggtcattg gcaatccctc gcttatcact
    35521 gacaaatgtc cccgctcctt gccgaacttc aaggatattc ctggaagcta gagcccgcac
    35581 agcttctcgc accgtgcttc gccccacctc taaataatcg gacaattcat attcattcgg
    35641 cagtttatct cctacttgca actgcatttc ctttaaatat ctaaggatct tgtcagtagt
    35701 tacttctact agggttttat tttcttccaa accacatacc tccttttcat ctgatgtatt
    35761 ttttcgtaat tattataaca cgtttgaatc atctgatgat tttttgtata caaaattgat
    35821 taatccgttc atagacatac aaacgaagaa gatatttacc ataaaaaaga ctaggataaa
    35881 attcactcct agccttcgat catttttatt ttgaacgaca aaaaatatga tgttcaataa
    35941 cagacgatct tcattcgatt cttgatgtca tcttttgttt tttttaatat atggataaaa
    36001 agtttgatta catcgtttct attctagaat ttggtcgatt ctcaattctt cttctggtga
    36061 gaaatctaaa ttatccatca ttcgaacact ttcttgtaac tgacttaacc gacttgctcc
    36121 gaccagtaca cttgtaacag atttttgtcg caaattccat gcaagggcca tttgcgctaa
    36181 tgattgtcct cgtgatacgg cgattgtttg cagtgctttg attttttcca gagttgatcc
    36241 aacttgttct tctgaaagga atggtatttc cttacgatgt gctctagaat cttcaggaat
    36301 accatgtaga taacgatttg tcagcaaccc ttgagcaagc ggactgaacg tgattgcccc
    36361 tagcccttct tcttctaata ctggagatag atcgtcttct agtagtgcac gagaaaacat
    36421 attgtagcgc atctgatgaa taatgaacgg tgcttccttt ctttttaaaa tttcagtcat
    36481 tttttttgta tcttctccat tatagttgga tataccaata tataatgctt ttccttgtct
    36541 tacaagttgc atcaaagctt ctgctgtttc ttccaaaggt gtatcagggt ctgggcgatg
    36601 atgatagaag atgtcaacat aatctagccc cattctttgg agactttggt cacaacttga
    36661 aatgatggat ttacgagagc cccattcccc atatggccct tcccacatat gataacctgc
    36721 tttgctagaa ataatcagtt catcacggta ggcttgaaaa tcttctctaa aaatacgccc
    36781 aaagtttttc tctgcagctc cagcagggcc tccataatta ttcgcaaggt cgaaatgggt
    36841 aattcccatg tcgaatgcgc ctcttaaaat ctctctttga ttatggatag gatcataatc
    36901 accaaaattt tgccataatc cgagagataa aatcggtaat ttcaaacctg aatgaccgga
    36961 tttacgatat tccatttttt cataacgtgc actatctgca atatacaatt tttctcctcc
    37021 tcatcaaatc tttttaaaac gctttctttt ttctattttt agtttactac attttaaaga
    37081 aaaggagtta atcaaaatga ttttttcgta tatttttttg ccatttgttt tttactcgtt
    37141 gatagatcag aaattgatta cgtgcttgct ggattttttt ataacgtttc ggttgttttt
    37201 tgtaaaattg ctgatgatag ttttctgctg gccaaaacgt accggctggt tcgatttttg
    37261 tgacgattgg ttggtggaaa gttcctgaac tgtctagttt ctgttttgat tgttccgcta
    37321 attctttttg tcgttcgact tgataaaaaa tcactggacg atattgcttc cctctatctt
    37381 gaaattgtcc aaatgtatct gtgggatcag taatttgcca atagattgtc agcaactcgc
    37441 tataacttat ttctcttgtg tcataaatga tctccacagc ttccacatga cctgtgtaac
    37501 caccacttac ttgatcataa tttggttttt caacatgtcc gcccgtgtat cctgacaaaa
    37561 cagataggat cccttttttc gattcaaacg gctcgaccat acaccagaaa catccccctg
    37621 caaatactgc acgttcttga tagtcagcat cttgcatggc atgcttggaa aagtcatatt
    37681 tttgctcctt atcaaatcct tccgtaatca ataaataaaa gtccattaca tcaggcgtca
    37741 gattcattcg gatagctaat ggacgtagtg ttgcttctag ttttgataac tgttctttaa
    37801 cggatatatt ttctcttatg tcattctttg tctgaatcaa tacttttcgt tcccaatctc
    37861 gtgtattcgg attcaaaatc agattataaa gtgtttgaat gaatatttgt tcctcatcca
    37921 tagattctcc tcctttccga agaagacaag ctagtgactt tagctgtaat ttatcataaa
    37981 gtgaggaaat aagcgattac ttcatccccc tacagatttt tcgtataaaa aagagagaat
    38041 ccttatcgac agattctcct ttttaatcaa tttattttat aaatgaaaag ttaatttacc
    38101 ttttatggaa aactatttta aaaaataaac ataaatatgc agttaatgta acaagataag
    38161 aaataatagt cgttactgta taacttgtgc ttactttaat atcagcaact cctttgactc
    38221 cgcttatttg taccaatcca ttagcattca cctgctcctt tacaggttga tgatttattt
    38281 ctacattcgt tcctaaataa gcatatacag gaagtgtgat tacttggctc ttctcattag
    38341 ttactctata tatgatagaa ctaccagttg ttttataagg aaggtttacc cattgactgc
    38401 caatctttgc ttcgtgtttt attatatgct ccttattctc caatgaagcg ataggagaat
    38461 aatcatataa aaaataatcc attcctttag tggtatacgc ctctactgtt tctttgttta
    38521 caacaatatg tcccggctga gaaattattt tttgattgaa attttt
//
LOCUS       DAZKCH010000016        38314 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000016 DAZKCH010000000
VERSION     DAZKCH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.016"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..182)
                     /locus_tag="ACG84X_000873"
     CDS             complement(<1..182)
                     /locus_tag="ACG84X_000873"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9126770.1"
                     /translation="METRDYIITHQKLIESGLSHFEKEGFQQTKIRQLCLTAGVTTGA
                     FYKHFTSKEALFEEII"
     gene            complement(474..707)
                     /locus_tag="ACG84X_000874"
     CDS             complement(474..707)
                     /locus_tag="ACG84X_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFP9126771.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(722..1672)
                     /locus_tag="ACG84X_000875"
     CDS             complement(722..1672)
                     /locus_tag="ACG84X_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFP9126772.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(1669..2511)
                     /locus_tag="ACG84X_000876"
     CDS             complement(1669..2511)
                     /locus_tag="ACG84X_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFP9126773.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(2513..3232)
                     /locus_tag="ACG84X_000877"
     CDS             complement(2513..3232)
                     /locus_tag="ACG84X_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFP9126774.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            3780..4070
                     /locus_tag="ACG84X_000878"
     CDS             3780..4070
                     /locus_tag="ACG84X_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126775.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNT"
     gene            4142..5368
                     /locus_tag="ACG84X_000879"
     CDS             4142..5368
                     /locus_tag="ACG84X_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9126776.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(5456..5848)
                     /gene="rpsI"
                     /locus_tag="ACG84X_000880"
     CDS             complement(5456..5848)
                     /gene="rpsI"
                     /locus_tag="ACG84X_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFP9126777.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(5864..6292)
                     /gene="rplM"
                     /locus_tag="ACG84X_000881"
     CDS             complement(5864..6292)
                     /gene="rplM"
                     /locus_tag="ACG84X_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFP9126778.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(6826..7293)
                     /locus_tag="ACG84X_000882"
     CDS             complement(6826..7293)
                     /locus_tag="ACG84X_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFP9126779.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(7413..8951)
                     /locus_tag="ACG84X_000883"
     CDS             complement(7413..8951)
                     /locus_tag="ACG84X_000883"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFP9126780.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            9031..9717
                     /locus_tag="ACG84X_000884"
     CDS             9031..9717
                     /locus_tag="ACG84X_000884"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFP9126781.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(9918..10445)
                     /gene="msrA"
                     /locus_tag="ACG84X_000885"
     CDS             complement(9918..10445)
                     /gene="msrA"
                     /locus_tag="ACG84X_000885"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFP9126782.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(10529..11206)
                     /gene="pgmB"
                     /locus_tag="ACG84X_000886"
     CDS             complement(10529..11206)
                     /gene="pgmB"
                     /locus_tag="ACG84X_000886"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFP9126783.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(11203..12333)
                     /locus_tag="ACG84X_000887"
     CDS             complement(11203..12333)
                     /locus_tag="ACG84X_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFP9126784.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(12333..14516)
                     /locus_tag="ACG84X_000888"
     CDS             complement(12333..14516)
                     /locus_tag="ACG84X_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFP9126785.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(14513..15538)
                     /locus_tag="ACG84X_000889"
     CDS             complement(14513..15538)
                     /locus_tag="ACG84X_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9126786.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(15583..16410)
                     /locus_tag="ACG84X_000890"
     CDS             complement(15583..16410)
                     /locus_tag="ACG84X_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFP9126787.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(16407..17474)
                     /locus_tag="ACG84X_000891"
     CDS             complement(16407..17474)
                     /locus_tag="ACG84X_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFP9126788.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(17500..18336)
                     /locus_tag="ACG84X_000892"
     CDS             complement(17500..18336)
                     /locus_tag="ACG84X_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9126789.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(18333..19202)
                     /locus_tag="ACG84X_000893"
     CDS             complement(18333..19202)
                     /locus_tag="ACG84X_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9126790.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(19272..20555)
                     /locus_tag="ACG84X_000894"
     CDS             complement(19272..20555)
                     /locus_tag="ACG84X_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9126791.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(20569..22254)
                     /locus_tag="ACG84X_000895"
     CDS             complement(20569..22254)
                     /locus_tag="ACG84X_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFP9126792.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            22529..23554
                     /locus_tag="ACG84X_000896"
     CDS             22529..23554
                     /locus_tag="ACG84X_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9126793.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(24149..27802)
                     /gene="rpoC"
                     /locus_tag="ACG84X_000897"
     CDS             complement(24149..27802)
                     /gene="rpoC"
                     /locus_tag="ACG84X_000897"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFP9126794.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(27881..31498)
                     /gene="rpoB"
                     /locus_tag="ACG84X_000898"
     CDS             complement(27881..31498)
                     /gene="rpoB"
                     /locus_tag="ACG84X_000898"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFP9126795.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            32226..33194
                     /locus_tag="ACG84X_000899"
     CDS             32226..33194
                     /locus_tag="ACG84X_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9126796.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            33212..34117
                     /locus_tag="ACG84X_000900"
     CDS             33212..34117
                     /locus_tag="ACG84X_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126797.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            34114..34920
                     /locus_tag="ACG84X_000901"
     CDS             34114..34920
                     /locus_tag="ACG84X_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126798.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            35077..36045
                     /locus_tag="ACG84X_000902"
     CDS             35077..36045
                     /locus_tag="ACG84X_000902"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFP9126799.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(36362..36886)
                     /locus_tag="ACG84X_000903"
     CDS             complement(36362..36886)
                     /locus_tag="ACG84X_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFP9126800.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            37173..>38314
                     /gene="scm"
                     /locus_tag="ACG84X_000904"
     CDS             37173..>38314
                     /gene="scm"
                     /locus_tag="ACG84X_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFP9126801.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDST"
BASE COUNT        11139 a         8015 c         6936 g        12224 t
ORIGIN      
        1 tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa agcacccgta
       61 gttacgcctg cggtcaggca cagttgcctt atcttagttt gctgaaatcc ttctttttca
      121 aaatggctta gtccactttc tattaacttt tggtgagtta taatataatc tctggtttct
      181 atgggtactt cctcctaata agatgaatta actttattat cttacacagg acttgaagtt
      241 tcaatcgtta acgtttatta ctgaactcat tccttagagc taaactaatg agaaagagca
      301 gaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa atcattcacc
      361 ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta ggataagtcc
      421 tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt cttttactta
      481 aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg aaatcctata
      541 tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc tggactaaca
      601 cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga taattcctga
      661 attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc taccctccaa
      721 attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc gcatagtaac
      781 tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa tagataggaa
      841 tattggtatc ttttgatact gttttcattg gtctatcatc cacactgctt tctacgaata
      901 aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga tctggtgttc
      961 cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac gctttcgaga
     1021 aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga attgaagcaa
     1081 atttagattt agcttctttg tctagagaat ccaatttttc aatatactta tctagatttt
     1141 ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca atatttttag
     1201 cgtaaataat accgttttct aaatttaacc aagcatgagg atcttccttc cctttctcac
     1261 tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag tctttgtttt
     1321 cctctttgtt cgcattttta actaattttg taaaccaagc atttcctcca gtttccaagt
     1381 taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct tcaggcaaag
     1441 gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca attttatctt
     1501 ttgctatatt ttcggtaata tctgctaaaa tcgaattagt aactactact tttaattttt
     1561 cgttcgaagc cactttatct ttgtctttac tatttattga acatgccccg aatataaaaa
     1621 gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc ataacgatct
     1681 ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta caaataagaa
     1741 tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac caataaacaa
     1801 tccaagcaat gatgaacttg ctccgactgt tgcagaaata aatatcatag ttttcaagct
     1861 atttgcatat aaatatgctg tagctgctgg tgtaattaac attgcaacaa ttaatatagt
     1921 tcccacactt tgcatagctg ttactgctac taaagttaat agaaccatca atagataatg
     1981 ataaaaactg acattcatcc ctattgcttt tgccattaat ggatcaaaag aagtgattaa
     2041 taattcttta aaaaatagaa ctactataac caacactaaa accgaaacgc caattgtaat
     2101 ccacttatca atatcttgta cagctaaaat atttccaaat aaaatatgaa ataaatccgt
     2161 tgagctattt gcaactccta taaggataac tcctagtgct aaaaaagaac tgaaagtaat
     2221 accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa taatgataga
     2281 agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa tataagaaat
     2341 tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca ttcctcttaa
     2401 aataataaaa caacctactg ttccagaaac aatccctata actacagatg taattagagc
     2461 attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca tattattccc
     2521 cctctccaat aaatatagta tctccatagg ctttttttaa attttcttca ttaaatacag
     2581 attctacact tccgtgagca attagatttc gattcaaaag aataatatta tcaaaatact
     2641 tctttacctt gcttaaatca tgatgcacaa ttagcactgt ttttccctga tgtttcaatt
     2701 tttttaacgt atccataatt attcgttcac taactaagtc tatccctaca aatggttcat
     2761 ctaaaaatat gaaatccgca ttttgagcaa gacatcttgc taaaagtaca cgttgaaatt
     2821 gtcctccaga taattctcct atttgatgat tagaatattt tcccatatcg accttttcca
     2881 aagcctttga aactctttgc cattctgcat ttttaattct ttgaaaaact ttcattccgg
     2941 catatgttcc catagataca cattctttta cttttattgg aaaagtaaaa tcaatatcag
     3001 ctttttgctc tacatatgca atcttcacca gttttttatt gatatcttca ttattaatgg
     3061 agacctctcc ctgatgaggg ataatattta acattgcttt aagcaatgtg gattttccag
     3121 caccatttgg accaataata cctgttaaag caccttcttg tatttttaaa gaaatctcgt
     3181 tcaatgctaa aaaatcgtta taacaaacat taagcttttt cacttctaac ataactttct
     3241 ccttctaaat gataatgatt atcacgatca tatggtatac aaaaattata ttttagtcaa
     3301 ccctaaattt tatagtttag atttttttct gttgctgaag attagaatga caaaactatt
     3361 tgaaactacg cgtatagtaa gtagctttca aaatatataa aaaaggagcg ttctcaaatg
     3421 agaacatgct cctaaaacta ctttattggc gtatggaaaa attatacttg aagtggatag
     3481 cgggttgaat aagttgataa gcatcaaaac atttataaaa attattcaag actatgtctg
     3541 ttccatatac aaatatgaaa atcagtaaac tccatttaac ttttttcgta gtgtgtcttt
     3601 ttatacatgt ttatcgttat taatagtgaa taggaaaaaa actatttttg atcattgaca
     3661 attaaataca atttttgaat aacgatccct gctattcgag ctagaaactc aagtacgcca
     3721 tgacctgatt agcgacaaat acttagagat ttctttttgt tctgggaaaa caaaatgcca
     3781 tgacaatagc agcaaataat gatacttccg taaggctcgc cgtaaactgg ggagaggtga
     3841 aattcctatg tgcttaccca aagcaattca aaaatttcat aactactatt ttaggagatg
     3901 attttataga atccagagtc tacctgaata aaaaacaaac ctgtgcattt ctaggaatcg
     3961 ataataatac tctagataag tggattcgta tatataattt cccagtaata agagttggtg
     4021 gtgtagttcg ctttgacgta gaagatatta aagactttat gaatacttga aattttcttc
     4081 tcgccgcata tactaaaatt agtgaaatat actgccttac tttttttaag gagtgaggat
     4141 tttgcctaca aagctttcaa atgggaaata taaaactaat ctgagatatc caaaaaggtt
     4201 taaagaaata acaggaattg catcagaaaa gtatcaaaaa acatttccaa ataggcaatt
     4261 ggcgattaaa gccgaaaatg atatgaagaa gaaaatagaa aaagttttga gagaggagaa
     4321 tgcaaactca ttagaattaa aaggaaaaat aacgtttaaa aaattttacg aatctaaatg
     4381 gcttcctaga tatgaattag gtcaaacaat tagatcaaac aggcctccta gtgatataac
     4441 cattagtaat acaaaagata tatttcggtt gcatatttta cctatgtttg gtgaatacgc
     4501 aatgaattat ctaaatatca atactgagat aatatcagat gaattaacca aaaaatcgaa
     4561 agaatatgca aatataaaaa tcataaaagg atatgttcgt tccatgttcg atattgcaga
     4621 aatactaaat tatatcgaat ttaatcgaac tactaaaatt attcaaagta tcactgcacc
     4681 taaaaaaaat gctttagaag aaaaaagaat acaagaaggt aagcaagcac tatcatcaaa
     4741 agaacttact aattggatag aagcagtaaa tgatgatttt aataatcatt tacttacttt
     4801 tcatgattac acacttttta tgattaccct gtatcttggt gatagaaaaa gtgagactta
     4861 cgctttgcaa tggaaatata ttgattttga aaaacaaacg gtccgtctta aacatacttt
     4921 agataaatat caaagaaaaa agtttacaaa aggtcgaaaa gataccgtca ttcaagtacc
     4981 agaagttgta atgacattgc taagtgaatg gaaatcggta caagctgatc aattgttgaa
     5041 attaaaaatt aagcaaacgt tagatcagta tctctttact tatactaaac catctggaga
     5101 agtaaattgt cctgttcatg ccgattacct aaactatcga atcaattcaa ttaaaagaag
     5161 gcatcctgac ttagttcatt tatctccaca caaactccgt catacttatg caactatagc
     5221 tagacaaggt ggagcagata tgaatcaaat ttcaaatgct ttaacacact cagatatttc
     5281 tacaacaaag atatatgtga acacaccaga tatagttgat aaggctgttt ttgaagcttt
     5341 tcagagagga ttgaataagt gtgattgata tgtgttctta aatgtgttct taaaaacaaa
     5401 agaagcactt tccaaataat tgaaaagtgc cagaaacgtt gatatataaa ggatattaac
     5461 gttttgagaa ttgtgaagct ttacgtgctt tcttaagacc tggtttttta cgttcgacca
     5521 tacgtgcgtc acgagtaagt aagccagcac gtttaagagc taaacggaag tcaggatcaa
     5581 cttctagcaa tgcacgagcg ataccatgac ggatagctcc tgattgtcca gcgtatcctc
     5641 cgccgtttac gttaacaaat acgtcatatg cgccttttgt ttcagtaaca gcgaaaggtt
     5701 gattgattac ttcacgcaag tcagcatgtg gaatgtattc ttcaacatct tttttattta
     5761 cagtaatttt gccagttcct ggtactagac gtacgcgagc aactgcgttt ttacgacggc
     5821 ctgtgccgat atattgaact tgtgccaatg aaattccctc ctattagatt aagtttgtga
     5881 tgtctaaaac ttctggttgt tgtgctgcat gtggatgttc tgctccaccg tatacgttca
     5941 attttgtaaa ttgtttgcgg cctaaagtgt ttttaggaag catacctttt acagaagttt
     6001 cgatcaaacg acgagaattt ttagcacgca attcgccagc agtgattgat ttcaatcctc
     6061 ctgggtagtt gctgtgacgg taataaattt tgtcagtcgc ttttttacct gttaatttca
     6121 ctttgtctgc attgatgacg atgacgaaat cgccagtatc caaatgaggt gtgaaagttg
     6181 gtttattttt accacgtagt acagatgcaa caactgttga aagacgtccc aatggaacat
     6241 cagttgcgtc tactacatac catttacgtt ctacttcgcc tggtttggcc atatatgttg
     6301 tacgcacgtt attttcctcc aatttaagtt ctgatgtttg acatacactt cgagtttccg
     6361 gggctctttg tggggcaaac aataccattt aacatattac ccgctaatct agtcaatgtc
     6421 aacgtttttc tgcttgattg aaaaatttat atgaaacttt acttcttttc tttcttttat
     6481 ataaaagggt cgtttcctgt caaaatgaaa aacaaaaaga ggctgtgaca aaagtcttgt
     6541 cacaacccct tattttgaat aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca
     6601 atatccataa aacataagaa gctgtttttt aaaattgttt cttgtgactc ggagctgaac
     6661 ggcaggctta caacctcttg gtaaacggtg ttcaatcagc tgaccctcgg tattagctca
     6721 aaaaacggca aaatatgagg aactattttg acgtttgttt ctctaatact caggtcaaaa
     6781 cgctgatttc acaacctctt tttcggtcaa gttcaacaac agtttttacg cgtcgatctc
     6841 tggcgctttg cccaaatgag cttggatcat ccagatacgt ttttctgtgg ctgttttgaa
     6901 ttcgataaag atatcttgtg ttggatcgtc gccttcttct ccagaaactt cgattccttt
     6961 ttggtaaaga tctgctagat aacgatagcc tgcaacaagt gtttccaaac gttctggaat
     7021 agtacgatcc cagcggccaa tttcatcagg gatttttgtg ttatctgcaa attcacgcaa
     7081 tgtagaataa ggtgaaccgt ctaatgtgat caagcgttcg gatacttcat ctaactgagc
     7141 gttcaaatca tccatgaact catccatcat tgggtgcaat gtaaggaaac ctggtcctct
     7201 catgtaccaa tgtgtttggt gaacaacaac agacatttgg cttagatctg caactaattg
     7261 atttaatact tctttggttt gttggaattt catctttctt gcctcctaac attttcttac
     7321 acttaaaata atagtagact ttcaatgaaa agtacaacaa aatcatttac ctgagaacga
     7381 ttttcagttc gcttttttat ccgtaaagcc aatcattttt cagaatcagc taattcttct
     7441 cgcagttgag caaattgctg ataagtctgt gctaaatgct tttgtgtcga aacaaataat
     7501 ggatagattt tctgatattt tttatgatca gtttcttgta ctccaacttg ctctttcaat
     7561 tctatcaatt cctgtgcttc actgatactt tggatctttc cgatgcttct ccagcctaaa
     7621 atcacagctc ctaatgcgga tgcttctgtg acagtaggga aaacaagcgg gtaacccagt
     7681 acatcagcca tcatctgacg aaaaatcgga gattgagcaa acccgcctgt agcacggatc
     7741 tctgtgagct gattttcctg gcaaactcct tttaaaatcc gataaaggtt gagacagatc
     7801 ccttctagaa tcgccttcat catttctttt tctgtatgtt gccgctgtaa accgataaaa
     7861 ctgccaaacg catctgcgtc ccaaagcggt gctcgctcac caagtaaata gggatgaaaa
     7921 atcagaccat tggcacccgc tggcacaaaa gcgatagccg aaagcagtgc atcatatgga
     7981 ttttctcctt tttctttagc agattgaacg acttcctgta aaaatgtatg ccctgcccaa
     8041 tcaaagatgc cagcaccatt gctagtcgct cctcccacta cccaatgttt ctgatccaga
     8101 acataacaaa acgtctccat ttctggatgg aactgaggct gagtagtaat aaaacgaagt
     8161 gctccgctcg ttcctacggt caaagcggcg atcgtatcac caaaagcacc taaccctaga
     8221 ttagaaagcg gcccgtctgc ccctcccaaa acaaatgata tatcatttgg caaacctagt
     8281 tctgctgctg tttttgatgg tagacctgtt acttgatagg tggaaggaaa gacttgcggc
     8341 aattgctcta ttcgaatgtt caagtagtca agcacttctt ctgcccattg gaattcatgg
     8401 atatcaaaat atccagttcc tgaagctgtt ccgtagtcgc tgatcagttc gccaaacaat
     8461 ctataaaaga tatagtcttt gataccgaca aaataagcag tttttttgaa taattcaggt
     8521 tggctgtttt gcagccactt gattttgttc aatggtgtca ttggatgaat cggcgtccca
     8581 gtctgccgat aaaattcttt gccaagcacg gtatatttca gtttttctgc ttcgtccgct
     8641 gctcggttat ctgcccaagt gatcattcga gataacggtg ttttctcttc atccaacaat
     8701 atcaggccat gcatcgcaga ggagaaggag acaaattgaa tgattgtgtc tgaaggcaac
     8761 tgtttaatta cttcttttat aacggtgcag acaccttgaa agatcaattc ctgatcttgt
     8821 tctgccatcc cttgtgtttc ttggatcaaa gggtagcgaa aataagcgga tgctgcttct
     8881 tgggcttcat ctgtgaaagc aactgctttg gtttgtgtgg ttccgatatc taatccgatt
     8941 gaaacgttca ttttttcacc tcaaatttta tgtatgtaca aaaatttagt ttaagcttgc
     9001 gtatcttggt tttgaaaagg gggagatggc gtgttacttt attttatcat tggttgctgt
     9061 atcggatcat ttttatgttt aaccgcccag cggattccgt taggtcactc tattatttat
     9121 cctagatctc attgtgtcaa atgctgtcgt tcgctttctt ggtatgaatt gattccgatt
     9181 ctctcgatca tcgtccaacg atttcgctgc cgctattgca ggtgtcggtt gcccttctac
     9241 tatttgttgg cagaagcctt atgtggtggt ctttttgcct ggttctttac tttttcttcc
     9301 gcaagaaatt tttcgacgtt catatggatg ctttcggctt tgctattttc gttgatggat
     9361 ttattttact tcatggtcca ttctcacacg ctattctgtt cttgggcaat tttatggatt
     9421 ttttggttgc aggccggcgt cttccaatgg caaagtgtgc tgttaacgtt tatcgtaggc
     9481 ggtgtgtgcc ttcgctatgg tcaatcctat ctcggagctg gcgatactct gttgatgctt
     9541 tcttggagtg gtggcttgtc tctagaagag ttgcttcaga tcttgtttct tgctagtctg
     9601 tttggaatat ccgttttttc tgtttacttt atctgtcata aaaaaaagtt ggaaaagctg
     9661 cctttcattc cttttttgag cagtgcgttg ctgattgtcc ttcatcttag gtattgaaaa
     9721 aaggttgtga caaacgactt gtcacaacct ctgatatata gtgttctctt accaaatcct
     9781 tgtgacttgg agctaggcga caggttcaca acctctccac taaatggtgt tcaatcagct
     9841 gaccctcagt attagctcaa aatgctggtt ttacaacctc tgatatacgg tgttccataa
     9901 gtagcttttt cggcttctta tttcttgacg ccccaatgtc gacgaaggaa acctgcacgt
     9961 ccagaacctt ctcgataaag attgtaatgg agcttgtttt tcttgtaata atcctgatgg
    10021 taatcttctg caggataaaa ttcgcttctt ggttcgattt ttgtcacgat tggcttatcg
    10081 aatcgcccgc tgtcttgcaa tgcttgtttt gaacgctctg caatatttcg ttcttcttca
    10141 tcattatagt agatcactgg acgataagaa tcaccgcgat cagcgaactg tcctaatgcg
    10201 tcagtcggat cggtttgctg ccaatagatt tccaccaact gatcataaga aataacttct
    10261 ggatcatatt cgatctctac tgcttctgta tgccctgttg tgcctgttgt tacttgttca
    10321 taagttggat ttggtacatg cccgccagta taaccggatg tcacagaaat gatccctggc
    10381 tgctcttcaa atggtttgac catacaccaa aagcatccgc ctgcgaaaac tgcttttttt
    10441 gtcatataaa atcccccttt tttctcatca taccttgatt tccaaaagga ggataacgtt
    10501 ttgcttgtga cagaaaaaac ggaaactatt atatacgtga tacggcttct gataaatgcc
    10561 aaaacgaacg tacttgatca aaaacggtta aatcaggaat cacatattca gcagaaggaa
    10621 gatttatgtt ttcacctatt cccaatacat gcatgttacc agccaaagct gcttgacaac
    10681 cagcttctga atcttcaatg accaagcatg catttggcgg tacattcaat tgctgtgctc
    10741 ctttgagaaa aacttctgga tcaggttttg cttttgatac ttgcgtgccg tcaataagga
    10801 catcaaaata acttgtcaaa ttcgtttttt ctaaaatgag gcgtgcattt ttgcttgctg
    10861 atcccaatcc gatcttgatg tttgtttttt tcaagtactc aagaacagct attgcaccag
    10921 gcaaaacgga tgtttcatcc attttttgaa tcgcttgaag atatagattg tttttttgct
    10981 cagcaaaggc tgatttctct ttttctgaga atttctgttc catttttcca aatgacagca
    11041 atcgctctag tgactcggtt ctggatattc ctttcagttg ctcgttttct ttctcagtga
    11101 atggaatgga cagctggtta gctaaaacca gccacgcttc gtaatgataa cgagctgtgt
    11161 ctacaagaac gccatctaaa tcgaatagtg ctgctttgat tttcatcgat tacctccttg
    11221 aaaatgaacg acttgaagta aagatgcgat gtttttagct gtgcgatgaa gattatcagt
    11281 ggcttgctgt aaagcttctt gtaaaggcac agctgcagga aggatcggaa aaacggccga
    11341 aatgccaaca tctgctgctt tttcgcttcc tttaccaaca cttccgcaaa tagctatcac
    11401 aggaacgccc tctggtactc ttctagcaat cccaactggc gcttttcctt ttagactttg
    11461 tccatctaga cgtccttcgc ctacgattac gaggtctgct tgctgtaccc gtttatcgaa
    11521 ctccagtaaa tccaatacgt agtcgatgcc agagactatt ttccctgaag caaatgctaa
    11581 cagtcctgca cccattccac caccagcact actgcccgat gcctcgatta cttgaggggc
    11641 aaatctcata taaaaatcat gcatggcttg gtcagccact gctaattcat tttctttcaa
    11701 gcctttttgt ggtccgaaaa caaaagaagc gccttctttt ccgcataaaa gattagtaac
    11761 atcagtaatg acagtgattt tggctttaat cagctcaata ggcacgttcg ttttatcaac
    11821 tgtagcaatt ttacctagat tttctcccag tgcttctact ttttgattat cttgatcgta
    11881 aaaagcataa cctagacctt ctgccatgcc gatgccgcca tcgttggtac tacttccgcc
    11941 aacgccgatg atgatgtgtc gaacaccttg ttgcaacaat tgtcgtatca gttctcctac
    12001 tcctcgcgtg gataacctaa gtggctgttg ttggtttagt gggacatctt tcaatccgac
    12061 gatttctgcc atttcaaaaa tcgcagtttg accgtctgaa gcgtactgga tttctttgtt
    12121 tttgccaaat gcattagtaa cgactgctgt ttgccgcttc aaccttaaac tgtctgctaa
    12181 tgatgaaacc gttccttctc ctccatcgcc tataggtagc agatcatatt cagcctgaac
    12241 aaaaacttct tgaaaacctg attgaatggc ttgtgctgcc tctaaggctg tcagactttc
    12301 tttgaaagaa tctggcgcaa tcagaatacg cattattttc ccctccgttc caagatcagt
    12361 tctttttcca gctggtattg gtctccattg acaaaaatag gtaatgtttc tttcgtctct
    12421 ttttttatta ctatttgttt ttttgtcaaa acaaatagca acctgtgatt tttccaaata
    12481 aaaggaaaag aaattttttc ccatgctgaa ggaagtcttg gagaaataga aagagttcca
    12541 ttcgttactg taatacctga aaaaccaaat ataactgcta gccatagtgc tcctaatgaa
    12601 gcagcatgaa ttccgtcatc tgatgaatgc ggatctggtc ctaaatcaat caggcacgct
    12661 tcttggaata aatgatacgc ccattccatt tcttggatac ggcaagcctc tatggcgtga
    12721 atcgctttac tcaacgatga gtcgtggatt gttttgtttt catagtaatg caaattctta
    12781 gaaacgattg gttgagaaaa atactcaggt aataagtata acagcatgac aagatctgct
    12841 tgcttgctga cttggagttc atttacttcg ctacgggcat aatcaagtaa aatagactgg
    12901 ctgccaggac gttctttgta agtggtcaaa tcaataactg gcttactgag atacgtgtca
    12961 tcttgcggaa tcagctgttc tttgttaggc actggcaaat ataacttatc taaaaaattt
    13021 tgacattctt tcaaaaaaag cggatcgcca gcttgatatt taacagctaa ggccacatta
    13081 taatgcgcca gatagttcgt atatgcatta ttgtcgatat attctgtgta ttcatctgga
    13141 ccaatgactc tgtgtatctc taaatgatca tcgactttta cagctctgct cagccaaaaa
    13201 gctgctgttt catgaatgag cgtttttccc tttgtttcta aaaacgattg atcctctgtt
    13261 gcttggacat actcttgaac ggcataagca aggtctgcac tgatatgatg ttctgcggca
    13321 gctgaagcaa cttcttgtct tgttccggtt ttgatattca atgcagcaaa tttgggtgtc
    13381 tcttcctgac cagtgtgtgc gctttcccat gggaaaagtg caccttgata gtgataatct
    13441 cttgcttttt gccgtgcgcc ttctaatcga tcataacggt acagcagcaa attctttgct
    13501 acttcaggaa actgatataa aaagaaaggc aggataaaaa tttccgtatc ccagaaaaca
    13561 tgccctttat aaccttcgcc agttagtccc ttcgccccta cactaacact tggatcattg
    13621 cggggagtca taatctgtaa atggtaagca gcgaagtcca tcgctaactg atcgaaagaa
    13681 gaatcgcctt ggatcgttat ccgatgctga tgccaaaaat ctgtccaata agacatcgac
    13741 tgctctaaaa tttctgtata actaacgctt ttctgggctt gggcaatact tttcttaaac
    13801 gggtctgttt gctgaagaga ggtagagagc acgatgatct tctccagcgt aaaggacgta
    13861 ttttttctga tcttttctga aaaggaagcg gtgatccggc gattttttgc ttggaataca
    13921 cctgctttat tgaatttagc tgcaatccca atatcaattt tactttctgt tgtctggtag
    13981 gatgcactga tcaaatcgtc accaaatact cgcagttctt tttcaaccaa ctgctgtgta
    14041 ccaaaattgg tttgctgtcc atcgataccc gttttcacat ctacttggca gtcttcggtc
    14101 aacggcttga tgaccacttt cagggctgcc tgatggagat tattttgatc agcaacacga
    14161 caagtaatga cttccacttt ttttccttga gcagtttcaa tgagcgcata gcgtttaagc
    14221 tctcccattt ctaaatctag tgcccgctcg tatgcaagaa ctttcatcgt ctcaagagaa
    14281 aaatgttcac cgtcgatttt tatttcccat ctgatgacat ctgggagatt cactaactcg
    14341 gctgattctg ctcctaaagg tcggttatat acaccagctg caaacattcc ccttacttga
    14401 ttccgatagt cttcctcctg gcttcctctg ataccaaaaa atccatttcc aatggtcatc
    14461 tgactcgcat acttattgat atactctaaa tcaaactgtt tttcttctac tttcataagg
    14521 taataacttc tcctgtttct gccgaacgat ataaattttc caccagattc tggatgacat
    14581 atccttgcca gccatctgca atcatctgag tctggtcacc gagcgcccga ttcacaaaat
    14641 gagccatact tagttcatgt gggtcattaa ctggcgtggt cttttgtaag gaaaccagct
    14701 ttccatctac atcttcgaat agttcgcctg gatacagatt agcacctgcc tgatcgccac
    14761 aaaaagccac attcagtttg tcttctctga tattcaaagc aaacgaagta ttcagttgga
    14821 tgatcttgcc gttttctaat tccagtgtgc caaaaattgc atcttctact gtgaatttgc
    14881 ttggatccca tttcccgaat ttccctgaat tttttttcgt accaattttt tggaagctgt
    14941 acgcccgaac gctttttact ttaggaaatc cagtaatata catcgctgta tcaagcatgt
    15001 gaatgccata atcgatcaaa ggcccgcctc cttgaagttc tttgtcgata aacgttcccc
    15061 agcctggaac accagaccga cgaagcgcat tcgcttctac gtaataaata tccccgagaa
    15121 catcaagatg attcttgatc attgttgctt cgtcagaaaa acgatgctgg aatccataag
    15181 ccaaaatctg cccgttttta tcggctgtct ctgccatctt tcttgcttga tcagctgtca
    15241 tagctggtgg tttctcgcac atcactgaag cattagcttc gagggcagcc aatacatgtt
    15301 cgaagtgaaa gcgattgggt gtacagacac tcacgatatc gggagaaatc tcattcagca
    15361 tttgtgtaac tgatgtatac gcatgagaaa atcctgtacg tcggcaaaag tcttctgctc
    15421 gctggctgac tggatcaacc acagcggcca attctaagac atctgatctt ttttgataat
    15481 aagcagcatg tactttttct gctacttgtc cagcgcctat gattgctact ttcttcattt
    15541 atttctccct cctttgctta tttacttatt gttattcttt ctctattctt tctctaaatc
    15601 atttaaatga cgcgctgttt ccagacagtt tttcaagtat tgcaatgatt cctgataaat
    15661 tttcacttca ttttctcctc gcaaacgaca ttcatatacc atataacctt catactcatt
    15721 ttgaagtagc gtttgaaaat ggcgagtaaa atcaattgcg ccagatcctg gttggtagcg
    15781 atgattatct gctaaatgga tatgacccac atactctttt tgcgtagtca atgcttttga
    15841 aatatcatct tcttcaatat tcatatgata aaaatcagcg atgatctgca catgtttcaa
    15901 ttgattagag tcaatgtaat gacgcgcatc cgctaacaaa ttgatcatat ggtcttggta
    15961 tcggttcaaa ggctccaaat aaataaccgt acctgtttct tcggctactt tatctaaata
    16021 acgaagtgat tcgctgactg ctttatagtc tccttctttg cttcggggtg aaaccatcgg
    16081 cggtaatcga taagtgaaca ttccccaagc tgctgggata acgattcctt tgcctccaac
    16141 ctcgcttagt gcacgcaaaa tctcagcaat ttgacgtaca ccattaagac gccgttcttc
    16201 gataaagtca ccgatccacc catcgtagcc gttacaagct gtcactactg ggatccctgt
    16261 ttctttgatt gcctgtttga ctgtgtcgat attttctatt aacaacttac cgtcgatttc
    16321 gtattcttca aatccacagt ctttgataaa tctaaatttt tctaaaatgt ctcttgggaa
    16381 aaatgcttga tcttgcgtac cgaatttcat tgttctcctc ctcggacttg aacgcccatt
    16441 ttgatacttt cttctgggtg ctggtctaca taacgcatgt aagcttctgc gctttctgca
    16501 aatggcacaa ctggatcaat gatttcttca caatccaagt aaccgttcat caataattcc
    16561 caacatgtgt cctcgattcg tttacggttc catcttgggt aatctgggtt tggttcacta
    16621 gatgctcgag caaagacgat ttttgcatta ttgaaatgtg cttcgcgacc aagattaaac
    16681 ccagctggaa aaggtttagc aaaggcaaca taagaaatga tcccgccata gccgatccct
    16741 cttaaagaag cttgtaatgc ggcagcactg ccactcgttt caataactga atctactcca
    16801 cgtttatctg tcaattcctt tagacgaaaa ccgacatctg ctttcatagg atctagcgtg
    16861 taatcggcac cgtatttttc tgctaattct ctacgctgcg ctatgggatc gatcccaacg
    16921 atggtagtag cacctgcttt tttagctaat tgaatcgcaa tttgcccgat agcgcctaaa
    16981 ccgaagattg ctacagcatc acctgctcga acatgtgctt cccggatacc acctaaagcg
    17041 aattgagcag gatcgtaaca tactgcattt ttccattgat ccaaccgatc aagtttacgt
    17101 agtttataat tatcaacacc gtttgtaatc agcgtttcac gaatgggtcc ataagtgcag
    17161 actaactctc ctttttgata ctctgtcacc aaactgcccg tttcttcgat cgtaccgaca
    17221 atcatatttc ctaattgaaa ttcgccaaat accacaccgc gttggcttcc ttcttctctt
    17281 ggcaagaata ggcgccattc ttctgaaaat tcttcatcga taaatggact taatcctcta
    17341 aagtcgacaa tttctgttcc tggttttgga gtagcgaaaa ttactcggat acgtacttcg
    17401 ttcttttcga tctcacggtc ttcgtaatct ttgaatccgg ctattcttgg ttctaatgca
    17461 actaattttt tcatcttttc tttcctcttt cttttctttt tatcctttta cgccgccttc
    17521 gactaaatca cctttaataa atcgttcaga taacgcatac ataatgatga ctggtaaagc
    17581 ggtcaccaat gaagcggcca tcattcgtcc ccaaatgtag tctggtgtac tgaataatgt
    17641 gttcaaaccg attggtaaag taaatttttc ggaggtcgac aggaaaatcg aagcaaataa
    17701 ataatcattc cacgaaacca taaagcaata aacgaagaca gaaatgattc cagaaatagc
    17761 caatggtata atgatccgaa taatgatctg gatccggcta agaccatcga tcattgctgc
    17821 ttcttcaata tcagtcggaa tcgtgtcaaa ataacttttt agcatgaata tcgcagtagg
    17881 aagtgtttga acgaccatcg tgataatcag tgctgtattg gtatcataca aacctagacc
    17941 ggaaatgatt ttaaataatg gaacaacgat caaaataccg gaaaacatat aaacggtgta
    18001 aaagctagca ttgattttcg agcgagcttt gaagcgtagt tttgacaaag cgtatgcccc
    18061 gctgatccca atcactactg cagttacgga ggctatcaag gagatcacta aactattttt
    18121 gaaatacatg atgaatggaa aaatctcagc attgaaaata tcctgataat gttcaaaagt
    18181 ccattctttc ggaaaaatag tttgtgtcgt tgcaattgct tcttgtgaat ccttgaatga
    18241 tgtcatcagc atgatcaaaa atggaaacaa attgacagct aatagcaaca aaatcgtcgc
    18301 gtaaaataag attttcctgc tctttttatt tttcatttca agtccacctt ctttcgtgag
    18361 agcaagacga ccgctgcaat aatgatgaac aatagaatcg atatagctgc tgcttttcca
    18421 agatcattga acgcaaaggc tgtctgatac aaataaacgc ctaagatatt gactttattc
    18481 gtcagtagat agacatctgt aaacatatag aacatccaga tagatcgtaa aacaatcaca
    18541 gttgctagta ctggtttgat tgccggcagt gtcacgatct tgaacttctg ccaagcattt
    18601 gcaccgtcca tttcagctgc ttcataaagc gttttgtcga ctgtttgcaa aatagccaaa
    18661 aatgaaataa acgcatacgg atagtatctc cagatagcaa acaaaacgac cataaagaag
    18721 ctagcaactg gctggtcgaa ccacagcggt gcttcgttga aaagctgcaa cctatctact
    18781 aacagatcat tgacgattcc ataactatta ttgaacatat atttccaagc aaaaatcaaa
    18841 gaaatagatg gcgtaacata acttaataaa atcagtgaac gcaccgtttt cctaaatctg
    18901 aacttgcggt taagcaaaat agctacggct aatcctaaag ctgtactgcc tgctacaact
    18961 aagaatgtgt aagcaactgt taaacctaaa gaacgataaa attcactatc acttaaaatt
    19021 tcaagataat tgcttaatcc gataaaaacg gcgtctgagt taggattcag cggcatatcg
    19081 aaaaaactga tctgaatatt ggaaagcatt ggaatcagca ctaaaacagc taataaaagc
    19141 atgcttggtg ctaaaagtcc catggctaat tttaagtcag aatgtttcct tggacgattc
    19201 attgaaacct ccccctgata atctgccaat agctatctac ttttttcgaa caccattggc
    19261 agaacttctt gttatttcgt atttttttgt gcgtcagcta aagcttgatc gacatcttcg
    19321 tttccgacag ttacttggtt cactgctttt ccgatcacac ctgagcttgt gatatctccc
    19381 attttcgtga aattcttttc cccgactagt ccaaagactt gtacttcatc aaaagcacta
    19441 gcaatctcag atggcagctc gccaaaagac ttgatgactt cattttcttt gtaaccatcc
    19501 agttcgacta cttgtttatt cactggttga gcaccaccag gagacatcaa gacccacttt
    19561 tccatgtttt tcggttgaga taagaaagct gtgaatgctt cagcagcctc tttttgtttc
    19621 tcgtctagac cagaagaaat cgtcaatcca gatactgtgc catagacagc ttgatctttt
    19681 tgtgttggga tagcaaaacc gatattttct gagttccccg cttcataaac agaaggcaaa
    19741 atgtaagttg aatagattgc cattggtgct gttccattca tgaaagcatc tttgatttct
    19801 gtcacatcat tagagcctgg catcgtgtat tgggataagt tttgataaaa cgacaatgct
    19861 tctctcatct tttccgtatc gatcgttacc tcgccttcat catccaaaac atttgctcca
    19921 tttgacaaag caaattgaga gaacgcttgc tcactcattg ttccttcagc agtaggcata
    19981 gcaattccat attgtttatt ctctttatct gtgaaatgtt gagcaatttt taaaatatca
    20041 tcccaatttt ctggttctga aaaaccagct tctgataatt tttctttgtc ataccaaata
    20101 ccttgaaccc agccgctaat tggtgcagca atatagcttt ttccatcttc tgaacgaaca
    20161 aggtttttgg ctccgtcata ataattatct tctccagctt cctcgataac gttttggact
    20221 gccgtctgat caatcagttc atctttatcc atcactttag caaaatcctg actgacttcc
    20281 attacttctg gtaatttacc ggaacgagct aacgtaacga tttttgtatt gaacgctgat
    20341 tcttctaccg gcacttgctt gattttgatg tctggatttt ctttttcaaa atcagcaacc
    20401 agttcattga tcacacttaa tcgttcctgt tcgacagaag agtgcatgaa ttgaatcgtt
    20461 gtctgttgtg attcgttaga gctttgactt tcaccacaag cagtaagaag aaatccagta
    20521 gctagcagac aggtagtaac aataattttt ttcatttttt tccacctctt attttattat
    20581 tttcagccac atatattcat acggctggaa tatcaacttt cgttcttgac tgcaatggat
    20641 aatttgtcca gaaaacaggt ctaggtaatc tccttttggt aaaagataac ctgctgattg
    20701 attggaaaaa ttatggataa ctaagacttt ctcttccttc gcttcgcgaa taaaactgat
    20761 aaaagaatct gctgagtcca gtaagtaaat caaactattc ggatggaagg ctttttcttt
    20821 ttttcgaata gatagcatct gggtcaattc accatatact gctgttctta atggatctgt
    20881 ctgcaactct ttctcaatat ctgctaacaa aaatttttgc cgattgattt ttcgattctc
    20941 tcctgttttt tctacgcctt tgtaatcatt tcgacttccc agcacacttt gaatataaat
    21001 tgccggcacg cctggtaacg ttaccaaaaa tgaatgagca gctaaaaagc gtttgcttct
    21061 ccattccgtc gtatctgttg gagaacttaa cgcatctaga tacgtagcgt ttatctcata
    21121 tggactggtc gttccatctg ggtttttctt gtagtttact cgggtaccct ctttcttcag
    21181 ctgttccact aattcaagga tcgttttttc cggcagaata cctcgtaccg gattcaatcc
    21241 gataccgtca tgggaggcta aaaaattaaa aaaagttgtt tttttcgatg cgaaatcgat
    21301 ggtttttaac cattctttca acttacttgt attacccgaa cgaatcgctt gaagggtcaa
    21361 aggtggtagc gaaaactgat agaccatctg tgcttcattc tcgccattcc caaaataact
    21421 gatattatct ttgtgtggca catttgtctc agtgatcaat accgttcctg gagctgcttc
    21481 atcagcgatt gcacggaata attggatgat tttatgcgtt tctggcaggt gtatacaaga
    21541 agttcctagt tctttccata aaaatcccac agcgtccaag cgaataaatg aagcgccttt
    21601 ttctaagtaa aacaaaagaa tatcgatcat tttcaataaa acttctggat ttttaaaatt
    21661 caagtctact tgatcttcgc taaaagtcgt ccatacgtgt ttttctttcc cgtttttgtc
    21721 aatgaacgtt gtaagtaacg ggctggtcct tggtctagtc acgctgcttg tatctgtatc
    21781 cagtggcaaa tcaataaaaa aatctttgta cgtatcattc aagtttaaat attcctgaaa
    21841 ccaagtactt tcggcagaca tatgattgca gacaaagtcg aacattaacc gtgtttcgct
    21901 tctcatttct tctatatctt cccatgtgcc caaacggtcg ttgattgcct gataatttac
    21961 aacggagaaa ccatcatcag atgtatatgg gaaaaatggc aagaaatgta caactctaaa
    22021 tgtatctgcc aaatactttt gataaaattt cttaaatgta cgcaaagttg gttgctgctc
    22081 ttcaaaaaat tgatccccat aagtaatcaa gaaaatatct tcttcgtccc aatgcagttt
    22141 gcctgcctgg cctttcttct gctgataaac actgactttt tgttcaatca tagaggcggt
    22201 tttctcagac aaatctgagt cgcgataaat cgcttgtaaa agttttgtat acatcggatt
    22261 cccctttctt ttttgggagc gttcccaacg atttgatcat attatggaaa acgcttactg
    22321 tcaatagcat ttttttaaat aattttgata tacacaaaaa tacaaataag aaagcttatg
    22381 tatcaataat taatagcttc ttaaaaaaat atggtctctc atgatcatgc aagctattcc
    22441 taaattttca aaatcataga caaaaaagaa tgtctattgt actatggaat tattctaaaa
    22501 cgctcccaaa aaggaggtgc atataaaatt gaaacctact atttatgaca ttgcgaaaaa
    22561 agctaatgtc tcaaaatcaa ctgtctccag agtattaaat aaccagccaa atatctctga
    22621 taaagcaaaa gcaagtgtac ttcaagcaat caaagaattg aattatgaac cgagcaaaat
    22681 tgcaagagga ctgtcaggaa atggttttga cgcgattcta gcattatctc atcgtacttc
    22741 tcatacgacc tatggcaatc cttttttttc agatgttatt caatccattt ctgccgtttc
    22801 tgaacaaaat aacttcgact tgattctaca aacggcaaaa acaccagaag aagagctaga
    22861 aaaatgcgcg aaaaagatcc aagaaaaaat gatccgagga attattattt taagctctac
    22921 gatggatgaa acacttcttt ttgaattgga tcaatacaat attcctattg tggtaatcgg
    22981 aaaagtcgga aacgactaca cgaacatcta ctcagtggac acggataatt tccaggatag
    23041 ttacgatttg gtggaaacac tgatcaagaa tggacaccgt catatcggct gtctccatgc
    23101 tccgacagaa gtttatgtat ccaatgatcg tctcaatggt taccgtcaat gcttatttga
    23161 tcaccaccta gatatccgta atgaatggat tatagacggc ggctttcgct tagaagatag
    23221 catggcagca atgaatgatt taatgaagct acgagaaaga ccaactgcga ttttttctac
    23281 cgatgcatta aaatcattga gtatttacaa agtggcagaa caatctggaa agcagatacc
    23341 tgatgatctt tcgatcgcag gattcagtga tcccttattg tcctccctat tttcgccaca
    23401 gttgactcgg atagacattc cgacaaatca gttaggaatc aaagccacag aacttttatt
    23461 ccaactaatc caccaccaat accctgaaga aaaaagaatc attctttcaa ccgagattac
    23521 tctcacagat tcgatccaac aacaagaaat gtagaacaga attataaaag aacagaaaca
    23581 ctgaggataa gtcagttact ctgttctttt ttcaatcact catccctcgt taccccctcc
    23641 cggtatttta gcgaattttt cttattttcc atctgtttta gatagctgtg gataactata
    23701 atgtttgtgt taaactattt tttccacagg gaagaaaaaa ctatttttaa ccacgttgtg
    23761 tataagtttt tatagttcgt ttttttaaac acatttaccc ttatttcaat ccatgttatt
    23821 tggggatact tatctctaaa acataaatag aataacagac atgtctactg gttttgtttt
    23881 attcgaggaa ttattcaata atagctagca aaatattaaa aataaccgct ctatcttccc
    23941 atcaatttat tttgcattca aaaaatgatc tatctttact tttgttgatt gacttctctt
    24001 ggaagatgat cgttccgata ccttaattgg atacgaaccg atgttgttaa gatcctttcc
    24061 cacttttctt ctagttagac aaattatttt agacaaacca aaaaagaggt tgtgacaata
    24121 atttgtcaca acctcttttt taaaatatct attttgtttg attgttcatt gcgtcttctg
    24181 cagccatttg cgcttcaata tctgaaatac tgtagacatt ttcgcttgct acaccgactt
    24241 cttttggttc catgtcacga taacgttgca taccagtacc agctgggatg atcttaccta
    24301 taataacatt ttctttcaaa ccaagaagag gatctttctt accgcggatc gcagcatccg
    24361 tcaagacacg agttgtttct tggaatgatg cagcagataa gaaactattt gtttctaatg
    24421 atgcttttgt gatacctagt aagacaggtc gagaagttgc aggaacgcct cctgagacta
    24481 gcgtattgta gttttgatct ttaaagtctg cgatgtctaa taatgtacct ggtaagatat
    24541 ctgtatcacc tggatccatt acacgaactt tacgcagcat ttgacgaacc attacttcga
    24601 tatgcttgtc gccgatttct accccttgca tacggtaaac acgttgtact tcacgaagca
    24661 agtagttttc aacagataat acatcgcgaa cttgcaacaa ttgttttgga tcgattgatc
    24721 cttctgtcaa tggtgcacca cggtggatca tatcgccttc tgctactttc atacgtgctg
    24781 tataaggaac agtatacgta cgtgtatctg tttttccttt gattgttact tctttggtac
    24841 gtgttgcagg atcttctgag atatcgatga catcccctgt tacttctgtg atcactgctt
    24901 gccctttcgg attacgtgct tcaaagattt cttggacacg aggaagacct tgagtgatat
    24961 cgtctccggc aaccccacct gtatggaatg tacgcatcgt caactgagta ccaggttcac
    25021 cgattgattg agcggcgatc gtaccaactg cttctccgac ttcaacgtca gagccagttg
    25081 caaggttgcg tccgtaacaa tgtttgcaga caccatgttt tgtattacat gtgaagacag
    25141 aacggattgt cactgtttcg acacctgcat caacgatttg ttttgcgatg tcttcggaaa
    25201 tcaattggtt tcctgcaatg atcaattcat ttgtttcagg atgacgtact tctttacggg
    25261 tgtaacgtcc cactaaacga tcttctaatg attcgatgat ttcatttccc tcgcggatgg
    25321 cttggatttc aagacctcgg tcagtaccgc aatcttcttc acggatgatt acatcttggg
    25381 ccacgtcaac cagacgacga gtcaagtaac ctgaatcggc agtcttcaag gctgtatcgg
    25441 tcatcccttt acgagccccg tgagttgaga taaacatttc caagacggat agtccttcac
    25501 ggaagttcga aatgattggc aattccatga ttcgaccatt aggagcggcc atcaaaccac
    25561 gcattccggc aagctgtgta aagttggaaa tgttaccacg agctccagaa tcagacatca
    25621 tgaagattgg atttttcgct tccaaacctt ccatcagttt ttgttggatg ctgtcttttg
    25681 cagcattcca aacagcaatg acacgttcat aacgttcgtc atctgtgatc agaccacgac
    25741 ggaattgttt tgtaatagtt tcaacttgtt tatgggcatt ttcaatgatt tcttgttttt
    25801 cattcagtac actgatgtca gcgatcccta ctgtgatacc ggcatgtgtc gaatgtttgt
    25861 accctaagtc tttcatacgg tcaagcatct tagaagtttc tgttactttg aatcgtttga
    25921 agacttctgc gatgatgttt cctaagtttt tcttcttgaa cggtaatact aattcttgct
    25981 ctttgatatg tgcaggaata tcagtaccag cttcaacaaa gtatttgtcc ggtgtttgga
    26041 cggtcaagtt gaagtctgtt ggttcattca gataagggaa ttcaggaggc atgatctcgt
    26101 tgaagatgat cttaccaact gttgtgatca tcgtacgttc tttttgccat tcagtaaatg
    26161 gtttttcacc taatgagtta gggttcacac cgatacgtga atgtaaatga acatatccgt
    26221 tgcgccatgc gataacggct tcgttttgat ctctgaagac cattccttcg ccttcgcgtc
    26281 cttcttcttc cattgtcaag tagtagttac ctagaaccat atcttgggaa ggagtaacaa
    26341 ctggtttacc atctttaggg ttcaagatgt tttgagcagc taacatcaac atacgtgctt
    26401 ctgcttgtgc ttcttcattc aatggaacgt ggacagccat ttggtctcca tcgaaatcgg
    26461 cattataagc ttcacataca agtggatgca aacggattgc gcgtccttgt actaaaactg
    26521 gttcgaatgc ttggatacca agtcggtgaa gcgtaggtgc ccggttcagc aatactgggt
    26581 gttccttgat tacgtcttct aaaacatccc atacttcgtc ttcttgacgt tcgattttac
    26641 gtttcgcatt tttgatgttt gaagctagtt cgcgttgaac aagctcacgc atcacgaatg
    26701 gtttgaataa ttcaatggcc atttcttttg gaagtccaca ttggtacatc ttcaagaaag
    26761 gtccaacaac gataacggaa cgacctgagt agtcgacacg tttacctagc aagttttgac
    26821 ggaaacgacc ttgtttccct ttcaacatat gagaaagaga tttcaatggg cggttacctg
    26881 gtccagtaac tggacgtccg cgacgaccgt tatcgatcaa tgcatctact gcttcttgca
    26941 gcatacgttt ttcattttga acgatgattc caggtgcatt caagtctaac aaacgtttca
    27001 aacggttatt acggttgatt acacgacggt aaagatcatt caagtcactt gttgcaaaac
    27061 gtccaccttc taattgaacc attgggcgta aatctggtgg aataacaggg ataacgtcca
    27121 taaccatcca gcttggttga tttcctgaag cgcggaatgc ttctaaaata tccaaacggc
    27181 ggattgcacg tgtacgtttt tgtccttgtg cagatttcaa ttcttctttc aattcggctg
    27241 cttctgcatc tagatcaaca ttatcaagta attgtttaat cgcttctgca cccatagcag
    27301 cttggaattc ttgtccatat tgttcacgtt tttcgcgata ttcgcgttct gtcaacaatt
    27361 gttttttctc taaattcgta tttcctggtt cgatgactac atatgaagca aaataaatga
    27421 tttcttccaa agcgcgtggg ctcatgtcta atacaagacc catacgtgaa ggaatccctt
    27481 taaagtacca gatatgtgaa acaggagctg ctaattcaat atgtcccatg cgttcacggc
    27541 gaactttcga acgagtaact tccactccgc atcgatcaca aacgattcct ttataacgga
    27601 tacgtttgta ttttccgcag gcacattccc agtcttttgt aggaccaaaa atccgctcac
    27661 agaacaaccc ttcgcgttca ggttttaagg tacgatagtt aatcgtctca ggttttttta
    27721 cttcaccgta agaccagctt ctgatttttt cgggagaagc caaacctatt tgcatacttt
    27781 cgaatttatt tacatcgatc aaaaggggtt ccctccattt catttaatgg caaaccgcaa
    27841 gacggctgat cttcgaccgc cttgcagctc atagaccgga ttagtctaaa ttatcttctg
    27901 cggtttcaaa gttttggatg acatcgtctt tttcatcttc cacttgttca gcagctttct
    27961 tttctaattc tttggcagtt tgctgttcgg caaattttgt caaagcatca acagtgatca
    28021 aatcgtcgtc ttcatcgtcc atgtcgcgaa gttcgatctc tgtttcttcg atatccaaga
    28081 cacgcatgtc cagacctagt gattgcaatt ctttcaccaa tacgcggaat gattccggta
    28141 cacctggttt tggaattggt tcacccttga cgattgcttc gtatgttttc acacgtccga
    28201 ctacgtcatc tgatttgtat gtcaagattt cttgtaaagt ataagccgca ccgtaagctt
    28261 ccagtgccca tacttccatt tcaccaaaac gttgtccacc aaattgagct ttacctccca
    28321 atggttgttg tgtaaccaat gagtaaggtc cgattgaacg tgcatgcaat ttgtcatcga
    28381 ccatgtgagc aagtttgatc atgtacatca caccgacaga cacacgtcca tcaaatggtt
    28441 cacctgtacg tccgtcgtac agaacagttt tcgcatcgct ggccataccg gcttcacgaa
    28501 ctgtttccca tacgtcttca tcacttgcac catcaaatac tggcgttgct acgtggatac
    28561 ctaactgacg tgcagccata cccaagtgta attccaatac ttgcccgatg ttcatacgtg
    28621 aaggcacccc taaaggattc agcatgatat cgattggtgt tccatcaggt aggaatggca
    28681 tatcttcttc cggcataata cgggatacaa cccctttatt tccgtgacga ccggccattt
    28741 tatccccttc atggatttta cgtttttgaa cgatataaac acgaactaac atgtttacgc
    28801 ctggtgacaa ttcatctcca gcttcacgag taaagatttt cacatcgtga acgataccgc
    28861 cgccgccatg tggtacacgt aatgatgtat cgcggacttc acgagctttt tcgccaaaga
    28921 tcgcatgcaa tagacgttct tctgcagata attctgttac cccttttggc gtgactttcc
    28981 ctacaagcaa atcgccatct tggacttctg caccaatacg gatgataccc atttcgtcta
    29041 aatcttttaa tgcgtcttcc ccgacattag ggatttcgcg tgtgatttct tcaggtccta
    29101 attttgtatc gcgggcttct gattcatatt cttcaatatg gatagaagtg tatacgtcat
    29161 cttttaccaa acgacggctc atgatgatcg catcttcata gttgtaccct tcccaagtca
    29221 tgaaaccaac taaaacgttt tggcctagag ccatttcgcc ttgttccata gatggtccgt
    29281 ctgccagagt atcccctttt tcgactttct cacccaaatg aacgattgga cgttggttgt
    29341 agcttgttcc ggagtttgaa cgacggaatt ttgttacatc gtatttatct aatgcaccgt
    29401 tgtcgcggcg tacgcggatt tcagaagcat caacgtattc aacgacaccg tcatgtttac
    29461 ataacaaagc agctcctgag tcatgcgctg atttgtattc cataccagta ccaacccatg
    29521 gtgcttgagg attgatcaac ggcactgctt gacgctgcat gttggcaccc atcaaggcac
    29581 ggttggagtc atcgttttcc aagaaaggaa tacatgctgt cgcaacggca actacttgtt
    29641 taggtgatac gtccatgtag tctactttat caatagatac ttctaagttt tcactttgag
    29701 cacgagccat aacaacgtct tgagcaaatg ttccatcttc attcaatggg ctgtttgctt
    29761 gggctacgat gtaatggtct tcgatatcag ctgtcaagta gtcgatttgg tcagtaacac
    29821 gacctgtttc acggtctaca cgacgataag gtgtttcgat aaatccgaat ttatttactt
    29881 tcgcataact ggacaaacta ttgatcaacc cgatgtttgg gccttcagga gtttcgatcg
    29941 gacacatacg gccatagtgg gagtagtgaa cgtcacgaac ttcataaccg gcgcggtcac
    30001 gagtcaatcc gccaggtcct aaggctgaaa gacgacgttt gtgtgtcaat tcgccaagag
    30061 ggtttgtttg atccatgaac tgtgacaact gagaagaacc aaagaattct ttgatacttg
    30121 ccacaactgg acggatattg atcaattgtt gaggtgtcaa tgtttcagta tcttggatcg
    30181 acattctttc acgaaccaca cgttccatac gtgctagccc gatacggaat tggttttgta
    30241 aaagttcacc gactgaacgg atacgacgat ttcctaagtg gtcgatatca tcgacattgc
    30301 cgataccttc catcaagttc aagaaatagc tcattgaagc aatgatgtcg gctggacgaa
    30361 ccgtttttac agctgcttct ggatagccgt ttccgatcac gtttacttca cgttcagggt
    30421 ctcttggtga aaatactttg atgacttgga cagtcattgg atctgtgacc acaccgtctt
    30481 ctgatggata gtaagtcact gaatttaggc cattatcaat gaaaggagct agtgtttcca
    30541 tgacttggtg agtcagaact gttccttttt caacgatgat ctcgcctgtt tctggatcaa
    30601 ctaatgtttc agctaatgtc agattcaata gacgtgtttt caaatctaat tttttgttta
    30661 ctttgtaacg accaacgttt gctaagtcgt aacgttttgg atcgaagaaa cgagcattca
    30721 gcaagttacg tgagctgtct gctgtttttg gttcgcctgg acgcaaacgt tcgtaaacgt
    30781 ctttcaaacc ttcttctgtt cttgagtcgc ttgcgttttt atgcaagtct ttttcgactg
    30841 tattgcgtaa tgtttcgctg tcgccgaaga tttcaaagat cgtatcatcg gaaccaaatc
    30901 ctaacgcacg aactaatacg gttaaaggaa tcttacgtgt acggtcgata cgtacataag
    30961 agatgtcttt tgcatcagtt tccatttcta gccaagctcc acggttaggg ataacagtag
    31021 aaccgaatcc ttcttttccg tttttgtcga cttttccatg gaaatagaca cctggtgaac
    31081 ggactaactg agaaacgatt actcgctctg ccccgttgat gatgaatgtt ccttgttctg
    31141 tcattaatgg gaaatcaccg aagaatactt cttgtgcttt gatttcgcca gtctcgcggt
    31201 ttgtcaaacg caatgttaca tgtaatggtg cagagtagtt tgcatcatgc gcacgagctt
    31261 ctgctactgt atactttggt tctttcaatt cataatctac aaattccaaa gatagattgc
    31321 cattgaagtc atcgattggc aaaatgtctt caaacatttc tctaagtccc tcatctaaga
    31381 accattggta agagtctgtt tgaatttcga tcaaatttgg taattccaac acttcactga
    31441 ttcttgcgaa acttctacgt tcgcgatgtt ttccgtattt tactacgtgt ccagccaagc
    31501 tcttcacccc tctaaaatgt cattcaaaaa gactacccga tcaattgtta caataatatt
    31561 tcaaatatta tttttaggta acaacagaca ttttttgcgg cttttaggca aaaaaaaacc
    31621 aaaaatagaa cattctcttg aaaccttact tcgtgagctt ctacttttgt ttccttatat
    31681 taaagccgaa acggacaata tttcgtttct gccttttctt catcagatag tttttgcaac
    31741 ttcatatact acacttattt tctataaaag tcaacacttc ctggcgtttc ttctgctttt
    31801 tcgcaacatt ttcttaatgt tttcaatttt atgttttcaa ttatctgaca attcttaatt
    31861 gacagacctt tttatctcgg ttatacttta gaaaattcat tttgtggagg aacttctatg
    31921 cgaaccaaca tcaaccaaat cgcaccaaca caactgaata acttttactt tagctacttt
    31981 agataggttt gtattcatca tgatggatac aaacgttaaa cgacagtttg tatctatgat
    32041 ggctaaagaa ctttgtattg cagcaaaaag ccacgtagac aaaatgctaa gtggctgagc
    32101 agtgaaaata caaagtaaaa gtatcaagca ttctactttt tcaatttatt ttccgacttt
    32161 tcaatccatt tggacatttt gtctgaatgg attttttgtt tcccaaaatt aaggaggaaa
    32221 aagaaatgaa aaaaaatata atcatcggat taggcgctgc cctgctacta gctttaggag
    32281 gttgcgcaca aaaagacaat tccgcagagg catcagatgg acaaaaaaca attggcgtat
    32341 tgcaacttgt acaacataac tcgttagatg ctgcctataa aggattcaaa gaaggattag
    32401 cagaagaagg gtataaagaa ggcgataatc taacaatcga ttatcaaaat gcccaaaaca
    32461 atcaagacaa cctgaaaagt atgagtgaga aactcgtcaa agaagatcct gatttgctac
    32521 ttggaatcgc cactccagca gcacaatctt tattaaatga aacaaccact atcccgatga
    32581 ctgtcacagc ggtcacagac ttggaacaag cccatttagt cacatccaat gaaaaacctg
    32641 gcggcaatgt gactggcacg acagatatgg tgccaatcga aaaacaaatc ggcttactgt
    32701 taaatatcgt gccagacgcc aaaacaatcg gcatcatgta taacaacggt gaagcaaact
    32761 ctaagatcca agctgatttg gcagaaaaag aattgaaaaa agcgggcgtc aaagtcaaag
    32821 tactgacagc aaattccaca aatgatgtcc aacaagtgac gaaaagtcta gctaaagatg
    32881 tagatggaat ctatattcct actgataaca cgttcgcaag tgcggcaagt gttgtcggtg
    32941 aagtcgcaaa agaaacaaaa acacctgtcg ttgctggcgc agttgatcaa gtcaaagacg
    33001 gcggtctagc aacagtagga atcgactacg aaagcttggg taaacaaaca gggatcatgg
    33061 cagcaaaaat cttagacggc aagaatccaa gtgaacttcc tgtcgaaaca gcgaatgatt
    33121 tggaactgta tgtcaataaa gacatggcca aagcattagg catcaatcca gacagcatca
    33181 aagaagctga ataaaacaca ggaggattct catgacaaat ttgctctctc ttttcttatc
    33241 atctgcatcg caaggggtct tatgggccct acttgcgatt ggtgtatacg tcactttccg
    33301 tatcttggac attgccgact tgactgctga aggaagcttt cctttaggtg cagggatcgc
    33361 ggcagtaagt attacaaatg gctatcatcc attgacagct tgtcttctag gctttttagg
    33421 gggtgcggca gcagggcttg tttccggact gcttcacaca aaattgaaaa ttcccgccct
    33481 tcttgcaggg atcatcacca tgactggttt atattctgtc acatcccgtg tgatgggtgc
    33541 gccgaacatc tctttattgg gtcagccaac gatctttcat tgggtcgagt cattcggcat
    33601 aacaaaagac aacgctgtac tgatcgtcgg tctgcttttt gctttgatcg ttgtatgttt
    33661 acttgttttg ttcttacgta cagaaacagg acttgctatt cgtgcaactg gcgataatct
    33721 ggcaatgagc gaagcaaacg ggatcaacac agataatatg aagatcatcg gttatatgat
    33781 ttctaatgga tgcattgctc tttctggctc cttgcttgcg caaaacaacg gctttgctga
    33841 tttaaattct ggtattggaa cgatcgtaat tggacttgct tctattatca tcgcagaagt
    33901 tttgttacgt aaccagccac tatttctccg tctcttgact gtcgttttag gtgcggtcat
    33961 ttatcgtttt attttagcgt tagtcttcga actgaatgtt gaaccaagtg attcgaaact
    34021 tgcttctgct ttcgtgctag tgatctgtct ttctttcccg cagatccagc aaaaattcca
    34081 tttacctcaa aaaaagaaag gcggtagtgt caaatgaatg acgtcttaac attggaaaat
    34141 ctccatcata cctttgaaaa aggaacgatc aacgaaaatc atgtcctgaa aggcattaat
    34201 ctttccttag atcccggcga cttcgtgacg atcatcggtg gaaatggggc tggtaaatct
    34261 actttgctga acagcatcgc cggtacattt tctgtcgatc agggtcaaat tttattgaat
    34321 ggaaaaaata tcacgaaaaa atctgttgtc gaacgttcga aatccatcag tcgcgtattc
    34381 caagatccta aactagggac agccgttcgt ttaacggtag aagaaaatct tgctcttgct
    34441 atgaaacgag gaaaaaaacg cggcttcttc cgtggtgtca aaccacaaga ccgaacattt
    34501 ttcaaagacc agctggttcg gctaaatttg gggttggaaa atcgtttatc ctcagaaatc
    34561 ggtttgctgt ctggaggaca acgtcaagct attacgttat tgatggccac attacagcgt
    34621 ccagaactga tcttattaga tgaacacact gcagcgcttg accctgctac ttccaaaacg
    34681 gtgatggaat tgacagaaaa gctgatcact gagcagaatc tcactgcttt tatggtcact
    34741 catgacatgg aagacgcgat ccgctatggg agtcgactga tcatgctgca tcaaggaagg
    34801 atcgtcgtag atatccagca agaggaaaaa cagcagctca cagtgcccca attattagcg
    34861 ttgttcaaac aaaacagcgg cacggcatta aaagacgatc aagtactttt atcttcataa
    34921 tcagaaagag gatgggacaa aaaatgaacg cccaccctct tcttttttct ctttccttct
    34981 ttcgtttttg ctttatgtat caaccgttgt ttcttcgaaa actattttgt tctctccttc
    35041 ttcctgatag aatggatggg aaaggagctt gatgccatga caacgaaaga caaggtactt
    35101 caattattga aaaagacacc agattttctt tccggagaaa agttggcaca gcaactggaa
    35161 gtttcccgga caagtatttg gaaagccatc aaagaattgg aaaaggcagg ctatcgtttt
    35221 gagcacgggc ctacagggta tcgttacctg ccctctgacg tactagatgc aaaagaaatc
    35281 cagcaagagc tacggtcgtt tattcctgat ttgaaagtac aaacgatgtt gacttctgaa
    35341 tctacgatga aagatgtcaa actggcagca gctcaaggag attctgtttc gaagttattt
    35401 gttgctgata cacaagaaca agctcgtgga cgttttggac ggcctttttt cgctgaacct
    35461 ggacgaggaa tctacatgag tctcttgctc catccagaca aacggtttga tgaattgcct
    35521 caatatacga tcatcgcagc cagtgcctgt gtgaaagcca ttgaatctgt aaccggtcgt
    35581 tctgcttcga tcaaatgggt caatgatatc tacatggatg gaaaaaaagt ctgtgggatt
    35641 ttatctgaag cagtcagtga tatggaaagc ggcaggatca gtcatatcat cattgggatc
    35701 gggcttaatt tttctgttcc tcaaaatcat tttccagctg atctccaaga aaaagccatc
    35761 tctgtctttc ccgacggaca agctagtgtc acaaggaatc agctaatcag caaaatctgg
    35821 caagaattgt tcacttatct ttctcaccca gaaaaagcgt tggacttcta taaagaaaaa
    35881 tcattcgtat tgggaaaaac cgtgtcgttc aatcaaaaag gaacgactta tgtcggtctt
    35941 gcaaaagaaa tcggtgatca tggcgaactg atcgtccaaa caaatgaaca gaagatgagt
    36001 ttgtcttctg gcgaaatcag tctcacatct atccgtacgc aataattatc agatttcaca
    36061 aaaggacacc tgatctcata cagtgtcctt ttttctgaat tctcttcaaa agactctcct
    36121 tattctatca gctgacagtt tctctatcct ctagaaaaag gtattctaaa aatatctata
    36181 aagcatggta cactttcttt aaatgaatca atgcaaaaaa caagagagtc atcagtttac
    36241 acgatcaaaa gagatagcag gccgcttcct ttttcaatct tatagataga ccatgggtaa
    36301 cgataaaaac aaaaaagaac ttgcgactta ttttgccgta agttcttttt tagctagtgc
    36361 cttaatctct taatcccaac aaacgtctcg catagatcac ctgaccagag tgcatagcag
    36421 catcatcaat aatagaaacg agacgcattc ctcgtgtgac tggtggtgtc cagttctcgt
    36481 caattacttc atctagctcg gaaggttcca gccttcttaa gtaagaaata gcaaaatcag
    36541 cagctcctcg caagtatcct agcagatctt ctatttgatt agcttggatc tgctttgctt
    36601 gttccagact atgcttccaa tcttgttcgt tatctgctat cgtcatcgga aaccggcttt
    36661 cccagtcttg actatgccaa attggagaag ttcctgctaa atcagcaatc tggaaatcta
    36721 attctcgagc ggtatgccaa gccagccaag tcattgattt gatctgcggg gctctatctt
    36781 ccactggaaa acgattggcc tcctcaatag agacgccttc aaacaaacgt tcaaaccgat
    36841 cgtatgcccg atccacactc tcgcatagca tatctaaata atccatttat tttcctcctt
    36901 tttatttatc ctacttactt tttcctaatt ctaggatacc tacttatatg ttactacaca
    36961 cccttatttt ttacacttta acagtcacca tcatcaatag tttggagatt gaaagaaaaa
    37021 gatagtgtcg aactatcaat tgaacaagaa gcaacaatat gaacgtttca ttaatattct
    37081 ttaaataaac aatgattttt caaacgaaca gtttaagact aggagaaaaa gagtataata
    37141 ggaaaatgtt tgaaaggaaa ggaaggggaa aaatgaaaaa aagggcaagt ttactagtcc
    37201 tagttgcttt gttgttcaat atcttttcgt atggtgtggc cgtttcagcg gaaacataca
    37261 ttcctaaaga ccctgggaat atttataatg atctaactgg taactatggc ttgttaggaa
    37321 ttgctagtca attccacgta tttgctaaaa ataagacaac tgtgaatgca catacagacg
    37381 gaaatatagc aacacatgaa cttgatgcaa aaaataattt tggtacagag cttcatgaag
    37441 gtttattgaa ccaagaaata aattatatac aaaaaactga ttctttcgct aattcttcag
    37501 gcatacctac aggtagcaca agaatgaata aatttgtcgt tggcagtaac gtggatgtag
    37561 cacttcaaga tggtcatcct acagtcaatg gatccaggct tgatcactta actccagatg
    37621 atttttataa agatcgtgct gggcatgaat atattgattt cgagcaggaa tttgctaaat
    37681 tgaatgtagc agcaaatgat cttgcaacga tcactccagc taaaacatat actgctgcag
    37741 attttccaga catgaacaat cggacaatcg atttaactga tttatcagat accgggtttt
    37801 tattggtaaa tatcgatgca gaagtgttaa cgatgaatac gccacttcaa atcattaatc
    37861 caaatgatca agtagttgta tttaatgtca tcaacagttc ttctgcattg aacgtacagt
    37921 caccaatcaa atacaatgat cgttcaaatc atgaaacaga agatttttcg gatgcgaata
    37981 tctcttggaa ttttggaaat gagatgactg atttgacaat cagtgctcct tttcaaggaa
    38041 caatccttgc gcctaatgct actatccgca ttactcaaaa ccaagacgga acgattatag
    38101 gaacaaatgt gattttagat gcagctacca atcgttggga tcctaacgaa atatttatca
    38161 gcgacaatgg tacagatacg acagacacaa gcgacagtac agatacatct accacaagtg
    38221 atagctcaga ttcatcaact tcaagcgaca gtacagatac tacctctacc acaagtgata
    38281 gcacggatac atcagcttca agcgacagta caga
//
LOCUS       DAZKCH010000017        37148 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000017 DAZKCH010000000
VERSION     DAZKCH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.017"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..386)
                     /locus_tag="ACG84X_000905"
     CDS             complement(<1..386)
                     /locus_tag="ACG84X_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126802.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKIL"
     gene            complement(571..969)
                     /locus_tag="ACG84X_000906"
     CDS             complement(571..969)
                     /locus_tag="ACG84X_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFP9126803.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(966..1739)
                     /locus_tag="ACG84X_000907"
     CDS             complement(966..1739)
                     /locus_tag="ACG84X_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFP9126804.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1736..2419)
                     /locus_tag="ACG84X_000908"
     CDS             complement(1736..2419)
                     /locus_tag="ACG84X_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFP9126805.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2586..3473)
                     /locus_tag="ACG84X_000909"
     CDS             complement(2586..3473)
                     /locus_tag="ACG84X_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9126806.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3470..4339)
                     /locus_tag="ACG84X_000910"
     CDS             complement(3470..4339)
                     /locus_tag="ACG84X_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9126807.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4476..5762)
                     /locus_tag="ACG84X_000911"
     CDS             complement(4476..5762)
                     /locus_tag="ACG84X_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9126808.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            6035..6613
                     /locus_tag="ACG84X_000912"
     CDS             6035..6613
                     /locus_tag="ACG84X_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9126809.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6613..7542
                     /locus_tag="ACG84X_000913"
     CDS             6613..7542
                     /locus_tag="ACG84X_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126810.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7539..9275
                     /locus_tag="ACG84X_000914"
     CDS             7539..9275
                     /locus_tag="ACG84X_000914"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9126811.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(9338..10174)
                     /gene="pheA"
                     /locus_tag="ACG84X_000915"
     CDS             complement(9338..10174)
                     /gene="pheA"
                     /locus_tag="ACG84X_000915"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFP9126812.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(10171..10680)
                     /locus_tag="ACG84X_000916"
     CDS             complement(10171..10680)
                     /locus_tag="ACG84X_000916"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFP9126813.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10673..11968)
                     /gene="aroA"
                     /locus_tag="ACG84X_000917"
     CDS             complement(10673..11968)
                     /gene="aroA"
                     /locus_tag="ACG84X_000917"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFP9126814.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11981..13072)
                     /locus_tag="ACG84X_000918"
     CDS             complement(11981..13072)
                     /locus_tag="ACG84X_000918"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFP9126815.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(13089..14255)
                     /gene="aroC"
                     /locus_tag="ACG84X_000919"
     CDS             complement(13089..14255)
                     /gene="aroC"
                     /locus_tag="ACG84X_000919"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFP9126816.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(14257..15321)
                     /gene="aroB"
                     /locus_tag="ACG84X_000920"
     CDS             complement(14257..15321)
                     /gene="aroB"
                     /locus_tag="ACG84X_000920"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFP9126817.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(15354..16376)
                     /gene="aroF"
                     /locus_tag="ACG84X_000921"
     CDS             complement(15354..16376)
                     /gene="aroF"
                     /locus_tag="ACG84X_000921"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFP9126818.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(17035..18009)
                     /locus_tag="ACG84X_000922"
     CDS             complement(17035..18009)
                     /locus_tag="ACG84X_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFP9126819.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17990..19873)
                     /locus_tag="ACG84X_000923"
     CDS             complement(17990..19873)
                     /locus_tag="ACG84X_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFP9126820.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19891..22116)
                     /locus_tag="ACG84X_000924"
     CDS             complement(19891..22116)
                     /locus_tag="ACG84X_000924"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFP9126821.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            22231..23265
                     /locus_tag="ACG84X_000925"
     CDS             22231..23265
                     /locus_tag="ACG84X_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9126822.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(23332..24345)
                     /locus_tag="ACG84X_000926"
     CDS             complement(23332..24345)
                     /locus_tag="ACG84X_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9126823.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24423..24611)
                     /locus_tag="ACG84X_000927"
     CDS             complement(24423..24611)
                     /locus_tag="ACG84X_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFP9126824.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(25051..25179)
                     /locus_tag="ACG84X_000928"
     CDS             complement(25051..25179)
                     /locus_tag="ACG84X_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFP9126825.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(25182..26555)
                     /gene="rlmD"
                     /locus_tag="ACG84X_000929"
     CDS             complement(25182..26555)
                     /gene="rlmD"
                     /locus_tag="ACG84X_000929"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFP9126826.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(26666..27721)
                     /locus_tag="ACG84X_000930"
     CDS             complement(26666..27721)
                     /locus_tag="ACG84X_000930"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFP9126827.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(27731..29161)
                     /gene="gatB"
                     /locus_tag="ACG84X_000931"
     CDS             complement(27731..29161)
                     /gene="gatB"
                     /locus_tag="ACG84X_000931"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFP9126828.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(29158..30630)
                     /gene="gatA"
                     /locus_tag="ACG84X_000932"
     CDS             complement(29158..30630)
                     /gene="gatA"
                     /locus_tag="ACG84X_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFP9126829.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(30630..30935)
                     /gene="gatC"
                     /locus_tag="ACG84X_000933"
     CDS             complement(30630..30935)
                     /gene="gatC"
                     /locus_tag="ACG84X_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFP9126830.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(31041..33077)
                     /gene="ligA"
                     /locus_tag="ACG84X_000934"
     CDS             complement(31041..33077)
                     /gene="ligA"
                     /locus_tag="ACG84X_000934"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFP9126831.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(33094..35328)
                     /gene="pcrA"
                     /locus_tag="ACG84X_000935"
     CDS             complement(33094..35328)
                     /gene="pcrA"
                     /locus_tag="ACG84X_000935"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFP9126832.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            35483..37042
                     /locus_tag="ACG84X_000936"
     CDS             35483..37042
                     /locus_tag="ACG84X_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFP9126833.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT        10263 a         8066 c         6698 g        12121 t
ORIGIN      
        1 agaatctttt gctgacgtct aaaaatagaa aaagaatttt cgtcatctat ttgataacgc
       61 atttgttttt gcagttctgc tgcagtcaga tggatcttcc catcgtttgt atcgatcatt
      121 aaaccttctg gaaacagttc aaccactgct cgatcccaag attcaagaga aagctcgata
      181 taatctttta ctggtaattc caattctacc ttaaaaaagt gcaaaacagc cgacagccct
      241 tctgcttgat agatttctcc taatgttagc ccctctagat ggaactctgg tgaaaaatgc
      301 agcaatgttt tattttcctg caattgaaca tatagaaatg tagatcgctc aatcagagta
      361 tcttttaaaa caactaaaaa attcattttt ctcccccttt tttcatcatt tttaaaatag
      421 catattttga aaagaaagtc tgatgcttag agtagaattt cataaaaatt tactatttca
      481 taagtattca cgagaaaaat acaaacaaaa aagcggaaat aacgctcatc cgccttcttg
      541 tttgtgttta tttcctcttc aaacgcttgt ctatgattca gacttttctc tatcgttatt
      601 ttcatctaaa agttcttgca ttccgataat ttctcgatat tgatgaatct tagtgatacc
      661 aatgactttg tctacatcaa tactaaaaca aataccatta cctggaatat cgatgttgat
      721 gccttgacca atcgcatcca ttactttatt cgtcaaacta tcgggtacta atgtcaacac
      781 aatatctttt tctggcgaaa tgtccaaacc taaaaatttc cctgaatcat gtacaccaga
      841 acctcttcca tgtaagatcg ttccgcctgc tgcacctgct tcttttgaaa agtcgataac
      901 atcttcgccc attcctccgt caacgatcgt cacaatcatg tgaagattca atgctacaag
      961 atctttcatt tgctttcccc caatttttgc aatctttctt tttcgattct gtctttttca
     1021 tcttttcgtt tataaatata tcctagtact aaagtggata atattggtgt caatgcaatc
     1081 attgcaacca caccaaaccc gtcaatgatc ggatctcttc cttcaatttg tgcagcgatt
     1141 gccacgctca ttgataaaat aaatgtcgaa cacatcgggc ccgttgctac tccaccgtta
     1201 tcaaaagcca ttgctaaaaa gatcttgtcc acttttcgtc ctaaaataaa tgctagcccg
     1261 tatcctggga tcaagaaata ataaagagag aatccgacga gcaaacgcca catagacaat
     1321 cctactgctg cgccgatccc aattgaaatt accatcagca tgattttcga tcggattctc
     1381 ccctcgctca attcttcaac ctgtttgatc attacatgaa tcgccggctc agcaaaccct
     1441 actaagaacc ccattaaaaa gccaagggga accagtatat aattgtaagg caatcccgca
     1501 atagcactgc ctaaatgctg tcctaccggt acataagcca tattgactcc gtgcaggaaa
     1561 aggatcaacc caatagtcgt tatcaagaaa cctttcataa tgtcaaagaa acgctttttg
     1621 cgcatacgaa aactaatgat attcattaaa acaaatagga ttacgatagg tgccactgcc
     1681 aaaatgactt ccatggtaac gatttcgatt ccatctatca cttgctgcca gaaactcatt
     1741 ggaagatcac ccccaaaatc atcacggcaa gaatcggccc taacgaagca ataccgacca
     1801 ttccaaaact gtcattttca tttttctttt gtttgatcat actagtcatc cctccggcaa
     1861 gggccaagat aaatggaaca gttactggac cagtagtcac tccccccgaa tcaaaagcaa
     1921 tcggcataaa ttcggaactg gtgaaaaatg aggcgatcaa aacgcctatg tagcctatag
     1981 ccatcaattg ataataggat agcttgaata cgacccgaag cagcgcaaag gctagaaata
     2041 ctccagtgcc gacgctgacg atcccaatca gcaacactct gccaatctct ccgtcagata
     2101 tatcatatac ttgttgtccc aaaacttgca cggaaggttc agcaatcgtg atcacgatcc
     2161 cgatagcaaa tcccaaactg accaaaacgg tcaaactttt ctttttgatc atatatttcc
     2221 ctactagatc tccgacttcc atcatagaat aatctgctcc aaacaaaaag agcgtcattc
     2281 cgatcatcat gattgccgca ccaaccagaa atgaagcgag gtcttctcct tctaacggtg
     2341 caaaaacaaa cgttaaaatg acaatcagga cagtcatcgg caatatagca gcaatcactt
     2401 ctttaaaatt ttttagcatg tatcctcctc ctttactctt taagtttacc ttaaaatgaa
     2461 agagttttcg agcacaaact taaaacgtta tcatttaatt tttctcaaca taaaataaca
     2521 cacgtcccaa aagtatcttt ttacttggaa aaatgacttt gaaggaacgc gcttattgtg
     2581 tttttttatt ttacagagcc gatcattcct tgaacgaatt gcttttgcaa aacaaaaaat
     2641 acgatggcag ttggtaaagt agcgatgact aatccagcca tgatcattcc atagtctggt
     2701 gtataggaag cacccatagc agataaaaca agcggaaccg tccgtttatc aggagattgc
     2761 aaagctacta agggccataa ataattgttc cagctactca tgaatgtgat gattgcagcc
     2821 gcggcatagg tatttttagc cgtcggcata tacactctaa aaaaaatact tagttctttt
     2881 agaccgtcta atcgagcggc ttctactaga tcttttggaa aagatttaac attttgtcga
     2941 aagaagaaga tcaaaaaagc agtgctaaca gatggcagga tgacaaccaa gaaactgttg
     3001 attcccaaaa ccgttccgtt caattgtgaa aacattcgat ataaagggat catcaatgcc
     3061 gcaaaaggaa ccatcatcga tagcagtaga atattgaaaa ttaggtcttt tcgtttactt
     3121 tgataaatct caaatccata tcctgccatt gacgaaatca gcaatgcaaa cacagtggtc
     3181 accaaagcga tcatcgctga attccaaagg gaacgagtaa aattcagctc attggaaaac
     3241 aaattttgaa aattgatgat caagttactg ccaatcttta tttttcccga tgtgatatcc
     3301 acgggtgtat tcgtcattcc caaaaccatc cagacaaaag ggaaaatgga aataaatgat
     3361 aggatgctta atgctgtata ctttaatact gacccaattg tcgaacgaag ttctaatgct
     3421 tgttttttga cgttggggcg ttcgattgtt tctttttcta ccatattttt catcgacttt
     3481 ctcctcctac tttcgtttgg attatcgaca atatcacaat aaaggaaaca ataacaaagg
     3541 aaactgctgc cgcatatcca aaattaggcg tgaatttata actcaaatta tagatgtatt
     3601 gagatagggt ggtcgttgca tttgctggtc ccccgccagt aatattttgt acttcatcaa
     3661 aaagctgcaa tgtcccgatc gtcgaagtaa tggaagtaaa caaaatgatt ggttttaaat
     3721 ttgggatcgt cactttgata aactgctgcc atttagaagc accgtcaata gatgctgctt
     3781 cataaatctc cgaatcaata ttttgcatgc ctgaaaggaa aaaaatcata ttgtatccag
     3841 tccaacgcca agtgatcgaa agaatgatca gaactctcgc ccaaattgga tgagtcaacc
     3901 agccaatcgg tgtgtcaatc ataccaatgc ccaacaacaa gttgtttaca aggccagatt
     3961 gagaaaatag acttttcatg atcagagaat aactgaccat cgaagtgata catggaagaa
     4021 agatagcggt tcgaaacaac cctttatatt tcaacttttt atcatttaaa aggttggaaa
     4081 taaaaagtgc tagaaacaac atgatcggta cttgtacaag taaatacagg aatgtattaa
     4141 aaaaagcttt tttaaaagtt gcatctgtca acatccgctg ataattacct aacccgttaa
     4201 atgtcatatt gacaggggga ccactttgaa aagacgtgat caaagccaaa accatcggaa
     4261 taaaaaccat gattgatatc aaaatgactg gcaagattaa aaaagcatgc ccgtttttga
     4321 ataaatcttt ctgcttcatt cttttccctc caattctatc attgattatc tacatgaaaa
     4381 gacaagaaag acaatatctg taaggcagac gtgatctttt ttgtcttttc gtttgtctga
     4441 tgaaaaagcg aagaaattca cttttttacc accgatcaat tagccaattg tgcttctact
     4501 tgtttttgtg tatctgctag taccttgtct gtctcttctc cattgatgat tcgatgaaga
     4561 gcttcagcta cgactgcttc aattgcatag gtctcatgtc cgtaattcac ttctggtatt
     4621 tcagatgtcc atgttgaaaa atcgtcaaag atcttttgac cactgtaaaa ttcagaagct
     4681 tcttgataag cttcttgttc attcgcgcta agcatcgtag atactagtcc gatttctttc
     4741 gcaagagtgc ccatcagttc ttcattcgaa gcaaacgttg cttctaggaa atctttcgct
     4801 gaatcttctc cagctactcc tttgatcaca taccagccag cgccgccaag gttagaagct
     4861 tgcgcttttt gcagattttc tggaagtgca ggtattggtg caatcttcca ttttccagat
     4921 tggttttctg ctccttggat cgttgaagaa taccaagcgc cagttgggct agaagctact
     4981 gctcctgatt gtatcgcagt tactccagca ttccagtcag aggtttgttc gactagatct
     5041 tctttcaaaa gagtggcaaa caattcaaga ccatacttta aagatgcatt gtcttggatc
     5101 gtgactgtct ccccatcttc agatgtatac cattctcctg cctgttgcat aatcatcctt
     5161 actcgaccaa ggtcagaagg attgacttca gcgattttct ttcccgtctt ttctttgaca
     5221 tctcgcgcta cttgaatata ctcgtcccac ttcagattct ccatatcctc ttctgtataa
     5281 cctgcttctg ccatcagatc cgtacgatag aagtttgctg ttacgcccga atcgaaagga
     5341 acaccgtata ttttatctcc tactttgttt accgcaaatt tatacggtgc aaaatgatct
     5401 tcctttacaa tagcagacaa attagcgaat gcatctggat aagaagtcaa atagccttgt
     5461 atcctataat cttcaatcaa gacgatattg ggcaatcctt ctgtattccc gctcgctaaa
     5521 gcggtgttca gtttctgaac gatatcatcc tgagacatcg taacaacttc tatctctgtt
     5581 tcttcgttct cataaacttt ttttgcttca ttcactgctt tgatattgaa tgtctcatcc
     5641 cacgcccaga cagtgacttt ttcttctttg tctgctgtac tactagcact tccgcatcct
     5701 gttaagaaac ctgatgctgc cgctaaacaa acgactccag caattaactt tctgatgttc
     5761 atttttatcc gctccttttc catccattag ttgtttacgt ttgctacatt catcatacca
     5821 aaatttgaaa acggtttctt tattattcag atacttcaaa aatttctcct aaaataataa
     5881 aaaaatacaa atcaactatg acaaaaggaa taatcttagc atctagacca aagatcgaaa
     5941 tggtgaggtt tctttaaaat aaaaatatcc ttgcattttc tcctagaaat aagtattttt
     6001 aaattacaag actattctta aggcgggtaa aaaaatgcca atacgcgtaa ttcttatcga
     6061 tgatgaacag acgattttag atggaatgaa acagttgatc aattggtctg agcacgggtt
     6121 tcaattaata gggacttttt ccagtccgct gaaagcgctt gatttttctt tggtacatgc
     6181 aatcgatatc gtggtcacag atgtaatgat gcctgaatta aatggaatcg aattatcgcg
     6241 gctattaaaa cagcaacaac ctgaaacaca gatccttatc ctctctagct atgatgaatt
     6301 tgatatggtt aaagattctt ttaaagaagg cgtcgctgat tatcttttaa agcctcgatt
     6361 gagtcctgat ttttttctaa attccttaac tgccgtttca caaaaaatca aaaaaaagcc
     6421 caacaaaagc ccaatcacca atcgttatga gcagatctgc gagaatcttt cacagcagat
     6481 tgctggacaa actcgtccat tgcttgaccc tcttcttttt gaacacacct tgtttttctg
     6541 ttatataccg aaaaacggcc attcagttca aaacaaggct ctaaacaaaa acagtcgatc
     6601 acccattcat tgatggatag cgacgattcg tttactattt atcctgtttc taccttttcg
     6661 gaagaatccg gctatgtaat caatactgat tccaaagata cacttaggaa gtttgttcaa
     6721 aagtttcgtc aagaagtttt tccaggtgat ttttttgttg tttctgattc ttttgcaatc
     6781 caagatatca atgaaatatt ccaagagatc agaaattgca ccaaaggaca acgtttctat
     6841 cataagggaa agaaccttgc ttatcagcat gaacttcttc cgttattaac caaccacgag
     6901 cagcaagcaa gtagttattt aacaaaaatc gttcataaag actacgcttt agctgtcaaa
     6961 gaacttgaga atttcttcac gacgatattg gaacagccta ttgatccagc ttatttgaaa
     7021 catgaggcaa tcaatcgttt ctatgcatta ctcaacgctt tggctgacga gcatgttggg
     7081 aatgaagaac tttctttgct caagatcgcc cttccttctt tattagccga tgctgagtat
     7141 ttcgaagatt tttctattct tgtcaaagaa acacttgaga aactcaccca cttttctgca
     7201 aatgcaaaaa aagacaattt cgatatcttg actttgatct acgagttcgt ccaggaaaat
     7261 tatgagaaag aaatcaattt acaactttta tccgaaaaat atcatttttc atatagctat
     7321 ctctcagcca tctttactga aaaatttggt atcaactttt caaaatatct aaaaaaagtc
     7381 cgtatcagta aagccaagct ctttttgacg gaaacacggc ttactttgac ggaaatctgt
     7441 gagaaagtcg gctataccga actgggttat ttctccagag tttttaaaga agagacagga
     7501 atgacacctt ctcaataccg taaaggaact tttgtaaaat gagaaaaaaa atcaaagagc
     7561 atgaactctt tgccaaactt ctgttcattt tgttcatcgg tctttttctg caagccatcg
     7621 tcatttcttt gtttatttat catcgatcaa gggatgccta tatccagctg ttcaatcaat
     7681 cgaatgatgt ggtactaaaa aagattcaat ctgaatttga aagtttgaat gatacaatcg
     7741 agaatacatt agccgctttt gattctaatc cagctgtcaa aagctatttt tccaatgatc
     7801 cagcccaaca tatggaacag cttcagcaac taagaacaat ccaaaaaatg aatgactctc
     7861 tttcaaaaat ccatccaatg atcgattacg atgtattgat ctttggagaa aatggaagaa
     7921 cttttgtcgg aaacgacatg ctcactgccg tatctgccga ttcttttttt caatctgcga
     7981 ttgctcagag agtgaatgaa cgtgctgctg atacacaaat gctttttgca caccacggat
     8041 tgactcttcg cgataagaaa gcacccagcg tcttctttgt caaaaaactg aaaaatacat
     8101 tgaatcacgt ttacggatat gctgttttat cgatctcatc caagcaacta gcgaatcttt
     8161 ttcaatctgt agtaaatcct gagatatcga agatctcctt catgaacgaa gaacagacga
     8221 tcatcgcatc aaatgaagaa aatacaattg ggagccgatc aatgattttc aaaaaactaa
     8281 cagtaggtga aacaacgatt tcaaatggac agcagttgac ccgtcttcct ctgtaccgcc
     8341 aggattgtac attactcagt caagtcgatc ttcattcttt atctaaccaa atgggcgtga
     8401 tttttccgat tattttgtat aatatcgtga cacttgcttt tgctggctca ttggtattta
     8461 tgtatttgga tcgacacaca aaatcgatct accgcttgat tgattcgcta aaacggctag
     8521 aggaagatgg cttaaaagct actgttcctg tacaaggaag ccatgaagtc caattgctag
     8581 ggaatacgat caatcaattg ctaagtaatg ctcagcatca ttatgaacag acgatccaag
     8641 acgaaaagaa gaaacgttcg cttgaaatcc aaactatgca agcacagata cagccccatt
     8701 ttatttataa tacgctgact agcttgaaat ttttgatttg gcagaaaaaa acagatgaag
     8761 cagttcaagg aatcgacagt ttcattactt tactaagaag tacgattggg aaaaaagaag
     8821 aagtgattcc agtcaaggaa gaaatcaaaa gcgtacaaag ttacatcgat cttttgagta
     8881 tgcgatatgg cgaaagaatc tcggctaaaa taatgattcc tgatgaactg cagtcattat
     8941 ctatgccgaa tatgatcctt caaccaatta tcgaaaacgc ctatcttcat gcttttcaca
     9001 ataaaacgca aggattcatc acggtgtacg gcaaaacaaa aaatcagctt cttttattcg
     9061 aagtgattga taacggcgat ggcttcgata ctgaaaatac caaacaaaaa aatgatcatt
     9121 tttcaggaat cggcatcagc catgtagatg agcggatacg cctaatgtat ggcgatgcat
     9181 atggcttaac gatccaatca gtgattggga caggaacgac tgtaacgatt tgtctaccgc
     9241 ttcttcctaa aaatcaatca gaatatcaaa aataaagaat agccaagcgc tgattttttt
     9301 attttaagtt aaataaatca atcagtattc ttgactttca tctacgcgtc tcttctactg
     9361 tcagcactgg ataacagccc aatatttgac tttctcctcc gagcatcttg atttcttgga
     9421 gcgcattctc tactaatgtc attggacggt ccaacaacaa atcgatcacg aaaaaatatt
     9481 ctcccaagct agttttcaat ggtcgggatt caatcttact taagttgatt tcccgccagc
     9541 caaaagctgc cagcatttta tgaagcatcc ctggccgatt agcaggtagt gtcaagatga
     9601 cactcatttt tactggagct gactgctggc tggtcatctt tcggtcaccg acgatccaaa
     9661 aacgtgtctg gttcaactca ttatcttgga tattctcagc taagatctcc aatccaacat
     9721 gctgtgctgt ttctaatgaa gcaatcgctg ctgcgtcttc tttcggatgt tctgctacat
     9781 acattgctgc agcagttgtt gattctgttg ctactaaagg aacattagga taatgcgttt
     9841 ctaaaaactg ttgtgattgt gctagtgctt gtggatgtga aaggattttt gtaatctttg
     9901 ttgctggatt gcctaaaagc tgctgcttga taggaagaac gatttcactt ttaacttcga
     9961 cttctggatg tttggaaaga agatcgattg tgtgatgaac agctccttcc aatgaattct
    10021 ctacaggaac gacagccaga tcgacttgtt tgcgaaacaa agcgcgcaaa caaacaggga
    10081 tggaagcata cgcagtcaat tgttctgtag gaaatagctg acaagccgcc tgataagtga
    10141 atgaactttc tggccctaga tagctgacgt tcatatgctt ttgatccttt ctataatggt
    10201 atcgatgatc ttttctggtg tttgattggt cgtgttgatt cgatgtgtcg cactttcttc
    10261 ataccaagaa agtcgttgtg ccaataatgc ttttatttct tctcttgttt ttccaagagc
    10321 taaaggtcga atagacgttt catcttgttg gatacgatca actagacagt ccgcttctgc
    10381 ctctaagtaa agaacaatcg gctgtgtttt taaaaaacgc cgattttctg cactttggac
    10441 aatccctcca ccagtcgcga taattttgtc ttcatttgac agctttctta aaatatctga
    10501 ctccactttt cgaaagcttt tttcaccgta atagtgaaaa tattcggcaa tcgacaattg
    10561 gatatgttcc tcaatctttg tatctaaatc tacatactct ttttgtaaac attgagctaa
    10621 ccctttaccg attgttgttt ttccagcgcc catgaaacca atcagcaaaa tgctagccat
    10681 gagcttctcc tcctgacaca agttctgcta aatcgtcaaa aaatgccgga taagagattg
    10741 aaacagcttc agctccttct agttcgcaag gtccatcagc tatcaaagca gctacttgca
    10801 gcatcatacc gattcgatga tcgcctctgc tggacacttt tgcgccatgc agaggtgtcg
    10861 gcccatggat gatcagaccg tctgctgtcg cttttatctt tgctcccatt ttctgtaatt
    10921 cttctgccac cgcatcaatt ctgttggttt cttttacttt taattcttct gcgtctttga
    10981 tgatcgtgat tccttctgct tgagtagcca ctaaagctag aatgggcaat tcatcaatca
    11041 gacgcggaat gatttctcca ccaatcgttg ctttcttcaa atgactcgtc ttgacactta
    11101 aatcagccga ttggttctgt tcattgtgat tcgtctgggt aatcgctgcg cccatctcct
    11161 ccaacacatc taagatacca gttcttgttg gattgacccc gacatttttt aacaacagtt
    11221 ggctttccgg aacaagaagt cctgctgcta gaaagaaagc agctgatgaa atatcacctg
    11281 gaacagttat ctgttgacca gttaattttt gcggtccggt cactatgatc gttttatctt
    11341 ccactgtgat ccttccgcca aattgacgaa tcatttcttc cgtatggtta cgggaacgtt
    11401 ctttttcaac gattacggat gtgccttctg cttgtaatgc cgcaaacagc aaagcagatt
    11461 tgacttgcgc actggctaca ggcatattgt atcggatagg tgataaagag cgggttcctg
    11521 tcacagtgat tggtagatac tggtcatttt cttctccttg caagtcagcg cccatctcgc
    11581 gtaaaggttc catcactcgc cccattggac gtttagacaa cgaagcatcc ccgaacagag
    11641 tagtcgtaaa aggctgtcca gccaaaatac ccatcaataa acgtatggtc gtaccggagt
    11701 ttcccatgtc aattgattcg gttggttgga caaatgagtg gctaccgcga ccatgaatct
    11761 tgatcacctc ttcctcttct tcgatctcga cacctaattg ttggaaggca tgtaaagtac
    11821 tcagacaatc ttctgcgcgc aaaaaatttt gtatagtcgt cgttccttca gcaattgctc
    11881 caaacatgat gctgcgatgg gaaattgatt tatctgctgg tatcctaaca gtccctctta
    11941 atccatgtat ttgttgtaat aattgcattt atccagcctc ctatttgatc cagcaatgat
    12001 aactggtatt agacataatg attctttttg cttgtaacaa atcctgttgg tttttaaaac
    12061 tgatttgcag tattcctaaa atatcttccc tggtctcttg gatcttcaaa ttaatcaaag
    12121 aaactcccgc ttttccgatc agtccagtta cttctgcaat aacgccaggt tcatctggca
    12181 catcgataaa taaatcaaaa aaggcaggaa tcgcgccttg cttatggaca ggcaactggt
    12241 ctcgactttc ttttgcccga ttgaaaaaag aaaagatttc cgattggttc tcagtcatga
    12301 tccattctgc tatttgtgtc atttcttgtt gccaatctgc caatcgttcc aataatatct
    12361 gcttattgct caacaaaata tctgtccaca tgacaggatc tgaggaagcg atcctagtga
    12421 tatctcgaaa gcctcctgct gccagttgtt tggctcgcgg atactcttga ttgaattgtt
    12481 ctgcctgatt gactaagcca gctgccagaa tatgtggaaa atgacttagc attcctgtta
    12541 tacggtcatg ttctcttgct gtaagagtta catattttgc tttggttccg caaaatagtt
    12601 cttgcagttt ttcaacatct tttttcgtct tttccaaagg tgtaaagatg taataggcat
    12661 tttcaaatag tttagcatct gctgcctgta tacctgattt atgagaacca gccattggat
    12721 gtccaccgac aaaccgaaga tttttctgct cagcggatgt cacgacttgc tgcttcgtac
    12781 tgctgacatc cgtaatgatg acgtgatcag acaagttgat tctttcaagg acatcaagat
    12841 aagctaaggt tgtacggacg ggaacggcta ataagataac gtctgcttgt tctgcacctg
    12901 tttcaaaatc acttgcaacg taatcaacga tctgctgttc tactgcttgc tcacgggttt
    12961 ttgactgact atcccaacca actactatca gttctggatt ggtctgacga atacaaagtg
    13021 ccatagaagc accaatcagt ccaagcccca cgataaaaac atgttgtgcc atcttatttg
    13081 cccccttttt agtaatgttt caagtagtca cggtactcct tcactgcagc tttcaactca
    13141 acaagcgaat cacttgggaa ttttgacaat agctctgtcg ctaccacagt ggctacaaca
    13201 ttttccgcaa cgacgctagc tgcaggaact gctgtactat ccgaacgttc tacacttgct
    13261 ttgtaaggtt cttttgtatc gatatcaaca ctttgaagtg gcttgtacaa tgtaggaatg
    13321 ggtttcatga ccccgcgaat gacaagtggt tcgccattgg tcattccgcc ttcgaagccg
    13381 cctagattat tggtacgtcg gaaatagcct ctttcttctt cccataggat ctcatccatc
    13441 acttctgagc ctggtaatga accagaagtg aatccgaccc caaattctac gcctttaaag
    13501 gcattgatac taaccacagc ttgtgcgatt ttggcatcta gcttcgtgtc ccattgtacg
    13561 tagcttccta atccagctgg aacgcctcca acgagcactt ctacaattcc tccgatcgta
    13621 tctccatttt tctttgtctg atcgatcaaa tcttttattc tttgctcaac tgctggatca
    13681 acaactcgta cttctgacgc ttcagaaatt tctttgattt cttgaatcga gatatttcca
    13741 ggtatttctg cttggattcc accaagacaa atcacgtgtc ctgctacgat gatgtcaagt
    13801 tcttccagaa ttttcttggc aattgcgccg attgctacac gcatggtcgt ctctcttgca
    13861 gaggaccgtt caagcacatt ccgaagatct cgatgatggt atttcatacc gcctaccaaa
    13921 tccgcgtgtc ctggacgcgg acgtgcaact cgccgcagtg attggtcttt ttcaggcact
    13981 tctgctacag acatgacagt tgtccaattt ttccaatctt tattttctac cactaaagtg
    14041 acaggtgaac caattgtttt gccgtgacgg atgccagacg tgatccgaac acgatctttt
    14101 tcgatcttca tccttcctcc tctgccgtaa ccagcttgtc tgcgagcgag ttcgtgattg
    14161 atttcttctt ctgacagagg taatcctgct ggtagtcctt caataatggc tgttaattct
    14221 ggtccatggg attctcccgc agtcatataa cgcatcttac agtcctccta agtaatcttt
    14281 gaatgtctct gtgggaacag gaacgatttt tgcttgccca atcttttcta gcaagatgat
    14341 attcaattgg cttcctcttg ctttcttatc atgggttatc gcgtggaata attcatctgg
    14401 atgacttaga tcgtacgtaa tcggcagatg gaatttttga agtatccttt ctaaagcagc
    14461 tgtcgatcca gttggagaca agccgatttt ttctgcatga gaagtgatgg ctaccattcc
    14521 aatagctact ccttctccat gactgactac cccatatcct gctgtatttt caattgcatg
    14581 gccaattgta tgaccaaaat ttaaaataag tcgatttcct tggtcaaaga catcttcttc
    14641 cactactttt cgtttgattt ccaacgtagc agtaatgatt ggaacagcat gttccagaag
    14701 atctttttcg tctttcagct cgttcagctg tttccaaagc gttgcatctg ctatagctgc
    14761 tgatttgatg atttcagcga ttccttctcg taaacgacgt accggcaaag tttttagaac
    14821 ctcaggatca atcaatacac cagctggctg gctaaatgtt ccgacaaggt ttttcgcttt
    14881 gtttgtattg actgctgtct tcccgccaat actagaatct acttgtgcaa gtagcgtagt
    14941 cggaatttga acgaaatgga tcccacgcat gaacgtcgag gccacgaatg ctgctagatc
    15001 acccaccatt cctccaccaa gtgcaagtat cccatcgctg cgggtaaaat cattatctgc
    15061 taaaaaatcg tataactcag ctgcttgttc taaagattta ctggtctcac ccgccggtac
    15121 gattgaaagg actggttcaa aattagcttg tctcaattgg aacatgattt tttctgcata
    15181 tagtggagca acgtttgtat cagtgatcac agctactttt tgaggtctcc aaatcgtttg
    15241 aagccatgat ccagcctgtt ctagtgcgcc tttttcaata tgaatatcgt atttttggtt
    15301 atcaacatgt acagtaagca ttcgtttcac ttctttcttt taaaaagctg gaattaatcg
    15361 agtgtctgaa tcttttccat tgcttctttc atgatcgcaa cttctttcat catgcgtgag
    15421 taagtctttt cattcaacga ttggggaccg tctgaccaag catttgcagg atcaggatgg
    15481 atctctacga tcatgccatc tgctccgctt gccacacccg cacgagccat tggtggtaca
    15541 agttcccaaa ttcctgtacc atgacttgga tcaacaatca cagggaaatg agttaatttt
    15601 ttcatcaatg ggacagcact taaatcaaac gtattacgtg tcgctgtttc gtaagtccga
    15661 atcccacgtt cgataaaaat gacaggagat ttgtcttcga ctgcaatgta ttctgcagca
    15721 ttaagccatt cattgatcgt accggaaatt ccacgtttca atccaacagg tttacctgtt
    15781 ttaccgacag cagatagcag tttaaaattt tgcatattac gtgcgccaat ctgtaggata
    15841 tcgctgtact cagccaccat atcgatatgc ccttcatcca tcacttcagt aatcactttc
    15901 attccaaatt catcagccgc ttgacggatg tatttcaatc cttcttcttc taaaccttgg
    15961 aaagcatatg gagaagtacg tggtttgaag gcaccacctc gcagaatttt tgcgcccccg
    16021 gctttggcca ttcgcgcaca ttctctgatt tggtctaatc cttcgataga acaaggacca
    16081 gccatcgtca cgaaactgcc gtcaccaatt tttactccgt ctacatccac gactgtattg
    16141 ccaggatgga attctcgaga agtcaatttg tatgtgttta aaatacgcac agcattttct
    16201 actccttcat agcgtgtaaa tgctccttct tgtaaacttc gcgtatcacc ttttagtcca
    16261 atcactactc gttctgttcc ttgatcgatt gagactttga atccttcttt ttcgatatga
    16321 tcgacgactt tttttatttg ttcttccgtt gcttcttttt tcataattac tatcattgtt
    16381 tttcccgctt tcttttgttt acttatctat cttggctgat tttctctact ttttcaaggt
    16441 ggttttacat taattcctac taaatgaccg tgtcctgttg ttctcatttt cgctccttct
    16501 ttcctactta tgacccagat aatcaacaaa aaaagatgtc cctgtaggaa attgcctcta
    16561 cagtgaacat cttcaacgag ccttaaaaag cgctgcaaaa atataaaata gccactatag
    16621 atgaatttct ctacgtggct gtaagtcgtg tttaaaaatc tttagccatc atagatacaa
    16681 acctggtttg tttgtaccca cgaagtcatg aatacaaacc tatctaaaat agctaaagta
    16741 atacgtattc agttttgtaa gttttctaga tttcataaaa aatcgctcca aactgatgta
    16801 agaattgtac ctagtataga cataaaaaaa tcgactgtca atcattttta tgaaactttt
    16861 tttaattttc tgatagttaa ctttgttttt cagaaaaata acaattggtt ttattgaaga
    16921 aaatagtcat gaacaaaagt atctgagaac ttttttactc tcttgttcat gacatataga
    16981 ataaagcagc tttgtcttgt aaactccgtt tttcaaataa taatctaaag attgctactg
    17041 aataataaag ccgatttcat ggtcctcttc gctgctgatt cggtaaggtg actcaacatc
    17101 cgctccccag ctattgatac ccccgactcc tcttactttt gcaaaaatcg taagaaccgt
    17161 tcgtctttct ggcggtagtt cttctatatg tgttgcctgt tccagttctt ctgctttgaa
    17221 tggtaaagcg gaaaaagcaa atggcgtatc ctgctgttca aatcgcaacg aaaaatcttc
    17281 ttgatcttta tccgtattat ccaacgtttg atttcttgtt agttctaccc atttcgtttc
    17341 catatgcatg ccgcattctt ggggaacaag gtatggggaa acggggagtc ctgccacttt
    17401 ataaatacct tcgacaccac cagccatccg atccggatat gtttcccctg ataggccttc
    17461 atactcaaaa aattttgctt tcgttggcat aatgaacctt aaacccaatg cgggtaattc
    17521 cggtaatcct ttttgtccat aataatgcat attgacaagc attttaccct ctccagcgat
    17581 ttggtaggaa attgtcactt gggtttttgg tactgtgttg atttccagtg taaaaatgat
    17641 ttcaaccgtt tcagcgtatt cattacttga atattgatta tttactggag caatcggcaa
    17701 atcgatcttt ttattgtcca ccagtacttc tatttctttg acttttggat acaatccggc
    17761 tcctaaccac ataccggatt taaatccaaa tccgctacct ctgtcattat cggtcgttgc
    17821 tcgccaaaaa actggaagtg tttcccggta tagccattct tttccgtttt tattgagcga
    17881 ttccagtccg cctcttgtat aagaaaaaat ataatgcgta ttccccgatt tgacacctaa
    17941 tgtacagtcg ccgaagacga ttgcaacttt ttccgtatcc atatgacttt tatttactgt
    18001 atttttcata ataatatctt acctcctgca tggcgggttt ttcttgtcca tctgcaaaaa
    18061 cgatcccatt ccctgagaat tcatagtcac ttggtttatc gtcaaagtca ccgccatagc
    18121 gcatcacttc tctgcctgtg attggatcag tcacttggat cgcctgatct ttaaaatccc
    18181 atatatagcc tccttggtac atttcataac gatcaagcaa cgtcatgtaa gaatccattc
    18241 cacctaacga attccccatg tcatgcatat attcacataa gatgaacggt ttttccgctt
    18301 tattttcaag gtagtcaatg atctcttctg gtggcgcata catgcagctt tttacatctg
    18361 aaatcgaatc ttcgaatgct ggatttggaa aattcccttc ataatggaca agtcgatcgg
    18421 ggtctacttt tttgaagtaa tcgttcattt gtcgaatgtt ttcttccgca taagattcat
    18481 ttccaagaga ccaaaaaaga atacttggat ggttttttaa tgtttcgaaa ttcgtttttg
    18541 ctcgatcaag aacagccgcc tgccactgag gtactgcacc tggtacgttg taagaaggct
    18601 caaatgcgcc cattttttgc catgagccat gggattcgag gttcgtttcc gccatcacat
    18661 ggattcctgc ttggtcgcat aaataatacc aagtgatctg gttggggtaa tgagatgtcc
    18721 gtacgccgtt gatctttgca ttttttatga tagccaaatc tttttccata tcttctatag
    18781 tgatggcgcg tccttttttc ggatgccact catgtcgatt taccccgttg ataatcatcc
    18841 gttttccatt gaagtagatg attttatctt tgatttcgat tttacgaaaa ccgaaggaat
    18901 agtcaatata ctccgttact cttttttctt cgtctatcgt ctccaattca agcttatata
    18961 aattgggctg aaaatgcccc cacagtgcca cattttcaaa tccatcgatg cgaatcgtca
    19021 tttgctcttt taacggatat tgctgttgat agatttcctt cccatcagga tctagtatcg
    19081 ctacattcag ctgactgttt ttggctactt gctcaaaaga caaatctact tcaagtttgc
    19141 cattttgaca tttgtcatct aagcgaggtt tgatccaaag atcttctaaa tggttttgtc
    19201 ctcgagcaac taagaagaca tctctgaaga tcccaaaaaa tcggaaaaag tcctgatctt
    19261 ccaagaatgc agctgtactt cttttgtaaa cctccacagc tagaatattt tcttcttcca
    19321 aataaggtgt taaatcaaat tcagacggag tgaacgaatc ttcggcatac ccgataaaat
    19381 gaccattcaa ccaaataaac attgcttgtt ctacaccagc aaaatgaatc gagatttgtt
    19441 ttccctttag accttcttct aatcgaaaag tcgtcaaata cgaaccaacc ggattgtctt
    19501 tagcagctga aaagatccct tccgcctctt tctcagggct tgtcgtgaaa gggggacggc
    19561 gaaatacatg tccctcccac ggatacatcg tattgatgta atggatcttg tcataatttg
    19621 ctaattcaat atgactagga acagtgattt catcaaaaga acaggcatca aaatcttttt
    19681 tataaaatgt ttttggtcgt accgaaggat ttggcgaata acaaaaacgc catgatccat
    19741 ttaaagactg tttaagggag gatgtggttt ctacttcttc ccttgttgca taacaaacat
    19801 gatcgctatg tgcatttgat tggttcactc taaaaacttg tggatcatct aaccatttta
    19861 tatttgcttt catacttttt tccttctctc tcataacttt ttgaaatgaa gcagttctgt
    19921 ttggaaatca ccttgaaaat cggggaagta aagtccaact gtcatcaatt cggcccccga
    19981 aaatatccgc ttcgaggtct gttcctgata aagtgcctca tcatctaacc ccatcagata
    20041 tacttcatgg aacgctggtt gagctgaagc tagtatcctc cctaaaaaca caatagcttc
    20101 atcttgttta ggagacacaa acatccatgc ggcaatattt tcttcaaaag gactcgccaa
    20161 acgataataa tggccatact ggatcaccgg acgaatcgtt tgataggata taatttggtc
    20221 ttttacttgc ttttcttctt caggagacag ctttgtcaaa tccagttcat aaccaaaaac
    20281 agcgctcata gctgtttctc ctcttgtttt caacgaagta gatctgtcgg tctgatgatt
    20341 tggtacagct gatacatgag ctgtgatgga cgaaatcgga taagcaaggc ttgttccata
    20401 ttggattttc atacgctcca ctgcatccgt gttatcactt gtccatgact gcggcatata
    20461 ataaataaac ccggcatcaa accgtccacc tccaccagaa cagccttccc ataagatttc
    20521 cggataatca gttgtcaaat gttcaagtag ttcataaagc ccgagcatat aacgatgcgc
    20581 tacttctcct tgtctctgtg ggtcaagggt aatcgaatag acatctgaaa gcgaacggtt
    20641 catatcccat ttgatgtagt caagaggaat cgtatctaaa atctttctca tttgtttctc
    20701 aatcgtctgc cgaacatcta accttgtaaa atccagtaca tgttgtgatc tggaagcaga
    20761 aggcattcta cctggctcct gcataagaaa atcaggatgt gttcgataca gttcagaatc
    20821 aaccgagatc atttcaggtt caaaccataa accaaatttc aatcctttgc tatgagcata
    20881 atctgctatt tcacgtaatc catttgtcaa cttgccttca tactcgaacc agtctcctaa
    20941 tgaagaattg tccgcatctc tttttccaaa ccagccatca tctaatacga acatttcgat
    21001 gcctagctcc tttgcttcat caatgatcgc cttgattttt tcactattga agtcaaagta
    21061 agtggcttcc cagttattga ccagaatcgg ccgttcagca aattgatgac gacctcttgc
    21121 gattctttca cgtagcaact catggtggat ctgactcatt ttgttcaatc cctgacttga
    21181 gtaagaaagg atcatttcag gtgtttgaaa agactggcct gcattcaatt cccacgaaaa
    21241 acgatggctg ttgatcccac cgacgactct caattgattg atctgatctt tttcaagttc
    21301 gaaagaatgg ttgccggaat aaacaaattg aagtccgatc gcttctccag tattttctgt
    21361 cgtatgatga tgaactaaag caataaagtt attcatatgg tgactgctcg ttcctcgacg
    21421 gctttcaaat acttttgttc cagataaaac agattgccgt gaaatctgtc tttcattgac
    21481 atgtgctcct ggcaaagcaa tgacttcatc aaatcgccta gtatgggcaa agtctagctg
    21541 gaaactagcc gctttttcta gtttgattgt ttctccggtt tcatttctta tctttacaga
    21601 tcgtgtgatc actgctctat cagtaaatat ggtatagaac aaatcgaaat aaatcgctgt
    21661 ttctctatcc ttaagtgaaa tcaccaacgt ttgtgcctct gacttgtcca tcacataagt
    21721 ttgaggcaag ccttcgatct ctggcttccc atctgtaata taatggctgt catatctcag
    21781 atccagtaag tctgatccat tcttgcgctg aatgatcgat gcgggcgttc gaaagtccat
    21841 gctgccatga gaagagtatt cttgcggtag tgtatctttc gacagagacc ggtcaggatt
    21901 taagggaaca tttcctgaaa atccacgatc tcttcgggga taatttttat tgtctttgta
    21961 ctgcttgact ggtttgccaa aataaatatg cgccaataca ttgctttctt ctatctttat
    22021 cagataagaa agaaatgtat ttcgtaaatg gaagactcgg ctcttttcat caaataagat
    22081 gaaattttta tctgtttttc tatgcgtaat atccatcatt tcactcccaa caaaacggaa
    22141 accgtttact tttttttata attcctgtat actgtttact aaacaatttt gtcaataaaa
    22201 attttttatt tttttgagga gtgtgtaaaa atggttggaa ttagagatgt cgcacgaaag
    22261 gcaaatgtct ctcctgctac agtttcccgt gtgttgaata acgatcagac gatccatgtg
    22321 gctcagacta ctcggcaacg gatagtagag gcagctgctg cgttggatta tgacatcagt
    22381 actcgtaaat atatcaaaaa gagaatgcct tcgattggtg tgatctctac gatcggcaaa
    22441 gcgagcgaag aacaggatat ctattacaaa catttgcgag tagggatgga agaagaagct
    22501 cgacgtctgc atttagggat gaatcgaatc tataatctat ctgataatcc taaacaatgg
    22561 gaagatctag atcagttagg tgcggtgatc gttgttggga ctgttacgaa agaatcgatt
    22621 accgccttgt taaaacaaaa catgcaaata gtcgtcgtgg ataaccctga catccagcaa
    22681 gaggtcgata tggtgtatgc agatcttgaa cggatgacta aaaccgtact ggaattgttc
    22741 ttagaaaatg gtcataaaag aatagcctat atcgggggat ataaagtcga tatggatgaa
    22801 ttcggtggga agcagatttc tataaatgaa aagaggatgc gtgcctatca gcattttatg
    22861 atcgatcatc acttagaaaa atatatgtct tatcatctag gtggctggac agaaaaacaa
    22921 ggtgaggtac ttgcgactaa tctattagaa aatgaatccc ctcttcctac tgccattctt
    22981 gtcgggagcg atccaatggc aattggtgtc tatcgggcat tgaaacaaaa aaatatccaa
    23041 attggagaag agattgttgt agcaagcttt gataatatcg agacaatcgc aaacctctcc
    23101 cctggcttga ccagtgttca aatcaatgcg aaatcaattg ggcaagcagc tgttcgaatg
    23161 gcattggagc gaattgacgg tatacgggac gaaccaatca ttttgactta tcctgcacga
    23221 ttgattgtta gggaaagttt tatcccaaga acaaaaaggt attgaaagag aggttgtgaa
    23281 aagccgcttc gtttcttcat actcaaaacg aaacggcttt ttcacaacct cttacttata
    23341 cttattcaca aaatccaatg tctgctggta acaattttgc gattctttta gcgtgtaatc
    23401 aaattggtat tcatgggtaa tctctttttt tgtatctgta taaaacaagg attgcacggg
    23461 tacctttaat tctgtcaacc gattttctaa tgcttgacct tgctcctgga atgagtatgc
    23521 atttccgtca gttatatacg ttggcggaaa ttccttagaa acatggtcag ccacactagc
    23581 ttctttcaat tgctcactcg ttttccaatc ttttgttcca atcaacgacc acgcaacggt
    23641 tttgacgaaa aacttcataa atcgatcatc cgaatgctgc tgtgctgtta gcttcaaatc
    23701 aacaggtccg caataagaaa tggttccttt cagactatct tttggaagta gctgtttgat
    23761 tttcatttgt ttagcatacg catcattcgt ttgtatagct gcatattgca atgcgatttg
    23821 tgaacctgca ctatctccac caaaaaataa ttgttccatg tctagcaatt tgtcgtcttt
    23881 ttcttcagct aataaatctt tgatcagttc attcacttga agaacttgat tagggtattc
    23941 tgaatcaggc gctaattcat aattcatcgc aaccactgcg atgttggcgt ctgaaactaa
    24001 ttttgtcgca aattctttga cacccgattt atctccgccg acgaatcctc caccatgtac
    24061 ccaaaataga acaggaacag gccccttgct gttttttgga tagtagatgt cataagtatt
    24121 ctctttatac ttggactcat acgtcaaatc tgtttttttc gccacgtttt tttctgcttg
    24181 atcgaacgtt tttttatcag tgatttgaac agtatttgaa aacatatggt tgatcaagaa
    24241 tgctccaggt ctgggggaaa gctggaaggc aagaaagatt gcaaacgcga tcccaagaat
    24301 gattccgaag aaccatccga taaatttaag aattttcttt ttcataaggc tccctcagta
    24361 gttagtatta agcattctga ttataccata gtgttatttc ctatcaagct ctcctagatg
    24421 atttaatgat tttccccaaa cttcttctgc aatgcttttg acaaaagaaa ttttttccat
    24481 tgttcttcaa acaaaacatt ttcttcttct gttgaagcaa atccacattg aggacttaag
    24541 cacaaacgat ccaaaggcag atatcgtgtc gcttcgtaga tccggtcaat cacttgctgg
    24601 tgctcttcca tttcgccatt tttcgttaca gtcaaaatct aagacaacta atttatcttc
    24661 agagactttc tctaaaagaa caaaactccc agcacgttca ctatcgtatt ctaaataata
    24721 ggcacggaca ttttcttgag taaaataatg ggtctgctac gtcgtcatcc cccctgatgc
    24781 cgccaaaatc gaataataat ttccgcgtca aacatgtata tttagtgttg aatcatttga
    24841 gaatatgaaa ataaaaatct ttttgatcaa tcagttaatc aaattgaaat aacgaaaaat
    24901 ctgagacaga atgacgttca ttctgaccca gatttgattt tgcacaactc aacagtcctt
    24961 attggcaaat cgccaaaata atgtagacta actaaaaaga ctaagaaaca ataacaaaag
    25021 ttaacacttc ttagtctttc tttagcacgt ctatttatta aagattttag ggccttttct
    25081 catgttttta cgatcattct taggtgtttc catttgtttg gatcggcctc caccttgttt
    25141 ctttttgatc aattctttca ttttttcttt ttggtccatt tttattctcc tttaacgaat
    25201 gaagcgacta attcgatatg atgggtttgc gggaaaagat ctacaggctg aactttcttc
    25261 acggcataac ctgcttctgc aaataactta gcatctcttg caaaagttgc cggattacat
    25321 gagatataga cgattcgttc tggtgacatt tcgattgctg attcaataaa atgatgatct
    25381 aatccttttc gtggagggtc aactacgatc acagatggtt tgatcccttt ttcttgccat
    25441 tttttcataa ctttttctgc ttttccgact tcataatgaa cattttcgat tttattattt
    25501 aaagcattga actgtgcatc ttcaattgct tctggaataa cttccatccc atacacctta
    25561 tccactctgt ctgctaaaga caagccaatc gtacctattc ctgaataagc gtcgatcaca
    25621 atgtcttttt tatctaactc ggcaaactcg atggctgttt ggtacagata ctctgcttgt
    25681 tgagtattta cttgataaaa tgactttgct gagattcgat aggtttttcc taatagctga
    25741 tcttcgatat agtctctgcc atataaaact ttttctttgt ctcctaaaat cacatttgtt
    25801 ttttcttcat tgatattttg gatgaccgaa accacttctg gcaattcttc atgaatagct
    25861 tcagcaattt ccttggattt aaagaatttt tctttacgag taactaaaac gaccatcatt
    25921 tcatgggaat aatgaccacg acggataatg atgtgacgaa gctgtccttc atttttttct
    25981 tcattatatc ctcgtacttg gaaccgttgc aagatatctc tgactacttt gattgcttga
    26041 tcgatgacag gatcttggat ataaaaatct tcgataggga ctagatcatg gctattcttt
    26101 ttgtaaaaac cggtggctaa ctgtccatcg atacggcgaa cagggatctg tgctttatta
    26161 cggtagccga atggttctgc cattccgacc gttggaagta caggaacttc tggcatctta
    26221 gcaatcttcg ccattacatg ctctacttgt ttttgtttga agacaagctg ttgttcatac
    26281 ttcaaatggg ctaaaggtgc gatacctatg cgaagtaatg cattgttttc tacaggctga
    26341 cgatcaggtg attgtgtaat aaatgtttcg acttttccat atccaaactt attgcctgct
    26401 tttactacta gtatttctac ttcttctcca gggagtgcat tttcgataaa taatggataa
    26461 ccatcgattt ttgctacccc cattccttca taactcaagt cgacgatttc gactgtatat
    26521 cgttcgtttt tctttactat ttgctgttct gtcatatttt gctcctttaa gcctattttt
    26581 caatcctact gaactctact ataaatcagc taattacaca actaaaaccg gcactgacct
    26641 tactacgttc agcaccggct tttgattaat tcttttgatt aggtgtttcg tctgctattt
    26701 ttccgtcacc gtcgatatct tcatccgtta aacgttcgac ttcttttacg aattctttgc
    26761 tgacaacctc taattcttct tcatctgtac ctgtgattgc ttcatcagga atctgatcgg
    26821 tattggcaaa gaactcaatg tgttgatgaa gattttggaa atgcatcggt gcttccccgc
    26881 cgtattcacc atctaagttg atcattactg gtcgattgat atcatcttct gtttcaacga
    26941 acaaactgct tgttttggta tagattattc ttggatcatc gacatgtcga ccgccattca
    27001 gcatgagtgc tgcaatatgc aagatctcaa agatatttgc tgtcttcaca atgattaaag
    27061 aaaacttccc atcatccaat ttggcatctg gcgcgatctg ttcgaatcct ccaacagagt
    27121 tcgtcagccc taggaaaaac atcgaagcat ttccgatata ttccccttca tcatacttca
    27181 agcgcatttt gattggcttt actcgaggga gcatctctgc tcctttcgca agataagcaa
    27241 gataaccaaa aatactcttt agttctgatg gaacttcata agtcaattct gtcaaatagc
    27301 cacctgcagc gatattgatg aagtaactgt tatcagaaag gccgatgtcc atttttacgg
    27361 tttggtgttt ttttatcact tctgctgctg ctttaatatt atctctagga atttttaatg
    27421 ctcgagcata gtcgttcgtt gtaccagctg ggatgatggc cattttagga cggtgttcaa
    27481 gcggagcgat tccattaacc acttcgttga ttgtgccatc gccaccagct gccactacta
    27541 gatcaaaacc tagttctgcg actctacatg cttcattctt ggctgaatct ggttctggtg
    27601 tagttgcata ggcgctggct tcaaatcctg cttcttctaa tgcctgtagg atatccgcca
    27661 aatttttttt caataattct tttcccgagg tggggttata aattacgcgt gcttttttca
    27721 ttttcagcct ctatcgtttc gctaattcat ctttaagtag cttattcacg acaccaggat
    27781 ttgcttgtcc tttagttgct ttcatgattt gaccgactag gaagccaacc gcacgatctt
    27841 ttccattttt gaaatcatcg acagattgtt ggttgttatc caaaatttca ttaatgattg
    27901 gcagtagttt gttcggatca gataattgca cccaaccatt tttttcaact acttcttggg
    27961 cttctccgcc atttgtgatc aattcacgga agactttttt ggcgattttt gagctgatcg
    28021 ttccatcggc gatcaaacga atcattcctg ctaagttctc aggtgtcaat tttgtctcag
    28081 ctaattccag tttctcactg ttcaagtaag cagaaacttc acccatcaac cagttagatg
    28141 cttgcttggc atctgcacca ttttccaaaa cagcttcaaa aaaatcagac atttcttttg
    28201 taagtgtcaa taccattgcg tcatactctg gaagtccaaa ctcacggata tagcgttcgc
    28261 gacgagaagc tggcatctca ggcaaactag cttttacttt ttgaatccat tcgtcatcga
    28321 tcacgaattt cgggatatca ggctctggga agtaacgata atcactagac ccttctttga
    28381 cacgcatcaa aactgtttta ttcgttgttt cgtcaaaacg gcgtgtttct tgttggattt
    28441 ctcctcctga aagaagaact tttgcttgac gtttttcttc aaaagctaaa ccttttttca
    28501 cgaaagataa agagttcaag tttttcaatt ctgctttcgt accgaactct tcttgtccat
    28561 aagggcgaag agaaatattg gcatcacagc gcatagagcc ttcttccatt ttcacatcgc
    28621 tgacttctgt aaattggata attgatcgca atgcttctag ataagcgtat gcttcttctg
    28681 gtgaacgcat atcagcttca gaaacgattt cgatcaaagg cgtgccttgt cggttcaaat
    28741 caacgtaaga ataaccgcca ataccatgca tgttttttcc agcatcttct tctaaatgga
    28801 cacgttcgat ccggattttt ttctttttac cttctacttc gatttcgatc catccgtcat
    28861 gaccgattgg ttgatcaaat tgggaaattt gatatgcttt tggattatct gggtaaaagt
    28921 aatttttccg gtcaaaatga gtatctttag agatttcaca gtttaatgcc aaagctgctt
    28981 tcatcccgaa ttccagcgca gctttattca ttactggcag cacgcctgga taaccccagt
    29041 cgatcacgtt tgtattgctg tttggttctg caccaaaatg agctggcgct ggagagaaaa
    29101 tttttgagtt ggtttttaac tcgacgtgga cttctagtcc aatgactgtt tcaaaattca
    29161 ttcgtctttc cctcctaaaa tagctggttg ttgtttatgg aattctgttg cttgttcaaa
    29221 cgcatatgcc gcttgataca tcgttttttc atcaaaataa ttaccgatga tctgcaatcc
    29281 aactggtaat ccttctgata aacctgccgg tacagacata cctggaagtc cagccaagtt
    29341 gacagggatc gttaagatgt cactcatgta cattgtgatt ggatcgttaa tgttctcacc
    29401 gattccgaat gcaactgttg gtgaagatgg cccgatgatc aagtcataat ctgcaaagac
    29461 tttttcaaaa tctcgtttga tcaatgtacg gacttgtcct gcttttttga agtaagcgtc
    29521 ataataaccc gcgcttaagg agaatgtacc taacatgata cggcgtttta cttcttcacc
    29581 gaatccttct gaacgtgagt tgacatatac atcatctaat gatttcacat tttcagagcg
    29641 ataaccgtag cggataccat cgaatcgttg caaattggaa cttgcttctg atgaggcaat
    29701 gatataataa acagccacac cgtattttga atgaggcaag ctgacttctt ccacaacagc
    29761 acctaatgaa cggaatgttt ctgctgcttt caatacagct tcttttacgc caggggccac
    29821 accttcgcct aagtattctt taggtaaagc aatcttcatt cctttgatgt cgcctgtcag
    29881 tccctctgca aaatcaggaa ctgaaacgcc tgaagaagta ccgtcttttt cgtcataacc
    29941 gctgatagct gtcaatgcta atgcattatc tttcaccgta cgggtcattg gtccgatttg
    30001 gtcaagagat gaagcaaagg caatcaaacc aaaacgtgag acacggccat aagtaggttt
    30061 catccctacg atgccgttaa aagctgctgg ttggcggata cttcccccag tatcactacc
    30121 taaagaaact ggaatttgtc cagctgcaac tgctgctgca gaaccaccag aagagccacc
    30181 aggtactttt gttgggtccc aagcattttt tgttttcttg aaataagaag tttctgtact
    30241 tccacccata gcaaattcat ccatgtttag cttaccaaca gggatcatat ctgcttgata
    30301 gattttatcc atgaccgttg catcataaat tggttcaaaa ttgtaaagga tcttagatgc
    30361 agcggttgtc aagatatctt ttgttacgat attatccttg ataccaattg gaataccagc
    30421 aaggacgttg ctttcatcaa tccctttttc atctaaagct tttgcctgtt ccaatgcttt
    30481 ttcttcgttc aatgtaatga atgcctcgac ctcaggctct gtttctttga ttcgttcaaa
    30541 tgttgttttt gtcaaatctt gtacagtgat ttctttcgat acaagcatat gatgcagttc
    30601 ttctagagaa cgattgtgta attctgtcat tatgcgccag cctccccatt atcgatgatt
    30661 gcgggtactt tgataaagcc gtcttctgtt tccggcacat ttttcaataa ttcatcgcgg
    30721 ttccatccag cttgcgcccg atcttgtcgc atcacgttta ctgtttcaac cacattcgac
    30781 gtaaatggaa caccttccgt atctacttct tccagcattt caaccatatc gatgatttta
    30841 cctaattggt cggtaaaact tgcaagttct tcatctgcga acgcaagttt tgctaatttg
    30901 gcaacgtgtt tcacttgttc ttcactaatc gccatactac cccttctttc taaacgagtt
    30961 aaaaactttg ctctctattt taacacaaga gtgccgtgtc tgaaattgtt tattgaaatt
    31021 tgtctgaaaa aactcatttt tcattcttct actgagcgac ttttagccaa tgcatctgcc
    31081 atttgatctt ctgtccaaac ttcgattcct aattcttgtg ctttggtcag cttgctgcca
    31141 gcatcttctc ctgctaccac gatatccgtt tttttcgata cgctaccagt cactttcccg
    31201 ccaagatttt cgatcgtctc ttttgcttct tcacgagtaa atcgtgttag tttaccagta
    31261 aggactactg ttttttcttt aaaaggagac tcgacttctt gcaattgggc atttcgaagc
    31321 cctttgtatt cgaaattgac gcctgcttgt tttaattcat tcatcaattc atggacttct
    31381 tcgttactga aataagtgac tacactgtcg gcaatgatat caccgatcgt atcaagcgca
    31441 ataatcgact catagtcact tttactcaat gtttctagat caccgaaatg ttctgctaaa
    31501 atttttgctg ctttcgctcc gacatgtcgg attcctaacc cgaaaatcaa ccgctcgacc
    31561 gaattatctt tgctgttgtc gattgctgtc aaaatattat ttgctgattt ttcttttatt
    31621 ttgtccaacg tcaataactc ttcttctgtc aatttgtaaa gatcagcaac atctgctact
    31681 agttttttat catacatctg ttctagtacg cgcggcccca acccatcgat attcatcgca
    31741 tttcttgaaa caaagtggtt caaaccttct ttcatttgag cagggcattt aggattgatg
    31801 caccgtaagg ctacttcttc atccaaatgg acaagttcac ttccacaaac tggacaatgt
    31861 gtaggcaatt ggtattcttc gctgtcttta ggtcgtttat ctaacacgac ttgcgaaact
    31921 tctgggatga tgtctcccgc tttataaatc agaactgtat ctttcaagcg gatatccttc
    31981 aacttaatat aatcaccgtt atgcaggctg gcacggctta ctgtcgttcc tgctactcgg
    32041 actggtgtca tgatagctgt tggcgttact acccctgttc gaccgactgt ccattcgatg
    32101 ttttcgatta gcgtttcaac ttcttctggc ggaaacttgt aagctgctgc ccatctcggt
    32161 gctttgatag taaaaccaag ttgatcttgt agcgagaatt cattcacttt gatgacgatt
    32221 ccatcgattt catagggcaa atccacacgt ttgtcatgat attcttcaat gtatgaccac
    32281 acttcatcaa tcgaatgaca tagacgtttt tcccgattcg tgtggaatcc aattttttct
    32341 agctcttcta gcgcatcata ctgggttttt gcttgcatag gaccgaaatc agctactgtg
    32401 tataaaaaag tgtccagatt tcttttcgct gtgattttag aatctaactg acgcaaagaa
    32461 ccagctgcgg cgttccgagg attcgcaaag atatcttttc cctctgcttc tctgtcttgg
    32521 ttcaattgga caaatgaccg ttttggcatg aaacattcgc ctcttacttc gatgttcatt
    32581 ggttctttta atttgattgg gaccgaccgg acagttttta ggttttcagt gatgttttct
    32641 cctacagttc catccccgcg agtcgcacct ctcacgaaat ttccatcttc ataacgcaaa
    32701 gaaacggaaa gtccatctat ttttagttca cagcaatagt caactacacg tcccactgct
    32761 ttttgtacac gttgatcaaa agctatcagc tcttctttgc tgaaaacgtc gttcaaactg
    32821 taaagcggaa tatcatgagt gactttttca aaaccttcta atacttttcc gcctactcgt
    32881 tgagtgggag aatcagacgt gatcaaatca ggatattgtt cctcgattgc tactaattct
    32941 gcgtattctt tatcataaac atagtcttcc actgttggtt tatcttctac gtagtattcg
    33001 cgagaccatt ggttcagtct tgtacgaagt tcttctgctc gtttagcagc ttcgtcaatc
    33061 gtcatttcat gttccatcat ttaccctcca ctactaagct ttttcaattg gcgcaaaggc
    33121 agccaaaaga cgttttactc cttgacttgg gaaagccaca tctagttcta gatccttcga
    33181 cgtcccgctt actcggacga ctgttcctag accccatttt ttgtgtttga ctttatctcc
    33241 aggtttccag ctgttatttt cccctccagt agcactttta gagggaacaa ccgctgtctc
    33301 tggctgttta tagctatatg ctgttttttt agcgaataca ggcgtttttt taggcgtagg
    33361 acgcatgcct tcgatttcca gtaactcctg atcgatttct tctacaaaac gagaaggtcg
    33421 gttatattgc gtccgtccat ataatgttct ggagaaagca tttgttaaat acaacgcttc
    33481 ttctgctcgc gtgatcccca catatgcgag acggcgttct tcctccagtt cgctttcttc
    33541 catcaatgct cgagataaag gaaaaacccc ctcttctaga ccaatcagga atacaactgg
    33601 aaattctaat cctttggctg catgcaaagt catcaatgtc acttgggaag catcttcttc
    33661 taaattgtca atgtcggaaa caagtgccag atcatttaag aagaccgtta gtttttcttc
    33721 tggtgcatca gcgtcttctt cattttgctg ttcgaattgt ttgtcgaatt cttgtgtgac
    33781 cgttaaaaat tcctccaagt tttcgatgcg tgcttgtgct tctaatgtat tttggatttt
    33841 taagtcttct agatatccgc tacgatccaa aacctctttc gtcaattctg tcactgtcaa
    33901 gtatgggatc atctgagtga cttcttggat catctctcca aatgcaccta attgctgtcc
    33961 tgcttttcca ccgatatttg ccagatccac attttgcgct gcttcaagca gtggccattc
    34021 atgaagagaa gcaaaactgc gtagtttttc gatagatcct ggtccgatgc ctcgtttggg
    34081 cgaattaacg atacgctcaa aactgattga atcttgagga tttaccagca cattcaaata
    34141 cgctaaaata tctttgattt ctttacgatc gtagaacttg tgccctccaa ccattttata
    34201 aggaatattt gctttcaaca gagtttcttc cattacacga gattgtgcgt tcgtccggta
    34261 caagatggca aagtcgccgt aattccgatg attgcttcga atctcttctt gcatccggtc
    34321 tacgataaaa cgggtttcgt ctcgttcatt atctgcacgg tagtaagtga tcttgtttcc
    34381 ttctttgttt tctgtccaca agttttttgg ttttcgattg ctattgtttt caatgacttg
    34441 gtttgctgcg ctaaggatgt ttttcgtgga gcgatagttt tgttctagca aaattactgc
    34501 agcatctgga taatcttttt caaaatccaa gatgttctgc atatctgcac cgcgccagcc
    34561 gtaaatactt tgatctgcat ctcccacgac gcacaggttc ctaaatctac ctgccaataa
    34621 attgactagc gtatactgtg cgtgatttgt atcttggtac tcatctacat gaatataatg
    34681 gaatttgttt tgataatacg tgagtgaatc aggatgttct tcaaataatc gaatcgtatt
    34741 catgatcagg tcgtcaaagt ccatacattg attatattga agctcttttt ggtaagcagc
    34801 ataacatttt gccgcaatct cttcgtaata actgccttgc atttttgcaa aatcctgagg
    34861 ggtctgcagg ctgttttttg cttgagagat tgttcctaat atacttcgag gatcatattt
    34921 tttcggatca atgttcagtt cttttagtat ccgtttcatc aaggtcagct gttcagaaga
    34981 atcgatgatt gtaaagttcc ggttataccc gataaaatca acatctcttc ttaaaatacg
    35041 cacacacatc gagtgaaaag tcgataccca gacatcttcg cctccagatg cgagaatcgc
    35101 attgacacgt tctttcattt cttttgcagc cttattggta aaagtaatcg ctaggatgtt
    35161 ccaaggattg acttcttttt cctcaatcaa ataggcaatg cggtgtgtca gcactctcgt
    35221 ctttccactt cctgcacctg ccattagcag taatggtccg tcagtgtgaa gaacagcttc
    35281 tttctgacgg gggttcatcc cgtttaataa ttcagctttg gatgacatta acaacatcct
    35341 ttcttttatc aatcttgtta attatagcat tttcttggct ttcattaaac tagctagttc
    35401 aaaatcattt gtttcttttt atggattttt ccttgtcaat tcgttgattt cgcgctaaat
    35461 taaaagaaag cgaggcgttt gaatggaaaa aaaaggaaaa atcaagaaat tagataagac
    35521 tcagatatat tttattctaa aaggaatatt tgttggactg ctgacaggaa tcgtcgttag
    35581 cctgtttcga ttatctatcg aaaagctaag cgatttagtt cgaagtatct atgaaatgag
    35641 tcgggaacag ccgatttact taattggcct agctatttgc tgcatccttg cagcattttt
    35701 cgtgggttat ctggtcaaaa atgaaccgga tatcaaggga agcgggattc cacaagtagt
    35761 gggacagctt cgcggggaat tatcaatgaa ctggttctct gttttatgga aaaagttcat
    35821 tggcggtgta ctttcagttg gtgcgggcct ttttctaggt agagaaggac cttctataca
    35881 gcttggcgca tccattggac aaggagctgg acaattgttt cggagtccat cttcagaaga
    35941 aaagatttta atttctagcg gtgcaagtag cggacttgca gcagcattca atgctcctat
    36001 cgcaggatta ctctttgttt tagaagaaat ccatcactcc ttttctccac ttgtttggct
    36061 gacatcattt gcttcagcaa tcactgctaa cttcgtctct ctttactttt tcggcttgag
    36121 acctgtttta tatctaggtg accttccttc tttgccgttg aaatattatg gttccttagt
    36181 gatcttagga gtacttctag gcatcttagg ttttatttat cagaatgtct tgctggcttt
    36241 gccaaaattt tacaaccgat tgcctttacc agcttatttt cacgggttcg ttcctttctt
    36301 gctgattttg ccaattggtt atttatggcc tagtactcta ggcggaggca atcaaatcgt
    36361 tttagctttt ggacatgctt ccttgccaat cattatgatt atcggtttgt ttgttcttcg
    36421 attcgttttt tccatgattt cttacggtgg gggtcttcca ggggggattt tccttccgat
    36481 attgacattg ggggctttaa tcggtagctt ttatggaaac attatggttg atttcgggat
    36541 ggatccaatc tacatcaagg attttgtcgt tattgccatg gctggttatt tcacagcgat
    36601 tggaaaagca ccgctgacag caattatttt agtgacagaa atggttggct ctcttaatca
    36661 tctgatgcct ttaggattgg ctgctcttgt tgcttatatc gtcaatgacc ttctcggcgg
    36721 taatccaatt tacgaatcat tattggaacg tctacttgga aatactcaga ccgcctcact
    36781 aaaaggtgca aggacaactt ttgattttcc agtaacggca gagagttctt tagacggatt
    36841 aatggtacga gacttcaatt ggcctaaaaa tatgctgcta atctctatac gcagaggaaa
    36901 tcaggaaatc ttgactcacg gtgatacgat catgaatgta ggagatattt tggttatctt
    36961 gactgatgaa gcaaacttgc caagaatcaa gcaggaaatc gaggctaaat cttctatcac
    37021 aaatttgaag caatcatttt aacgaacatg gaaaaactat tttacaacaa ctattcatct
    37081 acactacttg attctatatg attctataaa aaaagaagag gctgggaaaa cccagcctct
    37141 tctttttt
//
LOCUS       DAZKCH010000018        36998 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000018 DAZKCH010000000
VERSION     DAZKCH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.018"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..286
                     /locus_tag="ACG84X_000937"
     CDS             <1..286
                     /locus_tag="ACG84X_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126834.1"
                     /translation="KSFLKVISKKRNLIKTTQLLKKYPGLLHTSIQFPQLITMIHRFI
                     RMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVAMEKAN"
     gene            345..785
                     /locus_tag="ACG84X_000938"
     CDS             345..785
                     /locus_tag="ACG84X_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126835.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            797..1465
                     /locus_tag="ACG84X_000939"
     CDS             797..1465
                     /locus_tag="ACG84X_000939"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFP9126836.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1529..2152
                     /locus_tag="ACG84X_000940"
     CDS             1529..2152
                     /locus_tag="ACG84X_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFP9126837.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2208..2594
                     /locus_tag="ACG84X_000941"
     CDS             2208..2594
                     /locus_tag="ACG84X_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFP9126838.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            2807..4198
                     /locus_tag="ACG84X_000942"
     CDS             2807..4198
                     /locus_tag="ACG84X_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFP9126839.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVATQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            4809..5177
                     /locus_tag="ACG84X_000943"
     CDS             4809..5177
                     /locus_tag="ACG84X_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFP9126840.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5357..6298
                     /locus_tag="ACG84X_000944"
     CDS             5357..6298
                     /locus_tag="ACG84X_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFP9126841.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6367..7098
                     /locus_tag="ACG84X_000945"
     CDS             6367..7098
                     /locus_tag="ACG84X_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9126842.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7242..9422
                     /locus_tag="ACG84X_000946"
     CDS             7242..9422
                     /locus_tag="ACG84X_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFP9126843.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9442..9924
                     /locus_tag="ACG84X_000947"
     CDS             9442..9924
                     /locus_tag="ACG84X_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFP9126844.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            9940..10701
                     /locus_tag="ACG84X_000948"
     CDS             9940..10701
                     /locus_tag="ACG84X_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFP9126845.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            10832..12166
                     /gene="murC"
                     /locus_tag="ACG84X_000949"
     CDS             10832..12166
                     /gene="murC"
                     /locus_tag="ACG84X_000949"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFP9126846.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12473..12958
                     /locus_tag="ACG84X_000950"
     CDS             12473..12958
                     /locus_tag="ACG84X_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFP9126847.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            12951..13634
                     /locus_tag="ACG84X_000951"
     CDS             12951..13634
                     /locus_tag="ACG84X_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFP9126848.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            13760..16405
                     /gene="polA"
                     /locus_tag="ACG84X_000952"
     CDS             13760..16405
                     /gene="polA"
                     /locus_tag="ACG84X_000952"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFP9126849.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16450..17286
                     /gene="mutM"
                     /locus_tag="ACG84X_000953"
     CDS             16450..17286
                     /gene="mutM"
                     /locus_tag="ACG84X_000953"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFP9126850.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17250..17879
                     /gene="coaE"
                     /locus_tag="ACG84X_000954"
     CDS             17250..17879
                     /gene="coaE"
                     /locus_tag="ACG84X_000954"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFP9126851.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            17931..18263
                     /locus_tag="ACG84X_000955"
     CDS             17931..18263
                     /locus_tag="ACG84X_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFP9126852.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18575..19066
                     /gene="nrdR"
                     /locus_tag="ACG84X_000956"
     CDS             18575..19066
                     /gene="nrdR"
                     /locus_tag="ACG84X_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFP9126853.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19089..20462
                     /locus_tag="ACG84X_000957"
     CDS             19089..20462
                     /locus_tag="ACG84X_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFP9126854.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20462..21388
                     /gene="dnaI"
                     /locus_tag="ACG84X_000958"
     CDS             20462..21388
                     /gene="dnaI"
                     /locus_tag="ACG84X_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFP9126855.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21517..21957
                     /locus_tag="ACG84X_000959"
     CDS             21517..21957
                     /locus_tag="ACG84X_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFP9126856.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22101..22802
                     /locus_tag="ACG84X_000960"
     CDS             22101..22802
                     /locus_tag="ACG84X_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFP9126857.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            22799..23920
                     /locus_tag="ACG84X_000961"
     CDS             22799..23920
                     /locus_tag="ACG84X_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFP9126858.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            23935..25167
                     /gene="pepT"
                     /locus_tag="ACG84X_000962"
     CDS             23935..25167
                     /gene="pepT"
                     /locus_tag="ACG84X_000962"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFP9126859.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25299..26207
                     /locus_tag="ACG84X_000963"
     CDS             25299..26207
                     /locus_tag="ACG84X_000963"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFP9126860.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26242..26514
                     /locus_tag="ACG84X_000964"
     CDS             26242..26514
                     /locus_tag="ACG84X_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFP9126861.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26525..27571
                     /locus_tag="ACG84X_000965"
     CDS             26525..27571
                     /locus_tag="ACG84X_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFP9126862.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            27822..30431
                     /gene="clpB"
                     /locus_tag="ACG84X_000966"
     CDS             27822..30431
                     /gene="clpB"
                     /locus_tag="ACG84X_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFP9126863.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30582..31268)
                     /locus_tag="ACG84X_000967"
     CDS             complement(30582..31268)
                     /locus_tag="ACG84X_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126864.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31246..31740)
                     /locus_tag="ACG84X_000968"
     CDS             complement(31246..31740)
                     /locus_tag="ACG84X_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFP9126865.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(31760..32980)
                     /locus_tag="ACG84X_000969"
     CDS             complement(31760..32980)
                     /locus_tag="ACG84X_000969"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9126866.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33127..34962
                     /gene="lepA"
                     /locus_tag="ACG84X_000970"
     CDS             33127..34962
                     /gene="lepA"
                     /locus_tag="ACG84X_000970"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFP9126867.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            35158..36069
                     /locus_tag="ACG84X_000971"
     CDS             35158..36069
                     /locus_tag="ACG84X_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126868.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
BASE COUNT        12482 a         6400 c         7919 g        10197 t
ORIGIN      
        1 aaaaagcttt ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt
       61 gaaaaaatat ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat
      121 ccatcgtttt atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga
      181 cacatttcga gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag
      241 aaatcggaat gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt
      301 ggattttttt gtcataataa atattagatg atggaggaga taatatgatg caaacatggt
      361 tagaaaggct aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga
      421 aatttgatca gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc
      481 gttggttgcc ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat
      541 ttcgtttcct atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat
      601 atcttgatag agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg
      661 atcgaaaaag ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta
      721 aaggaaaagg acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg
      781 tttaagggag aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt
      841 tgaaaattac tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc
      901 agcagttgcc ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc
      961 tgttttgaaa cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg
     1021 gcttcctata ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa
     1081 aaacaaagat aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg
     1141 atatacggaa gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt
     1201 ggatccgcat ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc
     1261 cttatggcaa gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg
     1321 tcatggtaat agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat
     1381 ggatacgatc gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac
     1441 aattctggac aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa
     1501 agaagcaaag gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac
     1561 attgtttgat acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg
     1621 tatcagtatg gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt
     1681 gatcaatgaa tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa
     1741 agaaagtacg gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa
     1801 agacaacggc ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct
     1861 gttaaaagaa catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt
     1921 tcctcgtaaa cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag
     1981 aacagacacg atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg
     2041 agtcgctact tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt
     2101 ggtaggaaat ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct
     2161 ttcaaaggag atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa
     2221 gacaaaaaga agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag
     2281 aaacagattt gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag
     2341 aacatagcat cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat
     2401 ctggaagtgt gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg
     2461 tcacacaaga agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt
     2521 cttatgaggt gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag
     2581 aaaaacaaga atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt
     2641 ttttttatta ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat
     2701 aaaagtcact gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt
     2761 tacttccttc gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat
     2821 cacagtttta gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa
     2881 gcgccataca aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg
     2941 cggtctgctt caattgatct ttggtgtaga cgacaaagtc gctactcaat caatggaatg
     3001 gatcgggatt gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt
     3061 gtttatttcg atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat
     3121 tagtgcgact gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat
     3181 tggttcaaca atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac
     3241 agcacgaatc tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca
     3301 gcagatttta tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac
     3361 aagtacgatt ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa
     3421 aagaaaagcg ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat
     3481 cattatgcgg atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat
     3541 gacaaacgtt ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt
     3601 tgcttcttac gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc
     3661 aaaagtcaat ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac
     3721 ttcacgttca agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg
     3781 agtagatgat gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg
     3841 ctgtgctggc gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa
     3901 tgtctttagt ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg
     3961 tgtagctgga gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa
     4021 cttgccagta gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg
     4081 tacagcagta aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa
     4141 agatttagat cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc
     4201 aaaaagaggt tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat
     4261 agtttctcaa atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg
     4321 tgaataagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa
     4381 tagttcctca tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac
     4441 cgtttaagaa agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa
     4501 aaaatagctt ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa
     4561 caccgtttac cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca
     4621 tataaataca cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt
     4681 atttattatt aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat
     4741 tttcccattt tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga
     4801 ggaaacagat gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa
     4861 atgcaacgtt ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga
     4921 cgcttataat tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag
     4981 catttgttga gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca
     5041 gtaaagatat ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata
     5101 tggtacagct tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg
     5161 cggttacagg taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga
     5221 agtcttttta attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata
     5281 cacaagcaaa taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga
     5341 aggaaggaag aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga
     5401 agaaccagag gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg
     5461 tcgtattcta gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac
     5521 gactgcctat atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat
     5581 cgatccaagc gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt
     5641 aagtttaaag ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc
     5701 gcaagaattt aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga
     5761 ttatgaatat gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg
     5821 agagcttcca gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac
     5881 ctactgtact ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt
     5941 caaagatgtc ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca
     6001 aggagaatta tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa
     6061 ccaagtagat aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata
     6121 tatcaattgt agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga
     6181 aaaacattta ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca
     6241 agaccatgga atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa
     6301 aacaatagtt ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg
     6361 atccacatga aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt
     6421 gaaaaactta ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc
     6481 aatgatcgag gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa
     6541 acaggagcca tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca
     6601 ccggaggact ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg
     6661 attcacccag gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg
     6721 agatattcag aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat
     6781 tatctttttg tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta
     6841 agagacttta tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca
     6901 attgtatttg gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc
     6961 tggattcagg atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat
     7021 ggggttgttt ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga
     7081 ccttggcatg gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct
     7141 ttttattttt atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga
     7201 tagaataaag aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc
     7261 agacgatcat tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta
     7321 ctgtacttaa tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag
     7381 aaatgactgg aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc
     7441 ttgaaaactt agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac
     7501 tgactcccga gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt
     7561 tgtatcgtcc atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac
     7621 ttgaaccact cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag
     7681 aaaaatatat tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc
     7741 atgagattat tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt
     7801 atacgtataa caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag
     7861 gcgtatatga aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa
     7921 tattagctac taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg
     7981 aagcagcaat tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt
     8041 cttcattcgt cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg
     8101 agcgagaact gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg
     8161 gcgaaaacct ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat
     8221 ttgatccggc ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt
     8281 tagcaatcga agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg
     8341 gaccagcttt tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg
     8401 gtacagccag tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata
     8461 aaacctatta cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg
     8521 cacgaaaaga atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc
     8581 gcctgcaaga tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc
     8641 agtaccaaca tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa
     8701 cagcggttaa ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata
     8761 tatcaggatt gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag
     8821 aattcaccgc acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac
     8881 aagcaatcgg attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc
     8941 atcccgaaag ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag
     9001 agcttggtac agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg
     9061 aaagcctatc agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg
     9121 gacgagatat gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg
     9181 aagacttgaa accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg
     9241 catttgttga tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa
     9301 aattcgtcaa gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag
     9361 aacaagtcga tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt
     9421 aacaatgagg agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata
     9481 tcattaaaaa gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt
     9541 acaactggcg ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt
     9601 gaagagtcag acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat
     9661 cttcatctag ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa
     9721 aaaacaggag ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat
     9781 tatcgatgcc aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa
     9841 tatcgttgtg gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt
     9901 aatgaagcac aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg
     9961 aatctaaaag actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt
    10021 gaggaactga cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat
    10081 aaagcagcac aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg
    10141 gggcatgcga ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat
    10201 ggcatgagtg aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat
    10261 aaggcttttc tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg
    10321 gagattcttc attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca
    10381 ctgcaacgca ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc
    10441 gcgaatgctg tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca
    10501 gcaaaagaac tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa
    10561 atggaacgtc tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct
    10621 cacattgata tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa
    10681 acggattttt ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg
    10741 gttgaaattt tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag
    10801 aatggacgct agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt
    10861 tgttggtatc aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct
    10921 aaatgtccaa ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc
    10981 aaatatcacg attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc
    11041 aggaaatgca tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga
    11101 agtgattcgc tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt
    11161 aacaggctct cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt
    11221 ccgtccaaca agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt
    11281 cttttcattt gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc
    11341 aatcatgacc aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt
    11401 tacagctttc caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga
    11461 tgcttattta cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa
    11521 cgatgatatc caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta
    11581 tcatggggat gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt
    11641 aaatgcttta ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc
    11701 agaagaaatg ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga
    11761 catgaccgta gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg
    11821 cgcacgccaa aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac
    11881 gcgtacgatt gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta
    11941 cttatgcgat atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct
    12001 tggagcgaaa atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt
    12061 agattatcat gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca
    12121 agcgtatgaa aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag
    12181 tgtccttata aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg
    12241 caacttatga taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca
    12301 aaaacatgag aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt
    12361 cacgacctct gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg
    12421 ctacttttgg tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat
    12481 aggtaagccg agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc
    12541 cttaacagaa tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc
    12601 aaatcctttg tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt
    12661 tccatcagtg atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc
    12721 aggatcacat gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac
    12781 actgactttt cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc
    12841 tgtagaagcg gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc
    12901 gccacaagtt cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc
    12961 caagtacatc aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta
    13021 tgggacttgc ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat
    13081 tagcaacttt tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga
    13141 ttttagtaat ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat
    13201 ttattgccta ctctcttttg aatggcataa cattagcggt tactcttgca tactacgata
    13261 ttggaacagt aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg
    13321 tcggagtaac aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa
    13381 tcggagtgat cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc
    13441 tgttcatctc cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa
    13501 gcatccgtaa tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca
    13561 tggcattgaa gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg
    13621 gacggaacaa ctaaaaaaga aaaaaattca tcagttgggg ctataccgaa ttatttggta
    13681 tggtcccgct ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt
    13741 acagtaagga gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt
    13801 ggcttttcgc gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg
    13861 tcttcataca aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga
    13921 gcaaccgact catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat
    13981 gtatgcggag tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc
    14041 atatatacgt gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga
    14101 agcagatgat attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt
    14161 cgtgctttca ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat
    14221 cactgtaaaa ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata
    14281 tgatgggttg acgccaaaac agattattga catgaaggga ctagccggag atgcctctga
    14341 caatatcccc ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata
    14401 tggctcagtc gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga
    14461 aaatctgata aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac
    14521 ttcagcgcct gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa
    14581 actcgttccg ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt
    14641 agaagaagaa gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga
    14701 aatgtttact acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga
    14761 ggaaatcgtc ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc
    14821 tgtattcgaa aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt
    14881 atatgatgcg aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat
    14941 cgattttgat gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat
    15001 cgaaggaata gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg
    15061 caaaggggcg aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg
    15121 aaaagtagct gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa
    15181 ccaagaagat cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga
    15241 aataagcggg atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc
    15301 tcgcttaaga gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa
    15361 ttcaccaaag caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa
    15421 aacaaaaact ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc
    15481 aatcgtagag gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga
    15541 gggactgctg aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt
    15601 gacccaaaca ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt
    15661 agatgaaggg agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta
    15721 ttcttctgac tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca
    15781 tttgaaagct gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt
    15841 tggaatcgaa aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa
    15901 ttttggtatc gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg
    15961 aaaagcagca cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata
    16021 tatggaaaga atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg
    16081 ccgtcgatat ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg
    16141 aacagctatc aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat
    16201 cgaattggat aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca
    16261 tgatgaactt gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa
    16321 ggaagttatg gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg
    16381 aaaaacgtgg tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga
    16441 aaagaaaaaa tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta
    16501 gtagtaggaa aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca
    16561 gagacaccca tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga
    16621 gggaagtttt taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa
    16681 ggaaaatatc aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc
    16741 ttttttgagg atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca
    16801 atcgtcgaaa aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct
    16861 ttgccagata gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca
    16921 atcaagccat tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat
    16981 gaagcattat gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa
    17041 gaggtagaac aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga
    17101 ggtaccacga ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca
    17161 ctgcatgtct atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa
    17221 acaaaagtgg cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca
    17281 aagtaggatt tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca
    17341 aagtctttca gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg
    17401 ttgagcctgg aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc
    17461 agcctgatgg gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa
    17521 aacggcaaaa acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa
    17581 tcgcctctct aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag
    17641 gtcattatga ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc
    17701 ttcagcgttt gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta
    17761 gtcaacttcc aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa
    17821 caaaagaaaa acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag
    17881 tatctgtgtc aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat
    17941 taaaaaatca aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca
    18001 ataaagaaaa tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa
    18061 agcagtacca agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc
    18121 ggcaagattt gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc
    18181 cagaaagtga ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata
    18241 caggaatcga agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga
    18301 gaaggtgttc atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag
    18361 ttatttctca gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg
    18421 acacaattac gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac
    18481 agtcgcgttt gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc
    18541 tttatataaa atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa
    18601 taattcacga gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg
    18661 cgaatgtgag aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt
    18721 attagtaatc aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg
    18781 actcatccgt tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa
    18841 ccatgtcgaa aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg
    18901 tgaatatgtg atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag
    18961 tgtttatcgc cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga
    19021 taaagcaaaa gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag
    19081 gcatttcctt ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa
    19141 aagcggctcc gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa
    19201 tcggcggaga agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg
    19261 gcaaaggtcc tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc
    19321 aattttatga tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag
    19381 aagatagtga tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag
    19441 catttttcaa agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat
    19501 tccagaagct tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa
    19561 tcacaaaaaa atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag
    19621 aaaacatcga atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag
    19681 cagattcgac attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa
    19741 gtcttgatga tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg
    19801 aattgacact tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg
    19861 aaaaagaact gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag
    19921 aaacagttgc ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg
    19981 cagcgcttca gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa
    20041 tcaagtcaga aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg
    20101 tttctcaatc aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga
    20161 tcaagaataa tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac
    20221 aaaagaaaat cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag
    20281 caaaacaatc aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac
    20341 gggaaaagct tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga
    20401 aaaaagcaga gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct
    20461 agtggaagac gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa
    20521 gtatgctgaa atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc
    20581 acaccaagaa gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt
    20641 cgtgcaagaa aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga
    20701 gccgaagctg acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt
    20761 gttagcacgg caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa
    20821 agatattcaa tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag
    20881 cttagaagcc ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg
    20941 actgtatcta gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag
    21001 agaattagcg attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga
    21061 gatgaaacag gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc
    21121 acctattttg atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga
    21181 agtattcggt gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc
    21241 gaattttaca atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga
    21301 gccgctaaaa gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat
    21361 gactggtcgc aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta
    21421 gtagtaaaag caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc
    21481 aacaagtaat gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata
    21541 tctgtagttg gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt
    21601 tctgttgatt cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga
    21661 caaagcatat ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg
    21721 cttcagttga aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca
    21781 ttcagcaatg acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat
    21841 gaattgaaaa tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg
    21901 tctatcccac cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca
    21961 ataacatttt ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta
    22021 aggagatatg ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat
    22081 tatctagaag gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg
    22141 gtgactttgt ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac
    22201 ccgttgcatt gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag
    22261 gtccttatga atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg
    22321 tacgccttgc aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga
    22381 ttgcgggtat gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac
    22441 gcttaagcgg acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat
    22501 cttggctgca agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa
    22561 aaatatatga aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg
    22621 agctgatgtt cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga
    22681 caagagagct tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag
    22741 aggcacgtca aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat
    22801 gacaatcagc ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc
    22861 tgaagaagga gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt
    22921 aatgatgaca ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga
    22981 tttgctgatt gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca
    23041 gccacaagaa aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca
    23101 cacgaacatg gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat
    23161 tgaagtggag agttatttag taaagactca tgagattcat tataaaaaac tggccgttta
    23221 tgtacctgtg gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac
    23281 acaaggtgat tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga
    23341 agctggtgca caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa
    23401 agttgaggtt attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc
    23461 tcatccttat gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt
    23521 tgggttagga cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca
    23581 agtaaaagaa gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc
    23641 ctctgtgaag cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat
    23701 cgcccaaaga gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat
    23761 gcaaagcgct gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca
    23821 acgatttatc gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt
    23881 cgtttctgaa acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac
    23941 gaaaatcttt tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca
    24001 agcaaaacga ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa
    24061 ttagaagagt taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga
    24121 acattaccaa gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat
    24181 acagcagatt ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag
    24241 tctacgatcg tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat
    24301 ttgaaaaatt atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca
    24361 gatgacaaat cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct
    24421 tctatccctc acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga
    24481 gcggataaat tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt
    24541 cctttaggtg agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa
    24601 gggaaaaatg tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca
    24661 atcgattttc ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa
    24721 ggtttcttcc atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc
    24781 attcgcgatc atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa
    24841 gaagagttga atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat
    24901 tacaacatga aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca
    24961 atgatcgagc ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca
    25021 aaaatctctt acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac
    25081 ggacgattcg aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa
    25141 attgcagaat tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc
    25201 gtcccaatga tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt
    25261 cccgccctct tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt
    25321 ataacaaaag ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg
    25381 taaaagaaaa gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg
    25441 atgcggaatt agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg
    25501 gagacggcac gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg
    25561 tcggattact tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca
    25621 aaaaagaaga agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc
    25681 aagtcaatga tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag
    25741 tttggatcag tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt
    25801 ttaagttatt gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt
    25861 ggaaaggaaa atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa
    25921 attttgacga ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct
    25981 tagatatttt ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga
    26041 tccccggcat tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg
    26101 tgggcactcg aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat
    26161 caaaaggatt aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa
    26221 cagaaagttg gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt
    26281 ttcattgtga atttttactt attttgtctg atggggtatg ataaacatca ggctagaact
    26341 agcggctggc gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg
    26401 ggaggattga tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata
    26461 ggattcgctg caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca
    26521 ggagatgtcg tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt
    26581 gatttttgcc attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt
    26641 gctgtctacc agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat
    26701 cgctgaaggg cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa
    26761 agatgggttc ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg
    26821 aacgctgatc tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc
    26881 aggggtgaca gcactccata tgattatgta caaactggca gtgatcactt atgcattagc
    26941 tggcttggtc atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat
    27001 catcgctggt atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag
    27061 cttgaatgtt caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt
    27121 gcggaaatgg gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac
    27181 cattatccaa gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt
    27241 attttggtat gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct
    27301 actgaccatt tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc
    27361 tggtattggt tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt
    27421 tgacgcagtt tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta
    27481 tggatttgtg tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt
    27541 aaaaaaagag aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca
    27601 aatcaaagaa aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat
    27661 acatacaatc aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac
    27721 tatgtgtata ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa
    27781 gaaataagtg atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga
    27841 ctacgacgct tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc
    27901 aagatatcga cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa
    27961 atttctatac ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac
    28021 tggatgagta tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga
    28081 atttctttcg attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc
    28141 tttcaacgga agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt
    28201 atttgaataa aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag
    28261 gaggagaaag agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg
    28321 gcgttgattt agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg
    28381 aagaaatccg tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga
    28441 taggagaacc cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac
    28501 gcaaagatgt gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat
    28561 tgatcgctgg agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag
    28621 aagtcaaaaa aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag
    28681 gggcaggaaa aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc
    28741 gcggtgaatt acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa
    28801 aagacaaagc gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag
    28861 atacgatcag tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca
    28921 tccatgacaa cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt
    28981 tcttaccgga caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa
    29041 tgaactctat gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg
    29101 aagaagctgc actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc
    29161 aagaagaatt agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag
    29221 aaaaagaaga agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg
    29281 aattagaaga tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta
    29341 cgatacctca attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga
    29401 ttaagatggt tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa
    29461 cgggtatccc cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg
    29521 aaacacttca taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg
    29581 taattcgttc acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc
    29641 taggaccaac tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg
    29701 actcagaaga tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt
    29761 ctcgtctagt cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg
    29821 aagctgtcag acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc
    29881 ccgatgtctt caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag
    29941 ggcgagtagt agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt
    30001 tactgctgga aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca
    30061 acacgctatt acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt
    30121 tatttacacc attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat
    30181 tggcacaacg tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt
    30241 ggattgctga aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca
    30301 ctaaggaagt agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat
    30361 caaaagtaac gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag
    30421 aaatcgtcta atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt
    30481 cagacctcct tttttcaaat aaacagtgtt ccagaagtag tttcttcgaa aaataagccg
    30541 aaatttcttg aagctgcccg cttctgtcac aacctctttt attaggtatt tttcactttt
    30601 tctaatttat aactttcaaa gtaacgctca tcttttttac tttgagacca tgcaaacaat
    30661 cccattaagg cagcacctat cgtatttgtc agcaagtcgc ccatcgtatc catcaatgct
    30721 gctcgtccga caaacagtgt gccatcagaa gcagcaaaac gttgaagatt catgcctaag
    30781 aactggtcgc ataagaattc ccagaactcc caaaacacgc cgcaaagtcc agcaaacgca
    30841 aagccgaata agaggaacaa ccaaggactg gtttttgata tctcagcatc tttcatcaag
    30901 taaccaatca atccatagcc aagagctgtc aggaccattg gactcaccgc atgtaagatt
    30961 ttgtcccaaa aagagatgat actgatcaaa tgcatccctg tgcctaaaaa gacagagatg
    31021 aacaagaaaa accagtaaaa caaaacgatt gctgctggta ttttaagttt gaaaactttc
    31081 aaaatgactt gtggcatgaa aatcaatgca atccctaata aagattccac gataaatgtg
    31141 attccttgag aagtcgaata tttttgtgtg ataaattcat aaaaattata gcagacaacg
    31201 aatacaccaa aagcaagtaa agctatttgc acctttttga tttctttaat cactgaaagt
    31261 ccctccatct aaaaatcttt ttacttctga aagcaactca atttctgaag aaaccacttt
    31321 tccgttcaat ttgatcaaac ctattgtata taagttcagg tagtgaaatt gattttcagc
    31381 tgtttcttgt agtgcagcga tttttttcgg gtgggttccg ccttgctgtc gagtatcagt
    31441 atataagccg atcactggga tgcctttcgc ataagccaca ccgatttccg atgctacccc
    31501 ggcatcgatc gtcagcccat ctagtaaagc aatcattaaa tcactagcca acactttttc
    31561 tgtgtcagca agagcaatca ttcgactgtc tgcataagca gttttgtcat tgattgcttc
    31621 attttcttga ggaagataga tcgaaagctc agaagagagc tctctgattt ctttaactaa
    31681 ctgttggtta tataacaaat cacttttagc aaacattggt gcggcaaaat aaattttcat
    31741 ctaaacatca tcctttttat caaaaataat cgctaaagta agcttccatg tttggaatga
    31801 tacgctctag tgacttcagt gtttcttcat ctgtttctaa ccgttcgatt cttgccaaat
    31861 aagaagcacg gcgataattc atcatcaagc aagtcaatgt ttggatatcc agtcgaacgg
    31921 attttcctat aggttcattt aagacacgga cttgtccctg ttcatcccat gttaaagcga
    31981 agacaccatt attccaagga gcgacaggat cttcaatgat gaaatgaaaa gcatcagctg
    32041 ttccaacaaa cggaaaccgt tgaaggaatt cttttacatc aacgatccga gccataaaat
    32101 atggttcgat ctgctctttg atctgactat cttcaatcaa aaatgctaaa ggctcatttt
    32161 tataaatatc tccatgtacc cagtagatca tggaaaaatg tgcggaaata aagttccata
    32221 agccatttcg agcttcttga tcaagataga acatttcttt tacgtgaaat atttcttcag
    32281 ctacccagta gaacagaaca cctcttggtt catggttgct atcgtagtag acagcggctg
    32341 tgcgctcatc ttcattttcg aaacgccaat actcttccca atgaaaatca ctgcggaata
    32401 aagcaccatg gttttgttgg gcaaatttgt cataaacgga aaatacgtct ggatgatcaa
    32461 ctggtaatcg ctcaaccata ccacttactg ggatttgttt aggtagctgt gtatctctga
    32521 ttttaaagga aagtttatca gacatgattt cccatccttt acgccgatag taggggatac
    32581 tgtaaggata caaataagag atccattgct tattcttgcg catattatcc aatgcaacga
    32641 taattagatc ttgcatcaat ccatggttag catattctgg ataagttcca actccagtca
    32701 caccacccat tttataacgt gcaccgtgaa tattgacttc acaaggatag atagcgattt
    32761 gagagatcag tttattttcg tggaaccatc cgaacacttt cgatacttcc aaaatcggtt
    32821 ttttggaacg gataaaagct cgtttattct caaacccgct ttcctcgatg tctgcttcag
    32881 tcacttggaa cacataggaa agcaattcat tgaattgatc gatatgttct tgagtgaccg
    32941 gttttaattc aagattttct ctaaaatctt tttgatccat tttttcatct ccatttatta
    33001 gcttgataac agtatagcaa aattctacaa aaaaaacttc tatagctgac taattaaaaa
    33061 ctctttaaat tactgctttt cgttggtata atggaaagtg ctgattatat gaaaagagga
    33121 gacgctatgg atataaagaa aatgaaagaa cgccaagagc agattcgtaa tttttcgatc
    33181 atcgctcata tcgaccatgg gaaatctaca ttggccgatc gtattttaga aatgacgcac
    33241 actgtgacgt ctcgcgaaat gcaagatcag ctgttagact cgatggattt ggaacgtgaa
    33301 cgtggaatca cgattaaatt aaatgctgta gaactcaatt acacagcgaa aaatggagaa
    33361 acatatatct ttcacttgat tgacacccca gggcacgtcg acttcaccta tgaagtctct
    33421 cgaagccttg ctgcctgtga gggtgccgtt ttagtggtcg atgcagcaca aggaatcgaa
    33481 gcacaaacat tggccaatgt ttatttagcg ttagacaatg atttggagat cctgccagtc
    33541 atcaataaaa tcgacctacc cgcagcagat cccgaacgtg tccgtcaaga aatcgaagac
    33601 gtaatcggaa tcgatgctag tgaagctgta ttagccagtg ccaaatcagg gattgggatt
    33661 gaagatattc tcgagcagat cgtggaatat gttcctgcac caagtggaga cttagatgca
    33721 ccgctaaaag ctttgatctt tgactctatt tatgatagtt accgcggtgt tgttctaaat
    33781 gtccggatca cggacggtat ggtcaaaccc ggagacaaaa tcaaactgat gagtaatggc
    33841 aaaacatttg atgttacaga ggtcggggtc ttctcgccaa aagcagttgc tagagacttt
    33901 ttgatggtcg gtgatgtcgg ttatatcaca gcaagtatca aaactgtcca agatacacga
    33961 gtaggggata cagtaacgtt agcagacaat cctgccgctg aagctttacc aggttaccga
    34021 aaaatgaatc cgatggttta ttgtggtctt tatccaattg atacttctcg ttacaacgat
    34081 ttgcgggaag ctttagaaaa actgcaattg aatgatgctg ctttacaatt cgaaccagaa
    34141 acctctcaag cattaggttt tgggttccgc tgtggattcc tcggacttct tcatatggat
    34201 gtcgtccaag aacgcttgga acgggaattc aatctagaat tgatcacgac tgcaccatcc
    34261 gttatttacc atgttaataa aacggatggt acgactgcta cagtagataa cccggcagat
    34321 tttcctgaac ctgtaacgat tcaggatgta gaagaaccat tcgtcaaagc acagatcatg
    34381 gtcccaaatg attttgtcgg tgcagtaatg gaactttctc aacgaaaacg gggagaattc
    34441 attacgatgg attatttaga tgattaccga gtaaatgtcg tctataatat tccgctttct
    34501 gaaattgtct ttgacttttt cgacaaattg aaatcaagca cgaaaggcta tgcctcattg
    34561 gattatgaaa tgtctggtta tcaaaaaagc aagttagtga agatggacat cttgctgaat
    34621 ggagaaaaag tcgatgcatt aagctttatc gttcaccgag actttgccta tgaacgtgga
    34681 aaagcaatcg ttgaaaaact gaaaaaacta atcccacgcc aacaatttga ggtgccaatc
    34741 caagcagcta ttggacaaaa aatcgttgcc cgttcagaca tcaaagcctt gcgtaaaaac
    34801 gtcttggcta aatgttatgg tggagatgtt tctcgtaaac gtaaactctt agagaaacaa
    34861 aaagaaggga agaagcggat gaaacaaatc ggctccgtcg aagttccgca agaagccttc
    34921 atggccgttc tgaaaatgga tgagcaagat agtgtgaaat aacttataat caatcgaaaa
    34981 acctattaaa taaacctttt tgagtagatg caacactgag gattatctgt ataaaagatt
    35041 ttaaactgtc atttggttat cacggcgata ctaaaattaa caaaattgga atatttttct
    35101 tgaagatttt tagctgtcag tatatgatga aagcatctca taggaggtgc ttttttcatg
    35161 gttgataatt caagtggaag ggttcttaaa tctctaagaa aagagaaaaa actatctcaa
    35221 aaaaagttag ctgatttagc aggtatttca caaagtactt tagttaaata tgaaaaaggg
    35281 tcaagaaaaa tccctaaaga cgtagataat actctaagca agattctgaa tatagaaact
    35341 ctaataaaag atgaggaaga taagattgag attctcatcg gtaaactaat tgcatacaga
    35401 gatatgaata agttacttaa caaagagtta gctgataata taggaattag tgaagtatta
    35461 ctcagttatg tgttaaatag aaagagaaat ccgtcaaaag aaatgcaaaa aaaaatcgat
    35521 atttttctat taagtaatga aaaagaaatt ttgaaggaga ttaatcgtga tagtgagata
    35581 tttagtttat caaaagacga taaaattgtt atgggaaaaa gaatacgaga agtccgaaag
    35641 aaccgggaag agacgcttga aaaatttggt aaaaacttta ccatctatac aggcaaaaat
    35701 gttataagta gatgggaaaa aggtattaat attccagata ttgaaaaact aatgaatatt
    35761 gcctatcttg gtaaggtcac tgttccttac cttatgtacg gagaagatta taagaatata
    35821 cttccaaaag atgaaagagt tagcgatttt aaaaagataa attcttttag tatgggatta
    35881 aggatgagga aaattaggaa agattattat ctagaaaggg aggagtttgg aaagcttttt
    35941 tctccttcaa tttcaaaatg gtccatagat aggtatgaga atggtagaga tatacccaat
    36001 actaatcgaa ttatccaata tgcttatata ggaaatcttt ctttagaatt tttgatttac
    36061 gggatataaa aatagtttac gtcgatactt attaagttat cgacgttttt tattatagaa
    36121 aaaatttata aaaggaggtt tcttgatatg ataagaaaca aaaagggttt gttgaaagtt
    36181 gctttactgg cagctttttt ctaagtaact ttttgacaag ctcaatggca acacaagcgg
    36241 aagaagtaat acaagaacta actgttatga ataacagcta gataaaatgg gctatgtatg
    36301 ttatccaaca atttagtaat cactagaagc ctagcgaaag ttcgcttgat aagttataga
    36361 tgagtattga tttgtagtgt ttccaaatca aaagggtaca gagccacatg aaatatgttg
    36421 tcctctgcag cgtcaggatg ggaatccata ccatggagat tcggagatct gtgagggaat
    36481 acttacgtgg ttaatatgtc agttgtgttg gacgtagtaa tggtcatagt gggtagattg
    36541 actgaattct tatatgagaa aatgaaacca acaagaagat agggttattt atacagaatt
    36601 ggggatcttt tctggaaaag taatcggata atgcgagatt cgtacggtct tttttaaatt
    36661 tctctaaaaa aaacggcatc gaatgggttg ggtgattgat aagcaatgaa tcatagactg
    36721 atatagaata aaaaatgatt ctatttatct ttttacatct atcgtttttt caagtagccg
    36781 caaattatat cagcattcaa caatttttgt atacaagttc tagtaaaagg atctgaagaa
    36841 aaagttggtt gttgtgaaga taaaaaaaga atcaggtttt actgagtttt tcttcaaaat
    36901 ttgtgttatt aggttaggac aaagataaga agaagtatga agatttaaaa aaggaatgag
    36961 gaaaagatag taatttccga ttattggagt ttttttat
//
LOCUS       DAZKCH010000019        36826 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000019 DAZKCH010000000
VERSION     DAZKCH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.019"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..1663
                     /locus_tag="ACG84X_000972"
     CDS             2..1663
                     /locus_tag="ACG84X_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9126869.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1733..2080)
                     /locus_tag="ACG84X_000973"
     CDS             complement(1733..2080)
                     /locus_tag="ACG84X_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFP9126870.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2164..3105
                     /gene="opp3b"
                     /locus_tag="ACG84X_000974"
     CDS             2164..3105
                     /gene="opp3b"
                     /locus_tag="ACG84X_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFP9126871.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3106..4149
                     /locus_tag="ACG84X_000975"
     CDS             3106..4149
                     /locus_tag="ACG84X_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9126872.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4155..5225
                     /locus_tag="ACG84X_000976"
     CDS             4155..5225
                     /locus_tag="ACG84X_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126873.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5215..6168
                     /locus_tag="ACG84X_000977"
     CDS             5215..6168
                     /locus_tag="ACG84X_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126874.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6180..7190
                     /locus_tag="ACG84X_000978"
     CDS             6180..7190
                     /locus_tag="ACG84X_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFP9126875.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7475..8296)
                     /locus_tag="ACG84X_000979"
     CDS             complement(7475..8296)
                     /locus_tag="ACG84X_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFP9126876.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8393..8671)
                     /locus_tag="ACG84X_000980"
     CDS             complement(8393..8671)
                     /locus_tag="ACG84X_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126877.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            8939..10948
                     /gene="metG"
                     /locus_tag="ACG84X_000981"
     CDS             8939..10948
                     /gene="metG"
                     /locus_tag="ACG84X_000981"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFP9126878.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11427..12014)
                     /locus_tag="ACG84X_000982"
     CDS             complement(11427..12014)
                     /locus_tag="ACG84X_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126879.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12189..13511
                     /locus_tag="ACG84X_000983"
     CDS             12189..13511
                     /locus_tag="ACG84X_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFP9126880.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13666..14442
                     /locus_tag="ACG84X_000984"
     CDS             13666..14442
                     /locus_tag="ACG84X_000984"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFP9126881.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14435..15004
                     /gene="rnmV"
                     /locus_tag="ACG84X_000985"
     CDS             14435..15004
                     /gene="rnmV"
                     /locus_tag="ACG84X_000985"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFP9126882.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            14997..15881
                     /gene="rsmA"
                     /locus_tag="ACG84X_000986"
     CDS             14997..15881
                     /gene="rsmA"
                     /locus_tag="ACG84X_000986"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFP9126883.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16332..16961
                     /locus_tag="ACG84X_000987"
     CDS             16332..16961
                     /locus_tag="ACG84X_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126884.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17085..18194)
                     /locus_tag="ACG84X_000988"
     CDS             complement(17085..18194)
                     /locus_tag="ACG84X_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126885.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18403..18825
                     /gene="mgsA"
                     /locus_tag="ACG84X_000989"
     CDS             18403..18825
                     /gene="mgsA"
                     /locus_tag="ACG84X_000989"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFP9126886.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19012..19110
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19148..19684
                     /locus_tag="ACG84X_000990"
     CDS             19148..19684
                     /locus_tag="ACG84X_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFP9126887.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(19724..21487)
                     /locus_tag="ACG84X_000991"
     CDS             complement(19724..21487)
                     /locus_tag="ACG84X_000991"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126888.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21490..23205)
                     /locus_tag="ACG84X_000992"
     CDS             complement(21490..23205)
                     /locus_tag="ACG84X_000992"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9126889.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(23984..24208)
                     /locus_tag="ACG84X_000993"
     CDS             complement(23984..24208)
                     /locus_tag="ACG84X_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126890.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24399..27176
                     /locus_tag="ACG84X_000994"
     CDS             24399..27176
                     /locus_tag="ACG84X_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9126891.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27257..27676
                     /locus_tag="ACG84X_000995"
     CDS             27257..27676
                     /locus_tag="ACG84X_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9126892.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27688..28158
                     /locus_tag="ACG84X_000996"
     CDS             27688..28158
                     /locus_tag="ACG84X_000996"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9126893.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28175..28954
                     /locus_tag="ACG84X_000997"
     CDS             28175..28954
                     /locus_tag="ACG84X_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFP9126894.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            28941..29762
                     /locus_tag="ACG84X_000998"
     CDS             28941..29762
                     /locus_tag="ACG84X_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9126895.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            29779..30828
                     /locus_tag="ACG84X_000999"
     CDS             29779..30828
                     /locus_tag="ACG84X_000999"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9126896.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            30841..31845
                     /locus_tag="ACG84X_001000"
     CDS             30841..31845
                     /locus_tag="ACG84X_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9126897.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32478..33497
                     /locus_tag="ACG84X_001001"
     CDS             32478..33497
                     /locus_tag="ACG84X_001001"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFP9126898.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            33540..34421
                     /gene="galU"
                     /locus_tag="ACG84X_001002"
     CDS             33540..34421
                     /gene="galU"
                     /locus_tag="ACG84X_001002"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFP9126899.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            34721..35098
                     /locus_tag="ACG84X_001003"
     CDS             34721..35098
                     /locus_tag="ACG84X_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126900.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            35704..36318
                     /locus_tag="ACG84X_001004"
     CDS             35704..36318
                     /locus_tag="ACG84X_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9126901.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT        12044 a         6456 c         7544 g        10782 t
ORIGIN      
        1 aatgaaaaag aaatttacat ttggtttggt tgcggtatgc ggccttgtac ttgctggatg
       61 ttatggcggc agttcagcca caagcagtag ttcagcaaaa agcggttcag cagatggagg
      121 aggcgtattt aacttagtcg tgcctcaaga aatgcctaca gctgacttat cagttgcaac
      181 agatacaatc agttttacag cattgaataa cgtttatgaa ggaatttacc gtcttgatga
      241 agacagcaaa ccacagccgg caggagctag cgagttggca gaagtcagtg aagacggatt
      301 aacttacaaa atcaaattac gagaagacgc aaaatggtca aatggtgatc ctgttacagc
      361 agcggattac gtttatggct ggcaacgaac agtagaccca gctacagctt ctgaatatgc
      421 ttacctgtat gcgccagttg aaaatgcaga agacattaca gctggaaaga aagataaatc
      481 agaactaggg atcaaagcag ttggtgacta tgaattagaa atcaaattga cgaaacaaac
      541 accatatttc caatatctgc ttgctttccc atcatttttc ccacaaaaac aatccgtagt
      601 ggaagaaaat ggggatgcct atgcatctgc aagtgataaa gctgtttata atggaccatt
      661 cacattagaa gattttgatg gaccaggaac agatacagaa tggacttata agaaaaatga
      721 tcattactgg gacaaagata cagtaaaact ttctgaaatc aaagtcagtg tagtaaaaga
      781 atcttctact gcattgaact tattcaaaga tggccaagca gatgacgtga tcttgtctgg
      841 tgagttagca cagcaaaacg caaacgatcc agcttatact tctgttaaag aagcgcggac
      901 aagctatatc gaattcaatc aacgtgaaaa gaattcacca ttcaacaatg tgaacctaag
      961 aaaagctatt tcttattcta tcgatcgtga agctttagta aaacaagtac taggtgacgg
     1021 atcagttgtc tctacaggat tgatcccatc agatatggta aaaagtccaa caacgaacga
     1081 agactttgca aaagaagctg gaaaattagt ttcttatgac aaagataaag caaaagaata
     1141 ttgggaaaaa gcgaaaaaag aattgggcgt tgattcttta gaatttgatt tgatggcttc
     1201 tgatgatgat tcatcgaaaa aagtaatcga atatgttcaa aactcaatcc aagaaaactt
     1261 ggatggcgta acagtcaaac caacacctgt tccattctct gtacgtcttg accgctcaac
     1321 ttcgggtgat tttgacgcag tactaggcgg atgggctgct gactatgcag acccaagcag
     1381 ctttactgat ttgtttgtca caggtaattc atacaaccgt ggtcgctgga gcaatgcaga
     1441 atatgacgaa gcagttaaag cagcttcatc aacagacgct ggcgatgaac aagcccgttg
     1501 ggatgatttc caaaaagcaa tcaagatcat ctctgatgat atgggtgtcg ttccggtgta
     1561 ccaaaaagca gaaggtcacc tagtgaatga aaaaatcaaa ggtatcgttc accatgcggc
     1621 aggcgcttca tgggattaca aatggacata cgttgaagaa taatcgttaa taccgtgagc
     1681 atgagaaaaa acgaggctgc ggcaaatgtc gcaacctcgt tctcatattc acttatccta
     1741 acaaagaaaa aagcatgaaa atagcagaaa gagcaattag tattccggca atgatcagcc
     1801 aaaagctgta cataccgtag ctggcagacg agagcgagga aaattctggt tttttctttc
     1861 ggttccttgt tcgtgcaaga tggaccgatc gctgaaaatg atcgaagaaa cccgaagaaa
     1921 agacccataa aaaaccgccg ataatcagaa acggcaatga ccataagaat agatcattag
     1981 ataattgaat gagtgtaaag gaatggttga tgagattttt tattaaaata accagaatca
     2041 gtagaaaagc tactgcgtag gggatagatt tttttttcat ttgattgctc ctttattttt
     2101 ggttcattat ctaataatgt agcgaaacat ctgtcagaag tcaaaagcta gggggaaaca
     2161 ttagtgaata gttatatcaa atatgtatta aaacgtgtct ttttcatgat catcacgctt
     2221 tggttaattg caacaatcac ctttttcttg atgcaattgc tgccgggcac gccatatacg
     2281 aatcaggaac gtttgagtcc tgaaacaatc gagatgctaa ataaacaagt cggtttggat
     2341 aaaccagtta tcgtacaata tgggatttat ctttctaatt tgcttcaagg agattttgga
     2401 atttccttcc aatttaaaaa ccagccagtc gcacatttgt tagctggaag aatcggacca
     2461 tccttgcagt tagggttaca ggcaattatc tttggaacag tcctagggac gattttagga
     2521 acgatctctg ccatgaagca aaatacatgg gcagatacat cttctacact cgtagcgata
     2581 ttaggtcgtt ccattccaaa ctttgtattt gctgttttat tacaatatat ctttgcaatc
     2641 aaattacaag ttttgccaat cgcaaaatgg gatggctttg tgtacacaat cttaccaaca
     2701 attgcgttgg ccatgtcgcc gcttgctgac tctgctcggt ttatccgtac ggaaatggtg
     2761 gaagtactgc atagtgatta tgtggaatta gcaaaagcaa aaggattgag ccgttgggaa
     2821 atcgccttta aacatggtct tcgaaatagt ttgattccat tgatgacttt attaggaccg
     2881 ttagctgtag cattgatgac cggatcactg gtggtagaaa atatctttgc tattcctggt
     2941 atcggggaac aattcgttaa gtcaatcaca acaaatgatt atcctacgat catggctgta
     3001 acgatccttt actcatttat gctgattttt gttattttga tcgtggatct attgtacggt
     3061 ctagttgatc caagaattcg tgtttcagaa gggagccgag gataaatgga aatgatacca
     3121 aagcgttatg aaacagttgc agatatccct gcggatgaat ttcttccatt acaaaaaaat
     3181 accgaagaag aacgtgaaca gattactgca ccttctttga attttatcca agattcatgg
     3241 cgccgtttaa agaaaaacaa agctgccgtt atttcaatgg ttttactatt ggtcatcatt
     3301 ttgatctctg tgatcacaat ctttgtttct cctcatgatc caactgccca aaacgtggct
     3361 tatatcaatt tgcctcctcg tattccggga atcaatatcg atggattgaa tggaaaagca
     3421 atggttggtg gtgaacttgt tgataaatat gctcaagcaa acgtcccttc aaacgtaaat
     3481 ttctttttag gaacagacgg tttgggacgt gatgtattaa gccgcttatt tatgggaatg
     3541 agaatctcgt tgctgatcgc atttattgct gcattactag atgtaacgat tggtgtagct
     3601 tacgggttgg tttctggttt gttaggcgga cgtgtcgata acgtgatgca acgttttttg
     3661 gaaatcttat caggaattcc aaacctcgtt gtcatgattt tgatgttggt cgtttttgaa
     3721 ccaggaattt tttcaatcgt ggctgctatg gccatcacaa actggatacc aatggcacgt
     3781 atcgttcgtg cacaaacaat gaaattaaaa gatcaagaat atgttttagc tggattgaca
     3841 ttaggtgaat caagaatgaa aattgcattc aaacatattt tgccgaatat ctctagtgtc
     3901 attattattc aaatgatgtt tagtattcca tctgctattt tcttcgaagc ctttttaagc
     3961 tttatcggtt taggtcttac gcctccgtca gcttcattag gaacgatgtt gagcgaaggg
     4021 tacaagacat tcctgtatct gccttatcta ttatggattc cggcagtaac tttatcggtt
     4081 atcatgattg gctttaactt acttgctgat ggattgcgtg atgcctttga tcctaaaatg
     4141 aaagagtgaa gacgatgacg aaaattttag aagtgaaaga cttagaaatc tcttttgata
     4201 cgtatgctgg aaaggtacga gcgattcgcg gtgtcaattt tcatttgaat aaaggagaaa
     4261 cattggcgat cgttggggaa tctggaagtg gaaaatcagt gacgaccaga agcatcatgc
     4321 gcttgctgtc aagcaacgcc aatatagatg ctggtcaaat cctctttaaa ggtaacgata
     4381 tcgttggaaa atcagaaaga gagatgcaaa aaatccgtgg taaagaaata gcgatgattt
     4441 tccaagatcc aatgacctct ttagatccga cgatgcccat tgggaagcaa gtcgctgagt
     4501 cccttagaaa gcataataaa gtttcaaaaa aagagggaca aaaagctgca ttagaattgc
     4561 ttaaattagt tggaataccc gaagctgaga aacgtatcaa cagttatccg catcagttct
     4621 caggaggtca gcgtcaacgg atcgtgatcg cgattgcact ggtatgttat ccggaaatac
     4681 tgattgctga tgaacctaca acagcgcttg atgtgactat tcaagcacag attttggagc
     4741 tgctgaaaga aattcagaca aaaatcgata catcaattat ctttatcact catgaccttg
     4801 gtgtagtagc gaatgtcgct gatcgtgtcg ctgtcatgta tggaggaaga atcgttgaag
     4861 ttggaacatc ggaagaaatt ttctacaacc cgcaacatcc ctatacttgg ggactgcttg
     4921 gttcaatgcc gacattagat agtgcgaacg atcgattgta tgctattcct ggttctccac
     4981 cggatttatt gaacccgcca aaaggagacg cattctatcc aagaaatgaa ttcgcgatga
     5041 aaatcgatgc agaacaagaa ccaccatttt ttgaactatc aaaaacacac aaggcagcaa
     5101 cttggctact tgctccgcag gcacccaaag tgacaccgcc agaagaaatc caacgtcgct
     5161 gggctatctt taaagagaaa caaaaacata cttacggtca aggaggaatt gctgatgcca
     5221 aataaactac ttgaagttaa aggattgaaa cagtatttca atgtaggaaa aaagaatgaa
     5281 gtacatgctg taaatgacat cagctttcac atttatgaag gagaaacatt cggtttagtt
     5341 ggagaatctg gaagcggaaa atccactact ggccgtacga tcattcgctt gaatgaacct
     5401 actgatggtg agatattatt cgacggtcaa gatataacga agatcaaaga taaaaaaggt
     5461 ttgacgaaat tccggcatga tgttcagatg atctttcaag atccatacgc ttcgttgaat
     5521 cctcgtatga aagtcagaga tatcattgcc gaaggaattg atgttaatgg actagctaaa
     5581 tcatctgaag agcgtgcaaa aaaagtcgat gatctattga gaactgttgg attgaatcca
     5641 agccacggta ctcgttatcc tcatgaattt tcaggtgggc aacgccagcg tattggtatt
     5701 gcacgagcat tggcagtaaa accgcgtttt atcatttgtg atgaaccaat ttctgcacta
     5761 gatgtgtcga tccaagccca agtggtcaat ttgttgcaag atctccaaaa agaacatcaa
     5821 ttgacctatc tatttattgc acatgatttg tcgatggtta aacatattag tgaccgaatc
     5881 ggtgtaatgc ataacggctt gttattagag atgggaacaa gtgatgaaat ctataatcac
     5941 ggtgttcatc cttatacaga aagtttgtta tctgctattc ctctaccaga tccagaccat
     6001 gagagaaaac gcagaagaat caaatatcaa cctgaaccag atgacggaca agtacgtcaa
     6061 cttcgtgaaa tcgcaccaga acattttgtc tatgcaactg agcaggaagt cccatattac
     6121 gcaaaaaaac taaaacgaca aaaggaatct cttctggttg ctaactagga gggacataga
     6181 tgctaaaagc ttttaaattc cgtatgtatc cgacagaaga acaaaaacag caattgattc
     6241 gtacttttgg atgtgctcga tttacctata accatttgct gaaaaagcgg cagaaaagtt
     6301 ggcaacaaac aggagtagcc aatttttcgc tcacacccgc tacattaaaa aaagaatacc
     6361 cattcttaaa agaagtagac agtcttgctt tagcaaatgc acagcttaat ttggatcggg
     6421 cttttcgcaa ttatttcaag ggacgtgcca gcttcccaaa gcttaaaacg aaaaaaagta
     6481 tgtggcaatc ttatacgacc aacaaccaaa cccgtacgat ctatctggaa aatggctact
     6541 taaagttacc aaaacaaaaa gaactaatca agataaatca gcatcggcca gttgaaggat
     6601 cgattcgctc cgctacgatt tctgctcgat ataatgaaga attttatgtc gcactacttt
     6661 gtgatgtttc gccagtaaaa aaagaatctt tagctaaatg gatcgggatc gcctatcatc
     6721 cgaagacatt gatccaaaca tctcgacctc tagaagtaac tttaccaaaa tttcaccaga
     6781 cagaagaaaa gctgcaacat gcacagcgga aattgaatgt gaaagtccgc tccgctcacc
     6841 atagaaagat caggttagat caggcaagca attatcagaa acaaaagaga aaagtaatgg
     6901 atctttatct gaaacaaaag aaccagcgag aagattatct tgaacaatta tctgggaaat
     6961 tggtcaaaca atatgactac ttatttgtag aatcttttcc aaaagaagag gcacatgctg
     7021 atttttctat tcacgactgg cataaattaa taacaaaatt gcgttataag tcccaatggt
     7081 ataataaaaa atttcttttg atcaataccg acggagcaga agaaagcaat tccgtaagaa
     7141 agagccaagt agtagaaaaa atgggcagac attcggttat caagggataa aaaatgaatg
     7201 aaactgatag gagcgttagg gttagccttg ttaataaaaa gtcttaatga cttttgtttc
     7261 taggaatttt tcttttgaag aaaagctcac taattatgac aaaccaataa aacaatagca
     7321 gaaaaagttc gtacgagctt tttctgctat tgttaatttt ttattcagaa agtttacgaa
     7381 tacatcaaaa ttctgaaaca aaaaacgtaa ctcacaaaga gttgtttttg cgttttttct
     7441 tgaatgatta ggtctgaatc ttttgctcac aaccttattc atggtgcccc ggcttgagct
     7501 gatagatttt tgaaggacgg ccgattccta caggacgttc accgatctca tcgaaatatt
     7561 ggagcatagc tttcttaaaa ttggaatgat cgatcgtttt ataatcgatc cctaagaatt
     7621 tagcaaatac ttttcgagct tccgtaatcg tgaaatcttt acctaaaact tgtagaactt
     7681 gcggctcgtg ttccatttta ttgactacac ggttgaatgc tttcaagatg atttgactat
     7741 ggtcaaaagc caaagtatct ttgccagaag actctccagt gactaaatca agcgagatag
     7801 ccacttctcc gctagataaa tggatcttgt tactatgacg ttctagtgtg aaccagcgta
     7861 cttccttggc atcatctccg gcgattagcg gttcttctcc aataaaggct aagtagctga
     7921 ctgtgacgac ccagcctcgc ggatctcgat taggcgtact gaatgtatgc agttgctcaa
     7981 tattttcttt tgaaataacc acaccagttt cttcctttgt ttctcttaag acgctttctc
     8041 cagttgactc atccttttgg acaaagccac caggcaatgc ccatgaattt cgataaggat
     8101 gcccttttct ttggatcaac aaaactttca gctgatcttc ttctttgtta tagcacatca
     8161 gtacgatatc gacagtcaaa gagggcttgt catattctgg acgttcctgt ttttgatacc
     8221 agttaagaaa ttcttcttca cttgctttat gttcataata taatttttct tcttctttag
     8281 aagcaaaacg gttcatctga ccacctccat tgacagtaaa agtacttttt accttattgt
     8341 agcagactct gaaaaaaaac caaggattta cttgaaaaat ctaggttatc atttaaatat
     8401 gaaaaataaa tggaagtatg agattgaata aaaagaaaag cagataaaac ggcaatactt
     8461 tataccgctc ttcacgaatg gcaaagaagc cacaaataac gatatatacg tcaatgataa
     8521 aacgcaaaat ccaagctgct gtcataaaac tgttcaaatg cccatggagg ttaaaataac
     8581 catacatacg aatataaaaa tagctgaata ttaaatgtgc taatgaaaga aaagcaatac
     8641 taagtgtaaa aaaaagatgt ttcttctgca tgattgttcc agtcccttac taagatagat
     8701 agtctttatt ataccacgtg tgaggggaga aataaaaagc cgttttttag tagatatgaa
     8761 acaaaacaaa aacccgcatt tattcaacct attcatcctt ttaaaggata gattgaacgt
     8821 agatagaagt cgtttatcca gtctttttca ttttgaaaaa aagctaacag catgcttttt
     8881 ttatggtata ctagcaagga aacgaattcg catcatgcga taaaggagga agagccccgt
     8941 ggcagaaaag gaaacttttt atatcactac gccaatctat tatccaagcg gcaaacttca
     9001 tatcggcaac tcgtatacta cgattgcatg tgacgcaatt gctcgttata aacggttgat
     9061 gggctttgat gtgttttatc tcactggagt ggatgaacat ggtcaaaaaa tcgaaacaaa
     9121 agcagaagaa ctaggtgtaa aaccgcaaga atatgtagat aaaatggcgg ctgatgtcaa
     9181 gaaattatgg aaaacgcttg atatcagtta tgataaattc attcgcacga cagatgatta
     9241 ccataaagca gctgttcaaa aaatatttga tcgtttatta gaacagggag atatttactt
     9301 aggtgaatat gaaggctggt actctgtttc tgacgaagaa ttctttacag aaacacaact
     9361 tgcagaagtg tacaaagatg acgaaggtaa cgtgatcggt ggtaaagcgc caagtggaca
     9421 cgaagtagaa ttggtaaaag aagaatcata cttcttccgc atgagcaaat acgcagaccg
     9481 tctattggaa tactatgaag aacatcccga attcatccag ccagaatctc gtaaaaacga
     9541 aatgatcaac aactttatca aaccaggatt agaggatctt gcagtttcac gaacaacttt
     9601 tacttgggga gtaccagtca agagtgatcc gaaacatgtg gtgtatgtat ggatcgatgc
     9661 attatccaat tatattactg cactaggata tggctccgaa gatgaaagtc tattcgaaaa
     9721 atactggcct gcagatgttc agatggtcgg taaagaaatc gttcgctttc atacgatcta
     9781 ttggccaatc atgctgatgg cccttgattt gcctctacct aaaaaagtat ttgggcatgg
     9841 ctggctattg atgaaagacg gaaaaatgtc taaatcaaaa ggaaatgtcg tttatcctga
     9901 aatgcttgtg gaacgttatg gtttagatgc actccgttat tatttgcttc gtgctgttcc
     9961 gtttgggtca gatggtgtct ttacgccaga agattttgtt tcccgtgtca attatgatct
    10021 ggcaaatgat ctagggaact tattgaatcg aacgattgct atgatcaaca aatattgtga
    10081 tggactcgtt cctgactatg cctcacttgt cactccattt gatagtgaac tgtctacgac
    10141 ggctgctaac gttgtcggac gttaccatga tgcaatggaa aaaatggaat tcaatacagc
    10201 attggctgaa atctgggtgc tgatttctcg tgcaaacaaa tacattgatg aaacagaacc
    10261 atgggtatta gcaaaagacg aagaaaagaa agctgaattg aatagtgtca tgatccattt
    10321 agctgaatct ttgcgtatcg cagcgatatt acttcagcca atcatgacag aaacgccaga
    10381 gaagatcttc aatcaactag gattggactc tgaaacaatg aatcttgaag gattacactt
    10441 tggcgaattt ccttcaggaa caaaagtagt tgcaaaaggt acaccaatct tcccacgttt
    10501 agatatggaa gaagaagttg cttttattca agaaaaaatg tctgaaggta ctcaaacaaa
    10561 cgaagataca gtcaaatggg atccagaaga aacagaactt gtttcaacga aagaaaaaca
    10621 aatcaaattt gatgtatttg aaaaagtaga actaaaagta gcagaagtca tcaactgtca
    10681 aaaagtagaa ggggcagata agttgctgca attccgacta gatgctggag acagccaaga
    10741 ccgtcaaatc ttgtcaggaa tcgctgaatt ttatcctgat ccaagcgaat tgatcgggaa
    10801 aaaagtcgtc attgtagcaa atctgaaacc acgaaagatg cgtggacaaa tcagtcaagg
    10861 aatgatcctt tctgcagaag caccagatgg ctctttacaa gtaatcgaag caccaaaatc
    10921 catgccaaat ggctcagaaa tcgcatagaa attcaaaggg ggtatgacac tagttgtgtc
    10981 ataccccctt tttccgaaat ttgagaagca attttcgtaa attccttctt attacttgaa
    11041 gccaatcata taatacagaa acagagaact atccaaaata aatcctagaa aaagaagtac
    11101 gagcttcgct gatttttgtt aatttagaat aatactaata ggaatcgtaa aaacagaaaa
    11161 aaagcataat gataaagggt cgggcagatt ttaattgatt catctggtac tcttttttat
    11221 tgtccttaca ttcataaagt ttgaatgcaa tgactttatt acatctatat ttatatctaa
    11281 cagtagcgtt gatgtgttaa ttataagttc tatcacttta tgttcaatta gtttgtgctc
    11341 ttatatgtgt gattgaaaat atagataaaa aaacaatcat cggctttgac ttcgatgatt
    11401 gttttcttta ttttgtaaaa atcctatcac ttgattttat ggtaaccttt tatttttgtc
    11461 ttcaaacggc ttggtaagag agcagtaagc agtgcaaatg ggatcgaaaa gacataccag
    11521 aaaatcgtac gtccgatacc ataatgttga tagagctttg tcaacatcac gtgtaacaag
    11581 atcaacccta aaagcaagga gccagctata aaccaatgat tatcccaatg catgacttca
    11641 ctaagtgcca tcactccaaa aggatagaaa taaaaataga tcccgactaa ggtcatccgc
    11701 cagttctttg taaatgttcc gatattcaat aaaaagaaaa tcgctgaaag caaaataccg
    11761 ataggcggaa aaagcccaac caaaaaggaa tacaacatcc cccacaagat catcacagga
    11821 cctttgatca atgcaacgat tgcgatgaac aaagtcagca atattagttt ttgtgataac
    11881 gttgcaacag tcattaatcc aaataaaatt aatgtgaacc aatgccaatg ggactgctgt
    11941 tgttctttac gggaaaaatc gacccggttg gataaataat ctgctaattt cggataagaa
    12001 cgcttaaaat ccataaactg ttcctccttc gtggaaaagg taggtttagt atacgaaaaa
    12061 taaaaaagaa atacatccgt cttaagaggg agtttttcac tgaaagtgga gaaaaaagaa
    12121 tggtaaatta aaatattctc agttatactg aaaattatac caaatttcaa agaagaaaga
    12181 ggatgggaat gaaaggcaaa ctaaaacgag aaatcaatct gtttggcgca ttagctaccg
    12241 ttatgggaac cgtgatcggt gcaggcgtct tcttcaaaac tgctgctgtt actgctagta
    12301 ctcagtctac aagtttgaca ttgctagctt ggcttttggg tggtttctta acgatctgtg
    12361 ctggattgac agtggctgaa ttagctacag caatcccgga aactggtgga gctgtaaaat
    12421 atattgaagc tgcgtatgga aaattgccca gctttttatt aggatgggcg caaagcttga
    12481 tttactttcc tgctaatatt gctgcattat cgattatctt tgcgacacaa ttgacgaact
    12541 tattacaatt atctaccgat tatcttttgt tgattgcagt gatcaccgct gtttctgtga
    12601 cagggttgaa tttgttaggg acaaaagtcg gtgcttctgt acaatcagtg acgttgattg
    12661 ttaaattaat accaattgct gtgattgtca tatggggatt attgacccca ggacaaggaa
    12721 ctgtccagtt atttccaatc gaagctggaa aagatgttac ttttgtcgaa ggattgagca
    12781 gtgcgttgtt agcaacgttg tttgcttatg acggctggtt aggtgtcggt gcaatggcag
    12841 gggaaatgaa acggccggaa aaagatttgc ctaaagcaat tattcttggt ttgagttttg
    12901 taacagtcgt ttatctattg atcaattttg tttttttgaa aactttgccg attgatcatc
    12961 ttgccggtaa tttgaatgca gcttctgaag catcagacgt catttttgga ggaatcggtg
    13021 gaaagctggt cactattggg atcttgatct cggtatacgg tgcattgaac ggttatacac
    13081 taactgggat ccgcgtgcct tatgcgatgg ctttagaaga cgagctacct ttcagtaaac
    13141 agctgacaaa gctttcaaag aagtttacgg ttccttatgt tcctgcggtt ttccagttag
    13201 cagtagcttg tattatgatg agccttggtt ctttcgactt tttaacagac atgttgattt
    13261 ttgtgatgtg gctattcagt ttactgattt ttatcggtgt ctttatttta agaaaaaaag
    13321 cgccggaatt gccacgtcca tataaagtac cactttatcc aatcgttccg attattgcga
    13381 ttctcggtgc tattttcatt ttaggtatga cgatgatgac gcaaacgaaa ttagcattga
    13441 tcggtatagg tgttaccttg ataggtatcc cagtctatta tcaaaaaaag aaaaaacgct
    13501 cagaagagta aaatatttca acaacagaca gaaaaagtac gaactaggtc ctctagatct
    13561 tcgtgctttt tctatttcaa taaaacaagt tcttctattt tgatttttgc tacttctgca
    13621 agtagtgctt atgtgctaaa gtaagaatga aaaggagaga taaacatgat atttgattct
    13681 catacccatt taaatgctga acagttcaat gaagatattc cagaaacgat tcagcgagca
    13741 caagaaatgg gggtaacgaa aatggcggtc gtgggcttcg atacgccaac gattgaaaag
    13801 tctttgcaat taagccatga ctatccaaat atatacagta ttatcggctg gcatccgaca
    13861 gaggctggca gttatacgaa agaaatcgaa aataaattac aagaacaatt gactttacca
    13921 aaggttgtag cattagggga aattggcttg gattatcatt ggatggaaga cccgaaagaa
    13981 gtccaagata aagtatttcg cagacagatt gctatcgcaa aagaaatgaa cctaccaatc
    14041 agtattcata ctagagaagc acttgaagac acgtatcaaa tcctaaaaga agaagatgtt
    14101 cgagatatcg gtggaatcat gcatagtttc agtggtgatt atgaatgggc aaaacgattt
    14161 cttgacttag ggatgcatat ttcatttagc ggtgtcgtca ctttcaaaaa agcattagac
    14221 gtccaagagg ctgcagcaaa tgtaccaatc gaacgattac ttgtggaaac agatgcccct
    14281 tatctggcac cagttccttt tagaggaaag cgaaatgaac caggctatac tcgttataca
    14341 gtagaaaaga ttgctgaact tcggaatctt ccgacagaag aagtggctgc ccaaacatgg
    14401 acaaatgcgc accgattatt tggtctaagc gaacatggat aagatgaaga tccaagagat
    14461 tatagtcgtt gaaggaaaag acgatacaag aaggctgcgg gaagtagttg atgcagatac
    14521 gatagaaaca atagggtctg caatcaatga agagatcctg atgcaaattg aacatgccca
    14581 agagactcgt ggagtgatcg tttttaccga tcctgatttt tcaggagaaa aaataagaaa
    14641 aatcattatg gaagctgttc ctcaggcaaa acatgctttt ttgccgcgca cacaagctaa
    14701 accaaagaaa aagggaagcc ttggtgtcga gcatgcaagt gatgctgcta ttttagaagc
    14761 attgaaaaag gtcgtgacgc cagacatttc ccaaacggct gtttctgaaa tcactagaca
    14821 agacctttta gactatggtt taatagctgg ggcacaagca aaagaaaaac gagaaaaact
    14881 aggtgacgag ttgcgcatcg gttacacgaa cggcaaacaa ttggaaaaac gtttgaagat
    14941 gtttcgtatt acgccgaaag aactcgccca agcaatgaaa atagtggagg aacaacatga
    15001 gtgaatatcg tgaaattgcg acaccctcta gaacaaaaga gattttattg aaacatggtt
    15061 tttcatttaa aaaaagttta ggacaaaatt ttctgactga accaaatatt ttaaggaaaa
    15121 tcgtagaaac tgcgcaaata gatgaacata cgaacgtgat cgaagttgga ccaggaatcg
    15181 gtgcattgac ggaacaatta gccaagcatg caaaacaagt cgtagcattt gagatcgatg
    15241 atcgtttgat ccctgtattg gctgatacga tgcaacccta tgacaatgtg actattgtac
    15301 atcaagatat tttaaagacc gatttgtcaa cagctgttag agaaacattt catgaggagc
    15361 ttccgttaaa agtcgtagcg aatttacctt actatattac gacaccgatc atgatgcatt
    15421 ttcttgaatc agatttggtt gtggatgaac tagtcgtcat gatgcaaaaa gaagtagctg
    15481 atcgtatctc tgctgaacca ggaacgaaag cttatggttc attatcgatt gctgttcaat
    15541 attatatgga agccagttta gcattcatcg taccaaaaac agtatttgtc cctcagccaa
    15601 atgtagattc agcgattttg aaactgacaa gaagagatat accggcagtc gaagtgacag
    15661 acgaaaaagc atttttccga ttgacaaaag cggcatttca gcaaagaaga aaaacgcttt
    15721 ggaataactt gcagcattcg tatggcaaag atgaccagac aaaagcatgg ttagcaaaaa
    15781 gcttggaaac agctggaatc gatccaaaac gtcgtgggga gactttgtca ttacaagaat
    15841 tcgccgcatt aagcaatgcg atgtcagaaa atatgcagta aaaaaagagg ttgtgacaga
    15901 agttgtgaaa aagctgtcct gcatcaagta ataagaacag ccaaacaaaa atagttcctc
    15961 atgtttttcg tttgtttggg cttattaccg cagatgcaag cttttgaaca ccgtttaaga
    16021 aagaggttgt gggcctgccg tttaactcta agtcacaagg aacaatttca aaaaacagct
    16081 tctcatgttt ttgagttagt tggtcttatt acttgatgca agcttttgac cactattatg
    16141 ccgaacaagg agatgtgaca caaattttgt cacatctcct atttttgttt cttgatcaaa
    16201 aaattcttat acttgatact cacactcatt ttgtatggat ttagaaaaga atatgtgtct
    16261 tgacagttat tagtaagtga gttatactaa gtcgacattt atgtgtcaag acatattagg
    16321 agagagaaaa aatgagaaaa aattcagttc gaaaactaac gatttctgct ttattgattg
    16381 ggatgggggt cattatccca atggtcatgc ctaaaatcat gattccacca gcttccttta
    16441 ctttggcgtc tcatgtgcca ttatttattg cgatgttttt tacaccagga gttgcagtgg
    16501 ctgttgcgct aggtacgaca tttggtttct ttttaacaac gccggttatc atcgcattgc
    16561 gagcattgtc acatcttgtg tttgcgttga ttggggcttg gtacttgcaa aagcatccga
    16621 gtatcgtttt aaaaaatgga cagtttactt ttgctaattg gcgtttccaa gggttcaatt
    16681 ttgtgatcgg tgtgattcat tctttagcag aaatgctagt agtcagcatc ttttacttta
    16741 ttggtaatat gcctgaaaca tattattctc aaggatattt ttatacagta ttcatcttga
    16801 tggggattgg tgggcttatc cacagtttag ttgattataa tattgcttat tttatagcag
    16861 gaacactcag caaatatttt gatatccccg tatttacggc agcaaaaaaa gaaaatcgga
    16921 aagagtcgat tcaagggtac gcgaagaaaa cgacatatta gacatgatct ctcaaaaaaa
    16981 aaactctcat ctagtaatgg ataataaatc ctctaagatg agagtttttt gtcctaaaaa
    17041 gagctgcacc aacatcttct ggcacagctc taacaggggg caatttatgg aagtttgatg
    17101 acttgttctg tttctttatc aaagaagtgg cctttgctga tgttgaaggc aaggtcgact
    17161 atttcgcctg gtttatggaa atctcttgca tctacttttg agatgaactc agtagaacca
    17221 gtttttgtgt aaagcatcgt ttcagctcca agtaattcgg aaacgacaac ttctgatttc
    17281 actacggctt caggtgaagc ttcaagggct acttgttcac tgtggatgtc ttctggacga
    17341 ataccgaaga taacttcttt tccttcataa cctttttcaa ctaatacttt gttttttcct
    17401 tcaggaatac gaagcttaag cccatgtcca tctgtgataa caccattttt caatgtcaca
    17461 ttaaagaagt tcatggcagg agatccaata aagccggcaa cgaacatatt gacgggtgta
    17521 tcataaactt ctttcggtgt accgatttgt tggataaatc cgtctttcat gataacgatt
    17581 cggtcagcca tagtcattgc ttctgtctga tcgtgagtaa catagatggt cgttgtttca
    17641 agacgctggt gaagtttggc aatctcagca cgcatggcta cacgtaattt agcatctaaa
    17701 tttgataatg gctcatccat taagaagact tttgcatccc gaacgattgc ccgtcccaat
    17761 gccacacgtt ggcgttgtcc accagataaa gcagctggtt ttcgtttcaa gtattctgtc
    17821 agacctaaga tctctgctgc attgtccaca cgttttttga tgtctgcttt atcatattta
    17881 cgtaatttca agccaaaagc catattatca aaaacagtca tatgaggata caatgcgtag
    17941 ttttggaaaa ccatggcaat atcacggtct ttaggtgcca cgtcattcat gacttttccg
    18001 ccgatattta gttctccttc agagatatct tccagtcccg cgatcattcg caaagtagtt
    18061 gactttccac aaccggaagg accaacaaaa acgataaatt cacggtcttt gattgataga
    18121 ttaaaatcag ttacagaata attttctgca ttgtcatatt ttttatatac gtttttcaga
    18181 gccatttcta ccataatacg ttccacactt tcttttttag ttttattaac tatttaaagt
    18241 ataaatgaaa gcgttaacta acttcaatgt catgttgaac aagaattttt tctttttttt
    18301 gtcaatgtgc tagttttaag ctttaataaa tatccataag aaataaaaac tgatacactg
    18361 gagtaaataa gtatgttaac aatatcaaaa ggagtgtctc ttatgaaaat cgctttgatc
    18421 gctcatgacc gaaaaaaacc tatgatggtg aaattagcaa cagcgtataa aacaatattg
    18481 gaaaaacatg aactttttgc taccgggacg actgggcaga ggatcacgga agcaaccggc
    18541 ttgccgatcc atcggtttaa atccggaccg ttaggcgggg atcagcaaat tggagccatg
    18601 atttcggagg atcagttaga tttggtgatt tttcttcgag acccgctggc tgcacagccc
    18661 catgaaccag atgtaacagc acttatccgt ttatctgatg tctatgagat tccgttagct
    18721 acgaatatcg gaacagctga ggtgctacta agaggactgg aagccggctt cctagatttt
    18781 cgaagaatcg tccatgaaat agacaagcat ccactttcat tttgatggat aagcgtatgg
    18841 aaaaataacg tttaatgttc gcctatatgt agctataaaa gctaaacaaa ctgataatat
    18901 gcgatataat acgaacgtat tggataatat aaacaataat attagttttt cgtatttgca
    18961 gtaaatgtga aaatatgcta tagtttctgt gggaaaagat cccaaaaata atacagagta
    19021 gaaaataaag cgttaagtgc taagaggatg ggatgttgcc tcttggacga aggacgtaat
    19081 gttcgcggtt ttattttcgc attcgctgca tgatacgatg tagcagctct taaaggagat
    19141 gctaaaaatg aagaaacacc ggttagacgc acgtatgatt gctattatgg gcttattgat
    19201 tgcattgatg gtcactttgt cccgactggt agcaatcgag accccattta ttaaaatcag
    19261 tgtcacattt attccacaag tgatcatggg cattcttttt ggtccttttt ggtcagggat
    19321 aggcgcagtt ttagctgatt tagtaggaat ggccctcttc tcgaaatctg cattctttat
    19381 tggatttaca ttgaatgcat ttattgaagg agcaatctac ggattctttt tctatcgaaa
    19441 agagatcact tggaaaaatg ccattctggc tacgcttagt gtcacgctga tcatcaactt
    19501 atttttgaca ccattatggc ttgcgttgat gtaccatgtg ccattgttca gctgggtcgt
    19561 ttgggcgccc cgcctgttaa aaacagtaat atggttaccg attcaatcaa ttgccattta
    19621 ttacgtagga cgtagtattc cttacaaaaa aattttaaga agtttagcga tccacgctaa
    19681 ataaaaaaca agcagtcttc ccatcccaga agactgcttg tttttattgt gctgtgaatt
    19741 gtgcttgata gagccgtcgg taataaccat ctttttgaag cagctcatca tgggtgccca
    19801 tttcgacaat agctccctga tccatcacta atatctggtc cgcatttttg attgtggaca
    19861 ggcgatgggc aatcacaaaa ctggtttttc cttccatcat tgctaagaag gcttgttgga
    19921 tttttttctc tgtcaatgta tcgactgagc tggtagcttc atctaagatc aacatagggg
    19981 gattactgat catcgttcga gcaatcgtca acagttggcg ttgtccatct gatatcttta
    20041 acccttgacc gccaatctta gtatctaatt tttccggcaa acgttctaca aattcataca
    20101 tataagaggc ttttagggca tcattgattt ctgcgtcact tgcttccgga ttcccaaaac
    20161 gaagattttc tcgcaatgta ctgtcaaata gccaagtatc ttgtaacacc attccaaaac
    20221 ttttacgtaa tgtatcacgt tggatagagc ggatgtcatg gtcatcgact gtaattgttc
    20281 cttttgttgt gtcataaaaa cgcatcagca aattaacaag tgtggatttt ccggcccctg
    20341 tttttcctac tatagcaatg gtttgacctg gataagcagt aaaattgaaa tcttcgatca
    20401 aacgctgctt ggggtcataa gaaaaagaaa catgatcaaa agagactttt cctttgatat
    20461 ttttgggttc caaggcatag gcatctggca aatcaggctt ttcttctggc tgatcgatca
    20521 aatcaaatgc tcgttctaga ccagaaaaag cggtttgcag ttgtgtcgtg attccagaaa
    20581 gttcgataaa tggtttagaa aactgacttg agtagatcgt aaagctggaa atcacaccaa
    20641 cagtgattga cgaaccactc ttcaatgcca ataggccgcc aactaaacca atcgataaat
    20701 aagcaaggtg atctacaaaa cgagaagacg ggtttgtcaa ggaagaagaa aattgtgccc
    20761 gttgtccttt ttcatataga tcagcattta gcagttcaaa ttgctgttga ctagcttctt
    20821 cttgctgaaa agctttcacg attttctggt taccgattcg ttcggtcaca aagcccgaga
    20881 tatccccaat aatcctttgc tgtctatcga aatttgtttg tgaagcacga gcaacgatcc
    20941 aactcacaag gaaaataatt ggtgtagaac aaagaacgac caatgtcaga agtggactta
    21001 gacgcatcat aaaaataaac gaaagaatga tgattgccac tccagaaaat aattgattga
    21061 aggccgcaga aattgcaatg gaaatattgt ccatatcatt tgtaaatcga ctgacgatat
    21121 ttccgtggga gttttgatca taataacgaa gtggcaatcg attcagatga gcaaatgcat
    21181 cttttcttaa ttttgcaacg gataagtaag ctaaccgatt gcttaacact tggatgagcc
    21241 attgactgac tacgttgatt aaaacgatac caccgaatag aataagtaaa tggaacagtc
    21301 gattgaagcg gacctgtcct tctccaatca tttgatcgat actttgacca atttgtaacg
    21361 tcatcacaac tgttgcaatc ccattgatga ttcctagtat cacagctagc caaatgtctt
    21421 ttgcataggc agtaaggtaa ggaatgaatc ggcggagcgt ctgcaaggat aattttttta
    21481 ctttcataac tattcttcct cctgtgatgc gacgatttcc tgatattctg ctgattgagc
    21541 aagtaattct tcatgggtac cctgagcagc aatcttacct tgatccatca ctaagatatg
    21601 atgtgcttct tgaatagagc ggacacgttg ggagataata atcactgtac tgccaagata
    21661 agtctgtagc gccttacgca aatccaagtc tgtttgataa tccaacgcac ttaaagagtc
    21721 atctaaaatc agtaatgctg gcttggcaat caaagctctt gcaatcgtca gtcgctgttt
    21781 ttgtccgcca gagaaatttt tcccattttc catgactttt gtatctaaac catttggaag
    21841 ctgacggaca aattcttctg cctgagcgat tttcagagct tcccaacatt ctttttctgt
    21901 ggcgtctttc ttaccccatt gaaggttttc acgaatagtc ccggtaaata gtacagaagt
    21961 ttggggaaca agagcaattt gctgacggag atgatccagc tgccaagaac gaacatccat
    22021 tccgtccatt ataactgtac cggaactgac atcatagaaa cgcggaatca attgtgtcaa
    22081 agtcgttttc ccgcttccgg ttggaccaat gattccaagg actgtatttc gcttcagctg
    22141 aaatgtaata ttttggagag aaagaccaga atcaggagta taacggaagt caacatggtc
    22201 aaaagcgata attgcttcag aagaaaaatc gggagtagta ctgacctcag cttcaagaat
    22261 cgaattttct gtgtctagca cctctttcac ccgatttcct gaagcttcgg cacgtgtgaa
    22321 gatcacgacg aggtttgaaa caacgatcag tgccaaaagc atttgattca tataattgat
    22381 caaagcaaga acttgtcctt gttgcaagct accaatattt actttgatcc cgccaactgt
    22441 cagcaaacag atgatcccga cattcatgat caaggttgta gcaggtgata atagggcaga
    22501 gatattggaa acacgtaaat aattgttcgc tagatcattt gtgcttttat cgaacttctc
    22561 tgtttctttt tttgtctgcg caaatgcgcg gatgacacga acaccgctaa gattctgact
    22621 aacgtgttca ttgagctgat ctagtttttc ttgcactttt tggtagagag gaacggtttt
    22681 tttgatgata aaaaataaaa tgattgagaa aataggcaat aatgctaaga aaaacagacc
    22741 tacttcccag tcgatcacaa aagccatgac cactgacccg atacttaaaa acggtgctct
    22801 gatcaataaa cgaatgacca ttgctaaagc tagctgaagc tgattgatgt cgtttgtcat
    22861 tcgggtgatc aaggtatctg ttccaaaatg attcaactcg ttgtgagaga aagtattgat
    22921 ttttttgatt agctgattac gtaactctgt accaaatcct tgtgaagcta ctgaagcata
    22981 gtattggcaa atgatagcac aaatcagacc aatcacagac atagcgacca tccataagcc
    23041 catttcaatg atttttcctc ggtcattcat ttttagtcca ttatcgatca aggaagccat
    23101 cattaaaggc aggacaagtt cgaagacagc ttcaagaaat ttgaagaacg ggcccaaaat
    23161 gatttgctta cgatagtctt ttgcataacg taataactga atcatatgat tcctcctatt
    23221 atttatttgt ccacaattga aaaaacaagt actaccacat tgtagcttag gaaatttaga
    23281 atgaaaagag aacaagcctt ttcataaatg aaagttttat tatgaagaag ctttagaaat
    23341 tgaatagact atttttttta aaaaaaagaa aatgagaaaa catgccagtc tcttcattca
    23401 taggaacgtc tattttactt aatttttcta taaatgaatt ctgcataaaa aatatatcaa
    23461 gtaaatgttt atagatgaaa ctctatttac ttctttttta atttgttctt gcaatctttt
    23521 ttgctacgta atttttgtaa aaaagtgggt tgagagaaat ctaattgatt ttcaaagaag
    23581 gagtatgaaa atgagaaaaa tatttattcg tttattgtgg gtactatctt agaggaataa
    23641 ataatagtgg agaaaactat ggtttggcgc agattctatc aggtttgatg gaacgaagac
    23701 aacctcccga catcaagtca aaagctactt gagattttga tctgaaaata aaaaaagaaa
    23761 acaaggtagg aacatcaatg tttctacctt gttttcgtaa tcaatgggaa aaaactaaga
    23821 gtggtgtacg taatcaataa aaaggatggt gacaacagta cctctttact ctctgaaagc
    23881 atcataactc gtttttcctc attatgccaa taaattgttg ttataccaca tataaggatt
    23941 tgtaatagct aaaaacagac aggaaagttg aaatctgtga atcttatttt gtatggaagg
    24001 atttatagaa cgcaaaaatc aagataaaga tgaataaaaa tcctgtttcg gctatatatt
    24061 gcgtatctac gccaataaaa cgagtttgtt ctgtcatagc catataaagc aaaggcaaaa
    24121 atacaactac agcgagataa gatccgatga tttctcgaaa agttttccag gaagtatgtt
    24181 tcctgttttt atatttatcc gatttcattg aatagtcata gcctccttat tctttcatat
    24241 gttgaaattc cagtataaaa actggaagga actgtacgtt ttttagaata aaaattataa
    24301 gggataagta ggctgctgtc tataataaga tatatttttc aattctttat taaagatttt
    24361 attgacaaaa tgaatccgtt ttctatgatg gaggaggggt gaataagttg ttgaagaagg
    24421 aaattttatg ttacttagag aaccagacag cctttttcga tttagaacat atgaacgagg
    24481 tctttacagc acaaaggtta gctgatcatt ttggggtaaa aagaaacaca gtcagtcatt
    24541 atttgaacca gttaaatgat gagcaactac tagtcaaaat caattctcga ccagtgattt
    24601 atttccacaa agaagctttt gaaaaacaat tttttaagtt acgcacgaat ttttattttt
    24661 ctatcgatga tctcaaagag gaacagcctt ttttcgcgca accaaaagac ttattctctt
    24721 ttatgatcgg atacgacgcc agtttgaaag aaagtatcga acaaatcaaa acagctcttt
    24781 actatccaga tggcggatta ccacttttga ttacaggcga aagtggcaca ggtaaaagtt
    24841 atttagttaa tttggtctat cagtattgtc tgcttcatga tctgctagaa gattctgcac
    24901 cattcatcac ttttaattgt gcacaatatg cagataatcc tgaacttttg actagcaatt
    24961 tgtttggaca tgttaaggga gcgtacactg gtgcagaaga aaataaaaaa ggggcttttg
    25021 aagcagcaga tggtgggatc ttgtttttag acgaggtaca tcgcttaaca ccagaaggtc
    25081 aggaaaaact gttcacctat cttgatcaag gtgtgattta tcgtatggga gaacctaatt
    25141 tgtcacgccg gatcaaaaca cgtctctttt ttgctacgac tgaagagatt actagtcatt
    25201 tcttaacaac tttcattcga agaataccta tccgaatcga actacctgca cttaatcagc
    25261 gtagtcgtaa tgaacggcta gaactgattt actctttttt tctcgaagaa caaagaaaaa
    25321 tggggagccc tttgtcagtc agtggaccag ctttgtcact tttaacaagt cagaaattat
    25381 ccggaaacat aggagagctg aaaaatatcg tcaaagtttc agcagcaaaa gcatatgctg
    25441 aacagcgtga acagcctgaa atccatgtca cgatccatca tttgcaaaaa gaactacttg
    25501 cgcagcctat tactaaaaat acagcacagc aaggaatcta tattacgcaa gaccagacct
    25561 tagagcaatt aatggagaag caacagcccg aacagcagcg aatcgttaaa agttttgagc
    25621 aaatcctaat tgatttcaag aaaaataact gtctgctata ttcttgcgaa ggaaaattaa
    25681 agcaagaagt gattcaatta tttgattttt tgctgtttga gaccagtaga caagaaaaac
    25741 acgagctgct ggtttattgg acacaatcta tccgagagac ctttcgacaa atggaaactg
    25801 cctatcaaat caaattcgat ggaaacagtg tctatgcctt gagttactat ctctatcagc
    25861 gaagcactat caaatggtta ccggaagaac atgatattat ccaactaatc aaagaattag
    25921 aacaacaagt ttctcagtct tatccatcta gttatcacta tgtccaacga attctggaat
    25981 taagtaagat caaattagat attgaagaca caagtatgga tcggatttta ctgacgatct
    26041 atctaaaaaa agcgaaatgg tcaaaagaaa aacgactgcc aaaagcgatg attgctgctc
    26101 acggttatgc aactgctagc agtatggcaa atgtagtaaa tcgtttatta caagaggatc
    26161 tatttgaatc atttgatatg ccactagatg tcacaccaca gcagattgct tcagaaatcc
    26221 ttgattattg cgaaaacagc gatgtttcaa atggattgat catattagta gacatgggat
    26281 ctctgaaaga aatccatcag ttttttaaaa aacagttatc cgtaccgctt ttgattttga
    26341 ataatgtgac gacaccttta gcaatcacag taggggaatg cctgcaaaaa aatgtatcat
    26401 tagaagagat agcagaagag actgttcgac agatccagcc agaatggcga ctgctctatc
    26461 cagaggaaaa caaacccaaa gcactcatta ctacttgctt cactggaatc ggtacggcgg
    26521 tccacttaag tgaactgcta gaaaaaagct tacctacggc ttgtcagttg aaaatcatcc
    26581 catatgaata tcagcaatta aaagataaga aaaacagtga cccattattt tccatatacg
    26641 aagtcgtagg aatgattggc accacagatc ctgatatcac caatatcgac tatctttcat
    26701 tagaagacct catctcgggg gaaaagatgt ctgtactagc tgaatggttg gacactacta
    26761 tgaatgcttc agagaaggaa atattcaatc agcgcatcat tcgtaatttt tcattggaaa
    26821 aagtactgga ttccgtgact attctagata cagagaaggt gatgggagaa atcgatcatt
    26881 ttatgagaga attagaggtg cagttgaatc gaagcatcag caatcccaaa aaattagcgt
    26941 tgtatgtcca tgtgagctgt ctcattgaac gattgatccg acaaatgcca atcgaaacct
    27001 atcaaggatt agagaaatgg aagcagtgtc aaaaagaagg gttatctgct attaaatctg
    27061 cgtttagtgt cattgaagag cattatagtg tcatgatccc caattctgag attgcctata
    27121 tctatgatat tttgagtgaa gatacagagt ttctctcgat agaagaagaa ttttgaacat
    27181 aagcaagttg ttgccactaa ttttggcatg caacttgctt ttttagtatg tgtaagtgaa
    27241 aagaggagat gaaaaagtgg atagagaaat tatcttagct tcccatggaa aatttgcttc
    27301 agggatatta gattcattag agctgatcta tgggaaaaat cattctatta ctgtattcga
    27361 ttgctatact gatgagaatt ttgatttagc ggaaacagta aggcagcttt ttatgaggta
    27421 caaagataaa gaaatcattg ttctgacgga tctttttggc ggaagtgtca acaacgaatt
    27481 cttacaatat atcaatcggg atcatgtcta tctcgttgcc ggattgaatt tgccactatt
    27541 gattgagcta gtatctcggt tggacgctga agtagagaca actgttttga tccagcaggt
    27601 gctaactgat tcaaaaaaaa tgatccagtt ttgtaacgag cggctcaatc agaaaataga
    27661 agaagacgaa ttttaggagg aagaaaaatg attgtattga caagagtcga ccatcggtta
    27721 ttacacggac aagtagcttt ttcatggaca caaacaatag gcgcagactg tattttgatt
    27781 gctaatgatg atgtacctac gaatgagata cgaaagacaa cgatcaaatt agccaagcca
    27841 caaggagtca aactagtgat caaatcaatt gatgactcga ttgccgcgtt gaaaagcggg
    27901 gtgacagata aatataagtt attcatcgta gtggaatcga tcgaggatgc atataagctg
    27961 gcagaagcgt atccagaaat caaaaccatc aacttaggag ggatcaaggc aaaacctggt
    28021 actcgcagca tcggaaaagc ggtaaatatt ttaccagaag aggaggaacg cttgaaacga
    28081 ttaattgaca aacaaataga agtagaaatc cgtcaagtac cagcagataa aaaagtggat
    28141 gtaagagaag ttttgtaaga aaggaagaac ctcaatgatt gtacaagcag tcttattagg
    28201 aattgttgca tttgtcgcac aatcagaata tgcactaggg acatcgttgc tttctcgtcc
    28261 gattgtgacg gggctgttta caggaatcgt gttaggtgat gtaaaaactg ggatcattat
    28321 gggcgcaact ttagagttag catttatcgg atcgttctca gtaggtgctt cgattccacc
    28381 tgatgttgtg accggtggga ttttagggac ggcttttgct attacagctg gagccggtac
    28441 agaaaccgcg cttttactag gtttgccgat tgctacgttg acattgatat tgaaaaatat
    28501 ttacttaggg cttttgattc caattatgaa ccataaagca gacaattatg cagaagaagg
    28561 aaattataaa ggagtcgagc atatgcactt gcttgccggt atcggtcttt ccttgatgct
    28621 tggtgttgtg gtaatggttt cttatatggt gggaagcaat acgatcggaa atctattaaa
    28681 tatgattcct gacttcgttc aaaaggggtt gtcagtagct acagggttga ttccagctct
    28741 tggttttgcg atgcttgctc gtttgctgat caacaaacaa gttgcaccat attttttctt
    28801 aggttttgct atagcttctt acttagagat tcctgtgacc ggagtagcta tttttggtgc
    28861 gattttagca gttgtggtag tcaatattat gaatgtccgt caactaccac ttcaaacaac
    28921 tgcaggggag gtagaagaag atgaagaatt ctgagatcaa aaacagcaaa ataacgaaaa
    28981 aagagctaaa tcacgtattt tggcgttctt ttcaaatgga gttttcttgg aattatgaac
    29041 gtcagatgaa tatggcttat gtttatgcaa tgattccgat tttgaaaaag ttatatcagt
    29101 cgaaagaaga aatggcagca gctttgaaac ggcatctaga gttttttaac acgaccccac
    29161 atatcgttac actgatttta ggaatcacgg ctgcaatgga ggaagaaaat aaggatgatc
    29221 ctgaatttga tgtgactgcg atcgatagta tcaaaacatc tttgatggga cctcttgcag
    29281 ggttaggaga ttctttcttt tggggaactt tgcgattgat tgccacaggt gtgggtacct
    29341 ctttagccat gcaaggaaat attttaggcc ctatcttgtt cattttgatt ttcaatattc
    29401 cgcacattct gtttcgctat ctagcaacag gttggggata tcgcttagga acgggttttt
    29461 tgaaaaagat ccaggcaaac ggtatgatgg aaagtttgac attaggcgcg tctattattg
    29521 gactgatggt cgttggagca atgactgcca cgatgatcac catcaatatt cctttaaaaa
    29581 tcggttcagg agaaaatgct gtgactgttc aaagtatttt tgatgatatc gttccaaata
    29641 tcttatgtct tggagcattt ggcatagtgt tttatctatt gaagaaagaa gtgaaaccat
    29701 taacgatctt gatcggacta gctttctttg gaatttttgg ttcgtggata gggatttttt
    29761 aaaaaaggag cagagaaaat gtttacgatg caagattata tctatgaaga aaaggaagta
    29821 ctaagtacga tcttgaaaaa gaatgatttt tcgacaagag aacatatgaa aaaaacagtg
    29881 aatttactga tcttagcaac gggttcatct tataacgctt gtttagcagc gaagccagca
    29941 ttggaatctt atggtgatct tactgtcgat attcaagaac ctttttattt tttcaattat
    30001 ggaaaacttt ctccttcaat cgatactgtg attgctgtgt cacaaagcgg gaaaagtgct
    30061 tctactgttg aagcagtaaa aatgatacaa aaacaagggt tacctgttgt tgctatcaca
    30121 aatgacgtgc aaagtccact tgctttagaa gctgcacaaa ttattgattt aggtgccggg
    30181 gtagaatcag taggcttcgt tacaaaaggc tattctgcga ctgttttaca gttactactc
    30241 ttagggatag gaattggaat aagtaaaaat aaaatcagca aaaaaataga acaagactac
    30301 atgcaacagt tgcgcaaaat aatcaaccat ttaccagcga ttattcaaaa aacggaagaa
    30361 ttttttgatg gatatcaaag tttatttcgt ttagcacagc gtttcgtcac cattggatat
    30421 ggtccaaact ggggaacagc taaagaagca gagacgaaat tgactgaaac aatccgcgtt
    30481 ccgtcacaag gatttgagtt agaagcttat atgcacggcc catacctgga ggcagatgct
    30541 tcgcatttgc tattctttat tgaaggggaa agtgtaaata aggaacgttc gcaaaagttg
    30601 caaagatata tgagtcggta cgttggagag actctcacca ttaccacaaa aaaagcaaga
    30661 aacgagaaaa cacttggatt agcaatagaa tgtgatgaat atctgtctgt attagcgctt
    30721 gtcgttccgt ttcaactatt cgcttataaa accgcagtag ctaaaggtat tgacttgaac
    30781 aaaaagattt ttgaagactt tgatacagtc ttgaaaagta aattataaga ggtggaaatc
    30841 atgctgaaat tcaatgaaga agaacaaatc aaagcaataa aaggcgcact agctttacgt
    30901 ccgcaagtag aagaaatcat cgataaactt tatgcggaaa aatttgacgc tgtctattat
    30961 ctaggaatcg gtggaacgta tgcttcctcg atgcaagctg tcacttatat gaatgggaaa
    31021 agcaacttgc ctgtctttgt acagcatgct gcagaatatt acactactgg aaacaaaaga
    31081 ttaacaaaag attctatcgt tattttgtcc tctgttaccg gtacaactca agaagtagtg
    31141 aaagcagtag aacaaatcaa gaaagtagga gcgacactga ttggatttat cgataaagcg
    31201 aacagtaagt tgtctcagct atgcgatttt gtggtcactt atccagctcc tggaacagaa
    31261 caaatcaaat tttttatggc agcagatcga ttgatgtatt tgaatggaga attcgaagct
    31321 tattcagaat actatgaaca gctcgaacgt tatttaccaa cagggttagt ggaagcagag
    31381 aaaaaagcag atgcatttgg cttatcattt gcagaaaaac atcgacgtga tagtatgcat
    31441 tattttattg gagcagggaa tcaatgggga gctgtttatt catatgccat gtgttactgg
    31501 gaagaacaaa gctggcttcc atcgaaatct atccatgctg ccgagtttct tcacgggacg
    31561 ttagagatcg tagaagaaac aaccccagtc acattatttt taggcgaaga tgaacagaga
    31621 gtgttatctg aacgtgtggc taaacttttg ccaaaaattt gcagcaatta tacattgata
    31681 gacacaaaag actatccagt agaaggtatc agtgaaaaat atcgcggacg tgttttgtct
    31741 ttcttattga tgcatgtagt gacacaacgc atcgatgctc atgtggagca gttgaactgc
    31801 catccattag agatacgccg ctactatcgt cagtttgatt attaggatag actggataaa
    31861 aagaatataa aaaataaaga gagcagcgat aactgctccc tttatttttt taaaatattg
    31921 gcatcaatta cgttataaaa cacatttttt gcattatcta cagttcaact tataatctgt
    31981 ttaatgggac atgtgggtgc caaccatttt ttgttatgca atagtactat ttagttgttg
    32041 catggatccg tagtaaaagt ccaagtacaa cgagttgcgc cagtttacat agcgttttgt
    32101 atccagaatg ttgactaaaa caaaagttcc tatgtcaacc gtcaacagag acaatctgtc
    32161 cgttgcagga cctgacagat ttagaaatgt tcaatctgtc tcttatgtat tttaaatcaa
    32221 tactcactag gagaagtttc ctaacctcct aatagtaatg ctggtagtaa cattgtcaaa
    32281 actgcttcct cttaggaaca agcaaagcat aacgagtgta aaaataaaat gtagactatt
    32341 gtaacatatc attgattatt tcaagtaaaa acgataaaag aagtaaacaa acacttaaaa
    32401 acaatggaaa ttagtcccaa ctttaagaaa tgtatactat aatggaaatt atcaattatt
    32461 tatttggagg aatatccatg aaacaaaaaa tcgcagttct tggtcctgga tcttggggca
    32521 ctgctttagc acaaacattg gcagaaaacg ggcatgatgt ccgtatttgg ggaaatgtac
    32581 ctgaacagat tgatgaaatc aataagtatc atacaaatca gcatttttta cctgatttga
    32641 cgatcccaga atcgattatc ggatataaag aattggcaga agcagtggat aacgcagatg
    32701 ctattttatt tgttgttcca acaaaagcga ttcgttcagt cgcacaggaa cttattggta
    32761 aaatgaatac taagccaatc attatacatg caagtaaagg actagaacaa gatacgcata
    32821 aacgaatctc agaagttttg gctgaagaaa ttccagaaga aaaaagacag gcaattgttg
    32881 tattatctgg tcctagccat gctgaggaag tggcagtaca tgatatcaca acaattacag
    32941 ctgcaagtat tgatcaaaaa gcagcagcct atgtacaaaa actgttcatg aatgattatt
    33001 tcaggattta tacaaataat gatgtgattg gcgtagaaac tggtgcagca ctgaaaaata
    33061 tcattgcaat tggtgccggc gctatccatg gattaggatt cggagatgat gcaaaagcag
    33121 caatcatgac tcgaggattg gcagaaatca gccgtcttgg tgtcgcgatg ggtgccaatc
    33181 ctctgacatt tatcggtttg agtggtgtgg gggacttgat cgttacttgt acaagtgttc
    33241 attctcgcaa ttggcgtgcc ggtaacttgt taggacaggg acataagctg gaagaagttc
    33301 tagaaaacat gggaatggtc gttgagggtg tggcaacgac aaaagcagca gtagagctag
    33361 ctcaacagct aggtgttgag atgccaatta ctcaaacaat ctataatgtt ttgtataatg
    33421 gagaagatat caaaaaagca gcaaaagaaa tcatgttacg tgacggaaaa atggagaatg
    33481 aattttctct tcgttaaata gatgatcaat agttaatcgt cgtttaggag gaacagcaag
    33541 tgaaggtcaa aaaagcagtc attcctgccg ctgggctagg aacacgtttt ttgccggcaa
    33601 caaaagccat ggcaaaagaa atgcttccaa tcgtggataa accaacgatc cagtttattg
    33661 tggaagaagc attggattcg ggaatcgaag acatcttgat cgtaacggga aaagaaaaaa
    33721 gacccattga agatcacttt gatgcaaata tcgaattgga aaacaatttg cgggaaaagg
    33781 aaaaaacaga attactcgct ttagttgaag aaacgactca agtcaatctt cacttcatcc
    33841 gtcaatctca tccaagagga ctgggggatg ccgtgcttca agcaaaagca tttataggaa
    33901 atgaaccgtt tgtcgtcatg ctgggggatg atttgatgaa agatgatatc ccattgactc
    33961 aacaattgat gatggattat gaagaaacac aagcttccgc tgttgccgtc atgcgtgtac
    34021 cagaaaatga aacatctaaa tacggaatta ttgatcctaa aacagatagc gaaaagggtc
    34081 gttgcagagt aaaagggttt gtagaaaaac ctgaaatggg aaaagcacca agtaatttag
    34141 ccattatcgg acgttatcta ctgactccta aaatatttga gatattagaa actcaagaac
    34201 caggagcagg aaacgagata cagctaacgg atgcacttca gactcttaac cagacagagg
    34261 cggtctatgc gagagagttt aaaggaaaaa gatacgacgt aggcgataag ttaggatata
    34321 tgaagacaaa tattgaatat ggacttcaac attcggaaat tgggacttca ttaagtgcat
    34381 atattatcca gttgagtaaa aagctaagaa cagaaagtta actggaaata agtggcctgc
    34441 tgagaatgaa aggctatttg ttattaaagc ggcagcttgt gcgtcatttg cgcaactgtc
    34501 gttttagttt tttgactcta gatcagttga gtcgtggaaa acgaaagata gaaaaagact
    34561 ttcgtgaata gattcagaaa atattatgct aatggtttaa ttttttttta agttgtataa
    34621 aagaaaatga ttacataaga gaaatgaaag ccaagccaga agattcatag tagaataaaa
    34681 aggcgaattt tttaattata aaaaaaggtg tgtgttcact atgggaaaat tagtcgctgt
    34741 tgcacagtcg ctgcttgata tactcaagtg gctgatggaa ggaagcaatt ggatatttgt
    34801 gttgccacta ttgcttatta gtctatttat catgtttcgc atggtcagaa aaaaagaaac
    34861 gtttctgatt tttatctggt atgcagcatc cgttggggtt gctaccttga tggttgaatt
    34921 ggcgttaggt agttgggaag cttgcgtatt tgctttattt tttgctgtac tgtatctaat
    34981 catttatatc ccatatatga aaagaaagtc tcggataggc agaaaaggta gacatacaac
    35041 tactttttct agtacagatt ctctcgaaca aagtagaaga acgagaagaa gacggtaata
    35101 tttagtaggt atacgcaaaa aaagataaaa taatggataa actattgaga tgagagattt
    35161 atttaattgg tggaaaaaag cttttttcac ttatataaaa gaatcttttt taaaggaatg
    35221 cttgttgtat cgggataagc cattcctttt tttatgttat ttatatatat ataaatcata
    35281 ccaatgtttt tttgtatttt cttgcttgca cttggataag agattactta caataaattc
    35341 agatagaaac agctgaataa aaaaaggctc cctgaccctt agttggcgct aagaatcagg
    35401 gaatgaccag tcacacacat acaccctgac cgatcatttt gccatagtca atgcagtgca
    35461 tcgacctaat ttattgtacc taatctaggg tgaaaattct acccctatgt agatattttc
    35521 catggtctgc acgttgtttt atttgctatg tcaaggtatt gggcgtattc gttcaatgcc
    35581 ttttttgtgt ttgaaacagc aaagaccaca tgtgttactg tctaactact gtttttttat
    35641 gtacttcctt agattaggca gctgtttcta ttcatgtcaa gtatagctag gcgggagaga
    35701 taaatgagtt tatgttattt tgactattat caccaattgg aagagaaatt aaggatagaa
    35761 gagccgctga tgcttcaagc tggcacttgg atcgcgaaac aaattaatca aggtggtaga
    35821 ttgcagatat atgctagccg cacactaagt ggtgtagcat ttgaattttg ggatcaaacc
    35881 ccggatcttg taccaagtat attgattgaa aatccagccg gaggtgtcta tgaaacgcta
    35941 gaaggtgcag gacaggcaat tattgatcag ctttctgtca aatcagaaga catttttctt
    36001 cttctttcga atgaaggaag aaacccggca atcatcgaac tagctcagtg gatcaaagaa
    36061 aatggtcatc cattaatcat tgttactgga tttgatttgt cacgaagtat caaatcgcaa
    36121 catagcagtg gtttgcgatt atttgaattt gctgatttgg ttttggacaa ccacgccaat
    36181 ttacatgatg cagtcttgac tttgccaaat ctagatccag cgatctgcgg aacagcctct
    36241 cttgcaacga tctttttgct gcagcaagtt ttgtatttta cagcaaaaca gctagtccag
    36301 gacacaagtg gaaaatagtt atccacatgt tgacaaagtt ccttaaaaaa ataatgttcc
    36361 acataaaaat ggagcgtttg aaaaaaagaa aacgattatt aatgaggatt aacaacgact
    36421 actttttttg ttttagttat tttaagatgg atcatctttg attttaagct tgttttgttt
    36481 aaagtttgtt atttttataa gttgtttcac agttatgaga aatgagttat aagaatatgt
    36541 agtgtcagaa aaataaaaag tagtggaaaa agagacaaga aagaatccat atggattctt
    36601 tcttgtctct taatacacgt tgatgaaaga gtcttcccca aaactcttta caaagtaatt
    36661 atagtacatt tgttatcatt attgcaatga agtttacctg atataacaaa attgtccaac
    36721 aggatacctt tttctaatag aaataaaata cacaaaaatt gaaggataga taatggatat
    36781 ttataagtgt ttattatttt ttttgcaatg aaattcaatt tttcaa
//
LOCUS       DAZKCH010000020        35300 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000020 DAZKCH010000000
VERSION     DAZKCH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.020"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            135..320
                     /locus_tag="ACG84X_001005"
     CDS             135..320
                     /locus_tag="ACG84X_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9126902.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALIGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            333..581
                     /locus_tag="ACG84X_001006"
     CDS             333..581
                     /locus_tag="ACG84X_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126903.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
     gene            612..782
                     /locus_tag="ACG84X_001007"
     CDS             612..782
                     /locus_tag="ACG84X_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126904.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFIGLDE
                     AEYKTKKPVGRD"
     gene            complement(884..1351)
                     /locus_tag="ACG84X_001008"
     CDS             complement(884..1351)
                     /locus_tag="ACG84X_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126905.1"
                     /translation="MNYLIKILSDYQVAITLIISISGFFLSLYNLFKDKRKITLSYFL
                     VKHDRSNRMILTGVIANPSKMPNSIIECTYLYNGKKINCSHYHANGFDMGSIHKSSLL
                     SPIPLAQAISPGYSVAFSEVLDMKDILPGEKLVMVIRTANYQKKFKLKLKDSF"
     gene            1510..1827
                     /locus_tag="ACG84X_001009"
     CDS             1510..1827
                     /locus_tag="ACG84X_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126906.1"
                     /translation="MLIATDTLDRIFLKDEYKLRNIDASGILVFDLYDNGKIGIYQAS
                     DIEETNLAFEQIDDSVELDLDEAILAFEQIAKLLKEAQKNGNSLPTQRVIYQSPGTGR
                     TIG"
     gene            1760..2239
                     /locus_tag="ACG84X_001010"
     CDS             1760..2239
                     /locus_tag="ACG84X_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HFP9126907.1"
                     /translation="MATLYQLSESYIKVLELAEQLDEEILRDTLDSINEAIEYKAENL
                     AKIVKEVEGKAELIDSEIKRLQERKTSLLNNAKSIKHYLQEEMEKTGKTKIKGELFNI
                     GIQNNPVSVNVINENLIPKGFFTPVPPKLDKKQLKEELKHGDIPGAELVQTKGLRIR"
     gene            2256..2432
                     /locus_tag="ACG84X_001011"
     CDS             2256..2432
                     /locus_tag="ACG84X_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126908.1"
                     /translation="MEHENVKDALKAAIEIAEAKGIKVDGKPATVHDIQNLTKEHLYF
                     IADLLGLSELYLDK"
     gene            2689..3120
                     /locus_tag="ACG84X_001012"
     CDS             2689..3120
                     /locus_tag="ACG84X_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126909.1"
                     /translation="MKNKLAKTTAIIGLALGSGVIGYAASNAFQDLDTIKANFNTVLQ
                     YGQTKSQRVSELESQLSNNTRTQEQLKAEIEQIKSDKQKEIEAKQREVEQKQQEIATK
                     QQEADSLRQQLSTVQNDKEQLEQRVSELRQYTDQKVGELGK"
     gene            3126..3443
                     /locus_tag="ACG84X_001013"
     CDS             3126..3443
                     /locus_tag="ACG84X_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFP9126910.1"
                     /translation="MTIYDPNISWAKHTIKVSFMIWGYKGYVTYKVGGNTKGLSLIAI
                     DSDDLYDANFEDNPVNFRDLDEDWFSMELTNDKGDSTLVEDEFDRLGDYIVGVEIIAH
                     EPE"
     gene            3562..4248
                     /locus_tag="ACG84X_001014"
     CDS             3562..4248
                     /locus_tag="ACG84X_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9126911.1"
                     /translation="MQIKKATDIEQTKGTYLIYGAPGKGKTSTAKYFPGKTLILDIDR
                     TSKVLRGEKNVDIVYIDNEDTWNDWGNTLADLTTNYVGVYDNVVVDNVSELERCILSS
                     LGAEGKNNGVPSQGDYQYMQFRMVNSLRYMKNLDSNLIWTAWEEIDLWTDSDGSSYNI
                     ALPQINRKIRNNILGLCDVVGRLMVKEDDERGFILQATDSTYAKNQLDNRSGCKQSEL
                     ILDGIVRLPE"
     gene            4223..5572
                     /locus_tag="ACG84X_001015"
     CDS             4223..5572
                     /locus_tag="ACG84X_001015"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFP9126912.1"
                     /translation="MELYDYQNDLVDRARQAYVDGYKAPCIVSPCGSGKSVMVAEIAK
                     RTTRKGNRVLFLVHRRELIDQIKDTFQKMGVDNQLVNFGMVQTVVRHLKTIKKPQLII
                     TDENHHGLAASYRKIYEYYSDVPRLGFTATPIRLNGSGLGDVNDLLIEGVSAKWLIEN
                     HRLAPYEYYAPKLIDTAELKKASTGDFTKKSMDKAVKNTIYGDVLKHYKTLAEGEQAI
                     AYCHSIDASKHTAEIFNDAGYKATHIDAKTPKDERADIIEAFRNHEIKILCNVDLIGE
                     GFDVPDCSTVIMLRPTQSLSLYIQQSMRGMRYRPDKTSIIIDHVGNVNRFGLPDMDRE
                     WSLDTKKKTKTDSDLSIVQCAFCFGAYERPKGDNICPYCGELQPIEERKSELEIDESA
                     ELMKVGETKITLNFENNKYYNMTEDEAESIEDLYAIARAKGFKPGWAYMAAKRKGWL"
     gene            5575..6036
                     /locus_tag="ACG84X_001016"
     CDS             5575..6036
                     /locus_tag="ACG84X_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFP9126913.1"
                     /translation="MGGIFGKKAEDVQGSIINGVTIIGDTGKRDSSGNQIVIARNKNN
                     EVFESSLSNIKRGVVNGTGEESGYVNLKKANEKYHVEGTYVKALSVGGTKGVNWDKRR
                     NKWKARLYFKGEYVLQKDFNTKEEAIQARLAAEEKYFKPILEKYENKKEND"
     gene            6038..6538
                     /locus_tag="ACG84X_001017"
     CDS             6038..6538
                     /locus_tag="ACG84X_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010050472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HFP9126914.1"
                     /translation="MTGFNLDFSKAQQGNEIKDGTYEVVVNKAVENATKSGAEFIDID
                     LIVRNDVDQPFQNKHIFAKIWKAKATGKYNEGMIMAIAQALQLEDGKSYNGFDELLAD
                     FVLKTASVRVKTEESNGYKNVNVKSWDKTNTRGVMNHQFKNGDEPSFGPERSRATTVR
                     NDNLPF"
     gene            6553..8865
                     /locus_tag="ACG84X_001018"
     CDS             6553..8865
                     /locus_tag="ACG84X_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage/plasmid primase, P4 family"
                     /protein_id="HFP9126915.1"
                     /translation="MYEKIPKELKNLKQWCVYKLVWDEKRQKHTKIPYNANNGHKAKS
                     NDESTWSDFQTALAAIDHYGMSGLGFFFKPPYFGIDIDNAEGEVERFKSGDIEENIIY
                     EFIESMRSYAEYSQSGTGIHIIARGELPGGRRRKGDVEMYQNGRFFVMTGNAASKYLE
                     ITEPNPKDIKRLYDRYVGDEKIIQFKEENPLMNTVDLPVEEIIKRAESSSQGARFKVF
                     MNGGWEAFYSSQSEADMAFANDLAFWTGRDFEKMDEIFRASAMIRSKYDQKRGSATYG
                     ESLLNKAIADTNSVYNPKRKSDFKIFIKDQEQPKEEKYYSYDDTGNADRFTDIYGTLV
                     KYSYIDKSWYYYDGKVWLQDNTGEVRKMIDTTVDIMGKEPLTIPEGADDETKEALMKA
                     KEKHVKRSRSNAGKNAMMDELKHRLSVLPEEFDKDKTLFNTQSGYLSLHDGLLHEHEI
                     DKMFTRVSNVEYTESVDCPMWEEFINQIFDNDQELIRYIQKCVGYSLTGSTREQCMFI
                     LYGHGSNGKSVFLEIISELMGNYAMTMQAQTIMVKQSQSSANSDIARLKGARLVTSSE
                     PNEGVRLDEGLVKQLTGGDKVTARHLYGKEFEFEPEFKLWLATNHKPIIRGTDDGIWR
                     RLNLIPFTVQIPDHKKDKNLKFKLQTELQGILKWAIDGCLLWQREGLEKPKSVVAASQ
                     DYRNEMDQIGTFIETCCETGPGLKISGGELYKVYREWASDNGEHTFTNTKFGREISKK
                     YSKEKAGGFMVYKGITLKPRKYDNVRELFK"
     gene            9112..9429
                     /locus_tag="ACG84X_001019"
     CDS             9112..9429
                     /locus_tag="ACG84X_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HFP9126916.1"
                     /translation="MKSEHQIQDEIRIALSKHGCTIFRSNAGQVTTIEGRQFYGMPKG
                     FPDLCGHRNSDGKAIYIEVKNERGKLREDQKRFAEFLNGQPVLYGVARSVEEALKIVE
                     ESS"
     gene            9426..9587
                     /locus_tag="ACG84X_001020"
     CDS             9426..9587
                     /locus_tag="ACG84X_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFP9126917.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            9590..9889
                     /locus_tag="ACG84X_001021"
     CDS             9590..9889
                     /locus_tag="ACG84X_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126918.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWSEKTKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKRENVDSKGRQFKHWEKK"
     gene            9889..10203
                     /locus_tag="ACG84X_001022"
     CDS             9889..10203
                     /locus_tag="ACG84X_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFP9126919.1"
                     /translation="MEELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EYGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     DE"
     gene            10196..10726
                     /locus_tag="ACG84X_001023"
     CDS             10196..10726
                     /locus_tag="ACG84X_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFP9126920.1"
                     /translation="MNKKVLIDKQALIDELMKIPGVGSNSDALETIKRFPSYEPQKPV
                     VPKFVAELLDYYRQSTDVDLLALLITFHDWYYRKTKDGEHEEAIDWLVDHPEIYMRAW
                     LFGYELEKEPLYCVIINGRYLVKVFSNTNVVILVPADEFSQYVTQKFQLTEKQIKAID
                     ERYWPFAVPVDEVVEG"
     gene            10723..10992
                     /locus_tag="ACG84X_001024"
     CDS             10723..10992
                     /locus_tag="ACG84X_001024"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126921.1"
                     /translation="MSDPYITKLEKLSEDFEKNKNKLTKDKLIELVRLVIRGAITREK
                     AQQNIEIFARSVRDGLEKKVKQNEQQTPQNNKTKKTGTECTKDKV"
     gene            10922..11125
                     /locus_tag="ACG84X_001025"
     CDS             10922..11125
                     /locus_tag="ACG84X_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HFP9126922.1"
                     /translation="MNNRHRRITKLRKRELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASGAIRKFGISILSDDRKWEEKE"
     gene            11122..11409
                     /locus_tag="ACG84X_001026"
     CDS             11122..11409
                     /locus_tag="ACG84X_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126923.1"
                     /translation="MKLKDGFYSSSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFCGYVEHLYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVI"
     gene            complement(11442..11693)
                     /locus_tag="ACG84X_001027"
     CDS             complement(11442..11693)
                     /locus_tag="ACG84X_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126924.1"
                     /translation="MTMWSMLLFWIPVCIGIVAFCYFVKHSRTNKLLMLSFLPIVFFI
                     VQIVKYTYIESQEIFIFYVVGLFISVVFFIMILSYFYKK"
     gene            11896..12309
                     /locus_tag="ACG84X_001028"
     CDS             11896..12309
                     /locus_tag="ACG84X_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFP9126925.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            12929..13093
                     /locus_tag="ACG84X_001029"
     CDS             12929..13093
                     /locus_tag="ACG84X_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126926.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKENNEV
                     ISFRRRRKAK"
     gene            13090..13320
                     /locus_tag="ACG84X_001030"
     CDS             13090..13320
                     /locus_tag="ACG84X_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126927.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMLREAT
                     PNEVDKCKLIYCGHGYWKDEYIQQNIERWIDR"
     gene            13505..14050
                     /locus_tag="ACG84X_001031"
     CDS             13505..14050
                     /locus_tag="ACG84X_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9126928.1"
                     /translation="MHMHIGEKIYKLRRLNNETMNDLVKQTGVSKSWLSDIESGKKQR
                     VDFNKICAIAKHYKVSLEYFRDDYLDSDEHEDIIPLTGETRVKSVKSLEQSLKYLNNK
                     QEPNLLEIKLKDTDSVPEVWYKGERLDELPKGLVDVSYHWKTDDFTNDDRGANDITIQ
                     YFSSFNDKYPDKKTIGHKRDM"
     gene            14147..14368
                     /locus_tag="ACG84X_001032"
     CDS             14147..14368
                     /locus_tag="ACG84X_001032"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFP9126929.1"
                     /translation="MCQECKRRGRNTRGTIIHHIVEAREDLSLFWSVDNLECICVACH
                     NREHPERSGGKKKPKPKSHIVKMYSTPER"
     gene            complement(14525..14689)
                     /locus_tag="ACG84X_001033"
     CDS             complement(14525..14689)
                     /locus_tag="ACG84X_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HFP9126930.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGQEVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            14791..15312
                     /locus_tag="ACG84X_001034"
     CDS             14791..15312
                     /locus_tag="ACG84X_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFP9126931.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            15299..15739
                     /locus_tag="ACG84X_001035"
                     /pseudo
     CDS             15299..15739
                     /locus_tag="ACG84X_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
     gene            complement(15779..15937)
                     /locus_tag="ACG84X_001036"
     CDS             complement(15779..15937)
                     /locus_tag="ACG84X_001036"
                     /inference="COORDINATES: protein motif:HMM:NF024064.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HFP9126932.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
     gene            16030..16791
                     /locus_tag="ACG84X_001037"
     CDS             16030..16791
                     /locus_tag="ACG84X_001037"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFP9126933.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENFDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            16978..18330
                     /locus_tag="ACG84X_001038"
                     /pseudo
     CDS             16978..18330
                     /locus_tag="ACG84X_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
     gene            18346..19566
                     /locus_tag="ACG84X_001039"
     CDS             18346..19566
                     /locus_tag="ACG84X_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFP9126934.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDVEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALVKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGSNEGLKVKFASNMDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGNNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTTSSKSVAENG"
     gene            19601..20278
                     /locus_tag="ACG84X_001040"
     CDS             19601..20278
                     /locus_tag="ACG84X_001040"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFP9126935.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGINCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAEAPQEETLLQKKLKA
                     LNGGKNE"
     gene            20275..21468
                     /locus_tag="ACG84X_001041"
     CDS             20275..21468
                     /locus_tag="ACG84X_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFP9126936.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRRFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     ITPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSKWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIVNVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTTIANE
                     TPAKV"
     gene            21483..21809
                     /locus_tag="ACG84X_001042"
     CDS             21483..21809
                     /locus_tag="ACG84X_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFP9126937.1"
                     /translation="MILDPKMDLGEIKNALKIDTDDDDVEVSRAAQAAIAYIRGAIGN
                     DKPSFYKQENETVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKASYL
                     LFVEEE"
     gene            21813..22148
                     /locus_tag="ACG84X_001043"
     CDS             21813..22148
                     /locus_tag="ACG84X_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFP9126938.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVPTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            22145..22540
                     /locus_tag="ACG84X_001044"
     CDS             22145..22540
                     /locus_tag="ACG84X_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFP9126939.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEELRQNT
                     PYWDGTKSNGKRGSYMQEHAKNHVVTSSIKNGLVEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            22537..22908
                     /locus_tag="ACG84X_001045"
     CDS             22537..22908
                     /locus_tag="ACG84X_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126940.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EISGNYEDFASNNPLTIQFNVQVDVWVSTMKEVDAFYFALDEVMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            22924..23484
                     /locus_tag="ACG84X_001046"
     CDS             22924..23484
                     /locus_tag="ACG84X_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFP9126941.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGANVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLTKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEGMTLQKFKDLVNNKEGE"
     gene            23609..23920
                     /locus_tag="ACG84X_001047"
     CDS             23609..23920
                     /locus_tag="ACG84X_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126942.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     K"
     gene            23944..24135
                     /locus_tag="ACG84X_001048"
     CDS             23944..24135
                     /locus_tag="ACG84X_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126943.1"
                     /translation="MDQIYKDLIEAGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            24135..27983
                     /locus_tag="ACG84X_001049"
     CDS             24135..27983
                     /locus_tag="ACG84X_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFP9126944.1"
                     /translation="MAGKGQPAGNIKLGISLDSTSFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKEIEDFGDKSTRSARKLDGLKDKLSSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIEKIGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NNVSDVIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGAEPLQEWDVPQYATGTPAGGHPINGPMMVNDGRGA
                     ETVITPDGRAFIPKGRNVVLNAPKGTHVLTAEETAQLQGSKAPKYRYKKGTNFFGNMW
                     DSVKKVAGNVGHTIKNVVGDVWDFISDPGALARKVLGGLDVLGGLTKYPLEVGKGILS
                     KATSALTEKITGLFSSGNLDTSVGTNGVYKYLADVAKSVMKKFPGFVATSGYRPGDPY
                     SHGKRNAIDIALPGVTGGSPRYTEAANYAFDKFASKIGYVITNGKVRDRSGQSGQPAT
                     GAWEPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTA
                     NLNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFD
                     PLSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAK
                     RSRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKG
                     NSRTDRDLALDIQKILVRRM"
     gene            27984..28856
                     /locus_tag="ACG84X_001050"
     CDS             27984..28856
                     /locus_tag="ACG84X_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage distal tail protein domain-containing
                     protein"
                     /protein_id="HFP9126945.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSESVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            28853..29902
                     /locus_tag="ACG84X_001051"
     CDS             28853..29902
                     /locus_tag="ACG84X_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126946.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGVDEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            29906..30730
                     /locus_tag="ACG84X_001052"
     CDS             29906..30730
                     /locus_tag="ACG84X_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126947.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVNSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            30748..32808
                     /locus_tag="ACG84X_001053"
     CDS             30748..32808
                     /locus_tag="ACG84X_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HFP9126948.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDQTNQQIGDLGKLKKMYSNSIDFGGYDYSGNPNL
                     LSKLSYDLIENQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLPSNKTL
                     VMTVKLRAGADYSPVDGKLILIRYRYVDSGTGKIVLDLPINSNSITQEWKEFSITGTT
                     PTFSPQAYHPWIQFRAQDGVLGEIEMSYDIKIEEGSTATPYQPNLLDDSYWLGKTPLG
                     ENLITNAKFPIITRSNPISGFDISEELIIGETYTVSLKGTKPATKEFHLYYGEANYQQ
                     LQYQATLLPVEGLTDVWSATFTARNTSETTNLLRVALWQKPNSATYDTVQIDWLKIEK
                     GDTRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKSLNNTVSLTEPQSIEGLKNF
                     EDGIQSKGKSVLTSDDNKYEVVTLTVTNGNTGSAKLYREGKTVTIYFFALNGKSSGGN
                     DSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAI
                     TYTI"
     gene            32825..32974
                     /locus_tag="ACG84X_001054"
     CDS             32825..32974
                     /locus_tag="ACG84X_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126949.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            32971..33417
                     /locus_tag="ACG84X_001055"
     CDS             32971..33417
                     /locus_tag="ACG84X_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126950.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGVRSDGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYEALEHENGNLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            33419..33556
                     /locus_tag="ACG84X_001056"
     CDS             33419..33556
                     /locus_tag="ACG84X_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFP9126951.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADRIISKEESA
                     S"
     gene            33591..33833
                     /locus_tag="ACG84X_001057"
     CDS             33591..33833
                     /locus_tag="ACG84X_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HFP9126952.1"
                     /translation="MKEEALQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
     gene            33849..34046
                     /locus_tag="ACG84X_001058"
     CDS             33849..34046
                     /locus_tag="ACG84X_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFP9126953.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            34057..35073
                     /locus_tag="ACG84X_001059"
     CDS             34057..35073
                     /locus_tag="ACG84X_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFP9126954.1"
                     /translation="MKKKIILSLSLIMALFLLPINGFAYTINNEFNLGVNEGSSQVAN
                     NQYILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSY
                     ANANSPVQIELQHTHDKVTFEKNYKAYVELARDSANKYGIPLTLDTPYNQPGIKSHLW
                     VTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANP
                     TLSDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYR
                     PDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLN
                     IPKR"
BASE COUNT        12415 a         5876 c         7808 g         9201 t
ORIGIN      
        1 agaaatgtta ttttagaggc tttttataag tcttatttaa ctatgtattc ataatagctt
       61 aaaagctaat aggtgtcaac gatttagcta attttttagc ttacaaatta tttgtttaga
      121 aaggagctat ttttatgtct gagaatttag acttaaaaat tcgagcggag atgagaaaaa
      181 gaagaatgac tttcaaagaa ctagctgcgc ttatcggtat ttcaggagct tatttatcag
      241 atattctaaa cggcaatcgt gatggaaaga aagcacaaca gcatatcgaa acagtgaaaa
      301 aaatattgga catccgatag ggggggtagg cgatgacaaa actaaaaaaa caagattttg
      361 taaaaaaata taattattct ccatctactt atcaacgtcg aatgtcggaa ctaaaaaata
      421 cagcaatttt ctcagcggcg tatgaacggg tcacaggaca agaagtttgg atcaatacag
      481 aattatacga taaatttttg tctttcaaat cctataacag gttacgcaca agaaaggtaa
      541 cacctaaaga atttatcgag aagcatttag ttgatttata aaaaacagaa cattttgaga
      601 ggtgaaggtt aatgggtaaa ttcaacagag cattagtatt cagcgcaccg ctaatcgtct
      661 atgctttagg gctttgggga agtagacaag cgttgatagg aacgattgtg tacatggttt
      721 ggatttttat agggctggat gaagctgagt acaaaacaaa aaagccagtc gggagggact
      781 gactaatgag taaggacgat attgtatttc tgttaattat gttttgtggg attggatcaa
      841 taataattaa tttgtatttg attattaaag aaaaattttt caattaaaat gagtctttta
      901 gctttaactt aaattttttt tgataattag ctgttcttat gaccattaca agtttttcac
      961 caggtaatat atctttcata tctaaaactt ctgaaaaagc gactgagtag ccaggagaga
     1021 ttgcttgtgc caacggtata ggagataaaa ggctactttt atgaatgctt cccatatcaa
     1081 aaccattggc gtgataatgt gaacaattaa ttttcttacc gttgtaaaga tacgtacatt
     1141 cgataattga gtttggcatt tttgatgggt ttgcaattac gccagtaaga atcattcgat
     1201 tacttctatc atgcttaact aaaaaatagg agagcgtaat ttttctttta tctttaaata
     1261 agttatagag ggataaaaaa aatcctgaaa tagaaatgat taaagtaata gcgacttggt
     1321 aatcgctcaa aatttttatc aagtaattca ccaccttttt actcaaatta tatcaaaaag
     1381 gagagaagaa ataatgcaag aattagtaat tttgaaaaat aaaaaaagac acgaacgccg
     1441 gcaagcatga tcgtgtcagg gaaataaact atctttctat attttaccac agaaaggaat
     1501 gaaccgtaaa tgctaattgc aacggataca ctagaccgca tctttttaaa agacgaatac
     1561 aaactgcgca atatagatgc gtcaggaatt ttagtatttg atctttatga caatggaaaa
     1621 attggtatct atcaagcaag tgatattgaa gaaacaaacc ttgctttcga acaaattgat
     1681 gattctgtgg aattggattt agatgaggca atcctagctt ttgaacaaat tgcaaaatta
     1741 ttaaaggagg cacaaaagaa tggcaactct ttaccaactc agcgagtcat atatcaaagt
     1801 cctggaactg gcagaacaat tggatgaaga aattcttcgc gatactctcg attcgattaa
     1861 tgaagcgatc gagtataagg cagaaaactt agcaaaaata gttaaagaag tagaagggaa
     1921 agctgagtta atcgatagtg aaattaaacg tctgcaggaa cgtaagacat cgcttttgaa
     1981 caatgctaag agtatcaagc actatttaca agaggaaatg gaaaagactg gtaaaacgaa
     2041 gattaaaggt gaattattca acattggaat tcaaaataat ccagtatcgg tcaatgtaat
     2101 caatgagaac ttaattccaa aaggattctt tacccctgtg cctcccaaat tggataaaaa
     2161 gcaattgaag gaggaactga agcacggaga tattcctggt gctgaactcg tccaaacaaa
     2221 aggtttgagg ataagatgat gaaggaggag aaataatgga acacgaaaac gtaaaagacg
     2281 ctttgaaagc tgctatcgaa atcgcggaag ctaaaggaat aaaggttgac ggcaaaccag
     2341 caactgtcca tgacattcaa aatttgacga aagaacatct ttattttatc gccgacttgc
     2401 ttggtttgtc ggaattgtat ttagacaaat aaccccacac ggaaggagtg gctagggtgg
     2461 ttgtattaca agtaatagtc tgcgtaacat tcatttggtc gtgcataccg gtttgtatat
     2521 atatcatgaa gaagcttcgc cctgagtctt acaaattata cgcaatttac agcataacag
     2581 tagctcttgc atttacattg tttgcaattt ctaggcttcc gttttaatcg tgggaatgaa
     2641 tttttaatga actaaattat ctataaagca aaaaaaggag aaacaacatt gaaaaacaaa
     2701 ctagcaaaaa caacagcaat catcggacta gcactaggta gcggcgttat cggctacgca
     2761 gcaagcaatg cgtttcaaga tttggacacg atcaaagcaa atttcaacac agtcctacaa
     2821 tacggtcaaa cgaaatcgca acgtgtgtca gaacttgaat cacagctatc caacaacact
     2881 cgcacacagg agcagctgaa agccgaaatt gagcaaatca aatcggacaa gcagaaggaa
     2941 attgaagcca agcaacgaga agtcgaacaa aagcaacagg agatcgctac aaagcaacag
     3001 gaagccgata gcttgcgcca acaactatcc acagtgcaaa acgacaagga gcagttagaa
     3061 cagcgcgtga gcgagttacg gcagtatacg gatcaaaagg taggggagtt ggggaaatga
     3121 aagagttgac tatttatgac ccaaatattt catgggctaa acacacaatt aaagtttctt
     3181 ttatgatttg gggttacaaa ggatatgtta cttacaaagt gggcggtaac actaagggtt
     3241 tatcattaat agctattgat tcagatgatc tatatgatgc taatttcgag gataacccag
     3301 ttaatttccg tgaccttgat gaagattggt tctctatgga acttactaac gataaaggcg
     3361 acagtacact tgtagaagat gaattcgaca gactaggtga ttatattgtc ggtgttgaaa
     3421 ttattgcgca cgaaccagag taggagagtg aatacaaaat gattaaaaga atcactatat
     3481 cagttgaaga agatagtgga tcaacaatgc agcataccga caatcgaaaa acttttttaa
     3541 ccaatagaaa ggagaatttt gatgcagatt aagaaggcga cggatatcga acaaaccaag
     3601 ggaacatatt tgatctacgg tgctccagga aaaggtaaaa cttcaacggc taaatatttt
     3661 ccagggaaaa cactgatcct tgatattgat cggacttcaa aagtccttag aggtgagaaa
     3721 aatgtcgata tcgtatatat cgacaacgaa gatacctgga acgactgggg caacacgttg
     3781 gctgatttaa ctaccaatta tgtaggtgtt tatgacaacg tggttgtcga taatgtcagc
     3841 gaattggaac ggtgtattct gtccagttta ggcgcagaag gaaaaaacaa cggcgttcct
     3901 tcgcaaggcg attatcaata tatgcaattt agaatggtga acagcctacg ctatatgaaa
     3961 aatttagaca gcaaccttat ctggaccgca tgggaagaaa tcgatttgtg gacggattcg
     4021 gatggatctt cttacaacat cgctttgccg cagatcaatc gaaagattcg aaacaatatt
     4081 ttgggattat gtgacgttgt tggtcgattg atggtaaagg aagacgatga acgcggattt
     4141 attttacaag ccacagattc aacctatgcc aaaaatcaat tggataatag atctggctgt
     4201 aagcaaagtg agctgatttt agatggaatt gtacgactac cagaatgatt tagtcgatcg
     4261 tgcaagacaa gcctatgttg atggttacaa ggcaccatgt atcgtatcac cgtgcggttc
     4321 tggaaaatca gtcatggttg cagagatcgc taaacgaacc acacgaaaag gcaacagagt
     4381 gttgttcttg gtccatcgtc gtgaattgat tgatcagatc aaagatacgt ttcaaaagat
     4441 gggcgtagat aatcagcttg taaatttcgg catggttcaa acagtcgtac gacatcttaa
     4501 aaccatcaag aaaccacaac tgatcatcac tgacgaaaac catcacgggt tagcagcgtc
     4561 ctacagaaaa atctatgagt attattcgga cgttccgcga ttaggtttta ccgcgacacc
     4621 catccggtta aacggtagtg ggttggggga tgtgaacgac ttgctaattg aaggagtatc
     4681 ggctaaatgg ttgattgaga atcatagatt agctccttat gaatattatg cacctaaatt
     4741 gatcgataca gccgaattaa agaaagcttc gactggagat tttacaaaga aatcaatgga
     4801 taaggcagtg aagaatacta tttatggcga cgtgttgaaa cattataaaa cgttagcaga
     4861 aggtgaacag gcaatagcat actgtcacag tatcgatgca agtaaacaca ctgctgaaat
     4921 attcaacgat gctggttata aagcaacaca tatcgatgca aaaactccaa aagatgaacg
     4981 tgcagatatt atcgaagcgt tcagaaatca tgaaattaaa atcctatgca atgttgattt
     5041 gatcggagaa gggtttgatg ttcctgattg ttcgactgta attatgttga gacctactca
     5101 atcgttatca ttgtacattc agcaatcgat gagggggatg cgttaccgac cagataaaac
     5161 gtcaatcatc attgaccatg tgggtaatgt gaaccgtttt ggattgcctg atatggatcg
     5221 tgaatggagt ttagatacaa aaaagaaaac aaaaactgat agtgatttat ctatcgttca
     5281 atgcgcgttt tgttttggtg cttacgaacg gccaaaaggc gataatattt gtccgtattg
     5341 cggagagttg cagccgattg aagaacgaaa gtcagagtta gaaatcgatg aatcggctga
     5401 attaatgaaa gtcggagaaa cgaaaattac tttgaatttt gagaacaata aatattacaa
     5461 catgacggaa gatgaagcag aaagtataga ggacttatat gccatagcaa gagctaaagg
     5521 atttaaacct ggttgggctt atatggctgc taagaggaag gggtggttgt aggaatgggc
     5581 ggtatttttg gtaaaaaagc agaagatgtt caaggttcaa taataaatgg cgtaacaata
     5641 ataggtgata ctggaaaaag agatagttca ggcaatcaaa ttgtaatcgc tagaaataaa
     5701 aataacgaag tttttgaatc ttctctatct aatataaaaa gaggtgttgt taacgggaca
     5761 ggcgaagaga gtggctacgt taatttaaaa aaagctaatg aaaaatacca tgttgaagga
     5821 acttacgtta aggctttgtc tgtcggtgga acaaaaggcg ttaattggga taaacgaaga
     5881 aataaatgga aagcacgatt atatttcaaa ggagaatatg tcttacaaaa ggatttcaac
     5941 accaaagaag aagcaatcca agcacgactt gcagcagaag aaaaatattt caaacctatc
     6001 ttagaaaaat atgaaaataa aaaggagaat gattaacatg acaggattta acttagactt
     6061 ttcaaaagcg caacaaggga acgaaatcaa agacggtacg tacgaagtgg tcgtaaacaa
     6121 agctgtagaa aatgcaacta aatcaggcgc agaatttatc gatatcgatt tgatcgttcg
     6181 taacgatgtg gatcaaccgt tccaaaataa acacattttc gcaaaaatct ggaaagccaa
     6241 agctaccggc aaatataacg aaggtatgat catggcaatt gcacaagcgc tacagttgga
     6301 agacggaaaa tcatataacg ggtttgatga attgctggcg gactttgttt tgaaaaccgc
     6361 ctcagtacgc gtgaaaactg aagagtcaaa tggatataaa aacgtcaatg tgaagtcttg
     6421 ggataaaacg aacacacggg gcgtaatgaa tcaccaattc aaaaatggtg atgaaccatc
     6481 cttcggaccg gaacgttcaa gagcgacaac ggttagaaat gacaatcttc cattttaatt
     6541 gaggtgtaat caatgtatga aaaaattcca aaagagctta aaaatctcaa acaatggtgt
     6601 gtttataagc tagtttggga tgaaaagcgg cagaagcaca cgaagatccc ttataacgcc
     6661 aacaacgggc ataaagccaa atccaatgac gagagtacct ggtctgattt tcagaccgct
     6721 ctcgctgcta ttgatcacta cggaatgagt ggactggggt tctttttcaa accaccttat
     6781 ttcggcattg atatcgataa tgctgaaggt gaagttgagc gatttaaatc aggtgatata
     6841 gaagaaaata ttatctatga atttatcgaa agcatgagat cctatgctga gtattctcaa
     6901 tcaggtactg gcatccacat tattgctcgc ggagaattgc ccggcggaag acgcaggaaa
     6961 ggtgacgtag aaatgtacca gaacggccga ttcttcgtta tgactggaaa tgccgcatca
     7021 aaatatttag aaataactga gccgaatcca aaggatatca aacgcctata tgatcgctac
     7081 gttggagatg aaaaaatcat ccaattcaaa gaagaaaatc cgctgatgaa taccgttgat
     7141 ttaccggttg aagaaattat caaacgtgct gaatcgtctt cccaaggggc aagattcaaa
     7201 gtctttatga acggcggttg ggaagctttt tattcctcgc aatccgaagc ggatatggcg
     7261 ttcgccaacg acttggcttt ttggaccggt agagactttg aaaaaatgga tgagattttc
     7321 agagcgtctg caatgatccg tagcaaatat gaccaaaaaa ggggatcggc aacttacgga
     7381 gaatctctac taaataaggc aattgctgat acaaattccg tctacaaccc caaacggaaa
     7441 tctgatttta agatttttat caaagaccag gaacagccaa aagaggaaaa atactattcg
     7501 tacgacgaca ccggcaacgc ggatcggttt actgatatct acggaacgtt agtcaaatat
     7561 tcgtacattg ataaatcttg gtattactac gatgggaaag tttggctaca ggacaatacc
     7621 ggcgaagttc ggaaaatgat cgatacgaca gtagacatca tgggaaaaga accgttaacg
     7681 atccctgaag gcgcagacga tgaaaccaaa gaagctttga tgaaagcgaa agaaaaacac
     7741 gtcaagcgtt ctcgcagcaa tgccggaaaa aacgctatga tggacgaatt gaaacatcga
     7801 ctatccgtat tgccggaaga gttcgacaaa gataaaacgc tgttcaacac acaaagcggc
     7861 tatctgtctt tgcatgacgg tcttctacac gagcatgaga tagacaaaat gtttacacgt
     7921 gtttcaaatg tcgagtacac agaatcggtc gattgtccta tgtgggaaga atttattaat
     7981 cagatttttg acaatgatca agaattaatc agatatatcc agaaatgtgt cggatattcc
     8041 ctgaccggat ctaccagaga gcaatgtatg ttcatcctct acggtcatgg gtcaaatgga
     8101 aagtcggtat ttttggaaat tatttctgaa ttgatgggaa actatgcgat gactatgcag
     8161 gcacaaacga tcatggtcaa gcaaagccaa tcatcagcaa acagtgatat tgcacgattg
     8221 aaaggtgcgc ggttggtcac ttcgtcagaa ccgaatgaag gcgtccgact ggacgaaggt
     8281 ctggtcaaac aattgactgg tggtgataaa gtcacggctc ggcaccttta tggaaaagaa
     8341 ttcgagttcg aacctgaatt caagttgtgg ctggcaacga accacaagcc catcatccgt
     8401 gggaccgatg acggcatctg gcgacggtta aatttaattc cattcactgt ccaaatcccg
     8461 gatcacaaaa aggataaaaa tctgaaattt aaattgcaga cggagttgca agggatcctt
     8521 aaatgggcaa tcgatggttg cctgttgtgg cagagagagg gcttggagaa accaaagtcg
     8581 gttgttgcag cgagtcagga ttatcgaaac gaaatggatc aaataggtac atttatcgaa
     8641 acgtgttgcg aaacaggtcc aggactaaaa atatcaggcg gagaattata caaagtttat
     8701 cgtgaatggg catcagataa tggcgagcat actttcacta acacgaagtt tggcagagag
     8761 atttcaaaga aatatagcaa agaaaaagct ggtggattta tggtttataa aggaatcaca
     8821 ttaaaaccaa gaaaatacga taacgttaga gaacttttta aataaatctg gagggttctg
     8881 gagggttgag aacgaaaccc tccaaccctt agaaacgttg atatatcagt atttatatta
     8941 tatttttctt tctttctgga gggttttaaa aaaataataa agtattaaag taaaaaataa
     9001 aaagtaaatt atataaaaaa gaataggttt ttgggtctga ccctccaaac tctccaccaa
     9061 aatcttccta aatgctttga taccaacgat taaacagtct ggagggttac attgaaatca
     9121 gaacatcaaa tacaagacga gatcagaatt gccttatcaa aacatggttg cacgattttt
     9181 cgatccaatg cgggacaagt gacaacgatc gaagggcggc aattttacgg gatgccaaaa
     9241 gggttcccag atctatgtgg acatcgtaat tctgatggga aagcaattta tatagaagta
     9301 aaaaatgaac gcggtaagtt gcgtgaagat caaaaaaggt ttgctgaatt tttaaacggt
     9361 caacctgtac tatacggtgt tgcacgatca gtggaagaag cattgaaaat tgtggaggaa
     9421 tcatcatgac aacagaagaa gtgattcaaa tgcgtattcg aagccttcag cgtgagattg
     9481 acgatctgga acggacaaag gcagtgatgg tcaatgaaac ggcgaggaag gcaatcgatt
     9541 tgcacataga gaatttaaga agggaaatcc atcgattgga ggaatgagcg tggataagaa
     9601 agcagcaatg aaacgaatca tcgaactgac acattctgag aattggcaag aagacaaaga
     9661 aatagttgca gaagtccaaa agctcggtaa atcaatgtgg agtgaaaaaa ccaaacggag
     9721 aacaccgaga aaaattgcaa tctggcatgg tgaccgaatt ctagtaacag gtactgctga
     9781 acagttatct gaaattactg gattaagcaa aaacattatc tgggatagag ctaaacgcga
     9841 gaacgttgat tcgaaaggtc gtcaatttaa acattgggag aagaaataat ggaggaacta
     9901 atcacaaaag tagagcagtg ggcaaaagat aagggattgg atcaagctga ttccagcaag
     9961 caaatgttaa aaacgatcga agagattggg gaagttgccg cttctctagc tagaaaagat
    10021 gaatatggtt taagagacgg aattggagac gtagtagtaa ccttgattat tttagctatg
    10081 caaaatgata tggatttgta cgagtgtctg aaccaagcat acaacgaaat caaaggacgc
    10141 acaggaaaaa tggtagatgg tgtattcgtg aagtcgagtg atttggagga cagcgatgaa
    10201 taaaaaagta ttaattgata aacaagcatt gattgatgaa ttaatgaaaa tacctggtgt
    10261 gggatctaat agtgacgctt tagaaacgat taaacgtttc ccatcgtatg aaccgcagaa
    10321 gccagttgtg cctaagtttg tggcggaact actcgactat tatcgtcagt caacagatgt
    10381 tgatttatta gctttattga taactttcca tgattggtat tatcgcaaaa ctaaagacgg
    10441 tgagcatgaa gaagcaattg attggctagt tgatcatcct gaaatttata tgcgtgcatg
    10501 gctgtttggc tacgagctcg agaaagagcc gttgtattgc gtaataatca atggtagata
    10561 tcttgtcaaa gtattcagca atacaaacgt tgtcatatta gttccagcag atgaattttc
    10621 acagtacgtt actcaaaaat ttcaattaac tgaaaaacaa atcaaagcaa ttgatgaaag
    10681 atactggccg tttgctgtgc cagtggatga ggtggtagaa ggatgagcga cccatacatt
    10741 actaaattag aaaagttgtc cgaagatttt gagaagaata aaaataaact aactaaagat
    10801 aaacttatag aactggttag gttggttatc agaggagcta ttacaagaga aaaggcgcag
    10861 caaaacatag aaatttttgc tcgtagtgtc cgagatggat tagagaagaa agttaaacaa
    10921 aatgaacaac agacaccgca gaataacaaa actaagaaaa cgggaactga atgtactaaa
    10981 gacaaagttt gaaaaagaat atggaatttc agcagaagaa acatataaag tggcaagtca
    11041 gtgtgttgct gatgcgagcg gcgctattcg taagtttgga atttcgatat taagtgatga
    11101 tcgtaaatgg gaggaaaaag aatgaaacta aaagacggat tttactccag cagtcatggt
    11161 atcggcggtt taatgctaga tatgccgaca aagaacccta aaacacgtga gaaaccaaaa
    11221 ttcaaagtcg gtgacatggt tcgctgtgaa gcagaaggat tcatctatcc attttgtgga
    11281 tatgtagaac atctctataa tcactcagca atcattcgta ttgaaaacac gatggaatgt
    11341 gacaagtggt tagcgaaaag caaagagaat ttagcagtag cgagattggt ggatatggag
    11401 gttatataaa cagcgaaaaa atgtacttct aagagaaaaa tttatttttt ataaaaatag
    11461 gaaagtatca ttatgaaaaa gaccacagag ataaataaac ctaccacata aaaaatgaat
    11521 atttcttgcg attcaatata ggtatattta acaatttgta caataaaaaa tactataggt
    11581 aaaaaagata acatgaggag cttatttgtt ctagagtgtt tgacaaagta acaaaatgcg
    11641 acgataccaa tacaaacggg aatccaaaat aacagcatgc tccacatagt cactcaacca
    11701 tctcctatac gctttattat caatagataa tatcattttt cgtaataaag ataaaaaaat
    11761 aagtaaggct tctcattaaa atataaaaaa gacagccgac cactgactgc ctatataaga
    11821 gtattgaaat aaaaagctgc tgatataata aattccacaa gtttattata tcacataaag
    11881 gagcggtttg acttgatgca attgttacga gaggtagatt tcaaacagac aagatgtaat
    11941 gcgagagatg tgctgaagaa ctttcggcgt ttggagcgga tggcaggtcg ctctttgata
    12001 gatattaagt cgccgattat tacggatatg ccgaaggcgc cgaagcacgg caataaggca
    12061 gaagacgcaa tcattcagat gatggatata gaagcggaga gagacgcgat tctagcagcc
    12121 ttgatggctc ttagtctgat tagtcgtcag atactctact atagcttttg tgtgccagat
    12181 agcttctcaa actacagaat tagccgtgaa gtgggttatt cagaaagaag tatacaacgg
    12241 atgaagtcgg aagctctaat agagtttgca gaagcatata aacacggaag aataattgct
    12301 tataaataat ttggcggctt tttggcggaa tgatggcggt ttttagctat ttaccagtga
    12361 tattatggta gtgtcgaaag attagtgata ggtctaagac aaaataataa taaaaggaac
    12421 atcgttttat tattgtttca caattaagct tcgatagaca gcaacggaaa tattaagaat
    12481 aaggatgtga attttaactc cttctaaatt gttcttatta tctatcatcc gttgctgtct
    12541 attgtttttt taattattca cacgataact aaaggtgagc gaagagaaat gattccatta
    12601 ataatttcaa tttttgcgct ttgtcttaat gtctatatga ttggatttaa aaatgggcaa
    12661 aataaaagat agtagtaact aagaaagaaa tttttatatt gtcactgtgg cggaaagggt
    12721 agacgctaag catgtgtgct aggtcaatgc ttcggcaact atgcaatgtt cgattcattg
    12781 ccagtgactt tggcaaccga ggcatcggcg gtttaaaaat ataggggtgc gcaatttcgt
    12841 acgcgttttg tgcatcgtgt aggttgctat tacatattag atcactcgtt gagtggtctt
    12901 tttattttac ataaaggagg taacaacgat gtatagacca caatacttag aacagaagta
    12961 tgaagtaatc actgtgcaaa acggtaacgg tgagatagta cgaaagtata gaagaccaat
    13021 aaagagcgat acatataaac gaaaggaaaa caatgaagtt atttcttttc gcagaaggag
    13081 aaaagccaaa tgagaaacta ctggtatgta tcgctaacta atgaatatcc tcgaaccatt
    13141 gatgattgtt cagtgcgtgt tgtgcgttct gtacaaatca aagggaagta ctctattgtc
    13201 gaaatgctaa gagaagctac accaaacgaa gtggataaat gcaagctgat atattgcggt
    13261 catggctatt ggaaagacga gtatatccaa caaaacattg agaggtggat agatagatga
    13321 gttacctcga acatttgaaa cgttgctaca tgcattctaa gaataaactt cctgacagct
    13381 acactgtaga tgatgttgct atacatgtat tgaagactga gagccatagc agtcctgatg
    13441 gtagcagtaa ggagcagacg ctcgcgtggt tcaagttctt taagtggatt aaggaggaag
    13501 agtaatgcac atgcacatag gagaaaagat atataaattg agacggctta ataacgaaac
    13561 aatgaacgac ttagttaaac aaactggagt gtcaaaatca tggttatctg atattgagtc
    13621 tggaaaaaag caacgcgttg attttaataa gatatgtgca atagccaaac attataaagt
    13681 tagcttagaa tactttcggg atgattattt ggatagtgat gaacacgagg atattattcc
    13741 tttgacaggc gaaacaagag ttaaatcagt gaaatcgctt gaacaaagcc taaagtatct
    13801 gaataacaaa caagaaccta accttctaga gatcaaacta aaagatactg actcagtacc
    13861 agaggtttgg tacaagggtg agaggttgga tgaattgcct aaaggattag tagatgtctc
    13921 gtatcattgg aagactgatg attttactaa tgatgataga ggagcgaacg acatcacgat
    13981 tcaatacttt tctagcttta atgataagta tccagataag aaaacaatcg gacacaagag
    14041 agatatgtaa atgaaagaag ttagacctag agacgaaata gacaaactat acaagaccaa
    14101 acgatggcga gacctaaggc aagtagtaat agctagggac ttcggcatgt gccaagagtg
    14161 caagcgtcga gggcggaaca caaggggcac gatcatccat cacatagtcg aggcgaggga
    14221 agacctgtca ctgttctggt ccgtagataa ccttgaatgt atctgtgtag cttgtcacaa
    14281 cagagagcat ccagagagat caggcgggaa gaagaaacca aaacctaaat cacatatcgt
    14341 taaaatgtat tcaactcctg aaagataagt ttgcagcgaa atgaaggtag cccccctact
    14401 ctaaaagatt aaagagtaag gcttgagaag aacggtgctg tccttccttc gtaaaaagac
    14461 cgcttttcaa gttttttgga gaaaaaggaa aaagccgacc aatttaagcc ggctttggac
    14521 gaagctattt cttagtccat ttgtttcctt tttgagaagt agggggtaat cggtcgcctg
    14581 gatcaatttt tacttcttgt ccgccttgga catttccacc acgaggaccc acttctttgt
    14641 aggttccttt tggtttgttg tcttcgccgg gtttatagag ttctcccata ggaatccctc
    14701 cttaacaaat ttcggcacag cactgccgat aacctaatta taaggattgt gataacgatt
    14761 tcaatctatc ttttgaaaga aggtgatatt atgccgcaac cagcgaagag tgcaaaatta
    14821 caattattaa acggaaaccc aaataagaag aataccgaag aactccgcaa gcgagcggcc
    14881 gcagaagaca aattaaaaat ggctactgac aaaatcaaac cgccgttatg gctagattcg
    14941 ctaggaaagg atacctttga gtttatcgcc gatgaattgc tgtctgtgga tttaatcagt
    15001 aatccggacg tccatacaat ggctctatac tccaattggt attcgcaata cgtttcttta
    15061 gaaaaacagc ttcgaaaact acaacgagag tacaagttga actatgcgct tgcgaaaaag
    15121 gaggcagagg cgagaggtga gccgtttaat gaacctaatg aattaattgg taatccgctc
    15181 tctcggcaga tggatacagc gtctcggaat ctccgttctt ttggcgctga tttaggacta
    15241 tcaccagcag ccagagctaa gttagctatt aagatggctg atgatggtgg tgatgacgat
    15301 gacgacttct aatattttgg atatgtctta cacagaacgt gtggactatt ggcaaagcta
    15361 tcttgaggag caagcttctt ggggtggctt tttaaaatgt ccatatccgg aattgttaac
    15421 tacttggtat gcggaacgat taatcgatgg aagcatacca gccagcaaag aaaatattca
    15481 agctgctaaa cggcatatgc gtgatttgca gcgccaagga acagatgatt ttccttggat
    15541 ctttgacgaa gaaaaaggtc accggcctat tagatatatc gaaaaaaaat gtaaaccaac
    15601 tgaaggcgac tttggttcgt ttgttttgca accttggcag catttcataa ttggatccat
    15661 gtacggatgg gtacatcgtg atacaggaga gcgtcgcttc cgcgaggctc ttatttttgt
    15721 tggacgtaaa aacggtaagt tttgccgttt aaaaatcggg caaaatcggt gaaaaccttt
    15781 atttttggct ttcttttagt aataattcga tagctttatc aagcaattta gacataggaa
    15841 ccatagtttc ttccgacatt ttttttaatc cttcgtataa atctttatca attgcgttag
    15901 aaattctaat tctgtttttt agtccgtatt tgtccatgtg tgacactcct ttttatttta
    15961 ctataacatc cgattccacc gcttgcaact accatcaatt gatggtagta tataaaagag
    16021 gtgagtagat tgaaaaaata cattatttac aaacacttaa ataaaataaa tggcaaaatt
    16081 tatatcggtg tcacaaatga tattggcaga aggtggagga gcggtgggat tgaatataaa
    16141 ccaccaaaga acgaaaccca acaccacaga agtttttgga atgcaataca aaaatacggg
    16201 tgggaaaatt ttgatcattt gattattgaa gaagacttaa cgatgaaaga agcttttgag
    16261 aaagaaaagt tttatattga actttatgac tcaactaata agaaaaaagg ttataacatc
    16321 gcaaaaggcg gaaatggcgg aataatatat aaagttcacc ccaaaggaat gctagggaaa
    16381 aaacaatcta aagaattttc ttcaaatcac agtaaatggg caaagaacca taagaataat
    16441 tgtatgacaa acggtgatgt tgtatggggt gttactcacg aacacccaaa aggcatgttg
    16501 ggaaagcacc acagcaaaga atcaattatg aaaaagaaag catatagtgg tgaaaatgct
    16561 gtaacctcaa aaccaattgt cgcaattgaa cgggatggaa ctaaaagaga atttcacagc
    16621 gctaagcttt gcatggctta ctattcgatt agtacatgtg ttttttaccg acttttaaaa
    16681 gatggcgccc cttatgtgat aaatcctaaa gcgaactaca gaaataaaga aaaaatatta
    16741 gctatcgaag gaattatgtt caaacataaa gaagataccg aggtaagtta gtagattgcg
    16801 aaaggttact aactaccgta acgcgtagga gttgaataaa tataatgctc ccaagagtgt
    16861 ccgacagcag ataatttgct gaaaatgtac gctaaactgg gccagaactg actgaccgat
    16921 gaaaatgagg gtgacctcca gagtgcgaga taaaaagctc gcagataata acaatcgaaa
    16981 acatcactaa tttcaggcct ttccacatac atggtcgctt atgatgatga acaaggcgcc
    17041 aacgtttacg tattggcaaa tgctcgtgat caagcaagct tgttgtttga taaggccgca
    17101 gaaatggtca aacaatcgcc ggcgctcttt aagaaatttg gtaagcctaa acgatcaagt
    17161 attaattatg ctcccgcctt ttctaaaatg gaaccacgcg cctcagatag ccggaaattg
    17221 gatgggctaa acactcactt tggtattttt gacgagatcc acgagtttac gaattacaat
    17281 ctgatcaacg ttatcaagaa atcaagagga accagaaaac agcctctgat agtttatatc
    17341 acaactgctg gatatgtatt agatggtccg ttgatgtctt attttgagca aggtgtggac
    17401 tgtttggaac atttggaaga tgacatcgat gaacggactt tctattatct ggcaaaactt
    17461 gacagtgcgg aagaggctga tgacccaaga ttatggatca aagccaatcc gaatatttgt
    17521 ctaatgaatt ttgttggcat gctagatgac tatgttaagg ataaaaaaga tccaaaagaa
    17581 tatgctgact ggattaccaa gcaatttaac ttgttttccg atatcgatga gctgtcattt
    17641 gtcgatatgc ctaccattaa acgaaacaat aaaaccatcg atattgaaac gctcaaaggt
    17701 aagaagtgtg tcggtggttt tgacttgtcc gaaacggaag actttaccgc agccgtttta
    17761 gaatttccgc ttgaaacagg cgaggtattc attttgcaac acacatggat cccacaagct
    17821 agatttgatc gagataacaa tcaagagcgt atcaaagcgt gggagaaggt gggagatcta
    17881 acgattattc ctggtgatta cgtcaattat gaatacgtct taaattggtt tgtagaaaat
    17941 tcgaaaatct atgacattgt aaaaatcaat tatgacaagg ccaaggcgct acgattaaat
    18001 aaagaactag aaaatgcagg atttgaaacc aacgagattc ggcaagggtt tctatcatta
    18061 ggtgggccaa tgcaaaactt caaggaaatg ctattggacg gtaaggtgat tttcaacaat
    18121 tccaagcttt accgatggta tctatccaac gtcaagctgg tgatggatcg caactcaaac
    18181 tggatgccgt ctaagcagtc caagagtaga aaaatagatg gttttgcagc aagtttgaac
    18241 agccacgccg aagtgttgaa tatgttggtt aatcctgtcg gaaccgggaa agtaacctat
    18301 tactcgattt ccgatttaat gaatatgtaa gaaaggtgtg gaggaatgag tattttagat
    18361 cgtttgcgtt cttttggccg agcgaagccg aaagcgagca aacaagagta ttttttgaat
    18421 gacccgggat tgataccgta tttagtcgga aaagatgaaa tatcagaagg gattttttcc
    18481 gtaattagcc gtgtatcgaa cgtttttgcg tctctccctc tcaaaatgat agatgtggag
    18541 tttggccaac cggacgactg tcctgcatac aacttgttga gcgaaggccc tcgatatttt
    18601 acaaagtttg attttttccg ggacgtggaa gttttgagaa actaccaagg gaatgcgtat
    18661 gtgcagattt tccgaaatat caatggagaa gtagcagata tggcgttagt aaaacctggt
    18721 gcttgccatc cagtgattga tatggatagc ggggagcttt actaccaagt aactgcgact
    18781 gacaaaggca gttacaagca agttatctat gtacattaca tggaaatgct tcactttaaa
    18841 caaccgaggt ttggcggctt ggaaggtaca gaccccacaa aagtattaac gaataccctc
    18901 ggatatgatc gagaagtccg aaaaatctct ttaagtcagc ttaaaggaag taatgaaggg
    18961 ctaaaagtta agtttgctag caatatggat gaagaagcta aaaaagctac agttaaaaac
    19021 attgctgatt tttatcgaca aaacggtgga ctacttgtgg aagaaaacgg tgtagaaatc
    19081 gaacgtttac aacgagagct ggtagacagc aagcttttag atactgataa agtatctcgc
    19141 tccagaatcg ctatggtcta caatgtgccg gagcatttca tcgggaataa ccagtcgagt
    19201 tactcctctc aggaacagct caatatggaa tttttgacgt acaatctagt accgaccgtt
    19261 aatcaatatg aagcggaact aaataagaaa acactatcga gaaccgaaaa agcaaaaggt
    19321 tatcgatata agtttaatgt cgcaagtttg ctaagagctg acactcaggc aaggggacaa
    19381 ttctatcaaa tcatgcgacg aggcggagca tactcagcga atgatgtccg aagatttgag
    19441 gacttgcaac cgataaataa aaccggtatg gatgattacc atatttccgg agacctatat
    19501 ccaatcgata tggatccaac attaagaaaa acaacctcgt ctaaaagcgt agccgaaaac
    19561 ggttaggttt ttttagtttg caccgaaggg aggtggaaaa atgaaaaaag tgacgttaag
    19621 cggcgatgtc gtggataacg ataccgcgtg gctttatgac tggtttggga tcaattgtat
    19681 ctcaccaggg aaaatttctg ccgctcttac agaagcagcg ggggatgaag tagaacttga
    19741 tatctcatcg aacggtgggg atgtcctagc ggcaagcgaa atatataccg ctatccgtgc
    19801 ctatccggga aaggtatccg gaaatgttgt gagtattgca gcaagcgctg caagtgtaat
    19861 cgcttgcgct tgcgaaccgc ttagaatctc acctacggca cacatcatga ttcataacgc
    19921 atgggtgacc actagtggca acgctgagga attaaaagcc aatgcagaaa tgttaagcag
    19981 tgtggatgag tctattgtta atgcttacga gatcaaaaca ggactcgatc ggaaaaaact
    20041 tgctgattta atggcgaaag atacttggtt aaatgctcaa acagcagtag cagaagggtt
    20101 tgcagatgaa attatgtttg cagaagcacc agtaacggta ctcaatgcct ctcaaccggt
    20161 tattccaaaa aacgcagtaa ctaagttgaa aaatttaata ctcaaagcgg aagcaccgca
    20221 agaagaaaca ctcttacaga aaaaactaaa agccttaaat ggagggaaaa acgaatgaat
    20281 ttagaacaat taaaaaatgc gtgggtcgag gcgggaagta aagtctctga cttaaatgca
    20341 caactcaatg cagcattggt tgacgatgaa aaaacagaag aagatgtagt aagtttgcaa
    20401 gcacaagtaa aagcagcacg ggctaaacgg gacggattga aagagcaagt ggcaaatatg
    20461 gaagccgaac aagtcttaaa cgtcaaaaaa gaaccattag ataaaaaaga tgaaaacttg
    20521 aaaaacaagt ttatcaaaga ctttaaagcg atggtcaatg gtgatcctgc tattatggct
    20581 actttgacat ctaatacgga tgaatctggt aatgctatcg gattgactat tcctgtagat
    20641 gtgcaaacga ctattcatac tttggttcgt cggtttgact ctttgcaaga atacgtaaac
    20701 gttgaaaaag tgaccactac cagcggttct cgcgtttatg aaaaatggtc tgatattaca
    20761 ccgttgactg ctttggatac tgaagacggt gaaatcccag caaatgatga tcctgcactt
    20821 tacttgatca aatacttgat caaacgctat gcaggtattt ccacagtaac taacagcttg
    20881 ctaaaagata ctgccgaaaa cattttggca tggttgtcta aatggatcgc gaaaaaagta
    20941 gttgttactc gcaatacaaa aatcttggca gctattgatg gaatcaaagc ggcacaaaag
    21001 aaagatgtta cagatgttga tggaattaaa gatatcgtaa acgtccaact tgatccagct
    21061 atcgaagcta catctatgtt tattacaaac caagatggct tcaatgtttt agataaagtg
    21121 aaacgtgctg atggatctta cttgttacaa aaagacgtag cttctgcaac tggatatacc
    21181 ttcttaggta aaccaatcaa gaaaattgct tctcgtttct tgccaaacaa aggtacgcaa
    21241 gctactccta aatatccact gtacattggt gatctgaaag aagccgttac attgtatgat
    21301 cgcgaaaaca tgagcttgct gacaacgaat attggtggtg gagcttttga aacagacacc
    21361 actaaagtac gcgtcatcga tcgcttcgat gtgcaactag ttgatgatga agcggttgtt
    21421 ttggctactt ttacaactat tgcgaacgag acaccggcga aagtttaagg agctgattcc
    21481 ttatgattct tgatcctaaa atggatttag gcgaaatcaa aaacgcacta aagattgata
    21541 ccgatgatga cgatgtggaa gtaagccgtg cggcacaagc tgcaattgca tacattagag
    21601 gggctatcgg gaatgataag ccctcttttt ataagcaaga aaatgaaacg gttgatctga
    21661 ttaatttagc tatcctgcaa ttagcagatc attattacaa cgctcgatca gcaaccgtga
    21721 gtgggaactt gcgagagtac gatttaggtt ttacaagcct aatcttgcaa ctcaaagcaa
    21781 gttatttgct ttttgtggag gaggagtagc gtatgcccct tatccaaaca ggaaatttaa
    21841 atcaacgcat caagtttgtc cgagatacga cggttaagga tgaggacggg caagttgtcc
    21901 cgacttctac aaccattctt acttgctggg caagtgtgca gacacaacgc ctgaacgata
    21961 ttaagacgtc gattggtacg gctttggaag gaacactgac gttcattatc cgctaccaac
    22021 aaaaatcaga gctgaccaat gatatgaaag tgcgttggaa tggaaaaacg tttgaaatca
    22081 ttacgattac gaaaggcgag tttgcgaagg acttcacgac aatcattgca aaagaggttt
    22141 caaaatgagt gtagaagtcg atgcaaccga agtgtacaaa gcgcttaggg aagtaaaagc
    22201 aaacgttcaa cgagtggaaa gcccagcact tagaaaagct ggggagtacg ctcaagaaga
    22261 gttacgacaa aacacacctt actgggatgg aacgaagtca aacggtaaac gtggttcgta
    22321 tatgcaagaa catgctaaga accatgtggt tacaagctcg ataaaaaacg gattggtaga
    22381 agtcggctat gacaaagatg tttcttggcg gatgcacttt atcgagttcg gaacaatcaa
    22441 acaacgtcca aaaggtttcg tacaaaaaac acaaaagcaa atcgaaaaac aagtaacaca
    22501 aatcattgct gacgaagtaa aaaggaggct aggactttga aaacggcagt atcacaagtc
    22561 tattcaattc tgaatagcaa tgaaaaaaca aagaacattg atttttacac caatagtgtt
    22621 ccggaatcag ctcaaacagt acctagcctt ccagttggca gaattacaga gatatccggc
    22681 aactatgaag attttgcaag caacaatcct ttgaccattc aatttaacgt acaggtagat
    22741 gtatgggtgt caaccatgaa agaggttgat gccttttatt ttgcccttga tgaggttatg
    22801 agggggaatg gttggcaatg cgcatacacg gaacaaacag atgacgagga cttggaaggt
    22861 gcaaagcgga ttatcaaacg atatgtagca aatatttcac taaattaaaa ggagagaaaa
    22921 tagatggcaa cagtaggatt cgagagcgtc atttttggcg taaaaacagg tgcaggcggc
    22981 actctaaaag aattagtagc agataagtcg aaaggcggag cgatcgaagc taaaattact
    23041 ggattaggcg caacttctaa cacaacatac gcttcaaacg taccgttctt cattgcaagt
    23101 aaaggggttt cgtcgccaaa agttacgctt gacgtggcag acttaatgga taacggcatt
    23161 tacagcgaaa tcattggtgc taaaaccgtg gatggtgcaa atgtaattgg ttcagaaact
    23221 gaagcgcctt acgtgtcggt agtcatggtt acagcgaaca aagaaggaaa acgcttgttc
    23281 atgggattga caaaaggaaa attcagtcat ccagatatcg acatgaaaac agctgaagac
    23341 aaaggggtag aattgcaaac cgattccatc gaaggggaat tcatttctga tgaacgtggc
    23401 tatgtatact taacagccgt agaatcagaa ggaatgacct tacaaaaatt caaggacttg
    23461 gtaaataaca aagaggggga gtagttaacc ctgcatctac accaacgaca gatacaggga
    23521 caccaaaaga accagaacca aaaattgata cacaaggtta gccatttttg gctagcctta
    23581 ttttttgtaa aaacaaggag gaaaacaaat gattgaattg caattgaaac ttgacggaaa
    23641 gaaaaaaaca ttcaaacaac aagatatttc cgcacgtgca atgcgtgagt gtatcaaatt
    23701 ttacgagaaa gcggaaaaag cagacctaac tgatttagaa gcgattgatt caatgattgc
    23761 aattacagca gatattttcc aagatccagc agttacattt gatgctattt tagacggttt
    23821 gactgcgagc gagttagtac cggcattaga aagtgttttt gaacaaataa atgaactggg
    23881 aaacaatgaa aaaaagcaga cggcgagcaa aaagaaataa gtttttctga agctaggaaa
    23941 gcaatggatc aaatctacaa agatttaatc gaagcaggtt ggacgatgag agatgtggac
    24001 gaagccgact atcattattt gttacacctt tttggagaag tggagagtgg cgaagaatat
    24061 gtagatggtg ctgatttcat caaacaattt ttatcggctg aagacttagt aaaacttgag
    24121 gaaggaggta aataatggca ggaaaaggac aaccggcagg aaatatcaag ctagggatta
    24181 gtttagatag cactagtttt ggtaacacgc tggacgaaat caatgcgaaa gtcaaacaag
    24241 ctgagtcgaa tatgcgtgcc aatctaaagg cttatgattc agcaggacgt tcatacgaag
    24301 cacttagtca aaagacgaaa gacttgtcta cggttatgga agggcaaaac gccaaagtaa
    24361 gagaattaac aaagcgccgt gatgaagcga ttagcaagta tggcgaggaa tcgaaacaag
    24421 ttgctaacct taacacacag ataaacaatg ctaccgcaaa atataatgct tacagtcgcc
    24481 agttgaacga cacaaaaaaa gaattggtgt attccaaaac agccgtcaat gatttatcta
    24541 atgaaatcaa agaaaatgaa cgacaaatga acgccgaagt aaaagcgttg aaagccgctg
    24601 gtgatgaatc tggtgctttt gaagcaaaac aaaaagggct agccaaacaa acggaattat
    24661 ccgagaaagc tatcgaagaa cagcgcaaag ttgtgaaact gatggctgat gagtttggcg
    24721 attcagcaaa tgaaaccgaa gatgcaaaaa gggcattaga aaagttagaa cgacaaagcc
    24781 aaatatctag caggcaatta gaagcactca aaagctccag cgatcaatca ggaaaagaaa
    24841 tagaagattt tggcgacaag tccacaaggt cagctaggaa actggacgga ctaaaagaca
    24901 aattaagctc gctaaaaagc gcattttcgt ttggtgcagt tgctggatta gcgcataacg
    24961 ctattagcag tgtagtaagt ggcgtgcaag gtttggttgg cgaagcagta aacgcatcgg
    25021 attcattgat gaagttttcc aaaaccatgg agtttgctaa ctttgggaag tcacagatag
    25081 aaagctcgaa aaaagaaatg aaagactacg ccgataagac ggtttatggt ttagaagaaa
    25141 ttctgaacac aaccgcacaa ttggcatcta atgggattcc taactataca gaactaacca
    25201 aggcggcagg taacttgaat gccgttgcag gcggttctag tgatacattc aaatccgttg
    25261 ccatgatgct aacgcagacg gcaggagctg ggaaactaac aactgaaaac tggaatcaat
    25321 tagcagatgc gataccgggt gcttcaggat tgttacaaga cgctatgttg aaaaacggag
    25381 cttatacagg aaacttccgt gatgcaatgg cgcaaggtca aatcacttcc gacgagttca
    25441 accaagcaat tgtacagtta ggtatgaatg acggagcagt taaggcagcc acttctacag
    25501 acacattgag cggttcttgg gagcagatga aatccactgt aataaatggg ctacaaagta
    25561 ttatagaaaa aataggcgtt gaaaatatca ctggtttcat caacagagta acaaaaggga
    25621 ttgaaaattc tattcctaaa attactcaat ttataggttg gttgagagat attggaacgt
    25681 ggatcgttga aaatagagag ccactaacat ggattgtcgg aatcataggc ggaattacat
    25741 tagcagtaaa agcattgaac gtagcaagta tgttgctggc aattactggc ggaacattgg
    25801 cagccccttt tgtggcgatt ggtgtagcat taggcgcact agcaggtgct ttggtgatag
    25861 cttatacaaa atctgaaaca tttagaaata tagtcaatgc ggcttttaca gctgtgaaaa
    25921 acgtagttat gagcgttatc aataatttgg tggaatacta caaaatgttg tggagcgtgt
    25981 tgcagtggct ttgggaaaaa ataaaagaat gggcttcatg gattggcaat aaattcattg
    26041 aaatgaagaa cagcgttgtg aatacggttc agaacctatg gaatggcgtg aaaaacttct
    26101 tcagcaatgg cgttggagat acgtggaata aggtagtcgg ttgggtaaaa aacattttca
    26161 acaaagcaac tgaattgaag aacaacgttt ctgatgtaat cggtaacctg tggaatggta
    26221 tcaaagacac attccgtaga ggtatcgata cggtattcaa ttggttttca gaactaccaa
    26281 cgaagatgaa gaatgccatt attggcggta aaaacgccat tgttgatgcg ttcaaaagta
    26341 ttttcaacgc agcacttaaa gcgataggta aaccagttaa cgcaatcatc catggagctt
    26401 catgggtact agaaaaattg ggcgcagaac ctctacaaga atgggatgta ccacaatacg
    26461 ctacaggtac accagcaggt gggcacccaa tcaatggtcc aatgatggtt aatgatggac
    26521 gtggagcaga aacagttatc acaccagatg gtagagcctt cattcctaaa ggacgcaatg
    26581 ttgttctaaa cgcaccaaaa ggaacgcatg tcttgacagc agaagagacc gcgcaacttc
    26641 aaggttctaa agctcctaag tatcgttaca aaaaaggtac taacttcttt ggtaacatgt
    26701 gggatagtgt gaaaaaggtt gctggtaatg taggtcacac aattaaaaac gtagtaggtg
    26761 acgtgtggga ctttatttca gacccgggag cgttagctag aaaagtactt ggggggttag
    26821 atgtattagg tggattgaca aagtatccat tagaagtagg taaaggcatc ctatctaaag
    26881 caacaagtgc actgactgaa aaaatcactg ggttgttctc atctggtaac ttagatacct
    26941 ccgtaggaac aaatggcgtc tataaatatt tggctgatgt tgctaagtct gtgatgaaga
    27001 aattcccagg atttgtggca actagtgggt atagaccagg tgacccttat tcacatggta
    27061 aacgtaatgc cattgatatt gcattaccag gcgtcacagg aggctcacct agatacacag
    27121 aagcagcaaa ctacgctttt gacaaattcg cttccaaaat tggttacgta atcactaatg
    27181 ggaaagttcg tgaccgttca ggacaatcag gtcaaccagc aactggtgca tgggagccat
    27241 ggcccgatgg agatcactat gatcatgtgc atttaaacgg tgtgaaagac ccacaaaaca
    27301 ctcaaatttc aggagatagc gtgggaggca gtggggtaga aagatggcgc aatgtagcaa
    27361 ttagagcgtt gaaaatgacc ggtcaataca gtactgcaaa cttaaatgca ttactaaatc
    27421 aaatgcgtac agagtcaaat ggtaatccta atgcagttaa caattgggat attaacgcca
    27481 aaaatggaac accatcaaaa gggttgctcc aagtgattga cccaacattc agacagtatg
    27541 caatgccagg attcaacagc aatatttttg acccactatc taacatctta gcttcaatca
    27601 gatacgcact atcaagatat ggctcactaa caaatgccta tcgtggagtt ggttacgcaa
    27661 acggtggaat tgtaaaccaa catcaaattg cggaaatcgc agaaggaaac aagccagaaa
    27721 ttattattcc gttagataag gctaaacgat caagagcgat gcaattattg tctatcgcaa
    27781 tggacaaact aggagtttct cctaaaactt atggaaatgc gacaactgtt tccagtgatt
    27841 acgaaatcct agaagccatt gaaaaacagg cggcaacaac gaatcagctg ttatcgttat
    27901 tgctggcatt tttcaaagga aatagccgaa ctgatagaga tttagcttta gatattcaga
    27961 agatcttggt taggaggatg tagatgcgaa ctgtattact gagaaataga ataaacgaag
    28021 aaattgattt gtccacagaa gactattttg ctactgggtt gagtaatatg gggtttgaag
    28081 taaaaaaaga acatgtggga cagtggggga atttcagaga aagcagtgag agcgttgaaa
    28141 tatctgaatt tcagtcatct gtaatcattt ctgtgcatgg gtttcgagaa aaagaactgt
    28201 acaattcact tgtgcagttc ctatcggaag gtccgtttga actggaattt gcttttgacg
    28261 gcgaaacaat ggtaagaaga tgcagtctaa aatctttaag taagactgaa atcgatccga
    28321 aaacatcgtt actaacagac actttagaac tatatttcac atcaaactgg tattccgtaa
    28381 aacgcgaaaa attaattcag cgaccgaatg tagtgaaaac acgtggtaag gtttttccgt
    28441 ataaaagatc ttatatctac actcaaaact tgtgggagaa aaaaggtgta ttcaaattca
    28501 ataataattc tgtataccta acgaatagca aggaacggat gtccccgcta aaaattcgtg
    28561 tgattgggaa gtgttcaaat ccgtattggg aagtaatcca aaactcacaa atcatcgcaa
    28621 cggatggata cttcatagat atgactgaaa cacagactct agaagtatca agcctttttg
    28681 aagatacaac ggcgatttta aaagatattg caggggtaga atcttctgtc taccaacaac
    28741 aggattatac aaaaactaat tttgttcagg ccccaactgg agaattcagc attgtgtttc
    28801 atgttggggg ggcagacgta gagattgagt tatacgagga gcgtgatctg ttttgatttt
    28861 agcagtcacg ctttttcatc gtgatttaat gctttataac gaacatttat tctctaacag
    28921 ttttgaattt ggtgtggacg agatcaacga agaggctagt agctttacga tggataagta
    28981 cgttcctgta aaaacaggcg attttctact agcaaaatat attcctagtg gaaaatttgc
    29041 atattttggt gtaattacgt cgcaggaaga cgaaaaaatc agttgtaaaa gcttacttag
    29101 tttagctgat agtgagatac cgactgcacg tgtgtcagga gataactacg aagagcatat
    29161 ccggcggttg attgaatact atttgctgaa tgatccaacg aaacaactaa aagatatttt
    29221 agacgtcaaa gcagaaagtg cgacctctca ttcgtatcaa gctaccgata cgaataaaca
    29281 caagttaagt gcgtatattc tcaatggttt caaaaaatac aacgtaaaat ggtatttcaa
    29341 gggaattcaa aacagaaaaa tttatacagg catacgtgct gtaaatgaat caatttacat
    29401 taaagacaat tcttctgaat ttagcgattg ggatgtgttt gttcaggcgc cgggcgctgg
    29461 aaacgagaac aagctattaa tcgttgataa agcaatgaaa gatatagaga aaccgataat
    29521 actgtcaaca tggtatttgg acgaagaaaa caatttgaca caagatggat cgaaagaaaa
    29581 tatcacgaaa ccaactgtca atttggttaa tatctacgat caaaccgcag aagataaagc
    29641 atcctacgaa gatgtggcaa aatcagagtt gaaaggcaat acgtattcgc atgaaatcaa
    29701 agtgaacgtt gtaagaaatg caaaaaattt gaatgtcgaa acgattgaaa cagggatgtt
    29761 tgccacgatt tcttataaag gaaagatata caagtcggtt ttgacagctt ggcgaatatc
    29821 aagtgataag gagtttgtgg aattgacttt cggaaacata agaagtcgtt ttatggatta
    29881 ttttgaagat aatgggggat aaaaaatggt tagcaatgtg gatggatatc aatttgaaaa
    29941 cgtgaaagta agcgcagaaa atgatgctag actttatcac gttttatata atcggaaaaa
    30001 tcaggttatt gatggttacg atcagtctat gaatttatct tcaagcggat taacagtaaa
    30061 agttgctgca ggagcagcga ttattcaagg tcgtatggtc gttgttcgac aagaagaaag
    30121 tataacagtt ccagcaaact caagtggtta tatagcatta acagtggatt tgacacaaga
    30181 agttatacct ggatctattc ttccagaatc ggaagaatat gaatggacta ataatcaagt
    30241 caagctagaa tttataacaa aagttataaa aggtaattta aacaatggtg ataaggtcta
    30301 taatttacca ctatgctcag ttaattctac tggatcaact gtttcaatct caaagatatc
    30361 ggatagttac gagctgactc tctctaaagg agaaattttg tggaggggga ctgcgttaat
    30421 gcatgatact caaactgtcc aaccttcaaa aaaaatttgg cagacagttt caggtttttt
    30481 gttagtatgg ctcccatacg aaaacgggca agcaattgag gatagatatg taactacgcc
    30541 tttttataag gagcgtgtaa cttttactaa tgttttagga gaaattgttt caggatttga
    30601 tgactatcac aaaaagtggt ttagtaaacg aataaactat aattcgaata ctaatatatt
    30661 tacaggtgca gcaagcaatg caagtggaga taacgcaaat atggtgctta ggtatatagt
    30721 ttctttttag ttaggaggta tggaagagtg gcaaatttag aaattaaatt atctgcaaat
    30781 aagagacagc cttatctacg tcaccgtgtt gttggtagag ttggtgatgg ggggctcaca
    30841 acaatcaatg tacaacttct tgaggaagat gaaattacac cttttgtaat taatctaaac
    30901 ggtactttga aatttgtggg cgaagtttca aacggtaact ataccgaggg agaaccagaa
    30961 ataatcgatt cgactaatgg gttaattagt tacacgttca ctaagtcaaa tttcagcacg
    31021 agtcatcaat tcaaacaagc atattttgaa tatgtagatc ctaacggcaa aaaagtaact
    31081 tttcagaact tcatcataga cgtgttagaa cgagtggata ttaattcgga gcaagcgaaa
    31141 tactatattt cttcattgga aaaattacag agtgaaatgc aaaccacttt caatcagttc
    31201 attagtgata aacaggtcca atacgatcaa atctactcga aatataacga attagtaaga
    31261 ttgataaatg aatcagataa gcaagtaaat gatcgtattg atcaaaccaa tcagcaaatc
    31321 ggcgatctcg gcaagctgaa aaagatgtac agtaacagca tcgactttgg gggctatgat
    31381 tattcgggga atccgaattt gttaagtaag ctatcatacg acttaattga aaatcaaaat
    31441 acttcagctg gaacactttc taagggtgaa aactcgttta aatataataa gatatcagct
    31501 gaagtggaag gtggagtaga gttatattat aaacgaagag gtatagctaa ctggttaccc
    31561 tctaataaaa cgcttgtaat gactgttaag cttagagctg gagcggacta tagtccagtt
    31621 gacggaaaac ttatactgat tagatatagg tatgttgaca gtggaactgg caagattgtt
    31681 ttagacttac ctattaacag taattcgata actcaggaat ggaaagagtt tagtattact
    31741 ggaactactc caacatttag cccacaagca taccatcctt ggatacaatt tagggctcaa
    31801 gatggggtac ttggggaaat agaaatgagc tatgacatca aaatcgaaga aggctctaca
    31861 gctacaccat atcagcctaa cttacttgat gactcttact ggctaggtaa aacaccgttg
    31921 ggtgagaatt tgataacgaa tgccaagttc ccaattataa cacgaagcaa tcctatttct
    31981 ggttttgata tttcagaaga attaataata ggtgaaactt atacggtatc tttaaaaggg
    32041 actaagccag ctactaaaga attccactta tactacggag aagcaaatta ccagcagttg
    32101 cagtatcagg caactttact tcctgtggaa ggattaacag atgtgtggag tgccactttt
    32161 acagccagaa atactagtga aacgacaaat ttacttagag tagcgttatg gcaaaaacct
    32221 aattctgcaa catatgatac tgttcaaatt gactggctca agattgaaaa aggcgacaca
    32281 cgcacaccaa atatcagtca gtttaaatac tttggtgaag gcttgaaaga cagtaacaat
    32341 ccgaacgact acagctggga tgtcacacca gagtatactg aaaaaagctt gaataatacg
    32401 gttagtctga ctgaaccgca atccatcgaa ggattgaaaa atttcgaaga tggtattcaa
    32461 tcaaaaggaa aatctgtatt gacatcagac gacaacaaat atgaagtcgt aaccttaaca
    32521 gttacaaacg ggaataccgg atcagcaaag ctttatcgtg aaggaaaaac cgtcactatt
    32581 tatttttttg cgttgaatgg gaaaagcagt ggtggaaatg attcaacgat actaacaatt
    32641 ccagaaggct atcggccacc aattagtttt gagcaactgg ttggctcgat agaccgttct
    32701 actttgaaca gtgctcagtt atctattggt gcagatggag ccattaaatg gcgaagaaac
    32761 tcaagttatg gatcggatta tacctttgca attacttaca cgatttagaa aggcgtgaat
    32821 cgatatgaag gcagcatata gaccaattga accttacgga ttcgagcaaa tcattgtgaa
    32881 tgatgaagaa catttaccgg aagaatgcac agaagtcgaa ccaccgattc caaattggaa
    32941 accgaaattc aattactggg agggaaataa atgaaaaaca tttggaaata tggccgtact
    33001 ggcggagagt atgcaggaaa agtattggac gacatgcttg tatccgttcc ttacacagat
    33061 cagccaccgc tcgaaggggt tcgttcagat ggcgaaccgc taacgattgc tgatcagatg
    33121 tttgatccta aattgaacca atggattatt ttagcgaacg cgttagatca caacgattta
    33181 aacaatctca aagcgatgta cgaggctctt gaacatgaaa acggcaacct aaaacagcta
    33241 aatgccaaac tcatgctaag cgatgtagcg attaaacagg aaaatactgc attgaaagaa
    33301 aaagctgaca gtttagcaca aatcaattca aaaatgatgc ttgcttcgtt acaaaatagc
    33361 aaagacattt cagaaattaa agagcaacta aatccagctt caaagggagg tgagtagtat
    33421 gtttagtttt agcgatgtga aaatgatgta tgattggggc tgttttactg acgatcaagt
    33481 tcgtctattc gttccactat gtatcacaga tgaagaagca gatagaatta ttagcaaaga
    33541 agagagcgca tcttaagtga tgcgtttttt tgttggaaag ttggtggaac atgaaagaag
    33601 aagcgctcca agacgttgtg gagagattag taagaattga aacaaaatta gacaactacg
    33661 aatcacttag agaaaaagct gatagtgcaa aagatttggc agacaaagcc tactcagtag
    33721 cgctaaacaa cgcagaagat atcaaagaaa tgaaagccaa taataaatgg tcgtggggtt
    33781 acatgatcgg tttaggcatt acgatcattg gctatttctt gactaaattg taaaggagtt
    33841 aagaagaaat gattttaccc gataagtatt atcaagtcat taaatggacg gttttaacag
    33901 tattaccagc tgcatctgtt ttagtagcca cgttaggaaa agcgtatgga tggaatggaa
    33961 cagatatgac agtactcact atcaatgcag tagcaacatt tttaggcgtt atcactggtg
    34021 tgtctgcata taacttaaaa aaataggagg aaaaaaatga agaagaaaat cattttatca
    34081 ttgagcctaa taatggctct ttttttattg ccaattaacg ggttcgccta tacgatcaac
    34141 aatgaattta atttaggtgt aaatgaaggt agctcacaag tagcaaataa ccaatacatc
    34201 ctattgcatg aaacagcaaa cgaaactgcg acaggacgaa atgaagcgca gtacatgaaa
    34261 cgttcttggt acaatgccta tacagcgtat attgttggcg atggtgggat cgtttaccaa
    34321 gttggacaac ctggttatgt acaatatggc gctggttcat atgctaatgc aaatagtcct
    34381 gtgcaaatcg aactgcaaca tacgcacgat aaagtaacgt ttgaaaagaa ctacaaggca
    34441 tatgttgaat tagcgagaga ttccgctaat aaatacggta ttccacttac attagacaca
    34501 ccgtataatc aaccaggaat caaatcacat ttatgggtaa ctcaaaacat ttggggcgat
    34561 cacactgatc cgtatggata cttatcagaa atgggtgtaa gtaaggaaaa actggcttac
    34621 gatttagctc atggatttac agacgaaaac ccaacgactt ctgagaacaa gcctgtcatt
    34681 gatccaaccc gagcaggtgc agcaaatcca actttatcag atggaacgaa ccattctcac
    34741 attgatcagt ttggagaaat cgaaaatgcg aacttacacg tcgctggatg gcacatcgct
    34801 aactataaat acgagtatat tttcattatg gactacaata ctgggaaaga attagctcga
    34861 gtaagagctg atggaattta tagaccggat gtaaatcaag cttataatac ttctggaaac
    34921 gttggctatc atgtatcttt taacatgcgc aatttcccta ataagaaagt atacgtcatg
    34981 atgcgggcaa cgaatgatcc agaaggaaac actaaaggcg gtgcgcaaga tttccatgac
    35041 aaacgttggt atttaaatat tcctaaacga taaaaatagc tcctcgttga ggagcagtac
    35101 atagaattga aaattaacgt taaatcaaaa aaatatttac aagatgttta tttaagtaga
    35161 taataaaaga aaaaagcagg tgaaattgtg acagcagaaa ttggtattat gaataaaagt
    35221 ggaatcgtgt tagcttcaga ttcagcatct acgattggag atagcaaagt atataatact
    35281 gcaaaaaaat tatttacttt
//
LOCUS       DAZKCH010000021        34687 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000021 DAZKCH010000000
VERSION     DAZKCH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.021"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            591..1280
                     /locus_tag="ACG84X_001060"
     CDS             591..1280
                     /locus_tag="ACG84X_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9126955.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="ACG84X_001061"
     CDS             1267..2475
                     /locus_tag="ACG84X_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFP9126956.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="ACG84X_001062"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="ACG84X_001062"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFP9126957.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG84X_001063"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG84X_001063"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFP9126958.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="ACG84X_001064"
     CDS             complement(6578..7273)
                     /locus_tag="ACG84X_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFP9126959.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG84X_001065"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG84X_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFP9126960.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="ACG84X_001066"
     CDS             complement(8472..8663)
                     /locus_tag="ACG84X_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFP9126961.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="ACG84X_001067"
     CDS             complement(8684..9574)
                     /locus_tag="ACG84X_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFP9126962.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="ACG84X_001068"
     CDS             complement(9561..10328)
                     /locus_tag="ACG84X_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFP9126963.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG84X_001069"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG84X_001069"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFP9126964.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG84X_001070"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG84X_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFP9126965.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG84X_001071"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG84X_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFP9126966.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="ACG84X_001072"
     CDS             14899..15282
                     /locus_tag="ACG84X_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126967.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG84X_001073"
     CDS             complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG84X_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFP9126968.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="ACG84X_001074"
     CDS             complement(16226..17044)
                     /locus_tag="ACG84X_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFP9126969.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG84X_001075"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG84X_001075"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFP9126970.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG84X_001076"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG84X_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFP9126971.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="ACG84X_001077"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="ACG84X_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFP9126972.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="ACG84X_001078"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="ACG84X_001078"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFP9126973.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="ACG84X_001079"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="ACG84X_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFP9126974.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="ACG84X_001080"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="ACG84X_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFP9126975.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="ACG84X_001081"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="ACG84X_001081"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFP9126976.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="ACG84X_001082"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="ACG84X_001082"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFP9126977.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /gene="rpsF"
                     /locus_tag="ACG84X_001083"
     CDS             27086..27385
                     /gene="rpsF"
                     /locus_tag="ACG84X_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFP9126978.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="ACG84X_001084"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="ACG84X_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFP9126979.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /gene="rpsR"
                     /locus_tag="ACG84X_001085"
     CDS             27973..28209
                     /gene="rpsR"
                     /locus_tag="ACG84X_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFP9126980.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="ACG84X_001086"
     CDS             28352..30325
                     /locus_tag="ACG84X_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFP9126981.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="ACG84X_001087"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="ACG84X_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFP9126982.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="ACG84X_001088"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="ACG84X_001088"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFP9126983.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="ACG84X_001089"
     CDS             33204..34496
                     /locus_tag="ACG84X_001089"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFP9126984.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10569 a         6743 c         6858 g        10517 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt
    34681 ttccgaa
//
LOCUS       DAZKCH010000022        34518 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000022 DAZKCH010000000
VERSION     DAZKCH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.022"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            212..604
                     /locus_tag="ACG84X_001090"
     CDS             212..604
                     /locus_tag="ACG84X_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFP9126985.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACG84X_001091"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACG84X_001091"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFP9126986.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACG84X_001092"
     CDS             2698..2943
                     /locus_tag="ACG84X_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126987.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3165..4775
                     /locus_tag="ACG84X_001093"
     CDS             3165..4775
                     /locus_tag="ACG84X_001093"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFP9126988.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4752..4964)
                     /locus_tag="ACG84X_001094"
     CDS             complement(4752..4964)
                     /locus_tag="ACG84X_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9126989.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5067..5936
                     /locus_tag="ACG84X_001095"
     CDS             5067..5936
                     /locus_tag="ACG84X_001095"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFP9126990.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="ACG84X_001096"
     CDS             6101..7372
                     /locus_tag="ACG84X_001096"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFP9126991.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="ACG84X_001097"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="ACG84X_001097"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFP9126992.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="ACG84X_001098"
     CDS             8763..9026
                     /locus_tag="ACG84X_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFP9126993.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="ACG84X_001099"
     CDS             9471..9920
                     /locus_tag="ACG84X_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9126994.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="ACG84X_001100"
     CDS             9977..11395
                     /locus_tag="ACG84X_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFP9126995.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="ACG84X_001101"
     CDS             11395..12255
                     /locus_tag="ACG84X_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFP9126996.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="ACG84X_001102"
     CDS             12429..13202
                     /locus_tag="ACG84X_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9126997.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="ACG84X_001103"
     CDS             13349..13714
                     /locus_tag="ACG84X_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFP9126998.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="ACG84X_001104"
     CDS             complement(13862..15070)
                     /locus_tag="ACG84X_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9126999.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="ACG84X_001105"
     CDS             complement(15089..15367)
                     /locus_tag="ACG84X_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127000.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="ACG84X_001106"
     CDS             15560..16216
                     /locus_tag="ACG84X_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFP9127001.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="ACG84X_001107"
     CDS             complement(16658..17455)
                     /locus_tag="ACG84X_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFP9127002.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="ACG84X_001108"
     CDS             complement(17452..18636)
                     /locus_tag="ACG84X_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFP9127003.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="ACG84X_001109"
     CDS             complement(18661..19908)
                     /locus_tag="ACG84X_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFP9127004.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="ACG84X_001110"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="ACG84X_001110"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFP9127005.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="ACG84X_001111"
     CDS             21888..22202
                     /locus_tag="ACG84X_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFP9127006.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="ACG84X_001112"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="ACG84X_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFP9127007.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /gene="tmk"
                     /locus_tag="ACG84X_001113"
     CDS             22887..23531
                     /gene="tmk"
                     /locus_tag="ACG84X_001113"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFP9127008.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="ACG84X_001114"
     CDS             23546..23875
                     /locus_tag="ACG84X_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFP9127009.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="ACG84X_001115"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="ACG84X_001115"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFP9127010.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="ACG84X_001116"
     CDS             24863..25687
                     /locus_tag="ACG84X_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFP9127011.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="ACG84X_001117"
     CDS             25680..26027
                     /locus_tag="ACG84X_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFP9127012.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="ACG84X_001118"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="ACG84X_001118"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFP9127013.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="ACG84X_001119"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="ACG84X_001119"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFP9127014.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACG84X_001120"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACG84X_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFP9127015.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACG84X_001121"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACG84X_001121"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFP9127016.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="ACG84X_001122"
     CDS             31684..32451
                     /locus_tag="ACG84X_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127017.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="ACG84X_001123"
     CDS             32441..34483
                     /locus_tag="ACG84X_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127018.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
BASE COUNT        11100 a         6121 c         7249 g        10048 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaa
//
LOCUS       DAZKCH010000023        33668 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000023 DAZKCH010000000
VERSION     DAZKCH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.023"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(99..1229)
                     /locus_tag="ACG84X_001124"
     CDS             complement(99..1229)
                     /locus_tag="ACG84X_001124"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFP9127019.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACG84X_001125"
     CDS             complement(1878..3080)
                     /locus_tag="ACG84X_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9127020.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACG84X_001126"
     CDS             complement(3140..3343)
                     /locus_tag="ACG84X_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFP9127021.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACG84X_001127"
     CDS             complement(3485..4552)
                     /locus_tag="ACG84X_001127"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFP9127022.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACG84X_001128"
     CDS             complement(4610..4717)
                     /locus_tag="ACG84X_001128"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127023.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACG84X_001129"
     CDS             4880..5692
                     /locus_tag="ACG84X_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127024.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACG84X_001130"
     CDS             complement(6066..6257)
                     /locus_tag="ACG84X_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127025.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
     gene            complement(6502..6732)
                     /locus_tag="ACG84X_001131"
     CDS             complement(6502..6732)
                     /locus_tag="ACG84X_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127026.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVSILIDNKLR"
     gene            complement(6716..6913)
                     /locus_tag="ACG84X_001132"
     CDS             complement(6716..6913)
                     /locus_tag="ACG84X_001132"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFP9127027.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="ACG84X_001133"
     CDS             complement(7059..7937)
                     /locus_tag="ACG84X_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9127028.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="ACG84X_001134"
     CDS             complement(7976..9094)
                     /locus_tag="ACG84X_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFP9127029.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="ACG84X_001135"
     CDS             complement(9091..11190)
                     /locus_tag="ACG84X_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFP9127030.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="ACG84X_001136"
     CDS             complement(11241..12062)
                     /locus_tag="ACG84X_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9127031.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="ACG84X_001137"
     CDS             complement(12059..12868)
                     /locus_tag="ACG84X_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9127032.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="ACG84X_001138"
     CDS             complement(12889..13383)
                     /locus_tag="ACG84X_001138"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9127033.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13895)
                     /locus_tag="ACG84X_001139"
     CDS             complement(13395..13895)
                     /locus_tag="ACG84X_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9127034.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(13960..16656)
                     /locus_tag="ACG84X_001140"
     CDS             complement(13960..16656)
                     /locus_tag="ACG84X_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9127035.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="ACG84X_001141"
     CDS             complement(17084..18157)
                     /locus_tag="ACG84X_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9127036.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="ACG84X_001142"
     CDS             complement(18154..18981)
                     /locus_tag="ACG84X_001142"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127037.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="ACG84X_001143"
     CDS             complement(18982..19788)
                     /locus_tag="ACG84X_001143"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127038.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="ACG84X_001144"
     CDS             complement(19800..20885)
                     /locus_tag="ACG84X_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127039.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="ACG84X_001145"
     CDS             complement(20902..21444)
                     /locus_tag="ACG84X_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFP9127040.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="ACG84X_001146"
     CDS             21702..22691
                     /locus_tag="ACG84X_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFP9127041.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="ACG84X_001147"
     CDS             22688..23425
                     /locus_tag="ACG84X_001147"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFP9127042.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="ACG84X_001148"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="ACG84X_001148"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFP9127043.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="ACG84X_001149"
     CDS             23989..24621
                     /locus_tag="ACG84X_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFP9127044.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="ACG84X_001150"
     CDS             24706..25353
                     /locus_tag="ACG84X_001150"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFP9127045.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="ACG84X_001151"
     CDS             25358..26341
                     /locus_tag="ACG84X_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFP9127046.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="ACG84X_001152"
     CDS             complement(26744..28258)
                     /locus_tag="ACG84X_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFP9127047.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="ACG84X_001153"
     CDS             28396..29202
                     /locus_tag="ACG84X_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127048.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="ACG84X_001154"
     CDS             complement(29377..29946)
                     /locus_tag="ACG84X_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9127049.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="ACG84X_001155"
     CDS             complement(30029..32089)
                     /locus_tag="ACG84X_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFP9127050.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..>33668)
                     /locus_tag="ACG84X_001156"
     CDS             complement(32366..>33668)
                     /locus_tag="ACG84X_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127051.1"
                     /translation="KTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTEI
                     VDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFGV
                     YFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGNQ
                     PIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELDG
                     AFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNWI
                     FDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFLL
                     VGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSDC
                     LLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT        10115 a         7004 c         5695 g        10854 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttaccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttg
//
LOCUS       DAZKCH010000024        32533 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000024 DAZKCH010000000
VERSION     DAZKCH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.024"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..505
                     /locus_tag="ACG84X_001157"
     CDS             131..505
                     /locus_tag="ACG84X_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFP9127052.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACG84X_001158"
     CDS             complement(619..1248)
                     /locus_tag="ACG84X_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9127053.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACG84X_001159"
     tRNA            complement(1382..1454)
                     /locus_tag="ACG84X_001159"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="ACG84X_001160"
     tRNA            1668..1741
                     /locus_tag="ACG84X_001160"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="ACG84X_001161"
     CDS             complement(1879..2043)
                     /locus_tag="ACG84X_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127054.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="ACG84X_001162"
     CDS             2338..3666
                     /locus_tag="ACG84X_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFP9127055.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="ACG84X_001163"
     CDS             3868..4701
                     /locus_tag="ACG84X_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFP9127056.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="ACG84X_001164"
     CDS             4717..5454
                     /locus_tag="ACG84X_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFP9127057.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="ACG84X_001165"
     CDS             complement(5609..6577)
                     /locus_tag="ACG84X_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFP9127058.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="ACG84X_001166"
     CDS             6809..7642
                     /locus_tag="ACG84X_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFP9127059.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="ACG84X_001167"
     CDS             7676..8515
                     /locus_tag="ACG84X_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9127060.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="ACG84X_001168"
     CDS             8541..9101
                     /locus_tag="ACG84X_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9127061.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="ACG84X_001169"
     CDS             9300..11021
                     /locus_tag="ACG84X_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFP9127062.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="ACG84X_001170"
     CDS             11186..12328
                     /locus_tag="ACG84X_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFP9127063.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="ACG84X_001171"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="ACG84X_001171"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFP9127064.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="ACG84X_001172"
     CDS             14128..14775
                     /locus_tag="ACG84X_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFP9127065.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="ACG84X_001173"
     CDS             15168..17813
                     /locus_tag="ACG84X_001173"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFP9127066.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="ACG84X_001174"
     CDS             18123..19436
                     /locus_tag="ACG84X_001174"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFP9127067.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="ACG84X_001175"
     CDS             19426..20079
                     /locus_tag="ACG84X_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9127068.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20826
                     /gene="radC"
                     /locus_tag="ACG84X_001176"
     CDS             20134..20826
                     /gene="radC"
                     /locus_tag="ACG84X_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFP9127069.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20976..21176
                     /locus_tag="ACG84X_001177"
     CDS             20976..21176
                     /locus_tag="ACG84X_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9127070.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21430..23109)
                     /locus_tag="ACG84X_001178"
     CDS             complement(21430..23109)
                     /locus_tag="ACG84X_001178"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFP9127071.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23111..23323)
                     /locus_tag="ACG84X_001179"
     CDS             complement(23111..23323)
                     /locus_tag="ACG84X_001179"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFP9127072.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23716..25446
                     /gene="efrA"
                     /locus_tag="ACG84X_001180"
     CDS             23716..25446
                     /gene="efrA"
                     /locus_tag="ACG84X_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFP9127073.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25443..27203
                     /gene="efrB"
                     /locus_tag="ACG84X_001181"
     CDS             25443..27203
                     /gene="efrB"
                     /locus_tag="ACG84X_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFP9127074.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27298..27495
                     /locus_tag="ACG84X_001182"
     CDS             27298..27495
                     /locus_tag="ACG84X_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127075.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27648..28133
                     /locus_tag="ACG84X_001183"
     CDS             27648..28133
                     /locus_tag="ACG84X_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFP9127076.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="ACG84X_001184"
     CDS             complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="ACG84X_001184"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFP9127077.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29010..29537
                     /locus_tag="ACG84X_001185"
     CDS             29010..29537
                     /locus_tag="ACG84X_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127078.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29628..30365
                     /locus_tag="ACG84X_001186"
     CDS             29628..30365
                     /locus_tag="ACG84X_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFP9127079.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30369..31286
                     /gene="miaA"
                     /locus_tag="ACG84X_001187"
     CDS             30369..31286
                     /gene="miaA"
                     /locus_tag="ACG84X_001187"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFP9127080.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAVDFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31288..32517
                     /gene="hflX"
                     /locus_tag="ACG84X_001188"
     CDS             31288..32517
                     /gene="hflX"
                     /locus_tag="ACG84X_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFP9127081.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5521 c         6874 g         9366 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttattccatc gcagcaggat
    20701 atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac
    20761 cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag
    20821 aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt
    20881 ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt
    20941 taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt
    21001 tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc
    21061 acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt
    21121 tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt
    21181 atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa
    21241 aaatacctgc cacaagagac aatttctctt gtggcaggta tttttttgta tgaaaaagta
    21301 aataaattta agaggctatg aaagagccac cttgtatcaa ggaataagaa caaacaaaaa
    21361 tggcttctca tgtttttcat ttgttttctc ttatattcag gacaaggtgc tgatttcata
    21421 acctcttatt tattcttcat ctggtgtcat taccattggc aaaatcattg gatgtctttc
    21481 tgtacgttcg aataagaaag gctgaagcgc gccagtcatc gcttctttca atttatattc
    21541 tgaacagtca ggtccattca aacattctct taaagcgtgg aataagattc gctgagcttc
    21601 attgatcatt tctcctgatt ctcgcatgta gacaaatcca cgagagagaa tatctggacc
    21661 agccaagatt tcttttttct tgatatccac tgtcgcgaca gctaatacaa gaccttcttc
    21721 tgaaagcagg tgacggtcac gtaaaacgac attaccaata tcaccgatcc cgctaccatc
    21781 gatatacaca tctccagcca caaaatgccc agcaggacgc gcagaatcgc tagttaacgc
    21841 taaaacatcg ccattttcca tgatgaagca gttttctgca ggaacaccta catcttgtgc
    21901 tagagaagca tgtactttca acatgcggaa ttctccgtgg acaggaataa aatattttgg
    21961 cttcatcaaa cgaagcatta atttttgttc ttcttgtcca ccgtgaccgg aagtatggat
    22021 gttattgatt tttccgtgaa tcacttctgc accagcttca gacagcaaat tgatcaaatg
    22081 attgacactt gttgtattac caggaatagg tgaacttgaa aagatcactg tatcgtctgg
    22141 ctggatttgg atttgacggt gagtaccatt cgcgatgcgg ctcaacgcgg ccatcgcttc
    22201 tccttgagaa cctgtacata ggatcatcgt ttcattggca ggcaagcgat tgatttcgtg
    22261 tgcatctaca aatgtgccgt ctggaacttt gatatatcct aaacgttgac cgttgacgat
    22321 ggcattttcc atgcttcgtc cgaaaacagc gattttacga ccagttgcca cagcggcatc
    22381 tgctgcttgc tgcaaacgga agatgttaga agcaaagctg gcaaaaatga tacgtccttc
    22441 gatttttgaa aagatcttca aaatagaatg cccaatcgtt ttttctgatt tagtaaatgt
    22501 tggaatctca gcatttgtac tatcagataa aaggcacaag actccttctt ccccgatacg
    22561 agccatttta tgcaagtttg ctggttcgcc aacaggagtg aaatcgaatt tgaagtctcc
    22621 agtcgctacg atatttccag aaggtgtttt caccacgatc cctaatgcat ctgggatact
    22681 atgggtcgtt ctgaaaaagc tgacagaagt ctttctaaaa cggatgatcg tatcttcatt
    22741 gatctcatgg agctctgcat ctcgaagcaa gccatgctca tctaatttgt ttgtgatcaa
    22801 cgctaatgcg agaggaccag catagatagg aatatttgct tgtttcagca agtagggtat
    22861 tccgccgatg tggtcttcgt gcccgtgagt aatcaccaag gcttttactt tgtgtaagtt
    22921 ttgtatgatg tagctgtagt cgggaatgac atagtcaatt ccaagtaaat cgtcttccgg
    22981 gaatttgatc ccggcatcaa tcaaaatgat ttcatcttgg aattgtaccc catacgtatt
    23041 tttcccgatt tcacctaatc caccaatagc aaagacgcct gtctcgttat ttttgatgga
    23101 aagtttcata ttaaaactcc actaatgaga aatcagcatt ttctttttcg tactctagat
    23161 gacttccttc tagaagttga acgaattcaa tattgtatgg ggtattttct tccacacgtt
    23221 ggcgagcgtc tacatcgctt tttgcctcaa tgtaaagaga ttttgtttct tcccgtttag
    23281 ggttgcgtac ttttgtttct tgataataaa ctttatagat cattgttttg tctcctttat
    23341 ctgcgtaaag cagtgattta gctagttgat ttttttagac aacacaaaac gaggggacaa
    23401 gccacctggt ttttcatatg ctttgactag aatactggat tcgagtcaaa gagacaagcc
    23461 tcgtttttgc ttatctgttc ggatattttt tcaaccgtac cttctgtata aaaaatatac
    23521 aacaattaat tgttattcta gcataaaaca gcaaataagt atagaaatca actagattga
    23581 aagaaaaaat caatgtttat catcccgcta taatcataat gactttttta tgagagaagt
    23641 gttctattaa taggctcgtt gtgctatcat ttttagtaat gaaaatgtaa caaaagatta
    23701 aaaggagatg agaaagtgaa actaatgtgg cattatacca tgcgttataa gaaattcttg
    23761 tttttcaatt tcatatgcgt atttggtttt attttgattg aattaggact tcctacgatt
    23821 ttagcacgta tgatcgatgt aggaatccgc aatgatgatt ttgattatgt gaagcaacaa
    23881 gggatattta tgatcgttat tactgtaatc ggtattattt tgaatatctt gttaggttat
    23941 tttggttcga ggattacgac taatatcgta gcagatattc gagatgattt gttcgaaaag
    24001 atccaaagtt attcgcatca ggaatacgaa aatctaggcg tatcttcatt gatcactcgt
    24061 acaacaaacg atgcttatca gatcatgttg ttcctgcaaa atattttacg tatcggtttt
    24121 atggcaccaa tgatgttcat tgtcagtttg tacatggtca tgcgtacaag tgtgacactc
    24181 agtttgtatg tagtaggtgc attaccttta ctattattgg cagtcgtagc gattgctaag
    24241 gtgtctgaac cgttatctaa aaagcaacaa aaaaacttag ataaaatcaa cagtatcttg
    24301 cgggaaaatc tttcaggatt gcgtgtgatt cgtgcattcg tcaatgaaaa gtttgaagaa
    24361 aaacgttttg ctgtagtcaa tgagaattat gcttctagtt caaaaagctt attccgtttg
    24421 atggctgttg cacaaccggg tttttatttc ttatttaata tcgtaatggt attgatcatc
    24481 tggagcgggg cagtgcaaat cgatgcaggc gagcttcgtg taggagattt gattgcgttt
    24541 atcgagtata tattccatgc cttgttctca ttcatgttat ttgctagtgt gttcatgatg
    24601 tatccaagag cagctgtttc agctggacgt atccaagaag ccctagatgc caaaccttcg
    24661 attgtagaag atccaaatgg tatatctgat acaaaaacta aagggtatat cgaatttcaa
    24721 aatgtaacat ttgcttatcc aggccattcg caagagccag tgatacgaaa tgtcagtttt
    24781 acagcctctc caggagagac cgttgctttt attggaagta ccggtagcgg aaaatctacg
    24841 ttgatccaat tgatccctcg cttttatgat gtgagtgaag gaaagatctt gatcgatgga
    24901 gtagacgtga gagattatcg gctaagcaag ttgcgagata agattgggtt tattccgcaa
    24961 aaagcgctgc tatttactgg aacgattgca gataatttgc gatacgggaa agaagatgct
    25021 acgcaagaag aaatggaacg tgcagctgag attgctcaag cttcagaatt catttctcga
    25081 aaaccagatg gatttaatga acatttatca gaaggtggtt ccaatttttc aggtggacaa
    25141 aaacaacgat tggcaatagc cagagccatc atacgccgtc cggaaatcta tatttttgat
    25201 gacagctttt ctgcattaga ttatcaaacg gatgcgaagt tacgtgctcg tctgaaaaaa
    25261 gaaacgacag aatctactgt attgatcgta gcacaacgtg tgggaacgat catgcatgca
    25321 gataagatca tcgtattaaa tgaaggagaa gtcgtcggta tggggacgca tcgggagttg
    25381 ttggaaaaat gcccgattta ttatgatatt gccgcttctc aattatcaaa ggaggaatta
    25441 gcatgaaaaa aaccttttct tccttaaaac gtttagctcg atatatcaga ccgtatcgtg
    25501 agacttttct tttagtgatc ctatttacag ttctgacagt ggctttcaac gtggctttgc
    25561 catatgttac aggacttcct actacagaaa tcagccgtaa tattgccaat ggcgaatcaa
    25621 tcaatttttc ttatatattc aaatgtctca tttggatcac agttgttgga atagggtatt
    25681 gtatttcgca attactttct ggtgttttga tgacaaatgt cgttcaaagt gccatgcatg
    25741 atttgagaag agacatagaa gaaaaaatca atcgtcttcc ggtttcatat ttcgataaaa
    25801 accagcaagg aaatattttg tctcgtgtga cgaatgatgt agatgcagtc agcggtgctt
    25861 tacaacaagc ttttattggt atcgtaaatg cgatattggg aattacgttg gctgcagcaa
    25921 tgatgtttta tatccagccg atgatggcgc tgatctctat gatcatgatt ccaacatcga
    25981 tctggatctc aaaacgagtg atcaatgctt cgcagaaata ttttcaaagc atgcagaatt
    26041 ctcttggtga gctaaacggc tacgtccaag aaaatatgac aggttttagt gtattgaaag
    26101 tatatggacg cgaaaaagaa acattggaag gattcaaaaa agttaatcac agcttgaaat
    26161 actttgggtt tcgtgcagca ttcatttctg gcttgatgat gcctctagtt caattaactg
    26221 cctatgctac ttatattggt atggctgttc taggaagctt ttatgttatt actggggcga
    26281 tcgttgtcgg tcaactacaa gcattcatcc aatatatttg gcaaatcagt cagccaatgg
    26341 ggaacgtgac acaattgtct tcagttttgc aaagtgcatc agcggcaacg aaacgtgtat
    26401 tcgagatttt agatgagcca gaagaaaaag aaaacaaagt agatgcttca ctgccagaaa
    26461 cgattttagg agatgtgaca ttcgatcatg tcgattttgc atatgatccg aagaaaccat
    26521 taatccaaga tttgaatttt gaagtgaaag ctggtcaaac cgtagctgtg gtcggtccga
    26581 ccggtgccgg caagacgaca ttgatcaatc tattgatgcg tttttatgac gtagacaaag
    26641 gagcaataag gattgatgga atcgacacca aatcaatgag tcgcagtgat gtgcgttcgc
    26701 tatttggtat ggtcttgcaa gatgcatggc tttatcaagg aacgattgca gataatatcc
    26761 gcttcggaaa gcttgatgcg acagattatg aagtagttga tgctgcgaaa acagcaaacg
    26821 tagatcattt tatccgaacg atgccagatg gatatgatat ggccatcaat tctgagggag
    26881 acaatgtgtc tttaggacaa aaacagttgc tgacgattgc ccgagcagtg gtctccgatc
    26941 ctaaaatctt gattttagat gaagcaacaa gttcagtaga cacccgttta gaagcgttga
    27001 ttcaaaaagc aatggatcgc gtgatggagg gacggacaag tttcgtcatc gctcaccgtt
    27061 tatcgacaat ccgtgatgca gatctgattc tagtgatgga tcaaggtcag atcattgaaa
    27121 aaggaacgca tgagagttta ttggcacaag gtggatttta tgaaaaactg tataacagcc
    27181 aatttgctga ggaagcagaa taagtcatat aagaataaaa cagtttaaaa cttatttttt
    27241 gttctctatt cttgataatg gtaaagtaaa gttatcaaga aaagtgagga cacggagatg
    27301 gaacagtttt taaatgaaaa aattactgaa gccaaaagag aagttgatcg tttaacgcac
    27361 gtctgtcaga cgaagccttt tgattcagct gatttttttg aaaatgagtt tcaaatcgaa
    27421 cgcttggcag cacaaataga agtgtacgaa ttaattttaa aaaaagtaat agaagaaaat
    27481 atagatgtac aataaaaaca ggtaaaacgt cagttaccag atactgtaaa tagacatctg
    27541 gcctgagcag gttttacctg ttttttttct tatgaaataa atatatgcta tgataccttt
    27601 attcaatagg attagtttct acaaaaaatg aaaggagaaa aataaatatg gaacggttta
    27661 tagcatcaaa tgccacagtg attggtgatg tgacattgtc agaagatgtg acgatctggt
    27721 atcaagctgt tttacgcggg gacagtaatt ggataaaaat aggacaaaga acgaatatcc
    27781 aagatggtac aatcatccat gtcgatcatg atgcacctgt agatattgcg gagaatgtga
    27841 cggtaggaca tcagtgcatg ctacatggct gtacaatcga aaaaggggcg ctgatcggga
    27901 tggggaccac gatattgaat catgcggtta ttggtgagaa tagtttgatt ggtgctggat
    27961 cattagtaac agaaggaaaa gttattcctc ctaatgtctt ggcttttggt cgcccagcta
    28021 aagtgatccg tcctttgaca aaagaagaaa tacaaaaaaa caaagaaaac atccagcatt
    28081 atgtcgagat aggtcggatg catgcgcaag gaaaattcaa ggagcaaaga taggcagtag
    28141 catccataaa ataaaaaagg atggtcagtt tgagttgacc atcctttttt atttggttta
    28201 gataagagag cttaaaaaag cttcctttga aacagattaa tttaatgaag aactgttttc
    28261 catgacttca tcgatcaatc catatgcttt tgcttgttca gctgtcatat agttgtcacg
    28321 atctgtatct ttttcaatca cttcaagcgg ttgtccagtg cgttcagcta aaattttgtt
    28381 taagcgttcg cgtgtttgca aaatatggcg tgccgcaatt tcgatttcag ttgcttgccc
    28441 ttgagcgccg ccaagaggtt gatggatcat gatctcagca tttggtaaag caaatcgttt
    28501 accttttgta ccagctgtca gcaagaagct tcccattgaa gcagccatac ccataacaat
    28561 tgtttggaca tctgctttga caaagttcat tgtgtcgtaa atagccatac ctgctgtaac
    28621 tgaaccacca ggagaattga tataaagata gatatctttt tcagaatctt gagcgtctaa
    28681 gaaaagcaat tgggcgatga tcgaattagc aagatcatct gttacttggc cgcttaacat
    28741 gatgatacgg tctttcaata aacgtgagta gatatcgtaa gctctttcac ctcgtgaaga
    28801 ttgttcaatg actgtaggaa ttaaattcat aatagagttc ctccttgatt tcgtttagaa
    28861 atagtgtacc ataatttagt ttctaatacc taaaatgtag tatacatttt tggtcaaaaa
    28921 aggtcaaata aaaaacttag gcaaattagt cgcataaacc cgctttatgg tatgataagc
    28981 agagaaacaa aacaaggagg aacaacagat tgatagttgg tattactggc cttatcggag
    29041 tgctgacagg tgctgtagtt gtctatatcg gcatgatact gcaaatgcgt cacttggaaa
    29101 ataaagaaca gcgtagacgt gaattggaat tgaaagtcaa agaaatcgag acgctgaatc
    29161 aattaaataa aaagatcaac gagatcttgc aaaaacggac aacgctgatg gaagaatatg
    29221 tcagctttga tgcatttgat gattgttata tcacgattga cgattttgcg tatctccaat
    29281 cattttcagc gcaaaatagt ttttatctgc caaattatat tttagacgag ctatttaaga
    29341 atatctccca tcgaaaagtg attttatctc cagatgaaac aatgaagatt ggtggatatg
    29401 cttataaagg cggacgcgtg attttagaga attttacgga tagtctgact gaaatgatca
    29461 atgaaaaaaa agctcagttg aagactatga cgcgccagcc gattggtttc ttctcgaaag
    29521 atgatgtttg gagctgatat tttgaagcat tgccgttgca catgagagcg tggtaatgct
    29581 ttcttttttt cttaatgata caatagaact gaacggagtg aagaaagatg ttacaaatct
    29641 atgcccatcg cggaagcagc ggcacccacc cagaaaatac gcttcctgca tttgcagaag
    29701 ctgtacgagt aggtgcagat ggtatcgaac tagatgtcca tctaagcaaa gatggttatt
    29761 tgatcgttat gcacgacgaa gaagtggacc ggacgactaa cggtaaaggg ctgattcgag
    29821 aaaaaacatt ggaagaactc aaaaaattga atgcaggggg caaattcagc aaagaatttc
    29881 cagcagctaa agttcctgaa ttgagagaag tgttaggact gctcctccaa aaaaattacc
    29941 gagggatgct aatgattgaa attaaaactg atcagtatga atatcccggt atcgaagaaa
    30001 aattagccga aacattaaaa agtagagatt ggccttttca acatgcatat tgcagctttc
    30061 atttggattc tttggaaaaa atcgcattac tggaaccgga gatacagctg gacttattga
    30121 tgagtacttc tgataaaaag atccaactag cagcagaaac cccttatata gaaggagtac
    30181 atccaaaaaa tacttggttg ttcgaacatc cagtccaggc agctgatttt ccaaaagcaa
    30241 ttcgtgcatg gacgattaac gatgaagaag aaatggccaa atgtcaagaa ctcaaaatag
    30301 atggaataat aactgatttt ccggagaaag ctcttcggtg gaaacaatca acgaaaagta
    30361 ggtaaaatat ggaaaaagta ttagtgatcg tcggtccgac agcagtcggt aaaacagcgc
    30421 taagtgtgga actcgcacaa ctatttggag gagagatcat cagtggtgat tcattgcaaa
    30481 tctataaaaa tctggatatc ggtacagcaa aaatcaaaga agaagagatg aataatgttc
    30541 cgcatcattt gattgatgtg atcgaaccta ctcaacgtta ctcagccgtt gattttcagc
    30601 attcaggtcg acaattgatt accgagattg cgaaccgagg gcacctacct atcatagctg
    30661 gtggtacggg tctctatatc caatcccttc tatatgatta tcagttagga gcgacagaag
    30721 aagcgaatcc tgagattaga aaaaagtatg aaacgttagc tgaaacaatt ggttcccaag
    30781 cattatggaa tcagttgaaa gaaaaagacc cggcagctgc tgagaaaatc cactggaaca
    30841 atcaacgcaa agtgataaga gctctggaag ttttagagac gacaggacat agtatcacgg
    30901 cacctaaaga agagccaaag caattgtatg attacctcat gattggatta gatacgaagc
    30961 gtagtattct ttatgaacga atcaatcaaa gagtcgattt gatgctagca gaaggtttag
    31021 tagcagaagc gcgtaaggtg tatgagcttg gagaagtcca ggccagtcaa ggtattggat
    31081 ataaagaatt tttcccttat tttgaaggga aagaaacatt ggaagaagca acagaacaag
    31141 tcaaactaca ttcgagaaga tacgcgaaac gtcagttgac gtggtttcgt aaccgtttgg
    31201 atgcacagtg gtttgatctt ataagtgagc caaatcaaaa aagtcagatt gagcaaacaa
    31261 tcaaaaaatg gctggaggcg gaataaaatg gaagaaaaag tgatcatcgt aggggtagaa
    31321 accgaagcaa accagcgtta cttttcagag tcaatggaag agctagttca gctgacgaat
    31381 accgcatcag gagaagtcgt attcacaatt acacaaaaga gaccacaagt ggatcggcaa
    31441 acgattatcg gtaaagggaa attacaagaa ttagttcaac aagcggatgc gcatgaagcg
    31501 gatttgatca tctttaatca tgagctaact ccgagacaga gccaactgat taccgatgct
    31561 gttggtcttc cggtaattga tcgcgtgcag cttatcttag atatttttgc gatgcgtgct
    31621 cgttcgaaag aagggaagct gcaggttgaa cttgctcagt tagaatacct gctgcctcgt
    31681 ttagtagggc aagggaaaac attatctcgt cttggcggtg ggatcggaac aagagggcca
    31741 ggtgaaacaa agttagaaac agaccgccga catatacgga ataaaatttt tgctgttaag
    31801 aaagaattga aagaagtaga agctcatcga gagcgcaatc gccaaaaaag aaaaaatagc
    31861 gagatttttc agattggact tattggctac acgaatgccg ggaagtcaac tatcttgaat
    31921 ctattgacac aagcggatac ttattcgaaa gatcaattgt ttgcaacgtt agatccattg
    31981 actaagagat ggcgttttgc tgaaggattt gagattactg taacggatac cgtcgggttc
    32041 atccaagacc tgcctacgca actgatcgat gctttccatt ctacattaga agaaagtcaa
    32101 aatatggatc ttttgctaca tgtagtcgat gctagttctc cagatcgtat tttacaggag
    32161 cagactgtct taaaattgat ggatgaactg aatatgaaag aaatgccgat actgactgtt
    32221 tacaataagg cagaccagat cgacccagcg atgttcacgc ctacgctatt cccaaatgta
    32281 ttgatttcta ctcagacgaa agaaggtaag atggcgttga tcgaagcaat caaacgtcag
    32341 ctgatggaac taatgacccc ttatacactt tctgtgccaa gcaacgaagg acagaaatta
    32401 agcgagttga gaagacaaac aatggttttg gacgaagcgt acatggaaga aacaaacgaa
    32461 tatgaagtta aagggtttgc aaaaaccaat tcaaaatggt taagaaaaaa ccaataaaat
    32521 tttatttttt taa
//
LOCUS       DAZKCH010000025        32497 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000025 DAZKCH010000000
VERSION     DAZKCH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.025"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..563)
                     /locus_tag="ACG84X_001189"
     CDS             complement(<1..563)
                     /locus_tag="ACG84X_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HFP9127082.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(750..1400)
                     /locus_tag="ACG84X_001190"
     CDS             complement(750..1400)
                     /locus_tag="ACG84X_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127083.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="ACG84X_001191"
     CDS             complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="ACG84X_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFP9127084.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2912..3910)
                     /gene="yvcK"
                     /locus_tag="ACG84X_001192"
     CDS             complement(2912..3910)
                     /gene="yvcK"
                     /locus_tag="ACG84X_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFP9127085.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="ACG84X_001193"
     CDS             complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="ACG84X_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFP9127086.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(4926..5657)
                     /locus_tag="ACG84X_001194"
     CDS             complement(4926..5657)
                     /locus_tag="ACG84X_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFP9127087.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(5661..6926)
                     /locus_tag="ACG84X_001195"
     CDS             complement(5661..6926)
                     /locus_tag="ACG84X_001195"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFP9127088.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="ACG84X_001196"
     CDS             complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="ACG84X_001196"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFP9127089.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="ACG84X_001197"
     CDS             complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="ACG84X_001197"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFP9127090.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            12268..13770
                     /locus_tag="ACG84X_001198"
     CDS             12268..13770
                     /locus_tag="ACG84X_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFP9127091.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13772..14509
                     /locus_tag="ACG84X_001199"
     CDS             13772..14509
                     /locus_tag="ACG84X_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFP9127092.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(14680..15873)
                     /locus_tag="ACG84X_001200"
     CDS             complement(14680..15873)
                     /locus_tag="ACG84X_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9127093.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDRKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVLENDTKKKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQQVMKKRPKAEPFVIDGRGNFLFVNHKGKPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(15952..16158)
                     /locus_tag="ACG84X_001201"
     CDS             complement(15952..16158)
                     /locus_tag="ACG84X_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFP9127094.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            complement(16151..17293)
                     /locus_tag="ACG84X_001202"
     CDS             complement(16151..17293)
                     /locus_tag="ACG84X_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFP9127095.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRYPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CDGVIRRFDLAINDMCGLLDIPVLSEKYRNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRGTKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
     gene            17805..18440
                     /locus_tag="ACG84X_001203"
     CDS             17805..18440
                     /locus_tag="ACG84X_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9127096.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            18594..18671
                     /locus_tag="ACG84X_001204"
                     /pseudo
     CDS             18594..18671
                     /locus_tag="ACG84X_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            18985..19032
                     /locus_tag="ACG84X_001205"
                     /pseudo
     CDS             18985..19032
                     /locus_tag="ACG84X_001205"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            19048..20967
                     /gene="tet(M)"
                     /locus_tag="ACG84X_001206"
     CDS             19048..20967
                     /gene="tet(M)"
                     /locus_tag="ACG84X_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFP9127097.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            21086..21253
                     /locus_tag="ACG84X_001207"
     CDS             21086..21253
                     /locus_tag="ACG84X_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFP9127098.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(21313..21666)
                     /locus_tag="ACG84X_001208"
     CDS             complement(21313..21666)
                     /locus_tag="ACG84X_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127099.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            22170..22589
                     /locus_tag="ACG84X_001209"
     CDS             22170..22589
                     /locus_tag="ACG84X_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFP9127100.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            22615..22821
                     /locus_tag="ACG84X_001210"
     CDS             22615..22821
                     /locus_tag="ACG84X_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127101.1"
                     /translation="MICKASSGDEMAVKEILKFYDGYISKLCLRPFYHSESGKIIMQV
                     DEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(23049..23222)
                     /locus_tag="ACG84X_001211"
     CDS             complement(23049..23222)
                     /locus_tag="ACG84X_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127102.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            23234..23863
                     /locus_tag="ACG84X_001212"
     CDS             23234..23863
                     /locus_tag="ACG84X_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127103.1"
                     /translation="MGQLSDNQQLCQERINPLLELLERVFSYYGQALLTVHRQQIIIL
                     VNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSFLHAKQVCEWIAF
                     HQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLFKKTLACFSKNNG
                     SIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLLVQT"
     gene            complement(23945..25111)
                     /gene="dnaJ"
                     /locus_tag="ACG84X_001213"
     CDS             complement(23945..25111)
                     /gene="dnaJ"
                     /locus_tag="ACG84X_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFP9127104.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(25262..27091)
                     /gene="dnaK"
                     /locus_tag="ACG84X_001214"
     CDS             complement(25262..27091)
                     /gene="dnaK"
                     /locus_tag="ACG84X_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFP9127105.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(27142..27705)
                     /gene="grpE"
                     /locus_tag="ACG84X_001215"
     CDS             complement(27142..27705)
                     /gene="grpE"
                     /locus_tag="ACG84X_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFP9127106.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(27799..28842)
                     /gene="hrcA"
                     /locus_tag="ACG84X_001216"
     CDS             complement(27799..28842)
                     /gene="hrcA"
                     /locus_tag="ACG84X_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFP9127107.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(29076..30241)
                     /gene="hemW"
                     /locus_tag="ACG84X_001217"
                     /pseudo
     CDS             complement(29076..30241)
                     /gene="hemW"
                     /locus_tag="ACG84X_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
     gene            complement(30257..30484)
                     /locus_tag="ACG84X_001218"
     CDS             complement(30257..30484)
                     /locus_tag="ACG84X_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFP9127108.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            30968..31575
                     /locus_tag="ACG84X_001219"
                     /pseudo
     CDS             30968..31575
                     /locus_tag="ACG84X_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            31748..32461
                     /locus_tag="ACG84X_001220"
     CDS             31748..32461
                     /locus_tag="ACG84X_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127109.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
BASE COUNT         9520 a         6618 c         5736 g        10623 t
ORIGIN      
        1 tctataaaca tcaccccaaa taaaacagaa aacagtataa gcattataaa aattatcaac
       61 aaccttgatc cttcttttat agattcagga aacagtataa ttttagtact agataaattg
      121 tttacaccga ttagtgttaa aatatcttta ttcttcttgc taacataacc ctttatgcac
      181 aaaagaacag ctatacttaa agtaacaaat aaataacgta ttccaataga aaaatcacta
      241 taaatactct ctagcatagg accgacaatt gaagaagtca ctactgcaaa tgctggacct
      301 atccaagcaa cattagaatg ttctttctct cttttccttt gtaaatcttt gttgagtatt
      361 aatctattta tttcttctgc aggcaagtta attttcataa ccttatgggg gattatccaa
      421 ttaaaaatcg gaaaaaggta gcctccccaa aaagtatagt gatctgtgtc aatcagataa
      481 taacctgatt ttgattccag aataacatat ctcaaagccg aacgaaaatt tttcatgaat
      541 atccataatc tcactgtttc cacacctaat tcctccaatt ccaattaaat ggatttatag
      601 catcaccaat tatgttaact gcctgaccaa cctcattgat aaaattggca ccactatccc
      661 atgcttcaac aatgctatat atctatcaaa caaaaaatgg aaaactaaat actcgcgcac
      721 ataaatttta cattctgttt tttataagac taataataat cattgaaaaa atttcttatc
      781 ggtggcgcat attcccaatt gattaatgtg atcccatatt ctgcaagtat tttacgagct
      841 tcttctaagt catagtgaga aaaatgcata aaacctgcaa tacgatcacg gactgtgagc
      901 tgtggcttgc ttccaccatc attcataaaa tatccagcag agccactact taaagtgatt
      961 gttacatctt cactttctat tattaagaat tcataatgaa atgctttcaa ctctccacta
     1021 ttatttaaaa gttttatact ccaacttcgt ctaggttgag ttgtcacatt ccctctaaaa
     1081 cttcctataa attctgcaat caccgtatct tcaatcaaaa ttctttcctc atctatttca
     1141 tattcaagac taaacggaaa ttctccatat gtaatctctg gcaatggtgg tgctgtagtt
     1201 ctccaaataa atacaataac tgtgaataga aaaaatccaa cgatcgatat aaatgttatg
     1261 agacctgctc gaagtaaaac ccgatataat aaaaatgctg tatttcgctt tgctatatct
     1321 agaaaaataa aaagtactgc aatcataatg atagtaaaag ttgtaaaaaa gcacattttt
     1381 tgccctccct ttataaacat cgattctcaa attctaaacc aaatcttgat agttcaagtt
     1441 caggtataac gtataccaac catacatccc aattactatt tatgaactta tgattatcac
     1501 tgaataaatc actccatccc cttgttaaaa cttctacatt aattacacct ggttgttttc
     1561 gactagctaa tccaatgaac ttatcaacca tccttatcca ccaaccacga gaatcttgac
     1621 cagaagtaag aaaaacagtt ctcaaggttg atcgagcagt tccttccagt ttttaattaa
     1681 tctccagtta tagataaata cttgatccta tctatatcag gacttctata ttaagcaaaa
     1741 gtttatgtat aaaactaaaa tcttcattca gttgtctccc cgctttttat acgattgtat
     1801 taaaaaacaa tagaagcctt tcaacattat gttactccag taaagttgga attatagttt
     1861 gacggaagaa aagcaagtat agcttttaaa aaaaactgat acattcgcat ctcctgcttc
     1921 atgtatcagt tttttctttg gattaaactg cttcttcacg cagtttttcc gcaaattcat
     1981 ttattttgcg aattcggtga ttaattcccg attttgatat tgcacctgag ggaatcattt
     2041 cccctaattc tttcaagctg acctctggat gttgaagccg aagttctgcg atttcctgaa
     2101 gtttttcagg aagggcatgt agaccgacct ttgcttcgat caattcgatg ttttcgattt
     2161 gtttagaagc cgcatcaatc gtcttgttca gatttgctgt ctcacaattg actagacgat
     2221 tgaccgaatt tctcatatcc cgtacgattc gaacatcttc aaatcggagc attgagttgg
     2281 ttgcaccaat caatgttaag aaatcagcaa ttttttctgc tccttttaaa tacgaaatat
     2341 agccattgcg ccgttcaagc gttcgagcat gtagaccgta ataatttaac atatcgcaaa
     2401 tgtcttggtt atgctgttca taaatagaaa atatttccaa atgataacga ctcgtttccg
     2461 gattattgac tgaacctgag gccataaaag caccacgtaa gtaagaacgc attttttgcg
     2521 aatttcccat aatctcgtcc gaaacgtgtc cattgaacat cataccatcc atgatatcaa
     2581 gatccatcaa cacatctttt gtgccttgct tcaaccggac gatatagaca ttgttctttt
     2641 ttaatttcat ttttttacga acgagtagct cacttcgtac ctgataatga tctttcaaaa
     2701 gagaatagat acgtctggca attgcagcat tttctgtttg gacgttcaaa ataaactgct
     2761 ggttcacaat acctaaagag ccgttcattc gcagcaaagc agctaattcc gctttcgcat
     2821 gttctcgatg aacttccaaa ccagttagtt ctttcttcac atctgcagca aatgacatcc
     2881 tattctcctc ctttctccaa caataaattg cttaatattt tgaaccgaaa actaaacgga
     2941 acaattcttc tactactttg tctccatcgt ggaagacacc accatctttc aattctaaaa
     3001 agtcggtgga aatcactcga catccttcat ttctcaatcc gttgaagtcg tgtgcgactt
     3061 gtactagata ctcatcatag atctctgggt ccatataatc ttcaggcact ttttccgtat
     3121 tgaccaatac tgtatcgata aaaggctgat tcaaatgctt gtgtaaaaca cgtatatgat
     3181 cggcatctgt gaaatgttcc gtttcccctt tttgggtcat gatattacag atatagacgg
     3241 tttcagcagt tgtcttgagc attgcttcgc cgatttctgg tatcactaaa tttggaagga
     3301 tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc ggcgtccata attgctgaaa
     3361 cgacttttcg agccgctttg gcttcacttt tatcatttgt gttgcagaca tacacacggt
     3421 caatggtttt acggttgatc gcgattttag attctcctac tgcagtcgtt ccgtctttaa
     3481 aaacagcatg caaggtcaaa ggagtttctg aagaaggata aacatgtcca tctacatgca
     3541 tcatttttgc taataattga atcgcctcat aagtgcttcc ccgcatctcg gaaactgcgg
     3601 caatgatcag attaccgatc gtatgattgg ctaaaaactg atcttccttt ttgaaacggt
     3661 attggaaaat atcttcatag aattgtggca tatccgataa cgccactaag acatttctca
     3721 agtcaccagg aggagccata gcgatcgatt ctctgattgc accgctgctt ccaccatcat
     3781 ctgcaacagt cactactgct gtgatatctg ctccttgatt tcgtaaactt ttcaggataa
     3841 ctggcagacc agtgccaccg ccgaccacta cgatctttgg ttttcttatc cggtaggttt
     3901 tcattttcac gaccggttca ccgtctcttt ccttttatcc ttgtcccgat gtgtcacatt
     3961 gactttatag tttttcccta aagcatttgc caaacgttca gtcaatgcca cagaacggtg
     4021 ttgaccgcct gtacagccga ttgcaactgt caagctgctt tttccttctt taatgtatcc
     4081 aggcaataca gtttccagaa gatccaaaaa tttatggtag aatgattgcg tttcatcaaa
     4141 ggacatcaca taatcataga ctggctgatc ttttccggtc aatggtctta gttccgggat
     4201 ataatgaggg ttgggcaaaa aacgcacatc catcacaata tccgaatcga tcggcaaccc
     4261 gtatttaaaa ccaaatgata caaattcgat ccgaaatcct tggtctccct ttgatttgaa
     4321 tgactcattg attttttcac gtaattgtcg tggtgtcaat gttgtcgtat caatgatcac
     4381 ggaagcttgg gctttcaagt cgtctagtat cgcccgttct ttacgtatcc cttcagtgat
     4441 caaaccgtcc atcgccattg gatgtgctcg tcttgtttct ttgtagcgag ccactagttc
     4501 ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg aagttcgtat tttcgatttc
     4561 gatcagcatg ttttggattt cttcaaagaa ggaacgagaa cgcaaatcca ctcctaaagc
     4621 catttttgtg actttacctg attctttgat caattcccag aattttggaa tcaatcgagg
     4681 cggcatatta tcgatacaaa aatagcccat atcttcaaaa ctttggatag ctactgtttt
     4741 ccctgcacca ctcatacctg ttatgatgac taattgcaaa ttatctgtca tatttacgaa
     4801 cccctctcac attgtgcata ataaaattat atcatcccgg gcgtatcatt accagttttc
     4861 tttttctttt acaaaaagat ttggaccaaa tatcttttag gatatttgcc ccaaatccaa
     4921 tttttttact tttccgatgc tgtatccaat gcctcgcttc tttcagctaa tgcacgttcg
     4981 atcgttcgat ccgctaaaat agattgagca tcgatcactg ggtaatgatt atcttcagca
     5041 aattcatgca tcaaagataa ttctgtgcaa cctaggatga ctttttcaca gtttaggcgc
     5101 tctaccgctt cctctaagat ttcgtaatag agctcttgat tcaaataatc cgattccttg
     5161 atctcatgat agatcaggta attgattttt tcttgaagcg cagtatcagg aatcactgtt
     5221 tcgaaaccaa gatttttgac ttcgcgttca tagattccag ctttcatact tccttctgtt
     5281 cctagaatcg ctactctccc tgtcgtatgc tgacggacaa gttcatttgc tgcttctctt
     5341 ggcatatgca agataggaat atccgttgcc gcttgtaact cttcaaaaaa gtagtgtgcg
     5401 gtgttacaag tcaacacaat gaagtttggt cgcaataaat tttgtttctc aatatcatcc
     5461 agcagaaacg gcattggatt ttcttctgat cgatctaaaa tataagctgt acgatcagga
     5521 actgttgcat gattgaataa gacataattc aaatattctt gatcttttgt agctttcgtt
     5581 cggtggttga tcaagcgaac aaaactttct gtcgccatcg tgcccattcc gcctaaaata
     5641 ctgaaaaaat tctccatgaa ctagccttct ttcacatgaa aatacttttt gaatcttgga
     5701 atatagttat ggaacatata tttcatcaac aaccagcgct tgattgatcg gtctttttca
     5761 taaaatacag tagtaccgta acgattttct ttgatcattt gctcagctag ttttttgtct
     5821 tcattttccc gagcatattc taaaaagatt tttttgggca cacccatcca taatcttgct
     5881 ttatctgatt gattcgttcc ataggtcgtt tcaacaaagg gtttgttgaa cactcgatct
     5941 tctgtgacaa aacgagccag attcaagccg ttcaatgtca caaagaaact gctacgacct
     6001 tgtctcaaat tgatttcaaa taatttatat tctccatctc taggatcata cttcatatcg
     6061 aaattggcaa agcctgtata ttcgattttt tccaaaaatg ccttaatggt ttgatagatt
     6121 ttttcgttat aatctggcat gatcacaacg taattaccaa tcgatgctgg tgtaggatct
     6181 tctaatagtg gatgaccaag gcacatcatc cgaacttgat gatcttcatc tacatacgca
     6241 tttagcacac gcatattact atcatcaccc gggataaaat cttgtacaat catttcactt
     6301 ttataaccgg cttcgtatat ccggcctaaa attaaatcga actcttctct agtctctaaa
     6361 ataaaagctt tttttcttcc ttcaaattgg acagaaagat actccacact gtttgcaggt
     6421 ttcaaagcaa ctgggaattc aaaaggcaat tcctgttcca aatgtccatt tactaacatt
     6481 tcttctctga cgatcaatgt tttaggatac ggaagatcat attcttcaca aacttcataa
     6541 aagcttactt tattgatcag cctttcaaat aaagaataat caatatatgg acagataaaa
     6601 tattctgaca gctcttgttt atgttgggag atcaattctg catatccatc accacaagca
     6661 atcaaaagat attttttact cttatcagaa tatctttctt ttgccaaacg aagcatcgtc
     6721 tcgataaata cagggtcttt atcaaatcct ggaataactt ctacattgac aattttactg
     6781 tagcgggtag gggctaactg atccgaagca tatgcttggc agattttgcc gtatgcttca
     6841 ttaaaagaac gtgccatacc ataaacgttc atgtcgcttc ctaataatat agggataaat
     6901 tcttcatttt caatactgtt catcattatc tctcacttac tcataatctc ttgtttttct
     6961 tttccaacta cacaaggaat atcataccat aaagaaaaaa gcaatcaaag gaaagtcctc
     7021 cgattgctca attctttttt gaacggattg aacttatagg aagtttttat ctataccaat
     7081 cagtgtagaa agaactacca tgtaatgatt ctagaacact gatattaata aaacaagcaa
     7141 aaattcattt ttttatgttt ttttaactat ctcagctatc tatcctcttt ataccattat
     7201 ttttttcaaa tagtgacctg tataactttc ttttacgtta atgatttctt ctggtgttcc
     7261 agtcgcaagg atcgttcctc caccttctcc accttctggt cctaaatcaa tgatataatc
     7321 tgctgttttg attacatcta gattgtgttc aatcactaaa actgtgttac cagcatctac
     7381 taatctttgt aatacatgca acaagcgggc gatgtcatcg ctatgaagtc ctgtcgttgg
     7441 ttcatctagt atatagaaat tctttccatt agagattttg tgcaattcac tggcaagttt
     7501 catccgttgt gcctcaccac cggacaatgt cgttgctggt tgccccatcg tcacataacc
     7561 taagccaaca tcaacaatcg tttgcagttt gcgatgaatc tttggaatgt gcttgaagaa
     7621 ttctacagca tcctctactg tcatttccaa aatatcagca atgctttttc ctttgtaatg
     7681 cacttctaat gtttcagaat tatatcgttt accatgacat acttcacaag gaacatagac
     7741 atcaggcaaa aagtgcattt cgatcttaat aattccatcc ccgcgacaag cttcacaacg
     7801 accgcctttt acgttgaaac taaaacgccc tttcttataa ccccgcattt ttgcctcgtt
     7861 cgtttgagca aataacccac ggatatcatc aaatacactt gtataagtcg ctggattact
     7921 tctcggcgtc cggccgattg ggctttgatc gatatcgatg atcttttcga tactttcgta
     7981 gccggaaatt gtcttgaatt tacctggctt agcagaattc ttatttaatt tttgcgctaa
     8041 cgatttcttt aagatactat tgaccaatgt actctttcca gaaccagaca cacctgtgac
     8101 tgctacaaat tctcctaatg gaaattcaac actaatattt ttcagattgt tttctgaagc
     8161 accagtgatc ttgattgctt tcccattacc tttacggcgt tcttttggta cagggattga
     8221 ttttttccct gaaagatatt tccctgtcaa agaattttca tcattagcta cttcttcagg
     8281 agtgcctgca gccacgattt gtccgccttg ttctccggcc ccaggtccga cgtcaatcaa
     8341 ataatctgct gcccacatcg tatcttcatc atgttcgact acaacgaggg tgttgccaag
     8401 atcacgcatt ttctttaatg agccaatcag tcgatcgttg tcgcgttgat gcaatccgat
     8461 cgatggttca tctaaaatat acaaaactcc agaaagattc gatccaattt gtgtagccaa
     8521 tctgattcgc tgcgcttctc ccccagataa tgttccggaa gcgcgactca aagttagata
     8581 gtctagtccc acattttcca agaatgaaag tctgtcattt acttctttta aaatcggttt
     8641 ggcaattact ttctcttgtt cagataacgt taagtttgag aagaaatcta ctgctttttg
     8701 aatagacaac tcatttgttt gcccgatatt cgttccattg atttgaacag atagagcttg
     8761 gggattcaat cgataacctt tacatgtctg acaagttaat tctgtcatat aaagacgcat
     8821 ttgctcacgc gtgaaatcac tgttcgtatc atgataacga cgctcgatat tcttcaatac
     8881 cccttcgaaa gtcgtttcta catcgcgaac gccaccaaaa tcattttcat aatggaaatg
     8941 gaaaagatca tctgtcccat tcaagatgat ctcctgatgc tcttccggta attcttcgaa
     9001 tggtgtatct aaatcgatac cgaaactttc acaagcctgc gctaacattt gaggataata
     9061 ctgagagctg attggattcc atggaacgat agcaccttga ctaagtgtct tcgttctatc
     9121 tggaatcact aaatcttgat cgacttctaa tttgacacct aaaccatcac agtctggaca
     9181 agctccaaaa ggcgcattga atgagaacag tcttggttct agttcgccaa cagtaaatcc
     9241 gcaataagga caggcatagt gttcgctaaa caacatttct tcttcaccga tcacgtcaac
     9301 cagagcatag ccgtctgcta atcgcagggc cgcctctaaa gaatcaaata ggcgagaacg
     9361 aatcccttct ttcacaatga tccggtcgat gacgatcgcg atatcatgtt ttttgttttt
     9421 ctccagctca ggcacttcac ttaaatcata gatctcacca tcgactcgaa cgcggacgta
     9481 tccctctttt tggattcgtt cgaatatttt tttatgttgt ccttttttct ttaccacgat
     9541 cggtgccaac acttggatct ttgtgcgctc aggcaaagcc attacttgat ctgccatttg
     9601 atctactgat tgactggtaa tctcgatatg atcgttggga caaatcggat gtcctacacg
     9661 tgcaaacaac aagcgtaaat agtcattgat ttccgtcaca gtacctactg tcgaccgagg
     9721 atttttactt gttgttttct gatcaataga aatcgccgga ctcaatccgt cgatgctatc
     9781 tacgtccggc ttatccattt gtcctaaaaa ctgacgagca taagcagaaa ggctctctac
     9841 gtatctccgc tgcccttcag cgtacagcgt atcaaatgct agggaacttt ttccagaacc
     9901 ggacaaacct gtaacgacca cgaatttatc tcgtggaatc gttacatcta tatttttcaa
     9961 gttatgggca cgtgcaccat gaatcgtaat tttatcgtta gccatgttgt cctcctactt
    10021 tgaagctttt aattctaaaa tcatatctcg cacattcgcg gctgtttcaa aatccaaagc
    10081 ttttgccgca tctttcattt ctttttctaa tttcatcaat aacgtgtctt tttcttcctt
    10141 cgtcatttct tcgtacgaga cttgtaccgc ttcttttgta tcatcttccg attctttcgt
    10201 aatagaaatc aaatctcgga tttctttaat gatcgttttt ggaacgatcc catgttcttc
    10261 attgtacttc tgctgaatcg tacgacgtct tgacgtttca tccatcgcta gacgcataga
    10321 atctgttact ttgtctgcgt acatgattac tttaccttct tcattccgag cagctcgtcc
    10381 aatcgtttgg actaaggaac gttcactacg taaaaagcct tctttatccg catccaagat
    10441 agcaacaagg gaaacttcag gtacgtctaa tccttcacga agcaaattga ttccaactaa
    10501 cacatcaaat tcacctaatc gaagatctcg aatgatttct gttcgttcca gcgttttgat
    10561 atcactatgc aaatatttga ctttgatccc taattctttg aaataatctg tgaggtcttc
    10621 tgccattttt ttcgtcaatg tcgttacaaa cacccgctgg tctttttcga ctcgttcatt
    10681 tatttcgcct actagatcat cgatttgtcc catgattgga cgaacttcga tcactgggtc
    10741 aagcagccct gtcggacgga tgatttgttg gataacggta tctgtttgtt catgttcata
    10801 tggtcctggc gtcgcagaga cataaatgat ctgattgaca tgtttttcaa actcttctaa
    10861 ccgaagtggc cgattgtcta aagcagatgg caaacggaaa ccgtaatcta ctagcatctg
    10921 ttttctcgct cggtcaccat tatacattcc tctgatttga ggcatggtta cgtgcgattc
    10981 gtccgccacg atcaaaaaat cttcaggaaa gaaatccaat agcgtataag gcggttcacc
    11041 ttctttacgt ccgtccatat gccgagaata attttcaatt cccgacgtgt agcccatttc
    11101 taacatcatt tcaatatcgt aattggttcg ctgttctaaa cgttgagctt ccagaagttt
    11161 gttttcattt cgcaagacag ttaaacgctg ttctaattcc tctttgatat tcgctacggc
    11221 atgctccata tgttcatcat tcgtcacaaa gtgagtcgcc gggaagattg ctacgtgttc
    11281 cgtttctcct aaaacttcac ctgtcagtgc attgacttct cggatacgtt cgacctcatc
    11341 tccaaaaaac tccacacgta aggcacgttc atctcttgaa gccggaaaaa tctccacgac
    11401 atcaccgcgc actcgaaaac gaccgcgctg aaaatctata tcatttcttt cgaattggat
    11461 actgactaag tcacgaatca actgattgcg atctagttct gctccctgtc gaatcgaaac
    11521 tacttgtttt tggtactcaa aaggcgagcc taatccaaaa atacatgaaa cggatgcaat
    11581 gacgatcaca tcatttcttt ctaataatga actagtagcc gaatgtcgta atttgtcgat
    11641 ctcatcattt acacttgaat ctttttcgat atacgtatcg cttgaaggca cataagcttc
    11701 aggctgataa taatcataat aagaaacaaa atattcaaca gcattgttag ggaaaaattc
    11761 cttgaattcc ccgtacagct gaccagccaa tgttttgtta tgggcaataa tcagtgttgg
    11821 tttattcact ttctcaataa gattggaaat cgtatatgtt ttccctgttc cagtcgcacc
    11881 taataagatt tgtgcttttt tcccgccgac tacgccatcc actaattggt taatcgcttc
    11941 aggctgatca ccagccggtt ggtatttcga gacaagctca aagtgtcggg aggtatctct
    12001 ctcaatcatt cttcgtcctc cttttcattc attccttttc attttacgac caataaaaag
    12061 aaaaggaaag caaaggcatt ccttactaaa aaattatacc acaccgaaca tactttcgcc
    12121 acttttttat cttattatac atgttatgtt ttataacata aaatgttaga aactcgcatt
    12181 tttttcattt tttcgagctt acagtcttgt ctgattcagc acttttcgcc tataataata
    12241 aaatattgga aatttaggag gttgattatg aaaagaaagc atttatttca ctcatttgtt
    12301 ttcttaatga caggacttgt gacacttgcg tttggtcatg ttgcacaagc tgacaacact
    12361 acaacggcag agtcaagcac aagcgagaca atgcaaaaaa tagagcccaa aaaagacgta
    12421 tacgtaattg ccagtgactc tgcttttgct ccatttgaat ttcaaaacgc aaagggcgag
    12481 tacgaaggca tcgatgtaaa attgatggaa aacatcgcca aactgcaagg atttaacatc
    12541 cgaatggact accgtggttt ctctgctgct ttgcaagctt tggaatcagg acaagcagac
    12601 ggaatgattg ccggaatgac tgtaacagat gaacgaaaga aaagctatga tttttctgat
    12661 tcttactttg atagcgggat ccaattagct gtcaaaaaag gagatacttc gatcaagtct
    12721 tatgaagatt tgaaaggaaa aacagtcgga gcaaaagttg gtaccgaaag tgctgaattt
    12781 ttaagcgacc atgaatctga atatggctat tctatcaaat attttgatgc tgctgatcaa
    12841 ttgtacgacg ggttaaaagt tggcgcaatc gatgcaatga tggatgatta tccggtaatc
    12901 ggttatgcga tcaaacaagg acaagaattg gaaacaccga tcaaaaaaga atctggcgga
    12961 aaatatgcat ttgccgttaa aaaaggacaa aatcctgagc ttcttaatat gttcaatgaa
    13021 ggattgaaag aattaaaaag aacaggcgaa tacgataaga ttattaaaga atatgtagcg
    13081 gatggttcag aaacttccag tgagtcttcc actgctgatg aatcaacatt tcttggactt
    13141 atccaaaaca actatcaagc attgttgaaa ggactttgga gaacaattct cctaactttg
    13201 atctcctttg ctttggctat agtaatcggt gtgatttttg gattattcag tgtagcacca
    13261 atacgcgctc ttcgcacaat tgctagtatt tatgtcgata tcatccgagg aattccaatg
    13321 atggttcttg cgttctttat tttctttggg ttgcctggta tcgttggatt tacgattcct
    13381 gacttccttg ctggtgttat caccttgact cttaacgcaa gtgcttatat cgcagagatt
    13441 gttcgaggcg ggatcaacgc cgttcctgtc ggacaaatgg aagcttccag aagtttaggt
    13501 ctttcttata atcggacaat gcaaaaaatc attttgccgc aagcgatacg catcatgatc
    13561 ccatcattcg tcaatcagtt cgttatctca ttaaaagaca caacgatcat ttccgcaatc
    13621 ggtgtagtcg aattgctgca aactggtaag atcattgttg cacgtacaac acaaagtacg
    13681 tatgtttact tgatcattgc gatcatgtac ttgattttga tcacagcatt gacaaaatta
    13741 gcaaaagttt tagaaaagaa ggtgaagtaa gatggcagaa aaaatcttag ttgagcattt
    13801 agtcaaaaaa tacggcgata acacagtatt aaacgacatc aatgtatcca tcaacgaagg
    13861 agatgtcgtc tgtatcattg gcccttcagg ttcaggaaaa agtacattct tgcgttgctt
    13921 gaatcgttta gaagaacctt ctgacggtga aattattatt gacggcgccc acttgatgga
    13981 taaaagcaca gatatcaact tggtgagaca acatatcgga atggtattcc aacactttaa
    14041 cctattccct catctttcta ttttggaaaa catcatttta gcaccgatgg acctgaagaa
    14101 agaatctaga gaagaagcag agaaaaaagc aatcaaatta ctgcagacag ttggtctaga
    14161 agataaaaaa gatatgtatc ctgaaatgct ttctggtgga caaaaacagc gtgtggctat
    14221 tgctcgtgct ctagcgatga accctgacat catgcttttt gatgagccta cttctgcact
    14281 cgatcctgaa atggtcggtg atgtcttgaa cgtcatgaaa aagttagcag aacaaggtat
    14341 gacgatggtt atcgttacgc acgaaatggg gttcgctaaa gaagtggcca atcgcgtcat
    14401 gttcattgac gacggaaact ttttagaaga tggaacgcct caacaaatct ttgaaaatcc
    14461 gcaaaatgaa cggacaaaag atttcttgaa taaagtatta aatatttaaa ataaattata
    14521 tatgtctttt tgactatctt tttatatctt cttaaatgtc cgcaaagcct tattttatag
    14581 gctctacggg cattttgctt ttgtggtaaa cctcacatat ctaggtctat cttcttatat
    14641 tttcactatc aagcgtggtt aaaatcgtgg taaatacttc tatgcaatta gacgctgaac
    14701 ctctgatttt gcggtatcta tggacgcatg agcataccag ttcattgtga tactgatatt
    14761 tgaatgcccc atgatatact gtaaatcttt tgggttcatg ttcttgcttg ccagtcttgt
    14821 gcagaatgta tggcgtagcg tatgcggtgt gatatgtggc aatggattgt ccttgtggtg
    14881 cttgttgtat ttctttacca tacggataaa taaggcgtta taatcaatcg caactttggg
    14941 cttgccctta tgattgacaa ataggaagtt gccccgtccg tctatcacaa atggttctgc
    15001 ctttggacgt tttttcataa cctgttgaaa tgcctgtatc gtttctttgc ttaatggtac
    15061 ttgccttatt ccgctttttg ttttaggcgt ttcaatataa tagccctgtt ccttgctctt
    15121 tagtaactgg tggtcgataa tcacaacttc attcttgaaa tcaatgtcgg ctactgtcag
    15181 tccgcacagt tccgaaatac gaagtcctgt ctttaacagt atcagcacat catcataatg
    15241 cttgtgatac acattgtccg tcttgatgaa tgagagtaag gcttgttcct gttcctctgt
    15301 caatgcgact ttctttttgg tatcattttc taggacttca ctcaacttga aatcaaaggg
    15361 atttttcctc acataatcat cttgaatggc tatgtagaat gacgctttta acgagcgttt
    15421 atggttgtta atggtattgt aggaaaagcc tttgtctttc atgcgtaacg cccattcctt
    15481 agcgtcagag ggtttgattg tatcaatgct cctagcacct aacttgtcct ctttcaataa
    15541 ccgcatgagt tgttcccgtt gtttctgtgt gcttttcttc acatttgccc tctgtgcgtt
    15601 ctgtttggca taaagttggc aaagcgtcat tttcttgcca gtgctgtcga taccgtcctc
    15661 aatatcccgt cttatctgct gttccagttc tcgaagtgag ggtttttccc gttttccctt
    15721 tggtgtcggg tctgtgggtg tcaatctcca agcatacaca tattttgtgt ttccaaatgc
    15781 gtctacatat ttatataagt attttctgtc tgttcgttgg ctctctccag tatgcaggat
    15841 acgacctttg ttatcccgtc ttttttcttt catggtgtct gctcctttcc ttgttggaaa
    15901 gagccttgat atgacttgtg ttcatcataa cacatacaag gctcatttgc attagatagc
    15961 gtccaattta tcaatgacct gttcaaactg tcggcgttta atctgtatgc ggttgccatt
    16021 cataatgagc cagccagcgt ccttgttttc ctctgccaat cgtcttaact tgttttctcc
    16081 gatacggaaa tactttgacg cttcttcaat ggtaagggtg tatttttccc atacgggaat
    16141 atcctgtgca ttactcataa aacaccccct cactttcgat tacgtctgct atgtccgtac
    16201 acatctgttc cacaagcatt tcctgctttt cagagaggtg ggtacattca tcaatcattt
    16261 tcatgtagtt tgagcctgtc agcctgtcga tttcctctat catcacgatt gacggcatga
    16321 cctgtctttc cagccattgc agagtgcgtt ccatattgac aggtacgggg ttcatttcaa
    16381 aaggtaaact gtcatgggaa atgaatatct cccacagcgg atagtcggga aattgcacaa
    16441 aatcagtaat aaggtaaaac accagcccat gagggttata tgtcaataac aattcctcaa
    16501 ctgcctgtac tgcttttgta ccacgcagac gaatttcaaa acgattgata atatccgtat
    16561 gtttcttttt ggttgcctgt tccttttgtt tttcatacag gcagaagtat tttgtgcttg
    16621 cctttgaacc gatataaagg gtgcttgcta aattacggtt ttttccgctt agttttccac
    16681 cctgcacatt ttcataattt ttacagcgac aatccgcacc gccatttctg tatttttcag
    16741 acaaaacggg aatatccaac agaccacaca tatcattgat tgccaagtca aaacgtcgga
    16801 taacaccgtc acagtcaaga cagcggttta aaaatgaata ccaatctctg ttctgtgcct
    16861 gcaagacata ttccatgttg cgtgagcctg ccccttttaa ttccaagaat acgcccatgt
    16921 gttcgtcatc agaagccatg accttgattt ctccgtaggc gtaatgctct ttatagccat
    16981 aatacccata gtcataatgg ataaaataat ctgctttcat gccaagcacc tttcggataa
    17041 tttccaatgc gtcagtcgtt ggataacgga cagacagata atcaacgagc agataaaaag
    17101 gcttatcgca gatataataa ttcagacaac gcaggataat attttgtgtt tccttgctgg
    17161 cgttggcttt tccgttctca aagcggttga tactatatct tgatacatgg gtaagacttg
    17221 caagttctcc ttgtgaaaga ccgcttgcaa gacgtttgtt cttcatttca agtgcaaatt
    17281 ctaaattgtt cattgtattc ctccaatccc acaatagcct tgaaatacct gtaaacctct
    17341 attcaaaaag tgtgatatgc actatcttct taaaacttct cattactact cacaactttg
    17401 ggattgtatg gtttttgact tgtcttttgt gaaatagtgc ccccctgtta gataacgggg
    17461 gcacagacaa ggctcgcagg ctcgccagcc gacaaagcat ttcttcccct tgacacaagg
    17521 tgtcatggcg gtaagcctga gaggcttccg ccaccgtgtc agaaatactt tgtcagcaag
    17581 ttctgttttg ccttttctaa caagttccat ttcaaccgat attcatatct acggatttaa
    17641 tcagataggt atttcttttt gaatgttttt atatttcatt ctattgtgct tattcgatta
    17701 caagaacata gtaattctta tatgcttatt tgtcaatatc tttttttgcc tttacaaatc
    17761 atattaagca tgatagactt ataatagcga agatataacg agatatggag ggttatgcaa
    17821 tgaaaataag ccatttagga aataatatac agaccataag aaaatttagg ggaatgaaac
    17881 aacaggaact tgcggacaaa atcggtatca atatgcagag cctttccaag attgaaagag
    17941 ggttgaacta tcctgcctat gaaacgctgg aaaagataat ggaagtgctg gacgttacgc
    18001 ccaatgaatt gttgtcggga gaatggaagt atgtcaatca atctgaaaag gaagtctgtc
    18061 agtttttaag agccgaagaa cgtctaaatg cagaactgaa acatggacac tatgataact
    18121 tctttgacag cgaggaagaa tggctggaat atgagttaga aaagttacgg gaatatatta
    18181 cagactatat caacgggaaa agcattgaag cgtccgacct ttacccaatc aaagaattta
    18241 tccagcattt gaagtttcaa aaattattag accgctatga tgatttatac agtatggata
    18301 tgtttgggga aagcatagag ggacataagt ataagacacc ttatcaagtc gtgaaaatga
    18361 taaacccgaa ctcaaaagaa gatatggaac tgttacgaga agtattaagg aataacaatt
    18421 ttgatgatga ggacgagtaa cttttttcct cttgcgagaa gatacagcaa acaaaaagcc
    18481 cgatcaagag tgcaaagcac caccaatggt ggcaaagctc ttgacagggc tttttctttt
    18541 ctgttgtggg caatcaagag gaagaaaggg ataaaatctg atttgtggta aatcaggcaa
    18601 aggcaacgca ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt aattggaaga
    18661 ttatagaata acaaatattg gtacattatt acagctattt tgtaatcacg tactctcttt
    18721 gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt taagtatcta
    18781 tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag
    18841 tgggaacaaa taattggatg tcctttttta ggagggctta gttttttgta cccagtttaa
    18901 gaataccttt atcatgtgat tctaaagtat ccggagaata tctgtatgct ttgtatgcct
    18961 atggttatgc ataaaaatcc cagtgataaa agtatttatc actgggattt ttatgccctt
    19021 ttgggttttt gaatggagga aaatcacatg aaaattatta atattggagt tttagctcat
    19081 gttgatgcag gaaaaactac cttaacagaa agcttattat ataacagtgg agcgattaca
    19141 gaattaggaa gcgtggacaa aggtacaacg aggacggata atacgctttt agaacgtcag
    19201 agaggaatta caattcagac aggaataacc tcttttcagt gggaaaatac gaaggtgaac
    19261 atcatagaca cgccaggaca tatggatttc ttagcagaag tatatcgttc attatcagtt
    19321 ttagatgggg caattctact gatttctgca aaagatggcg tacaagcaca aactcgtata
    19381 ttatttcatg cacttaggaa aatggggatt cccacaatct tttttatcaa taagattgac
    19441 caaaatggaa ttgatttatc aacggtttat caggatatta aagagaaact ttctgccgaa
    19501 attgtaatca aacagaaggt agaactgtat cctaatatgt gtgtgacgaa ctttaccgaa
    19561 tctgaacaat gggatacggt aatagaggga aacgatgacc ttttagagaa atatatgtcc
    19621 ggtaaatcat tagaagcatt ggaactcgaa caagaggaaa gcataagatt tcagaattgt
    19681 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
    19741 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
    19801 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatat acgcctttat
    19861 agtggagtac tacatttacg agattcggtt agagtatcag aaaaagaaaa aataaaagtt
    19921 acagaaatgt atacttcaat aaatggtgaa ttatgtaaga ttgatagagc ttattctgga
    19981 gaaattgtta ttttgcaaaa tgagtttttg aagttaaata gtgttcttgg agatacaaaa
    20041 ctattgccac agagaaaaaa gattgaaaat ccgcaccctc tactacaaac aactgttgaa
    20101 ccgagtaaac ctgaacagag agaaatgttg cttgatgccc ttttggaaat ctcagatagt
    20161 gatccgcttc tacgatatta cgtggattct acgacacatg aaattatact ttctttctta
    20221 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
    20281 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
    20341 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
    20401 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
    20461 tcgtttcaaa atgcagttat ggaggggata cgctatggct gtgaacaagg attgtatggt
    20521 tggaatgtga cggactgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
    20581 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
    20641 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
    20701 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
    20761 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
    20821 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
    20881 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
    20941 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
    21001 tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa aggaggagat
    21061 agttattata aactacaagt ggatattgtg tcctgtatgt ggaaataaaa cacgattaaa
    21121 gataagggaa gatactgaat taaaaaaatt ccccctctat tgtccgaaat gcagacaaga
    21181 aaatttaatt gaaataaagc agttcaaagt aactgtgatt acagagccag acgcaaagac
    21241 gcagagccga taaaatgaga ttaatacaat ctcattttat cggctctttc cgttatgtat
    21301 ggattctttt aattagtctt cgatgtttct tgcttcgttg ataccgctgg ctaaagattc
    21361 cattaaggat agttctttgt ctgtaaagct atccatgtat ttctctatct gtaatcgtcg
    21421 ggtgcttttt accaagttat tagcaggtaa gaaaaattca tcaacggaaa catgaagtaa
    21481 cgatacaagg tcataaagaa cttgtatgct ggggtgttgc cctttatttt caatattagt
    21541 taagtaccgt gggtcaattt caatcaatgc tcccacttgt tcacgagtta aacctcgttt
    21601 caatcgagct tctttaatgg ctaaaccaaa ggctctaaaa tcatatttat cttctttttt
    21661 acgcatagta gaccacctct atacatttta ttgttcctac tgaattaaaa acaggtatag
    21721 aaaaacgtgt tatatggttt ataggtttat atttaataaa aagcactact aaacgccaat
    21781 aaaaaaaacc gttatatggt agtgctattt acgctgttaa aatattgtat attacttcca
    21841 aatggcggtt tgttggaggt caacgtcgcc atgaagtaca tcatatacaa taaatttcct
    21901 tacattgggt tcttgtcaaa aaaagtcgtc tatctgcaat agataagtac gtccaccaat
    21961 gtggttttat aaatcatata gatagaataa cagaagcatg taaacagaga aataaatctg
    22021 tttatatgct tttttggcta ttcagaactt ttttacaaag tttatttatc agtaatgcaa
    22081 caaatccccc tttcacattg ggactaagag tgaaaggaga taaacgagca aggctcactt
    22141 cctttcctag acagaaaggg ggtgagatta tgaggacatc ttctttcgag catatcgtca
    22201 gattacagtt caattcttta atgctgattg tcattaagaa caaagtgaaa agtcgaaaca
    22261 gacagcttgc aagacattct aaacgtgaag tattgttttg tgaaatagcc gaaacgaaac
    22321 aagttgaacg tggaacgatt gatacctgtt tttatgattg tgtatcattt aaagtcttgc
    22381 actttacaat ttatgtatct gatgaaacac ttggtacagt tttacataga ctatcagaaa
    22441 aacagcgtag tgcgatttta ttacgttatt ttcaaggaat gaacgacaga gaaatttcag
    22501 aactgtacca tgtatcacgt tctgctattt gcagtagaag aactagagga ctaaggaagt
    22561 taaaaatgct tttgagcgaa aggaagtaaa gattatggct atccctcttt tgaattgatt
    22621 tgcaaagcgt caagcggaga tgaaatggca gttaaagaga ttttgaagtt ttatgacggt
    22681 tatatttcta aattatgctt gcgtcctttt taccactctg aaagtggtaa aatcattatg
    22741 caggttgatg aagaactaaa aggagaaatt catacagaca tgatgaaagc aatattgaaa
    22801 tttgaaatcg gagtgaagta atcaactgta taaaaaaatc gggagataca cagtttcgtg
    22861 ttatctccct tagtagtttt acggtcatat caaggctcat tcaatcgtgg taaattcgtg
    22921 gtaagatgag tgtttttcta tacttcaaaa tgcttgaatg tatagtgttt atgcggataa
    22981 ttgaaaatta gatataaaat ttaataaaaa ccaaaaatgc acggtcgcca tgaagggacc
    23041 gtgtattttt atcttcttat tttctcacct aatcgtatca gccgcatcgc ttgttttcct
    23101 gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat cggttcattg
    23161 atgatatcaa gtacatagtc gataccaccc tcacttaatt gagcttgatt tttcttctcc
    23221 atattatgta gttgtgggac aactttctga caatcagcaa ttgtgtcaag aacggatcaa
    23281 tcctttattg gagttgctcg aaagggtctt ctcttattac ggacaggctt tgctcactgt
    23341 acatagacaa caaatcatta tcctagtcaa tcggatttcc agagcctcat tgctatcatt
    23401 gcttgataaa atccagacaa agtttaataa aatgtatcag ttacagctaa actttggaat
    23461 tgggtcgctt tgttatacag agcaagagac accgcaatct ttccttcatg ccaaacaagt
    23521 ttgcgaatgg atagctttcc atcaatctgt gaacgagatc cgcttttttg aagatttaga
    23581 cctcgggatc gttttaccag caatcccgtc agatcaacga acattatatg taaaacgtat
    23641 tttgaaaagc ctgacagaag aagaagtaca tttgttcaag aagactttgg catgcttcag
    23701 taaaaataac ggaagcatca aaaattgctc agaagaatta tttattcata aaaacacctt
    23761 gcaatatcga ttgaacaagt tccattctct cactggttat acccctagaa actatgacga
    23821 ttatcatatt ctaaagctgg cttttttgtt ggtacaaaca tgacaactac aaaaaaacca
    23881 ggcgaacata tgattgttcg tctggttttt aattattaat gacttagcgt ttttactaga
    23941 aaaactactt ccgctttttc ccgccaaaag catctttaaa cttatcgaag aaaccgtctt
    24001 cttgctgttc ttcaactttg atgccgccag cttcagcgaa tgcacgtaat gcttctcttt
    24061 gttgttcatt tagatttttc ggtgtgatca gttttacttt gacatgttgg tcgcctgttg
    24121 caccaccacg taacttcgga gcgccttttc cacgtaaacg gaagttcgta cctgtctgtg
    24181 ttccagcagg gatcttcaat ttcacatctc catggacagt tggtacttgg acttcatccc
    24241 ccaaagctgc ttgtacaaaa cttaaaggca attcatagta aatttcagaa ccttcacgat
    24301 caaagatatc actttcttct acacggaaga ccacatacaa atcaccaaat ggtccgccgt
    24361 tttctccagc ttctccttga ccagctaaac gcatttgttg tccttcttct acaccagctg
    24421 gtacattcac tttaactgaa tgtgctttct tctcatgtcc tgagccatga caggttggac
    24481 aaggttcttt gatttctttc cctgtcccat gacaaacatc acaagtttga cggctcatca
    24541 ctcgtccaag tggtgtttgg cgttctacat taatcgtacc tgcaccatga catttatgac
    24601 aagtagttgg ttgtgtgcct ggttttgcac cgttcccacc acaagtatga cagatttctt
    24661 cccgattata cttgatttct ttttctacac caaaaatcgc ttcttcaaaa gacaagtcga
    24721 ccgtatattg caaatcagca ccttgacgag gcgcatttgg atcgactgac cgaccgcctc
    24781 ctccaaagaa agagtcgaag atatcttcaa aaccaccgaa gccgccacca gagaagccgc
    24841 cgaatccacc aaatccgcca ccagctccac cagcaccgta atttggatct gtgcctgcat
    24901 gcccgtattg gtcatatgca gcgcgttttt gcgggtcact taaaatctca tatgcttctg
    24961 atacttcttt gaatttttct tccgcatcag gttctttatt gatgtcagga tggtattttt
    25021 tcgaaagctt acgataagct ttctttattt catcttctga tgctcctttt gagagcccta
    25081 agacttcata ataatcacgt tttgttgcca taggctttcc tcctattggt tctcatcatt
    25141 ttcacgtcgc ttgttatcat atcatatttt gtttgaaaca aaaaccgata cttcaaacta
    25201 tttttcaaaa gaaaaagcca aagtagcaac tttggccttc tctcgaaatt cagtgaactg
    25261 attatttatc gtcgccatcg acttcttcaa aatcagcatc aacgacatca tctgctccgc
    25321 cttgagctgc ttctgggttt tcttgagctt gttgttgtgc cgcttgttcg tatagtttaa
    25381 cagtcaagtt ttgaacgatt tcgttcaatg catcgcgttt agttttcatt tcttcgatgt
    25441 tgtttgcttc aacagcggct ttcaattcat cgcgagctgt ttctgctttt ttcacttctt
    25501 cttcgtccac tttgccttct aattctttca atgttttgtc cacagagaat agcaatgcat
    25561 ctacatcatt acgtaggtca acttcctctt tacgagcttt atctgcttct gcatttgctt
    25621 ctgcatcttt taccatacgt tcgatttctt cgtctgttag acctgaagaa gatttgatcg
    25681 tgattttttg ttctttttgt gtacctagat ctttcgcaga tacatttaca atcccgtttt
    25741 tatcaatatc gaatgttact tcgatttgtg gaataccacg aggagctgct ggaatatctg
    25801 tcaattggaa tcttcctaga gttttgttgt cagcagccat tgggcgttca ccttgtaata
    25861 catggatgtc tactgctggt tgattatctg ccgcagttga gaatacttgt gatttacttg
    25921 ttggaatcgt tgtattgcgg tcaatcaatt tagtgaacac tccacccatt gtttcgatac
    25981 ctaatgacaa tggtgtaacg tcaagtaaaa caacatcttt cacatcacca gtgatcacgc
    26041 caccttggat agcagcaccc atagcaacta cttcatcagg gttaactgat ttgtttggtt
    26101 cttttcctgt ttctttacgt actgcttcta caactgcagg gatacgagta gatccaccga
    26161 ctaaaataac ttcgtcgatt tctgattgtg ataaacctgc atcttttagc gcttgacgta
    26221 ctggtacttt tgtacgttct actaagtcag ctgttaattc atcaaatttt gcacgtgtca
    26281 atgtcatttc caaatgcaat ggtccagatt ctcctgctgt gataaatggc aagctgattt
    26341 gtgtgcttga tacgccagat aaatcttttt tcgctttttc agcagcgtct ttcaagcgtt
    26401 gtaaagccat tttgtcttga gacaagtcaa tgctgttttc ttttttgaat tctgctacca
    26461 tgtagtcgat gattttgtta tcaaagtcgt ccccacctag atggttgtcg ccagctgttg
    26521 acaatacatc aaagacaccg tctcctagtt caaggataga tacgtcaaaa gtaccgccac
    26581 caaggtcgaa tactaagatt ttttcgtcgc gatctgtttt atctaaacca taggcaagag
    26641 cagctgcagt tggttcattg acgatacgtt ctacttctag accagcgatc ttaccagcat
    26701 cttttgttgc ttgacgttgt gcatcattaa agtaagctgg cacagtgata actgcttttt
    26761 cgactttttc acctaaatag tcttctgcga atcctttgat atattgaagg atcattgctg
    26821 agatttcttg tggtgtatat gatttacctt ctacatctac tttgtaacct gcttcaccga
    26881 tatggcgttt gattgatgaa atcgtatttg ggtttgtcac agcttgacgt tttgcaactt
    26941 cccctacttg gatttctcca tttttgaatg atacaacaga aggtgttgta cggtttcctt
    27001 ctgggttagc gatgattttt gcttcgtttc cttccaatac tgctactgca gagttagtcg
    27061 tacctaagtc aataccgata attttactca taattaacgt ctccttcttt aattgaaagt
    27121 gtaagtttta tatccgcaca attattgtgc aacaatgacc atggttggtc ttaacacgcg
    27181 atcatgtaat ttgtagcctt cttgtagtac ttctacaatc gtatcggctg gtgtatcttc
    27241 agtcgctgga acagtttgta ctgcttgatg aagattagga tcaaaggctt ctcctttagc
    27301 agggattttt tcaattcctt cttcttccag tgcgttacgc aaactttcca agaccatttc
    27361 cacgcctttt ttcaaacctg ccccttgatc atctgacact tctgtggcta atgcacgttc
    27421 caggttgtca attgatggaa gtaatttttt ggctaaatct tgtgaacggt atttttgtaa
    27481 ttgctcacgc tcattttttc ctcgatttgc catatttgcg atttcagcac gagcccgcaa
    27541 gtatttatct tccatttctt ctaactcagc ttttaatttc gctgtttcga attcttccgc
    27601 ttcagcttct gaaatacccg aatcttctgc agcttcgaca tcgatttccg gttctggctg
    27661 agcatctgtc atttctttat ctagttcttc ttgattttct ttcacgatac agtcttcctt
    27721 tcattattca gtcagctgtt tgattgctct tactaagaaa gagagaacga tcagctgcaa
    27781 atagcttcgt tattcacatt acgagtttga caagtcaagc gaacggtagt aatcagcaag
    27841 tttagctgct agttctcttc gataaacatc gactagaccg aacatccgag aataaggcat
    27901 actagtaggc cctaacaagg ctattgtacc tcttccatga ccatctatct cgtaacttgc
    27961 ttgaatcata ctcatattct gcaataaatc attgcctaat tcagcaccaa tcttgatatg
    28021 aatattgcta tccatcggag tgatcatttg tgtaagtccg tctgagtctt tcataaaaga
    28081 aaacatcgat ttgaactgat caagatcttg acggggctca taatccaaga gattcatttg
    28141 tccactgaca taaaccttat cttcaaaaac atgaccaaga acggtgtcaa ataactgaga
    28201 catcccttct gtcgtttgga aatatttatg aagaatcatc ggaatctccg tacgaagttt
    28261 atggtacacc gtcatcagag gatctccgac tagacggtcg tttacaatct gtaccatttt
    28321 ttctagttcc tgacttccca tatattcggg aagagtgaac acttggcttt ctacattccc
    28381 catatctgtt acgacgatag caataatctg tcgattattc aagggtacga tacgaaagcc
    28441 agtcagtcgg cggtctttta tttcaggtcc caatgaaaaa gtcgtatagc ttgtcagctc
    28501 agataatatc tcagcagatt gcttaataat ctcattgatt tcatgaaatt ctctgcctag
    28561 agactgacga atcagcagca aatcatcttc tgctacgcga gcaggtttta acaaatgatc
    28621 cacgtaataa cgatagccta aagcagatgg aatccgccca gaagaagagt gagtcttcaa
    28681 cagcaatcct tcatcttcta atgctttcat atcattgcga atcgttgctg agctggcctt
    28741 gactccctca gacatcaatg ttttggaacc aacgggcacg ccactactcg tatagtgttg
    28801 gatgatcaga cgtaaaatgt cgttttgtcg ctttgttaac atcttcctca cctctcatta
    28861 gcactcatat attctaagtg ctaatccact tataaatata gcaagaagcc cttctcctgt
    28921 caagagaaag actccatttt ttagcactct aaacacaaga gtgctaattc taaataattg
    28981 atgtaaatcc agttatatca acgtttcaat agtcctttat tgtatttttg aacttttttt
    29041 atttaaattc agataaaaaa caaatattct ttaaactatt tttcaaacaa aaagcgctca
    29101 aacacattgt tccccaaaaa ggtccctctt ggtgtcaaat aaacacggtc ttcttcatta
    29161 acaagtaacc cttcttgctc taattccctt agcacatcac cgtacaccga ttcaattgtt
    29221 ttttgatagc gatcatagaa atgtttttta gtaatccctg tttttttctt agtcctaaga
    29281 acatttcttc ttctatttga ttttttcgtg tcaatttttc ttcttccaat accgggcgtt
    29341 catttgctcg taatgggcgt aaatagtgtt ggattggtcc tttgttgcgg taacgaatat
    29401 ctccaagata accgctagca ccagctccaa acccaaaata gtggtcattg ttccagtaca
    29461 tgaggttatg ttgagattca tgtccggaga gcccaaagtt acttatttca tattggtgac
    29521 gtccatgctt ttccattgct tcaatcgtct cttcaaacat tctggtttcc gtttcctgat
    29581 caggcagttc gagtcttcct tgtcgtaccc agttcatgaa cattgttttg ttttcgagga
    29641 tcaatgagta caaagaatag tgaggcagat ccaaagccaa agctttttcc aaagtatcca
    29701 gatatccttc tagtgtttgt cccggtaatg cataaatcaa atcgatgctt acattggtaa
    29761 aattttctgc ttctaaaaat tgcatagttt gatacacatc ttctgcggtg tgtttacgtc
    29821 caattttttt caataagcga ttatcaaatg tctgcactcc catggataaa cgattgacgc
    29881 catagttttt cattacttga agtttttcac gggtcaaatc acctggattc gcttctacag
    29941 taaactcatt accattttga aaaggcagga tctctctagc acctgataac agtcgatcaa
    30001 gttgtttagc agataaagaa gttggtgtcc cgccccctac gtaaagtgtt tctaaattcg
    30061 ctgtcggatg actttctagc attattttca tttcattcag cagcatttcc acatactcat
    30121 ctactggctg cccttctaaa aaaactttat taaaatcaca gtaatagcag atatgctcgc
    30181 aaaatgggat atgaatgtac gcagaaacct tgttttctgc gggatttatt gtttctatca
    30241 ttgaaattct ttctccttac gtcgaaaagt cgtgcctgtt ttcgaccttc ttaaaatcgc
    30301 gttcaagcac caactcattg aaataagccg catatttaga atcaaggaaa cctagctcta
    30361 aaaatgcttg cttattgtca tcggagctac acggtgcttt tacagcctct cgataaacgg
    30421 taatcgcaaa gctgaccttc ggcattaagt caaaatctgc aaaaatatga aaagctattt
    30481 tcacagattc ctccttaagt gctcagacca caacgctttg cttacaacct ctcatatacg
    30541 catactaaac gtatttggcg aacaaatcca ctaaaaaatc caagaatcga cttcttggat
    30601 gattttttct ttcattaaac tggttaccta gttatatatc tctagggttg ttttcatgtc
    30661 tgagtgcccg atatgattta tttttcgttt ctataattac tttttgcctt ccagtttctt
    30721 ttaatattgt actcaagcaa gtgggaattg gttcttttgt catccatgta tgcaaaatgt
    30781 tataatgctg gtaaacaaaa atgattacct gtcattttta tttagttcgt atttaattaa
    30841 gttgactatc tgtatactct gtctaaaact taagaattgt tgttttcgct gtcgctaccc
    30901 aattttaatg aatgtctgta ggttaaaact gttgtccttg ttatagatag taaaggagag
    30961 cttgaaaatg aaaactgcga ttacgtttct attagaggaa tatgccgatt gggaaggtgc
    31021 ttatattact agcacactaa accaaaatga gaaatggcaa aacaaaactg cttctatcca
    31081 atcagaggtc acttccattg gaggattaaa aacaaaaatc gattacttaa tcgaacaaat
    31141 acctgaaaaa gttgaccttt ttattatgat cggtggcaat tcatgggaca taaaaaatca
    31201 tcatttatat caaataatcg ataaattgtt aaaaacagac gtaccagtag ctgctatttg
    31261 tggggcagtt gattatttag ctcagagcgg attattgcaa ggttacaaac acaccggaaa
    31321 tgcgcaattt ccttggttag aatcggaaaa ttatcagaat aaagaagatt ttatagaaca
    31381 acaagctgtg aaagatcgta atttgattac tgcgaatgga acagctccta tagaattcac
    31441 agacttgatt cttcaagcag tccattttga aacagaagaa ataagagaaa aaacgattcg
    31501 tctatacaaa cttggattct atgattacta taaaaagtac ggagatcctt tctcctaatc
    31561 attctcttca attaaatact ccttatcaat agtgtgacaa gtaattttac tgatgattat
    31621 ttgtcacact ttttctgaca tttatcaaag aagatacact ctatttatat tcatagacaa
    31681 ggttttacgg attcaaaaat tcaggattat gctatactgg tattaaaaaa ataatgaggt
    31741 attttatatg aaaaagttag gttttatttt attgttggtc tctttattcc ttgtaggatg
    31801 tacgtctcct agtaaagaaa atagtgatcc atctgcgacc acagacaaaa gttcaatcag
    31861 acaaaccagt tcagctgaaa aatcaagtac tcagaaatca gcttctactg aaacgaatac
    31921 atcttcaaca agcagtaaag tctcagagcc caatacttct tctacatcta gtagtacagt
    31981 tgagacaaat atttcttctt caacaataga cacaacctcc tcacagtctt ctcagtcaat
    32041 agatccgtta gcaggatatt ctgatctaca aattgagtac gcacgtgttt ggctagctat
    32101 tagaggtaat acttttagag atacatcggg tgatttcgaa ttacatgtta ttcattatcc
    32161 tgcaggaaca cctatcgccc cttatgatgc agggagtgca gtctatccga aagatgtggt
    32221 tatgctcact gggaaataca gttaccaggg agttttagtg tattcaagta accatgacgg
    32281 gacaatcact agttatccag ttccttcaca ttggcaaatg cctgcagatc aaacatctta
    32341 tccagcgttc attagagaaa caactcaaga aatcattgat aatgcatctg tagtagctat
    32401 tcctacagga aatcccaatg acgtgaaaca gttaatcgat gtgacagtta tagataatta
    32461 gactttctaa tatgttatac aaaaagaagc tgacagc
//
LOCUS       DAZKCH010000026        31067 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000026 DAZKCH010000000
VERSION     DAZKCH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.026"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..329)
                     /locus_tag="ACG84X_001221"
     CDS             complement(<1..329)
                     /locus_tag="ACG84X_001221"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127110.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(343..600)
                     /locus_tag="ACG84X_001222"
     CDS             complement(343..600)
                     /locus_tag="ACG84X_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127111.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(795..1337)
                     /locus_tag="ACG84X_001223"
     CDS             complement(795..1337)
                     /locus_tag="ACG84X_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFP9127112.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(1358..2449)
                     /locus_tag="ACG84X_001224"
     CDS             complement(1358..2449)
                     /locus_tag="ACG84X_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFP9127113.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(2457..4667)
                     /locus_tag="ACG84X_001225"
     CDS             complement(2457..4667)
                     /locus_tag="ACG84X_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFP9127114.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(4683..7211)
                     /locus_tag="ACG84X_001226"
     CDS             complement(4683..7211)
                     /locus_tag="ACG84X_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9127115.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(7263..7673)
                     /locus_tag="ACG84X_001227"
     CDS             complement(7263..7673)
                     /locus_tag="ACG84X_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFP9127116.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(7686..7904)
                     /locus_tag="ACG84X_001228"
     CDS             complement(7686..7904)
                     /locus_tag="ACG84X_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpD family membrane protein"
                     /protein_id="HFP9127117.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(7901..8893)
                     /locus_tag="ACG84X_001229"
     CDS             complement(7901..8893)
                     /locus_tag="ACG84X_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFP9127118.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(8972..9883)
                     /locus_tag="ACG84X_001230"
     CDS             complement(8972..9883)
                     /locus_tag="ACG84X_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFP9127119.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(9902..10246)
                     /locus_tag="ACG84X_001231"
     CDS             complement(9902..10246)
                     /locus_tag="ACG84X_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127120.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(10266..10544)
                     /locus_tag="ACG84X_001232"
     CDS             complement(10266..10544)
                     /locus_tag="ACG84X_001232"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127121.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVMQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            complement(10903..11403)
                     /locus_tag="ACG84X_001233"
     CDS             complement(10903..11403)
                     /locus_tag="ACG84X_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127122.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(11404..11949)
                     /locus_tag="ACG84X_001234"
     CDS             complement(11404..11949)
                     /locus_tag="ACG84X_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127123.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(11946..13202)
                     /locus_tag="ACG84X_001235"
     CDS             complement(11946..13202)
                     /locus_tag="ACG84X_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFP9127124.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(13563..13874)
                     /locus_tag="ACG84X_001236"
     CDS             complement(13563..13874)
                     /locus_tag="ACG84X_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127125.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(13897..15372)
                     /locus_tag="ACG84X_001237"
     CDS             complement(13897..15372)
                     /locus_tag="ACG84X_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HFP9127126.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(15821..16273)
                     /locus_tag="ACG84X_001238"
     CDS             complement(15821..16273)
                     /locus_tag="ACG84X_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127127.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(16275..16640)
                     /locus_tag="ACG84X_001239"
     CDS             complement(16275..16640)
                     /locus_tag="ACG84X_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127128.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(16739..21022)
                     /locus_tag="ACG84X_001240"
     CDS             complement(16739..21022)
                     /locus_tag="ACG84X_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HFP9127129.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(21169..21408)
                     /locus_tag="ACG84X_001241"
     CDS             complement(21169..21408)
                     /locus_tag="ACG84X_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127130.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(21498..21740)
                     /locus_tag="ACG84X_001242"
                     /pseudo
     CDS             complement(21498..21740)
                     /locus_tag="ACG84X_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21853..22089)
                     /locus_tag="ACG84X_001243"
     CDS             complement(21853..22089)
                     /locus_tag="ACG84X_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127131.1"
                     /translation="MFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTELKDKN
                     NVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            22267..23226
                     /locus_tag="ACG84X_001244"
     CDS             22267..23226
                     /locus_tag="ACG84X_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9127132.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            23396..24076
                     /locus_tag="ACG84X_001245"
     CDS             23396..24076
                     /locus_tag="ACG84X_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFP9127133.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            24166..25200
                     /locus_tag="ACG84X_001246"
     CDS             24166..25200
                     /locus_tag="ACG84X_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFP9127134.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            25214..25549
                     /locus_tag="ACG84X_001247"
     CDS             25214..25549
                     /locus_tag="ACG84X_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127135.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            25533..28013
                     /locus_tag="ACG84X_001248"
     CDS             25533..28013
                     /locus_tag="ACG84X_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127136.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            28069..29628
                     /locus_tag="ACG84X_001249"
     CDS             28069..29628
                     /locus_tag="ACG84X_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127137.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQISYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            29625..30989
                     /locus_tag="ACG84X_001250"
     CDS             29625..30989
                     /locus_tag="ACG84X_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFP9127138.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
BASE COUNT         9467 a         6418 c         5070 g        10112 t
ORIGIN      
        1 gaattcattc cccaaaggcc ttttaagatt gatacagcag tccgttcact tcttttagac
       61 ttgtcataca agtcttttaa atgatcccat atcagactag tttgtctatc tagcttcaat
      121 ccattaaacg ctaatgaacg gttcattttt tctattactt tagataaagc tacagaaatt
      181 tttatacctt cacaacgcgc atcttggatt tcaataatag tatcatcaat tagtttttga
      241 atttcttgcc tatcaacata ttcaatctta gaaagagaat cttttaaagc tactaatgat
      301 tcaacgattt cttttttctc ttcagacatt ttcttcctcc ttctagtgac ccgtaaagcc
      361 atgtagagca gagtccattg aaccagtaat tacactatct acaacgccat tccaatttac
      421 tctacatttt ccatttttca gatttgtcgg tccatacgga tagccttttt gacattcaat
      481 gttcggatta taccagatag gattatacca ttcagccgca gaagcagatt cagtcgatac
      541 aaacaatccc acaccaacaa atccaataca catcacacta tagccaatta gttttttcat
      601 ctcgtatcca tctcctaaaa aatagaatag ttcttatagt tattcataag acatattttt
      661 tccgtttttg ttttatcctt tctgtcctat aacaactttt ttcaagtaaa gaatgacata
      721 gtttttctta aaaaaacagt ctgttttttt ctatttcttc ggtgtataat aaatatgagt
      781 gttcattttt tattttaata cgcactccgt acataataaa tcttgatcgc atcaatcttt
      841 tgagcttctt gatctacttt caattgaagt aatacaaatt gagtaacctt attcattgtt
      901 tcttctccaa ataacaaata ttgatccgga ttctctatat cttgtgtcac ctggtaaagt
      961 ttcccagttg ttttcatttg tacatgcggg tctacatcaa tactattgtc tttaatacaa
     1021 cgatctgtca tatagtccct cacagcttga ttgcgtttat aaacatctgt gaaattactc
     1081 cattttctag caaaatcttt taagaaattt tttgtcattt catctatttg catttgttgc
     1141 gctgtctcgt cttctaatga accaatttga ctgttacttt cagtactttg aagagttcca
     1201 cttgtttctt ttactgcttc gattgtttct tctgtcgttc tcaattgtgt tttttgtttt
     1261 tcagaagaaa accaatgaca accagtaaga cctatcaaac ataaccaact aaatactaaa
     1321 attatccctt ttttcacgtt tctagtcact gcctttctta tttcacctta cgaaccagac
     1381 tacgaatttt tgtttgattg tacgtgcgtt gataccgagc cataatccgt ccttgctcgg
     1441 cattctgttc cacactagag aaatgttgtc cgccatatga aacatctgtt ataattccgg
     1501 tgtgaccata gattccagga gacaatgcac cacctgcttg ccaattcacc acatctcctg
     1561 cttgtaaatc acttggtttt gggttcatga ttacttgcca accataggtt gtccagttat
     1621 aatcttcccc tattaacatc gcaaacatgt gtccagaacc cattaactgt gggccaccta
     1681 attgagatac ataccatgcc gtaccaccat aacattcccc attatttacg gatcgtccaa
     1741 tgatccgatc caaaaccttc gcattgcctt tactttttcc tgcaataagc gaagtttttt
     1801 ttgttggtag gctattccaa tgcttgatcg caaaagtatc atattccgtt aagttatagg
     1861 acgttatgat actcattgct cctcgataat acggactccc ttcggtaata cctgctgccg
     1921 catagcctcc acgacctaga atcaataaac aacttccagg atctttattg cccacacatt
     1981 gattaaagtt gctttggctc gccaccataa agccataata gtcataacaa gcttttaagt
     2041 tcggaaactt catatagaaa ccaccttcag aaccaccaat tccacgtgca gaaccttgtg
     2101 ggtagggaca accaggaaac caggtaatcc caaaaaagtt cgtatcgttt cttccagatt
     2161 gtgactgtcc ataagctgat tcatagccta attgagaaag aatcacactc ggtaataact
     2221 gatactttac agctgcacca actgctgctt gcgcatgttc atctgtgatt ggaccacgtc
     2281 ctttaatctc tgaaaaaatc ggtaatcctt cggtatattc cccattaaaa gcgacagcta
     2341 gacctgtagc ttctcctcca tgctcagaaa gttctcctga aaaaaagaat ggcaatagaa
     2401 aaaagggaag aataaagaaa agaagacaac ctagacaccc tttcttcatt tcttcctcat
     2461 cctttcttcg ataatggttt ttggactgtt cgtccttttg gtaaagtaaa atcagttcct
     2521 ggttttgcgt ccaaaatcgg cagtgtttta ggatcctttt ctattttttc cgattgctct
     2581 gttggcttat ctaaagaaga aaatgcaggt tgtaacgatt ttggtgcgga aatcgacggt
     2641 ttactttcag acgaacgttg ccccggttgt tgcacagaac gatttcctga tagagtggct
     2701 accgacgaat taggaacaga gtattggttc aataactgct gcattgctgg ataactccca
     2761 tttttcgcct gatttttcac ttggcgaatc tgttgtgaaa gagaaccagc agctgttaat
     2821 tgtggcacgg gtacttttcc agaaggcaac ggaatcgatt gaccaacaaa agcgatacct
     2881 ttatttaaca atggttttct ttgattattc ccttgttgct tactcaattg tgccaatgat
     2941 tgtacctgtt gttttggtct tactgaattc atggacgaat ttggaatcaa accatttgaa
     3001 agaccagaat tccactctgt tttcgatttg gtagaagaca tttcaggctc taccccatga
     3061 taacgaacat gacgaccact ataaggcaag gcttgatttg aacgcccacc tagttcaaag
     3121 ggattaacca cttgcctccc ttttaccgat tcttgtggtg tacgtttttg ttgaaacttt
     3181 tgaaatccat gtatcgctgc agaagcgagt ggattcgttg ctcgatacac attccctgct
     3241 aatcctgcac ctttgattgc caaattttgt ccagcagttg atagttgacc aggcagttgt
     3301 ttcatttgag acaaagaatg acttgctatg tttttcgtgt tgtttatagt ttgatctgca
     3361 gctcctaacc ctagtttctt taataaatct ttccgtttta caatgagtaa aattgatagg
     3421 agtgctttga caaacatatt tcctaaaaaa ccaaaaacag tattcattgg aattaaatcg
     3481 tctactatgt tatagatcaa aaatgccacc aaaataatca cactgtaaaa agatttttga
     3541 aacatcaagc ccaaaaagga ctttaaggta ttcatgagca tataatcaaa tactggaaca
     3601 aaagaagcga gtaatgaaaa aggaatcaca agtaataaac acaacaccaa catttgaaag
     3661 ataaaacgaa tcatgccaat cactacaagt ggtaatccaa tacttagatt aagcaatggc
     3721 accatagaac caacgactgc tttataaaca gctttagttg gttgaatata gacacgataa
     3781 gccttctttt tccctctatc ttctcctgca gcagtggtca cttttgtctc aatatcagat
     3841 aattcttcac ttgacgcttc cttggctaga aattcttgtg gttcaatctc tgcttgatac
     3901 aattcttcta aatttgttgt cccataattt aacaatatat acggatcaac aacagccgct
     3961 ttataataaa gttggcgcac tttttgaatg gcttcctttt gtgtcgttgg cactaaaaca
     4021 ccattgacat cttttgtcgc caattcatct agactatttg tagcagaaaa aataaagcct
     4081 tctacctcca cggacaaatc atttaaccct ttggtaaaag cttctccttt actaggtacg
     4141 ttactaccat agccaaacca aaccattgaa aaaatgacaa cgaagagaaa tcgaataaac
     4201 accatttttg cgtaatgttt ccctctaaat atacgaagag taaatagata taacacatac
     4261 aagacgacaa tccccgcacc aataggatcg tatatttttg aataaatagt atccgaaaaa
     4321 gtgaaaaact ggtgaattaa ctcgttcatt gcagctcctt catagagctt ctcaatgaca
     4381 aaatcaaggc cttgccaaat caatttactt aaactaaaga acatattcgt catcattttt
     4441 agaaaatctg tgccatttgc cccaaataac attttgccta atgaaaattc actatcagat
     4501 aaataagaag aaaaggtatc aatatgaaat ttcccaatct catagatcga ttgatccacc
     4561 tgcttttctg ccgcatacac caatccacca acaaaaagca gtccgaatcc aatcgttaaa
     4621 aaaaacaaaa cgcaccattt cttttcctta tgctttatat aagccattgt ttcacctcat
     4681 ttctattgca tgattaacgt atcctgttct tctacttgag agtgacttgt tttttccgtt
     4741 gtttgtaatg cagcggtcat ttcttcaaac aaactgtgta cattgagttt tcctacacgt
     4801 ccatagggat ctaacatcca acactgtcct ttaatcatgt ggctcatttc agctaagttc
     4861 gcttcattta cttccaaacg taaatgattc aaaatctttt ctcgctcact gtcttcatca
     4921 aaagcaaaga cgacaccaaa attccctttt tctttatctg aacctaagtc accaataaat
     4981 tgtgtatcta acactaattg attcatctgg gaacgcccca cacgtgccat tgctgcaata
     5041 atactacgtc ctgcgttcga attattaaat acccatgctt ctgtaaaata aatcgctgtt
     5101 ttcttactac tatctcgttt tccaaacatt tcacaaaaac gacctaaact aatcatcaaa
     5161 cacaaagact ttcgatccgc atctgtatat agttctggtc ggacattgtc atttggtaat
     5221 ttcaaatctt ggatctctaa aatcgttgtt ttggcattaa agtctaatcc cgggttttct
     5281 ccataagaaa atcctaaacg taaaatcgaa tcttctaccg tcaagcgtaa aaactcacca
     5341 tattctcgaa cctctttttg ttccatttgt tctaaatagt cgaccacatg catcaagcca
     5401 acttgttgtc cggcttcttt ttgaactaaa acttcttgga ttccctttaa taccgcccct
     5461 tttaaaaggt gattggtacc taacggactt aactcatcaa tcatatcctg ggctacttgt
     5521 ttcgcatcta ctcgggataa acaaacaatt ggatctaata caccataatt acggggattt
     5581 gtagcatcta acgtgacata actcattttt tgcaaatgtt ctacaaacaa agggtaatgt
     5641 ttctgataat acgggtcttg aatgagtttc gtaaaccatt tgcgcttttc tcctttggga
     5701 tccacaaata aactttgtac attcataaac gaactataca aaaagagcaa gccaactaaa
     5761 aaggtcttcc ctttaccggt ttttccagtt actgctacat gaggcgcatc aaacaacgca
     5821 cctttgattc cttccgcaat ggctagaaga ttcaaaaaga caaaacgatt tgacgcataa
     5881 attaattctt ctaatggtgt tttttctcct cgagaaccac catcccctaa tgtatcttgc
     5941 cgaccaatat accagccgga ttccatacct aattctgata ctgctgaaaa caaccattcg
     6001 ccaactgctt ctacagttgt tcggtgcttc caatgtaact gccgtcccaa tggttgccct
     6061 aataaacatt tatagaacaa ttctcgttga tcattttttg cacggtggat atggataatc
     6121 gtatgaagtt gttgaataac cgttgcacta ttttgacgaa cttcttcaac cgtttgaccg
     6181 tatacaataa aacatgcgat ccaatcgacg acaggttgcc cattatctac tcgttgcttt
     6241 aaatgtttta ctaatcctcg aacagttaat aagcgttcac taggttcttc atcattttga
     6301 accaattcct tatgctctgt tttgaaccgt tccgatagcc aattcagttt taaaccaata
     6361 cctccctgtc ctttcaagcg tggatagtga attttcattc gcaattctgc tgggaaagaa
     6421 agatcctgag caaattgaaa tagatcacaa tttctcatat tttcaggtgt ttccccaata
     6481 ggcaacaatg ctaaataact actccctaac tcatcttcta attgaagaag gcctttatgt
     6541 tccttcggta tacgtacata cgttccttga ttgtctttca gtacttccca attattttgt
     6601 tcttctactt tgtgagccat tcctcgaata tattgcagac gattgagata caacagctct
     6661 ttttttacta agggacgaat agaaaagcta taaagtaatt gtgtcacttc ttttacataa
     6721 ggatcacttt cagaaaacaa agtttccaaa tcatctactt ctaatccaaa taagcgtgct
     6781 aaacttcctg ctaaatctaa ccagattaga tttattacat catgaaaact ctccaccgtt
     6841 gctttttctt tgactttgat tcctaaaata aatgaaggac gatagacttg accttctcgt
     6901 tccaacaatg tcactgtttc ttttgcataa tacgcaccaa ttgcttgact atcgggagaa
     6961 aatccctttc ctaatgtgtc aaacttcgtc cgtaaattca ttgttcgtgg atacatcacc
     7021 aactccacat cttcataatc tgctaaaagc aacagtaaac gagccatcat ttcttttatt
     7081 tcctgtgtct tttttggtgt gttttttgaa attgttcgtg gaaaaacatg atagtaggcc
     7141 cagatacaat cctctccatt taacaaacaa tttttcttga atgcttttac tggttctttt
     7201 acaagcacca atgaatttca cctcccaata aaaaaggaac aaccagttga ttgtcccttt
     7261 ttctaatcct ctaaataaac atacttattc acaaaaagta attcttccaa tgcattgttt
     7321 gataccttgt cccagttata atacacacaa tcaccattca tcatacgaat catataacaa
     7381 aaccaatccc ataaataaaa atgcactttt tttccatcag gttttagttt tgccagtgct
     7441 aacacacata aataggggag tcctatataa aaaacaactc ctgctggtgg aaaaaaagaa
     7501 atgacccaac caataaatga acgtaaaaat aaatattcaa agattacgac caacaaaaaa
     7561 gttgctgcat tgactaatgc aactggaaat ggaagacgcc aattgcttgt aatctgttgt
     7621 acgcgataag gttccgcata aacaatcgaa taatcataag gttcccaatc cacttcacta
     7681 tcctcctaat ccataaataa tttttcaatg attttaccaa acgcatcaaa tacacgtgtt
     7741 ggatcattta agaagaaata aactgcggca cctgctgcga tagatattaa tgcatttcct
     7801 acttttgatt tcataaaatt tcgcaatccc agataaacaa ccaccattat taaaaaatag
     7861 ccaccttgcg ttaatataaa atctacaatt cccttcagtg tcatttccgt tcttctcctt
     7921 tcctatccaa ccaattatgt gttaattttt caacataata ctgatttgtt tttttcgtaa
     7981 tgacaatcgt catttgttct ttttgtaaaa gtgacgtatc accatctcga aagacgaccg
     8041 ttgcttttac aataaaaggt tttttcgttt ctttataacg caatactttc atctctactt
     8101 gatcaacttt agctgtttga ttgagtcctt caggttcttt catcatgtat gacatatctt
     8161 ttgcattgtt tttcgcatac ttatctaaga aatcttccac aaatccttca acatctttcg
     8221 cttccgacgc atcaaccgtt tcgtataatg tgtcatcata agtaatcatt cgttgttttt
     8281 ctgtattctt tggtagtgcc gtaaaataag gataagcaat aatacgacag cccttgtttg
     8341 aaatagaaaa gggaagattg agtacttgtg tgattgtcac acttgtttct ttcttactct
     8401 ctggattcat cgagcgaata tcataagtta ctttataact agcagttgga atggtttcaa
     8461 tttcttttaa tccaataaac gaagcagcag ttaattttcg aacacctgaa acacttcctg
     8521 gttcttgaat aaagttttgt gcataaaact ctttttttaa tgtttcttga cgttgttgtt
     8581 cttgttcatg attatcgaat gtattcatat acaaagcaac aaaacgattc ataaaggatt
     8641 caatttcagg tgtgtacgtt aattctgacc gactttgtac ttctttcttt tgtaattgtt
     8701 ggatttcatc tttcaaaaac gacacttgaa ccttcgtttt catggattga aaaaatgcca
     8761 agccccctga aaaacaaaga aataaaacca aacaccaaat ccatttcact gctttttttg
     8821 aatggatttt cttttgcttc ggtactttct ctgtataaac tttttctttc cgccgtagtt
     8881 gtcgtttttt cataagctac tccttctagt atgtttttac tagtacgtac gattgacaac
     8941 gataagcttg tttttctgaa aaatagtcca ttcaattacc ctcattttct attccttttc
     9001 tctttctttt atatccaaca aatccagcaa tacttgtcaa cactcctcct agaacagaaa
     9061 gtgcaacatg tatttcttca ccagtctttg gtaagacttt tgtttttcca tctgctgttt
     9121 tgatttcaat attgccactt ggaagtttct ttacaggaat cgacaaatcc tttaccaaat
     9181 tcccttcact atcttggatt aatggaatac catcttttac accaacaatt gtttgatcac
     9241 ctgctacttt taatggggtg gttggtgttg gaatatgggt caattcctct acattactag
     9301 tgacaatcgg tacactcatt ccttgagaag tattcgtcgt aatttcaccg cttggggtta
     9361 ccgatactgt gacttctttt gctggaacaa taggtttatt ttcttttgga attgcttctg
     9421 atttttcaac aggttgtttc ggttcttctt tttgttcttc actggtagac gacatcgttg
     9481 gctgttccgt acttgacgaa tcagtattct tttcagaaga actggttgtt cctgattgtt
     9541 ccggagttgt gactatactt gaatccgttg ttgttgaact atgcacacct tcttcttcga
     9601 tcgaatcagt cggtaaagtt gattcaggaa actctggttc tggtgtcact ggctcttttt
     9661 caggtttctc tgactgcaat tgttcaggtt ctgctggttt ttccgttgtt cctccattta
     9721 gctctgtctc aacatctggt aatccttccc ctggcaatgt ttctacaatt tctgacttag
     9781 gtgtttctac agtttcatct gcataaacca atgaactccc taattgaaac gaaaataatg
     9841 aaattcctag tgttgttacg actgctaatg ttgttttttt catgattatt cctccaattt
     9901 tttatgcaat tcgtgttttg ttcatagacg ccgcactaat attatctgaa cgataaaaga
     9961 actcccgtcc gttttcttct aacccaacat atggattatt tttgaataat tgaatcaata
    10021 gttcactggt gttgtatttt ggatagtttg caaaaaaata atactgtgct tgtcgcccat
    10081 ccgaaaattc aacaagtaat tcataacgat accgcttcaa tccttttcgt tgttttaaag
    10141 gatctctata ccaacttgtc catcgttcca ttcgtggata gagatagaca cgatacacat
    10201 agaacaatgc cataccacat accaccaaaa ataataatcg ccacataaaa attccccctt
    10261 ttcttctacc tttcttgaat catcgaacat tcataccctc tatagagatt tgaaaaatcc
    10321 atcatcaatt gttcatataa acgttgttgc aaatagcgat tgtttcgaat acataattct
    10381 tcatagccat caatcacttg atcttctttt tcatagcatc ttgtagctct atgacgctca
    10441 gcttgcatga cataaccaaa ctctgcacca tatcgttcta ctgttaataa ctgttgacta
    10501 cgcaataatg caatataaca atcacaaaaa tgttcaaccg acatttgatt tttctcacgt
    10561 ttgtgaaata ggtattcttt agaaagcaca ttattcgtta aacaatctga taaatagcga
    10621 taatctggcg gtcggttatt ttcatctgtg aatttttccc ataataaact gatttttatt
    10681 cgttcagcgg ctagatagtc ttgttcgcgt ggataaaatt catcaatcgc acaaagtttt
    10741 ttatcacctg aataaacaaa tccatataat gcgaaacgaa ctcttccttt tcaattggct
    10801 ctcctaaaaa ttccagtgac ataccatctt ctccttccta aaaaaaataa aaaagcagaa
    10861 accgatttgg cttctacttt tctttccttt tatagctctt ttttacggaa gaatccgcaa
    10921 atgacatttt ttcaaaaaat caatcggcac aagttcacga aaacttggag caattttgga
    10981 tagaatcact tccccatctt gtaaaataca atcataaaaa tcatcagtta cttgatactt
    11041 acgcttctta caataattga taaaatagta gcgatcattt tctatttcca ttcgttgttc
    11101 tactaagcgc atacgaacat catcatagaa ataagccaca aatcgccctt caagttcatg
    11161 tttttcaatg ggatactctt ctggtaacaa tctatttttt cgtcgtttat acattgctgg
    11221 ataccttaga agaagttcat ctaaacgtct gtcagtatat ggtaactgac gaatcaacga
    11281 ttctaatcgt tctttataca gatagaataa ttggcgcaag caatagtgta ccgcctctgg
    11341 attttctaat actgttggat cacgtgacca atacgcacca acataaatca taattttttt
    11401 catttagaca atcacaccag caatactaat gaccgatcca caataggtag aacaagtggc
    11461 atagcgacca atttcctcta attctatctc aatctcttct aaagaaagat atgtctgttc
    11521 ttctgttggc tggcgactca tttcccaagt gacagtcacc aatgaaattt cttccataag
    11581 aggtttttcg ctgctaagtg ctgccacaca gttttcatat atcttcattt tatcgcagcc
    11641 ttttttaacc gctaaaatcg caggtattgg caatgaaaat cgataaaagc gaatgaattc
    11701 tagccttcct ttccttcggc taaattccaa ctcttcgagt tcttgttcgt atcccttacg
    11761 aacttctaat aagcgtgcaa tttcttgcca gttctctttt tcctgataac gtccagcttt
    11821 taccgcttgt tcaatataag gaactcgaaa acgaaaataa gacaaatcaa ccatcttttc
    11881 atttaatgct tcgattgcag cctttaaatc caacaggcgc agccattctg ttgtcgtata
    11941 tgcattcatg caattttccc tcctgacgtt cccatccatt ctagatagtt ttgttgctcg
    12001 tcatttagtt cggcattatc aatcccttct tgtacaaagt ctcttcctaa aatacgatct
    12061 gcttcttgta acaactttaa tgtcggagct acttgtttca aaaaccagcg ttctgaacga
    12121 tctaatgaga atttttctgg ctttactgta aaatccaatt cttccatcga acgaaataat
    12181 tttgcccatc gtttatcaac aatccgtgca tcactttcca gtctatccca aacaataagt
    12241 tttgcattaa ttaaaccaac gccaatctct cctaaacgtt tcggtgaatc acctaaaata
    12301 aatgcttcta ctgcttgtgt tgctttctca ttggctaacc gtaactcata tcgattataa
    12361 ataccatatt tcgttaatgc ttctaattct gaaatttttt ctcggttcgc aatttcaaaa
    12421 cgtttctcat aaaaattaaa aaagagagga ctctttcgcg atccaaaata caaagataat
    12481 ccttcacttc gaaaatagcc atcatctaaa aaacaaccgc caatattctg gaatctctta
    12541 aagtccattt ctaataaacc tgctttttgt ttttctagta attcaaagag atcgaaatgt
    12601 tcttccgttt ccaatcccca aagttcatct aacgcaatat cgaatcggct acattgcaca
    12661 cgtgtataac cagcttccaa ctttccttga tttttccaaa tggaatatag ccatgttcgc
    12721 caatctgttt gttgttcacg catgacttcc tcatattccc ggcaaccttg tcctgaaaat
    12781 tgcacaagta cattttctgt tacagttcgt tttgaatgcc agaacaccca gatattccca
    12841 cgaacagaaa gacagtcaaa aagatacaag cccgttggac gtgtttcaaa ttctgtcaga
    12901 tccattcgta atacacgttg aatcactgtt ttgtagtctg tcccaaaaaa ggaaagacgc
    12961 aaataatcaa tcattgctcg aagatctatt ccgcttttca tatacaatcg aaagcgttcc
    13021 ttgattcgtt gttcaaaatc ctctgggatt tttcttttcc cttgttccat ctttctaatg
    13081 taatcttttg agcagcccat caattgcgca aatcttgctt gtgatagcgg ctttttatct
    13141 ccacttatat tatgaattgc acttaacttc tttctgtagc tttttagctc aatcggtgtc
    13201 attttctcgc tccttttata aaataacaaa atcgattttt tttaaccctt tagaaacacc
    13261 gatatatcaa ctagtccccc tcgttttttg ggaaaagtag tacaactgct gaccttagat
    13321 aatcacttga tacaaaaggg tttataaaac ttttttctat gtgttatgtt atttctgccc
    13381 cccatattat atatcggggg gctttacaca aagaggccgt gcgcaagcgc acgacctctt
    13441 tgtgagctgc acacgctgct agcgagtgcg cattataggc ccatgcttcg cagccttaat
    13501 gcgcaccgcc aggcagagtg cggctaccag actacgtcta gagccctccc gatagataat
    13561 aactacaaaa ttaaatgatc taattttgtt atttcactat atttttcagg agaaaaaacg
    13621 cgataaattg acaaagttaa atcctcttct aaatctactc gataatgata caatcgagtc
    13681 aatcgttcta tatctttttt cgttagcaat acttgattaa taacttttcc tgtaaaaaca
    13741 cgttctttgc gcaaaaagcg gtaatcagtt acttgttcaa tacgattcaa ccaatcataa
    13801 aacgttctgg aagaaagaga aggattaatc attcgtattg ctgtagctac tctataataa
    13861 caactctctg ccatttaact tcacctcctt agttgattac aaaatatgcg catcagaaaa
    13921 acttgttcct tttggatctt ttgctaaata catttggcgc tctagttgtt cttgtaacaa
    13981 ctgattatca tctcccatcg tttgatcttg actatcctct tttactgtaa aatcatagac
    14041 aatcatttca gtaaatttct caaattcttt gataaagtga taatctttgt aaacaaatgg
    14101 cgcaaaaaac tctacaggta catcaaatcc tggaaaagca tatccacgac caggttgatc
    14161 tttgttgtaa aatggcttat ttttaaaatc ttctccaaaa gtcattaaat aaccaatggg
    14221 agacaatcga ccaacagaaa tacggaatgt taaattatcc cgaacaccac ttggaaaata
    14281 ttctgcatct ggtcgttgca ttgctaaaat aatgtacatc cctgcttgac gaccctttaa
    14341 tactaatggc tgaatcaatt tatcgactct atttctcgct tccatatcca acgaaccata
    14401 aaaagctgcc cattcatcaa aaaagataaa atgcggtggt aacccataat aagcataatt
    14461 tttccctggt tcatatttag gatctttcat ggttttcata taggcatacc gttgattcat
    14521 ttcttttaat gcatttcgta aacaaataat catttcttca tttattttgt aaaacacatg
    14581 tcctttgaat acatcgacgt cacctaatgc tgctaaatct gccgcttttc catcgcaaat
    14641 atctactgtc ccaacactta aacaagcttg aattaaagaa tacaataaat aggttttccc
    14701 accaccgatt gcaccagcaa tcaacatatt tggtgattga tcatataccc aatccaaagt
    14761 tttcattaaa tgaatacgtc cattttctgc tatacattga tcaataggaa tccgaccaga
    14821 atctgaaagg aatacataat tgattcgggc tttttctcgt tcttcacgaa ttaaatcacg
    14881 caaaaatact tcagataaca aatgacccat ttttaaaaat cgttcgtgaa aacgcccacc
    14941 atctaaagga aaagaaacca ctaattcttg tttcttttga taaaaataaa cttttggtaa
    15001 tctcattttt tcccttgttt gtttctcact aacttgtttc tttgtataaa caaaccgatt
    15061 gtcaattaac attcgaacaa gtaactgacg ccaataaaca gaggcaaaat atccttcttt
    15121 tagtcgcgac caatgcatca accctaaaat taacccacta accagcaaca aatacaacac
    15181 aatacttatt ccaggaataa gatacatttg ccaattcgaa aacgtactta aacgtggata
    15241 aaatactttc caactaaacc aacctaacag aatcaaaaat ggaaacaaaa agaaaccata
    15301 atagcaaaac cataaataac gattgaaata gcgaattcgc cgaccacgat acttgaaaaa
    15361 atgagctttc aattgtcaca ttcctccttt ctgtttttac ttttcctgtg ctaaaaactt
    15421 ttgacaaaaa gcaactaata caggaatatc acatttagta aaaaaacata atcgaaaaag
    15481 atttaatcga tttttataag ggtgtgcaca catattacat attcgtacta tacgaatcca
    15541 aatcacttcc tgatgatctt gtttccactg gtacggtaat gaaaaacgaa caagatcacg
    15601 taaaaacata cactgcccaa taaccgcaca aatatatgca tttgtttgta caaaaatcgt
    15661 tggattgtct ccaaaatact caatcaattg ttggatattt tgataacaag cacaatctct
    15721 caaagtattt gattggtttt atctgaattc aaaatctccc cttccttcta tcttagataa
    15781 aaagaatagg aagactcctt cctattcttt caaaaaaacc ttattttttc tctttttcct
    15841 tagaatcaac acttggttgt ttttgatcta aacctttttc ttgtgattgt ttcatattag
    15901 gattatttgt tggagcttct actttctcta atcctttcgc ataaatcact aaatctgaat
    15961 attcacgatt gccatcttgt gctggaatat ataccacatg atattctgga tcaattaatt
    16021 tcacaggatc acgtcgttta aaaccagtca aatctacatc tgctggaaat ttaactcgtc
    16081 gtgcaatctt tggttcatct ggatttccaa aaactaattg tgctcgctgt gatcgaattt
    16141 ctcccgtata atcgcctgtt tcattatcaa atacacgatc agactcttct aatgcgccaa
    16201 agcgtacggc tcctaaacaa gtttcatcta atgcttctgt aatgtcataa ttatttggaa
    16261 attttaatcc catcttacaa aacctcccca atttttacac cagttaaaaa gacaccaaca
    16321 tcttgatagc cagttgttcg acgctctgtt tgtcccatat catttgtttc acgactattc
    16381 actcgttctt tacgaaaaac aaaataagct tcttcaaatg aaatacgcac ctctttttct
    16441 ggtaatcgta atcttttatc ctcttcagct gtgagataaa caaaaaaagc aggctgttct
    16501 tctcgcgaac actctgcttg taattgaaca tatcgcccag acacaccatt aatttccttt
    16561 ggtggattag gttcccgtga acccaataaa aatacttgac ctaaaaactc tttcttcata
    16621 cgcaatgctt tttctgccat aaagtttttc ctcctcttaa aaaccaaaat aaattctaaa
    16681 tatttctaca ttacaatcaa acaagcggtt aaaaatccta accgcttgtt cctcatgact
    16741 aatctttggc tttacgtact ttataaagtg ttatacctaa agcaatgact aatactacta
    16801 atccaagaac cataagtata ctacttgttt gttcacctgt ttttggcaac attggtacaa
    16861 cagtagctgg tttaacccgt tgttctggtt tcactggttg cggtggtttt ggcgcttcca
    16921 caatttgaac cgtttgatct ttgtttgtta gatctacatt gtgtttcgcc acttcttcaa
    16981 acgtttcttt ctcatcttcc gttttcgctt ggagccattc cgcaaaactc aagccttttc
    17041 ctgcaagatt gcgaccgtcc actaagaatt caaataagaa ttccatcatt tctttatcgg
    17101 ccgcaaagac tttttccgca tgagtgcctt caaatggtgt gccgtctggt gttaagtagc
    17161 cttgaacaat taagcgatag atttgaccaa tcgcaagacc gtctactttg acccattcaa
    17221 gcacagtttg atttggcaag gccaagatct cttttccgcc atttttattc gtcgctttcg
    17281 tcgtaatggt tggattactg attttgatgg tttggtcatt gtcggtaata tctgcgtgag
    17341 aagccaataa tacgccttct ctaaacagat cttcaaagac cacgacttct ttgcctcgca
    17401 acgcacgtgc gtctagaata aagtctagat tgactgtacc atccgttgtt tctgccacaa
    17461 acgttaaggt acttgtgact tcttttccat ctactagcac tggtttttcc gttactttgt
    17521 ccattagaac accgttgact gtgtatgttt ttccaacgac caaatcgtgg tatttcacag
    17581 cgtctgtaat ggtgactttc gttaatggat taacctcttt caagccagtg ggtttatgtg
    17641 tagccgttgt acgtacactt gggttagtta ctcgtaccgt ttgccctttg tcgttgatgt
    17701 ctttatggtt tgctagttct tcatcatttc taaaaagact ttcaaacacg acgatttcac
    17761 gaccatttat acctgtcaaa tcaaaggtaa atggtacgat caccgtttca ttttctgctt
    17821 tggcaataaa gccaacactc gtttctaccg tatttccatg cacaagcaag ggttcaccgg
    17881 ttgctttatc cattaagatc cctttgacca agtatgcttt tcctggaaga atctcggtaa
    17941 tttcaacggt atcgtttaag gtaaacaatc ctgttgggtc tgcgactgtc aatccgtctt
    18001 caaagacagc cgtggtatga acggttggat tattcacttt cacactttgg gcttcatcgt
    18061 tgatatccgc atgtgctgca acttcaatgc catcacggaa aagtttttca aaaacaacga
    18121 tcgtttgacc tttcagaaca ctagcattaa ccacaaattc aaggtctttt gtgccattga
    18181 ctttgtctgc aataaaggcc aaggtacttg tgatttcttt gccatcttgt aaaattggcg
    18241 cattcgttgc cttgttcatc aatactcctg aaatggtgta ttcttttccg acaaacaagt
    18301 tggtataaga aacactgtct ttaatgacga tcgtttctaa tggatcaacc actttttcac
    18361 catcggcttt atttgacgct tgtgtttcta gttttggtgg aatcaagtaa ttacgtacag
    18421 aaaccactaa cgtttcccca tcatctggcg cattttgttt gaatgcaacc gtgaatgctt
    18481 gtttatctgt atttggttgg aaactttcta atggggcatt ttccaagaag taatagtcat
    18541 cggcaactag acctttcact aaaatttccc cgttttgatc agtggtatat tcaccaattg
    18601 cttgattttt accgttatac aaggtaaagt tcacacctgc gagcggcgtt ttcttcttgt
    18661 tccattcttc atacttgaat aattttacac ttttccgtgc ttgacggttc gcaaaatgga
    18721 tcactttgat cggttctgta tcattggtaa tcgagaacac taatgggttt tgattcaaaa
    18781 cgtaatttac gggggctttg atttcttcca aacgatagcg atcttttcca taagtaagtg
    18841 taccgttagt taggaaaaag cctttttcat tggttttaaa gatatccgtt gtttctgtat
    18901 catttggaat ctccattgtg acataacgat tggctaaagt atcaaaaatc ttgaattctg
    18961 tattagcaag tggaatcact tttcctgttt cttgatccac tttcaccact ttaagacgtt
    19021 gttcaattac tttatcttct aaaacataat ggaaagtttg cccattttca gaaattgtga
    19081 cttcaagtgg ttcaaatagt ttataccctt cttttccttt ggtttcagaa agaatgtacg
    19141 tatcaaagac aacggtattt ttaccaaaag tagcataacc atcattgtct gtcacaacgg
    19201 ttttcaccac tttgccagtt gtttttgacg tcaaagtgat ttcaatgcca gctaattttg
    19261 gtttgttatc tggattcgtt gaatcgacta aatctttatt agcaactttc actaaatcaa
    19321 tggttccttt gatcacttga tcttttgcgg tcgcattgac agtttttcca ggttcaacaa
    19381 caatttcaat tgcttcatca gaaagcacat aaccttttgg cgctttgatt tcttttaaaa
    19441 catatttgcc aggatcaaga tctttaattt ctgcctgtac tttgccgtta atttttttca
    19501 aggtaatttc tttaatcttt ttcccatctg cttgatacaa accatagacc gcattttcta
    19561 aagaagctgc accttgtgct ttcacaccag tttccgcatc ttctttaaac acacgaatgt
    19621 ttccttgttt tagaatttgt aaattaataa cagacgcatt aggttctgtt ggatgtaaca
    19681 caccaattgt ttgagctcct ggacgacgat aggctaatgg cgcaccttga actttaattt
    19741 tattcaattg aatttttgct ttatccggtg cctcttttgt gactgtaatc catacttcat
    19801 tgccgtgaat agatacattg acaccttttg gtttttgaat gtctttcaca tatttcaaaa
    19861 aatcattttt attctttact ttcaacgttt cgccaatttt taccgtatgt gtttgattat
    19921 taaaagttgc tttttcacca aagttattaa tcaaacgttg aatttctgct tttcgacgat
    19981 cataatcaac acggatattt ttgattggga tttttgtgcc caaagcttcc caaatcataa
    20041 attgtgccgc aatgtattgt tcatcggatt tgtctttatt tgtgacatat cctaaataag
    20101 agatcaagct tgtttttttc cgtacatttg aatttttcaa atagtttttc aaagcagtag
    20161 ctgtataaac ttgaccttct gcggctgaga caccaggctc aatacaaaac gccacttgtc
    20221 cattaatctc aaaacgaacc atataattta aagtgaagtt tagattgttc ggactagaag
    20281 taacaccaat attttcgccc caatcaattt tccgaccacc taaaacagct gcattggttg
    20341 cacggcgaac acgaaccgaa cgattggttg gtactgttac taacagtgta ggtgtacctg
    20401 tttttggaat gttctgctct tttttctttt gattttcaat actagccgta gattctttgt
    20461 ttggtttcgt tggttgattt tgactagctg cggttgaaga gattgttttt tcaacgtttt
    20521 cctcattttt tccttctttg tcagcagtag ccgctggttg ttccactgtt tcttctattc
    20581 gtttcttttc ttccgcttgt ttctcagaag actctggctg cacagaaggc gttgcttcgg
    20641 cagctttttc tccttctaga gtggacgttt ctgaagcagg ggttgtaatt gaggcagttt
    20701 cttcaactgg ttgtgaagta ccaggactat tccctgggtg ttgtgtttcc ccaatcgtct
    20761 gatcgagagt cgttttggaa ttgaccgttg gcgcttctgt cacaggggcc tgttcaacag
    20821 tggcttcacc agctgggacc ccggcttctg ctggttggac ttctgtcact tcagaagcga
    20881 cttgggcaat ggcttccatc gtaggttgta tagccgtcgt ttcttctgca tgtgcttgag
    20941 cagttcccac caagaaacag aattgagaaa aagccaccaa tgcgagtgct ttcaaccaat
    21001 tcattttcgt ttttgcatac acaagaattc ctccttttcc tgagaatttt atataataaa
    21061 acaaaacgcc gttaccaaaa gtgataacga cgtgaactgt ctcttctatt tttatctggc
    21121 gctcttatct gaacacattt catcaatgat tttaccctcc cactataatt acagaacaaa
    21181 aaaagaacct gcttcgtgga aatcaactgt ccatttccca attggaatac cagctttttt
    21241 ggcaacttca ccatcaccaa atctcatgcc ataccaatta ctaccttcat ccttaatttc
    21301 tttccaacca tatgacatag cttcatctaa tgaatcaaaa atcatgacac tattgccaat
    21361 tgttacagga tctggcttaa gatcttctgg aagagaaata tcaatcatac cataatgatc
    21421 cgattcctca gtattattgt cattactagc tactggtttg gttgttctac tggcttattt
    21481 tgatacaaca agtactctta ttcttctttt acttctccgt tttcaatttc ccattcaaac
    21541 cactccgcaa agtcttgctt aaaaccatct actcgatacc tattttgtaa ataggcatct
    21601 tctgacgtcg taggatctaa ataggtaggt ttattctctg gacgagcata gacacctacc
    21661 catgtttcgt aatctccttc aaaataacta tctaccaaat agcctttttt tctaagaatc
    21721 tcccgaactt gatttttaat tattgatact tgttcaaaac catcactcat tctatcacct
    21781 caaataactc tagattctca taaatattcc cgacaatttc aatcctatca atgatctcta
    21841 acaaatcgct acttatgctt ccccattcgt ataagaattt cccttccgca aaataaattt
    21901 tccataaact tcttcatgat cgtcccaacc aatatcactc tcgaaaaatt ccacgttgtt
    21961 cttatctttt agctcagtaa atgccataag ttcaacatgt tttccaacct cgaaacaatc
    22021 acaccaccca tcaaccgtta cacgtgtgcc ttcaatacct aagaaacttt gtcctcgtgt
    22081 attaaacact aaaactttcc gcattttttg ctcattaatt aatcacgcgc gaaatctagg
    22141 aatcacaact tattcgcttc ttctttataa atcgccgatt gtaaaattaa gctagacaac
    22201 taaaaaaagt catttgtgct acactcaaaa tagttccgac gaaagaatta taaggagtga
    22261 gtacaaatga cctataacca tcttacacca actgaactcg taatgataga agcttatttc
    22321 aatcaatcac aacctgtttc aaaagtagcc aatctgttac aacgttctcg acaaactatt
    22381 tataaggtct atcgttttct taaatctggt ggaagcgcaa tgagctacta taaacaatat
    22441 aagaaaaaca aacgtaactg cggaagacat ccgattgttt tacctgatga gcaacaggaa
    22501 tacattcaaa aaaaggttgt tcaagggtgg gctcctgatg tccttattgg tcgagcagag
    22561 tttcctattg cttgttcggt acgcacactg tatcgaatgt ttaaagataa aacctttgac
    22621 actcacgatt taccaatgaa gggaaaaaga aaaccaaacg gtcataaaga aaaaagagga
    22681 aaacaagggt ttcgccggtc aatccgagac agaaagacag actataccca gtttgatcat
    22741 gaatttggtc acctggaagg tgacactatc gtgggtggaa aacataaaag cgcggtcatc
    22801 acattagttg aacggctatc taaagtcatc attaccttga aacccgaagg cagacaggct
    22861 aaagacattg aaaataggct gaatcaatgg tttcgttgtg tcccaaaaaa cttatttaaa
    22921 tccatcacat ttgattgtgg aaaagaattc tcaaattgga aaaagattag taataccaac
    22981 gatatttcaa tttattttgc ggatccagga acaccttctc aacgaggatt gaatgaacat
    23041 tcaaatggct tattacgtaa agatggtttg tataaagcta tggattttaa tggtgtatct
    23101 gaaaccttta tccaatcggt ggcatcgaaa cgaaatcata ttcctagaaa atcattacac
    23161 tatcggacac caatggaagt atttttgagt tacgtcacaa aagatgattt gtctaactta
    23221 atttgacaaa cgaaacttaa taaaaaagga agaatattca tgtaaacgat tttattgttt
    23281 ttttctcttt tatacaaaaa gggtcataat ttcaagtaag cggatgaatt catgaggatt
    23341 ttttgcatac tgtctctact atacttaggt cactaagaaa aaggagtgat ttattatgaa
    23401 aaagaacatg attgggacat tattactttc aacacttctt ctaggcggct tggcaacacc
    23461 agcttttgct gagggtcaag cgacttcaaa aggagatatt acctttactg aaccaacaaa
    23521 taccgtggag cctcttaacc ctactgatcc ttcaaaacca gtagagccag cagatccgga
    23581 aaatccagca actggccaga caggtccttt aacactggat gtagttcccg aattgccatt
    23641 tggtacacac gagattgaaa gcggaacaaa aacgtatcaa gtagacgctt caaaaaacga
    23701 tacaccttat ctccaagtat cagatcgtcg aggtgtaggt gcagatggcc aagcacaagg
    23761 gtggaacgtg acagtttcgg tttcagattt tgtaaacggt tcacaagttt tgcaaggcgc
    23821 tgaattagat tttggaacat ccactgttaa aagtacgtca gataacgaat ccactggacc
    23881 aactagtcaa actgtaactg ggttgagtaa agcaagtgca gcgacaccaa tatttacagc
    23941 agcaaaagat caaggtctgg gaacatggct ttctgtttat gatccagcaa atatcacact
    24001 gaaagtgccg aaagcagcag ctggaacatt cacggctgat ttgacttgga acctcgtggc
    24061 tggcccagta gcatagagta tgaaataaat tcaacaaact gcggtgaaaa tactataggt
    24121 gaaggatttt ttaccgcagt tgttgttgaa aggatgtggt ggacaatgaa tcaaagtaaa
    24181 cgactgtttg tttcgttttt ttctatttta agtctatttt tcatttttcc gtcaatcagc
    24241 caagcaaagg attcagcagg agactttgga atcaaaccgg tatttccaga gaaccaaata
    24301 gataaagcaa tcggttattt tgatttatta gtggcaccgg aacaaaatca gacactagaa
    24361 gtaattatca gcaattcttc agatgaagaa cgaacatttg aggtctctgt caatccggcg
    24421 gtaacgagtg atggtggaac gatcgattat agtcaaaaaa acccaacgtt agatgagaca
    24481 ttgccgtttg atgtccgtga cgttttgctc attgcgaaaa aggaaatcaa tgtatcagca
    24541 catgcagaaa caactgtacc tatagaagtg aaaatcccag caaaaagctt taagggacgt
    24601 gtattagcgg gtattcatgt ttcacctaaa gaagaagctg aaacagaaaa tgctacagaa
    24661 ggagcacaaa tcaaaaatcg tattgcttat aatctcgcag tcgttttaca agaaagtcaa
    24721 gagacgatag aaccggatct gaaactttta tcaggagatt tggacgaggt caacgcaaag
    24781 ccaactgttc agcttcgttt ccaaaatcct cagcctagga ttatcagcaa tttgatattt
    24841 acgagcaaga tcttttatga aaatcagctt tatattgaaa atacgtctaa tgcattttta
    24901 gttgcaccaa attcgaattt tcacttgaat cttgatttag ctggtgataa agcaaaagcc
    24961 ggcgattacc gcgcagaaat catagcaaaa tcaggcgaca gtaatgaatg gcgatttaca
    25021 caaaacttta cgatcaaaaa agaaaaagca caaaaagtaa atgaaaattc cgtttttgca
    25081 gtacaagaac aatctttccc atggctttat gcaggattgg ttgctgcagt tctagtgtta
    25141 tggttgattt tgctgttttt gtgggtccac aagaaaaaga aaaaaggaga aacaacatga
    25201 tgaggtgatt tcgttgaaaa catcgatctt attgggaggg attattgcaa gtttgctgtt
    25261 cttcagctgg caagagccag tccaagcaga taccaaaagt tcaggtacga ttacatttta
    25321 tgatctaagt ccaattccgc atccaagtgg ttcagtcaat ggcgcatcaa aacagcagac
    25381 acagctaccg atttataaag aatctaatca acatggcgta ttcccggaga cgaatgaaca
    25441 aaagatccgt tttctttatt tgatcattgg tatagaatta tggcttcttg cgtggttgtt
    25501 gttatggaga agaaaggaaa aggaggatga acatgttgct acaaaataaa ttttcatttt
    25561 ttcgctcctt cttttttact tcgctttttg ttttaagtat atttatcttt tcaccttcgg
    25621 cagaagctgt tggagcaacg cctcctgcca tttcttatga tccatacacg tatgaaaata
    25681 tcgtacctcc aaatggtgga cgtagtgcag tcaatggcgg gaagcttgtc caactaactg
    25741 gggctaacca attgcctaaa ttgactgcta cttatttgaa cgatggttca aatgatcctt
    25801 ggaaaggtgg cacggtccgt tttcattggg aaagccatgt gaaactaaca aatgtacttg
    25861 atttggtgaa tatcactgca caaggatttg catttgtggc gatcatcaat ttgccggaac
    25921 atgtatcaag cagtgatgta ttaaaagcaa ttgactggaa caacgcctac ttgtatattg
    25981 ccggtgcccc catcaaggtt actagcggaa gtttattatc agcaggaagc cataccttgc
    26041 gttttgggat ggggtcgtgg gatacaaata ctctattgac agatattatt gctattatta
    26101 cgcgaggcga attcaacgtg gacgatatcc cgcttcaatt tgatgttaca gctaatgtcg
    26161 cgaagatgac agaaaacgga gataaatatg atacgagtcc aaacaaaatt ttgaccaagg
    26221 gtaaattaca accttctatg tctaaaaagg ccgttttttc tgttgatttt tatgattcga
    26281 ataatattat ccaagatcgt atgttcaatt cgattttagc tccagctgca ggtagatttt
    26341 atcctaaatt aactggcgga aacttgaatc caggagcata tgcattttct gcaagtgcag
    26401 agataaatac gtggaatagt tacatctcac caagtgattc aacaggaaaa tataatacat
    26461 ttgctgatac cacagaatac gtggatggaa ataaccagaa ccttccaggc tctaccaata
    26521 gtcggacatt gacgatgggg ctgactgaag gacgttttga tcagttgcca tttagtcgct
    26581 ttgatcgcgt agtcaactat tttacaggaa aaaacgttac acaaggagca atactgactc
    26641 atactccagc aagcacaagt ggattgaatc agacagccaa tatcgtgtac agtgggaaag
    26701 atgcgcaagg cggattgctt tctcctgttg ctttaaaggt attggagcag tacaagctag
    26761 acggaacggt tttaccaaca aacttaacag ccgatagtca gtggggaaag ctcctttctt
    26821 ctgcatcgta ccaagtcacg gccaattggt cagcaactga actaaaaaag ggttcgatcc
    26881 attacaggct ttattcgaaa ggaacccaaa aattagcgac aggatggaca gatcaacttt
    26941 tccaaacgat ccaatcaaat aacgggggtg taaatacagc tacttctaca ctacctgcat
    27001 tggcttcagg gcaatattat tttgattatc gcttggtgga cgatgtactt actaacatgt
    27061 atccgtcttt tgcgtacaaa tggcagtctg aacaagctgg aatcaccact cttcctcaaa
    27121 taacagtggc taattttcca tctgtgagtg cagatagtca gctaaaaaac cttagcagac
    27181 aacctgagac aggagatccc ctgtctgctc tatcaggaga tacgattcaa gaaaatgtga
    27241 cattcacgtt aacaaaatct ggggatgcga taaccgacaa aaaaatcacg atctcacttc
    27301 ctgaaaatac tacttatatc aatggttcct taaaattaaa tggtacaact atcgcagata
    27361 ccggcattca acaaggagtt tctgtcccag cagatctatt gagcaaaata ggagatacca
    27421 ttcatcttac ttacaactat caattaaata ctgtagatac ttctttacaa tccgtcagca
    27481 tactgacaaa ggcagctgta ctttccagca atattacatt agcagatggt gctaagcttc
    27541 ctaacccagt tgtccaaaca tctgctaaaa caattcttgt ccccaaacaa gaattaacat
    27601 tagttaatgt accagatgat tttacatttg gtaacgatct ccccaaaccg ttgaagacaa
    27661 gttattatga atcaaaaggc gatttttctt ttgatgtgcg ggatactcgg cttccaagca
    27721 cgtctccttg gcaactgaca ggtacattga cttctttatt taagaatgat caaggtcaag
    27781 aattaagcgg aacaaaatta tacttcaatc attctggatc aaagcaattg attcagcaag
    27841 gtcaaaacac gttgatttat gagagtgatg gaacagctaa aggagaggtt ctcgttgact
    27901 ttcccgatac cgatggttta ctcttagagg taaatagcag tacgaatgct caacctggcg
    27961 caacgtatca aggcatggtc acatgggaac tgacagctgg gccaaccagc taagtgatta
    28021 gaatttgtat ggatctgtga taactgtcac agatcctctt tttcaaggat gagaaggaaa
    28081 cttctgctgt taaaatcaga aatgcttgaa ggagtggact tggaactttt cagtttgctt
    28141 gaaaaaaatg aacaacggca aatcaaactt ttccaacttt tattagagga aaaaggagag
    28201 gtttccgtta ataacgtact tacccgctta tcagttgatc gggctacctt gaaagaagat
    28261 ctgttttatt tacaagctaa cttggaaaat atcaaacaat tggaaattgt tatccaagaa
    28321 gggaatattt tattaatcag acatggaaat atagcagcag tcgatgttta ttatcattgt
    28381 tacttgcgct attctacaaa atatcagata cttctttatc tgttggaaaa tggctcattt
    28441 gatcggcaga aacttgtcat ggaacttaat atcagttcgg ctactttgtc tcgcagagtg
    28501 aaggaattaa atgattcttt aaatgagttt catctgaaaa taaaaagcgg gcggctgacc
    28561 ggtccagaaa gtcaaattag ttatttttat ttccaattat tttggtttgg acgtccctat
    28621 cttgaaaaca aaaaagaata cagtgattta tcaggaaaca cttttttaga tctgctgcaa
    28681 aaagagttta gttttgctat tacagaagaa ggacgattga aatttgaaat atggctttcc
    28741 attatgaaga agcgaatgcg ctgtacgaaa aaatccaaac cagattatag caatcttcct
    28801 gttggattgt ttcaaacgac acaattttta ttggacctcc atacattttt gacccgttac
    28861 ttctttcaat atgcctttcc ttggaatcaa aatgaaacgt tggtttttta tcttttcatg
    28921 atcagtaact ttacattaga tacacataac tcgcatgtcc aggagttttt gataagcgaa
    28981 aaatacaaag acgacgtagt agctcaattg aatcgaacgt ttaaacaatc gatagaagaa
    29041 tatttctctt tttatgtttt tccagaagag atttcgcaaa agattgcgtt gacagtgatg
    29101 caaaatcacg ctcattttgc ctattttaga ggatggatga atatttttgg ccaagaagga
    29161 ttaaaacagc ggttaactga agtagaagat aaacaattcc tggttttatg tgaaagattg
    29221 gtcagacaaa catttgctat tgttgatttt actgaagtag acgaggaaaa tgcccgcttt
    29281 gaattatttg ctcgctatgc atctatttta cggacgctga tcaagcagtt agaattacgt
    29341 ctgcaaattg cttatgatct tccttatgaa aggctaatgg cggatatcgt gaaagaaatc
    29401 atccaggaac aattgctgaa tacgatcaaa tatgatttag tcgaatacga gaaagaaaag
    29461 cagtatgata tcattttgac tagccaattg aaagagtacc cgtcacagaa gtccgctaaa
    29521 gtttttgtat tcactagcaa cgaatataat tatgatttcc cctatttgaa ccaattttta
    29581 aaagaatgtt atttagaaaa attgaattta aggatgaata aaacatgaaa atcgtgatca
    29641 ttggtgcttc ccatgaaggc atcacagctg ccctaaatct aagaaaactt caaccgaaag
    29701 cagaagtttt actgatcgat gaagatcata aagatggact aggctatgtt tcaaatggaa
    29761 tcaaccttta tttaaaagga aagatacgta gtttagctga agttgcccat aacatgcgga
    29821 ctcttcaaga aagtggggca aaactgatca ccgaatggag agtaactgaa cttgatccag
    29881 acaaacatca gctcatcctc gcatccaaag aaggaaaaaa cgagaccata acctatgata
    29941 aattaatcgt agcgacaggt tcctctcctg tcaccttgta taaacaaatt gaagctgaaa
    30001 atgtctacac ctataaaaat ctagtgcaat ctaagcaagt acttgccgct ttaaaagaag
    30061 caaaagaagt agtgatcttc ggtgctggtt acattggatt ggaattagca gatgctttga
    30121 gaaataaagg atacattatt catctagttg attatatgcc gaatgtttta tcaagatatt
    30181 tcgataagga tatgatcaac agttttcaaa atcagctgca aactaagcaa ataaattttt
    30241 atccaaatga attcttgatc gattggaaaa aatcagaaga gaaagtagta tccgtacaac
    30301 ttctgtctca aacaataaag gcagatatgg tcattttttc tgcccaaact cgtcctaata
    30361 cgacattgtt aaaagaaaaa gtggctttgt atgaggatga gactgtgata gtcaatgaat
    30421 atctgcagac aagtgatccg gacatctatg cgattggaga tatcgtccca gtcagttttg
    30481 acaaaaataa acggcatctc tttttacctt tagttactcg agctgtacat atggcaagag
    30541 cagtagcgct aactttgagt ggtcagccaa ccgcttacga cctcagacaa aagataacag
    30601 cagcagtcat tatagactac tttttaggaa ctgtagggct gacagaagat gaagcgccat
    30661 tcttggaaca aaataccggt tcgtgttcag gagaatttga tctatttcca caatacgacg
    30721 aagaaaacaa aacagtaaat gcaaagctga tctaccatcc ggatacatta gaaataattg
    30781 gcggacagct gataagccaa gaattcttat tatcagattt gaacctgctt gcggatatcg
    30841 tgaaacacaa aactacgatt ccacagctag cagttgagga ttttggattt ctgtctgaat
    30901 acacctctcg ttttcactac ctcaatgagt tagcttttaa agtactagct aagagagcaa
    30961 atagcaatag agtagataaa agactgtgag aaatatcacg gtcttttatt gtgtggggat
    31021 ataataaata ttaatcaatc gagaataaaa aattcatata atgaaat
//
LOCUS       DAZKCH010000027        30730 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000027 DAZKCH010000000
VERSION     DAZKCH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.027"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(42..383)
                     /locus_tag="ACG84X_001251"
     CDS             complement(42..383)
                     /locus_tag="ACG84X_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFP9127139.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(383..613)
                     /locus_tag="ACG84X_001252"
     CDS             complement(383..613)
                     /locus_tag="ACG84X_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFP9127140.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            900..1238
                     /locus_tag="ACG84X_001253"
     CDS             900..1238
                     /locus_tag="ACG84X_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127141.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(1443..2005)
                     /locus_tag="ACG84X_001254"
                     /pseudo
     CDS             complement(1443..2005)
                     /locus_tag="ACG84X_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(2737..3318)
                     /locus_tag="ACG84X_001255"
     CDS             complement(2737..3318)
                     /locus_tag="ACG84X_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9127142.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(3501..4127)
                     /locus_tag="ACG84X_001256"
     CDS             complement(3501..4127)
                     /locus_tag="ACG84X_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFP9127143.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(4149..5480)
                     /locus_tag="ACG84X_001257"
     CDS             complement(4149..5480)
                     /locus_tag="ACG84X_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFP9127144.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(5635..6036)
                     /locus_tag="ACG84X_001258"
     CDS             complement(5635..6036)
                     /locus_tag="ACG84X_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFP9127145.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(6122..6328)
                     /locus_tag="ACG84X_001259"
     CDS             complement(6122..6328)
                     /locus_tag="ACG84X_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127146.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(6423..7925)
                     /locus_tag="ACG84X_001260"
     CDS             complement(6423..7925)
                     /locus_tag="ACG84X_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFP9127147.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(7943..8398)
                     /gene="argR"
                     /locus_tag="ACG84X_001261"
     CDS             complement(7943..8398)
                     /gene="argR"
                     /locus_tag="ACG84X_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFP9127148.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(8496..9113)
                     /locus_tag="ACG84X_001262"
     CDS             complement(8496..9113)
                     /locus_tag="ACG84X_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFP9127149.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            9334..10707
                     /locus_tag="ACG84X_001263"
     CDS             9334..10707
                     /locus_tag="ACG84X_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9127150.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            10782..11894
                     /locus_tag="ACG84X_001264"
     CDS             10782..11894
                     /locus_tag="ACG84X_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9127151.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(11966..13603)
                     /locus_tag="ACG84X_001265"
     CDS             complement(11966..13603)
                     /locus_tag="ACG84X_001265"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFP9127152.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(13771..14379)
                     /locus_tag="ACG84X_001266"
     CDS             complement(13771..14379)
                     /locus_tag="ACG84X_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFP9127153.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(14763..15914)
                     /gene="queG"
                     /locus_tag="ACG84X_001267"
     CDS             complement(14763..15914)
                     /gene="queG"
                     /locus_tag="ACG84X_001267"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFP9127154.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(15933..16685)
                     /locus_tag="ACG84X_001268"
     CDS             complement(15933..16685)
                     /locus_tag="ACG84X_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127155.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(16826..17776)
                     /locus_tag="ACG84X_001269"
     CDS             complement(16826..17776)
                     /locus_tag="ACG84X_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFP9127156.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(17777..18616)
                     /locus_tag="ACG84X_001270"
     CDS             complement(17777..18616)
                     /locus_tag="ACG84X_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFP9127157.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(18613..19359)
                     /locus_tag="ACG84X_001271"
     CDS             complement(18613..19359)
                     /locus_tag="ACG84X_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFP9127158.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            19597..20967
                     /locus_tag="ACG84X_001272"
     CDS             19597..20967
                     /locus_tag="ACG84X_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9127159.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(21022..21918)
                     /locus_tag="ACG84X_001273"
     CDS             complement(21022..21918)
                     /locus_tag="ACG84X_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFP9127160.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(22032..22202)
                     /locus_tag="ACG84X_001274"
     CDS             complement(22032..22202)
                     /locus_tag="ACG84X_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127161.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(22199..22876)
                     /locus_tag="ACG84X_001275"
     CDS             complement(22199..22876)
                     /locus_tag="ACG84X_001275"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFP9127162.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(22967..23872)
                     /locus_tag="ACG84X_001276"
     CDS             complement(22967..23872)
                     /locus_tag="ACG84X_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFP9127163.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            24047..25501
                     /locus_tag="ACG84X_001277"
     CDS             24047..25501
                     /locus_tag="ACG84X_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFP9127164.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            25517..26548
                     /locus_tag="ACG84X_001278"
     CDS             25517..26548
                     /locus_tag="ACG84X_001278"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFP9127165.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            26555..27742
                     /locus_tag="ACG84X_001279"
     CDS             26555..27742
                     /locus_tag="ACG84X_001279"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFP9127166.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            27898..29280
                     /locus_tag="ACG84X_001280"
     CDS             27898..29280
                     /locus_tag="ACG84X_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFP9127167.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            29317..29637
                     /locus_tag="ACG84X_001281"
     CDS             29317..29637
                     /locus_tag="ACG84X_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127168.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(29837..30505)
                     /locus_tag="ACG84X_001282"
     CDS             complement(29837..30505)
                     /locus_tag="ACG84X_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFP9127169.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT         8641 a         6272 c         5575 g        10242 t
ORIGIN      
        1 tgtttagcat ataaaaatat tatagagttt acttacaatg cttaaaacat atactgtata
       61 atctgatcaa ttttagccat gtcttgcaat ggtaagtttt ctattttttt gagttttcgt
      121 tccttaaaat caagagattt taattgtgta ataattactt gtccttttat atctagctct
      181 tcaggtaatg agtaacgtgt cggtaaattc tttatagtgg aagtaattgg acatatgacc
      241 gaaaacattg ttttacggtt aaattcataa cgagagacga ctagtcctgg tcgtcttttt
      301 tgaatttctt ttcctacgga gggatcaaaa tcaatccata caatatcacc ttttttagga
      361 atataaattc tttcttctga cactataaaa tttctctccc ttcaggagtt aaatcttccc
      421 attcgtcttt ctcataatac tcggcctctt ccccaccact aaatggatct tcaatttttg
      481 gaactaacgt aattgttcca tcatcagaat acacaacgat atattcttgg ttttctgaag
      541 gtttctttcc gttatcagaa ggtaaagtta ccactacaga acttccttgt aatctagatt
      601 ttgtaacaag cattatcatc actcccttaa taaaagtata ctatataaca ctaagtaacg
      661 caaaattccc ctttgtaaac tatctagaaa attgttttgt ttaaagtata tcttattgga
      721 tataaataga aataaattgt agccagttca ttttttcttt aactaaaaaa ataatccaag
      781 aaacattgaa cctatggatc caaaagctac ccaaatacta tagctaaccc cccgctacct
      841 tcaattttgc agataaaacg ctttgggaga aaatttcaaa gacaacaggc catcctatca
      901 tgcccgatta taaacaaaaa gctggctatt ccttttgctc tgacaaattt caattgggaa
      961 agttcacgaa actagcaggt gaagaagttt caactgttcg gatcaaagaa tgcccgcttc
     1021 aaatagaaac attggttcaa cgaatttcaa ctagacaaga ctttgctatt gtagaacgtg
     1081 agatcgtagc tatttttgta gaagaaggga ttttacatga tccaactcat atcaatgtgg
     1141 ataaatggca acctcttatc tataaattca gagaatatac aactgccaac cagtcgttaa
     1201 ctttgaattt tagattccaa gaattcaaag agtcataatg ataaacatcg ttaggtataa
     1261 ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag ctatacatta gaaaggtcga
     1321 ctgtgaccct atagatgcag tatatgcagc ttatgagcat ttcttctgtt ctctttgttt
     1381 ttgggatctg tgctgaagtc tttttcgttt tttgccgctc tttctttgaa aaatcgatta
     1441 tgttatacct tctccattac taattcaggc atctgctgag taatgatttt tcgcgcaaaa
     1501 gaaatatctg ttacccaagg ttcgatttgt tcttcagtca agacaagcgg cattcggtca
     1561 tggattggtg cgactgtgcg gttaggttca gtagtcatta tgattgattc tgccattttt
     1621 tcatcctgat ggctacgata aaaaccgcca atatacacta ttttttcctt atttgaaaac
     1681 ataaatttgt ctttttcttc attccactca ttgggaaaac acaacgattt tgcaaaaatg
     1741 gttgatgaaa ggtctttttt tcttctactg tctctgcacg ggcattaatc atcaattgtc
     1801 cttttttaaa tccggtaaat ccccacttca tgatttccgg agtgaggatg ttttcttcct
     1861 cttttcttaa cgtcacaaca agatttgacg gaaaaacttc tccagctgct aattctgctg
     1921 cctgcttcgg ttgtttcgtc tgggcttctc gataataatt ctgaaggagc tctgactcta
     1981 gatcaaaaaa ataacgacca cacatcctaa tccctcccaa tctttttttc tatcatacac
     2041 tgcaacaaga agttcgcacc aacaaaacgc tttcaatttt tgtagaacta aaaaagttgt
     2101 gacaagtgac aaactctcca gtgaatggta ttctcctgcc aactcctcgg tcacaagtca
     2161 caatattcaa caaacatgag aagctgcttt ttgaaattgt tccttgtgac tcggagtgaa
     2221 acggcaggct tacgacctct gggtaaacgg tgttcaaaag ccagtttctc ggtattaagc
     2281 caaatttatg caaaaatgta gaaagctatt ttcacaaaat ttttcttaat actcgaaact
     2341 aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat
     2401 aagcccaacc aaacgaaaaa tatgagcagc tatttttatt tggctgttct tattacttga
     2461 tgcagggcag ctttttcaca acctctccac taaacggtgt tcaatcagct aaccttcggt
     2521 attagctcaa aaaacggcaa aatatgagga actattttgc cgtttgtttc tctaatactc
     2581 aggtcaaagc gctgatttca caacctctaa tacacggtgt tccagaagta gcttcttcga
     2641 aaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt
     2701 cttgaagctg accacttctg tcacaacctc taattattaa agaacctttt gcgaagttaa
     2761 caatctttct ttgatcaatt gaaaattctg cctaagtagt gatagatcct gtgtgacttt
     2821 caacaataag atacttccct ggatttcagc aatcaacgct ttggcttgac ggtctgcttc
     2881 ttcatcggac agtttttctt cagaaagtgc caggatattt tgtttcgtat acttgaccca
     2941 ttgattgact aattctagta gcaacagacg gtattcttca tccactgtac tcaactcaat
     3001 aatcaaatta cctacaggac agccatgata agtgatctgt gtctcatgat cagcgaaaat
     3061 ccagtccaac atttcttcta atgcttcttc tggctgtttt ccagcattta agatgtcttc
     3121 gaacaattct gtctgccata cgtccatatg cgcatggatc accgctagac aaacttcttt
     3181 ttttgaagaa aagtaataat aaaattgacc ttttcctgta tcagaagctg ctagaatatc
     3241 tcggattgac gtttcatgat agcctttttt ataaataaga tctttggtcg cttccaagat
     3301 cttttccttt gttttcaatg atattctcct ttttcatttc tcatagtcct atattataca
     3361 gtaaattcat cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca
     3421 cagccctcac tataaaactg ttctcatata gctagatgtt cattgattca agaactgcga
     3481 ggacaaaagc aattcctatc ttatgatagt tgctctaata cttcctctgt tgtcatcact
     3541 tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg gccaggagca
     3601 ccaattgcat ctgtcgctac cacaacattg aatccactct ctaccaattc acgcatatgg
     3661 gaatcgctac acaagtttcc gttcattcca ccaagaatta ctgtgtcgat tccatttttt
     3721 ctcaattgga gcgccaaatc attgctttct ggtccaaaga ttttatgagg agagctgatg
     3781 atcgtatttt catccaaata aggtttcaat tcttcgataa aatcggctcc tgaaccttct
     3841 tccactgatt catattgact ttttctagca aacatctgct gctcaagcat catatgttct
     3901 cctgcaccgc caaattgcca tttatggtca tgtgggtaaa aataatgagg agaaataaag
     3961 agtttgtatc ctttttcttt tgcttgtttt accatttcaa tcatattttc gatcgtattg
     4021 tatttttcta agatatcttt tgtcaaacca aagccaccgc ctgctggttt caagaactcg
     4081 acttgcgggt cagtgagaac tactgctgta tttttattat tgaacatggt ggattctcca
     4141 ttcgttattt attttaatac atcatttaga gcttcactca ttgtcggatg agaatagatt
     4201 tgatctctca ataacgtata aggaagtttt ccattcatag ctagcgaaat caagttgatg
     4261 acttcatgag aatcttccgc atagatactt gcccctagaa tcaagtcagt ttcagggtcg
     4321 actaaaactt tgaatacacc tttaggatct tctaatactt gtgctttagg gacaccgctt
     4381 gtcatatact tgaataattt gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa
     4441 cctacattgg ataaagtcgg agtgataaat acactgtaag gcacagcttt ccggttattc
     4501 gttgttcgtt tattctcgcc cttcaactga tccataatga ttcgataatc atctagagag
     4561 atataagtga actgcaatcc gcctttgacg tctccaatcg cccaaatgtt gtctgcatct
     4621 gtacgaaggt attcatccac agcgattgct ccgcgatctg ttagtttaac atctgtattt
     4681 tctaatccaa gtgatgctgt acttggtttt cttccagttg cagccaaaac ttttgacgct
     4741 tggattgtta cttcttggcc atcttctgta aaggtgacgg cagctgttga ttcttggtct
     4801 gctacttgat ctacagatac acctagatgg aattcgattc ccgcatttgt catgtcttct
     4861 aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa attcagaatg ggcatcaaga
     4921 acgacaactt tagatccgta ttcattgaac attgatgcaa attccaagcc aatatatcca
     4981 gccccgatga tcactaattt ttccggtaat tgttcctgat ccatcgcttg cgtagaatca
     5041 atcaagtagc gacttgtatt caatcctttg attggtaaaa tgattggttc agaaccagta
     5101 ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac cattattcgt cacttcgatt
     5161 tgatggttag aaagaaaacg tgctgtaccg tccatcactg tcccagttgc ctcatcgctg
     5221 atcatatgat aatttttggc gcgaagcatg cccgtcaatt tttctttccg agcaacagcc
     5281 tctgtaaagt cgattcctct ttctccattg aaaatcaatg atttagaagg aatacagccg
     5341 atgttgatac atgttccgcc atacatacgt gttgactttt caacgactaa aaccgattca
     5401 ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc gatcacaata
     5461 ttttgatatt tttccatcat ttttccctcg cttctttttt acctaccgat tggtacaaaa
     5521 atatgataac cgataattgt ctattctcca aatcatctgc tttatttgtc aaaaaaaacc
     5581 agacaaaaag cggtcctttc acgtttttag tctggttcga tttcctttat tcttctaaac
     5641 aatcgttact tctacatcga tatttcctct agttgctttg gagtaagggc agaattcatg
     5701 cgcatcttct gcaatttttt gggcttcttc ttcgctgatg ccatcgatat gcacttctaa
     5761 tactacaccg atctgatagc cgccatcatc taaattataa agagagacac gtgcttttac
     5821 tgtggactct gctgtcattc ctgcttcttt gatcatatgt tgtaccgccc cattgaaaca
     5881 agaagcataa cctgctgcaa ataattgttc tggatttgtt ccttctgcat ggattcctgg
     5941 aggagtgatt ttcatatgca tcgagccatt tggtgcctcg acttctccat tgcgcccgcc
     6001 atggttgatc attgctgttt cgtatgcttt tttcattgta ctgctccttt cgattgacca
     6061 tttgctactt ggctataatt atagtgtatg acaagtaagg cgctttctac aaaaattctg
     6121 cttattcgaa taccagaatg ccgtcttcta ctatttttcc aaaaaacaaa aaaatactac
     6181 tcgtgaacaa cagcgtcata tttgttccaa aataaatagc aatcttttct acataatctt
     6241 ttatatgatt gattttaaga tacatatata ccagaaagtt gaccccataa accaatactg
     6301 ttaaaaaaat aaccatattc gttaccattt tttcctcctt ttgctggtct ccctaccagc
     6361 actcgattta accataccac tttttttgcc gtccaagcaa ctagcctttc aaaaagactg
     6421 gtttattctg ctgttaatga ttcaagatca gaaaaatgtc cgaataattt tgctaatttt
     6481 actaacgcca acttgttctt tccgaattca tcattttcta tctgtaatac tagtaacggc
     6541 tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt atggctcttc tagatcatat
     6601 cgaatacctt cttcattttc cgggtcgaag ttcatccctt tttcttcttc caacagtcgc
     6661 ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt catcgctgaa caattttaat
     6721 cggatttctt gtacttctac gggctgtttc aactctttga tttgttcatc taatgtgata
     6781 ccttttcttt ttaattctgg caaaagcatc aggatctttg cgatgacata tgcaccatca
     6841 tccagaaaat agttttcctt gaatgcagcg tgtccgcttg tttcgatggc tagctgtgta
     6901 tctttcccaa gacggttaag ttctaatgct ttattgatta catttcgata gccggaaata
     6961 taacgaactt ggatgcctcc tttttcttca atgaatcttt gtagatgaga agaagtaggg
     7021 gaattcgtca cgattcttgt tcctggatgc tcttttaata cgattgtact taatactgcg
     7081 atcaaattat ttcgattgat cactgttcca gaagcactga caactgcaga acgatccaca
     7141 tctgtatcga aaatgatccc aagatctgct tcatttgcta aaacagcctg cttgatactt
     7201 tccatcgctt ctttattatc aggatttggg atatgattag gaaatcggcc atctggttcc
     7261 aaaaattggg aacctgttga atccgcacct aagctattca atactttttc agcaaagaat
     7321 ccaccagcac catttccggc atcaacaatg attttccaac catttagtgg tttgctttct
     7381 agtgttccaa tccccttttt aatttttgtg actaaatctt gcgcataagg tgtcaaaagg
     7441 tctgcttttt ctacgcttcc agtttgttcg ctttttattt tttgctgctg tgataggata
     7501 aaagcaatat cttctttttc tgctcctcct tctgaggtaa agaattttat tccattataa
     7561 taatagggaa gatggctagc agtcagcata accgcagcat cgcacgagaa ctgttcaaat
     7621 tgagtggaca taaacatagc aggcgtagta gctaattcga aatcgatgac atgtatccct
     7681 tgttctttca gactttggat caacgcctct ttcagtgctg gtccgcttat cctactgtca
     7741 tgaccaatcc caatcgtcca ttttttattt ggatcggttg atttcttctt tttctttatc
     7801 cagtttgcta gtccccagcc gatctttttt accatgtctg tcgtcaagtt tacttcatat
     7861 ccttcaactg gtaatgcgat tcctcgaata tccgatccat tttgcagcgc tttcatatct
     7921 ttcatataaa agtcctcctc atttattccc tcattttttc cagcttttct gcaaatcgct
     7981 gtgcttcttc ttctgagcgg caaataataa tgaatgtatc tacaccggcc atcgttccga
     8041 caacttcagg gtaagccact tcatctagcc aattcgttac cacatcggca ccatttcgtt
     8101 cagtcaatac gataaccatg aactgaacag actggatacg caaaacctcg cgtctaattg
     8161 ctgtacgcaa acgttcttca tttaaagaaa cagatggctg gttaaataat gtatagcgta
     8221 ctattttgtt ttcattttga ctttttacta acttcatttc tcgaatgtct cgagaaatcg
     8281 ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc aagcagctct tcctgtgtcc
     8341 caataggttg ttctgtaatg atctggcgga tcagtgcttg tcgctgtttc tttttcatat
     8401 tagacacctc tcaatgttga ttatagcaaa agataagtaa tatttcttca tattttggta
     8461 ttttttactt ttattttttg ttttcattca ggttgctaac ctttttctat tttaacacgc
     8521 aaaatcgtct tcattttttc aggtgctgat tttcttggat cgctgatgta aatctctttg
     8581 tgttctttag aagctctttc atagccttct tttgcgatga atgcttctaa tttctcaaac
     8641 gttgctggtt cttcggcata gggcccgacg tgtaagattt gggcacaaag accttcttcc
     8701 atctttttga atactacttg ttctttcaag tcttccggaa gtttgctaga acgctgaatg
     8761 gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc ggatcatcaa ttgataagaa
     8821 aaatgttctt ttttcatcac tggttcatgc aaatactttt cttgcagtcc ccattgtcct
     8881 tccagtggat agacagtata catctgataa tcaggaatca gccaattttt tttaggcgac
     8941 atgcgtattg catagctgac tgcatataga caggctactc ttcgtttaaa gtcttcctga
     9001 ttcgggtcgc cgatccctct gatgctaaag aatgattttt taggaacctc tagtatttgc
     9061 gggctttttt tcatactata gctcttgtct ttacgccatt caattttttc catttttctt
     9121 cctccgcgaa attccattta gttatttatt atcatacctc tttttgagtg acttggctaa
     9181 tcgtgttgac actatttttc agtttgtgct agaataagtg aagtaaataa atcgtacaga
     9241 taacacgttt cggcgtgtcg agagagaggc ggtttctatt tttataatag aaatcactct
     9301 ctttttttac gaaatttttt agaggtgatg taaatgacaa aacaaaaaca gctgctttta
     9361 gtacctgcag taattgcaac agggatgatg tcttttgcgg gcgtattgat cgagacggcc
     9421 atgaatgtaa ctttcccaac tcttatcaga cagtttgatt taacgactgc acaagtccaa
     9481 tgggtaacaa cgatttatct tttgatgatt tcgatcattg ttccgctgtc tacttatttg
     9541 aatcgcaatt ttagtctcaa aaaactcttt ttagcttcaa atctgctttt cttggcaggt
     9601 ataatgatcg atttcttctc tcctaccttc atggtcctat tgtttggtcg attgctccaa
     9661 ggtgcagcga caggtatcgc tcttccgttg atgttccata ttatcttgac atttgccccc
     9721 ctcaatcgac gaggcgcgat gatgggtgtc ggtactttga caacggccat tgctccagca
     9781 attggcccca cttatggagg cattatgact tcacatttta catggaatca tatcttcctg
     9841 tttcttgtgc ccgttttgtt tctttctttg attatcggct ggtttgctat tcccgagatg
     9901 gcagtacaaa aaagtggtta tttggattgg ataagcgttt taggaatttg tcttttgttt
     9961 agtggaagtc taacattttt gagtacgttg ggaacagttt ccagctggat tgctttaatc
    10021 atcggcggta ttggctggtt ccttttttac tatcgaagta aaaaagtgga gcatccactg
    10081 atccgactgt ctattctttc aaataaaaca ttccgcttgt ttttgattgg cttcttagtt
    10141 tatcagtttt tattacttgg tgtatctttt gtcttgccga atttccttca gatcgttcaa
    10201 ggaagtagtc cttttgtcgc tggattagcg atgcttcccg gcgcagcggt tggtgctttg
    10261 ctttctcctt tttccgggaa aatgctggat caatatggtc cgaagaagcc aatttttgct
    10321 gggctgattc tttctttgat tggttggcta gcattattcc tactcatagg acacgcttca
    10381 gtgggtgtat tgattgcttg tcatgtgttt tatatgatcg gtatcggatt atcttacagc
    10441 aatatgatga ccaccggaat gaatgcactg aatgaagaac tacaaggaga cgggaacgca
    10501 atgttcaata ccttgcagca gttttctggc gctgtggcta cttcattagt agcggtcatt
    10561 atcaattacg tccagcatca tacttcccat aactatgaag tgtctactac attaggatca
    10621 aaagcagcat taggcgtctt gttgctgttg cttctcgtaa gctttgctcg attcgcctat
    10681 tatctgttct ttgctaaaaa agcgtagatt ccatatacgg caggtgttgc atctgccgtt
    10741 tttttgtgtg aaaatggttg tttgtaaaag gaggcttttt tatggaaaaa attgccatta
    10801 tcggtggcgg gatcattggt atgaccctag ccagttactt agatacatca aaattcaatg
    10861 ttgctttatt tgatgaaggg acaggacagg caactaaagc tagcgctggg attatctccc
    10921 cttggttgtc gaaacgcaga aacaaacaat ggtatcgtct ggctaaagac ggcgctgctt
    10981 ttttccctaa acttataaaa gatttccaac ttgatcaaac gatttacgca caatcaggga
    11041 cacttttgct tcgacctgaa aaagatttag ctgaattggc tgttcttgcc gagaaacgaa
    11101 aagaagaagc gccagaaatt ggaaacatcg aatggctttc acctgaacag acatctcaag
    11161 cacttccgtt attgaaacca gcagtttcac tgcgtatcag tggtggtggt cgtctggatg
    11221 gaaaagcata tttagaacat cttggtcagc gtttagcaca aaaacaaatg gagcagatcc
    11281 aggcaaaagt cactttgcat aagaagagcg attcttggct catcaaggga ccgtttggag
    11341 aatacacagc tgatcgtgta attttgacac ctggcccggc acttaagcct ttattacaag
    11401 aattaggcta tgctgcagat atacgtccgc aaaaagggca gctcttagca tttcagacat
    11461 cttataagat gagtcaagac tggcctgttg ctatgcttga cggagaagct gatttcattc
    11521 ctttcatgga tggaaagatc cttttaggtg ctacccatga aaacgatcaa ggctgggatt
    11581 tggctcctac tagcgaagct tataagggat tgactaagag tacagaacag ttcttgactg
    11641 atccagatca gataaaaaac tggccatacg agttccgtgt aggtacccgt gcttatacgt
    11701 cagatttttc cccatttttc ggcgtactgc cagatgatcc aagcttactg gctgctagcg
    11761 gtctaggctc ttctggcttg accacaggtc cttatatcgg ctatctatta gccaacttct
    11821 taaatactgg tcattggcct acggaagatt atcaaaagga catctccacc tatattacga
    11881 aaaatccatc atagaaaaac agctttttca agtaaggatc ccgagcgata ttgcgcatgg
    11941 attacttctt gaaaaagctg ttattttagt tcaatttctg aatcaaattc tccaaacttt
    12001 cttttgcttc atctggcaag agatcttttc ctatctgagc ttcaatgaat cgtaaacgaa
    12061 tatcaagtcg ttgtttcacc agatttttat aggacgtatc ctcaaaagaa acaggaaaat
    12121 ctggtatagg taaatagtgg atgtcttcaa atggaccaaa cgacttgaat tctgccgttt
    12181 gttgcacgat tctttcaacg attgacaatg tcgtttcagg tttgattttt ttatcatcga
    12241 aatatccagt attcaggaca tagcaggctg tttgctgttt caaaaacaac tctcgaaaag
    12301 cttgatagtc ttccctaaga ggatagacac ggaaaggatt agcaaatggt tcaatgacta
    12361 gctcatctag ctgtcttttt gtagtgatat tttccgcgtc tgatcgtttt gttgctaatg
    12421 ttgcaccaaa agacgctgct aaaactgggt cattgatctt gataattggc ggaagcgaat
    12481 catctttcat gatccaaaaa acagcatcga tcttttcgct aagatgatcg actcggtcgg
    12541 gtgtcgcata acgtgatttg actgtccgcc catttccgtt tcgtatatct cctgttacta
    12601 ggactttttc tcctttactt gtacatgtca cgcccacatt ctgacaagta aggaaagaag
    12661 aaatggccgg atcatcagac ggatagtctt gtgttttatc aaagtaagaa ggttccaagg
    12721 cagtagcaaa accatttttt cgagaaataa cgaaagcatc gtcatgcaag atcgaaacag
    12781 agtgaccttc cgtatgtttt gctaaggtaa tcgttgattt tccagaaccg gacaacccaa
    12841 atacagccat cgtataggtc tggtcattac tagcatattg tttcatccca ccgtggcagg
    12901 caataaagcc attgcgattt cccaatgccc aagcaagcgt caaagtcgct ttttttaatt
    12961 ctccaaagta acgtaatcct agcacagccg ctgtattatg gagagcatca aacaaaatga
    13021 gtccatttgg aaatgtttca tgtgtccatt cgggatcaca aaagatataa agatctccct
    13081 catcaaagga aacagacttt tgataagtct ctaagatctt cgaattcgct ggctgaaaat
    13141 tcagcaaata agaatacaaa ttgttctcaa atccttctgg aatcagcaaa tgactttgca
    13201 cagaaaattc ttcagatagg ccaacgatta cttttgtatg gtaaaactgg cgcttgcgac
    13261 tttgatacac agcttctctt aaaattttct cgtatttgct ttgttccttg tctaagtcct
    13321 caaagatccg ccgagcactt gctgttcttc ccacaatgct tccatcattg aatactagtg
    13381 tcctaacatc agctggtaaa tctagttctt cagcatgtga gattgttaaa tctgtgatga
    13441 tcgttcctgg actccctttt gctagttgat aagctgtctt cctatcaaaa acttcatgaa
    13501 cattattacc gtaaaatgtc gtttctacaa tcgatcgaat actggataac agtggatttc
    13561 cacttgtgat ttcgtttaat tcgagactct cttttgtact catggctcct cctcattccc
    13621 taaacaaaaa aacgttttct ttattataca ttattcgagt ttttatttgt actgctgcgc
    13681 tgtgggaagc aaacgagtta tttttcacac aaaaaaaccg agaacttgaa taaacaagtt
    13741 tctcggtttc atcattttcc ttttatcggc ttagtaccag ccgtttgcta accagaatgt
    13801 tttagcagca tcccatgaac cataacgaga tgttacatat tgttctgcta cacgttcttg
    13861 attggcagct gaatagtcgc cgtttaagta tgaagcatct aattgataac ggccgatgta
    13921 acgtccgtta gtagctgtgt atgaaccgcc tgattctttt tgtgcgatcc attcttttgc
    13981 agagcttgaa gttggcgctg ttgcagcagc tggggcagca ggagctactt caactgtttc
    14041 aacaggtgca acgtatgtat gttcttgcgt tgctgtttca gttgtagatg ctgtattttc
    14101 tgttgttttg ttttctgttg ttgctgaaga atcatttgaa gttgggattg ttaattgttc
    14161 accaacataa atgcggttga tgtttgcgat cgaatttttt tcagcaattg catcgatcat
    14221 tgagttgtct cctgcaaatt tttgtgagat cttagataat gaatcacctg attttactgt
    14281 ataaacttca tcagcgtgag catttgtagt tcctacaaac attgcagtag caccagcagc
    14341 aaaagttgta cctaaaacaa ttttcttaaa tgaattcata ttaaactcct ttttttctcc
    14401 gttttttatt ctttcgacgc tattaacttt atcatttaga aatatttcat aggtaaaaga
    14461 aacatgacat ttaatgacaa aataacgaat tatttaatat ttgtaacatt taaacaaata
    14521 tttttttgat acaaaaccat aaaagccttg ttgtataagc aaagtaatcg tttttctatg
    14581 tttttttatt tttgaatgaa aaacgcagat tctgtaacat tcactgcaat aatccataaa
    14641 aaaaagcaaa aaaatttttg atttttatca aattctctta aaaaaatgta aaaaatacaa
    14701 aaaaaccagt aattgttaca acaattactg gacaaaaact ttgaataatg ttaactattt
    14761 ttttatttta actttctccg caataatttc tgggcatgtt ccaattcgtt tataacgact
    14821 tcttctgttt ctttagctaa tatttcatct aatacatcaa gccatttttc cggttctttt
    14881 gttcctagac gtccaatagc ccaagctgct gttcctctga tgacagggcg gacatctgtt
    14941 aaacattctg aaatctcagg caatgccgtt cgatcaccta gattagctaa agcaatcaat
    15001 gcgtttctct gcaaaggttt cttcccacgc catgaaccag ctaaatgccc aaattgctgt
    15061 ttgaagtctt tattagacat cgaaagcatt ggctttaatt ttggatatat ttcgtctact
    15121 tttggttcca tctcttcatg aaaatgaaaa tcttttcctt gattgtaagg gcagactaac
    15181 tggcagatat cacatccata aatgacattt cgcatttttt tacgatattc ttccggcatc
    15241 atcccttttg tctgagtttg ataagacaaa catcgctggg cattcattct tccgtcacca
    15301 agcaatgctt ttgtcggaca agcagtcacg cagcgcatac agtcaccgca accaaattct
    15361 cctggtttat caggctcaaa tacaatatta gtaacgatct caccaagata gacaaatgaa
    15421 ccgaactctt cagtgatcaa caatccgttt cgtccaataa atcctaaacc agctcgctgt
    15481 gctacagcga catcgatcag ttctccagta tctacttgcg gagctagacg ccattcctct
    15541 tctttttgcc atttttctgc tcttgtttgg atgaattcga tcaatcggtt caaacggtct
    15601 ctgagtatat catggtaatc gatcccccaa gaagcacgag caaactgccc gcgtttttca
    15661 tccctaggca cttcttcatg gatcctagta ggatacgcaa gtgcaatgga aatgatcgat
    15721 ttcggctgat caaatgtcat ttctggataa agacgctcat cgatatttgg atgttcaaag
    15781 ccagaagtat ggccagctgc tttttgttct tccaacgatt cttttaatga atcaaaaggt
    15841 tccgccgtgg tgaacccgat tttgtcaatt cctaatcgtt tgctttcttg tatgatttct
    15901 tcttttaatg tcatggtctt cctcgcttgc tgttaacggc tgtataaccc ataatatagt
    15961 ttttcttttt tcagctggac aaactggatc tgctgatcgg caatcttctt ttcttccatc
    16021 catttttttc ttgcagcaaa tacttcccaa taatttgttg aaattaattt tcttttgtta
    16081 tctaatgcat taaaaaaatt caatgaaact ggttttgtac ttaacagttc atggagcctt
    16141 acctcttccc atggcgaaaa ctcagacaga tcgcgggaat acaatacttc ttcatagaga
    16201 tttttttgct gtgtgtacgt gaatgtttgc gggattttcc caggcctagc aatttctact
    16261 agacgattat aaaacatatt cattaatttg ctgttggcaa taaattgact tttataatag
    16321 gccgactgga tctttttgat tactccttct gctttgatga ctgaaaataa tgcaggccat
    16381 gctttgacgg ttatttcgtc gttttgttta actaatacgc caggtgtgaa gccgactgga
    16441 gaaaggaaca caaaataacc gataccggta ttttcatcta aaggctgaaa ttcatcaaac
    16501 aaccatttgc ctatgtacag ctcttcatct ggttctgttg tctcattttg atttgctatg
    16561 aataatttag ctaattctgc ttcaagaaat tgaaggtctt gatccttgtc ggtattttcc
    16621 tgctggctga tcaatcgaaa gacttcttct ttaatcgtat atttatcttt acgtgtaaaa
    16681 ttcatagcca caccttcctt ccttactcta actataacgg aatttcttca aaaaaggtat
    16741 ctgtacgacg aaaaacagca taattttttt tcatatctct tataaaaaat gcaaggtctg
    16801 ctcctcaagc tagaccttgc acttttcagc tttcttttgt ttgtgacaaa ccttcatgga
    16861 tcgtttcaat attccatttc atcatctgat agtaagaatc tccttgttct ccttcttttg
    16921 ctatggaatc agtgaacagt ttatcataga ttttcaaacc cgtttctttt gctacccgtt
    16981 ccatgcttct tgagtctaca ctggtttcca cgaataaaac cggtacttct tttgctctta
    17041 tctgatcaat gatcgctttc atttgatcag gcgtaccttg actttctgta ttgatctccc
    17101 atatataagc tgctggcaaa tcatatgctc gtgaaaaata cttgaatgcc ccttcacttg
    17161 ttactaataa ttttttgttc tcttcgatag aagcaaaact ttccttcgct tgtgtatcta
    17221 attcttttag tttttccaca tatgcttctg catttttttt atagagtgtc gcattttctg
    17281 catctttttc agagaatata cgtgcgattt cctccacata ttttattccg ttagataggt
    17341 ctagccaagc atggggatct gcttttgtat gttcttcacc gctagttaaa taaagaggtt
    17401 ctacattttt gctaactgca aaataatctt ttccttcttc ttttttagcc gtttccatca
    17461 agttatcgaa ccagctgtta cctgtttcaa gattcaaacc gttgtataaa ataacatctg
    17521 catcgcttgc ctttttgatg tcttctggta gtacttcata ttcatgcgga tctgttccga
    17581 ctggtacgat actgtggata tctatttgat ctgttccgac ctcttttgcc atgtccgcca
    17641 agatcgaatt ggtagccacg actgacaact tttctttact tccttcatcc gcttggtcag
    17701 aagcctgctt tccgcaaccg gctaatacca agaaactaac tgccaagatt aaaaagagtg
    17761 atttttttgt tttcatctat ctgcttcctt tctgaaataa aattcctttt gttggagaaa
    17821 ataaaaaagc aaggataaaa aatgcggtac atgctaacac gatcgtagct cctgatggcc
    17881 aattgtaact ataactgaaa aacacaccga caactgcact tagcataccg attcctgcag
    17941 ctgtaatgat cattttcagt aaatggttcg ttagcaagta agccgtggcg gctggtgtga
    18001 tcaacatggc aatcaccaag attgttccta ctgtctgtaa actgactaca gccactaatg
    18061 tcaaaaagaa catcaaaaga taatggatca gcgatgtgtt cagcccataa gcttttgcca
    18121 ttgtcggatc gaatgatgtg atcttcaatt ctttataaaa gaaaaagaca aatatcaaga
    18181 cgattccact aacgagtgct gtcagcaaca aatcgctttc cctaacagct aagacattcc
    18241 caaataaaat atgatacaaa tctgtcgcac tctgggcata tgaaatcaag ataatcccta
    18301 atgcaaaaaa ggagctaaag acaattccaa tcgctgtatc atttttcaat cggctccgct
    18361 gagtcacgaa accaatcact gctgctgtta gcatcccaaa agcagtggct ccaaagatgt
    18421 aactaaaacc aaacatataa gaaatggcta cacctggaag aactgcgtga gagatagcgt
    18481 ctcccatcaa agacatccct cgtaaaataa taaaagaacc gatgactcca gaagcaagtc
    18541 ctacaagcat ggaagtgacc aaagcgtatt gcaggaattg ataattcatt aatccatcaa
    18601 taaaggattg gatcattttt tctctcctcc ttttactaaa tgtctgatga tctcaccata
    18661 ggccaattga aggttcttcg atgtaaagac ttcttgtact ggaccggaag cgatcagctg
    18721 tttatttaaa agaataacct catcgaaata ttcttctact ttatgaagat catgatggac
    18781 gatcaaaatc gtttttcctg aattcttcaa ttcctgcaag atgtcaaaga tctttcgttc
    18841 acttaacgca tcaatcccta cgaatggttc atctaaaaag atccattctg ctccttgggc
    18901 tagagctctt gcaataaaaa ctctctgaag ctgtccaccc gatagttcgc tgatctgtct
    18961 tttggcatat tcttccatcc ctactttttt caaagcttgt cttgcacgtt ctttttcttt
    19021 tttcccaggt ctttgtccaa ttcgtaaaga tggatatgtt cctaaaagta caacgcctaa
    19081 tacatcaatt ggaaaggaaa gatccaattc acttcgctgt tccacgtagg ctattttttt
    19141 acggactgag tttaccgact gtccagaaaa ggtgacttta ccagtagtag ctggtatcaa
    19201 ctctagcaaa gatttcataa atgttgattt tcctgcaccg tttggtccga taataccggt
    19261 aattttttgt ggatttatcg tcaagttgat agttttcaaa acagttttcc cttgataagc
    19321 ggctgaaagg tcttgaatta caatggccgt acgttccaaa tcttacactc ctttttaggt
    19381 ttacctaact ttttatttaa atatagttta actaaaatgg aaagcatttt caagtagaat
    19441 gatgaaaaag tttttttcga attttcctcg cattttatga aaattttctg tagaatcaca
    19501 tcaagagttc aataaggcta acctaataat gaaaaacatg tgttgaaacg tttgattatt
    19561 ttttcttgtt gactcaacaa cgaaaggagt ttttgtatgg aagaagaaaa gttaactcga
    19621 agtcttagtg cccgtcatat ccaaatgatc gcactaggtg gaacgatcgg tgtcggtctg
    19681 tttatgggtg cctcctcaac catacgttgg acagggccct cagtgatggg agcctatgcg
    19741 attgcaggat tctttttgta tttgattatg cgtgctttag gcgaaatgct ttacgttgat
    19801 ccttcgactg gttcttttgc aaattacgcg agcgagtaca tccatcctgt ggctggctac
    19861 ttgaccgctt ggagtaatat ttttcaatat attgtcgtag gaataagtga agtgattgct
    19921 gtaggatctt atatgaatta ttggtggcct gatttgccgg caattattcc cggaatcatt
    19981 gtcgtcttgt ttcttatgct ggcaaatctt atttctgtca aggcgtttgg cgaattagaa
    20041 ttttggtttt cgatcatcaa agtcataacg atcattttga tgatcattgc aggtcttggg
    20101 gtaatcttat ttggatttgg taatcatggt caggcagtag ggatttcaaa tctttggaaa
    20161 aatggtggat tcttcactgg aggcgtcaaa ggatttttct ttgcattatc gatcgttgtt
    20221 gcttcctatc aaggaatcga actgatcgga atgactgctg gtgaagcaga gaatcctaaa
    20281 aagacgatca ttgaagctgt ccagtccact atcggtcgaa tcttgatttt ttatattggt
    20341 gctattttta tcattgtgag tatctatccg tggaatcaat tgagtgagat tggttcacct
    20401 tttgtacaaa ctttttctaa agtcggcatt acatttgctg caggactgat taattttgtc
    20461 gtgattacag cggcattatc aggttgcaat tcagggattt tcagcgcaag tcgtatggtc
    20521 tatacacttg ccataaatgg aaagatgtct aaaaaatttc tgaaactatc tcgtcacggt
    20581 gcgccttttt atcctgtcgt agcaatctca ggtggaatct taattggtct gatcttaaat
    20641 tatcttctac caatgttcat caaccagtca gaaaatattt tcgttttcgt atacagctca
    20701 agtattttgc ctggtatggt tccttgggta gtgattttga tcagcgagat tcgcttcaaa
    20761 aagaagcacg cagataaaat gcatgatcat ccttttaaaa tgccactatc tccttatacg
    20821 aattatgtga cacttgcttt tttagctatc gtattgattt tcatgtttat caatcctgaa
    20881 acgagaatct cattgattat tggactcgtt ttcttgcttt acatgacgat ccattacttt
    20941 gtacgcgaaa aaagaaccgg aaaataaaaa aagaacgaag cttcacctta gtggaagctt
    21001 cgttcttttt tattgctttt atcaattcaa ttttagcgtc tcaccgggag tcaggaaata
    21061 attctccatg ctcatcccat tcagcgacaa gatcgtttct actggtacgc cagttcgttc
    21121 ggctatttga tttggacctt ctccttccaa aactacggtt gtcgcagcct gtgaagtcgc
    21181 gctgttggta ttagtttcag aggaatctgt tgtgtcttgt gttgttcgag cttgcatttc
    21241 agaagcttct accgactctg ctgtctcaga atcagaagat gttgtgtctt gtgtgcttgt
    21301 tgactctgct tgaagagagg cgctagtctg caaataaata tcggaaatct tagcgacatg
    21361 attcgtataa ttagccgata attgattgat caaagtatct aagtctacac cgtctttatt
    21421 ttctgctgcc tgatacgctg cacgtaattt tctgatccct tcgtcggaga ttgcttgaag
    21481 ctcacgtgct ttttggttag caactgctga taaaccagct attccctctt gatttccctg
    21541 aatttctgtc tggtattctt caatcaatgc aggcgtcttt tcttcgatct ttttcgaata
    21601 atcatttacg attgcttgaa gttgctctgg caaaccattt gctgtttttt cttcagaagt
    21661 ttgtgtctct tttgttttag ttgatgactc acttgtttgt ttcgtctctg ttttctttgt
    21721 cgttgtttcc gttatggtcg tacttttcgc ttctgacgaa ttttttccat gaaaatatag
    21781 acccgcaact cctcctgcta tgatcaaaaa cacggcaact gctgccccaa tcatgatcat
    21841 ccgcttacga gctgcctgtt tttgctgtct tcttcgggtc atccgaacat tttctcccca
    21901 ctcattttca tcatacattt ttttcaccac caatttttat gtataatagc gttatcaaac
    21961 gcttcatatt cttattgtag caaataattg tcgctgtgca catttttatc tttgttattt
    22021 ataagaaaat ttcaccagtt gagatgattc caagattgtc cgtcgatttc tccttgcagc
    22081 tgcattgttc gttcgtctat ctcagccatc agtttcttta tttcatataa gagcgcacgg
    22141 tcttgatatt ctgatttttc gcttaattca tctaattgtt ggatcagcca atcatttgtc
    22201 ataatgaagt tcctttcatt tcttgcagtg taaaggtcaa gtcttcgatc tgctcttttg
    22261 cctcagtcag tgcttctacg atatatgctt gtttttcaga ttcttcttcc tgcattttct
    22321 gattttcctg tactctttga ataaaccagt caatccgctg agtcagcgat ggtttgcctt
    22381 ccaatgagag atactgctga taagcaatta gcttctccca acgtttttcc tgggataaat
    22441 acataaattg tgctaaaacg aatggcggaa gataggtcat atggaattta tttgcgattc
    22501 gctgatacgg cctcaaaaat tcggaaatcg tatattcttc ttttcctcca gcttggtatt
    22561 ctttttccgc cacacctgtt gtcaatacga ttcctagttc tttccctttt aatacatgtg
    22621 ctgctcgttc caagacatta tcttgccaaa tttttaaatg agcaggagaa ctataccagt
    22681 aaaacggaaa ctggaaaatg atccgatcat gctgggccaa gagctgtagt tcagtctcta
    22741 tatctatttt tccgtctgga taacttgatt ccaaatgatg ccaagtagct ggtaaaccag
    22801 cagaagcttc tttgaaaaat tgctgattta aagattcttc gatcgttgga tggctaatga
    22861 tgataagtgt acgcatccct tttcctcctt tttagtcttc gctttacagt gtagcataac
    22921 cgccacaagt ttcttttgcc gatgcttgtc attttaacca gactaatcag gttgtccaag
    22981 aaactgcggt ttgtttttcc aactgttttt tcaaggtatc caaagcaata ttcttaaaat
    23041 tttcgttttt catacgttta cgatagttcg tagccgtttc tccggtactc tttttgaaca
    23101 ttcggctaaa tacgactaga ctattgaacc ctacttgata ggcaatactt tccacggatt
    23161 catccgtcag agaaagaaga aacgcccctc gattgatccg taccccgatc aaatattcct
    23221 tgatactggt acccatatga tttttgaata ctcgcgacaa atggctccga ttgaccgcta
    23281 aatgctgggc gatttcctca acagacaatt tttcagcata atgtgcctcg atgtatttga
    23341 ctgtttcaac agctaaagag gaatgaacct tttgtacacc accgctgacc tttccgccat
    23401 cttttaaaag gactgataaa aaacggtagg ttaatgctgt taactgtaat tcattttcca
    23461 aggtttcttc cgtatctttc atgcattcta aaataatgtc gatatatttt tgtatgtcag
    23521 aagagaccat cgtgtattgg tcttctctga aaagcgactg ccgaatgatt tcttctgcag
    23581 cactcccacc aaatgaaagc cagcaataca tccacggatc ttctccatct gataagtaaa
    23641 acgtcgagtc tcctggacga atcaagaaca gatcaccttt tttcaattgg aattgttgat
    23701 ttttcacatg ataagatcct ttgccttcca tcacgacatg caggatgtaa tcattgcgaa
    23761 tagcaggacc aaaagaatga aacggcatcg ttttagagaa accacaaaaa tcaaaataca
    23821 attctttttc tacttgttga tgttcctttt ttaaaaaaat cgattgctcc acgtctatcc
    23881 ctccttactc ctttagtata atgcaacaaa aagttaaata aaagtcacag aaatatatta
    23941 aaaaggaagc gatttcttgt taagtttaag tcattaaaag atctttgtta ttcgttgtaa
    24001 ccggtttact tagtattata tattgaacag gagaggaata cagattatga aaagcaaaat
    24061 gatccaacgt gtgtcctacg ctttaggcgc ttttggacac gacacattct atgttacatt
    24121 aagcacttat tttatggtat tcgtgacaag ccagatgttc gcaggaacag ataaggcaac
    24181 gaatgcaaaa atgattgcta cagttacaag cttagttgta ggtatccgct tagttgaaat
    24241 tatttttgat cctttgattg gtggcatcat cgataatact cgtacaaaat acggtaaatt
    24301 caaaccatgg ttagttatcg gcggcgttgt tagttccgta ctcttggtag caatctttac
    24361 caatttcttt ggcttagcta ctcataatac gactttattt atcatattat ttgcaatcgt
    24421 tttcatctta ttggatagtt tttattcatt taaggatatc gctttttggt caatgattcc
    24481 agctttgagt acggaaacaa aggaacgtga aaaatttgct acgtttgctc gtttcggctc
    24541 ttctctaggt gcaaatggta ctactctagt cgttgtccct atcgttactt tctttaccta
    24601 tcttgttact cataaacata ttgaaggcgc ttcaggctgg ttctggttcg gtgtgattgc
    24661 tgctgttatt tcaggcggta ctgcgattat cactgccttg ggcacaaaag aagtcgatac
    24721 tgcgatccgt cagcaaaatg aaaaagctgg gatcaaagat gtgttcaaag cagttgctca
    24781 aaatgatcag ttgatgtggc ttgcccttgc ttatatcgct tatgcgattg ccaatgcagc
    24841 aacaactgcc gtattattct acttcttcaa atatgtactt ggccaaccaa ctgaattttg
    24901 gatcgttggt ctagttgctg ccttacttgg tttagtagct gttccactat tcccaatgct
    24961 tacacgcgtc atctctcgtc gctacgttta ccttggaggg atcgcaatga tgatttcttc
    25021 ttactttttc tttacgatcg caggttcaag tttgccaatc gttatcatcg ggctagtatt
    25081 gttctacttc cctcaacaat tgattttctt atccgctttg atgacgatca cagactctgt
    25141 tgaatatggt caatggaaaa atggtatccg taacgaagct gttactctat caattcgccc
    25201 tttactagat aaaatcgctg gtgctttgtc taacgggatc gtagggtttg tcgctatcgc
    25261 ttctgggatg actggtaatg ctactgctgc tgatatcact gctcatggcg taacgacttt
    25321 caaagcttat gcattctatg ctcctgctgc tttgatgatt ttctccgcta ttatttttgc
    25381 ttggaagatt acattgacag agaaaaaaca tgcacaaatc gttgagaaat tggaaaacaa
    25441 attggctcca gctgatacaa tggaagatga acttcacgat gcagtagatc cttcccatta
    25501 agaaaggatc ttgaaaatga agattacaga aaaagatttt ggccaaggtt atcacttgat
    25561 aaccttggag aacaaaaaca agctagcact ttctatctct gatttaggtg ctagaatcgt
    25621 cagtttaaaa tcaaatgatc gagaattagt tttgggattt gacaccgctg aagaatatat
    25681 cgaaaaagat ccgtatatcg gtgcttctat cggtcgcacc gcagggagaa tcgaaaatgg
    25741 ccgcttttct ctcaatggaa aaacttacca attagccaca gatccaaaaa ctggacataa
    25801 tctgcatggt ggtgctcctg gatttgaatt aaaaaaatgg tcttatgtca ttttgaatgg
    25861 cgaaaatgaa gcttctgtca tttttactac tacaagtccc gacggagaac atggttttcc
    25921 aggtacaatg gatgtggaaa tccgctatac tttgacaaaa gataatatct ggcgagtgac
    25981 ctctcgcggc accagtgacc aagatacttt attcaatccg acaaatcatg tttacttcaa
    26041 cttgacggga gatgcttctc agtcaatcga tcaacatgag ctttggctca atagcgaagc
    26101 ttatgctcct ttgcgaacag atagtattcc tataggggta aaagaaaatg ctgcaggaag
    26161 tgctttcgat tttcaaatac ctaaaaaatt agcgtccgtt tttgctagtg atttggatca
    26221 aaaaaatctt gttgacggaa tcgatcatcc atttttctta aaagaaaccg gcttgggtaa
    26281 agaagccgct cgcttgacta gccccgataa aagaatccaa gtagatattg ctacagatgc
    26341 ttctagtgtg gttattttca ctgcaaattt cggcacagaa acaccagaaa tgcgcaaccg
    26401 aaaactggca catcacggtg gcatcacatt tgagactcaa acagctccag gtgcagagcg
    26461 cttctcagca tttggttcga ttcatttaaa agccggatca gtatttgaaa cagtaacaga
    26521 attcaaaatc aaaacaagaa aggaataact catcatggaa atcaaaagaa gcttaaacac
    26581 aaaatttgcc gaaacattcg gacctaaaaa aactacacaa tacttctcac caggacgcat
    26641 caatttgatt ggtgaacaca cagattacaa tggaggccat gtcttccccg cttccatcac
    26701 ttatggaacg caaggtgtag cagcacctcg agacgataat aaaatattag tttattccac
    26761 aaactttgac gatatcggtg tcattagttt tactttagat gagctagaat atgataaaaa
    26821 agcaaactgg gcaaattacg taaaaggaat ggtccttaaa ttaaaagaag ctggacactc
    26881 aatcgatcat gggtttgagt tattagtgga aggaacaatc cctaatggtg caggactttc
    26941 cagtagcgct tcattagaat tattagtagg tgttgtatta gaagatctgt ttgatttaaa
    27001 aacagatcgc ttggaactag tccaaacagg taaaaaagta gaaaatgaat tcatcggtgt
    27061 caattcaggt atcatggatc agtttgccat cggcttcggt gagctagatc atgcaatctt
    27121 attagataca aatacgctga aatacgaaat ggttccagtg aaactagatg gttatgcaat
    27181 cgtcatcatg aatacgaata agcggcggga attggcagat tcaaaataca atgaacgccg
    27241 tagcgaatgc gaagaagcct tggcacgttt gcaaaaaact ttgcctatct cttctttagg
    27301 agacttagat gaagaagaat ttgaatcaac tattgaccaa atcggcgatg atacattgat
    27361 acgcagagct cgccatgccg tttctgaaaa tcagcggact ttgaaggcaa aagctgaatt
    27421 agaagctggg aacttagaag catttggtca actgttaaat gattctcacc actctcttcg
    27481 ctatgattat gaagtaactg ggatcgaatt agatacacta gtagatgctg ctcaaaaaca
    27541 agaaggtgtc ttaggtgcac gaatgacagg agctggattt ggtggctgtg cgattgctct
    27601 tgtcaaagaa gaaaatatac ctgccttcaa aaacaatgtc tatgatgaat acatgaaagt
    27661 tgtcggctat gctccggaat tttatgttgc acacattgga aatgggacaa caaagatcga
    27721 tccagaagct gttcatgttt gataaaaaaa tcaacgatct cagctaaaaa caaatagata
    27781 aaaataacct ctcagcaatt tccaaatgtg agccttttgc tcgtatttga aaattgctgt
    27841 tttttattga cacggaaaga gaacgtgtgt tctaattgtg ttgaagaggt gattgttatg
    27901 tgggcgaatc aaaatccggt atttgtttat gaaaaagaac cttcaagaga tattttatgt
    27961 attgactgca aatcttttta cgcctccgta gagtgcgttg aaaaggatct tgatcccctt
    28021 acaactaaat tagtagtcat gtcctatccg tccgattcga cagaaacacg gggtagcgga
    28081 ttaatcttgg cttccagtcc tgcagcaaaa aaagcttacg gcatcaccaa tatcagccgt
    28141 gccagagatc ttcccttccc ctatccaagt gatttatata ttgttgcccc aaggatggcc
    28201 tattatatgg aaaagaacag agaaatcaat tctatctata aaaaatatgc agacgaagcg
    28261 aaccatcatg tctattccgt cgatgaaagc ttccttgatg taacaaatag catggcactc
    28321 tttggtaaaa caaatgcgta cgacatggct aaactgatcc ataaagatgt gtttgagcag
    28381 accggaatct acacgactat aggaattggc gataacccgc tacttgctaa actagcctta
    28441 gacaatggct caaaagacgg aaagcaaatg tttgctgaat ggcgttatga agatgtacca
    28501 gaaaagttat ggaaaatctc agatatcact gacttttggg gaatcggcaa acgaacagca
    28561 aaacgtctga aacaaatggg tatacattct gtttatgatt tagctcacgc ggattattat
    28621 cacttgaaaa gcaagctagg ggtcatcggt actcagcttt atgcccatgc ttggggcatc
    28681 gatcgaagtt ttttgggaca agaatataca ccaaaatcaa aaagtatcgg aaatagtcaa
    28741 atcctagata gagattatac aagacgagaa gaaatcgaga tcgttatcaa agaaatggcc
    28801 gaccaagtcg gcactcgctt gagacgatct gcagcaaaaa cacaagtagt cagcttatgg
    28861 gtaggatact ctttaggcta tcttgatcca aatggcaaga ccgggtttca ccagcaaatg
    28921 aaaatcgaag cgacaaatgc tagcagagat ctagcagatg ctttattgac cattttccac
    28981 cagcattacc actaccagga tattcggcgt gtaggcgtga actgttccga cctcgtatac
    29041 gcgacaggtt tacagcttaa cctttttgaa gatcctgaaa agcagataaa tgaagcgaaa
    29101 gttgattttg ttgtcgatac gattagaaaa aaatacggct ttcaatcaat catccatgcg
    29161 catagtctct tgcaaggagg acgcgccatc gcacgtagtt ctctcgttgg cgggcatgca
    29221 ggtggtatga gtggattaga aggtggaaaa gatgagacgg acagcaaaaa aattcattga
    29281 ctataacgag tatcgagatc ggccatttgg attaaaatgg gggactgctt ttgcgatgga
    29341 agaactagtc aacggtatca aaaaaatgaa gaagaagcac gcaaacagcc tcttcctaaa
    29401 caacaaatga cattgcaaga aatcgatagt atactgacag aagccttttt atctcgtaaa
    29461 gcagtaatca ttcagctcaa tttaaaagat gaatttggaa gactcttgga tgaggtcgaa
    29521 gggcacttca ttggtgaagc ctatgaagat tactttatga ttgaccatca gccgatattg
    29581 tgggaagacg tacggtatat tgagttaaag gaaacaaaaa aatggtttgt gacatgagag
    29641 gttgtgacag aagtgatcaa cttcaaaaaa taagaaagga tttttcgaaa attgcttctt
    29701 aaatttttgt ggaattttgg cttatttttc gaagaagcaa cttctggaac aacgtatatt
    29761 agatatcaga ggttgtgaaa aagtcgctta gttttgagta acaagccaag gcgctgattt
    29821 cacaacctct gtctatctat ccatctattc ggtaagattc atgcatgacg tcttctttat
    29881 ttagtatgta gagccctttt tcttctgacc attcaacata aatcagctgt tttacatctg
    29941 catagccttc tttcttcaag ttctccataa gccatgcttc agtcaattga ttggactgaa
    30001 gcactttatg ctgaatttgc ccttcatcta caagcaggat cgataaagct ttgtcttcat
    30061 ctgatttttt caatacactc atttgaccgg cattctctag gataacatgt ttggcatttt
    30121 caagaaaaaa gcattcttgc tgtcttaaga ttgctcgcaa ctgctccatc tcgatatggt
    30181 tatttgtcaa ctctgtcatg ttgatgacgc cgtctttgat tagaacagat ggctcgcctt
    30241 tgacccaacg attgaccttt tcattttttt ggacgatacg ttcgatacca taaatcatta
    30301 ctgcccaaag cgcaatggca aataggacat gccctacatg gacattgtca tcataggttg
    30361 attcttctaa gatcccacct aaaacaagcg tatagactaa atcaaacggt gtgatttctg
    30421 acatggattt cttcccaagc aaacgtacca ctaataataa accgatcaac ccgaacacca
    30481 gtttcattgt aattgaaaaa atcatttttt ctccccctaa ctatctgtta attaaattat
    30541 atatgctttc tcacgaacac gcatggaata tacaaggaag aaatgtatcc ttttactaaa
    30601 aaaaggactg tgacactgta gtgaccccca aaagttagac ttttttggag tggagaaatc
    30661 cactcctttt ttttatgctc taaaatgata tttttacaca accgttacgg ttgttttacg
    30721 aaattggacg
//
LOCUS       DAZKCH010000028        30640 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000028 DAZKCH010000000
VERSION     DAZKCH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.028"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            265..2031
                     /locus_tag="ACG84X_001283"
     CDS             265..2031
                     /locus_tag="ACG84X_001283"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFP9127170.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            2133..3392
                     /locus_tag="ACG84X_001284"
     CDS             2133..3392
                     /locus_tag="ACG84X_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFP9127171.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3539..4840
                     /locus_tag="ACG84X_001285"
     CDS             3539..4840
                     /locus_tag="ACG84X_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127172.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4843..5694
                     /locus_tag="ACG84X_001286"
     CDS             4843..5694
                     /locus_tag="ACG84X_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFP9127173.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5707..6522
                     /locus_tag="ACG84X_001287"
     CDS             5707..6522
                     /locus_tag="ACG84X_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFP9127174.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            6673..7839
                     /locus_tag="ACG84X_001288"
     CDS             6673..7839
                     /locus_tag="ACG84X_001288"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9127175.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            8069..8716
                     /locus_tag="ACG84X_001289"
     CDS             8069..8716
                     /locus_tag="ACG84X_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFP9127176.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            8800..9744
                     /locus_tag="ACG84X_001290"
     CDS             8800..9744
                     /locus_tag="ACG84X_001290"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFP9127177.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGV
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            9879..11330
                     /locus_tag="ACG84X_001291"
     CDS             9879..11330
                     /locus_tag="ACG84X_001291"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFP9127178.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            11351..12187
                     /locus_tag="ACG84X_001292"
     CDS             11351..12187
                     /locus_tag="ACG84X_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFP9127179.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            12187..12846
                     /locus_tag="ACG84X_001293"
     CDS             12187..12846
                     /locus_tag="ACG84X_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFP9127180.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            12972..13661
                     /locus_tag="ACG84X_001294"
     CDS             12972..13661
                     /locus_tag="ACG84X_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127181.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            13667..14623
                     /locus_tag="ACG84X_001295"
     CDS             13667..14623
                     /locus_tag="ACG84X_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFP9127182.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            14667..15179
                     /locus_tag="ACG84X_001296"
     CDS             14667..15179
                     /locus_tag="ACG84X_001296"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9127183.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(15435..15983)
                     /locus_tag="ACG84X_001297"
     CDS             complement(15435..15983)
                     /locus_tag="ACG84X_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFP9127184.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(16072..17253)
                     /locus_tag="ACG84X_001298"
     CDS             complement(16072..17253)
                     /locus_tag="ACG84X_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFP9127185.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(17489..18997)
                     /locus_tag="ACG84X_001299"
     CDS             complement(17489..18997)
                     /locus_tag="ACG84X_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFP9127186.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            19156..19347
                     /locus_tag="ACG84X_001300"
     CDS             19156..19347
                     /locus_tag="ACG84X_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127187.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            19550..20467
                     /locus_tag="ACG84X_001301"
     CDS             19550..20467
                     /locus_tag="ACG84X_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFP9127188.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            20460..21533
                     /locus_tag="ACG84X_001302"
     CDS             20460..21533
                     /locus_tag="ACG84X_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127189.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            21681..22199
                     /locus_tag="ACG84X_001303"
     CDS             21681..22199
                     /locus_tag="ACG84X_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127190.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            22180..22572
                     /locus_tag="ACG84X_001304"
     CDS             22180..22572
                     /locus_tag="ACG84X_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFP9127191.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            22648..23583
                     /locus_tag="ACG84X_001305"
     CDS             22648..23583
                     /locus_tag="ACG84X_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFP9127192.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            23716..24495
                     /locus_tag="ACG84X_001306"
     CDS             23716..24495
                     /locus_tag="ACG84X_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFP9127193.1"
                     /translation="MNKKKSAPWLQALHAVMPLYISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            24488..24805
                     /locus_tag="ACG84X_001307"
     CDS             24488..24805
                     /locus_tag="ACG84X_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFP9127194.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            25049..26659
                     /locus_tag="ACG84X_001308"
     CDS             25049..26659
                     /locus_tag="ACG84X_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFP9127195.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            26816..27664
                     /locus_tag="ACG84X_001309"
     CDS             26816..27664
                     /locus_tag="ACG84X_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFP9127196.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            27895..28374
                     /locus_tag="ACG84X_001310"
     CDS             27895..28374
                     /locus_tag="ACG84X_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFP9127197.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            28407..30635
                     /locus_tag="ACG84X_001311"
     CDS             28407..30635
                     /locus_tag="ACG84X_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9127198.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
BASE COUNT        10052 a         5422 c         6171 g         8995 t
ORIGIN      
        1 atatacttct acgttaaaaa ctgttaaaaa acttttactt tagaaaattg gagaaattga
       61 tcgcttaaga taaattcagg acactaaata gtacaggaag tagattaaaa cttttaaaag
      121 ttttaagtct atctatttgg caagtttaaa aaataaaaat tcggtatcaa aaaactgtta
      181 ccgataacat ttttgaaagc gttgtctttt gtttctctat cacttatagt gatgacgtca
      241 tattaaaaca caaggaggaa atcaatggat acagctgcaa tttatcatcg accggaaagt
      301 gaatatgcat ttctatatac gaatacaaga tttcgtattc ggcttcgtac taggaaaaat
      361 gatatcaaaa aagtatatgt gctttgtgga gatccatata ccataacaac tgaaaaatgg
      421 tatcaaaaac aacgaccaat gaaaaaatgt ctaagtacca atgttcatga ttattgggaa
      481 attgaagtga cgagcgaaac aaggcgctta cagtatgcgt tccatgttgt tggggaagat
      541 aacacggact gtttttacgg tgatcaagga atttttcctt atcgagaaaa tgtgattact
      601 gaaccaaatt tttattttcg aataccttat tttcatcaaa tcgatcgatt cactattcca
      661 gaatgggtaa aagaaacagt atggtatcaa atttttcccg aaagatttgc aaacggggac
      721 aaagcaaatg accccgaaca cactttacct tggggaagta aagatccaga ccgagaagac
      781 ttcttcgggg gagatttgca aggtgtgagg gatcatttgg attacttgac ggaccttggc
      841 gtcaatggca tctatttttg tcccatattt aaagccacat ccaatcataa atacgatacg
      901 attgattatt atgaggtgga tcccgctttt ggcgataaaa aacttttaaa aaacttgatt
      961 gatgaagcac ataaaagagg gatacgtatc atgttcgatg ctgtattcaa tcatatgggt
     1021 gtccattcac cacagtggca agacgttctc aaaaacggag aaaaatcgat ctataaagac
     1081 tggttccaca tccgtttttt cccagtagat tcttatcaga tgactgactt accagaaact
     1141 gctgaaaata tcccatatga tacttttgct tttactccat tcatgccgaa actaaataca
     1201 gcaaatccag aagtgcaaaa atatttgctg gatatcgcaa cttattggat aaaagaattc
     1261 gatattgatg gatggcgtct tgatgttgct aatgaagtcg atcatcattt ttggaaaaaa
     1321 ttcagagaag cagttacaga aatcaaacca gacatctata tccttggaga gatttggcat
     1381 tcctctcaag cttggctgca aggggatgaa ttccatgcag tgatgaatta tgcattcaca
     1441 gattcgatta aagattattt tgcaaaaaag aaaatcacag cttcacaaat ggtcagtgga
     1501 atgaatcatc agcaaatgct ttacagagat caggtgaacg aaggaacatt caacttatta
     1561 gattctcatg atactgccag gatcttgacc ctttgccaag gtaacaaaga attgatgaag
     1621 tctgtgatgg cctttatgtt tcttcaaaaa gggtctcctt gtatctatta cgggacagaa
     1681 atagggatga ctggtgaaga tgacccggat tgccgcaaat gtatgatatg ggagaaggag
     1741 gaacaagatc tagagctatt cggttttata aaagaacttg tttctctaag gaaacagttg
     1801 tctaagatta tttctgaagg ttctactcag tggctaatag tatatgatcg tgaagataag
     1861 ctctatttca cacgggaact agagggacag atcatctatg tttactttaa tcagtcaaaa
     1921 gaaccttggg tagtagaaca ggaaaatgag gtgattctta gtcaaaattg tcagttgtta
     1981 gaagacggga aagcagagat acgacaatac ggatttttga tcatgtgttg aaaactgtta
     2041 ccggtaacaa caagaaagcg tttgcaaatg aagatttgtg cccattataa taagggtgta
     2101 acagcacgtt gaatacacag gaggaaatga agatgaaaaa aagaagtgtg aaacagttgg
     2161 gtttagggtt aatctcttta ggaatcttag gcggattagc ggcttgtggc aatggtaact
     2221 cttcagcaga aggggaagcc gatgaaggaa aaacgttaac agtttccgtt gattctggat
     2281 ataaagatta tataaacgaa ataaaaaaca ctttcgaaaa agaaaacgat gtgaaaatca
     2341 agctagtaga aaaggacatg ttcgatcagt tggaatcatt agcgttagat gggcctgctg
     2401 gaaagggacc tgacgttatg atggcagcat atgaccggat cggtgcgtta ggacagcaag
     2461 gacatctggc ggaagtaaaa ctgggaaatg aagcagctta cgatgaaaca gacaaagccc
     2521 aagtgactta tgatggaaaa atctacggag aacctgcagt aatcgagacc cttgttttgt
     2581 actataacaa agatttagtc gatacagcac catcaacgtt taaagatttg gagaatctat
     2641 ccaaagacag tcgttttgct tttgagtcag aagcaggaaa aaatacagga tttttagcta
     2701 aatggactga cttttattat tcctatggtt taattgcagg ttacggtggc tatgtatttg
     2761 gtgatgatgg cacaaatcct tcagatatcg gtttgaataa tgcaggtgct gtagaaggaa
     2821 tctcttatgc aacagattgg ttcaaaaatg tttggccaaa gggaatgcaa gacataaaaa
     2881 gtgcaggaga cttcgccagc cagcaattca tgtccaataa aactgcagca atcattgacg
     2941 gtccatggca agcgcaaaca tacaaagaaa acaatatcaa ttatggtgta gccaaaattc
     3001 ctactctaaa taatggacag ccttatcaac cgtttggcgg aggaaaagga tgggtagtca
     3061 gcaattatgc taaaaacaaa gacctctctc aaaaatggct tgattatgta acgaatcagg
     3121 aaaatcaaga aaaattcttt gaaatggtaa atgaaatccc tgcaaaccaa caagctaggg
     3181 aaacagcaaa ggctaaaaac gatgaattaa caacagctgt gattgaacaa tatgaaacag
     3241 ctcaagcgat gccaaacatc ccagaaatgg gcgaagtttg gacaggtgca gaaaacttga
     3301 tgttcgatgc agcatcaggt tcaaaaacac caaaagaatc cgcagatgaa gcagtaaaaa
     3361 caatcagtga agccatagaa caaaaatact gattaaaatg ataaccgtcc atttttataa
     3421 aaaatggaac aggtgcttca gataaaagtg gcaagagcga gatggaaaat tatcttgctc
     3481 ttgttgccat tatcttaaaa gcagtttgcg gtttagcaag tttagagggg gcattcagat
     3541 gcagcaagat aaaacaagca atatcaacga aaaaaaaatc acgctttgtt cacttattcc
     3601 agggatgggg cagtttgtaa atggccaagc ttttaaaggt atcgtttttt tcgccatatt
     3661 cgtcctattc attggtcaga tgcttctggg cggatttcat gcattggtag gattggttac
     3721 tttgggaagt ataccaatgg aagatcattc attatttatt ttgattgaag gcactttgca
     3781 attcatcatt acaatcattt tcttgatttt ttacggtttg aatcttttag acgcttatcg
     3841 agtagcgaag atgcgtcaag agggcaaaaa aatcaatcgg acgatgaagg aagtcataca
     3901 taatataggt gatgaaggtt ttccttatct attgacactt cccgcttatc ttctcatgat
     3961 ttttacgatc attttcccag tcctagttac attgttcact gcatttacta attatgactt
     4021 caatcatatt ccaccagcca gtttaattga ttgggtaggg gctaaaaact tttttagtat
     4081 cttcttttta agctcatatc gtaatacttt ttttgcagtc ttttcgtgga ccgtgatttg
     4141 gactttatgt gcaacaactt tgcaaatcac ccttggtatt ctcacagcgg ttgttgctca
     4201 ccagaaattt attaaattca aacgtatttt cggtatcatt ttcttattac catgggcggt
     4261 cccagctttt attactatca tgagtttttc gaatatattc aacgatagcg taggtgccat
     4321 caatactcaa gtgattcctt tcataaacca gcttcctttt gtagatatca gtgcaatctc
     4381 ttggaaaacg gacccgaact ggacgaaagt agcaattatc ttagtgcagg gctggttagg
     4441 atttccctat atctatgtga tggttacagg aatcttacaa tcgatttcag aagacttata
     4501 tgaagcagca aaaatcgacg gagcaaatgc atggcagcgc ttttcaaaca tcacgcttcc
     4561 tgctgtcttc ctagtggcag cgccaacatt tattacacag tatacgggga atttcaataa
     4621 tttctccatg atctatctgt ttaacaatgg tggtcccgga agcgtaggcg gaggagctgg
     4681 ttctactgat attcttattt cctggatcta taaacttacg actggaactt ctccgcagta
     4741 ttctatggct tcagcaatca cgttgattat ctccgtcatc gttatctgtg tgtcattgct
     4801 ggtatttaaa aagacaaatg cgttcaatat gggggattaa caatgaaaaa atttcattcg
     4861 agtgctcgat tccaaaaacg actttctcac ttttttactt acttttttct tttaatactg
     4921 tcagtcatta tcatctatcc gcttttgatc acagcaagta ctgccttcaa gtcaggaaat
     4981 attgcagctt ttagtttaga tctttcaagt gactggactt taggaaactt tactcggcta
     5041 ttcagtgaaa cactttacgg gacttggtat aaaaatacat tgatcatttc tgtcctaaca
     5101 atgatcgtac aagtgactgt agtaactttg gcgggctata cttatagtcg ctatcgtttt
     5161 atcggccgca aatcaagttt gatgttcttt ttagtgattc agatggtacc gactatggca
     5221 gcattgactg ccttttatgt catggctttc ttattagaag cgctcgataa gtactggttc
     5281 ttgacaatga tctatatagg cggtggaatt ccaatgaata cttggctgat gaaaggatac
     5341 tttgacactg taccaataga tttagatgaa tctgctaaac ttgatggggc agggcatttc
     5401 aggatttttt tccagattgt attaccgctt gtcaaaccga tgctcgccgt tcaagcatta
     5461 tgggctttta tgggaccttt tggggatttc atgttagcta agttcctgct tcgaacacct
     5521 gaaaatcaga ctgttgctgt cggcttacaa acatttattt ctgatgtgac aaaccaaaga
     5581 gtctctcttt ttgctgctgg ggcaattttg attgcactac cgatttgtct attattcttc
     5641 tttttacaaa agaactttgt taccggcctg acatctggcg gaacaaaagg ataggagcag
     5701 agtatcatgc aaacatttcc gttaaactat ttttccgcat tacgtacgcc aactcaagtg
     5761 tttgcgggac gcaaactatt atcatggcct aaatttttct tgatatttgt atttttagtt
     5821 tccttgatgg tcatgcctgt gactcttttt tatgccaatc agatccaagc gattccatta
     5881 gaacaatttc tatccgttca ttcgctgatc gatgaacaag gaacccaaaa attttctgaa
     5941 cttgaattat ctgaaactgg gttacaagca tcgcaacaaa cgatagctgt gacccctgaa
     6001 attttggtag gtgtgtcttt atctgagaaa caacaatccg atcatggaac ttttattgat
     6061 tttgagaagg aacaatgggt gatccaacaa aaggataaat ctggtatacg ccgctatacg
     6121 atgaattata gcccatcttt ccaaccagat tctgtacgta cgcccgaaga tttccaacga
     6181 tttttagaaa gagaatttta tgccagtaat cgtccaacaa tcattttatc ttatagttta
     6241 agtcttggtc ttgtcctatt tgtcatgacg agtctcattt tattcggggc ttcctttttc
     6301 ttgtggatga caagaaaaag ccaactttca tccattcata cattcaaaga gagtgcaaat
     6361 ttgatgctga atgttatggg aataggttcc atggcagcag cagttgtagg gtttatccac
     6421 tttgacttta tcttgatgct aagtgtccaa acaacgataa ctgtcttgct gcttttatgg
     6481 gtttttgtca aaacaagatt caaagataag cgtgtcgaat gacaagttta agcgatttat
     6541 gcgacaatga atgtgaaaaa aatgaaaaat aaagtagttt ttgaaaaatt tctgaaaaaa
     6601 ttaaacttct tagttgattc ttttcttttt tagtattaac gtaatagggt agttttttta
     6661 aggaggaaaa tcatgttaga gaaaacttta tacaatcaat tattttcacg ttctttctcg
     6721 ctccctgtcg aagtaaatta ttgggacggt acaacgaaac aatacggaga tacggacact
     6781 cctccccaaa tcaaaatcaa tatccatgaa gaaatcccaa tgaaagagat tacaagtaac
     6841 gcttctttgg cactaggaga agcctatatg gatcatcgaa tcgagatcga gggaagtatc
     6901 caagcattga tcaacgatgc ttatcagcaa gcaaacagct ttttacgagg aaaagattat
     6961 ctaaaatggc tgccaaagaa agaaaaacat acgaaacaaa aaaacaaaga agatatccat
     7021 gcgcattatg acttaggtaa cgacttttat aaactttggc tagatccaac tttgacttat
     7081 tcttgtgctt atttcaatac acctgaagat acgttggaac aagcacaaat caataaagtc
     7141 catcatatct tagacaaact ctttatcaaa gaaggcgaaa cgttgcttga tatcggttgt
     7201 ggctggggaa cattgatgtt cactgctacc aaagagtata atgtcaaggc aactgggatc
     7261 acactaagtg aagaacaata cgatttgatt accaaaagaa taaaagaaga acatttagaa
     7321 gataaatgcc gtgtattatt aatggattac cgcgaactaa aaggcgaaac gtttgatcat
     7381 atcacaagtg taggtatgtt cgaacatgta ggttctgaaa atcttgaagg ttatttcaaa
     7441 gtggtaaaag atttattgaa accaaaagga acagctttga tccatggaat cagccgacaa
     7501 caaggcggtg cgacaaatgc ttggatcaat aaatatattt tccctggcgg ttatgtccct
     7561 ggtgttactg aattagttga taatattaca aaaaacgatt tgcaactgat tgatttggaa
     7621 agcttacgtc gtgactacca attgacatta gaacattgga caaagaattt tcatcaagtc
     7681 caagatcaag tcacgaaaga aatgggtgat tccttctatc gaatgtggga tctatattta
     7741 caagcttgtg cagcttcatt tgaatcaagt aatatcgatg tgattcaata tttgcttgtt
     7801 caacctggaa acaatgacat cccaatgcat cgtgcataat tgaggcaaaa gtactgttta
     7861 aagactattt aaaaagaagc taagttttat gatgctccag aagtgaactt ttttgtctaa
     7921 cttctaggat tgtctctaaa gcttagtttc tttttcttta tattttcata ataaaagttt
     7981 ggttctttaa tttttaaaca tgacagaaaa ttttttcttc gttatacttg taatagaata
     8041 ctattttata acaaagggga tcgaatcaat gaaaaaaact gttatttata ctagtttatt
     8101 tgcagctttg tttttagctg cttgtcaatc aaataccaat caaggcacat ctgggaatac
     8161 gtcttccagt agcgaacagc gctcttcaca ggtatcggac tcctcaacaa aagcaagcac
     8221 atcttcgtct agccagacaa aaagttctag tgaagcaagt actcagtcag atatcaaagt
     8281 gtctgcagct cgtgcgatcg aattgttcca agataaatac ccagatactg caattactag
     8341 tttggaatta gatagtgatt ggggatctta cttctacaag atagaaggtg tcgatgatca
     8401 aaaagaatac gaagcaagaa ttgatgctca aaatgaaaaa atggagacag agaatccaga
     8461 aactctagat cgagatgaac aaaatggtca aaagaaaaaa gaagatggtc tggatgttga
     8521 taaattgatc acgattgagg aagcagcaaa aatcgccgtc gacaaagtag gaagcggtac
     8581 ggcaacagat tgggatttgg ataaagattt aggtactact tattgggaag tcaaagtaaa
     8641 agacggcaat caaagtacat cagtcaagat caatagccaa acaggcgaag tactgtcaac
     8701 tgaacaagat gattaagaat ttcttcggaa aacaagagtt gatttttctt ttagtcatga
     8761 tacactagac aaaataactt gtttgaagga gcgatttact tgagtttaga aacgaccttt
     8821 gccaatcata tctttgccaa tcctttgatg aatgcatctg gtgtccactg catgactacc
     8881 caggaattag atgaactggc tcattcagaa gcaggagcat ttatcactaa gagctgtacg
     8941 atcaatgaac gaaaaggaaa tcccgaacca cgctattttg atgttccttt agggagtatc
     9001 aattctatgg gacttccaaa cttaggtttt tcttattatc tagagtatgc tcttgcgtat
     9061 gaaaaagtgc aggaaaacca aaatcaaccg ttattttttt ccattgccgg gatgagtgtc
     9121 caggaaaact tggaaatgct tgagaaaata gaaaaaagtg ggtttaatgg gatcactgaa
     9181 ttaaatttat cttgtcccaa tgtgcctgga aaaccacaac tagcttacga ttttgaggcc
     9241 acttatgaaa cactgaaaga agtattcagc atcttttcta agccgctagg aatcaaattg
     9301 cctccttatt ttgattttgc tcattttgat cagatggctg atatcttgaa tcagtttcca
     9361 ttgacctatg tcaatgctat caacagtgtg ggcaatggtt tgtatatcga tacagaacaa
     9421 gaagcagtag tcatcaaacc aaaagaaggg gtcggcggca ttggcggaga gtatatcaag
     9481 ccgactgctt tggcgaatgt tcgcgctttt tatacacgtt tgaaaccaga aatccaaatc
     9541 attggtacag gtgggattcg gacaggacaa gatgcatttg aacatctgct atgtggcgca
     9601 agcatgttac agattggtac agagcttcat aaagaagggc cggaaatttt ttctagaatc
     9661 ataaaagaat taacgcagat tatgtcagaa aaaggatata cgtcaattga cgaatttaaa
     9721 ggcaaattac gcaccatttc atagcaaaga gacgaaggtc atgattgatc ttcgtctttt
     9781 tttataaaaa acactcgtct gttcattcct gtgcaagcgt actcattgta tgttagacga
     9841 acttgtggga aaataacaga ggcaaaaagg aggataatat gaatgatgca acagaattag
     9901 caaaagagct taaagaaaaa gaatttagtt ttcaagaact agttacggat atacagaaaa
     9961 aaataaagaa gcaaaatcat gaattgaatg cgtttgtcgc gcttgaacca ttcgagagta
    10021 attcccacga gctattgatt ccccagtcag aaaaagggcc attggctggt atcccatttc
    10081 ctttaaaaat gctcggtcaa gaaaaaaagg gatggctagc tacttcagga tctcgtttat
    10141 ttgaaacaca ccgagcttct catacatcta attatgtgcg gcaagcagaa gcgataggtc
    10201 tagttccttt tggacaaacc aatgcgccag agtttggttt caaaaatatt acagacccag
    10261 tcatctatgg cccagcaaga aacccttgga accttgaatg tacaccgggc ggatcaagtg
    10321 gaggagctgc tgctgcagtt tcatcaggaa tcgttccttt agctggtgct agtgatggcg
    10381 gtggttctat tagaataccc gcttcgtttt gcggattgat tgggctgaaa ccttcgcgag
    10441 ggacgatgcc agttggtcca tatgcttgga gaggatggca aggagctgct attgatttcg
    10501 gcttgacagt ttctatgaga gacacggagg ctttatttta tgggatgaga agtatccatt
    10561 ccggtgcgcc atatcaagta tcgccagttg agtggcaaac acatccaaga aaaaaacggt
    10621 tgaagatagc tttttgtgtt gattcaccga tccactcaca gattagtgaa gaggcagtac
    10681 ttgctgtaaa aaaagctgta gatttccttg gaaaagaagg gcatgatttg acagagattc
    10741 cttacccact agatggtcgt aaactgatca cgtcttatta tcagatgaat ggcgcagaaa
    10801 cagcagcaat gatccgctcg attgaaacag gcatccagcg agctgtcaga aaagaagaac
    10861 ttgaacccat ttcttggact ttgttccaat atggtcagaa gctctctgcc gctacttaca
    10921 tcgattctct gcatgtatgg gatgaagcag caattgtcat ggaaaaccta catcaagaat
    10981 acgatctatt cctttcacca acgactgcat ttaccgcccc taaaatcagc gaagatttgc
    11041 aaagtgatgc gataagagca cagatggaac acatcagtga ttgttctgaa gtagaaggtt
    11101 tagacgttgt ttcttccatg tttgaggaga gcttgaagat cacaccttat acacagttgg
    11161 ctaatctgac tggacaacca gcaatcagct tgcctactca tttgacaaaa gaaaacatgc
    11221 ctctaggaat ccaatttatg gctgccagag gaagagaaga tttgctattt caaatcggct
    11281 atctatttga agcaaatcat cagttccatt taccaaatcc atggaaatag cagaaacaag
    11341 gagaagaaga atgaagaaaa aaagattgtt tgctctaata actagtgcct tttttatttt
    11401 aagcgcttgc ggtacagctg ccgctaatca ggaagataac agctggagta atgtagaaaa
    11461 aaagaaagaa ttagtagtag cgacttctgg cacactgttt cccgcatctt attataatga
    11521 tcaaaatgaa ttagttggtt atgatgtaga tttggcaaaa gaggtggcta aacggttaaa
    11581 tgtcaaaatc tcctttaaag aatacaacgt ggatggacaa atcacttctg tttcaaaaag
    11641 agaatcagat tttgctgcga acgattttgg tatcacaaaa gaaagagaaa aaaaattctc
    11701 cctttcagag actttcaaat attcatttga cagtatgatc gtacgaaaaa aagatgattc
    11761 aggaatccac tcacttgaag atcttaaagg gaaaaaagca gctggcgaac ccaatactag
    11821 ctatatgcgt ttagcggaaa aacacggagc taaattagtc acatatgaca atgccacgaa
    11881 tgatcagtat ttaagcgatg tagcaaatgg tcgaacagat gttattctaa atgattatta
    11941 tctgcagaaa atggccgtat ctgctttacc agatatccct gtaaaaatac tggagaacgt
    12001 ttatttcaat gaaaacgaaa gtggtttttt attgaaagaa ggaaatgatg ctctgaaaaa
    12061 gaaaatcgat ggcgtattaa aagagatgaa agaagatggg acgacaaaga aaatatctga
    12121 aaaatatttt caaactgatg tttcagtcaa accgaaagaa acgatggctg agtcggtgag
    12181 tgagtgatgt actttcctct aattgatttt tccctcatgt ggacttcact tcctttcgta
    12241 ctgcaaggct tggtatacac attagggatt ggcttcgtgt cgtttctttt aggaaatctg
    12301 gtagggttgc ttttgacagt tttaggtctt ttggattggc tgcctctgaa tgtatttatt
    12361 cgtttttatt tatcgttctt tagaggcatt cccgcactag tcctgctgtt tctgttatat
    12421 tttgggttac cttatcaatt aagtgcctta acggcttcag tcatctgctt tacgattacc
    12481 agcagtgcat ttattggtga aatctatcga ggatcactag caggcgtttc ttcaggtcag
    12541 tgggacgctg gtttagcttc tggtttttct ttctttgggg tattgaaata tatcgttttg
    12601 ccgcaagctt ttcgaatctc agtaccggca ctcagtaacg tagctatgga tctagtgaaa
    12661 ggtacttcgt tagcagcaac aatcacagtg ccagaaatat ttcaaaaagc aaagatcata
    12721 ggcggtcgga cattcgatta tttttctctc tatattttag ttgcactgat ttattgggtc
    12781 atttgtatcg ggatcgaaaa agtgcaacag tatttagaaa aacgttctat gcatcagtca
    12841 atctgaaaaa tagaaatggt gctagcgtgg ctggcaccat ttctattttt tgtttcttgt
    12901 atattctgcc tagtatttta aaaccatttc atgtaaaatg taaatcgaaa atatgttcgg
    12961 aggtagaaaa catgaagacc ccgctaacca tcgaaataga atcctcgtta taccaatatt
    13021 gcatcgagca aggcggcttg gttgtagaag aagtcacgat gcctgatgac caaggaattg
    13081 tagatacgct tagctgcttg acaaaatttg atggaagccg agaatggcga tgctatgagc
    13141 tgaaagtgac aaaagcagat tttcgctcta cagccaaact gtcatttgtt ggacattata
    13201 attattttgt tttaccaagt aaactatatg aagaagtaaa aactgaaatc cctacaggaa
    13261 taggtgtttt agtgtatcgt ccgtacacgg ttgaagagga gatgcctgcc tctggtacat
    13321 ttctgattgc gaaaaaagca gcaaagaaag agcttgctgt accggaagaa gctttgacaa
    13381 accgcttcat ggcttcttta ttcagggaag taagaaaagc aaagcaaatg gagcgaggcg
    13441 taaaatattt tccaacagat caattgtaca aagaattgaa aagacgttca gaaaatcaag
    13501 atccattttc taacgaacga tattatgaac ggtttttaga ggaaatagct agtcaggcaa
    13561 tcaatgagtt gcaagaagaa gttatcgcgc ttcagcatga ttatgaatat ttgaggcaac
    13621 aacagcagat ccgtcggttg cctacagagc cattggagtg aaaaatatgt actatcctta
    13681 tttaagagga aaacaatttg acctattagc attaaaagaa gcactgtcgc gaggattgct
    13741 ctccaataaa atccaaccag tgatcgaacc agtacgtgat tccgctacgc ttaaaaatgt
    13801 gatcgaatta tttcaaaaaa agcaccatcg aatcgctgtg atccaaaatc cccaagtagg
    13861 acaattcaaa ttattcgatc agcatgtgca cagttggaca gtcaaagaaa atagctctgt
    13921 cgtccctgca cagatcttaa cgccagaaaa tctcagtgaa gtactggatt cacctccagc
    13981 gtttcttgtt ttcgatggac agcactaccc aaaagataca gaggtgtgga aacagttggc
    14041 aggagttgat tcgaaatttt tgataccaga tactagtcgc tttcgcatct ggctgcccga
    14101 aaacaaaatt gtgatccgtg actcttttca aacgagaaag catgttgaaa gttatgcaga
    14161 taaaacagat gactttttta gtgatgacta tctttttttc cacgcagacg gatatattgg
    14221 attttctgat ttcacgatcg aaggtagccg ttatttcgat aaagggttcc ctagccgagc
    14281 gcttgctatc catctaacgt atattgatgc ttacggcaat atacgcgtga aacattttgt
    14341 ctctgacagt aacgactctg ctaaagacca agcattgaag tttcttgaag caggagataa
    14401 aatgaaaaaa tggatcatgc gtcaccatca tcaactcttg attacttcag gaatgattga
    14461 attattggct ctttaccagc aacaaaaatt ccctggactg ggagtgttga aaaagtggtc
    14521 acttatgcat catttggaac ttattagtca cctgctagat catccaaaag attggcttaa
    14581 atattattca aaagttcagg aactatatga agtgatccaa tgattagata atgtaaatga
    14641 aaaaggaata gaaaagagga aactggatgt atattcggca aacaaggaaa gaagaagtag
    14701 aagaagtggt agaaatcatt aatgccgcag cggatttcat tgcttcgcaa ggctctcctc
    14761 aatggcaaaa cgggcagaaa ccaacaaaag aaacgatttt gaacgatatt gaaagaaaag
    14821 aaagctatgt attaatagtg gaagatcaaa ttgctggaac agctgcatta gtctcaagcg
    14881 tggatcccgt ttacacaaaa atagatggta gttggaaaga atcaactggt ccttatttat
    14941 cgattcatcg tgtcgcttta gcagaaagta ctcgaggaaa aaaactagca aaaccgttct
    15001 tagaacattt gttgacgatt gcagccagca aaaatatcca agatatccgt atcgatactt
    15061 atccagctaa tgaaccgatg gaaaagacca tctattctgc tggattcact tatcaaggga
    15121 tgattgaatt tccttttgaa cacggcgaaa gaaaagcata tcaaataatc atcaattgac
    15181 tataaaatca tctgagcaaa gataaagaca ttaacactac tgaaaaaaac aatcatatga
    15241 tagccaagag gttgtaacag aagtggccag cttcaaaaaa caagaaagaa tttccgaaaa
    15301 tgcttctcaa atttttgtgg aattttagcg tattttacga aatagctgct ttctgaaact
    15361 cccttcatcg agaggtcgtg acatagcttt tgtcacgacc tctcggctta tcctacgagt
    15421 attattcgat acatttatat caataatcct ttttttattt tatctgcagc ttcttggaac
    15481 gctccatcgt ttgacacgac taaaagtgag gggatagctt tcaaacgttt caactgtgct
    15541 aaatcttcta cataaaccgc cagtctggct gaaatctgtt cagatgaatc tccacgtttt
    15601 ttcaggcgcg attgcaatgt ttctttagag atcgtaataa agataggacg gactaccgtc
    15661 ccgaaatact catataaatg ccaaaaacca tttgctgtca aaacggcgta acaatttcct
    15721 actgtcagtt tctttttaat ttctgcttta ctggaaccat atttatgttg agcatattgg
    15781 tcccactctg caaactcatt tcccttgatc atctgattga atgtattgtc agaaacaaaa
    15841 taataatcct cttgatcttt ttccccaggt cttggtgatc gattcgtgta agtaatgatc
    15901 ttttgttccg gctgaaaaat agcttctgcg agtgaagttt ttccagaacc agaaggaccg
    15961 ataaatacat agcaataatt cattgtcatt tctcctttga tgattgaaca agtgaaaaag
    16021 ctttggaaaa tatttccaaa gcttttaaaa gtaactttgc ttttttgtat attataccag
    16081 caagccagtc acaatagcac ttaaaaagct gactaaagtc gctgttagca aaattttcaa
    16141 tccgtgtttt gcgacaagat ttcctttttc ttcatttaat cccttcatcg caccagaaat
    16201 gatcccgata gaagagaagt tggcaaatga aacgaggaag acagatataa ttgctgttgt
    16261 acgctcagta aaatggaaat taccatttgc taattctgtc atagcaacaa attcatttgt
    16321 aaccagttta gtcgccatga tactaccggc atccactgct tctttccatg ggattccgct
    16381 gatgaaggca agaggggcaa agatgtaacc taggatctct tggaaagtga tgccgaatat
    16441 cccgtggaag atagcattga tcatggcaat caaagcaaca aaaccgataa gcatagcagc
    16501 aaccgtgatc gccacatgga aaccatcaag aatgtattct cccaacattt ggaaaaatgt
    16561 ctgttctttg ttttcttcaa tgatcagctc atcttctttt tcttctaata catagggatt
    16621 tacaattgaa gccagaatat aaccgccaaa taagttcaaa acaagggcag tgatcacata
    16681 tttagaatcg atcagtgcca tataagatcc gacgatcgac atagaaactg tagacatagc
    16741 cgatacactc atggtgaaca aacgtttctc agataggaag ggtaattcct tttttatgga
    16801 aataaaaact tccgattgtc ctaaaatagc agaagctact ccattataag attccaattt
    16861 gcccatcccg ttgattttac ttaatcctag accaacagct ttcataaata atggaagaat
    16921 cttgatatag cgtagaatac cgataatagc agaaataaat acaattggca tcaatacgga
    16981 aagaaagaaa ggtgcacttc ctttatttgc tacaccggca aaaacaaagt caacaccttg
    17041 cccagcaaaa gcaagaagat gatcaaacat ttttgccaat acagaaacaa ccgctgtacc
    17101 aaaagttgta cgtaataata cgaaaccaag aacaagctgt aaaacgaaca tcacaattag
    17161 tggtttcaat ttgattgctt ttttgttact gctgatcaaa aaagcaagcc ctaatgtgac
    17221 aaataaacca ataataccta ataaataact caaataatca ctcctattcc aaattccgtt
    17281 ttattttacc tgttttgcaa ataaaatact aatctttagt gaaattttca ttactttttt
    17341 agagtgaaac gcattcattt tccattagaa aataaagcga acaaaataaa aggtttaaaa
    17401 agtgtaacgt cttagtaaag tctataaaaa aacgaaacta tcgattaagc taatagtttc
    17461 gttttcaaca tttataagta aactttttct attggtaata tagattttcg gaagggtaga
    17521 caggtgcgca ggtaatatcg attcctagtt ttttcaatgt ttgttcatca tttttattga
    17581 ccatcacagt agagtgggct tgtgctccct caagttcagc tagtttatca taagcaactt
    17641 gagcgattgg attcgttact gcactgattg ataaagcgat caagacttca ttgatgctta
    17701 gtgcatccaa agaggaatga agtgtctttg atttcaatcc ttgtattgtt tcaagaacta
    17761 atggtgacaa taaaggaatg tcatctgcga tatgggctaa atgttttact gcatttaaga
    17821 taactgccgc tgacgcatcc atcaatgaac ttgtacgccc ggtaatgatg acttcatctg
    17881 gtaattcgat tgcaatcaca gcagaaggat cttttgtagg actttgcgct tgaatcttat
    17941 ctgcatagtc atgggcaggg actaccacgt ttcggtcttc aggacgtaaa ccgacttctt
    18001 ccataatcag tttgattcga ttaactgctt cttcgtcgat caatcctttt ttgaagtcgc
    18061 attctgtttg gaaataacga cggatgattt cttgtttaga ggcttcttgg acaacggtat
    18121 catccacgat cccaaatcct acacgattca cacccatgtc agtaggagat tgataaacag
    18181 attctttacc agtaattttt tcaataatac gtttgattac aggaaatgtc tcaacatccc
    18241 gattatagtt cacagctact ttattgtagg catcaaagtg gaaggaatcg atcatattga
    18301 catcttttag atcgactgtg gctgcttcat aagcaatgtt cagcggatgt ttcaacggaa
    18361 cattccatac tgggaaagtt tcgaacttgg agtaaccagc tgcatgtcct ttttggcttt
    18421 catgatacag ttggttcaag gaagtagcga gctttccact tcctgggcca ggagctgtca
    18481 ctacaacgat tggtttagtt gtttcaatat actcattttt tccaaaacca tcttctgaga
    18541 cgattttttc tacgttgact ggatagtctt cgatttctga gtgtttatag accttgatgt
    18601 ttcgtctttc tagtttattg ataaagactt tcgtggcagg ctgtccacta tagcgagtga
    18661 taacgacact gttgattaat aagccataac cacgtaattc atcgattaac cgcaagatat
    18721 ccatatcata agtaatccca taatcaccac ggatcttatt acgttcaata tctccagcat
    18781 agacgcaaat cagtatttca gcttgatctt tcaatttttg cagcaatttg attttcgcat
    18841 cttcttcaaa tcctggaagt acacgtttcg catgcttgtc gtcaactagc ttcccaccaa
    18901 attctaaata taatttgtca tagtggttca ctcgttccaa aatatacgct gactgctctt
    18961 caatatattt ttctgaatca aaaccaattt ttttcactag gttccctcct taagtactaa
    19021 agcatttttt catttttttg aggattcgtc aactggaaga gcgaaattcc tcaaaaaaac
    19081 aaagaaaatg gtttaaacca acttgtctag atagttattc attggtatga tagtttttga
    19141 taaggaaggt gctacatgaa aaaaagacag aaaaagaaaa acgcatataa acactatatc
    19201 cgttcgattt ttaccggtta tgaaagaatg cttgaagatc ccgaattgga acaattgacg
    19261 tttacttatc taaacgaaga aacgcagcta actcgtgatg agcatcagcg cattcatttc
    19321 acaacaagag atctgcctag taaataaaaa ataagataaa ggtcatcgga ttcgattctg
    19381 tcctatcaga tggaaagact agttgatcga aaaaaaggct gtaccaaatt ttggtgcagc
    19441 ctgttttatg gagcattgcc cgctcttttt tataacaatt ttttacagaa aatggtacta
    19501 ttgaagtatt aataagtgaa aaacagatga gtaagaggag gcaagtagta tgaaagagcc
    19561 agatacaaat gcaaattatg agccagacga actagaggag acgaatgcgg atcaggatac
    19621 aggacaagaa tcgtcttctt tttacgatat caaagaaaaa gcaagcatga atctttccca
    19681 attattagaa gacttacagg cttttgaaaa agctgtccgc gaagaagata tccctgagat
    19741 ctaccgttta tacaatggcc gattgaatga agaattaaaa agaagctcaa atgaaaatca
    19801 cgagatcgat caattgctga tgcgtaagat ccatgatcgt tttttacagg aatttccttt
    19861 tatggaacaa gtagaaaaca tctcgccaac gatgagctat tacaaaatcg gcacttatta
    19921 ccatgatcgg cccacggtcg gtattgatgc aagtctgcca gaaatttttg ttttgcctaa
    19981 gatcgatgaa gagtgggaga aatattccca accggagtca acggactatg acaaaaaaat
    20041 caatgagcta gacgcaaagg tgatcactgc tcagacagaa attgaacgtt tagatgaaca
    20101 aataaaagaa atcaatcgac aaatgactga tttgaacgac aataaaggat tcttgaatcg
    20161 taaaaaaatc gaggaagaaa ttcaagaatt agagaagaag aagcaagtac tatctaatga
    20221 aaaattaggc tggcttcctt atattgagac gcctgaaaca atccagcagc aaaaagaagc
    20281 attgaagcaa gaagcaagag cagaccagct tcgtgcagcc atcgtagaaa aagaacaaag
    20341 gcaaatcaga cgctatttcg gtagcaaaga gggattcggt caagcaatcc atgaattctt
    20401 gatgaattat cttggcaatg agaatcctaa taatcaatct aatgaaggag gttccgagta
    20461 tgaatgaaca cgatgaagca gaatggacaa aaaatgaaga acaaacagaa gatcatgaag
    20521 aaacgaacac ttcattggaa gaacaaacaa gtaatcctct ggatgacaca gaagaaatcc
    20581 ctatgctaga ggaaacaaaa atacacgaaa aagaaaaagt aactccgacg aatacgaata
    20641 ctgcagaaaa cacccatgct tacgaaataa ctgaaaatcc cgggtattta gaaggaaaag
    20701 agcaagatca tcaagatatc gtcagtttga ttgaaacagc ggaagcagaa ttagcggatt
    20761 tacgtatgag aaaagatttg atcgaatcag attttccaca attattagaa tcatatgatc
    20821 gttttatatt gaatgaagaa ccaatctcca cgatcggaaa gacaagcctg atcgaatact
    20881 tcacgtatga attactgaaa ccgttgaatg atattggtct ggaacggtca aattcagctt
    20941 atgacacatg gaaaacaaga catttttcga tcaattatac gttgaatgga caaaacgaat
    21001 tagtcttttc ctttgtatta ccgaccatcg atcaacgata ccaagtggaa tcgatgagtc
    21061 tcctaaacgt atcaccagag acaatggaaa tcaatgtcca agatgaccgg gtgctttctt
    21121 tgatccgaca ctggtcagtg gatcgagtat tctctgcagg gcagatcacg atattcaatc
    21181 acaaattgaa tcaattatta gcccatgcaa gaacacttgg ttttaccgtt aatcagacat
    21241 tactagacaa tacgaagcca cttcgtttga atcttcagag cgaatttgaa ttgacgaatg
    21301 aagtattgga tgatattttt atcgtggcaa tgaaaaatcc atcctacgat atggaaaaga
    21361 tcaacgaaac tacttatcaa gtacgattag ataaaggaca gtctttaacg ataacaacaa
    21421 acgaaaaaga tcaaacagtc ttgtcgatct catctggaga ctacccacga tctgtcattg
    21481 atttctttat caattacgaa ttcttggtcc cattaatggt gagaaagtcc tgattggata
    21541 agttggatta ccagatgtca ttcagataat tctgttccaa aggacttgcg gcagttatcc
    21601 agaataattg tcacaagtct tttctgtatg tactaaatgg acgtgaataa cttgctgatg
    21661 aaggagggat ttcattagga atgtccacaa ataaaatagc acagcttagc ttattgtctg
    21721 ctgcttgtgt agcaggtagg atcgcttttc aatttattcc gaatttccag ccaatgactg
    21781 ctattttttt atttatagta ctttacttaa gcttaaaaga tgcgttaatt gtcatgagtc
    21841 tttctattgc gatcagcagt ttttattttg gtgttggacc atgggtcatc ggccaatgga
    21901 tcagctatac tgttgttctg agtttgtttt caatcgtctg cttgagaaaa acagtgcaaa
    21961 ggaatctatg gttaaaggga gtctgttttt ttctggcggg catggtttac ggaataggta
    22021 tgaccgtttt tgatacgctg ttatatcgtt tgcctcaacc ttggatctat taccttcaag
    22081 gggtgtcgtt tgatttgatg cacagtatag gcaatgttgt gttctttctt gtttttctgc
    22141 cagtcgtcaa acgtttttac aatcattcag gaggaaaaaa tgaaaaaaat aatttatagt
    22201 ttgcttgcaa tgagtgtcag tatactcatt ttgacaagtt gcagtacaac ctatacacaa
    22261 tcggcttcca accaaaagga ggaagtaaaa acatcgcaaa aagcaacaat cacgttacaa
    22321 gaaaatggtc aaaacttttc ggaaaaagaa gtgttcttca aaaaaggcga tgatttactg
    22381 agtattttga aacgaaattt tgaagtcaaa gaagataacg gcttcatcac ttcgcttgaa
    22441 gggcactcac aggatgagaa aaatcaactc tattggatgt ttactgtgga cgggaaaagt
    22501 gctactactg gtgccaaaga gatcaaattg aatgatggac aatcggtcat tttcaatttg
    22561 tctaaactat aagtttcata aaaaactgtt aaagggcgaa tattgccata attcagtgag
    22621 ttcagttgat gaaagaagga aaataacatg gaaaatttta aaaaaagcgg aatgttttcc
    22681 gtaattgctg ctctaggggc taatattcta gttgctatca gcaaatttgt cggctatgca
    22741 atcagtggca gtgccgccat gctaaacgaa agcatccaca gtatcgttga ttgcagcaat
    22801 cagattttgc tgttattcgg tgataaacaa gccaataaag gacagagcga gttgcatcaa
    22861 tttggtgaag gacgagcaaa atactttttc agtacaatcg tcgcaatgat gcttttcttc
    22921 ggcggtgggg cacttggggt gatggaagct tttgaaaagt tgacgcatcc atcccatgaa
    22981 gtgggtaatc cgatcattgt tatagcaata ctgttatttg gtttggtaat cgaaggaagt
    23041 tcgttacgcg tggcaatgaa agaaatcaaa gaattgaata ctgaaaaact ttccacgatg
    23101 cgctttttgc gcgaaagtcg acacagtgaa atactgatta tttttacgga agacttgtgt
    23161 gctgtaatcg gtttggtctt ggctttagca ggaacaatat tgacttatgc aaccgggatt
    23221 gctgcatttg atgcgatcag cggattgctg atcggtttct tgctgatggg agccgccatt
    23281 ttcctagcaa aagaatttta tagtctgatc atcggtgaaa gcgtgacagc aagcgattta
    23341 tcaaaaatca agttagcttt tgaacgtcct gagatcagtc ggctgatcga tataaaaaca
    23401 gttcatttaa gtccaacgga gattttagtt gcagcaaaag cagatatcgt tggtaacaaa
    23461 gagaatgaag cttactcggt catcaatgat attgaaaaaa atatgcgtca gtctcttcct
    23521 gacaagaaga tgtatatata cattgaaaca gataaatatg acccaaatta ttctcgtaaa
    23581 taaaacgttt attcatgaat tgaagcaaaa atgagaaaaa tataatcttg tttttaaata
    23641 aaacggctac aatttagcga atttatgtta caatgagtcc gctgtttatt tgttgtaatt
    23701 aaaggagata ttttaatgaa caaaaagaaa agtgcgccat ggcttcaagc tttgcatgca
    23761 gtgatgccac tttatataag ctatatacca gtaggattag cttgcggagt attgttgcaa
    23821 aaagttggat ttgatcctct cttatcagga ctgttatcga ttctggtctt ttccggtggc
    23881 gcgcagtttt tagttgcatc tatgcttacg acgcaagcat catttgcaac gacattattg
    23941 atggttttct ttttagaatt acgctataca ttattaggag caagtcttgc cggttttatg
    24001 aaaaaagaaa agcggacgtt tttggctgtc ttttctcaat cactgaatga tgaaaactat
    24061 gcggtgaact acttaaagtt ttcaactgac ccttcctgga ataaaagaaa ggctttatat
    24121 gtcaattggt tctcaatgac tgcatgggcc ggtagcaata tgatcggtaa ttttttcggc
    24181 tcggtgattc gagtagatgc tgaccttgtc cattttgctt tgacggccat gttcattttc
    24241 atgtttatca tgcagatgaa aagcgcacta ctgatcttta caggtttatt ctcaggcgta
    24301 ttaggggtcg tattcatggt attattccaa aatactttcg gattgattgc agcaacagtc
    24361 attgcttcat ttgccggatt tatgctggag aaggcattca aaaaagaaaa agctaagaaa
    24421 ctaagagacc gcggtaaaga tgtcaatgag ccgctcttca acttcccgga acaggaggcc
    24481 aatcaccatg actaaactat atttgctact tttagttgct tgtctgttca tcgtggcata
    24541 tatcccgcgc ttgttcccga tgctttattt tactcatcga aaagtgccat cctggttcag
    24601 tgactggatg aaatatgtac cggtggcatt atttgcggcg ttagctttta aagatgtttt
    24661 cattactcat gaacatctgg atattgcttg gaatatcaaa atagctgcaa tgattctagt
    24721 agcaggcgtg gcttacaaaa cacgttcgat ggcgttgtca gttttgacag gacttgcgtc
    24781 tgtctttttg ctgtctatgc tttaaactgt tttattttat taaaaacaga gattgcgaca
    24841 taagttgttc aaactgatct atccgaactg catttgcaac agtcaattct ggatgcaagt
    24901 ttattcgtag ggataaaaaa gattagtgtt ggcttatgat gcaagctctt ttttatttta
    24961 ggaattagag agggatttgt ccttctatga ttttttgcta taatagggaa gatgtttatt
    25021 ttatgaaaga atagttgagg gaatttaaat gaataaaaaa ttgatgcaag gaacattttg
    25081 gctaaccttt gctaatcttc tatgtaaagt tttaggggta gtctatttga ttccctggct
    25141 aagtatgatg gggaacaatc aagatggtat gcttgctacg acattgtata atgttggcta
    25201 tcttccttat ggattgttcc tgatgcttgg tacagtcgga tttccaaatg cgattgcaaa
    25261 aaaagtagct gtagccacaa aagaaggaga taacgctgct tgtcggctga tttttagaag
    25321 tacgatcaat atcatgtttg tcatcggtat cgcctctgct gcactgatgt atttatttgc
    25381 tcctttacta gccggaatca gtccgattgc taacgttaat aatgggatac tagctatcag
    25441 aagtttatgc ccatctttga ttgctatccc aattcttagt gcaatgagag gatatttcca
    25501 aggaaaaaat gatctgcggc cttatggaac ttctttgatt atcgaacagg ctgtgcgagt
    25561 gatcgttatc ttggctggta cttattactt gcgcgtattg actgacggaa ccatattaga
    25621 agctgtattg atcagtacag tcgcttcttt cttcggtggg ttagctgcga ttatccatat
    25681 gtatatcgtc ggacgcagaa aagacttctt cgaacttaaa gattttttga tttccagccg
    25741 ttatttcgaa agagaaaacc gatctgcctc tgtctctatc attcgggaaa cactaccgtt
    25801 tatttttgtc ggctcagtca ttactatcgt tcaaatgatc gaccaagtaa cgatgaaacc
    25861 actgcttcac tttttccgtc cagagatcgc agatcagcaa ctggaattct tattcagccg
    25921 tgcttctgtc aatccaaata aattgacatt gatcctgatc tccatggtag gaacagtagc
    25981 tataagcagc ttgccaatat taagcacgat gaagaaaaaa gatcggatac aaatcgaaaa
    26041 aacagtagga gatagttttt cgattgcgtt attgattctt cttccttcat tgactggaat
    26101 gtctttatta gctggaccac tatacacatt gttttttggc tatgatcctg aaagtgtcgg
    26161 atatttccaa atggctttgc tagcttcttt gtttttctct ttattcacga tcctatctac
    26221 gatgcttcaa tctttgaatc accatcgttt tgcgatccga ttaactgtag aagcaattat
    26281 cctgaaagtc atcttccaag taatcggatt aggattagtt ggcggatacg ggatgagctt
    26341 atcaaatggc ttagcattcg gtattgtctt tgttcgcggc tatcacttta tgtgcaaaga
    26401 ataccgaata gcacctttag caaagatcag caattttttc ttaaaaactt tccgctccac
    26461 cctgattatg cttgcagtat gttttgccgt tttctttttg ctgaatcagc gattgtcaat
    26521 ggaatcaaaa agctatgcaa tgatttattg tgtggctgta ggaagtattg gcggcttagt
    26581 atttttattt tctcaattcg gaaaaaatgg gtttcgaatg ttgaaaaatg ttaaacatca
    26641 tagcagaagc aaagaatagg ttaactaatc gttttttgct gtcacttgaa aaacggcaac
    26701 tcgtatgatt acgcttgtcg tttttctatt ttccaatttt agtttcatat ctaatcttac
    26761 ttatgatata gttataaggt ctggaaaaat tctttgaaac gaggaaatta aacacatgaa
    26821 acttgcagta gttacagata gttcggcata tctgccggaa cgtatcaaga accatcccga
    26881 cttattcgtt attccaatcc ctttgattat ggatgggaaa atttataacg aaggaatcga
    26941 tatcgaagcg gatgaatatt atggactttt aaaaaacagt aaagattttc ctactacttc
    27001 acaacctgtc gtaggggaag ttttgggttt atatgaggaa ttgaaagaga aagggtatga
    27061 cacgatttta agtatccatc tttcttcagg gatttctggc tttgtcaaca cattatttgc
    27121 gatgaaagat gacatcagcg gagtaacggt cattccttat gactctaaga tcactagtat
    27181 gccgatggga cacatggtag aagctgcctt agacttaaat gatgaaggtc agtcccttga
    27241 tgaaatactt gcacatatcg atcgaatccg agataatacc tacgcttatc tgattgtaga
    27301 tgatttgaac aatttagtac gaggaggacg tttgacaaat ggtgcagcgc tgattggcag
    27361 cttattaaaa atcaaaccga tcctgacatt ttctgaaggg aaaattgttt tattcgaaaa
    27421 aatccgttca agtaaaaaag catttgctcg agctgaagaa attattggta gaagaaataa
    27481 cgaaatacaa ccgccagtca aactttacgt gatacatgca aataatttag aagtagcgat
    27541 tgcggagaaa gagaaattgc agaaaaaata tccaaatgca gaaatcgaaa ttggtcattt
    27601 cggaccagtc attggtacac atttaggtga aaaagccatc ggcattgcca tttcagcgca
    27661 ataattcctt ttattcaaaa aacataccaa aaatattcca acatcatctt ggactttcta
    27721 catgttacta atgagcgtgt aaaagaacga gatggtgttt ttatttctat caatgaagct
    27781 ctttttcttt gcaatcctca cttcaatcct ctataatgtc gcatatagtt tagtaaatga
    27841 gtaaactact aatttactta tttactaaaa ataaaaggat gaggagttaa aataatggaa
    27901 ataccaacaa atttaaaaca taaaccagta atcgttgtag aagactatga taaagttgat
    27961 ggaagaaatg cattaaatac ggatgcaaaa gggctttcac tgggccttgc tcagtggaat
    28021 gatcgtggaa aagtcgatat ctcaggcaag gtatggcgac atactggaga aaaatggtca
    28081 cgacagtcgg aagaattacc aatcacacgt attttagatt tagcgatctt agctgcacaa
    28141 ggaagtttat acttccaaga tgcttatcgt tatgaaaaat tttatgatcc agaaaatcca
    28201 gtcgtagaca tcattggatt acaagggaac cgaatgacgg tagaagtaga taccaaaaat
    28261 ccaaagatcg atgaagacat cattttgtat tacgatacac tacaaaaaga cggagaactg
    28321 attggggaac gattccgtat tttaaaacgt cttttagatg agctaggata ttaatagaca
    28381 gagatgatca aaaggggaag agaagcatgg agaatttctc actaacagaa aaccgaacct
    28441 tttcacggct agaaaagcaa atgatctgga agaaaccgaa aagccatcgg acaagtgcag
    28501 aagaatggcg gatcgcctcc gaaatcaaag ggaattggca agatcctgaa atgaaaatca
    28561 gtaacgtact tttggaagga gatgccgggt cggggaagac acaattagcc aaagcactat
    28621 ctgctgatct gcaacttccc tatacaaaag tgacctgttt tgcagatatg gacaaatcag
    28681 atgttttcgg agccttatta cctgtagtag attctaataa ggaacaagac caagaattac
    28741 tagaagctat ttaccaaaca gatacacttg aagctgtact gacactgatc cagaaccatt
    28801 acggcattga tcctttttct gctaaagaaa aattagcaga gctagttcaa aggatcgaag
    28861 ctgattatcc agatgcaatc cattacagct attacccttc tgaaatcgtt cgagcgattg
    28921 aaaaaggata tttattagag attcaagagc cgactgtcat ccgagatgcc tctgttcttg
    28981 tggcacttaa ctcagcgctc gaaccaaatg ggatgttgaa tttaccgaca ggaatcattc
    29041 gtcgccatcc agattgcgtc attgtgatca ctacaaatcg aaattaccaa ggaaatcgcc
    29101 cattaaatga atctttaaga gatcggatgc aacatgcgga aaaaatggat cttcctgcct
    29161 tagaagtcat ggcagaacgt gcgatggcga aaactatgat ccaaaaacaa gaacttctct
    29221 taaagatggc agagattatc cgtttgttgg atgaaactgc aaaagctaac gccatcaaag
    29281 gtgtagcagg aatgcgttct tatttttatt gggcaaatac ctataagcaa ggacaagatt
    29341 tactccagtc gatttatcca aaagttttgt ataaattatc cactgattca gatgaattgg
    29401 caattcttga acaagctttg tctgacagtg gattgctact ggaacttcag gacatattga
    29461 gaaaagaaaa atggggtcat cctcaatctg agcatacaaa aggaagaacc attagcgccg
    29521 aagaagcaaa tgaacgaaac atcactgaaa atgctgaaga aattctgcgc ttagatgaaa
    29581 agaaatcgtt gtctgctgaa gaaccaaatg agggagaaga gaaacaagaa gaaacaatag
    29641 aaaaaaacga gattcctcct caaatgcaaa aagaacgcag tagcgatatc gaaggaaaaa
    29701 atcaaaaaga acaacaaaca ggagatgatt ctcaagaaat gtctgcttct gacatggaag
    29761 cacatgataa ggaaatcaag aagcaactga ataaagaagc gcgacaaatc atgaaggaaa
    29821 cgattcatga aaaagaaggt ctcatcgttc accgaccagc tttccaagga aaaacgccgg
    29881 aagcacgtga gctacacatg caagtaatgc caatagtaga atcacttagc cggcaaattt
    29941 tagagttact ggataatgaa caaacagaga cgtaccaaaa aggaaaatac gaaggtcagc
    30001 ggttcaatgc aagcaaagta gcatatggtg atttgagaaa ttttgacaaa aagaacccgc
    30061 cacatgagca accttcttta gcggtagctg tacggatcga tgaatctggg tcaatgatac
    30121 gggatgatcg gatcgaagcg gcaaaaaaag cagcgattgc cattgccgaa ttttctaaga
    30181 aagtcgatat cccattgttg atttacggag atacagcaga ccgttcgtca agagaaaaga
    30241 cttctttgtt ttcttataaa gaatttgaag acggatttca atggttaaat gaaaaattag
    30301 tcactatgaa accaaggcaa aacaatcgtg atggtgctgc acttcgttta gcagcagaaa
    30361 aattaaacag acaatccgca acaaccaaac tgttgcttaa tattagtgac ggtcagccaa
    30421 aagcgttgcc ggattataca ggcaaaaaag caaaagaaga tatccagtct gttttgaaag
    30481 aatatgaacg tcaaggaatc ctatttgtct ccgcagctat tggccaagac aaagaagaaa
    30541 tcaagtcgat ctacggtgaa agtcgttttg tagatattac tgacttgaat gaatttccca
    30601 agcaaatgat tcaactgatt gcccgctatc tatgataaaa
//
LOCUS       DAZKCH010000029        30460 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000029 DAZKCH010000000
VERSION     DAZKCH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.029"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(451..1761)
                     /locus_tag="ACG84X_001312"
     CDS             complement(451..1761)
                     /locus_tag="ACG84X_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFP9127199.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3131)
                     /locus_tag="ACG84X_001313"
     CDS             complement(1773..3131)
                     /locus_tag="ACG84X_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9127200.1"
                     /translation="MSDKIGYMFGDLGNCFILGLVNSFLMIYYTNVLGVSGAIVGTLF
                     LISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKYPFCLVTVILFLPFVQHLPMT
                     VKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDRTSLSTFRSIGSAIGGSTTGF
                     FIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYMLTCKLTTERVRVVKNEKVSA
                     SQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLFNDYFHNKQAMSVALLFTYGT
                     VVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFLHITNAWVYLILLFIATLGSG
                     LFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARKVGQACAGAVGGFMLALIGYQ
                     SSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLVGYPLNRSKTVFIGEELKKIN
                     ER"
     gene            complement(3333..4901)
                     /locus_tag="ACG84X_001314"
     CDS             complement(3333..4901)
                     /locus_tag="ACG84X_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFP9127201.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4905..5315)
                     /locus_tag="ACG84X_001315"
     CDS             complement(4905..5315)
                     /locus_tag="ACG84X_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFP9127202.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5312..6235)
                     /locus_tag="ACG84X_001316"
     CDS             complement(5312..6235)
                     /locus_tag="ACG84X_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFP9127203.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6232..7110)
                     /locus_tag="ACG84X_001317"
     CDS             complement(6232..7110)
                     /locus_tag="ACG84X_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFP9127204.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7097..8434)
                     /locus_tag="ACG84X_001318"
     CDS             complement(7097..8434)
                     /locus_tag="ACG84X_001318"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFP9127205.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8437..9540)
                     /locus_tag="ACG84X_001319"
     CDS             complement(8437..9540)
                     /locus_tag="ACG84X_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFP9127206.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9614..11122)
                     /locus_tag="ACG84X_001320"
     CDS             complement(9614..11122)
                     /locus_tag="ACG84X_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFP9127207.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11088..11780)
                     /locus_tag="ACG84X_001321"
     CDS             complement(11088..11780)
                     /locus_tag="ACG84X_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFP9127208.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11802..12776)
                     /locus_tag="ACG84X_001322"
     CDS             complement(11802..12776)
                     /locus_tag="ACG84X_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127209.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13076..13948
                     /locus_tag="ACG84X_001323"
     CDS             13076..13948
                     /locus_tag="ACG84X_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127210.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14406..16604)
                     /locus_tag="ACG84X_001324"
     CDS             complement(14406..16604)
                     /locus_tag="ACG84X_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127211.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16836..17828
                     /locus_tag="ACG84X_001325"
     CDS             16836..17828
                     /locus_tag="ACG84X_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9127212.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17888..19309
                     /locus_tag="ACG84X_001326"
     CDS             17888..19309
                     /locus_tag="ACG84X_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFP9127213.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19302..20801
                     /locus_tag="ACG84X_001327"
     CDS             19302..20801
                     /locus_tag="ACG84X_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFP9127214.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20840..22234
                     /gene="uxaC"
                     /locus_tag="ACG84X_001328"
     CDS             20840..22234
                     /gene="uxaC"
                     /locus_tag="ACG84X_001328"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFP9127215.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22393..23076
                     /locus_tag="ACG84X_001329"
     CDS             22393..23076
                     /locus_tag="ACG84X_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFP9127216.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23078..23914
                     /locus_tag="ACG84X_001330"
     CDS             23078..23914
                     /locus_tag="ACG84X_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFP9127217.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23925..25679
                     /locus_tag="ACG84X_001331"
     CDS             23925..25679
                     /locus_tag="ACG84X_001331"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127218.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25955..26296)
                     /locus_tag="ACG84X_001332"
     CDS             complement(25955..26296)
                     /locus_tag="ACG84X_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFP9127219.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26364..28535)
                     /locus_tag="ACG84X_001333"
     CDS             complement(26364..28535)
                     /locus_tag="ACG84X_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFP9127220.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28746..29603
                     /locus_tag="ACG84X_001334"
     CDS             28746..29603
                     /locus_tag="ACG84X_001334"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFP9127221.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29674..>30460)
                     /locus_tag="ACG84X_001335"
     CDS             complement(29674..>30460)
                     /locus_tag="ACG84X_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9127222.1"
                     /translation="KLSIPTTTPEETLDQVFEFFDRYELKGIGIGSFGPIGIDKTKDN
                     YGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTDVNAAAYGELKQGAAQGKNSCIYLT
                     VGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPDDHYEGTCPYHKDCLEGLAAGPSIE
                     ARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLTLAPEKIILGGGVMNQDHLLQKIRQ
                     QFVELMGGYMETPQVSEYIVRWGLPNESGIIGSLLLAEHEHQK"
BASE COUNT         9099 a         6274 c         5391 g         9696 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct tgtttttata ttcacaatgt tggcttttta
     3181 ttgcattatc ttgacagata aaaaacaaaa aataatctaa aaacattgat gcataagatt
     3241 gataactttt tttacataac aatatataca aacaaaaaaa ttcactaact agtgaaaata
     3301 agttagtgaa cctcatttat taaagaatta aattacagat gatcttttcc atcatacttg
     3361 aaaaactcaa aatcagcata acttcctctt tttttattta gatcatgcac tgctatcccg
     3421 ataaaatttc cagtaaaccc tcctgagagt atacacatgt ttttttgcgg acctactttc
     3481 ttccattctt cagttgatac gtctttcaaa tgaaactgtg ctgtctcttt ctttacagtg
     3541 actttcaaaa aagtcttctt ttctgtgagt ggaatcgtcc aatcttctat ttgtgctact
     3601 ccgttttctg attctatcat acgtaggcat tttcccttgt cctcattcca agtaacataa
     3661 caataaatat aattggattc atttaagtac agtaccagtc cagccatctg attaaaatta
     3721 ttaggcatgt attcaaatgc tgtctccgca tcaaaagtaa aatccgtttg ccgaatagct
     3781 aacaaatgat gttcgaaggt agattgaaga gattcaccgg aaatcagacg taaaaaacct
     3841 ggtctacatt ttgtatcaca ccaatcagca tttggcaaaa tgcgtctggc attccagttc
     3901 ttctttagct ctccttcaaa tgtatccata aactgatgat ctttttcttg ttgtacctct
     3961 tcatttgtct caatcattat ttcttccatc ggagttgtct ggctatcttt aagtcttaac
     4021 caatcgtcgg acgtccaata cacttcttga atagcggttt ctcttcccaa aatagccgca
     4081 ccgtttaatg gtctggtaca aagatatgtc atgtaccatc ttcctgacgg ggtttgtact
     4141 aagctcccat gtcctgtaca ttgcaatgta gaagcaggtt tgtcactagc tgtcagcata
     4201 ggaaaaccag gatcaagctc gtaaggacca gtaatattct ttgctcggca aactgtaact
     4261 gaatgtcctc ttcctgtacc gccttctgcc gtcatcaaat aataataccc gttacgaaaa
     4321 tacaaatgtg gtgcctccgt tttcgctaat tctgtacctg caaatatttt atagatggga
     4381 ccatcaagct tcttcttctc tgcatcatat tcttgtaata cgataccgct ggatttattc
     4441 ggtgtgtcca gacgataatc ccatagttca ttgacaagcc atttttttcc cgtttcaaga
     4501 tcatggaaca aagaaggatc aaagccgtta ctatttaaat aaattggttc ggaccaagga
     4561 cctgtgatct cagatgcagt gatcaaataa ttgtggacat ctttaaacgg acggcctgca
     4621 cttttgacat ctgtgtaaac aagataaaac aatccatcag cataactgat ctgtggcgcc
     4681 catatacttc catttgtagg atttccttgc aaagatactt gagtggtcaa aatatccgtt
     4741 gtatgtgacc agttgactaa atttttcgac tcatatactc ggattcctgg aagccattca
     4801 aaagaggaga caataatgta ataccgctct ttcactctta atatattagg atctggattg
     4861 aatcctctta aaataggatt tttcactttg atagtctgca tgattcaggc tccttttctc
     4921 attcttactc gatataaact gaatgcccca gctgcgaaat aaaaaaatgc aaaaggaaac
     4981 gcaataaact gagtgccaat caacaatatg aatcctgtta taaaatacaa accagtggca
     5041 gttgttaagt attttccttt agcagtcaaa aacaatgcta ctgctaaaaa agcaagtgaa
     5101 ataaacaaca caacggcaaa cagaccagtc atgtcctgta ataatccaaa tgtattttct
     5161 aaagacaaag ttgaatgatc tacagcaagc gactgataac tttttttaaa ctctgacgca
     5221 gacatattac ttaaagtaac tgctaacccg ccaaagaaaa tcaaagatag actgccaccg
     5281 accattccta gcaatagttc ccattttctt ttcatttctg aaccccctgc ttttctaaat
     5341 gtatccattc aggtcttttg atcgatgttt cataattgtt attacgttca gagaatttga
     5401 cagtctgttc atttttcttg tcatcccaat tatcccaacc agttgggtga acatgcccac
     5461 ctatcttaca cgcttcaaat aagacatttg catacggacg ccacggtctt cctaaataga
     5521 cgtttctagt atcaggttct gcagtcaagg tacagctttc aaaacgatac cctgtttttt
     5581 gatttttcgg cgtagatgct gctgtgatgt atccaggatt tttactggct aagctatgga
     5641 tatgacactg atgaaaaacg gcatctgccc caccaaatat gaaatccacc gttccttcaa
     5701 tccagcaata ttcataggtc tgacgacaat actcaggatt ggcagaagcc ggtgtacaaa
     5761 aaggagtacc atctttttgc aaatcaggca acggacccgt gcataaggta tcctgataac
     5821 cagatagtcg acagtttttt aaagatacgc gatctcctga attgaataaa gcaacagcct
     5881 gtcctacctt ttctcctgga cctgctgtat tttcgatgtg aagattttct aatacgacat
     5941 tcgatccttc taagaaaaaa gtagcacttc ggaaagtccc taactggcta ccgtcaagat
     6001 actcctgttt tgcaaaacga ttaccggaga taactactgt tcctgctccc acaagtttaa
     6061 aattggataa tctgctttct atatattcat catatcttcc ttcttttact atcaagacct
     6121 ttggatggct atccggcagg cctgccaaat aatcgattcc ttcttggata gtttcaaaat
     6181 ccgtcggggt atctatagca ttctttccaa ttatcagttt gtctttcatc ctcataaatg
     6241 ctcccttatg aattgtttcc aaatatttct catttcttgt gtttccatat gaccgcctgt
     6301 taaagaaaaa gaagaaaagt tttctggact acccattgat tgatactttt tgtccagccc
     6361 ttttctcagc ttcagtacgc cttcgtccaa gcacatcgta tcgttttttc caactaagct
     6421 aagacgaggg cgcggagcga ttttttcttg gattgctaac gttgtataag ctgtcaatag
     6481 atttggcaca tagtaataaa acccatgatg atctaggcgg cgatgtagca aaagtatttc
     6541 gatgtccacc tgtgccgcta gatcaataca aactttgaca cgagaatcca atgctgtcac
     6601 ccaccagctt aataagcctc ccatagaaag accaatcgtt gcgagccgtt gagtatctgt
     6661 gtcttccctt gtctccaaat aatcgatcaa gctgatcaca tcataaatac gcattcccca
     6721 taacgttttt cctgttaata aaaattgttt gaacaactcg ctttcagaaa tacctccgcg
     6781 ttcttcaaat ccccaagcat caatcgacca aacagcatat cccattcctg tcagtacttc
     6841 tgcaaaagat ggagaagcta agtaaggagc accatggatc aattcacttt tcccgactga
     6901 aaaatctccg ccgtgagaat gcaggtaaag gaccggcgga aacggtcctt ctttttctgg
     6961 ataagcatag agggctggta ctgtttccaa ttcatttaag tacaattgat agtattcaag
     7021 cataaaaccg ttttgttttt ctcggtataa tcgttttcca ctaggggtat gtctgctaga
     7081 tggagcacct aaaaaatcat tcaactgcat aagcaaagtt tttacgaaca accagttcat
     7141 ccatattttc tgattgattt gattggaatt tctcaatact gatttcttta gtattttcta
     7201 atagaaatgc tggtccctcg tgattttcaa tcgacatctg gttaaaggaa accttacccg
     7261 caaagccaat ataaaatcct tgtctgctca tttcctctat tcctgtcatc atagcaggaa
     7321 caccgggaac tgcatcttgg gccatcgaga catcgatatt gtcaaatgtg atttcttgta
     7381 tgaattgttc cgctaatcca taaataaaac ctgcagaagc atggacattc cttgccgtga
     7441 tattcgaaaa atggatcctt ctgaatgctg gtgtccgttc atctatcgga taagcctttt
     7501 tttcccatac atacggttct ttccctcgcg gaccacagaa ataataaaga ttcagtataa
     7561 atggacacat cacattatcc atgactatat tggatactcg aatatcttca acgatcccgc
     7621 ctcgacctcg tctagatttc aatcgtattc ctcgatcagt ttcttggaag atacaatttg
     7681 aaatggtaat attacgaata ctaccactca tttcacttcc taatacgaca ccgccatgtc
     7741 catggaccat cgtgcaattt gtgatcgtga tattttcgca agcgatcctt tcgtacgtat
     7801 cttcagtccc tgccttgatt gcaatacagt catctcccac gtcaatatgg caattactaa
     7861 tacgcacatt tttgcatgat tctggatcaa ttccgtctgt atttggtgaa tccgctgggt
     7921 tcaagatcgt caagttatca aacgttgcat tactgcaaag aatcgggttg atcgtccaac
     7981 ttggtgactg gatcaattta atatctttca cagtaattcg atgacagtta tggaaactca
     8041 tcaatttagg acgaggataa gcgagattat ctggttcatt tctaaaagta tgccaccatt
     8101 tttttccatt tccatctaat gtaccgaaac cagtgacaga gatgttctct acattttgag
     8161 catagataca ggaagcataa acttttcgat ggactccttc ccaacgtgaa tgaacaacag
     8221 gataatcttt tggatcgtca gagaatttca gaaccgctcc tgcgcttaaa tgaagttcga
     8281 cattgctttt taaaaataaa gctcctgtta gaaattcacc tgctggaaca actacggtcc
     8341 cgcctccgtc acttgctgca gcatcaatgg cttgttgtat tgcttcagta ttcaattcat
     8401 caattgatgc gccaaatgtc aaaatatcat acatatttat aatgcctcca cttcaatcaa
     8461 tgcttgcaag aatgcaccaa cgcctttttg atcattacaa ataattggtt cactgatgta
     8521 gtaagcatat gaaccatctc gctgatctgc tccgcctaac cctgctactt gacagttttt
     8581 attcaagttc agccagcctt cttttgtttc cagaacaaat tcatcaagta atccttgatg
     8641 tgatttcttc acttgtggaa gccattcttc tttgttcagc agtcccaaac gtattccttt
     8701 agccattgcg taaacaaaca tactactgcc ggaagcttcc agataatttc ctttccgttt
     8761 tgtttctgtt gttacttgat accatgtccc gctgttttct tcttgatatg gaagtaatgc
     8821 agccagtgtc ttttctagaa tttctttcag caaagaacaa tctgtttctt catgaagtaa
     8881 ttcataggta tctgctgcag ccatcaaata ccagccaatc gatcggctcc aaaaatgatg
     8941 ggatagacct gtttttggat cagcccatgg ttggaccttc ttttcatccc atgcatgaat
     9001 cagcaaattt gtttttggat cgaatagatg tttataactg atttcaaact gtctcaaaac
     9061 atcttggtaa tctttttctt cactaaaatt ctggataaat tcagcataaa aaggagaacc
     9121 catatataag ccatccaacc aaatttgata aggataaatt tctttatgcc aaaaagctcc
     9181 ttcggatgtg cgtggatggt ttgccaactg ctgggaaagg agttctgctg cttttttata
     9241 tttttcttcg cctgtttctt tgtacaataa aaagaaaagc tttcctgtat ttacatggtc
     9301 gatattgtat tcttcaacgc tgtagccacg gatcgttcca tcttcttgca cgaaatagtc
     9361 gatattgtct tttatgaaat caaaataaat tttttcttgg gttcgttccc aaagtaattg
     9421 gaacccttta agtacgacgc catagtcata agaccatttt cctttatacc acttttcttc
     9481 atataagcga ggtgttcttt ccatgatact ttttgctaat ttctttgacc agttttccat
     9541 tatttgctct cctttaaaaa ttaaaatagg atttgggaca aataccaaga agtatttgtc
     9601 ccaatcgtct atattactgt gccgctgctt tgtatgcttc ctcgtactct tgtgtgattc
     9661 gatcgcctcc ttgtgctttc cagtcttcta cagctttttt gaatccatct tcgtcaagct
     9721 gtcccatgat gtattgcacc gtagcatcaa tgacgatttt ttcaatttct gatcctactt
     9781 cattgttcgt cggtgaatcc aatggcacag aaggatccat tacagcaaat tcttcatttt
     9841 ctttgatcaa ttgattagag aattcttttt cagggtctgt atctttgaaa gagaacgtca
     9901 cttcactagg acgagagctt gataacggtt gcacctcttg ttgccaaaga tccatatcga
     9961 taaattcgat agaaccatca tcattcaatt cataatgcgt tccttcgata ccgccagtca
    10021 tcaatttata cacatcttct tctaaaagat catcaacaaa ttgaagtaat ttcttcaatt
    10081 gtgcttcgtc ttttacttga gatttgggaa atgctagcaa gccgccaata ccatttcctt
    10141 ctgaccaaac atgataaccg ccgccttcac catctgagat cttgtttaca ggcactaatt
    10201 ccatatcatc ttgaatacct tgacccatcg tcttcagatt cttgatatcc accattccag
    10261 tgtagattcc agttcttcct tgtgcaaatt gttcttgctg atcagtcttt tgggtaactg
    10321 caaagtcttg tgccaaatag ccattctcaa atagatctct tgaaaaattc aaagctttca
    10381 tatactcttc tgtatcaaat tctggagtga atttgccatt atcgtctaca gcccagccat
    10441 ttggtgctcc aaaataagaa gtgaaaagtt taaagctggt ataacgaata tcactaggcg
    10501 cacgatcgcc aaaaccaact gtgtcgtcca caccatttcc atcaggatcg ttttctgtaa
    10561 attgtttagc tacttcataa agctcatcca tggtagttgg aacatctagt cctagattat
    10621 ccaaccagtc ttttcgaatg actaagccag cacgagcgta gtctttttgt atcggtacgc
    10681 cgtacaaggc accgtcgata ctcgcagctt cgattctatc ttcagaaatt tgacttaaat
    10741 ttttatagtc ttttaaatat tctgatacat cccagaatac gcctgatttt aacgcattgc
    10801 ggacagaaga gtttttcaac atcgcaattt gaagtgtaac gatatctcct agttcatcag
    10861 aagccaatgc agttgttaat ctttcttctt ttgaagcatc aggaatccag ttgaatgtca
    10921 gttccgtatc ggttttttct tcgatcaagt tcacaatcgt gtctgtaggc ggtgaagcat
    10981 gatgcaaaat atttaaccaa gtgattttag cttttccatc ttctgtctct gaagaactgt
    11041 tacttgaact gctgccgcat gcggcaagtg ctagaattcc tgcaaaacta agacctaatt
    11101 ttacgagcgt tgcttttttc ataaattttc tccttcactg ttttaataat atttttgttt
    11161 tcttctgttt tttctgtata tgagttcttc cattccaaat ggcaaaatat agaatttgct
    11221 gtccacgtga ctgcggaaaa gaagagactg ccaccgataa aggttaaaac acctggcatt
    11281 gtttggatga tcatcagata aatccctacc atacttaata tcaacactaa tgagtaatga
    11341 agatgtgaga atccgaataa aaatgccatt ttcattttga aaaaatatcc tttccaatca
    11401 taatgagcca tgattgggaa aatatagagt gctgagagca catatatgaa cgcagcaata
    11461 tacaaagcga tcctaagata ccaattgtgt atgaaagaaa gatccacaag taaaacaatc
    11521 ccgatggcgc catatatcca gctcatcagc aaggtttcac gatagttttc tttaaaatat
    11581 gtgaagtacg ttttcgtcaa aggaaacgtt tcttttgagc gcagccattt tctaatcact
    11641 gcaaccatcg catacgatgc aggaccgaaa gtaaaaactc ccaaacctgc gatgactaaa
    11701 ccgccccaca gaaaattcaa ataaaccaac tgtaaaatac gatttagcct tccgtttatt
    11761 ttatctaatg actgcagcat atctttccct ctctttctat cttagtaaac gccgtcttct
    11821 cctagctttt tggcaatctt attagctaaa attaccataa acaatcctac gaccccttta
    11881 aacaatccca ttgctgtact gaaacttaac tgtccattct tcaatccagc tgtataaata
    11941 taggtgtcga aaatttctgc aacgcttcga ttcaatgaat tcaataacaa gtacatatgc
    12001 tcgaacccta agtctaatgt ctgaccgatt tttagaatca gcaaggtaat gattactgga
    12061 cgaattgccg gcaatgtaac atgccatgtt ttgcgtaagc gtcctgctcc atccatttct
    12121 gcagcttcat acaactgtgt atcgactgca gttatcgctg aaaggtagat gatcgtagac
    12181 cagcccaact ctttccagat cacttgtccg atatatactg tgcgtgtcca ttcaggggat
    12241 gttagaaaac tgattttttc aaatcccatt gttgcaagga attcattcaa tacccctccg
    12301 tcaacattca aaaatacata agtaatcgaa acaatgatta cccaagacat gaagtgaggg
    12361 atgtaaatga tcgtttgaat cccgtttttc aatcgtttgt tcgttacttc atttaatagt
    12421 aaagacaaaa tgattggcat cggaaaaaac acgaagatat ttaatccgaa caagatcaac
    12481 gtatttctta ataatgtaaa gaatgtcggt tctgtaaaca aacgaatgaa atgtttgaaa
    12541 ccgacccaag gacttcccat tattcctaaa aatggttgat aatcttgaaa agcaataacg
    12601 agtcccccca taggaagata cctaaaaatc aagaaataaa ggactcccgg cagaatcatc
    12661 acatataaaa atttattcgt tttgattcct gcaattattt tttttcgtct tctgagcttt
    12721 tcttcttttt tcgatagcgt cagttgaaat ggttcttgtt tctttacact ttccataagc
    12781 ccctccttag ttttgtgaat gtttgctgct tatgacttca tgatagataa ctatctgaat
    12841 tacgtatata atcattttta ccgtaagtaa aaacgcttac atagcaatga tttttgtgct
    12901 atacaaaacg ataaagtgta ttttttcaca aataaactac gcatagcaaa ccttctattt
    12961 ttttctatct gacacttagc ataggaaatg attatatacg taatctttca ccgatgataa
    13021 attgaacata tagaaacaga aacatttaat ttattttgag gaggagccta tctatatgaa
    13081 aaagaaagtc tctataggag aaagaagttt tacacttttc aacaatacgt ttctaatttt
    13141 gctagctttg atctgtatcg ttcctttttt aaatatcatc gctacatctt ttgcttctac
    13201 acaagaagtc gtcgcgaaaa agtttatcct ttttcctact accttttctt tagacgcgta
    13261 tcgctacatt ctttctacgc cgaccatttt tagagcactt gctgtttcga ttggtgttac
    13321 aggtgtcgga acgatcgtca gtatgtgtgc aacttcactg atggcctacg gtctttccag
    13381 aaagtatttg tttggtcgag gtttcgtcaa ctttcttgtt gtattttcta tgttgttcag
    13441 cggggggatg attccaacgt tcttagttgt tcgttctcta gggctggtca attcttactg
    13501 ggccatgatc ctgcctgtgg ctgttaatgc aatgaatatg atcattatga gaaacttttt
    13561 ccaagccttg ccggatagtt tggaagaatc agcaaaaatg gatggttgca cagattttgg
    13621 tgtatttttc aaaattatgc tgccattagc gttaccgtct attgctacta tctcgctttt
    13681 ttatgctgtt acttactgga acacttatat gactgctatt ttgtatatca acgattcatc
    13741 taaatggccg atacagattc ttttacgcca aatcgtcatt gtatcaagtg ggatgcaagc
    13801 agaaagtagt gccgttgatg tgattccacc agcacaaaca gttaaaatgg ctgttatcgt
    13861 tattgcaaca gtgcctatgc tgattgttta tccttttgtt cagaaatatt ttgtcaaagg
    13921 agcactcgta ggttctgtca aagggtgatt atgtactgaa cgcaaaatgg tagttgtgtc
    13981 agaagtggtc agcttcaaga aataagaagg catttacgaa aattgcttct taaatttttg
    14041 tgaaatttcg gcttattttt cgaagaatct actcctggaa caccgtgtat cagaggttgt
    14101 gaaagagacg ttcagccttg agcgatgata aaaactctca caaacattgc gacgagtaac
    14161 ccacaggagc aataagaagc gattttgaaa aatagcttcc catatttcac aaaattatgc
    14221 cttattgtcg atagcctgtc tcttgaacgc catttattcg taaaaaagaa ctgtgacaag
    14281 acttttgtca cagttctttt tgcgtgctta gccttgaaat ttaactatcc ataaatacaa
    14341 atactagggt tattctaact tcttttattg cttgaatcag tccacaagaa aaacagcctc
    14401 ttgattcaca aatatttttt tcgatattct cccggcgtaa tcgattcctt ctttttaaag
    14461 aaacgaataa aattttgcgg atttcgatat tgcaatcttt ctgcaatctc ttttacggag
    14521 aggttagtct ctttcaacca tttttttgct acctctaaac gatgattttg aacaaaatca
    14581 ccaaattttt ctcctgtttc ctttttaaat acattactta aatagttagg gttataatgc
    14641 aacctatcag cgatcacatc taaagacaga tcacgatcat attctgtgta gacgatatgc
    14701 ataatattct ccgacaaatt tttaaattca tgatcagtga ttgcttgaga gcattctgtg
    14761 attggcagaa ctaattgttc taaaacaagt ttttctagtt ctttgggatg ataattgttc
    14821 agtgctttta cataaatttg tttcatgtta tcaaagtttt ttgaatctac tcccaataac
    14881 tgtcctaatt gaacgagttc attgatcaag cggaccgaaa ctacttcccg actcaaagga
    14941 tttttatttt gtgcaaacaa tgcatcaatc aattcatgta ctaaattctt cacttcctga
    15001 tttccagaac gaatggcttc aaacaatcga ttttgttctt ctatcggata tctaataagt
    15061 gttttttcat gagcagcagg aacgatttcc tgataaaaaa taattgaact tggaccagta
    15121 tttacacgat aatacagggc ttcttttgcc cgatcaaccg attgcttgct ttcattcagc
    15181 gtttcgaacc ggttactgat gcctatactg atagttaaat tcaagtattc ttttacacgt
    15241 ttttgaatga gtcggcaata ctccatgact tttttgcttg cttctgcatc atctttatcc
    15301 attcgataaa tagtggcttg catttcttca ttcaaaacga tcggcagcat tcgattttcc
    15361 tttggcacaa tttccgtgat catgttgttg atcgctaaaa gtagcaaatc acgctcccca
    15421 ccgtgactat cttctaacag atcgatttga accaaagctg tataatagca gtcattttga
    15481 gaactataac caaattgctg caaccgctga tctagttctc gcctttctac tcgatttcta
    15541 aataaactaa gtacaaatag cgtttccagc tgtggctttt gggtaactaa gtgtgcactt
    15601 aacgcttctt tttctcctat gatccgactg actgattgag cgaccaaatc tagttctttc
    15661 ccactgaatc cttttgattt aagattcaga cgttcctgta tttgagaaat cggacgggca
    15721 aatctgtccg aaaataagta ggaaagaaga ccaatgagtc ctaccagtgt taaagacact
    15781 gcaactagcc cgattctcag attgcggatc attgcgccaa ttgcactaga gtcaacttct
    15841 aatctgtaaa tccaattatt ataatctgat ttcagtacta tatacgtttt atctttttct
    15901 cttatcactt tcagctgatt gtaatctaga tccacgtccg ttaatacagt tggttgctct
    15961 ttatttttta ctgtctgagt agtaaaaagg ttgccaactt cgttttcaat agaaagtatg
    16021 tcttctccac tttcaccaac aacttgttct attgtatgtt tctctatcgt agcaattccc
    16081 aatgcatatt tttctttttc aaacattggc aaagaaatca ccatttcgat tcctttgttt
    16141 ttcttttgcc aaaataaatt atttttgtta tttatgtact tctgttgata cttttcaatt
    16201 tcctcttcgg tcagttgact caacgatcca ttgattactc cccatttacc agccaaactg
    16261 actaaatcat aattattatc atccataaca atcgtttcta taaaatttag ttctttcctg
    16321 atttcagaat aagtggagta atctgtatat gtcagcggat gcttgaatat gtccgagaaa
    16381 tttttggtcg aaccatacgt agaaaacgaa tattcaatcg ttctaatttt ccattcaacg
    16441 ttagttttaa cttgcctgag caaattcttt ttgtctgtta aataactcga ttcgatcgat
    16501 tcataggtat tctggtaaat gaataaacta aatcctatga caagtacggc tcctaataaa
    16561 aacatcggta aaaatatttt ataaaatact gtacttttct tcattttctt cctctcctcc
    16621 ttttaaaata aaaggctttc atttttctgt aaaattgata ctcatctaat taaatgagca
    16681 ttccccgctt tcaagaatag cataattaaa aataaaaatc caagtaattt ttaacgtgtg
    16741 caatcttttc atatcaaaga tctattgact tatcgtagtt atcgtaatat gatgaatgcg
    16801 ttaacaaaaa gtgaaaaagt aaggaaaatg atggaatggt aacgatcaaa gatgtcgcta
    16861 aagcagctgg cgtttctcat acgacagttt ctcgtgcttt gaataacagc agtttaataa
    16921 aaaatgaaac aaaacaaaaa atacgacaac tagctaagga aatgaattat tcgccaaact
    16981 atagtgcaaa aggtttagtg aatcaaaaaa aatatctaat cggactattt ttctcaagtt
    17041 tgcataaagg aacttcatca aatttcctag cagattccat tgcaggcatc cattcagtat
    17101 tagacacaaa ttacagttta tctgttgaaa gtatcgatgt tgttgattta acagaaatca
    17161 acctgcaacg ctacgatgga ctgatcgtta tgagtcaaag tgatgatgat cagcctttca
    17221 tcgactatct caaagaaaaa gaatttcctt tcgttgttgt caatcgtcac atcaatgatc
    17281 cagcggttat caacgtcact gccgatgatg cggccggtgt tatgcaggca gtagattacg
    17341 gtattggatg cggacatacg aagatcgctt atattggcgg aaagaaaaat tttcgttcga
    17401 caaaagaacg ggaaaaaggg gtattgaaaa gtctaaaaaa agcgagcatc cctgtcaatc
    17461 cagcctattt tttaacagga gattacagct tagaaagcgg cctccaaaac atggaatacc
    17521 tattatcact ttctgacctg cctactctgg ttttttgcgg caacgacgac atagcgattg
    17581 gtgcattgag agctgtacat ttagctggcc tccgtgttcc ccagaacatt tctctgatcg
    17641 ggttcgatga ttctccagtc gtctcctatc tcaatccgcc gcttaccacc gtacgtaagc
    17701 ctttgaaaga aatgtgtcaa gaaggaacaa agcttttact agatttgatc gaaggcagga
    17761 cgatcgaaca atctaaaatt gagctctcca ccttgttgat ccttcgtgag tcgatcaatt
    17821 acttgtaaac tacaagtaat tttatataaa aatgttaacg tgtgcataac acagaaagga
    17881 agtttatatg aaaaaactga caaaagaatt agtgaaaaaa aacgaagcac ctgtaaaagt
    17941 tcttcagttt ggtgaaggca attttatgcg tggatttatt gattggcaga ttcagcagct
    18001 gaataaccaa caattgttta aaggtaatgt tgcaatcatt caacctttag aacaaggtct
    18061 tggaaatatg atgaaccagc aagataattt atatacggtc attttacaag gactcagcaa
    18121 tggcgaaatc gttgatactt ccgagattat caccgtagta gaacaaatga tcaatcctta
    18181 tgatgaatgg gatgcttatc tatctctagc agaaaatgac gacttggcct atatcgtctc
    18241 caatacaaca gaggcaggaa tccaattcgt ggagactgat aatttaacag atactccccc
    18301 acagagcctc ccgggcaaac tgacagcctt tttataccga cgtttcaaat taaacaaagc
    18361 tggctttacc atcattcctt gcgaactgat tgacagaaac ggcgaacgtc taaaagaaat
    18421 cattttacgc tacgcagaaa aatgggattt agaacctgct tttgttgagt ggttagaaaa
    18481 agaaaatgtt ttctgttgta gtttagttga tcgcatcgtc ccaggttatc ctcgcgaaga
    18541 tgcaggtgtt ttcaatcaac ggcataacta tgaagatcaa ttgatggtca aagcagaacc
    18601 attcatgctt tgggtgatcg aagggcctaa agaattggag aatcaactac cattcaaaca
    18661 ggctggcttg aatgtcatca tcacagatga tatgactcct tatcgtgaac gtaaggtgca
    18721 tttgcttaat ggaccgcata cagcgatggt ccctcttgct ttgttggcgg aattggaaac
    18781 tgtagaagaa gtaatgaaag atcctttatt ctccgcatat gttgatcagt tattcaatct
    18841 agaattgatt cctatgcttt ctttacctaa agatgaatta gccatttatg ctgaccaaat
    18901 caaagaacgt ttcttgaatc cttttgccca tcacaaatta gaagcgattt cattaaatag
    18961 tgtttcaaag ttcagcaccc gtctgcttcc agtgttcaag aagtatatcg aagaacaaaa
    19021 tcaggtacca ccgttaatca ctgtttcact agctgcgcta cttcttatgt atcgaggcga
    19081 tcaagtaaag ccacatgatg atgaaaagac gataagcgaa tttactgatg cttggtctga
    19141 taatggaaca gctattcctc gattattgca aaacgctgcg ctttggggag aagatttgtc
    19201 tcaaataccg aatgtgacag atacagttca agaaatagct gcaaagatcg atcaaaaagg
    19261 tgtccggtca gtattacaag aaatgaaagg aacgatggtc catgcttgaa accctgcaac
    19321 caacaatgaa attaaatcga cgagacagtg tggtcgtcgc attaacccct attccaaaac
    19381 aaacacaact gacgattgat cagcaaacga tcaccactct tgaagatatc ccgcaaggtc
    19441 ataagattgc attgggtgat ttgaaagctg gagacaacgt gatcaaatat ggctatccaa
    19501 tcggtcatgt gacgacagac gtaactgccg gtcaatggct gcacactcat aatgtaaaaa
    19561 ccaatctttc tggtgaattg gattatcgat atgaaaaaga tgtccatcca agtcattacc
    19621 tttttgagaa ccgaacattt caaggttact tgcgaaaaaa tggaaaagta gggattcgta
    19681 atgatttgtt tttagtacct accgttgggt gtgtgaatgg cattgctgaa ctgatcgtca
    19741 aacagttcaa ggaaaaacat ccagatctgg gacagtttga ccatattacg attttaaagc
    19801 atccttatgg ctgttcgcag cttggaaaag atcatcaaaa tactcgagaa attttagcgg
    19861 acgcagtaaa tcatcccaat gccggaggag ttttagtatt tggattaggt tgtgagaaca
    19921 atacagttcc tgaattcaaa aaaattttag gtgaatatga tgaagaacga gtgaaatttc
    19981 tagtggctca agatgtttac gatgagatcg aacaaggtgt ggctctatta gaagagcttt
    20041 taacagcggc ggaaaatgac cagcgcatat cagtcccgct ctctaagttg aatgtcggtt
    20101 tgaaatgcgg cggttctgat ggtctatcgg gaataactgc taatccttta cttggtgcat
    20161 tttctgacta cttgattgct caaggaggca gcacgatctt aacagaagtg ccagaaatgt
    20221 ttggcgcaga acaagtattg atggcacgag cggaaaatga agaagttttt gactcaatcg
    20281 ttgacttgat caatgacttc aaacagtatt tcttgtctta cggggaacca gtttacgaaa
    20341 acccatctcc tggtaataaa gcaggtggga tcactacatt agaagataag tctttaggct
    20401 gcacgcaaaa atcaggaagc tctcctgtcg ttgatgtgct acaatatggc gaaaaaatca
    20461 gaaaaccagg gcttagttta ttgcaagctc ccgggaatga tcttgtagct gcctctgctc
    20521 ttgcttcatc cgattgccag ttggtcttgt ttaccacagg aagagggact ccgtttggct
    20581 catatgtccc aacggtcaag gtatctacga atacaactct ttttgaacgc aaaggtcatt
    20641 ggatggattt taatgcaggc gtcttattag aacaaccaat ggaagtaatc ttagaatcgt
    20701 ttgttcaaaa aatcatcgct gtagctagtg gagaagaaac gaaaaatgaa caaaatgacg
    20761 ttcgagaaat tgccattttt aaaaacggag taacactttg attttcataa aacagtataa
    20821 aaagaaagaa ggaagattta tgtttttatc tgatgatttt ttattaaaag acgattgggc
    20881 gaaaaagctt taccattcct acgcaaaaaa catgcccatt attgattatc actgtcactt
    20941 agatccaaaa gaaatttacg aaaacaacaa tttcagcaat ctgacagaag cttggttagg
    21001 aggcgatcat tacaaatggc gcttgatgcg agcttgcggc gtgcctgaag aaaaaatcac
    21061 aggaaatgct tctgattttg aaaaattttt agcttggtgt caaaccgtac caaaaattat
    21121 cggaaatccg ctttacagtt ggtcacatct tgaattgaag cgtttcttcg gtattgactt
    21181 gttgataaat gaagaaaatg cagagaaaat ttggacacaa gcaaatgaaa ttttggcagc
    21241 tcctgatttt cgccgtcggg aaatcgcaaa aaaatcgaat gtagaagtga tttgtacaac
    21301 agatgatccc gcagacgact tgcactatca tcagttgctt gctcatgaag aaccagattt
    21361 gaaggttcta ccttcattcc gtccagataa agcactcaat attgaaaaag aaggatttaa
    21421 tgcatgggtc acactactgg aagaagcagc tgaccaaacg atcaccacct atcaagaact
    21481 gatagaagtc ttagggcagc ggatagaata cttccatcaa catggatgtc gtgtttccga
    21541 ccacgcttta gacatcttac gctataaaga agcggatgaa acagtattag aagagatttt
    21601 tcaaaaagca cgagctaaca aactattatc ttcagatgaa atcgatgctt atcgtacaga
    21661 aacactgata catttgaccc acttctatca ttctcataat tggacgatgc agctgcacat
    21721 ccatgcttat cgtaactgta atacacaaat gttggaaaaa ttagggcccg ataccggcta
    21781 tgatggaatg aatgatcttt ctttgactat tcctctgcaa aaattattga accgtgcaga
    21841 agaaacggat cagttgccaa agacgatcct ttattcattg aatccgaatg actatcctgc
    21901 gattttagct ttgatgggct gtttccaaaa agaacagaat ggaaaactgc agttaggttc
    21961 tggatggtgg tacaacgata ctcgagctgg tatgcgcgat caattgacac aatttgctga
    22021 tggtagtgct ttggggaatt ttgtcggcat gctgacagat tcaagaagtt tcctgtccta
    22081 cactagacat gaatatttcc gtcgtgttct ttgtgaattt ttaggcgaaa tggtcatgcg
    22141 aggagaagca cctgaagatg aacaactttt aggaagtcta gttcaagcga ttagttatac
    22201 aaatgctaaa aattactttg gcttttttgc ctaattgatt aatagtaaca gtaacgaatc
    22261 aaaaacagga tagtgaaata acggaatccg tttatccacg ttttagagaa gaagacggac
    22321 caaatttgct ccgtcttctt ctcttgctgt tctgcttcat tgcctataaa cctttatgaa
    22381 agaagagata acatgcctac tatccatatt gccggtgatt ctactgcggc agaaaaagat
    22441 gaaaacaagc gtcccgagac aggttgggga gaaaaaatct ctgcttattt ttcacccgag
    22501 atccagatca ataaccaagc aaagaatgga cgcagcacca aatcatttat ccaggaagga
    22561 aggttagccc gtctagcttc acagtttcag ccgaatgatt tcttatttgt acaatttgga
    22621 cataacgacc agaaaatcca agaagaaaga ggtacgcttc ccttcggtag ctatttaaaa
    22681 aatctgcaga tattttttga atgcgcaaaa aaagcgaacg tccaaatggt cttactgaca
    22741 tctgtgacgc gacgagatta cttagaaaac ggaacattga atccagatat acttggagac
    22801 tatccaaaag cgatgcgtgc atttgctgag aaacaccata ttcctctttt agatgtgttc
    22861 tcaagatcac aagaattgtt ccagaccttc tcaaaagaag agacaaaaaa attctacctg
    22921 catcttatac ctgatacttg taaaaattac ccagaaggac taaaagacaa tacccacttt
    22981 agtccagaag gcgctgataa agttgcccga ataattgttg aattgataaa agaatcccgt
    23041 ctgcctcttg ctaattattt acaaaaagga gtttgagatg tttccattaa atttaggcat
    23101 ccgtgcccac gatttagatg ttcgaaatcg tgaagaaatc gttcaaaaag tatcacagct
    23161 tcacttgtcc catatccaat ttgcaccaca aaaagcattt cctgaacaac ttaaattaac
    23221 tgacatgaca cttgggagtg ctgcctattt tggtgaatac ttccaaaaaa acaatatcga
    23281 actttccatt ttaggatgct atatcaacct atccagcaaa aatcaagaag ttcgtgcaca
    23341 agcattggca actttcaaac agcaaattgc tctgtgctct gcctatcaag ccaagatgat
    23401 tgctacggaa accggtagtg tctctgtcgg ttacacaaaa gaaaatttta ctgaagaagc
    23461 ttatcagatc gccagaaatt ctatcattga attagtcgct catgcagaaa attttggcgt
    23521 aactgttgct gttgaagcag ggatcaatca tccaatctat aactatcagt tagctaaacg
    23581 tttaatcgat gaagtagctt caccaaattt aaaaatcatt ttagattgtg cgaatttgat
    23641 gcataaagaa aatcatgctg atcaggaaaa agtgatccga ggtgccttgg acaatttaca
    23701 tggttatatt acagcgcttc atctcaaaga ctatatcatg gaaaatggaa agatccgcat
    23761 ggtacctgtt ggcaagggct gtttagattt ccgcccggta ctgcattata tcaaatatga
    23821 gcgtcctcta atgtacgcca ctcttgaagc tactcctgag atttatgttc ctgaagcaat
    23881 agaacacttg cagtttattt accaagattg ttaaggagaa gattatggag gaacgaatac
    23941 agaaaagtta tcaaaaatat catgcaaatg cttttcagac attgctgcat ctttatcagg
    24001 gaaattattg gcgttttgcc atgtcaggac tcttttttat tatcaaacat cttccatctt
    24061 ggttaatgcc gatcgctatt gccaatgtaa tcaatgcagc ttcatcgaaa gattcttctc
    24121 agttgcaggc catttatttc aacgcttttt tgatggcttg tctgattggt caaaatatat
    24181 tgacgaatta ttttcatgta aaataccata gcacttcgat ccgtcaagta gaagctggac
    24241 taagagcgac ccttatcaag aaaatccaag aactatctat tccttatcaa aaagaattgc
    24301 aatctggacg aatccagtca aagatcatcc gtgatgtaga agctatccaa acgttgtcct
    24361 ctcaagtatt tgtcagcgga ttaaatatcg ctgtcaattt attcgtagct ttaggtatca
    24421 cgctttataa aagtcctgtt gttttcatgt ttttcttatt gactgttcct ctcgccgcat
    24481 tcgttactct ctttttccgt aaaaggatca gacagtccaa ctcagacttc aggcaagaaa
    24541 tggaagagac ttctgcaaaa gtgatcgaag tgatcgaatt agcaccgatt gctcgagctc
    24601 atgggttaga aaaacacgaa acaactcgct taaataagca ttttactcaa atctatgaaa
    24661 aaggattcca cttagatatc ctgcaatctg ttttcggatc agtcagctgg gctagttttc
    24721 agatatttca gctgatttgt ttgattttca ctgggatatt agctttacaa gggcgcatcc
    24781 aacccggcga tgtcgtgatg tatcagacgt atttcacgac gatcgtcaat tccgtttctg
    24841 gaatgatcac gctgattcct acgatttcaa aaggcatgga atctatcact tctattggcg
    24901 aactgttgat tgctggcgat gtagaaactt atcacggtaa gaaaaaaatc caacatttgg
    24961 atggaaattt tcgttttgag gatgtttctt ttctttatcc ggactcactc aaaccgatta
    25021 tcgatcattt ttctctagag gtgaaagctg gagaaacaat tgcttttgtt gggccatctg
    25081 gctctggaaa atctacactc cttaacttat tgattggatt tatccagccg acttcaggaa
    25141 aaatttttct agatgatcag cctttggatg aactggatat gcgaagtgtg cgaaattatt
    25201 tagccgttgt tcctcaaacc actttgttgt tctccgcttc gatcaaagag aacatcactt
    25261 atggcttgaa aaacgtatca aaagaacgtt tagatgaagt catcgaagct gcgcaacttt
    25321 cttcactgat tgaccagctt cctgatggtc tggatacctt agtaggcgaa catggcaaca
    25381 agctgtctgg tggccaaaag caacgtatct ccattgcacg agcgttgata cgtcagccaa
    25441 aaatcatttt gctagatgaa gcaacctcag ctttagataa ccagtcagag aaaaaaatcc
    25501 agcaagccct gaattacctg acagaaacac ccactacttt tattgtggct catcggcttt
    25561 caacgatcaa agaggcagat aaaatcgttg tgatcgatga aggaaaaatc gttgaaatag
    25621 gtacttacga aaaactgtta gctcaaaaag gctatttcta ccgcttgaaa aatgaatgac
    25681 aaaaaatagg agctatgaca agacttttgt cgtagctcct atttctgaat aaacggtgtt
    25741 ctcctgccaa ctcctcggtc acaagtcaca atagtcatca aacatgagaa gctgtttttt
    25801 gaaattgttc cttgtaactc agagttaaac ggtaggctca cgacctcttg gtaaatggtg
    25861 ttcaagagac agcctatcgg caataagaag caattttgtc atcgctcaag gccgaacgtc
    25921 tctttcacac cctctgttgt ttcataaaat agttttattc gctgtaaagg tcgcgaactg
    25981 gtgtcatgat gatacggttc aagtcattga tgattgtact gaagccttgc tctttttgca
    26041 tcaagtcatt gattacttct tctgattgga ttttcacagc catttcttgt gctttcattg
    26101 catcttcgtc gctgaactct tgtccactca tttgtttttc ttgtaattcg atttgcatcg
    26161 cttggaagtc tttgaacagt ttgtgtgctt cttcgtttgc ttgtactttc tcgtacgctt
    26221 ctttcaacgc tttgaattct ggtaattcac ggatctcacg ttcgatttga ttcgcgctat
    26281 cgtagatgtt tgacatgtta tgccctcttt tcttttagta gttactctct attgtaacat
    26341 ggggttattc gttttcaaag gggctactct ccttgatatt tccgccagag gtctttagcc
    26401 gcttcaccaa ttccctgaac gccttctttc accatatcgc cgaagttttt cagcccttct
    26461 tttgcttgtt caccatattg attcaagtta tcttgccaat ttccagactc tccattagaa
    26521 tttcctgtgt ttccaacttg atctgcagct accacttgtc ctcctgtggc ataggcatct
    26581 gctacactaa atcctgtttt tgaagtatac ggaaggatgc cttctgccgc tgatttgaag
    26641 actttcccga caacatttcc acttgtccct tccaaatagt gcagcttgct ggattcttcg
    26701 taacccatcc atgtcgaaat cactacgtct ggcgtgtaac cgatcatcca ttggtcattt
    26761 gcttttgtgg catcgaaatt agtttctgtg gttcctgttt tccctgctat cgtataacct
    26821 gcaggattcg cagcagccgc tgttccattt gaaaatgtac caagaagcat gctggtcatt
    26881 tcatcggctg tttcctttga tatgacctgt tttggttttt tgtttgtgtt atcgacgatc
    26941 accgctccag tcgaatcaac gattttcgtg ataagatgcg gcgtatacat ctgaccatca
    27001 ttggcaaatg cactgtaagc acccgccatg atcaatggag atactccttt ttccagtcca
    27061 ccaagggcta agccataata cttatcagat tttgctaaag gcaggccgaa ttcttctgct
    27121 ttatcatatc ctttttgtaa accgatctca tgcaaaagcc atacagtagg caaattcaaa
    27181 ctttgtgcaa cagcttgata catcggtact tctccttggt atgtcccgtc aaaattatgc
    27241 gcatcgtaat aactttgcgg ttcgtctttc aagatactgg aaggcttgta tccagcttcc
    27301 agtgctggtg tatatacgct taatggtttg atcgttgatc ctggtgaacg acgcatctgt
    27361 gtagcaaagc tgaatcctct aaagacatga tctcctcttc gtcctactag tgcttgtaca
    27421 ccacctgtat tcggatctaa agctactgaa gcagattgga ccatggcacc atctgaagca
    27481 tttgctggga ataatgcact gttttgataa gtagcttcta attgcttttg ataatcctga
    27541 tctaaagctg tatagatttt atagccttta ttcatgacat cttcttcatc aagaccatac
    27601 tcgttaactg cttcatcgat cactgcatca aaataataag gataacgata accagaatct
    27661 gaattatcgt atgtgtcatt aagatacgcg ctgatatctg tctggctttc tgcttgttct
    27721 tgttcttttg tgatttttcc gttttcttcc attacactta gtactgtgtt tttccgatca
    27781 ttcgcatttt ttgggtgatc gatcggatta taaataccag gacctttcag cattcctgcc
    27841 aaagtagcag cctcagacag cgtaacattc gttgcatcta ctccaaaata ctttctggaa
    27901 gcgtcttgga caccccatac cccgttgcca aaataggcat tgttaagata catggtcaag
    27961 atttcttctt tgctgtactt cttttcgatc tcgattgcca aaaataattc cttcgctttt
    28021 cgatcaaacg tttggtctaa tgtcagatac gcatttttgg caagctgctg agtgatcgta
    28081 cttcctccgc cccctgatgt tccgccagac aagaccattc ggactgctgc acgggcaatc
    28141 cctttgatat caaacccgtg atgctcgtaa aaattcctat cttctgtcga gattactgca
    28201 tcttggatat agggagaaat cgcgtttaat tctacatatg ttcctttttg ggcgtacagt
    28261 gtgccagctt cttcgttttt cttatcataa atgactgtcg attggcttaa tcctgatttt
    28321 aacgtttcga catttgcttg ttttgctaaa ataaagaggt agatacttgt cactaagaca
    28381 cagatcaaac caatcagcaa aatcaatttg ttcacatgat attttttcca gatgcgcttt
    28441 cgccatcgat ggaattgtcc gagatatggt ctgatccaac gccaaaaact gatcaaagca
    28501 gcttttatct tttctaaaat gctttgaaaa tccatttgct tcttctcctg tctatttgat
    28561 tcaatcgtct tattttacca tagtgaaaga gtgttttctt cctgcttaag ttgtagttca
    28621 atatgttttt ttacgttagt gcaagtagag taacataaga atgaacagaa aaatgtaagt
    28681 tttttcttaa atatgtttta aaaatggtac aattagtctg cgattgcact gaaaggagta
    28741 cacttgtgaa aatcacgatc actttaccta tgaaccatcc tgaaacaaca attcgcgact
    28801 tgcttgaaaa ggaatggtta gttcctagaa aggttcgaca ctttttgcgt atacgtaaaa
    28861 acgtttggat caatcaacaa cctgctttgt tccatcatga agtaaagggc aatgaccaga
    28921 tcacattgtt attcgaagaa acagattata attatcaaga agttcaatta ggagatgcga
    28981 agcacatccg tgttttatat gaagatgagc atttgattat agtggataag cctgcaggaa
    29041 tgaagactca tccaaatgaa ccgacagaaa acagtacctt actcaatcat ttagctgctt
    29101 atctcgacac taaacagcaa cgaccttacg ttgtccaccg cttggacaaa gaaacaagcg
    29161 gtgccgtttt atttgcaaaa aatccatttg tcttgccgat acttggaaga atgttggaac
    29221 aaaaaatgat ctatcggaga tatcaagcca tcgtatgggg agaaattgcc aaagatatga
    29281 ccatcaccaa taaaattgga cgagatcgcc atgatcggag aaaaagggtc gtagatgata
    29341 aaaatggtca gagcgccttg acacatgtca ctgtcaacaa agtactttct gaacaaacac
    29401 aagtctattg tgttttggaa accggacgta cacaccagat cagagttcat ttagctcata
    29461 agggacatcc gatcgttgga gaccctctct accaaaatag aacagctgaa cgactgatgc
    29521 tccatgcatt agaactgcac atgatccatc catttactca agaaaaaata gtcggtaaag
    29581 ctttacctgg attatgggaa tagaaataaa aaagaacaga gtcttatcag cagataatga
    29641 taagactctg ttctttttgt gtaatttgtc tgcttacttt tgatgttcgt gttctgctaa
    29701 cagcaaacta ccgataatcc cactttcatt cggcagtccc caacgaacga tatattcact
    29761 tacttgaggt gtttccatat aaccacccat caattcaaca aattgctgac ggattttttg
    29821 aaggagatga tcctgattca ttaccccacc gcctaaaata atcttttcag gtgctaacgt
    29881 caacgtatag ttgatcagtg cttgagcaat ataataagcc tgaatagccc aaacaggatg
    29941 atcttgcggc agatcttgcc ctttgatccc tgtgcgtgcc tcaatagacg gtcctgctgc
    30001 taatccttct aaacaatctt tatgataagg acaagtacct tcataatggt catctggatg
    30061 gcgtttcacc caaatatgtc ccatttcagg atgtgcgatc cctgaaaaaa tttcttcatt
    30121 gatcacgaca cctgcaccga ttcctgttcc cacggtaagg taaatacaac tattttttcc
    30181 ttgtgctgct ccttgcttca attccccata tgcagcagca ttgacatccg ttgtccaagc
    30241 agcaggaata ttgtagcgtt ccttgattgt gccaagaaaa tcgaattgtg cccacccttt
    30301 tttgggagtt gccaaaacgt atccgtaatt atcttttgtt ttgtcgatac caatcgggcc
    30361 gaatgagcca atcccgattc ccttcaattc ataacgatca aaaaattcaa atacctgatc
    30421 caatgtttct tctggtgttg tggtagggat acttaatttt
//
LOCUS       DAZKCH010000030        29007 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000030 DAZKCH010000000
VERSION     DAZKCH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.030"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..736
                     /locus_tag="ACG84X_001336"
     CDS             <1..736
                     /locus_tag="ACG84X_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen binding domain-containing protein"
                     /protein_id="HFP9127223.1"
                     /translation="KANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTT
                     GADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTPGG
                     VVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQA
                     PTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGETI
                     ISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1089..1937)
                     /locus_tag="ACG84X_001337"
                     /pseudo
     CDS             complement(1089..1937)
                     /locus_tag="ACG84X_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2090..3202
                     /locus_tag="ACG84X_001338"
     CDS             2090..3202
                     /locus_tag="ACG84X_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFP9127224.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3280..3573)
                     /locus_tag="ACG84X_001339"
     CDS             complement(3280..3573)
                     /locus_tag="ACG84X_001339"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFP9127225.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3741..4055
                     /locus_tag="ACG84X_001340"
     CDS             3741..4055
                     /locus_tag="ACG84X_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFP9127226.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4076..6055
                     /locus_tag="ACG84X_001341"
     CDS             4076..6055
                     /locus_tag="ACG84X_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFP9127227.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6068..6394
                     /locus_tag="ACG84X_001342"
     CDS             6068..6394
                     /locus_tag="ACG84X_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFP9127228.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6410..6928
                     /locus_tag="ACG84X_001343"
     CDS             6410..6928
                     /locus_tag="ACG84X_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127229.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6928..8280
                     /gene="celB"
                     /locus_tag="ACG84X_001344"
     CDS             6928..8280
                     /gene="celB"
                     /locus_tag="ACG84X_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFP9127230.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8364..9869)
                     /locus_tag="ACG84X_001345"
     CDS             complement(8364..9869)
                     /locus_tag="ACG84X_001345"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFP9127231.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9961..10551)
                     /locus_tag="ACG84X_001346"
     CDS             complement(9961..10551)
                     /locus_tag="ACG84X_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9127232.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10730..12376
                     /locus_tag="ACG84X_001347"
     CDS             10730..12376
                     /locus_tag="ACG84X_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HFP9127233.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12425..13144
                     /locus_tag="ACG84X_001348"
     CDS             12425..13144
                     /locus_tag="ACG84X_001348"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFP9127234.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13623..14570
                     /locus_tag="ACG84X_001349"
     CDS             13623..14570
                     /locus_tag="ACG84X_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127235.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14582..15502
                     /locus_tag="ACG84X_001350"
     CDS             14582..15502
                     /locus_tag="ACG84X_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127236.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15543..17000
                     /locus_tag="ACG84X_001351"
     CDS             15543..17000
                     /locus_tag="ACG84X_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9127237.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17345..17959
                     /locus_tag="ACG84X_001352"
     CDS             17345..17959
                     /locus_tag="ACG84X_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFP9127238.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17952..19676
                     /locus_tag="ACG84X_001353"
     CDS             17952..19676
                     /locus_tag="ACG84X_001353"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9127239.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19673..21124
                     /locus_tag="ACG84X_001354"
     CDS             19673..21124
                     /locus_tag="ACG84X_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9127240.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21597..23750)
                     /locus_tag="ACG84X_001355"
     CDS             complement(21597..23750)
                     /locus_tag="ACG84X_001355"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFP9127241.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23752..24798)
                     /locus_tag="ACG84X_001356"
     CDS             complement(23752..24798)
                     /locus_tag="ACG84X_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9127242.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24948..26237
                     /locus_tag="ACG84X_001357"
     CDS             24948..26237
                     /locus_tag="ACG84X_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFP9127243.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26250..28952
                     /locus_tag="ACG84X_001358"
     CDS             26250..28952
                     /locus_tag="ACG84X_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFP9127244.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
BASE COUNT         9431 a         5015 c         5874 g         8687 t
ORIGIN      
        1 gaaagcaaac cgacttacac caggcggtgt cgtgttgaca aagatcgatg accaaagcgg
       61 ggaagtcctg caaggagctg tttttgagtt acaagatgcc aatggaaccg ttctgcagtc
      121 aggtctaacc acaggagcag atggaaaact ggcgattgac ggcttagcac caggagtgta
      181 tcagctggta gaaacccaag cgccaacggg gtatgaattg gatgcgacac caatcgagtt
      241 tgagatcgaa agaagtcaga cagcggtggt agaattgacg aaagaaaatc gacttacacc
      301 aggcggtgtc gtgttgacaa agatcgatga ccaaagcgga gaagtcctgc aaggagctgt
      361 ttttgagtta caagatgcca atggaaccgt tctgcagtca ggtctaacca caggagcaga
      421 tggaaaactg gcgatagatg gcttagcacc aggagcatat cagctggtag aaactcaagc
      481 gccaacgggg tatgaattgg atgcgacacc agtaactttc aagatcgaaa aagaacaaga
      541 agtggcgatc tttttaacaa aagagaatag aaaagttgct gatagctcag atataagagg
      601 aaacaatcca acaagcagtg gaaataagca tcttccaaaa actggagaaa ccatcattag
      661 ccagtttata ttgtcaatat tgggtgtgct acttgttttc atcagtataa aatttagaaa
      721 gaaacgaaat atatgagcta aaataaaaaa ttgaataagc atagttttta aaatcaacta
      781 gtacccatca attgaatgga aactaccgat tttagaaggg gtatacaaac aaatattagt
      841 atcggagtag agaaggttga acccaaccag taaataagta aagacaattt tgtgctgcgt
      901 tgagaagtga aaaataaacc tttgtagtaa tactagttaa taaaaaatat acaaaaacac
      961 tgcgaaaatc attcttgagt ttcgcagtgt tttttgccta atgactcaag tttattgggt
     1021 aatactttga ttttctttct acaaataatc agcgatcagt tgtaattttt tctctagttt
     1081 taatggctct ttgtcaataa ggagaaaaac aagtcgggtc ttttgtctcg gaaagcttca
     1141 accaactcgt gaataaaggt tacgcctcct tgaaaggcgt ggaaaaacca agtaatcgat
     1201 caatcaccaa tttcgcattt ggtagaacat gtttggtgag ctgaaagtag gtggcgttca
     1261 tgtctgtaac taagaattct atttctttag gattagtgca gctaaggaaa tagtttgtta
     1321 atcgaggaat tttttgtgta ggtaaatttt ctcgattaat ttttctgtct cgccatccgc
     1381 ggaaataaaa ctcagtttat cctcaacgga aacgtgagaa cgaaattcac aaccctcaac
     1441 actcaagaca gaattctttt ggaagacttt ggtaaatagc ttctcaactc tttcaatgtg
     1501 cgaataacgg ttgtcaaaga tacctaacaa cttttcgaaa taaaaaataa cgacactttt
     1561 tcagtcagta aagaagtgat tttatgtctg acatgatttg aaatcgagtg ccttggacgg
     1621 ataaaataac tttgagcgtt ccaatggctt cgacagtttt tacaggtata gcgctgcttt
     1681 tttaggcgta taaccattgg catatgatta tattattcaa agtggacaat ggtttccttc
     1741 ttcttgtttt tcaccaccat taatttccta tttccatcta ccacagcaga accacaattt
     1801 ctacagacac atggagcagg gaagagaact gcagcaacga tcaatgtttt tttcttctgt
     1861 aaggtttcgt aagagacctc tgtaatcatc aaatttttgt ctattgatct cagaattttt
     1921 ttgatagaac cattcataaa gcatatcgtt ctctcagttg tttattttgt ggtgatttaa
     1981 tcatacaaga aaacgatatg tttttttata aaaacatgaa taggaaaaat agttgacaag
     2041 aaaatgacaa cgccatatga tgttccatag tatttacaac ctgtcataga tgactgtaaa
     2101 aaataaaagt aaaaagaaag gacgacaaca ggtggatttt tatcagtctc tacaactaga
     2161 tccgtttatt ttaaaacaaa aaatacgaga agcagcttct aaaaaagaaa agtgcatgta
     2221 tatttgttca ttgtttttac gatcattatt catcgtattg tttgccattt gttttatcat
     2281 tataattaca acattatttg aatcgaagca taaaccatac gctgtggttt tattctgtat
     2341 gttgatgagt attcgttttg ttgactttgg ttataagatt tcccattcga tcataggttt
     2401 agcaatcgtc atgttctcac tattagtagc accgtatgtc cagctgatca aatggtcagt
     2461 tatgggcatg ttgattcatt ttattttact aagcagcata ttaatggcaa ccgctagtga
     2521 tcccaaaatg gggaatgctt ctttgtacgg cttttcatat ctctttattg tttattcgtt
     2581 acctaaagat tcgttgaaca agaatttctt tacacaaaca agtagcttat tatttttgtt
     2641 tttttgttgg ttttcagttc tcctttacag aaaacatcga gaaaagaaca aagacaaaag
     2701 cttgtttaaa gagatttttt tgaaaggcat gtattcgcag gaaaaaattt ggatgctcat
     2761 ctatgcattt ggcattagtc ttttgatcgt tgcaggagag tatgtccctt ttcagcgatt
     2821 gatgtgggca gggtttgcat tttcttctat tgtatctagc tatggattga tgtcgattgg
     2881 tttcaaagaa cgagcagtag accgaatcat tggctcattg attggatgtg ttttatttat
     2941 tggtatcagc caatttattc cttttaactg ggtcggtata ttaggtggtc tagctttagg
     3001 tgtttgttct acctatagat ataaaacagt ttttaattct tttggtgctt tggcaatcac
     3061 tgccagttta ttcggggttc caggagcagt aacgatccgc atttttgaga atatccttgg
     3121 ggtatgttta ggaatcatgt atattggggt gactgaaata cttatccgaa aaataagaga
     3181 aaaacacggt ttgaatcatt agatgagatc gaataaaaaa taaggaaaaa gtgaagatac
     3241 acatggatga taaattgcta tcattccatg tgtatctttt tacggtaaat cagtgaaacg
     3301 ttcgactttc atttttaatt tatacttttt acggagttcg tttatttgag ccatcatttc
     3361 ggatttgtga tgcttttcga ttgcttcttc atctttccaa cggtcgatca gtaaaagaga
     3421 ttctggatct tctagtggaa agtaatagtc atatttctcg tttccttctt ctgcacgaat
     3481 cgctttgaca atgtttcttt cgaccatttc ttctgcaaat tttctggctt gtccatttgt
     3541 acttgtatac aaaatattca ctgtgatact cactaaatcc cctcctgaaa aaattctatc
     3601 actagtatat cacggtgcca gaaattatta ttcaagatat gatacacatt ttttccgcaa
     3661 tgctacggaa atatatattt tgaatagaaa acgcttacaa gatatgcttg gtttataaaa
     3721 ataaaaggag tgattgattt atgaaaaaag cattgattat ttgtgcggca ggaatgtcat
     3781 cctcgatgat ggcctcaaag acaacggatt tctttaagca aaaaagagaa gaggtactcg
     3841 tagatgcagt ttcagctaca gaaggcgata atatgattaa gaatagtgat tttgatttat
     3901 ttctgatcag cccgcaaacg acgatgtttt tggataaatt caaaaaatta ggagaatctg
     3961 ttggaaagcc tgttgttagt atccctttcc aagcgtatgt cccaatccct acaggcatcc
     4021 agaagttagc agaggtgatc gaagagaaca tatgatggaa taggagtgga tgataatgaa
     4081 acagaaggaa aaattgctgt tgagatattt gattgatcac aagaaggagt atgtcaccag
     4141 tcaacgttta gcttctgaat tgttattatc tgatcggaca atccgtaatt acttgcagcg
     4201 gatcaaagag ttagtagaaa aaaacggagg taagatcatt gctaaaccag gttatggcta
     4261 ccaactgcat attttacaaa gactgacatt tgacttgttt ttgagtcggc aagaaatagt
     4321 acctggatat gctagagaac cgcaaggatt ttatgagtcc gaagatcgac aaaagtatat
     4381 attgaaccaa ttgcttttgg aagatgccat tctttttatg gatgatttgg cagaagagct
     4441 ttatatcagt cgttccagtt tgacaaagga catgcaagaa atcaaggagc gattgattcc
     4501 atattcacta aaaatcgttt ctaagcatgg tcaagggaca tggatcgaag gggaagaaag
     4561 aaatcgacgg cattttatca tggatacttt ttttggaaac cattatggaa attcattgaa
     4621 agaatattta gggcaaagcc gttttttccc agacatcagt tttgaagagc tagtcattat
     4681 cattctcgat gaaacaagag aagctaagtt aaaagtttcg gattttatca tacagaatct
     4741 gactttacac ttggctttgg ggatcaaacg gctccgagaa gggtttgaaa tcaaggaatt
     4801 aggcatcgaa caagaagttt ctaagcgagt agagtatcaa gtggcgcagc ggatcgttca
     4861 acgtattgag gtaatcgcag gtgtatcgtt tcccgaagaa gaaattgctt atttgacatt
     4921 acatctcatg gctaagtcga atcacaaaga aaatcaaaat gatcaggaac tatcaaagga
     4981 attagcgaaa gttctgaaaa gattgtctca ggaatttcat ttttcattag tagaggatct
     5041 ccagcttttc aatggactac tcgatcattt gtcaccgatg atgattcgat tgagccgagg
     5101 tattcgcatt gagaacccat tgactgagga gataaagaaa gaaaatccca aagtctttga
     5161 cgcagtaaaa aggcatttca gcaacatgcc ggctttgaaa aactatacca tcaatgaaga
     5221 tgaatgggcc tatttggctt tgcatctcat ggcggcattg gaaaaagaaa gagctgcgca
     5281 taaactacat gcattgatta tctgtgcaac gggttacggc agtgcccaac tattaaagaa
     5341 tcgcgtagtc agtgaattcg gtaaaaatat tacagtggta agtgtaaaag gctattatga
     5401 gatcaatgaa acaactttaa aaggaatcga cctgattatt tcttctattg atctttcgac
     5461 aatgtttttc aaaattccag ttttacatgt cagtattttt ttgaatgaag atgatgttcg
     5521 taaaatacga aaggtagttg gagaatctat accctatcat tcctcagata gaccgatacc
     5581 agcattttct ctacagcaaa aaaagcagat ttacaccgaa cagttgtctg aaaaattttt
     5641 caagacttat acgtacgaac cgaaaaagga agaaattctt catgatttgc tgcaaaagct
     5701 gagcataaat gaagaagaag gatatataag agaaatgcga aagcagatcc agcaacgtga
     5761 aaatatggga caaatcatat tcagtgatac agtggcagtc ccacatcccg ctgttccagt
     5821 tggaatcgaa acaaaggtag ccgttgcatt gattccttct gggatgcagt gggatcaata
     5881 tcaagaaatt cattttgttt ttttagtttc gccttcttat gtcgaaaatg aaggaattac
     5941 ggtcgtgact aaagcaatcg ttaggttagt tgaccagcta aaagtacagc aggaaatctt
     6001 agctgaacct atttttgaga atttcagcag taaatttatc aaactgatcg aataaggagg
     6061 aaaacagatg gctgaaaaaa taaacagtga aacactacaa gtgacttctt ttgatatcat
     6121 tttccatagc ggaaatgcac ggacactgat acatgaagca tttcgctcga tgcgtaaaga
     6181 gatgtttgaa gaagtagaag agaagttgcg acaagcaaat gaagagattc ttcatgcgca
     6241 tcagtcacaa actcaacttc tgaaagaata tgccagcggg acaaaaatag aaatggaaat
     6301 tatcatggtc catgcacaag atcatctgat gacgacgatg acattattgg aagttgcaca
     6361 ggaaatgaat tatttgtatc aaaaaaataa atagaaagga aggatcattg tgcaggatac
     6421 agtaaaaagg aaaatcgaat tagaaaaaaa gcaacttagt ttgaaaaaca tgtatttcaa
     6481 tcgttatcta atcgtacgtt acctgactgc ctttttcttt ttcatgaaca tgcaatggat
     6541 gattctgctt ctatcagcta aaagtttagg aagtagttta ccgatgattc tgattttagc
     6601 tattttgcct gcagtaggag aacaagtaaa gctttatcga aaacaccaaa cgaacgttcc
     6661 atggacaaag tggtattttt tgttccagag tgtctttaat ttattagtga ttccagtgtt
     6721 gtttacctca ggatttacat tcttgtatcc ttttatggca aataacaatg gaggacagtt
     6781 atttgttttc attcttgttg taagcggtat ttttgccagt gcatttatac agtatcgttt
     6841 aaagaaaatt tcactcaacc aagaccaaca gtatatccgt attaaacaat atgaaaaagc
     6901 gttatattta ggaaaggaga ataactaatg tttgattttt tgcagaaata cctgatggga
     6961 cctatgggga aaattgcgca acttaaaatc gttcgggctg tcatggcagc ggggatggct
     7021 tctattcctt tcacgattgt aggctcgatg tttttggttt taaatatttt gccattaccg
     7081 ttcccatttt tagaaggatt ttttaatgca acttttttca aagttagtga cttgtacatg
     7141 atcgtcaata caatgacgat ggggatttta tctatttact ttgccattgt gtttgcttat
     7201 gaattaacgt caattgaacg agatgaacaa aaattaaatg ttaatccgct cacgggggca
     7261 ttactatctg tttttgcatt ctttatgtgt atccctgaat tgatcatgac tgatggtaaa
     7321 atcagcttga ttgcttctat caatgagaca gaaactgtag taaatggtat taggatgggc
     7381 tcttttgtcg aacgtttagg aacttcagga atctttacag ctattattat gtcgattatt
     7441 gcggtcgaat tgtattgtat gtgtgtcaag agaaattggg tcataaaaat gccagatgtt
     7501 gttccgccag gagtttctcg ttctttcact gctctgatcc caacatttgt cattgcgttt
     7561 gtggtgatga tcatcaatgg attattagtt gcactaggaa cggatatctt caaaatgatt
     7621 gctatcccat ttgggtttgt tacgcagttg acgaatacat ggcttggtgt catggtgatt
     7681 tatttcttga tccatgcatt gtggatcgta gggatccatg gagcgaatat catcacttct
     7741 ttcttgaccc cgatcgtatt agctaatatg gcagctaacg cacaaggcgc aaattatccg
     7801 ttggcaggag aattcaacaa ttcttatgta accgttggtg gatcaggtgc gactttagga
     7861 ttgatcatct ttattgcatt cctcgcgaaa tctgatcagc tgaaagtgtt aggaaaagcc
     7921 tcacttgtac caggattatt caatatcaat gaaccaatca ttttcgggat gccaatcgtc
     7981 tacaatccct atttagcggt tccgtttttc ttagctccga tggcttctgc tacactcgct
     8041 tattttgcca ttcggctgga aatcgtcaaa ccgatgcttg cacagatgcc gtggccttca
     8101 ccagtcggga tcggagcatt tgttggtagt ggtggtgatt ggaaagctgc tgtgttagca
     8161 gtcatttgtg caatcatcgc attcattatc tggttcccat ttatcaaatt ctatgataat
     8221 aaattattaa atgaagaaag agaaaaggca gcagaattag ctagtgaaaa gttaaaatga
     8281 tttctaagaa aaaaggaact gtgacaaaaa atcacagtcc ctttttttct tagaaatggg
     8341 aaaccactag tatataaata ccattattct tcaatcaacc gcttcacgat tgcataatcc
     8401 ccttcataag gttcatctac accattgatt ttttgatagg gatccacgcc ttttcccgca
     8461 ataacgactg aatcttgcgg agcgctttct gctaaagcgc gtcgaatcgc ttcaggacga
     8521 tccatttcat aatgaacgat caaatctgga ttagtaattg cttcattgat ttcttccgcg
     8581 atttttttcg gatcttcaaa tgctgggtca tctgccgtca aaaaggcgat gtcagctgtt
     8641 tctgatagca cttttccaaa atcatgtcga cgggagattg ctttgtttcc tgggctgcct
     8701 aatacaacaa ttacacggcc atctggatgt tcatttttgg caaatttcag caatgttttc
     8761 aagcttagat aattatgtgc atagtccaca tagacatgcg ctccattgga ttggatcaat
     8821 tgatccattc ggcctggtac acgagcttct tttaatccgt cttgtgcatc ttgactggag
     8881 gcacctgtta gtgctgcggc aatgatcgca ctggctgcat tttcttggtt gaatcctcca
     8941 gccagcaaaa tatcataagc agtatcgcag atagctaagc gatcttcatg agaagataaa
     9001 gtaaaaccgt gagtaccttt atctgaacgg atcacttgat aattgctttc ttccgaacga
     9061 ccataagtga tcgttggaat ctggaataga tcggctgttt ccctaagtaa atcaaaatag
     9121 tcactttcat gatttaaaac aactgttttt gaattcaaga tcaattgtcg cttgcaatag
     9181 aaatagtcat caaatgtcgg atgttcgatc ggactgatat ggtcaggcga gatattcaag
     9241 aagattccga catctaaagt caagccgtat acgcgttgtg ttttgtaagc ttgtgaagaa
     9301 acttccatca ctagatgagt cataccattt tcaactgctt ctgacatcat acgatataaa
     9361 tctaatgact caggcgttgt caaatgggat ttgaaatatg ttttgccatc taacgttgta
     9421 ttcatagtag aaagcaatgc tgttttttta tttgttgtgt gatccaagat tgcttttgta
     9481 aagtacgcag cagttgtttt accttttgtt ccagtgaatc cgatcacttt caatttattt
     9541 tgcggatagt cgtaaaaagc catagcaaga agcgccattg ctttacggat atccgttacg
     9601 atgattccta ctgctgaatt ttcgtatggt tgttctgata cataatattg aataccctgt
     9661 tcgattgctg aatccaaata ttcttctttg aaattcattc ctttacagaa aaacaaagta
     9721 gaagcatcag cttttcttga atcataactt aactgaagaa attcagcttt ttctggtaca
     9781 tcaagatgcc agcctcttgt tgaaacaaat tcttttaata gattttcttt taatagtaaa
     9841 tgacggatgt cttctaaaga gaagctcatt gattgatccc tcgctttatt caatttcttg
     9901 gtttattata gcacactctt tttaatatat cgtttgtttc cgctatgaca aaatccagct
     9961 ttattcaaat tttcttgaca caggggacaa gcggatgagt attttcataa acaatgaact
    10021 gactgtaata gataggagaa cgaatagtgt ctccaacaat ccaaaaacat aataattcaa
    10081 aaagacgata agactattgg taagtaaaag tccttgcggc attggaagcc gaaaaaattt
    10141 gtggaaaata atcggcggta tcgttatacc gccatttgag gccccgactg tgtacaatgt
    10201 gtaaacccca agactgaaca aaagacttcc tgaaatcagt gaaaagaaat gtgaggagat
    10261 catttccact tttggaacaa tctctaaaac aacaggaaaa agcagacttc ccgctacagt
    10321 cttaaaaaat actgattttc ctaataggac agcggctaga agcagcatca taagattgat
    10381 gctccaaaca gtaactgagc gttggataga aaaggccgtt tcaactaaat gtccgatggc
    10441 gcccactccg gcggaagcta tatcgtgagg gagcaagaac caattcaatc caactgtgat
    10501 aaagaaaaga cctaaaaata taacgggtag tttttttatt tcttgtgtca ttgatatctc
    10561 ctataaatgt tagccataaa aggctgtata tttctttact ttaccaaaaa aacgaaaccg
    10621 aattcaaaaa aacaattgtt cttataaaag ttatataaaa tcgattgcca gtttctgttt
    10681 taccaattaa aatgatagta atgttttgta gaaagttgga atctgaccga tggataatca
    10741 aagaaaacca gcattagatc aattaacacc gcaagaaaaa atggcacgag gctctgcttg
    10801 gatgaccgcc agtaatatca tttcaagatt gctaggcgct gtctatatca ttccctggta
    10861 tgcttggatg ggcgaaaatg ctaaggctgc caatggatta ttcaatatgg gatacaatat
    10921 atatgcattg tttctactga tctctacagc aggaatacct gctgcgattg caaaacaaac
    10981 tgcacgctat aattcattga atgaatatgg cacttcacga cgattattta tccgtgcatt
    11041 acagatgatg ggcgggttag gcctgttgtt tgctttgttc atgtacatcg cctctccttg
    11101 gctagctcat gcttctggtg gcggagaaga actgattcca acgatgcgtt ctttgagtat
    11161 cgctgtattg gtttttcctt gtatgagtgt gatacgaggg tatttgcaag gcaatcaaga
    11221 aatgatgcct tatgcgctgt cgcagattgt agaacaggtg gcacgtattt tttatatgct
    11281 attggctaca ttcatcatca tgaaagtcat ggatggtgac tatgtgacgg cggtcacgca
    11341 atcaactttc gcggcattta tcggtatgct agcaagtatt cttgtccttt tgtatttttt
    11401 gaagaaacat caagcgtata catcggcgtt tattcactac agcgaaaaca aaataaatat
    11461 tgcaacgaag gaattgttgt tagataccgt taaagaagcg attccgttta ttattgtggg
    11521 ttcaggggta acgatcttca aattagtcga tcagttcact tttatgaaga tcatgtctgc
    11581 atccaccgag tattccaatg cacagttact ggatcttttt tcgattttta gtgccaatcc
    11641 agataagttg acgatggtag ttattgcatt ggcaacatcg atcgcgtcta ctgggttacc
    11701 gttgattaca gaagctgtta cgttgaaaga tcgagtaggt ctggcaaaat tgacaagcgg
    11761 aaatttacag ttgttttcat tttttatgtt tccggcgaca tttggtgtta tgttacttgc
    11821 ctatccgcta aatacattat tttatacacc ggattctcta ggaagtaatg tactgatcca
    11881 agcaagtttt gtaggactct tcctaggact atatatgcta gtttccaaca tgctgcaagg
    11941 aatgtttgaa aacaaggcgg caattaatta tttggttatt gggtttctag tgaaactcct
    12001 tcttcaatac ccagccattc gtttatttga agtatacggc cctttattgg cgacaatgat
    12061 cggatttgct gtgtcttgta ccttgatctt aaagagaatc catgaagtag cccgctttaa
    12121 accaagtttt gtctggcgca ggacattgct gatctttatt cttaccttga ttatgctttt
    12181 ggcttcgtgg atcacaaaga tgatttttgg tgctttttta aacgaagata gcaaattcca
    12241 gtctctattg ttgattcttg tagtagcagg tataggggct ttagtgtatg gttatttagc
    12301 tttgaaaatc cgcttggcag aaagactact aggaccagga atagcgcgtt tacgacataa
    12361 attaaaaata aaataagtga atcagaagag ctagattgat gctcttttga aatgggggaa
    12421 acgcatgcgt ttagataagt ttttagcaga tatgggactt ggcagccgca aagaagtcaa
    12481 aggattaatc aaaaaaggaa cgatcgaagt caatggacaa gtggtgaaaa gcgataaagc
    12541 gcaagtaaat gaattcgaag atgcggttac ttatttagga gaaatcatta cgtatcaaaa
    12601 agatttttac tacattttgc ataaacctgc aggagtcatt tctgctactc aggataatca
    12661 tgatcaaacc gtaatcgatt tattggaaga ccaggattat cgggaagatc tttttccagt
    12721 cggccgatta gataaagaca cagagggcct cttgatttta acgaatgacg gggtgtttgc
    12781 ccatcagtta ctatcaccta aaaaacatgt ggagaaagaa tatctagctg aggttagcgg
    12841 tataatgaca gaagaagata tccgtttatt tgcagaagga ctgattattg atggcgatga
    12901 gcagacattg ccggcaaaac tccaaattga tcaagtagat caagagacag aaacttcaat
    12961 tatccgtctg attttgcatg aaggaaagtt tcaccaagtt aagcgaatgg tcaaagcagt
    13021 aggaaaagaa gtcttatatt taaaaagaat ccgtatggga aaattttggc tgcctaaaga
    13081 tttgaataaa gggcaatatc gacccatgac caaagaagag ctagaacaag tgagagaaaa
    13141 ataattgaat ggatagctaa aagaataagc agagtagttg tagcgccatc tgaaaagcag
    13201 acttgtccgt ctgactttcg gatggctttt ttgtgaaatt tcggcttatt tccgtagaag
    13261 ctacttctgg aacaccgttt gttcggaata agggactgtg acaagacttt tgttacagtc
    13321 cccattgttc cttgtgactc agagttagat agtaaggaca cgatctccct aatactcagg
    13381 ccaaaacgct gaattcacaa cctctgataa acggtgttca atcagctgac cctcggtatt
    13441 agctcaaaaa acggcaaaat atgaggaact attttcccgt ttttttctct aatactcagg
    13501 ccaaaacgct gatttcacaa cctctcctat actttgtttc attttcccta tactttgttt
    13561 atttattctc attattgaaa gcgctataat tacgttgcga atgaatcgaa aggggttttt
    13621 agatgaaaaa acgaaagggg ttcaatcatt tttttatgaa tctatggcgt tataaagcac
    13681 ttgtcctgat ggctgtaccg ggtatgcttt ggatgatttt tttcttttac atacctgtaa
    13741 tggcgaatgt cgtagcattc aaaaattttc atatttcagc agatgggttc ttggctagct
    13801 tgagggaaag tccttgggtg ggttgggaaa atttcaaatt tttattttct tcggatcaag
    13861 catttctcat cactaaaaat acaattttat ataatgtagc atttatcctt ttgaatctgc
    13921 tgatctcagt cgtatttgca atcattatga gcgagttgag aaataaacga ctcgttaaag
    13981 tttatcaaac gatgtcctta ctaccttatt ttctatcttg ggtcattatc agttactttg
    14041 tttacgcttt tttaagtcct gacaaaggaa tattcaatca gtggatcact ggacatggag
    14101 gagaagctgt caattggtat aatgaaccga aatattggcc gtttatcttg gtgttcattg
    14161 gtacatggaa agggattggt tataacagca ttatttactt tgcatctgtt atgggaatcg
    14221 atccgactta ttatgaagct gctatggttg atggagctag caaatggcag cagatcaaac
    14281 atgtgacgat accacaactt attccactaa tgacgatttt aacgatttta gccgtaggaa
    14341 acattttccg agctgatttt ggcctgtttt ataacattcc taggaattcc ggtgcattat
    14401 atgatgtgac tcaagttttg gatacgtata tctacaatgg cctgacatcc acaggagatt
    14461 ttggtatgac ggctgctgca ggactttacc aatcagttgt cggctttgtc ttgttgatga
    14521 tcacaaatac gatcgcccga cgttttgata gcgattctgc attattctaa ggaggaaaaa
    14581 aatgaaaaaa aagaaagtgg agagagtcca agtccgctct ttcaataaga cggctaattt
    14641 tttctctaat ataatgattg cactctttgc tatttcctgt attttgccat ttatatttgt
    14701 tatcgccatc tcttttaccg atgagtccat attgtcgact cacgggtaca gtttttggcc
    14761 agaaaagttc agtatatttg gttatacgta cttgttcgac cagatgcagg ataaaatttt
    14821 ccaagcgctt ttcgtcactg tacttgttac tgttttaggt acactgatca atagcacggc
    14881 tacttcttta tatgcttatg cgatttcacg gtcaaacttt ccattccgtc gtttttttac
    14941 cgttttttgt ttgattacga tgttgttctc accagggatg gtggccaatt atcttgttat
    15001 gacaaatctt cttcagttaa aagatacgat ttgggcattg atcttgccaa tggctgtcag
    15061 tcccttcaat attattgtga tgcgcacatt ctttaaacgt tcggtctctg attcgattat
    15121 tgaatcggca cggatcgatg gagctagcga actgcgaata tttgttcaga tcgttttacc
    15181 gttagctgtt ccaggtattg cgacaatcag tttatttgcc gcattgggtt actggaatga
    15241 ctggttcaat gctttactat acatccaaga tgataagcta gttccactac agtatctttt
    15301 gatgaaaatc caaagtaata ttcaatatct gacacaaaat tcaggagcag gaagccaatt
    15361 gacaggcgga ttagcctcag ttccaggaga atctgccaga atggcgatcg tagtcatctc
    15421 gacgttgcct attgcgatca gctatccatt tttccagaag cattttgtca aaggtctaac
    15481 aatcggcgga gtaaaagaat aaagaaacaa aaatataaat cataaaatta ggaggaagaa
    15541 aaatgaagtt atggaagaaa ctagccttta caggtgtttc agcgttgttg ttgggaacat
    15601 tagcagcatg cggaggttct ggttctaaag accaggcaga agctagcaat tcggacactt
    15661 tgcagatgta tcaaatcgga gataaaccag ataatttcga tcaattgatg gaagtagcaa
    15721 acaaacgaat cgaaaaagag atcggtgtaa aagtcaatat caattacatt ggctggggcg
    15781 attacgaaaa gaaaatgaac gtcatcattt cttccgggga aaattatgat atcgcctttg
    15841 cgaacaacta tgtttccaat gcccaaaaag gagcctttgc tgatttgact gaattagcgc
    15901 ctaagtacgc tgaaaaagct tataatgatt tagatgaagc atatattaaa ggaaatctgg
    15961 tcaatggaaa attatatgct ttcccagtca atggaaatgt ctttgctcaa caagtactta
    16021 cttttaacaa agctttacta gataaatacg atctttcaat tgatggaatc caatcttacg
    16081 ctgatgcaga aaaagtcttg aaggaattcc atgaaaaaga accaaacacg gcagcttttg
    16141 ccattggaca aggcttcaaa gtccaaggga actttgatta tcctttaggg aatacgttac
    16201 catttgctat tgatctggat ggagatgatt cgaaaatcat caaccaatac gataatgaaa
    16261 cgtatatcgg actgttacgt acaatgcata gctggtacaa acaaggactc attccaagtg
    16321 acgctgcaac gagcaataag gattatccac tagaaggaaa tacttggcta atgcgtggag
    16381 aaacacaagg accgtatgat tatggcgata caattttgac aaatgcagca aaacaagaac
    16441 ttgtctcaaa agcaattact gttccactaa aatctacagc tcaagcacaa atggcaaatt
    16501 ttgtcgtatc aaatacttca aaaaataaag aaaaatcagt agaacttcta gggctgctta
    16561 acagtgatcc agaattattg aatgggcttg tttgggggat cgagggagaa gcatgggaaa
    16621 aagtcgatgg ttcagatgat aaaatcaaat tgctagatgg ttatcagcca aatacacata
    16681 tgtctgcttg gaatacagga aacaacaaga ttctatatac acaagagtct attacggatg
    16741 acatgattgc caaacgtgat caatcgattg ctgatgcaga aacttcaccg attttaggat
    16801 tcagcttcaa cactgacagt gtcaaaacag aattaagtaa tatttctaat gtcatgaatc
    16861 aatatttaga tggattgaat acagggactg ttgatccaga tgaaacatta ccgaaattga
    16921 aagacgcttt ggacaaggct ggctatgata aggtattgaa agaaatgcaa aaacaatatg
    16981 atgagttccg acaagaataa taatgaataa agacaaaggg gttgtgacaa aagacgtgtc
    17041 acaacctctt gttccgaata aacggtgttc aaaagccagt ttctcggtat taagctaaat
    17101 atatgtaaaa atgtggaaag ccatattcac aaaatttttc ttactactcg aaactaagcg
    17161 gctatttcac aaactcttgg taaacggtgt tcaatcagct aaccctcggt attcgctcac
    17221 aaaacgacaa aatatgagga actatttttc cgtttgtttc tctaataatc aggtcaaggt
    17281 gctgattgcc caaccttttt ttgtataatg agaaagtata aacttaatgt ttggaggaga
    17341 agatatgtta gggaaggttt tggaagagtt atttatccgg atctgggtca ttataaaact
    17401 aaccttgtat ttctggatat atacatttgc cggcgggatc atctttggat taggtgcggc
    17461 atggaaaaca gtcaatgaac tattttattt gtacggattc gagtataaag aaatcacaat
    17521 aaaaagaggc tggaatatat ataaaagaaa ttttttaaga ggcaatctgc tatttagttt
    17581 atttttatct ggtactgctt tattgagtta caatttatat ttatctgttc aaatcaaagg
    17641 gctcattttt ttagctattg attttatttt actttttgcc ttgctctgcc tatttgctac
    17701 ttatcaatac agtatgattt tagatagtga atatacgatc tctgttccta atctgctaaa
    17761 gctaagtttt atttcggttt tttccagctt ttcgtctttt ctaaaaataa ttattggtag
    17821 cggtataatt ttaggcgtga cttggcaatt caaaggattg atcctgtttg gtgtcattgg
    17881 tcttttgacg gtttggaatg gtacgatgac aacacattgg cgtgaagaat tagataaaca
    17941 gttggaaagt tatgaataag tttcggattc tattttcaaa aggaacctta ctaaatcgtc
    18001 tgttgcggaa atacgcggtt atcatgatcg gtgtaacgat gactgctacc gttattttta
    18061 gtatccatac ttgggaacaa aatcaaaaac aggcagaaaa catgacaagt gatgccgttc
    18121 aaagcacaag cagaatgctg aatgataaaa caaccttgag taggatcatc aaaaaccagc
    18181 ttgtagggaa ttccgaaaag atcgaaaatg tgacgaccta cttaacaaaa cccatagatc
    18241 agtatctgat gtatgtatac gaacagcaaa acagtaccga tgaattagtt tctttcccaa
    18301 atcaaatcaa agatctctac gcaaattatg aagaactaag tgcgatatat atcgtgttga
    18361 atcaactacc ggagtattat gaatcttcta gagaaaacaa aggtggggaa ataaaaaagg
    18421 ggacaccaaa attactagac gccttttata tcaagttgcc tatcacacaa ggaggagctg
    18481 agtcaggaag tatttttatt ggttttcaaa agaaagaact agatatgatt ttagaaaatc
    18541 taacgtcatt caatggactc tctttataca tgatttctgg aacgacaaat cgactataca
    18601 cattccatga taataaaata gctaaagaaa cgtttgaaag acaagaaatg atcatcacag
    18661 agagtctgaa gaaaaattca caattgccga ttgacgatct ggaaaaaaac aattttgttc
    18721 aacaccaaga actgtctgat gattatcgta tattagctgt actagataaa aaaagtgtaa
    18781 aaatcgaaac gggaaaaaat cttgccccgc tgatcattgg tatcattatt ttagacaata
    18841 tactgcttat ctttctttat aaaacattca aacgatattc acagcaagta tctatcgtca
    18901 tgcaggccat ggatcaaaca gcagcaggga atttagagac gcggatcgac ataacaaaca
    18961 cggaatatga actgaaggaa ctttcaatcg gtatcaacga aatgttggat agcatcaatc
    19021 agtttgtaga agacatctac aaattagaaa tcaaacagca agacgcacat atgcgggcgc
    19081 ttcaagcaca gatcaatcca cactttttat ataatacatt agaatatatc cgaatgtatg
    19141 caatcagcga aggaagtgaa gaattagcag atgttgtgta tgcgttttcc gctttgcttc
    19201 gaaacaatac gaatcaagag aaaacgatca ctttaaaaga agaactggac ttttgcgaaa
    19261 aatatgtcta tttgtatcaa atgcgttatc ctaatcgagt agcctatcat tttatgatcg
    19321 atcctgattt ggaaaagatc gaagtaccta aatttgtgat ccagccatta gttgaaaatt
    19381 attttaaaca cggtattgat tttactcgat tcgataatgc gctaagtgtc aaagtcttgc
    19441 aggaaggcaa acgggtaagg atcatcatca aagataatgg aaaagggatg actgaaaaac
    19501 ggctaaaaca gattgaagaa aaactgtctc atcctaaagt ggaacttcac ggttctatcg
    19561 gtctgcaaaa cgtgaatgaa cgtttacgtg ccagcttcgg cagcagttat tatatgtcgc
    19621 ttgagaataa tgagacaggt ggactgaccg tttctattac attcaaggag ggatgagcgt
    19681 gtatcaagtg ttattggtag atgatgaata catgattttg aatgggttaa aaaagataat
    19741 tgattggcaa agtttaggct ttcaaatagt agcaacagca gagaatgcca aagaaggact
    19801 agctgtactt gaacagcgac agattgattt agtagtaacg gatgtgacaa tgccagaaat
    19861 aaatggactg gaatttattg aagcggctca aaaagaacgt cataattttg aatttatgat
    19921 tttatcagga taccaagaat tcgattattt gaaaggaggt atgcaattag gcgccgtgaa
    19981 ttatttgatg aaacccgtga ataagttcga attggttgaa agcctcaaga aaatcaaaac
    20041 acggttagat cagcaaaatg aacaaaaaaa tcaacaagaa atctatcaag aactgttatt
    20101 cagtcaatgg ttgaatgaag aattggatga aataagtgaa gaagaaataa taggacaaat
    20161 aagtgagaag cagcatagga tagtattgat tcaactggca agaactcatg atactcttat
    20221 caatagatgg ttgcaagaac ggcaacaaat cttttactat caacgaaatt acggagaccg
    20281 tgtattgatc acgttgttgt tggaggcaga tgaagttgat ggcttctgtt gttttgttca
    20341 agaaaacttt cctgatcagg aatggctgat cagtatcggg gaagagacag attctttgga
    20401 caaaatccct gaaacattcc aacaagcgaa agacaatcta cagttgcatc aattttatgg
    20461 agataaagac gagcatgttt tttacgcagt acaagcagaa acaaaagatc aaaccatcga
    20521 tttttcaagt ttcagacgcg tgctgcaaaa taaacaatta gaagtcgctc aaaaaatgat
    20581 cactgatttt tttgaacagt ttcagttagc agccatgatg ccggaagata tacgatattc
    20641 cagtttttta ctgtttatgg agattcaacg ggaattgatt gatctggaag atgaggaata
    20701 tttacaagga atcgaaaaaa tccatcaggc aaaaacggtg caagaacttc agcagctact
    20761 tctgtcattc atcaaaaagc atcagagaca gaaaaagtac agtgacaatg tggaaaaagt
    20821 aatcgtaatc ctgcaccagc attatcaaga accacttaca ctcaaagaag tgtcagaaaa
    20881 cctgcattta aatgtcatgt atctaggaca gctgttcaaa aaagaaacga aaaaaagttt
    20941 ttcagcttat ttgaaccatt tacgtatgga aaaagcgaaa caactgcttt tgcacagtaa
    21001 tcaaaacatc aatgagatag caagtgagat tggctacaac aacaccacgt atttctctaa
    21061 attattcaag aaaatcgtcg gcagatcccc taaagagtac cgagaaaaca gtggagaatc
    21121 ataaaagaaa aagccaatgt aatgaaataa cttataaaaa attgtctaga aatctaattt
    21181 tgggctgttc ttattacttg aggcaaggca gctttttcat gacctctcga taaacggagt
    21241 tcaaaagcca gtttctcggt attaagccaa atttatgcaa aaatgtggaa agccattttc
    21301 acaaaatttt tcttaatact cgaaactaaa cagctttttc acgacctctc cactaaacgg
    21361 tgttcaatca gctgaccctc ggtattagct caaaaaatgg caaaatatga ggaactattt
    21421 tgccatttgt ctctctaata ctcaggtcag aacgctgatt tcacaacctc tcaataaacg
    21481 gtgttcaaaa gcttgcatct gcggtaataa gaccaaccaa acgaaaaata tgaggatcta
    21541 tttttgcttg gctgttctta ttacttgatg caggacagct ttttcacaac ctcttgttaa
    21601 ttatagtttg ataaggaaaa aggcaaatct tttgcttgat atttcttagg gtgagggatg
    21661 atccctaatt ggtaagagat cgtgccgcct ttcagcaaat cttgatgggt aaaatataat
    21721 ttcgtatatt ctttgtccat ccgtttgatt ttatggataa attgttgctg cggccgatta
    21781 ggcgttgctt caatcgtcaa ttcctttcca tttgacaaaa gcaaaacagc cttgtcaatt
    21841 aatggcatac cgataacata ttcaccggtt ccaggcgtga caggataaaa tcccagacta
    21901 ttgaagatat accaagcggc catacttcca ttgtcctcat ctccagggta acccattgga
    21961 gaatcgtcga aggtctgagt catcaactgt ttaagcagtg gctgtgccat ttcaggttgt
    22021 cctatataac tgaacaagta aggatagtga aaacttggct ggtttgaaat agctaattgt
    22081 ccaaattcta tcgcggccat ctcactcatt tcgtggatct caaaaccata tcctcctggg
    22141 tcaaacgttg ggggctgatt gcacagctca atgagttttt ctttatatct ctcactgcca
    22201 ccatattttc cgatcagtcc tgaaaaatcg tgataaacag caaagctgct ttgccaagca
    22261 cttccttctg cataatcttg tccccaacga ttagctgaaa atggttctct gaacttgcca
    22321 tctttatctt ttgaacgcat aaatcctgac tcatagtcaa agatattttg atagttcaat
    22381 gattgctgct gatatttctt cgtcatttcc tcttcttcta gtaccttggc aacttggcta
    22441 atacaaaaat cgctataagc atagtctaat gtgtgattga ctgattcgtg gtagtgatta
    22501 ggaacatagc catatgtcaa gtaatcttct gttccttggc gtccataatt tggatgtttg
    22561 ctttgaaccg tagcaccttt ttccattgcc gttagaaatt caggcatcaa gtctcgtcgg
    22621 atatctttta cagcagcatc tgcaatgacc gcatcgatca atgtcccagg cataagtcca
    22681 cgttcatcag gagacagcca ttttggcaaa tagccacttt ctctatagct gttcaaaaaa
    22741 ccttccagca tttcttcgta tttttctaca gcaatcaaag aataaagagg ataaaccgtt
    22801 ttatacgtat cccaaaaccc attatttgta tagagaacac caggttttat agatcgacta
    22861 gtcgtatcat agtggatttt ttgcccacta ggatcaattt cataaaatgt ttgtggaaat
    22921 aaaaacaccc gatataaatt atgataaaac gtccgcaatt gttgttgatc atggtgtgtg
    22981 agctgtatac gatcaaaata ggactgccat tgttcttgac tgtgagcaag gtaagtctct
    23041 ttgctttggt tttgttctag ttccaggtta taagctgctt gttccgagct gataaaagat
    23101 gtcccaaatc ggatagtttg tttttttgtc tgttcaaaat acaacgggat cgagtcgcta
    23161 tttttgttgg aaacagctaa ctcatcaatt gttaaaggat attcaaatct caatataaaa
    23221 taaaaagaaa aatcaggatc ttctgaacca gcaaaatgtg tgatttttcc ttccactgtg
    23281 taaggatcta taacaaagag ctgatggcgt cccggaaagg ataaaagtaa accgctgtca
    23341 tttttgctgt aatcaataga taagattccg ccatacatgc taggtatcaa tgtagaacag
    23401 atgccataac gtaattgaca gatcgacaga tgagtcgggc aaaatatact ttcttctggg
    23461 cggtaagaac tttgagcatg gaaaagggtg ttctcctgta gttttccatt gatcggcgta
    23521 aacagcatat gactgaaatc acccatccaa ggacttggtt gatgggtaag acggtagcct
    23581 tgaaaaacgc ggtcatcagg atgaaaccac cagctgccgt tttgatccgt agtttgcggt
    23641 gcaaaataat tcatcccaaa aggaacgcca gtataaggct ggcagttccc attagagaaa
    23701 tttggctgat tcgctgttgc atgtctagta tctatttgac cgatattcat tttatttctc
    23761 ctttgttgat tgtcttttga tgaatgaaac tggaaattta ctatcggatg gtcgatcttt
    23821 tgtctctaac caagtgacca aagcatctcc cgcaagctta cctaactgtt caaaatcttg
    23881 tgcgatggtt gtcagtggcg ggtcaacaag agctgctgct tggatatcat caaatccgat
    23941 aattgaaaaa tcttcaggga tatgataacc atgctgtctc aagagattca tggtctggat
    24001 agcgacaaca tcgttttcac aaacaaaagc agttacttca tacttagtga tataagaaag
    24061 caattcatct aatgtcgcgc ttttgtcatc cagtgaagtg tggaaagtca aaccagcttt
    24121 gtccaatgct tcaaggtaac caaggtaacg ctgtcgaacg gattgtggat gagtctgcgt
    24181 accaaacaaa taagcgattt ttgaatgtcc ctgttcgatc aaataagagg cagcaagcgc
    24241 accgccttgg aaattatcgg aaagaacggt aggaaaaggt aactcataga tttttttatc
    24301 taatatgacg acagggaatt ctttcaatga aagctcaaaa agtaagtcaa gatgttgttc
    24361 tgtatcaaga gcataataaa tcaatccgtc aaattcattg attagctctt ttgctgtttt
    24421 attttgtaga aagtcaagcg tcgtcatcat gacatcaatc tgtttatctt gcatcacagg
    24481 gttcaatccc ttgctaaaat caccaacaga caaatcagcg acatatggaa gaagaaacag
    24541 aatccgtcgt gtttttgtag gagaagcaag aatctgttcc ggagaagcgg atttaacgaa
    24601 actgcctttc ccgcgaacgc gataaataag tcctaattgc tctaattcag tcaatgcacg
    24661 tttggaagtg attctgctta ctttataggt acgtgaaagt tctttttcag ttggtagttg
    24721 gctgtctaca ggtaattcac cagttaaaat agccgtttgc aaatcattaa atattgtctg
    24781 gtacaatggt tgattcatat aaacacctct taatgatata tcatattcaa ataataccat
    24841 aatggatgaa aaagtaaata aaaagatatt ttttgaaagc gtagacataa ttggctgtat
    24901 gaagtataat ctttaaagat atatcaaata gaaagaaggt tttattagtg gcttataaag
    24961 atataccaaa atcggtgcag aaatttatgg aagatatcac acaaaaatgt ggggatatcc
    25021 atgcggactg ggcaaagaat tttacagcag catttgccaa tactctgttg acaacagtca
    25081 aaaagcaaaa tgacggaacc acctttttat tgacgggaga cattccagcg atgtggttaa
    25141 gagactctac tgcacaagtt cgtccttatt tagtgattgc aaaagaagat gaggaattag
    25201 ctgacatgat cagcgggtta gtcaaaaagc aattttttta tatcaatatc gatccatatg
    25261 cgaatgcctt caacgaagaa gctaacggtg ctggccacca aacagatcat acaaaaatga
    25321 acgattggat ctgggaaaga aaatatgaaa ttgattcttt atgctaccca atacagttgg
    25381 cctatcttct ttacaaaaat acaggaaaaa ctgatcaatt caatcaatct tttattgaag
    25441 gtatcaaaaa aatcttggac gtgttcaaaa cagagcaaga tcatgaacac tctccttata
    25501 catttgtacg agacacgaca agaaaagaag atacgctgat caatgacggg cgaggtgcaa
    25561 aaacagcttt tacaggaatg acatggtctg gtttccgtcc tagcgatgat acttgccgtt
    25621 atggatatct ggtaccatcc aatatgtttg cggtggtcgt gttaggttat gtggaagaaa
    25681 tttttcaaac gatactcgat gataaagaaa ttgtacagca aacacagaaa ttgaagaaag
    25741 agatccaaga ggggattcag aatcacggac gaacggttaa tcaaaaaggg caaacgattt
    25801 atgcatatga agtagatgga atgggaaacg ccacagtcat ggatgacagt aatgtgccca
    25861 atctgatcgc cgcaccttac ttgggatatt gttctgaaca agaggaagat tatctgcaaa
    25921 caagaagaac attgttgagt aaagaaaatc catatttcta tgaaggaaag tacgcaaaag
    25981 gaattggatc ctcccatacg ccagaaaaat acgtttggcc gattgcatta gctatggaag
    26041 gaatgacaac gtcagacaaa tctgaaaaag agcggatatt gaatttactt gtagcaactg
    26101 acgcaggaac acaccttatg cacgaaggat tcgatgtgaa caatcctgaa aattatacga
    26161 gagaatggtt ttcttgggca aatatgatgt tttgcgaatt agtcatggat tactttgata
    26221 ttagagtaga aaagtaggag gtatcgtaaa tgaaaaagaa agtatatatc atttctcata
    26281 gccactggga tcgtgaatgg tacatggctt acgaacagca tcacatgcga ctgattgaat
    26341 tgatagacga tctactagag ctatttgaag ttgatccgtc cttcaacagt tttcatttgg
    26401 atgggcaaac gattatttta gatgactatc ttcaagtaag gccagaaaaa agacaggcaa
    26461 tccaacaagc aatcaatgaa ggaaaattga gaattggacc attttatatc ttgcaagatg
    26521 attttcttat cagctcggaa tcgaacgtga gaaatatgct gattggcatg gaagaaagcc
    26581 gtaaatgggg aacccctgtc atgttaggct attttcccga tacatttgga aatatgggac
    26641 agacgcctca attaatgaaa caagctggta tttcagcagc agcgtttggc cgtggtgtaa
    26701 aaccaattgg ctttgataat caagttttgg aagcagaaaa ctattcttcc caatactcag
    26761 agatgtggtg gaaaggacct gatcaaacag caatctttgg tctgctattt gccaattggt
    26821 atagcaacgg gaatgagatt ccagtagaaa aagaagcagc tcttgccttt tggaagcaaa
    26881 aattagcgga tgcagaacaa tatgcctcta cgaaccactt attgatgatg aatggtgttg
    26941 atcatcaacc ggtacaaaaa gatatatcaa aagcaatcca tctcgcaaat gaactgtttc
    27001 cagattacga gtttattcat tctaatttta ctgactatct ggaagcagtt caaaaagatg
    27061 tgccagaaga cttaggctca gtagaaggag aattgacaag tcaagaaacg gatggctggt
    27121 atactttagc caatacagca tctgctcggg tttacttaaa acaatggaat accaaggtcc
    27181 agcgacagct agaaaatatt acagaaccac ttgcgacgat ggcttatgaa gttagtggaa
    27241 actatcccca tgatcaatta gattatgctt ggaagacatt aatgcaaaat catcctcacg
    27301 acagtatttg cggttgttca gtcgattctg tccatcggga aatgatacct cgttttgaaa
    27361 aagcagatga agttggaaag tatcttgcac aagattcctt agaacagctg accgcagcaa
    27421 tcgatacgac cggattccca aaagacagct ttccatttgt cattgtaaat actgcaggaa
    27481 tggataaaac tggtgaagca gaaataacca tcgaattaga aagaaaaaga ttcgctgaag
    27541 gaatacctga acaactatat caagagttag aaaatttgcc taaacgtaag tatcatgtag
    27601 aaacaaaaag tggggccact ataccagcta ttttatctga agaaactgtc caatttggtt
    27661 atgatttgcc gaaagaccgt ttccgtgtgc catatatggc aagaatgatc aaagtgactt
    27721 taccattaga aaacatgcca gcattttctt gggaaacatt cgcgcttgta gaaggggaag
    27781 cgaaagcaga agaaaaggaa acaatgattc atcagagtgg acgaatcatc gaaaacggcc
    27841 ctctacattt gacgattgaa aaaaatggta ccattacaat ggaagatcgc aaaaacaaac
    27901 gaaagttgaa taatctgcat atttttgaag atatcggcga tataggaaat gagtatatct
    27961 ttaaacaacc tttctgtgat cagccaatcc tatccagtaa caaagaaaac tctgaagtaa
    28021 aagtattagt agatacaccg gaaatagcaa aaataagtat tctacaggaa atggaaatcc
    28081 ctgtttctgc agacgagcgt ttagaaaaag aacagcagat ggttgtggaa tttcgttatc
    28141 gaaaagcaga acgatccaaa gaaaaacgaa tccttcaaat aaaaacaatc atgacaatca
    28201 gaaaagatag taaaaaaatc gactttgaaa cgactctcga caatcagatg aaagatcatc
    28261 gcttacgtgt cttgtttcct acaaagttac atgtggaaca tcacgaagca gatagtattt
    28321 ttgaagtggt gaagcgccca aaccatgtgt ctaaaagttg ggaaaacccc acgaatccgc
    28381 aacatcagca agcatttgtc aatattcatg atgaagagta cggtgtaaca gtcggaaact
    28441 ttggtttgaa tgaatatgaa gtaacagaag acggacaaat cgcagtgacg ctacttcgca
    28501 gtgtgggaga actaggcgat tggggatatt ttccaacacc agaagcacag tgtctaggtg
    28561 agcatcggtt caattacagc attgaactac atggaccaga agaaaaattc tctacttatt
    28621 tgcatgcata cgcagcacag attccttttt ccactcaaca aatcaaacat catgaaggaa
    28681 cattgatttc aaaacaacaa tatttaacga taaaaagtga aacgtttgca attacagctt
    28741 tgaaacgcag caagtttagt gataaagtag tagtaagagg tttcaatatg tctagtcatt
    28801 tagaaaaatt ggaaataact aaagacaatg gaaaaactgt catattgaat ctgcttgaag
    28861 aaccaacgaa gcaagcggtt gtcccaataa tccaacctta tgagattcgg acaatcggat
    28921 tcgaggagga aaacgaatgt atggcggaat agaagcaggc ggaacaaaat ttgtgtgtgc
    28981 ggtttcagat ggtggagaaa ttttaga
//
LOCUS       DAZKCH010000031        28504 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000031 DAZKCH010000000
VERSION     DAZKCH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.031"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..243)
                     /locus_tag="ACG84X_001359"
     CDS             complement(<1..243)
                     /locus_tag="ACG84X_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9127245.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
     gene            complement(260..1732)
                     /locus_tag="ACG84X_001360"
     CDS             complement(260..1732)
                     /locus_tag="ACG84X_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFP9127246.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            complement(1746..2594)
                     /locus_tag="ACG84X_001361"
     CDS             complement(1746..2594)
                     /locus_tag="ACG84X_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127247.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            complement(2591..3457)
                     /locus_tag="ACG84X_001362"
     CDS             complement(2591..3457)
                     /locus_tag="ACG84X_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127248.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            complement(3500..4813)
                     /locus_tag="ACG84X_001363"
     CDS             complement(3500..4813)
                     /locus_tag="ACG84X_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFP9127249.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            complement(4953..5924)
                     /locus_tag="ACG84X_001364"
     CDS             complement(4953..5924)
                     /locus_tag="ACG84X_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9127250.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            complement(6062..6277)
                     /locus_tag="ACG84X_001365"
                     /pseudo
     CDS             complement(6062..6277)
                     /locus_tag="ACG84X_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6442..6777)
                     /locus_tag="ACG84X_001366"
                     /pseudo
     CDS             complement(6442..6777)
                     /locus_tag="ACG84X_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387932.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            6959..7564
                     /locus_tag="ACG84X_001367"
     CDS             6959..7564
                     /locus_tag="ACG84X_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9127251.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            complement(8276..8476)
                     /locus_tag="ACG84X_001368"
                     /pseudo
     CDS             complement(8276..8476)
                     /locus_tag="ACG84X_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8683..8835)
                     /locus_tag="ACG84X_001369"
     CDS             complement(8683..8835)
                     /locus_tag="ACG84X_001369"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127252.1"
                     /translation="MFSGDWGIVSYSILTLIAMVLGTSFYNAFVSKHVEEYEVLMYLK
                     EKKTSN"
     gene            complement(8953..9912)
                     /locus_tag="ACG84X_001370"
     CDS             complement(8953..9912)
                     /locus_tag="ACG84X_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9127253.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            10178..10522
                     /locus_tag="ACG84X_001371"
     CDS             10178..10522
                     /locus_tag="ACG84X_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFP9127254.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            10523..10942
                     /locus_tag="ACG84X_001372"
                     /pseudo
     CDS             10523..10942
                     /locus_tag="ACG84X_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(11034..11384)
                     /locus_tag="ACG84X_001373"
     CDS             complement(11034..11384)
                     /locus_tag="ACG84X_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127255.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(11350..12681)
                     /locus_tag="ACG84X_001374"
     CDS             complement(11350..12681)
                     /locus_tag="ACG84X_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFP9127256.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            12937..13503
                     /locus_tag="ACG84X_001375"
     CDS             12937..13503
                     /locus_tag="ACG84X_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9127257.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            13648..13735
                     /locus_tag="ACG84X_001376"
     tRNA            13648..13735
                     /locus_tag="ACG84X_001376"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13680..13682,aa:Ser,seq:cga)
     gene            14069..15043
                     /gene="bsh"
                     /locus_tag="ACG84X_001377"
     CDS             14069..15043
                     /gene="bsh"
                     /locus_tag="ACG84X_001377"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFP9127258.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            15368..17263
                     /gene="asnB"
                     /locus_tag="ACG84X_001378"
     CDS             15368..17263
                     /gene="asnB"
                     /locus_tag="ACG84X_001378"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFP9127259.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(17458..17904)
                     /locus_tag="ACG84X_001379"
     CDS             complement(17458..17904)
                     /locus_tag="ACG84X_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFP9127260.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            18132..18281
                     /gene="rpmG"
                     /locus_tag="ACG84X_001380"
     CDS             18132..18281
                     /gene="rpmG"
                     /locus_tag="ACG84X_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFP9127261.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18369..18887
                     /locus_tag="ACG84X_001381"
     CDS             18369..18887
                     /locus_tag="ACG84X_001381"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFP9127262.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18964..19920)
                     /locus_tag="ACG84X_001382"
     CDS             complement(18964..19920)
                     /locus_tag="ACG84X_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9127263.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            20086..20892
                     /locus_tag="ACG84X_001383"
     CDS             20086..20892
                     /locus_tag="ACG84X_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127264.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            20889..21878
                     /locus_tag="ACG84X_001384"
     CDS             20889..21878
                     /locus_tag="ACG84X_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFP9127265.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            21875..22879
                     /locus_tag="ACG84X_001385"
     CDS             21875..22879
                     /locus_tag="ACG84X_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFP9127266.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            23011..23553
                     /locus_tag="ACG84X_001386"
     CDS             23011..23553
                     /locus_tag="ACG84X_001386"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFP9127267.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            23573..24271
                     /locus_tag="ACG84X_001387"
     CDS             23573..24271
                     /locus_tag="ACG84X_001387"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFP9127268.1"
                     /translation="MNYQQQIKLRVWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            24292..24504
                     /locus_tag="ACG84X_001388"
     CDS             24292..24504
                     /locus_tag="ACG84X_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFP9127269.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            24504..25466
                     /locus_tag="ACG84X_001389"
     CDS             24504..25466
                     /locus_tag="ACG84X_001389"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFP9127270.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            25484..25879
                     /locus_tag="ACG84X_001390"
     CDS             25484..25879
                     /locus_tag="ACG84X_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFP9127271.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            26042..26407
                     /locus_tag="ACG84X_001391"
     CDS             26042..26407
                     /locus_tag="ACG84X_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFP9127272.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            26404..28215
                     /locus_tag="ACG84X_001392"
     CDS             26404..28215
                     /locus_tag="ACG84X_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFP9127273.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTNENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(28277..28444)
                     /locus_tag="ACG84X_001393"
     CDS             complement(28277..28444)
                     /locus_tag="ACG84X_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFP9127274.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
BASE COUNT         9032 a         5154 c         5515 g         8803 t
ORIGIN      
        1 tttcggggtc gaggtaatgt acccataagt ggcggaatcg cgatggatat cgataggccc
       61 aaatgagcca atcccaatcc ctgctaaatc tgcttggtat tgtttgaaga agtcaatgac
      121 taaaggtatt gtttcctcag gtgtcgttgt cggaaagctc actctttcct tgatcgtcat
      181 ttcttcatcg ctaatggcac acacaaattt tgtgccgcct gcttcgattg aaccataaat
      241 catcactgag ctctcccttc tatagattaa ttaagccgct ttccaatgaa aaggttactt
      301 cactgtctgc cagcaaaaga aaatcctgtc ctttttctgt ctcataaaaa gttgtactca
      361 tagtcagacg atcatttaga aaaagctcaa tagctgaagt atcacggaaa atttcgatgg
      421 ttagacaatt attttccaaa ggaatcgtca cactgcgctt tttcaacact tccttttcag
      481 ctcctgataa atcatacggc atgtgttccc tggaagcagt aaagcactcc cgttcaacat
      541 catagttaag cagtaatgta tggtcgggtc ccttcgcata gtgaagttct agtttcgttg
      601 cctgttttaa attgatttcc aagcgtaaat agtgctggtc atatactaag tccttcagta
      661 agaagcgatt ctcttcagtc ttcgcccatt caatcctttc ctgcggatca attacttgat
      721 aaattgatga aactggccgt tgcaacaatt gattatcagc caccctcagc tctctaggca
      781 aggtcatgga acctgaccaa ccatggccca gatcattcgt aggtatttta cgctgccaca
      841 tttgcatcca agcaatcatt attctttggc ctgcttcgtt ttcacaggtc tggggtgcat
      901 aaaaatctaa accgccatcg atttcatgaa aattctctac tagaaatttg cctgtttgcc
      961 aatcgacagt accgatgaaa gcaacagttg agttcgtatt ttggtaagca ttgccttgtg
     1021 gagtcatttg aataggagaa agaatcaaga cttctttgcc atctagttca aacaagtctg
     1081 ggcattccca tacaatgcct tgttctggag ttccctccag caatacggaa taaaactccc
     1141 aagttagtaa atctttggaa tggaacatca caatttgtcc acgagcatct gcagttttag
     1201 tagcgactac agtaaaatag tcttcttttc gctgaaacac tttgggatcg cggaaatctt
     1261 cggtcgttgc aacagaagct aagtgatctt ctgcgatgat tggatttccg gcatattttt
     1321 caaagtgaat gccatcttct gaaactgcca aacactgaac ttgtcgaact tgcccttcca
     1381 caacattgtg tcctgtataa atcaaataca gcttgccatc cttttctatg gcactgccgg
     1441 aaaaacagcc ttccttgtca tagctttcac ctggtgccag tgctactggc aaatgctccc
     1501 agtgaattag atccttgctt ttagcatggc cccaatgcat tggtccccag atgctgtcgt
     1561 aaggataata ttgataaaac aagtgatact cctcttgata ataaacaaaa ccatttggat
     1621 cattcatcca gccaatcgga gccatcaaat gaaatttatt ccggtattct tgattgactg
     1681 tttgagcatt tttctcaata aactcattgg cctttaaaag tttttgcaac attcactatt
     1741 cactcctatt ttatacccgt tccagaaccg ccaagtccct gcagaatata tttttgtgca
     1801 acgatataaa caataatcag tggaatcgtt gcaatggtta aaacagccat cacttgattg
     1861 atataaactg gctgtgtagt attgatcgta gtaattgcca cttgcattga aaatttgctg
     1921 ctgtcagtta agaccattaa cggccaaata taatcattcc agctggagat aaaggataag
     1981 acacctactg tggctatggc tggtttagac attggcagca tgatgtgaaa gaaaatttta
     2041 acaatatttg caccatctaa tttcgctgat tcaatgattt cttctggaat cgcgataaag
     2101 aaatttctaa acagatagat attaaacgcg ctggccatcg ctggtaaaat cactgccaag
     2161 cgagtattca ctaagcctag tgaattaacg atggtaaatt gcggaattaa aaccgtctcc
     2221 atcgggacaa tcagcagagc taacaaagct ccaaagataa ttttcttgcc tgaaaaatta
     2281 accttcgcaa aggcaaaacc cgccaaagag tttacaatga ttgacccaca ggcaaaggtt
     2341 aaaccataaa aaatactgtt taataaataa gttcccacac tgaaccggga aataacctct
     2401 tgataagttt taaaccaatt agctggattc aaactaggta aaaaagcttt gaaggaagct
     2461 aaattttgat agacatctgc ttcaggcttc atagaggaaa ctaccatcca cagcatcggg
     2521 aaaatgaata atgccgctaa aaggaacagc aaacaatatt ctacgatcat tagcggtcca
     2581 aatttcttgg tcatgctgga tcatcctcct ttaccaattt tctttgagca attgtaatta
     2641 aaccaatcat agtggtaaag attaacgcaa tggagctgga gtagcctacc atacggtctg
     2701 taaatccagt ttggtaaatg taataaacca ttgtcatagt agaattcatt ggtccacctt
     2761 gagtcattac cattggctga atgattagtt taaaggccga aatcaatgtg gtaagtaaaa
     2821 taaaaatcgc cgtgggcttt aataatggca tggtgatata gcgaaattgc tgaaacttag
     2881 aaaaaccatc aatttcggct gcctcataaa cgtcttgcgg aatattttgc attcccccta
     2941 aaaacagcag catctgatat cctgcacctt gccatgccga tacgaaaaca agcgtataca
     3001 ttgcttgttt gggactagtc aaaaaaggct gcgaagcaat tccaatcttt gcaaatagcg
     3061 tattaaccag accttcatta ggatttaaca agtacaacca taaaatcgaa ataacgacta
     3121 aggacatcac gactggcgca aaaaaggcta ctttaaaaaa gatatttcct ttacgatttt
     3181 tgttgataat aagtgccatt cctaaagctg cccctatttg gaccggaata atccaaacaa
     3241 caaatttagc cgtgttccaa atacttttta caaaaattgg atcagcgaac agtcgcttaa
     3301 aattttctaa gccgataaat tgtctagcat ctggcgttaa caaataataa tcagtaaagg
     3361 cataataaat taccatgatt acgggtatga tcagaaaaat cgtcagcagc agcaaagctg
     3421 gcgctagaaa gccgtaacct atcaaattgt ctttcattgt cggttttttt aacacttgat
     3481 tggccccctt tagaaacttc tattttagtg aagtatcaat tgcctgttgc atttcagcag
     3541 cgcgactatc tgctactttt tgtacatctg ggttttcctc gaagtagcta atatcttgaa
     3601 ctgcttgttg gaatgctcta gatacttgcg gataagctac aaccactggg cgggcatgtc
     3661 cagaaagttg gttttgctta attaatacct gcattccttc cgacacttca tctttaatta
     3721 aatcaactgt tgaatttctg ataggtagaa cactgttccc taaactcata atacgactag
     3781 attctgtact ggttgcaaac ttaataaagg ccgcagaagc atcctttttc tctgttttct
     3841 cagtcattgc taactgccag cttccggttg gtgaaactaa ctccccagtt gcatctgaaa
     3901 cggggtaagg caaaatacca taatcaatct cttgatagtt ttcctctaaa tctgccattg
     3961 tccaagaacc gctcagcatc atggcatatt tgccagtttc aaatcctttt tcaataggac
     4021 tgattgtggt gtaacctttt tcaaccaatt cttgaataaa ttccaacgct tcaacggatt
     4081 ttttaccgtt aaaatagtct tcggctttgg ttccatcagc attaacgaca tcgccgccat
     4141 tcgaccatat aaatggtgta tatgcgtagg tcagcatttc gtctcccgac gccatttgca
     4201 tatcaattgc aggcgttttg tatttatcag tcagcttttg gcaaattgct tgaaattccg
     4261 tccaagtcca aggatcttct aacgtcggca attgatcttc tgtaattcca gcatctttga
     4321 acagcgactt attgtaatag acacccacac tggactctga gaaaccaaac gcatacattt
     4381 tgccatcgta ggttccttgc tgaataatgc tgtctaatac atcatccatg tccgcatctt
     4441 tcaaataatc atctaatgga gcaatgactc ctgaatgagc ataagctgca gtattcggtc
     4501 catctaacgt aataacatca ggaagggtat tggttgtaat tgcagcattt actttatcct
     4561 catatccacc gccgcttccg ctacgaggaa tatactcagt aacagcttta tattcaccct
     4621 cgtattcatc attaaaattg ttcacaatct ctgcccaagc ttttccttca ggcgtttcat
     4681 cagaaaactg aacccaaatc ttaatttctc ctggatcact gctacctgaa cttttctcct
     4741 tactgccaca tcctgcaagt cctccagctg ttaatgctaa aattgctgca attgctaaca
     4801 ttctcttttt catcgatgtt cctcctattt tttgaaacgt ttccgtttta tttttcaatt
     4861 aattggtaac gtttccaatt aattggtttt aagatatcat tgaaatcact ttctgtcaac
     4921 ctatctcaaa aaaatcgtta taaaccggtt ttttactctt tagtcgtctc tccagcgtga
     4981 aagaaaaccg gtactaccac acgcttaggc ggttcttcat ttaaaatcat cgccatgagt
     5041 gtttctactg aaaccttggc catttcctct atcggctgta caatcgttga tagtaaatag
     5101 tctttttgca acgatagctt gactccatca aaaccaataa tttgaaaatc cttaggtgct
     5161 tccttcccta gttttttttg ggcttttatc acatccaaag ccatgaaatc attgatggta
     5221 aaaatgctat caatttcagg attatccgaa aaaaaagcga gcaattgttc ctctaaattg
     5281 ctaattggtt caggcatatc caataccttc acagctattt tattttcctc acaaatattg
     5341 taaaaaccag ctttacgatt gtttgtttcg ttagggtaag gtgaaacacc cccaacatag
     5401 cacaagtttt tacagttacg agtaagtagt tcttgagcgg caatttgccc acctaaataa
     5461 ttatctgccg ttacataaga aacctgttcc gaaaaatggc ggtctatact gacaaatggt
     5521 aaatttgatg atacatattt atcaatgtct gaataggtaa tacctataat tccgtctact
     5581 ttactctgct tgaccatttg gatatattct ttttcttttt ccgcactgcc gttcgcatta
     5641 cacaaaaaaa gcttataatt tttttggctg agagcttcct ctacatagta ggcaaactcg
     5701 gaaaagaagg gatgccaaat cgtaggtaaa ataagagcta ttgtattgct actattcgtt
     5761 ttcatacctc tggcatattc atcaggctca taattaagct cactaattgc agccattact
     5821 ttttctttgg taacctcttt cacctttact ccatttatta ctctagatac cgtacccaca
     5881 ccaactcctg ctaacgcagc aacatccttc atagtagttt tcacttcacg aacaactcct
     5941 ctcaaaagaa tttcaggtat tattatacca aaagaaggaa acgattccaa attagcagga
     6001 atatttttat tttaaaatag atattagacg tgaagctttt cgtaaaaaaa ttttcgtatt
     6061 cagatttacc ggattgactc tgtcgccaat ataggccggc atactttgtc aattttattt
     6121 catcagaaaa acgttcaatt ggaccaattt cagcgagtat tccagcagcc taaacaggac
     6181 caatacctgg gatactggtt aaacattgat actccggtag caccacgact aagtcgtcaa
     6241 tggctttatc taagtcttta attaattttt caagattggg gtacatggaa catagaaacg
     6301 aaaatgcacg gtagtgaaaa attaaaaaca caagaatcgt tgatttatta gtattcttgt
     6361 gttttcaatt ttatacattc aaaaatagta tctggaacat ccgtgcgaaa atgcacggta
     6421 ggaaccaaaa gacgaacatt ctcaataatt ctctatattt aacggacgta gtattccatt
     6481 cgataattct ttttcatagc ggaaactata tttgccaaca aaattaatgt gatcactaat
     6541 taatggaaat tgcttgcgta acacttcttc ggaacagtcg aacccttccg ttttaatttg
     6601 ttcaaagact ttttctaaat atagtgaatt ccaatatatg atagcattag ttactaatcc
     6661 taatgcgttg agctgttcct ccataccgtc gtaataagtt tgataaagtt tgccttttct
     6721 accataaaat atatttcgac atagagcatg acgagcttca cctttattta actgttccga
     6781 gctaggctct cctaaataaa caccaaaaga atttttattg cgcttaattt cattcattca
     6841 aaacctccaa agtaaattat aagtagactt aaaatttatt tttaaaaatg ctatgataac
     6901 agtaaaacta caagtaaatt ttacatgtaa attatatcat tttttaaaag gagtttttat
     6961 ggcaaaaatt ggatatatta gagtgtcttc acaagatcaa aatttagatc gacaattggc
     7021 aatgatggaa gaccttaaca ttgataaatt attccaagaa aaagccagtg gtaaagatat
     7081 ccagcgacct gagtttcaaa aattactaaa ttatatccga gaaggtgatt gtgtcattgt
     7141 tgcatcactg gatcgcctag gcagagatta tgaagacata aaaaatacag ttacctttat
     7201 gaaacagaaa aaagtagcat taaaaatact agatgcacag tttttagatt ttaatactgg
     7261 aaatgaactc ctagatactg ctatgttcga tatgttttta tcattgctaa gttatattgc
     7321 acaaaacgaa cgtgagaaaa tccgtgaacg tcagcggcaa ggagtattat tggccaaaaa
     7381 agctggtcga tataaggggc gaccaattga atattctgag aactcaacag atccgcaaaa
     7441 acgattagtc tttaaaactg tggtggacat gttaaatcaa ggagttccag ttgcagaaat
     7501 tgccaaagaa aatggtctct ctcgaccaac catatataaa ataaagaaag cgaatgattt
     7561 gtagaattta tactatattc attcgctttt ctaccgtgca ttttcgtttc tatgttccat
     7621 gtaccccata ttctctatga aggagtttca atgtcatatt ctttttcatt agttctttat
     7681 gaacatattc ccagtctaca ggaaggtaac ctcgtgctgt tgtttgtttt tccggaaaaa
     7741 gatattccta cagccaagta tcgctcatat cagcggttag ttcagtcacc cccttcctgt
     7801 ctgctcgaga agtaacttct cgaatcgtat gtctggagct tcccacagtt aaactaatcg
     7861 ttcgttgaga aataccggaa aaataaagct ccaaaatttt tcgatagtga accaataaaa
     7921 taacattctg tataagttgt cataccgaaa ggtatgcctt tctattatac agaaggttat
     7981 tcatctatta aatatgaaag tggagcagtt tgttgccctg gatggagcta tctattgcct
     8041 tgagtggagc agttattcac ctcactggag ctatttatct gcaatactca acttgtttaa
     8101 attttttttc agtaactaat aggagtcaat ggcaatacgt acatccatgt attctaaagt
     8161 ggtacaaaca aggggattat ccatcggttt tctttcaaac gagcttagag ttgccctgag
     8221 ccaactaata aatagcaaaa caagcgaacc gagagaaggc ttcgcttgtt tctgatcaat
     8281 tctgtttaat tttatctagg atcacttcaa atgtttcaaa ggtatctata tctaactggc
     8341 acagccaaag taagtatttc ttttccttat atgtctagtc aacagtgggg taggaggtga
     8401 tcaaattatt gtatcttgct ctttgttcac ttgatgctag ctgccagcgt ttctcaaata
     8461 ttttttcttc ttccattatc gatcccccaa aaagagcgct gcctgaaact tcaataacgg
     8521 gcagcgcaag tctaattatg cagatctatg tatagcataa caaacaaata tgaaaaaact
     8581 tagaaggtag tagaagttct ggcgtctttt gctttgcttt cgttcttaat gtgtttcatt
     8641 ctagaatatc tcaaaataaa aactatgcgt ggtgttctca tattaattac ttgttttttt
     8701 ctcttttaag tacattaata cttcatattc ctcaacatgc ttacttacaa aagcattata
     8761 aaatgaagta cctaaaacca tagcaatcaa tgttaatata gaatagctga caatacccca
     8821 gtctccagaa aacatttcag gaaacactgc ttgtggaaga cctagtatta gaaatgaaat
     8881 ataacagatc ataactacat ttaataagtt tttattccta tctgtcactt ttctttttaa
     8941 atgtcttaat tgtcaaatta agttagacag atcatcaata cttacgtaac tcaaaaatac
     9001 ttccaaaggt gttcgataat ccagtgattt tctaggaata ttatttcgtt tagatgcgac
     9061 agattgaata aaaaattcat ctactgaatt gaaatccata gatttcaata aaccatctct
     9121 acgtaacaat ccgttagaat tctcgtttag gcctctttga gacggcgttc ctggatcagc
     9181 gaaataaatg gcaatatcat tgacattact gatctgtttc caatttgaaa attcctttcc
     9241 acaatcaaaa gtgatggatt tgaataggtt tttcggtaca gattcaaacc attgatttaa
     9301 ttttttttca atatcaatcg cttgtctacc acacggtttc aatgtgatga taacttttga
     9361 taatcgttca actaaggtaa ttacagcact tttatgtttc agacctacga tagtgtcacc
     9421 ttcaaggtga ccaaactcat ttgagaattg gctataatcc ttttcacgtt catgaataga
     9481 gcggcggaaa gtttgttttc cacgtctttc ttgatgtcca ttcggtttac gcttgccttt
     9541 catcggtaag tcagaagaat caaatagccc ctttttgaac atacgataaa tggtacgagc
     9601 agaacaacta ataggaaacg ctgcacgacc aacaatcaca tcgggtgtcc atccttgaac
     9661 aacctttctt tgaatatatt ctgattgttc ctcgggtaaa acaagcggac gtctaccaca
     9721 gtttgatttg tttttcttat actgttgata atattctaag gctgattttc cttgcttgaa
     9781 gaacagatat actttatgga tcgtttgtct tgaacgattc aagcaatggg cagttttagc
     9841 aacagattga ttcattttga aataagactc tattattaca agttcatccg ttgtaagatg
     9901 ggtataggtc atttgtactc actccttata attctttggt cggaactatt ttgagtgtag
     9961 cacaaatgac ttttttagtt gtctagctta attttacaat cggcgaataa aaaaagcgtt
    10021 agcaactatg cttaaaaagc atatcgactg aataaactaa gcattggaca ggctgaaaga
    10081 ctacatttaa aatgaaatgc gaagaaacaa tagaaaataa agttgcctta gaaccatagt
    10141 tgaatcacct aacagtcgtg aagggagaat aagagaaatg gcagaaaaac aaaccgcagg
    10201 acgagatcaa ttaggagatt ttgcaccaaa atttgcagaa ttgaatgatg atgttttatt
    10261 tggacaagta tggtccagag aagaattatc tgctcatcag cgtagtatca tcaccatatc
    10321 tgcattaatt tcaggaggaa attttgaaca attgccagct catctgaaga ttggcaagca
    10381 aaatggcatt actagtgaag aaatagcaga aatcattacc catttagctt tttatgtagg
    10441 atggccaaaa gcttggtcag cttttagttt agcaaaagaa atctatttag aagaaaatag
    10501 cgaagataag aaagaggcgt aaatgacgac aaaacacgaa gaaatacaca atggcgtgat
    10561 ttttccagca ggtgaaaaaa acgaagctta cgctcaagta tttaccgggt aaagctatct
    10621 gaatatgtta gtgaatgatc ccgaagtttc tgttggtgta ggtaatgtaa cttttgaacc
    10681 aggttgtcgc aatcactggc atgtccataa agacggctat caaatcttac ttgtgaccgg
    10741 aggagaaggc tggtatcagg aagaaggaaa gccagcaaga cgattaatgg ctggagatgt
    10801 cgtcgtaacg cacaaaggga ttaaacattg gcatggtgcg acaaaagaca gttggtttga
    10861 acatttggcg atcactgctg gtaattcaga gtttttagaa cctgtaacag atgaagtgta
    10921 tgaaggattg gaaaatcaat aatgtcaagc ttgaacagct cctgaaagta gattttaatc
    10981 gaactttcag gagctgcttt tttgattcag tcttttataa atagaaaata gggttaataa
    11041 taggaatgag aagcacgtcg aaagatctta atattgataa tcggctgggc atacatgatt
    11101 tccacgtcat caatcaaact acctaacaga tgataatctt cccgatcatg tcggggatta
    11161 cctaatagtt cttgataata gatttccata ctagggtccc gaggattgtt cagcaaatca
    11221 gcaagtacat ctaaatcttc tggctgagtt tctgccgtac cctgtatctc tatgaaaagc
    11281 ccttcctcag caaattctac tccaatacgt atttcagtta tttcatggga atataaataa
    11341 gtaagaagct catcgatgat tctttttgat aattcttttt ccaagtgtct ttttttcctt
    11401 tctgacagcg gtaaagttat ctagtatcgg tacaaggata cctgcaacga aaccagttga
    11461 aaaaccactg ttatatagat ttagtcctcc gtgcaaagtg ctgacgttat ggacaagagc
    11521 aatatgtagt acaccagcta ttacaccgta aaaactgccg taaaaaccgc ttatgggcgc
    11581 gagacctgtc ccaaacacag ctgcaacaag catgccagta ctggtgatct catgaaaagt
    11641 tccaaacaaa gaagcaataa atattccgac tagtatcgga aaactgtttt ttaaatgaca
    11701 accaaaagca ctgaaaccca ccgcagataa aatagcaccg atgacaggtc catttaactg
    11761 accgccaacc agcaaaacat aagaagacag catcagacca actaagccta tgttgatcaa
    11821 agtagcacca ataccagaat tagcaatgaa atcagttgtc aattttccag atgaatcgaa
    11881 aatttctcga atccccaaaa gccgaaagga attataatag aaaccaattc cgactgtcag
    11941 cgaaaaaaag ccaaaaataa tccaaatgag aggaaagtga tattcattga aaaccaatgt
    12001 attttcgacg attgaatagc tgaataacct caaaacagca gtaaaagtca tcgcaatcaa
    12061 cccagaggtg aatccaatat tataaagtgt gaatccacga tggaaaacta aagtttgagc
    12121 agctaagggc ggaagaagta gaccaattgc tatgccagct aaattcccca ataaaatacc
    12181 tatcagtaaa ggaaaacgca taccaaaagt gatataacta acgaccggtg ataatgcgct
    12241 accaaacagt ccgatcatga tgtactgaga aaaaggttta ttgacaaata cagcgtatag
    12301 atacacacct aaaatgattg agatagaatt ataaaggttt ttgccaaaaa aagagaaacc
    12361 ggtaactgtt agaatcgaag caaataaggg accgtttaaa atcaccttgt gccgataagc
    12421 taaaagcaca gaaagtaagg tcaaaatccc tacatttatg aatgcgcttc cgaaaccgcc
    12481 taaagcaaaa taatctgtca aaagattgct tggcgaggta agaatagtta gcaatccact
    12541 ccaattatca gtaggagtat tagaaagcaa gccaataaaa agaaaaaaaa cacctgtaaa
    12601 accaagataa aaatactttc ttttctgtga aacgattcgt ttttgaggat gaatataaat
    12661 aacgtcagtt tcgttttcca ttacacacct tctttttcat tttctttaac tataacttga
    12721 aatgaaagat ttggacaact atcatttagg tcaaaactaa aaatgtaagg gaacccattg
    12781 aatttaacca aattttttta attttgcaaa aaaaagttaa agaagactga aaaaaaattt
    12841 aaaatataac gttttgagta aaatgtttgc aaaaaatgct aaaaataggg tacaataaaa
    12901 caacatatac tgcagtaaag aagtggggga gttttaatga gaagaaaagt ctataccaag
    12961 gatcaaattc taaaagctgc ttatgatgtt gttgcaaagg aagggtttaa aggatttact
    13021 gcgagaaata ttgctaaaaa gatggggatt tcgacacagc cgatttatct ggaattcaaa
    13081 aacatggaag atttaaaaaa tacgttgctg gattctatct ttgaacaact aaaagaagat
    13141 gttttcccta ttgaacgtac tggtgataaa atcattgatc tcggtttgaa ctatatctac
    13201 tttgcaaaaa agcatcatag tctttacatg gcattgtaca ttgatgaaca tggggacgga
    13261 aagaaaatgc atgatttttc atacaattat ttccgtgaaa tagttaaaga agatgaaaga
    13321 tacaatcaat tatcggatga atatgtcgat gctctgcata ctggtacatg ggtagcagtg
    13381 actggcttag cgtcattgat gtcatcaaac atcatgcatc caacagaaga acaaatcatt
    13441 gcactgatca aacggacaat tgactcgatt ttagcattag ataatcctga aataatcaga
    13501 tagtgttcta tcagtatgaa tttgatcggt aagtccgttg gctgcaaact gtcaatggac
    13561 ttttttgcta aaaaaagcga tttctgttat ttatctatta gaaataggct tgacatttcg
    13621 tgaaaaaagt ttaaaaatag tacttacgga aggttggcag agtggtaatg caccggactc
    13681 gaaatccggc gaaccggcta ataccggcgc gcaggttcaa atcctgtacc ttccttatat
    13741 caaagattag aggttgtgaa gaagctgtcc tgcatcaagt aataagaacg gccaaacaaa
    13801 aatagctttt cctatttttt cgtttgattg ggcttattac cgcagatgca agcttttgaa
    13861 caccgtttgt tcggaataag gggctgtgac aagacttttg tcacagcccc ttattgttgt
    13921 acttttaacc tacaatattt tttgattccc cctgagtact attttttata aatgctagta
    13981 aatcaatctt ctttggcctt tttttgataa aaaaaatact agatgtaaga taaaagtgta
    14041 aaaacgattt gttttaggag gggaaacgat gtgtaccgca atcacttatg caacgaaaga
    14101 ccattatttt ggaaggaatt ttgattatga gatgtcttat aatgaagtgg tcactattac
    14161 tccaagaaat tatcgtttcg attttagaaa ggtaaaaaat ttagataaac attatgcaat
    14221 gataggaata gcagctgggg tatccaacta tccactctat tatgaggcta caaatgaaaa
    14281 agggttgagt atggcaggac tgaattttcc tggcaatgct gattataaag aattacaaga
    14341 aggaaaagat aacgttgcac catttgagtt tattccatgg atactagggc aatgctcaac
    14401 catagacgaa gctaaagaat tattggctac tatcaatcta gtcaatatcg attttagtga
    14461 aaaactaccc ttgtcacctt tacactggtt attagctgat aaagaaaaat cgatagtaat
    14521 tgaaagtatg aaagatggac ttcatttata tgataatcct gtcggtgtgt tgacaaataa
    14581 tccgccattt gattatcaat tatttaatct gaacaattat cgctcgctat caaatggaac
    14641 accagaaaat catttttcaa accagatcag cttgaatgtt tatagtcgtg ggatgggagg
    14701 attgggctta cctggagatc tctcttctgt ttctcgattt gtaaaagcca catttactaa
    14761 aatgaatgct gcatcaggtg attcagaatc tgaaagtatc agtcaatttt ttcatatact
    14821 aggctcagtc gagcaacaaa aaggagtatg cgatactgga gaaagaaaat acgaatatac
    14881 gatttattct tcttgctgta acgttgataa agggatttat tattatcgta cgtatgaaga
    14941 cagtcaaatt actgctgtaa atatgaataa agaagacttg gatcgtcatg aattggtcag
    15001 ttatccagtc ataaaagagc aacagataaa ctatgtcaat taattaatga atagatccgt
    15061 ttggtatcat attttctgat acagtcataa ttagacacga tctttaggtc gtgtcttttt
    15121 ttgctggttt ttttggaaat agcatccact aatatttttt taacacgaag agaataaggt
    15181 agcctcaaaa aagaaaacat ggtaaattag atattgggac tttattttct gtaaaaacag
    15241 aaactttcat cttttgtttt cacgtgacga aattgtaaga gagaaaatat tcgtccgcta
    15301 tttattctat gataagatgc atatgaatga aataaacagt aattttatat taggatgtga
    15361 aagttaaatg tgcggtattg taggttttgt taacgacaag gacaacaaaa aaacaattat
    15421 taatacaatg atggatcgaa tcgttcaccg tggacctaat agttcaggag aatatatcga
    15481 taaacatgtt gctttaggat tcagaagatt aagtattatt gacttagagg gcggtactca
    15541 gcctatttac aatgaagatc ggacaaagat cattattttt aatggcgaaa tctataatta
    15601 ccagcctttg agagaagaat tgattgcagc tggccacgtt tttcaaacac atgcagatac
    15661 agaagtcctt ttgcatggtt acgaagaatg gggaacagaa ttattgcaaa agatccgcgg
    15721 aatgtttgct tttgctattt gggataatga aaagaatgag ttattcggtg caagagacca
    15781 ctttgggatc aaaccatatt attatgcaga aatgaacgga acatttatgt ttggttcaga
    15841 aatcaaaagt tttctgcctc atcctgattt taacaaagaa ttgaacaaag aagcgttgaa
    15901 accttatatg actttccaat attctccatt aaacggcgaa acattcttca aagatgtcta
    15961 tcgtttgcct gaaggccatt attatacgta taaagatgga aaaatagaca ttcagcaata
    16021 ttgggatgca gattttgaaa caaaagaaac gcattcccga caagaatgga tcgaaaaaat
    16081 cgacgaaacc gttcaagctt ctattgaagc acatacggtc agtgatgtag aagttggttc
    16141 tttcttatcc agcggggttg attccagtta tgtaacctct gtattgaaac cagatcattc
    16201 tttctcaatc gggtttgatg ataaaaccta taatgaagcg attgaagcca gaaaactaac
    16261 cgaactattg gacttagata atacagcagc agtgatcgac ggagacatgt cgttcaaagc
    16321 attccctttg atccagtatc acttagatga acctgattca aatccttctt gcgtaccttt
    16381 gtacttttta gcaaatcttg cttcacaaag tgtgcgggta gtccaatctg gagaaggggc
    16441 ggatgaactg tttgcgggat accaaacgta tggattccat acgaattcaa aattcatccg
    16501 tgtgattgct caaggattga aaaaattacc aaaaggaaca cgctataatt taggacgtaa
    16561 aatcggaaaa atgaaaaatt tccatggacg gatccattta tatgaatcac ttgctcctgc
    16621 aaaagaatat tttatcggtc atgctcgagt gttcgaagaa tcagaagcat cagaagtgtt
    16681 aacaccaaaa tatcaaacag caccatctgt ggatgaaatc atgactgttc attacgagaa
    16741 aacagaagga atcaaagatg aagtcaataa gatgcaatat gtcgatcttc atcaatggat
    16801 gccaaaagat atcttgttaa aggcagataa actttctatg gcaagttctt tggaagtccg
    16861 agtaccttta ttggatatcg aagtcatgaa attggctcaa caaataccaa gtaagttttt
    16921 attgaatcaa aacaacacaa aagatatttt cagacaagct gcgaacaaac atcttccgga
    16981 aaaatggtcg aatcgtgtga aattaggatt ccctgtgcca atcaaagctt ggttgaaaga
    17041 agaacacggc tacgaacaag tcaaagcatt gttcgaagca gattttgcaa aagaattttt
    17101 tgatcaagaa aaaatcatga agttgctaga tgaccatcac gaaggacgta aagaagagca
    17161 aagaaaaatc tggacaatct tcagtttctt gacatggtat aaagtctact ttgtagatga
    17221 aacgattccg caagcagaag caatcgacta tgtgactgtt tgatgaaaat caaatatcaa
    17281 taaaaaagag gttttctcct accgtttaac actgagtgat aagaaacaat ttcaaaaaac
    17341 agctcttccc gttttataga tattatgact tatggttcgg agttggcaga ggaacaccat
    17401 tgtttcgaac ataagggggt tgtgacacga ttttcgtcac aaccccttta catatgttca
    17461 ataatcgatt tctttttctt ttgtcccatc ttttttataa atgaacaaag ttgattcttt
    17521 gttttgtgct acttgctttc ctttttcgat tgcttctttt tttgtatcaa aatggttgct
    17581 tgcctttttt gcccctttag atttcacgat ccattgttct tcctcatatt ctacgatcac
    17641 atctgaatca agcagttttc cagcacgagg attcgtatcg tgttcatccg tcttgcttgg
    17701 atttttttct ttttcgaaag ttcgtttttc tgattcacta gcatcttcat accatttttt
    17761 tgcttgatca atggcaattg ggatcgcacg gttatcaggg tacccttcat ctaataatgc
    17821 atttgcgatg tcgattgctt tttttcttgt caatttatct aagtttttca ttgatgcagg
    17881 aaagtccttc atgttccatg gcatattagt atcccccttt attaaaaaac ataatctata
    17941 taaacaagtg taagggtatt tatacaaaaa gaaaaagatt ttgtttgaga agtaaaaccg
    18001 ttgtatttat cgtcaagtag ttttacttaa caaaatcgtg aaaaacacta gcaatctaga
    18061 aaaaatcatg gtaagataat caagtctgag agtcatctta gaggattctt gtaaaaatgg
    18121 gagggaaaaa catgcgcgta aacatcactt tagagtgtac ttcttgtaaa gaacgtaact
    18181 atctaacaag caaaaacaaa cgtaacaatc ctgatcgttt ggaaaaacaa aaatattgcc
    18241 cacgcgaacg caaagttact ttgcaccgtg aaacaaaata atgtttttaa agttctcaat
    18301 tccttgctgg tcaaagaatt gagacttttt ttatctcaaa acatctaaaa tcataaggag
    18361 cggataatat gtttatttcc atgtgggcac aagataaaaa tggtctgatc ggcaaaaatg
    18421 gtttgttacc atggcgattg ccaaatgata tgcgtttctt tcgcgaacat acaatggatc
    18481 gaattttagt gatgggaaga aagacctatg aaggaatggg ggatctttca cttccttatc
    18541 gccatatcat cgtgttgaca acgcagccaa attttcgcac gaaagaaaat gcggaagtaa
    18601 tgcattcgat cgatgaactt ttgtcgtata gtcaaacgat ctcagaagat atctatgttt
    18661 cgggtggtag tcggattttt caagaacttc ttccttacac tggtcggatc tggcgaacat
    18721 tgatcgatag cacgtttgaa ggcgatacgt atattgggaa tattgatttt tcagacttcg
    18781 cccttataga ggagtatgag gggataacgg atcaagaaaa tctatatgcc catcgttttc
    18841 aaaaatggga aagagtaaaa aatagggttg cttcaaaaga agaataaaat ctatgcgtct
    18901 agtttgttaa taagaaaaaa agcatatcac gactaatcgt gaagatgctt tttttagtta
    18961 aaatcaattt agtttttctt tgatatcatt gaccatttcc tgactggcaa taggtccgtt
    19021 atatagccaa ctagattcag gtccgaattg cagtacatga ttgtctgtca ctgctttaag
    19081 attcttccag cttggttcat tgaacatggc agcatctttg tcactgttca caaggatgat
    19141 gtagtcagca tctaattcag ctagcttttc agaggaaaca gcagaccagt cagaagtggc
    19201 ttttttggag acctcttcca ctagatcagg aacaccaaat tccagatcgt cgtatacgat
    19261 tcttccactt gaccgatttt tgctgaccat aaaggctgag ttgttggtca cccacaacac
    19321 tgcagctgtc ttgttctcga ttttatctgc tagttcttct cgagttttct tgatggattt
    19381 ttgataatcg gaaatgatct tttctgcctc tttttctttt gccaaagctt tgccgacatc
    19441 ttttagttgt tcttcccatg tgacatctgt tccgtttttt acaacataag ttggcgcgat
    19501 tttgctatat tgttcgtatt tcccgccttc gacagtagcg gaagaagaaa tcaacagcaa
    19561 atcaggctca aagcttaaca ctttctcata aggaaggtca taagaaatcg ttgggacatc
    19621 ctttaaatca tcttgcagat aatcttgaat ggaaccactg ccaacagtcc actgggcgat
    19681 aggtttttcc cctagtgcaa tcagatagtc ttctaagtaa ctgccgatga tccgtttggg
    19741 cgcgtttgga atctctactt tatgtccaag tgtatctgtg actgtatgag tactattgga
    19801 tgaagtcgtc gaattggcag ttgtagctgt ttctttatct gaagaggggg agcaagcgct
    19861 cagtactcca gccagcagca atatgctaga taatgtgaat acttttgttt ttaatttcat
    19921 ttctttcctc ctaacataat tgagaatctt tctcattggt tattattcct gatatttcga
    19981 acgctgtcaa ccgcttcatt tggctataga tatgaaagta gcgcttgacg aaatgttgaa
    20041 acagcgtcat aattgagaat gattttcagc gaaaggatgg gtgaaatgac gagattaaga
    20101 gcagctgaca ttgcagccgg ctacgaaaac aaaaaaatca ttgaaaacat gtctgttacg
    20161 attcctgaag ggaaaatcac tagtttgatt gggccaaatg gaagtggaaa atctacttta
    20221 ttgaaaagtt ttacccgtat actacctgtg aaatcaggaa agatcattgt caataactct
    20281 gatatctcta catacagttc aaaagaactt gcaaaaaaaa ttgcattatt agcacaaact
    20341 agtgaacacc ctacaggtat gacagtagaa gaagtagtat cttacggacg atacccttat
    20401 caaaaactgt tcagtggcat ggacacgcaa gatcatgaag caatcgagtg ggcgttggat
    20461 gctacaggtc tagctggatt tcgtatgcgg gatatcgcaa cgctgtctgg tggacaaacc
    20521 cagcgtgtct ggatcgctat ggcgcttgct caggaaacag atatcttgat cttggatgaa
    20581 ccgacaacat ttttagatcc ggcacaccaa ttagagatcc tacagttatt gactgaaatc
    20641 aatcaaatga aacaaacaac gatcttgatg tcgattcatg acattaatca tgcttcacgt
    20701 ttttcagatt atttattagc aatgaaaaac ggtaagttga tcacagaagg tacacctgaa
    20761 gaagtgatca caaaagagtg tatgaaaaaa atatttgaga ttgatgcaac gattgtcacg
    20821 cttccaagaa caaataaacc agtttttcta acctatgatt tgttgccaaa agagcaggag
    20881 gatcaattat gaggactatg aagaaaaata gactcctgct tttggtctgt tttgttcttt
    20941 tgattatttt ttttgttgct ctttcaaatg gcgcagcgac tgtgggaaaa gcagattttt
    21001 ggcaggcgtt gtttgatttt gatagatcaa aacaaagtca ccaaatcata cgaaatattc
    21061 gtttgcctcg tgtggcggga gcatttcttg tagggagttg ttttgcattg agcggtgcat
    21121 tgatgcaagg agtgacaaga aatcctttag cagattcagg cttactagga atcaacgcgg
    21181 gtgcttcgtt ggcaatggcc cttagttttg ctttttggcc taaagcttct gatttttctg
    21241 tgtttctaat gtcattggca ggttcttttg ctgtaacttt gctcgtattt ggttttttgc
    21301 agttttcgaa aatgggcatg aatcctttac agctgatttt agctggcgta gctattagtt
    21361 ctttttttac tgctatcagc caagcactta cccaattctt taatctgcag caggatcttg
    21421 ctttttggtt tgtaggcgga gctgccaata tcacatggaa acaattagca gtattgtttc
    21481 ctttatatat acttgctgtt ttggtttctt tttcattagg aaaagcaata tctttgattc
    21541 atttgagtga aacacatgca ttagctcttg gaagtcatcc taaacgaacg cggttgattg
    21601 ttttctgtct agttgcagtg ttagcagcca ttgccgtttc gttagtcgga cctgtttcat
    21661 ttattgggct gttggttccg ccagttgttc gcggaatggt tggaacggac tatcgttatg
    21721 ttctacctgt ctctttttta gttggcggtg gattggttat gttggcggat tttacagcga
    21781 ggatgatcaa tccccctttt gaaacacctt ttggattagt cattgcattg attggcgttc
    21841 cgtttttact gatacaagta aggagggaac aacggtgaaa aaaatatatt ggacgttcta
    21901 tttcttgctt tttgtacttg tcatcctgtc tataggtagt ttaatgattg gtacgccttt
    21961 tatttacctg gatcagcttt ttgccacgtt catagggaaa gaatcatctt ctttggcgct
    22021 gattgttaga gaatttcgag ttcctcgatt actgatcagt ttattagcag gagcttgtct
    22081 tggcgtttct ggttatatct tgcaaggagt aacaagaaat gaattggcag attctagtat
    22141 attgggcatt aatgccggag caggattttt agtgatgctt tatttaggtt tcttttcgca
    22201 ctattcgctg ccgtttctat tgctagttgt agcctttcta ggtggtgttt tagctgcttg
    22261 ctgtgtctat cttgcggcct atgatcgaaa tggctttttg ggtatgaatc gaatcttatt
    22321 gtccggtatt gccgttaatg ccggcctttc tgcattaaca ttgctatgca cgatccaatt
    22381 atctaaggaa aattatggat ttgtgaatgc atggttagcg ggatcaatct ggggtgcgag
    22441 ctggccttat gtttgggcat tgcttccatg ggcggttatc ttaattccgc taggaggact
    22501 ttatgcacag aggattgtat tgctatcatt tggtcaagaa cgcgcgcaag gattaggcct
    22561 taacgtggct aaaagtcaaa aaatcctttt gttgttagct gttgctttgg caagcggtag
    22621 tgtagcggtg acaggtagtt tatcttttgt aggactacta gctcctcatg ctgcgaagct
    22681 agtcgtacgt aaagaaaata actggacctt tgttctgagc ggtttgttcg gttccatttt
    22741 tctgcttagt gcagatatgg ttgctagagt gattctacta agtggggaag tacctacagg
    22801 aattttgatt gccctttttg gtgcgccata ttttctgtat gcacttttta tcagacaaaa
    22861 acacgcgctg aacagttgaa attcattaaa aaaggaaggc caatcatttc taggtcttct
    22921 ttttattcta tttatgcatt tatttgaaag ttcgattgct atttttcttt ttttcctata
    22981 ccattttatg agagaaggaa gggtgagttt ttggaccaat tgaaagtaag attacgccgg
    23041 aaaggaatcg aaaagctgaa aaatctggcc aaaagtggca agaaaaagga aaaagaacag
    23101 cgaatctata aacagctatt cgccagcgag tactggaagt cagcaaaagt gatagggacg
    23161 actttatcga atgaatttga actggataca cagccggtta tccaacgagc agaaaaagaa
    23221 caaaagaaaa tagttgtacc taaaactttg ccgaaacgtc agatggcgtt ttatgaaatg
    23281 gatgaacagt ccgttcttgt acgttcgagt tttggtgttc ttgagccaca atcagagaag
    23341 ctctatttgc cggagatgat cgatctcctc attgtaccag gtattatcta caatagagcc
    23401 ggttatcgaa tcggttttgg cggtggttat tacgaccggt atttaaataa ttttcataaa
    23461 aaaacatgta gccttgtttt tcgtgaacaa ttgaatgaac aatggcaacc ggagagcttt
    23521 gatcagaaga tccaacaatt gtttattgac taaaatgaaa tgggaggttt tcatgaatta
    23581 tcaacagcaa ataaaattgc gtgtatggtt aagacgaccg ttatggacct atgctttttt
    23641 agggatacag acagcggtct tcctcatgat ggaattattt ccgcgacttg agatccctta
    23701 ttatgccgga atgtatggtc cttatcttgt tcacttcaat gaatggtggc gtttagtgac
    23761 accaatcttc atccattttg gactgatgca tttcgtaatg aactcactga tactgtattt
    23821 tatggggcag caaatcgagg caatctatgg ccattggcgt tttttcttga tttatatgtt
    23881 cagcgggata atgggaaata cagcaagctt tgcttttaac gaagcgaatg ttctgtctgg
    23941 tggtgcaagt acttcgatat tcggtttgtt cggtgcgttg tttatcttag ggtttcattt
    24001 taaacataac ccagcgatcc agcagctagt cagacatttt cttttattta ttgtgttgac
    24061 atttgttttt ggtcttctgg atacctctgt agatgtttgg ggacatgtcg gtgggctaat
    24121 tggcggatta gtgttaggga atgttttggg tctaccgaaa caacagacaa gctattcgat
    24181 acaccaaagg attctttcta cactagtttt tgtatttctt tttgtaatat gtattttact
    24241 gggtttaaaa aaatatggtt tacttgtata atatgaagga agtgcttaaa gatggagagc
    24301 ttatatgatg tacagcagct gttcaaaaaa tttggcatct ttatctatgt gggtgcacgc
    24361 atctatgaca ttgaattaat gactatcgaa ttgcgtaatc tgtatgatag ccgtttgatt
    24421 gatcatgata catacatgac agcgtggcgc atattaaaaa gagagcaccg aattgaagaa
    24481 agccgaaaga aaggaaattt gtaatggaca agaagattat tgggattgat ttaggtggaa
    24541 caacagcaaa atttgcaatt ttaacaccag aaggagagat tcagcaaaaa tggagcatcg
    24601 ataccaatat tttggatgat ggtaagcata tcgttcctga aatcattgaa tcaatcaatc
    24661 atcgtttgaa tttatataat atgaaagccg aagactttat cggaatcggc atgggtaccc
    24721 caggaagcgt ggacagcgaa gctggaacgg ttattggtgc gtataactta aactggacag
    24781 aagttcaatt tgtgaaaaaa ctgatcgagg caggaacagg aatcaaattc gctatcgata
    24841 atgacgcgaa tgttgctgct ttaggtgaac gatggaaagg tgctggagaa aacgatccag
    24901 acgttgtatt cgttactcta ggaacaggtg ttggcggagg tatcgttgct ggcggaaatt
    24961 tgattcacgg cgtgagcgga gctggaggag aaatcggaca tatcactgtg gatcctgaag
    25021 ggttcgaatg tacttgcggt aaacgcggat gtttagaaac tgtatctagc gctacaggtg
    25081 tggtacgcct aggtcgtttc ttggcagaag aatacgcagg ggattcaaaa ctgaaagcaa
    25141 tgctagacaa cggagaagaa gtaacaagta aagatatctt tgaaatggct caagaagacg
    25201 atccgtttgc attgatggtt gttgatcgcg tatgcttcta cttaggttta gcttgcggaa
    25261 acttggggaa tacattaaat ccgtcaagta tcgtgttagg tggaggagta tcggcagcag
    25321 gagaattttt acgtagccgt gtagagaaat attttaaaga atttactttc ccgcaagtaa
    25381 gagaatcaac aaaaatcaaa ttagcagagc ttggtaatga agctggtgtc attggtgctg
    25441 cctcattagc cttgaaattt gcttaaaaaa acggaggcat tacatggttt tatgggtaat
    25501 taatatcatt ttgctattga ttgtgcttgc aatcatcctt tgggaagtct atctacgagt
    25561 aatggccaaa cgttcagcaa cgactttgac agaagaagaa tttcgagaag gaatgagaaa
    25621 agcacaagta atcgatgttc gcgaaaaaga tgtgtttgat gctgggcata ttttaggtgc
    25681 aagaaacatc ccttacactg ttttgaaaga ttcattagga tctattcgaa aagaccagcc
    25741 tgtctatatt tacgatcaaa agaaaagttt gagcatccgt acagcaaata aattacgtaa
    25801 agcaggttat caagagattt atttacttaa gggtggatat gacggatggt ctggaaaaat
    25861 caaaagtaaa aaagtataaa acagatgatt gtatgacagc tttaaaaacc gaatcaatca
    25921 ttagattttg accaagatca catgaacggc gcaatggata gttgtgccgt tcattttttt
    25981 tattttgtgc tattatctac atatataagc taagcgaaaa ggtagaaaga aggaaacaac
    26041 tatgatcaaa ttaaaacgtg tttaccttga tgctgaaaaa gaggatggct atagaatact
    26101 cgtggataga ttctggccac gaggaatttc aaaagaaaaa gcgcagttag atctgtggtt
    26161 gaaagaaatt gcacctagta atgaagcacg caaaactttt gaccatgtac cagaacgatt
    26221 tgcttcattt gcaaagaaat accagcaaga attgattttc gaagaagaaa agaagcaagc
    26281 tatttttaaa ctcagtcaac ttatgaaaga acatccagtc attacttttg tttatggtgc
    26341 aaaaaatgaa catcagaacc atgctgtttt attgaaaaaa tttatcgaaa tggaggcatg
    26401 caaatgaaaa tagggatcat tggtgccgga cctagaggat taagtgtagc agaaaggatt
    26461 ctccataata atcaggacag acattctctt gaactttttc ttttcgatcc caatggtcct
    26521 ggaggtcgag tttggcggtt gaatcagcca ccggagttat taatgaattc tgtttctcaa
    26581 caagtgacgc tttttacaga tgaaacattg tccagtggag gattggtaac acagggaccc
    26641 aacttgtttc aatggagtaa aggacctgct acagattata tcgaacagac ggtaaccaaa
    26701 aataagcaac taattataga agaaatcaat cgtctggaaa aagatcagca atctactcga
    26761 tgtttatacg gactctatca acgctggttt ttctcaaagt tgcaagaaga atttccagct
    26821 tctattcagt ttgtttattc tttagtaaaa aaagtaagca aaagaaaaga tggttatctt
    26881 ttacagacag atcagcaaag ctattctatc gatcagcttg ttttagcaag cggtcactgg
    26941 gaaaatgatg agacagaaga agaaagagtg tgggtagact acgcaaagaa aaatgtttta
    27001 ctgtatcagc ttccttctaa tcctgcagat gtagatcttt cgaagatacc gcctaaagaa
    27061 aatgtctttt taagaggtct aggcttaagt ttttttgatt atgtcggatt gtttacagta
    27121 tcaagaggag ggcgcttcga gaacgaaaag ggaaaactgg tctatcatcc atcaggcaag
    27181 gaaccgattg tatacagtgg atcaagaagg gggctccctt attaccctcg aggaagaaat
    27241 caaaagcaag gcggagcaat ggcatggcca cggttactaa caaatgaaaa cctggagcaa
    27301 tggcatcagt cgggattttt gactggcgaa acattttttg actatctgaa aaaagacgtt
    27361 gagttgtttt attacaagaa aatcatcgaa gaatatcact tgccgattcc aaagaaaaat
    27421 tttgagcatg attttctctc cctctcttca gaggagtgtc tcggaaagca tccagcacta
    27481 atcccttata gatgggattg gtcgtattta gaaactcctc ttgcctatca gaatgagccc
    27541 ttttcagaag ctagccgaat atttattgaa gggcagataa aagaagcgga aaaaggcaat
    27601 tgcacaggag catttgcttc aacatttgat gcattaaaag actggcgtga tccaatccgg
    27661 caggctattg aatggcacgt tttttctgct aaggaataca aagaaatact atggggatgg
    27721 tttactcatc taaatagctt tttaacgatc ggtccgccaa tcattcggac gaaagaatta
    27781 gcagcactga tagatgcggg tatttttcat ttgatcgaac cgccatttga tattcagcaa
    27841 aagcacaacc gctatgttat ttctctacaa gataaagaaa tcagcagtcg ctatttgatt
    27901 gaagctcgat tgccacaaac aagcttttct cgttcaagta atcctgtcat aaaaaatttg
    27961 aaggaaaaca aacttgttcg ccctttttca ttttcagata atacaggaag ttatcattca
    28021 gaagctatag atgttgagcg aggtacgaat cgcgtgattg atgcttcagg ggaaatccag
    28081 tctgactttt attgctatgg aatacctgtt gaaggtgtgg attggctaac tgcagcagta
    28141 gctagacctt atacagatcc atggaatctg agacaggcag ataaaatagc acaacttata
    28201 ttgactgaca aataaaaata cgcatgatga cttatctgtt ttttagaaag tcttcatgcg
    28261 tatttttaaa taattattaa cgagaaacgc gtttacgcat tgctttttta cggttttctt
    28321 cgatcattgc ttctttttcg tcaattggat cgatcactgt ttttttcaca gaagcaacca
    28381 aaccagcaac ggcagcggct gttgccagac ttcctactaa tattccagat acaaattttt
    28441 tcattgaatc cacctcattt attatttgtt atatctatta tggaacaaaa gagaaaaaaa
    28501 ggct
//
LOCUS       DAZKCH010000032        27962 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000032 DAZKCH010000000
VERSION     DAZKCH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.032"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(395..1339)
                     /locus_tag="ACG84X_001394"
     CDS             complement(395..1339)
                     /locus_tag="ACG84X_001394"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFP9127275.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1635..2579)
                     /locus_tag="ACG84X_001395"
     CDS             complement(1635..2579)
                     /locus_tag="ACG84X_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFP9127276.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2800..4014
                     /locus_tag="ACG84X_001396"
     CDS             2800..4014
                     /locus_tag="ACG84X_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9127277.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4036..6051
                     /locus_tag="ACG84X_001397"
     CDS             4036..6051
                     /locus_tag="ACG84X_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFP9127278.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6134..7507)
                     /locus_tag="ACG84X_001398"
     CDS             complement(6134..7507)
                     /locus_tag="ACG84X_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFP9127279.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7533..7817)
                     /locus_tag="ACG84X_001399"
     CDS             complement(7533..7817)
                     /locus_tag="ACG84X_001399"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9127280.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7819..9834)
                     /locus_tag="ACG84X_001400"
     CDS             complement(7819..9834)
                     /locus_tag="ACG84X_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFP9127281.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10013..10318)
                     /locus_tag="ACG84X_001401"
     CDS             complement(10013..10318)
                     /locus_tag="ACG84X_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFP9127282.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10407..11438)
                     /locus_tag="ACG84X_001402"
     CDS             complement(10407..11438)
                     /locus_tag="ACG84X_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9127283.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11645..12520
                     /locus_tag="ACG84X_001403"
     CDS             11645..12520
                     /locus_tag="ACG84X_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9127284.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12672..13514)
                     /locus_tag="ACG84X_001404"
     CDS             complement(12672..13514)
                     /locus_tag="ACG84X_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9127285.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13606..15483)
                     /locus_tag="ACG84X_001405"
     CDS             complement(13606..15483)
                     /locus_tag="ACG84X_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFP9127286.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15480..16901)
                     /locus_tag="ACG84X_001406"
     CDS             complement(15480..16901)
                     /locus_tag="ACG84X_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFP9127287.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16904..20293)
                     /locus_tag="ACG84X_001407"
     CDS             complement(16904..20293)
                     /locus_tag="ACG84X_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFP9127288.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20550..21941
                     /locus_tag="ACG84X_001408"
     CDS             20550..21941
                     /locus_tag="ACG84X_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127289.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22014..22661)
                     /locus_tag="ACG84X_001409"
     CDS             complement(22014..22661)
                     /locus_tag="ACG84X_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9127290.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22669..23355)
                     /locus_tag="ACG84X_001410"
     CDS             complement(22669..23355)
                     /locus_tag="ACG84X_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127291.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23361..24434)
                     /locus_tag="ACG84X_001411"
     CDS             complement(23361..24434)
                     /locus_tag="ACG84X_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127292.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24656..25330
                     /locus_tag="ACG84X_001412"
     CDS             24656..25330
                     /locus_tag="ACG84X_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9127293.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25335..26675
                     /locus_tag="ACG84X_001413"
     CDS             25335..26675
                     /locus_tag="ACG84X_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFP9127294.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26824..27810)
                     /locus_tag="ACG84X_001414"
     CDS             complement(26824..27810)
                     /locus_tag="ACG84X_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFP9127295.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8164 a         5269 c         5063 g         9466 t
ORIGIN      
        1 tttatcaaaa atcgtcattt ttccatcaaa atctgcttat gcaaaattat aaaaaaattt
       61 tgcagttttt cttacttttt ttgtcgttta attgaatgat aaaaaccagt ttctttattc
      121 agttaatcaa atatgaacga attagatatg aatcattgta tttgccgttg cggaaggatt
      181 ttttaattaa ccacagataa acattgataa cgattcgctt attgtaatca acagattaaa
      241 tttcatatgt tcatatgtac ggatacattt tcggaccgat taattttaac cattctgttt
      301 atttgcttac ctattagata tcaataaaaa actgcttaac agctatttca gctgttaagc
      361 agttttagga tttttagttc atattcattg tttcttataa tacagtgttc aatacttctc
      421 ttaaagcact tgttgatttg ctgaacattg ctttttcttc ttcgttgatt gataattcaa
      481 caacttcacg aacaccattt tcgtcaacga ttgatggcac acctgtaaag atatcttttt
      541 cgtcgtattc accagttaaa taagcagata caggcaatac agcttgttcg ttattcaaga
      601 tagcttttac gatacgtgca gtactcatac caataccata gtaagttgct tttttacgat
      661 caatgatctc ataagcagca ttacggactt tatcagcaat cacatctaat tcatcttggg
      721 caatacgatg gtctttttct acaatttcaa acactggttt accaccgaca gttgtatgtg
      781 accatgcagc aacttctgaa tcaccatgtt cacctaagat atagccgtgg acgctgcgtg
      841 ggtcaacttt taatttcaat gcgatttctt tacggaaacg agttgtatcc aatgttgttc
      901 cagtaccgat aacacgtgat gttggcagac cagattcgtt ccaagcgata tatgtcaaaa
      961 tatctactgg gtttgaagca acaacgataa taccgtcgaa tcctgatccc atgatttctt
     1021 ttacgatttg gcgcatgatt gacgcatttg ttttaactaa atctaaacga gattgaccag
     1081 gtttttggtt gataccagct gtgataacaa cgatatcagc atctttacat tcttcatagc
     1141 cacctgacca tacagccaca ttttcatcgc cccaagccat accatctaaa aggtccaatg
     1201 cttccccttc tgctttttct tgattcacat cgatcaatac taattcatta gagattcctt
     1261 ggttgatcat tgcataagcg atacttgttc caacaaaacc tgtaccgacg attactactt
     1321 tacgacttgt ttttttcatg aataaacagc tccttttcat aactatttgt tactttcatg
     1381 aaaagtatag tcttgtttat tcattttatc aacatgttaa ttataatagt tgttattata
     1441 atttttgatg gaaacgaatt cctgaatacg cataacagat aaatgacaaa tgtttacacc
     1501 tatatcccct gataatacaa ccaaaagttt agaactgaaa ataaatccaa aaaaattcgc
     1561 tgcaacgata taataagaca gcaatcgcac ctaaaacaat tttccttcat atgctttagt
     1621 gaaagatttt cttcttaatg tttatttctc cattcattgg gagtacatgt tgaatacttc
     1681 ttgaataatt tgaataaaga agtcgtttgt ttatatccga tacgattagc gatttcttcc
     1741 aacgaaaaac tcgtttcttg aatcagttcc aacgcaaagt cgaatttttt ctttagaacc
     1801 agttcttgaa aggaagcatc aaaatacatt ttcaatttat tactaagata gaccggattg
     1861 tagccaaaat gagctgctgt ttcttttaac gtacaagaag taaaatgctt atcgatataa
     1921 tctaatactc taagcatctc attttctgcg catccatctg ctgatgaaaa gctttgttgt
     1981 tctaataaat gagtcaattc gatcagtaat agtgatgtat agagatttaa cgaacggatc
     2041 ttatgactgt atgtatcaaa ataaatcaac agcatatttt caatcaaatg cgtcaaacga
     2101 cttgtttttc cgccgcgaaa atgaatgaat tgtgtatgtt cccctttttc ttttgatgca
     2161 tttatcaaaa aagaagaaag tagattattt gtgcttgcca aatgattcaa tatctctgta
     2221 gataaggttt cttcttttaa taagatgttg attaaaatat cctcttgccc tgtgtattcg
     2281 attctttgag tagcttcttt atcaatgatc accacgtcac tttcttccat ctctatcctt
     2341 tctccattaa taatttgtaa acatgtaccg ctatacatat aattgatttc aacaaaatca
     2401 tgtgtatgct cgggaacttc cgcatatcga cggtgtttac tgatatgaat atttccctgt
     2461 tgaaatagat cccctcggtg gatttttggc ggtgtctgaa gatggtaagc taagtttaaa
     2521 tcattgatat tcattccttg ttcacgctgc agagtttcga ttgattcttc gttacgcaaa
     2581 aaaaatgtct aattcagcta gttccaattg actccctcct ttttgtaagc ggtttctttc
     2641 gcttattagt tcacgctgta ctgctattat atgcaaagct atttttggtt tcataaagac
     2701 tttctatggt tgggacatga acttcctgtg attccgctat tgagagaata accacttcat
     2761 actatatttt tgataagcgc ttacaaaaat gaaaggaaca tgcttatgaa taaaaagatg
     2821 atgaaatttt ctctgctgtc agtctctctt attttgactt ctgctggtgc agtcacgtct
     2881 gcaattccca gtatgtcagc tacttatgcc acgcgttctt tatctgctgt tgaattatta
     2941 acgactgctc cctcttttat ggtcactatt tttgttttga ttagtagttt tattgctagg
     3001 aaaatcggac aaaaacaaac tgtgatcatc ggattagtga ttgcatcgat ttgtggtatc
     3061 ctccccctct tctcacaaag ttacagtatt gtcttagctt caagagctgg actaggtatt
     3121 ggctttggat tgatcaattc tttggcagtc agcatgattg ctgcctttta tcacggagat
     3181 gaacgagcct ctatgattgg ttttcaaagt gcatttcaag gatttggtgc agctttaatg
     3241 acatttgttg caggacagct agtacagttc ggttggcaat ataccttttt agtctacgcc
     3301 atcagcttac ctattcttgt cttgtttgtt ttgtttgttc ctacacctga aacaactgaa
     3361 cttcaatcgc atggcacagc cccaacaaga caagtaatca aaacgaatcc taaaatgatt
     3421 agttatggta tttttctctt gctggtcatc gtggtatata atgctgtatc gattaaatta
     3481 gccacagtcc tgacgactta ttctctagga aacgaaacta atgcagcgaa tatcttaaca
     3541 atcatgcaat tggcaagtat ggctgccgga gtttgttttg gctggcttca gacaaaagca
     3601 catcgctata tgcttacact ttctttacta ctgatgggaa tcggctttgt attgattgcc
     3661 actgtgataa acctgtatgt gattgggttt ggtgcgatcc taacaggaat ttctttttcg
     3721 ttattcattc cttacttatt caaccaagta agtatccaag cgcccaagta cgcggagagt
     3781 ttcaatactt caatcttatt ggttggcgct aatttaggta ctttcattgc accatatggt
     3841 ttgctctttc tctcttttgc ttctcttggg agtaaaacac ttgctgtttt cgtcaatggc
     3901 agtatcttgc tgttgattag cgcgcttatt agccttctag tagtacacag gacgaataga
     3961 aagacagtga taagagtaga tgaagaaata aaagaacaat tgacaacaaa ataaatttga
     4021 tggaggtcgt gtaaaatgac aaatgaaaaa cataaagata gatggctttg gtatcctgga
     4081 gactttgaga tccgccatgg actgctacaa aatttccaac gggaagaacg aggttttgac
     4141 tggccagcgt actggtacat ggatgattgc catcggaacg tcaagtttaa gagatattac
     4201 tttcttgatc aaccttccat gtttaaagtg acgatccaag gagttgggta tgtagaaatt
     4261 aatggacaaa aacatccatg tggaaaatgg ctgacttgtc cagctggtaa agcaaaaatt
     4321 cgtatctttg taggacatac atcagggcta ccagcgatgt ttatcgaggg agacgaagta
     4381 aaatcagata ttggctggac agcaagtaat tttattgaag aatatccagc tggctggagt
     4441 ccgctttatg tcgatatcgc aaaagatcca aatcaaatct attatcaaaa agaatgcgtc
     4501 catccagtca ctgaaacgga gattggcgga ggaatcttat tcgattttgg gcgagcagtg
     4561 aatggctgtg tagaactaat atctctggat gaccatatcg aatctatcac tctatgttat
     4621 ggagagtccg atgtagaagc tatggatatc gattattgct actataagca aataggaatg
     4681 acaagaaaaa tgaaagctcg taaacgcgct tttcgctatt tgtttatacc agaggtttct
     4741 actggaatgg ttcaacttca agtttttcat gaatttttat ctctttcgaa acaagctgct
     4801 ttttcaagcg attcttcttt actgaatcag atctggtcag tatcagaaga agccttcaag
     4861 ttatgtagtg atttgttttt tatcgacggt atcaaacgag atcgctggat ttggtctgga
     4921 gatgcgtatc aatcattcat gatcaatcaa tatctttttt ttgacgagga aatcaataaa
     4981 cgaacgatat tagcattaag aggacaaaat gaaatcaagc agcatatgaa tactatcgtt
     5041 gactattcga tcttgtggtt gattggtatc gaaaaccact atatgatgac gaaagactat
     5101 gaatttttac gcatcgtcta ccctaagatg caatcattaa tgagatactt gatggagcaa
     5161 acgaatgaat tagggtttat ttatgggaga gcaaaagatt ggatatttat tgattggtct
     5221 gaaatggata aagaaggaac gcttgctgca gaacaagtct tattactgaa agcctatcat
     5281 tccatgatca cttgcggaga tatcttagct gaaacatatg gagagaacga aaattatcat
     5341 actcatctct atcaagaaaa atatcaacta ttgaaacaaa acctatttga ctacttttgg
     5401 gatgaagaac ttggcgcttt tatcgattgc tatgaatctg ggagaagaaa tgtgacgcgt
     5461 catgcgaata ttttcgctgt tttattcgat tttgctaaca aagaccaaca gcaatcgatc
     5521 ttaaagaatg tcttattgaa tgacactatc acacagatta ctactccata tttcaaattc
     5581 tatgaacaag atgctttatg caaactcgga cagacgaata tcgtctacca aacgattctt
     5641 gattattggg gagggatgtt atctcatgat gcggtaactt tctgggaaga atacgaccct
     5701 actcaaacag gaaatgaaaa gtacagtatg tatggagatc cttatggaaa aagcttatgc
     5761 catgcatggg gagcaagccc aatctatctt ttaggacgct attttatcgg tttgtatcca
     5821 acaaagccag gttatgaaga atttatgata caacctaatc tagattcatt tgaaacactg
     5881 aattgtacgc tacctatcaa agatggaaag atttcgcttg aaaaaacaaa agataagatc
     5941 gtgattactt ctgatagaac aggcggaaca gtgaaaatga atggtaaaag ttatcctctt
     6001 ctagcaaaac agccacttgt cttaacaagc tattcaaaaa taaatgcata aaacaaaaaa
     6061 ctgcttgcga catatcagaa gactttaaat cttcttctga tattgtccaa gcaattttta
     6121 ttttgaagtt tgcttaattc tgttctttag aaacaatgtt tgttcttttt ccggcaaaaa
     6181 gaaagctaga taatacgaca agtaaaaaga aagcgatgat tccaactgtc aaggctattt
     6241 gaccgtattc tcctagtttc ccaagtacaa gtcctggtac tagataatca gtatcggcaa
     6301 atgtagaaga agcgatttta agatctccta atactggaag gataaataat ggcagccaac
     6361 taatcaataa gctattgaaa gcagaaccta ataccgcccc tcttctaccg ccagtcgagt
     6421 tgccgaagac accagaagca gctccgcaga agaaatgtcc tactacccca ggaatgataa
     6481 ctgtagtttg caagcctatc atagcaaaca tggatagtgt tcctacaaag aagctaacaa
     6541 aaaagccaat taatacagca ttaggtgcat atggaaaaac gataggaaca tctaatgctg
     6601 gtttagaatc gggtacgagt tttttagcaa tcccttggaa tgctggaacg atttctgcca
     6661 acaccattcg aaccccttga aggacgataa caaacccagc tgtgaatgtt ccagcttgga
     6721 tcagtgcaaa gattacagcg ttgtctccat tgcttagttc tctttcaaca aatccaggac
     6781 cagctaacaa agcaagtgcg acatatacga tcgacatcaa gagcatgatc gatacagtag
     6841 aatctcgcaa aaagctgaaa cttttaggaa tctttatgtc ctctgtagaa cggtctttgt
     6901 ttccaaaaaa ctttccgatc catccactag aagcataacc gatatttccg gtatgcccta
     6961 acgcaacttg attgtttcca gtgatgttct tcataaacgg ttgacaaaga gcaggcgtaa
     7021 tagttaatag tgttccttcg aagaccccgc ctaataagat catccacaaa tttgcagtaa
     7081 accccgcgct tactaaaatg actgctgtta gacaagaaac ataaagcatt gcttgacctg
     7141 taagaaaaat gaatttatat cttgtgaatc tagcaagtaa aatattcacg atcatcccta
     7201 ctagcatgat caaagcagta ggtgtaccgt attgttgcaa agcaatcgcc actactgctt
     7261 cattgctagg aactactcct tgagtatgca gagctgtttg gaacatcgaa gcaaaagggg
     7321 ttagtgaatt actgattaaa ccagcaccgc cgatcagtac taggaatccg acaaatgttt
     7381 tgatagttcc ttggatcact tctgaaaatt tcttcttctg aagaacgaga ccaagcagtg
     7441 caatcaaaga aacgaggatg gagggctgac tgacgattga cacaaacaaa ttcaacaatt
     7501 tatccattga tagttcctcc cttgaatcat ttttattctt ttgacaagat cttcgttact
     7561 ttttctttta cttcttcgct gtcaatgatc gattgcaaag gtacgagctt ttcatcaggt
     7621 atagaagtta gcgtatcttt caaagaatgc tcaatgaaga aataatcagc catatcgcta
     7681 gatacacttc caacatccgt atgacttact tcaaactcgt ccacatctgc tccaagatct
     7741 gcaagtgctt gtttgatgtt catctctacc ataaaacttg ttcctaatcc actttgacat
     7801 actgcaaaaa ttttcatatc attcgtctcc ttttcttatg atcgctaata tttcttcttt
     7861 tgttgatgcg tgtaataaat cttgaagatt ttgtttatta gaaagtagct ttgttaaatt
     7921 tgccaaagcc cgaagatgtg cctcattatc gatagcagct aaacagatga acaaactaat
     7981 gggatgggct ggattatcaa gcagatccac aggttgttga agtttcagca aagacatccc
     8041 tacttcgttt acgccatctt ctggacgagc atgaggtaat gcgatgtgat cgccaatatg
     8101 gataaacgca ccatactgct ccacgcgctc gatcatagct ttgatataac tttcttctat
     8161 tttattttct gataatagcg gctgtgcggc aaatgtgatt gcttcttgcc agttttttgg
     8221 ttgatccgat aattggatca tttcttctgt taataattca gatagcatag gacgttgatc
     8281 ctccttcttt tctaaaagtt tgttcatttt acgatttaat acttgataga gcttttcttc
     8341 gtctacgcct tcttttaatt cgatataagg cagtagcgcc gacaacaatt cttgggcaga
     8401 aggcattgaa aatcctggta tcagccaatc tctttgtact tgattgatca gctgattttt
     8461 ttccaagtca gtcatgattg gatgcagaac atagagagac tttttcttat cagtaagtgt
     8521 gagaggtaca gtagaaaaaa taatatcgta agaagtttcg tcaacctcgt gtaagcggtc
     8581 agctgaatta gtctctgtaa aaaagatcat cgggaataat tgctgaagtt cactttttaa
     8641 gatcaatgaa gagctaatgc cacttggaca gacgatcacg gctcttattt ttctatttct
     8701 ttcttctgcg tccgcttttc tgatctctcc gccaaatagt atagtgaaaa aaccaatctc
     8761 ttcttcaggg atgctcttcc ctattcgtct ttctaacgga agtaatgctt ttcttgtcat
     8821 ttcgtagatg gaagcatatt gatgcttaat ttgatcgatc atcacattag gtaaataaaa
     8881 agaataggaa atacgaaaat aggcagggac caagtgataa aagacattca tcaataattc
     8941 acgaaacgaa gcaaattcta cggccatcag gaattccatg cgatggatga cttctgaaga
     9001 acattccagc aaaaaatcaa gtgcaggctc ctggacatct ccttcaacga tcgatgctaa
     9061 gcaaagagag aaaaatataa tctccgaatt ttgatgttcg gaatagccaa ggccagtcaa
     9121 tacttgtcga ctaatgtcag tgactgcaag agaagccaac agttcagcat cttttaccag
     9181 ttccatggat gtttttccaa ttcgaatggt tgtcaaactc aaataataag ctaattcatc
     9241 cattcgattt ggtgcgaatc gaagatctga tagtgaaatc gttttatcta gcaaatctct
     9301 aactttggcg taataatcaa tggaaagggt tgcggttaaa tacgtgagcc caaatcttcc
     9361 agcaagtgac tgcatcaaac gagcagtgcg attttttgct tctcttctta atattgcttc
     9421 tgaccctagc agcctaaaac cagttttcct agtatacgac agctgacaat cttccacttc
     9481 taattcattt cttatctttt tgatatctga caggactgtc cctttagaaa cctgaagaaa
     9541 atcttgaaaa tgaaaaacag aaacagacgt tgcagtcgaa taaaccatca aataaagaag
     9601 atctcttcgc tcttgttcgg tatacacagc ttcaaatcga gtaatatcca aaaatttttc
     9661 tgcccagtcg attgctcgga atttctttat acggatacgg gtatcatcca catattcggc
     9721 aaaaggagtt aattgtttga tcgcctcgct tgtatttact tcgatgatct ctgctgcttt
     9781 ttctagactg atttctcttg gtgttttcag gagataacta attttgtagt tcacagcgct
     9841 gttcacctcc tacttatatt ctagtatggt agcgctttta aatcgagggg tgtttggtac
     9901 aacttacagt tggatttttt ttacgactgt accgaacgat ttctatcgaa tggatacaga
     9961 aaaaaagcag gtgaccaaat gtctcctgct tttatgaatt gatttcgtcc gatcaatgat
    10021 gatcatgttt attttttgag gtcagttctt caaatttttc tttgacatct tcaaccgctt
    10081 tttcgatatc tttttcaaag tgattgggct cattaggctt tgtttcctct tctacagaat
    10141 ttgaaccaga taaagctgtt tctttatttt ctgtttcacc agagtttgtg ccagctaatg
    10201 attcttcttt gtcttctgtt tcaccagaat tagttcctgc taaagccact tcttcttctg
    10261 ttttaggggc cattgaacct cttaatcgtt tgtgtttttc accgtcataa tttgtcatgt
    10321 tggttcctcc tagtagttct atactttttc atcgtacaat aagacagttt atgcgtcaaa
    10381 aaacaaaccc gattcttaca aatatgtcat atttttcctt ctgattcttg aatgcttttg
    10441 attccttctt ccaaaatttt catttgtaag attgtttctt catctttgat gactttttct
    10501 gcgccattaa ctaatgtctc gtaaatccct tcgtagacac ggctgtaatc accaacctcg
    10561 gaaattactt tttcttcatg ataactccct tgttcatcta tataggtcaa tacaccataa
    10621 tgttcgggca aatcgatacc aaagtcttca tgatcaggca tgtaaaacat tttcagatgt
    10681 tcttcttgtc gatcttttgt ttgtttcacg aacatccctt tttttccgta aacgacgaaa
    10741 cttggacgtt ctttgatgcg gaaataactg gattttatcg aaattttcat atttccatag
    10801 aaaaaatcca gatcgaagta atcattcatt cgtcctttcc ctaaaagttg acgtacatca
    10861 tagctgatat catctggttc gccgaaataa gaaagaactt gatctactgt atgacaagca
    10921 tgtccatata aatagctgtt cgcagtagaa aattcatgcg tattttctgg tacttccggt
    10981 ctgaaataat cataatgcat ttctacttct aaaatatccc ctaattttcc gctttcgatt
    11041 actttttgga ctgtcaagaa gtcagaatcg aaccgtctgt tttggtaaca ttggataaat
    11101 agaccttttt cttttgctaa tgcaaataac tcttctgctt cctttgacgt ttctgcaaaa
    11161 ggtttctcta ctagtacatt cttaccatgt tcgagtgcca tttttccata ttcataatga
    11221 aattgactag gtgtagtgat gacaactaat tggatctcag gatcatccca aagatcagac
    11281 agctgatcag tatattcgat gtcttcgaat gttttccaca ctggttcaga tggggaaaaa
    11341 atttttttga tattgatttt gttcgtaagt tttcttgaaa aaggcaaatg atagcgattt
    11401 gtactctttc cattgccaag ataagcgatt gtaagcatga gtggtgcctc cttttattga
    11461 tgttttcagt atatcctaga aaagcgcaga aagtatttat aatagctatt ctggtaaaaa
    11521 agttcagaaa aacacttgtt atcattcggt ttggtgaaat taatgttcaa agtaaggata
    11581 aaaatcaaaa agatagtagc ggaaccaagt gtttatcagt aagatagaat ttggaggtca
    11641 gatcatgctt attgaagaaa aactaacaaa acaagagttg tttaccacga cagagaaacg
    11701 gattgtcgat tacatccgta ggaatatcga agctgcagtc tacatgacga ttgaagaatt
    11761 agcaaaagct acgtatactt cccattcagc tatcattcgt ttatgcaaaa aaatgggatt
    11821 cagcggattt aaagaattcc gtttcgagct ggggcgggaa gttcatcaat tgattgctca
    11881 gttcaatcaa acgattgatc ctaattttcc tttttcaagt gaagatagca ctcagcaaat
    11941 tgcaaagaaa atggcggatt tatcgatcca gtcaataaaa aaagcacaat tgcagattga
    12001 acatgaagat ttagatcaaa tcggtaaagt attgaacaag gcacagcgaa tctttctttt
    12061 tgcaaaaggt gattctcaaa tcacggcaag gaaattccag aataaaatgg tcaagttgaa
    12121 taagtttttg atcatggctg aagaatacag tgattcttct tggaatgcag ccaatttgac
    12181 tagcgaggat tgcgccattt ttattagcta cagcggtcgc atccatcatt atgaacgaat
    12241 aatgacctat ttgaagcatg tagaggcccc taccttgctg attaccggaa atcagcattc
    12301 agaaatggcc aaacaggctg atatgtgtct tgttatatcg caggaggaat atgattttgc
    12361 taaagtagcg actttctcct ctcaaattgc cttcgattac gtattaaata cgttattctc
    12421 agtgatatat tctcaaaatt ttgaagagaa tatccgcaac ttgaaaaaca aacaagaatt
    12481 gatgcaaaaa ggccttctta aagaatatcg gaaaacttaa gaaaagatcc tcatttagta
    12541 ataagaaaga tagtgtttga taggctctct ttgatatcat cataaaaaca ggctgaagtt
    12601 ttctttttca aacctcagcc tgtttgttta cggaacgatt cgaatagata tattatagaa
    12661 atgaggaata gctaacttct gtttcttatt ttgaacgatt gacgaaaaag atatataaga
    12721 aggaggaaaa tcagtataca tgcagctaac aatccataca ggaaaaatcg tttgttctcg
    12781 gatactttct gtacttcttt ttgaacttct tttgcatgat aaggaacccg gtgccctctg
    12841 acaagtaagc gatgactgtt gaccatataa ggtgtacaag ttaggagtgt cacgaaatcc
    12901 tgcccttttt cgattctcag atcttttgta tcagtcggtt ctaccgtctt gatctgatcg
    12961 acttgataag cgagtgtccg tccattgatt tcgatataga aagaatcacc taaagtcagt
    13021 ttcggtaagt ctgtgaacaa ctttgcttga ggcagtcctc gatggctgga aataacggca
    13081 tgtgtatttt ctccccccgt aggataagac gttccttcca ataatgaggc acctttttct
    13141 agcagcacag tattcgtttc atcaaaaatt ggcaaatgga cattgatctc agggatcgtc
    13201 aaaataccga tcgtatgttt ctcaaaatag gttctatcct ttttcgcagg ttcttttttc
    13261 ttagtaaagg gatctgcacc tggatttcca ccttcttttg ctaattgctg gtttttcttt
    13321 gtcatgtttt cttggatttt agccatgact tcttcatttt ctttgaccgc ttgttgctga
    13381 taatgagaga tgatctgctg atccagataa ttattcagcg cgtcgctaac aaatggataa
    13441 gctagtatcc ctattcctga gagaagcaag aaaagcatca gcagatctag aagtttcctt
    13501 ttctttggtt tcatttgtgt tctccttgtg atgactgttt gataataaaa gaaaaaggag
    13561 catttgcgta atccgctgct cctttttcca attcttgcaa aaagactaaa tctgactgtg
    13621 cttgcgtcta gcaaagtaca gtccagcaat cagtagaagg actactcctg caccgatata
    13681 cacatagatt cccttaccgc ctgttgaagg aagtgtacct ttgtgtttat ttggtatttt
    13741 ttcaggagaa atcaactgtc ctgctgttac ataagattgt tcatcgatag taaatgctac
    13801 acggtttgtt aatggaacat atttttctgg cgctttcgtt tcttccagat agtacgtgcc
    13861 atattttaga cctgtcacat cgattaaacc gttacttgtg gttgtaaaaa ccgttgctga
    13921 ttctttcgcc gatacccagc tgacggcttt tgtggatggg tcgatcgata aatatttcgc
    13981 tgtgtcacta tcttgatcac gaacgacgaa ttctgctcca gcaagtgttt ggtctgatgt
    14041 aacgtcacca tctactttaa caaatcgttt gcccccagta acgacatcga ctgacggtgg
    14101 tgtttgatca tttgtatgcc cgttatcgac atttgcttgg ttagaaaatc ctttggttgg
    14161 atctgctttt tcgttcaaat gcatatagta aacgaatttc aatgtaccgc caggagttaa
    14221 tgaaggaata taattcggat caactgaaac cgtgaatccg tctgtttgct cagtgacaga
    14281 ataatttact gggtcgattt ctttatttcc atcatataag gcataagcat acgttcctga
    14341 agaatcatta tcaaatgtta aagcagcgtc atgagtatcg ataagtttga atgttgtgta
    14401 cttgttttgc gttccttctt tatcagcgat acctaatggg atattgacag aaatctcata
    14461 ttgaattttt tcaccgattg cgacatcttt tccattcaat tgaggtgttg ttttatcaac
    14521 tttagacgta tcatttttga tggtcttttc tactggtgtt tggctatttg ccaggatctc
    14581 aaaaggcgtg attgtttgct tttcaatcat ttccgcatta tcaggagctt ttacttcttc
    14641 taaattatat tttccaactt ctaaatgatt aacgatcaac tggccttttt caatagatgc
    14701 ctcggcaaag tcattgttgc cgatgtcata agaatgacca gtaatgaaat gtttggcttt
    14761 ggtttgatca gttgtccaag tgtacaatcc atctgtgaca ctttggatgt attttttgac
    14821 gcttggtgtt ccttcttctt tagaaataat aaattctgct ccatttagtg cttcgttttc
    14881 ggcagtaccg atttttgtaa ctttcaacgt tccatcatta ccgactgtat ttttagggta
    14941 gagatggata gtatctagtt cttctgtccc gtatttataa gagccatctg cttgtttgat
    15001 catctcatat acagggaaag ctaaaaccat gtttgcggca gctgacactc cgtcttttgg
    15061 ttcttctttg atcgtgtaga ctgcatcttt cccattttgt tttttaggta aagataaagt
    15121 gacatttcca tcagcatctg tcgttcctga agcaactggt gtaccaggag tcaaagactg
    15181 gactgcttgt tttgctgcat ccacggacgc tcctttatct cgttgcgcat aaaattcttg
    15241 agtgacgtta taaactgaaa atgaaatatc ggctaatcct tggtattgat cgaattcgct
    15301 catttctttc ccgctgtttt ggattaaagg atcgggtaaa tcagtcattt tctttttatg
    15361 aaggatgact tgagctgctg tctcctctgc aaacactttt tttgcgccga agctgtttgt
    15421 gagtaatggt aaaataagga aaaggactcc taacataacg tttatttttt tatgattttt
    15481 cattttttca ctcctgttct ttttttgata aacaaccaga ttgcaaagct tgcgaatacc
    15541 ataccaacaa cgcctaaaag tgtatttttc gtttcgtttg tttttggaag aaatggacgg
    15601 ctattttctt ttttattgac tactttcaat atactgtccg cctctttatc ctcagaaaga
    15661 aaagttgaaa tggtaaacgg aatttctgtt tcacttaaaa tataaccaga aggtgcttcg
    15721 atctctttta atcgataact tcctgttttc aacccggaaa ttgaaaaagc gccattttta
    15781 tcggaaatca ggtgaagcgc atctgattcg ttctttgtcc acttgtatcc gttggctgtt
    15841 tgctggaggt aatttcctgc tttgttttta ataaggaata ctgcgccagc taatcgttta
    15901 tctggtttat ttgtctcgat tttgacaaat tgcttactcc ctgtatatac agagactttc
    15961 tttgtactga caccaaaacc aaaatccagt gttccgttgt tgttgatttc cttgttcgcc
    16021 tgtgctgtac tgcttagctg catctgataa gaaatggtca gtttttttcc agcatatttt
    16081 tccaacgaag ggatcgaaaa taaaacatca aatccgtgag gtttcttgtg tatgacaaag
    16141 ccttctgtca gcttttctcc attcgatgaa atcgttaaac tattaggtaa aaacgttaat
    16201 gcttcatccg cactatctga caattcgaac ttttgatagt caaggatatt tacaggaatt
    16261 gtcgtatgca aggaataagt gattttttca ccaatcgtaa aatcatttct aggctcttct
    16321 aataccttct caaaaggtgg atcagggtag tcgttttctt catttttagg atacaaatgg
    16381 atagttgaaa gtttttgatt gttttgtcca tgtacaggaa gaacaactac catattctct
    16441 gccttttctt tgacgacttc tggtactttg gattcaatga aaagatacgc tttatctctt
    16501 ttttcttgat ctttagcggc cagagaaaaa gaagcgatac catcttcgtt gttaagagtt
    16561 gtagttgttg cttctgcggt aaacataccg gaagacgcac cgttttttgc gatctctgct
    16621 tgtgcttctt ctaccgtttt gcccttttcc cgtagatggt aaaaagaatc tgtgacatca
    16681 taaacttgga atgtgacacc atttaatcct cgatacgttt gtaataaagc tttttcttgt
    16741 ccgtcatttg gatgattttt cggcagttgc ccgtttggga aaagcaattt gtgtaaagta
    16801 atctgaacca tttctgtttc tgtttctgtt gctacctgag taaaagctgg tttaaatagt
    16861 aacaagaaga gacacatact aagccaacca agttttttca tatttagctg ccccctcttt
    16921 cttttttcaa aaaaagatac caaatagaaa acgcacaacc aatcatccct actagataga
    16981 ttcctaaacg gccaattcct cccgtttcag gtaatggtac ttttgcctga ttcgtgatgt
    17041 ctaaagaaat ctggttgttt ttggctcctg gtgacagaac agattcatga tcttgtccat
    17101 ccacttgaat tgacccatct tcgtgtataa ctatagtaac tggctctttt agaccttggt
    17161 atccttctgg tgtaaaagtt tcggtcagcg tataagttcc aggttttaaa ttttcgaata
    17221 gaaaggtatc tgtttcttgt ccatcttttg gcgattctaa gtccatttct ggtccctgca
    17281 gtctgaattt tgctcctttt aatgtctgtc cgttgtcttc ttttttgtgt accgttagat
    17341 caaacgcttt tagtcgattt tgatgagtga gcgtccatac attatttgtc atctcggtat
    17401 tttttcccgt gtaaatgatt tttccatatt tatcgatttg gaattcataa tttcccggcg
    17461 aagtatcata tccggcagga ccagctgttt caacgactcg atatttacca ggtgtgagtg
    17521 aatcaaaact ggcaagacct ttttcattcg ttgtttggct gtcaattggc tgataagtac
    17581 catttgcttc ttttttctgt agggaaaatg ctgctccttt aagatttatc tctttgtccg
    17641 tcccttgcat cgcatactta cgtactgcta caggaacttc aacaaaagga ttttcaatag
    17701 tcaactggat cgtatcatcg gaagtagtga ctgtttttcc atcaatggtt accgtaccat
    17761 cagaagcgat cttgatttcc caagtagtct ttttgcttaa tccatgccct tctggagctt
    17821 ttgtttctgt cagcgtatag gtcatttctt tttgcaattt gacattttct ggaagagaat
    17881 aggttccgtc gccatgatct gttagtaaag tatcaataga atctcctgtt aatttgaaaa
    17941 cagcgccaat aagatccttt tcacctgtag aggaattttt cgttattttc aagtttaacg
    18001 gtgtgaattg tttagtattt ttccatgtca ttgcatctat ttgttgagaa tcgtatcctg
    18061 gtacaggtaa ttctttgatt gtttggtaac tgaatgcttg accttgatta ttgtattgag
    18121 gtagtgataa tatctcttga taactttctc cgctatttgc agataatttg tcaatgtctg
    18181 cacgttccca cgtatttgtt gtatctttag ctggtttaat gattcgaata tatccgtttt
    18241 tccaagctgc agcatttgtc gtatgttccc gttgaatctc aaaagtaact tgatctggac
    18301 gatcagctag attgttgtca aattcttccc ataacttttt gatgtgaaga ctgactccgg
    18361 gagctttagc agatggtata ccgaattcag ctaattcatt ggtatcaatg tttggctgga
    18421 aagttgtcct gccgttcatt tgataccaga aatttggatg gaagtcctca ttttctgttt
    18481 ggattctcac ttggtaatgg atttggattt cttggtcttt tcctaaatag atctgattgc
    18541 tcttgatggt atttccttct atggaaatag atggagtgac cgttgtagga cttgtcccca
    18601 cactcttgac tgaaagtgta ccaggctgat aaatgaatgg ttctgcgatt ggatcattta
    18661 tttgtccatt gcttacagtt gctgagatct gtacagcttt tttggctagg tattcagaga
    18721 tatctgttgc atgatcagct gattcatagt aaagatcgcc tttttcatct gatgaaacca
    18781 tttgtcgcat acgagactct acttctgctt ttgagagacc agctgccgga tcgctttgaa
    18841 gttggatgcc aagaccatgt atttcgattc ctcgttcttt gagtgccatc gcttctccga
    18901 tggttgcgat aaacgtactg tcgattcttc tggatagatt gttttggtca ggtgcatcat
    18961 agattcttga gattagagaa gtatttcccg gccgatcttg cgtattagaa aactgagttc
    19021 cgtaataatt gctgcttgat tgtgcgtgta cccgctgtac tttataggaa aatgttggta
    19081 caccatccgt cagcaaaacg atcacttttt tatgtccatt tggaacggat agcatgcttc
    19141 ctgcatctct tagtgctttt tgtgtaaaag taccaccatt tgtccgtgaa ggtgtaatgg
    19201 attttacttg atttttcact gaatcaaatg aacccatctg tactgcaccg ttactgtagc
    19261 tatatccttc gcttgagtag ccgacatatc ccatattgat tttgtctgtg ataccgctat
    19321 ctgctaaagt atcgacaaaa cgatcgacac caatctttac ttcaccgatc cgattattgt
    19381 cgttcatact tcctgaccag tctacgacca atacgagatc aagaggcgtg atatcttttt
    19441 gtacatttcc acgagcattc aaataaacat caaacaatcc gggtgtactt gtttcctttg
    19501 catactttcg tatcgcatag tctgcttgat taccggttcc tccatattcg atatacgaat
    19561 gggtccgatc attaggatct ccattccaag aatttatacc atcccattga tttgttccgt
    19621 ttttattgcc ttgatgatca agaacatttg tatttcctgt aggttgccaa ctggctttag
    19681 gataagtgcc ctgatcatct gttgtatatt ctgtaggaat cgtttgatta gatggcacac
    19741 tcacagctgg caaggataat gtaggcaatg taaatgggct gacagaattt tcgttttctt
    19801 ttgatgattc ttcttctatt tcgtctggct ttggtactga cacatctgta tctttcttat
    19861 tttctgtctc atcaataatg tcatattctt tattatcgac gatcagcttg tttgcctggc
    19921 tgtggtaaag tgctggatcg attggaaaac tcagatcgat agtttgttta gtgtttgatg
    19981 agatttccaa cgtaattttc ccgctattta cctgataagc atagccatct ccttcttttc
    20041 tttccacatc acttaagtaa ttttcgacta gaccaatttc tttttctatc ttttcagcac
    20101 tggtgttatt cgcatttagc ttgatgttca gtgctttttt tccagactga tccgaaatga
    20161 cttcagctga aattgtttct aaaactgttg gatcatctgt agtgtctgct attgcagata
    20221 atggcacaaa gtttgataaa ctcaatatta tcagcatgaa aataactttc agtttcttcc
    20281 ctgtggtcgt catttttccc ctcctttttc tttttttctg ttttgacgtg aatagtgaaa
    20341 attattaaaa taaacaggcg ttacataatt ttatttattt taatatgata attattatac
    20401 gaagggcgct aaagggaatc acaccaattt tcataccaat tggtttcatt tatgaagttg
    20461 attccttcga ttaatgagcg tttcattgaa agaaaagggt tgagggagaa aaacatatga
    20521 tcaggttgtt ggaaggaaac tatagaaaga tggaaaaaat cattcgaatt ctgtccattt
    20581 ctgacaagtg gatgactaaa aaagaacttg ccaaacgaat tggtagttca gaatctacat
    20641 ttgtaaggta tatcgaagag atcaaaatcc gctggggaac ggatgtaacg attcaatctt
    20701 cacaaaaatt ggggtatcgt cttgaacatt tgaatgtacc agcttattta aatgttctga
    20761 tggaaatgtc gcaaagttct acaaacagtc gtttattaaa tgagattatt gtcaatccgg
    20821 gtaaaacgat tgagtattat tgtgaaaaaa tttccatcag ccggtcttct tttacacgta
    20881 agttgaaaca atgcaatcaa attttagaaa gctatttatt aaaagtgatc gttgaccaag
    20941 gttttcagtt aactagcctt aaaagtgagc tccagttgcg tatctttgtt acctttttct
    21001 ttttaagtta ctacggaaga cgcacgttgc catttccaat cgaaaaaaag aagatcaaag
    21061 aaattatggt caagaataat tgtcagatga atttgtttca ggaagaaagc ccatatgagc
    21121 aatctttctt tattatgtat tttgttgtgc atctcatgag agaatcccaa ggaactccat
    21181 ttgaatggaa agctggagac tcttatgtac agttgataaa tatcgataaa aaagacttct
    21241 taatcttgaa aaatctctta ggaaaattga agtacagcag ctatataaaa gtagtgaact
    21301 attttgtcaa tacgattttt tcagaatttt cggagaaaga aaaaaatgaa atcagtgagc
    21361 agatacgaaa aaatatgtcc tactgttcgt tttcatccgc tgattgcaaa gaaaaaaacg
    21421 aagaatatgt tgttcaatta ttaacgcaaa tttatttttt ctcccgtatt ttcccatacg
    21481 atacgactca tttgacgatc cgtgcaactt actttgcaca gcagatgcaa caccgccaga
    21541 tacgtctata tgctggattt cgtgcagaac ttcaatttta ttccactcta ctgaatcaga
    21601 atctgattta ttatttatct agctatatct tttggatgct tatcggtaat cctgaaattc
    21661 accattatac ttctgataaa aaaatactga ttatcagcga cttaagtctt cgacatagtc
    21721 aatatattga agaatatatc agtgatattc ttgctgtgca taaaattcac tctgagacaa
    21781 ctgctattac tgaagatcag ctgtcgaaat acaatcttct cgagtatgat ctgatcgtta
    21841 cgaatcaacc cattttgaat gcccatgttc ctcatatatt gattgatgat agtgtgtcat
    21901 tcgcaaatga agaagaactc atccgcttat tcgagttatg aataatcaaa aaacagctat
    21961 gtataaacca ccctgataaa aatttcagga caaatacaca tagctgtttc tttttattgt
    22021 attccttcag caatccaacg agatttatag cgaaagtctt ttaacaactc ttcttttgtc
    22081 caattatttg caatgagatc cgtcaaagtg ttcattacga gggtcatgga aaagtatagg
    22141 aaactaactg cttcttccga cgattgaatg gagaaatgat tgattcttaa taattccagc
    22201 catttttcgt tcattggaga atcagccgat agttctctac gtttggttgt ctgctgatca
    22261 tttcgctggg ttaacaagta taacctttgc caatagatac tttcgtgatc taagtcgcag
    22321 caccactcta aatatttttc gatccccaaa aagaaatgtt gtttgttttc gctaatgaat
    22381 tttaagatat cttgatggac tatgtgagaa ctgcttttga tcgtatacaa ataagcatct
    22441 tccaaatctt gaaaatattt ataaaaagca ccgcgcgaca tccccatctt gtcaacgatt
    22501 tctgagactt tgacttggct gatgtgctgt gagcaaaata tctccagtaa taggtcatcg
    22561 attctctgtt tctttgcgtt cgataaattg aaaaaagttt cttttggcat ccacatctct
    22621 cctttatctc tgattatacg tggatagccc ttcattgtca tgaaggattc attccttctt
    22681 tttctcttct tctgtcaagt acccatcttc cattcgataa acgcgatcac tccattgaat
    22741 catacggaca tcatgagtaa ccataatagt cgctttttgt ttctcatgag cttctttaac
    22801 tagtaatttg acgacttcat atgcatgatc tgtatccaaa ctagctgttg gttcgtctgc
    22861 taagatcaag cttggctcat tatataaagc gcgagcaatt gccactctct gtctttctcc
    22921 accagaaagg tctttaggat aactattttt aagtgactgg atatctaaag attgcagcaa
    22981 ggaatcgatt tttgttgaat cttctttttt tgaagtaact tggtcaacta gttcaaattg
    23041 ttcctttacc gttaaaaaag gaatcaaatt agagctttgg agaataaatc ctatttcttt
    23101 aaagcgtaaa tctgctcgtt ttttttctgg aagctcagtt agtgagtgac cgttgatcac
    23161 tatttctccg gaagtcggtg tttgcaatcc tcctgaaatg gtaaggaaag tacttttacc
    23221 tgaaccagaa ggaccaatga tgctgacgaa ttctccttcc tttacataaa aatcaattgc
    23281 tttcaaagct gagacctttg tatgaccaga accaaatgtt ttggtaactt ttttcatcgt
    23341 taatattttt ttcattttta ttaacctcct attgctgtaa ttgggtctac tttggttatc
    23401 gtacgtatcg aaaacaatcc gcctagcatt gcgacaatga tcaaaatccc actatatagc
    23461 aaccattgtg accaaaaaac agcaaaaggc atcgcgcttg gtaaaatcag actagtcaaa
    23521 taagcaaaca aaagagcaag cagaacgcct accaccccaa caataaagga ctgtgctact
    23581 aaagatttag cgatgaagaa atttttgatc ccttgtgctt tcattactcc aaaaatagca
    23641 gtcttctgaa gtgtcatcac gtacatgaaa ataccgacca cggcagcaac cactaagaac
    23701 aaaaagtata tcatcgcatt taaggtcata ttttgggcag aatagccagg aatactttca
    23761 atgaatgtcc caatagttaa taactgtaga cccttcgatg ctttttcttt cgaaatttta
    23821 gctgaatcct ttattacgat cccattgatc ggctgttctt cttcagaagc aaacggctgt
    23881 tgtccatact tcaaagcagt ccacgtatct agggacgcat agatgacggg agaaactgtg
    23941 taataagttt caggaaagat accgacaatc gtcaaaggat cgtcgtaact gccaattttg
    24001 atcgtatctc caattttata gcctgaatca gccagatttt gagagatgat gatttcattc
    24061 tttgttttaa attcatgccc tttcgtgagt tttggtaata aaaatgcttc tttcgttgtg
    24121 ccgaaaactg taacattttc tttgtttttt cctttgattg ctccgctgta caatccgatt
    24181 ggtgctttct ctcctccttc aatgtatttc agatctcctc ttgttaattg tgaagctgca
    24241 aatacttgat ttgcatcctc cgacaaaaca atctcttgtg cgtcccaatc atcgattgct
    24301 tttttaaact cttctgaaag tccattcgct agtcctgaca acatgaatac gacatacgca
    24361 atcaagaaca taataccgac gatcaagcca tatcgtaatt tagaatagcg aatttctttg
    24421 atagctagaa acatttgttt ttcctcccta tgatagattg atagtgacaa aatgtcactt
    24481 gttgaatagt gtaactctaa agtgacaatt tgtcacttgt gttgtttttt tcttatcaat
    24541 aaattgtcta agacatcttt cgataaaacc ttaacatgag tcataaaaaa tttatttaag
    24601 ccttatttat gctttccatg ataaactaaa gtgaccaaat caatgaggtg ggaaaatgat
    24661 taaactatta gtagtagaag acgataaagt attatccaat aatataaaag aaatactcgc
    24721 tgcaatcggc gagataacac aagtttatga tggtagtgaa ggactgttcg agttggaaag
    24781 tggagtttat gatcttgcaa tcttggattt gatgatgccg gaaatgaatg gatatgaagt
    24841 gttagcaaaa atacggaaag aaaaaataca gactccagta ttgattttga ctgcaaaaga
    24901 tagtttggaa gataagattg aaggatttga acgaggtgca gatgattatc taacaaaacc
    24961 tttctatcga gaagaactga tcatgcgcgt gaaagcatta ttgaaacgct cgctaggtct
    25021 ctttgatgaa aatgttctga agtataagga tatcagttgt gatttaaaaa gcaatgaagt
    25081 cttgtataaa gaacaagttt tgcccataca aggaaaagag tttgaattgc tcgtttattt
    25141 tttacaaaat aagggaatca ttttgacaaa agagcagata tttgaccgga tctggggatt
    25201 tgattctgat acgacgatta cagttattga agtttatatg agcaacttac gaaaacatct
    25261 gcgaagtact ggattggata aagaaatcaa aaccttacgt aatgtcggtt atatactgca
    25321 aagggtgtga tgcaatgaat ggagatatta cacgaaagca acgtagtcgc ttttttgcga
    25381 caaatgtagc agcatttgct tttatctttt ttcttttggg attcattact ttacagatat
    25441 taaaccaatc tgcatacaga gaaacagatc tgtcattaga gaaaataaat tttgattctc
    25501 gaacagtaca attagagata caaagatatc agcaaggcga tcccttttta aacccgactc
    25561 aaacggaaca aaacagaaca aacatggaac agccattaat ggaaccatca aatgaccgtt
    25621 ttaacactca agtgatcttg tggtctaaaa atggtgagat attgaataaa gcagctattg
    25681 gtgggcgttt caaccaaatc aaagaattaa aaatggatac gaaaaatctg aataccatcc
    25741 aaaatattga attaaatgaa gacagtggct catctgccct ctctttccgt tcgattacga
    25801 aaaaagcgga gacgaatcaa gatggcgttg cctacatcca aattttagaa aatacaaatc
    25861 aaatcaagaa ttcattagcg acttttcgca cgattatgat tttgtgtatg attgtttttt
    25921 ggattctctc tattggtatc agttattact tgtctagtct aagcatgcgc cctattattc
    25981 tttcttggag aagacaaaaa gaatttgttg agaatgcttc tcatgaattg cgcacaccgt
    26041 taacgattat tcaaaatagt ttggaacatc tttttaccaa gcctaatcat actattattg
    26101 aagaatccga aagcatcgct caagcattgt cagagacgag gcgcctcact ggattgactt
    26161 cggatttgct gacaatcgct cggaatgatt ctgatcagca gctgctttca aagcaaatga
    26221 tcaatacaca agaatatatc gaacaacttg ttaaaccatt tcaagagatg gccatcatag
    26281 atggaaaaga gtttattctc cataacgatg caacattaga agtaccaatt gatgaaaaaa
    26341 aaatccatca agttttggtt attttgctgg ataatgcatt aaaatatacg aatccagaag
    26401 ataagatcat tttggattca tctgttaacc ataaagaatg gctgattcac gtaaagaata
    26461 ctggcccttc tatcagtgaa gaagatcaag caaggatttt tgatcgattt tatcgggaag
    26521 atcaatctcg ggcgaaagag actggcggat acgggcttgg cttggcaatt gcaaaacagg
    26581 taatcgaaca gcatcatgga cagatttctg tatccaatta tcttccacaa ggagtcgatt
    26641 ttaaagtcca attgccgttg aagcctaaaa aataatgctt atccctaaaa aagggctgtg
    26701 acaaaaatct tgtcacagcc cttttttgtt gcgaataaac ggtgttccag aagtagcttc
    26761 ttcggaaata agccgaaatt tctttaagct gaccacttct gtcacaacct ctttagctta
    26821 cgcttacgat tttttattgc ggtcttcaat gtgtacatca ccgcttgtgt caatatccaa
    26881 ttcttctcgg ctaacatctt ctgtcacttt ttcaacatct tcatgttctt ctttatgaat
    26941 cccaacttct tcacgaataa ctgtatgttt gcttacatct acttgctctt ctttgattgg
    27001 gatagtaatc gtgtcatctt ccaatttttc gtctgttccc tgtgaagatt gatctgttac
    27061 tggtttgcgt tcgatgacga tttcttcacg tttgaccggt acttctaccg tttcagtatc
    27121 gttgaccaca tgtttgtgga tgtcgacttc tccagttgtc acatcatgtg tatttacatc
    27181 taatttttct tcttttagtt gaattgtatc atcatctaga tttggtttgc gatcgatgtc
    27241 ttcagtcttg cttgtaccca ttgtatcagt ctcgccaggt acgtccatcg gatcagttcc
    27301 tggtgtcata ttcaatggat ccgttgtatt ttgaaagcct gtcgtgccac ctacgtccat
    27361 tggatctgtt ccagtgccag tttctaatcc agtccccatt gtgcttgctg ggctaacagt
    27421 atcttgtgta tccattgtat cttctgttgt ttctggctga cgatagcctt ttactgtgat
    27481 gacaaatttt ccatcagaaa tatctcctct atattgatat aaaggatcat tttctggtgt
    27541 agccgtctca gaatcatagg tatcaaaaga aaaagtatct tttatttttt cccataaaga
    27601 acggtcttct tcaccatcca tccgattttc atctgtttca acatctatac cagacaatcc
    27661 gtcaaatcct agtctagatg ctgcttcatc agtagtataa ataacgatat catctcgttc
    27721 atacccttcg ttacgcaacc gttcaattac tgataatgct tcttccctcg tactatagct
    27781 tccgatgacc gttaaatttt tctcttccat gtaaattcct cctagcaaat agatttatga
    27841 ttggtatatt gttacttata aatttattct ataggagacg attgttttct acaaatattt
    27901 agattggaat ttgattaaaa caatttaatt gaaatttgaa aacatttatg ttaatgaaag
    27961 tc
//
LOCUS       DAZKCH010000033        27499 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000033 DAZKCH010000000
VERSION     DAZKCH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.033"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            277..1446
                     /locus_tag="ACG84X_001415"
     CDS             277..1446
                     /locus_tag="ACG84X_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFP9127296.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            1919..2473
                     /locus_tag="ACG84X_001416"
     CDS             1919..2473
                     /locus_tag="ACG84X_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9127297.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(2646..3083)
                     /locus_tag="ACG84X_001417"
     CDS             complement(2646..3083)
                     /locus_tag="ACG84X_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9127298.1"
                     /translation="MFSSEENKPLYLDYVNHNLKIIIKENNLKHITLHGFRHTHCSLL
                     FESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFMSSTEEKQGSLQK
                     VKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            3131..4078
                     /locus_tag="ACG84X_001418"
                     /pseudo
     CDS             3131..4078
                     /locus_tag="ACG84X_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            4349..4784
                     /locus_tag="ACG84X_001419"
                     /pseudo
     CDS             4349..4784
                     /locus_tag="ACG84X_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            4800..5633
                     /locus_tag="ACG84X_001420"
     CDS             4800..5633
                     /locus_tag="ACG84X_001420"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9127299.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            5878..6903
                     /locus_tag="ACG84X_001421"
     CDS             5878..6903
                     /locus_tag="ACG84X_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9127300.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            7041..7166
                     /locus_tag="ACG84X_001422"
     CDS             7041..7166
                     /locus_tag="ACG84X_001422"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127301.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            7191..8306
                     /locus_tag="ACG84X_001423"
                     /pseudo
     CDS             7191..8306
                     /locus_tag="ACG84X_001423"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            8389..9285
                     /locus_tag="ACG84X_001424"
                     /pseudo
     CDS             8389..9285
                     /locus_tag="ACG84X_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            9301..10125
                     /locus_tag="ACG84X_001425"
     CDS             9301..10125
                     /locus_tag="ACG84X_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127302.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            10157..11467
                     /locus_tag="ACG84X_001426"
     CDS             10157..11467
                     /locus_tag="ACG84X_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HFP9127303.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            11615..12874
                     /locus_tag="ACG84X_001427"
     CDS             11615..12874
                     /locus_tag="ACG84X_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFP9127304.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            12884..13756
                     /locus_tag="ACG84X_001428"
     CDS             12884..13756
                     /locus_tag="ACG84X_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127305.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            13768..14598
                     /locus_tag="ACG84X_001429"
     CDS             13768..14598
                     /locus_tag="ACG84X_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127306.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            14638..16821
                     /locus_tag="ACG84X_001430"
     CDS             14638..16821
                     /locus_tag="ACG84X_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFP9127307.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            16882..18102
                     /locus_tag="ACG84X_001431"
     CDS             16882..18102
                     /locus_tag="ACG84X_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFP9127308.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            18099..19559
                     /gene="gtfA"
                     /locus_tag="ACG84X_001432"
     CDS             18099..19559
                     /gene="gtfA"
                     /locus_tag="ACG84X_001432"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HFP9127309.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            19636..20742
                     /locus_tag="ACG84X_001433"
                     /pseudo
     CDS             19636..20742
                     /locus_tag="ACG84X_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            21064..21273
                     /locus_tag="ACG84X_001434"
     CDS             21064..21273
                     /locus_tag="ACG84X_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFP9127310.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            21266..21415
                     /locus_tag="ACG84X_001435"
     CDS             21266..21415
                     /locus_tag="ACG84X_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFP9127311.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            21569..22234
                     /locus_tag="ACG84X_001436"
     CDS             21569..22234
                     /locus_tag="ACG84X_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9127312.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(22518..23603)
                     /gene="xerS"
                     /locus_tag="ACG84X_001437"
     CDS             complement(22518..23603)
                     /gene="xerS"
                     /locus_tag="ACG84X_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFP9127313.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            23937..24170
                     /locus_tag="ACG84X_001438"
     CDS             23937..24170
                     /locus_tag="ACG84X_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HFP9127314.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            24167..24574
                     /locus_tag="ACG84X_001439"
     CDS             24167..24574
                     /locus_tag="ACG84X_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFP9127315.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(25711..26229)
                     /locus_tag="ACG84X_001440"
     CDS             complement(25711..26229)
                     /locus_tag="ACG84X_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFP9127316.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            26596..26844
                     /locus_tag="ACG84X_001441"
     CDS             26596..26844
                     /locus_tag="ACG84X_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127317.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
     gene            27347..>27499
                     /locus_tag="ACG84X_001442"
     CDS             27347..>27499
                     /locus_tag="ACG84X_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9127318.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTS"
BASE COUNT         9418 a         4176 c         5082 g         8823 t
ORIGIN      
        1 atttgttggt agtataattt aaaggtaata agttattctt ttattactat gtttgggttt
       61 tatagcaaag aaagtttaat aagagtttgg acctagcaaa caatattaat gaggtcatta
      121 aatcttatta tctttagtga tataacgaaa tatctacaca gacaaaatga tagcgtaaaa
      181 tattttgtgt aaatagatat ttagggtaga aaaaaagaaa gtccattctg taaaattaaa
      241 gttaccacaa ccgaaatttt ataggaggac tttctcatgc ccaattttac tacagaaatt
      301 atggaaacac taatcaataa aggtgattta gatgaattat ttcgatgtca tttagaatta
      361 gctgttaatt cattattgca ggctgaatta acagcttttc ttgattatga aaaatatgat
      421 cgtgctgggt tcaattcagg taattcccgt aatgggaatt attcacgttc attcagaaca
      481 gagtatggag aattaaattt ggtaattcct agagatagaa atggtaagtt ttctcaacaa
      541 actttacctg cttataaaag aaccaatgac tctttagaaa ccactattat tcagctattt
      601 caaaaaggaa ttactatgtc tgaaatctct gaattgattg aaaaaatgta cgggcatcac
      661 tatacgccac aaaccatttc aaatatgact aaaatagttt ctgaagatat tattgccttt
      721 aaagaaaggt ccttagaatc cagatactct gtcattttta tggatgctac tcacattcct
      781 ttaaaaagac aaactgtttc aaaagaagca gtttatattg taattggcat tcgattagat
      841 ggaaccaaag aggttcttgg gtttagtctt gctccaactg aatctgctta tgtttggaaa
      901 gagattcttc aagacctaaa agaccgtggt ttaaaagagg ttttattagt cgtaactgat
      961 ggtttaagtg gcattaacga tagtattcat agtgtttatc caaatgctca atttcaacaa
     1021 tgttgtgtcc atatatctag aaatatcgct cataaggttc gtgttagtga tcgacaagaa
     1081 atctgtagcg atttcaaatt agtttatcaa gcaagttcaa aagaagaagc aaataatcaa
     1141 ataaggttta tgatagataa atggaaaaag cagtatccac gagtggttaa attgctcatg
     1201 aatcctgcta tattaacctt ttataatttc cctccgtcaa tcagaagaac tatttattca
     1261 actaatttga ttgaaggttt taacaaacaa ttaaagaaat ataccaaaag aaaagagcaa
     1321 tttcctaatg aagaatctct ggagagattt ctagtatctc aattcaacaa ctataatcaa
     1381 aagtttctat gccgagttca taaaggtttt aaagaaatac atgatacatt agaatcaatg
     1441 ttttaacttg atcaacagaa tgggcttttc catttacaca aaattattga cgctcccgac
     1501 aaaattatga tcttgcgtaa agttataaaa tattaataaa aatattttat taatgaaaag
     1561 cttggtagca cggttattca tatgctaatt tatttcactt tatagtaagg ggagttctta
     1621 gtatattgtt caaacttaaa tttcatataa tttaattatg taaattagct attctaagaa
     1681 cttctacgga taactgcccg tctaaaattt aaataagagc ttagaatctt catataagta
     1741 aggttaattt ttttgtacaa aaaagtcgga atattctgag ttactgaaat gatataaaat
     1801 cataaactaa atcccttgat tttattgact ttcaaaagtt tatatatata agttaatgat
     1861 tatggtaaaa tatatacata atcattaact cagaatattt ttaagaaggg aaacaatagt
     1921 gagctataat gtacaaccgt taaggacaaa tgaagagata caagattttc agttttggct
     1981 aagaagaaca agtaatccgg aaagagatag ttttttattt ttgtttggaa tcaataatgg
     2041 gttacgtatg tcagatatta taggattaaa agttggagat atacgaggca aaagtaagcc
     2101 tattattgtt gaacataaaa caggtaagcg aaaaccgatt tttatagata atttgagaga
     2161 agaaatttta ttatatactg aaggtaaaga agaaaatgat tggttatttc cgagtcggca
     2221 acaaggtcga catataacaa gggatcgtgt ctatcagata tatgcagata tagcagaaaa
     2281 attaggacga gatgatatag gaacacatac attaagaaaa acttttgggt atcactacta
     2341 caagaaaact agagacattg ctaccttaat gtttattttt aatcatagct cgcaagcaat
     2401 tacaaaaagg tacattggta taactgaaga tgaaatagga gcatcacttc gtggatttaa
     2461 actaggtgta taatttaaaa atttttataa acagtaaaga caaagattaa aagctatttt
     2521 tatctagaac gattttattt cataaagttc gcggaataaa agctggggtt actggtactt
     2581 ggtataggtt cgtgttatat aaactaagta attaaataac atttttaggt tggaaaagga
     2641 tgaaattaaa aaaagagaat caatacggtc tcaaaaacgc aaacgctgcg gaataagaaa
     2701 aatactgata actcaacgtt tagcagacta tctaataggg atagtctgct tttttcgttt
     2761 ttgaccatac ttttgacctt ctgcaaactt ccttgctttt cctctgtaga actcatgaaa
     2821 tctgcaaaac gaattgccgt ttcctctgtc tgctttttcg cgatatgggt gtatatatca
     2881 tccatagtgg ttttaatatc tgtatgtcca agtcgaacat acacttcttt gacagacgca
     2941 ccagattcaa agagcagact acaatgggta tgacgaaaac catgaagtgt gatatgtttt
     3001 aagttattct ctttaatgat gattttcaaa ttgtgattta catagtctaa ataaaggggc
     3061 ttattttctt ctgatgaaaa caaaagttgt tcaccatctt ttataggttt gattctcatt
     3121 tttagatatt atgcccgcac gtattcatca catttctatt gtgaatcgct ttattcgacc
     3181 gacatttgac ttttatcata atatactcgg tttaaaatta ctaatgaaaa caattaatca
     3241 agacgatcat accatgtatc acctgttttt ttcagataat caccaccgtg tgggaactga
     3301 actgactttt tttgaagtac aagaagggaa caaccagttt tttggaacca atacgattga
     3361 acgaacgata ctaaaagttc cttccgaagc atcattgcat ttttgggaaa tatattttga
     3421 aacacaaggc gtttgccatt atggaatcga atcattttct ggacgaccta tcttacgttt
     3481 tgaagggcca gatgcaacac gattagcttt agttccctta cgcgaatttg aagatattga
     3541 tgattatttc ccgtatgtca cagaccagat ccctacagag catgccattt taggaattga
     3601 tgccattcaa ctacgcgtac aatattccga tgcgactgaa cgagagttat tgtcggtagg
     3661 ctggtagcac aaagaatacg tcagtttctt ttcgggtcat caacgagtga caatcttaga
     3721 aaatcaagac actcagttct atcaagaagt tcagattatt caagatcgtg agaatccagt
     3781 tgccattgaa gggattggta gcgtccatca tgttgcgttt ggcgtagaaa ataaatctga
     3841 tttacaacgc atcgacaaac aattacaaga gcgcaatttt ataaattcag gaataaaaga
     3901 tcgtgaattt tttgtatcac tttattatcg tgacccaaat caattattga ttgaaattgc
     3961 tacaggggaa ggaaacctag atgcaaaagc gtatgaaaat caaagtccac gctttgaaga
     4021 aattccttta tttttaccgc agtacttaaa tttcattcgt gaacaagtgg agcaataatt
     4081 agctaatcaa atccatgacg aagagtaaga ggttgactca taagtcaaaa aataaagaaa
     4141 aacgcatcaa atccattcta aagaatgttg atttgatgcg gttcctattt ttataaacta
     4201 tcattttcga ctaataaaac tacttatgag tcagcctctc tttttttctt gatttttata
     4261 cctctttcta ggtaaactaa acatctgcca aaaataccgt gtctcattga aacattctca
     4321 actatttcaa aataaagggg agtaccaaat gaacgagtat attgaaatta tccacgcaag
     4381 agaaacaact taaaaatgtc agtctcaaaa ttcccaaaaa taaaattagt atttttacca
     4441 gcgtatctgg ttcaggaaaa tcatcgattg tttttgatac tattacccaa gaagctggtc
     4501 gtcaactgaa tgacacctat gatagtttta cccgtttatt tttacctaaa tacagtcgtc
     4561 cagaggttga tgagattgat aatctttcta cggcgattgt ggtcaatcaa aagaagattg
     4621 gtggcagtgc gcgctcaacg ttagggacga ttactaacat caatgcgtta tttcgtgtgt
     4681 tgttttcatg ttttgcaaca cctagtttag gatatgcaaa tgcttattca tttaatgatc
     4741 ctagtggaat gtgttctgtc tgtcagggaa tcggtaagac gattgcattt ttaataggat
     4801 tgctttattt ttcggctatt gataatgctg attttgtatt ttctgatcca tttaccgcag
     4861 aagttttgtc tggaattgag gaacaggcaa agaatcatgg ttattttgta ttggtgcata
     4921 atgttaattc agcagaagat gttaaaacta ttcagagaaa ttggcgtttt gaggggttca
     4981 ttgttgttgg tgtacgtgta aaagaatttt tggaattaaa taacgttttt gatggtcctg
     5041 ttgtttatat tgatacgcat ctttcaaaag agacattaag agaacttgaa caacaaatga
     5101 atcgtttatt tgtaaataca aatgattacc aagctagtac attggcagtg gaacatttga
     5161 ttcattatgg tcatgagaaa atagcgtttc tttcttttga ctacattgta ggtgaaccaa
     5221 gtgttattca agaacgacat caagcttata tcgatacatt aaagaaatat catttaacct
     5281 ttaaatcgca ttggatatat aacaactctg aatttgagcg aatttatcaa gaattagctg
     5341 aatttactgc aattgttgtt actggagatt atttagcggc taaattagta aaatttttaa
     5401 aaaataagaa taaacgagtg atggaacaat tatcgattat tggatttgat gatattactt
     5461 ttgcagaatt aatggatcct gcgttgacaa caatacgact aaatccaggt aacaaggggg
     5521 cgattgcttt tcaccaactg attggactgg ccaaacaaga agaaataaaa aatcaagtac
     5581 tactattaga gggagaattg atttctcgag actctgttca caaaatcaaa taaaaaagct
     5641 ctgtgaaata agtatagtta acaataaaat atccgaacga tagagagaat gaactgtgat
     5701 ctagcagttc ctcgtcgcaa attcactaga attagcatta tttactctaa attgttcgga
     5761 tattttttct tgtttttaat tatgattaca gtgcctattt ttaacgaaat ttgcttattt
     5821 tcaaaatgta tgattatatg ttagtaaaca ctttcaaata tgaaaagagg agctattatg
     5881 gtaggaatta gggatgttgc aaaacgggcg ggtgtgtcca ttgcaacagt atcgcgcgtg
     5941 ctaaatgagg atccgacact ttcagtaacc gatgaaacca aacgaaagat tgcagaatcg
     6001 gttaattttt atcattatgt caaaaaaagt cccgttgcaa aaaatttaac aaatattgca
     6061 ttaataacga cagtttctga agtagatgag ttggaagatc cctattttcg aacgattcgc
     6121 agagggattc aagtcgaagc agaacaaagc aaagtcaatt tgaagaaaat tattcgtttg
     6181 tcagaaacac cgttggagca agacgatttg ctaaaatgtc aaggtgtgtt gattattggg
     6241 caggtgctat cttctgtgat tgaagaagta tcagcaatta attcgaatgt cgtagtgatt
     6301 gatgacccta gtattgaagc tgaagtagat gcagtttata ctgatttaac aaaagcaacg
     6361 aatcagcatt tagatcgatt gtataaaaaa ggacaccgaa acattgcgtt tatcggagga
     6421 ggacgtgttc gtttagatag ccaaggaaat aaacacgtgt cagatgatga ttatcgaaaa
     6481 atagcctatg agacgtggat gaaacaaaaa ggattagaaa aatatagtca aatttattta
     6541 gaaggctgga ccacacttga cggaatgcag gcagcagatt tacttttgaa aaaacatgct
     6601 aaagataagt tgccgactgc tatcatggta ggaaatgatc ctattgctgt gggggtttat
     6661 cgttcacttc aaaaaaatgg tctacatatt ccagaagata tttcgattgt gagttttgat
     6721 aatattgaag ttgctgaatt tttaacacct gcattaaata cggtgaatgt gaatacagaa
     6781 gaaattggaa aactagcagt tcgcatggtt aatgaacgaa taaaagaagt tagaaatgtt
     6841 tcgatcaaag tgattgtttc taataatatt attgttagag aaagtgaaaa aaatatcgat
     6901 taaaaaagta aacatccaaa aaagggtgtt tacttttttg tttactaata tttttagtaa
     6961 aaaatctcga caaaacatta agtaaacagt tatggtgttg ttaacaaaaa gaaaacgcat
     7021 tcaaaacagg aggaattaag atgaaacatt tcaaaaaaat agctttaaca gggatagctg
     7081 ttttaactgg gacattactc gcagcatgtg gtgggggaga tagtaattct aaagacgggc
     7141 aagtaacttt aagctatgcg agttgagata ctgaccaagc tccaggacta agaaaaatgt
     7201 tagatgaatt tgaaaaacaa aatcctgata tcaaagtaga aatggagaca acgccttggg
     7261 atcaatattg ggttaaatta gaagctgcaa caacgggagg taatatgcca gatgtagtaa
     7321 ccatgcactc tagcgaatcc tataaatata tgtcacagaa tgctttgatg ggacttgatg
     7381 atgttatcaa agaaaatgat attgacatgg gaaactttac tgaaggaatt gctgatttct
     7441 atacgcttga agacgaacta tacgcaatcc ctaaagatgc ttctgtagtg gggctatggt
     7501 acaacaaaga attatttgat aatgcaggtg tcgattatcc agatgaaaca tggacatggg
     7561 aaacactcag acaagctgca attgatttaa cagatgaatc aaaaggcatc tatggttttg
     7621 catcacatat tggaacagag actggctact ggccatttat ttatcaaaat gggggagaag
     7681 tatttgccga tgacaataca aaatcaggtt tgaatacccc agaagcacaa gaagctttag
     7741 ctttttatcg agatattgca cttgttgatc atgcttcacc aacaattaca gaattacaag
     7801 atcctgataa gttaagtcgt tttcaatcag gtagattagc aatgatgatt gaaggaaact
     7861 ggtttgcacc gggatttttg aaaaatgact atctagttga aaatgttgct tctgccgtgt
     7921 tacctaaggg aaaagttaat gcaacaatta caaatggact tggttgggct gccagtgcga
     7981 gtacaaaata cccagaagaa gtgaaaaaac taatggcatt tttagctagt gaggacgcca
     8041 ataaaatcca agcggaaacg ggggcatcaa tcccagcact aaaaggcttt gaagacgagt
     8101 gggctgcttc ttcagataca attgatttga gtgcttttgg aaaaatgttg gagtatggag
     8161 tccctcgtcc atacaataaa gatggattac gagctgaaca agcagaagtt caaattatta
     8221 accgtattct gtctggtgaa gtaactgttg aagatggaac cgctcaaatt gaaaaagaag
     8281 tcaatgcgat attgagcgga aattaaatta gttaattata caatatacag gcgaaaggat
     8341 tctatttcgt ctgtatatta atggatgaat accaaaaagg gggatattat gaaaaatcga
     8401 atttttggaa aatatcgtaa agatcaagtg atatggggct atatttttat ttttccaacg
     8461 gcattaggat taattttatt aaatatatgg ccagcaattc aaacagcaat tttaagtttt
     8521 caaaaaacgg tagggttcgg tgatactgaa tgggtcggat taagaaatta ccaaaaaatg
     8581 tttgcagacg gtgaagtttt tcagtcttta ttaaacacat taatttatgc agtggtttcg
     8641 atacctagta ttgttgtatt atccttgttg gtggcagttt taatgaatag aaaagttaaa
     8701 ggattgtcga tttatcggac aatttatttt ctaccagtcg ttgctgcacc atccgcagtc
     8761 gcaatgattt ggcgctggat gttcaataat gattatggac tgattaataa catgttggct
     8821 aaaataggtc tcgatggacc agcatggtta acggatccat cgattgcgat ttattctatt
     8881 atcattgtag gagtttggag tgctattggt tataacatgg tgttattact agccggctta
     8941 taagaaattc ctaaagatta ttatgaagca gcggaaattg atggtgctag tccaatccag
     9001 cagtttttca acattacgtt accattagtt acaccaacat tattttttgt agttgtaaca
     9061 acagttatca atgctttcca agtatttgat gttattttta tgatgattac tcctaatagt
     9121 accgccatgt ttaaatcaca atcattagcc tatttattct ataaacattc atttatttta
     9181 aatgacaagg gatatggttc ggcaatcgtt atgttccttt tagtgattat attaattatt
     9241 actgcaattc aaatgaagtt gcagaaaaag tgggtaaact attaaggagg ctatcaaatt
     9301 atgaaaaata aatttttttc aaatgcgcca atccatatca tgcttatttt aggtggtatt
     9361 gcaatggcat taccttttat ttggatgatt ttaacttcag ggaaaacgtt ggttgaatct
     9421 acccaaattc cacctacaat tttccctgag aaatttcagc taagtaacta tcaacaagta
     9481 cttgatttat taccattcat ggctttttat atcaatacat ttttaatggt tgttggacga
     9541 gtgattggct cggttttatt ttcagcaatg gctgcatatg cttgtgcgcg tctaagtttt
     9601 ccagggaaaa atatcctttt cagcttagta cttattcaaa tgatgattcc cggttccatt
     9661 tttattactc cacagtattt attagcacaa aaattgggta ttttaaatac aattccagca
     9721 ttaatattac caggggtagt tagtgcgttt ggtacgtttt tattaagaca atttttctta
     9781 ggtttacctg atgaattgga ggaagcggcc tatttagaag gtgccaatat ttggacgatc
     9841 tttttcaaaa ttatgttgcc gcttgctaaa tcaggattgg ttgcacttgg aatattcaca
     9901 gcgttgtttg catttaaaga tttaatgtgg ccattgattg tcaatacttc aattgataag
     9961 atgcctttag ctccgggatt agcaaactta caaggacaat atgccacgaa cttcccacaa
    10021 ttaatggcag gttcgttatt agcaatttgg ccaatagttg tgatattcat cgttttccaa
    10081 agaaaattca ttgaaggaat tgctacaaca ggtagtaaat tataaaacta ttaattagtg
    10141 attggagagt aagtacatga caaaaattac atttattggt gcaggaagta ctatttttgc
    10201 aaaaaacgta ttaggcgatg cgatgttaac tccaagtcta caagatgcac atattgcatt
    10261 gtacgatatt gatgaaaaac gactaaaaga atcaaattta atgcttaaaa atattaataa
    10321 aaattcgaat gaaaatcgtg ctgatattgt ttcttattat gatcgcaaag aagcgttaag
    10381 agaggctgat tttgttatca atgctattca agtgggtggt tataaacctt caacagtgat
    10441 tgattttgat attcctaaaa aatatgggtt gcgacaaact attggtgaca ccatggggat
    10501 tggtgggatt tttagaaccc tacggacact accagtaatg ttagactttg ctaaagaaat
    10561 ggaagaagtt tgtccaaatg cttggttatt gaactataca aatccgatgg cgatgttaac
    10621 catgggtgtt ttaaaagcga cgagtattaa gactgttggt ttatgtcata gcgttcaagt
    10681 atgcgtacca gaattgtttg agcatttagg aatagccgat caatatgact taaatgactt
    10741 tcaatggaaa attgcaggca ttaatcatat ggcattcttg ttggaaatta caaaaaatgg
    10801 ggaagatttc tatccaacaa ttcgtcagtt agctgcagaa aaaccaaatc cacatccaga
    10861 ttctgtacgt tttgaattgt tgaaacgttt tggttactat attacagaat caagtgaaca
    10921 caatgcagaa taccatccat actttattaa atcaaaatac ccagaattga ttgacgaatt
    10981 agggattccg ttggatgaat acttacgtcg ttgtgaacaa caaattaatg attgggaaag
    11041 catgcgagag gacattgtaa ataatgggga gttaacacat acgagaagcc gtgaatatgc
    11101 ttcatatatc atggattcta ttacgacagg aactccgtca gtgattgcag gaaatgtctt
    11161 aaataaaggc ttaatcacaa acttaccgac agatgtttgt gtggaagtac cttgtttagt
    11221 cgataaaaat ggcgtgcaac caacctatgt cggtgaattg ccaacacaat tagctgcttt
    11281 aaatcggacg aatatcaatg ttcaagaact gacagtagaa gccgctttaa cactagataa
    11341 atcaaaaatt tatcaagcag cgtatttaga tccacatcta tcatctgaat tgtctttaac
    11401 agatatcaaa aatttagtgg atgatttaat cgaagcacat ggggactatt tacctgaata
    11461 taattaaaaa gaagctgaaa gagtaaggaa ttttcaattc cttactcttt tcttagttaa
    11521 atttagtaaa aatattgaca aaacacttag taaacagtta cattagtgtt aacaaaaaga
    11581 aaacgcattc aaattgtata aggaggagca taaaatgaag tggtctaaaa aaattatttt
    11641 agcttgtata gcactaggag caacgatctc tttgactgct tgtggaaaaa atcaggaaga
    11701 tgcaagcggt aaggtagaaa tagagttttt taatcaaaaa aaagaaatga ctcaaacgat
    11761 tcaggagatt gctaaagatt ttgaagcaaa aaaccctgat attcatgtaa aagttgtgga
    11821 tgtaccgaat gctggtgaag taattaaaac acgtatgctt gcaggcgatg taccagatgt
    11881 cattaatctt tatcctcaaa gtatagaatt gaaagaatgg gcgaaagctg gttatttaga
    11941 ggacttaacc gaagaaccgt atttagagaa tatcaaaaat ggatatgcac aacgttttgc
    12001 tattgaggat cgtgtatata gcataccatt aaccgctaat gtctatggtt tttactataa
    12061 caaaactgct tttgaggaaa tggggattca agcaccagaa acttgggcag aatttgaaaa
    12121 aatagtagct gagattaaag atcaaaacaa agtaccgttt gcgattgcag gagcagaagg
    12181 ctggacttta aatggttatc accaactagc tatagcgact gctgctggtg gtgaagagga
    12241 agcgaacaat gtttggcgtt tctcagaagt taatggaatt aatgctgaaa gcaaagaaat
    12301 gcaaaaagat tttaatcgat tagatttgtt aagagaacca aaagctttgc aaaacaactg
    12361 gcaaggtgcc ggttataacg atacagtagt tacttttaca aaaggtgatg cgttgattat
    12421 gccgaatggt tcatgggcaa tgccgatgat tcattcacaa aatccagatt ttgaagtagg
    12481 aacttttcct tttccagcag atgaagcagg tcaaagtcta acgattggcg caggagacct
    12541 agccttatca gtttctgcaa cttctcaaca taaagaagaa gccaaacgtt ttgtagaata
    12601 tatgacaaca cctgaagcga tgcagaaata ttatgatgta gatggtgcac cgtgtgctgt
    12661 tgagggcgtt atcgagaata ctcaggattc accattaagt ggtttaactg aacttgcttt
    12721 tactgatcgt catttagttt ggttagccaa agattggaat agtgaaaatg atttttatac
    12781 cttaacaaca aattatttac acaatggcaa tcaaaaagcc atgattaacg cattaaatgc
    12841 tttctttaat ccaatgaaag ctgacggaag gtaggaaaat aaaatgaaaa taaaagaaat
    12901 tttaaatcgt tactgggcaa tcatttttgt agcaattcca attattttgc agatgatttt
    12961 tttctacttt ccaatggttc aaggtgcttt ttacagttta actaattgga ctggtctgac
    13021 ttataatttt gattttgtgg gtttgaacaa ttataagatt cttttttctg atccgaagtt
    13081 tatcaaatcg attggcttca ctttaattgt gacgctttgc atgattgctg gacaaattgg
    13141 ttttggtatt ttgattgcgc gggcgttgaa cgcaaatatt aaagggaaaa cattctttag
    13201 agcatggttc ttttttccag cggtcttatc gggcgtggtt gtttctttag tatttaaaca
    13261 aatttttaac tatggtttac caaaaattgg tagtatgtta ggcattgaat ttttacaaac
    13321 cagtctttta ggaacaacat ggggagcgat ttttgcagta atttttgttt tactttggca
    13381 aggaattgcc atgccagtca tcattttctt agcgggtttt caaagtattc cacaagaaat
    13441 tattgaagct gctagaatgg atggggcgaa tgataagcaa attttttgga atattgaaat
    13501 cacctactta ttaccaagta tttcaatggt atttattatg gcattaaaag gtggcttaac
    13561 agcatttgat caaatttttg ctttaactgg tggtggacca agcgatgcca caacatcttt
    13621 ggggttactt gtttataatt atgcttttaa aaacaatcag tttggttatg cgaatgctat
    13681 tgctttagtc ttatttatct taattgggat tgtttcactg gcacaattaa aattatcgaa
    13741 aaaatttgaa atctaggagg tttcccaatg aaaacatcaa aagaaaaaaa tatttctaaa
    13801 tacttgcttt tattattagg gggcttcatg attttagttc ccttagtttc aacgctattc
    13861 ggttcattta aaacaacacc cgatattatg aataatttct ttcgttttcc taatccagcg
    13921 actttggaaa atttccgaag attgttagcg gatggaattg gtcattactt ttggaattcg
    13981 gcaatcatca caatcattgc agtagttgct gtgacagcaa ttattcctat ggctgcttat
    14041 tcactagcaa gaaaaatgac tcgtgggaaa gcatacggat tgatgtattt atttttaatt
    14101 ttaggaattt ttgttccttt ccaagtaatt atgattccga ttaccgttat gatgagtaaa
    14161 attggtttag caaatatgtg gggattaatc ttactctatc tcacttatgc cgtaccacag
    14221 acactatttt tatatgttgg ttttattaaa ctaaatgtgc ctatcagtct ggatgaggct
    14281 gctgaaattg atggggctag tcactttaca acttatttca aaattgtttt cccaatgtta
    14341 aaaccaatgc atgcgacgac tattattctt aatgctctat ggttttggaa tgatttcatg
    14401 ctaccattat taattttaaa tcgtgattct aatatgtgga cactaccatt gtttcaatat
    14461 aattatacgg gacaatattt taacgactat ggtccaagtt ttgcttccta tacagtagga
    14521 attgtcacga ttacactagt ttatcttgct ttccaaagaa gtattatagc tggaatgagc
    14581 aatggagcag tgaaataacc aataaattat tctcattata aaggagttca taaacttatg
    14641 attatatttg acaatcacac acaaacattt catttacaaa ataaaaaaat tagctatcta
    14701 ttaggaatcg aagaaaataa ttatttaacg catctttatt ttggaaaaaa gattacgcac
    14761 tattctggtg ggtatcgcta cccccgaaca gatcgttcct tctcacccaa caatgcaaat
    14821 gcgcaagatc gtttattatc tttagacaca ttaccattag aatttccagg atatggacat
    14881 ggtgatttta gagaaccggc gcataatatt aaattaggaa acggtagtcg tgtaaatgat
    14941 tttcgttatg atagctacga aattcaaaaa ggaaagccca gcttagcggg attgccagcc
    15001 ttatatacgg aagatgatga tgaagctgaa acgctgatta ttcaattgaa agacgcgatt
    15061 agtggattga ctttacagtt gttctacaca atttatcaaa atcacagtgt aattattcgt
    15121 tctacgcaat tagtaaataa tagtgatgaa acagtggaga ttaaccgctt agctagtcaa
    15181 tcaattgatt ttccaaatcg tccactcgag ttaattcatt taaatggtac ctgggcaaga
    15241 gaacgtcaaa tgactagaga aaaaattcat acagggataa aagtattaga tagtaaacgc
    15301 ggatcaagca gccatcaaca aaatccgttt gttgctttag tagatgccaa aacagatgaa
    15361 tttcaaggag aggcatatgg atttaattta gtttatagcg gtaatcacga aacggtgatt
    15421 caaaaagatc catttgacca aacacgggtc attatgggaa ttaattcatt taattttggt
    15481 tggcaactaa aaactggcga ctcatttcaa acgccagaag tcgtgatggt ttatagtaat
    15541 gaaggtctga atacgttatc acagacgtat catgaattgt ataatcaccg tttaattcgt
    15601 ggaaactatc gtttaaaaga acgtcccacg ttaatcaaca actgggaagc aacgtatttt
    15661 gattttaacg aagaaaaaat catgaatatt gtcgatgatg cgaagaactt gggcattgaa
    15721 atgtttgttt tagatgatgg ttggtttggc ggtcgtgaaa atgacttcac ttcattaggt
    15781 gattgggttg aaacagaagg caaacttgct tgtggtttgg aaaatttagc caagcaagtg
    15841 catgataacg ggatgaaatt tgggatttgg tttgaaccgg aaatgatttc tgaagatagt
    15901 gaactatttc gagcacatcc agattgggca ttgggtattc caggtcgtga ccgctcaatt
    15961 agtcgaaatc aatatgttct tgatttttca agacaagatg ttcgtgataa tatctatcaa
    16021 caaatgacgg cgatttttga tcgtgtaccg attgattatg tgaagtggga tatgaatcga
    16081 aatatgacag aagtctattc tgtcttgttg gactcaacga tgcaaggtga agtggctcat
    16141 cgttatatgt tagggttata tgaattttta gaaaagttaa caacgaatta tccaactatt
    16201 ttatttgaaa gttgttcggg tggaggcggt cgttttgatg caggtttctt gtattacatg
    16261 ccacaaactt ggacgagcga caataccgat gccgtggctc gtctgaaaat tcaatatgga
    16321 accagcttag tgtatccaat ttcaagtatg ggtgcgcatg tttcagcagt cccaaatcat
    16381 caaacaggaa gagaaacgag tttaactatt cgtggcaatg ctgcgatggc tggtgttttt
    16441 ggttatgagc tagatctaac gcaattaact tctgaagaaa aagcagaaat taaagaacaa
    16501 gttgcctttt ataaaaagca tcgccaactt ttgcaatatg gaacttttta tcgcttggaa
    16561 agtccgtttg aaggcaatga tactgcatgg atgtttgtct caaaagacca aacagaagcc
    16621 atggtctttt atttccgagt attagcagaa gctgcgcatc cattagtcac attgaaatta
    16681 gcaggattag cagaagaagc aacttatcaa atggaagatg taacatttgc tggcgatgaa
    16741 ttgatgaatc tcggttttta tattgactca gaactacatg gtgattatgc gacacaacgc
    16801 ttttatttga aacagatata gtagcttgaa tttacaatat aagtgcaaca ccaaaagaga
    16861 ctcattccaa acgaagaaaa tatgttttat ttacacgcat ttactaaaaa gcagcctgat
    16921 ttgaattggg aaaatgaaga agtacgtgaa gaaatctatg caatgattaa ctattggtta
    16981 gataaaggac taggcggatt tagaatcgat gcgatattaa acatcaaaaa aaaactagag
    17041 tatggcatct ttgaatctga tggagaagat gggttagcct tcattgggcc ctggattctt
    17101 aatcagtcgg gcattgaagt gtggttaaaa gaaatgagag agcggacatt taaaccacat
    17161 aatagtatga cggtagcaga agccgatgtt cctaatgaac gtttagatga atatattggt
    17221 gaagatggct attattcgat ggtttttgat tttagttata cggatattga tgtacctgaa
    17281 actggtgaat ggtttaaaga tagccaatgg acatggacgg atatgcgtac caatattttt
    17341 acgaatcaat tagttacgca agataaaggt tggggcgcct tatatttaga aaaccacgat
    17401 caaccacgtt caattaataa atatattcca gaagaatgga tcaatgatta tagtaaaaaa
    17461 atgttggcga cgctttttat gttactaaga ggtacccctt ttatttatca aggacaagaa
    17521 ctaggaatga ccaacataga aatggcatca ttagaagatt ttgatgatgt agctacgcat
    17581 tctcagtata aacgggcatt agaatatgga ttggcaccag agcaagcatt gaaagctgtc
    17641 aataaacgaa gtcgggataa ttctcgcaca cctatgcaat ggaatacgca aaaaaatgcc
    17701 agattctcaa cttctgataa tgtatggtta aaagtaaatc ctaattatcc agaactcaat
    17761 gcagaagctc agttaaccaa tcaacagtcg gtattcaatt attatcatca attaattaaa
    17821 ttaagaaaaa atagtgtata caaagacgtg ctaatctacg gacaatttct accagtgaaa
    17881 gataaaaatg aacatatttt gctttatgaa cgccaattag aagataaaat cgtattagtt
    17941 atcttaaacg ttacagcaac agaacaagaa tattatgtag atgaacagta ccaacaagta
    18001 ttaatcaata attatgaaga tgttttatta gatcaaagtc gaaaattgcg tttacgaccg
    18061 tttgaaagta ttgtattagc taattatgga ggacaattat gaaaattaaa aacgaagcaa
    18121 tgctcatcac ctatgcagat agtttaggaa aaaacatggg cgaattaaaa caagtcttag
    18181 acaaacattt acaaggtgtt attggtggtg tacatctgtt gccttttttt ccatcgacag
    18241 gtgatcgagg ctttgcgccg agtgattata cgacagttga tccagctctt ggaacatggg
    18301 aagatgtgga agcattaggt gaagattatt atttgatgtt tgattttatg attaatcaca
    18361 tttctcgtga atcaaaattt ttccaagatt tcaaaaaaaa ccatgagcag tcaccataca
    18421 aagaaatgtt tatccgtatt catgaatttt tcccagaaaa tcgaccaaca caagaagata
    18481 ttgatttaat ctacaagcgt aaagacaaag cgccgtttca aacggtagaa tttgcggatg
    18541 gtacgacaga agaggtttgg aatacctttg gggaagaaca aattgattta gatgtgacca
    18601 aagaagttgt gaaagaattt attcgagaaa ccatcaaaga tatggcgaac catggctgtt
    18661 ctttaattcg attagatgcg tttgcttatg cgattaaaaa attagatacc aatgatttct
    18721 tcgtggaacc agatatttgg gaacttttag acgaagtgcg tcaagaagca gcgaaatatg
    18781 acgtcgaatt attaccagaa atccatgagc attattccat tcaaatgaaa attgccaatc
    18841 atgattatta tatctatgac ttcgccttgc caatggtcac tctgtattca ctttatagtg
    18901 gaaaatcaga acgtttagcc aattggttga aaatgagtcc gatgaagcag tttacaacat
    18961 tggatacgca tgatggaatt ggtgttgtgg acgctcgtga tttattaaca gatgaagaat
    19021 tggattacac ctctgaggaa ttgtataaag tcggggcgaa tgtgaagaag gtctattcaa
    19081 gtgccaatta caataattta gatatttatc aaattaacag cacctattat agtgcattag
    19141 gcgataatga ccgtagctat ctgttagcac gtgcgattca agtatttgcg ccagggattc
    19201 cacaaattta ttacgttggg ttattagcag gaaaaaatga tattgaactg ttggaagcaa
    19261 cgaaagaagg gcgtaatatt aatcgtcatt actatgattt agccgaaatt gaagaagaag
    19321 tgcaacggcc agtgattcaa caattatttg cacttttaaa atttagaaat gaatctgcgg
    19381 cgtttgattt ggatggaacg attgaagtag caacgccatc agaatcagaa atagtgatta
    19441 cacgtaaaaa taaaaacggt agtgatagtg caacattaac ggctaacttg gatacgaaag
    19501 aatttatcat tgagtctaaa gatataaaaa ttttcactag tgttgcatta aaattttaac
    19561 ctattccata gaacaaaaaa tcctttatac tagcacttgg atgacttatc caagaccaat
    19621 aaaaaggact catacatgga taagtataaa acaaatacag catttaataa atggttttct
    19681 gccataaaat taggaaaact ttctgtcaac tcccaaaaat gtatttttga ttacaattcg
    19741 tatcgtaaaa aactgtcttt tgaagctgtg ctcaagctct ttctctacgc agttaatgaa
    19801 gaaaaagaaa gtttgcgtga tttgagtaca gctcttatcg accgatcgct ccaactagaa
    19861 accgatgtgt catcgattag tcatacccaa ttgtctcgag catttaatgc acttgaacct
    19921 aaagtgttag aagaaatttt tcaacaactg ttagaaaaag ttcaacatca aatcaaacca
    19981 accaagcgaa atcatctgta tctgattgat tccagtacgt tttcgcttag tttaaaacgt
    20041 cataagtggg cgactttccg tcaaacaaaa tcaggtgtca agttacactt aaactattgt
    20101 tatatggacg atactacgat gtatccaact gattttacct taacaaatgc ccatgaacat
    20161 gatctcaatc aactaccagt attggtgaat caaccagagg caacttacgt gtttgatcgt
    20221 gggtattagg actttgaaaa gatggatcag atgcattggg atggctattt cttcgtcact
    20281 cggattaaaa aaaacaccaa agttcacgtg atagatactc tggaaacatc gccagaaaca
    20341 gaaattctac gagacgagct ggttcgttta ggatctaaaa cctatctaac cgccaatttc
    20401 cgactagtca ctgttcaaga taagaacgga cgtgtgtttc aatttatcac caatcgaatg
    20461 gacgtctctt caaaagaaat ctctgatatg tatcacgctc gttggcaaat cgaattgttt
    20521 ttcaagcaca tcaaacaaca catgaccatt aaaaccttct tttctcaaag tgaaaaaggc
    20581 gtgcagaatc aattgatttt aacgatgatt tccgctctcc tcacgtttct catcaaattg
    20641 gagacgaaaa cggaaaaatc agtgttccaa atcaaacgat tctttcgtta tttactgttt
    20701 cagccctttg aatgttgtct agaaaaatta attcccacat gagaaaaaag aaatttggct
    20761 cgttactttt ggttttcagt tgaataacag ataaaaaatt ttctggaaaa agtcatcctc
    20821 tgcgtcagca cagttttttt tgacttattt tcagaggaaa tagttttcag aatattctaa
    20881 aatgttttat gcaacactag tgatattttt tagaattaga tttctaatgt gcattttttg
    20941 agtattaagg agcaagtata caaagattta taaagctgat taaatttgaa taaaaatatg
    21001 caggaacgct actattttta gtagtgttct tttttatatt tgaataaaaa atgtggtggt
    21061 taaatggtgg ttataacaaa aaatgaatta atgaaattag gttatgggaa gtatcagtct
    21121 gagagaatca tacgacaggc aaaagcaatt atggtttcaa aaagctatac ctattacgaa
    21181 aatagaagat taggactagt acctgttgaa tctgtagaag aagttttagg tatgaagata
    21241 gaggtagagg aggattttca gaatcatggt taattttaaa aaagataaaa atgggaaata
    21301 tcattttact gctagtttgg gattcgacaa acgaacaggg aaaagagtac aaaaaaacgt
    21361 agaggggtta aaacagttaa agaagaaaaa aagcgtatac cgaacttgtt tctaattatg
    21421 gaaaagaagc agaaacttct caaagtacta tgttgtttga ggagtttttt tataaattat
    21481 tcctacctta ttatcaaggg aaagtagaag aaagaacata taaaaatcgg ttatctacaa
    21541 tcaaaaaaac ttttcttatt tctttaaaat ggagttaaga gaaatacgtc caattgacat
    21601 tcaaaagtgg caaaataatt tattgagcaa atataaaaat tcttatgtaa gaaacatgta
    21661 tgggattttt cagatgtcat tagatcgagc agttgttttg ggactacttg aaaaaaatcc
    21721 tgcaaaagtt attggaaatg tgaagaaaag gaaaactaca gttgattttt ggacaaaaga
    21781 agaatttaca aaagttattt caacttttta tattgatgat ttgtaccaac attttggttt
    21841 tatttgtatg tggttacttt ttatgaccgt tatgcgtttg ggagaagcca ctgcattaac
    21901 ttggaaagat attgattttg aaaataaaaa cttgcgtgtg aataaaacac tctattataa
    21961 gagagccaaa acctatgagt ttgtagaacc cgaaacggct tctagtattc gtacaatcga
    22021 actagacgac aatacaatta cctttttaaa agcttggaag gagcgtcaag tttcaatagg
    22081 aggcatgtcg tttgtacttt cttataatgg aacacctact cagaaatata caatccgtca
    22141 tattatgaga agacatgcaa cgatcgttgg tgttcatata atccgcatac acggattaag
    22201 gcatagtcat gcttctttgc ttatatcaca ataaaaagat gcacttcgaa ttaaagaaag
    22261 gttaaaacat gctgatgtac aaacgacttt aggaacttat ggtcatttgt atctaaattc
    22321 attgagagag ataacaaatg atcccacaga ttatatccaa actaattttt ctaaaatcaa
    22381 accgacacct atttacgata ataaaaaata aatgataaac aaaagtagga tcacaccaaa
    22441 agaaacacac tagaaaaact ataatacagg cttttctagc gtgttgtttc ttatttccgc
    22501 ctatttatac attatactca taaagcattt aatgcatcga tcgtagccgc attgtctata
    22561 tgggtatata aagttgttgt attggtactt gaatgtccca attgttgggc agttaatacc
    22621 aatgaatttg tctgttggta gagtctagta gctaatgtat gacgcagttt gtgagggctg
    22681 acttgaattc taaagccttt tgaatatttt gctaccatcc gttcgattgc aataccggat
    22741 atacgcttgg cttctccttg gtaaattgct agaaataaag ctttttcgtt ttctgttact
    22801 ttatatcgtt ctttccgaat agctagataa ttagctaaat attccattgc gaatgctgct
    22861 atattgacag catctctttt atttcctttt ctagttacta ccacattatt cttatctaaa
    22921 gataggtcat ctaaattaat atttataacc tcggagagtc tcaatccaga tcctaaaatc
    22981 agtgcattga tcgccaggtc tctttctaca tctcgttgat aatagatcaa agctcgttta
    23041 ctcaaagtat ttttatattc attggcaata taatctagat aattttgtgt atccttatct
    23101 agaaataatt ttttctcaat ggcattggca cgtgcagcta acgtagtttt atctgtgatg
    23161 gttgctactt gatccatagg attattgtct aagtatggtt ttcctagagg attattggaa
    23221 cttttcgaaa gatatttaaa tagaaccttt aatgccgtga tatttctatt gatagtagaa
    23281 gtagatagac ctaagttatt attatctttg agcttagttt ttgttgtctc tttttttaca
    23341 ttttcttttg tgcgacgttt caaatgagat ttgtacaagt ttaggtcata ggcagttaac
    23401 tgtcttatcg aggtgataga agtatcagga acgatagact cactcagaag ccattcataa
    23461 aagagcttat aattttttag atattctaaa gtggttcgag gtgattgatc tttatcctca
    23521 cgatcttgaa caaaatcttt tatataatcg ggcatatgaa gtatgattgt atctattttt
    23581 tgatatattt ctgtattttt catgtcattc atcctttcaa taagtagggg agaagagtat
    23641 ctctataatt ggactatacc aattatagaa tgttttgtca attggtatgc tctaaaattt
    23701 attaatttgt ttcaaaaaaa gcatataaac aggtatacgt ttaataattt aaaataaatg
    23761 gtatacataa atagggaagg aaatagaagg gagcaatcta aattttttga attttcttaa
    23821 ttaattatat agaaagaaca atctttctat agagttagac atgagaggga ctatgcttga
    23881 tttaaaatca acaagcgtat atactgtata tacaaagaaa aaggagggag aagactatgg
    23941 caattaaaga aagaaaattt agggaagtgg ggaactcagt agtattaact atttcaaagg
    24001 agtttcttaa agaaaatggg ttaaatcccg gagatacggt ttttttagat gaagaaaaac
    24061 ttcgagcggc aattacaaaa aaacaagcct tatctgatga aattgattta gcaatatctc
    24121 aagcattaac tgaatatgat actactttta gagagcttgt cgataaatga gtattcatta
    24181 cctagaagcc aaagatatta taaaaatgaa tgtaatccaa ataaaaaaat actctcctaa
    24241 tgaacccctt ggtgtaaagg atgcgaatgc tttagaaatg tgtgtagggc aacttcgagc
    24301 ctcagctttt ggtgaagagg tttatccttc gatttatgaa aaagcagcta tcctacttat
    24361 acaattgata aagaaacatc cttttcacaa tgcaaataaa cgtactgctt tcttagctac
    24421 ttttgtcttt ttgaaaatca atggacagct tttagctatt gatcaaaaag atgctgtaaa
    24481 tttagcggta tatattgcta cgtatgataa ggatttcgat caactaaaat atgaagtgat
    24541 caacactata aagacacata cgcagcccat ttaaggagtt actgtatgtg tctttatagg
    24601 gttattagct gctatagcga aataattgaa gtaaattaca aatagctata attcaaatcc
    24661 aactatatag aaaacgtaaa ttttctatat agttggatta agataacgac tatttatttt
    24721 atcatatttt tactataccc tatactttta cttggtatat ttatgaataa tcgcaaattt
    24781 acccctatac tactagtttg taagttagat taataaaaat actaaagtta tttgttcttt
    24841 tattaaatac acctacaact tataaattga tggtatttag ataacacgaa agaataaaaa
    24901 taacagctga tagtaaagtt tgttgacgat tgctactcaa tcgaaagtga gttagtgcgt
    24961 atgaacttgc ttctgaaaac ttatgaaatg aaagaccttt tacatcttgc agaaatcgtt
    25021 actgggatta aactaagcaa taaaaactaa tgttcccctc attctttgaa cttctactat
    25081 ttgatttatt tattctgata aatgacgatt tcaccttcag gatcttcaaa tcccgtatag
    25141 aatttattta agatctcttc agtatcagta ataggatagg cgataggcca catacccttt
    25201 gatggttaga ataaactgct caaaatctgt atcgtatgtt ggctttagca tattaacaaa
    25261 ggctatctcc aaattataaa ccataagcgt tgaatcgttc ttaacaattt caattcttcc
    25321 taacccaaag tcagaagata taattaccgg acttgcctta cccttcatgt gggttgttga
    25381 gattccatat ttaaagggaa ttgtcggtac tatcggcggt ctgaaaaaca tcccaaaaat
    25441 aaaaaaatct ttcccctgct agtctcctaa gtccctttgt agcggatatg gcaccataat
    25501 ctcattttat cgaagtgagt catggtttat ctgttggcca accaaaattg atacaatcta
    25561 acgatgcacc ctctacggca ttctagggga gtgcacttgc attcacccaa taaaaaccgg
    25621 cagttagcaa agaacttatg tagtcgtatg ttcttactgt taacatacaa gaggtctcct
    25681 ttccacaatt gcttagcagt aaacgggaat ttacaaagct aatctcttcc attttcttat
    25741 ctttgttcta aaagtcccaa atggagcaac tgtatttaca tgaataaatt tatatacttc
    25801 ccatacagcc gttttggttg cctcgtctgc ccattttctt ttgtgtgcag tgaatagatc
    25861 ttcatcactc attgaatcaa tcatcatgtt aatatcatca atattacgat tgagaatttc
    25921 ctctaattct ttcaatggta gatgtgcata ggtatttgta aaccacttat ataactctcc
    25981 taactgattc catttaaatt gatcagaagg cgttttaaca gataatccat ttctttcatc
    26041 attttcccat tttagaatta aattcgtcca accaacttga tatgctaaat tttcagcagg
    26101 tgttctatcc acttcctcaa ctcttttatc cttcaattct tcaggaatag tttcaaattc
    26161 taaaatatat ttagtataag tcctatttat ttcttttttt aattcttctt tatttttata
    26221 tgttctcatt atattacctc cataaattcc taattgtctc ctttaattca tctataattt
    26281 catccacgat attttaatcc gttctacaat gcatatctga tatgcattga ctgtctaact
    26341 catatgtgaa tgatttataa aatatcccaa cgtctcatct aaagaaatgt tgatcgtcag
    26401 caaggagcta aaaaatacga atatatttct tttgtagtaa aatcggactg gtttgcatat
    26461 cattttcttc gtaaatatca aaatcatgtt aactactatc aattactaat aaaaactacc
    26521 actttaagcg ttaagaactg ttaagtttag ttaagtgagg atagttcaca aaatccattg
    26581 ttaaacttca cgaaagtggt aaaactcaaa atgctttata taggattaca gcatcgctct
    26641 ttcttcgatt gcgcgttggg taaaaaatat tatgaagtaa aaattgacga tgacacgttc
    26701 cttacggctc atcagatgaa acagctacaa aaacgaaatg atcaactcga agaaaattta
    26761 attctaaaaa agcgattgcc atattcacgc ctcgctcgac gaactattaa aggtcaagat
    26821 ttacctgaag atcatccttt ttaggaaatt gaagcttttt atgttgcaca atgcatttat
    26881 aatactacaa tgatgttttc accagatatt cttctagggt gcggtgtaat gaaacagata
    26941 cacttgcaaa agaaaattca ccgcgaattt actaaaatta tgaataatta tgttaatctt
    27001 ccgaaatttt tttccaaaat taagggatca agctggtgtt atagattgtt taaggttggc
    27061 aaaaaaataa cttcttttta aacaattata gaaaaccgat actctgttaa gttggttgac
    27121 acggtgtcga tttttatgac tttcttattc tgaaacttca ctaacggaca gtacctaaaa
    27181 agtctatagt atggacgttt acgagtacta ttttatcaaa aatgctgctc atttcaactt
    27241 atatgtttta gtgaactacc cccacttagc ttggataggc tacaattaac tagacagaaa
    27301 aattaaggtg tgtagactag aagaaaacat accaggagga atttttatgt ctaagagaac
    27361 acgaagaact ttttcacaag aattcaagca acaaatcgtc aatctttact tagctggaaa
    27421 gccacgtgta gaaatcattc gagaatatga actaacggct tcagcatttg acaaatgggt
    27481 aaagcaatct aaaacgagt
//
LOCUS       DAZKCH010000034        25236 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000034 DAZKCH010000000
VERSION     DAZKCH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.034"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            237..1877
                     /locus_tag="ACG84X_001443"
     CDS             237..1877
                     /locus_tag="ACG84X_001443"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFP9127319.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2031..3353
                     /locus_tag="ACG84X_001444"
     CDS             2031..3353
                     /locus_tag="ACG84X_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFP9127320.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3415..3846)
                     /locus_tag="ACG84X_001445"
     CDS             complement(3415..3846)
                     /locus_tag="ACG84X_001445"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9127321.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3910..4746)
                     /locus_tag="ACG84X_001446"
     CDS             complement(3910..4746)
                     /locus_tag="ACG84X_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFP9127322.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4936..5238)
                     /locus_tag="ACG84X_001447"
     CDS             complement(4936..5238)
                     /locus_tag="ACG84X_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFP9127323.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="ACG84X_001448"
     CDS             complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="ACG84X_001448"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFP9127324.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5692..5958)
                     /locus_tag="ACG84X_001449"
     CDS             complement(5692..5958)
                     /locus_tag="ACG84X_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFP9127325.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6212..6937)
                     /locus_tag="ACG84X_001450"
     CDS             complement(6212..6937)
                     /locus_tag="ACG84X_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFP9127326.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7303..7373)
                     /locus_tag="ACG84X_001451"
     tRNA            complement(7303..7373)
                     /locus_tag="ACG84X_001451"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7339..7341),aa:Gly,seq:ccc)
     gene            7490..8242
                     /locus_tag="ACG84X_001452"
     CDS             7490..8242
                     /locus_tag="ACG84X_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFP9127327.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8258..8737
                     /locus_tag="ACG84X_001453"
     CDS             8258..8737
                     /locus_tag="ACG84X_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFP9127328.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8988..10568)
                     /locus_tag="ACG84X_001454"
     CDS             complement(8988..10568)
                     /locus_tag="ACG84X_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFP9127329.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10561..11304)
                     /locus_tag="ACG84X_001455"
     CDS             complement(10561..11304)
                     /locus_tag="ACG84X_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127330.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11480..12256)
                     /locus_tag="ACG84X_001456"
     CDS             complement(11480..12256)
                     /locus_tag="ACG84X_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFP9127331.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12504..13340)
                     /locus_tag="ACG84X_001457"
     CDS             complement(12504..13340)
                     /locus_tag="ACG84X_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFP9127332.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13351..14280)
                     /locus_tag="ACG84X_001458"
     CDS             complement(13351..14280)
                     /locus_tag="ACG84X_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFP9127333.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14472..14825
                     /locus_tag="ACG84X_001459"
     CDS             14472..14825
                     /locus_tag="ACG84X_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFP9127334.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14899..15555)
                     /locus_tag="ACG84X_001460"
     CDS             complement(14899..15555)
                     /locus_tag="ACG84X_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFP9127335.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15781..17715
                     /locus_tag="ACG84X_001461"
     CDS             15781..17715
                     /locus_tag="ACG84X_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFP9127336.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17801..19024)
                     /locus_tag="ACG84X_001462"
     CDS             complement(17801..19024)
                     /locus_tag="ACG84X_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFP9127337.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19018..20889)
                     /locus_tag="ACG84X_001463"
     CDS             complement(19018..20889)
                     /locus_tag="ACG84X_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFP9127338.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(20910..22028)
                     /locus_tag="ACG84X_001464"
     CDS             complement(20910..22028)
                     /locus_tag="ACG84X_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFP9127339.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22111..22944)
                     /locus_tag="ACG84X_001465"
     CDS             complement(22111..22944)
                     /locus_tag="ACG84X_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127340.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22937..23854)
                     /locus_tag="ACG84X_001466"
     CDS             complement(22937..23854)
                     /locus_tag="ACG84X_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127341.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24081..25205)
                     /locus_tag="ACG84X_001467"
     CDS             complement(24081..25205)
                     /locus_tag="ACG84X_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFP9127342.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
BASE COUNT         7776 a         5037 c         4299 g         8124 t
ORIGIN      
        1 ttctatttat ctatctaaca tatcctttat tcttctactt ttctttcttt agcatataag
       61 agatacgcat agtaatcaag caaggattgt tgatataaaa agaacaaata ccgctatttt
      121 gatttctttt gactctatta ctcatataaa taaaatttat tatacctgct ctttttgact
      181 atatcctcat ctgactccta tacttcgttt gtattaaaac ttaggaggaa tcattcatgc
      241 ttacagggct aaacttatta aataatcctt ttctaaataa aggaacagct tttacaaaag
      301 aagaacgggc aaaatacgga atcactggta tgcttccaag tactgtccaa acattggaac
      361 aacaatctgt ccaagcttac ggtcaatact taagcaaaca gaccgatttg gaaaaacgta
      421 tcttcttaat gaatctattc aatacgaacc ggacattgtt ttataaattg atgggcgaac
      481 atttagttga attcatgcct gtcgtttatg atcctgtcgt tgcggattca atcgaacaat
      541 acaacgaaat tttcttgaaa ccacaagatg ctgtatttct ttcaatcgac gaaccagaaa
      601 atatcaaagc aagtttgaaa aacgcagcag atggacgcga cattcgtttg atcgttgtga
      661 cagatgcaga aggaatctta ggtatgggtg actggggtgt gaacggtgtt gacatcgcta
      721 tcggtaaatt gatggtctac actgccgcgg ctggtatcaa tcctgcacaa gtcttgcctg
      781 tatcaatcga cgctggtact aataacgaag aattattgaa taatccatta tacttaggga
      841 atcgtcatgc tcgtgtagaa ggcgaaactt actacgaatt cattgatcaa ttcgttcaat
      901 cagctactga attattccca gaattgttat tacattggga agattttgga cgaggaaatg
      961 ctgcaacgat cttagaaaaa tacgaagata aaatcactac tttcaatgat gatatccaag
     1021 gcacaggaat cgttgtacta gctggtgtat taggtggatt gaatatatca ggtgagcaat
     1081 tgaaagatca aacgatcttg acatttggtg ctggtactgc tggtgtaggt atcgcaaaca
     1141 tccttttaga tgaaatgatc cgtcaaggtg tacctgaaga agaagcacgc caacatttct
     1201 atcaagtaga taaacagggt ttattgtttg aagatacaaa aggattgact cctggtcaaa
     1261 tcccattcgc tcgtaaacgc tcagaattca ctaatgctga tgaattgaca aacttagaag
     1321 cagttgtaaa agcaatccat ccaacgatca tgatcggtac ttctacccaa cctggagcat
     1381 tcactgaaga aatcgtgaaa gaaatggcgg ctcatacccc acgtccaatc atcatgcctt
     1441 tgtctaatcc aacaaaattg gcagaagcaa aagcaaaaga tttgattgaa tggacggacg
     1501 gaaaagcttt agttggaaca ggtatccctg ctgctgatgt ggaatataac ggtgtaactt
     1561 accaaatcgg tcaagcaaat aatgcgttga tgtacccagg tttagggctt ggtttgattg
     1621 cttcaacagc tacacgagta aatgctgaaa tcatttctca agctagtcga gcattaggcg
     1681 gaatcgttga tgtaacaaaa ccaggagcag ctatcttgcc tccagtagca aaaatcactg
     1741 aattctctca aacgattgct gaaactgtcg caaaatcagt tgttgcacaa aaattgaatc
     1801 gtgaagaaat cacggatatc aaagaagctg ttgaatctgc taaatgggtt cctgaatata
     1861 aatctttaga agattaagat tgttatagta aaagaacata cagaaacttt gtatgacgtc
     1921 taaaaagaaa aaagcgactg cggcaaaaca gcagccagcc aactactgct cttttgccgc
     1981 ttctctttgg cttttttcat acgatacaga ataagaaagg atctgtaaaa atggcacaaa
     2041 aaacaacaac cgcaactgca gttgaggaaa agaaaaaaga agggttttgg tcaacaaaaa
     2101 ttaccggcgt aagtttgccc ctttatttga tcatggtcct tgtcctgatc attgcaatgg
     2161 ctttaggaaa attaccgacg aatatgattg gcccaatcgc tgttttggtc attttcggta
     2221 atttatttca ttttatcgga acaaaaatcc ctatagtcaa aagttattta ggtggtggct
     2281 ccgtttttgc gatctttgcc tctgccgcga ttgctacatt tgggatctta cctgagtatg
     2341 tagtaaaatc cacagaaaac tttgtcagca atatgggctt tttagacttt tatattgctg
     2401 ccttgattac tggtagcatc cttggtatga accgtaatct attgatgaaa gcttctgttc
     2461 gttttattcc cgttgcactt atttcaatgg tcgtctcctt ttttgccgta ggactcgtag
     2521 gtatgcttat cggaaatggt tttgcaaatt ccgttttata tatctcattg cccgcaatgg
     2581 ctggtggtgt tggagccgga gctgtacctt tatcaacgat ttatgcaaat gttttaggta
     2641 cggacgcttc ttctatcatt tcccgcctga ttcctgcgac agcaatgaca aatgtcctag
     2701 ctatcattgg tgcagcgtta gttgctcgtg cgggacaatc aatgccaaaa ttcaacggta
     2761 atggtaaatt aatggaaaaa ggcgaccttg gcgatggaaa acctagaaat gtaaaacctt
     2821 ccattccaca attaggtgtc ggtttgatgg tatcattgac tttcttcatc ttaggacaaa
     2881 tctgtaacta ttttgttcct aaagtccatg cttacgcatt catgatcatt atcgttgtta
     2941 tctgtaaaat cgcaaaccta ttaccagaat attacgaaga tgcagctatc atgttcaaca
     3001 acttgattgt caaaaacttg acagcagctg ttcttgccgg tatcggtatt gcgttattga
     3061 atctaaatgt attggcttct gctttgacat ggcaatttgt tgtcttatgt ttgacaagtg
     3121 ttatcgcgat ttcagtagtt tcaggatttg tcggtcgttt gtttggttta tatccaatcg
     3181 aatcaactat tactgctggc ttatgcaaca actcgatggg tggtacagga aatgtagctg
     3241 tcttatctgc agctaatcgg atggaactta ttgcttttgc tcaaatgggc aatcggcttg
     3301 gtggtgccat cgttttgatc atctcaggtt tcttgatgca attactttct tagtcaaaaa
     3361 aaatacctga tcatcaagta tcggcttgat gaccaggtat tttttgataa aaatttacag
     3421 gattttcaaa aatctttttt gcattttatc ggaatgataa ccgatgcgtt cataaaatcg
     3481 gtgtgcttct actctgtatt ctgcagaatt aagtcttatt gctgatattc ctcgtctttt
     3541 cgcttcttct acgccagtca tcaaggcctt tccgattcct cttttttcag catgtttaga
     3601 cacagcaagt gccataatat tgaacatcgg atcgctgaaa atcgattcat aggactccgc
     3661 ttgtacatag ccagctgctt ttttagaagt aggatcttca tagaccaaga aaaaattttt
     3721 ttctggctcc ttcaacagtt tcttcatttg tctcaccgta acggttaatg gtacatcata
     3781 tcctaattgt tccgcattga tttctcgtag tgcttctgca tctcctaaac gcatttcccg
     3841 caacatccaa atcaccagcc aatttttatt tttttaaatg aattttttta tcacagtata
     3901 ctcctttttt cacttaaaaa aagacttttc agtgattttg acttgcttga atccagatcc
     3961 ttctaatgtt tgcaagatga cgaaagcatt gtaaagattg atcaaaagaa ccacgatgac
     4021 aatcgcttga aaaataaagg tcactttttt tggagacaaa accctgctaa atcttgctcc
     4081 ccacaaacct ccaataacag cagcggggat aacataaaac aacatagata aatcaaagcg
     4141 cataaagcta cttgttaaag caatcgttac caattttgcc agttgagaaa agaaaatcgt
     4201 agatagagaa tatagtgttg cttcttttat tggcaatgca aacatcagca tcaacaaaga
     4261 aacattgact ggtccaccac caatacctaa aaaactagct aaaaagccca gaaccccccc
     4321 acatataagg taccaagtcc atgacgtcaa atgaaatttt ggctgatgat gcttggtgta
     4381 gaagaacgca aaaaccaagg tcaataccgt caaaaaaatt tggatcagct gcacatgctt
     4441 ctcgttttca aataactgta aaaaaacttc gaatacaatg ttgccgacta ctcctccaac
     4501 aacagctcca ctagataccc aaccgacaat ctgccaattc agtgatttcc cgcttgatac
     4561 ttgtcgcaca gtcgaaacaa tggacatcgt gaataccgca actgttgagt aaaaagaaat
     4621 ccctgcaaca gaatgggcgc cgataagatc aagaatcggt ttgatcaaca cgcctccacc
     4681 catcccggaa atagcgccaa ctgtgttcgc cagaacgatc accacaaaat aaatcagacc
     4741 aatcatcttg tatttccttt ctcttgttta tatcttttag cgattgttac tcttttcttt
     4801 tattatacag taaaagaaac aaacgaggct tcgaaagctt ttctactttt taaggaaatt
     4861 tagtgctaaa cgaaaaaacc gggctctact tttcagagag tccagctttt cttacacctt
     4921 atcgattctt ttgttctatt cttcttccgc catgaatgta ttgaatactt cttcgatcat
     4981 atcccattct gcgtctgttt cgatttgttc taactcgcct tctgttccat cttcgttttc
     5041 gatgtatgca taagcttgta attctacatc ttcatcttct gaaacaccag ctggatataa
     5101 aagaacatag ttacgtccaa attcttcttg tccgtcaact gttagcaaga tttcgtataa
     5161 tgtttcattt ccttggtcat ccaccaatgt gatgtgttcg tgtccttcgt gttcgtggga
     5221 atggttatgt tctgtcataa gattacctct tttcttttta ttattaaaat aattgcttac
     5281 ctgagccgtc taaataattt tgtaaaatca tcacagctgc taatttatcg atgacttttt
     5341 ttcgtttcgc tcttgaagta tttgcctgct ctactagcat acgttctgcc tgaacagtgg
     5401 ttagtcgttc atcttgataa tcaaccggca aggagaatag ttctttgatc ttctctccat
     5461 atgacatgga agcttctgcc cttggtccga tggaattgtt catattctta ggtaatccaa
     5521 ctacaaaacg gtctacttcg tactgcgcca ctaattcctt caaccgatca aaaccaaact
     5581 cttcttctgc ctcattgatt cgaatgattt ctactccttg agctgtccag ccaaagggat
     5641 cgctcacagc aacgcctact gtcttagaac cgacatccaa gcccattact ctcataaatt
     5701 cactccatga tttgagaggt agtctttgac aattacttcc atgatttcat cgcgttcgtg
     5761 acggcgaatc aaatttcgtg catcacgata acgaggaatg taggccgggt ctccagaaag
     5821 caagtagccg acaatctgat tgattggatt gtagcctttt tcttccaaag cccgataaac
     5881 aatcgctaat gtttcgctca cttctttttt gcgactatcg tcaaaaccaa aacgtacggt
     5941 ttcatctgta aaacccatga ttctacacct ctttcccgca aggtaattcc agcttacctt
     6001 ctacaccctt attttactcg aagaaaggga aaactacaaa caaatattcc aaacttctga
     6061 ataaattaag aaacacgatt tgtctgattt ttcctttttt ctgtggcttt ttcaaaagcc
     6121 ctctttccat aaagtatacg ctatatttct ttgaaagtat gtttttacac aattttttca
     6181 taaagttcat aaaaaattcg aattgctgct actaattttt cgttttcgtt gcttgccctg
     6241 tctcataatt gatggtgtag ccatcttgaa cattgtagat aaagacattg aattcaattt
     6301 ttttgtcttc aatgctttct gcttccaact gcacacctct tgctaccagt tcatttccct
     6361 cgaaatgagg agtgacacga tagcgtacat gatgatttgt ttccttgata tatgccgcaa
     6421 tatcattttc gtgggcaagc atgtacggag cattcaacga acgtgtccct gtcattaagt
     6481 ttttaatgtt attattttga ccagtcaact ggaaaccaat caaatggctg cggttgtata
     6541 accattgtcc gtcacttaat ttcttttgtt tccaacctgt cggatcaata tacaaaggtt
     6601 ctctcttttc agtaggaaac aagtcttttc ccaacatcgc attggcttgt cctactctgt
     6661 tcaatttgtc tatatttgaa tagctttccc atgtcccttt ggaaagacta agatcctctt
     6721 ttgtaaactc cggctgattc ccattgattt ctatttcttg atgttttcca tcatattctg
     6781 gcacatccgc tacttgagaa gcttgcggtg tggaatcaaa aatggttgta atttgttgga
     6841 agatatctga atctttttgt gtggtggaaa taccgagtgc ccctgcaatc acagcagcga
     6901 cgatccccac gatcgccttg gttgtttttt tgctcatttc tttactcctt tactaacagt
     6961 tccctaaatc ttaacatatg ttcccctata aataaatact ggaaagaaat agaaacagta
     7021 aaaaaataaa accagttttt agacggctta agaatacaaa aaaagagacg gattcatcgt
     7081 ctctactcaa tcacaaaaca ctatttacaa ggtatttatt atcattcaaa aaatttttct
     7141 taatactcaa aactaaacgg cttctgtacg acctcttggt aaacagtgtt caaaagcttg
     7201 catctgcggt aataagtcca accaagtcaa aaacataaga agcttttttg cttgactatt
     7261 cttattactt gatgcagggc agctttttca cagcctcttt taagcgggtg acgggaatcg
     7321 aacccgcgac atcagcttgg gaagctggga ttttaccact aaactacacc cgcgatacaa
     7381 aaacagtata cgcctctttc actccttcct caagtttttt tattctttac gcttccgata
     7441 tgttttgtag taaaataaaa ctaatcaatc aattattgga gaagatgcta tgacgggaaa
     7501 agaattagat ctgttgctgg acacttgttt actcgctggg aaaatcatga tggaaagcaa
     7561 tgcggagatg tatcgggtag aagatacgat gagtcgaatt gctttagctt ctggaaattt
     7621 ccgtttggtc agctatgtca ctcaaaccgg tctctttatt ggtcttgatc gtacctcgac
     7681 catccgaatg gaacaaatta ccaaccgttc gattaattta gaaaaagtag taaaagtaaa
     7741 tgatctttca cgtaaatatg ttgcttcaga gctaacatta gaagaacttt actgcgaact
     7801 gcaagcaatc gaccgagacc gttctttctt tcctgtctgg ttgcaaatcg ttagcgcggc
     7861 agtgatcagt ggaacaatta tggtgttatt tggcggaaag atgaccgatt tacctgtgac
     7921 tttagtcatt ggaggattgg gatacgcagc ttatctatat agtttgaaat tttttagaat
     7981 caaattttta tcggaatttt tatcttcttt attgattggc atagccgcta tctacagcgt
     8041 acgttttggc ttaggaagca atcaggatct aatcattatc ggatgtgtga tgcctttagt
     8101 tcctggagtt caaattacga acgctatccg tgatttgcta gctggacatt atgtctcagg
     8161 agtttctcgc ggaacagaag cgatgatgac tgctacgatg atcggttttg cgattgcttt
     8221 tattttccag cttttttatt aggaaaggaa cacaagtatg gggacgatat ttattcagtt
     8281 ttcttttagt tttttagcga ctgcggcatt tgccgttatt acaaatgtac ctaggcgttc
     8341 attgatttgt tgtggtcttt ctggtgcttt tggctggatg atctactgga tctgtgttca
     8401 aataggcgga tctgctgctt ttggttcatt gcttggttct ttaggagtag cattcatcag
     8461 cgatcttttc tctaaacgtt tgaaaatgcc cgtaacgatt ttcaatattc ccgggatggt
     8521 tcctctagtc cctggtggtt tagcttatca agcggttcga aatctcgtta ctgaatccta
     8581 tcgagaagcg gctcattatg cggtccaagc aattatgatt gctggagcaa tcgctttagg
     8641 tcttgtatta tcagaagtct ttaaccataa catccgtaat ttcaaagtaa agcgtgacgc
     8701 aatcatgatg aaacgaaaaa aacggctttt taaataaacg aagtgtaaca aagaaaaggt
     8761 tgtgaaagag acgttcagcc ttgagcgatg acaaaatatc tcacaaacat tgcgacaagt
     8821 aaccgcagga gcaataagaa gtaattatga gtattaaaaa aagttttgta aaaatagctt
     8881 ctcacatttt tacataaaat tgacttaata ctgagaaact gacttttgaa caccctctat
     8941 ctgtaaaaaa ggggctgcga catgattttt gtcacggccc ctcttcttta ttcaaatttt
     9001 ttccaaaacg ttcgttgata ataaacgatc catagagcgg aaagtattag aactaaaccg
     9061 atcacaggaa tattcactaa ccaaaatgga taaaacaaag ccaacattcc gtataagacg
     9121 ataagaataa tactgatgat caatgaaccc atcatagttg cgactaaacc caaacttcct
     9181 gaacctctgt taaataattg gttaatattg gtccagttca gcagcagcaa ccgataatct
     9241 ctagcgaaat aacgtagtga caataagtag cagccgaata aagaaccaaa tagcaagcta
     9301 gggataaaaa acaaaggcag ctgaaaagac agtccgctta ataatgcgat cccaccagtt
     9361 aaaaaactct gcaatatcca tccgaatctg aacttttctt ttaaatattg gttcatagag
     9421 attggcaaag aacggataaa cagaaaattt tcttgatcca aagaaataag attgctgata
     9481 aaagaagtct gattaactgt taagaaagcc aatgcgatcc ctaccaggaa aacaacaccg
     9541 attaacttat tatctaaatc agttaatttt atttcgcctc ctagggcaaa agcaagaata
     9601 aaaatgattg gagttaacaa ggaagaagaa agaacttgca taatcaaatt aggttctttt
     9661 actaattgag cattgtaact aaataaaagc tgatgcacat tttggttctt tttatgggtt
     9721 ctttttattt tgaactcact gtttgaatca gtcagttgct ctgtaagctt tggtactatc
     9781 agctgtttta cagcaaggaa aaatcccaga gccgtgatag ctagtattcc ccaacccaat
     9841 aaaccttgtt gagaaagtgg ctgactggca gcatcataga atggcaataa tatcgaaatc
     9901 ggatgccgat ctgttaactc attttcaata gtccccgttt gatgattcat ccacatgatt
     9961 ccagcaaatg cgatcagcat cgagctgcca agcaagatac tagaaactgt ttttctatgt
    10021 tttttaaaca ctgctgttcg agccaaacca aaaacaatca aactagccag acaaaaaaga
    10081 ataatcaaaa atagagaaaa caaaaggatt gagataatga tagtaagcaa aatccctaga
    10141 tcagctcgcc atccggttaa aataaacatg actagaagcg gaaaaacaaa aggaatgatg
    10201 gtcaaagcaa ctaccaaaat ctttgctgaa aaaacctgtt cttgtccaaa aggcagaggc
    10261 aaaaatactt gcaggtcatt tccttcaaaa aagatattat aaatgactga tatactttga
    10321 gttaaaccta acataccaaa aagtgccacg taataagtaa agaaacctgg caatttaaca
    10381 aagttcatag caaacatagc aaatccgtaa atcagtaaaa aaatcagccc tgaaaaaaga
    10441 ttttgagaca aaagatagat agttaatcgc tttccctttt ttcctttctc tcttgcttta
    10501 ttcgtgagct gtggattaac atataaaaga ttaactcgaa ttaattctaa taattgtcgc
    10561 ttatacatac ggtccatctc ctgtcgcttg ccttccagcc attttcaaat aaatcttttc
    10621 tagcgtttca tcaggtgagc cattcaataa ttcactaact gccccctgat aaatcaattc
    10681 acctttcttc aaaatagcca gtttatcgca taactgttgt gcggtatcca atacatgtgt
    10741 agaaaaaatg actgtttttc cttttgcggc atgagccttc atcatttctt tcaaatcaaa
    10801 tgctgcttga ggatcaagtc cttgcaaagg ttcatccaat acccaaatat ctggatctgg
    10861 cagcaacgtg ccgatcaaaa tcgttttttg acgcattcca tgtgaaaaac ttgcgattgt
    10921 ttcattttga tgactataca tatcaaaaag cgctgtcaat tctgctaaac gcttttcttt
    10981 tttttgtgtg tctaattcat aggcagctga aatcaagtcc caatattctc cagccgtcaa
    11041 ttgtaaaaaa atatctgggg aatcaggcac ataaccgatt ttttgtttga tactcaatcg
    11101 attttccgtc aatttcattc catctactaa aatcgttccc gatgatggtt caataatact
    11161 aactaaactt ttaatcgtag ttgattttcc ggcaccatta tgtcctaaaa atccaaaaat
    11221 ttccccttgt cttatcgaga gagacaagtc ttttaatgct tgttttttcc cgtaactttt
    11281 acttacattg atgaattcaa tcatttctgt actccttttg tttgttatta ctttttattg
    11341 tacccttcgt tattggtgga gtaaatgtca aaaagagtgc ataacaaaaa aggatagaaa
    11401 cgactaggct gctacttggg ttgttctctt ctacaggaaa acactcttct aacaggtaag
    11461 atatgagtct ttgttttctt taaaatgatt cattttctat cttttcttgc ataaaattct
    11521 ttagtttatc aatacttctc tttcccatct ctagttgttc tccatttgca aatgttacta
    11581 tttcgtttac tctgctaata gatgtaatgt tttcagtatt aatgatataa gcttttaaat
    11641 ctttacataa atactcatat tcgagtgatt ttttatattt tttaattgtg ccgtttacga
    11701 gaatctcttc atctttcaat actaggccta ttttattttt ataacctggc atgctcatta
    11761 gataaaggat ttcatcgtaa tggatatagt gatcgctatt accataacgg acagttgtcc
    11821 accttttttt cgtagcatgt tgaacaggat agttttcttt ttctttcaat aagtaacttt
    11881 ggatgctttt tttatttttt tcataagtga attcttttat caaataacca ctaggcgtaa
    11941 tctttcgatt aataacagtt attgctttat tcggatgaga cgttagataa acaattttac
    12001 acttttcatt cttttctcta agcatttcgc ctagttcgat accgctataa taggcgttca
    12061 aatcgatgtc taggaaaaaa atatctgagg aatagatttc attattttta atgaattcaa
    12121 caaattgtat aacgttcaat ccctgaacga tctcaaattt ccaaggactt aataaaattc
    12181 tggattcttc caaaatttct actagcattt tttcaaaaac caaactatca tccaaaataa
    12241 atatacgcgt taccataaaa agtacctcca ctcgatattt tactatcaaa atcatttcat
    12301 acaacttttc aacatacatg ttaggaataa attgtaattc tcttcacaat cttttccaac
    12361 acctttgaaa ccgatatcaa atactttcag gatgctgctt ctaaaataaa tatcaaacaa
    12421 atgaatacat catgcaaaaa aagccagaca accgacgtcc ttgcgtgtca gctgtctgag
    12481 ctatgtttat ttattttgtt cttttaaaaa gaacgataca catactgatt tttcggagca
    12541 gagactttct cagcgtttgt aacaactaca gatgggattt cacgcttgaa tggttgataa
    12601 tagtctgatt ggatggttcc ttctatttta taccattcat catttttaac cgttactcct
    12661 tccggcatat gcgtcaacaa accaaagact cctgaatctg ccacacaatg gataatgccg
    12721 aatcggaaca agaagatatc tgtattgcta tcgttcggtg tttggtaaac aaatccttca
    12781 tagctgattt ttttgccaat gaattcgcta gggtaattat aaattagctc cataacttct
    12841 aaatagtttt catctgtgat cttgatagtt tgcttatccc catacttttc tttcaactca
    12901 ttcatttggt ctaagtagtc tgatttgttg aaataaatac tggtatccgg ctttaagtat
    12961 tgtgtctgca tctccggatc ccctactgat tctttactta ctgggaaatt aaatcctttg
    13021 gcttctacga tcgtagtgtc gagactaact gttggaaaca acgtccccac gattactggc
    13081 aaagctagca gtacataagc gattccacgt tgataaggtt ttgacaaccc atggtcatga
    13141 tcgtgctcgt gtgccttttc ttctgctttt ccgtttttga cccacaaata cagctgaact
    13201 aaagccaaaa gagcagataa aatcattgaa agaatagcta agtagcgata atggacattg
    13261 atatattgat cgagtttgcc agaaacttgc aagtacatca tcaattcgaa atacccagat
    13321 aaaatcaaaa accgcagcat attttccctc ctaaataaat aatgtgaatc caataacgct
    13381 aagggcaatc agtccgatca gcgataaaat aaagcgtcct gtaaaatatc gtttcatcat
    13441 cagtagattt ttgatatcga ccattgggcc aaagaccaaa aaggcagcta caggtgctgt
    13501 gccgaacaga cttaacaaag aagatcctat aaacgcatct gcttctgagc aaagagacat
    13561 cgtaaaggcc aataacagca tgatgataat ggctaaaatc tttgttgagc cgagcgttag
    13621 cataattcta gttggtaaat aagtctgcat cgcagctgcg attaatccgc caatgatcaa
    13681 ataacgacct gtatcaaaaa attcgtcgat tgaatgtgtc aacacatgcc cagtttgatg
    13741 gatcagctga ttttttggtt cattcttctc actttgttct tcttcatgga catgatgatg
    13801 gtgattttct gctactttag acgtgatttt ttctttcaat acagcgtctt tttgaaaata
    13861 ggcaagccag acaccaatca caagggcaac aaaaaagctg cctatcaccc gccagcttgc
    13921 catctgccaa gaattgccaa atgcgataaa agtggaaaaa atcacgattg gattgatgat
    13981 cggagcagtc agcataaaag caaacgctgt gtgaactggt acgccttttt taacaaattg
    14041 atgaacgatc ggtacgatgc cgcattcaca tgaaggaaag aaaaatccta agatcgaacc
    14101 agtaaaaata gagaagatac gattttcagg aagccatctc ttcacacgtt ctggggtcaa
    14161 aaatacttgt aaggcgcctg agataagaca gcctaataat acgaaaggta atgcttcaat
    14221 aacgatcgat aagaaaatcg tactcatctg caaaaccgaa tttggaataa aagaaaacat
    14281 gagtttcctc ctttttattt ctagttcatt cgctttgcaa atatacgctt ttattcaaaa
    14341 aaaacaagtt gctctgtaaa tttttacaca actcttattt tttaccaaag cacttcaatt
    14401 gactttttct gttattccca ttaaattaag gtctcataca tatcacttct atcataaaag
    14461 ggagaataaa aatgaaacaa accactaact tgactgaagt tcaagacata ctgcaacagt
    14521 catccgttgc cgtcatttat ctttcgatgc ctaattgcag tgtttgtcac gctgttcgtc
    14581 cacgactaga ggaacttctc acacattatg atattccggc acttcatttg gatgcatttg
    14641 aaacaccaga agtagctagt aaatttgaag tgctgactgc gccagttgtc ctgatttttc
    14701 atcaaggaaa agaagtcttt cggcaagcac ggttcatcga ctttaaaaaa atccgttatc
    14761 tactagatga actgacagca gaagatgatt ccctttctta tgaagaaatc ttccgaacaa
    14821 aataatcgtt gtccaaacag aaaaaagcga ttgaacaagt gaaagttttg ccttcatttg
    14881 ttcaatcgct ttttattttt attctgctgt attttcggaa tgcgcatttg cgtcagaatg
    14941 caagaaatag atcaaggttt gcaattcatt cgtcaaatca acattttgga tcaatacatc
    15001 tgacggagca ttcaatcgag cagcggtaaa gttcaagatt cctttgattc ctgcttccgt
    15061 taactgattg actacttctt gtgctctttc agcgggtatc gttaaaattg ctacttcgat
    15121 ttgttggatc ttgatttgtt ctgacatatc ttccattgga taaacgggga taccgtctac
    15181 gatgcgccca acgatttcct cattcacatc aaaagcacaa ctgatacgta tgctattact
    15241 ttgatggaat ttgtatttta gtaaagcact tcccaagttc cctacaccga tcagcgcaac
    15301 atttgtcaat tgatcgtcgt ttaatgtctt tgcaaaaaag tgcataagat cttctacatc
    15361 ataaccatac ccacgttttc ctaattcgcc aaaataagaa aaatctcgac ggatcgttgc
    15421 actatctact tgaacggctt cacttaattc agttgaagac acttttttct ttccagcatt
    15481 atttaaaatc cttaaatagc gataatacaa aggcagtctt ttagctgtcg cctttggaat
    15541 aatatgatct ttcacgaaat gacctccacg tattgtctaa ttacatcttt gatttctcca
    15601 tcatagcagt atttatagga aaaaatcaat tccattgctc agatattgtg aaattttatt
    15661 ctttattcat ttatttatca tttctgcaaa tctcgcagta taatggaatt tatggtagac
    15721 tactaattga aaaatagttt tttatttgag gagaattcac aaagtagaaa agaggattcc
    15781 atgatattat tacaagccaa tcagattgct cgccattttg gtgcagaagt cttatttgaa
    15841 aacatacatt tagaaatcag tacaggcgct cgtgtcgctt tagttggcag aaatggcgct
    15901 ggaaaatcga ctttattaaa gatcattgct ggaattgaag cacctgatga aggaaagatc
    15961 gctaaaaata aaacagcgac tctcggatac ctcgctcagg acacaggact tgattccaat
    16021 gaaacagttt ggaacgagat gctgaaagct tttgaacaag ttagacaaat ggaagagcgg
    16081 atgcgcgagc tagagatttt cattagcgaa ggtacgccag acacacctgc ttatagttct
    16141 tatttaaaag aatacgaccg gctgcaacac gatttttcag atcgaaacgg ctatggttat
    16201 gaaaatgaaa ttcgttccgt attgcatggg tttaaattcg attcttcatt ttatgatcag
    16261 aaaatcgata ctttatcagg cggacagcgc acacgtttag ctttagctcg catgcttttg
    16321 caacaccctg acattttgat tctagacgaa ccaacgaacc atttagatat cgagacactt
    16381 tcctggcttg agaattatct gcaaagctat actggtgcat tattgattgt ttcccatgac
    16441 cgttattttt tagataaagt agtcaatgaa gtctatgaat taagcagaag aaaaatgcgc
    16501 cattacaaag gtaactattc gaaatatcta gatttgaaag cagaacagtt agcaagtgaa
    16561 tggaaggctt atgaaaagca gcaaacagaa atccataaat tagaagactt cgttgctcgg
    16621 aaccttgttc gcgcctctac cacaaaacga gcgcaaagcc gcagaaagac attagaaaaa
    16681 atggaccggc tggatcgtcc tcaaggggat gaaaaacaag caaactttct attcagtata
    16741 gaaaagcctt ctggaaatgt agtcttgcaa atcgaagatg ccgctatcgg atatgataat
    16801 gtcaccttat ctgaaccaat caatctagat atccgtcgtc aagaagcgat tgctctagta
    16861 ggtccgaatg gtatcgggaa atcgacgttg ctgaaatcaa tcattcacca gatccctttt
    16921 atccgtggaa aagaaacgct agggacaaat gtcaccatcg gctattacga tcaaggtcaa
    16981 gctgatctgc atacaaacaa gacgatccta gcagaattgt gggatgagca tcctaccact
    17041 ccagaaaaag agatccgaag tgctttaggt gctttcttat tttctggcga agatgtagaa
    17101 aaaccaatcc ctctgctaag tggcggtgaa aaagcacggg ttgctttagc caagttagcg
    17161 atgaacaaag aaaatttttt gattttggat gaaccaacaa accatttaga tattgacaac
    17221 aaagaagtat tagaaaatgc attgatcgat tatgacggca cactgctttt tgtttcccat
    17281 gaccgatatt tcatcaatcg gatcgcgaca aaagtcgtcg aactctctga aaatggcagc
    17341 aaagtctatc taggagacta tgattattat ttagagaaaa agcaggaaga agaagaaatc
    17401 gccgaattgt tggcacaaga tgagccagaa tctgctcctg ctcccacgaa caaatctgat
    17461 tattaccaaa gcaaagaaca gcaaaagctt atccgtagcc ttcaacgaaa aattactcag
    17521 gttgaagaag aaatggcgcg gatcgatgaa tggatcgatc agttggaaca agaaatggtc
    17581 gcgccagaaa acctggaaga tcacgtaaaa ctcaatgagc tgaaccaaga tttagaagct
    17641 gctagacaag atcaagaaac aaaattgacg gaatgggaag aactaagctt ggaattagaa
    17701 gaatatgaaa attaacgaaa aaaccaaaac agaaaccatt catgctgttt tggtttttct
    17761 ttttttattt tatcaaacaa aaattccata tttacctttt tcaccaataa gaagaccaat
    17821 tactagtcat tctcactaaa gcttctaaat aatagtaatc accccaaata caaggtgtat
    17881 ttaccccatt atttttgggc ttattataaa cagactgtgt taaaaagcca tcttcttctt
    17941 ccgttgtagc atatctttct ttcaattgtc gcataatttt ccaaacagca gactggtata
    18001 agttcttttc tgttttgtct aatagacctg attctattaa ttctaataat ccacaaacca
    18061 tgatcaccat actagatgta tctttttctt ctctgctaga atcatcaaag atcaaatccc
    18121 aataacaaat ggtatcttct ggcaaccgat tcataaaata attggctaat attttgctta
    18181 aatcaaaata tttttgttct ttcaaataac gataacttaa tgcaaaaccg taaatccccc
    18241 atgcttggcc tctagcccaa caggaattat cactataacc ttgatgcgta cttccatatc
    18301 ttggttttcc atctttgaca tccatataaa atgtatgata agttgaacca tcttctctta
    18361 ctaaataatc tgctgcattt tgaatatgag cctgagcagc ttttttatat ttttgatttc
    18421 cagtttcttc actcgcccaa tacaataatg gaagattcat gcaacaatcc atgatcattc
    18481 taccttgttg tgaaggatca ctaggatctc cccaagcttg tataactcct gccttctccc
    18541 aaaaacgctg aagtaatgtt tctgcagcat caattgaagc ttccttcatt tttcgatttc
    18601 ccgttatttt ataatctgct acggttgata aagaatacaa aaaaccaaga tcgtgatgat
    18661 tagtgataat ttgacagtca atcctgtgga taaaatctat atctgctttt tcagctgttt
    18721 gttgaaataa aggatcaccc gtcttctcaa ataacaacca attaattcct gtccaaaatc
    18781 cttctgtcca accaatattg tctcttaatg gataacgtcc ttttatagga cactcgcttg
    18841 ggaattgata ctgactgtta ctgatacgtt tgattaacct ctccgtgtgt ctgcgacaac
    18901 gctcgatctc attattccat tctttttcca ttaattcttt ataacattca tttatccatt
    18961 tttctggatg tattatctct tcaaacatca ctttatcaag catttcccca ccagccttta
    19021 gcataatttt agtctttttt tattgttttt attttggata gttagcccgg ttgtcccatc
    19081 aaaatcaatt ttgggacgat tgttccatac ttctaaacta taatcccgat cttgatgagc
    19141 aaccactcct gttccgagcc aatgggttcc ttttccaaat gtaccctcta atccaggaat
    19201 aaaagtgttt tcccatgtca tcaagtttgt attgggcaaa cccataatag ctgtggattt
    19261 tcgtttaata gtatcgtcac ttaaacagat aatacctgaa aagccagctt cactcaccct
    19321 atagttttcc ttgtcttctt ctatgattat tccttctttc tcaggagaac attcaatagc
    19381 aaaccctgtc tcatatagaa catattctgt atctaattct actttgtgta cgcgaatctg
    19441 ccagccttca aaaggaataa gccaagttct gatttttgcc tgtaaagtag gttcccatgt
    19501 agaggcaagt acctctttct tacatacaat gtctcgtaca ttatttcgaa cgatgaactg
    19561 tccataggtt ttgatgctct cattcttaaa actggtcgtg atatatgtgt ccgctcgctg
    19621 aatccctagc attgaatcca ttgccatttc tgctttcaat tgattcgctc gcggtatcga
    19681 aaaaccaaat tgactagaat aagcaaattt taaatatttt tcattggtca atgtatggaa
    19741 atttggccct aattgtcccg cattcaaaaa aaatgtatgt ccattatcat gttgtatgag
    19801 caaattggct tctgaaagaa gtttagttcc ttcacgaata ggcataggca tttctttagc
    19861 cgtccaatac tcatggtctt caggtagcgc caacaataaa aaaatcttat tcagccataa
    19921 tggagataac gtactattat agggttcagt caatgtcaat tgagggtagg tataaccaat
    19981 attcaggata cctttttcat caaatatttc tttttgcatc caccatctta tattccgatt
    20041 gactaacccc ttgatttcac ctaatttaaa aggcaaaaga tcggcccaca acatagctga
    20101 ccaaaagctt gaaactgcaa aacgataaat catgcttcga ccaaaaggca catttgcacc
    20161 atcttccgca aaaaaatgaa tatagtctct agaaaaatca atagctcggt tcttatatat
    20221 ctggctaatg ggcttttctg gttctagtac gctataaatc aaaccataat aatgaaatgc
    20281 aaaaggatta taataatctt ggcgacctct tgaactgtct cgataccagc cattttgaag
    20341 ataacaattt tctatattat caaatgcttc tttcagtgct gattctttaa ctggataacc
    20401 aaatttttgg ataattgttc cgacaattat cttaaaaaat tgccaattac catctgcaca
    20461 ttcatattca aaaatttgcg agaaccaatg aataatctgg cttttttctc ctgtatctaa
    20521 ttttttccat aataattgtt catgatgata taacgctaat aacattgcgg gcatttctac
    20581 catacgctgg tctctttcat gtatttctcc ccaataatcg ggatgggaag gatctgttcc
    20641 agcttttatt cctgatagaa ttaatttcaa ccatcgttca tctaattggt caattgcggg
    20701 ccccgctccc cataaaaccc gagagaatcc ttccattcct gcaattttat ttccatatcc
    20761 taccccttga tgtatataat caatttgtgc gccacttgct cgataaaacg gctggagtgg
    20821 ttgatttatc tttttaaata agtcaaagta atcctgtctg gtccttaata gtggtactgg
    20881 atgtttcatt gtattttctc ctctttttac taccaaatag ctaattccga ctgttctaat
    20941 cgaagtaagc cttcaataaa aaaataatca gaatagatca gtggcacatt ataagtcagt
    21001 tctctatggt atgcttctgc tccgcctcca atgatcccat cttcatccat attccaattt
    21061 gcatagtgct tttctgtctt ttggagtata ttgatagcag cttcatgata catttttgat
    21121 cgtacagagg aaacatatcc tgctaattcc agaagaccgc atgcagcgca tactccagca
    21181 ctggtatcaa tattcgaatc ttttacagca aaatcaatga gaggaatata accagttttt
    21241 tcgattttct gaataaaatt tactgctatc ttttctgcta tagctagata gtacggattt
    21301 tttgtgtaac gataacttaa cgcgaatcca tataaagccc atgcatttcc tctgctccaa
    21361 caagaattct cattgtatcc ttgcccgcca agtaaccgaa tatatttccc tgattctgca
    21421 tcaaattctg cgatatgccc ggttgatcca tctttcctca ctagatactt agctgttgta
    21481 tctgcatgct gccgagcaat tttagagaac ctcggatcac cagtttccct cgaagcccaa
    21541 tacagtaatg gtaaattcat catactatca ataatcatcc aaccaggttt atggtcattc
    21601 catgctacta aatagttccc tgaaatatta tagcgtccag caagtaccgt agctgcatgt
    21661 aaccctagtt gtcgactatg tttgttttga gactgttgat aatgtgcaat agccgatggt
    21721 aagaataaaa aacctacatc atgatgaacg tctgaaaaat ggtacagggc agattctaat
    21781 aattgttctt gttgtattgc tgcctctttg aacttttctc gttttgtctt gtgaaagagc
    21841 tgccataaaa taccactcca aaaaccattg gtccaccagt cgattcctct gtcctttatt
    21901 acgtctgtat attttccgtt gtaagaaata tatggaattt tattccccat tctgtctaat
    21961 tccgcatcta tcttttcaga agctacattc aaaatttttc ttgaccattc cttcgtctgt
    22021 tcattcatgg atatcccgcc attcttttaa tttttatgaa tgtggagttg ctcctagaac
    22081 gaactagatg gttaacattc gttatttttt ttacttattt gcagctccaa tgtcattctc
    22141 cttaaattta gactgcgccc acacataaat caagaccatt gggatcactg aagttgctaa
    22201 aattagcata attgcgccat aattaattgg ctcacctgta ctagaaaccg tcatattttt
    22261 gataattaag ggaaccgtat atttatcttt atctgaaagc atgactaatg gaaatagata
    22321 ttgattccaa cttcccataa agataagtaa accactagta ataatcgtag gtgataaaat
    22381 cggtacagcg attttcgtaa aaatcaccca ctcattggca ccatcgattc tggcagcctc
    22441 catcagtgct gtaggaaatt gactgctata ttgtcgcatc ataaacactg aagttgtact
    22501 ggcaatcgaa gggatgatca cacctgcata agtattcgat aatcctaaac gactcataat
    22561 gtaaaataaa ggaatcaatg tggtaaaaaa aggcaccatc ctagatagca taactgtatt
    22621 gaacaacagt ttattcccca taaaacgata ctttgctaat gcataacccg ccattgtaga
    22681 actggctgta gctgaaactg tactgattac agcaataaca atcgaattcc aaataatcaa
    22741 gggataatta tatctcgcca tgatggcttg ccagtttttt aatagcatat ccccaaactt
    22801 gaaattgatt ccgccactta aaatttcttg attactttgc gttgaagcta caatcatata
    22861 taaatatggc atcaaaaata ttaaggcacc aaacacaata atgacgtacg taaaaattct
    22921 gctttgtatc ttttgtttag tcatttttat cacctccgaa tttaaattga atagccgata
    22981 atataacaga tacaaacacc atcgtccagg caatagcaga ggcttttcca aaatcaacca
    23041 tttcaaaact tgttttatat aaattgactc ctacgaccaa agctgaattt tctggtccat
    23101 tggaagtccc aaagaatata tttgggatat tgaaattacc caagccattg atagtggcta
    23161 aaactgtggc cattaaaatg attggcttta gcatggggat cgttaataaa aagaattgcc
    23221 gaaatttcga tgctccatct atttcagcac tttcgtatat ctctttagaa atcccttgaa
    23281 gaccagctaa aaataaaata gtgttatatc ctacactaag ccaaatcatc gtgatgatca
    23341 ttgatattcg tatccaaaaa ggatttgtta accactgtac accgttaatt cctagcgcat
    23401 tcaaaaatcc attgaataac ccagtcggat tgaaaaaagt catgaatacg gaagctacag
    23461 ccaccgttga tgtaatggtt ggaatataat agacagttct aaaaaatcct tttcctttta
    23521 actgtgctga attcaataaa acagcaaagt aaatagctaa tagcatcgtt attggaattg
    23581 atcctgccat gataatcaaa acattcgtgt aagatttaat aaacaatgga tctcggaaga
    23641 tagctagata attgtcaaat ccaacaaatt caaatgagta gccaattttc ataaaactaa
    23701 aagcaaacga gataatgatg ggaatcaaaa tcgtcacaat aaagaaaata acaaaaggtg
    23761 tgaccaatcc ataagcactt tttttatgag acgtatctgt tgcttttttc ttgctgttct
    23821 ttattgtctt gcttggtaac gaagattgca tcatcgttaa gtcctcctaa tattttttaa
    23881 tcaccagtta attttacgcc gtacttatga gcaaaatttt ctgcttcttt tagatatgaa
    23941 ttttcaaaat cacctgtttg ccaatagtta tatgcagcgg tagtcaaata agacgtagca
    24001 tctgaataag tggctggtaa aacagtattt gatgtatttt cattgatttt attcaatagt
    24061 tcatagtatt tttgtcctcc ttagtagtca aactttttct cagctgcttc tgtttgatag
    24121 gccaatgagt tagatgtagc cacgcccagc tccagtgcgt tggctaagca ttcttcatct
    24181 gtcagcataa atgtaagaaa ttgttgtgcc acttgtggat ttttggcatc tttagggaca
    24241 taaaaacttg atcctcctga tactgcacct tttcctggat tttcttttga aaaaggaatc
    24301 agtggagcca tgcgccattt gtcagatgca tcaggaaaat tcaaagacat attcgtagca
    24361 taccagccgc cagcaacaaa cattgcagat tcttgaaatg ctttctcagc atcttgtgca
    24421 ccgtagaaat gtacaatatc tgagtcgatc atttctttga ttaactttgc agcatgtttc
    24481 gcttctttag tattcagacg gatatttcct tcttcatcaa gcaaagattg attctgctgg
    24541 gctagcatgt tgataaacaa ttcttggtcc ccagattctg gcaaggcaat tccaaaacta
    24601 ccagtttttt cttttaatgc ttttgccacc tggatatatt cttcccaaga actgatttct
    24661 tcaaaatcta cacctatttc agcaaatttt tttggttgat aataacaaag tgctggggta
    24721 aaatcactag cccaaggaat aatcgtttca ttactcgttt gttgacgcaa aatattcaat
    24781 ttttgatcat aaaactgatc gccatatttg tcataaaatc catattcatc agcactataa
    24841 aaagcatctt gaaatttttc cagcacacct gctgctgaag tgtctgccat ggagataata
    24901 tccggcatat cttcgtgtgt taccaatttt ggggtgatca tttgtactgt tgctgttccc
    24961 gaagctacat tcacaatttt taagtcaata tttgctccag ttttgcggtt atagattttt
    25021 gcagcatttt caacatagtt tgtcagtttg ccgtttgcga catatacttc taatgtagtg
    25081 gcttttttta tcattggatc tgcgatgttt gctgttactt cttcgttagt ttttccacat
    25141 gcacttaagc tgaataatag ggtaatgttt agcaaagcta tcaccaattt gtatcttttt
    25201 ttcatgtcta tcccttcttt cttttcaagt tcttat
//
LOCUS       DAZKCH010000035        25216 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000035 DAZKCH010000000
VERSION     DAZKCH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.035"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(164..388)
                     /locus_tag="ACG84X_001468"
     CDS             complement(164..388)
                     /locus_tag="ACG84X_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFP9127343.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="ACG84X_001469"
     CDS             complement(586..2166)
                     /locus_tag="ACG84X_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFP9127344.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="ACG84X_001470"
     CDS             complement(2567..3943)
                     /locus_tag="ACG84X_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFP9127345.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5159)
                     /locus_tag="ACG84X_001471"
     CDS             complement(4071..5159)
                     /locus_tag="ACG84X_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9127346.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="ACG84X_001472"
     CDS             5331..5765
                     /locus_tag="ACG84X_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9127347.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="ACG84X_001473"
     CDS             complement(5843..6376)
                     /locus_tag="ACG84X_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFP9127348.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ACG84X_001474"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ACG84X_001474"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFP9127349.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ACG84X_001475"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ACG84X_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFP9127350.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="ACG84X_001476"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="ACG84X_001476"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFP9127351.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="ACG84X_001477"
     CDS             complement(10101..10679)
                     /locus_tag="ACG84X_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFP9127352.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="ACG84X_001478"
     CDS             11001..11471
                     /locus_tag="ACG84X_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFP9127353.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="ACG84X_001479"
     CDS             complement(11579..12805)
                     /locus_tag="ACG84X_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFP9127354.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(13559..13759)
                     /locus_tag="ACG84X_001480"
     CDS             complement(13559..13759)
                     /locus_tag="ACG84X_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9127355.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(13893..14501)
                     /locus_tag="ACG84X_001481"
     CDS             complement(13893..14501)
                     /locus_tag="ACG84X_001481"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFP9127356.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(14586..15056)
                     /locus_tag="ACG84X_001482"
     CDS             complement(14586..15056)
                     /locus_tag="ACG84X_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFP9127357.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(15104..16018)
                     /locus_tag="ACG84X_001483"
     CDS             complement(15104..16018)
                     /locus_tag="ACG84X_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFP9127358.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            16164..16967
                     /locus_tag="ACG84X_001484"
     CDS             16164..16967
                     /locus_tag="ACG84X_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFP9127359.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            17145..18092
                     /locus_tag="ACG84X_001485"
     CDS             17145..18092
                     /locus_tag="ACG84X_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFP9127360.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(18160..18453)
                     /locus_tag="ACG84X_001486"
     CDS             complement(18160..18453)
                     /locus_tag="ACG84X_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFP9127361.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(18481..19146)
                     /locus_tag="ACG84X_001487"
     CDS             complement(18481..19146)
                     /locus_tag="ACG84X_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFP9127362.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(19286..19918)
                     /locus_tag="ACG84X_001488"
     CDS             complement(19286..19918)
                     /locus_tag="ACG84X_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9127363.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(19925..20992)
                     /gene="liaS"
                     /locus_tag="ACG84X_001489"
     CDS             complement(19925..20992)
                     /gene="liaS"
                     /locus_tag="ACG84X_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFP9127364.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(20989..21720)
                     /gene="liaF"
                     /locus_tag="ACG84X_001490"
     CDS             complement(20989..21720)
                     /gene="liaF"
                     /locus_tag="ACG84X_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFP9127365.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(21889..22368)
                     /gene="greA"
                     /locus_tag="ACG84X_001491"
     CDS             complement(21889..22368)
                     /gene="greA"
                     /locus_tag="ACG84X_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFP9127366.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(22504..23679)
                     /gene="mltG"
                     /locus_tag="ACG84X_001492"
     CDS             complement(22504..23679)
                     /gene="mltG"
                     /locus_tag="ACG84X_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFP9127367.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            23883..25052
                     /locus_tag="ACG84X_001493"
     CDS             23883..25052
                     /locus_tag="ACG84X_001493"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFP9127368.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
BASE COUNT         7575 a         5087 c         4060 g         8494 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaaat ctaaaaactt
    13501 cataaataga caaaaagaca cgactctcta agaagtcgtg tctttattca acaaattatt
    13561 ataatttagt cacttcagca gcttgaggtc cgcgtgcacc ttcaacaatc gtgaattcta
    13621 cttcttgacc ttcttctagg ctcttgaagc cgtctccttg aattgctgag aaatgaacaa
    13681 atacgtcatc tccgccgtct actgtaataa acccaaatcc tttttcattg ttgaaccatt
    13741 taaccgttcc gtgttccata aatgtatatc ctccaaaaaa gttcttgcaa gtaaccttgc
    13801 aagaacatta tacccaattt agaaaacgct agcaagcttt cgctctttta ttttccaaat
    13861 tatttttaag actgatatga cggaggaaat ggttattttg ctgcttcgaa acgtttgttt
    13921 acttcatccc aattaataac attccagaat gctgcaatat aatctggtcg gacattttta
    13981 tatttcaaat aataagcatg ttcccaaacg tccaaaccta gaattggtgt ctttccttcc
    14041 atcaatggag aatcttgatt tgcagtagag gtaatagcta attttccatt ttccattaca
    14101 agccaagccc atccagaacc aaatcgtcca gcggctgctt ttttgaattc ttctttaaaa
    14161 gaagaaaaat caccaaaagc ttcattaatc gcttctttta tttctcctgt aggttcgcca
    14221 ccagcatttg gtgccatgat ttcccagaaa aatgaatggt tagcatgtcc gccaccattg
    14281 ttacgtacag ctgtcttgat atctgttgga atagcgtcca tatcagataa taattcttct
    14341 attgtttttt cgcctaattc tgggtatttc tcaattgctg aatttaaatt cgtcacataa
    14401 gtattgtgat gcttatcatg atgcagatgc atcgtttctt cgtcaatata aggttccaat
    14461 gcgtcatatg cataaggtag atctggtaat gtgtaagtca taaaaaaatt cctcctcaat
    14521 gttttcttaa taatgtctac attacaaaga gtaacaaaga gaaggaaatt cttcaattgt
    14581 tatgcctagt cgtctttttc actttgacct acttcttctt caaaaacctc agtttcttta
    14641 aaaataaaca acttgctgaa aatatagttc gcaaggataa caataatttg agtgatgatt
    14701 ttcgccacat actcattgct gttcataaca ttgatcaaca ataccattgc ccccatgtcc
    14761 aatccgtaag aaaggatacg gtagaagaag aacttaccgc attcaataag tgcatgtgta
    14821 aaattcggtg attttgaatg gaatacccaa agtttgttcg ttacaaaagc aaacaataca
    14881 gaacaaaacc acgaaataga attggataag gccatactta aatcaaaata ttggcgtgcg
    14941 agagcaaaac taacaaaatt tacaatcgta gccaaaccac caaaaaagag atagactagt
    15001 atctcccaat atccttttgc ttctaaatat ccttttaact gtcgatactg cttcatgagc
    15061 caacctacct tattaaaaat tcttatttat catactctat atttcaataa ctttcatctt
    15121 tatttaaaaa aattaatttt ttttgatcct ttgcctttgt ctctgcttgg atcgtcacat
    15181 gtgtaatacc atattttaat tttaataaag aaattatacg aggatatatc ttttcaatct
    15241 cgcttagtag ctgatcttca aaatcaatat gtccgtcgaa aataattatc ttttcgctat
    15301 actgccaaat atggacatga tgaacatcct ttaccccatc gattgcttca atttcttgtt
    15361 ccattttttc atagtcgata gcaggtgcac tttgtatcaa aatagcggca gcttttttga
    15421 tcaccattat cgcttctatc aatatatata tcgaaatgat cagtgtaata actggatcga
    15481 tccagtagat atcgaaaaaa cggatcaaaa ttgctccgat aatcacactt accgaagaca
    15541 gtgtatcact taacaaatgc aaataactag attttatatt caaactttca tctgcttctt
    15601 gtcgtaataa taatactgag aacaaattcg cgagcaatcc aataactgct actgttagca
    15661 tcaaatgact atttatcttt tctggtgaag tgaaccgctt gaatgcttca acggttaaaa
    15721 acaaggataa tatgatcaat atgaatgagt tgatgaaagc actcaatatt tctaaacgct
    15781 ggtagccata cgtacgtttt ttatttgctt cttttcgggc cattttttgt gccccgtaag
    15841 aaaaaataat tgccaatgta tcactaaggt tatggaaagc atctgaaaca agagacaaac
    15901 tccctgacat aatccctcca ataaattctg ataaagtgat caccgcattc aaaaccacta
    15961 ctccaaatag tttttttgat gatctctgtg gctgtgtagg cactattcct tcctccattt
    16021 tatttatatt ggatagtctt tagacaagaa taacattttt ttgatatttc accaatcatt
    16081 cagctgtttc cttaaagcac ttgtatttca cttgatactt cgctagaatt gcaagtgatg
    16141 acactactag atgaggagta cttatgacaa caaaacaatt aattatcagt tcctttatac
    16201 gattcaaaga cctaaaggag gcgagaaatg tcccattttg gaaagccatt gtctatcttt
    16261 tagttttgag tataattatg gctttgccaa tctcttttca agtttttcaa gtcttaaaca
    16321 acattcaatt ggatgggcaa aagattgcta ctcgcattcc tgattttaca atccaaaacg
    16381 ggcagcttca aaccgaagaa aaagaaggat tcatttacca aacaaactcc attatcttca
    16441 catttgatcc agagggaaaa cgaacagaac aggacatctc tactgatttg atggggaatt
    16501 ttgttagtgt cgggatgtta aaaaacaaac ttatcatagc tcttcctaat acaggcacga
    16561 cttctgcttt gttgaacaat aaccaattag aacttcccta caccaatgaa tctttaaaaa
    16621 acttaacagg taagcagctc cgttcttttt taagtgaagc atctatacca ctttggataa
    16681 aagtcctgac atttatattt tctatttatc ctagttttct gaatctgctg atcactttgc
    16741 tatttaccaa cattgctgct tttctctatg cacgctttcg actaacaaaa gctacttttc
    16801 ttgattgttt aaaaacattg atctattcaa tttcattgcc tactataatt gcaacaatct
    16861 tgatggtctt tcttccttct tttgacacta gcgccttcat tgcttttgca ggaatcttta
    16921 tttttgctca agctgtcaaa ggatgggcaa aaatatcgat caattaagaa ataaagacaa
    16981 ctcgttattt ctacttcaat agaccctttt agaggttgtg acattttttt gtcacagccc
    17041 cttttttatt tgaaaaatat ttctttctca aaaaacaagc aaggcgcttc aaagttcttc
    17101 ttgtatgcgc tacacttaga gtaaagaaag gcgggaaatt aactatgtca gaaagaatca
    17161 tttatgcaga tcgtccattt cgtgatgaat ttatcgaaga aatccatact atagcgcctg
    17221 gttatatctt taaaacagaa ttacaaccag aggatctaca aaatgtagag atcagtttgg
    17281 gctggaactc agactaccaa gaaaaactat tagcctcttc taccttgaaa tgggtccaat
    17341 ctatctcagc tggtgttgat cagctacccc ttgagacttt ttcaaagaaa catattttac
    17401 tttcaaatgg tagtggcatc cacagtgaat cgattacgga gcatgtctta ggaatcatcc
    17461 ttgggtattc tcgtggtctt tttcaagcac aaaaggcaca gagtgacatg aaatggttag
    17521 gttcatcggt ccattaccaa tctatccaag ggaaaaaaat actaatcatt ggaactggcc
    17581 atattggaaa aatgattgca aaaaaatgca aagcattaga catgaactgc tatggaatca
    17641 atacatccgg tcatccagca gaaggaatgg aaaagacttt ttctttaaat caactaaagg
    17701 aagttcttcc tgaagtagat ttcgtagtca atatcttacc tctaacggag gaaacaactg
    17761 ggctctttga tcagcatatg tttgaacact ttgatccaaa atctgtattc atcaatgttg
    17821 gccgtggtgc ttctgttaag acacaagatc tggtgcaggc tttaaataac cagcaacttt
    17881 cctttgcagc attagacgtt tttgaggaag agcctcttcc acaagatcat cctctttgga
    17941 aaatggacaa tgtactgatt acttcccaca ttgcaggttt gacacctgat tttcaaaaga
    18001 aattaatggc tattttttta accaatctga aaagctactt tgccacccat gagcttcaaa
    18061 ccaatcaagt aaaattgtct gcaggatatt aatagctgaa aacaatattt tcaaaagaaa
    18121 aaagagaagg tgacaaaaat tgtgtcaccc tctctttttt tattgttttt taaagtgata
    18181 ggttggctcc tccaggttgg gatcataatc aacaagtaaa tcatatcctt taaagaacca
    18241 ttcatctgct tcctcgataa aaaaaagtgt cccatcaatt tccactttct ttacaggatg
    18301 ttctggctgt tcaactgaca ttccaatcga aaaaccatca tgaacctctg ttttgccgta
    18361 gacttttcca aaaaaacgta ttccgtaagt ttctggcaga tcaatttctg agtcaaacca
    18421 cttttgtgct tttggcgtta ccgttaattt catcccaaca acctactttc tcttttcttt
    18481 ctattgattc atcttatcgt ctagaatatc cacatcgcct gtctctccaa taaccagtag
    18541 attatcattt tcacgaacat attcatctgc tgcaggagaa gcgataaccg tttgatctac
    18601 tcttcgtatg gcgactactg ttaagtcaaa acgttgcctg aaatttaatt cagctaatgt
    18661 tttgttgaaa aatttaggat tggagactcg gatttctgct aaagaatatt tatctgacaa
    18721 ctctaggtaa tctaaaatat tctttgacac taaattatgc gcaatcctta ttcccatgtc
    18781 tcgctcggga tggacgacgc gatcagctcc gatcttttca agtactctgg catgatactc
    18841 attttgggct tttgctaaaa tatttggtac gcccatttcc tttaccatca gagtaactaa
    18901 gatactggct tgaatatctt ctccaatagc gacaattaca tgatcgaaat ttcttatgcc
    18961 taatgatcga agtgtcattt catcctgtgc atttgccaca acagcatgag tggctatatt
    19021 catatattca ttgacccgat cttcattact atcaatagcc agtacttctt gaccagcttc
    19081 gatcagtgtt cggcagatac ttccgccaaa tcgtccaaga cctacaattg caaaattttg
    19141 tttcaccgtt ttcctccttt agtatcttct tttctcagta taacaaagcc tttacaaaaa
    19201 caaaagcaag catcattatt gtaaaaaagc caagaaaaat aatagttatt ttctcagctt
    19261 ttgattatcc tctttatcat cgtttttatt tcaccaaacc atgtttgaat gcatagatag
    19321 cggcttgtgt acggtcttcc acttctagct tagccaatat attggaaaca tgtgttttta
    19381 ctgttttcag tgtaataaac aattcgtccg ctatttcctg attacttttt ccttcagaaa
    19441 tcagcattaa aatttcattt tcccgattcg ttagttcttc atgtaataca ggctcatttc
    19501 gccgactcat tttttccatc atttttgttg tcacttctgg ttctaatact cgctcgccac
    19561 gttgcgttgc ccttatagca tcagcaattt catgtgcggt agaggtcttc aacaaatacc
    19621 ctgctgcacc tgcttcaatg gcaggataaa ctttttcgtc atcaataaaa ctggttacga
    19681 taatgatttt agcttctggc caatctttta agattgcttt tgttgattcg ataccatcca
    19741 tttcttccat gactaagtcc attaaaatga cgtccggtcg aagtgtcatc gccttctcat
    19801 agccttgtcg tccattttca gcttctccaa ttacttcaat gtcttcttga atagataaat
    19861 aaaaagagac gcctaagcgc accatttcat ggtcatctac taataaaact tttatcatcc
    19921 ttatctatgc ctccttcatc aaagggacct tgatttctac acttgtacct tgacctttaa
    19981 aactaatgat ttttactgtt ccaccaatac cagctactcg ttctttgata ttgttcaatc
    20041 cataacttcc cgttttcgtt tcattcatat taaaccctgt tccgtcgtca ataatacgta
    20101 acaaaagatt attgtctatt ttgtgcaaat atacctctaa ttcattggct ttagcatgtc
    20161 ttaatgtatt tgataacaat tcttgaacga ttcggaacaa gtgatcctca atggaactag
    20221 atagttttac atcttctaca tcccatttca gcgaaatctg gattttattt tgcaattcct
    20281 tcaataactg ctcgatacct tgctttaaac ttttctcttc taaattgact ggacgtagat
    20341 gaagaagcag cgcacgcatc tcagactggg aagcgttgat gatctctgct accattttca
    20401 actgcttgcg aaacatttct ggtgtctcgc ttttttctgc ttgctccgtc aatgccgaca
    20461 tcatcatcat tgctgcaaac aattgttgcg aaactgaatc atgcagctca cgggctaatc
    20521 gatgtctttc taattctaaa atttcttctt tggtttgtcc atctacatat tggggacggc
    20581 tcgttacaat ttgtaattca ctagatactt caatcatttt ttcttttatc ttagtgattt
    20641 ccttatcaat atctttgatg tataaatcgt ccgatgcact tgggatcgga agaagcaaca
    20701 atttggattc ataattgcca gaagaaagtg cacgcagctt ttcttcgatt ttcccgtatt
    20761 ttgtcttttg aataagtgat aataatagaa agacaattaa tcctacacct aaggaaatgg
    20821 ctaacaaatg gaagataagc ggaacatata ataaacgtgc acgcagtaat tctccccacc
    20881 aatgactttg attgctggca taaaaataag tgaaaagtga aaatagaata ataaggaaag
    20941 ccgcaatccc cgaataaaca gctagcatcg ctctggatat ttttcccatc atattcgtat
    21001 cacctcgaca tctccaatca aggtattagt aataatcttc aatctacgag ggttttcatc
    21061 ataatcactg ctgtagattt tgatttgttc atttttcaaa gaaaattgct cttcttcaaa
    21121 caagacattt cctactaatg tcgcatgctc taatcggatg gctacgccca aaggtactaa
    21181 gatccgtgtt ctgcctatcc cttttcttac aatcacaata ttatcatctt ttggcaaaag
    21241 cgtattgccc aaatctatga tagtatcacc agaaatgacg gcgatgttga tatcgtccca
    21301 ttcatagacg tcgtttccaa tacgttggtt accgaataat tgctgtcttt tccgctcatt
    21361 attatgtgtt tttaattgct ctgtttggat catcatgatc tgtttctttc gccaaaaagc
    21421 atttttggtt aaatctatcc ctgaaatctc tacacctttc agaccaataa ataaaacggc
    21481 aaatacagcc atcatccata aagcaggact gttgactaag ctaaaaaaaa tgaccaaact
    21541 tcctaatatc aattgaaaat tttgaaattt agtacgagga tgtttgcgca tagctagata
    21601 tatattgaaa ataccgaata tcactaaaag caaaagtcca gtattgttta cgatttgcca
    21661 aacagcaaat aacagcagta gtgcttcaac taccacaaaa aaacgccaag aactattcat
    21721 cgctctttct ccctcctgac acattctcat ttcatcatac ctattttttt aactgttggc
    21781 tataggactt tagatgtaag atcgtttgtt gaaatctaaa atacacaaag agaaaaagat
    21841 ctagagtgta tcatcagtaa gatgaactct ctagatcttt cagtcagact acgcttgttc
    21901 tactttgacg attttaacta acatatcgcc acctggagta gcaatagtta cttcatcatt
    21961 tttacgtttg ccaatcaatg cttgcgcaat aggagaatca ttggaaattt tgccagaaaa
    22021 cggatctgct tcagcgcttc cgacaatcgt gtactcttct tcttctccat ctggtagttc
    22081 gatgaatgta actgttttac caattgatac ctcatctgca tctacaccgt cgttatcgat
    22141 gatttgagca aaacgaatca tattttcaat tgttgtgatt cttccttcaa caaatgcttg
    22201 ttcatctttc gctgattcat attcagagtt ttcggaaaga tctccgaaac cgcgggcaat
    22261 tttgattcgt tcaatgattt ctccgcgttt gactgttttt agttcttcta attctttttc
    22321 taatttttct ttaccttcta gagtcattgg ataaactttc tctaccatgt gtaacgtctc
    22381 cttttttcga taaaataccg caaaaggtaa tcttttgagg aatatagtcc aaaaaagatt
    22441 accacgcttt tcttcaaatg taaatgtttt tctaaaaatg atcaatgtct agagcctgtt
    22501 tttctaagaa ttatttacat atttttccac taattccata tgttcttcat aagttttagc
    22561 gaaataaaca tttccagtgc tcgtatctgc tacgaaataa taatagtcat tttctgctgg
    22621 ttctaatact gccttgattg cctcttcgct tggattgtca aaaggtccag gtccatagcc
    22681 ggtattggta tacaaattat atggtgaatc tacagctgta tcttcatacg tcactaattc
    22741 tttgtgttca cctaatgcgt ataaaacaga gatatctgac tgaagtggca tatttgcttt
    22801 gattcggtta aagaagactt gtgcaatgtt tttacgatca ttttctttta cgccttcttt
    22861 ttcaactaga gaagctagag ttaaaacttc ttgtacagtc aaatttttct gcttgatagc
    22921 tgaataatag ttttgcatga ccgtattcgt cttgttcacc atttcaatca ctagatcctt
    22981 aagcgaagta ctcgtgtaat aatcatatgt ggctgggaat aagtaacctt ccaaacggta
    23041 ttttgtgttc tcagctttag atgcactttc caacagttct gggaattttt ggtgcaactc
    23101 gttaaagaaa gtctcatcat tcactaaatc taaaaattct ttcttgtctt taccagttac
    23161 cttcgctacc cgttcagcaa tctgatcgat atcgtaccct tctggaatgg caattttccc
    23221 atctgcaact tttgttggct cagaagtacc gccttcttgc aactgtttgc caatctcgtc
    23281 aagagtcata ttaggcgcta actgataata gccagcttga aagccagtta aatttttaaa
    23341 ttttgtataa taattgaaaa caatcccgct tttaataata ttgtccttct ccaaaatctc
    23401 accaatctgc ttgttagaag agccactcgg gatctcgact tggactaatt ggtcatctga
    23461 tttatctaaa ggcttcaacc cgctatctac ataacgatac acggtaaatc caagaaatcc
    23521 gccaataatc aataatgtaa gagcaatcac taaaatgatc ttcctcacaa tcttatcttc
    23581 ttttttacgc agatttctcc gcttgtcgat tatatctgct gtagctgcct tactggcttc
    23641 ttttttatct ttacttgggt gttgtttgtt tcctgacaaa acaactcctc cttactatca
    23701 agttcgtaac tttattcatt atacatgata tttgaattgg cgtgaatgat tttatttaaa
    23761 tattctatca aaaatgtaag tagtaaatcc attactataa gattaaaata aatgttatca
    23821 agatacaagc tattttagct ttattctttc tgtaaaaaag aaaggagact aaataaacta
    23881 ttatgaaaaa aggaaaacat gctaaaaaaa gaaaatattc atttttaatg atcgttgtcg
    23941 tgttgtttag ccttagtgcg ttctctacag gaactattct tggatggcaa ttttacaata
    24001 atgaacactc tcagatagtt gcccatgctc aatcagctca aaaaaagttg atactgacta
    24061 ccaatgaaca acagctcgtt gaaaaaatcg atcaactatt aagaaaaaat gattatattg
    24121 gctcaattta cgtaaagaaa aataatcgca tcatcatgga aaaaggctat ggctatgcga
    24181 ataaactcac gcaacaacca aatgatcctt ctctttatta tcagattggt tcggttcaaa
    24241 aagcattgac tactcttttg attttaaaac aagtcgagcg tgggcacctt tctttagata
    24301 ctaagctggc tcaattctat ccacaaattg ctggcagcca gcaaattact atccgtgact
    24361 tgctgtatat gcgctcaggc ttgcaccgaa ctgcttctcc aaccataccg atgactgatg
    24421 aagaagtcgt tcaatttgcg attcagcact taaaatttac agattatcag acctctcatt
    24481 atgattcatt gaactttacc atattgactg gaattttgat caaattaaca aatcaaccgt
    24541 atgaaaaatt attgaccgat gatatcatcg aacctttagg attacagcat acaaaatttt
    24601 atgaccaagt caaaaattca tccaatcatg cactatccta tcaaatgtct aaagaggatg
    24661 attactttaa accactgaca gaatctgaaa cagagatcca taacgaatta gggactggta
    24721 atatcagtat gtccgtctat gatttaaata cgctgtttac acaagtttta tctggaaaac
    24781 tagtttccaa agacttactc ttctcattat ggcgtgaaaa tgcgaatgga catccatata
    24841 gtggtggggt atatagcgga gataattata tcctgtcgca aggaaatatc gactcttttg
    24901 atacatctgc tatatttagc aaagattcac aggatgctat catcatggaa agcaatataa
    24961 aagctgacaa aactatcaaa ctgcctactg ctgatctaag aaaccaaatc tatgacctga
    25021 tggaaggaac tactaagttg gcaaatagct gatatgatga aaagatagca aatactactt
    25081 ctttgaatag catttgctta aaaaaagtac tcgactaaac gtaggaaaga gtgtgggaca
    25141 aatctaaaaa tcaatttttg ctacagactt taattccaaa taaacagaac agaaagaggt
    25201 gttcttcttt ctgttc
//
LOCUS       DAZKCH010000036        24618 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000036 DAZKCH010000000
VERSION     DAZKCH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.036"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(233..1081)
                     /locus_tag="ACG84X_001494"
     CDS             complement(233..1081)
                     /locus_tag="ACG84X_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9127369.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="ACG84X_001495"
     CDS             complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="ACG84X_001495"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFP9127370.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3582..3761)
                     /locus_tag="ACG84X_001496"
     CDS             complement(3582..3761)
                     /locus_tag="ACG84X_001496"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFP9127371.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3808..5631)
                     /locus_tag="ACG84X_001497"
     CDS             complement(3808..5631)
                     /locus_tag="ACG84X_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9127372.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5909..8188
                     /gene="helD"
                     /locus_tag="ACG84X_001498"
     CDS             5909..8188
                     /gene="helD"
                     /locus_tag="ACG84X_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFP9127373.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8281..8928)
                     /locus_tag="ACG84X_001499"
     CDS             complement(8281..8928)
                     /locus_tag="ACG84X_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127374.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9107..9826)
                     /locus_tag="ACG84X_001500"
     CDS             complement(9107..9826)
                     /locus_tag="ACG84X_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9127375.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9957..11108)
                     /locus_tag="ACG84X_001501"
     CDS             complement(9957..11108)
                     /locus_tag="ACG84X_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFP9127376.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11325..12065)
                     /locus_tag="ACG84X_001502"
     CDS             complement(11325..12065)
                     /locus_tag="ACG84X_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9127377.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="ACG84X_001503"
     CDS             complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="ACG84X_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFP9127378.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12449..13042)
                     /gene="yqeK"
                     /locus_tag="ACG84X_001504"
     CDS             complement(12449..13042)
                     /gene="yqeK"
                     /locus_tag="ACG84X_001504"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFP9127379.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13026..13676)
                     /locus_tag="ACG84X_001505"
     CDS             complement(13026..13676)
                     /locus_tag="ACG84X_001505"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFP9127380.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="ACG84X_001506"
     CDS             complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="ACG84X_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFP9127381.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="ACG84X_001507"
     CDS             complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="ACG84X_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFP9127382.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15119..15646)
                     /locus_tag="ACG84X_001508"
     CDS             complement(15119..15646)
                     /locus_tag="ACG84X_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFP9127383.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15826..16611)
                     /locus_tag="ACG84X_001509"
     CDS             complement(15826..16611)
                     /locus_tag="ACG84X_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFP9127384.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16604..17473)
                     /gene="accD"
                     /locus_tag="ACG84X_001510"
     CDS             complement(16604..17473)
                     /gene="accD"
                     /locus_tag="ACG84X_001510"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFP9127385.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17474..18853)
                     /locus_tag="ACG84X_001511"
     CDS             complement(17474..18853)
                     /locus_tag="ACG84X_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFP9127386.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="ACG84X_001512"
     CDS             complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="ACG84X_001512"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFP9127387.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19305..19781)
                     /gene="accB"
                     /locus_tag="ACG84X_001513"
     CDS             complement(19305..19781)
                     /gene="accB"
                     /locus_tag="ACG84X_001513"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFP9127388.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="ACG84X_001514"
     CDS             complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="ACG84X_001514"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFP9127389.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="ACG84X_001515"
     CDS             complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="ACG84X_001515"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFP9127390.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="ACG84X_001516"
     CDS             complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="ACG84X_001516"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFP9127391.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22811..23035)
                     /locus_tag="ACG84X_001517"
     CDS             complement(22811..23035)
                     /locus_tag="ACG84X_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFP9127392.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(23088..24050)
                     /locus_tag="ACG84X_001518"
     CDS             complement(23088..24050)
                     /locus_tag="ACG84X_001518"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFP9127393.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(24060..24500)
                     /locus_tag="ACG84X_001519"
     CDS             complement(24060..24500)
                     /locus_tag="ACG84X_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9127394.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         6756 a         5461 c         4274 g         8127 t
ORIGIN      
        1 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
       61 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
      121 tatttttgaa aattatgttc tcttaagtcg tgaaacactt tgatggatca tttatttgtg
      181 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
      241 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
      301 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
      361 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
      421 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
      481 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
      541 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
      601 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
      661 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
      721 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
      781 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
      841 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
      901 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
      961 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     1021 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     1081 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     1141 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     1201 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     1261 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     1321 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     1381 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     1441 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     1501 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     1561 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     1621 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     1681 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     1741 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     1801 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     1861 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     1921 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     1981 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     2041 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     2101 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     2161 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     2221 tagaccatca tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc
     2281 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     2341 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     2401 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     2461 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     2521 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     2581 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     2641 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     2701 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     2761 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     2821 tttgaaagaa cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct
     2881 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     2941 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     3001 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     3061 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     3121 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     3181 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     3241 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     3301 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     3361 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     3421 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     3481 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     3541 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     3601 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     3661 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     3721 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     3781 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     3841 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     3901 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     3961 aaaaatacaa ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct
     4021 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     4081 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     4141 aagtgctggt gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     4201 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     4261 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     4321 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     4381 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     4441 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     4501 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     4561 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     4621 tgcactagct gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc
     4681 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     4741 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     4801 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     4861 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     4921 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     4981 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     5041 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     5101 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     5161 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     5221 ctggtcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     5281 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     5341 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     5401 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     5461 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     5521 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     5581 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     5641 tcctctttta tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     5701 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     5761 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     5821 ttcgattcat cagttaaaaa gtaccttttt tcgaaaaact atgctatact tttaattcgt
     5881 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     5941 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     6001 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     6061 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     6121 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     6181 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     6241 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc
     6301 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac
     6361 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat
     6421 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     6481 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     6541 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     6601 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     6661 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     6721 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     6781 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     6841 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     6901 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     6961 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc
     7021 tttacatcat agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     7081 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     7141 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     7201 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     7261 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     7321 tctaacacga cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac
     7381 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     7441 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     7501 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     7561 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
     7621 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
     7681 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
     7741 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
     7801 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
     7861 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
     7921 acaacaagtc cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact
     7981 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
     8041 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
     8101 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
     8161 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
     8221 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
     8281 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
     8341 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
     8401 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
     8461 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
     8521 gtatgcacta tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag
     8581 aattttttca ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg
     8641 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
     8701 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
     8761 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
     8821 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
     8881 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
     8941 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
     9001 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
     9061 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
     9121 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
     9181 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
     9241 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
     9301 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
     9361 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
     9421 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
     9481 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
     9541 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
     9601 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
     9661 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
     9721 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
     9781 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
     9841 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
     9901 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
     9961 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    10021 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    10081 atagaaatct cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt
    10141 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    10201 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    10261 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    10321 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    10381 tacggccaat aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga
    10441 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    10501 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    10561 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    10621 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    10681 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    10741 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    10801 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    10861 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    10921 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt
    10981 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc
    11041 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    11101 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    11161 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    11221 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    11281 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    11341 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    11401 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    11461 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    11521 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    11581 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga
    11641 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    11701 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    11761 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    11821 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    11881 tctaaccctg tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg
    11941 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac
    12001 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    12061 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    12121 tccagattat agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga
    12181 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    12241 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    12301 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg
    12361 tcttctgccc gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct
    12421 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    12481 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    12541 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    12601 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    12661 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga
    12721 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    12781 aattcaataa ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    12841 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    12901 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    12961 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    13021 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    13081 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    13141 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    13201 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    13261 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    13321 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    13381 gtttcaatct gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt
    13441 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    13501 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    13561 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    13621 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    13681 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    13741 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    13801 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    13861 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    13921 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    13981 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    14041 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    14101 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    14161 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    14221 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    14281 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    14341 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    14401 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    14461 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    14521 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    14581 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    14641 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    14701 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    14761 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    14821 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    14881 accacattga cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg
    14941 tcatccgtca atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga
    15001 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    15061 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    15121 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    15181 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    15241 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    15301 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    15361 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    15421 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    15481 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    15541 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    15601 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    15661 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    15721 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    15781 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa
    15841 cctcttgtat cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct
    15901 ttcaatcaac gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt
    15961 gaacgtttca ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat
    16021 tttcatcaac tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa
    16081 tccttctgga gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa
    16141 acctagagca agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac
    16201 ctttaaatca gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc
    16261 tgctcctaca ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa
    16321 cttttccgct tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc
    16381 aaaatttctg cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac
    16441 cggtttgcca tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg
    16501 atcaccatgg cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca
    16561 tcgttcttta gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc
    16621 atcctttctg tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg
    16681 gaacaatctg atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg
    16741 gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt
    16801 ggggttctgc tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg
    16861 tcgggtccgt taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag
    16921 cagagatttt tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg
    16981 aagctgtgaa caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga
    17041 tcttttctcc gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa
    17101 taatgaaggg aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg
    17161 ttttatcttg cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg
    17221 ttacaagatc cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct
    17281 gccatgcacc gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt
    17341 ctttcgtata aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag
    17401 atggcgagtt agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct
    17461 taaacagagc catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt
    17521 cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat
    17581 ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct
    17641 gcatcttcat taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg
    17701 aatcataata tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca
    17761 tcccacctgc tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag
    17821 caggattttc tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt
    17881 gacacacatt caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc
    17941 ctgtgaccat ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat
    18001 aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg
    18061 ctttagctgc tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta
    18121 cagaaggaga ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc
    18181 ctaaatgaat gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag
    18241 gataaatgat tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct
    18301 gagctgaaga aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc
    18361 cgccaccacc tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca
    18421 atgcttcttc tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt
    18481 cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag
    18541 gaccaataaa tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata
    18601 aaaaaccaaa tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt
    18661 cctgaacatt cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg
    18721 ctaactgtgt atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc
    18781 ctagttcgcg gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata
    18841 ctttagaaaa catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt
    18901 ttaccgtcta ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc
    18961 tcaacttcaa ggtataaggt atctcccggt gtaactttct tacggaattt tgctttgtcc
    19021 aatccgccga aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct
    19081 cctgcttgag ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa
    19141 tgtccttgaa aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct
    19201 tcaaccattt cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct
    19261 tttatttctt gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc
    19321 ctaaagagtg gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc
    19381 actccgtcgg cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata
    19441 acttctcctt tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt
    19501 tgcagataaa cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat
    19561 tctttttctt tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc
    19621 tccgaaactg gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt
    19681 ttattcatat acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga
    19741 tcaaattgac tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt
    19801 tcatgcacag aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa
    19861 aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt
    19921 ctacattgat cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt
    19981 cgatcccgcc ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag
    20041 tatctctgaa attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg
    20101 ctggtgtact tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt
    20161 cttccatcgc aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca
    20221 tatggtaagc gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc
    20281 gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa
    20341 aaccattccg attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga
    20401 gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc
    20461 cagcaagaat gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat
    20521 tcgttccgct agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca
    20581 aagcaatatt tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc
    20641 gttttgcacc tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga
    20701 tcccagatcc gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc
    20761 tcatctccat tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt
    20821 tgctatcttt tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg
    20881 taatccctgt ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt
    20941 ttaagctatt caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag
    21001 taattaccac tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc
    21061 catcgacatt gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt
    21121 gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct
    21181 tgactttgtc tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat
    21241 tacatgtaat gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc
    21301 cagctttact agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag
    21361 agagattaat gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca
    21421 tattgaaggt tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc
    21481 gcatcacaag tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa
    21541 gcttttcttc tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg
    21601 aaactcctac gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct
    21661 ctccgcgacc attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt
    21721 tgccgattcc tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt
    21781 tcctccttat agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac
    21841 tggtattgtt ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc
    21901 gatgacttgt tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg
    21961 ttgcatgact tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt
    22021 tgtgttgctt atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc
    22081 cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg
    22141 gatcattctt ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc
    22201 ttcgccacca atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta
    22261 cttgctagct tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac
    22321 cattttcccg cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa
    22381 cgcaactgct tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa
    22441 actcagtcct aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc
    22501 gatgctgact gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc
    22561 tgtaaagcaa agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg
    22621 ctttacaacg gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc
    22681 actaaataag aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt
    22741 cttcctattc aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta
    22801 attttaatga ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga
    22861 ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga
    22921 ataaatccaa gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt
    22981 cagtttcttt tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa
    23041 tatattcctc cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg
    23101 agaatacttc cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt
    23161 cctaaggtga tctttccact agaaactgct tcatccaata agatagggat gcttgcagca
    23221 gatgtattcc catatttatc catattggtc aggaactttt cttgcggcat ctttactttt
    23281 cgggcaattt tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt
    23341 ttgtctttca tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata
    23401 tctctgccag tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt
    23461 ttattttgct ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt
    23521 tctttcagca attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca
    23581 aacaacacag cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca
    23641 atcaccagtc ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa
    23701 acaaatcctg agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc
    23761 ccttgtactt gtgctgctac agatggtgtc gtgtaatcgg gcgacattgt tgctactaaa
    23821 ataaaatcca aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa
    23881 atgcataaat cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt
    23941 gacgaaatcc attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc
    24001 ttttcaggaa ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct
    24061 cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt
    24121 tcctccgtag ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg
    24181 acccgaaata gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct
    24241 tcactgcgga tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag
    24301 gtcccaacag taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc
    24361 ccgattgcct cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc
    24421 agctcagact cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact
    24481 gtttttaaat ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt
    24541 gatgttcaaa ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac
    24601 tatatgagct ttttttaa
//
LOCUS       DAZKCH010000037        24311 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000037 DAZKCH010000000
VERSION     DAZKCH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.037"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(92..826)
                     /locus_tag="ACG84X_001520"
     CDS             complement(92..826)
                     /locus_tag="ACG84X_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFP9127395.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1153..1563
                     /locus_tag="ACG84X_001521"
     CDS             1153..1563
                     /locus_tag="ACG84X_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFP9127396.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1556..2257
                     /locus_tag="ACG84X_001522"
     CDS             1556..2257
                     /locus_tag="ACG84X_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFP9127397.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2257..3843
                     /locus_tag="ACG84X_001523"
     CDS             2257..3843
                     /locus_tag="ACG84X_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127398.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3862..4083
                     /locus_tag="ACG84X_001524"
     CDS             3862..4083
                     /locus_tag="ACG84X_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFP9127399.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4080..4841
                     /locus_tag="ACG84X_001525"
     CDS             4080..4841
                     /locus_tag="ACG84X_001525"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFP9127400.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5221..5730
                     /locus_tag="ACG84X_001526"
     CDS             5221..5730
                     /locus_tag="ACG84X_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFP9127401.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5805..6344)
                     /locus_tag="ACG84X_001527"
     CDS             complement(5805..6344)
                     /locus_tag="ACG84X_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFP9127402.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6484..7095)
                     /gene="rpsD"
                     /locus_tag="ACG84X_001528"
     CDS             complement(6484..7095)
                     /gene="rpsD"
                     /locus_tag="ACG84X_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFP9127403.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7357..8208
                     /locus_tag="ACG84X_001529"
     CDS             7357..8208
                     /locus_tag="ACG84X_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFP9127404.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8236..8871
                     /locus_tag="ACG84X_001530"
     CDS             8236..8871
                     /locus_tag="ACG84X_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFP9127405.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8891..9664
                     /locus_tag="ACG84X_001531"
     CDS             8891..9664
                     /locus_tag="ACG84X_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9127406.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10072..10869
                     /locus_tag="ACG84X_001532"
     CDS             10072..10869
                     /locus_tag="ACG84X_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFP9127407.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10847..11260
                     /locus_tag="ACG84X_001533"
     CDS             10847..11260
                     /locus_tag="ACG84X_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFP9127408.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11244..13889
                     /gene="mutS"
                     /locus_tag="ACG84X_001534"
     CDS             11244..13889
                     /gene="mutS"
                     /locus_tag="ACG84X_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFP9127409.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13907..16015
                     /gene="mutL"
                     /locus_tag="ACG84X_001535"
     CDS             13907..16015
                     /gene="mutL"
                     /locus_tag="ACG84X_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFP9127410.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16037..16597
                     /locus_tag="ACG84X_001536"
     CDS             16037..16597
                     /locus_tag="ACG84X_001536"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFP9127411.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16682..18670)
                     /gene="treP"
                     /locus_tag="ACG84X_001537"
     CDS             complement(16682..18670)
                     /gene="treP"
                     /locus_tag="ACG84X_001537"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFP9127412.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18893..19606
                     /gene="treR"
                     /locus_tag="ACG84X_001538"
     CDS             18893..19606
                     /gene="treR"
                     /locus_tag="ACG84X_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFP9127413.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19683..20129
                     /gene="msrB"
                     /locus_tag="ACG84X_001539"
     CDS             19683..20129
                     /gene="msrB"
                     /locus_tag="ACG84X_001539"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFP9127414.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20299..20901
                     /gene="ruvA"
                     /locus_tag="ACG84X_001540"
     CDS             20299..20901
                     /gene="ruvA"
                     /locus_tag="ACG84X_001540"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFP9127415.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20914..21915
                     /gene="ruvB"
                     /locus_tag="ACG84X_001541"
     CDS             20914..21915
                     /gene="ruvB"
                     /locus_tag="ACG84X_001541"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFP9127416.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21944..22522
                     /locus_tag="ACG84X_001542"
     CDS             21944..22522
                     /locus_tag="ACG84X_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9127417.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22574..23056
                     /locus_tag="ACG84X_001543"
     CDS             22574..23056
                     /locus_tag="ACG84X_001543"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFP9127418.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23173..23547
                     /locus_tag="ACG84X_001544"
     CDS             23173..23547
                     /locus_tag="ACG84X_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127419.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(23922..>24311)
                     /locus_tag="ACG84X_001545"
     CDS             complement(23922..>24311)
                     /locus_tag="ACG84X_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9127420.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT         7917 a         4359 c         5202 g         6833 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgaaata aaaaaacttg gtacgcaatc
       61 gctgtaccaa gtttttttat ttagcttttg attaagccat aaataataat ttatataaga
      121 atactgctac gacaccagca cagataggtg ctacaactgg tacccatgca tatccccatt
      181 gagaagaacc tttatgtttc aatggaagaa gtgcgtgtac aagacgtgga gcaaagtcgc
      241 gggctgggtt tagtccagga cctgtaggac caccaagtga agcaactaat gtccatacaa
      301 ggaaaccaag tgctaagtga gctgtaccaa gattatcttg gaagaatggt gcttttgtaa
      361 tacctagggc accaaagaat aaaacgaatg aaccaaagaa ttcattgacg aaaccattga
      421 atttagaacc aacgctgttg attgttgaga atgtacctaa cacatggttt acgtcttctg
      481 tttggtcgta gtaaggtttg taacaagcta ctacgatcaa ttgtccaatc gctgcaccaa
      541 tcaattgtgc aatgatataa ggaacaactt cagcccaagg gaatagacca ttagatgcta
      601 aagcaattgt aaatgctggg ttgatgtggt taccgctgat tccaccaaaa atcattgctg
      661 gcatcataac cccgaatcca tacccgacag caatcagcat ccagtcactg ccatatcctt
      721 ttgtaccttt taaatctacg tttgctacag caccgttacc tagaacgatt agtaatgctg
      781 taccaatcat ttccgccgca agacgggtca ttagtgagta atccataaat acctccaaaa
      841 gttataaaaa tgcaaaaaaa aaagaaacat caacacgaaa agcatcggtg cagtgtttcg
      901 tgtcggaagg atttctgcag tcttaacaaa tgtgaataaa aaaatgaatt ccattactta
      961 taagaaacca gaccaacagt aaaactccaa ctctttttaa aagttctcca caaatcacca
     1021 agcttaacta taaatatacc aaaaaaaaaa cgtttttttt ctcaaaaatt gtatcttaga
     1081 aacagcatgt tttgaaactt tcagaaaagg tttgttagta aaatgaaagc tatacgtaag
     1141 gagtgttgtt tgatgaaatt ttttcaagag tttttcatta ttattttctt ttctgtatta
     1201 ggagaaggca tacggatttt tgctcattta cctattcctg gaagtatctt aggtattctt
     1261 tttttatttt tagcatttga aatgcatctt gttgatcctg aaaaaatcgg agcaactggt
     1321 gattttttat tgaataatct agccatttta tttgttcctg ctggtgtagg tttattggaa
     1381 tattttgatg atattgcttc gatatggcct gttttactgg gagcagtcgt cgtgtgttcc
     1441 atcgtcacga tggttgcagc gggaaaaacg gcagaaggtg tagaagcttt gctgggctat
     1501 gtccgtaaga aaaaagcaga aagggtatct gtaaacgaaa tggaggagaa tcaaattgac
     1561 tgagtttttt gtgaatccat tatttggctt aagtttgact ttaggagtgt acgtattatc
     1621 tgacaaattt ttgcggaaat ataaactgcc tgttttgaat cctctcgtat tatcgattgt
     1681 tgttattatc ttatttttgc atttttctgg gatcagctat aaagactata atatcggggg
     1741 caattttttg actatgctga ttactcctgc gacagtggca cttgccatcc ctctttataa
     1801 aaacttccgt ttactgaaag agaattttta tcctgtaatg gctgcgattt tagcaggaat
     1861 agtcgcaaat tgcttggtta gtgtagggtt cggttacttc ttctctcttc ataaagagat
     1921 ggtgatctca ttactaccta aatctgtaac gacggctatt tctgtcgatt tatctcatac
     1981 gatgggcggg gtgaatgccg tgacacttgc tattgttgtc tctacaggta tttttggttc
     2041 gctgatcgcc actcatattt tccgcctatt caagatcgaa agtccagttg ctcgcggtgt
     2101 ggcgttagga agtacttctc atgctattgg tacagcaaaa gcaatcgaga ttggtgaaat
     2161 agaaggaatc atttccggac ttgcgatatg cgtcaacgga atattgaccg ttttattgct
     2221 accgttattc tttcagcctt ttgctggctt gttttgatgc gaaaaccact attttatgct
     2281 acaataacca aaacgttcga gcataaaaaa ggagggaaag acgtgtattt gtcttccgag
     2341 tatcttaaac aatttgataa agatctatat tataagattc tcctcctaga aagttttgag
     2401 gatcaagctt ggcataccgc tgcacaatta gcgcaagttg ttcagctgga tgcccgcagc
     2461 gtgtcgaaat acctgaacga gctgtctaaa aactatcagc agtttagcgg taagacacac
     2521 cctttgttta caaaaaatca ccgttctggt tataactttt atgatacgct cgattcaatt
     2581 gaacatgagc gttttttgat ctatctcgtg caaagtacgc tgaaattcca gttgctgcac
     2641 gacatttttt ttgaagaatt ccatacaatg taccaatttg cgcaaaagca ttacattagt
     2701 gaatctactg ctcatcgaaa aatcaatgaa tggaaacagc aactgcaaac ttacggaatt
     2761 cggctgcaac gaggtacata tatcgctcaa ggcgaagaag aaatcattcg actttacttg
     2821 catatgacat tctggcagtt gtttcgaggg aaaatctggc catttgaaac gatttctcaa
     2881 atggacgtaa agaatatggc agaacatatc atggcttttt ttaatgttcg tctgaacgag
     2941 atcaaaaaaa gacgattgga atatatgcta ggtgcctttt ttttaagaaa atcacagaag
     3001 cattatgttg tattgaatga gaaaaaaaga cggctgattt ctgacaatct gttgttccag
     3061 cgattttgcc aggtcatgga gccggtattt cctaattatt ttcaagtaga agacgagtta
     3121 ggcgcattat ttcttgtact gatgactcgt gaagaatatt atagtgatcc taagatacgg
     3181 aagaaaattt ttgattttca tcaacaagca aaaacaccgc cctttacagc cctttcagaa
     3241 gcaaaagccg ctctttctct ttatcaggaa gagcaggggc tgccagcaga aaatctaacc
     3301 ttcgaggcag aaaactattt attcagcagt cattttttcg cctatctttt tcctaatgcg
     3361 aaagaaacga ttgatggcaa tagtagtgat tttattaatc atttagttat tgaaaacaag
     3421 gaattgaaac aatggctcgt acattttttt gaaagtagac acaaacatcc caatcatctg
     3481 gcatttaaaa atcatgcgtt tttgatgggg cggtatctga ctgtgtttaa aacattagga
     3541 gcctttactc cacagcttcc aaagatcacg atccttttaa tgacagattt cccattattt
     3601 gaagagcaac tgttagagga gggattacgg acatttttcc gtaatgagta tcagctgatt
     3661 tttctgccaa cagattatcg ggggagagaa gttgatcttc tgatttcgac aagtaaagtc
     3721 caccgcaaac catgggcgga tcttgactat tttattgtga ctgaagaact aaaattaatt
     3781 gattacatcc aactatctca aaaatttgaa atgattcaaa aacaaaaact attaaaacaa
     3841 taacaaagaa ggagaaaaaa gatgacattt gaagaaattt taccagaatt gaaaaaaggt
     3901 gcaaagatta ttcgtaaagg atggagtgga tttgaacttt atgttgttct cgtatccgat
     3961 gatgaatttg atggctgtcc ggtgacgccg tacttattga tcaaaacaag tgacgaaggt
     4021 ttttccagct tcgctcctac agtttgtgat attttagcag atgattgggc gatcgtagaa
     4081 tgaaaaacca gtatccagat ctagctaaac aggttgtatt tatcacagga gctgcttctg
     4141 gaattggtgc tgcgcaagcc cgagcgtttc ttgaacaaga tgcttttgta tttggattag
     4201 atcaaaagtt cggtaaaatg gaagaaattt ctttgcgatt tcctgaaact tttgcctacg
     4261 cactaggtga tgttcgacaa atgaaagaac tccaacaagc ggtatcgaaa tgccaaaatc
     4321 attttggtga agttacgatt ttactgaata cagcggggat attggatgcc tacaaaccct
     4381 tgatggaaac tgacgaatcg ctgtgggatc tgatttatga gacgaatgtg aaaagcatgt
     4441 atcagctgac aaaaatcatc cttcctgata tgatccgcca aaaaagcgga acgatcatca
     4501 atatggcttc gattgctggc ttgattgctg gtggaggtgg gatcgcttat acaagcgcga
     4561 aacatgcgat tgtcggattt accaaacaac tcgctctgga ttacgcagga cagggtatcc
     4621 gagtaaaagg aattgctcca ggagccatcc aaacaccaat gaatgcggct gattttgaag
     4681 ggaaaggtga gatggcagag tgggtggcaa atgaaacacc agtcaagcga tgggcacagc
     4741 cggaagaagt agctgagctg acgttatttc ttgcctctcc tcaagcaagc tacatacaag
     4801 gaacgatcat cccaatcgac ggcggatggt tgttaaaata accttgtgtt tttttcaagc
     4861 ttctgtatga taaaactaaa gagagaaaca acggttgatg ataaaaaaag tcgatgactg
     4921 ttcccgacat tcgatgccga acagccagtt caaaaaattc tttttaataa tcgttaatat
     4981 tcgaaactaa gcggcttttc acgacctctt gatataaacg atattcaaaa gcttgcaact
     5041 gcggtaacaa gtccagccaa atgaaaaata taaggagcta tttttatttg accattctta
     5101 ttacttgttg cagggcagct ttttcactac cttctgcgac acttcagttg gaattttctt
     5161 cccatccttt ggtcgcggtc attaccaaga taaaattatc ttgcaaagga gaaatagaac
     5221 atggaaaaaa ataatacccg ttcagccaaa cgctggacaa cgacagatgt gactcggatg
     5281 gcgctagtca ctggtttata tgtggcagtg acgctggttt tgtctgtctt tagctttgga
     5341 gtgattcaga ttcgtctctc ggagatgttc aactatctgt ccttgtataa caaaagatac
     5401 atcgtcgcgg taacagcggg agtagctttg gctaatattg cttctcctct tggactgata
     5461 gatgttgcag taggaagcgt cagcacgctg cttgtattgc ttatcaacta taaaatcact
     5521 agtcgcatca aaaacatgaa aatcaaaatg gccgtgacag catgcgtatt tgctttttcc
     5581 atgtttacag tagctggtca gctaacgatt ttatatcaac tacctttttt cttgaattgg
     5641 tgggtgattg ctttaggaga attggcatca atgattgtcg gtgggataat tatttattgg
     5701 atcggtaaaa aagtggattt gtcaaaataa agatctgttt aatttaaaat agggcagcat
     5761 ggaagagact gaatgttgag tcttcttcca tgctgctttt ttgattaatt tgtatgaaga
     5821 aatcgattta gccgtttttt catcaagata ccgatataag ctgctccagt tgccttgatt
     5881 gcttccggca gtaaaaacgg cagtagtcca ctggcaaatg cagttgtaaa agtaagatca
     5941 ccacttattt tcagccagat cgttccgcag atcaatgcag caagagagcc cattagattg
     6001 gcaaagattg catataagta atgagcatcc gttctttcga tcatccaacc agttatccac
     6061 gtttgtaaga gaaatccaat caaatatccg ccagttggcc caaataaaac agctatacct
     6121 ccagtcatcc ctgaaaatac aggaagacca atcaagccaa gtaaaagata aactccaaca
     6181 gatatcaatc ctagttttct tccgagaaaa gttgctgtta atccaatagc aaatgtttgc
     6241 cctgtcaaag gaaccaaacc aaaaggaatg gtcatctgag aaaggacaga aataatcgcg
     6301 gcaaattccg cagcaagtat caattctttc aatgttcggt tcataacgcc ctcttttcgt
     6361 taacttaata tttttatttg gttaacgaaa ttgtaaaaca aagtgattac tttgtaaata
     6421 gaaaatataa aaaaagacca gctatccaat agatagcggt ctttttcaag aaagcttttg
     6481 aaattataag ctttggttgt agtattcaac gacaagagct tcgtcgattt ctggatatag
     6541 ttcgtcacgt tctggtaaac gagtcaatga accttccaat ttttcagcgt caaagcttac
     6601 gaatgctggg cgtccaacag ttgcttctac agcttctttt actgttacga tgttttgtga
     6661 tttttcacga actgagatca cttgacccac ttctacgtgg tatgaaggga tatcaacgcg
     6721 tttgccatca actaaaatgt gaccatggtt aactaattga cgtgcttgac gacgagtcgt
     6781 tgcaagtcct aaacggtaaa caacattgtc taaacgttgt tctagtaaga tcatgaagtt
     6841 aacaccatgt ttaccttctt tgattttgct agcttttacg aacaagttac ggaattgacg
     6901 ttcgttcatt ccgtacatgt gacgaagttt ttgtttttca gttaattgca tgccgtattc
     6961 tgattgtttg ccacggctat taggtccatg ttgacctggt gcgtaagggc gacgtgctaa
     7021 ttcttttcct gtgcctgaca atgagatgcc taagcgacga gaaattttcc atgatggtcc
     7081 tgtataacga gacattaaaa tttcctccaa tgaatataag tttttggagt aaaataatcc
     7141 gttgaaaaat tcataatcat atagtttgtt cttcaatctt cacctttgca gccgcggtta
     7201 cacaatcgaa cccgagacgg ggcaacaaac tagggatgag ttattatttt tctgctgcat
     7261 tattttacac aaattacagt atatgataga tcatccacga atgtcaagat aattagtaca
     7321 taaaaacgct ttacaaacct aggctgtctt tataaaatga gagggtatgt gcaaatggaa
     7381 aaaagcgaag gaagtttaag gagaaaatca atgaatccgg tatcaccatt atttgagaaa
     7441 atcgatgctt caattgaaaa gaaggcgaat ctttttgaaa acagcttttc acgttacgct
     7501 gttcgagcgg ttctcgcctg tttgtttttg actttaggaa cggctgtggc atttgcgatc
     7561 gcgatgaagg gggaagatat cgcgcatggt ctaggaaaga ttttatacgc atttatgttc
     7621 agctggggtc tggtcatgat tctatacatg aacgccgaat taggaacatc gaatatgctt
     7681 tatatgaccg tgggtgtttt tcggcagaga cttgctttaa gtaaggcagc caagattcta
     7741 tttgcctgta tttttttcaa tatgattggc ggtatattat gtggatttct aatttctatg
     7801 actacgccat ttcaagattt aacgttggac aactttatgt tagaatcaat agcagtaaaa
     7861 ctagcaaaac cttcagcaac gattttggtg gaagggatgt ttgcgaatat cgttgtcaat
     7921 accgctgtac tgatcagcat gcggatgaaa gaggatgtcg gaaaagtgat cacagtcgta
     7981 ttcatcattt tcatttttgc ttttttagga tatgaacacg tgatagcgaa ttttcctgcc
     8041 tttacgctta cttactttgc ttctcacgga cagatggatg gaatgacagt cagcaatgtg
     8101 ttacataatt tgttttttgc tttggcagga aattatattg gtggcggttt agtaatggga
     8161 ctgggatatg cttggctgaa tcagtcaaaa tcatcctatg tggactaaaa agtcgttcat
     8221 taaaggggaa gtgccatgga agttttagtt tttccaaaaa atgaggaaaa agcgttacaa
     8281 atggaaaagt acatgaaaaa tcttttttcc tttgctggag tacctaagcc ggaacgcgct
     8341 cttttacaac aaccgttact ggatgagagc aaaaatttat ctatttctga agttttagct
     8401 tttgttcatt attattatga acaaatcgaa agagagtatc agtatgtagc gatcgattta
     8461 gtccagaaaa acatcaaacg gcttacattt gaagacttag tcgtattgtt gccactagtt
     8521 cagaaaaaag aatggtggga cagcatcgac tcttggagaa aagtatacag cacatggtgt
     8581 aaagcctacc cagagcagcg tgaagaagtc tttcaattgt ttgaaaaaaa ggaagatttt
     8641 tggctacgtc gaatagcaat cacgttgcaa ttaggttata aacagcaaac agacacagga
     8701 ctattgatcc gagcaataga cgaagatcgt caaacaaagg aattctttat ccaaaaagca
     8761 attggttggg cattacgcga ttatagtaag accgatgccg attgggtaaa aagacagctg
     8821 acaacagatt tgagtaagtt agctgttcga gaggcaagta agtatttata agaaagcgag
     8881 acgacaagag atgagacgca aattatttgc ttttgatatt gatggaacgt tgttagattc
     8941 aaacaaacaa gctttagata gcacaagaga agcattggaa aaattacgca aagccggtca
     9001 tctggtcacg attgctacag ggcggagccg atttcatgcg caagagatca ttcgcgatct
     9061 tgattttacg aactacattt tatgtaatgg agcggccggt tttttagacc atgaacaagt
     9121 atataagaat ttactagatc gcgaccagtt ggatgcgttc gttcaagaag cgcatcatga
     9181 gcagatcgat acagcttttg tcagcttaga caatatcaag cgttcttctt ccaatgatgt
     9241 aacggtgatg gaagaagcga tgcattcttt cggtgctgtc ttgcctgaat tagatcagtt
     9301 ttttgcagag gaacaagaaa tataccaagc gttagcattt ttcgatcaaa catatgatgg
     9361 gaagttctct tcatatgata aaattcgatt tgtccgctgg catgagaaca gtgtagatgt
     9421 cgtacctaaa aatggttcta aagcagcgac aattctgcac ttagcagaac aagtaggcat
     9481 ccctcatgaa gacatcatca gctttggcga tggacaaaac gaccgtgaaa tgttgcgcat
     9541 gtcaggaatt gggatagcta tggggaatgc tgtgccagaa gtacaagcag aagctaagat
     9601 ggtcactgat acaaacgatc aggatggaat ttggaaggca ttgaaagagt taagcgtgat
     9661 ttaaaagagg ttgtgaaaaa gctgttctgc atcaagtaat aagcccagcc aaacaaaaat
     9721 agctcctcct atttttcgtt tttctgggct tattaccgca gatgcaagct ttcgaacacc
     9781 gtttaaggaa gaggtcgtga cagaagtggt cagtttcaag aaataagaag ggatttacga
     9841 aaattgcttc tcaaattttt gtaaaattac ggcttatttc tgaagaagta gatgaaacaa
     9901 cgtttattcg ggaaatggga ctgtgacaag atgtttgtca tagtcccatt tttttatttt
     9961 atttttcaaa actaagaaat accaggaaag agttcctttt gtttgacctt ttctttctta
    10021 ttgaaaacaa ctataatata gagtgatgtt aaaagagaag aggaatttag tgtgcgggta
    10081 ttgtttattg gtgatgtagt aggttcaatg ggacgagaga tgattactga atatcttcct
    10141 agattgaaga agaagtaccg tccgcaagta acgattgtaa atggtgagaa tgccgcttct
    10201 ggacgtggaa tcacagaaaa aatctataaa aaatttttgc aagacggcgt agatgtcgtg
    10261 acgatgggga atcatacgtg ggacaaccgc ggaatctttg agtttgtaaa tgaagctaaa
    10321 aagatggttc gtccggcaaa ttttccggaa gggacgcctg gacaagggat ggtctttgtc
    10381 aaagtgaacc aagtcgaact ggcagtgatc aacatgcagg ctcgttcttt tatggtggac
    10441 ttggatgatc cttttcgtaa aatgaatgag ctggtagaag aagccagaaa acgtacgccg
    10501 atcatttttg tagattttca tggagaaaca acaagtgaaa aacaagcaat gggctggttt
    10561 ttagatggga aagtttcagc agtggtcggt acacatacac acgttcagac aaatgatgcg
    10621 cgaattttgc caagaggaac agcgtatctg acagacgttg ggatgacagg tccctatgat
    10681 ggtattttgg gtatgcgcag agaacctgta atcgaaaagt ttctgactgc attaccaaaa
    10741 cgttttgaag ttgtggaaca aggccgatcg attttaagcg gctgtatctt ggaattggat
    10801 gatacgacag gtcatgcaaa agaaatccag ctgattcaga tcaacgatga tcgaccgttc
    10861 atggagtaga aagagaggca gttttttgca gcaggagccg gaaattcaaa aagaagtaag
    10921 gaaactgaca aaacttttaa gagagaatga aacgatcatt cgctacaaag aacttgaaga
    10981 aaagatccag caaaaccagt atttagctga gttgagagaa aaaatcaaac aagcgcaaaa
    11041 agatgctgtt cattttgccc actatgacaa accagcagca gaaaaagaag caatcaaaca
    11101 agcggatcaa ttcatgcaag aatttgatca gcatccgctt gttgtagctt atagaaaaca
    11161 gctgttggaa gcagatgatc tgcttcatca tttaacaact atgatacaag aagaaatcaa
    11221 tggacaaata gaggaggaaa aacatgcctc aaaaaactaa aaatactcct atgatggaac
    11281 aatatctaag catcaaggcc caataccaag atgctttttt gttctatcgt ttaggagact
    11341 tttatgaact attttacgaa gatgcgatca aagcgtcaca gcttttggaa ttaacgttga
    11401 cgagcagaaa tcgaaatgca gaagaaccta ttcctatgtg cggtgtacct caccatgcag
    11461 cacaaggata tatcgatgcc ttgattgaaa aaggctataa agtagcgatt tgcgagcagg
    11521 tagaagatcc aaagacgact aaagggatgg tcaagcgcga agtgatccag ctagtcactc
    11581 ctggtacagt catggacagc aaaggattgt cggcaaaaga caacaatttt ttaacagctg
    11641 tagttagtca aggaaatgaa tttggctttg cttatgccga tttaagtacg ggagaattga
    11701 agacggctcg gttgcatgat gaagaagctg ttttaaatga agcctctgca ttgcagacaa
    11761 aagaactcgt attaggcagt gagatcactg atacccttcg tgaacagcta agcgggcgtt
    11821 tagggctagt cttttctcaa caaaatgaga tggaagaaaa cgcggaattt agctttttga
    11881 caagcgaact agtcgatccg ctggaaaaag aagcaaccgg caaactattg acttatttat
    11941 cggtgacaca aaagcggagt ttagctcata tccaaaaagc agtagaatac caaccagatc
    12001 attttttgaa aatggattat tattcaaaat tcaacctaga attaagccaa tctattcgga
    12061 ctgggaaaaa gcacggcact cttctatggt tgttagatga aacaaaaaca gcaatgggtg
    12121 gccgtttact aaaacaatgg ctagaccgtc cgcttatcca ggcaaaacaa attaaagcaa
    12181 gacaagaaat ggtcgcttct ttgctagaca gctattttga acgtatcgat ttgcagtcag
    12241 cattaacgaa agtctatgat ctggaacgcc tagcaggtcg agtagctttc ggtaatgtca
    12301 atgggcgaga cttgatccag ctgaaaactt ctttagaaca agtgccaatg atcagagggt
    12361 tgattgaagg aatcgatcaa ggtcaatggc aaagtctgct ttcagaaatg cagccgatgg
    12421 accatctcgt ccaattgatc gaccaagcta tccaagatga tccgccgtta caaataacgg
    12481 aaggaaacat catcaaagat ggattcaatg agcagctcga tatgtaccgt tctgctatga
    12541 gaaacggaaa gaaatggttg gcagaacttg aagcaaaaga gcgtcaagaa acaggaatca
    12601 agaacttaaa aatcggattt aaccgcgttt tcggttatta tatagaaatt acaaaagcaa
    12661 atcttggaaa tgcagaactg gagaagtatg aacgaaaaca aactttagca aatgcagagc
    12721 gtttcatcac accagaacta aaagaattgg agacacaaat cctcgaagca gaagaaaaat
    12781 ctgttgattt agaatatcag ttgtttttag ctgtgagaga agaagtcaaa aaggctatcc
    12841 agccgctaca agtacttgca aaagcaatca gtgcagtaga tgtgctacaa agttttgcaa
    12901 cgatcagcga acgctatcag tatgttcggc cagaacttgt cagtgacaag catcagcttc
    12961 tgatcaaaga cggacgacat cctgtagtag aaaaagtatt aggacatcag gaatatatcc
    13021 ctaacagcgt agaaatggca gaagacgaaa tgatcttgct gattacagga ccgaatatgt
    13081 ctggtaaaag tacgtatatg cgacagttgg cattaactgt tctgatggcg caaatgggct
    13141 gtttcgttcc ggcaaaacaa gcagttttac ctatttttga tcggattttt acccgaattg
    13201 gtgcaagtga cgacttaatt gctggacaaa gtacttttat ggtagagatg atggaagcca
    13261 atcaagccct gcgttatgct acgccaaaca gtttgatttt gtttgacgaa ctagggcgag
    13321 gaacagcaac ctatgacgga atggcgttgg cccaagcaat catcgaatat atccatcgtc
    13381 atgtacaagc aaaaacactc ttttctactc attatcatga actgacggta cttgagaaag
    13441 aacttccgca gcttaaaaat gtccatgttg gagccgttga aaaagacgga gaagttgtct
    13501 tcttgcataa aatgatggat ggacctgcgg ataaaagcta cggcatacat gtggcaaaga
    13561 tcgcaggatt gccttccaat ctactagaac gagcagcaga tatcctgcat acgctagaaa
    13621 atggcgataa cggacaccat actgttccag ctgaagtaga agagaaaact aaaacagcca
    13681 aacaggagca aataaaacca cctgcagaaa aagtaaatca agaccatata caagaccgtg
    13741 taaaagaaga aaaccaacag ctttctttat tcagtgaatt atccgaaaat gaaacagaag
    13801 tcattgaatc actgaagcaa ataaatttac tagaaatgac gccaatggat gcactaaaca
    13861 cattatatga attacaaaaa caactgtagg aagaaggcgg atatcgatgg ccaaaatcca
    13921 agaattatct gaacgtttag ctaatcagat cgctgcggga gaagtagtgg agcgaccagc
    13981 ttccgttgtg aaagaattag tggaaaatgc aattgacgcc ggcagtactc agattgatat
    14041 cttagttgaa gaagcgggac tgcggacgat ccaagtgatt gataacggag aaggcatttt
    14101 ggcagacgac gtagagaatg ccttcaagcg gcatgcgaca agtaagatcc ataatcgcga
    14161 cgatcttttt cgcatacgaa cgctgggctt tcgaggggaa gctttgccaa gtattgcctc
    14221 tgtttctgaa atgactctgg aaacggcgaa tcaggaagaa aaacaaggca cctatctgtc
    14281 gctgaaaggc ggagaagtta ttgagcatcg accagcacca ctgcgtcaag gaacgaagat
    14341 taccgtcagc aatctgtttt tcaatacgcc agcccgcttg aaatacgtga aaacactgca
    14401 cacagaatta gcgaacatcg gggacatcgt caatcgactg gcattgagtc atccatcgat
    14461 tgcttttcgt ttagtacatg atggaaacaa aatgctggca actgctggaa atggcgatct
    14521 gaaacaaaca attgcgggaa tctacggatt atctaccgca aaaaaaatgc tgaaaatcga
    14581 aggaaaagat ctagattttg agttatttgg ctatgtttca ttgcctgagg tgactcgtgc
    14641 cagtaggaat tacttatcga cgatcatcaa tggacgtttt atcaagaact tttccttgaa
    14701 taaagcaatc gttgcaggtt atgggtcaaa attaatggtc ggtcgtttcc ctattgctgt
    14761 attggaaatc aaaatggacc cgcttttagt agatgtaaat gttcatccga cgaagcagga
    14821 agtccggctg tcgaaggaaa aagaactaac agagctaatt agtaacgcca ttcaaaaagc
    14881 attgtctcaa gaaaatctga ttccaagtgc agcggataat ctacggttta agaaaaaagt
    14941 acctgatcag cctaaaacag aacaaatcga aatcgatttg tcctacgctt ttgaagaaga
    15001 aaaacctaaa aagccaagta gtttgaattt tgatcgagag acaggtacct ttttcgtaga
    15061 agaactaaag aacacatttg ttgacagaat tgttgataag tctgtggaaa atgttgaaaa
    15121 ctattctggt ttttctgaag aaaacaccac ttatccagaa aaaacagcga aaacggtgga
    15181 taagtttggt gaaaatgttg ataactttgt agaaaaaaca gtggaaaaat ctgaaaagaa
    15241 agaatttccc attgtggata acatggagaa aacaaatgaa gaacaagcag ataaatccgt
    15301 agaagaggat gaaaagattt acgaggaaga attgacactc catcctgaat ttgatttcac
    15361 tcaaggaaac gacaaaacat tagaacaagc catcaagaaa ttagaaacgg aaaaaccagt
    15421 acaacgtttt cctcagttgg aatattttgg acagatgcac ggaacgtatc tttttgccca
    15481 aagtagcgat gggttgtaca tcattgatca gcatgctgcc caagagcgca ttaagtatga
    15541 atatttccgg gaaaaaattg gggaagtatc tgatgatctg caagaattgc ttgttccatt
    15601 tgtgttagac tatccaaaca gtgatgcttt gaaattaaaa gagcaaaaac acttgctaga
    15661 agatgcaggg atttatttag aagaatttgg tcaaaacagc tttattgtac gggcccatcc
    15721 tacttggtat cccaatggag aagaagaatc gattattcgg gagatgatcg atatgctgct
    15781 gacaactgga agtgtgagtg taaaaaaatt ccgtgaagca acagcaatca tgatgagttg
    15841 caaacgatcg attaaagcca accattattt gaatgaagca caagcacgtg tgctgctgaa
    15901 ggatctggca cgatgcgaaa atcctttcaa ttgtccccat ggccgtccag tattgattca
    15961 ctttaccaat tcggatatgg aaaggatgtt caaacgaatc caagacccgc attaagtcaa
    16021 agagaagagg gaaaacatga agattgtatt agcatcccaa tcaccaagaa gaaaagagtt
    16081 attggctcat atcgtttcag aattcgagat tgaacctgct gatatcgatg aaacgccatt
    16141 tccagacgaa cagcccgtcg attatgttcg tagaatggct gaagaaaaag cacgaactgt
    16201 ctgggaacaa gatgaaaaag aagaccattt agtgattgcc agtgacacga ctgttgttct
    16261 caatcaagag atcatgggta aaccagaaga tctggctgag gctgaattca tgctgaaaaa
    16321 actaagcggg gaaacacata ctgtatatac agctgttgtt ttaaaaacaa aggaacgaga
    16381 agaacggata ctagcagaag cacatgtcac tttttatcct ttgacagacg aagagatcaa
    16441 acgctacttg gagacggggg attatgcgga taaggcaggg gcatacggca tccaaaatgc
    16501 tgcgagtgta ttcgtcaaag aaatttctgg agattattac agtatcgtag gatttccgat
    16561 tggtgctgtc aatcaggcac tgaaaacatt catttaaaca aaaaagcgga ctatctgatt
    16621 ttcgattgaa aatccatgat agcccgtttt ttttattgaa aagattactt atctactctg
    16681 actaagattt tacttcagct ttaccgactg cttcgcccgg gcgaacaagt cctgattggt
    16741 caagagaaag tcctgcaact ttttcattat tggtcaaagc aacaataatg tcagttttct
    16801 tgccagcttg ttctatttct ggcaaatcca tttcagcaat cagggtctct ggtgtgacaa
    16861 ggtatccttc tttcacgaat acattgaaag gaacaccctt tagttcaaca gtatctaatc
    16921 ccatgtgaac aagtacttcc agcccctcat tagaaagaat accaatggca tgttttgttt
    16981 caaagacact cgtcacttta ccgtttactg gtgcatagac tttgccgttt gacggttcga
    17041 cagcataacc gtcacccatc attttttgtg agaaaactgg gtcatttact tcagttattt
    17101 ccttgatggt ccctgcagcg actgcgaata atgtttcttt tgttgcaact gccgtaccag
    17161 ttgctgaaac aggttcgaaa gactgtggcg ttgctgttgc gccatttgct gtttgaagtt
    17221 gtacatcagc agcattttca ggaacagcag gatcaatctt attcaaaatt ccctgacgtc
    17281 taaagatgat cgtcaagcca aatggaatga tgacagcaat gatcattgcg atgatgaaag
    17341 gtacccatgt ttctgcttgg atagctagta ttcctggcaa accgcctact ccgatcgcgt
    17401 tagctcgaac acccatcaag ttagcaaaca tgccagctaa tccagagccg accattgcag
    17461 cgacgaaagg atagacgtat ttcaaattga ttccgaacat agcaggttca gttacgccta
    17521 agtaacaaga aatcattgct ggaatcgaga tttgttcttc ttttttattc ccacgatgta
    17581 agaagatgat ggctaagact gcagagcctt gggcgatatt tgataaagca atcatcggcc
    17641 ataaattcgt tgatccgaaa tctgcaatca gctgcatatc gatggcattg gtcatatggt
    17701 ggagaccagt aatcactaaa ggagcataca ggaatccgaa tacggcacta aacaaccagc
    17761 tgatagaaga cgtcaatcca gtatttacga tatttgagat ccagcttccg actgtccagc
    17821 cgataggacc taaaataacg tgtgcagcta aaacagttgg taacaatgaa aacaatggaa
    17881 caaaaatcat cgagatcgac tgagggatat atttgcggaa gaagatttct agatacgcta
    17941 acataaaccc tgccagcatg gctggaataa cttgcgcttg ataaccaatc atctggactt
    18001 gagcaaaacc aaaatcccaa aatggaatat ctgctgcggc tgtggaagct acactataag
    18061 catttaataa ttgcggagaa actaacgtaa ttcctaaaac gattcctaat atttgtgtag
    18121 tacccatctt ttttgcaata ctccaagtga tacctactgg aagaaaatgg aaaattgctt
    18181 caccgggtaa ccacaaaaag gcattgacac cattccaaaa cttcgagtgt tcaacgattg
    18241 ttccaccaag actttcaaac tggatacctt caagtacatt tctgaatcca aggatcaatc
    18301 caccgacaat gattgcagga atcagtggtg taaagatttc tgctaaaacg gcaatagcac
    18361 gttgaacggg atgaaggttt tgttttgcag ctgcttttcc ttgttctttg gaaacccctt
    18421 caactccaga tactgcaacg aagtcgttat aaaaagtaga aacatcgttt cctatgatga
    18481 cttggaactg tcctgcattc gtgaacatcc cttttacgct aggtatatct tcgatcgctt
    18541 tttcgtccgc ttttcctgga tcattcagga caaaacgcat acgagtcgca caatgactaa
    18601 ctgcagcaat attttctttt ccgccgatat catgtaacag cttctcggca tctgcttgat
    18661 attttgccat atcaataaac ccctttctct taacttgtct atgcaagtta tttcttcatt
    18721 tactatactt tttttcggag agaattgcaa gcgttttatt aaaaagtacg agagaaaatg
    18781 atatcgtttt aaaaagctta aaataagctt ttcttaaaaa taggaacatt gaaatacaaa
    18841 aagagctgta gtatagtgaa gaaatgatgg aagaacgagt gagggaaaaa acatgaataa
    18901 gttcaatgaa atttttttag atttggaaca gaaaatttta gcgaaagaat atcctccgca
    18961 ttcgctttta cccagtgaga accaattgat caaaatttat ggtgtttcac gagaaacaat
    19021 tagaaaagcg ctgaatcttt tgactacgga aggttatatt caaaaaaaac aaggaaaagg
    19081 ttcgatcgta ctggatcgga atcgcttcga ctttcctatt tctggattga ctagctataa
    19141 agagctacag gagacccaac gtattccaag tgaaacgatc atccatacgt tagaagaaac
    19201 agaagtgaca aaagcattga acgagatcac tggctgggag atcggtgcgc ctgtttggca
    19261 tttgatacgc gaaagaaaaa tcaatggcga agtagttata ttagacaccg attatctatt
    19321 aaaggaaatc gttcctattt taactccagc acaagcacaa ggatcgatct atgaatattt
    19381 tgaaaatgag ctttctttga cgattgctta cgcgcaaaag gagatcacag tagaagaagt
    19441 aacggaaatc atgaaaacag cgatggatct tcacgatgac acttatgcag tagtagtcag
    19501 aagcctcgtt catctggaag atacccgctg tttcgagtat tctgagtcgg ttcaccgatt
    19561 agataaattc cgtttcgttg agtttgcccg acgccgaaaa gtgtaaatag ttcaaaagaa
    19621 agcaaattgt tggcatctgt ccactttggc gctatgatag gatcacaaag ggggcatttt
    19681 taatggataa accaataaga ccagaaaaag aagaactgaa agaaaagtta tcacccatgg
    19741 cttatgcagt cacacaagaa aatgcaacag aacgaccatt tagcgggaaa tatgatgatt
    19801 tttacgaaaa ggggatctat gtagatatcg tcagcggtga accgttattc agctctgcag
    19861 aaaaatatga tgcaggttgt ggctggccat cattcagcaa accaataacg aaaagacaag
    19921 tgcgcgaaaa agccgatttt tctcatggca tgcatcgaat agaagttcga agcaaagaag
    19981 cagattctca tctcggacat gtgtttaccg atggaccagt agatcaaggt ggtctacgtt
    20041 actgcatcaa ttctgcctca ctgaaattca ttccatatga aaagatggat gaattaggtt
    20101 atggggaatt caaatcactt gtagaataat ggaaatacac aaagagcggt acaatacggg
    20161 gatttactcg atcgtccgct ctttttttat tcaagcgatt gctatttgaa agaaacgctc
    20221 cctagactcc ttttttcaca aggtgaaatg tgctacaata aagggaacgt atgtgtgcaa
    20281 aagaaagagg actagaatat gtatgaatat ctgacaggtg tggttacctt tatcaacccc
    20341 tattacatag tagtagaaac caatggtatc ggctaccaga tcgcactagg aaatccttac
    20401 cgctacagta gcaaactaaa tcaaaaaata aaaatttatg tccatcaggt aatacgtgaa
    20461 gatgcgcatc ttctgtatgg atttgattcg ctagaagaaa agcaactgtt tttgcgatta
    20521 gtaagtgttt caggaatcgg tccgaaaagt gcccttgcaa tcatggcaag cgaagaccac
    20581 tccggtttga ttcaagcagt agaatccagt gatgtcactt atttgacgaa atttccagga
    20641 gtagggaaaa agacagcaca acaaatgatc ttggatctaa aaggaaaatt cggtgagctg
    20701 agtatcgata caccttttag tctatttgat gaagcaaaca caaaagacgc tacagctcta
    20761 tctgaagcaa tggaagctct ctcggctctt ggttacagtg atcgagaaat caaacgtgta
    20821 gaaaaacaat taaaagaagt agataatcag acaacggatg agtatctacg ccaagcactc
    20881 aagctaatga tgaaaaaata aggaggagac caaatgacag atgaatactt gttatcacca
    20941 gaatctggcg aaaatgaact gagtttggaa aaatctcttc gaccacagct gctttctcaa
    21001 tatatcggac agagaaaagt caaacaagaa cttcagattt acatcgaagc tgccagaaat
    21061 cgggaagaac ctttagatca tgttctgttg tacgggcctc ctggattagg aaaaacgacg
    21121 atggccatgg tcattgctaa tgagatgacc gtaaatattc gtacgacgag tggccctgct
    21181 atcgaacgtc cgggtgactt agtagcaatc ttgaatgaac tggaagcagg ggatgtcctg
    21241 tttatcgatg agatccatcg attacctaga gtggtagaag agatgcttta ttcagctatg
    21301 gaagatttct atgtagatat catggtagga caagggccaa ccgcacatcc ggttcatttc
    21361 cctcttcctc cctttacttt gattggcgcg acgacacggg caggtatgct ttctgcacct
    21421 ttacgagatc gatttggcat catttctcat atggaatatt atgacgaaca ggatctgcag
    21481 gagatcgttt tacgttcttc ggatattttt caaacagaga tcattgaaga aggggcattg
    21541 gaaattgctc gccgatcacg aggaacgcct agaatcgcta atcgcttgct caaacgggtt
    21601 cgtgattttg cgcaagtcca aggagacggg aaaatcgatc gtcctatagc ggatcaggca
    21661 cttactttgc tacaggtcga tcaggctgga ttggattatg ttgaccagaa attgttgcga
    21721 acaatgatcg agttatatgg cggcggacca gtagggttaa gtacgctttc agtaaacata
    21781 ggagaagagc gtgagacggt agaagatatg tatgaaccgt atctgatcca aaaaggattt
    21841 ttaaagcgta cacctagagg gcgaattgct actgcttatg cctatgaaca ttttggttac
    21901 gactatcata tatgattttt gcttttagat tggaggaaaa tgaatgagtg atacaacacg
    21961 tacgaaacaa ttgatcaaaa acgtattgat tgatttgtgc caaacgcaat cttttcgaaa
    22021 aatcagcgtc caaaaaatcg caaacgaagc aaaaatcaat cgacaaacat tttattatca
    22081 ttttacagat aaatacgatt tgcttcgttg ggtctattgt gaggatgcat tgcattattt
    22141 agatccacaa tgtctttcac ttgataattg ggaagagcaa gcattgaaaa tgctgaaagc
    22201 aattgctgag aagaaagaat tttatgcaaa tactgtgctt tctgacccag aaattttaca
    22261 aaaagagttt tctcaactga tccaaaaatc atttatcaag atttttgaac aaatggatga
    22321 agaaagacaa ctttctgcaa gagacaaact attttatgct cgtttttttt cttacggttg
    22381 cagtggtgta ttagtcaatt ggatcacgaa tgaatatgaa gaaacaccga tggaaatcgc
    22441 tatgcagctt ttccgtttag ccaaggatac ggaattatat tcttatcgtc tttatgcaaa
    22501 agaagagttg gaagaacagt aatagaaaaa ttttttgttg gaaaagcaat aatcgctaaa
    22561 aggagatggg gaaatgacaa aaattttatt tgtttgtttg ggaaatattt gccgttcacc
    22621 gatggcagaa ggcttgctga gaaaacgaat agcattagaa ggaagggaag cagaattttt
    22681 tgtggattct gctgctacaa gcacgtatga agttggaaag acaccgcacc ctggaacgaa
    22741 aaaaatatta aaccaagaaa aagtagatat gacgaatatg gttgctcggc aaatcacacc
    22801 ccacgatttt gaaacttttg attggatcat tggcatggat caagaaaatg tagaagaact
    22861 gaaacgaaga gcaccacgct cagcgcaggg gaaaatccat ttgtttttaa gtagcattcc
    22921 tggaaaagaa aaagaaaatg ttcccgaccc atactatacc aataactttg atgagacata
    22981 tcacttgatc acagaaggcc tgaatcattg gtggaatatt tggattgatg aaaataaaat
    23041 aacaaacaat ttgtaaagtt aacgctttct ttttaaggcg atgttagagc atttccttgt
    23101 ttttttgtaa aatgttaggt aaaataaaat taattaagta acactttctt agctaaagga
    23161 ggagtgcatt cgatgaacga agagacagta tcgccaatga agaagcttac gaagttagtt
    23221 actcatactt cgtatcaact ttttgattct tttgtaaatg acactgaaga acatgctaag
    23281 aatgtacgat tgcaaggaaa gtttattctt gagctgcaaa aagctgctac tgaacatagt
    23341 ctagttatct tacaagtaag agcaaatcgt ttgagtagca agtatgaaac gatctcaggc
    23401 tgggtggcga caaaaacggt cgaaaaagac cgagtgatga tccgcctaca aaacgaagag
    23461 cagcagatcc ggatggttcc tgtagaacaa attgaaaaaa taacaatcct ttcaccagca
    23521 ggggaacagg aacggttatc aaaataattt ataccagata gaaaagcacg tatgagcttg
    23581 taccatcaat cattactaat caaaaataac cgaatgcttt aagctgatat cagtaaaacg
    23641 gaacgtttta ggatgagtat cacagcatga cagcattggg ttgattagtt gaatcgattg
    23701 gatggtacaa gtttttttga taaaaaaagg tcctgctagc cggggagcta gcaggataag
    23761 gagttaaaaa tgaaaaagtg ttgttagggt tgtttgttgg tatgcttata taatagtcac
    23821 tagttgtgaa tattttgtga cgaaagtttt cgaaagttgt taagtttttg ggagcgtcaa
    23881 taattttgtg taaataaatt gtcctcctgc aaaataatta gttactcagt aaacattgaa
    23941 actaatgtat cggttacctg ttgaaaacct ttatggcttc tgtttagaaa tttttgattg
    24001 tatgtatcaa aaatgctgac tagaaagcgt tctagtgatt cttcattttg aaactgctct
    24061 tttctacggc tgtatctttt aatttgctta ttgaaagact cgattagatt ggttgagtaa
    24121 atggttctac gaatgctagg tggaaaatca taaaaagtta ataagtcttg gttttctatg
    24181 agtgactgcg tcactttagg atagtttttc ttccatttct caatcatgcc ggataagaag
    24241 gtattcgctt cttcttttga gttagcttga taaacagcct taaagtcatc acagatttct
    24301 tttcggtctt t
//
LOCUS       DAZKCH010000038        23803 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000038 DAZKCH010000000
VERSION     DAZKCH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.038"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            365..1804
                     /locus_tag="ACG84X_001546"
     CDS             365..1804
                     /locus_tag="ACG84X_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9127421.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            2099..2317
                     /locus_tag="ACG84X_001547"
                     /pseudo
     CDS             2099..2317
                     /locus_tag="ACG84X_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            2566..2781
                     /locus_tag="ACG84X_001548"
     CDS             2566..2781
                     /locus_tag="ACG84X_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127422.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(2998..3254)
                     /locus_tag="ACG84X_001549"
                     /pseudo
     CDS             complement(2998..3254)
                     /locus_tag="ACG84X_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3441..4352)
                     /locus_tag="ACG84X_001550"
     CDS             complement(3441..4352)
                     /locus_tag="ACG84X_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFP9127423.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(4371..5375)
                     /locus_tag="ACG84X_001551"
     CDS             complement(4371..5375)
                     /locus_tag="ACG84X_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFP9127424.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(5372..7495)
                     /locus_tag="ACG84X_001552"
     CDS             complement(5372..7495)
                     /locus_tag="ACG84X_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFP9127425.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(7500..9947)
                     /locus_tag="ACG84X_001553"
     CDS             complement(7500..9947)
                     /locus_tag="ACG84X_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9127426.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(9934..10323)
                     /locus_tag="ACG84X_001554"
     CDS             complement(9934..10323)
                     /locus_tag="ACG84X_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFP9127427.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(10383..10886)
                     /locus_tag="ACG84X_001555"
     CDS             complement(10383..10886)
                     /locus_tag="ACG84X_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFP9127428.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(10899..11123)
                     /locus_tag="ACG84X_001556"
     CDS             complement(10899..11123)
                     /locus_tag="ACG84X_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127429.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(11227..13137)
                     /gene="ltrA"
                     /locus_tag="ACG84X_001557"
     CDS             complement(11227..13137)
                     /gene="ltrA"
                     /locus_tag="ACG84X_001557"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFP9127430.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(13883..14020)
                     /locus_tag="ACG84X_001558"
     CDS             complement(13883..14020)
                     /locus_tag="ACG84X_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFP9127431.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(14017..15201)
                     /gene="mobT"
                     /locus_tag="ACG84X_001559"
     CDS             complement(14017..15201)
                     /gene="mobT"
                     /locus_tag="ACG84X_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFP9127432.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(15460..15750)
                     /locus_tag="ACG84X_001560"
     CDS             complement(15460..15750)
                     /locus_tag="ACG84X_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127433.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(15740..16882)
                     /gene="dcm"
                     /locus_tag="ACG84X_001561"
                     /pseudo
     CDS             complement(15740..16882)
                     /gene="dcm"
                     /locus_tag="ACG84X_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(16958..17122)
                     /locus_tag="ACG84X_001562"
     CDS             complement(16958..17122)
                     /locus_tag="ACG84X_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127434.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(17115..17789)
                     /locus_tag="ACG84X_001563"
     CDS             complement(17115..17789)
                     /locus_tag="ACG84X_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFP9127435.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(17867..19207)
                     /locus_tag="ACG84X_001564"
     CDS             complement(17867..19207)
                     /locus_tag="ACG84X_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFP9127436.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(19290..19625)
                     /locus_tag="ACG84X_001565"
     CDS             complement(19290..19625)
                     /locus_tag="ACG84X_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFP9127437.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(19635..20009)
                     /locus_tag="ACG84X_001566"
     CDS             complement(19635..20009)
                     /locus_tag="ACG84X_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFP9127438.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(20022..20336)
                     /locus_tag="ACG84X_001567"
     CDS             complement(20022..20336)
                     /locus_tag="ACG84X_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFP9127439.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(20449..23676)
                     /gene="fss3"
                     /locus_tag="ACG84X_001568"
     CDS             complement(20449..23676)
                     /gene="fss3"
                     /locus_tag="ACG84X_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFP9127440.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
BASE COUNT         6657 a         5142 c         4108 g         7896 t
ORIGIN      
        1 ttgaatatca tagcaatgta tttgaaaagc aaattggaaa acaaataggt gcaacaccat
       61 aaatatgaaa aaattgggaa aaagtagaat ggaaatttgc ttacgtctca cgagatagct
      121 cacactatta atctgaagaa caatgaagtc gacttttaga aattgctaga agaaagtaaa
      181 gcgaattatc actagttact atagagtaag ttcaaataaa gcatctccaa cttacatggt
      241 tacatgagga tatcaaatcg aaattactca agcttcctat ggctagagtc gcgagaagtt
      301 gttgggcagt agacataggt tatattgttc ttagctacac gatcattaga aaggaaatcc
      361 tattatgtat agttatcaag aagatgcaaa agtccaaaaa aatcgctggt ggattttgat
      421 tgctatatct atgtttacct tcatgtccac attggatggc agtattgtca atattgcact
      481 acctaccatc tcagatgata tgggcatacc aatgaatcaa gcggaatggg tagtgtccgt
      541 ttatctgatg attgtctgtt cttgtttgtt gctgtttggt aaaattggcg atagccgtgg
      601 gaaaatcaaa gtatttcgga ttggtacgct gatctttgtc ttgggatcgc tgttgtgtgg
      661 gttcaatcat tcgctaggta ttttattgtt cgcacgggtg gtacaagcca ttggtgctag
      721 tatgactatg gctacaaatg ccggaatcat cacggaagtc tttcccatac atgaacgtgg
      781 tcgggcattg ggagcaatag gtgcgtttgt ttcattaggc tcgattgctg gaccaggtct
      841 tggcggcttg attttgtccc aattttcttg ggcgtacatt ttttggatca atgtaccggt
      901 gggaatcgta acgatgttga ttgctgaaaa attcttacca aaagatatca ccatgagcgg
      961 ccatacaatc gatggagggg gctttgctgc cattgcggct acgattatca gcttttttgg
     1021 agcaatcttt ttggggcaag aaagtggctt tttccatcca gtcccccttg tactgttcgt
     1081 aatttcagtg attgcctttg tcagcttttt aaaagttgaa aagaaagcag cctctccatt
     1141 gatttctttc ggtattttta agaacaagat ttttaccatg agcttgatta cagccttgtt
     1201 gattttttct tccaacttct ttgtcaatgt agtgattcct ttttatctgc aaaatgctcg
     1261 cgggttgagt cctagctatg ctgggctgtt gatgatggtc tttcctttga tgatggtcgt
     1321 cggggcgcct ttaagcggct acctgaccga ccgggttggc ccggagattt tggtattagt
     1381 aggcttgggc ttattgtcgg taacccaggt catgtatatg tttttgtcag tggactctcc
     1441 tttgtggcta tacattgtcg ctactgccat catgggtgcc ggcaatgcct tgttccagtc
     1501 ccccaataat acgatggtta tgagctcggt cactatcgaa aacttgggac tggcaggctc
     1561 gatgaattcc tttgcccgaa atttggggat ggtcagcggg atttcgcttt ctacgacggt
     1621 cttatatcaa gcgatgtctg ctaagatggg ccagcaagta actaactata tcgcaaatcg
     1681 gccggatgtc tttttatatg gaatgaagat taccttttta ggcagctttg ttttgtgttt
     1741 tgttgccttt ttcctgacta tctggcgtat caaaaaacaa ggaggtattc agaaaaatgt
     1801 ctgaaaaaac cactgttgaa gaatttttgg aggcctgcgt atgggtgagt gggatttcca
     1861 tggatgatgg aagatgaagt gaacttctaa aagccgaaaa actcaagtat tatcttcaaa
     1921 atactagtgc tcaatgagat gcttgatttg atcacaagaa gactgcgaaa gccgctggca
     1981 accgcaagct aggtatccca ccgatggact acgttttaga ggctactggt tatgaatacg
     2041 gagccaacgc tctcatctgc ataagaatac atcacccaga ttatgtaaag attttcgata
     2101 cttctgtcaa aaaatcatta agatagataa atgatttccg tctagtcaaa ttggttcaga
     2161 atgtagacac acagatggta agaagtcact cacaattcga gaatggactt gtcctatttg
     2221 ccgtatacat cataatcgaa acgtcaacga tagtatcaat attttgacca agggctatga
     2281 atacaagcat tgccttagaa aacatcaaga accttaggaa caacggggat agcttggtta
     2341 ataagagata ccgctgttta ggcttgcaag tatactcttt tatcaagaat tccgtggctt
     2401 tagtcatgag aggcttaata ctatgaaaat tttctttagc atttttgatt taggttcctt
     2461 ttctaattat aataagatga ccactacagt aacctactga aatatataaa cagccactgt
     2521 agtaccattt tcaaagtagt ctatgagagg agaatcttca ttcttatgaa cgctggaatt
     2581 gcggatatga atttaataaa aaaaaccctt aatgatttta cttccaattc aatatcaaaa
     2641 ggtactggta tcaatttaag cacaataaaa aagctgaaaa gtggtgaaag atcagtggaa
     2701 aagctgaatc ttttagatgc tataaaaata acggaatttg ctatgaaaaa tggaaaagct
     2761 gagattgaaa tatggagata attatcgtct agtgaattac ttgccactta gctgaattta
     2821 acgatccttg gtgcttgaag ggggagattc ttgggaatag agcatacttg caagcctatg
     2881 tctttactaa caacgatatc tcttattaac caagctatcc ccgtagttct aaggctttta
     2941 cttttatcta agcaataatc gtattcaaag gaaatttttg acccttagaa agtctcattt
     3001 tatcagacgt gagcttaggc attgctgaat tttgttaatt cggttttagg ttgtgctttg
     3061 agcataatat gaaagtattc tttatcacga tttcattcat ctaaggtaat gtgatgtgat
     3121 tctgaaattc tttcaaaggc agtttttgca taagctgaca ttacatcatc aatgacatgt
     3181 ttacaatgtt tcactactaa aataaggggg taaccaagaa gaaaaactga atgattattt
     3241 gtatctaatt ccatggtata tcaaccattt cctatataga ctgattatga catggattaa
     3301 aataaaaagg cactatgtct taattgtcgg ttttcgagtt accgaatggc attcatcacc
     3361 cacctataga ggatgggcga cttctgcctg aaataagtta cactacttat aacttctaat
     3421 aaaattagat tgagtcatta ttatttaaca tcaacgattt tccagtttcc atttttttgt
     3481 aatactaatt tgtactgaaa gtagctagtg gtttttgata cattatcaag gtattttatc
     3541 tttgtactca ctagaaaatt ttttccgttt tgtagataaa ctggattctc taactccgaa
     3601 aactttaagt caatattgat tggtcgcatc gcaccatttt caacataata ctccaattct
     3661 ttttcagaag ctgatggata aagtttaaaa aatgtttcta aaaaatcggt gatttcttcc
     3721 gttgttttgg catcaatttc tgaatcgttt tctacttgtt ttgcttcata ttttgccttg
     3781 tctggctttc caatcattgt tggcaaacta gttactaaat gattcctgtt ttcatcttca
     3841 aagattgtca ctcgatatgc agaagaaatt gattgcgtct tttttccctc tgtaatatgt
     3901 tgctccacta aaaatgaaac gacaaattct tccgagtgtt tttcaacatc tagaattttt
     3961 acagattgaa cttcggaact cgtgggaata tctgctcgaa ccatatcttg gattaaagcg
     4021 agaccgtttt ctgtaaggta ctgttcgaga ttactcattc tcttttcaat tgcttctttg
     4081 ttatttttcc atgaaaaata ttctttcgca aaatcctctg taaaactttc aacgccagaa
     4141 gtattcacta ccttctcttt tataaccact ttttcatgag ttgtatgttg atcaatggcg
     4201 gtgaaatttt tataaacgcc aaaagcaaga ctacaagaca ataaaagcca aagggcaagc
     4261 accatttttc gatgcttacc cacggataca actcgttctt ttttcttttt tgggctcttt
     4321 tccttttgat tccgttcaat ttttatcttc attctttttc ctcttttctc ttatttgtat
     4381 cggccagctc cgataagatg ctgccgccaa tagttttccg ttagattcgt ccaccccact
     4441 ggatctcctg catgaaacat gcgattctcc cctgcgtaaa tgcccacatg ggtcacataa
     4501 gtaccggcat cataggttga atgaaagaaa actaaatcac ctggtttggc atcttttaga
     4561 tcaatatgag tcatggcatc atattgatcc tgagccaccc gaggaagttt caggtcaact
     4621 ttggcataac accattgggt caagccacta caatcaaacc ccgtttctgg acttgagcca
     4681 ccaaacacat aggccgttcc ttcatactta aatgcctcat caaaaatttc ttggactatt
     4741 ttgtcatcaa actgagttgt agttaggtat tgcttcacta ataaacagta aaacatattg
     4801 ccataattat accgccaccc accattttcc ttaatcgcga ttgggttggg gtaatcgact
     4861 ttttgaccac ctgatttttc ctttgaaaaa gattcagcta aagcaaaact atgcttcttc
     4921 ccgtttttcc cgacatgatc tagatacccg ccaccatagt tataggcctg aataatacta
     4981 tcttgatcac accctagttc tttggaacgc ttaaccaaag acgcaaaata gagacagcct
     5041 tgtttgatgg atgcctcggt acttaatgaa ttaggtggta atccggctga ctcagaactt
     5101 tgcataacgt cttccattgt gccaccagat tccacttgaa taatcgccaa aagaattgga
     5161 atatactctg ttatatccga ttctttggca tacttttcca ccattgcacg gtgtttcaat
     5221 acttcttctg agacactagt tccgccagga gaagtgccag aactaccatt tccctcactg
     5281 tcttcaccaa acaacaaacc cacacacatc aaaataccca taaaagagat ggtcagaaaa
     5341 gttaatgaaa taacacccac tttcttcaag ttcatttttt ctcacctgac cttgattttg
     5401 gacgatggtt cattcttttt tgtacttttt gattggtctg ctttggcaga gtggacctct
     5461 gtttcacttg ttggaaagaa tttttcttac ttgctgattg gcttttccct tttgaaatga
     5521 tttcttgact agttagtttt cgtttgattt cgggattcag atttgctctc acaatccgct
     5581 ttggtgcttc ttttttcagc atcatatctt tctgaggttg agctgcttta tctattggaa
     5641 tattcgccct tctttttccc tgacgatttg ttgcttcact cagtatcttg cgtttttcgt
     5701 ccattttcgc atttcttcgt tgtcgttgtt tttctcgcaa atccactcga tccgcttttt
     5761 cttggaacag tccgcgcttg aattcttctg gtgctttttt cgacttttcg attcctttat
     5821 ggagattgta tttcaaattc gttggcgtat tccttacctg atcctttact tgtttagtct
     5881 tatctttcac caaagcttgg gtatccaaaa ctttgccgat ttttctccca gccaaattca
     5941 ttcgggattg tttcttatta tttgaaactg gattctcctt agttaagtca gatagtattt
     6001 cgtgatcgtt cggtaatcgt gaattctttc gtagagaaga accggatggc ttaaatttgg
     6061 attttgattg ttcctttgcc aacttatttc cgactgctgc accaccacca aaagccaaag
     6121 ctcgtcccac atttcgattg agttgccgca attttcgatt cattaacatt tgcggttttc
     6181 gcatgacgcg tcttcccatt gactggctat cattactctg gaggttgaac atactcataa
     6241 tgtcgcccaa tttgaaatag ataccggcaa aggtcacaat ttgcagaaaa gcaaccatga
     6301 aaaatggata ggttgccgaa atattgaaaa acatcgtgga gatgctaaat gcagtcgtaa
     6361 tcaccaaagt aacacccgct cgcatcataa tcgtattgaa taaacgaata atcgccttct
     6421 ttcctaaact ttcataagtc ggcaacatgg acaataagaa actaattggc agaaacatcg
     6481 caaagataat gaagagaatt tgcgagaaca acataatccc tgttagaaga aaaacaaaga
     6541 aggaaatgcc aatattgaac aataccaaaa agaccacggt ccctaaacgg ttcatggtct
     6601 tggtaatact gagattcgca ttgtcattgt cttcaatctc tgccttgacc gcttcttccc
     6661 gatctttgcc tttgttttca tctggactca cagatagaat cttgttgacc cggtcttcac
     6721 caatttcttc tatgttggaa tcatcaaatt gcagtagtaa ccaaggttgt tggacttgaa
     6781 tcgaaaacaa actatcccga atcaaatcca cactatcttt tccttggctt tctgaattgg
     6841 gtacaacgat ctcggttcca agggtaaggg ccgcttcact aacatctgag ctaaagtcat
     6901 tgatttttgt gatataggta ggcgcataag caatgaacga acccgatagt agaaaaatca
     6961 tcacaaaatt aatcacggct cgaactgctt tcgtggtttc tcgttttaat aatccggtat
     7021 acgccacata cacccccaga gctaaaatca tcaataatag aaacccaaaa taaaatccgg
     7081 aggtctggag tccattttca gtaataccag ccaatgtttg gatattcttt ccaatacttt
     7141 cagccgtatc cgaaatgaaa tctaatttgt aagcctcttg aaccacataa cccgtggcgt
     7201 tcgacaaata caaactcacc gtccaaatga aattagtaat ggcataaaga ccatacatca
     7261 cgcttttccc taagccatca ccccaattcc aaggcaacca atcccaagag ctatccacaa
     7321 agaaatctag ttgatagttg ttcagtgaat atttggaata tagatttcct gcttcaactg
     7381 tatcatcaac tagccctgtc gcctcggcta ccgtaccaac taaactcaat agaactatca
     7441 gagtgagtat gctaataaaa acgattccca caatccgaaa aagtttcttt ttcatcccct
     7501 cactccattc tctcttgaac aggtggacgg gtatcaaagg catggaagag ttcttcaaag
     7561 actggatgta cctgaaccac gcctacccga ccatacaaat cctgcatcaa gcattggcca
     7621 ttttccaaat ctcgtaggcg tttttgattg ctttcatctt ctcgatccaa gccaaagaat
     7681 tccaaggttt tcttgatttc atgaatatcg gtactgcgaa acgcaaactt caacccgata
     7741 ttattcttca agcgttcatc cagtaaatca tcactatttt gcgtgacaaa gtaaaccccg
     7801 gcattcatag cccgcccagc acgaacgagc ttattcgata atgttttccc ttgcgctact
     7861 tgaagaaaac tccacgcctc atctaagtct acaattttga agatttctcg attactatgg
     7921 ataaagtcca aggcaaaagt ggaaatgacg attagcatgg aaacactaag caattccatg
     7981 gtggtatatt cttcaaaagt ggtttctgca tctggtaaaa ccaaatccgc tacttgaatg
     8041 atatttaact gcctatctaa actaatcgac tgggtaatcg aaccatctga gaaaagcaaa
     8101 tgggcaaaat cataatcggt aaaggactcg atgtgatccg cgatattttc cgcaactggt
     8161 gagccttctt ttcgaagctc attaattact tgtaataatc cccgttgatt gctttgggta
     8221 accgtccgaa tggccttacg caacactgga aacttctccc catctcgact agaaattcct
     8281 gttaaaaagg tcagaatatc aattgctaga ctttcagaat ccttcttttt ctccataatc
     8341 acataaggat caagtaatcc ttgatttttt ggcttactag ttaagttgag aatattgatt
     8401 tcatccgcaa tttctggcaa ggtttctttc cagccacccc gttccccttt tggatcgaca
     8461 atcacagctt gtccaccaaa aaggacggcg taataaacta agagattgtt actaaaggac
     8521 tttccgccac cgagtgaacc gaggaatgcc gctgctagcg cattggtaac tgaatccttg
     8581 accccttgtg aggccaatgc cggtttcagg taaacattgc gccccgtatc tacgttataa
     8641 ccaaagtaaa tgccttccaa ctcccctaac atctgagtgg cgccaaaacc aagtccggcg
     8701 agaaaatcag acgtaacata ctggatataa tcattcatgt atcgcttact agaaggtaag
     8761 aattcttcat gtagccccat catatcgcca aaaggccgga ctagttttac attggtatca
     8821 tcataaaaat ctagcacttc atcacaccgg cgctttagtt catctactga ttcggcactt
     8881 actcgaacca catagctcag tttgtacatg gattctttgg actgatccaa ggtagtttcc
     8941 aattcatcta cggaatccaa tgcatctaag acattggaat ttgtttcatt gtcagattga
     9001 taggcatggt tgtccaagtc ttttaattcc tttttcttat tgcgaacggt agcaagtgcc
     9061 tttttgttcg tcacaatctc cacattcata ctagtgtcaa ttgggaatgt aaattgttgt
     9121 tgctggtaat agaaaagttc tgaggaggga aactccattt cccccacaat tgtattaatt
     9181 gttaagtacg ctacatatga ttcatgattc tcatgttcca tgcataagta ccggggcttt
     9241 tcttcaatca aacaacgact gggacgtaat aagtcgtaac gtttcaccaa agtttccgac
     9301 ttcagctttt tctttggtag ctgaaattca tattcttcaa atggtgtacc cttttcgcca
     9361 tagatatgtt caatcaaata catcagatca ctcggtgtga ctcgtctgac tttaaatctt
     9421 cgagccaatt tactttccat tagtttttca agcttggtat atcggcgaat ttcttcattg
     9481 gataaggaaa caaaatcgcc catcaaatga tgattcactc catagacaaa ttcttgaaag
     9541 ccggagaaga aagatttctt gagattcttt agattgacct cttcatctgt cgcaatcagt
     9601 ttgaagccaa taaaaaagcg ataatcaatc tgactatcgc caatcatgga tactaatgcc
     9661 tctgtctgta aatcaattcg ttgtttcgct acttctgtta atcgcccggt aatttccttt
     9721 tttgatcgtt cttgcgtggc acgaatacta ctttctgtgg caatttgtaa ggcatgaatc
     9781 ttgccttcac gattttgcgc aatcaattga cgaaagttat cgtggacttg atatttctgt
     9841 tcaggtgaca aaaaggagta attgtaaggt attaactcat agtaggcaaa acattctccc
     9901 tcttgattaa agacaagatt attttcaata tacttaatcg ggtacatagt tcacactcct
     9961 taccagagta atgggttcgt cccatcgttt cttctgttct ttgactttct ttcctgcgaa
    10021 agtgacctta aatcgtaagt gatagctaat aaaagatcgt aaaaatccca atggtttctt
    10081 accgtcaaac gttttttgcg acatgaacca agtaactgcc accggtatac ctaagtattt
    10141 taaaaaggcc ccctctatca tagatagtgg aggcacatgg gcaaatacga tgacaaacag
    10201 caaggataaa acaaaccaag ccatctggtt aaaagtcaca ggaaaaggca gttgaaagtc
    10261 attaattgca taaatgacct tttcaactgc ccaaatactg gtgtagcttt ttattttctt
    10321 catcaaatca ttcctttaaa aagaaggata gtttagaaat caactaccct tcaataattt
    10381 tgttaatatg gatactcaaa aacacctcga ctcgttacca aataattgcc tccaatctcc
    10441 aagtctctac cacacgcatc aaaatcaata tacgtcttca agtgttctgg tacttctcca
    10501 aaatcaccag cttctacaat caagaaatat gctacatcac tcatatcatc gcaatctgga
    10561 taatagataa tatcatccac atgctctacc atctcctcaa aagaattgaa gaaagcatgt
    10621 tgaatctcag aagcaacttc accaactggc gttccttcaa gttcctccgc taagccacac
    10681 aaccgattaa tttcctcaat tggcgtatac tcatcaatct caaagggaag ttcataatca
    10741 tgaattgcat attcctcgta ttcgtcattt aacccaattc gttctttcac ttcatcaaaa
    10801 tcgacaggtg gggtaaacca cgcccccacc aattcacctt cgttatattt cccgaggttc
    10861 gcaatataaa cacgcatctg ttccatcgtg cttccccctt acgcaccgac aattcggtta
    10921 aacaaactga gtaagacatc cttcacccca gaagcattaa agaccaatcc gaccgcaatc
    10981 aaagcaatca ccaaaaagcc aatcagtttg gaaaactccc gcttaaatcc taaaaacaaa
    11041 ccaatgacca caattgccag taagactaag gattgggcat tggttaaaaa ccattgatat
    11101 atggataggt aagttcctga tattataaat atctcaaact tttcccccca ttcacacgga
    11161 gcgtgcgact ttcaccgcac tccgcgttcc atcgtgttta tattgaaaag tatttatgta
    11221 gtagacctat atcaagttta attcttgatt gccagctaat actctatatt tatttagtct
    11281 tatgagctgg actttattta gcttcaatag agctatatat ttttgtattg tttcttctgt
    11341 tttagcgtgt attagacggt gtaccgcctc ttttaccaaa ataagatttt tataatcgtc
    11401 atttccacca gctccagttg gtacaatatg atgacaatgt atttcattag cttgttgaaa
    11461 ttcttccaga gttatagcac attttccatg ttgagcagaa aatagcgaaa ttcgattgtc
    11521 tgcgtattct attgtgcgat tttccaaaga taatttcatt aactggtaca tcagtaattt
    11581 atcaacactt agattggtgt ggataaattt tcttccctct agagtgtagc aattcgctaa
    11641 atacaccttt gccattggtt ttctgtgttg gatatatcca acagggaaaa taggttcgcc
    11701 ctcgccagca acataccgaa gcattttaga tttaccatat cttgttgcct cctttgtcgt
    11761 aagttgtctg cctgtttttc tcaatctgcc ccttttgttt gtacctaatc tgttagtgaa
    11821 gatagccatt acagctctat tcagtttcat acaatccaga tttacattcg ttgcaatctg
    11881 ataataattt tgcataccta ataccattga attataaagt cttgtttctt ctaattccgt
    11941 tttccctttt gagggagaag caattttctt tgcctgtgat accagcttgt ctttttggtt
    12001 tttgaattgt ttatcactta tatgtgattt aacaactaac ttctttcttc tcggtatcat
    12061 tttaatcttg aaaccaagaa agtcggagta tctttttcta acatttacaa ttcttgtttt
    12121 ttcttgtgat acttccaatt ttaatcgttg ttcaatccat tgagtgattg ctattttggc
    12181 tttttcagca ctttccttgt agcggcagaa aactctaaaa tcatctgcat aacgaaccat
    12241 atacatttcc tttaactttg ttttcttcat ttctttgtaa gcgttgcttt tacatgggct
    12301 accgctttta ttgatatgaa ccacatagtt ttttgtaaca ggattttcct gccattggct
    12361 ttctacccaa tggtctaact cattaagaac aatgtttgct agtagtgggg atattattcc
    12421 cccttgcgga gttcctttct ctggatatgt tattgtaccg ttagtcattt tgattggagc
    12481 ttttaatatc ctttttaaaa tgaatatcaa gtgcttgtcc cgtattccca tagcccatat
    12541 ctgttttatc agcttggaat ggttcacgtt gtcaaagaaa cccttaatat caaattcaat
    12601 cacataatgt agctggctga tttgtaggcg gttataggtt gcttttattg cattttcaac
    12661 tgacctatta ggtctaaaac catagctgtt ttcactaaat ttagcttcgc agattggttc
    12721 taatacttgt tttatacatt gttgtataag cctgtcccac atacaaggaa tacctagagg
    12781 tctggtttta ccatttggtt ttggtatttc ttttcgcctc actggcttag gtcgataccc
    12841 atgtggactg cctgcaacaa tgtatcttac ttttttgaca actgtttctg ctggcaattt
    12901 gccaatatct ttaattattg taccgtctgt tcctgctgtt ttactgcctg catttgcttt
    12961 gatatttcga tatgccagta atatattttc tctcgatagg ataatatcca taagatgagt
    13021 gaaaatatct ccattcttac ttttggcata taaatcatca aaggtgtttt gcatttcgta
    13081 atattcagcg tgtcttaaat cttctacaca caatgtttca tttttatttt taggcataag
    13141 gcttcactcc tttacttgaa attgagtgag cttttttatc ttactcgtaa tccttattga
    13201 aacaacataa tacttttcta atatatacac gacttgaggg cattcctcca ttctcattac
    13261 aagaatttct taggttcgcc ctctgctttt cagcattagt tcaactgctt attgttcttc
    13321 gtcagtttat tctcttgatg agaacccaat acctttcctc gttccgataa tcttatctat
    13381 acatatatat ccttaggtca ctagctataa gcctgctggc ttgataccgc ctgtaacgtt
    13441 atatggcatt tcataaccta tattcttact ttgccacacc agctacgatt tctcgtacct
    13501 ttgcatttct acaaagttca aatttagacc cgtacattcg ctgtttcgtc agttccttat
    13561 agaacattct aaccatagat attttataga cccccgacct gttggatacg ctacccacct
    13621 ctggatagtt ttcgatagaa gatatatgtt catcaactat tacggtatct ttcagccgtc
    13681 tttaccgagc ttcaaacatt ctgagtttcc tcatacaatg cttgtcggag gctcagggca
    13741 ggcgtttcag agcgttactt catcattcca cctgtcagat tatcagttct cctaataacc
    13801 aaactttttc gttcttttat tagtgcctta gcttttcact aaggaacgag tcgcacataa
    13861 attttgtccg aaattcatct tgtcactttc ctttcttttc cattgctcga tccgctgctg
    13921 cacttgcatt catcaagcac atcacagtaa caccaagcat actgccacca aataccaaaa
    13981 aaatatcttt tacaattccc atgacgattc ctcttttcat ataatcaaat tttcaattgc
    14041 catactttgt tgctccaaaa tctttttatg tcggtctgat aagcgtgcat tctgtaccat
    14101 atcctggata taggttgtcc gattcaatcg atccaactcc ttagccattt tccacgtagg
    14161 ggcgacttgt cggcctagcc aattcaaggt tcgttcaatg gtatacggtt ttggctcgga
    14221 agttaattga atctctttcc gattccgtcc aataaaacgc ccccattgtt cattcaaggg
    14281 ccagttggtt cgccttttac cttctacttt atccgcaaat cgcaagtaac gattgataat
    14341 ggaaaacgtg gtgctctcaa tgctacgacc ttttaacaaa tcttgaatcg catgaaaagc
    14401 acggtcattt ttcagtcgaa tctcaaaacg atttttcgtc tcagtttggt ctaatggaat
    14461 ccctaacttg atatattgtt catagtcttt ttcatacaaa cagaaataaa cctcactctt
    14521 gagactgccg atatataagg tattgcccat gccgtccttt tcatcagcct ttaaaagttc
    14581 cccggaacga taacttttaa aggtacgaaa caaggagata cattcttcct tctgacattt
    14641 tttcgttagc tcaggtatat ccaatagccc cactcgatca ttgattgcca agtccaagcg
    14701 tttcatcacg ccaccggcct ttagacaatc ctcgaaaaag tcgtaccagc tacgcttttg
    14761 agcgagtaaa aaagtttcaa attgtcggca acctcgcccc tttaattcta aaagcacacc
    14821 tttatcttct tcatgagaca acatcaccac aatatcaccc atgacatact gttcttgata
    14881 ggagtaaaag gcataatctt catggagcat atactcaaat ttcaaatgga gaatttcttg
    14941 aataattttt cgtgcatccg ttgtgggaaa gcgaatcctt acatagtcaa acagtaacgt
    15001 caaaggcaaa tcgggattaa agctttccag ttggtcaaaa attttcctca tggtttttat
    15061 agatgcggtt acgccaccat tttctatctg atttaagtac ggccgactaa gtccacaagc
    15121 cgtagccaat ttattttgtg aaacgccgta ttcgttgcgt cggtctttta atagccgata
    15181 atctaaattc cgttgtgcca agttctcacc tccaaattca aggtgttaac tttttcaaat
    15241 gagttaacac ctatacaaat tacttactat ctttgataca acaagcattc ttaatggttg
    15301 cttacttatt ttttgtgttt ttgtaccccc ctgttagata cgggggtgag acatcatggt
    15361 cggctaacgc cgtccatgaa caggcacagc accacggagg atttctgctt cgcgaatcct
    15421 ccgcggtcag cgcctaacag tcagttgtgt tggtttaggt tactcatctg taataccatt
    15481 tacttccaac tctgctttca tttctaacaa gtattgacga atatctggtt cttttgcttg
    15541 gtccgcaatc cgctcaaatt ctgcaattac ttgatttatt tcaattcgag catccgtctc
    15601 ctcattcatt aaatatggat cgccagcgac tttgacacca ttcttgcgaa tatcaaattt
    15661 taaccgtcgc aattgttctt ctaattctgg gtctgactga atctttccaa tcacccaata
    15721 aatttctcca atcaactcat cataaaccat gtacatccaa ctcttttaat cttctggcaa
    15781 tatcaaaaat gaccggaact gttacagagt ttccggcttg cttatacaac tgactatctg
    15841 aattgacttg agaatctcga tcaaaagccc aatcgggaaa gccctgaagt cgccaacact
    15901 ctctaggtgt tagcttccga atttgatact gatccgtgac gatcgcttgt tggtctcctg
    15961 ttagtaaggt atgaacactc tgttttccca gacgacctcg gcgacttgtg gaattaggaa
    16021 aagccagatt cacactgtct tctggcttca cctcttgata ttctgtttca ttttttcgaa
    16081 tcatgatttt tgtaccacct tgtttcgttg acaaggtggg ggcggttcca gtaacttcat
    16141 aaactcgatt accttgttca aactttcccg gtaatagtcc tgctacagag attccatccc
    16201 ttgctggcag tgcgattttg attccttcat cacctgttaa ggttggcgct acgccatctg
    16261 aaccatagac ttgtccaccc attcctcgat tggaaggatt gatatttacc aaatttctga
    16321 tgttttgatc agatgttgaa gacggtccaa tgataggaaa tacttgttcg gtacatgcgt
    16381 ctcgagaatg tccgataagg aatatccgct cccggctttg gggaatgtag gcctttgagt
    16441 taagcaccta ccactccacg tcatacccca atccatccag cgttcggagg atcgtctcga
    16501 acgtagcccc tccttcgtga ttgagcaatc ctcggacgtt ctcaaggaat aaaagcttag
    16561 gtcggagaag agtggtgaac cgagcgattt caaagaataa agtacctcga gtatcggaaa
    16621 atctttgccg ctttcccgca attgaaaaag cttggcacgg aaatccgccg caaaggatgt
    16681 ccactggtcc gagggattga ataaactcat ctgatacact tgtgatgtca tgcatttcca
    16741 cctccttact tgtatcatga attgctttat aactacgtct agcaaattta tcaatttcac
    16801 aaaaaccgat acaatgatgg ctcgcctgtt ccatacctaa acgaaagcca ccaataccgg
    16861 cgaataaatc taaaaatctc atacattacc tcattcattg caaagaaaaa agccaagaac
    16921 attttgctct tggctcatac attattaatt tgtcctacta ttttttattt aatccaacta
    16981 atttccgttg tttttcattg gcctgatcgg ctacatattt aatcaccgtt ttgaactctt
    17041 ttgcagtagc attttccgat aaatccgcaa tgctcttatt gtatttcttt acaattttcg
    17101 ttacttgttc tttctcagtc atgtaattga acctccaaat ctttcctact ataccctagt
    17161 ggtaaaaata attctagatt atccgtagca taatgaactt cggaaatatt attcgtataa
    17221 tcttttatta tgatatgaag caatacatct ggatgtttac tctttacttt tgcaatgttc
    17281 tctcttgatt tgaaaaaagc gttaataaat gcctttttcg gcacatgacg tccctctgca
    17341 atttcacgtt cttgtgtaaa tttccaagcg attttagggt cttgataaac atagaaaatc
    17401 gtcactcgaa aatgtttttt caacgcccgc gagatatttt tttcagcact taatattgca
    17461 aaagttgcat ccagaataaa agaatagcca tgatctaaga catatctaaa tgcctgctct
    17521 accaaccaag aagatgcttt ttgaaagaga ctagagtttt ttccattata atcaggaaac
    17581 tgggtgcgaa agtaatccgc atcaataatc acatggttat cataattctc agctaatcca
    17641 atggcaacct ctgattttcc agccccagga ctccctgcca taaaaactgc gtctcgtcca
    17701 acttcggggg atttcccttt gataatataa gaaataaact tatccttatt tgcttttgca
    17761 tactctaaat aagaatcatt actttccata ttaattatcc cctttcttcc tactatataa
    17821 aagtattata cgttacttga agtataaagt cagtattgaa gatcactcaa tcattcatct
    17881 tttctaattt actaattgaa tctaagaaat catacccttt tggtacaagt ggcgtataaa
    17941 actcactaat cacactgcca cctgtatcca cataacctcg acctttgatg tgcttcataa
    18001 agaagttttt ttcgacctcc ccaaacatca tggaatatcc gagttcactc atacgaccca
    18061 aagccacgcg aaagttgaat tgatcgcgga ttccgtctcc taaatatttc gcatccggcc
    18121 tttggcaagc caaaatcaga aagaaaccag attgacgacc caacatcacg atttgtttga
    18181 gcttattcaa aatcaccgca ctttctttcg tcgttaacat ctccatataa gccacgtatt
    18241 catcaaagat taaaaagttg ggtggaagtc caagataggc ataattctct cctgttttgt
    18301 agttagacat ttctttcatt gccttgctac gagccatcat acgttcatag aaatcttcca
    18361 cacaagcaga aatttcttcc ttttgtgaat aaacatgagg catcaccgta cctaaatcag
    18421 ctaaatctgc atttttggga tcgaggataa acaattctgc atctgacttc aatagtgctt
    18481 cgataatggt gaggaggaaa taggtcttcc ctccacccgt gccaccagcg attaacatat
    18541 ggggtaaaga atcataagcc catacttgat ttttcatcaa tcgcagagtc ccattttctg
    18601 ccactacttc gtctatccca attcgattgg cgatcatatc atacagtaaa gtatactcca
    18661 cataggagtc tttgagttcc ttttctacta actcacaata cagtccgctt tctaacttct
    18721 tttccaattt taaaagctga tcttggtatt tcccaagtga aatttgaacg cgaatagaca
    18781 gtaatccatc tttcattcga taacagattt tggggaagta actgatagtc tctctggttc
    18841 ggctactatt caaatctttg aaaaagcctt cactttgagt ttgtttcact tcataccaat
    18901 ggttctctag aatcatccga gctagctttt gtcgatgcca caagcttcgc caatgatcaa
    18961 gaaaaaagtg aatataaagc aatatcatag ctcctgaaaa agcgagactt ccaagcagac
    19021 atactaaatc ttttatagac caaacgattt caatagtaga aagtgatagc ttagaaatat
    19081 caaattgtct aaactcttga aaataaaaga cgctcatcca accgatgaac agagcgagta
    19141 gccagccaag aacaaagtga taaaccaagt gctgatctcc tgcgcgtatg cgatgtcctt
    19201 tgtacatttt gatggtttcc acctccaatc gaaaaagccc aataggattt cattaggcaa
    19261 tttcaaaaag ttatgctagt catttactgc tacgaggagg ggagttgttt cgtttcaacc
    19321 aattgattta aaaagccttc aatagcatcc ggcatctcca caccaatttc ttccaaaatg
    19381 gattctgcct gccgacataa gttttcattt acttcgacaa ctataaagaa agactcttct
    19441 tctcctaacc agtctagtac atcagagtct tcttcactgt cgctattttc tccaagtaaa
    19501 ccttgatgta taatcagaaa cattttttca tcagaggtta atgctttaac gagttgttcc
    19561 tcagtcagct cgccttttcc atattgatcg agacaatcta aaatatgttc aacattaatt
    19621 tccataatct tcacctattt ctttctttca ttttggttcg taggatttcc ttgattcggc
    19681 tgccgcttca agactaaatc atccgcctta atgaaccaat taacggtagt tccttctcga
    19741 aaaacataat tggcaacggt atccacgatt ggattgacca actctacctc tgcatcataa
    19801 gcaaactcgc gtaagggtac attagctggg atactaactt gaatcattcg cccttgtgca
    19861 gaggatttta aattataggt tcgttctttt acctcattac caattgttcc atcctcattt
    19921 tgcttccgta cttctcggcg taatgcggaa aaacgcaact tcccaaatgt taaacctgaa
    19981 tctacgacaa taccttctgt taatctcatc ttcttttcct cctatgcttt cactaaatca
    20041 tcaacataca acacgtaatc agtaaaccca cgattctcaa tctcatagcc tttggcaacc
    20101 aaatggggat tcacggcttt tagcggttgg tcttgatcaa aatccttttc accggcttcc
    20161 gcagctacta ccacctcaat atcatcggcc cgttgcttac tggaatacaa atgataactg
    20221 cgaccaatca ccgtagtatt ccgtccatat ccttctgtta taatttctcc ttcaccggca
    20281 taacttaact ttccaaaggt ttcagccata tctggcacga caaatttcaa ttccatcttc
    20341 ttttcctctt ttcattgtta gttttggata caaaaatagc gcgactactt ttttaggagg
    20401 cggtcgcgca cgttggttct taggatttac ttgtatcatc tcatcacctt agttccggcg
    20461 attccagaaa taatagcccg ccgtcgcaaa aatcaaagta aaaccaatga acagtaaaac
    20521 attggaattt ttctccccgg tttgagggaa ggtcttcact gtgggactag attcttgaga
    20581 gccacttgga acagttggtg tttccggttg tttcggcgta cttagtatgg ttggaacttc
    20641 ttttggtgtt aaggtttgag atttttcttt caaatcttca ttgtgttttc cattgatatt
    20701 cccatcttta tcgtaattga tttccgcaaa agtaaacttg gttccttctg gatattttcc
    20761 ggtatctact tttttcgcaa gcacagtttt ggtgaattct ttatcattta cttcataatc
    20821 aatcttgcca gatttccaaa tttctttgtt tgtaccatcc ggtaataaag catacagaat
    20881 tgtttcgaaa gcttcttttg agccatccag tacatcatga gtaatcgaca catcatcaaa
    20941 catatccacc acatcaccat gagtaaaggt ctgagaaccg ttttctaggt gggcctttgt
    21001 ttggatagaa acatggtgtt ccactgtaca actgacagtt tgggcttggt tattcaagct
    21061 aacatccttc gctactggct tatcgcctgc ttcaaaagct tccttatttt catacacata
    21121 gttgaataag acaatagttt tatttaaaac ttgttcggcg gttaatttat gctgaatttt
    21181 ccaagttcct gttttctctt tgttcgccaa cgttgcgctt gtttctgcaa tcaccactgg
    21241 tttggctttt tcatcttttt cttgggcagc ttttgtcgca tccacatcaa tggcttgcgc
    21301 taccacatac cagtcttctt tgatttcatg tagattgtaa ctcaatttat caactagctc
    21361 ggtagaatcc agagaagtta attctttgtt tccgtctttc caagtcgcaa gagaagttaa
    21421 actatcttct tcctcaggca aatcatagag cattaaacgg ttcaaactaa cagaaaatgc
    21481 tttgttcgtc agcttctcgt aaggaacggt caccgtttta attggttgtt tttggtcttg
    21541 ttcggtaatg gtaaagacat actcactctt cacaaagtct tctttgtttt ccttaaaagt
    21601 agaacggatt tctaatggcg taatcttttg aaaaccttct ggggcttcta cttcttcaag
    21661 taaataatcc ccataaggaa gattttcaaa cttgccataa ccatcaaacc ctaattgctc
    21721 gttataagct gtggtcgctt catcttcggc acctgtgatt tcattggtcc cttccaatgg
    21781 cgacacttta aaggtcagat cattgaagcc agtttcggta gtgcccgcag ctgatccagc
    21841 aaatttaaag aaatcaaagc caaagcgaat cacttgttct tttgccgtaa catttcgggt
    21901 aatcacggca tttttttcgc tatcatccac ctttttgatg gatacaggat actttgtttc
    21961 atcaaggcta tatccttcgg gcgcttttgt ttcttgccaa taatactcgt tgatagctaa
    22021 atgtttaacg gcaacttggt tcttttcgtc taaagtcaaa gtgaccgttt catcagaacc
    22081 tttcgttccc ttcgctaact ctggtttaaa agcctcactc catttaacag cttttccatc
    22141 cttagcagta aacaaggtgt attcagcacc ctcaaagact gccttacctt gtgctttatc
    22201 cccagtatct ttgtcttctt tcgtcaaagt ggtttcgcca gtgacttctt gattttgccc
    22261 ttttacgtta ctggtaacag gggctacggt ttgattggca tacttcaatt cgacttttac
    22321 aggtttgaac gtattcacga acccatgact agctttagtt tcggtcacat aataggttcc
    22381 caattccaac gcattagcaa tctcttttgg tgtttccgca tgaccgtttt catccgtggt
    22441 catttcttga acgatttcac cggttggact gtctttgcga atggcaaacg tattaccagc
    22501 taaggaataa ttgtcattcc aaagatcact ccctgtttca actccgcttt tatccagaat
    22561 gatttgccct ttttcccgtg cgttttttga agtcacgtaa atggtttcgc ctgctttaat
    22621 ggtggtagtc atgggggtgg tatcaatcgt ataaggcgcc ggtactgatt tttcggtaat
    22681 ggttactttt gtaccatgag gaatctcatc caatgtagca atgccttctt tgtcagtagt
    22741 cacgtctttt gcaggtaaag tttttccaaa gtctaaatgg aaaaccgttc ctggtacaac
    22801 atcacccgat tctttatcga cttttttgat ctttaaagaa ccctccgttt ccacatcaat
    22861 tttgattgtg taggtattag gtttatcaat cgccccggcc attaaagtct gttggccagc
    22921 ctttttatag gcgacaggtg ttccggtacc agcagatttc ttaagcgtca gcacaccact
    22981 ttcttttgaa ttggcatttg gggtgattat caactgatta ccattcacac gataatcaat
    23041 gtttgcggca ttttccacaa cctcatcgaa ctctgacaaa ttcagattat tcgtatccgt
    23101 cacagtagtc gattgcccta atactgtttt agccgtacta ttatggaagg ttggtttctt
    23161 ctgataatcg tcaatggctt gatttatttt tgcctcaatg gctgcgatat ttacggcact
    23221 accatctgat cgttttattg agtgaagggt atacccatta acttcttgcc agatcatctt
    23281 ctgtgccaca atatgagtat ctgcatctgt acctactttt ttccataaaa cggaaactaa
    23341 tttggcttta tcggacatat ctggtaacgg gtttttctca tagccaggag tgaactcatt
    23401 gtaaatcggg actcctggtt caatacagaa aatatcttgt ttaaagccgt tgtacactgc
    23461 ataatgcgga acagtgactt ctgacattgg acgaccatca ctaaaagttc cttcaacagc
    23521 atattgatgt gctaaatcta gttctacggt taccgtttgt ggatgggtaa tttcatcagc
    23581 aaaagtaatc gtaggagcaa ttgctccaac aattgcttga acagccaaac tcaaaatagt
    23641 taatacacat aatttctttt tttgtttttt atacatgaaa tgttctcctt tcaaattaag
    23701 cacaaaaaaa taagatgctc gcttgaacat ctttgtttat aaagtctttt taaaattttt
    23761 attgactgaa tagaatggat ttgagaatga atgagcctaa aaa
//
LOCUS       DAZKCH010000039        23642 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000039 DAZKCH010000000
VERSION     DAZKCH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.039"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(458..1087)
                     /gene="udk"
                     /locus_tag="ACG84X_001569"
     CDS             complement(458..1087)
                     /gene="udk"
                     /locus_tag="ACG84X_001569"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFP9127441.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1171..1866)
                     /locus_tag="ACG84X_001570"
     CDS             complement(1171..1866)
                     /locus_tag="ACG84X_001570"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFP9127442.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1879..2595)
                     /locus_tag="ACG84X_001571"
     CDS             complement(1879..2595)
                     /locus_tag="ACG84X_001571"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFP9127443.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2925..3533
                     /locus_tag="ACG84X_001572"
     CDS             2925..3533
                     /locus_tag="ACG84X_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFP9127444.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3858..4181
                     /locus_tag="ACG84X_001573"
     CDS             3858..4181
                     /locus_tag="ACG84X_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFP9127445.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4363..5733
                     /locus_tag="ACG84X_001574"
     CDS             4363..5733
                     /locus_tag="ACG84X_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFP9127446.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5863..7164)
                     /locus_tag="ACG84X_001575"
     CDS             complement(5863..7164)
                     /locus_tag="ACG84X_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFP9127447.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7518..9509)
                     /locus_tag="ACG84X_001576"
     CDS             complement(7518..9509)
                     /locus_tag="ACG84X_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFP9127448.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9653..9919)
                     /locus_tag="ACG84X_001577"
     CDS             complement(9653..9919)
                     /locus_tag="ACG84X_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFP9127449.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10429..12555)
                     /gene="pnp"
                     /locus_tag="ACG84X_001578"
     CDS             complement(10429..12555)
                     /gene="pnp"
                     /locus_tag="ACG84X_001578"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFP9127450.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12743..13012)
                     /gene="rpsO"
                     /locus_tag="ACG84X_001579"
     CDS             complement(12743..13012)
                     /gene="rpsO"
                     /locus_tag="ACG84X_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFP9127451.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13263..13826
                     /gene="def"
                     /locus_tag="ACG84X_001580"
     CDS             13263..13826
                     /gene="def"
                     /locus_tag="ACG84X_001580"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFP9127452.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14079..14600)
                     /locus_tag="ACG84X_001581"
     CDS             complement(14079..14600)
                     /locus_tag="ACG84X_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFP9127453.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14603..15445)
                     /locus_tag="ACG84X_001582"
     CDS             complement(14603..15445)
                     /locus_tag="ACG84X_001582"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFP9127454.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15438..16163)
                     /locus_tag="ACG84X_001583"
     CDS             complement(15438..16163)
                     /locus_tag="ACG84X_001583"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFP9127455.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16339..16635
                     /locus_tag="ACG84X_001584"
     CDS             16339..16635
                     /locus_tag="ACG84X_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127456.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      16891..17065
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            17203..18795
                     /locus_tag="ACG84X_001585"
     CDS             17203..18795
                     /locus_tag="ACG84X_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFP9127457.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18808..19548
                     /locus_tag="ACG84X_001586"
     CDS             18808..19548
                     /locus_tag="ACG84X_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFP9127458.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19716..21065
                     /locus_tag="ACG84X_001587"
     CDS             19716..21065
                     /locus_tag="ACG84X_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9127459.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21193..21783)
                     /locus_tag="ACG84X_001588"
     CDS             complement(21193..21783)
                     /locus_tag="ACG84X_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFP9127460.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21930..23282
                     /gene="brnQ"
                     /locus_tag="ACG84X_001589"
     CDS             21930..23282
                     /gene="brnQ"
                     /locus_tag="ACG84X_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFP9127461.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6770 a         4761 c         4502 g         7609 t
ORIGIN      
        1 ggggtgcgac aaaagagctt cttcaaaaaa ataagtcgaa atctcacaca aattcgagaa
       61 ataattttcg taagtttctt cttatttatt gcatctgacc acttctgtta caacctctcg
      121 ttaaacggtg ttcaaaagct tgcatctacg ataataagcc caacccaacg aaaaacgtga
      181 ggagctgttt tatttggatg ctcttatcgc ttgatgcaaa gacagctttt ttacaacctc
      241 tacttcacgg tgctcaatca gctgaccttc ggtattagct caaaaaacgg taaaatataa
      301 acagctattt tccgtttctt ctttttaata cttaggtcaa gatgctgttt tcacaacctc
      361 ttgttataaa taaaaaaaca gttggctggt gactgttcaa aaagcagaat ccttgctttt
      421 caaacggtcg cagtccgttc aactgtttcg ctgcgcacta tttatggttt aagaaactag
      481 ctacttttgt tgtaatcaaa tcaatagcaa cgtggttttc tccgccttct ggaacaatga
      541 tatccgcata gcgcttcgtt ggttcgataa attgatgata catcggttta acaactgtca
      601 aatattgttc gatcacggag tccaatgtgc gtccccgttc ttccatatcc cgtttgatac
      661 gacgaatgat acgaatgtca tcatctgtat ctacgtatac tttgatatcc atcaagtcac
      721 gcagacgttc gtcttctaaa atcaggattc cttctagaat gatcacttct tttggttcct
      781 gaatgatcgt tgcctgactt cttgtatgcg ctacatagtc atacacgggt ttttcaatgg
      841 ctttatagtt cagtaagtcg cctacatgct gaatcagcag atcattatca aaggcaaatg
      901 ggtgatcgta atttgtgttc aatcgttctt caaaactcaa atggctctga tccttgtaat
      961 aagaatcttg ttcaagcatc atgatggaat ggtccgggaa gttgttgaaa atcgcacggc
     1021 tgacacttgt ctttccgctt ccggatccac ccgtcacacc aatgataatt ggcttgcttt
     1081 ttgtcattga ctaaaacctc tttcgtatcc gttttttcat tctaatctat tatagcgaaa
     1141 aaacacgaaa atgctatatt tttctgaaaa ttaatccttt tcaatttcca ataatgaata
     1201 aagttcctct aatgaatcga ttcgataagt aggctggatt tcttcgattt ctggtaattt
     1261 atttctattg aaccaaatcg tatcgatccc tgccatattt cctcctttga tatcagaagt
     1321 caaagaatca ccaatgatca cagtttgctt tttatcaaaa ttaggaatgt gggaaaagac
     1381 atgatcaaaa aattctttca tcggcttttg cgctccgaca gcttctgaga caaagatatc
     1441 cttgaagtaa tcaagcattc ctgcatctgt taatcgccga tgttgcgtgt gcgacacacc
     1501 gttcgtcaca atataaagat cagcatgcgg atggaccttt ttcaggattt ctagacttcc
     1561 tggaacaaga tcatgacctt ggttcaagta gtggcggtag cgtttttcca tttgatcact
     1621 atctactgtt ttcccaaatt gctggaaaag taacccaaaa cgactgccta ttatttcttc
     1681 tcgtgatagt ctgccttttt caaactcctg ccataaatga tgattcaaag ccttatagct
     1741 ggtttcgatt tctggtgtca atgtgattcc ttgttctgca aacaaagcac ttaaagcatt
     1801 ggcttcagtt aattgaaaat ctaacaatgt atcatctaca tcaaacaata aagttttata
     1861 tttcatcttt ttgacctcct atttaaaata aatacttaac tttttcatct ctgctaatgt
     1921 caacgatcga tactcgccta ctcctagctg ttcatctaat tccaatggtc ccatgcttag
     1981 ccgtttcaat gcggtcactt tctttccttg ggctaagaac atctttttga cttgatggaa
     2041 ttttccttct tggatcgtca ataaaaccgt actttggtgc ttgtctgctt tgagtatttt
     2101 taaatcagcc ggcttacatt gatacccatc agcgaatacg attccatttt caaatgctgt
     2161 tacgtctgcc ggtgtcaccc tttcgttcac aactacttga taagtctttg aaaccttttt
     2221 ttctggaagt agcatttcat atcccaattg tccattcgaa gtgatcagca atagtcctgt
     2281 tgtatctcta tctagtcttc ccactggata taatggttgg aaacgatcgg cacttgcaat
     2341 cagatcgatt actgtcgtct tttctggatc tgatacagct gtaacagctt tttcaggttt
     2401 attgagaaga taataggact catttgtttc taagtgttca cctgctactt cgatttgatg
     2461 cagtaaacta tctacatttc gattttgtcg aaattcgact gtgccatcta tcatcacttg
     2521 cttcaaagca aacagccgct tcatttcctt gcgtgtcgtt tctaattttt cttctattaa
     2581 tttatctaaa cgcatgctgt ttcctttctt attactacta attaattata ccttgaatat
     2641 tcttgcttgc aaatacatca tcatagttat tccttgactt aattaacagt tcacgttacg
     2701 gttaaatagt aaagtgaatt ggatttctca tacacagcgt aatgacctgg tggagaaaag
     2761 ttgaatcctg actttctaag gggagatgcg cgcatctctc cttttgcgct tttttaagcg
     2821 ccctgccttc gatgatgtgc acgagattag cctttagaat tcacttaaat aaaatctgtc
     2881 cgttaccaaa gcagacagtc acattttaag gaggaatttt ggttatgtca gtatcattag
     2941 aagtaagtaa aagagaagta cgtccccgtt cattaagaaa caaacttcgt cacgaaggga
     3001 aagttccagc tgttgtttat gggtataaag tagaaagtac ccctatctca ttcgatggtt
     3061 tgacactaag caaattgttg cgtgaacatg gagcgaacac agtcatcacg atggacatcg
     3121 atggacaaaa agtcaataca ttggttcaca agatccaaac gaacactttt accaatcatt
     3181 tcgaacatgc agaatttcta tctgtaaaca tgtcggaaga aacagaagtc gaaacagaag
     3241 tcgttcttgt tggcgaatca gtgggtgcta aatctggtgg agtgttagct caaaacttgt
     3301 atacagtagt cgtatctgct acaccagaca aattgcctga acgaattgaa gttgacgtga
     3361 caaacttgga attaggtgat tctattacag tagccgatct tccaaaaaac gacgattaca
     3421 aattcgtgac cgacagtgaa gagcaaatcg ctgctgtagt cgctcaaagt gaagaagaag
     3481 aaagcacagg tgaaggtggc gaaccagaag tgatcggttc aacagaagaa taatactgaa
     3541 acaatcaggt ggtgttagaa gcggcgggtc agcagctttt aacacgcctt ttttatttct
     3601 aatcgtttat tttcatatgg ggcttccact tttgtaaatg gctttacaaa cgaaaaatcc
     3661 taatttacca agcttttcct cgcatacttt tatcgtacct ttataaaaat ttatactttg
     3721 aaaaaaagta ttcaattatt gttgcatttt tcctgattct ttattagaat gaaccctcgt
     3781 tgaagtaagt atttctagtt tatcctagga ttaattataa aaataaaaca ttcgttgatt
     3841 cgaaggaggt taaacagatg tttgaaagtt ttgatagcag ccgcaaccgt tacgcttcag
     3901 ttggtgtcgt atcaagtttg ccagatgaat tgattgacag tatatggttt attattgacc
     3961 tagatcttaa gggagtcatt ccattagaaa atatattaac ctttgatttg atcgaaaatc
     4021 gtggaaaagt gacgatgcat ttttctcaag caggaagcaa tgtggaaatg gatattgatt
     4081 tgccgtttgc ctattcgaac caatttcctg ctcaagtata cgcctatgat gacggtacga
     4141 gagaaacgat ccttttacca agtgagatta gacaatatta aggtgataga taaacgtgga
     4201 tgtcccttat tttacagacc aggccaagtt gttgattctt tgactcaatt cttggcttct
     4261 ttttatggag tttcataaat tatcattgat ttctaattgg tattctcagg ataaacgcta
     4321 tatactacta actaaatttt aaagatataa ggagtttaaa agatgcgcga tttaacaaaa
     4381 ggaagccccg ctaaactgat tttgatgttc actgttcctt tactgatcgg aaatgttttt
     4441 cagcagttct acaatatgat cgatatgatc atcgtgggtc agacgctagg taaaaatgcg
     4501 ctggcagcgg ttggtgcaac tggaagcctg acatttttga tcattggctt tgcccaaggt
     4561 ttaacagctg gtttagccat tattaccgca caacgttacg gtgcaaaaga ttatcggggt
     4621 ctgaagaaaa gttttgctgc tagtgttgtc attagtcttg tcgtcactgt gattttaact
     4681 gtcctaagtc tcctgtttat tcgtccgatg cttcaattga tgcaaactcc tcctgaaata
     4741 cttgatcaag cacaaacatt tatttcaatt attttattag ggatctttgc atcagtcagt
     4801 ttcaatttgc tttctaatgt cattcgcgca cttggtgaca gccgcacacc actattcttt
     4861 ctgatcattg cggtcatcat caacgtcgta cttgatttga tctttattat ctattttggc
     4921 atgggtgtgg aaggtgcagc tattgctaca gtaatcgcac aagtttcttc cagcgtactg
     4981 tgtctagtgt atatcaagaa aaaaatgcct ttgttacagt tacgcaaaaa agatttcaaa
     5041 tttgaaaaag aagagtttgc tgtacaccta aatgctgctt tgccaatggc gtttcaatct
     5101 tcgatcatcg ctgttggtgc tatcgtgtta caagcagcac taaatagtct agggacagat
     5161 gtcgtagctg ctcaagccgc tgctggtcgt atcgaccaat ttgcaaatca gccgatgatg
     5221 tcatttggta ttgcaatggc aactttcact gcacaaaact atggtgcgaa agaatatggc
     5281 cgaatcttgc aaggggtacg tcaaacttta ctgatgagtg tcggatttag tctcttagca
     5341 ggtgctatcg tcattttctt cggtcatttc tttgttcaat tgtttgttag cccatcagaa
     5401 acacgtgtat ttgaattagc acaaacctac ttcaatatca atgggtctct ttactggatc
     5461 ttagcagtcc tgttcatttt acgctacaca cttcaagggc ttggacaaag caagatccct
     5521 acgatcgccg gtatgatgga attgcttatg cgttcttttg cagctatcgt tcttacagga
     5581 atgtggggat acccaggagc agcagcagct tctcctttag cttggatcgg ttctgttgcc
     5641 gtgttgcttt actcttatat gcgttcgatg aaacaattga aacacatggg tgaagaggaa
     5701 catttcacat tagaacatgc agaagcaaga tagccttgat taaaagaaat cgttgcggct
     5761 aaaaatgaaa acttttattg aaaatatctt cttcgtttac cgaaaacagg ttttttagat
     5821 aacaaaaagg ctgtgacaaa aaatgtcaca gccttttttc ttttattctg tttttctttc
     5881 cgtggactct actttgaaat aatcgatatg tgcatgctgg tattctaata ccgtgaaacg
     5941 gaatgatgca atctcaatga ttgttcctgc ttttatttct ttatatcggc tagaagcaaa
     6001 gcccgcaagt gtagtaaaat tcgtttcttc aaactctgga atctctacat gaaaataacg
     6061 ctggaaatca tctaatgtta gtttgccgga gatgatataa gagccatctg actgttccgc
     6121 tatcaatgct tcgtccaaat ctgtctcatc tcggatttcc ccgacgattt cttctaaaat
     6181 atcttcaatc gtcactaagc cgcttgtccc tccgtattca tcttttaaga tagcaatatg
     6241 cttacccttt tttcgcatga tcgtcaataa tttttttata gggatcgttt cagttgttac
     6301 gatcggctct tcaatcaact gttctactgt cagctggtca tctttataag attgcttgat
     6361 caaatctggc aaggtgacat aacctaaaac attgtctttt gattctaaga taaccggata
     6421 gcgagtatgt ccttgttcaa tcgaagcttt tatcgcttct ttgacggttt ctgaagcttc
     6481 gaatacttgc atggacgtac ggtctacttg tatatctttt gccaaggtat catcaaattc
     6541 aaacacgttt tccaaataat aatattcttc tttggtcaac tctccttttt cataagaatt
     6601 caatgcgact aatgtcagct cttcttgaga caatgtctct tctccttcag atacgagacg
     6661 cacacctaat agcttcccta gccctgcagc tgaatgattc aatacccaaa taaaaggaaa
     6721 cattacttta taaaaataat gaagtggttt aactacgaac aagacgacct tctccgtatt
     6781 gacgatacta tagctcttag gaagcagttc gccaataacc acatcgatat acgtaactaa
     6841 aataaatccc agcgccacag agattgtact gctaatagcc gaactaaaag gtagtttacc
     6901 gatcactggt tctagtaaag ccgcgacaga tccttcaccg acccacccga tgatcaaacc
     6961 ggttagcgta attcctaatt gactagctga taaatagtta tctaaatggt gtgtaacatg
     7021 aagagctagc ttggcgttct ttacattttc cttttctagt tgttccaatc ttgatcgtct
     7081 gattttcact aaagcaaatt cacttgctac aaaaaatgaa gtaattgcaa tcatcaaaaa
     7141 taaaataatg aaattgataa ccatattctc ccgcctttct ctttttctat tgtacccttt
     7201 ttctacaaaa agattgaaaa taatgcgtat tcatatttag gaataaaaaa ggagatgcgg
     7261 catttttcag ccacatctcc ttatcacttc aaaatcattg cgttacttgt tgctaaacag
     7321 ctttttcatg acctctgata aaaacggtat tcaaaagctt gcatctacgg cattaagccc
     7381 aaacagatga aaaacatgag aagctgtttt tatctgctcg ttcttactgc ttgttgcagt
     7441 acagcttttt catgacctct gataaacggt gttcaagtag ctgacattcg acattagttc
     7501 aggtcaaagc gctactttca caaccgctct ttcaaccatg ttttccgagt atttccaatg
     7561 ataagcggaa cagtttcatg ttttacttcg ctgtactcta gcccaaacca tgtttctggc
     7621 gaggtagcga tttttttgat tgccagtttt gcctgcatga tttgacgttg ccattttcct
     7681 agagttgtca cattggaaac tacttcatca atcaggacaa attggaaatc gccaacttct
     7741 cgccctggtg tcagagagta tctttgtggc tgttttggca aacggccttg tttcatcaaa
     7801 tcatggatga cttggcgaac atatacgttg atttcctgtt ggaccctgaa acctaagaac
     7861 agattcactt ggacaataaa atcagtgtcc atcatatcta cttgatattc tttcgtatat
     7921 ggctcatccg tcacttccac atgaacaaac caatagactc gtgctctttt aggccgttta
     7981 tctaaaatcg aatagatgaa ctgtcggcca actttatctt cagccatatc aggaaccaag
     8041 aagaccacat ttgtctgata gattggtaaa gaagtatcat cacgtaattc tctaagctgc
     8101 gggatataat ctctcaaaga cacatcctcg gttgacgatt cgcgaataat gttcccttgt
     8161 tcccaaataa acatcacgac taagatgatc aaaccaatca gaacggctac aaaaccgcct
     8221 cggaagaatt tgacaacact tgagataaag aaaacgactt ctatcgcacc gaagaaaaag
     8281 gtaactaaat atgcaagcca acgagaatgc ccattttgga taagataaaa gtaaagcagt
     8341 gctgttgtca tcaacatcgt cacagtgatc gatagaccgt aagcagcttc catatgatga
     8401 gacgttcgga atgtgacaac cactagagaa caggcgatcc ataaaatcag attgactgct
     8461 gggatataca tttgcccgat actgttccca ggatacatga tctttaaccg aggcagcagt
     8521 ttcaacttga ttgcttctga aactagcgta aacgaacctg taatcaatgc ttgcgaagca
     8581 atgactgcag cgactgttgc aaaagcaacg ccgatcacga tccaactttg aggcatcatt
     8641 tggaagaatg gattcaggtt cttgatttgc tgtgcttcag ggttttgata aacattcaac
     8701 aaccacgcag cctgcccaaa ataattgata accaaacaaa ttttgacgta aggccagctc
     8761 agacgaatat ttcgtttgcc gacatgtcca agatcggaat aaagcgcctc tgcacctgtc
     8821 gtagccagga aaatatttcc aagaatgaac aagcctaatt tgttatctgc actaaaaagc
     8881 agctggatag cataataagg attcagtgca cggataactg tccagtcttg actgaagttc
     8941 attaatccca ttacgcctaa aaaagtaaac caagcgaaca tgattggtcc gaatgctttt
     9001 ccgacaatat ctgtaccaaa gcgttggacc atgaataaaa caaaaataat aactaaagtg
     9061 ataatgacga tcacgttctg gttattaccg aaccggtcaa aaaactgcgg aattcctcgc
     9121 aagccttcaa tcgcagtcgt taccgtcaca gcaggggtca ataccccatc tgctagtaag
     9181 gcagctcctc cgatcattgc aggaatgatc aaatatttcc caccttttcg gacaagtgtg
     9241 tagagtgaga aaattccacc ttcaccatgg ttatctgcat tcaatgcaat cacgacatat
     9301 ttgattgttg tcagtagagt caatgtccaa aaaatcaatg agactgatcc gataacaaaa
     9361 tcaggattga ttcctgacaa tccgccatta tcttcaacaa tcgatttcat aacgtaaagc
     9421 ggacttgtcc cgatgtctcc gtagacgact cccatcgcta caagcaggcc agtcattgat
     9481 atctttttgg tattgtgcgt tgttgccacg tttttccctc atttcttgtt atatggatat
     9541 cctttaggta agcttgaatg atagatgata ttcttatcca tgacacccgc tttcctaaat
     9601 tgcttctaat tatccaagta acacactgaa gtgtcaactt atttgaataa aattattctt
     9661 tctttggacg ttctctgata cgtcttgcca caaatgaata aagagcaagg caaaaaattg
     9721 cacccaataa tgctggtatc aaataaaaac cgccgagttc cggtcccagt ggtcctagta
     9781 aaaattcgcc gagccaacta cctaaaaaac cgataatgat atttccagat acgcctcccg
     9841 ggacttcctt tcctaaaatt gcgccagcta tcaaacctaa tataccgccg ataaataacg
     9901 accataaaaa attcagcatc tcctttccct cctttatcca tatttctcac ttttatttta
     9961 cgctttattc agaaggactc caaaaatatg cgccaagaaa ctccagaaaa aaagaagttg
    10021 taacaaaagt gttcagctta tttccgtaga agctgcttct ggaacaccgt gaatcagagg
    10081 ttgtgaaatc agcggtttga cctgagtatt agagaaacaa acggaaaaat agttcctcat
    10141 attttgccgt tttttgagct aatatcgagg gacagctgat tgaacatcgt ttattggaga
    10201 ggttgtaaaa aagctgttct gcatcaagta ataagaacag ccaaataaaa acagctccta
    10261 atgtttttaa cttggctgga cttattaccg cagatgcaag cttttgaaca ccgtttattc
    10321 gaaaaaaaag gactgtgaca cggcttttgt cacagtcccc ttttttcgaa taattattgt
    10381 ccccctgtca ccttcacgat cacaagtaca ttattcctat gaattaaatt atttttcttc
    10441 atttttcgtt gaaccatctt cgttcaacat tgcttttctt gacagattta cgcgtccttg
    10501 tttatcgatt tcagttactt tcacaaggat ctcatcacct agtttaacaa catcttcgac
    10561 tttattgaca cgatcgtttg ctaattggga aatatggaca agtccatctt ttcctttgat
    10621 caagttgacg aatgcaccga atttttcgat acggacaact ttccctagat aaacttcacc
    10681 aactttgact tctttggtca aatcttcgat gatcttgata gcttttttga tcatttctgc
    10741 atcagctgaa gcaatactta cttttccatc ttgatcgata tcgattttca caccagtttc
    10801 atcgatgatt ccgttgatcg tatcgccgcc tttaccgata acatctttga ttttagcagg
    10861 ttcgatctgg atcatttcga tttttggtgc atattggctt aattcttcac gtggagcagc
    10921 aatcgttgaa gtcaattctt ctaagatttc catacgtgct tgttttgctt gagttaatgc
    10981 ttcagttagg atttgttctg tgattccttg aatcttgata tccatctgta aagcagtgat
    11041 accatctttt gtaccggcaa ctttaaagtc catatcgcca agatgatctt ccagcccttg
    11101 gatatcagtt aggatcgtat agttttcacc atcagaaaca agtcccatcg caataccggc
    11161 gactggcgct ttgattggta cacctgcatc catcaatgct aatgtgccag cacagatact
    11221 tgcttgggaa gaagaaccat ttgattccaa tacttctgct actaaacgga tcgtataagg
    11281 aaattcttct tctgaaggga ttacttgtgc taacgcacgt tcacctaatg cgccatgtcc
    11341 gatttcccga cgccctggag agcctgcacg tcctgtagaa ccaacagaaa attgagggaa
    11401 attgtagtgg tggatgaatc gtttgctgac ttccacccct aaaccatcaa tgatttggtg
    11461 ctctcctaga ggtgcgagtg tacaagctga taaagcttgt gtttgtcctc gtgtgaacaa
    11521 acctgatcca tgtacacgtg gcaataagct gacctctgat gacaatggac ggatttcatc
    11581 caatttacgc ccgtcaggac ggatcttatc gatggtgatc aattcacgta cgacatcttt
    11641 ttcaagatct tctgtgattt gtttaacttc tttcaacaag tgatcttcat cttcatgacc
    11701 tgcaaatttc tcagcataag cttcgcggat atcgatcttc acctgctcga tattatcttc
    11761 gcgagcaagt ttttcttcag tcattactgc tgctttcatt gtagcgtaag aagcatcaaa
    11821 gatttctttt ttcaatactt catcaacttg cagtaaagtc acttccattt tttctttccc
    11881 tactgcttga acgatttctt cttggaaagc aactaactct ttgatagcgt caaaaccaaa
    11941 cagcaatgca ccaagcatgt cttcttctga aacttctttc gcgccgcttt caaccatatt
    12001 gatggcttgt ttcgttccgg caacagtcaa ttcgatatct gtttgttctg cttgttctac
    12061 tgttggattc aagacgtact cgccatttac acgaccaact tctacgcctg cgattgggcc
    12121 gtcaaatggg atatctgaga ttgatagtgc taaagaagaa cctagcattg ctgccatagc
    12181 tggcgagcag tctgtttcta cactcatcac gatgttcgtt acttggactt cattacggaa
    12241 gccttctgca aacatcgggc gaattggacg gtcgatcaaa cgggcagtca atgttgcttc
    12301 cgtacttgga cggccttctc gtttgatgaa acctccaggg attttccctg ctgcatacat
    12361 tttttcttca taattgatcg ttaatgggaa aaagtctgta tcttttgctt ctttagaggc
    12421 cacagctgca cttaagacta ctgtatctcc ataacggact aaaacggctc cgtttgcttg
    12481 ttttgctagc tgaccgactt cgatttgtaa gggacggccg ccccatgtcg ttttgaatac
    12541 ttgtttttct gacataactt ctccttttcc ttctcgtgaa agcaagacgc tactaaacaa
    12601 atgaaaactg ccgaaagccg tcttttgagc agctttcatt tggttagtag gagtccatct
    12661 agcttgatca cggaatttta cttaattgat atacgagtaa aaaaagtgag attcatgtga
    12721 atcccactct ttttgactaa aattaacgac gcaagcctaa acgtttgatc aattcgcggt
    12781 aacgttgaac gtcagtttta cgtaagtaag ctaacaagtt acggcggtga ccaacttttt
    12841 tcattaggcc gcggtatgaa tgatggtctt ttttgtgcac gcgtgcatgt tcattcaagt
    12901 ggttgatttc ttcagttaat acagcgattt gtacttctgg agaaccagta tccccttcat
    12961 ggcgagcgta ttcgttgatg atttcattct tgcgttcttt tgaaattgcc atttctttca
    13021 cctctttcga ttattcccct gcgactgagt aaaacgttgg tgattcgctt aaccaagtgg
    13081 caggtcatgt gcctagagca cacagctata ctttacctga aaccgggttg aaaatcaagt
    13141 agttaatcat taagaaaagg tagttttcaa acaatcttac tactactttt ccatttttgt
    13201 ggtaaactat aatgcgaaaa tagacttgaa acacagtctt ttaagaaagg ggtacatatt
    13261 ccatgattac aatggatgat atcattcgtg aaggaaatcc gaccttacgc gaagttgcaa
    13321 aagaagtttc tcttccatta agcgaagaag atatctcttt aggaaaagag atgcttgagt
    13381 tcttaaaaaa cagccaagat ccaatcaaag ctgaagaact acacttacga ggcggtgttg
    13441 gcttagctgc tcctcaatta gatatttcta aaagaatcat tgctgttcac gtaccaagtc
    13501 ctgacccaga ggcagatgga ccttctctaa gtactgttat gtataatcct aaaattttga
    13561 gccattctgt tcaagatgct tgtttagggg aaggtgaagg ctgtttatct gttgatcgag
    13621 aagtaccagg atatgttgtt cgccatgcca aaatcactgt gtcttattat gatatgaatg
    13681 gtgaaaaaca caagattcgt ttgaagaatt atgaatcgat cgtcgttcaa catgaaatcg
    13741 accatatcaa cggtgtgatg ttctatgacc acatcaacga tcaaaatcca tttgcactaa
    13801 aagaaggcgt attggtgatc gagtagagaa ttggcaggtt ccttcgatac tatgctacaa
    13861 gaaagcttta taaaaaaggg gagtgctcaa aagctgcact tccctttttt atgtttctcc
    13921 actaatcgaa atttagatag acatctagaa atcgcaattc caaaaaattc tgtgtattgg
    13981 atacgcatct tttcttattt tttcttattt cttccatatg ggtgtttatc tcagagatga
    14041 tagaatagtt tctaggataa aaagtagcag ctacgatgtt atccttcgta gaggattcct
    14101 gcttcagcta gtttttgttt gatgtttttc agcatatgct tttctgggta gcggatcgta
    14161 tgcagatgga tgccgcctgt taattcggat aacaaagtag cattactttt ttgataacgt
    14221 ctcataaagg aatcgatatc ttgtggcgtt ttgatgtgca aagttcctgc taactcaccg
    14281 taaaggggat gttccacaat tacatcaatg atttcaccac cattttcaac gattagtctc
    14341 agttcttctt ctgtttgatc ttttccatgc tggacagcga ttttactgat gtgcccagta
    14401 ttggtttctt ctgtttcgag gatataacct cttgctgttg ccacgatact tttacctgca
    14461 gctcgtagta aagcaatatc gcctacaatg atctgacggc tgactccaaa agttttcgca
    14521 aacttgctag cactcactgg tttttctgta tttgccaagg tttgcatgat ttgttttcgc
    14581 cgtgtctctc cttcgatcac acttattcct ccttcatttt gttttggtat tcgcgcgagt
    14641 gtttcatcaa atcaacatac gtatctgtta ttgtttcctt atatccctta tttttcagca
    14701 gactaacaac tttatccaat acttgctgct ctctttttgc atcataaact gcttggtttt
    14761 cttctttttt cacttgtcct attttagtta ccgtatccat tcttttttct aataaagcaa
    14821 tcaactctcg atcgatcata tcgatcttat gacgtaatgt ttcaagagac tcttctgtta
    14881 gttcttcctc tactgtcttg atgatacgag caggatttcc tgcaatcact acattgtcgg
    14941 gaaaagattt ggtcacaacc gaacctgcgc cgactactac gttgtcccct agagtgacac
    15001 ccggcgtgac gataactcct ccgcctaacc aaacattatt accgatttta atgggttttg
    15061 cgtactccag accgctgtta cgtttcactg gatgtagtgg atgcgtcgcc gtgtaaagct
    15121 ggacattcgg agcgaacatg cagttatcac cgatttcaat cgtgctgaca tctaaaaatg
    15181 tacaattgaa atttgcataa aaattctccc caacaaatat attatatccg taatcaaaat
    15241 tgataactgg ctccatatag atttttttcc ctgtacggcc aaaagtctct ttcaacaatt
    15301 gggatcgcag ttccgctgat tctgcttggt tgatgatttg gctttgactt cttgcaaaca
    15361 tacggtcggc aaccagctca ggatcattgg caaaataaag ctcgcctgca atcatttttt
    15421 ctttttcggt tttgaattca gtcataatct gctcctaatt cttgtatttt tttgaaaaca
    15481 accgctccgt cttcttgaat aaacgtataa ggctccgcta aataaacagg cgtttgattg
    15541 attactaaga ttttggctga cggctggcga aactgtacca gatcacaaaa cggatgaact
    15601 tgaaaactcg ttccaacaat gacgatcagc tctgcttggc tgacggcata agccgcctgc
    15661 tccatgactc catcttgaaa cccttcacca tataacacga tgtctgggcg tatttgtcct
    15721 ccgcatgctt gatgtttgtc gctgtgaaga tattctttcc agtctaccgt ttgttgacat
    15781 tttcgacaat gacattgata caaacttcca tgaaaattga cgagttgcgg gcttttagcc
    15841 tttgcgtgca aaccgtcgat gttttgggaa acaacccaaa catttttttc tttcgctaga
    15901 tgtgccattt ccaaatgaat gatattgggt tttgcttcag gatgataaat ctttttgaca
    15961 aattgataga atttatccgg ttcattcacc attgcttgat gactcagcaa gtattccggc
    16021 tgctccatcc cgtggtagat tcctgacaaa gatcgatagt ctggcactcc agaaggtgtg
    16081 gatacccctg caccggtcaa aaatgtaatt tgctgataag ctaatatctc ttttgctgct
    16141 tcgtctactg ttaattgttt catgttttgt cacctcactt tccattatag cccatactcg
    16201 aacaaattta ttgttgaaaa gtcagaaaaa tgggaataaa aaagtgttat gggcatttga
    16261 acaatttatc acaatgttca ctgacaaaag aatgaaaacg tgttacaata ctgctgtata
    16321 aaagtgaggt gaatcgatat gttaccattc tttatttatt ggggcgttat tctggcttgt
    16381 atcgcctggt tagcgttaag cgtttatttc tctgtttttt atcttgtacg caaagaaaat
    16441 ggaaatcttt gggcttttgc tttattcaac gtgattgccg caattgtttt agccattaca
    16501 ttagccgtat atcgaacatg gggctgggga atcacccaat actcaagttt gatttatcta
    16561 atattagcca tttatggcgt cgttgttctt ttgcaagcga tcctaggacg tgagccaaag
    16621 aaagcggcag cttaaatgat cgagatggaa ctggacacag gaaattttct gttctagttc
    16681 tttttttatt gtattacata catttttgtg tataattata ctatcgtttg caatggatag
    16741 atgattcaca ttttgattgt tttttcggta aaagtaaaga tttctatatt tatcagtatt
    16801 ttttcaaaaa acagcagtta tagattgaca aagcctctcg agtatcgtaa actttttttg
    16861 tataaataac tgaatacgag atgcctcaat caatgaggta gaggtcgcga gaatcattaa
    16921 ccctgtggag tgaagcaaac atggagaagc aggaataggg aggatcgccg aaatgtgcac
    16981 ttttttgctt ggagtgtatg ttgggacgca agttaagagc ttgcggactg tcttagcagt
    17041 gatgctaagt tgcgctatgt tttgtgagag gtttatcacc ttatggaatt ttagcggcct
    17101 ttttatatct ataaatcggt cgctttttat tttttcagat aaagctttac cgcatttcat
    17161 ctagaccgct cgtgtatcat ataatcagaa agggagaaaa aaatgaaaaa aaatatggtt
    17221 tcagttgccg tactatttgc ttttgtcttc tcactattca gtgtgggatc tctggcaaat
    17281 gcagatgaaa aaacaccgag cgatgagttt cgcgtaggta tggaggctgg gtatgcaccc
    17341 ttcaactggt ctcaacaaac agatgagaat aatgccttgc caattcaagg ccaaaatagt
    17401 tacgccggcg gttatgatgt tcaaatcgct aaaaaagtag cagatggttt agggaaaaaa
    17461 ttagtcatcg tccaaacgaa atgggatggt ctggctcctg cccttcaatc aggcaagatc
    17521 gacgcgatca tcgccggaat gagccctact gctgaacgac gaaaagaaat tgattttacc
    17581 gatccttatt acgaatcaca attagtagta gtagttcaaa aagatagcaa atatgcaaaa
    17641 gcaaaaagtt tagcagatct ttctggagca aagattactg ctcagttaaa tacattccac
    17701 tatactgtga tcgatcagat accagatgtg cagaaacaac aagcaatgga taatttctca
    17761 gcaatgagaa cagctttagc ttctggaatg atcgatggtt atgtcagcga acgtccggaa
    17821 ggtgtaacgg caactagtgt gaacaaagac ttggaaatgc ttgaattcag cggtgcagat
    17881 ggcttccaga caaacccgga agatgttcag atttctgttg gtatgcgtaa aggcgacccg
    17941 gatatccaaa aagtaaacca gattctttct ggcatctcta acgatgaacg aaccaaaatt
    18001 atggaccaag cagtcaaaga tcagcctgct gcaactgata gtgaagaaaa acctggcatc
    18061 atttctgatt tcactacgat ttggaaacaa tacggcaata tgttcttacg aggtgctgga
    18121 cttaccttgt tcatcgcatt gatcgggaca gttgtcggta ctacacttgg attactgatt
    18181 ggtgtcttcc gttcggtacc tgaatcagga aatgcactga ctcgcttctt ccaaaaaatc
    18241 ggaaatgcac ttctttctat ctatgtcgaa gtattccgcg gaacaccgat gatggtacaa
    18301 gcaatggtca tcttctacgg tctggcactc gcttttggca tttcattgaa ccgaacgatt
    18361 gccgctttgt ttattgtctc tctcaatact ggagcttaca tgacagagat cgttcgtggg
    18421 gggatttttg cagtagatga agggcagttc gaagctgcgc aagccattgg tatgacccat
    18481 ggccaaacga tgagaaaagt tgttattcca caagttttac ggaatatctt gccagcaaca
    18541 ggaaatgagt ttgttatcaa tatcaaagat acagcagttt taagtgtaat cggcgtagct
    18601 gatttgttct tccaaggaaa ctctgcttcc ggtgcgaatt tccaattctt ccaaacattt
    18661 acgatcgtcg ggatcatcta cttagtcatg acctttacga tcaccagaat cctgcgggcg
    18721 gtagaaaaga aaatcgatgg tccttcagct tataccaagc ttgaagaaat cgacaattca
    18781 aatttgcagg aataaggagg aagaatcatg aatgaaaaaa ttattgaaat caaacatcta
    18841 agaaaaagct tcggtgaaaa tgaagtattg aaagatatca gcgtaacagt caataaaggt
    18901 gaagttgtga cgatcatcgg ttcttccggt tctggtaaat ctactttctt gcgctgtatc
    18961 aatttactgg aaaaaccaac aggcggcgag atcatttata atggagaaaa tgtattagct
    19021 cctaaatata atttacctaa atatcgaacg aatctaggta tggttttcca atccttcaac
    19081 ctgttcaaca atatgaatgt cttggaaaac tgtatgtctg gtcaaacaac tgtcctgaaa
    19141 cgagataaag aaactgccaa aaaagtagca atcgaaaatc tggaaaaagt tggtatggat
    19201 cgttatatcg aagccaaacc agcacaatta tctggtggac agaaacagcg tgtcgcaatt
    19261 gctcgggcat tatcaatgaa tccagatgta ttgctattcg acgaacctac ttcggcgtta
    19321 gaccctgaaa tggttggcga agtgcttaat acgatcaaag acttagcaca tactggcttg
    19381 acaatgctta tcgtgacgca tgagatggaa tttgcaaaag atgtatctga ccgtgtcatt
    19441 tttatggata aaggtgtgat tgcagaagaa ggtacaccag aagatatctt tgtccatccg
    19501 aaagaagaac gtacaaaaga attcctttca cgtattttaa atgcttagga tcaatagctg
    19561 attgggacaa agagctgcgg tgtttaccgc agttcttttt tatgaattac tcataaaagg
    19621 taaatttctg aaaattttgg aatcttagtt gtgtttttca gaaaactctt ttaatatgga
    19681 agtaattaaa cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc
    19741 gtggactgaa aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt
    19801 tgtttttagg ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc
    19861 ttattactgg atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa
    19921 acaccaataa ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt
    19981 tcatcactgg ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag
    20041 ccatcggaat gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga
    20101 ttgcattagg tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag
    20161 agttttggtt tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt
    20221 atatgatcct cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt
    20281 ctcatggcgg attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa
    20341 cctttgcttt tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg
    20401 aaaaagtgtt gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag
    20461 gatctctttt tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc
    20521 catttgtaga agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag
    20581 tcgtattaag tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc
    20641 ttcgttcttt agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc
    20701 atgtgccagg gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga
    20761 attacgtgat gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct
    20821 tgtttatctg gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca
    20881 aaaaagctca ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt
    20941 acatggcctt tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac
    21001 taacacctgt gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga
    21061 agtaagaaag tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa
    21121 aattgcttct taaatttttg tgaaatttcg gcttatttct tggagttaaa agcttctgtc
    21181 ccagcctctt ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata
    21241 ggaaaaaatc caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa
    21301 aaagacaccg gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt
    21361 tgacaaaact ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa
    21421 gataccaaaa gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa
    21481 agcttcaggg ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag
    21541 caaaaagata ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg
    21601 atgatggttc acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt
    21661 atttcggatg acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac
    21721 aagaactctc aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt
    21781 cacgatgatt cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata
    21841 accgtcgttt tatataggaa attttctgaa aattgttgca tatttttcga aattttgtta
    21901 cttttaaaaa aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc
    21961 tttttatagg ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg
    22021 ttcatttggg tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta
    22081 ccggtatcgg tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg
    22141 tatatgaatt agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt
    22201 acttagttat cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg
    22261 gtttagcacc atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg
    22321 tattttttgt gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg
    22381 gaaagttcct gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt
    22441 tgaatccact aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt
    22501 ttttcacagg gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg
    22561 ggatcatcat tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta
    22621 aagacacgat caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc
    22681 tcgcttattt aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca
    22741 cgctggctca gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta
    22801 tcgttatatt agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat
    22861 tcacagattt gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc
    22921 cttgtttagc ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga
    22981 tgttcatcta tccattagca atgacactga ttttactagt gttagttggt cctttgttta
    23041 agcagcgtac ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg
    23101 atgggttgaa cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat
    23161 atgttgcgga aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag
    23221 ttatcggttt tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt
    23281 gataaaagag gttgtgaaag agacgttcag ccttattgcc gataggctgt ctcttgaaca
    23341 ctgtttattg agaggtcgtg aaaaagccgc tcagtttcga gtattaagaa atattttttg
    23401 aaaatggctt ctcacatttt tgcataaatt tgacttaata ccgagaaact ggcttttgaa
    23461 caccgtttat tgagcgtcta taaactgacc tgagtattag agaaacaaaa cggcaaagta
    23521 gctccatata ctttgccgtt ttgttttgaa ctaataccga agagaagctg atcaaacaac
    23581 atttctttta taatatagat tttagacata tatatgatat aaaaatagtt ttcgcaaaaa
    23641 aa
//
LOCUS       DAZKCH010000040        23595 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000040 DAZKCH010000000
VERSION     DAZKCH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.040"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            68..886
                     /gene="purR"
                     /locus_tag="ACG84X_001590"
     CDS             68..886
                     /gene="purR"
                     /locus_tag="ACG84X_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFP9127462.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            1389..2762
                     /gene="glmU"
                     /locus_tag="ACG84X_001591"
     CDS             1389..2762
                     /gene="glmU"
                     /locus_tag="ACG84X_001591"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFP9127463.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            2856..3827
                     /locus_tag="ACG84X_001592"
     CDS             2856..3827
                     /locus_tag="ACG84X_001592"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFP9127464.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      3833..3935
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4001..4570
                     /gene="thiT"
                     /locus_tag="ACG84X_001593"
     CDS             4001..4570
                     /gene="thiT"
                     /locus_tag="ACG84X_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFP9127465.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(4651..5424)
                     /locus_tag="ACG84X_001594"
     CDS             complement(4651..5424)
                     /locus_tag="ACG84X_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127466.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            5691..7391
                     /locus_tag="ACG84X_001595"
     CDS             5691..7391
                     /locus_tag="ACG84X_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFP9127467.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            7361..7579
                     /locus_tag="ACG84X_001596"
     CDS             7361..7579
                     /locus_tag="ACG84X_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFP9127468.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            7599..8489
                     /locus_tag="ACG84X_001597"
     CDS             7599..8489
                     /locus_tag="ACG84X_001597"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFP9127469.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            8507..8791
                     /locus_tag="ACG84X_001598"
     CDS             8507..8791
                     /locus_tag="ACG84X_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127470.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            9278..9892
                     /gene="gmk"
                     /locus_tag="ACG84X_001599"
     CDS             9278..9892
                     /gene="gmk"
                     /locus_tag="ACG84X_001599"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFP9127471.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            9897..10202
                     /gene="rpoZ"
                     /locus_tag="ACG84X_001600"
     CDS             9897..10202
                     /gene="rpoZ"
                     /locus_tag="ACG84X_001600"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFP9127472.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            10455..12863
                     /gene="priA"
                     /locus_tag="ACG84X_001601"
     CDS             10455..12863
                     /gene="priA"
                     /locus_tag="ACG84X_001601"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFP9127473.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            12878..13369
                     /gene="def"
                     /locus_tag="ACG84X_001602"
     CDS             12878..13369
                     /gene="def"
                     /locus_tag="ACG84X_001602"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFP9127474.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            13362..14300
                     /gene="fmt"
                     /locus_tag="ACG84X_001603"
     CDS             13362..14300
                     /gene="fmt"
                     /locus_tag="ACG84X_001603"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFP9127475.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            14300..15658
                     /gene="rsmB"
                     /locus_tag="ACG84X_001604"
     CDS             14300..15658
                     /gene="rsmB"
                     /locus_tag="ACG84X_001604"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFP9127476.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            15671..16411
                     /locus_tag="ACG84X_001605"
     CDS             15671..16411
                     /locus_tag="ACG84X_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFP9127477.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            16408..18477
                     /gene="pknB"
                     /locus_tag="ACG84X_001606"
     CDS             16408..18477
                     /gene="pknB"
                     /locus_tag="ACG84X_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFP9127478.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            18642..19541
                     /gene="rsgA"
                     /locus_tag="ACG84X_001607"
     CDS             18642..19541
                     /gene="rsgA"
                     /locus_tag="ACG84X_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFP9127479.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            19554..20204
                     /gene="rpe"
                     /locus_tag="ACG84X_001608"
     CDS             19554..20204
                     /gene="rpe"
                     /locus_tag="ACG84X_001608"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFP9127480.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            20205..20843
                     /locus_tag="ACG84X_001609"
     CDS             20205..20843
                     /locus_tag="ACG84X_001609"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFP9127481.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            20998..21852
                     /gene="mreC"
                     /locus_tag="ACG84X_001610"
     CDS             20998..21852
                     /gene="mreC"
                     /locus_tag="ACG84X_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFP9127482.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            21856..22365
                     /gene="mreD"
                     /locus_tag="ACG84X_001611"
     CDS             21856..22365
                     /gene="mreD"
                     /locus_tag="ACG84X_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFP9127483.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            22620..>23595
                     /locus_tag="ACG84X_001612"
     CDS             22620..>23595
                     /locus_tag="ACG84X_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFP9127484.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTT"
BASE COUNT         7943 a         4250 c         5070 g         6332 t
ORIGIN      
        1 ctcgaatttt tgaagaaaaa cttatataat gtaaaacgat aaaatttctt aaaaggagtt
       61 ggaataggtg aaagtacgtc gcagtgaacg tctagttgac atgacacagt atttattgaa
      121 tcacccgcat gaattgattt ccttaacaag ctttgccgaa cgttatgaat ctgctaaatc
      181 ttctatcagt gaagatttgg gaatcatcaa gaaaacattt aaagaacgag ggtatggaac
      241 cttggaaaca atcccgggtg ctgcaggtgg tgtattgttc atccctgaaa tttcatatga
      301 agaggcgaaa aaatatattg aatctctagc agaacgtcta tcagaacaag accgtctgct
      361 tccaggagga tatgtttatc tctctgattt gttaggagaa cctgaactgc tgcgtcaagt
      421 tggaagaatc attgcttcta aataccttgg tgaaaaaatc gatgctgtaa tgactgtagc
      481 cacaaaaggc gtacctattg cccaagctgt gtcctattat ctgaatgcgc cattcgttat
      541 tgtacgccgg gactcaaaaa taacagaagg atcaacagta agtgtcaact atgtgtctgg
      601 atcttctgaa agaattgaaa agatggaact gtctaagaga agtttgaaac gtggttcacg
      661 tgtccttgta gtggatgatt tcatgaaagg cggcggaaca gtcaacggaa tgaagagctt
      721 gattgaagaa ttcgaatcag aacttgttgg catcactgta tttgccgaat caaaattcaa
      781 cggtcatcgc gccatcgatg attatacgtc actgctttat gtcaaagatg tagatactca
      841 aacgaaaaat attacggttg tgccaggaaa ttatttttca gaataagagg ttgtgaaaaa
      901 gccgcttagt ttcgagtagt aagaaaaatt ttgtgaaaat ggctttccac attttttcat
      961 aaatttggct taataccgag aaactggctt ttgaacaccg tttatctaga ggttgtgaaa
     1021 tcagcgtcct gtcctgagta ttagctcaat aaacggaaaa attgctcctc atattttgcc
     1081 gtttattgag ctaataccga aggtcagctg attgaaaaac gtttaatgaa gaggttgtaa
     1141 gcctaccgtt taactctaag tcacaagaaa cgatttcaaa aaacagcttt tcatgtttta
     1201 tgagtagtgt gacttgtgac cgaggagttg gcaggagagc accggttacc aaatagatag
     1261 gcccgttatg gtctatctat ttttttatcc agaaaacgct gggataaaag aaaatcactt
     1321 gttttgttga aaaaatgggt atactgggat aaactgaaat cagcaaacta tatttaggag
     1381 tgacgcagtt ggacgcacgt tatgcaatta ttttggcggc agggaaaggt acccgcatga
     1441 agtcaaaatt atataaagtt ttacatcccg tttctggtaa acctatggta gaacatatca
     1501 ttaatcgggt cagtgaaacg aaaccagatg aagtgattac gatcgttgga cacggagcag
     1561 aacaagttaa agcacaacta ggagaacgca gtaaatatgc gttacaagca gaacaattgg
     1621 gaacaggaca tgctgttttg caagctgctt ctttcttgga aggaaaaaaa ggaacaacgt
     1681 tagttatcag tggcgataca ccattattga ctactgaaac gctgaacaat ctttttgaat
     1741 atcaccaagg aaaaaatgca agtgcaacga tcttgacggc acaagcagaa aacccaacag
     1801 gatatggacg aatcatccgt gaccatattg ggatcgtaga aaaaatcgtg gaacaaaaag
     1861 atgcaacacc agaagaagct cttgtacaag aaatcaatac aggaacttac tgttttgaca
     1921 acgaagcttt gttcgatgcg ttaagcaaag ttggaacaaa caatgctcaa ggtgaatact
     1981 atctaacaga tatcatcgaa atcttaaaag aagaaggcca tacagttgct gcttatcaaa
     2041 cggatgattt tgaagaatca atgggagtca atgatcggat cgcgttagct aaagcaaatg
     2101 agatcatgag aaagcgaatt aaccagatgc atatggtcaa tggcgtaagc tttgtcgatt
     2161 cagcaacgac atacatcgat gcaggcgtag aaatcggtcc agacacattg atcgaagcag
     2221 gtgtacaaat ccaaggaaat acagtcattg gttctgattg tgtcatcggg tcacattcaa
     2281 aaatcgtaga cagtaggatt gaggatcacg tcgtcattga aaactcagtc attgaaagca
     2341 gccatgtcaa gaaacatgca gatgtgggac cttatgcaca tttacgacca aaagctgaaa
     2401 ttggcgaaaa cgtccatatc ggaaactttg tggaagtgaa aaatgctcaa atcggcaaag
     2461 gaactaaagt cggtcacttg acttatgttg gtgatgctac gctgggagaa gaaatcaatg
     2521 tcggatgtgg tgttgtcttc gtcaactatg atggaaagaa caaacatcat acgactgtcg
     2581 gcgaccacag ctttattggt tctagcacga atatcatcgg acctgtcgag gtagctaaaa
     2641 acagttcgat tgctgccggg tcaacaatta cagacaatat tccagaatat gcgctggcaa
     2701 ttgcgagagc aagacaagtc aataaagaag gatatgcaaa aaaactccct tatctaaact
     2761 aagacttttg caaaatcact tgatttattt aaaaaatatg actactattt attaggtaga
     2821 attctagagt tgtgaaaaag aaagtggagg tccccatgtc aaaacattac tttgacccaa
     2881 gattaaaaat ttttgcgtta aattccaatc gcccattagc agagaaaatt gcagcagcag
     2941 tcggcgtcga gttaggaaaa tcatctgtta ctcaatttag tgatggagaa attcaagtaa
     3001 acattgaaga aagtattcgt ggatcgcatg tctatgttat tcaatcaacg agcagcccag
     3061 tcaatgataa cttgatggag ttgctgatca tgattgacgc actgaaacga gcaagtgcaa
     3121 aaacaatcaa cgtagtcatg ccttattatg gctatgcgcg tcaagaccgt aaagcacgtg
     3181 cacgggaacc aatcacagcg aaattagtag caaacatgat tcaaaaagct ggtgcaacaa
     3241 gaatgctgac tttggacctt catgcagtcc aaatccaagg tttctttgat attccagtcg
     3301 atcatttgat gggtgcgcca cttattgcca attatttctt agaaaaagga atcaaaggcg
     3361 atgatgttgt cgttgtttca ccagaccatg gtggtgtcac acgggcacgt aaattagcgg
     3421 aatttttgaa atctccgatt gcgatcatag acaaacgccg tccaaaagca aatgttgcag
     3481 aagtaatgaa tatcattgga caagtcaaag gcaaaacttg tgtactgatc gatgatatga
     3541 tcgatacagc aggtacgatc acattggctg ccaatgcttt gaaagaagct ggtgcaacta
     3601 gtgtgtatgc ttcatgtaca catccagtat tatccggccc tgctttacaa agaatagaag
     3661 attcagctat cgagcgtcta gttgttacag actcgatcta tcttccagaa gatcgtaaaa
     3721 tcgacaaaat cgatgaagta agtgttggcg gactaatggg agatgcaatc aaacgtatcc
     3781 atgaaaacaa accagttagt ccattgtttg aaacaaaaaa taaataataa ataaactcac
     3841 aaaggggagt ccaattgggc tgagattgaa tctatttcta aacccttcgt acctgtatcg
     3901 gttatgcgag cgtaggaatt gtgaataaac agctgtttga ctattttcga aagctgcttc
     3961 ctcctttgtg acttttttat tcaaaggagg aagttttttt atgggaaaaa atagagtttg
     4021 ggtagaagga acgattgttg cagcgttagc gatggtgttg tcgttgattc cgatccagat
     4081 cggcagcagt ttttctattt cattagggca gattccattg actctttttg cgttaagaag
     4141 agggacaaag gcagggatgc tggcaggttt catttggggc atcctacatt ttccgttggg
     4201 acaagtttat tatttaagtg tcgttcaagt gttgattgag tacccgattg cctatacttt
     4261 tgcaggcgca gcagggctca tggcttcaaa tgtccaaaaa ggctatgtag acgataatac
     4321 gaaacaaatt agaaaaagca tcgtgtttgg tgcattgatt ggcgcacttt ccagatattt
     4381 ttggcatttt attgcaggag tggttttctg gggagcgtat gcactatggg ggatgaatcc
     4441 ttggctcttt tctttcgtaa tgaatggtgc cagcgggttg agtacagcta ttgtaacgat
     4501 catcgtttta ttagggatcc aacaaacgac tccttcgatt tttgtgccag ataaacgaca
     4561 ggagctgtaa ataaaaaaga agcaagaaac ttgagacaga atcatgtcct agtttcttgt
     4621 ttccttttta ttttttgata agaaatagat ctacttcaat ggcagataag aaagatcggc
     4681 atcttctacc aattgccagt gtcgatcggt gacagagtag attaaagtag cgatgatttc
     4741 ctcttctcga taccgggtgc cttttaattt ccaaatataa tcttcaatca catagattgg
     4801 gatacgatat ttaccatcga tcaaaccaac ttgatcaaaa gaaaaaatga tcccttcctg
     4861 catcaaatta cgcatttctt tcaataattc cacactgatt ttttcaacag gtgtttcttt
     4921 tttgaaaaaa gattttttta cattgatctt atctgacaag atcgaactta atttactagc
     4981 aaaaatccta taaaattcat ctaaatagcg ataataaatc cgattcagct gatcattaag
     5041 atcgaagtat acaaaattat tctgtagttt ataaaaaaac ggcgaatgaa gatgtgtttt
     5101 catatgacca aaatataata attctgaaat ttctaaaggt gtcaattctt tcagcatcgt
     5161 taaatcagta aagtcgatcc acttcaattc atcgaatcca cgcctgttac gagaagagga
     5221 aaagaaacgc tgaatatttt ctgtaccacg gattactttc agccctgtat gggattcata
     5281 ttctccagca gaagcagatg gatcaagcaa gagcaagttt tgaggaaaat gcacgatact
     5341 gtttgcaaag tcagtagcag tcagcccttt tgttaaaaca gcattacttg tggtatcaat
     5401 atgtacataa actgactcag tcatcatgtt cctcctctta tttcctctta atctctttta
     5461 ttttacaaca tttgcattaa aaaagcttgt ttcttttatt ttaaaattcc attacaaaat
     5521 cacgttttca ttgaaaacac tctcattttc aattaatttt tgtgattttt gtattttttt
     5581 atttaaagga ggttttatga attgttttct tatggaatct acaaagtcga atacgagact
     5641 catgaccttt ttatgacgta ctggtatact tgaagaaaaa ggagagcgcg atggagataa
     5701 aaaaagttta cttttcacag aaaatgtcgc tgtattcgcc tatccagcaa gcaaaacaac
     5761 cccttccatt ttttcaaagt catcaagaaa gtagagacgc tttttggcgt tctgcaaaaa
     5821 agcaatgtgc ttttaaagca gtatcgaaaa aatataccgt ctattttact attgctaaaa
     5881 gtagaggaga tgttattttt aataatctgt tgattgaagg tgaaactttt gaatggaaaa
     5941 aattttttcg gtatatggaa gcttgcgctc gtttttttat taaagaaaac tgttgttttt
     6001 tatttcaatc tcctctatca gaagaatggt tgcgtatttt tcataaaaac ggctatcaag
     6061 gaaccacaca attaaataaa aagctggtct atcatacagc acttgtttta ggtggaggag
     6121 gagcgcacgg tgcttatcag attggtgtgt ggcaggcgct gaaggaacat gatatcaact
     6181 ttgagattat cacaggtacc tcggtaggtg cgttgaacgg cgcattgatt ttacaaggag
     6241 atatgaaaaa agctgtgaat ttatggaaaa agctgtcgac aagacaagtg cttgcgttac
     6301 cagaaatggc tgcagttgaa gaccttcgtg aacgcttcta tcgagaaaga cgccaaatga
     6361 cgaaaacagc actaattgaa ggcggggttt cttctgctcc attggaaaag atggtcaaag
     6421 acaatttgga tttgtcctta ctcaaacata atcccaaaat acgtttatat acggtgtcta
     6481 ctaaactgcc agaactagcg gaagtagtga ctgatatcca acagacaaaa acagaagaaa
     6541 taccagattg gatactcgcc tctgcttcat tttatcccgc tatggcttat cgaaagatcg
     6601 gaaaaaataa atatgcagac ggtgggtatc gcaacaaaat acctattgat attgcgatta
     6661 acaaaggagc aacagaggca tttgtcgtag atgtgcaagg gccaggccca gcgaaaaaaa
     6721 ttcgtatgcc agacattttt atccattgga aatgtcaaac attgtggaca ctaggcagct
     6781 ttctgctttt tgatagccaa aggaaccaat taaatttaca attaggctat ctggaaatga
     6841 aaaaacgatt aggctattac tatgggaact ggtatacatt tcattctgtt aaacctgcaa
     6901 gaacatactg gcgaggattt ttgtcttact taacaaaaga aattcagtta gaattatctt
     6961 ttttcaaaag cataaaattt tggcaaaaac tgcgtaattt atataagaac agggtcgtac
     7021 cagagacatg cggattggcg atgctagaac ttttagcaaa aaaacatttt ttactgccca
     7081 atgaaatcta tcaagtagac atgatgattc aaatgatctg ccaacaagat ataaaaagta
     7141 tgccggatga tttattggca caaattggtc aattaagtac tgaagaatgg cgaaggtatc
     7201 gaaaatacca gcaaaaaata caaaatgagc gcacgaaaac tgtttatttt gattatctgc
     7261 tacaaggaaa acgcaaggat cgtttgcagc atgaattgct taagcaacca gttgacacat
     7321 tactgatcct atatttatat tatctcaagg aggaacaacc atggcacaag aattttcata
     7381 tgaaatcgta gaagaaatcg ctatattgtc agaaaacaac aaggggtggc gtaaagaact
     7441 gaacctagtc agctggaatg gtcgcccgcc aaaattcgat cttcgagatt gggcgccaga
     7501 ccatgaaaaa atggggaaag gcctgacatt gacgaacgaa gagtttgaac aactgcaaaa
     7561 agcaatagaa aatatgtaat gaggaaggac cctgtcgaat gaaaagtatg actggttttg
     7621 gcaaagccat ccgcgaaaca aaagcgtatc agttagatat tgaaataaaa agtgtcaacc
     7681 agcgttttct agatgttcaa atacgaagtc ctaaaatcct gaactttgtt gaaaacgatt
     7741 ttcgtcagct tattaaacag cagttaagcc gcggtcgaat cgaagtattt gtgaatctag
     7801 cttatattgg caaaaacgaa aaacagatcg tcatcaactg ggaattgatt gattcactta
     7861 tcactcaatt gacagacgga attcaacaac gatacggtag tcaaaatcaa gtgtcaatta
     7921 gtcggatggc ggaacgcttc gtgctggacg aaaacttcgt aacggtagaa gaaaaaccgg
     7981 aagagagcat ggaagaattg gcacagttag ctctagatac attgaaaagc gcacttgatt
     8041 ctattgaggc gagtcgagaa aaagaaggtc aagctttagc tttagtgttg aaaaagaata
     8101 ctgaagaatt caaagaagta ctaaaaaaac tcgatagttt tgtagaaatc tatgaaaagg
     8161 aatttcaaat aaggtatcaa aaaaagctgg aggaatttct tggagcgaaa gtcgatgagc
     8221 aacggttgtt gacggagcta gccatcttgt tggaacgcgg agatattcac gaggaactgg
     8281 atcgtctggc gatccatgta caaaaactag atgaacttat cgaagcacaa tgtcctgtag
     8341 gtcgggaatt agatttcctg atccaagaaa tgaatcggga aatcaacacg atcggttcca
     8401 aatcaaatgc aatcgaaatt aaaaatcaag tcgtccagtc taagacgatc ttagaaaaaa
     8461 tcagagaaca agtacaaaat attgaatgac gaaagaggta gagataatga aatattatga
     8521 cgtaacgttc cacgaattaa gtggaaaaac tgtggttaaa cgggatatcc cttctgaaaa
     8581 aaacggcttt gacgtatgga aagatgcctg tgcagactat aatgagaacg aactgtttat
     8641 tttgatcaac gacggtgctt acgtgacgat gaatcggaaa tttattgttc gaattgacac
     8701 agaagaggta gaagatccga cagaaaaagc acgttctcga aaagatgaga tcatgggtgt
     8761 agtgaatact ttgtccaata tgggctttta gcaaggatgc tgaacaaaga aatacaataa
     8821 ataaacagaa ttggatttct tcgcttagct tctttgctct aggaatacat ttaaaggttg
     8881 tgacaaaatt cgtgtcacaa tcttttttta ttttgaataa gtgatgttca aaaaccattt
     8941 tctcggtatt aagccaaatt tatgcaaaaa tgtgagaaac tattttcaca aaatttttct
     9001 tcatactcga aactaatcgg cttcttcacg acctcttata cacggcgttc aaaagcttgc
     9061 atctgcgata ataaccccaa ccaaacgaaa aacatgagaa gctgtttatg tttggctgtt
     9121 cttattactt gatgcaggac agctttttta cgacctcttg gtacagggta gcttttttac
     9181 caatttctag ctataattaa agataacctt gaaagttgca gaaaaaaagt gcaaaataaa
     9241 cgataagtac aaaaagacta gttgaaagga cgtcgtcatg tcagagcgtg gattattaat
     9301 cgtgttgtct ggtccatccg gtgtaggaaa aggcacagta cgaaaagcaa tttttgagag
     9361 tgaggataat gattttcagt attcgatctc aatgactacc cgtaaaatgc gtgaagggga
     9421 ggtcgaaggc gttgattatt tcttccgaag caaagaagag tttgaatcaa tgatcgaagc
     9481 tggagagatg ctggaatacg cagaatatgt cgggaattat tatggaactc ctttgtcata
     9541 tgtcaacaag acattggatg aaggaaaaga tgttttcttg gagattgaag tccaaggagc
     9601 aaaacaagtc aaagaaaaag tgcccgatgg tgtattcatc tttttgactc cgccagattt
     9661 agcggaatta aaatcacgga tcgtaggccg aggaacagat gcagatgaag taatcgaaaa
     9721 acgaatgaaa gttgcaaaag aagaaatcga aatgatggct ctttacgact atgctgttgt
     9781 aaatgatgaa gtgccgctag cagttgaacg aatcaaaaac attattgcca gtgaacattt
     9841 tcgagtagat cgcgtaatcg gtaaatatat taaaatgtta aaggagatgt agtcttatga
     9901 tgttaaaacc ttcaattgac tcactattag atcgtgtaaa ttcaaaatat tctctagtga
     9961 ttttagcaag taaacgcgcg catgaattgg atgcaagtgc acagcctact ctagattctt
    10021 ttgattcagt aaaaagcgtc ggtcaagctt tagaagaaat cgatgcagga aatgtagtca
    10081 atgatccaca tcctgaatta aaacgtgaac gtttgaagat ggaagaagag gaacgtcaag
    10141 cacaaaaaga gcgtgaacaa cacgaattgg aatcacgtat ccgtgaagag caaaaaatgt
    10201 aataaagaaa aatagagcga acatctaaaa agaaaagcaa acccagctgt ttccttttca
    10261 aacattcgcc acttattgtc tggtagaaaa ggctgtgtct gaactttttg acacagttct
    10321 tttttttctt atctgctgtt aattttttgt taggatttgg cagaagataa gacaaatcca
    10381 tcgatctcta gtaaaatagg caaggaactt tttgtcgctt gataagaaaa gacaaaaaaa
    10441 ggaggaaacg aaccatgaca ttaacagctg aagtcattgt ggacgtacct actatgcaga
    10501 ccgatcagcc attcacttat ttggttccct ctgaaatgga aacagctttg caagtcggga
    10561 tgcgagtaga agtccctttt ggtaatggca atcgtcatgt ccaaggattt gttatggcta
    10621 tccaaaaatc agaagaatca gctaatccat ctttgaaggc agttattcgt ttgctagacc
    10681 ttgctccggt ggtcaatgaa gaattacttt cattagctga ttatatgaaa aaaattactt
    10741 acgcattcaa aatcacttgt ctacaaacga tgcttccgag tgtgatgaaa gcagaatatg
    10801 ataaattgat ctatcctttg gcagacacac cagaagttca ggtattgttt gatcagcgag
    10861 aagtgatttc ctggaaggaa gcagaagaag aaggcagcct ttctcaattg attcgctggc
    10921 gccaagagca attagtagat atcaaatatg aagtccatac acgaaataaa gtaaaaacga
    10981 ttcgtttggt ccgttctttg ttaactgaaa agcaaatcga agaagaatgg gcaaaattac
    11041 ggcaaaatgc caagaaacaa aaagaacttc ttttgtgttt atctgaactg agccaagaag
    11101 aaccaattgc ttatttcaaa aataaaggaa tcagtactgc tgtcttgaat caaggaaaag
    11161 aaaagggctg gctggagttt atagaatcag aacgttatcg cgacccttat aaagaccgag
    11221 tatttgacca aacgacggca ttggaactga atgcagaaca aaaaaatgct gtcgaacaaa
    11281 tcatcacagc aggtcagcag caaaaagatc aggtcttttt gctggaggga atcactggca
    11341 gcgggaaaac agaagtatat cttcaggcaa tcgctgatgt tttgtcagaa aataaaacgg
    11401 ctattatgtt agtgcctgaa atcgcattga ctccgcaaat ggtcgagcga ttcaaaggac
    11461 gcttcggaga atcagttgcg gtcttacata gcggactttc ccaaggtgaa aaatatgatg
    11521 aatggcgcaa gattgagcgg gaagaagcgc aagtagtagt aggcgcacga tctgctattt
    11581 ttgccccgct gaaaaatatc gggctgatca ttatcgatga agaacatgaa tcaagttaca
    11641 aacaagatga gacaccgcgt tatcatgcga gagatctagc aatttggcgc agtaaatatc
    11701 atcattgccc aatagttcta ggaagcgcga cgccctcttt agaatcaaga gcacgagctc
    11761 aaaaaggcgt ttatcagtta ttgcagttaa accaccgagc caaagcagct gcacagcttc
    11821 cagctattga gatcgtagat atgcgtgaag agtttcagaa tcatcggacc tctacttttt
    11881 ctgctaattt gcaggaaaaa atacaaaatc gattagacaa aaaagaacaa actgtcctac
    11941 tgctcaatcg tcgaggatat tcgtcttttg tgatgtgtag ggactgtgga tttgttcttc
    12001 catgtcctaa ttgcgatatc tctcttacac tgcatatgga tacacgttca atgcgctgcc
    12061 attattgcgg acatgaagaa cctattccca atcgctgtcc taattgtggc ggcaataaaa
    12121 tccgctacta tggaacaggt actcaaaaag tagaagagga actccgagaa ctttatccgc
    12181 aagctaggat tttgcgtatg gatgtagata ccactcgaag aaaaggggca cacgaacaga
    12241 ttttacaaaa attcggtgca aaagaagcag atatattatt agggacacaa atgattgcta
    12301 aaggtttgga ctttccagaa gtgacattag ttggggtgtt gaatgctgat acctccctga
    12361 atttaccgga ttttcgttct agtgagcata cattccaatt gcttacccaa gtttcaggac
    12421 gagcagggcg agcggaaaaa gcaggcgaag tcgtgatcca aacattcaat cctcaacatt
    12481 acgccataga attggctaaa aaacaaaatt atgagcagtt ttatcagcag gaaatgcatg
    12541 tacggcatcg tggaggctat cctccttatt actttactgt gaaaataacc gccagccatc
    12601 ctgaagaaca agtagcggca aagaaaatct ttcagattgc caatcagcta aaagaagtgt
    12661 taagccctca aagcttgcta ttagggccaa cgcccagcat gattttgaga gtgaaaaacc
    12721 gatattatta tcaactaatc atcaaatata aacatgaacc gaatcttcct catgttttgg
    12781 atgaaatttt gaatggaagc cagaaagaac agcgacaagg tctttttgtg gcaattgaca
    12841 acgaaccatt aaactttatt taagaaaggg ccaaattatg cgctatccta tattgatcca
    12901 ccctaatgat aaattaaaaa gaactgctca gccaatcgat gtaatcacgg acgagacaat
    12961 cgctttatta gacaatttat atgagacaat gattgcgaat gacggaatag ggatcgctgc
    13021 tcctcaagta ggacaaaaca agagaattgc tgtgatcgaa gtagatgaag gcgagaaatt
    13081 tgaactgatt aacccagaaa tcatcgaagc aaaaggtgaa agccttgacg tagaaggttg
    13141 tctcagtatt ccgcatgtct atggaacggt caagcgagca gatgaagtga ccgtgcgtta
    13201 ttatgatcga gacggagaag agatagaagt gacggctttt ggctatttag cccgtgcctt
    13261 ccagcatgaa atcgatcact tagacggtat cttgttcatt gagaaaatga tacagcagat
    13321 cccggaagaa gaacttgaag aatatatgga ggaacatctt gatgactaag ctagtattta
    13381 tgggcacacc tgctttttct gtgccgattc ttgaagggct gatagaatca ggttacgaga
    13441 tccaggcagt ggtaacacag cccgaccgtc cagttgggcg gaaacgagta attacgccga
    13501 caccggtaaa aaaagcggct ctgaagcacg gtatccgtgt gctgcagcca gagaaaatct
    13561 ccggttcgcc agaaatggaa gaaatcattg aattggtgcc tgatgtgatc gtcactgcgg
    13621 catttggcca attcttgcct gaaaagttat tgcaagtacc aaaattaggg gcaatcaatg
    13681 tccatgcttc tttacttcct aaatatcggg gaggtgcgcc tgttcattat gccatcatga
    13741 atggggagaa agaaactggt gtaacgatca tggaaatgat caaaaaaatg gatgcaggcg
    13801 gaatctatgc gcaagaaagc ataccaatca ctaaacaaga tgatgtaggg acgatgtttg
    13861 aaaagcttag ccttttagga agaaagctat tgctagaaac attgcccaat attttggatg
    13921 gacaaaaacc agtacctcaa gacgagtcag aagcaacttt ttcgccaaac atcacacggg
    13981 aacaagaagc aatcgattgg cataaaactg cagaagaaat tgacaaccaa gtacgcggaa
    14041 tgcgtccttg gccaattgca ttcacgacct atgagggcat acgctggaaa ttattatcgg
    14101 ttgaagtatt ggcagaaact acagacaaag cacctggtac gatcatccgg aaagacaaaa
    14161 aaaatctatg gattgcttgc ggtaaacaga ccgtcttagc catcaatgaa ttacagccag
    14221 ctggtaaagg aaaacaggcc gtacatgatt tccttaacgg aagcggtcag caagttcaga
    14281 ttggtcagca ggtgaaataa tgaaaaaaat ccctaaaaaa atgaaaaaat cagtacgata
    14341 tatggcatta ctgacattag agcgagtgaa caagggtggc gcctactcga atcttttgtt
    14401 gaatgagatg atcaaacaaa gcgagctaaa tcaaaaagat gtgggtttat ttacagaatt
    14461 gatctatggt acgattagcc atcagcgact attggaattt tacgttgcac cattgatcgc
    14521 taaagcaaaa aaagtggatg actgggtcaa gatgcttctt tatctttctg tataccaatt
    14581 agaattttta gataaagtcc ctgcacatgc tattttaaac gaggcggtcg aaatcgcaaa
    14641 agtaaaagga aatcctggga cagggaaatt tgtaaatggt gtcttgagga attatcagcg
    14701 tcaaggagca ccagatctgc aaggcattgc tgatcctatc gaaagacttt ctgtcaaaat
    14761 cagcctgcct ctatggatga cgaaacgact ggtggatcaa atcggatacg aagaaactga
    14821 aaagctcggt ttatcgctat atcagcctag ccatgctagt gcccgagtag atacacgccg
    14881 actttccaga gatcaggcca tcactgtttt gcaagaagaa gagatcacag ctgaaaaaag
    14941 ccaagtcagt ccatacggta tagtagcgaa aaaagggcat ttagcttcta gctcattgtt
    15001 ccacgatggc gtcatgacga tccaagatga aagttcgatg cttgtagcgc cgtctatgca
    15061 aatcgagcct gaacatcatg tcttagatgc ctgtgcagca cccggaggta agacgacgca
    15121 tattgcttct tttttagatc cgtcatgcgg tggagaagtg gtcgctttag atgtacacga
    15181 acacaaagtc aaactcattg aagataatgc agcacgtcta ggtgtctctt ctgctgtcta
    15241 cgctcaaaag atggatgcta gagaagtcag taaacagttc gaagcagagc agtttgatcg
    15301 gattttagta gacgcgcctt gttcaggtct tgggctgctt cggcgaaaac cagatattcg
    15361 ttataaaaaa cagccggatg aattagcgaa tttaccaaaa atccaattgg aaattttaga
    15421 aagctgcgca ccaactttaa agtcttccgg tattctgact tatagcactt gtacgatctt
    15481 aaaagaagaa aaccaagacg ttgtttctgc tttcttggaa agacaccctg attttgagag
    15541 gattgatgtt ttgaccaatc ctatgctaca atcatcaatc gaagagaaaa tgttgacttt
    15601 gtatccgcat cagttttaca cagatggatt tttcatttgt tgtttgcgca aaaagtaatg
    15661 aggtgaaaaa atgcagattg aatatcaatc agatgtagga agacgacgta acacaaatca
    15721 agactatgcc agtgtattta ccagccgttc aggtctcaag cttgctgtat tagcagacgg
    15781 gatgggtggt catcgtgccg gagacattgc cagtcagatg gcggtaacga atctaggcga
    15841 agcttgggaa aaacaagaag ctgttgacga tgaaaaaatc gcccaatggt tcattcaatc
    15901 gattcaagaa gaaaatatgc tgatttatca gcgtggacaa gaacagccgg aatataacgg
    15961 tatgggaaca acaatcgtag cggccgctct gtcagatgac tggttcacga ttgccaatgt
    16021 tggggatagc agagcttatt tgattcgtga agataaaatc atgcaattga cggaggatca
    16081 ttctttagtc aatgaactag tcaaatcagg agaaatcagc gaagaaatgg cagtgaacca
    16141 tccaaggaaa aatattttaa cacgttctgt cggcatgcct ggaacagtcg aagtagatgt
    16201 ttctactcat ctttggcaac taaaagatcg actgctgtta tgttcagatg gcttgacgaa
    16261 catgctgtct gaagaagaaa taggaacgat catcaatcaa gaaggcccat tgtctcataa
    16321 agtaactgag ctgattgatc gtgccaatga agcaggcgga gcggataata tcaccgttct
    16381 tcttatcgaa tataaggagg acagtgtatg atcgagttgg gcaaaaaatt aaatggccgt
    16441 tatcaaatca ctggaaatat cggtagcggt ggtatggcaa atgtattttt ggcgcacgat
    16501 ttaatcttgg atcgtgatgt agcagttaaa gtcttacgat ttgactttca aaatgaccag
    16561 actgcgattc gacgatttca gagagaagct ttagcagcaa cagaactcgt tcatccaaac
    16621 attgttagtg tttacgatgt tggtgaagaa gacaacatgc agtatctggt gatggaatac
    16681 gtcaaaggaa tggacttgaa acgatatatc caaacacatt atcctgttcc ttatgaaaca
    16741 gcagtaaata ttatgcagca gatcctttct gctatttctt tagctcataa ccatcaaatc
    16801 atccaccgag atttgaaacc ccaaaacgta ctgatcgata atgaaggtgt tgtaaaaatc
    16861 acggatttcg ggattgctat cgctttatct gaaacatcga tcacgcagac gaatacgatg
    16921 ctaggatctg ttcattatct gtcccctgag caggccagag gaagtatggc aacgaagcag
    16981 tcagatattt atgctttagg gatcatcctt tatgagatgt tgacgggtag cgtaccgttt
    17041 gatggtgaat ctgctgtaac aattgcttta aaacattttc aagatgatct tccatctata
    17101 aaagcacttg atccaaatgt gccacaagca ctggaaaacg tgattttacg ggcaacggct
    17161 aaagaacctg cagaccgtta taagtcagcc gaggaaatgt ctgatgatct ttctacagta
    17221 ttatcaccag ctcgtgcaaa cgaagaaaaa tggcagcctc atgtgatgga taatgaaaca
    17281 aaagttatca caccccttac ggaagatgca ccaatgcctg attcattcaa atctatgcct
    17341 ctgccaaaag acaagccaga aaacgaaacc ttaccagagg aggaagaagt tctgcctgat
    17401 cctaaaaaga aaggacagaa aaaatggtgg ctgatcctat tagctattct tgctgtttta
    17461 ggaatcggaa cagctgtatt ctttgcttct ggcgggcgag gagaagttgt tgttcctgat
    17521 gtttctgatc tttctgaagc ttctgctaga gaaacactcg caaaagcgaa attagaagta
    17581 gcaacaaaaa cagaagaaat tgcagatgac aaaatcgaag aaggtaatgt agtgaagaca
    17641 gacccggcag cgggaacgac agtcaagcaa aaacgcgaag tcactctgta tattagtagc
    17701 ggcacgaaaa aaatcaaatt agatgattac agtggtaaaa gttatgaaga tgccgaagca
    17761 agtttgaaag aattagggtt ttctgctgac ttgattcaaa aagaagagga attcagttca
    17821 gaggtagaaa gcggaatgat catttcgcaa tctccatcag aagatacaga agtcgatcct
    17881 aaaacagaca cgattacttt cacagtcagc aaaggaccag aaacagtgac tttgagtagt
    17941 catgtaggag aaaactacga aactgttcgt aattggcttg ttacacaagg attcaatatc
    18001 aataatatta gtgctactta tgactatagc gacactgtac catcaggttc gatcatcagt
    18061 caggatccag cctcgggtga agttgtagca gaagaaactt acatcaattt tgtcgtaagc
    18121 caaggaacag agcctaaatt gaatgatatc tccggctata caaaaagcga agcacaaagt
    18181 tatttagcta gtgtcggtgc agaatatatc gggcatgaga cttccgaata ttcaaacacg
    18241 gtggataaag ataaagtgat tcgtacagta ccaggggcag gaacgacaat taccaaagga
    18301 atggttgtga acgtaattta ctctaaagga ccagatccag cgtcttctag ttctgaaaaa
    18361 gactcttcag acagttctag cagctcaagt agctccagta gcacaagcaa ctcttcaaaa
    18421 gaagaatctt ccagctccac aagttcatca gctagcacct cagaaagttc aaaataagtg
    18481 ctgaataaaa tatatcagaa gggaatgcga cattgatttg ttgcattctc ttttttgtgt
    18541 ttctatctct tttgatcaat tttcaagcca tatactttga gaagtttgca tggaataaca
    18601 cctactttcc tcttcgtatg gtaaaataaa caaaaacgga ggtggcactt atcaaaggac
    18661 aaatcagaaa agcaatcagc ggtttttact atgtatacgc aaacggagag acctatcaaa
    18721 caagaggaag aggaaatttc cggaatcgga aaatcacgcc gcttgtcgga gatcaggtga
    18781 tctttgagag tgaaaatcaa acagacggct atcttctgga aatcttgccg agaaaaaatc
    18841 aattagttcg cccaccagtc acaaatgttg atcttggaat cattgtcaca agtatcgtag
    18901 agcctgcatt ttcttataat ctacttgacc gctttctagt taccttggaa tacgagtcga
    18961 tcgaaccgat tatttttttg acaaagaccg acttgtcaga cgacccagaa aaaatcgaag
    19021 agatcaagca aacctatact aaaataggct atccggtgat tgtacccaat catacgggtg
    19081 atacgacaga actgatccgt tacttcccag aacggctatc ggtctttatg ggtcagtctg
    19141 gagcaggaaa atcgacgcta ctgaatcaaa tatcaccgga actgaattta gcaacaggag
    19201 agatttctga tgcacttgga agaggacggc atacaacacg tcatgtggaa ctgattccta
    19261 tctatggcgg gttagtagca gatacaccag gatttagctc gattgacttt ttgacaattg
    19321 aagcaggaga actgccgaga caatttcctg aatttgtaga agcttctgtc cattgcaaat
    19381 ttagagagtg catgcatgct aaagaacctg gctgcgaagt aaaacataga gtagaaacag
    19441 gtggtatcgc acagacacgt tacgacaatt atttgcaatt cttacaagaa atcgaaaaaa
    19501 gaaaaccaat gtatgcaaaa aaagaaggta aacgaaaata ggaggaaaca agaatgaaga
    19561 tagcaccatc cattttgagt gcagattttg ccaatttaca aagagacatt gagttagtgg
    19621 aaaaaggagg cgcagattac atccacgtag atgtaatgga tggccgattt gtcccaaata
    19681 tcacattagg gccaaatatt gttcaggcaa tccgtcctgt tactaaatta ccgttagacg
    19741 tccatctgat gatcgttgat ccagaaaact acattccagc atttgcaaaa gctggagcag
    19801 atatcattac tgtccacgtc gaagcaactc ctcatattca tcgggcactt caaatgacaa
    19861 aaagcttagg agttaaagct ggagtagtta tcaatccagg aacaccagtc tccatgatca
    19921 aacatgtttt gcctttggct gatcaagtac tagtcatgac tgtcaatcct gggttcggcg
    19981 gacaaagctt tattgaagaa acagtagaaa aaattacgga actcgctgat ctacgtagag
    20041 agaacaattg gacttatgca atcgaagtag atggcggaat cgttccagaa acagcaaaaa
    20101 tctgtaaaga tgcaggggcg gatgtcttcg ttgcaggatc atatatctat ggagccgaaa
    20161 atccagtcgg acaaatcgaa cgattaaaag aggcattaga ctaaatgaaa attttattag
    20221 ctgctggagg taatccgcaa aactggccgc agtctctgct gtccaaatac gatgcctatg
    20281 tcgggataga ccgtggtgcg ctgtacctgc ttcaagcagg ctacccagta gatctggcag
    20341 tgggtgattt tgattcattg tcgaacgaag agcagaagga agtatttgca aaagccaaag
    20401 agtatacccg ttcccctgca gaaaaagacg atacagatac acagttaggt atcttaaaaa
    20461 catttgaacg ttacccgcaa gcggaagtca ctttgattgg agctacgggc ggaagattgg
    20521 atcatctttt agccaatctc tggttaggta tggaacctcg cttcaaaccc tttgcccatc
    20581 agcttattat cagagattgt caaaattatt tgtcttatta tttgcctgga gagcatatag
    20641 taagacagat accagatatg aagtatttag cttattgctg cttgactccc gtctcgaatc
    20701 ttacattaaa aggcagcaag tatgtattgg aaaataaaga agtagaatat ccgacatctt
    20761 atgcaagtaa cgaatttctt tcagataccg cagaattttc tttttcagat ggtatgattg
    20821 cagttattca aagcaaagat tgatccataa acaaataaaa aaatttgtct ttcaggctaa
    20881 aaatgacaga atctattatt tgctaaaaaa aagcttaaga ggagcaactt accttttgtt
    20941 tcacggcatt tagtgataaa attgaacaca agagtctaat taattcgagg tgtctttgtg
    21001 aagaagttca atcctaataa aaatattatt attaccttgg ttattgttat catcgtggtg
    21061 acgatactaa gtgtgaccgc tgcgcagcga gcgaatgaag gaaagcccaa tttcttccaa
    21121 tccatcgtta atgacagtgt tgcaatggtt gataaaacaa tctctgcccc agtacggtgg
    21181 gtacgaaatg gagtagattc tgtccataat cttttttcaa cttatgccga aaatgagcgg
    21241 ctaaaagaaa aaatcgatag ctatgatgac gtttcacagc aaaacaagaa ttacgagaga
    21301 gaaatcgaag cgttgaaaaa agaacttgag ttgaatcaga cgctgactag ttacgaaaaa
    21361 gtaacggcaa atgtcattac tcgttcgcct gacagttggc aggacatgct gatcgtagac
    21421 aagggttcta aagacggtat cgaagcaaat atggcagtca tgtcgcaaaa aggattgatt
    21481 ggccgagtga tcgaggtcaa tacggcttcg tctaaaatcg aattactgtc atcctctaat
    21541 gaaagctcca atcattttcc agtacgggta tcttcggcta atggcgaagc gtttggtttg
    21601 cttaaaaact atgatgaaaa gctccatgcc ttagtggtga cccaattaac tggtgatacg
    21661 gatatcaaag aaggggatgt tgtccagaca tccggtcttg gagggaattc tccagctaac
    21721 ttgccgatcg gtacggttat taaaacgaaa ccagatagtt atgggctgga tcgggaagtt
    21781 tatgtgaaac cttatgcaga aatgtatgac gtgtcagttg tgacgattgt ccaacggcta
    21841 gcggaggatt agtccatgtt gaagaaagaa acaatgaagt actatctgcc aatcgttttg
    21901 ttctttttga tgttgataga tggtcattta acaagaatgc taggggagtg gtcgaaaggc
    21961 acctatatgt caaatgccca ctttctgata ttggcattat tatgttgcag tatggcgttt
    22021 gaaaaacgtt atttactgat taccacgatt gttctcgggg ctatctatga cgcttactat
    22081 attggcgtta tcggtatcta tgcagtagct ctccctttaa ttgtatggtt gatgtatgta
    22141 atgaaagacg ttatccatgt caacatcttt actgaatttt tcagtatgat catctttgtc
    22201 acgggttatg aattgtttac gatggtggtc cagttgattt ttaaattagc agtagtaaat
    22261 aacacgtatt ttattacaag gtttttagga cctacactgc tgttgaacat gattatattt
    22321 gtattattca tttttccctt taagaaatta ttcagtgatg aataatttct ttttttattt
    22381 ttaggtcgaa agcgaaaaag aatcgttgtt atcttaagaa atgctagact taacgcggct
    22441 ttttcatgat cattttctga aacgaacagt tttgtcattt ttaaaagttg ttttgaaaca
    22501 tttttgtaac ataactatta tatcgttgac acactgctat ggtacaattt ttatatcgtt
    22561 aagaaagact taaatatatt tagatattta ttaaattaag ccagtcggag gaatgaagag
    22621 tgaaaaagag tttaatatca gcagtaatgg tatgttcaat gaccttgact gccgtagcat
    22681 caccgatcgc tgccgcggcg gacgattttg attctcagat acaacagcaa gatcaaaaga
    22741 ttgcagactt gaaaaatcaa caagcagatg cacaatcaca aatcgatgcc ttagaaagcc
    22801 aagtttctga aatcaacaca caagcacaag acctattagc aaaacaagat acattgcgtc
    22861 aagaatctgc acaattagta aaagacattg cagatttaca agaacgtatt gaaaaacgtg
    22921 aagatacaat ccaaaaacaa gcacgcgaag cacaagtaag caacacaagc tcaaactaca
    22981 tcgatgctgt attgaatgct gattcattag cagatgctat tggacgcgtt caagcaatga
    23041 caacgatggt aaaagcaaac aacgacttga tggaacaaca aaaacaagat aaaaaagctg
    23101 tagaagacaa aaaagctgaa aacgatgcta aactaaaaga attagctgaa aaccaagctg
    23161 ctttggaatc tcaaaaaggc gatcttttat ctaaacaagc tgatttgaac gtactgaaaa
    23221 cttcattagc tgctgaacaa gcaactgctg aagacaagaa agctgacttg aaccgtcaaa
    23281 aagcagaagc tgaagcagag caagctcgta ttcgtgaaca acaacgtcta gcagaacaag
    23341 ctcgtcaaca agctgcacaa gaaaaagctg aaaaagaagc acgcgaacaa gcagaggctg
    23401 aagcacaagc tactcaagct tcatctactg cacaaagctc agcaacagaa gaatcatcag
    23461 ctacacaatc ttcaatgact gaagaatcat catcagctac acaatcttca gcaacagaag
    23521 aatcaacaac acctgaatct tcaacagaag aatcaacagc gcctgaatct tcagcaacag
    23581 aagaatcaac aacag
//
LOCUS       DAZKCH010000041        23414 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000041 DAZKCH010000000
VERSION     DAZKCH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.041"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(33..1076)
                     /locus_tag="ACG84X_001613"
     CDS             complement(33..1076)
                     /locus_tag="ACG84X_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9127485.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
     gene            complement(1237..1920)
                     /locus_tag="ACG84X_001614"
     CDS             complement(1237..1920)
                     /locus_tag="ACG84X_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HFP9127486.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            2115..3044
                     /locus_tag="ACG84X_001615"
     CDS             2115..3044
                     /locus_tag="ACG84X_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFP9127487.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            3105..3896
                     /gene="phnC"
                     /locus_tag="ACG84X_001616"
     CDS             3105..3896
                     /gene="phnC"
                     /locus_tag="ACG84X_001616"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HFP9127488.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            3868..4647
                     /gene="phnE"
                     /locus_tag="ACG84X_001617"
     CDS             3868..4647
                     /gene="phnE"
                     /locus_tag="ACG84X_001617"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HFP9127489.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            4644..5426
                     /gene="phnE"
                     /locus_tag="ACG84X_001618"
     CDS             4644..5426
                     /gene="phnE"
                     /locus_tag="ACG84X_001618"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HFP9127490.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            5429..6232
                     /locus_tag="ACG84X_001619"
     CDS             5429..6232
                     /locus_tag="ACG84X_001619"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9127491.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            6316..7863
                     /locus_tag="ACG84X_001620"
     CDS             6316..7863
                     /locus_tag="ACG84X_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HFP9127492.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(8160..8357)
                     /locus_tag="ACG84X_001621"
     CDS             complement(8160..8357)
                     /locus_tag="ACG84X_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127493.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(8433..8633)
                     /locus_tag="ACG84X_001622"
     CDS             complement(8433..8633)
                     /locus_tag="ACG84X_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFP9127494.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            complement(8753..9940)
                     /locus_tag="ACG84X_001623"
                     /pseudo
     CDS             complement(8753..9940)
                     /locus_tag="ACG84X_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9985..11111)
                     /locus_tag="ACG84X_001624"
     CDS             complement(join(9985..10883,10883..11111))
                     /locus_tag="ACG84X_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9127495.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(11515..12297)
                     /locus_tag="ACG84X_001625"
     CDS             complement(11515..12297)
                     /locus_tag="ACG84X_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127496.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(12362..13198)
                     /locus_tag="ACG84X_001626"
     CDS             complement(12362..13198)
                     /locus_tag="ACG84X_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFP9127497.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(13216..14625)
                     /locus_tag="ACG84X_001627"
     CDS             complement(13216..14625)
                     /locus_tag="ACG84X_001627"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9127498.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(14639..16462)
                     /locus_tag="ACG84X_001628"
     CDS             complement(14639..16462)
                     /locus_tag="ACG84X_001628"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFP9127499.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(17305..17631)
                     /locus_tag="ACG84X_001629"
     CDS             complement(17305..17631)
                     /locus_tag="ACG84X_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127500.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(17677..18039)
                     /locus_tag="ACG84X_001630"
     CDS             complement(17677..18039)
                     /locus_tag="ACG84X_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFP9127501.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(18076..18290)
                     /locus_tag="ACG84X_001631"
                     /pseudo
     CDS             complement(18076..18290)
                     /locus_tag="ACG84X_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            18418..18753
                     /locus_tag="ACG84X_001632"
     CDS             18418..18753
                     /locus_tag="ACG84X_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9127502.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(18829..20826)
                     /locus_tag="ACG84X_001633"
     CDS             complement(18829..20826)
                     /locus_tag="ACG84X_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127503.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(20924..21199)
                     /locus_tag="ACG84X_001634"
     CDS             complement(20924..21199)
                     /locus_tag="ACG84X_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127504.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            21431..22165
                     /locus_tag="ACG84X_001635"
     CDS             21431..22165
                     /locus_tag="ACG84X_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9127505.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            22204..23346
                     /locus_tag="ACG84X_001636"
     CDS             22204..23346
                     /locus_tag="ACG84X_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9127506.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
BASE COUNT         7224 a         4623 c         4094 g         7473 t
ORIGIN      
        1 actgtagaca tcatccataa aatggacttt gtctacagtc tgaaatcacc actgatgatt
       61 ttctcttttg cgtctgaaac tgcctgatag gcttcctctg ataattgtcc ttttgtcaga
      121 tctacccctt cttctttcaa accaaaggtc aaatgcttgc cgccaggaaa tttatcgtta
      181 tgagaagttt ctgcaaattc tttgacttct gcaccgacat ttttctttgt agaagtcaac
      241 gtgaaattcc ctgtctcgcc gttctccatt ttataatccc cttcatccgc ttgatcgcga
      301 tctacaccaa tcacccatac ttttctgcta tagtcgtttt cattgcgggc ttttgcttct
      361 tggaacaccc cagctccagt acttcctgcc gcctgataaa gaatatcgac tccctctttg
      421 tacatagaag cagcaatagc ttttccttta tctagcgaat cataggatgc agcatattgt
      481 acgttaacag taatttcctt gttcagtgct gtggcccctg ccttaacgcc agcttcaaat
      541 ccgctttgga aacgttggat cacgggccct tccattccac caataaagcc tacttgatca
      601 ctttttgtcg tatatgcggc agctagtcct gctaaatacg cactttcttg atctttaaag
      661 gttgctgatg agatattctt tttcccagta atctcaccat ctaccaaggc aaatttcaac
      721 tttggattat ctttagcagc attttccagt tcctctgctt gcaagtagct caagctaata
      781 atggtggtaa agccgtttct gattgcctga tcgatattgg tactgttatc ctctggattg
      841 ttcgtttcta tatacgtaaa atcttttttt gctgtcagct ttttctcttt tccccaagcc
      901 tctaatcctt cccagccagc ttgattgaag gagcggtcat caaccccgcc aaatccaaga
      961 accaaagcga ttttactttt ctctttttca ctttgcttct ccccctgaga ctgactacag
     1021 ccgactaacg ttactaatga caccaaaaac aacaatgaaa caagtatttt cttcaaaatt
     1081 tttctcccct ttttatgtgt cttgacacat tgaactttta aaagtatagc ataccaatat
     1141 atagaacact actcttcaac gaagattttc cgtttcccaa tttctccact atcaaaaaac
     1201 cagcaatcac ttctgactgc tgttttttta tagctgttat tctgctttta ctggactact
     1261 tatattctca gctaagtcct ctaaagcttc gatatcatga atcaagtaat aattcttttt
     1321 cttttcgata atattctcct cacgaaaatt cgtgattgtt cgtaaaagat gtcgataact
     1381 gacatttaag attgaggcgc aggtggttaa ccgaaatgag aaacgttcgt tttcgtgatg
     1441 ggtcaaaata aactttgcta aacgagtttc aacaggttct gtcagtgagt tcgccaaatt
     1501 tatcccggaa tttaaacgat aacttagtaa ctggcaaata ttctgcaaaa agcgaacatc
     1561 tttttgaagc tgtgttcgat attgatttag cggaatgctg atacagatgc acttagtcac
     1621 tgctttaacg ctgcttttcg gcgataattc ccacaatgaa gaggcttcgc cgagtggtgt
     1681 agcgggcttt gcgtaatcga tgcaaatatt ttgtgtatca gaagaatacg agtacaccat
     1741 taccgtccca tccactaaaa aatacaaata atctgaggtt tttcccgttt gaatgaggtg
     1801 ctcttccttt tcaaaaaaaa gtaaagaagc cattgccaat atatctgaat ccatataatc
     1861 ctgcaggttg tgcttctcaa cgtaagcagt taattgcttc gtatcatgga tttttttcat
     1921 gaaatcgtca cctctaagaa gtttttcttt attatagctt agattgtttt tcggctcaat
     1981 acgaataatt atttataatt gtttgtaaat tgtatgtaaa agttgtgtaa aataggacgt
     2041 gcgtcacttc attgattttg attccctgct atgatttaga cgtattagaa attatatcca
     2101 acaggaggag aaaaatgcag ttcaaacagt tagcaaaagg gttcatcgga gtcatgttat
     2161 tgaccacttt ggcggcctgc ggttctggga atacaagtag cagctcagaa aaagagagca
     2221 aagaaaaatt agttgttcaa ttcgttccaa caaacaatga tggtagtatg gaggcaaaag
     2281 caaaaccatt tgctaagtat ttatcgaaaa agttagatcg tgaggtagaa gtgacgttag
     2341 ctactgatta ttcaacgatc gtcgaagcga tgtcttctgg tcaagtcgat gtcggaatta
     2401 tgccgcctgc agcctatgtt caagcaaagg atgctggagc tgcagatgca atcctgactt
     2461 ctcagctcgg cgattatgat caagaaactg gcttgccatt aaaggacaaa cttacgaaca
     2521 cctttaaagg agaagtattg gttcgtgccg atagcggatt gaataagtta actgatttaa
     2581 aaggaaaaaa tatcgcaacc ttaagtccta actctgctag cggctacatc tatcctgtcg
     2641 ctgaattgaa agatgctggg attgatccta ctgcagatac aaagatgacc actgtgaatg
     2701 atattccgag tgagattacc gcagtgttga acaagcaaat ggatgcggcg tttgtttttg
     2761 aaggcgcgcg aaatgttttt gcttcgaatt tcccagataa tgatttattt aaggatttaa
     2821 aagtcctgta cctgacaaaa ggcgatattc cgaatgacgc aatcgctgta cagcctgaca
     2881 tgtcaaaaga tttaaaagcg aaaattaaag agaccttctt aaatatgaag gatgataaag
     2941 atggcaaaga agcaatggct ttgtgggggc atcagggcta tgaagaagct gctgattctg
     3001 cctatgacac gatcagagac tacacgaaaa aagcagcaga ataaaacatc agtaagtgtc
     3061 agcaagcttt tttttgctta cacttaaaaa aatggagaag gataatgatt atttttgaca
     3121 atgtttcgaa ggtctatccc aatggcgttg ttggcttgaa ggatattgac ttaacaattg
     3181 aagatggaga atttgtttcc atcatagggt tgagtggtgc tggaaagagc actctgctgc
     3241 gcagtatcaa tcgcttggca gaaaccacca aaggagatat tcgcattaat ggaacctcta
     3301 ttacaaaagc gaataaaaaa gagctgcgac agattcgccg ccagattggt ctaatctcgc
     3361 aaagcttcaa tctggtaaag cgtagtacgg ttcagaaaaa tgtgctatct ggacgtttgg
     3421 gctattactc cacttggaaa agtattttag gtctttttac gaaggaagac taccagcaga
     3481 caaaggaagc actggaaaaa gttggtttgt ctgataaatt gcagacacgc agtgatgagc
     3541 tcagtggtgg gcaacaacag cgagtatcca ttgcgcgagc actcgtgcag caagccccca
     3601 ttattttagc ggatgaaccc gttgcatcat tagatccaat cacgactcaa aaggttatga
     3661 tggacctaaa aaatatcaat caaacgatgg ataaaacagt cattgtcaat ctgcattcag
     3721 tccctctggc tcgtgagttt tctacgcgtg tgctcgcgtt aaaagctgct caggttgtct
     3781 ttgatggtcg tccagacgac ttaaccgatg aacgcttaga gcaaatttat ggcaatgcaa
     3841 tctttgaaga aaaggcaggc gaaatcgatg agcttgaaag aaaccgttca ctttaaatgg
     3901 tataaacacc tgcttattct tctgttctta attgtttgtt ttcaaggaag tgcctggatc
     3961 acgtcagctg atttttctca ggtttttcaa aactccaatc aaatgactgt ctttttatca
     4021 cgcttcattc atccagactt tagctattta cctaaattag tcgagcctat ggtgaaaaca
     4081 cttcaaatgt ctttgcttgg aacggtcatt ggcttaattt tagcgatccc tgttagtttt
     4141 ttagcgacca ctgtagtgac agaaaaccgt cttctttcta ccatctttcg ttttctttta
     4201 ggtttagtac ggaccatccc taccctgctt ttagccgcgc tttttgttgc tgtgtttgga
     4261 attggtgaag cgactggcgt gttgactatc gctgtcttta cttttggtat ggtgtcacaa
     4321 ttaatgtttc aagcaattga aaccattgac tttggcccga ttgaagccgc tgcggctgtt
     4381 ggagcaaata aaatgcaaat cgctatttgg tcgatcgctc cacaagtttt gagtcagttt
     4441 gcgagctatg ctttttacgc gtttgaggtg aatgttcgtg cttctactgt ccttggatat
     4501 gtcggagctg gtggtattgg cgttattcta aattcctcac ttgcgctttt gaattatgaa
     4561 cgagtttcaa tcattattct aacgatccta gtaactgtcg cgatcgttga taaattaagt
     4621 gaacgtgtca ggaggtccct gttatgatgc ttcgtgaaat gaacagaaga acccttttat
     4681 cattagttgc tttagtgatt ctcgttattt tgtcggccgc tactctggat tactctggat
     4741 taagcacctt ctctccttcc atgggaatgg acgttttgag agggttaggt cagcctgatt
     4801 ggcagtttct atatgatggc agcggcgagg atttgattag tttgctatta ttaaccattg
     4861 gaatcgcctg tttagggaca atgatcgcta cggtattagc gattcccatt accttgatca
     4921 gtgcggttaa cctctggcaa gcacatccat gggtaacaaa aattggcaag cttatctgta
     4981 atgttttacg agcttttcct gaactagttt ttgcaattat ttttgtgaaa gtcgtcggac
     5041 ctggcccctt tgctggtgtt atggcgattg gcgtccatca gatcggaatg cttggcaaac
     5101 tttttacaga agaaatggaa gcgatggatg agcgacttgt tgaagaaatg catgcggtag
     5161 gagcaaattt ttggcaaacg attttctttg ttcgcatccc ctatttgatg ccgatttatt
     5221 gttctttagc attaaatcat tttgaaatag cggttcgtag tgcggctacc ttaggcttag
     5281 ttggcgctgg cggaatcggt gctccattga tattcgcgat tcaaactcgg tcttggagca
     5341 aagtgagtat tattttgatt ggcgtagtcg taaccgtgtt tattttagat caaataaccg
     5401 gaattataag aaagagattg agataagaat gaatatattg catatatcag atatacactt
     5461 tcgcagagag tatgaggctt gtgaagaagg ctataaggga atgctggcta cgatgcagaa
     5521 tccccttatc cctctggagc aatgcattca tcatctcctg cagcaaacac ccttggacct
     5581 tgtgattatc agcggagatt taaccgaaga tggcgaaata gacgattatc gatacttgaa
     5641 gacttggctg gaaaatgcgc taggagaaac gacgattctt gttactctag gcaatcacga
     5701 tatcaaagaa catttttggg taggctggtg cgatgaagcc gcctcttctg ccccgtacaa
     5761 ccagatagtc aaatatcctg agtttacagt gatttccttt gataattcaa gctatggata
     5821 cgcagatggt atagtggacg atcagcaatt tcaatggctg aaaaaagcct tagagcaaga
     5881 aaaagaccaa ccgattttct tggtcaccca tcatcatcta ctgtctcacc aaagcagtat
     5941 accaaaatgg cctggtaccg aacgtttctt gaagctaatc gcaccttacg atattcgctg
     6001 tatcctaaac ggtcataccc atcacacatt tactgatgaa attaatggga tcccctattt
     6061 tactgtatcg agtatgtcct ttgttggtga agatgaaggc gatggcttcg tacgctttga
     6121 agaacgtcat gggtataacc tttatcatct cgatcaagga aggattgttc gccagacaac
     6181 agaaaacttt attccaggca acattttaaa aacacttcaa atgaaggatt aaggcattat
     6241 aaatcaaaaa aagagaccga acagctgaat acgcttcggt ttttctattt tgagtcagct
     6301 aaaggagcac gcagaatgaa cattacgttt ttagagacaa gtgatatgca tggctatgtt
     6361 tcaccaacag actattccgg cagaaccgat ctggccttag gaacggctaa agtatcgtcg
     6421 aaactgaagg aattacgggc aaaagcagat ggaccggtaa ttacgatcga aaatggtgat
     6481 ttcatccaag ggtctccttt gagttattat cttgctaaag aatatggttc agccaaagag
     6541 cttacagact tgattaacca aatgagctat gatgttcaag tgttgggaaa tcatgagttt
     6601 aactatggtg tggattatct cgaggaagcg attaagaatt atcaagcgcc tatattagga
     6661 gccaatatgg tgaacaaaaa tgaccaacca tactttggaa acgcctataa gattatcgaa
     6721 aaggtgggtg taaaaattgc tatcttggga ttaacgacac aatacattcc tcactgggaa
     6781 aagccagaaa ccttagcagg aattacgttt aagagtatcg tcgaaacagc aaaagaatat
     6841 gttcctctat taaggaaaca agcagacttg gtaatcgtta gttaccacgg cggatttgaa
     6901 aaagacttgt taaccggtga ggacacagaa gcgctaactg gagagaatga aggctacgag
     6961 ctattgcagc aggttgaagg cattgacgcc cttttcaccg gtcatcagca ccggaaaatt
     7021 gctgaaacgg ttcatggagt tcccgttgtt caaccaggct atcgtggcga gttcatcggt
     7081 gaaattcgtc ttaccgtcga gaaaaaagag gggcaagtgg ttgttacaga tcaccaggtt
     7141 gctttacact cagttgaaaa atcagagcct gatccagaaa ttcttgcagc gatcgtaccg
     7201 gtagaagaaa aactagagaa atggttggat caacccttag gtaaagtgaa cggaaatatg
     7261 cgtattaatg atccgatgca ggctcgtctt gaggaacatc cctatgtaga gtttattaat
     7321 cgtgtacaat tatttgccag cggctcagag atttctggaa ctgcgttatt caataatgaa
     7381 ggaaaaggct ttggtgagac gatcacgatg cgggacgtca tcaccaacta tatttatccg
     7441 aatactctgg cagtgattca aataaatggt gcagatttga gagcggcgtt ggagcagacc
     7501 gcaaattatt tagctgtaga aaataaccaa atcgtattca atccagcctt tattcagcct
     7561 aagccccagt actacaatta tgacatgtat gaagggattc agtacactat tgatatgaaa
     7621 cagcctgttg gacaacggat taccgaactt cgttttaaag gtcaccccgt tcttccgcaa
     7681 caaatgctgg aagtggtgac aaatcaatat cgggcaatcg gcggaggaaa ttatgcgatg
     7741 tttggtgcgg agaaaattgt ccgagaaatc caaatcgaca tgaccgaatt aattgccgac
     7801 tatttgaata ttcacccacg catcgaagca aaagtgaatc ataattttca agtgattttg
     7861 tagtatataa ataaaaaatt caaaaaggtg tgagcagttt tttgcccaca cctttgttat
     7921 gccaaattgt taggctgtct gatttccatc cagccattct ttagccagcg atctacctca
     7981 tcaaaacaaa aaattttcct ctgatggttc cttaaataag actattttga tcctttttcc
     8041 atgaataaga ttttgcatca gacaatactt catttctgaa aaagttgcgg caccaatata
     8101 gcctaatacc cctttccgat cttgattaaa tacaaaaaat aaatccgctg ctgcgatatt
     8161 taaaaaaaag tcgtcaagat ttctggatac tctttgtcta ggatcggaca tgagcgagga
     8221 taatcaatta attcaatgcc ttttttactg aaatcttttt ccatatctcg atattcttct
     8281 tggaaaacaa tacttccaga aataacagct ttcacaaaat tggcctccat ttttttattt
     8341 ttcagacact ccaccatacc ggatacctct caaagaaaag acatagcaaa aatcaatagc
     8401 agctatctct ccacggtttt ttactggtaa ttttattttt cttttggaaa ttgtatcagg
     8461 aaggtcgttc cttcattttt tcggctggtc acttcaattg aaccgtggtg caggcgcact
     8521 agttccttca cgattgataa tccaagacct gactcgccta tctttgtatt tttacttgac
     8581 ggatcggctt tataatagcg atcccaaatg tttttttgtt cctcttcaat catgccgatg
     8641 ccattgtcct cgacagtaat aaatacaggc tctttgtcaa atgatgttgg taaagagaaa
     8701 tcttagaata atttggacag aacagaaaga agaaactctc tttctgttct gtttatttgg
     8761 ttaaaaatgt tttgccatga cgaatcatga tccgtagttt gaaattgtaa aagctgcgaa
     8821 agccgtacgc attgcgtttt aatactttga tgtggttgtt taaacattcc aatggtccat
     8881 ttgaatagct gtagtgaagc gcattttgga tctgtggcag aaacttttta aacgttcgta
     8941 aagtggttgt ataggtttca ggaagaccgc tgacttctct gtttaaacag tcctcaaata
     9001 atgactgatc tcttttcttt accgcataaa gaatgtcttg gtataactga tagccttggc
     9061 gcaggttggg acaagcagat aacagtcgat cgacaatctc actttcagtc aaataatctt
     9121 taaaactggc acgccaaacc cttttttcgt agtttaactt tgcttcttct ttttgtagga
     9181 gtttccaata gcgtttcaat tttttcccta accctcgttg agagtgggaa gttcctttaa
     9241 gccgtgccgt ggtttctttc actcgatgat tcaagaaggt tctgccaata tgttggacga
     9301 tgtggaaacg gtcgatgatc aactgagcat tcgggaaaag ctttttcacc aatgaaacat
     9361 aaggcgcata catatcaata acaatccatt gaacggcttc acgagtcgct aatgaaaacc
     9421 gagaaaaata gcattctaaa taaggcaagc gtcgattttc gacaatatcc aataatgcat
     9481 ggctttgtcc gtccatcatg ataaaactca ttgcactggc aacacttcga accgatttga
     9541 attcatcaaa gcataagacc tttggcaaag cctgtttgaa aggattcaat gggcggtaga
     9601 atcgcttcat gacacgatag accgaagaag tggaaatatt tttctgacga gcgatttccg
     9661 tcatggaagt attctctttt aagcgagcaa tgacagacca acgaactttt tgactaatga
     9721 aacagtgttt ttcagcaaca gaggtatccg ctacgaatgt tctttggcaa gacttacatt
     9781 taaatcgttg tttcttcaac tccagataag tgcgatactc agacgcatca ttcagtaaca
     9841 accgaacggt tgtcgtcccc caacgaatga tcctagaggg gacgacacaa agacaatggg
     9901 aacactcttc tggcttgtac agaagagttc ctttgtaaat catggatttg agtcaatatc
     9961 ttggacacat tttagtagag acggttaagc cattttttct tttgctaatt cttcaaattc
    10021 ctgtggggtt agatagtgaa tcgagctatg gattcgattt cggttataaa atccttcaat
    10081 gtagctaaat agcgctcgat ttgcttcttc aaaatctgag tagctagtcg tgtagacttc
    10141 ttcttttttc aatgaggcat ggaaagattc gattccagca ttatcataag gtgttccttt
    10201 tctactataa gaatgcctta ttttgttggt tttaagccat tgttccactt ctcttgctgt
    10261 gtattggctg cccaagtcag tgtgtagaat cattccttct ggaatgtgat aatgtatttt
    10321 tgctttattc aatgtttgaa tgacacaatc cacagtcatt cgttttgaaa atgtataact
    10381 aataattttt ttcgtgtgta aatccatgat tgaagataag taacaccaac catttttctt
    10441 agtaggaatg tacgtaatgt cagctgccca tttctcacag atcgtttcag tagaaaagtc
    10501 ctgatttaag agattctctt ttgaaatgat cggtttatta gacctttgag gtctatattt
    10561 tttaactaca atcgacctta aatttaattg tttcattagc ttttggacat gtttaagaga
    10621 tactgaaatc ccttctttta ataaaacttg atggatcttt gtggcaccat agcgttgttt
    10681 attcgtaaaa aaaattgttg aaatcttctt tttcaactta ttatttctga tttctgtagc
    10741 tgtcaacggt ttattcttat aaaaataata gacacttcta gggatttcta ataaccgaca
    10801 taacaaagaa acagtgtaat ccttacacca tttttcaata aattgaacaa gcgaatttag
    10861 gttttccgag agaatatggc tgcggctttt tttaagattt caagttcctc atttaaacga
    10921 gcattttctt ttctcagttc agctacttct tttccagtca gtcctgtgga ctgatcaggt
    10981 aaatataaat tcttccattt gtaaatcgtt gcttcagata agccatattc tttcgctaac
    11041 cctcgaacag aacgtccagt ttgattcagt tcaacaatca tttgtttaaa attttcttca
    11101 tatcgggtca taaaaattca tcctctcgta gataagttta atttattctt gtctctacga
    11161 aaagctgtct aagatttgat actaacacca agttatcttt agaaccattt cagatacata
    11221 tgaaacaatt acatatgatt ttttcataaa aaaacagtac tgtctagtag tataaaatat
    11281 acaaatttct taaaaatttt ttcactaaaa tcactacctg aaacagtcta aaacacttat
    11341 atatcaacgt ttaatgaaac tatctccgtt tcatttcaga tacaaataaa tatagtcggg
    11401 ctccaaatcc gaaaaaaaat acccccagta gcttatccta agctactgga gatgtataag
    11461 tacggtcata taacaacggg gtagggtaaa taaatgaaaa agatggaaga atcattattc
    11521 aataactttt ttaaatactt cgttgtaatc agttacctgt ccgttcttaa ataccacaga
    11581 ataatctttt ttcccatttt caagtaaccg aagtggaatg tctttaccaa cttgctctgt
    11641 cactgcatta ctgatacctg ttagattagc taataaatct gataaagatt gagcatctgt
    11701 agaaatctct gtatcagtat ttatcgtgat tcctttatct tcatttacaa gcttccaagt
    11761 aggtggtata gctgtgtatg tttcgatgaa tgaatcaatt ctttcatcta tcgtcttccc
    11821 agtatctact tctgtctcat tactcttaga tgaatcgatt ctttcatcca tcgtctgctc
    11881 cgtaactgct tctgtctcat tattctcacc ggaaactctc ttcacaccca aacttatata
    11941 ttgtccatct ttagtgtgca tagttaaaat tcccacgctt ttactaataa attcactata
    12001 accagttctt tcaatagaga cttcaatgta tttcacacta tcatactcaa aagaaaaata
    12061 gacatgtaaa agcattttgt tgtttacatc tacataataa tcctttgact ctacttgaga
    12121 ccttcctata cggaatacag ctttactgtc tgatatctct ataccagcat ccttattatt
    12181 aatctgccaa tctccaagta gctcttctgg caagctagta gtttcttgtg aacactttac
    12241 cacttcactg gtagaggtcg aaacattcac ctccgcactg ttagaagaat tttccaagga
    12301 atcaggagcc ttagcacaac caacaagtct ttatatattg tgcagccgat attttcttca
    12361 ttcagtacac ccttgaaata tgcagtgtta gataaagcag ttcgtcctga tttgctgagg
    12421 cacccatctc ttcttgaacg tactccttga ttttcaaggc cgcccgatac tctttcggaa
    12481 aacgctgctt cactgaagcc agcaaaaaat catccttctc cggcaactct tccttcttaa
    12541 tcattcgggc aataaaaaac tgtaaatgcg tcacaaatct taagtaaagc atcgaatctt
    12601 tatcaacctt tttttcggga aacagatatc ctagcatagc caagatatcc tttagtgctc
    12661 ttaccgagag catggtttct tccatatttg cttgttcact ttgggcattt acaatgtgaa
    12721 acgcaatgtt tccagcctcc tcttctggca actgaacatt catttttttg ttgatcaatt
    12781 ggatagcata gcagccgatc tcaaattctt ttgggtaata cttttgaatt tcaatcagca
    12841 ggcgattttg aaaaacaatg cctttttgac tgcgttcaat ggcatgcttc aagtgatcaa
    12901 ccaaggtaaa aaatagactt ttattcagct taaagtcaaa cttggcgttg gcataatcga
    12961 taattcgctt gacgcaaata attagatcat ccggagcagc ctcaaacagt ttaatgtaat
    13021 ccttttttag agcatcagaa agtgaatcta atttaaatac tttttggatt ttgtcagccg
    13081 gaaccaaatc gcctttcttt agttgaaatc caatcccttt ccccatcaaa attacttctt
    13141 tgccttgctt atctaagcaa agaattaaac tgttgtttaa cgttttaatt actctcatta
    13201 gattcaccgt tctctctaag ctaagccatt tcttgcgatt actttttgat accaaaagaa
    13261 gctttctttt tttattcgtt ttaattcttt aagattctca tcggttcggt caacatatat
    13321 aaaaccataa cgcttattga agccttgatg ggtactaaca acatcaatcg ctgaccaagg
    13381 taaataacca aaaacatcta caccatctgt taaagctgct tgaatagcca gaatatgttt
    13441 ggctagataa tcaattcgat cctggtcatt aattcgtcta tcttcctcaa ctatgtcggg
    13501 tgccccatag ccattttcag taattaaaat aggtaaatca tagcgatcgt acaatttcct
    13561 caatgttaat cgtagtccag tagggtcaac tacccagcca tatggcgttt tatctacata
    13621 aggattttca gctgcccggt agacaccttc ttctcccaac atgatctgtt gatcccccgc
    13681 tctagcggaa acatctgatc cgtcattttt gctggcagcg atggtggcag ttgaataata
    13741 attaatcgca ataaaatcgg gtttaccgga ggataaaatt gcctgatcct ctgcctcaat
    13801 tttaggatat aatccacgat cattcaaata gttttcaaac aaataattgt attttccccg
    13861 aactgctaca tctaagaaag accagcctct caatgtttcc caattatggg ctgcaattgc
    13921 atcttctgga ctggaggtag cttgatacat agccgttaaa ttgattgctg gaccgatttt
    13981 tcctttaaga ttcaactgat gatacaagtg aattactcta gcttgagcta ataaaacatg
    14041 gtgattaatt tgaaagagtt ctttttttga aggcagctct ccacttggtg gcaaaccaat
    14101 cgctccagga tgaaggatca tcgtgttttg ctcattaatt gtcagccaat agttcacctt
    14161 gtcaccatac tcagtaagca atacctgtac atagtccaca aaataatcga tagttgctcg
    14221 atttaaccaa ccgccctgct cctctagaaa ataaggtaaa tcgaaatggt acatggtgac
    14281 aatcggttcg attccctgat tcaggcattc atcaattact tgatgataaa aagaaattcc
    14341 cttttgattg gttttattat tttcaatatc cataattcgc gtccaagcga tggaaaagcg
    14401 aaaagctttt aagcctaatt ctttaaacag ctgtatatct tctttatagt gatggtaaaa
    14461 atccgaggca acttcaaaat tagctacccc ttctgtatgc tgatacttgt caataataga
    14521 cggttgtttc ccatcctcct gataggcacc ctctgcctgg taggcactaa tggaggcacc
    14581 ccataaaaac ttctctggaa atgctgaaag ctgtttgtat tgcacaaaaa tcctctcctt
    14641 aactaatttg catcaatggt tcgtgttcct ttaagcttcc gcttgcttca ctaattcctg
    14701 cgtaattttc actgttggtc actaccacaa tcactgtatc atcgtagcca gcgtttctaa
    14761 tggcagcgaa atcggcgttg attaataatt gtcctgctga cacctgatct cctgctttta
    14821 caaatacttc aaagggttcc ccttttaaat tcacggtgtc gatccccaca tggatcaata
    14881 attcaatacc ttctttagaa cgtagaccaa tcgcatgttt agattctaaa atagtaatga
    14941 cttctccctc aacaggtgaa taaatgctgt tttcttctgg atgaatggct acgccctttc
    15001 ccaatagtcc cttagaaaag acagcatcgt tcacttcaga aataggacac acggttcctt
    15061 ttaccggatt ttcaacaatg actgcttcgg ctattgccgt ttgctctgat tcatcagaag
    15121 tatcgtcaaa tccaattaga taagcaatga taaaggttgc aacaaaggcg attacacacg
    15181 taataattgc gtgaacaata ttcattggat tttctccaat aaaggctggt aaggctgcta
    15241 agccagggga aacaaaggca tatctgacta aaccgctcaa gccagcatac aaaccagcaa
    15301 ttgcaccacc aatcatggaa gcaactaatg gttttttcag cttcaaggtt actccataga
    15361 gtgaaggctc agtaattccc attaaagcag tgatcccagt ggacacagct agctgcttca
    15421 actctttgtt tttagttttc gcggctacag caaaggtagc acctgattga gcaatattag
    15481 aagccagcat tcctggccca ttgatcattt cagaacccgt actgctcaat tgcatagtag
    15541 cgattggcgt cattgcccaa gctgtacccg taaccaccaa aaatggctgc aaaccaccca
    15601 tcaaaaatgg aattaaccaa gctgctttgc cgttaatcca ttcagccccc attgctataa
    15661 gatcgttcag caacgttcca aacggtccaa tgacaaccaa cgctaaaggc cccataatta
    15721 aaaataccag catcggctta gtaaagaatt taataaacga aggcgaaatt cgatccgcaa
    15781 agggctctac ataggacatg atccaaacag taaagataat cggtaaaact gatcccgcat
    15841 aatctgcagc taataccgga attcctagaa aagaaacggc atcgccagta gaaaaaagct
    15901 gtgaaatatt tggatgaagc aaaatgccag caacagtaat cgccaaaatt gggttgacat
    15961 caaactttat ggctgcccca taggctaata gtactggcat aaaataaaag gctgcatcag
    16021 caatagtatt caaaatgatg taagtttgac tactgtctga tagtacacca gtcaaagtca
    16081 agacggccaa aatggctttt accatcccgg cacctgttat agctggaatc atcggtgtaa
    16141 aggtggtaga aatgacacta atcaatcttg aaataatact ttcttgattg tctgaagagg
    16201 ggcccttttt aattgaagtt cccacttcct tttgaatttc cttgaaggct gtttggactt
    16261 cattgccaat caccacttgg tattgtccac cgctatccac cacactaatt acaccaagtg
    16321 ttttttctaa ggctttcgta tcggctttcc ttttatcttt gagttcaaaa cgcagtctgg
    16381 tggcacaatg ggttaagctg accacatttt cttttccccc aacctgttgc aatacatttc
    16441 ttcctacttc tctgtaatcc attattctct ctccttaaag cagtaaaaaa gaccaagtca
    16501 aaccacgccc caatcaacat tgaagtgtta gtttgtcttg gtcttgcctg cataatcagt
    16561 aacatgccaa taacgttatt ttgctgtaat ccaataatag cacattatga tagcgcaatc
    16621 aacagggaat ttaatttttt atcttttcgt ttgaccgtat agggtaatat aacagttaga
    16681 tcacatcaac tagggtatat ctgcgtatac ttactgctaa aataagtata tctaatatta
    16741 actataccag taaaaccatt cctacataac cagcgggaaa ttcccaaaat cgtgaaagca
    16801 tcaaaaatgc atataacgga tcacacaact tcaacaattc tgctcttggg aaaaattgat
    16861 gaatttggtg agtaaaggat ggaataaaca gcattccaac aatataggca acaatagtga
    16921 tacttgtttt tttggtaaaa atcagtaagc aatagccaat ttcaatcatt ccgagatata
    16981 aaggtatcga tagaatgatt tgggctagta ttcttaaaaa ttaactagca aatgtttaaa
    17041 ctgatttatt tctaatctac atgtagtaag tatttcaatt ccaccaatta tcaataaaaa
    17101 taccaaacat atccataata attttttctt tttcatttct tttatattgt tataacagtg
    17161 aataacataa aaattcccga caatcattgt aatatttttt tgtcacctgt attagtattt
    17221 aatttatagg aaactataaa aactccctag tgaatttaca cctttgggag ttcctgtttg
    17281 gacggtatgc ataatacatt taaatcaatt taacattaac acctcagcat atggtatctc
    17341 cacatatata cggtctttct ttggatagta ctcaatattt atgttgatag cacttccatt
    17401 gtctaatata gctttagccc ggtatgtgtt atctccattt tcatgagtaa tcgtcacatc
    17461 atcacatgat cgatttaagt tgtactgttc ttgtaaaatc tgtgttacca atggtttcga
    17521 tgacttctct aatccagatg tacctgtcat ttttgaaaaa atgataccta taatagccaa
    17581 gacaacgata actataatga taaacttctt gttcatattt actttattca actttttatc
    17641 tcctatctcc aaaataattt gctcttatcc ctcttatcag tacattgaca tccctaaaag
    17701 tacaccaaag attgctccag ctacccctgc tatcatcaaa atcgtaccca tttgttcatc
    17761 tttatctcga tataagtagc ccataataac agcaacagca ccaaatacaa caggaataaa
    17821 tgctaacgct actaccatag aaatccaacc aataatcaaa tacagcttcc ctgtctcttg
    17881 tccatgtacg atttgttcct tcatttcatt aattgtctgc tcagtacttt tctttactgc
    17941 gtctgctcca gttgtctcat ctgtttcttg tagtgctccg caaaactggc aatacttact
    18001 ttcatctgtt atttctttgc cacattttct acaatacatg tcttctcctc ctaaaaacat
    18061 tcaattgttt attagttaac tgtttacttt attaaataca tcagaaaaca gctcattcat
    18121 tggtacactt aatatctcag aaagcatctt catttgatag ggtttaggaa tcgttctccc
    18181 tgtttgccac gaacttacac attgctgtgt aacattcatt tttttgctaa ctccgtttga
    18241 gaaagtcctt tttcttttct gtatcggctg agattactta cttttttcat gattctcccc
    18301 tcctgtttta ttatatacaa caatatgatg tatttcaact cataaaatat aaaaaaactt
    18361 caaataccat tacaaataca acaacttgtt gtactatact gagatggggg tgtattaatg
    18421 aaacagaaac aatatgcaaa ggtcattaga gaaaagcgaa aagctctcgg gtggacacaa
    18481 aaagaattag ctgaaaaaat cttctctaca caacaggcag tagcaagatg ggaaaattct
    18541 gtaacagagc ctaacctcga tagcttaacc gctctttcta gagccctagg aacccctgta
    18601 agccattttc tagacaatgt tgtcgtagat tatgaggaag agtttttggc tctctatcgt
    18661 tctcttagca ctgaagatgc agttcgaaca attgactata tgaagctatt aaaaaggcaa
    18721 gaaaatgaac gcaatcagct attgaaagat tgaaaaataa ataacccacc gaactttaac
    18781 ggtgggtgta ttgagatgaa ataagattaa gagctatgga taacctgtct agtttaatac
    18841 aattgggtct tttctcttcc ttactctccg tccatcatct cttgttacac ttgtaaattg
    18901 ataaagagga actaattcaa ctcctgataa tatcaattct tttattactt catctatccc
    18961 tgctcctttt gctaggtaga ctaaaaaact actacttgct ttcacattgt atagtctctt
    19021 aatatcctta gaagctcgtt caagagtgaa tccttgttta acaaagtagc ctctgttttc
    19081 ttttaaagca ttttccacgc tgttattccc aacattacgt agacgttcac aaacagtgtt
    19141 agtaagttct ttctctgtca ttagatatgt tccttgccac gataagccct gtaaaacttc
    19201 atgtgcttca tctaaaatca attgtttttc cttgctaagt tctgatcggg aattttgagg
    19261 aaatactctt ttagcctctt tttcgttaaa acatatctta acccattcat aagaaaaata
    19321 ttgatatgta aaatgaaatt tttccagaag tggaaggata tcttcattca atttttgaat
    19381 cacagaagtt gcattaaaaa cgtctaatcg atagacattg cttctcttat gattaaagtt
    19441 tcctaacgct ttctcttcct ttaacctatt taggtattcg agcatcttca aaggaacatc
    19501 ttcatcatct aattttttta tcaatcctat aaaagtcata agtgatagta acttattaca
    19561 tttatctatg tcataagttt taccatagta aaaactcatt tttttagcta attgttcccc
    19621 cgacaaaata caagtcacac tttccttact atcatcaaaa aaattaacat cagaaagcaa
    19681 gacatcatag acacgtcgca tttcctctag ataattcctt attgtcctga aaagtttgtc
    19741 tttcattgat tcaagagtgt caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg
    19801 tgtaggatac aagtctaggt tctctaatag ccaattaaat gtttctaccc gactgtcttt
    19861 ctttaaaatt agcatcacaa ctccaataaa attttcactg atatcacaat tactggaatg
    19921 acaataaaaa atggaatgcc cagttttact ggtaaaaata ctagcagagg gattatgatc
    19981 gttgtgaaac agacatctta agtttttact tgacttaagt aatttattca tatcaatggt
    20041 taacaatctt tcataaatct cattaaaaga catgtcggag gaatcaaaca ggcagtcttt
    20101 aaaccactgt ttcatttctt ctttgtcgtc attttttatc aacttaacaa aatcggtttc
    20161 attgactagt tcatactctc tccctgaatc actttgacaa tttttagaac atgtcatggt
    20221 aaaatcaatc ggaagctcag taatatctaa catgttgtct tcattaatta ttatcactgc
    20281 atctgactta tatcctccaa aaaacattct attcgaagca tttacattgt catcacaccc
    20341 ggggatgttc tttttcaagt attcgtaaac agcaaccatt ttaccatagt cagtaattgc
    20401 ttcttttaat agaaagacaa tcttgtattt ttctagattt tcagagtacc gaatactttt
    20461 ttgtatcgca aacgcagaat tatgaactaa attgatagat aaaacctttt ctatgcttaa
    20521 gtatctacta tcatctttac tcaaatctac taccttcccc ttctcatctt taacagtgtt
    20581 atcgacatcc agaataatta ctctggtttc cacaaaactc tccttgtcat tgcctttatt
    20641 ctttgtcttg cttggaataa atgattgtga tgaatttagt atctctacaa actcatctct
    20701 tgtaacttct ctatagttat ctaaacacct atctcttaca tcagtttttt ctttttttgt
    20761 aactggcttc tctaataatt tttctttatc tacataaatt ggaatattaa tcattgatgt
    20821 ttccatttgt gtttcctcct tataaaattc tgttaaagac taaaacatac agataataaa
    20881 aacaaactct ttattactat atgttttagt cttatttgtt tactcaacct ttataccgtt
    20941 ccatgaaact atcaatatca gattttttaa atctaatgac cgtatcaatt tttataacag
    21001 gtaacccgta ttgagaaaca tattttctaa tcgttcctac tgatacacct agatattcac
    21061 ttgcctgctg atagtccata tactctagag tgactccaga aataatgtct tctagcatag
    21121 gctttagcac tgtaattatc tctttcactt gttgttcaac ttgtatagaa acaatgctat
    21181 caatgatttg tagagacata tttccccctc ctttcgtgat tgcttgaaca aattttctaa
    21241 gaattatctt cgtatttttt gctcaaaata aaagtatttt gttattaacc gattaatcaa
    21301 acaaaaaatg attaccagtt catcgacata cacataatac ctcgataaaa aagaggtgtc
    21361 aatatctttg taaaatttat ttacaacacc cctttttcga ggtatactaa ttttaggagg
    21421 tgtggtcaat atgataaaac gtccaccaat aaattattta gaacgaaaaa agatactcgg
    21481 aacaaaaata aaagctataa gaaagagtaa aaaattaaca caaccagcat ttggtcttat
    21541 gattaacaac ggtcaattaa ttgacaaaaa aactatctac gaatgggaga agggaaccta
    21601 tttaccaata ccagagcgat tatcccgaat tgctgatttg ggaaatatga gtatagagga
    21661 gttagtttgt ggcaatgtag aagaatatat tttgggaatt attctttata gagatagcat
    21721 tgtactagat ggtataacat ttccagataa aaacctgttc cagcatcttc gtcaacagtt
    21781 cccaccagta cactctaatt tagatacatg gctggataga tattccaaat tagaaccaga
    21841 gatgcaagaa tttattgcta acaagacttg taataaagtt aaaaatgaaa aaattagtct
    21901 tttcaatatc ttaaaaatag aagaattatt catcaatgct attgtagaag aatttgacaa
    21961 taacattctt ttcctcacta gcagtataga agaactacta gaaagaatgg tagatgaatg
    22021 gctacctatt caattgaaag acatgtctta tcccgaagaa gctgtgagag aaattactga
    22081 taatataaac aagctagaac aaacgatttc atcaattggg aaaaaataca ctaagaaaaa
    22141 aatgaaggga ggtgatacca tctagtggta agtactcctt gtaaactaag aggagatgat
    22201 ttcatggcaa aaatatcaaa gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa
    22261 ggacacattg ccaccgatcc acgaactggt gaaaaaataa atactacgag aagaggtttt
    22321 agtagcaaac aagaagctca aaaagattat gacgagtaca gacatcaaat attatacggt
    22381 gttaaaaaga aagcacctga tatgacattt gaagacctgt ataatgaatg gataactcat
    22441 cagcgtacca gtgttaaagc ttcaacaatc gcaatctcag taagatacgc aaataatcaa
    22501 atacttccag catttggtaa gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa
    22561 gtggtagatg aatggcacag taaatatgaa agttacgatt atatgagaaa acagactgca
    22621 caaattttac gctacggggt tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca
    22681 cttcttccac gaaaaaaaga gtatgagaaa aatcgtaaat tttactcaaa agaggagctt
    22741 aataatttac tggatgcttt taaagatttt ggtaacatga aacaatacgc cttcttcaga
    22801 ttattggcat acacaggtat gagaaagagt gaagtactcg ctttacagtg gaaagacata
    22861 gacacgttta ataaagaact acatgtcaat aaaactcttg ctgtagatga atttggtaaa
    22921 gttataattc aatctccgaa aacaagagct tctagacgag ttatctcttt agatactgag
    22981 actctttcta tcctcaacaa ctggaaatta cagcaaaaag aagagtattt aaaacttgga
    23041 tacaatacta gctctaaaga gcaacatgtt tttacaacag ttaaaaacac tctatacatt
    23101 ccaaacactg ttaatgattg gttaagatat attttgaaaa aatataactt gcctcgtatt
    23161 acacctcatg ggtttagaca tacacatgct agtttattat tagaagcagg agaatctgtc
    23221 aaggtagttc aacaacgatt agggcatgaa aatagtaaag tgacattaga catctatgca
    23281 catattacaa ataatgcacc taagaaaaca ggtcaagact ttgctgatat gatggctcat
    23341 cagtaaaaga gctggtcaaa atctggtcat ttctagtata caggcaaaac aaaaaagcta
    23401 gaacccttat atat
//
LOCUS       DAZKCH010000042        23169 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000042 DAZKCH010000000
VERSION     DAZKCH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.042"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..573
                     /locus_tag="ACG84X_001637"
     CDS             <1..573
                     /locus_tag="ACG84X_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127507.1"
                     /translation="SIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYLLSEKEQ
                     LLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFVVSESSV
                     KQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQNGLETEK
                     TKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            794..2557
                     /locus_tag="ACG84X_001638"
     CDS             794..2557
                     /locus_tag="ACG84X_001638"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFP9127508.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            2641..3099
                     /locus_tag="ACG84X_001639"
     CDS             2641..3099
                     /locus_tag="ACG84X_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFP9127509.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            3208..3891
                     /locus_tag="ACG84X_001640"
     CDS             3208..3891
                     /locus_tag="ACG84X_001640"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFP9127510.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            4038..4652
                     /locus_tag="ACG84X_001641"
     CDS             4038..4652
                     /locus_tag="ACG84X_001641"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFP9127511.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            4668..4874
                     /locus_tag="ACG84X_001642"
     CDS             4668..4874
                     /locus_tag="ACG84X_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127512.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     regulatory      5099..5265
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            5413..5970
                     /locus_tag="ACG84X_001643"
                     /pseudo
     CDS             5413..5970
                     /locus_tag="ACG84X_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            6028..8067
                     /locus_tag="ACG84X_001644"
     CDS             6028..8067
                     /locus_tag="ACG84X_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFP9127513.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFINNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(8176..9327)
                     /locus_tag="ACG84X_001645"
     CDS             complement(8176..9327)
                     /locus_tag="ACG84X_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFP9127514.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(9481..10011)
                     /locus_tag="ACG84X_001646"
     CDS             complement(9481..10011)
                     /locus_tag="ACG84X_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFP9127515.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(10110..10460)
                     /locus_tag="ACG84X_001647"
     CDS             complement(10110..10460)
                     /locus_tag="ACG84X_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFP9127516.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(10617..12146)
                     /gene="ahpF"
                     /locus_tag="ACG84X_001648"
     CDS             complement(10617..12146)
                     /gene="ahpF"
                     /locus_tag="ACG84X_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFP9127517.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(12156..12719)
                     /gene="ahpC"
                     /locus_tag="ACG84X_001649"
     CDS             complement(12156..12719)
                     /gene="ahpC"
                     /locus_tag="ACG84X_001649"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFP9127518.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(12863..13525)
                     /locus_tag="ACG84X_001650"
     CDS             complement(12863..13525)
                     /locus_tag="ACG84X_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9127519.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            13709..15355
                     /locus_tag="ACG84X_001651"
     CDS             13709..15355
                     /locus_tag="ACG84X_001651"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFP9127520.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            15346..16428
                     /gene="uxuA"
                     /locus_tag="ACG84X_001652"
     CDS             15346..16428
                     /gene="uxuA"
                     /locus_tag="ACG84X_001652"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFP9127521.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(16536..18089)
                     /locus_tag="ACG84X_001653"
                     /pseudo
     CDS             complement(16536..18089)
                     /locus_tag="ACG84X_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            18237..19378
                     /locus_tag="ACG84X_001654"
                     /pseudo
     CDS             18237..19378
                     /locus_tag="ACG84X_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(19504..20583)
                     /locus_tag="ACG84X_001655"
     CDS             complement(19504..20583)
                     /locus_tag="ACG84X_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9127522.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(20692..21132)
                     /locus_tag="ACG84X_001656"
     CDS             complement(20692..21132)
                     /locus_tag="ACG84X_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9127523.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(21189..21599)
                     /locus_tag="ACG84X_001657"
     CDS             complement(21189..21599)
                     /locus_tag="ACG84X_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFP9127524.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(21780..22214)
                     /locus_tag="ACG84X_001658"
     CDS             complement(21780..22214)
                     /locus_tag="ACG84X_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9127525.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(22314..23162)
                     /locus_tag="ACG84X_001659"
     CDS             complement(22314..23162)
                     /locus_tag="ACG84X_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9127526.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT         8017 a         4164 c         4305 g         6683 t
ORIGIN      
        1 agtatcgctg aaatcgacga tgcagaaaat tttattttca agcaatcctt tttacaattt
       61 gtccgtacgt tgtgggcaga tggacaagta tttttaccgg aaaggatcta tcttctatca
      121 gaaaaagaac aacttctgta cggaaaaatt gtagaaatat tggaagagtg gaaaaagaaa
      181 aatcaaatcc aactaagatg gaatgaaaat ttcattcgaa aattcgtcaa aagtctttct
      241 ttgatcaaca gtgaacaagc ggggagacag gaaatagaaa tttttgttgt ttcagaaagt
      301 tcagtcaaac aattttttta tcgaacccaa tttcatttgt atgcggaaga aggcatcgct
      361 gaaataaatc ctattttatt tcgttcatta gaagaattgc ctgatgaatg tctatgtgcg
      421 aaaaaaagag tggttttgtg cgatgctgct agctatcaaa atggattaga aactgaaaag
      481 acaaagatct atccaatctc attaaaaggt gcaaacatcc atttgtatca tattgctcag
      541 gaacttcacc tattaaaaaa acatatttct tgatgagacc ttaattagga gaccttctac
      601 aaagcttttt aattgtctgt agaaggtttt tatttgagtc ctgattcgtg cgaagatcta
      661 cttatataac aagctttctc tgaaattttt ttaaaatgct attgacttag agtcaactct
      721 aagtagtaga atagataaag tgtaacaaat ctattttcat taaaagaaga tagtacggag
      781 gagagaatgt attatgagta cagtattaca tgtattggat gcaatcaata gccccgcaga
      841 tgtcaaaaaa ttatctgttg aggaaatgaa acagttggca gaagagatgc gccaaaaaat
      901 cttgcaaaag gacagcgatg taggtgggca cgttggtccg aatctaggtg tagtagaatt
      961 aacgattgcg tttcattatg tatttgattc accaaaggat aaaatcgttt gggatgtttc
     1021 ccatcagtct tatggtcata agcttttaac tggtcgaaaa aatggttttg aaaaaggaca
     1081 ttaccgtgaa gtgagcggat attccaacca acatgaaagt aaacatgact attttacagt
     1141 ggggcacaca tctacatcta tcagcttagc aacaggttta gctaaagcga gagatctgaa
     1201 gaaagaatca ggaaatgtgg tagcatttat cggtgacggc tccctaagtg gtggcttagc
     1261 ttttgaagga ttgaacaatg gtggtgtttt acaatccaat ctaatcgtat tagtaaacga
     1321 taatgagatg tctattgatg agaatcatgg cagtttatat aaaaacttag ctgagcttcg
     1381 tcaaaccaac ggtaaaagca gcaataacct atttaaagca atgggatttg attatcgtta
     1441 cgtggataat ggaaacgatc tggaaacggt gatccgttta tttgaagaag taaaagatat
     1501 tgatcatccg attgtacttc acgtccatac ggaaaaaggt cgcggttatc agccggcaat
     1561 cgataataaa atgaaatatc attggcatgt accatttgat ctgtccaccg gggaggcaaa
     1621 gcaagtaact tctggagaaa catttaatat gatcatcatg gattatttgg ataagaaaat
     1681 gcaaacaagt acagctccta ttgccgcagt caatgcagcg ataccaggcg cctttggact
     1741 gaaaacattc caagaaaaac atccagatca ttattttgac gtggggatcg ctgaacagca
     1801 ctctatcact ttcgcttctg ctttggcttc tcagggagta cgtccagtcg tcttccaatc
     1861 aagtactttc ttgcaacggg catatgatca attatcacat gatttagcga tcaacgagaa
     1921 tccagtgatt attttagtcg gtggcggaac gatctcagct agtgaccgaa cacaccaagg
     1981 aacatttgac attccttact tatcaagtat cccgaacatc aaatatcttg ctccagcaac
     2041 aaaagaggat atgatctcta tgctagattg ggcgttcgaa caaacagcgc agcctgtagc
     2101 aatccgaatt cctacacatg gtgtagaaca tggtacagct atcgcaaatg attatagtat
     2161 tccagcctat caaacagtaa ataatggagg aaaagtagca attttagctt taggcggttt
     2221 tcttgaatta ggaaaagaaa cagtaaaagc ttttagaaaa aaaggaatcg aagcaacgtt
     2281 gatcaatcca ggaacgatca cagaaaatga cgtagaaaca ttagataaat taaaagaaac
     2341 acacgaatta gtcatcacat tagaagatgg tagtttgtca ggaggatttg gcgaaaatat
     2401 cagtcgttat tatggtgatt cttcaatgaa cgtattaaat tttggtgcag agaaagaatt
     2461 cacggatagc gttcctgtag ggcagcttta tgaacgttat catttaacac caaaacaaat
     2521 cgttgaagat agtctgcgtg tcttgaatat tcaataattc attatgctca ccatccagat
     2581 aattgtttat actagtatct ggatggtttt ttcattataa aaagcaaagg ggtggatgtt
     2641 atgtatcagc aagtagaaga atatgtcaaa aagttccaag aaaaatatcc tagttatcaa
     2701 tcagaaaaat taggtttctt ttcatttggg gatacagaaa aaatggcaga cgagttgagc
     2761 gaactagttg taaaaaagat aaagactggt acatcaagtg gttacgatct gtataaacaa
     2821 gagaatgagc ctttaccaaa agttggtcaa ttagacgtgg tcctgaatgg aaaaaatgaa
     2881 ccagtttgta tcatcaaaaa tataaatgtg accatcttgc cttttagtga agtcacgaaa
     2941 gagcatgctt ggaaagaagg agaaggggat cggacattag cttattggcg gaaagtccat
     3001 gctgagtttt ttaaacatgc ttataaagaa gcgttgaaca tagaatttac agaagagaag
     3061 ctggtcgtat acgaagaatt tgaagtaatt ttcttttagt aagaaaggtc tgctgaaaga
     3121 aatagctcat tattgtctcc tgaatagaaa agggttacat ttttatatga agctgtattt
     3181 ttatataaca ttactggagg agatattgtg gatacactgg aacaaatcaa aggcggagtc
     3241 gtcgtttctt gtcaagcttt ggaaaacgag ccgctacaca gttcttttat tatggggaga
     3301 atggctttgg ctgcaaaaga aggcggagca gttggtattc gagcaaatac gacagaagat
     3361 atcaatgaaa tcaagcgaat cgttgattta ccggtaatag ggattatcaa aagagattac
     3421 gatgggtcag aagtgtttat tactgcgaca gaaaaagaag tggaagaact tttggagacg
     3481 caagcagaaa tcattgcact ggatgcaact tctcgtaaac gtccgacaga aaaaacaact
     3541 gctgaacttg tccaaatgat tcacgaacac ggtcggttag ctatggcaga tatttcgact
     3601 tttgaggaag cgcttcaagc gcaagaagat ggttttgatc ttttgtctac gactttagca
     3661 ggctatacag aatattcacg aaagacgcag acacctgatt ttgatttatt gaatcaaatc
     3721 atagaacaag tcgatatccc agtaattatg gaaggacata ctgactctcc tgaacaagta
     3781 gagaaagcat atgaattagg tgctttttca gtcgtagttg gatctattat cacccgtccg
     3841 caattgatca ctaaaagata tgtcgaagcc gcaagtaaag caaataacta aaaaacacgc
     3901 acggcacaga ttcttgacaa aaaagaaaaa ttgatagata gtttaaagca gattctaaga
     3961 agatgaaaaa agcattactt ttcattttgt cttcaagatc tgctttttaa cgaattttat
     4021 agaaagaagg cgaaaccatg tttgaacgga gtccttcaga attgacagaa cgtgaaaatt
     4081 acaagttgct gattggttca gtcatcccta gaccagtagc agtagtaacg actaaatcag
     4141 caaaagatat agtgaatatc gcacccttca gttacttcaa tatcgtcagt tcgaatcgac
     4201 ccatcttatc cttggcgatc cagagaaaac aagatgcagt aaaagacaca gcaaagaata
     4261 ttcttgagac aagagaagct gttatccata tccttgatga ggacaacgta gaagaagtaa
     4321 ataaaacagc agccaatctg cctaatgagg aaagcgaact gtacctgact gacttgactt
     4381 taactgattc agtaatcatt tcagtaccag cattgacaga agcaaaagtt cgttttgaaa
     4441 catccttata tgaacatgtc gagatacgga ataaaaataa agtaacagct gatttatttt
     4501 tgctagaagt acagaaatat catttaaatg aaacagtcta tgatgataag acaggaagga
     4561 tcgatccaag aaaattgaat gctgtaagcc gtttggcagg aaatgattat gcagcaatag
     4621 gagaaatttt cacgattgca cgtcccgaat aaaaaggagc actagttatg ttaaaaataa
     4681 gctataaacc atcgacagat tcaaaagaaa tgaaaaaaga atatgaaaca gtgaatgatt
     4741 ttctgcaagg gcagtactta gaagttccgc cattgcaaga ccattttgtc gttactactg
     4801 ttactttaga tggtaaggaa atagaaatgc cagatcaaac gattagcgga ttgtttaatt
     4861 actttaacaa ataaatattt attccgaaaa gtgaaaaaac atataaaaaa acacataaaa
     4921 ctaaaaaatt atcaaagaat cctggtgcaa ctgaaagaat ttgcaacggg attctttcaa
     4981 cttatttgtt atttttttct aaaaaatatt aaagattgtt aaatttcact atttcatttc
     5041 aaattccatt gcctaatcat taggaaaagt ctatcatgaa ctcgtaaata gaatatagta
     5101 ataaccttgt taggtgaggc tcctatacaa acataggctg ttgcccagaa acgtcgaaag
     5161 tcgccaatgg gtaaaacaga aactgttgga ttaaggcttt ttccaatagc taagaatgtt
     5221 ttctttacgt tgtatagtgc taaaactcgg acgatgagat gatgctaggt cagaattctt
     5281 gttcgaaaag gtttctgacc ttttctttat atttttgtga ctgacttatt tgatgagaca
     5341 aactcgctcc tcacctgaca agtggattgc tgtgtgagga ggagatgcgg tgaaaaaaga
     5401 tcgattggtg gaggtcgctc ggattcactt ctggttgcac aatacaacca gaaaacacaa
     5461 caagcaaaac tgatctctat catgagagat tcatatgtcg atattccagg ttacggaatg
     5521 aataagataa atgcagctta ctcttatggg ggagttgatt tattaaatca aacattaaag
     5581 gaaaatttca aatttgaagc tccctattat gcaagtatca catttcaaga ttttatcgat
     5641 tgcgttaatg aactgtttcc tggtggagtc aagatcgatg cagaaaaatc tctagattta
     5701 gatggcgtat atataaacaa aggagagcaa gtgatggatg gtaatacttt actccagtat
     5761 gctcgatttc gggaagacaa agaaggagac ttcgggagga tcagaaggca gcagcaagtg
     5821 atcaaagcta tctctcagca gctgaaagac gtaacttcaa tattcaagct acccaaagcg
     5881 gttgggaaat tacttggtag tatccaaacg aaccttccag aaagtgtgct tctggattgt
     5941 ggtatggatt tcctcaaaga catatgttag aataaacagg tataaatagt gaaataaagg
     6001 aatgacaagc aagagaagga ggaaaaaatg aaaagaagtg acaagcacgg caaaaatcga
     6061 acaggcgctt atattgccgg cgcagtgatc ttaatagcag ctgcgggtgg cggttatttt
     6121 tactaccagc actatcaaga aacccaagca gtagaagctg gagaaaagac agttgagcaa
     6181 tttgtccaag ctttgaacaa gggagattat aacaaagctg cagaaatgac atcaaaaaag
     6241 gcggcaaata aaagtgcatt atctgaaaaa gagatcttag ataaatacca gaatatatac
     6301 ggtgctgctg atgtcaaagg acttcagata tcgaatctaa aagtagataa aaaagacgat
     6361 tctacttaca gtttttcata taaagcaaag atgaatacct cattaggtga attgaaagat
     6421 ctttcttata aaggaacatt agacagaaat gatggtcaaa ccacgatcaa ctggcaaccc
     6481 aacttggttt ttccagaaat ggaaggaaat gacaaagtaa gcctgaccac acaagaagca
     6541 gcaagaggga atattataga tcgaaatggt gaaccattag caacaacagg caaactaaaa
     6601 caattaggag tcgttccaag taaacttgga gatggaggcg aaaaaacagc caatatcaaa
     6661 gcgattgctt cctccttcga cttaacagaa gatgctatca atcaggcgat ttcacaaagc
     6721 tgggtacaac ccgattactt tgtcccattg aaaatcattg atggagcaac gccagaactt
     6781 ccagctggag ctaccattca agaagtagac ggcagatatt atcctttggg tgaagcagct
     6841 gctcagctga ttggttacgt gggagatatc acagcagaag atattgataa gaatccagaa
     6901 ttaagcagta atggaaaaat cggtcgctca ggtttggaga tggcttttga taaggatctt
     6961 cgtgggacaa caggtgggaa attaagcatt acagatgcag acggtgtaga gaaaaaagtt
     7021 ctgatcgaac atgaagttca aaatggcaaa gatatcaaat tgacaatcga tgcgaaggca
     7081 caaaaaatag cttttgacag tctaggagga aaagctgcat caactgttgc gacaacgcca
     7141 aaaaccggtg atcttcttgc gcttgctagc tctccaagct atgatccaaa caaaatgaca
     7201 aacgggatct cacaagaaga ttacaaagct tatgaagaaa atcctgaaca tccattcatc
     7261 agccgatttg cgacaggtta tgctcctgga tctacgttta aaatgattac agcagcaatc
     7321 ggtctcgaca acggcactat cgatccaaat gaagtgttga cgatcaacgg gcttaaatgg
     7381 caaaaagaca gttcttgggg atcttttaaa acaacgcgtg tcagtagtga tgtatcacaa
     7441 gtagacttaa aaactgcttt gatctattcc gataatatat atgcggcaca agaaacgttg
     7501 aaaatgggtg agaaaaaatt tcgtacaggc ttagataaat tcatttttgg tgaagacctt
     7561 gatttgccaa ttagtatgaa tccagcacaa atttctaatg aagatagctt taactcagat
     7621 atcttgctag ctgatactgg atatggacag ggcgaacttc taattactcc tatccagcaa
     7681 gcagcaatgt attctgtttt tatcaacaat ggcacacttg tctatcctaa attgattgca
     7741 gataaagaga caaaagataa gaagaatgtc atcagcgaaa cagcagtaca aacgatcgtg
     7801 ccagatctga gagaagttgt gcaagatgta aatggtacag cacattctct ttctgcttta
     7861 gggattccgt tggcagcgaa aactggtaca gcggaaatca aagaaaaaca ggatgtaaag
     7921 gggcaagaga acagtttctt gtttgctttc aatcttgata accaaggtta tatgatggtc
     7981 agcatgttgg aaaataaaga agatgatgat tcagcaacca aacgagcatc ggaactattg
     8041 caatacctca accaaaatta tcaataaaaa attgcttttt aagtacagta aaaggactgt
     8101 ggcgttatcg tcacagtcct tttttcaaat aaacggtttt cacgatgtct ctttcacaac
     8161 ttctttttga tttactcaca cttcataaac tttttttgta aaatatttga gaacaagtgg
     8221 agaaataagt gtacttaata aaatcacgat aactaaaggt gaatagtact gtggttcgat
     8281 caattgactt tgctgtccaa tttgtaaaat gatcaaagcc atttctccac gcgaaatcat
     8341 accagcaccg accatcaatg aactatgttg agaaaaaccg gcaatctgag caccaaaata
     8401 acctccaagc aatttggtca aaatcgctac aagcgtcaat atagaaataa agagtagttg
     8461 ttcactaaag tcagaaaaat caacttctaa tcctacactg acaaaaaata ctggtataaa
     8521 tactgcatat cctaaagcct ctacattgtg gtatacttct tctttaacct ttgtctgact
     8581 gacagctatc ccagcaaaaa aagcaccaat gacagagcta agcccaacaa gatccgctac
     8641 gtaagacatt cctaaacaaa taactagcga tacgatgata atagaagaat ttgcgtacac
     8701 tttttctgca aatgaaagta ggaaaggcgc aatccatttg actaataaga aaataaaaac
     8761 aaaataaatt agctgttcaa tcaaaacaag cggtaaagaa gcattgctag aagcttcccc
     8821 cgttagaaaa gataggctga aacttagaac taaaacgact aaaatgtcat ctaccacaga
     8881 agcacccaaa attgttgatc cttcttttgt attcactacg tttagttctt ttaatacttc
     8941 tactgaaata ctgacagaag ttgccgcaag aataatccca aagaaaatcg cttcatttcc
     9001 cgaaacttgg aatgctttgc ctgtcaacca gccaaaaaca accgggaaga tgatcccaag
     9061 caaagcaacg aacataccag gtcggaaata ttttttcaaa agagataaat cactttccag
     9121 accagctaaa aacattaata agatcacacc aatctccgaa aagtcatgga ctagaatatc
     9181 aggtttgacc caattcaatc cagcttggcc tagcaaaaca ccaacaagta attgtccaat
     9241 cactgctggg atacctaatc tccgcgagat atgtgagcca atcgttgttg aaatcaatat
     9301 caggcataaa ataccaataa attccattct catcattcct ttgtataaaa tatagcccga
     9361 acttagcata acatacatta ttgaaaaaat aggaaaatat actcacaaaa aaaccaacaa
     9421 tccaaaagat ttttttggat tgttggtttt tatacggtct attttaataa ctaaaaatga
     9481 ttaacgtata gtcatttttc ttattctgat gaaattgata atctcctgga tgcccatgaa
     9541 aatcaaaata aagccgaata tttggaatag aagcatcaaa cttttgaatg gattgaacaa
     9601 taagacgaat ccgccaatca acaacagaat actactataa acactccaac ttttagcttt
     9661 tgtattcatg ctgaagaaca actggaacaa gctgttgatg ataacagcta atccaagaag
     9721 aatcggcagg atagaaacga ttgcaggtgc aaaagcatag acgatcagag ctaagatcag
     9781 gaaaaaaaga ccactgaaca gaccgatact ccaagaacct gttttccttt taaaacggta
     9841 agcctcaaaa agattcaaca acccaagcaa aacaagatag gcggtgatca gataaccgat
     9901 aaaatgaaaa acagcagaag ggtttagcac aatcgcaatc ccagaaataa tataaacagc
     9961 agctcttaat aaggcgtatt tttgaatatt ttgtttaatc gtctcaaaca tataagaaaa
    10021 cctcctttga cttattttaa cgtgaactag tcattttacc aaattaaatg ttacaaaatg
    10081 agcgaaggag aagaatatct ctggaaaaat caacttctga ggatcttttc catttttttg
    10141 ccttttgcta gctcatcgat cattttatct aaataacgaa tttctttcat caagttatcc
    10201 tcgatgtctt ctactcgtac accacaaaca acacctgtaa tcaaggaacg tgaaggattg
    10261 gggacagggg cttccgcaaa aaattgttcg aaagtcactt gtttttgtag ttgatattct
    10321 agttctgttt gggaataacc cgtcagccaa caaatgattt catctacttc ctcttttata
    10381 cgatcttttc tctccgcttt tgctacatac ataggataaa cgcttgcaaa acttgtcgta
    10441 aaaatacgat tttgcgccat aatcagtcac ctttcttttt ttcaaattat ttactactta
    10501 tagtatataa gaaaaagaga agaaaaagcg attattcaaa aaaacaaaaa ggattgtgac
    10561 aaaattcttg tcaccatcct tttttccgct ctctgacttt ttacaatctt catagctcaa
    10621 gtgcgcatca gataatcgaa tgctcctaaa gctgcagtag ctcctgaacc cattgaaaca
    10681 atgatttgtt tgtatggact atctgtacaa tcaccagctg cgaaaacgcc ggggatattc
    10741 gttgcgccat ttttctcggt cactatttca tttcttggat tcatttcgat cgttctatct
    10801 agccaatccg tattagggag taagccgact agaatgaata ctcctgaaac agctagtgta
    10861 tgcatctcca tcgtacggcg atcgatatag gagagagatt ctacctgatt cgtaccgctg
    10921 atttctttcg tcgctgcatg tttgataaca gtgacattcg caagagagac tagtttatcc
    10981 tgtaagattt gatctgcttt taattctggt aagaattcta gaacatatac atgttttgct
    11041 aacccagcca aatcgattgc tgcttcaaca ccagaattac caccaccgat aacagcaatc
    11101 tcttttcctt taaataaagg gccgtcacag tgtgggcaat aagcaattcc tttattttta
    11161 aactcttttt cgcctggtac attgatagaa cgccagtgcg cacctgtcgc gatgatggcg
    11221 gtttttgctt taagtgatat accgttagct aagccaatat taataaaatg ttgctcttta
    11281 tttaaggaaa cggcctgttg attcatcata atgtcgatag ggtaactacg cacatgactt
    11341 tctacttgct gcatcaattt tggaccttct gtgtaagagg taccaatcat attttcaatc
    11401 cctagtgttt caacgacttg tccgccgaaa gaatcagcga caagtcctgt acggattcct
    11461 ttacgtgctg catagatagc tgcactacta gctgctggtc caccgccaat cactaataca
    11521 tcataaggtt ctttttcaaa caactcttct tcaatcaaag ggccagtgat tttttcaaca
    11581 atttgttcga tcgtcatgcg tccgctacta aattcttctc catttaaaaa cacagttggc
    11641 actgccatga tttttttatc atcgatttct ttttggaaca tcccaccttc aatcatcgta
    11701 tgagtaatat ttggatttaa tacagctaat atattcaatg cctgtacaac gtcggggcaa
    11761 ttatgacaag tcaagctaac ataactgtca aaatgcaatg tttgtgttat ttttttgatt
    11821 ttaagactca aagattcact gattttcggt gcccgtccac taatttgtaa catagccagt
    11881 aaaaaagagg aaaattcatg accgaggggg ataccagcaa aaacgattcc actttctttg
    11941 ccaactggat tgatagaaaa actaggtgtg cgcatcgaat ctcttttttc ccaagagatt
    12001 ttaggagaca tttctgctat ttccttcgta aattcagcta gtttttgact attttcacta
    12061 ttatccaaac taacagaaaa aacaatagga gattcaatca gtgctaaata ttgttcgaga
    12121 ttttgtttag tttctttgtc taacatatcc accacctaaa tctttccaac aagatcaaaa
    12181 cttggtttca atgtttcgcc actttctttc cattttgccg gacaaacttc acctgggtgg
    12241 gtacgtacat attgagcagc gcgaatctta tcaatcagtg cactagcgtc acgaccgatt
    12301 ccatctgcat tgatttccat agcttgaacg attccgtctg gatcaataat aaatgttcct
    12361 cgctgagcta atccttgctc ttcatccaaa acatcaaaaa tacgagaaat ctgatgagac
    12421 ggatcaccga tcatcacgta ttcgatttta ccgatagcat ctgatgtatc atgccatgct
    12481 ttgtgagtaa agtgggtatc ggtagagcaa gaaaagactt caacacctaa agatttcaat
    12541 gtactgtatt gttcttgtaa gtcttctaat tcagtaggac aaacaaaagt aaaatcagct
    12601 ggatagaagc aaagaatact ccagttcccc ataagatctt tttcactgac ttctaaaaat
    12661 tctccttgat gataagcatg tgcattaaat tcttcgattt ttttcccaat caatgacata
    12721 gtaaaacctc caataataat tatttattta taattattgt aatttagttg gagttgcaaa
    12781 gtcaatggat attttgttat ttaataaaga ttactcaaaa acgaaggtta attataaaaa
    12841 tagaagaggt cgcaagaaaa tgctactgct ggaaatactc gggataacgt tgagtaacag
    12901 tttcctgttc tttcagcatc atgtgtaagt gcaatcccgt ttgaaatcga gcttcttctg
    12961 gttttttatc aactaaagcc ttgagtaaat cataatgttg ttccatgatc gtttcccatg
    13021 gaagcccctg aatggtcact cgtaaccagc ggaaacgttc taaatgggta ttatggtcat
    13081 ctaaccagtt ccaaacttct tttcttcctg caatttcgaa acaagcttca tgaaataaat
    13141 tatctgcacg gaaaaaagcg cgttcgtcat ttattttgac tgctttttct tgttcttcta
    13201 aaatcgtttc tagcactatt cgtgtttgtg tgtccaattt ggaacaacat tcaatcatga
    13261 tttgctcttc caactgttct cggacaaagc gagcattttc tgcagaaaca agattaattt
    13321 tggaaacata cgtaccactt tgaggtatcg tatacacgag ttcttgctga cgtagttgaa
    13381 tcaatgcttc gcgaatggga gtccggccga tagcaagatg ttcctccagt gccttttcag
    13441 atattttcct tccaggttct aagtcagcat agataatttg tttacgaatc gcttgataag
    13501 cttgtgattg caagctgctt ttcatcttta ttcctccaaa atcatttcta tgaacgtagt
    13561 ataacagaag aggtctgaaa aacaatctgg tatgtcacat taactagtaa atttgtataa
    13621 atagtaaaat tttggttgac atagcgattt ttattgcata aaattcactt gaatacaaaa
    13681 actaatatgt tagtttagga ggggaaaaat gattgattta aacaactgga ggaactttat
    13741 ccctgaatta tctcaaaaag aagtagaaat acctcatttt gaccgtgcat cattaagaga
    13801 aaatggacaa aaaaatcctg tctggatcca tttcggtggc ggaaatcttt atcgaggatt
    13861 tcatgcagaa atcgctcaac gtttagcgga tctaggcgaa ttgtccactg gtgtcattgt
    13921 ttgtgaaaca ttcgatgaag aaataattga aagggcttac caagattttg atgatttgat
    13981 tcttgaagtg gtcatgccaa gcagtggaga gttcgtcaaa cgtatattag ctgcgacagc
    14041 tgacagtctg tattgtcatc cagattgttc tgaacacttt gataagatga ttcgacactt
    14101 tgaaaatcct agtttacaat tagttacttt tgctattact gaaaaaggtt atcgattgaa
    14161 agatacaaat aataaatata taggaccgat tgcagtcgat ataaaaaatg gtccaaagaa
    14221 gccatcacat acaatgagta ttcttgctgt gctactttat aaacgttttt tatctggagc
    14281 ttggccgatt gcacttgtct ctacagataa tttttcacaa aacggtagtc aattacgtac
    14341 ttctttgcta acgatcgcaa aagaatggca aaaggaaggt tatgtacaaa atacatttat
    14401 ccaatactta tcgaatgaag aaattgttgc gtttccatgg acgatgattg atcgtatcac
    14461 cccgaatcct tccttgtcag ttagcaaaat gttggcaaaa gagggctttt caaatatgtc
    14521 gattttccaa accgcaaaag gaaataatat tgctccattt gtcaatacag aggacatcca
    14581 ttatttaatc atggaagatc attttcccaa tggacgtccg aaattcgaaa aagctggggt
    14641 attcttgact gatcgtgcaa cggtagataa agcagatacg atgaaggtga cgacttgcct
    14701 taatcctttg catacgtctt tagctattat gggttgttta ctggggtata ggagcatagc
    14761 tgaggagatg aaagatccag atttatcgct gctagtttct gaaatcgggt acaatgaagg
    14821 cctcccagtt gtggagtctc caggtatcat tgatccaaag atctttctgg aagaagtaat
    14881 tactgtgcgc ttttctaatc caaatattcc taatatgcct cagcgaatcg ccacggatac
    14941 ctctcaaaag gtggcgattc gttatggtga gacgattaaa aaatatatgg aaatagaagt
    15001 taaagacccg cagacacttg tattcatacc attgactctc gctgcttggc ttcgatacct
    15061 tattggcatt gatgatcaag gaaaaccatt catcccgagt ccagacccac tattgacaga
    15121 ccttcagcat aagctttccg atattcaact gggtacgcaa gatacatcac atattcatga
    15181 gaaaatggct cctattttgt caaataaaga aatttttggt gtagatcttt accaagcaga
    15241 gcttggcaga aaaatagaag aaatgttcat caagatggta gcaggaccaa atgccgtacg
    15301 aaaaacatta caggattact tacaagaaca tggaggaaat ttatcatgga aatgactttt
    15361 agatggtacg gatcacagga agaaaagatt accttagatg aaatcagaca gattcctgcg
    15421 gtcaaaggga ttgtaggcac attgatggat ataccagtag gagaggtatg gcctagggag
    15481 aggatcaaag aactaaaaga agaaattgag tctcgtgggt taacactaaa agtaattgaa
    15541 agcgtcaatg tgcatgatgc cattaaaatt ggattacctt cccgtgagca gtatatcgaa
    15601 aactataagc agacaatccg aaacttggca gaatatggaa tagaagtcat ctgctataat
    15661 tttatgcctg tatttgactg ggtgaaatct gaccttgact accgcttaga agacggctca
    15721 tccacgttag cttttatatc tgatgatatt ccagatgatc caagagaaat cgtcgcgcgc
    15781 atcgaacatt ccagcaatga atttggattg ccgggatggg aacctgagcg cttagctcct
    15841 atcaaatcct tgcttgaagc ctatgcatca gtagacgaag aaaaacttcg agaaaatttt
    15901 gcctattttc tccaatcaat catcccaaca tgtgaagagg taggggtcaa aatggctgta
    15961 catccagatg atccgccata ctcgattttt ggattagctc gaatcgtaaa gaatcgagaa
    16021 gatttagatt ggttgtgtcg catagtagac agcccttata acggaatcac tctttgtaca
    16081 gggagtattg cagaagatcc agaaaatgat gtatatggga ttttagcaga attttgccaa
    16141 agagatcgaa tcccatttgc acatgttcga aatattaaat ttttagctaa tcgagatttc
    16201 tatgaggcac cacataaatc cgaatacggt tcattagaca tgtaccgcat actaaaaaca
    16261 atgtatgaca acggatttaa cggatacatc cgtcctgatc atggaagaat gatctggaat
    16321 gagacaggaa gaccaggata cggcttatat gatcgagcat taggtgctgt ttatctaaat
    16381 ggattatggg aagcaatcga aaaaggaaac aaaagtaaag ataattagtg aaaaaaactg
    16441 taattttatt atgtaaataa gaaggatgtt caaattcttg atacataaat ccggaggttg
    16501 ttaataagca ttcggattta tgtatcttat ttggtctagg aagtaacttg attttctttt
    16561 ttcgattgat ccatgagtgc ttcttctttt aattcaaaga tatattctga gatcctcata
    16621 atcacttttt tccagtcttc tggtgtgatg attcctttta aaatatagat ttttttgata
    16681 tgagaaggca attgtttcaa agggcagtcg ctgataacga tgttgcagtt ctccataaaa
    16741 tcattttgta ttttgatcga ttcatttgaa aaaatttgtt ctatcttaac gatcagatct
    16801 ttactgatat aaaaatcacg cgtatagttc acaccaatca caattcgcgg ctgttttttg
    16861 tagcgatcat acaaatgtac taggtcttca accatccatt gcacattttc cttttctaaa
    16921 ataactggta acaagtgttg attttgttct ctgaaatcca tataaaattg ttcaatggcg
    16981 gtttggactt ctttcaatac gctatgttct tgataaagca tgaaagtagg aaggggcgta
    17041 tttggttgat tgaagttaag aaatccatta taaagtttat ttcgtgcgaa tgccaatgag
    17101 taaagaatct tttctttttc aggtataaac aaatcaaata cagtacaaag ggactccacc
    17161 atttctcttg aataaagaac atgaggaacg tttgcttttt ttaaaagttt gtattgctcc
    17221 aagcttgttt cttccgattc gattttcgtg atagaaagtc gagctaaaat attcactaag
    17281 atgcgttgtt cgcgacaaat tggcagatta ggtcgcaaaa tatctacaga gagatcaata
    17341 aaaaagtcaa tatattcata ctctgtgaat tctttttgta cgtctttcac agaagttgca
    17401 ggaaaattct ctttacatat ttttaataga aaatataatt tatctatcat accgctattt
    17461 agtcggtcaa gtacttcttt tttaaaaaaa gtattcatca taaaagccac tacttgcgga
    17521 tcttcatcat aaaattctgt agcagtactt gaaaagatgt tccaataaat atctaatgct
    17581 gcatattgaa tttgtacctc ttttccagaa aaagactttc tgccattatt agaaaaggag
    17641 atagacaaac cgtactatgc taaaaatgca ttaatctttt tcattttcgt atacaaataa
    17701 gaggcactat agtttgtttg ctgactgaaa ctgataatcg aatttgtctg acagctgaac
    17761 aaagaagtca agatctgata actgactgat tcgttgcagt atcttccaaa tagacgataa
    17821 tagcagtaag ccggatcaat tccttcaaaa ttcaacttta aaaaaggttt ttgcttatca
    17881 atatgcagtt ctgttagatt gagacgctca aagtcttgtt ctaattcttt gatgtatagt
    17941 aaaaaatttg attcagacat atggaaatga tctgctaaat attgtgtagt aataaagaaa
    18001 cgatgttcag ataggaaaag aaaaatatct aattttgtat tgcttttttt cttcaagata
    18061 aacgttttaa tcgcttcttg agtttgcatg aaagaggctc ctttttactt aaattgttaa
    18121 aacttgaaaa tattactgtt tttttcataa atttagacaa aaaaacagta aacatatagg
    18181 tagaatctct actatcttat ttcttgcata caaaaaaatc aaggagtgag agagttatga
    18241 gatattcaac catcttaata tcaacatttg cagccttaag cttatcgctt actataaatc
    18301 agacagtcca cacagaggag acagaaacag ccaaatggac agaaaccaag tgggccaacg
    18361 tcaatcgaat tacctttcag gatgaatttt catccttcaa ttcaggagtc gcaaaattaa
    18421 gaaaaggaca aacagcgacc atcaaagcaa aaattgacta ttcgggagac ttagcaccta
    18481 tactacaatc agctgttaca tttgagaatg ttgatcccac tttgtcgatt ggctatgacg
    18541 agaacacttt gactatccaa cacaagcaag cgatatttac cttcaccgtt acattaaatc
    18601 aggacttgtt aaaaccagcg ctttttactg tcaaggtatc agatggacta ccgaacgatc
    18661 atcatttaac gccgtatagt cagcggcaga caattgagca agattcagcc atcgactcag
    18721 gaggagatct tgttgaagaa ccaacagata aaccagaaaa tgaaaataag ccagaagtac
    18781 cgcctacaga aaatccagac ggagaacaga aaccggaaat agaacctgga gaagaacccg
    18841 atacagaaac tcaaccagag ccagacaata aatcaaaacc tgaaataacc cctggagaaa
    18901 aaccagatgt aactccagaa ccagatacgg attctggaaa ccaaacagta ccggaaacaa
    18961 atccagacac agataatgaa actgaaaatc cagaaaaacc agaggtagat ccagaagaaa
    19021 aaccagatgt gactccagaa ccagatacgg acgcaagaga ccaaggaata ccagaaaaaa
    19081 taaacaaaaa aacaattcaa gaggatggaa aaaaagagag taaaaaatca aatctagcaa
    19141 ttctaaaaat aaatgaagag cagctgaata aaaaatcacg aatatttgat agcgcccaat
    19201 cagctgaaac cttaaaaagt agcaaggata caacctttgc tgtcctgaaa cgaaaaataa
    19261 acagctacca aaatccggag agtcacaaaa caaagttata ctgtggagcg gaatcattct
    19321 attaagtata gcaacaatgc tttctgcaaa aagatttaaa caaaacagat ctctctaaca
    19381 tttgaataat gtctgtgaac gcatttttca aataaaaaga aatatccaga aaatgacccc
    19441 aaaataccag attgaaatct gatatttggg gtcgttcata ctttatcttt cttcatattt
    19501 attttaaggg atatctgttt cttttggaag atggttcggg atctttttca ctttcaatac
    19561 atctaaaaag aaggtaaaga tcggaatgcc gacaatcaag ccccaaacgc caaagaaccg
    19621 ttcgctaaca agtaagacca caaatgtata aaaaatcggc agttctgttt tgctggacat
    19681 caacttcgga ttcagcacat aagactcaat tagatggaca atcaaaatcg taatcaggat
    19741 ataaacaaca tctcggatgc ctccttggga ataagctatg aaagatagag gaatacaaga
    19801 aatgataaca cctgctactg ggatcagact taaaatgaaa atcatgatcg ctaaactcag
    19861 cagctgatga aagccaaata cagccaaggc gattgtagtg agcaacgtat ttaaaagagc
    19921 gacaacaaat tgagcttcta ataccaaacc aaatgtattg acaaacttat cggcaaaata
    19981 gtaaatatct tgaaagaacc aagaaaattc actttttaaa aacaatcttg agaatacaat
    20041 tgtttttttc ttttcaatca taaaaaagaa acttaagatg aatgacatag caaacgccac
    20101 tgccattttt cctatatcct gtaaatagcc aagcgcaatc gaagcgccat tttgaagctg
    20161 ttcaaaaaaa tcgtttcgct caatataagt atggatatat tgtaaaacag gatctgcatc
    20221 ttttggctga tgctcgtaaa aatcaataac ggactggatc atatcaaatg tttgatgaat
    20281 aagcatcggg atatactttg tgaatgccag atagataagg taaacgatca gtgtataaat
    20341 catgatagct aaaacacctg tagggattcg gacaaatcgc tgaatgattt gaacaagatg
    20401 aatcatcaaa taagtaaaga taaatgtgag caaaatggtt gtaatcatac ttctaactaa
    20461 gaaaagaaca aaaacgacaa ataataaaac agtgagacgg cgtatttttt cattcgccaa
    20521 aaaacgctga taaacggtca aatcgacaac ctccaaataa caaaaaataa acacgttatt
    20581 cattatatga tggaatatga aaataagaaa gagaaagagc aaaaagaaaa accgctaaat
    20641 gacgttatct tatgagttgg ttttcctcat aaaatcgttc atctagcagt ttcagccctt
    20701 tttctggtct tgatgaaaat tatctagcat ttttcgggtc agatgttgca gtgtatccaa
    20761 ttcttcctgt tcaagtggaa gataagactt gatcttttgt ggaatacctt ctgcttgttt
    20821 ttgcaacgca gcaccttgag gagtcagcgt aacatttacg attctttcat cacccgtttc
    20881 acgctgacga ttaatataat ttttttctgc taactttttt agtaagggag tcagcgtacc
    20941 agaatccaga cacaaatcat ttcctagctc tttcactgaa gtctttttct tttcccataa
    21001 aactaacatc acaagatact gggtataggt aagattcagc ggcttgagga gggaagtgta
    21061 gtgtctaatg atttccttag aggcggcata taaaggaaaa catacttgat taactaaata
    21121 tagatcttcc atttttccac ctccgctgtt ttactatagt gtatcatagc ggatttacac
    21181 aaaaaagtct attcactaac tgctttcaga gtaacttcta tatttccagc tgtagctttt
    21241 gaatacggac acactttatg cgctgcctct aataattctt gcgtttcttc cagagaaaga
    21301 ccttcgatag atccttcaat ctctacacct aagacaaagc tcgtttcact ttctgaataa
    21361 agggaaactt gtgcactgac agtagaagcc ccagagatat ttttttgctg tttgatcaat
    21421 tctaatgcac tgttaaaaca tgcactgaaa ccagctgcaa acaattgttc agggttggtt
    21481 gcattttcga cgcgtttacc aggagctgca atattcaatt cgaatgtacg atcgggatta
    21541 tgaacttctc cagagcgtcc gcctgtgttg atcattttcg tagaatacat ttttttcata
    21601 aaattaccac ctttaattat attttataca attgaatttt acacaatata attgtggaaa
    21661 gcaaagaaat ggattggcat aagataaata agagaaagca catgaaacag acgcgctttc
    21721 tcgaatagca aacatataca aaaaaatatc agagacaaaa actaatctca tcataaacat
    21781 tacatatatt tctcaaaaag ttgttttctt tcttcaaaac ttacttcacg atggacctga
    21841 tgaagcatcc ataaataacc aaaaggatct ctgaacattg agttagtcac accaaagtcc
    21901 atcatttctg tcatttcttg aatctctaca cagccatttc gtaatgcttt attatgtgtg
    21961 tcctcgatat cagagacgat gatattgaac cagatcgtat ttggatgttc agcagtagga
    22021 gcagtcaaac caagagacgt gttttcatcc agcatatgga atctcgtgcc atacaaggta
    22081 aaaatgactt cattattgcc tctagggtaa tctgttgcct caatcagttg tatttcatca
    22141 aagattgttt gatacagttc tagtgctttc aaactatcat ttaatacaaa atctatttcc
    22201 gttcctttat gcataaagat ctcctctcct tttcagtcga acagttacta gattctttta
    22261 ttataccagt taaagaaaac gcattcaaaa aaatagcgga tttacttacc aactcattcg
    22321 attggatgat aagtaaatcc gcgtcccatt acttctgcta cgctgctgac aatgacaaag
    22381 gcacttggat cgatttcttc tatcaatggt ttcattcggg aaaattcatg atcagtcaca
    22441 acgatcaata aaacctcttt tgactttcga ttatacccgc cttttgcctc tagcagggta
    22501 aggccacgtc caatctcagc acttaagcga aggcggatgt cttccaaata atgttcactc
    22561 atgaccataa cagatttctt tcgattgata cctgtttcga tataagtcat gacaattgaa
    22621 gtgattgcaa tagataaaat agcataaaga aactcttcta ttccaaaaac aaacagatta
    22681 agagaaacaa cgaatgcgtc tgtaaaaaat aagccaatcg aagtattcaa gtggaaatat
    22741 tttttaaaaa tgaggggagg gatcgtcgta ccgccgctag aagagttgtt tttatataaa
    22801 atcgcaactc ctaaagcaaa aatcgcactt ccaaaaatga cagacaacaa ccgatctgaa
    22861 gtaatcattg tttctggaac tattgcaatg attaaaggaa aaaacaagct tccgaaaagt
    22921 actttaaaaa agggtttttt acctaaaaat agaagagcta gtaccaacat aacgatattc
    22981 aacactaaaa taactatagc tcggtcaaat cctaaaacag cttccagtaa tattcctaga
    23041 ccgctgacac ctccagcagc aatatgatga ggccctaaaa acatattgat agcgactcct
    23101 aatatgaaga gggcaaaaat aatcttaatg tatgtccata taaattgtct cgtttctttc
    23161 atttatcca
//
LOCUS       DAZKCH010000043        22719 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000043 DAZKCH010000000
VERSION     DAZKCH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.043"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(11..1942)
                     /locus_tag="ACG84X_001660"
     CDS             complement(11..1942)
                     /locus_tag="ACG84X_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFP9127527.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1960..2874)
                     /gene="pfkB"
                     /locus_tag="ACG84X_001661"
     CDS             complement(1960..2874)
                     /gene="pfkB"
                     /locus_tag="ACG84X_001661"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFP9127528.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2871..3623)
                     /locus_tag="ACG84X_001662"
     CDS             complement(2871..3623)
                     /locus_tag="ACG84X_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9127529.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3782..3991)
                     /locus_tag="ACG84X_001663"
     CDS             complement(3782..3991)
                     /locus_tag="ACG84X_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127530.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4002..5330)
                     /locus_tag="ACG84X_001664"
     CDS             complement(4002..5330)
                     /locus_tag="ACG84X_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127531.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            5466..5621
                     /locus_tag="ACG84X_001665"
     CDS             5466..5621
                     /locus_tag="ACG84X_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFP9127532.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5695..6282)
                     /gene="yihA"
                     /locus_tag="ACG84X_001666"
     CDS             complement(5695..6282)
                     /gene="yihA"
                     /locus_tag="ACG84X_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFP9127533.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6365..7615)
                     /gene="clpX"
                     /locus_tag="ACG84X_001667"
     CDS             complement(6365..7615)
                     /gene="clpX"
                     /locus_tag="ACG84X_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFP9127534.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7862..9151)
                     /gene="tig"
                     /locus_tag="ACG84X_001668"
     CDS             complement(7862..9151)
                     /gene="tig"
                     /locus_tag="ACG84X_001668"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFP9127535.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9305..10237)
                     /locus_tag="ACG84X_001669"
     CDS             complement(9305..10237)
                     /locus_tag="ACG84X_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127536.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHQVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10394..11053)
                     /locus_tag="ACG84X_001670"
     CDS             complement(10394..11053)
                     /locus_tag="ACG84X_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFP9127537.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11056..12081)
                     /gene="sppA"
                     /locus_tag="ACG84X_001671"
     CDS             complement(11056..12081)
                     /gene="sppA"
                     /locus_tag="ACG84X_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFP9127538.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12094..12384)
                     /locus_tag="ACG84X_001672"
     CDS             complement(12094..12384)
                     /locus_tag="ACG84X_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127539.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12793..14598
                     /gene="glmS"
                     /locus_tag="ACG84X_001673"
     CDS             12793..14598
                     /gene="glmS"
                     /locus_tag="ACG84X_001673"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFP9127540.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14670..16025)
                     /gene="glmM"
                     /locus_tag="ACG84X_001674"
     CDS             complement(14670..16025)
                     /gene="glmM"
                     /locus_tag="ACG84X_001674"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFP9127541.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16049..17218)
                     /locus_tag="ACG84X_001675"
     CDS             complement(16049..17218)
                     /locus_tag="ACG84X_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFP9127542.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17215..18102)
                     /gene="cdaA"
                     /locus_tag="ACG84X_001676"
     CDS             complement(17215..18102)
                     /gene="cdaA"
                     /locus_tag="ACG84X_001676"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFP9127543.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18291..21983)
                     /gene="nifJ"
                     /locus_tag="ACG84X_001677"
     CDS             complement(18291..21983)
                     /gene="nifJ"
                     /locus_tag="ACG84X_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFP9127544.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22182..22703
                     /locus_tag="ACG84X_001678"
     CDS             22182..22703
                     /locus_tag="ACG84X_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFP9127545.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         6326 a         4932 c         4041 g         7420 t
ORIGIN      
        1 ttttttattt ctatgcttct gctactgcag gagcttttct caataaacca taaatcacac
       61 cagatacgac tgctccgata gcaataaaca ccaaatacat gaccgggtga ctcagtaaga
      121 atacaacgaa aatcccgccg tgaggagcca gtaatttgat tccgaaagct ccgactaatc
      181 cgccagttaa agcagaacca ataataaaac ttggaatggc acgaatcggg tcagctgctg
      241 caaatggaat cgatccttcc gtgacaaacg atagtcccat cacgatgttc gtcaaaccag
      301 catcttgatc tgttttgctg aatttattct taaacaaacg tgtagcaacg aaaattgcca
      361 atggaggtac cattcctcca gccataacag aagccatcac gacacttccg ccagttgcaa
      421 cagtcgtagc taaagttgct gtaccaaaca cataagcggc tttgttgatt ggaccgccta
      481 aatctgccgc catcattcca gctaataatg caccaagtaa agcagcattc gaaccactca
      541 tacttgtcaa gaaaccgttc aatgcatcat tgattgcttt catagggaca ttgaccagca
      601 acatcaagaa accagtaatc agtaagccaa acactggata aaagaggatc gttttaattc
      661 catccaatga ttttggtaag ttcttgaata atttacgtaa aaatacgatg acataaccag
      721 ctaagaatcc accaatcagt gcacctaaga atcctgcacc gcctgtatta gctaatgcac
      781 cagcagcaaa tccaacgatc aaaccagggc ggtcaccgat acttgaagca ataaatcctg
      841 ctaataccgg cagcatgaaa ccaaatgcag cttgtccgat ttggttgaac cagctagcag
      901 cttgattgta attccctaga tttgataatt gatcatgtgg cacgccaata aattggtcga
      961 tcatgaaaga aagcgcaata gcgattcctc caccaataac gaaaggtaac atgtgtgata
     1021 cgccgttcat caaatctttg taaattcttt gtccgatagt accatccgca tttccttctt
     1081 ctgaactgct ttcttttcca tcaccatgga atactggtgc agtaccacta agggctagat
     1141 tgatcaactc ttctggttta cggataccat cactgacagg acgattgatc agttcttttc
     1201 cgtcaaagcg attcatctct acttttttgt ctgctgcaac gattacacct tctgcacggg
     1261 cgatgtcttc agcagtcaat cggtttttga ttccttctga accgttcgtt tcgactttga
     1321 tctccacacc catttctttc gcttttttct tcaaagcatc ttctgccatg taagtgtgag
     1381 cgatccctgt tggacaagct gtaacggcaa caacgaattt tctttctgga tgagcagaag
     1441 cttctgcagc ttgtgtttct tgttctgctt tttcttctgc ttctttttgc tcttcagctg
     1501 tttggaacaa gtcttggact tcttctggtg tatttgcttc ttttaatttt cctacgaaat
     1561 ctgcatcaat cagcaatcga gatagtgctg ctaatgcttg caaatgtgtg tcgtttgcgc
     1621 cttctggagc tgcgatcatg aaaaacagat aagttggctg tccgtctaag gcttcataat
     1681 ctactccttt ttggcttttt gcgaataaaa ctgttgcttc tttaactgca ctgtttttcg
     1741 cgtgaggcat ggcgattcca tcaccaagac ctgtagaagt ttgtgcttcg cgggctagaa
     1801 ttccttcttt atatgtttcg atatcggaaa tccggccggc atcaaacatt ttttggacca
     1861 tttcatcgat tgcgcctttt ttatcagtcg cttgcaaatc catgatcatc gcttctttga
     1921 ccattaaatc cttgatattc atgattatcc tccttgaaac taatcaattt ttgtgatttc
     1981 aacttctggc agcaactcat caatcaattc gcgagctgcc aagtcatcag aaaaagctgt
     2041 tgcgcttccg caagcaactc cccatttaaa ggcttcgatt ggatctttcg tacggctgta
     2101 agccccaata aagccagcaa tcattgaatc ccctgcacct actgaatttt tcaatgggcg
     2161 aactaataca ttcgttttat aagttccttg ttccgtgaag agcaaagcac cgtctccagc
     2221 cattgagatc agcacattct gtgccccttc agctagtaat tttttcccat acggaatgat
     2281 ttcttctaca gattggaagg ttgtgttgta aagctcagct aattcgtgat tgtttggttt
     2341 gatcaacaac ggtttcttaa caagtgcatt ttttaggtca tcacctgttg tatcaatcac
     2401 gaaatctgca cctttttctc gaatgatatc aatcagttct tgataaaatc cttttcgcag
     2461 gctagctggc gcgcttcctg acaatacgac gatatctcct tgtcctactg ttcctaatgc
     2521 ttgcttcaac tcatcgattt cttcatctga aatagatggg cctaagccat tgatctcagt
     2581 ttcagtgtct gattttagtt tgatattgat tcttgtatct tcttttacgg ttgtgaacaa
     2641 agactggatt tgttcttttt caagccactt cgaaataaat tcgccagtga accctcctaa
     2701 aaaccctagt gctgtagatt gagaatcgat ccgtttcaaa atacgggaaa cattgatccc
     2761 ttttcctcca ggtaacttga agtcttcctt cattcggttc aaatcgccta gttttaaccc
     2821 atctacgcgt acgatataat caattgatgg attaagtgtt actgtgtaaa tcattgtatt
     2881 gcctccttaa ttgttgtctt ttcacggaat tcattaacga attctaatgg acaacgctcg
     2941 gttatgatcg tggctgcttc caaaggtgca acagaggtga aggacaactg gttgaatttg
     3001 gtatgatcaa tcaatacaaa tgtctcttcg gaatttttca tggctaaacg tttaacagct
     3061 gcctcttctg gatccggagt cgtgaatcct tgttcaagat gggcaccgtt cattcccata
     3121 aatgctttat taaaatgaaa attttttagt tgttctatcg cattagatcc taaaacagca
     3181 ttagttgcca gctttatcgt tccacctaaa ataatggtag caagctccaa atcaactaaa
     3241 tttgccgcat gttgaacgga atttgtcact actgtgatct gttttccttg cagaaaagga
     3301 atcatttcta acgtagtaga gccagcgtct aaataaatga catcttcgtc attaatggtt
     3361 tcagctgccg atttggcgat ttgctgtttt tcgtgaacgt ttttgagtga tttttcactc
     3421 atattctgct caaaattcaa taattgctct ttcttagctc cgccatgaac tctttctaga
     3481 aacccactat tctccagctc ttgtaaatca cgtcttatcg ttgattcaga agcattcaaa
     3541 aggtttacaa gatcttgtga tttcacgatt ttctgctgtt caagcaagtc taggattttt
     3601 tgtctgcgtt cctctgtaag cattttcacg atcacctcaa tacaaataat agcatatttt
     3661 ttttctacta gcaatataaa tcagtcaaaa acgttcataa aaattataaa tcagtcaaaa
     3721 aaaaataaaa aaccagtcag aaagactggt tttttatttt tttgtctatc atcaagccgt
     3781 tttatcgttt tttattttcg cttcttgttt ttttcatata aacagaagca ggttttcttt
     3841 ccttatgaag aagataataa taaagtccca tcccgccaaa catgaccaaa aaaccgatga
     3901 ctgatcgaat aggaaaatta ggaacaaaaa agagacagac ggataataat gatgccggaa
     3961 ccattattcg ataatagagt tgtttatcca ttttcttcac ctcatatttt ttgtaaagta
     4021 atcaattgtt ctaattctcg gtaatctaaa aattgcacac gcagatgctg ctcacctttc
     4081 ttgacatcga attggatact tcgccgcttt ttctttattc gtttgaaggt aacatcagag
     4141 agtctatgtt tgatttcctt taacggtaat tctgacaggg attctgaagg aacatagatt
     4201 cttaaggata aaagatactc ttgatatttt tcatctgtta cctctacttc tagatattcc
     4261 ctaatataat aacaataagc ttcgattcca ttatccaaag caacagtcgg atcgataact
     4321 ttatagcaca tcatgcgtga tcgattctcg tcaacccaag gaaaatacgc ctgagcattt
     4381 agtgttccgc gaacacgcct ttctttataa tctccttgtt ggatatcata actttttgtt
     4441 acaaaaaatg aagcattctt tttaggaaca ggttgcattt gtgcattctg atactggaca
     4501 gattggatcg tatggtcagt gtaaatgtat tcaacgaatg gcggtttcaa taaaccgaca
     4561 ccattgtccc aagcaagatg atcaaaccca agctggtccc taaaatagga ttgaaacatt
     4621 tgattgtttg gcttttgcca gttaaagggg tctcgataaa gctggataca tatgacttcg
     4681 ttttctaatt ccttcacttt ttctacttgt tggatgtcga gaaaaatcgg tttagggatg
     4741 atttgatgat aatagcgact ataatacatt tcccaacacg aagtgaaaca taaaccttgg
     4801 taaaaaagat cgtatcctgg aaattggttg caatcgacta ctacttcccc gttttgttgt
     4861 ttcattttag gtaaatgttc gatttcatcc tttttctcaa acaatagccg ttgagagatc
     4921 tgttttgtat tgtgatagat aaactcgcta taagctcgca tataggcgaa caccccatga
     4981 gcaatcattt ttttctgaat gaagtctcga atcaaaaatt gcttttcttt gaaaacagag
     5041 atagacaata cattttttat caataattga ttatcttcca agcgaaaact acattcgttc
     5101 tcgtcatttc ctacaactaa ccaactttcg tctcttaccg atgctagcat tattttttct
     5161 tgaagctttc gaagatcata cggatccgct tgttgtgtga aagagcggat aaatgttggc
     5221 tggatcaaca gacgtgtcaa aatagcccaa tcgcttattt cctgtttttt ttcttcttca
     5281 tttaagtctg tgagctggat agtcatcaat aatttatctt cgccaatcat tttctcacct
     5341 ctttcaaatc tttttataat ttaattataa ccaatgataa agaaaaacta aaactttatg
     5401 tcttagaaac caatttggac gattacatga tagactaagt aaaaagaaac aaagaggtgt
     5461 ttacaatggg gttgaaattt gaacgtacag ataatttaga taaacttttc gaatcatttg
     5521 ctgtcgatcc ggaaaaaaca gttgcaccaa aagaagagat cgatcgattt ctaaaaccac
     5581 agccacaaaa tgaaaagaaa aaagacaaga aacaaaagta agttaagctc aaaaaaagac
     5641 ttaccagcca aacttttatg aaagagtttg actggtaagt cttttttatt ctttttatga
     5701 ttcaattgct tgttcgattg ctgcccacgc ttcttctttt ccctgttttg taacggaaga
     5761 aaagagaata aacgtgtcat tgcgatcaaa atccaacgct tttttgattt cgctctcatg
     5821 cttgttccat ttaccacgag ggatcttatc tgccttagtg gcaacaacaa ttacagggat
     5881 atcataatac ttcaaaaatt gatacatctg gatatcttct tgagaaggct tatgacgcaa
     5941 atctactaaa gaaacgaccg cacgtagctg gtctctagtc gttaaatatg tctcgatcat
     6001 ctttccccat tttgctcgct cagttttgga tacttttgca tacccatatc ccggaacatc
     6061 gacaaaatgt aatgcgttct cgatcaaata aaaattcaat gtctgggtct ttcctggctt
     6121 accggaagta cgggctaaat tctttcgatc aatcaatgtg ttgataaaag aagatttccc
     6181 tacatttgat cgtcctgcca gagctatttc tggcaattgt gtatctggat attgttttgg
     6241 tgccactgca cttatgataa tttcagcttg atggactttc atggtctctc tccttaacaa
     6301 ggtgatgaat aaagcaagcg gctgtcgcaa aagccaaaat gacttttacg gcagcctctt
     6361 ttcatcaacc cgcttttttc tctgaatctt tatagattac tgttggctca ccagacaatt
     6421 cagctgcttc ttttgtgata atcacttttt cgatgttttc atttgaaggg atatcaaaca
     6481 tcacatccat catgatttct tcaatgatgg aacgaagtcc tcgagcaccg gtattgcgtt
     6541 cgattgcttt tttcgcaatg gctctcaacg cttcaggttc gaattcaagt tcggtattat
     6601 ctagagaaag aagtttttga tattgtttga ctagcgcatt tttcggctca gtcaagatcc
     6661 gtaccagatc atctgttgtc aatttctcta aagctgccat aacaggtaat cgtccgataa
     6721 actcagggat caatccgaat tttagtaaat cttcaggaat gatatgctgc atgacacttt
     6781 cgtcttcaga aagtttttgg ttttgtgtac caaatccaat cgtcttttcg cccatacgat
     6841 tcttcacaat cgtttcgatg ccatcaaatg caccacctac gatgaacaat atgttcgtcg
     6901 tatcaatctg aataaattct tgatgtggat gtttacgtcc gccctgaggt ggcacacttg
     6961 caacagttcc ttctagaatt ttcagcaagg cttgttggac accttcgccg gaaacgtcac
     7021 gagtaataga tacattttcg cttttacgcg caattttatc gatctcatca atatagatga
     7081 tccctttttc tgcaagttcc acattgtaat cagcagattg aagcaattta agcaaaatgt
     7141 tttctacatc ttcccccaca taaccagctt ctgtcaaact tgtcgcatct gcgattgcaa
     7201 aaggtacatt caatgttttt gctaatgttt gtgctaaaaa tgttttacca gaccctgtag
     7261 gtccgatcaa gcagatattg cttttttgca gttcaacatc atctgtgttt tcttgtgctt
     7321 gctgattgac acgtttatag tgattgtata cggcaacagc taacgagcgt tttgcgcgat
     7381 cttgtccaat cacgtagtta ttcaatactt caagaatttc tagtggttta gggacttcag
     7441 tgaattcgcg tacagcttct tcataaaatt cttcatcaat gatttcttta cataggtcga
     7501 tacattcatt acagatgtag acccctggac cagctacgat ctttttcact tcttcttggg
     7561 ttttcccgca aaaagaacag cgtacggtct cattgctact tggattgtca tacatggtct
     7621 tcacccctta acttgcaaaa agtatgcaag aaactatcaa agactttaca gtcttttact
     7681 atcataacat agtttagtaa aaagaaaaag tgtttaacaa aggatcaact gacctatacc
     7741 tttgcatttt ttactcttaa caaaaaataa ggaactgtga caaaatcgtg tcacagtccc
     7801 ttatttcgaa taaacaattt tctagaagta gcttcttcag aaatgattta ttacttgatt
     7861 tctattcttt cgcttctgtc gctgtacctg tgatcaattc gattgctttt ttcattgtca
     7921 catcatgttc cagcatatct tctgtcaaca cgcgtttgat ttgttcgatt ggcatgttgt
     7981 atgtttctga taattcttgg atttctgcat tgatttcttc ttctgttgct tgaagatttt
     8041 cagcagctgc aattgcttcg atcacaagat ttgttcttgt gcgcatttct gcttcacctt
     8101 cgaattgttt atgcaagtct tcttctgtag aaccagttaa ttgatagtac atttcaggag
     8161 agataccttg acgttgcatg ttgttcaaga attcgtccat tgaacgatgt acttcatcat
     8221 gaaccatcac gtgtggcaat tcaacgattt ctgcgttttc aacagccata cggatcgctg
     8281 cttcatcttt tgcatcgtcc gctgcttttt cttttgtttc tactaattct ttgcgatatt
     8341 tttctttcaa ttcgtctaat gttgatactt cgtcatcaac atcttttgcg aattcgtcat
     8401 ctaattcagg cacttctttt gcttttactt catggattgt cactttgaag actgcttctt
     8461 ttccagcaag atcttctgct tgataatctt ctgggaaagt tacatttaca tctagacttt
     8521 cacctgattt atgaccaact aattgatctt caaaacctgg aatgaatgag cctgaaccta
     8581 attcaagtga gtaattttcg ccttttccgc catcaaacgc ttcgccatct acaaagcctt
     8641 cgaagtcgat tactactgta tcgccatttt cagctgcagc atcttctttg ataactaatt
     8701 cagcttgtgc ttcttgttca cgtttgatac gtgcatccac gtcagcatct gttacttcac
     8761 ggtcttgttt ttcaacaact agatctttat attgtcctaa ttttacttct ggtttcactg
     8821 ttacttcagc agtgattacc cagtcttgac ctttttccat gctttcaaca tcgatttttg
     8881 gttgagaaac aggatcgatg ccagcttctt tgacagcagc ttcataagct tctggtaata
     8941 cagcattcaa tgcatcttca tataaagctt cttcaccgta catacggttg aatacttgac
     9001 gagaaacttt ccctttacgg aatccaggta cgttcaagct ttttttcact ttattaaacg
     9061 cagttgttaa tcctttttgg atttcgtctt gcgcaatcgt aaattttaaa acaccatcat
     9121 tcgtgccttt tttttcaaat gttgcagtca tttaattccc tccgagttta gaaattcatt
     9181 ttatacatca aaaacgtttc atgcatacct ttaaatagta cactaaccct ttcaaattgt
     9241 aaacatattg aatggataga atccttgttt ttcataacat ttttatcttt ttcactgata
     9301 aaatctaatg gaagaagatc atttgctgca aaattttttc tctttttttt aaaaaatctt
     9361 gtttttcatc ttctgtacct tcatacatcg tttttcctgt acacgcctct acagtcagtt
     9421 gaaaccagcg cttcgggtct tcgatgtatg tatcatagac aggataaaca attgcagatt
     9481 gcaacgtgaa ttcttctttt aacacggaac taagcagcgc atcttcattc ccgtaacgat
     9541 ctgaaaatac acataattgc tggtaacttg cctgctgctg cggctttggc agatcttttg
     9601 gtatgacttt gactaacttt tcttcaatcg tcaaatagaa aacttgatgg cattcgttca
     9661 attgcctaag tgtctccagt aattttgccc ttgctaaaat atggacctct ggcgatacaa
     9721 taagtttact cgctgtttgg ataaactcat gataaggaag ctgttcgatc tcatcaatag
     9781 acgcaagctg acgtgcaggt tccaacgaag gaagttcctc cgatttattg tggagtgcct
     9841 tgatcttctg cctctccatt tgtccggata attcttctgc aaattggatt ttttcaatga
     9901 cccgctgctc gaaagcttca taaaaatctg tacttgctat caattttcta gcatataaaa
     9961 aatcttgtgt actgattaac aagtcaaaat aaaattcagc aaactcctca ttttgaagat
    10021 actgtttttc atgcaagagt gcttgcttca atgcttcttt tttctcgtcc aactcgtaaa
    10081 gacaaaaaac aagcaggcta ttagcctcaa agctttcttt caactcgtaa gctcgttgaa
    10141 ataattcttt tgcctgctga tattgctggt ttgctagtgc ttgttgtgcc actcgcatta
    10201 aattctcata tttttctgga aaatcaatcg gcttcacgca gtgtcctcct cttgctcata
    10261 ttcagctcat gttcaatagt agcaaaacaa aaaaagcatg acaattaaaa ataactgaag
    10321 caccctctaa aagctagatt ttagatctga cttttagaag gtgctttcaa ctgttactgc
    10381 tttttattgc tcatcagctg ttgacttcct ggttgaacgc tttgatcaga ttgatcgtaa
    10441 caacacttgt attagtgaaa aaatcgccca gatgttgctt tttctgatta aagactgctg
    10501 gaagataccc taacatcagc aaaggaaatt ttagaatgaa ccggcaagca ccttctctaa
    10561 ctaaaacggt tgaccagcta agttcttctt catcaaagct gatgactcga ataccaaaga
    10621 tcattttccc aatcgtttgg ccatgattga atttcgtcaa taaaataaaa tacgctagat
    10681 aaataagtaa ggctgtgaat ccgtagagac tcagataaga atctgaaaaa ttaagccaac
    10741 ctagattttt ggcaatacca agtgttaaac gcgtaatagc tccgatacac aaaagatcga
    10801 ccaagaaggc aaacattcgg ataaaaaaac ctgcatagaa atacttagga aaatcatttg
    10861 cttttggcgg ttcatttctt gtgtccgtat actttttcca tttacgttgt ttctttttga
    10921 tttcttcggg cgtcaaaggc tctctttcaa aagagctcag taccttttgg gaaaagttgg
    10981 agtcaggtcc tacagcaggc tgctgttgct tatctttttc ttgttcctta ttttcatttg
    11041 aaagctctga catgcttact cacctccgta ataatacatt gcttttggtg attccgctgt
    11101 ccctagattc tcaagaacgg ataagatctg actagtctca gaaggcttca atccctggaa
    11161 ttctgctagt ttacttccta accatgtact agcaaaccca gatggcgtgg aagaatattc
    11221 tactagttcc gcatcttcaa gctgttgttc ctttcgtata gcttttaaag catcttcagg
    11281 aaatcccaat tcatcgacta aacctacttc ttttgcttgg acaccatcat aaatccttcc
    11341 atcagcaatt tttttgactt cttcttcaga tttattccgt ccctcgctga cgattgctac
    11401 aaaacgacta tatgcgctgt cgatatatgc ttgaagcacc gcttcttctt cttttgtctc
    11461 tggtcgcgtt cctgaaccca tatctttcaa cgctccgctt ttaactgttg tatcttccac
    11521 acccagtttt tctagaagtc ctgaataatt caatcctgac atgatcacac caattgagcc
    11581 ggtcactgtt tcttctgttg caaagatttt atctgcttga gcagaaatat agtagccacc
    11641 gctagctgcc atgtttttca tgctgacata cattgggata tcatgttctt tacgaatcgt
    11701 atccaatttc ttagcgattt ccgcactttc gtagacaccg ccaccaggag aatttacttc
    11761 taaaaagata cctttgactg ttggatcttc ttcaatcgcc ttcagttgtt ccataaaatt
    11821 tttatgattg taaccttcag aagcaaataa acctgaagac cctcccgcag caatcgttcc
    11881 atctactgat aattttacga ttttttgcgt actgtctccc tcttccaaca catttggagc
    11941 tagttcttca tccccatata accaactgtt caatccctca atttgatcgt tttcctgagg
    12001 cttagtcaaa ctagctgaaa ctaacgaaac cacaaataat cctgcagcaa tcagaactgc
    12061 tgcccaacgt cttttattca ttctttctcc tttctaatac aagtttttta tgacgatcac
    12121 agtttctgac tgctcagaag tgtcgaaccg ctctgctttt tcttcccgcg catacccgga
    12181 aaacgactct tttgttaatt catcttctac cgtaaactca cgagcttgag caacttccaa
    12241 ggcatcaggt gcgatttctt ggatgctatc ccagccagta tctaaaaata ttttcgtatc
    12301 atctgataca ccagctgatg cttcgaattt ggacaattgt ttttttaaca ttcccagtgt
    12361 catgatctca atttttgaat ccatttttac tcctcctcta tccgattact ttctattgta
    12421 ccgaactcct gaaaaagatg atagataaaa acccattatt ttttgacata aaaaggacat
    12481 ttgacaaaga atttgatata taccaattta ttttttattc tttttttgtt gacaagaaca
    12541 ttcgcaaaag gttatgattt taaatgtttc cagataaaaa acaaaaagga ggatagttat
    12601 accttttagg atagcgccag gtctgtgtaa acagatgacg aggagagggt ttatcgaaag
    12661 attcggcgga tggccctagg gactgcactc tacagaaaat ccacaaaaaa tgtctgcaaa
    12721 gataaaacaa aaggattttc ctgcagctgg aagcattcat acgaattcat tatagaaagt
    12781 aggatgtttt ttatgtgcgg aattgttgga atgattggat taaaaaatgt aacaccagga
    12841 ttgattgacg gtctagaaaa attagaatac cgtggttatg attcagctgg tatctttgtc
    12901 tcagatggca caactgatta tctggtcaaa gcacaaggca gaattcaaaa tttgaaaaac
    12961 aaaataaata ttgatactac aggaaatata ggtattggtc atacacgatg ggcaactcac
    13021 gggcaacctt ctgaagaaaa cgcccatcca catacttccc aaagtggacg cttcgtgctc
    13081 gttcacaacg gcgtaatcga aaactttgaa gaacttaaaa ttgcttattt agcaaatgac
    13141 cactttattg gtgagaccga tactgagatt atcgctcatc taattgaaac tttcgcgaag
    13201 gatactacaa cgcaagaggc gtttttaaaa gctttgcggg tcatcaaagg ttcttacgct
    13261 ttcgctttga ttgatcggac agcacctgat gttatttacg tcgctaaaaa taaaagtcca
    13321 ctattaatcg gactcggcga tggattcaat gtgattgcca gcgatgcaat ggctatgctt
    13381 gctcatacga aggaattcgt tgagattgaa gatgaagaga tggttaccgt cacatcagaa
    13441 aaagttatta ttcaaaattt tgcaggtgac atcgtagaac gttcttcatt cgaagcacaa
    13501 gtagatgctt cagatatcga gaaaggtacc tatccttttt atatgctgaa agaaatcgac
    13561 gaacagccta ttatcatgcg tcgtatcgct caaaaatacg taacagaaga caatcgtgtc
    13621 tctcttgatc aaaagctggt cgatacattg tctgatagcg atcgaatcta tatcgttgct
    13681 tgcggaacta gttaccatgc ggggttagca ggtaaacaga ctttggaaaa attgacacag
    13741 attcctgttg aggttcattt agccagtgaa tttggctata acacacctct tctttcaaaa
    13801 aaaccattct ttattttctt gagtcaaagt ggcgaaacag cagacagccg ccaagtgctg
    13861 gtaaaaatca accgtctcgg ctacccttca cttacgatta caaatgttgc tggttctact
    13921 ctttcgcggg aagcatcctt tacactgcta ttgcatgctg gacccgaaat cgcagtagca
    13981 tcaacgaaag cttatactgc acaaatagct gtactaactt tattagccaa agctatcggt
    14041 gataaaaaag aatttgaaac ttctcttgta ttcgatatca ctcatgaatt gagtttagtt
    14101 gctaatgcga tggaatcggt catcgcccaa aaagattatt tagaagagtt ggcagaagta
    14161 tatctcagcg atacaagaaa tgccttttac attggacgtg gtgctgacta caacgtttct
    14221 cttgaagctg ctttgaaatt gaaagaaatc agttatatcc aggcagaagg ttttgccgct
    14281 ggcgaattga aacatggaac gattgctttg atcgaagaag gaacaccagt gatcggaatc
    14341 atcagtgaag aagtgactgg tgcgcatact cgaggaaacc tgaaagaagt cgaaagccgt
    14401 ggcgctaaaa cactagttat tgtctcagag ggattagaaa aggaaagtga ccagctggtg
    14461 ctaccaactg tccaccctta tctaactact ctaaccacag tcgtaccgac tcaattactt
    14521 gcatattacg caacgctatt acggggattc gacgttgaca aaccacgtaa tttagcgaaa
    14581 tcagtgacag tagaataata aaagaacaag gaccagtgtc agacatctga cactggtcct
    14641 tgttctttta ttttttatga aaatatctct taatccagtc cgatttcttc tttgactact
    14701 gccgcgattt tatcgacata gtaattaact ttctcatcag taggcgcttc tgccatcact
    14761 cgaagtaatg gttctgtacc ggaaggacga actaggattc ttccttctga tcccatttca
    14821 gcttctgcct cttcaatcac ttttttgatt gccggaacat ccatcgcacc gtttttatca
    14881 cttacgcgga tattcactaa tttttgcgga tagattgtta cctctgctgc aagctctgat
    14941 aatttcttac ctgtctgttt catgatattc agtaactgaa ttcctgaaag catcccatct
    15001 ccagttgtgt taaaatctaa gaaaatcatg tgcccagact gctcgccgcc aaagttataa
    15061 tcgtttttgc gcatttcttc tacaacgtaa cgatcaccaa cttgtgtaac gacatctttc
    15121 aaaccgattc cttccaccgc tttgtggaat cctaagttac tcatgacagt cgtaacgatc
    15181 gtatcttttt tcaatcgatt tttttctgcc aagtatttag cacagataaa catgatttta
    15241 tcaccgtcga caatgtttcc aagttcatcc accgcaataa tacgatcgcc atcgccatcg
    15301 aaagctagtc cagcatctgc tcctttttca acgaccatct cagctaaacg ttctggatgg
    15361 gtagagccta cgccgtcatt gatatttaac ccgtctggat ttgtgcccat tgtataaaaa
    15421 tctgtttcaa gatcggcaaa caaacgatta acacttgttg aagttgctcc gtttgctgca
    15481 tcgacacaaa tggtcaaacc ggaaaggtca ccgttaatcg tttgtacaag gaattgagaa
    15541 tatttcaata agccttctgg aaattcttct acagttccca atccttcagc tgatggacga
    15601 ggcaattcat ccacttcagc atctaataat gcttcaattt ctagctcttg gtcatctact
    15661 agtttaaaac catctgcacc gaaaaatttg attccattat cttgtgctgg attatgagaa
    15721 gcagaaatca tgacccctgc gcttgctttt tgcaaacgtg tcagataagc aacacctggt
    15781 gtagagatca cacctagctg gaacacttcg atacccaccg ataaaagtcc tgaaatcagc
    15841 gcttcttcta acatttgacc tgagattctt gtatcccgcc ctactaacac gcgtgggcgt
    15901 tttccttctt cttcatgctg gcttaggaca taacctccgc accgtcccag cttaaatgca
    15961 agttctggcg taagttcctt gttggcttca ccgcgtacgc cgtctgttcc aaaatattta
    16021 cccatagttg taaaattact cctttaactt aattttctga ggaatttgtt ctgctcattt
    16081 gtgttgattc gcttgtttct gatgtttctt ctgtacttgt ggtcgagctg cttgtcccag
    16141 attccgaact ggaagaaatg gttgttgtcg atggttccgt tcctgaatca gcagatgaaa
    16201 tacttctact cgtacttgta ttttcttgtg tccgactgct cgtcgaagca gagctactgc
    16261 ttgacgtttg caacacgggt gtaatctcca cactaactga ttcgggcttg atacttaacc
    16321 cctcttctac tggtatttca attttacgag ttgttcgatg attgatacct gagacattga
    16381 tcggtacagc aatactgtca ccgatcgatg caagcaaatc gctagagccg cttacttctg
    16441 cttccagttt tgaaaaactg aaatcatagc tttctacccc ggcagctggt gttccttgct
    16501 gtatcccata aagtcgtacc gacttgcttg gcttgatcga atcagctctc actgttactt
    16561 gcactggatc agagacgata cttaatactt cccctgctgc attcagcgcc tgtattggga
    16621 cctcactatt aatcccatca tctgtgacca tcgaagcgtc cacatcagct actactcgtt
    16681 tgatttctgc caatgttttg tcacctgtag tgatagagac ttttttagga ctaacggaag
    16741 tatcatcaag ttcatatcca gatggtgtga acgttgaagg aatcaacgtt tccacatcga
    16801 aatcttttat tacctttttc tcaaccgtta ctgtaatagt cgatggttcg atctttgctg
    16861 tgacagcact gctcaaattt tgaattttta gcggaacttc atgtgttcct tcgcccagct
    16921 tagtgatatc tgctgtgacg cggaacatcc gtgtatcttc gtttgcctct gcattcaact
    16981 gaactcggtt tgcactggaa agtttgacag tcactgcatt ttcatatcca tggatatagt
    17041 agcgctttga atcataagaa atcttgatcg gcacccccgt aactgtttga ttatacgctt
    17101 catttccaga aagcgtattt ggaacggact ggccatttgc attgaagtac agcgcaatac
    17161 tgaacagcaa tgcaataaaa ctgtaaagaa tgcttgtccg tttctctttt gagatcattt
    17221 gcgatcccct cccttagtca taccgtctag gaaagattga atcacgtttt tcttgttttt
    17281 tgttttctct tcagcaatta gttctctacg caagattgcc aaatattctt gctgggataa
    17341 gccagccatc agttcattat ctaacgtgat gctgacgtcc ccggtttctt cagagacaac
    17401 gatggtaatc gcgtcactga cttcgcttat accgacagct gcccggtgtc gagtcccgaa
    17461 ttctttaggg atcaacatac tttctgatag aggaagatag gcgcttgcta ctgcgatctt
    17521 tccttctttt acaataactg caccgtcatg cagcggtgta ttaggaataa agatattgat
    17581 cagcagctcc ccagtgatat ctgcatctaa agcaatccct gtctcaatat actcatctaa
    17641 tccagtatga cgttcgatag tgatcaacgc accgattttt cgcttggaca tatattggat
    17701 ggctttgtca aaagacaaga tcatcttctc atcttcctgc tgttcgcttt ttgattgttt
    17761 gaaaagcgaa ctgcgtccaa gatgttccag tcctctccgg atttccggct gaaaaatcac
    17821 gatagcagct atcaccccgt acgtaatgac ttggttcatc agccaagaca aggtgtgcag
    17881 accaatgatt tccgctacga ttcggataac aataaaaata gctacacctt tcagaagctg
    17941 aatcgctttt gtgcctcgca gcagttggat cagtttgtat acaagatacc agacaaccag
    18001 aatatcaagt atgttcacca aaaaattcag agagaacaag tcaccggaaa acatttgctg
    18061 ccaatagtcc aaattaaaaa gttccccgat ttgaaatgac ataaaaagcc tctcttctct
    18121 tttgagattt cctctctagt atatcatatg ttttaatttt agaggctgat atgctcgtat
    18181 ttttcttgag aaaaacgcat aattttcaag aaaattgcaa gtatgcgttt tatttttctc
    18241 tgcaataaat atttttaaac ttcagagaat tattcattat attttttctg ttatttttcc
    18301 tttttttctt ttgtagcttg ttccattttt ttacgtcgtt ctgctctggc agctcttcta
    18361 gcagctcttc tttcttctgc ttcaaggtcc gtcgtttttt cttttctagt cttaacgggt
    18421 acatcgatag attcctctgg ttcaagtcgt ttcttgattt tttctaattc tcccgtcagt
    18481 gcagcatagt tgtaaaaacg tgttttagcg tcgtggacag tcttttcaaa taaagctttt
    18541 gcaagatttg gatttgcgtt atctagcgag gaaaagcgaa cttgtttcct catgaaatca
    18601 ggcatagcag agaaatcagg ttttttgtag tccaaagtca ttgggttctt gtttttttcg
    18661 accattgtag ggttatatcg atataatgac caataaccag aagaaacagc ttcttttgct
    18721 tctttaagcg attctttcat tccgccaagc aagccatgtg tgatacaagg cgtataggca
    18781 ataatcagag aaggaccagg atacttttct gcttcttcaa atgccttgat cgtttgcatt
    18841 tgattggcac ctgaagcaat ttgcgccaca taaacatttc catatgtcat cgccatcatt
    18901 cctagatctt tctttgaagc atactttcca ctagccgaaa atttagcgat tgccgaagct
    18961 ggtgttgctt ttgaggtttg accgccagta ttggaataga cttcgttatc caaaacaagg
    19021 atattcacgt ctgctccgct ggcaagtaca tgatcgatcc cgccaaaacc aatgtcgtaa
    19081 gcccatccgt ctccaccaat catccattgg ctgtttttta cgaatagatc ctttctcttg
    19141 tatatatcct ccagttcagg gaaaattgat cgttcgcttt cgatcgcagc ttgcagtttt
    19201 gctgctcttt gctgcgttcc ttcactctca aacatgtgta ctaaccagtc ttccatcaat
    19261 tctcgtagtt cttctgatac ttttggcaat acttctttga ttgaacttgc caaagcctcg
    19321 cgacgagtct gtgccgctag aagcatacca taaccaaatt cagcattatc ttccaataaa
    19381 gaatttgacc atgcaggccc ttgaccacat tcattggtcg tataaggaga agcaggagaa
    19441 gcaccgcccc aaatagaaga acagcctgtc gcattcgcga tcatcattcg atcaccgaac
    19501 atttgtgtca ataattttac ataaggtgtt tcgccacagc ctgagcaagc gcccgagaat
    19561 tcaagaagcg gttgattgaa ttgtgtagac aagacagtat tctttccttt gactggattt
    19621 gctttttgtc ttaatgtcat tgcaaaagcc caattcacag cttgttcttt ctgttcttca
    19681 taaggcttca tcactaaagc tttttctttt gcgggacaag cctctacaca cagaccacaa
    19741 cctgtacagt cttccactga aacttggata cggtatttta cgccgtctgc gcctcgcatt
    19801 tctctcacga taaatccttc tggcgcttct tccatttcct cttcatctgc taaaaatgga
    19861 cggatggcag catgaggaca aacaaaggca cattcattac acatcgtaca gcgatcacta
    19921 atccactcag gtacttctaa agcgacgccc cgcttttcca tagaagccgt tcctaaaggc
    19981 atttcgccag ttgtcattcc atttgctaca agtgtaccaa cagagagttg atttccttcc
    20041 tgtgcattca ctggttcaag tatttcttgt atataaccag tgttcctttt attgattttt
    20101 tcaggcatct ccaacgttct ccaatggtct gggatcgcga cttgatgaag cagttcggtc
    20161 gtccgatcga ttgcttgtat gtttttttct acgatagcca ttgatttatg tccatagctt
    20221 ttcagggctt cttcttttag cagcggaagc acctcatcaa aaggaatgat gtcagctaat
    20281 ttaaaaaaag ccgtttccat tgccgtattg atccggcgtc ccaaaccgac ttcttgggcc
    20341 aatctcatgg cattgatcgt atagaatcta atgttatttt cagccaagta acgttttaat
    20401 tttaagggca gatgcgtttc taattgttcg tcgctccaaa gagtattcaa taaaaaaatg
    20461 ccacctggct tcaatccttt gaccaagtca tagctatgca ggtaagctgg tgtgtgacag
    20521 gcaacaaggt ccgcatgctc gacaagatac gctgaacgta tcggcgtatc tccaaaacga
    20581 agatgagaga cagtcagacc gccagatttt ttcgaatcat aataaaaata gccttgcgca
    20641 tatttatcgg tgtgatctcc aataatcttg atagctgatt tatttgctcc aactgttccg
    20701 tcagatccaa atccccaaaa cttggcctgg aatgtttgcg gttctgtcaa atccagactt
    20761 tcctttggtt ccaaagattg ataagtcaca tcatccacga tccctatggt aaaccgtttt
    20821 ttgcgtatgc ttgggtcttt tttcaattca tcaaaaactg ctgagatttg gtcgggagtc
    20881 acatctttag accccaatcc gtagcgacca ccaataacag ccgggcgaag ttcagaatca
    20941 tataacgcac tttgaacgtc taataagaga ggttctccac ctgcccctgg ttctttactt
    21001 cgatcaagaa cagcaattgt ttttactgta tgaggcaact tttgcacgaa tgtttccact
    21061 ggaaaaggac gataaagatg gatattcaaa aaacctgttt tccgtccgtt tgcattcaag
    21121 taatcaatcg tttgttcaat cgtctgtgca actgatccca tagaaacaat gacttcttcc
    21181 gcatcgtctg ctccgtaata agtcaccaag tcataagaag ttcctcgtaa tcggttgatc
    21241 tctttcatat atttttgaac gatttcaggt aatttatcat aataggggtt gatcgtttcc
    21301 cgttgttgaa aatggatgtc tggattctgg ttcgtaccac taacagtcgg atgattggga
    21361 ttcatccctc gtttacgaaa tgaagctaat ttctcctgat tgatcagagg agctaattct
    21421 tcatattcca aaacttcgat tttttgaatc tcgtgactcg tacggaatcc atcaaagaaa
    21481 ttcaaaaaag ggacttctcc ttcaatagaa gcaagatggg caacaggtgc taaatccatc
    21541 acttcttgta cactgctttc agctaacata gcaaatcctg tttgtcttgc agccatcacg
    21601 tctccgtgat ctccgaaaat attcaacgca tttgtcgtca ctgcccgact agcaacgtgg
    21661 aaaacacttg gcagtagttc cccagcaatc ttgtacatat tcggtatcat caaaagcagc
    21721 ccttgtgaag cggtatatgt agttgtcagt gcaccagttt tcaatgatcc atggaccaca
    21781 ccagctgctc ctgcttcgga ttgcatttct actactttta ctggttgacc gaatacgttt
    21841 tcttttcctg ctgctgacca ttgatctact aattcagcca tggtcgaact gggtgttatt
    21901 ggatatattg cagcaatctc ggtaaatgca taagaaatat atgcggctgc cgtattgcca
    21961 tccattgttt tcatttttcg catgattcat catccttgtt catattctct cttattatct
    22021 gttccattat aacgtaaaac atgccatttt tttcttttat ttataaaaat attttacatg
    22081 tatctatttg aattggtcat ctaattttta gacaaacagt ctaaatcgtt gccttttttt
    22141 gtcagacatg tataaactat aagcgaaaga ggtgttttaa catggatata tcagtgattg
    22201 atgcaacgaa aacaaataca caaaaaggaa tcctttatgg ttcatcgaat gctcctaaaa
    22261 aaatggtcga attcatcaac ttagcttgtc cgtattgccg acaatggttt gaagaatctt
    22321 atgagctatt agaagaagca gtccaaagcg ggcaattgca gcgagtgatc aaattgttcg
    22381 ataaagaaaa agaaagctta cagcgaggga acgtgatgca ccggtatctc acaatcagcg
    22441 atggccaaaa agcgatcaaa gagatcaaac aaatattcga tactcaagac gagtggaaac
    22501 atctttctct ccaagaagta gcggattttg cagtagataa actaaagctg acagaacaaa
    22561 aagacgaaca gctgagccaa gctgtcatca acgaagctga gcaagcacat attcgatttg
    22621 ttccaactgt catcttgggt aaagaaatct ttgatgaatc tatttcaata gaggaattaa
    22681 aagaattgat ccaaacaaaa taaaaaaata aggagcgtg
//
LOCUS       DAZKCH010000044        22498 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000044 DAZKCH010000000
VERSION     DAZKCH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.044"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..334)
                     /locus_tag="ACG84X_001679"
     CDS             complement(<1..334)
                     /locus_tag="ACG84X_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HFP9127546.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKNDIILLKKEKEDLNDEINQKYDETLKNVYSSLIVSN
                     IEETSSSEI"
     gene            complement(425..877)
                     /locus_tag="ACG84X_001680"
     CDS             complement(425..877)
                     /locus_tag="ACG84X_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFP9127547.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(890..1300)
                     /locus_tag="ACG84X_001681"
     CDS             complement(890..1300)
                     /locus_tag="ACG84X_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9127548.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1575..1787
                     /locus_tag="ACG84X_001682"
     CDS             1575..1787
                     /locus_tag="ACG84X_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein-bridging factor 1 family protein"
                     /protein_id="HFP9127549.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1790..2002
                     /locus_tag="ACG84X_001683"
     CDS             1790..2002
                     /locus_tag="ACG84X_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127550.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            2142..2297
                     /locus_tag="ACG84X_001684"
     CDS             2142..2297
                     /locus_tag="ACG84X_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127551.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(2294..2518)
                     /locus_tag="ACG84X_001685"
     CDS             complement(2294..2518)
                     /locus_tag="ACG84X_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFP9127552.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2596..2784
                     /locus_tag="ACG84X_001686"
     CDS             2596..2784
                     /locus_tag="ACG84X_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127553.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2781..2954
                     /locus_tag="ACG84X_001687"
     CDS             2781..2954
                     /locus_tag="ACG84X_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127554.1"
                     /translation="MKKTDTLFIGFILGLLVIVAHQSIIGGSLFAALMVLINLLDSKE
                     RSNYGTRRSAKNR"
     gene            2923..3051
                     /locus_tag="ACG84X_001688"
     CDS             2923..3051
                     /locus_tag="ACG84X_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127555.1"
                     /translation="MAREEALKIGKVIADNRWGNSRPIILSKQHIEKQKAWQQIKK"
     gene            3110..3445
                     /locus_tag="ACG84X_001689"
     CDS             3110..3445
                     /locus_tag="ACG84X_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127556.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3678..4619
                     /locus_tag="ACG84X_001690"
     CDS             3678..4619
                     /locus_tag="ACG84X_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda-exonuclease family protein"
                     /protein_id="HFP9127557.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4621..5511
                     /locus_tag="ACG84X_001691"
     CDS             4621..5511
                     /locus_tag="ACG84X_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HFP9127558.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5554..6354
                     /locus_tag="ACG84X_001692"
     CDS             5554..6354
                     /locus_tag="ACG84X_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFP9127559.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6369..7220
                     /locus_tag="ACG84X_001693"
     CDS             6369..7220
                     /locus_tag="ACG84X_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9127560.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7286..7420
                     /locus_tag="ACG84X_001694"
     CDS             7286..7420
                     /locus_tag="ACG84X_001694"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127561.1"
                     /translation="MDELSQQESRMVRKISKLIIYRDTERFLTVLGNVYENPELLEVE
                     "
     gene            7421..7882
                     /locus_tag="ACG84X_001695"
     CDS             7421..7882
                     /locus_tag="ACG84X_001695"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9127562.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7908..8360
                     /locus_tag="ACG84X_001696"
     CDS             7908..8360
                     /locus_tag="ACG84X_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127563.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8466..8660
                     /locus_tag="ACG84X_001697"
     CDS             8466..8660
                     /locus_tag="ACG84X_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127564.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8691..8984
                     /locus_tag="ACG84X_001698"
     CDS             8691..8984
                     /locus_tag="ACG84X_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127565.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            8915..9454
                     /locus_tag="ACG84X_001699"
     CDS             8915..9454
                     /locus_tag="ACG84X_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFP9127566.1"
                     /translation="MVSEKQREFSSGEIGGHGSYKILILLFYNYPTTMSVIPQLEGEE
                     AIVNILENIDIKQTRKNARRLLKRYRNLERLVGPVKIDFSVMTVTKNLKFTIDSQNEE
                     IIEAISTRDSVIEALTRLSRIHFQVLYYSYCFPNKMSMYQIGEKLGYSDRTIERMKAV
                     ALVEFAEAYKSGELISRTK"
     gene            9529..9996
                     /locus_tag="ACG84X_001700"
     CDS             9529..9996
                     /locus_tag="ACG84X_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HFP9127567.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            10743..10973
                     /locus_tag="ACG84X_001701"
     CDS             10743..10973
                     /locus_tag="ACG84X_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127568.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            11132..11965
                     /gene="terS"
                     /locus_tag="ACG84X_001702"
     CDS             11132..11965
                     /gene="terS"
                     /locus_tag="ACG84X_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit"
                     /protein_id="HFP9127569.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11958..13373
                     /locus_tag="ACG84X_001703"
     CDS             11958..13373
                     /locus_tag="ACG84X_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFP9127570.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13385..14914
                     /locus_tag="ACG84X_001704"
     CDS             13385..14914
                     /locus_tag="ACG84X_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFP9127571.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14832..15884
                     /locus_tag="ACG84X_001705"
     CDS             14832..15884
                     /locus_tag="ACG84X_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HFP9127572.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15886..16203
                     /locus_tag="ACG84X_001706"
     CDS             15886..16203
                     /locus_tag="ACG84X_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127573.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16330..16953
                     /locus_tag="ACG84X_001707"
     CDS             16330..16953
                     /locus_tag="ACG84X_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HFP9127574.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16968..17858
                     /locus_tag="ACG84X_001708"
     CDS             16968..17858
                     /locus_tag="ACG84X_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 family protein"
                     /protein_id="HFP9127575.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17881..18096
                     /locus_tag="ACG84X_001709"
     CDS             17881..18096
                     /locus_tag="ACG84X_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127576.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            18108..18449
                     /locus_tag="ACG84X_001710"
     CDS             18108..18449
                     /locus_tag="ACG84X_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127577.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18449..18820
                     /locus_tag="ACG84X_001711"
     CDS             18449..18820
                     /locus_tag="ACG84X_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127578.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18813..19208
                     /locus_tag="ACG84X_001712"
     CDS             18813..19208
                     /locus_tag="ACG84X_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HFP9127579.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19210..19587
                     /locus_tag="ACG84X_001713"
     CDS             19210..19587
                     /locus_tag="ACG84X_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6838 family protein"
                     /protein_id="HFP9127580.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19588..20196
                     /locus_tag="ACG84X_001714"
     CDS             19588..20196
                     /locus_tag="ACG84X_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HFP9127581.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            20196..20537
                     /locus_tag="ACG84X_001715"
     CDS             20196..20537
                     /locus_tag="ACG84X_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127582.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20779..>22498
                     /locus_tag="ACG84X_001716"
     CDS             20779..>22498
                     /locus_tag="ACG84X_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HFP9127583.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFI"
BASE COUNT         8059 a         3307 c         4596 g         6536 t
ORIGIN      
        1 ttatttcaga agatgaagtt tcttctatat ttgaaacgat aagtgaagaa tagacatttt
       61 ttaatgtttc atcatacttt tgatttattt catcatttaa atcttctttc tcttttttta
      121 ataaaataat atcatttttt aacatagtaa tttgtttatt taaatctgat agtgtttctt
      181 ccttacttaa tataaatctt tctctatcat gtaatttatt tagtttttca tcattttttt
      241 gttctaattc ataagcttct ttttttattg tgttagcttt cgacagttta gtgattccta
      301 taattaataa aataagtcca atcaataata acattcaaaa ctcctcattt ctttgatata
      361 attattgtag agtttactca gaaatgagga aagagtccat gtgaaagcat gggctttttt
      421 atttttaatg ttgtaatact aaatgttcaa gattatgagg aagccctaaa tattcaataa
      481 tttggaactg actcatatca gataaatctt gttcatctat tgttctagtt aacatttcaa
      541 ttgcaaacat attagcttca gcttctatac cataaatcat acaactaagg ttgtttgctc
      601 taaaagctgc tgtgcaaata cctttatgga gtctaacgtg ggctatttca tgccataata
      661 caaatctttt catagaaggt gataggtttt gattaattaa tatcacataa catcttttat
      721 tgtgtatcgt ttgtcctaat gttttattcc ctaaatcagt ttcaattaaa tctatatcag
      781 aatatttgat tattttatat ggattaatcg catcagatcc aaactctaca aataattttt
      841 ctatttcttc taatatccag tatttgttta aatgcatacc aaagcccacc tattgacgat
      901 attttttagg agtgaatttt ttctttgctt taactttggt taaggcaagt gcaagttgaa
      961 tggcatcgta taatttttcc ttatcttcat cgtctaaagg ttcaccataa taatttgttt
     1021 cagcatctga attcaagcct tcaagtaatt tttcagcttg taaagcaata tcttgtttat
     1081 ctttttctgt taaatcataa taatggcgtt tatcagtacg tcctaaaaga taatcagttg
     1141 atacattaaa gtaatctgca actttttgta ttttatctcc agatggagta cttttattcc
     1201 atctagacat gcttccattt ccgaaattta actttctttc aagttctgcc aacgtcattg
     1261 aacgttcttt taataagatt tttatacggt ctaatagcat aggatatgca ttcctttcaa
     1321 aataccgaca aaaaaagtat ttttctgcaa attatctatt tacaaataga gaatttgcag
     1381 ttatactagt tttgtaagca agatatttac ggcatacaaa gactaaaagc aataaactaa
     1441 tagtctcccc agacatcagt aagctcgctt tttgtgcgct gtattttgta tgcttacata
     1501 atagcatatt tgcagttttt gtcaaactta ttagacaaaa atattagaaa atattcgata
     1561 agggggtatg aagcatgact ttaaaacagc aagtattaat tgctttagta aagaaaggtt
     1621 ggagtcaaag agagttagct cgacgaatgg gtatatcaat tacttattta cgagatatct
     1681 tcatcgaaaa aagaaaacct aaggaacgtt taaaacaaat cgaagaactt ttggatatca
     1741 agttagaagt agattctaat gatcagccat cagaacagga ggcgtaaaaa tggtacaacg
     1801 tttgagcaaa gcggagttta aagagaaata taagtattct gaaagtactt atcaaagaag
     1861 aatgaaggaa tttaaaaaat cacgttttag tgaggggtat aacgcagtta cttccaaaga
     1921 aataacaatt gatgtcgatt tatatgaaca gtttagaaca tggcgttcta aaaatcgatt
     1981 tagagttaga gctgtttgtt aatagctaaa aaatctaaat tcaccacttc tgaaaagagg
     2041 agttgctgct ctcctttcaa gtttgccaaa gtccacgttt tttcattttg gcaactcctc
     2101 ttcttggagg tggtgacggc gagagacgaa ggagggatga catgaaggaa gaatcaaaaa
     2161 tagggatttt gaatgagaac aattacacaa gattaattat tgaaacagaa gaagggaaaa
     2221 aagtagcaga agttacattg accgatgcaa ctcctgctga cggttatcgt attcgattaa
     2281 ctcctaaata tgattaacct tttggtgggt gtggatcgtt tccgtgacta tcacggcttt
     2341 gaatttttcc atctctgcca tgaataaata gctcagatcc ttgattttta gaaatctctc
     2401 tagcgatttt tactgcttct gattttgtat tagtatgtgc agtcgcttta gaatttccag
     2461 cacctttgac attccaacca ccattggaat taggtacaac atgttgattt tttcccatag
     2521 ttttcacctc catttctata gaaatatttt atcaaataga aatggagaaa ttcaataaac
     2581 gaaaggagaa gtgatatggc atataccttg caacaagaac atcaaattct cggtttgatt
     2641 aaacaacgca ggaaacaatt acaagatgac cgtgcagcgc ttagaaaagc cgatgagcta
     2701 tcagataggc aagctgaact aattgcttct gaacttgagg atttgagaat gctagaaata
     2761 aaaaataggg agattagatt atgaagaaga cagacacact ttttatagga ttcattttgg
     2821 ggttattagt gattgtagcg caccaaagta ttatcggggg aagcttgttc gcagcattga
     2881 tggttttaat caatctgctt gattcaaaag aaaggagcaa ctatggcacg agaagaagcg
     2941 ctaaaaatcg gtaaagtgat tgctgataat cggtggggaa atagccgccc tattatttta
     3001 agcaagcaac atatcgaaaa gcaaaaagca tggcaacaaa taaaaaagtg actctgccag
     3061 ccagcaaaga gtcacataca aatttataaa actaggagaa ttatatcaca tgaataagaa
     3121 aattgaaaat cttatcgaag aattgaaacg tgaatgccaa aagcaaggtg tttctattat
     3181 ttgtacagcc caaaaagaag gggaacttaa aagtctcgtt tatggtgaga caacagaaat
     3241 tttactttgt cttgctatgc aagaagaaca tttagatgaa aatctcccat tgtcagcaca
     3301 tattatgcgt agaattgctg tggatgctta cgaacaagcg aaaaatgaag aagaaaatca
     3361 accttcaaat catacttttg ttattaataa caaggaagat ttagctgatg tgatgactcg
     3421 tattctcaag ggggaatttc aatgatgaat gaaaaaacaa ttgatctact cattatttta
     3481 tttttcacgt tagtgattgt agcgaaaagt tatgtaatct ttggcttgtt attcgcaatt
     3541 accatgcttg tgctttgcgt gttagcaagc agaaaagagg ttaaacatga acgagttagc
     3601 aaatcttgac aactatttaa ctgatcctga ttatgctaaa ccaccatatg aagcaccaat
     3661 tgatgaggag gatgaagatg agtaaatcta ccttagaaat gagccatcaa gaatggcttg
     3721 aagaccgtaa gaaaggcatc ggaggttcgg atgttggaac aattttagga ttgaataaat
     3781 ggaaatctcc ttatcaacta tggctagaaa aaacaggaca agtagtactt gaagaatcag
     3841 gaagtgagcc cgcttattgg ggtaatgttt tagaagaagt ggttgctaaa gagtttcagg
     3901 aacgtacagg caaaaaagta cgcagaagaa accaagtatt tgaacatcca ttacatccat
     3961 ttttaagagc aaatattgat cgggaagtag tgggagaaaa tgccattctg gaatgcaaaa
     4021 cagccaatca atttctcggt aaagaatggg aaggcgaaga ggtaccgctt agctatctct
     4081 gtcaagttca acattacatg aacgttctaa acaaagacta ttgttacatc gctgtcttaa
     4141 tcggtggtca aaaatttatc tggaagcgga ttgaacgaga tcaagagctg atcgatacaa
     4201 tcactgaaca attagtagag ttttgggaaa caaacgttct tggaggtatc gagccaatta
     4261 ttgatggtag tcaagcgaca gctgatttct tgaaagagaa gtatgcagat gttgaagacg
     4321 ttcaaacgac gttaccaatt catttcgatg aactagttga acagaaaaac gaactcaaac
     4381 ggactaagaa agaaattgaa tcagctatcc gtcaagtaga caacgagatt atcagcgagc
     4441 taggtaaacg tgaagccagt atcggtatca ctcaaaaaaa catcatcagt tggaaatttg
     4501 tccgtacgag acgtatgaac tcgaagaaac tagcagagaa atatccagat gtcgcaaatg
     4561 atgaagagat ttataacgtt actgaatcaa gaaggctaac cgaaagggag atcaaataat
     4621 atggcaacaa atgaatcgtt aaaaaatcaa ttggcagcaa agccacagaa acaagttgca
     4681 ccaggtcaat taggacttaa agctttgatg aatacaccaa caatgagaaa gaagttcgaa
     4741 gaggtgcttc atgacaatgc taatgctttt atgtcgaatg ttatgactct tgtatctaat
     4801 gacagttatc ttgcagatag tgaaccgatg tctatcatga gtggtgcgtt aactgctgca
     4861 acattaaatc ttgggctaga taagaattta ggttatgcat atttagttcc attcaatagt
     4921 aaaaacaagc aaacaggaaa atgggaaaag aaagctcaat tcatgcttgg ctataaagga
     4981 tatatccaat tagcccaacg atcaggtaaa tacaaagcat taaatgtgat cgaagtttac
     5041 gaaggagaac taaaaagctg gaaccgactg acagaagagt ttgagtttga tccaaatggt
     5101 agaacgtctg atgaagtcat tggatatgtt ggctatttcg agttactgaa tggattcaaa
     5161 aaaactgtct attggaccaa acaagaaatc gaagctcatc ggattgctaa caataaagat
     5221 cgcgataaga caaagttaag tggtgtgtgg gcatctgatt acaatgcaat ggcacgaaaa
     5281 actgttttga gaaatcttct ttctaaatgg ggaatcttgt ccatcgaaat gcaagaagcc
     5341 accacatcgg atgagagagt ccaaagggtt caagaagacg gcagcattat tgctgaaaca
     5401 gaagttgaag aagatattcc tgaaagaaaa gaagcagagg ttatatctga agaaaatgaa
     5461 gatgtacaaa ctggattatt tgatgcatct aatccgccgt taaacaaata atgagggagc
     5521 tttctccctt gcttttctag aggagaaata cgaatgaaca caggatatgt caaattacat
     5581 cgaaaagtga tgaattcatt cgtttggacc aatccttata tgtataaatt atggaacttg
     5641 tgtttgatga aagcgagtca tgagaatcgc aagatacttt ttaatggaaa agagatacaa
     5701 gtgaacagcg gagaattcgt cacagggcgc gatgctatca catctgagat gaacgaaggc
     5761 gtgaaacgtg aacatcaagt gaacagcggt tctgtatgga gatggctaaa acaatttgaa
     5821 aaaaacggaa tgttgaacat caaatcaact acgaaataca gcgttatatc aataaaaaac
     5881 tggtctttgt accaaagcag tgaacaacaa atgaacatca aacgcacaac aagtgaacaa
     5941 caagtgcaca caaacaagaa tgaaaagaat tataagaatg aaaagaataa taaaacatca
     6001 tcgtcgcaac cacgcaaaaa gcgtgtttac gacaccgact cagtttacta cattctcgcg
     6061 gaggagttat tcaaacagat ttgtcagaat caggaaatca aaaagccgaa tctgcaaagt
     6121 tgggcagatg acattcggaa aatgatcgag atcgacaagc ggaccgaaaa ccaggtacgg
     6181 ggaatgattg aatggagtca gcacaatgtg ttttgggcat cgaatatttt atctgctaaa
     6241 aaattgcgag aaaaatacga cacaatggca gcgcaagcaa atcgtgatta taaaacaaaa
     6301 caaactaaaa cgcttgaata cgagaaattt agcacagatg agttgcctat ttgagaggag
     6361 gcgtaggcat ggaaactgtt ggggaaatca tggaaaagct gatacagaaa gtgcttgtcc
     6421 aacgtggcga atgtcctgaa tgcggacagc ctttgtatgg atggcgtacg aagaaccctg
     6481 atggctcaga acgttgtaag ccaacctgta tgcaatgtgg gtataaagca ttgcgagttc
     6541 aggaagactt acaaacagaa cgaatttaca acgagagcct gaaagcaaga gcaatcaatt
     6601 ttttcaaagg tggttctgtt gtgcctaatc aagcgttgtt tgattgcaca ttgcagaatt
     6661 atcaaattgt cgatcaagaa acaagacaag cggttgaagt aaccaaacgc tttgttaatt
     6721 cagtcttgtt aggaaatcca agtcaccttg ttttaactgg aaaacaagga acaggtaaaa
     6781 gtcacctagc gatggcagcg gcttgggaag tcttgaagcg atcaaactac gataaaaaaa
     6841 tcttatttat cgggttacag gaaatgctgg atcaaatcaa attttcgtac aacaatcctg
     6901 aactcagaaa aacgattgag ggatcgttga ttgcagatat caaaacagcg gatttagtca
     6961 tcattgatga tatcggttca gaactaggaa aagatgcatc agatagtcga gcgtttggca
     7021 taaacacgct aaattcgttc ttggatgcac gacagaacct agcaacgatt atcacaacga
     7081 acttgcttgg tgaagaactg aaaaaagctt acggtacgag aacaatatca agaatgtttg
     7141 tcaactctga tggatttacg atggtatttt ctcaaacagc agacaagcgc ataaaaccag
     7201 tcaaaggagc gatcgcatga atttgactaa acaagaaaaa agaatctgtc gtcagataat
     7261 gttgcaaatt ataggtgatc gtgacatgga cgaattatct caacaagaga gtcgaatggt
     7321 tcggaagata agtaagctaa ttatttatcg ggatacagaa agatttctca ctgttttagg
     7381 taacgtctac gagaatccag agttattgga ggtagagtaa ttgccaaaaa tattagatgc
     7441 atgttgcggt agtagattgt tctggtttga taagaacaat tctgacgtaa catttatgga
     7501 ttgtcgtcag cagtatgaag aattatcaac aggtcatgtg atcaatgttg atccagatgt
     7561 ggtcgcagac tttcgcgata tgccttttga agatgatgtg ttcgatatgg ttgtatttga
     7621 cccgccacac ttaagacatg tcggcgaaaa ctcatggctt gccaaaaaat atggaaaatt
     7681 agacgaactt tggccagaag acatcaggca aggttttgca gagtgtatgc gagttttacg
     7741 accttcagga acattaattt ttaagtggaa cgaggaacag ataccacttt ctgatgtgtt
     7801 agaggctatt ggagaacagc cattgtttgg taataaacga agcaaaacac attggcttgt
     7861 gtttatgaaa aaattcagct aacggaggaa acaaaggagg aaaagtaatg aagattgtat
     7921 taaataaatg ttttggtggc tttgggttga gccatgaagc aaaaatggaa atttttaaaa
     7981 gaaaaaatat tgaagtattc ccatacatca ataactttag ctatgactca gatgatgaat
     8041 acacgagata cacaggccaa aagctaggtt cgatggattt tatctactat ttcaaaaaag
     8101 acccgaaaat cgacaaagtt acaggaattt atagcgaaat tgaccgactg tacggaattg
     8161 ctgatgattc cagtttttca agtgattcaa acagaggtga taaggacctc gttgctgttg
     8221 tcgaaaaact aggaagtgag gccagtggac catatgcaag tcttaaagtc gttgatatac
     8281 ccgatggggc tgagtgggaa ataagtgatt atgacggcgt tgaaactgca cattatggtt
     8341 ttcaaacagg tagtatttag tccactaatg acaactaaag aggaggcaga aggatgagtg
     8401 aagatgaata ctttgaacag tagtctatta acgacagaga tttttaactg gaaaggggtg
     8461 tagtcatgga cgcatcggaa gtagtaaata aaattaatag tctcaaagag gttttcggag
     8521 acgtcgaagt agtgataaac gcacaaggct atgacaacga attttttaag cagattaccg
     8581 acattagcat tcagcaagga atggaagacg aagacggaaa ctttatcgat gaagtagcca
     8641 ttttagtgac ttgcgagtaa gtaattgaca gctaaagagg aggaagcgga atgaaactaa
     8701 aagacggatt ttactccagc ggccacggca tcggcggttt aatgctagat atgccgacaa
     8761 agaatcctaa aacacgtaag aaaccaaaat tcaaagtcgg tgacatggtt cgctgcgaag
     8821 cagaaggatt catctatcca tttcgtggat atgtagaaca cgtctataat cactcagcaa
     8881 tcattcgcat tgaaaacacg atggaatgtg ataagtggtt agcgaaaagc aaagagaatt
     8941 tagcagtggt gagattggtg gacatggaag ttataaaatc ttaattttgc ttttttacaa
     9001 ctatcctaca acaatgagcg ttattccaca actggaagga gaagaggcaa ttgtgaacat
     9061 tttagagaat atagatatta agcaaacaag gaaaaatgct agacgattac taaaaagata
     9121 cagaaattta gaacgtttgg tcggaccagt gaaaatagac ttttccgtga tgactgttac
     9181 caaaaatttg aaattcacaa ttgacagtca aaacgaagaa atcattgaag cgataagtac
     9241 tcgagattcg gttatcgaag cattaacacg gctaagtaga atccatttcc aggtacttta
     9301 ttatagttat tgttttccta ataagatgtc aatgtatcaa ataggagaaa aattaggata
     9361 ttccgataga actatcgaga gaatgaaggc agtagctttg gttgaatttg ctgaggcgta
     9421 taaatcagga gaactcattt cacgtacaaa ataaaaaaag tcggattcct ccgactatga
     9481 ataatatttc cgacataagt attatatcat aattggggga atcagaggat ggtacttttc
     9541 gatgtaaaga aatatgagac accaagcgcg aaagatgttg atatggaacg cacaaaacat
     9601 aatgtcgctg tgtttctttc agcatatcta tcagctagat gtagagtagg gcaacatcga
     9661 gaaccaaaag tgacagcatc ttattccttg gttccacctt ctacagctga tcatatattt
     9721 gaagcagaaa gaatgctgat cgataaagaa gaagcacagg aagaatttga gtatctgcat
     9781 aaattgtttg ttcgaggcta ttcagcgata cagcatccgc ataagcctga tgtgactgaa
     9841 aggcgcaaga agatattcta tgatcgttat atcaatggtc tgcccattta tgtaactgct
     9901 caaaggaata atactagcga agaatcggtt aaagtagaat caaacagaat tatcatccaa
     9961 tttgcttcat cgttagaact ggttgctttc aagtagccag tttttacact ttttataccc
    10021 ttttattacc aatttggttt ccattttata ccttttttat accaatcact tacctattca
    10081 acgttgtatt atgatagtgt cgaaaaatta ggaaacagga tcgacaaaat aaaatgtaag
    10141 ggaggaaatc tccctcatcg tttaattaag cttcgatagg cagcaacgga aatattaaga
    10201 ataaggatgt gaatttcaac tccttctaaa ttgttcttat tatctatcat ccgttgctgt
    10261 ctattgtttt tttaattatt cacacgataa ctaaaggtaa gtgaagagaa atgattccat
    10321 taataatttc aatttttgcg ctttgtctta atgtatatat gattggattt aaaaatgggc
    10381 aaaataaaaa atagtagcag ccaagaataa ttttatagtg tcactgtggc ggaaagggta
    10441 gacgctaagc atgtgtgcta ggtcaatgct tcggcaacca tgcaaggttc gattccttgc
    10501 cagtgacttt ggcaaccgag gcatcggcgg tttaaaaata taggggtgcg caatttcgta
    10561 cgcgttttgt gcatcgtgta ggttgctatt acataactgg ttaggttaga ttgagatttg
    10621 ggattcggta caaatgaatc gtcaaatgtc tcaagcacag gatcggaaac gtccctgcct
    10681 gtgcattaca tattagatca ctctttgagt ggtctttttc tttacataaa ggaggctaca
    10741 taatgagaaa ctactggtat gtatcgctaa ctaatgaata tcctcgaacc attgatgatt
    10801 gttcagtgcg tgttgtgcgt tctgtacaaa tcaaagggaa gtactctatt gtcgaaatgg
    10861 ggagagaagc agaaccatgt gagattgatg cgtgcaagct cgtttattgc ggtcatggtt
    10921 tctatgatga accaaacatt caaaataata ttaacaagaa tttgagggat tagaatgcaa
    10981 gaaatggctt aaaaatctcc aatcaggaca aatcaagtta gacaaagttt ccgatttaaa
    11041 gatattgatt gaagctgatt taatgctaaa agatattgaa aattagaaaa caaaactcaa
    11101 cctaaacaga atgtgaggtg gtgtgtattg aatggcaaga caacgtgatc caagacgtga
    11161 tgaagccaaa agaatttggt tagaatccaa cggagaaaag cagttaaagg aaattgcatc
    11221 tgaattaaat gtttcagatt ctcaggttag aaaatggaaa tcgcaagaca aatggagcgc
    11281 tgaattgatt agtaacgtta ccaatggcaa aagtaacgtt actaatcaag gtggcgctcc
    11341 tattggtaat caaaatgcta aaggtaacaa aggaaatagc cgagcttctc cgccagtggg
    11401 taataaaaac gctttgaaaa caggtgagta tgaaacaata ttttttgaca cgttaaccga
    11461 taatgagaag gacatctatt ctagtttgaa tgatgatcct tcttttgctt tgtccgaaga
    11521 aatacgactt cttaaaataa gacaacttcg aatgatgaaa agaatccaac aagctgaagc
    11581 tggactaaat gatgaagaag tcgaacgatt gcagcagcta agaaagatta aaactccgat
    11641 tgaaaaaaat ggtaaaaagc tagaaatcaa gcgtgaggtt atgcaagatg tgcagattag
    11701 cagaaaaaaa catcgcaaaa ttgatgatat tctttcaatt gaagattcat tgactcggat
    11761 tagcaaccag ttagctaaag ccatcaagca aatgaatgaa ctttatatga atgaatacag
    11821 aactgattta attaaagctc agactgataa gatccaagct gagacaaatg aaattggcgg
    11881 aaataattca ggtgaagaaa tagaagaatg gaaacaggca gttttaaatg ccgcaaacaa
    11941 acgggcggtg aaagaaaatg aataatgaat ttattccttt tgctgatatt ggttctgcca
    12001 ttgattatta ctatgataaa ccagtagctt tttgccaaga tattttgcat ttgaatcctg
    12061 atgaatggca agaaaatgtt ttaaatgatt tagctgaatt ttcaaaggtt tctgttcgtt
    12121 ctggtcaagg agttggaaaa acagcattag aagcaggagc aatactttgg ttcttaacgt
    12181 gtcgacccta cgctaaagta atagcaacag ctccgacaat gaagcaactt tacgatgtac
    12241 tttgggcaga ggtagctaaa tggttaaatg atagcttgat caaaaactta ctgaagtgga
    12301 caaagaccaa aatttatatg gttggtgatt cagagcgttg gtttgctacg gctagaacag
    12361 cgactaaacc agaaagtatg caaggttttc acgaggacca tatgttgatt gtggtagatg
    12421 aagcttctgg tgtgtctgat ccaattatgg aagctattct tggtacgcta tcaggttttg
    12481 ataataagct gttgatgtgt ggaaacccca ataatattga aggtgtcttt tatgattccc
    12541 ataattcaga ccgtgataaa tacagagttc ataaagtatc aagctatgat agtaaacgta
    12601 caaacaaaga caatatagaa atgattctta aaaaatatgg aaaagaaagt gatgttgctc
    12661 gtgtccgtat ttttggagaa tttccgaaag gtgcgttgga ttcatttatc agtcttgaaa
    12721 cagttgaatt ggctacagaa aaacaaatta gtgattcttt agtcaataaa acaaaggttg
    12781 ctcatattgg tgtcgacgta gctcgatatg gtgatgattc tacgattctc tttcctagaa
    12841 ttgctaccag ggcattggag tatgagaagt attcaaaacg tagcaccatg gaaacaacag
    12901 gatatgtcat caacatggcc aagaatctaa tgagtcaata tccgagtatt gataaagtga
    12961 tgattaaagt cgatgacact ggtgtcggag gtggtgtaac cgaccgccta gaagaactta
    13021 tagaagacaa acattatcct tttgaggtgt ttggagtgaa taacggttca acatcagaag
    13081 acgattttta cgataattta ggtactcaac tatggggaaa catcaaggaa atgttagaag
    13141 aaaatatgac agcaaatctt aacggagaac agcctgttat tgaattgcct tctgatagtt
    13201 cgttaatcaa agaattaagt actcgcaaat tcaaaatgac aagtagaagt cgtatacgtt
    13261 tagaaagtaa agatgatatg aaaaagcgaa atattggtag tcccgatatt gctgacgcac
    13321 tggctttagc gttttatgag ccaccaagtc actatcaatt tattcaattt taggaggtga
    13381 gcttttgatt agtacagtat tatctttaga gagatataag aagctacgtg ttaaatatgc
    13441 aacacaaatt gaagatggaa tgtttgatcc gaatggtttt atagaagata tgaaaccatt
    13501 ttttgctgat cgcgaaagaa aatatctagc ttatactagc gaaaagaatg aaatagataa
    13561 tagaccaaag cctaacactg atattgtaaa agttaataat aaacttcatg ctggtatgta
    13621 ttcaattgtc gtagaccaag cagtcaatca ttttactggt atacctatca aatgggatta
    13681 cgatgtatcg gaacaaaaaa gaacactcat tcaaagatta aaagataaat tcttaaaaaa
    13741 tgatatagaa cttccgacag ttccagaagc ttttaacaaa ttaacaagca atcttgattc
    13801 catgagattc gcaatgcttg attctgaaac tgcaactttt caaggagctt gtggagtagc
    13861 tttccgattg ctagagcctg tggaagaaga tgatggttgg aagttaagag caagtaatat
    13921 tgaaccttgg agagcagaaa gatatggaaa tgccggaatc tatatcaaag aaaagtatga
    13981 ctcttaccag aaaaaatttt ttcaagaaat gaaagttatg acaagaaata aaattctgac
    14041 atatgcttgc tatggtgatt tgaattttgt tacaagcgga acgttcaaaa aaattgatga
    14101 gaccgataac cctttgggga cgattacctt ggcagaattt aaaaataata cgaatcgtta
    14161 ttgtgatttt gaagtagctg aggaaattgg agatgcaatt gatcgtgctt tgtctgatca
    14221 acaaaacgaa atcgaacaat ttaagcttgc gtacatgctt gttactggca caacaatgag
    14281 caaaggcact gctaaagaaa tgatgaatca gctagggatt atcaacttaa aagcccctac
    14341 tgcaaaagct gaatatgtca caaaaaattt agcaaaagat ttcaatgaat atcatatgga
    14401 tctattgaaa aaacagtttt acaccatttg taaagcaatc gattttaacg atgaggtgtt
    14461 taaatcaaac agttctggag aagctcgcaa gtggcaaatc attagcctag aagcgaaaac
    14521 aaatactaaa gagcaatatt ttagagaagg attgaaagaa tgcgcagaaa caattgctgc
    14581 ttttcttaag tttcatgaca aagtagaaat tgagcctgaa aaaattattt ttactttctc
    14641 tagatctttg ccaactgatt taagttattt agctgaagct ttacctaaac ttgcaccata
    14701 cgtatccaaa cgaactattc agagccaaat tccatttgta acagatgttg attatgaaaa
    14761 tgaaatgatg gaattggaaa gtggaagtgc ttatccagat agtgaataca attttggcgg
    14821 aggtggcaat agtgacgata gaaacgaagt attggaccaa acgtcgagaa ctggaggatc
    14881 aagcaaggct caaacaagaa aatcagacac ttaaaaaatt aactagtgta tttcctgaag
    14941 cactgaaaga gatacaagca aaactattat cacaagctga cttacacaat atcacttatc
    15001 cagaaatgat ggagttttac agtacaagta atcagaaaaa atatcgtgaa tatgtggaaa
    15061 aaaattataa gtcattaaaa atgtatgatg caaaatacaa agagtttatc gatgaatttt
    15121 ttccaccatt tgactatgca aaagtcaatc gcttattaca aatacgatca gatgtattta
    15181 aaattcttgc agaatatgcg atggatgcag atgtgaatca atatttttct gatcgcttag
    15241 aggaaattct tcaaagaaca tattcttcta atgctaatgt ttttgttcaa cttttaaacg
    15301 ttgatatacc aaattattta ccagaaaatg aaattaaaca ttatttgaac tatccatggt
    15361 caggaaagac attttcaaga agactttggg gaaatatttc atcgcttgaa cagaaactct
    15421 ctaatgctat tgtaaaaagt gttgctagtg gagaaggcgt tatacacgca ttaaacacca
    15481 tgagattaga ctcagaaatt tgtgacatgt ttaagttaga agaatcaaag tataacaaag
    15541 cgatagaaaa tctcgttcga acggagtatg caaaatttgc acaagatggt attgaaaaat
    15601 catatttaga aacaggtatt gaggaataca acgtattgac tgcaaaagat gagagagttt
    15661 gccggatttg tggaggaaag gcaagtaaga atccctataa actgaaagat gctgtcatag
    15721 gtgaaaatcg agcacctttc catagtcgtt gtagatgtac ggatgttcct aatttaccaa
    15781 aattaggaaa ggatattgat gaagaatatg accgtttatt tggcgattta ttagatgagt
    15841 ttgcacatga ttcttttgga attaatttga aacggaggaa gtagaatgaa agattttttt
    15901 gaagcagtac taacaattaa tgtaaatgct gatattgcag aagcctacaa aacagctatt
    15961 gagtctgaga accatcctaa tggcttgaga gaccattgga atggcaatta tgcctacgtg
    16021 gttattggcg atcaaactgt taattatcaa gataatactc cagttgataa gaataccgtt
    16081 aatttaacga ttcaattatt atctcattca ttaccaaatt taaaagaaac agttgattgg
    16141 tatgaaaaga tgggatgtat tgttgttaga actgactaca aagaaggaaa gtctagtaat
    16201 taggcttttt tattttgtcc gaaatgacgt taaactagcg caatactggg cttggttgaa
    16261 tggtggggcg caactattaa aactcaaagc aatgcggggc gtgaaaacga atcgtggggc
    16321 gaaaggagaa tgagcatgaa acacaaatca ttaatgccaa tgaatttgca atactttgcc
    16381 gaaggtgacg atcaaaagtt ttcttttgat gacttcaaat cttttgtgga atccaatgaa
    16441 gaagctcaaa aatttattca gtcacaatct caaagtgttg ccgacaaaca attggaagct
    16501 tggaaacaaa ataacttaga taaaattaaa caggatacca tcaaggaata tgaggaatct
    16561 aagaaaaaca agtcacctga gcaaattcaa ctggaaaaac tacaagctga atttgaagca
    16621 gaaaaagcgt tgcgtgtgac aagtgataat aaagcatttg ttgcagaaca aattgctgga
    16681 ttagaactag atggagagtt aaaagagtct atttctcaat ttatgctaaa taatcttgtt
    16741 agttcggata cagatttcac taagaatgct gttgaaggtt ttacaagtgt tttgaatgca
    16801 attaatgaga aacatgcaga tgcattaaaa gaactacaaa tgaagtctgc atttggtgga
    16861 actcaacaat cgaataacca ggttcagcag aacaatgaaa cattaacaaa tccagaagaa
    16921 caattaggac aaattcttca acaatttaac taggagagtg aaaaattatg aaaaaaacat
    16981 ctttaaataa tttagagtat ttggatattt caccagcgat taatgctatg caagtaccaa
    17041 atacaccttt tttaagctat ttacttggtg ctggaaaaac agagccagca aactcgacag
    17101 aaattaaatg gcgtgaatat gatatcaaca acgatgattc ttctgaaaaa cttgagggcg
    17161 gagaatatcc agatgctgaa tcaggtcgaa cttggtttaa caactatact gaaattttta
    17221 gaaaatcaac ctctgtatct ggtacattag atgctattaa tgtgaatgga gtcggaaatg
    17281 aattaactaa tcaagtagca ctacgtggta tggaaatgaa aattgatttg aaccgaaaat
    17341 tgattactgg tgtaaaagct gatgaaaatg gttctaaagg tcgtcgaatg aatgggattt
    17401 tgaacttgat caattcagca aataaggcag aaacagccac tgcgggtgca gtaacaagaa
    17461 aagatatcga tactttattt aaattgatgt atgaaaaagg ttatatggga gaaaaactat
    17521 gcttgatttc tccagatatg caggagttaa tgactgatga gttagatgga aaatcaacaa
    17581 aaattgttca gttcggggaa agagtaactt ttggattgca aattggaaat atcgtgtcta
    17641 attacggtac aggtattgct ctactagaac catcattgcc aaaaggaaca attgccgcaa
    17701 tcgatactaa ttatgtgaaa ctacgtccat tacgtgaatg gagagcagaa gaacttgcaa
    17761 aaacaacgga ttctagacgt atcggtcttg taggtgaata ctctcttgaa tacaatgctt
    17821 caaactctgg ggcaatttta aatttaaagt ctgaataaaa gggagttagt actccctttt
    17881 ttgataggag gaattacagt ggtaaaaaaa gatgaaacta aaaaagatga agtcgtgaaa
    17941 tatagagtag gtaaaactaa aaattttgtt gggtttgttc atcctaaaac tcgtagattt
    18001 atcacagcag attcaaataa cgaatttatc atttctatag atgataaaga agcaattgca
    18061 attttggaag atgcaattga tgttaatgaa atttaggaag tgatctgatg gatgaatcgc
    18121 taaaaacgga aatcattgag tctacaaaag aagattttcc agatttgagt gaagaacgca
    18181 taactaattt attagaaata attttgctag aaattgaatc atacaacact tgtaaaaatg
    18241 atatttcatg ggaaaagtta aaaagcgtga ttagtgaagt gttgtataaa ataataaaaa
    18301 atgaatcaga aaaaacagta tcttcagtta gacgtggcga tacaacgatt agttatgctt
    18361 caacaacaaa tgatgttagt gagttacttc taggctatgg tgatttgata cgaagagtta
    18421 ttggttgtgg aggattggag tttttttaat gaatgaagca gatattttag aaactactta
    18481 tgaagatagt tgtattattg aaagactgac ggacattgaa gattctaata caaatattac
    18541 tattcaagat tacaaaaaag tatatgataa tcctatttct tgcgctcttt cacaaggtca
    18601 aatcgatgga ctagcagtca tagaagatgg agagatggta aatgtttcaa ctgacacata
    18661 taaattattt gttcatccta agattaaact aaaaaaagga gatcgaataa caataactca
    18721 aaaggccagt ggcttaattt tttctctatt tgctactaag cctttttact atcctagtca
    18781 ttgtgaagtg aatttgatag gaagtgagaa aaatgggtaa tctcaaatat gaatcaaatg
    18841 cagaaaagat cattgagaat tttaaaaata tgactgtaat tgctcaaaaa gaaggaatat
    18901 ccttcgttaa cgattcaatg aataaagtcg ttagtttagc taaaccatta actcctgtaa
    18961 aatcaggtaa tttaaggcga ggatatcgtg tagtaaaagc tagaaaacta tcaagcggtc
    19021 gaattgttgg agaagttata aacaatgaac attattttaa atatgtagaa gaaggtcata
    19081 ggactaaaaa tggtggcttt gtcaaaggga aattcatgtt aactcgtgca acgaatcttg
    19141 caaatatgtc ttatattcct cgaagattta aacaaatggc aataaaaatc gttaagaaag
    19201 gaaagtaaca tgaaagatga aatcattgct gcaatcagta gcaaattaaa agaaatctat
    19261 cctgatggga caatatatct tgattcagtt atgcagtcaa ctaaagattt ttatttcgtt
    19321 ttatcagtaa tggaatctgg aactgaaaat gtaggaattg atattcaaaa tgtttctttc
    19381 ttaattgata ttgcattgat tgataataac cctaatagaa atttaattaa tgaattagtc
    19441 tcacgttgtg ggactttttt taatacgatt acaatcgatg agcaaatatt atttccaaaa
    19501 gcctatttac ctgatgaagc agatggtgtt caacatattc gttttacatt agaatttcca
    19561 caatatattg aatggagtga aagataaatg ggagaaaaaa gaagtaaaac cggaattatt
    19621 tctgtcgaaa aacctacttg gtttcctttg gaagatgaga cagggaattt tccggtatat
    19681 ggtactgcgt tgccaatggg aacagcagta agtatcaaac caacagctaa ttatgaaaca
    19741 acacaagatt atggggattc agtggttcaa gatcaattta cagcttttgg tggtgcagaa
    19801 gttgaactgg aagcaaatgg atatactcat aaagttttat ctacaattac tggagggaaa
    19861 attgttaaag gtggtgcctt gcgttctgga gaagatattg cgcaagatgg tgcgtttgca
    19921 tatagacgta aaaaatcgaa tgggaaatac cgttatacgg tcttttataa aggacagttt
    19981 gctctagatt cagatgaaac atcaacgatt gaaggaagta aagtaagttt tactcatcca
    20041 acttggaagg gttcatttgt agatgtacca ggacttggat atatgtattc agttgatgaa
    20101 gatgatgaag gcgtggataa agcaatgatc ggaaattggt ttacaaaagt agcaattcca
    20161 attgaagaag cagaactttc aggaggtaca gaataatgtc aaaatatcaa acaacgatta
    20221 aattaacgaa aaaagacgaa gaaggtaaat atgagcaagt acaatttaaa tctgctgaat
    20281 ttttaccagg aacagttgta gaagatgctg caggagttat ggaagaaatg caaacagcga
    20341 ctgataagca atcagttaaa aaagctttaa gtcgtgctta ttcatttatt gcagatactt
    20401 tatttgaggg acaatttact ggtgaagatt attgcaaagg aattgatgct cgtgagattg
    20461 cctcattgac aggaaaatta ttgaagtctg ttactgcagg ttttgatgaa acttatacag
    20521 agacgaaaaa aaagtaagtg aggcgctcaa gtcaccttca tttaagtatt cgattactta
    20581 ccgagaatta gatataaaga cgcaattact cgaagcaggt tggacgttac cagaaattga
    20641 acgtactgac ttggatgagt taatgcgtct ttttgctttt agagatgcgg taaaagagca
    20701 tgaagatgtt gagtactatg ataatttcac tcaattttag gaggtgatac tttgaataac
    20761 gatgacctaa ttctgaagat gatactagat gaatctggtt ttactgccgg tatgaataat
    20821 gctgtcaaaa agttgaactc ttttgatgaa acaatcgaaa gaaaaagtag aaatagtggc
    20881 agttcattag gtagtatttg gaaaatattt gctggaagtt ttctagctag cggagtaact
    20941 agaatcgtag gagctggctt tgatctaatc aagggttcca taagtggagc ggttgatcga
    21001 gtagatacga tgaataacgc tctacgaaat ttccaaaata tgggatttag taattcagaa
    21061 attatgaaga atatcggaaa gaatgggctt ttatctcaag gtattcaagg acttcctact
    21121 gctttgaatg atgcgataag tcatgttcaa cttcttgctt cttctacagg tgatttaact
    21181 cgttcaactc aaatatttaa agctttaaat gatggaattc ttggtttcgg tggttcaact
    21241 gatcaagtta atgaagctgt tattcaatta tctcaaagtt tctcaaacgg aaaagtagac
    21301 gcacaaactt ggaactcaat gatcaacgct caacttggac ctactctttc tgctattgct
    21361 aaaaagatgg gaattacaat gggagatctg aaagaaggtt tatctcaagg taagatttct
    21421 gttgaagaat tccaaaatca attaatagaa atggatacca aaggtggcgg aggacttaaa
    21481 tcattaagtc aaatcgctaa agattctact aagggaatta aaacctctat acaaaatgca
    21541 aaaacagctg ttacacgtgg tgttggtgag gtaatagaag gattaaataa agcattagta
    21601 gattcagatt taggtggatt taagggaatt attgataaag tgggcagttc aatggaatcg
    21661 ttcttaaaag taattgctgc aaatattcct acagcagtat catttttaag taatttattt
    21721 aacgaaattc aaaaatttgg ttctgctttg aaattcatga tgccctttct tgttcctgca
    21781 gctaccgctt ttggagcgtt catgtttcaa cttaaaggta taccagcaat aataaaaagc
    21841 ttcaataatt ttaagaatgc cataattggc gttggaaatt cattaaagat tatgggggca
    21901 atagctgctg ctaatccatt tgttttaatt attggtgcag tcgttggtgc aatagctgtt
    21961 ttcggttact ttatggcaac caatgaagag cttagaaaca aggttatatc tatttggaat
    22021 gatgtgaaag attccgtaat tggtgtatta aaaaatataa aggactgggg aattgatact
    22081 tggaattctg ctaaagaaat ggcatcaaat gcagttgagg gtgtcaaaga tgcttggtca
    22141 ggaacaaagg aatggttttc taacacctgg aaaggtatta aggatggggc cacaggttta
    22201 tttgataaaa cagtagagac ttcaagaaat gcagtcgata gtgtaaaaaa tgcatggtct
    22261 aatatgaaga aatggttttc tgatacttgg caaagtataa aagattcagc cagagaaaaa
    22321 tggaatggaa tcaaaggttc tattatgtca gttgctggtc cattgattac aggtataaag
    22381 aatgcatttt tacatgttac tttttatcta gagaccttat ggaataattt agttgagatt
    22441 ggtaaaaacg tctttgagat tttaaaaaat gttatacttg cgccggtttt gtttatta
//
LOCUS       DAZKCH010000045        22337 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000045 DAZKCH010000000
VERSION     DAZKCH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.045"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(531..2027)
                     /gene="lysS"
                     /locus_tag="ACG84X_001717"
     CDS             complement(531..2027)
                     /gene="lysS"
                     /locus_tag="ACG84X_001717"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFP9127584.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="ACG84X_001718"
     CDS             complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="ACG84X_001718"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFP9127585.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="ACG84X_001719"
     CDS             complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="ACG84X_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFP9127586.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="ACG84X_001720"
     CDS             complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="ACG84X_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFP9127587.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="ACG84X_001721"
     CDS             complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="ACG84X_001721"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFP9127588.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="ACG84X_001722"
     CDS             complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="ACG84X_001722"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFP9127589.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8558..9028)
                     /locus_tag="ACG84X_001723"
     CDS             complement(8558..9028)
                     /locus_tag="ACG84X_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFP9127590.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9074..9499)
                     /locus_tag="ACG84X_001724"
     CDS             complement(9074..9499)
                     /locus_tag="ACG84X_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFP9127591.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9566..9835)
                     /locus_tag="ACG84X_001725"
     CDS             complement(9566..9835)
                     /locus_tag="ACG84X_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFP9127592.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9846..11441)
                     /locus_tag="ACG84X_001726"
     CDS             complement(9846..11441)
                     /locus_tag="ACG84X_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFP9127593.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="ACG84X_001727"
     CDS             complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="ACG84X_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFP9127594.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14994..15554)
                     /gene="pth"
                     /locus_tag="ACG84X_001728"
     CDS             complement(14994..15554)
                     /gene="pth"
                     /locus_tag="ACG84X_001728"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFP9127595.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15907..16881
                     /locus_tag="ACG84X_001729"
     CDS             15907..16881
                     /locus_tag="ACG84X_001729"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFP9127596.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17051..18451
                     /locus_tag="ACG84X_001730"
     CDS             17051..18451
                     /locus_tag="ACG84X_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFP9127597.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18529..19251)
                     /locus_tag="ACG84X_001731"
     CDS             complement(18529..19251)
                     /locus_tag="ACG84X_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9127598.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19330..19836)
                     /locus_tag="ACG84X_001732"
     CDS             complement(19330..19836)
                     /locus_tag="ACG84X_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9127599.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19959..21758
                     /locus_tag="ACG84X_001733"
     CDS             19959..21758
                     /locus_tag="ACG84X_001733"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFP9127600.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21826..>22337)
                     /locus_tag="ACG84X_001734"
     CDS             complement(21826..>22337)
                     /locus_tag="ACG84X_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFP9127601.1"
                     /translation="TEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTPEQPKPVT
                     PAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTGRDIGGWT
                     VPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESVKVGSVQW
                     FAPDFAVSM"
BASE COUNT         6177 a         4872 c         4033 g         7255 t
ORIGIN      
        1 agagtgtttc ccgattcatt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagcgattgt caactctttt ttaaaagttt ttttcgattt cgtttttcga aatctttcgg
      121 caactcattt atcataactt atcgtttgtt atttgtcaag aacttttttg aagttttttt
      181 cgatagaatc aagcttcgca agtggttctt ttttaacgac tcagttatct tatcatgtcg
      241 ttagtaacat gtcaataact tttttgttat gtttttgaat aaatattttc ttctgtcttt
      301 tggacaagta ataatatacc aactaaattt agcttggtca acgaattttt tgtatttttt
      361 caagtttttt tcaataaacg attattcata acttttcttt ctttatcgtt cgttttcgtc
      421 ttctttaatg tctagaatag tcggcattag cttttgaact ttcgttatta tttattcctt
      481 tctacacagc aaaagctgcc taaggaattc cttagacagc ttttattcga ttatctcatt
      541 gttgggaata gcaaaacatc ccgaattgat tgtgcatcag ttagcaacat tactaatctg
      601 tcgatcccga tgcctagacc accagttggc ggcataccgt attctaaggc ttccaagaag
      661 tcttcgtcta caccgtgagc ttcgtcattt cctagttcac gttctttttc ttgcgcttcg
      721 aatctttctc tttgatcaat tggatcgttc agttctgtaa aggcattagc aaattcgcgc
      781 cccactatga atagttcgaa tcgatctgtg aatcgaggat cttctggatt tttcttcgct
      841 aaaggcgaaa cttcgactgg atgtccgtat acaaacgtcg gttgtgtcaa tgtttcttca
      901 acaaatgttt caaagaattc attgataaca tgtccgacac ccatagcttc ggttacttct
      961 acattgtgtt tttcggctaa agctaatgct tcttccaatg tcatttcttg ccagaagtct
     1021 acaccagttt gttctttgat tgcatctacc atatggatgc gtttaaagtc actttctaag
     1081 tcgacagctt gtccatcata tgtgattttt gctgttccta gtactttttc agctgcgtta
     1141 cggataatac cttctgtcag attcattaca tcattgaaat cagtatatgc tgtgtatgct
     1201 tctaacatcg taaattctgg attatgtgta gtatcaattc cttcattacg gaaaacgcgg
     1261 ccgatttcat aaactttttc cattccgcca acaattagtc gttttaaatg aagttctagc
     1321 gcaatacgca aatataaatc aatgtccagt gcattatgat gcgtgataaa tgggcgtgcg
     1381 gcagctccac ctgcctcatt gtgcaatact ggtgtttcta cttcaatata gccattgcca
     1441 tctaaatagc gacggatttc gctgataatt tggcttcgtt tcataaatcg gtcaaagctt
     1501 tcgcgattac tgattaaatc caagtagcgt tgtctgtagc gttgttcaat attcgttaag
     1561 ccatggtatt tatctggcag tggacgaagt gcttttgaca aaatcgtgat ttctgaagct
     1621 ttgatagaaa cttcgcctgt gtctgttttc atgatttgtc cagttacacc aaagaaatct
     1681 ccaaggtctg catgtttgaa tacttcatag gcctcatcac ctacttggtc ttttcttaca
     1741 taaatttgaa tttggccttc acgatcttgt agatgcgcaa atccagcttt cccttttcct
     1801 cggcgagtca tcatacgacc agctacacta gcggtcaatc ccatttctgc tagttcttct
     1861 tttgttcttg gatcaaatag ttcatgcaat tcttctgagt tgtgcgtgcg ttcaaatcgt
     1921 tttccaaatg gatcgattcc atcttcacgc aattgttcca ttttttgacg acgtacaagc
     1981 atttgatcat ttaaatcttc tacttgatgt tgttgttcct gtgtcacaaa agttcctcca
     2041 ttctcatgtt aatctctttc ctataatgcc aatgaaacac aaaaaaagca agccgaactt
     2101 ggaatttcgg cttgaaaatt cacgaaaaac ttagaaatca caacgtttgt ttcaatagta
     2161 ctttttccgc tttttctaca aattgatcca gcaggtcatt gatttcttgc tgtttttctg
     2221 tctgattgat tgctactttc actttcgctg ctcgaggaat cccttttaaa taataagccg
     2281 catgtgttct gaattctcta caagctactt tttctccttt gagatctgct aagcgttgta
     2341 aatgaagttt agctgtagca attttttcgg ctggtgttgg ttcaggaatc agttcccctg
     2401 tttcgagata atgctgtgtg cggtgaatca tccatggatt gcccagcgct gcacgaccaa
     2461 tcatcacacc gtctgcaccg acatagtcaa gcatccattt tgcatcttct ggcgttttga
     2521 catccccgtt ccccataaat ggaatcgtca aatgtttttt cacttctttc aatacttccc
     2581 agtccgcttt tccttcatac atctgaaccc gtgtacgtcc atgcatagcg atggcacttg
     2641 ctccagctga ttgtgctgct aatgcatttt ctacagcaaa gacgtgctct tcatcccaac
     2701 caatacgcat cttgattgtt actgggatat ttactgctga agaaacagct tggaccattt
     2761 cgtatacttt ctcaggatct aaaagccatt ttgctcctgc ttctgctttg attactttat
     2821 ttactggaca gcccatattg atatctatta tatcggcagc tgtgttttct tcgacaaatt
     2881 gagcagcttc aactagacta tctttatttc cgccaaatat ctgtaaactt aatggatgtt
     2941 ctgtttcttc aatgtggagc atctctaaag tttttttgtt tctgaaatga ataccttggt
     3001 cactgatcat ttcacatacg actaagcccg caccaaattc tttgacagtg actcgaaatg
     3061 ctgaatttgt tattccagcc atcggtgcaa caacgacacg attagggatt tccacattgc
     3121 caattttcca tgtgtgttcc acttaaatcc ctcctaaggc ttctttcttc aatccatcta
     3181 attcttcttc gctatacttg tatttgttat tacagaaaga acaaaccgct tctgcaccgt
     3241 gatcttcgtc tatcattgct tggatttctt ctgcacctaa cgcgataatt gcttctgcaa
     3301 atttttcttt tgaacagtca catttgaatt gaacaggcat tttttccaaa atgttcaatt
     3361 cttctgtacc aagcaatcct ttcaatattt cttctggtgt ctgtccttca tctaagaggg
     3421 tagagattct tggtgtcgtt tttaattgtt cttcgatctt gctgattgtt tcttcatcgg
     3481 cacctggcat gatttggatc atgaatcctc ccgccgtctt gatgctgtcg tcagtattga
     3541 ccaatacact cagtccaaca gctgaaggga tttgttctga gatagcaaga tagtaagtaa
     3601 aatcttcagc gatttctcca gaaacaatcg gcgtttgccc agaaaaaggt tcttttaatc
     3661 ctaagtcttt tgtgacagta aacattcctt gtgttccaac tgctccccgc acatcgattt
     3721 taccttcact atttagagga agactgagat gcggattttt gatgtaacct ttcacatctc
     3781 cctttccatt tgcatctact acaattcctg ttgctggacc atcgccttgg attcgaacag
     3841 ttagtttgtc ttctcctttg agcgtcgcac caagtagcag actaccgacc aatgtccgtc
     3901 ccaaagcagc tgaggaggtg tgccaagtat catgacgtct ttgtgcctcc gctacggtat
     3961 ttgttgcttg aacggcgtat gctcggacga atccgtcgtg agcaagtgcc ttaaccaaat
     4021 aatctttcat ttgttatgta ctcctttttc cgtttttaaa ctcatagtga atcatactag
     4081 caactactgc ttttttcaac tttggaatgc ttcttttaaa aataattcag aatcatctag
     4141 aaaacaggac atcaccctat ttacaactta aataaagaaa tctcccgaaa accggttttt
     4201 gttccggttt tcgggagtca tatcagatca attgacctat atttttttat ttgtattgat
     4261 cgtctgaatg attatcttct gattgttgag aatctgaatc atgttctgct ttattttcct
     4321 cattcagttc atgttttgct tcttcaaaat cacgtttttc ttccgcttgt ttttcagcgt
     4381 ctttttcttc caaagcacgt tttgcttctt caaaagtttt cgcttctttt tcgcttggat
     4441 aatcatttga ctcagtacct tcaggcatca caccgtgttc aaacaatgac ttgattgctt
     4501 tggcatccaa tgtttcgaat tccaaaagtt tttcagcaat cagtttatgc tgtgcacgat
     4561 gagcttcgat gatttctcga gctttatcat gagcttccat caagattttt cgtacttctt
     4621 gatcaatctc gaaagcgact tgttccgagt aagcttttgt ttgaccatag tcgcggccaa
     4681 caaacacttg atggtttcct tcatattgaa caggacctaa acgatcactc attccatatt
     4741 ctgttaccat gcttcgtgct agagctgtcg cttgctcaaa gtcattggaa gcaccagttg
     4801 attggacatt gaagatgatt tcttcagctg tacgtccacc aagtaagcct acgatttgtt
     4861 caaacatatc ttctttcgtc atcaagaact gatcttcttt tggtaaagcg atcatatatc
     4921 cgccggcgcg tccgcgaggg atgatcgtta ctttgtggac gacccgagcg cgactcaata
     4981 ctaatccgac aatcgtatga ccagcttcgt gataagcaac catttcgcgt tcttttttgc
     5041 tgattacgcg atctttttta gctggacctg caatcacgcg atcttccgct tcatcgatat
     5101 cagaagcatc gattttcttt ttatttcttc tagcagctac taacgctgct tcattcaaga
     5161 cattttctaa atctgctccg gcaaaacctg gtgtctgttg agccacaact ttcaagtcaa
     5221 cgtcatctgc catcggttta ttccgtgcat ggactcgcaa gattgcttca cgacctttta
     5281 catctggacg tccaactaaa atctggcggt caaaacggcc tggacgtagt aacgctgggt
     5341 ctagtacatc agaacggttg gttgcagcaa tgacgattac tccttcattt ccgtcgaagc
     5401 catccatttc tacaagcaat tggttcaatg tttgttcgcg ttcatcatgt ccgccgccca
     5461 taccggcacc acgttgacga cctaccgcat caatttcatc aatgaaaatg atagctggtg
     5521 cgtttttctt cgctgtttca aacaaatcac gaacacgact tgctccaaca ccgacaaaca
     5581 tttctacgaa atcagaaccc gagatcgagt aaaacggtac tccagcttct ccggcaacag
     5641 cttttgctaa taaggtttta cctgttcctg gaggtccttc taaaagtaca cctgccggga
     5701 tacgggcacc taattcaaca aatcggcgag gatctttcag aaattcaaca acttcaacta
     5761 gttcttgttt ttcttcttcc gcacccgcta catcagaaaa acgtacgcga ttagcttttt
     5821 tgtctgcttc tttggctttt gatttaccaa agttcatgac acggccgcca ccgccaccgc
     5881 cgccgccttg ttgtcccatc atcatgtaaa agaaaaagat gatgattacg attggcaaga
     5941 agctaagcaa tagggaaacc catataccgc tgcttgattc ttcttttact gttgtagcaa
     6001 ctttgttttc ttttgccagt tctgttactt ggctcaatgt tgtatcattt ggcaaaatga
     6061 ttgttgtgaa atgggtagta gtcgtatctg ttgaacctaa gatagctaac ccaccgctgt
     6121 tagcgacggt ctgctgttct ttgtattcac cagtgatctt atatacacca tttgcaggct
     6181 gcacttcaaa ttctttgatc ttgcctgctt gtagttgttc tgtgaatttt gagtactcga
     6241 tatctgacga tcgctggccg ttattaccaa aaatgaaata aacgaccatt accatcgcta
     6301 agattacgag gacataatac aaggcatttt tcatcatgcc gttgttcttt ttgttcatag
     6361 ttgccctccc taagcgtcaa tttaatttaa cagtttttta tcaatcctga ccattctatt
     6421 gtaccataat ttaattgaga tacagcatta atttgattga taaacactag gtttcaatac
     6481 accgatgtac ggaaggttac gatatgcttc tgcataatcc aagccataac cgaccacaaa
     6541 ttcatttggt acgttgaagc caacataatc tgcttcgata tttactactc ttccttcagg
     6601 tttgtcaagt agtgtaacaa ttttgactga ttttgctttg cggtatttga aaagatccac
     6661 taaataagca agtgttcttc cgctgtcaat gatatcttca acgatcaaca gatcgcgacc
     6721 ttctacattc gtatctaagt ctttgacgat ttttacttcc cctgacgaga ctgttgcatt
     6781 cccgtagctt gaaacatcca tgaaatccaa ttccaaatac gtatcgatag aacgaacgat
     6841 atctgccatg aatggtaccg ctccttttaa gacacctact actaggggat tggtgttttg
     6901 gtaaatttct gttaactctt tgcctagttc tttgcaacga acttgtatct cttcttgtga
     6961 gatcaaaatt ctctcaatat ccttttccaa catcaggttc tccttccaat tgcttctttt
     7021 tgatatttgt aaagaagtat gtagtgtatt ttatcagttt cttcacgaat actcaaatat
     7081 gaaaaggcaa aaggtatcaa gctatatata tttcttttgg catctgtaat gatccaagca
     7141 tgctgccttt gtgaattagg tactttctga tcgataaaat atctagatac tttttttgtg
     7201 agattctctg ttaatttaat gcggtctcct gcttttcttt tttcgacata cagttgcaca
     7261 tcagcaggaa tccaaatgtc atgagaaaat agagaccatg aatctgttgc tttgatgtcc
     7321 cctgcatttt caggtttgac cagaccaatc cattctgttt cattcaaata tattccttgt
     7381 tctggaatca gcaacaagcg ctggtcttct gtctggctag ttgcttgttt ttctttttta
     7441 gagagtacaa caaaatgata ctctcttttc agtatccaat tattgccaat actgagttgc
     7501 cattggcttt ttttctgttg ccactggtct aaaatcgact ccatttgttg ttctttcaaa
     7561 ataattcctg tttttgagaa tgctttgtcg aaaaaggagt aaaaaaaata gtatcgttca
     7621 gcatctgtca tttcttcaat catttctgca gaaaatcgaa attgttcctc ccactgttcg
     7681 acttcctttt cgatcaactg tcccatatat ttttgaatga cttggtctgc ccattggatc
     7741 tgttgcgaaa attgctggaa atgtctcaac gcctgtgtat tttcttgttt caattgagga
     7801 actaccaaat gacgaagccg atttctctgg atatctaaca attggtttgt ctgatcctca
     7861 aagtaaacaa gctgcgattc cgctgcataa gtatataggt cttctttgct aaaactcagc
     7921 aacggacgaa tcagtctgcc cgtagcaaat ggttgtactt ctttgattcc agaaaaagta
     7981 tttaactgtc ccccacgaac gattttcatt aacaccgtct cgatttgatc atctccgtga
     8041 tgagcagtca tcaacgtgtc atattgtcct tcttccatca cgcgagtgaa ttcttgataa
     8101 cgaaagttac gagcttctgt ttctatggcg gatttggctg gatcttccca aatacttaca
     8161 tataaaggga gattcttctc ttcacaatat gagcgaagat aggcagcttc ttctgctgat
     8221 tcttctctta attggtgatt gatgtggacg atacctaaag aaaaaccgat ttggcgttgc
     8281 acttgtaaaa gtaaatggag caaaaccatc gaatcaacac cacctgatac cgctgctaaa
     8341 attctcgatc cttgttgcca gaatccttgt tcattcccgt gccgaataaa tgactgctgt
     8401 aatagcggtg cttttttccc gcctttttca acgttcatcc tttccacacc ctttcttcct
     8461 aaaaaaaaga gagcgggaaa acgtctaaaa cgacaattaa cctgccctct gttgatacta
     8521 tgacccaaat agtcgcacta tcattatttg cggcttttta gctgcgacgt ccgccacggc
     8581 caccgcgctt tccttctgtg tttcgcttca atgaagataa gcggtcatcg ctatctttca
     8641 aaaatgaact catcaatgaa tcgaagtctt ctttttgagc tgaaggttga ctgcgagaaa
     8701 aagatttttt ctgtgctgga cgatttcggt tgtcacgggg atctttttgt tgatattttt
     8761 taggacggct ttcttctcca gattcagcag gttgttcctg cgctttccgg atagatagtc
     8821 cgatttttcc atcatcattt actgaaataa ctttaactgt tacttcatct cctacactta
     8881 aaacatcatg gatgtctttt acatagccat ttgacacttc gctaatatga actagacccg
     8941 tttttccagc acctagatca ataaacgcac caaaatttgt gattcctgat acttttcctt
     9001 gcagttttgc tcctacctcg attgacataa aaaaaatgtt cctcctaatt atttcccttt
     9061 tttatattcc tgcttatttt gcagttgtag aactagttga ttgatctgtt tcatttgtcg
     9121 agctgtctgt atttgattct aatataggat aaactttttc accgtctttt gagtaaaaga
     9181 atttgcttct ggcaagttta gctacatact catcatcttt cagcaatgaa acatcttggt
     9241 gcagctgatc aacgtctgcg ttgacttctt tcatttcagt atttgcttcg actctcaatt
     9301 cgttcaattg atgcatcctt tgcatgtcat ggaaaatctg cacacctatt atcgcgaaaa
     9361 tgaccaaagc accaacaaaa attgcagcca gtctgcgtct tcgaaaaatc agttgacgtt
     9421 gttgttgctg aaattcagca tactttttct ttgcatattc cgtatctagc gcagcgattt
     9481 tattgctttt tttcgtcact tggattcgct ccaatctttt tgattgtctt tttcattata
     9541 ccaatatcgt gaaagcttgt ctaatctatt tctctagtgt ttctgtgcga ttttcagaaa
     9601 taatttcgta cattttttgt gcatcttctt ttttggttga ttcatgtaat tccgtaattt
     9661 tcacttccaa cgttttgttg ccaaactgga ctttcaaaat atcgcctact ttgacatcac
     9721 tggaagattt cgccaattta ccgttgattt gaattcttcc tttatcagct acttcttttg
     9781 ctactgatcg tcttttgatg attcgggaaa tttttaaaaa tttatctaat cgcatatctt
     9841 attcctcact ttttaatttt tttatttaat cgcaggattt tcttaccaaa aggcaacatt
     9901 agccattctc gtactgtaaa cagacgaaga cgaatcactg cataaatgaa cacagaagcc
     9961 ccgatcccaa ctcctatcac gctgacaaaa aaagcagtgg aacgatgagt tacaggacca
    10021 aatactatat tcaatacacc ataatacagc agcagtacta ctgtcataca aagaaggctg
    10081 aacatcaact tccgtccaaa atgccgttct ttccaaaaag catttagctc ttttgtttca
    10141 attcgaacaa aataccaaag cgtcacacct aatcctaaaa gggtagacag gcttgcacct
    10201 gctgttccta ataaaccggt cagaaaagaa gtagtcaatc cttttaccaa tagtccccat
    10261 cctgcgcctt ttaaagaagg gcgaaacgag ttcttgcttt gagcaatact ttgataagct
    10321 tggatgactg cagtgaaagc aatggaaaaa acaaataata caagcgctgc atttcccgca
    10381 taatctttaa acaacgcata attgatataa gggagcagca aggctaatcc caaagacgca
    10441 gctaatgcta aagcggtcgt caatctaaga tagattttgg ctgtctgtaa aaactgacga
    10501 tagatccggt tggtcaaatg acgagtcaac gcaggcagga atgtcgcact taatgcagtg
    10561 gcaatcacta aacctaattg tactaaaggc tgacctcgat catagacccc ttttgctatc
    10621 ttcgcaccgt attctgacag tccgtaaact tccaaagcat tttttacaaa gaaagagtcg
    10681 atcagctgga aaaagataag caatccacta taaatcgaaa ccagtccgcc ttctaccaga
    10741 aaacgccgga tcaagggctt tgacggctgt ttgaacaatg gaaaccgtcg gaagcttaac
    10801 gctcctccat gaatcttttg ttcatagtag tgaaggatcc catatgcgca taaaccgcca
    10861 aaaacagctc cactcattgc tgccgtccct gtttggtaca ccgtccatcc aagctttcta
    10921 aaagcaaacg cactacagac aatcacaaaa acacgaacga actgctcaac tacttgagaa
    10981 acagcagttg gttccatcaa gaatcttcct tggaaattcc ctcgataaaa agatagacca
    11041 ggcatcagca aaaaggtaaa ggaaactact tggatcagcg gtttcaattg tatgtctccc
    11101 atcatccaag caatccagct gctaaatgca aagacaaaca accacaaaaa gacacctgtc
    11161 caaaatacta agggataaag attttgcaaa gcttgctttc gctcgaaagg attctttctt
    11221 tctgcaacgt actttgatat gaactgcgga agaccggata aagctaaagt cattgctatc
    11281 ccataaattg gataaacttg ctgataaaca taaaaacctt cgtcgccgac taagttttgg
    11341 aggggaattc ggtaaagggc acttaatact tttgctatga aagaagcaat cgtcaataca
    11401 aatgctcctt gcatgacgcg ccgcatttct ttatgatcca aatcattgct ccttcctacg
    11461 ctgacagata tttttgctca cgcaacgctt tgacaaactt ttggatttcc tgaagccata
    11521 ctgcttcttc catttggttg gggatcgtca agcgtatcac catctgttct ttttcaacgc
    11581 ctagactggc ttttagtttt gtcgctgtca gtgcttcgaa taactgttcc acactatagc
    11641 gttttgttcc aactttactt agagtaaaga ctatatgcgc ctcctgtttc cttatcgttt
    11701 ctaggagcgc tcgatcgcca tccattttga tctgcccaat tgtcaagaga tgtgctactt
    11761 cttctggata ttctccaaaa cggtcgagca gatcatcttc tagttcatct agcatttctt
    11821 gcgaatcaag ttcacgaatt cgtttataga tctcgatttt ctgccgttga tctgccacgt
    11881 atgtttcagg tagatacgca tcgacaccga ggtcgatctc aacagtggtc ttctccactt
    11941 gactattctt tccttgttta cgagaaacag cttcgcttag catttgagaa tacatatcga
    12001 aaccgactgc atcaataaat ccatgctgct gagcacctaa gagattacct gcaccgcgaa
    12061 tggaaagatc ccgcatcgca atcttgaatc cagatcccag ttctgtaaaa tctttgattg
    12121 cctgaagacg tttttcactg acttcgttaa ggatcttctg ctgctcatac ataaagtaag
    12181 catatgcgac acggctgctt cttcctaccc gccctcgcaa ttggtataac gtggataatc
    12241 ccatataatc agcgttctca acgaacaacg tatttgcgtt cgggatatct actcctgttt
    12301 caatgatggt tgtagtgaca agaacatcat attgaccttc aataaattca aaaagcgtat
    12361 tttctaattg cgcctctgtc atttgcccat gagcataacc gatccgtgct tccggaacga
    12421 gttcttggat ttcttctact ttttgttcga tcgtttctac ccgattatat aaatagaata
    12481 cttgtccacc tcgtcccatt tctcgatgga ttgcttcgcg aatagcccca ggattttttt
    12541 ccataacata cgtttggatc ggataacgat tcgcaggcgg tgtttcgatt actgaaagat
    12601 cccgcacgcc taacatcgac atatgcaaag ttctcggaat cggtgttgca gtcagagtca
    12661 aaacatccac ttgtgcacgt aactgtttca atcgttcctt atgttttaca ccaaaacgtt
    12721 gttcttcgtc aatgatcagt agacccaaat cgctaaattc aatatctttt gacaaaattc
    12781 ggtgggttcc tacaacaata tcaacttgac ctgtacgcag ttgttcgatg gtttcttttt
    12841 gttgctttct tgttctgaaa cgacttaata gcccgatatt tacggggaaa ccttcaaatc
    12901 tttccagcat cgtttcatag tgctgctgtg ccaagatcgt tgttggaact aaaaaggcta
    12961 cttgtttgct ttcctttatc gctttaaagg ccgctcgaag cgctacttct gttttcccat
    13021 aaccaacatc acctacgagt agtcgatcca ttggtttttc tttttccata tcccgtttga
    13081 tctccgctgc acttctcaac tggtcatcag tttcagagta ggggaaggca ttttcgaatt
    13141 ctttttggta ggcgtcatca ggtccaaaag catatccttt ttctgactct cttgcggcat
    13201 ataatttgat tagatcgtca gcgatatcct cgatttttga agagactttt cgcttggttt
    13261 tcgtccattc acttccgcct agcttattga tgcgaggcgc tttggcttca gaggcgacat
    13321 atttttggat cagattcagt tgagtaacag gaataaacag tttgtcgtcg ttttgataca
    13381 aaatagtcat atagtcttgg tgaacgccat ctacttctag cgtttccatc ccaatgtatt
    13441 tcccgatacc atgattggca tggacaacgt aatctcctgc ttttaactca ttatagcttt
    13501 tcaatcgctc tgcgtttgtt actgtttgac gtctcgtttg ttttttcgtc gttttttgga
    13561 aaatttcttt ttctgtgata gctactattt tttcttgagg aagttcaaaa ccagcctgca
    13621 aagctccttc aactaattgt acctgtcctc tgatcaatgc atttttttct gtttctacta
    13681 ctaatatgtc ttcatctcga agcatttgtt ctgctttgcg tattctgtcc tttgtcggaa
    13741 taaagatcac aacagtctgt ttttgcttgc gccaacggtc catttctgtt ttcagcaatg
    13801 gcatttgtcc gaagaactgt tgcatcgtcc gatattgaaa attatggatt gcttggaaac
    13861 gaagatttcc catccctttt tggaagagtg agaaaaaggt tgtggtgaac ttttccttct
    13921 gcacgatttt ttgtatatct gctgaaaatg tctgctcaga aaacacccgc aattcgctga
    13981 ttttttgagt ctgccattct gccgcttccc tttcgatttc ccgatttgtt tccatgattc
    14041 gctgataatc atcaacgact agtaaactat ttgaagggaa ataatccaag atcgtcacag
    14101 attcttggta aagaagatct gagtagaatt ttgcttcttc tgtcgggaca cctgcttgcc
    14161 agcttgaagt cagctgaccg aagtaatctt gcaaaaactc gcggtctgct tcttctgtgg
    14221 tcgcagcaag ccgtttttct agcatttttt gcatttgctc tattccatgt tctagatcct
    14281 ctggtccgta gacttgttca ctcgttgggg aaacccagat ttcttccgtt ttttcgattg
    14341 agcgttgtgt ttctgcttca aaataccgca tagaatctat ctctacatca aatagttcta
    14401 cacgaacagg ataggttgtc gttaacgggt aaatatcgat aatgcttcct cgaatactga
    14461 attctcccgg ttttgcgacc atctcttctc gtacatagcc catcaaagtc aattggcgag
    14521 gaagattttc cacgtctatc tcatcaccaa tatgccaatt caattgcgcc tgtagccaag
    14581 ttttcttatt cggcagtcgt ttgtgcaaag atgcgactgg caacaaatag atacctgctt
    14641 ttttttcttg aagtgcgtta agcgttgcaa ctctctcgcc tcgcgcttct ggagaagaaa
    14701 aggccatttc agcagaaagc acttcatcca ctggaaataa atggatctga tcttgcggaa
    14761 tcacatgttg cagatcttct gctaactgat tcgcataata caaatttggc atcagaataa
    14821 tcatgttttt atttgttttc ttaaacgctc gagcaaatag aagtgttttc gctgagcccg
    14881 ctaatcctgt gattagttgt ctaggcattt tttcttctaa attgctgacc cattctttta
    14941 cttgcggatc ttttccgact aattgaataa tatccattcc ttttcctcct tcctcaattg
    15001 aatcgattca tcgcatccac gaacgaatgc ccttctatga gatattcgac tgctttaaca
    15061 gattgacaca tgctttcttc tatcaaaggc tgattttctt tgctgaaagg actaagcaca
    15121 tgctggacta ctgttttttt cccttctggc ctgccgattc ccaccttgat tcgatcaaag
    15181 acattcgtat tcaaatggga aataatactt ttgataccgt tatgcccgcc ggcacttccc
    15241 ttttgacgga gccggatttt tcccactgcc agatccaaat catcgtagat tacgactaat
    15301 tcctctggat aaatcccaaa ataagtcatt agtgggccga ctgcacgacc agattcattc
    15361 atgaatgttt gtggtttgac taaaaggatc ttttctccat tatgaaaaaa ttcggcaact
    15421 tctgcttcga acggattttt tttgaaagta gcttgatgct cgcgtgcaat tttatccacg
    15481 accataaagc cgatattgtg ttttgtatat tggtatttgg tacctgggtt tcctaacccg
    15541 acgatcattt tcatttttgt tttccaccta attctaaaaa gcagcacaaa aggctggact
    15601 gctaattagc ggtccagtcc atcgagcttt tttctttttt acacttgtca atgcatagta
    15661 taacacaaaa caaggcgttt cggctaaaag agaatcgtta ataaatgata aagaaattaa
    15721 aaatttcttc aaagtttaat gaaataattg atatataaaa atagtgaaat aacgcacatg
    15781 taagctttta catataatac aaccttgtta tctgttatat tttatagcca aatagcgtga
    15841 catggggctt gagaaatgtt agcataagca tgggaaaaaa caaatcaatg gaaggattga
    15901 tactaaatga ctgcagctgc agaaaaaaaa gatcatcaaa aagttattct tgttggagac
    15961 ggcgccgtag gttctagcta tgcctttgct ctagttactc aaaatatcgc tcaagaagta
    16021 ggtattgtgg atatcaatac tgctaaaact gaaggagacg caattgactt gtctcacgct
    16081 ttggcattta cttcacctaa aaaaatctat tctgctactt acgcagacgc acatgatgct
    16141 gacttagttg ttattacagc tggcgcacca caaaaaccag gtgaaactcg tttagactta
    16201 gtaaacaaaa acctaaaaat caaccgcgat gttgtcacac aaatcgttga atcaggattt
    16261 aacggtatct ttttagttgc cgctaaccca gtagatattt tgacttactc aacttggaaa
    16321 ttctcaggtt tccctaaaga acgcgtaatc ggttcaggta cctctcttga ctcagctcgt
    16381 ttccgtcaag cacttgcgga attagttgac gttgatgcac gtaacgtcca tgcttacatc
    16441 ttaggtgaac acggagattc agaattccca gtttggtcac atgcaaatgt tgccggcttg
    16501 caaatctatg aatgggtaaa aaacaaccca gaaatcgatg aagaagctat ggttaaccta
    16561 ttctttggcg tacgtgacgc tgcttacaca attatcgaga aaaaaggcgc tactttctat
    16621 ggtatcgcag tagcattagc acgtatcact cgtgccatct tagatgatga aaatgctgtt
    16681 cttcctttat cagtattcat gaatggcgaa tatggattga acgacatcta cattggtgca
    16741 cctgctgtta tcaaccgtca aggtatccaa aaagtaatcg aaattccttt aagtgacagc
    16801 gagcaagacc gtatggctgc ttctgctaag caattaaaag aaattctaga tgaagctttt
    16861 gctaaactag acgctgaata atctttgaac atgacggaaa acatctattc ggtgttttcc
    16921 gtttttttat tttatcaccc ttatggtttc taaatttttt cataaagtag agataacctt
    16981 cgtcttttcc tctaaattat gctatcatga gaccgttcca ccctaaactt ttacttaagg
    17041 agttgtcgat atgacaagat cttcgcatcg aaaaaaatcg aaacatgttg ctttgctttc
    17101 agttcttggt gttctcttag tgctgatcag cttttatacc tatcgcagta catactacac
    17161 aaagcatttt ttgccgaata cagaaataaa tggaataaat gtcagcaatc taacagtcga
    17221 aaaagcaaat gaaaaattaa aagaagctta ttctgataaa aaactggcta ttaaagaaga
    17281 tggaaaagtc tggcaggaag taccaaaatc cgagctcggc tacaaagatg atttcacttc
    17341 ggagctttct ccgatcctaa atgaacaaaa cggatggact tggggaatga cttatgtctc
    17401 agcggcagaa aaacaagaaa tagatcctgt cagtcaaaac caccaaaaac tagacactac
    17461 cgttcagaca ttgacaacta agctgactga tttgaacaaa gaccggacac ctactactga
    17521 tgcaacgatc gaaaaagcag gtgactcttt cgttatcaag cctgaagtca atggaaatac
    17581 gatcgacgtc gatgctgcgg tcaaacaatt aaaaagtgcg gtaaactctg gtaaagatac
    17641 aattgaattg actgaattca aagaaaaacc aaaagtaaca tctgaagaca gctcactgaa
    17701 agaacaactc gcatccatga atgctatcgc aaatgtaaaa gctacttaca gtataaacgg
    17761 tgagactttc cagatcccat caagtgatat tatgagttgg ctgacctaca atgatggaaa
    17821 agtcgattta gatacagaac aagtacgtca atatgtaaca gatttaggca caaagtataa
    17881 cacaagtacg aatgacacaa aatttaaaag tacaaaaaga ggagaagtta cggtcccagt
    17941 tggcacttac agttggacga tccaaacaga cagtgagaca gaagcattga aaaaagcgat
    18001 tctggcaggc caagatttta ctcgttcacc cattgtgcaa ggtggcacaa ccgctgatca
    18061 tccattgatc gaagatacgt atatcgaagt tgatctggag aaccagcata tgtggtatta
    18121 caaagacgga aaagtggccc ttgaaacaga tatcgtttcc ggaaagccaa ctacacctac
    18181 acctgctgga gtcttctatg tttggaataa agaagaagat gcaactttaa aaggaacaaa
    18241 tgacgatgga acaccttacg agagtccggt aaactactgg atgccgattg actggacagg
    18301 tgttggtatc cacgattcag actggcaacc tgaatacggt ggagacttat ggaaaacccg
    18361 cggttcacac ggctgcatca acaccccacc aagtgtaatg aaggaattat tcgggatggt
    18421 cgaaaaagga acgcctgtat tggtcttcta acaaaaataa tatataaaaa gaaagcaccc
    18481 gtacgattgg tacaggtgct ttctttttat tatctaacaa tgtgctactt acatttcagc
    18541 agcagtaaag acttctgaaa catcatcatc gtcttctagc ttatctacta gacgttccaa
    18601 ttgctctttt tgttcctcat ttaaatcaat cgtcgtttgt ggaatcatcg tcaattctgc
    18661 ttgcgccaaa gtgaactctt tttccaactc atctcgtaca gcagcaaaat cttctggtgc
    18721 agtataaatc tcgaatactt caggagaagt ttgcagatct tctgcccccg cctctaatac
    18781 atcctcaaac atcgtctctt catcaacagt caacccatcg cgttcaatag cgatatatcc
    18841 tttgcggtca aacaagtaac tgactgaacc cgtttctccc agtgatccac cgtttcgagt
    18901 aaaagctact cggacatttg tcgctgtccg attacggtta tctgtcaatg catggactaa
    18961 gattcctact ccacccggac catatccttc atacgtgatt tcatcgtaat tcgtttcatc
    19021 tacggcactc gtagcctttt taatcgcccg ttccacattg tcgttaggca tatttgcagc
    19081 ttttgctttg tccacaacaa gccgcaaagc tggattcata gatggatcag gaccgcctgc
    19141 tttagctgcc atataaattt cacgagaaag tttctgaaag actttccctc gttttgcatc
    19201 ttgggcattt tttcttcctt ggatattatg ccatttacta tgtcctgaca tgatttttcc
    19261 tcccttgttc ttttgagaat acacttctat tctagtacta tttcacaaaa aaacaaagcc
    19321 acagccaatc tataaacgct tcttgaatgc cgcaaaaagc acacataata tcacagcagt
    19381 cagagcaccg atcgaatcca acatgacatc ttggaacata ggtgttcgtc caccggtcat
    19441 catctgatgg aattcgtcca aacctgcgta ccctgttgct gaaagccaag caaggatcgc
    19501 tgtcagccac caaattttta gcttggggaa aacacctaaa aacaagctgc ctcccaaaat
    19561 aaaataggta ccgaaatgtg cgcccttcct taaaaagaac tctaaaaatt tggcgtagcc
    19621 cagatggttg atactcacca tacttccacc ataattaaaa cgtatacccg ctaatgtgtc
    19681 tttaaatggc tgattaggca gccagctttc taatcgcgaa acttgtgatt gctgtccgta
    19741 agtttgagaa gaactgtaaa ataagattat aacgactatc agtgcgatta ctaaataaat
    19801 atttccgttt ttcatttgtt tttttgaaga attcataagt cacctctgta ttttatctta
    19861 gacttttttt gaagaaacaa caatcatttt catagagact tcttccataa aaaagtgcta
    19921 tacttaattt tgtattacaa tatgaaggga gttttttcat gagttattca ttaaattgga
    19981 atctagattc tattttttcc ggaggcagtc attctgatgc tttgaaccaa cggatgaagc
    20041 aattggaaga ccaaatgaac gagtattatc accgcgtaac aaaatggtca cctagttctg
    20101 acaatgcaga gcagttaaac gctattcttc aattgcaaga aacgattacg aatggtttta
    20161 cccaatgcag cagctatatt actgcattgc tttctgccaa tgtcaatgat tcagatgcaa
    20221 aggtcttatc aggcaagctt tacgcaatgc tgcctcgtct gcaatcagcc gaaactgtat
    20281 tgtcaaagaa atttgcagaa atatctgaca atgattggaa tcagatgctt tctcaatctt
    20341 cgtttgaaac aattgctttt cgtttaaacg agattcgtcg tgatggctca caattattat
    20401 cagaagctga agaaaacatt ataaatacgc tttctttaga tggtctaaat gcttggagca
    20461 gtcattatga tacgattgta gccagcattt cgattccctt cgaacaagat ggacaagtag
    20521 tcgaattatc tgctggacaa gccttcaata agatgatggg cgatccagat ccaaaagtca
    20581 gagaaacact tttcgcagca tgggaagaag cctggaaaga aaaggcaccc ctcttcacgg
    20641 atactttgaa tcatttagat ggttttagac tttctgacta tgaacttcat ggtgtcacag
    20701 attttctaca aaaaccatta gagtacaatc ggttgaagaa agaaacattg tctgtcatgt
    20761 gggatacaat ccagaaaaac aaacaacccc ttgttaatta cttgactaga aaagctaatc
    20821 ttttcggtaa agaaaaaatg gaatggcaag atcaagatgc acctattatt ttaggcgatt
    20881 tgaaagaaaa aacctttagt tttgacgaag cagcagcatt tattatcgaa aactttaaca
    20941 aattcagtcc aaaaatggct aaatttgccc aatctgcttt tgaaaagagc tggatcgaag
    21001 cagaagatcg tcctgggaaa cgtcctggtg gttattgtac tgagttacca gaaacaaaag
    21061 aatcaaggat ctttatgacc tacagtaatt ctgttaatga ggttgcgaca cttgctcatg
    21121 aactaggaca tgctttccat agcagcacga tgtgggattt accttcttta aatcgcgaat
    21181 atgccatgaa tgtcgcagaa acagcaagta cattcgcaga actgatcgta gccgatgcta
    21241 cattaaaagt cgcaaaaaca aaagaagaaa aaatcaattt gctagataca aaactgcaaa
    21301 atgctttagc tatgttcatg aatatccatt cccgattcat ttttgaaaat cgattctatg
    21361 aagcacggca agaaggatta gtctcagaag ataagatcac agagatgatg gttgaggcgc
    21421 aaaaagaagg ctatcaagga gctttagcta cttaccatcc atatttctgg gctgcaaaat
    21481 tgcatttctt tattgatgac gtaccgtttt ataacttccc atacacattt ggctacctct
    21541 ttagtttggg catctatgct tacgccaacc aaaagggagc aaattttgaa gaagaatata
    21601 tccatttact acgcgatact gcctcaatga cgacggaaga tcttgcgaag aaacatttga
    21661 atgtcgatct tacccaacca gatttttggc aagcaggtat cgacatggtg actgaagata
    21721 tccaaacgtt catggaattg acagaagaat ttatctgatt tctattttat cacaataaaa
    21781 aaagagttag tccagaatgg gctaactctt tttgattaat cattcttaca tgctgacagc
    21841 aaagtcaggg gcaaaccatt gaactgaacc aacttttacg ctttcgcctg gttgaggagc
    21901 atggatatat tgtcctccgc ctaaagcaat cgctacgtgg taagttccgc cttgtgaccc
    21961 ccagaataac aagtctccag cttttgcttg agaaactgaa atttttgttc cagctgattc
    22021 ttgaggaact gtccaaccac cgatgtcacg accagttact tgcatgtaaa catagcgtgt
    22081 gaaccctgag cagtcaaagc cacttggatc tttaccgccc caaacatatg gagtaccaat
    22141 atatttgtaa gcttctgcta cgattgctgc accattcaca cttccagaag gagctggagc
    22201 aggtgttaca ggttttggtt gttcaggtgt tggtgttggc gttggagccg gagtactact
    22261 tcctgtgccg tttcctgtat caacactttg atctgttgat ggtgttgtag gcgcaggtgt
    22321 tgttgattct tctgttg
//
LOCUS       DAZKCH010000046        21994 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000046 DAZKCH010000000
VERSION     DAZKCH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.046"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..628)
                     /locus_tag="ACG84X_001735"
     CDS             complement(<1..628)
                     /locus_tag="ACG84X_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9127602.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFAL"
     gene            complement(777..1490)
                     /locus_tag="ACG84X_001736"
     CDS             complement(777..1490)
                     /locus_tag="ACG84X_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9127603.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            1665..3089
                     /locus_tag="ACG84X_001737"
     CDS             1665..3089
                     /locus_tag="ACG84X_001737"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9127604.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            3388..4095
                     /locus_tag="ACG84X_001738"
     CDS             3388..4095
                     /locus_tag="ACG84X_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFP9127605.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            4082..4405
                     /locus_tag="ACG84X_001739"
     CDS             4082..4405
                     /locus_tag="ACG84X_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFP9127606.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(4494..5531)
                     /locus_tag="ACG84X_001740"
     CDS             complement(4494..5531)
                     /locus_tag="ACG84X_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFP9127607.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(5852..6835)
                     /locus_tag="ACG84X_001741"
     CDS             complement(5852..6835)
                     /locus_tag="ACG84X_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFP9127608.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(7250..8020)
                     /locus_tag="ACG84X_001742"
     CDS             complement(7250..8020)
                     /locus_tag="ACG84X_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127609.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(8013..8948)
                     /locus_tag="ACG84X_001743"
     CDS             complement(8013..8948)
                     /locus_tag="ACG84X_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127610.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(9264..10913)
                     /locus_tag="ACG84X_001744"
     CDS             complement(9264..10913)
                     /locus_tag="ACG84X_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFP9127611.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(11030..13633)
                     /locus_tag="ACG84X_001745"
     CDS             complement(11030..13633)
                     /locus_tag="ACG84X_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFP9127612.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(13645..14694)
                     /locus_tag="ACG84X_001746"
     CDS             complement(13645..14694)
                     /locus_tag="ACG84X_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFP9127613.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(14720..15034)
                     /locus_tag="ACG84X_001747"
     CDS             complement(14720..15034)
                     /locus_tag="ACG84X_001747"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFP9127614.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(15050..15496)
                     /locus_tag="ACG84X_001748"
     CDS             complement(15050..15496)
                     /locus_tag="ACG84X_001748"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFP9127615.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(15497..17419)
                     /locus_tag="ACG84X_001749"
     CDS             complement(15497..17419)
                     /locus_tag="ACG84X_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFP9127616.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(17631..18527)
                     /locus_tag="ACG84X_001750"
     CDS             complement(17631..18527)
                     /locus_tag="ACG84X_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9127617.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(18520..19200)
                     /locus_tag="ACG84X_001751"
     CDS             complement(18520..19200)
                     /locus_tag="ACG84X_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9127618.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(19201..19983)
                     /locus_tag="ACG84X_001752"
     CDS             complement(19201..19983)
                     /locus_tag="ACG84X_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFP9127619.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(19976..20893)
                     /locus_tag="ACG84X_001753"
     CDS             complement(19976..20893)
                     /locus_tag="ACG84X_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFP9127620.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(21057..21311)
                     /locus_tag="ACG84X_001754"
     CDS             complement(21057..21311)
                     /locus_tag="ACG84X_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127621.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
BASE COUNT         6555 a         4512 c         3634 g         7293 t
ORIGIN      
        1 ataaagcaaa cgaggtaatc gtaataatga ttgggattaa tacattaaaa gactttaaaa
       61 cagcgggagg aatatttccg gatagctgaa tctgtagttt cttattatta gaaagtttaa
      121 taaataattc tgtagccgct aatccaacaa atatacctac aaacattcct gaagctcctg
      181 tataggatat aggtatcaca cccgtcactt caacagcttt atccgcattt tcaggagtaa
      241 acatcatctg cataggtgtt aatacaacaa atgtcgaaat agcaactaat accgctgcaa
      301 tatgatttgt ataatttctg cttgcacaca tatgataaga tactgctgct acaactaata
      361 atgtagttat gcttaatgta ccattggcaa ttgaagtacc aatttgttgt aacgtggtca
      421 atgtactagt atcgacaatt tcccccatga atcctgttgg ttctaagatc actgaattaa
      481 taagtgtcac aaatcctgct aacatcataa atggcataaa tgtagcaaac gcatctcgca
      541 aagttcttaa atggatctga ttccccaact tagtcgcaac tataccaaat ttttcaaata
      601 caatgtcctt cctgctactt ttgcccatat tttttctcct ttatgcttat tgtaatcgat
      661 tactttttcc acccaaataa tacatcactt atcaaaaaaa gtaaatactt ttaattaaat
      721 atatatatct tttttagtat aaaaaaataa gctctgaaaa aataattttc ccgagcttat
      781 ttttcaacaa aaacagcttc aaaaacaaag tcttgatata aatgtctcga taccgaatac
      841 tcgaaaggtt taccagacga tagagcaaca actttgtcta tctcaatcat aaattcacct
      901 ggatctattt ttaatatttt tgcgtcaaat tcattcgcag tatctccttt gatacgtatg
      961 tgcgaagtct ttatttccag acccagttca tttgtgatat aagcatatac agatttcttt
     1021 aaatgttttg gttccaagcc tggtatgact gctaatggca tgaatgtttg ctcaatcgag
     1081 tatggttgac aatcaataaa acggcttcgt acaatattat atacatagtc ttttacactg
     1141 atacttaatt tatcagctac ttttttcgat ggaagttcaa ttgagaaagt atggatttct
     1201 gaatctacgt gttcttcacc aaccacgcta aacaaacctt cgtttggacc aagaactcgt
     1261 gagttatcaa ttggtgttct gacgacttca gtcccatacc cacttctact tcgcaaaact
     1321 ccttcggaaa caagtaagtc tacgcctttc tttactgtta acttgcttgt atgataaata
     1381 actgccaatt catctcctgt aggaagtttc tcaccaattt tatactctcc atttacaatt
     1441 tttttcttta tatctaagta aatttccata tacttcgcaa tttttttcaa tggtgaccct
     1501 ccaatcaaaa acatatcttc atctatactt taacataaat aaaccgataa aatccacatc
     1561 aaaattatac acacaataaa aaagatatat atatttaaac aaaactattt actttaagtt
     1621 gtaagcggtg ttatcattaa gtggaaacag gaggtaaaaa aattatgaca actatgaaaa
     1681 agctaacttt tccagatgat ttttggtggg gttccgcttg gtcagctgag caagcagaag
     1741 gaaaaggaga aacaggaaaa gcagagacta tctgggatcg ctggtttaaa gaacaacctt
     1801 accggtttta tcaacgaatc gattcctcta ttacaaccga tcacatccat caatataaag
     1861 aagatataga actaatgaaa aaaactgggc ataactcctt tcgcgtttct atttcttggg
     1921 cacgaatgtt tccaaatggc ggtaccggaa aagtaaatcc caaagccatt tctttctatc
     1981 gaaaattatt ttccgaaatg aataataacg gaatcaaagt atttgccaac ttatatcatt
     2041 ttgacatgcc tgctactctt caagataaag gaggatggga atcacgtgaa gtagttgatg
     2101 cttatgttca ttacgctgaa acttgtttta aagaatttgg tgacttagtt tgtcattggt
     2161 ttaccttcaa tgaaccactt gggcctattt taggtactta tcttgaagat tttcattatc
     2221 caaacctcat tgactttaaa cgcggagcgc aagcagcatt cttcactata cttgcacacg
     2281 caaaagcaat acaagtattt aaagaactag ctcttcctag taaaataggc gttattctaa
     2341 atttgagtcc tacttttcct cgtagtcaaa atcctgctga tgtgaaagca gcagaaatcg
     2401 ctgatttatt ttatacgcgg agctttttag atcctatggt taaagggaat ttttctaaaa
     2461 agcttatcct gttattacaa gaatataatc agcttcctga agattatacg aaagaagatc
     2521 ttgtatgtat ctacgaaaat accgctcaaa ttcttggact aaactattac gagccacgtc
     2581 gcgtcaaatc tcgttcttct atggtggata catctagtcc atttttacca gagtggtttt
     2641 tcgaaccaca tatcatgcct ggacgacgaa tgaacgaata ccggggatgg gaaatttacg
     2701 aaaaaggaat ttatgatttg tgcatggata tcaagaacca ttatggaaac atcgaagcat
     2761 ttatctcgga gaacggaatg ggcgttgcgg atgaagaacg tttcatggat gatacagggc
     2821 aaataattga tgattatcgg attgagtata tcaaagatca tcttgcttac ttatggaagg
     2881 caataaatga aggatgtaac attaaggggt atcatctttg gacatttatt gattgctggt
     2941 catggatcaa cgcctataaa aaccgatatg ggctggtttc actcgacctt actactcaaa
     3001 aaagaacaat taaaaaaagt ggcgaatttt acaagcaatt aagtgataca aatggattta
     3061 gatacgatgt agacttgtta gttgaataat attctaaaat tccacttgaa gtgaacacat
     3121 tagaaaacaa gaataatgag aaataccaat aacaaatact ttttcttcat acttcattta
     3181 tacttgtcag tataagagac tgtgacaaat gtagtgatcc tcagaagtta ggtctggaaa
     3241 tctaacttga gaagattttt ttaaactacg tccagtcttt tttatttgtt taaaattgaa
     3301 gttgacaagt cttcattaaa aatttagaat attcacaagt ttgacgacaa ttatgaaaat
     3361 ttatgtcgtg ctaaaggagt tttgttattg gatgaaaagt tagatataaa aactgcgatc
     3421 aaagacacgt tacctaccgt ttttggttat atcggtattg gacttgcatt tggtatcgtt
     3481 gggaaagctg ccgggtttca tccgctggtc gtcacgttga tgtccctgct gatctatgct
     3541 ggttctgccc aatttatcac ggtcagcatg cttgctagcc atagtccact gctctccatc
     3601 gttctctcga cctttctagt caattcccga atgattctga tgagtatgac gattgctcct
     3661 tatttcaaga aaaatcggct gcttcaaaat ctgctgattg gcacattgct gacagatgaa
     3721 agtttcgcac tgggaatgaa taaattgaac tatactggac aaaagttaaa ctttcgttgg
     3781 atgaatacag ctaattggat ttcttatttg acgtgggtgg gttcttctct tgttggcgca
     3841 cttttaggga attttattac tgatccgaaa aagtttggtt tggatttcgc catcgtcgct
     3901 atgtttatcg ggttacttta tcttcaagtc atttctgata gaaacacctc taaacgatta
     3961 cagttgatcc tgattggtct cactttgatt ctggtatatg tcggactgat ttttatccca
     4021 agtaacttag tgattttagt tgtaacactg attgggtgcg gattgggggt gtggatcaaa
     4081 catgccttct tttgagttta cattgctgac tattttaggt tgtactttag caacttggct
     4141 ttctaggatc ctaccatttg tcttactgaa aaaattcgat ttgccgcaac cgttgcttga
     4201 gtatttaagt tttgtcccga tcgtcattat gtctgcttta tggttcagca gtctatttac
     4261 ccaaaatatc ggacatctgc cgcagatcaa tctcgaaaat gctttggctt cagttcctac
     4321 acttttagct gctattcttt caaaaagctt attggtgatc gtcttggtag gaattctttc
     4381 cctttcgttg attcgcttat tataaataaa aaaacaagag cttatggcaa attactgtca
     4441 tgcgctcttg tttttatcaa agtcaaataa gaaaaaaatc ggcgtattct tgcttatccg
     4501 ttgaacggac cactaacaac gacttttcct aatatatgtc ctgtttctac gtctttggtt
     4561 gcttgtttca agttcttcgc attcatccca tctgaataga ccttgctcaa tgtactgcgg
     4621 ataatccctt catttgctaa agcagcaatg tgcgctaaag cttctccttg cgtttcgatt
     4681 tcatagttat agtctgtttt agcgaacata tactcccagt cgaagctgat agattggttt
     4741 ttccaaacac ctatatctaa cggctctttg atccctacga tcgttcccac atgtccaaat
     4801 ggtcggacaa ggtgtttgat ttgatcaaag tagcgggtaa tatcgaataa tacagcgaca
     4861 tactctactt gatcgattcc taattcacga aaacttttac ttaagtcgtg atgataatcg
     4921 attggatagt ctacacctgt ttttttcagc cattcaaaat tcttcggact tgcagtcgcg
     4981 tagacttcta ggccagccca atgcgctagt tgattcaaaa tcgaaccgac gcccccagct
     5041 ccgttgatca ctaagatttt tttcccgcgg ttggcatttt cttctggagt cagaccaaat
     5101 ttttcaaata acaattcata agcggtcaat gaggtcaacg gcaaggctgc ggcttcttca
     5161 tctgaaagat tttttggtgc aagagcgaca atacgttcgt caaccagttg gtattcttga
     5221 ttgcttcctg ctcttgtcgt tgtacctgcg taaaaaacgc gatcgccgac agaaaatttt
     5281 tgcacttcat cacctacagc aacaactttc ccgactccat caaaccctaa gatacgtaaa
     5341 gcatttctta tcccgttatc ttggcgaagt ttcgtatcga caggattaac agatactgcg
     5401 ttgactttta ccagaagatc ccgtgaactg ggtacaggta tctgttcttt ttcatcaata
     5461 aagctttttg gatcatcgat cgacaaccct tcataaaaac cgactacctt cattaattcc
     5521 ttttctgaca tacgaattcc tccttagctt catcaagttg gagcatccat acagttttca
     5581 tttcaatata tatagtatgc tatttgttcc acttttattc atcataatta ttctcttact
     5641 taaagtaaac tatttgcact tttttggtta aaaaagaggt tgcgacaaga cttttgtcac
     5701 aacctctttt aaacggtgtt caatcaactg accctcggta ttcgctcaaa aaacgacaaa
     5761 atatgaggag ctatttttgt ttggctgttc ttattacttg atgcaggaca gctttttcac
     5821 gacctctaat tcacggtgtt caagcaagaa atcattgttc actgaaaagc gttggatgtt
     5881 ctttttcaaa ggtgtctaag atctctcgta cttcatcagt agatttcgta ttcatcaact
     5941 gaactcgcaa gtcatttgct cctggaaatc ctttgatata gattttaaag aaacgatgta
     6001 gtcctgtgat ggaacgcggg atgatttctg aataatgatc ttgcagatct agttgcagac
     6061 gaagtagtcc gatcagttct ttttctgtat gttccctcgg ttctttttca aatgcataag
     6121 gattcttgaa aatcccccgg ccaatcatga tgccatctac gccatatttt tcggccaatt
     6181 cttctcctgt ctggcgatct gggatatctc cgttgatcgt gatcagtgtt tgcggagcga
     6241 tttggtcacg taaagcaatg attttaggga tgacttccca atgtgcatct actttactca
     6301 tctctttacg cgtacgcaaa tggacagaaa gattggctat atcttgatga agtaggtgac
     6361 tgatccattc ttccatctca gacatttccg tatagccgat acgcgtcttg acgctgacag
     6421 gcaaaccgcc agctttagcc gcttcaatca attgtgccgc tacttctggg cgaaggatca
     6481 agccactgcc ttttccacgt tctgctacat tagggactgg gcagcccatg ttgatatcga
     6541 ttccttggaa gcccatttct gccatagcaa tgctcatttc tctaaaaaat tctggcttgt
     6601 ctccccaaat atgggcaacc atcggctgtt catcttctgt aaaggtcaat cttcctcgta
     6661 cactgtcttt tccatctgga tgacagaaac tgtctgagtt tgtaaactca gtaaagaaga
     6721 catccggtgc tgctgcatgc tttacgacat ggcgaaatac aacatctgtt acatcttcca
     6781 ttggtgctaa aacaaaaaaa ggctttggca gctctttcca aaaattagta gtcatttatt
     6841 tgttactctc cattctatca agcagtgaag tcgcaatctt tctcaaaaac attgtcatta
     6901 tactaggaaa caaaaaaaga agcaaagtga acagcttaaa agatgtttct gattgagcaa
     6961 aaaaagactg tgacaaaaat cttatcacaa ttccttttcc ggaataaatg gtgttcaaaa
     7021 gcttgcatct gcggtaataa gtccaaccaa acgaaaaata ggaggagcta tttttgtttg
     7081 gctgttctta ttacttgatg cagaacagct ttttcacaac ctctccacta aacggtgttc
     7141 aatcagctga ccctcggtat tagctcaaca aacgacaaaa tatgaggaac tattttcccg
     7201 tttgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttttc taacttctca
     7261 atcctcttcc tttattgatc aaataccaag taacggcgta caaaacaacg atgaatagca
     7321 caagtacgat catcgatgtt gctactggca catcgattgt tccaaggaat ccgtaacgga
     7381 aaccggagat catataaacg atcggattga ctttcgaaac agcttgccaa aatggcggca
     7441 acatagagat ggcatagaaa acgccaccta gataagttaa cggctgcaag acaaatgtag
     7501 gcacgatcga tacatcgtca taagactgag caaaaatccc gttgagcagt cctgctaacg
     7561 aaaacaagat tgccgtcatc aataatgtaa tgatgaccat gaaccatgaa tacacatgaa
     7621 gtggtacaaa gaacaaggaa atgatcgtta cgagagagcc gacgagaata ctgcgaccca
     7681 ctccgccaat cacaaagccc caaatgatca catgcgtagg aacaggcgct accaagattt
     7741 cttcgatgtt tttctggaat ttttgagaga agaaggacga agaaacgttg gcatacgaac
     7801 tagtgatagc agacatcata atcaaaccag gcacgatgaa ttccatatat gaaaaaccac
     7861 ccatgtcacc gatccgacca ccgatcattt ttccgaaaat aacaaagtac aaggatgtcg
     7921 tgatcacagg cggaaccagt gtttggaccc agatacgcaa atagcggttc gtttccttga
     7981 tagctaaact ttttaatgca gtaaaataaa gattaaacat ttttctcctc cgtatgatta
     8041 ttttcttctg tgattttcaa aaacagttct tctaaacgat tcgacttatt cctcatagaa
     8101 agaactttga ttccttgtct tgtcagctga tcgaagattc cgttcacccc ttgatttcgt
     8161 tcaacttcga cagcgattgt ctgttcatct tcaaatgtac aagcgtatcc ttcaatcaca
     8221 ggtttggtct catatggcgc taaatcaaag ataaatgttt caaattgcag tttggataga
     8281 agctctttca tactagtatt ctcgatcagt tcacctgatt ggatgatccc gatgttgcga
     8341 caaagcattt cagcttcttc taaataatgc gtcgtcaaaa tgatcgttgt accattttcg
     8401 ttcaattctc ggagaaactc ccacatctcg cgtctcaatt caatatcgac tcctgctgtt
     8461 ggttcatcca agatcagcaa acgtggttca tgcatcaatg ccctagcaat catcagtctt
     8521 cgcttcattc ccccggaaag catacgtgca cggacatttc tcttttccca aagattggac
     8581 tgcttcaaat atttttcgct gcgtttcatc gcttctttgc gagagacacc gtagtagcct
     8641 gcttgattca cgacgatttg ctggaccgtt tcaaagggat tgaaattgaa ctcttgcggg
     8701 actaatccaa tctgttgctt tgctcggact agatccgtat ccagatcata accgaagaca
     8761 ttcacttttc cagatgtttt attgactaaa gaagtaatga ttccgatcgt tgtagacttc
     8821 ccagctccat ttggtcctaa tagcgcatag aaatctcctt ctttcacgga aagatcgatt
     8881 cctcgcaatg cttcgacccc acttccataa acctttttca aattatttat ttcaagcgca
     8941 tttgccattt atttcctatc tccttataga catgattctt tattgtatca tggaatacag
     9001 cagatgaaaa aacaacttgg ttccagcgaa aaatcaggtt gctgggctca ggaaaatctc
     9061 ctaatgaaag acatcaatcg gacgaagtca gacaaccttt tcagaaaaaa caaatcgaag
     9121 ataaaggatt actattcata tgtgcaacaa aaggagcgtg agacaaaagt aaagaacact
     9181 tttgtctcac gctctaaaca cgtataaacg gcggaagcaa aagccaagat ttttgatcca
     9241 ataaatactt tcgatcactt cgcctatccc aatacatgcc actgccgctt ttcatcaaat
     9301 aacgcggctt ccgtttttgc ggtttctact aaagtctctg ggtaatccaa aactttcagc
     9361 aaggcaatcg catttcgggt ccttgaaggt ccttctttta atttgaaatc aaaactgatt
     9421 ccttttcctt ctgttacttg ttcttcaaag tggacattct cacaataatt ctttaaaatc
     9481 tctgtcaatt cgatatcatg tgtggcgaca aatgctaaag atggatactc cgcaagccac
     9541 cgaacgactg aagcggaaga agcaatccgt tcgatcgtat ttgtcccttt taaaatctca
     9601 tctacgaagc agtagcagcg ttctttggaa gccacttggt ccaacaaacg tttgatcgat
     9661 ttgatttctg aaacaaaata actgtcgcct tcaaataaat catcttcgat tgccatggaa
     9721 gtcaacacat gtccaggttg cagggtaaac tgttctgcaa tcgctgtttg gatcgtctgt
     9781 gctagaatac agctgatggc tatacttttg acatacgtag attttcctga tgcattggaa
     9841 cccgtgacta atgtattctt ctgccagttg accggattca ctaccgcttc ttttaacaat
     9901 ggatgataga tatctttcgc tgtcacaccg ccctcagtaa actctggtcg gcaagtgatg
     9961 ggcatataag tacggtaatt caatattgca gcggctactt ctaattctcc cagcaattcc
    10021 cacagcttga tggcttcagt tgaatgcttt tctaatttag tgagaacgaa atgataggag
    10081 ataaatggca gcatgaacat gatgttgaca tattcaaaaa tcaactctgc ttcactccca
    10141 ctcttcatac gaaatgaaaa acctaattta gggatgtctc ttaatggttt agtttgctgt
    10201 ttcagctctt cttgaagtgg tgtcggcagt tttgctagct gattggcggc tgaaatcgtt
    10261 gaaaccaaat aactcatgct attcagctct gtttctagtg tttgtttctt cactagataa
    10321 tagaccgtat tgaatactaa cccaccgatt gccaaataga ttcctagtac ttgtcctaaa
    10381 agaagcaaac ccaaacccac cagcggaagc aagccaagaa aaataaataa acctacgcgt
    10441 ccaatctttt tactttttcc atccgctaga tattgttttg caaaattatg atcttttttt
    10501 cctaaacgag cgaattgata ttggattttt tctctcagtt gaggattttc ctgataaaaa
    10561 gcaatcagtt tttctaactg ctgatcttca ccaaaatcaa agctgcgtaa acgttgatac
    10621 aacgcttctg aacctacact agaataggta ctgttgattc cttcgaatac ttcgaacata
    10681 tccaggtcat accaagtaag atcatcgatt tcgctatccc atgaacggaa cttcttctcc
    10741 gtgagccatg cttccttcaa gctttcttct ttatcaaatc tcggttgata aggaattttt
    10801 tcccatttgc tacgaactgt ttcctttaat ttcaaacgtg aaaaaatgtc taaagcaact
    10861 aataaaataa cagctgcaat aataattaaa acgataaatt ctctttgacc catatccctc
    10921 tccgttcctt tatttgttag ctttagtata gcactgttgc gctatttgaa aagagggtaa
    10981 aaaaacacct ttcaaaataa aaggtgtttt tttcttgtat attacatatt tatctctcat
    11041 ttatcaaaat tgacaaataa tcatagggag gaattgttgt taattcttgt ttattctcca
    11101 gtgcattgac aactgtccca agggaaagga tagcctcagg tactattttt tcttgttctg
    11161 ttggattagc taagcgaaga acaaatcctt gttcatgaaa ataagaagga taaatcgatg
    11221 atacaattaa gtcttcaggt aattcaatca atgaaaattt acgaggaaca tcaagttcat
    11281 tttgtaatgg ccaaatcttg ttatctaacc tgtgaataaa tacattcagt ttctgctttt
    11341 gataagaaat agattgttct aaccgttttt ctgcctgttt tgccactttg aactcattaa
    11401 atcttccttc ttctacatta aatccaaaag tgactttata ctcacctatc tcttgagcta
    11461 gcggtgtttc catcatgaca tgcccttcat ttgtcgtatc tcctgaagct cgcccaggtc
    11521 gccaagcaag attaggtttt ccaagttccc ctgttgttga aaataaggtt atgattaatt
    11581 gattttctat acgttcatac tcttttaaac catctgcata aaacgtaaaa taatgatcat
    11641 tttctgccac agagacactc ttatcgaata tttctaaatt aacaggtttc tctaccatag
    11701 tttctgacca attcggagga atgacatcag gggtattttc aataaatccg ttttgaattt
    11761 gtgcaattga tttttcagat ttatctaaaa cattaattgc taagcgcata cgatgcgagt
    11821 aaacagtatt atgaattttg agtgtgcctt caacgatttg actttctccc agactgaacg
    11881 atatttcata agatatttct tccatttcgg gtttttcaga taaacgatct tttaaatctt
    11941 taggaagttg agcttttccg taaacaacta atgtttcttg taaagaatct ttatatactt
    12001 tagctgtttc taattttaga gatagttctg tatctccttc taatggtgaa taatcatacg
    12061 tatcgccatc atttgctgaa tcgatcaaat gaacgaaatc aagatattgt ctatctccaa
    12121 ctatcaaatt caattgccca tctttaaaag aaagtttata tttattgtta cttatctcag
    12181 ttttgtctat ctcgattgct gtttctaatt tttcattatt tttctcaaat tcaacaacag
    12241 tgtatcctag tgctggcaca tttacattta tttttatgtc aagttcataa taagctggtt
    12301 catcaaaata ttcgaaacct gtagcaatca tccgataagc atttttccgt tctggaaaat
    12361 aaacttcttt ttcaatgata ttatagggac tacctttgaa gtgtattttc tttgaatcag
    12421 ctactacatg cacgattttc gatccactat aattctcagt cgttgtgttg aaaacaagga
    12481 cttcattcga ttttagcttt aatgcatcag ccatccgttt tacaataagg ttttcgattc
    12541 cgtcagctat ctcattagct tctttgattc gatggaaaat atcttccgca acattatctg
    12601 aaacacagcc accaatacta tcatgagcct ggttttgcaa aatctttttc cataaccgac
    12661 gaagtaggcc tttactgata tggataccat ttctttctgc aatcagcatg agcggctcaa
    12721 ctcgttttag aattttttgt tccaatttaa aattttctat tttcattttt gttcttactg
    12781 agccaataga acgatgaaca cgagagtaaa ccggctgacg aagttcacct ttatattcag
    12841 gtaattcttt tttgtttctg ataacttcta cataagaagg ataatctgaa ataatattgt
    12901 ggaatttact gtatttattc aacttctcta cgacttgatc aaaatttaaa atcattgact
    12961 tttgatctac acccgaaggt actaaaatat ctttgttttt tccttgcata tgaagcattt
    13021 caactgcttc atccaacttt tcttttgcaa attcaggaat atctttaatt gcgtctaagg
    13081 tcatcattcc agtcatataa ccaaatggaa aattcatggc ataaacaaat ttatctccca
    13141 atcctttcca gataaaataa ggagatggaa ccatcgtttc aaagtttaat cctcgccaac
    13201 acatgaaatt atcgatttct acttgatgca aaagtgtagg caaattcgca ttgaacccaa
    13261 acgtgtcagg caaataccct accatcattg gatctccata tttaaggatc gtatcactga
    13321 ttccaatcat taagtttctt aaaattgatt cagcatccac taataaggca tctgtttgtg
    13381 cataccacgg tcccacgaat agttgtcctg ttttcatcag tcgttggata accttaagct
    13441 tttgcggatt gatctccaaa tactcatcga cgattgaagt ttgtccatct aaacaaaagt
    13501 ttactttagg gttcctttcc aattcatcta gaacttcagt aaagacctga tcagacaata
    13561 cgatggcatc ttcatttgta aaataccatt ctctgtccca gtgcgtgtgt tgaattatat
    13621 gtgcatttac catatcagat tctcctactt tccttcttct actgaattta cttgttgttc
    13681 ttttttatac ttgatggatt ttagtgcatt gaccattaac gctgtaacca ctcccccaat
    13741 aacaattgat actaaatata aaggtatatt cgtaacaaaa ggaattgcca taaaggttga
    13801 aagcattgtt tcttgagtaa caccaaaaaa tccatttaga ccacatgcta ctgcagtgcc
    13861 caccacgatg cttggtatta ctcgtaaagg atctttcacg gcaaacggga tcgtcccttc
    13921 agtaatcccc acaaggccca taatcatagc tgtctttgca ttatctcgtt ccgattcatc
    13981 ataaagtttt ttgtttaaaa ttgttgctaa aaacattcca aatggcggaa tagcaattcc
    14041 taataacatg gctgtactag gtccaaagct tccgcttgaa aaagaagcaa ccccaaaagc
    14101 atatgcgatt ttattgatag gtcctcccat atcaaacgcc atcattcctc ctaaaatagc
    14161 cgacatcaaa gcagcatttg ctcctgacat gccttctagc caattagtca gtcctgttgt
    14221 cattgcttga ataggcgtag ctagtacata ccataatatg attccaacaa ctaatgtagt
    14281 aacaaaagga atcagcataa ttgattttag actaataact tgcatcggta cttttacttt
    14341 tttcaatgca ttagctaaat agccacaagc taatccagca accattcctc caataaatcc
    14401 cataccaaga ttttgacaca tcatcccagt gataaaagct ggtgctagac cgggacggtc
    14461 agcaattgaa tatgcgatat aggctgaaat catcggtacg ataaactgta atcccgtctg
    14521 accaatcatt cgcaggactc cccagaatgt atccgtctgg tcccaaacac ctgtgccacc
    14581 aaaaatgact gcaatagaag ttagtaaccc tgctgctacg acaagcggga tcatatagga
    14641 aaccccactt tggaaatgat ttagaatttc tcttccttgt ttcttgaatt ccattagtaa
    14701 ctcccccacg atatattttt tatttgttaa ttaatgcaat tgcttcatca atcgtctctt
    14761 caccatcttt tactacctct gaggtcccta ctgttaaaat cggtttaccg tcaaagcgac
    14821 ctcgttctga aacatttgta tctactgcaa atatgacaac atctgcctcg gaaacatccg
    14881 aaattgaaag tttgttttct atccccatag ccccctgtgt ttctacttta atatctaacc
    14941 ctttcttctt cgcaaacttt tctaaattag cttttgccat ataagtatgg gcaatccctg
    15001 cgatacatgc tgttactgct actatttttg tcatatgaaa ttcctccttt taaaatgata
    15061 gagcttttac caattctttt ttatttctcg aatcttttat tcttttaaca aactcgtcat
    15121 ccatcaatct tccagataat tctgctaaaa tacgtaaatg attagtacct ttatcagtgt
    15181 cttttattgc taacaaaaag acgagatcaa ctggttgatc atctaatgcg ccccattcaa
    15241 cagaccgctt taacttggct acagccactg ttgattcaat tactgctagg cttttgccat
    15301 gaggaatggc gatatttttc ccaattcctg tggtcatatg gttttctctg tcaaatacgt
    15361 ctttttgaaa ttgtttgtgg tcagacacaa acccattagt ctctaacaat ttcgataatt
    15421 tttcgactac acttttttta tcagatgcat ttaaatctat cactatatta tttatattga
    15481 ttttttcact gatcatttat aagccttctt tcaatatata aactaatttt tcaaacgacg
    15541 aactcgtttt taaatttgct aataactcat gattcgaagc gatttcattg aatgtttcat
    15601 aaattttatt caattcaggt tttacttttt cattaagtgc aaaaaagaaa acagaatgaa
    15661 caagtgtccc atcccaatca attccttctg gattaacgta gacacagatt actggctttt
    15721 ttataaaatc tacttcgata tgcggcatag caaaatcatt catcgctgtt gaagatagtt
    15781 tttctctttt gattgctccc tctagtatcc cttctttcgc gtaattttct tttaccaatt
    15841 ttttggtaat tatatttaaa acgttcactt gattatcctt tatttggtgg gtaaaaaagc
    15901 aaaatcgttt atctaataaa tttagaaaag catcttctgt ttgttcattt aactgtagat
    15961 actgttttac ttttctgaca tctgccccta acatcaaagg actaacaaca ataacaggaa
    16021 aatttgtatt ttcaatcgga atcgtgctta taacaagttc atcagtgact tttctatctt
    16081 gtagttcatt gatgcttagt acatcttcta tctcaaccat atctgcaaaa ccgttattta
    16141 ttctttgctc taataatttt gatgttccat atccgctact acaaactaat atcactttcg
    16201 ttttgtcagg tttgtaacga tccaaaagtg attgaatatg gagtgttacg taagcgattt
    16261 catcttcatt aaaatgtata cagaatctct cttcgatttc ctctaataaa tctacactta
    16321 tcataaatga ccttttaaaa gaatatttga ttttgtccgt ataagggtta tagatattta
    16381 ctcccaattt gagtctttta actgctgcat tgagatgtaa tactagatta ttgatcaatt
    16441 cttcatcagg ataaaattca tttaatttaa ttcttactaa ctcttgtagc tcaacaccca
    16501 tatctaaata ggaaagcttc gtttgatcta agtcgtgatt catagcattt ttttcaatcg
    16561 aagtaatgtg aatgtcaaca taagcttgtt catctattgg cacaataatt gaaaatgctt
    16621 tttcaatcat tttgattaaa ataagtgtat tctttgagat ttcttcttca gaattattac
    16681 tacgtgataa gaaattgctt gtttcaatcc tttctatcgc aatagcaagg tggatagcta
    16741 aagtttgaaa ttcataatct gtaaatttca attgtgtctt attcatgtat cgattaagca
    16801 attcggctac ttttttcaat atgtccttat ttaagaaatt attcgcttca ccaatgaaat
    16861 tgatattcaa gtctaagaga tctgttttac tgttagatgc tgtaaagcca ccccaataat
    16921 agttcacaac ttctgacatc aaccttcttt tacttttttc atcagctttg atgcgcacgc
    16981 catttcgatc tgaaactaag gacatcccat gcttgtttag tctttttcta acatctttca
    17041 ttgtgctttc taccgtcgac ctgctcacgt ataattcgtc agcaagattt tgaatcttta
    17101 gagaatcatt agtattcaat aatttagcaa acacataagt tagacggtcc tccggagagt
    17161 ctgcgatatt gattttatga ctggataata aatttcgaag tgtttctttt tttccaataa
    17221 gcgaaacgcc ttttttaggt tgaaccaaca tttgtacatc tggcattttt tggattattt
    17281 ctttcaaaat taaaatatct ttgctaattg ttttcgtaga tacatataat tgttctgata
    17341 attctttgta agttgtgtgc tcattttcaa tcaaaaagta tagtattttc atttgccgtt
    17401 cgctaaattc gatgcccatt atcttcacct cctgaataca gcttaagtgt acaattatta
    17461 tctctatttt catacagaag aaagttcttg attaatgtag aagtttctaa tattcttgat
    17521 tatttcaaat caataaaaaa gcctgcaata tttatatcac aggctttttt ctctattaaa
    17581 tatatataag ataatacatt tttctactag ttctcactaa tcttgtataa ttaaaccctc
    17641 cgcaacttga cggagatgga gaagatgccc ccgtctaatc tagcggtcat ctctcctccc
    17701 attccttcca ccaatttttt tgacaggtaa agcccgattc cgctagattc cgtatttgtg
    17761 cggctggtat tttcggtata aaaacgctgg aagacttttt caacagaggt ttgcgttcct
    17821 ggtttgatag gattggccac tgttaatcga atgaatggat cctcttttga aaatgtcacc
    17881 tttgcttgtc catctgcata acgcaataaa ttctgtatga tattttgcag cactcgcagc
    17941 aacatgagcg gatctgctaa tacagttgta tttatcgagt gttcagcgaa cgctacctcg
    18001 atatttttct cagaaaattg ttcataaaaa gagaaaaata cttcttccac ctctttagaa
    18061 aaagaaagcg tatggagatc catttctttt tgcttcgtct ctattcgagc aagatcataa
    18121 aactgatccg tcatactgag taatcttgca acagattgtt tgatgatcgt taaatacttc
    18181 tcccgtttct ccgtatcctc tacctgttcc agtaattgta cataaccgtt aatagcagtc
    18241 aaaggagttc tgagatcatg agaaaggccg acgatcgata gtctgatgtt ttcttccatt
    18301 tcttgaaatg cttgtccttt ttgttcattt tcatccaacc atgtattcag tgcatctact
    18361 aggtccatta gattcttttc tcgaaattcg actgaaagac gaccaccata ttcttgtcgt
    18421 tcagaaagag tggcgatttt cttagttaat ctcttgattt ccctttgcag gaagaaaata
    18481 aaacttccca taaagataac aacgagaagc aacagccatt taatcaaatc taaaccccac
    18541 tccccacacc gtatgaatat acacagcatg tgcctttgct agcttccctc gaagattgga
    18601 aatatgcata ttcactgttt tctcactatc aaaatatggt tcttgccaaa ctgtttcata
    18661 aagatttgct cgcgaaaata cttttttcgg atgttctaaa aaaagcttca gcagatcgaa
    18721 ttctcttcct gtcaaatgga cagccacacc attcacattt acatccctcg actctttgtc
    18781 cagtaagatt tccttgtaat agatgcgttg cgacagatct tttacttgga cagaagtctg
    18841 atgacgaagt tggatgccga ttcgtaacaa aagttcttcg atatcaaatg gtttcgtcac
    18901 atagtcatcc gctcctgctg ccaacaagga aactttatct ctttgatcgc tttttgctga
    18961 aagaacgatg atcggaacat tcgatgtctg tcggatttct gctaacaatg cttcacctga
    19021 aagccctgga agcatgagat ctagaaggat caaatcgaca ggatatgtgc ttaacaataa
    19081 ttttccttcc gtacctgaat aagcatcaag aagtttgtat ctctgttcaa gaacctcctc
    19141 cagtaaggaa tgaacagctt catcgtcttc gataatcaaa atagtttcca gcaggaccac
    19201 ctacttaatg tcagattttt ggaaaataaa cattcctaga gctgatgata ccacgattgt
    19261 tactagactg accagaatca ttttcggtgc ttgcgaataa gttgcttgtt gcgcaaagtc
    19321 cgtatacatg agccacgttt ccgtaaacca ctccgttaga aattccaagc ctttgatttt
    19381 tgcgaaaaca ccgggaatga aggccgttcc catgatataa agaaaagaaa gaagcaaact
    19441 gacactggta cttctagtga tgaatgtcaa agccactgga acagataatg tccctaatgt
    19501 cagcagaagc aatacaggaa atacttttag aacataattt ccatagtttt tgattccctc
    19561 aacttcacca aatccgaaag caagtgtgta agcaagcatg gctagtcccg tgatcaaaac
    19621 cacgccaagt gttgtgatca aaagcgtaac gagaagtttc gacacataat aagtcattcg
    19681 attccgtcct aaagataacg tattgcgaat cgtaccgttt tgaaattctt ccccaatata
    19741 aaagcacgca aatgctgcga aagccagaag aatccatgca gccatttttt ctaccattaa
    19801 aatccctgtt gcaccgttga tgactgtatc cgttgcttgg tttaattcat tgccgtattt
    19861 tgtatgcata taccattcgt tccaagaata aaaaagcgga agtacgacca tcagtcctag
    19921 tgagacccac attttacggc tcttccatac ttttattttt tcagcagtta atagattaaa
    19981 catgtggatt gcctccagtt aattgtaaga aataatcttc cagtttttgc ccaactaggt
    20041 gaataccatc cacaggaact tttgcttcta ccaatgcttg attgatggct gctacttggt
    20101 caattccttc aaaaagctgg ataacacggc tagattgtac aaaataatcc ctataaccaa
    20161 gagagtcgag aaccgttact gcttgttccg tcgccgaagt gtcaattttt ataaattgac
    20221 gagattcttg tgccaattct tctttcgata attctttgat caagtgtcct tcatgcaaaa
    20281 taccatagtg agtggcgatc tgtgacaatt catctagcaa gtggctagaa agcaagacgg
    20341 tgatgccccg ttcttttacc aaacgttgga tgatttctcg catttctgcc atccctgctg
    20401 gatccatccc attcgtcggt tcatccaaaa tcaaaaattc tggattcgtg atcagtgcat
    20461 ttgcaatagc taaacgctgg cgcataccta aagagaaatt ctttgctttc tttttccctg
    20521 tattttccaa tcgcatcatt ttcagcaggt cttcgatttc tctatccgac acaccgccgt
    20581 tcgctgcttg gatacgtagg ttatctcttg cagttaattc tggataaaga gcaggggttt
    20641 caatcgattg acccatacgt cgtcttgctg cctgcaaatc cgtcgttcca aataattcga
    20701 tcgaaccttc atcaatcgag atcaaaccca taatagttct cataaaggta gacttacccg
    20761 ctccattttc cccaatcaat ccatagatca ttccacgttt gatttcgatt gatactttat
    20821 ctaatgcttt ggcagcaccg tattttttgg ttataccagt tgctttcaag accgtttcat
    20881 ttccaaaatc catacttatc cttctttctt attgatgagt gaagtatagt tgacgggtat
    20941 aaagaaagca gccagaaatg tataaagaaa gtgtaaattt tccaattgaa tgtcaaaaaa
    21001 aacaatcgga caatacgtgt ctttcctatt atcaggcagt ttgttatacg cttgtatcag
    21061 tttcctgatt ctttcttttc gaccaaagtc gtttctctgt attcctcttc actgaaaatt
    21121 tttgcttctt tcagatcaag cttgagtaat tttaccagac cggttataag gataactata
    21181 gcaagactcc ctcccagaaa aattagactg tctcgcagac gtggttgcgt tgtcttccaa
    21241 tcaaagagcg caccaaacag tgctaatcca agtggactgg ccaccatggt aatcgttgtt
    21301 atcgttgaca taagtcgtcc ttgtatatgc gttggaactt ctcgctgaag ccagaccata
    21361 taaaaagcaa aagaaaacat taatccttaa aaacggactt atgaaaaata atacatgccg
    21421 tttgggattt acaattagct accaaataag aggttatgac aaaagacttt tcacaatccc
    21481 ttcttccgaa taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatttatc
    21541 aaacatgaga agcaattttt gtaaattcct tcttatttct tgaagctgac cacttctgtc
    21601 acaacctcag aagcggataa ataatattgt ttgatgatac tttatctttt tcccgtttgt
    21661 ttatagatcg aatgatatta tagaccaaga atcctaccta ttaacatagc taaaaacaca
    21721 aaaaaggcac tttccaaatt gtggaaagtg ccagaaaagt taggattaag gtaactgcgc
    21781 tcagcattgc ttcgcccagt acgattctcg taactcgtga actcgaacga taatcgcaat
    21841 taacgttttg agaactgtga agctttacgg gctttcttaa gacctggttt tttcttcgta
    21901 tcattgaata agtttgaaaa accttgattt ataaaggttt tcccgtaaat atattttatt
    21961 atatttgatt aaatttgaaa tgtttgtgtt ctaa
//
LOCUS       DAZKCH010000047        21798 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000047 DAZKCH010000000
VERSION     DAZKCH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.047"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            98..1438
                     /locus_tag="ACG84X_001755"
     CDS             98..1438
                     /locus_tag="ACG84X_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9127622.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1656..2099
                     /locus_tag="ACG84X_001756"
     CDS             1656..2099
                     /locus_tag="ACG84X_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFP9127623.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(2603..4021)
                     /gene="nhaC"
                     /locus_tag="ACG84X_001757"
     CDS             complement(2603..4021)
                     /gene="nhaC"
                     /locus_tag="ACG84X_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFP9127624.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(4424..5647)
                     /locus_tag="ACG84X_001758"
     CDS             complement(4424..5647)
                     /locus_tag="ACG84X_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFP9127625.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(5678..6517)
                     /locus_tag="ACG84X_001759"
     CDS             complement(5678..6517)
                     /locus_tag="ACG84X_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFP9127626.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(6534..7214)
                     /locus_tag="ACG84X_001760"
     CDS             complement(6534..7214)
                     /locus_tag="ACG84X_001760"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFP9127627.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(7216..8289)
                     /locus_tag="ACG84X_001761"
     CDS             complement(7216..8289)
                     /locus_tag="ACG84X_001761"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFP9127628.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(8345..8583)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(8626..8859)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8936..9607)
                     /locus_tag="ACG84X_001762"
     CDS             complement(8936..9607)
                     /locus_tag="ACG84X_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9127629.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(9694..12342)
                     /gene="mgtA"
                     /locus_tag="ACG84X_001763"
     CDS             complement(9694..12342)
                     /gene="mgtA"
                     /locus_tag="ACG84X_001763"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFP9127630.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(12684..12858)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            13031..13468
                     /gene="ndk"
                     /locus_tag="ACG84X_001764"
     CDS             13031..13468
                     /gene="ndk"
                     /locus_tag="ACG84X_001764"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFP9127631.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(13490..14356)
                     /locus_tag="ACG84X_001765"
     CDS             complement(13490..14356)
                     /locus_tag="ACG84X_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFP9127632.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(14516..16609)
                     /locus_tag="ACG84X_001766"
     CDS             complement(14516..16609)
                     /locus_tag="ACG84X_001766"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFP9127633.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(17358..17981)
                     /locus_tag="ACG84X_001767"
     CDS             complement(17358..17981)
                     /locus_tag="ACG84X_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127634.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(18140..19537)
                     /locus_tag="ACG84X_001768"
     CDS             complement(18140..19537)
                     /locus_tag="ACG84X_001768"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9127635.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(19569..20540)
                     /locus_tag="ACG84X_001769"
     CDS             complement(19569..20540)
                     /locus_tag="ACG84X_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9127636.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            20914..21339
                     /locus_tag="ACG84X_001770"
     CDS             20914..21339
                     /locus_tag="ACG84X_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127637.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT         6286 a         4500 c         3778 g         7234 t
ORIGIN      
        1 aattgtctga aaatttgtta tcattagtca ttgttaaata ttgctattta ttcttaatat
       61 aaattttgat tgtgaattta aaagaaagag gtcatttatg gaagataaaa aattgaaaaa
      121 acaacttagc tccagacata tcaccatgtt agctttaggt ggagcaatcg gtgcaggtct
      181 atttaaagga agtggcgaag cgattgggat cgccggccct tctgtattga ttgctttttt
      241 gattggtggg ctgattttat atatcgtgat gaaaggtctg ggaaaaatcg ttttaagcgg
      301 tggcgacacg catcacggat tatctggttt gatacgccct tatctaggtg ctcattctgc
      361 tgattttact gattgggtct actggtctat gtggattatc aatatcatcg ctgaagctgt
      421 tgcagctgct tcctttttgc agttgtggtt cccgcacatt ccagcctggg tatttgtttt
      481 tatgttggct gttttaacta cgatcatcaa tctttattcg gtacggttat tcgcagaaac
      541 agaatattgg ctggcttttg ctaaaatcag tgtcattatc ttactgatca tttttgctac
      601 ttatcttgtc ggtcagcaaa tgttgggcac aggcgttttc cctacccttc agcaattgac
      661 tgaccatggt gggtttactc ctcatggtat gaagggaatc atcagttctt tgcttgtagt
      721 tatctattct tacggcggtt ctgaactgat tgctatcacg gtaagcgaag cagatgatcc
      781 taaacgtgcg attcctaaag caatcaaagg tgtcatggga agaatcattt ccttttacat
      841 cattcctttg tttttgcttt tgattctttt tccttggaat actttagcag gcacgaatgt
      901 cagtcctttt gtgatggtat ttgaaaaaat gaatatccca tttgcagcgg atatcgtcaa
      961 ttttgtgatt gtccttgctt tgttctcatc tatcaattcg ggtgtgtatg catcttcaag
     1021 aattttgttc ttccgtttga aggatcgaaa aggttcctct agaaaactag ctgttttaaa
     1081 caagcatcaa gtaccgcaac gtgctgtttt attttgtacc agtgttcttt atcttggtgt
     1141 agctctttct tattttgtcg gtgacaaatt atttggctat ctggcaggtt ccctttcgta
     1201 tacagtatta ttgatctgga tcattatcag tgcggcatcc tttgtactgg cactaagaaa
     1261 aggaacatta tgggataaag gaatcagctt ttttgcatta gctgtcttag gattgatttt
     1321 ccttggtatc ctgttcacga actccattgg ggtaactgta ttgactggcc tgctttacct
     1381 gttcatttat ttcagttatc aaaaaaagaa tgatgcgttc gtattgacga atgaatgaaa
     1441 tcgatagaaa attttatttt atttatgtgg aatagatgga gctattgaag aaaggagttg
     1501 tgacaaaagt cttgttgcaa ctcctttttc cgaataaaca gtctcatgac ctcttggtaa
     1561 acggtgttca aaaaccctct gtgcaaaata attgattgtt ctccatgctc atgacatgat
     1621 agaagaaagg aatgaaaaaa aggagtttgt tttaaatgaa aaagtattgg aagtttttgt
     1681 tgatgatcgg tgtttcaacg gtagttatgt ttggtatgat gtacttgaat gtctatgcgc
     1741 tcgatcatat cttcttcagt cgtacacgag tattcatggc gttgatgatg ggtgcagtca
     1801 tggcagtcat catgctgttg ttcatgtgga aaatgtatga aaacaaaaag ataaatgtta
     1861 tgatcttagc cgctagtctt cttgtttttg ccggttcctt gtttatggta cgaagccaaa
     1921 ctactgtcaa cgacacagct tggatgaagg ccatgattcc tcatcattct atcgctatcc
     1981 tggcaagtaa acgagctgat ttaaaagatc ctgaagtaaa aaaattagcg gaagaaatca
     2041 ttcaggcaca agaagaagag atcgacaaaa tgaaaaaaat gatcaaagaa atggaatgac
     2101 cattatccgt ccaaataaaa aaagaggatg ttccagaagt tatcagcttc aagaaataag
     2161 aagaagctac ttctggaacg ccgtgaataa ggggttgtga aaaagctgcc ctgcatcaag
     2221 taataagaac agccaaacaa aaatagcttc tcctattttt cgtttggtta ggcttattac
     2281 cgcagatgca agcttttgaa caccgtttat taagaggttg taaaatcagc gttctgacct
     2341 gagtattaga gagacaaatg gaaaaatagt tcctcatatt ttgccatttt ttgagctaat
     2401 accgagggtc agctgattga acaccgttta tcgagaggtt gtgaaaaagt cgcttagttt
     2461 cgcgtattaa gaaaaatttt gtgaaatggc tttccacatt tttgtataaa tttggcttaa
     2521 taccgagaaa ctggcttttg aataccgttt attcgtaaaa gggattgtga caaaagtctt
     2581 gtcacaatcc ctttttatgt ttttattgtt ctaattgcgc tgtcttgctt actgcttctt
     2641 gcggtttcac aaattttttt gagattcccc aacctgtgaa ggcactgacc atcgaaaaca
     2701 caggagaaag caaactgaaa aatacgaatg gcaagtaagt gagtgtagga ataccaaatg
     2761 tacttgctac gaaacttccg gcaattcccc aaggcactaa gtagttgatt actgttccac
     2821 catcttctag cgttctacct aatacagttg gatcaaatcc tgctttttca taagtttctt
     2881 taaatgcatt accaggcaga ataacagata ggaattgttc accaataaaa atatttactc
     2941 cgatacttgt catcaatgtt gtaaaaatca aatttggtgt gttcgtcatc tttcttgata
     3001 ctcgttccat cacggttgag atcaagccaa attcgatcaa caatccacct aatgacaaag
     3061 ttagaataat caatgacaca gtaggcatca tactttcgat tcctccgcgg ctaagcagtg
     3121 aatcgatttg ttggtttcca gtatttgaaa caaaccctga ttcgatgacc ccagccaact
     3181 tcgttaagga agtttgtggg ttttgaataa aaatcattcc tactgctaca gcgatattca
     3241 acaaaatcgt taaaattgcc ggcacctttt tccatgcaca cagtaacatt aaaaataaag
     3301 gaatcagtga ccagattgaa atagtaaagt ttgcttctag aacatcagtc acttcacgaa
     3361 tagatgaaag acttgcggct ttacttgtgt gtcctaaaat catgaataaa aagaaagaaa
     3421 caacaaatgc cgggacagtt gaccacatca tatgcttgat gtgtttgaac aaatcggcat
     3481 caacaatagc tgctgctaga tttgttgatt cggataatgg agacatctta tctccaaaaa
     3541 cggcacctga aacaatagct ccaacaacca gcgctggatt taagcctagt gttgtcccaa
     3601 taccgaaaaa tgcaatccca atcgttgaca taacagtaaa ggcactccct acagcgctac
     3661 ctacgattgc acacacaaca aatacagaag ggacaaacca ctggacactg atcaatttga
     3721 acccaatgac cattagagtt ggaatgatcc ctgcttgtat ccatacagca atcaatgaac
     3781 cgactaaaat aaaaataaag attgggatga ttcctggttt gatgccattg atgattcctt
     3841 cgtgcagcca atctgtcggg tatcttttta tcactgcata caacatgacc attccgatcg
     3901 ctgctaagat cgtgatatta ggtgagacct ttaatccgac aacgccaatc gcaatgccta
     3961 aaacaataac cattaataca agtgttgctt ctaaaaaact tggtgttcct ttttttccca
     4021 tgataatctc tcctttttta gttgttctta tgttctaaaa aagttaagat atcggattac
     4081 tccgccgcaa ttcatccgcg attcctcctt tataaaaata aaaagacctg ttttaaacta
     4141 aggacgaatg actccgcggt accaccttaa ttaaaaacag atctgttttt cactttcaaa
     4201 cttttattca aatgtatgga ctttccatgt aattcgtcaa ttaggcttga tcggttcaca
     4261 gcgaccaccg actttctgaa caaaacacct aaccgctact gcgtgaaaag ttgacttgta
     4321 cgaagtttac cttccataag atcatttgtc aatgaaaaag aaaatatttt ttcatttttc
     4381 tgaaaattat ttttataact ttcacacaca agattatttt ttactagaaa gtagcgccct
     4441 cttgtttttt tcttgctact atttcttgat gttcttgctt gattctttct aatagctttg
     4501 gctctttcaa cagatcaaga gctgtattgg cgagtagttc tgctgcaatc gcaatagaag
     4561 caaggccttt gtcactttta gcagcagctt tgaattcttc tgtgtgtccg gcaatatatg
     4621 tctcagagat tgctaccgta ggctggattg ttggtatgac ttggctgaca tttcctacat
     4681 cagaagaacc gagacttgtt ctttgttccg tttctatttc ttcatctgga acacctgctt
     4741 cttttgcatg ctggaagaat aagtcatcaa aagaaggagt aacgatgaca tcatcaactg
     4801 cattttggaa caatccaaac tcaaaagtcg tgcccgtact tatcgcagca cctcgtacga
     4861 tattttccac tttttcatat actttatcta atgtttgccg atttcctgca cgtaaataga
     4921 aacgtccagc agcgtaatct ggaatgacgt tggcagctac tcctccgtct gtaatgatcc
     4981 catggatatt gacatctttt ggcaattgca agcgtagagc gttgattcca ttaaacactt
     5041 ggatcaatgc ttccaaagca tttactcctt tttcaggtgc tgctgctgca tgggaagcga
     5101 caccgtaaaa tttgatgtcg actggatcat tcgctaaaga ttctgtcgtt ttcccataac
     5161 gaaaagctgg atggacgcat aacgctacat cgacatcctc aaaaaaacct tctcgaacaa
     5221 agctgccttt agctgatccg ttctcgcccc cttcttcccc tggggtgcca tatacacgga
     5281 tttctccacc agtttcatca atgaattgct tcactatgct ggcggctaat acggagtaag
     5341 taccaaacaa attatgcccg catgcatgac caatacctgg taaagcatcg aattctgcca
     5401 aaaaggcaat tgtgggaccg ggtttattgg aaatataacg tgcatcaaag gctgttcggt
     5461 gtccagctac ttctttttct acccaaaacc tttctttttc taattgttta atcaacgctg
     5521 ctgaggaata aaactcatag ttacttactt caggatgttc gtggatatct agagcaagtg
     5581 cttgatattc tggtaaacga tattggatta gatccttcaa ttggtttgtt gagattgttg
     5641 ttgtcataaa aaattcctcc tatgctagtc atttttctta ttttctcccg aatgtttccc
     5701 atgcaggcac gcttgatcct tttgatgttt tctcgattac tttgactgtg tcttctgttt
     5761 gataagcgtc tactattttt tgatacgttt tattgttttc atcttctttt cttgcaacga
     5821 tgatattcac ataaggacgt gcatggtcat ccactggttc taagaagatg gcatcagaag
     5881 caggattaaa tccagcatct acagctacac cgctattgat cactgaaatg tctacatctg
     5941 acaaagcacg tgctgtttgg gaagcatcta attcagaaat gtctagattt tttctattct
     6001 cggtaatatc agaaacagtg ggcgcttgtc cttttgcctt atccactttg atcaatccag
     6061 cagtttgcaa taacagaaga gctctgccgc catttgtaac atcattaggg attgctactt
     6121 ttgctccgtc tttgatatca gctacatcct tcaaagtgtt agaataaatt cccagcggtg
     6181 cattgacagt atttccgatc gatactaaat cagttccgtg ttctttattg taattgtcta
     6241 aaaagaattg atgttggaaa gaattcaaat caatcgatcc atctgctaaa gccacatttg
     6301 gttgattgta atctgtaaat ttcacgtatt ccaaattaat gttctccttt ttcaaacggt
     6361 ctttcacgtt gtcccataca tctgtatctt ctccaataat ccctagtttt acgatagttt
     6421 cttttttgtc agttgtatct gcttttcctt ggctacaccc tgccaaccaa ataattgcta
     6481 caaatgtaat gactacaaaa cgaataattt ttttcatttt ttctcctcca ctttcaatgt
     6541 gtaatttttt taatcagttg attactgata aattgactta aaaaaactaa gattagaatc
     6601 aataatgtag ccacaatcgt tacatctgtt tggaatcgat tataccctct cgatatagca
     6661 agattcccta atccgcctgc acctactgct ccagccatgg tagtcagtcc gatcacgttg
     6721 atgatagtca acgccgagac ccgaatgata ccaggcaaac cttctaacaa atacacacgt
     6781 aaaatgatac cgattggact ggttcccatc gcttctgccg cttcgatcac cccaggatca
     6841 acttctagca gtgcgttctc gatttgacga gcaaaaaacg gaacaactcc aaaaatcaat
     6901 ggcactaaag ctgctttcgc accaatcgtc gttccaacta agaaacgagt agtcaatgct
     6961 aaaagagaaa gcaagataat gaaagggatg gaacgaatga tattgatcag cttatcaagt
     7021 atttcaaata gcagacggtt agctagtaat ccattagggc gtgtcactac taacgtcaca
     7081 cctaagatga ttccaatcat cccgccaatg aatgctgtcc aaaaagacat atatagtgtt
     7141 tgcttcgtcg cttcgacaaa ttcatccgga atcaaataaa cattgggcaa atatgtttta
     7201 aagaaatcag tcattttatc ttcctccttc gatcactttg atacgactat ctaaatcgtt
     7261 tttttgtaaa atatttattt ttacaccaga tttgatcaaa taatccaatg cttttttccg
     7321 ctgtttggtt tctccagcta aagtaacgat caaactccct aacggcgttt cttgtaataa
     7381 ctctacattg ccatataaaa tattcgctgt tacttgatat ttgctgtaca gatgagcgat
     7441 tagaggttcg ttcgtctgat ttccaatata acttaattcc accagccatt tattggcgat
     7501 ctgatcggca aaagcagaat gggcaatgat cgtttctaat gcttggtcaa gatgagtagc
     7561 tgttcgaata aaatctttgg tcaattcttc ttcaggattg ctgaagatct ggatgctgct
     7621 acctttttca acgattcttc catcttccat aaccgctacc ttgttgcaga tttctttgac
     7681 aacttgcatc tcatgagtga tcaggacgat tgttaaacct aactggcgat tcaatttttt
     7741 taacaatgca aggatctgaa gggtcgtttt cggatcaagt gcactggttg cttcatcaca
     7801 taataatacc ttaggttcat tcgccaaagc tcgtgcgatt gctactcgtt gtttttgtcc
     7861 ccccgacagt tgtttaggat aagcagatgc tttttcttcc aaaccgacaa gttccagtag
     7921 ttcattcact ttttgacgac gttcctgttt cgattttcca gaatacttta aagaaaaatc
     7981 aacgttgtca aaaatagttc ggctttccat tagattgaaa tgctgaaaga tcataccgat
     8041 ggcctttctt tcttttcgca attctttggg agagagctga ctcagattcg tctgattgac
     8101 aatgacttct cctgctgttg gtttctgcag caaattcatc acacgaacta acgtactttt
     8161 ccctgcacct gagtaaccga cgattccata aacatcgcct ttttcaatcg ttaaatctac
     8221 agaatctact gcctgtatct ctttttcttt ttgtttgaaa catacagaaa catctcgcaa
     8281 ttcaatcatt aaaattcctc cttatctaaa aaaagcgtcc tcaagaaaat gaaaatgtca
     8341 ttttcttgag gacgcttttt tgcgtgttac cacctcatgt tcaagctgtg ttcacacaca
     8401 actcctcttc aagtacgatc atactctagc aagatatcgg tcgcagccgt catcgcctta
     8461 catctatgct cgggatgaat tgctcgatgg ccattttcca atagtcgttc cttgcttctt
     8521 ctcagctacc gaagctctct gtcaaaggtt cttctatcgt acttaccatt tcaatgcaaa
     8581 taatattcaa aaaaaaagtc cttttactaa cataaactat gtcagtaaaa ggacgacgta
     8641 tcgcggtacc accttttttc ggaagtttcc ttccctcaag cccaacatct caaaaagaga
     8701 gattggcgtt cgttttaacg gtcgaacagt tccgaatttg cctacttatc gacaaattat
     8761 tctccaaggc cattttcagc ttttcttact tgactcttct caccagccag agcctctctg
     8821 caaagtttcc aaacttactt tccttttcaa cgaaatcgat attttgttgt tgggattaat
     8881 ctacatgagg aaaactgaaa agtcaagtac gaaattcaaa ttattttttc tatatttatt
     8941 tttctgtttt tttatttaac atttcaataa cagttcgaag atcttttcct tccgcaagaa
     9001 gtttcaattt ttccttttct tcgacggtat aatttcggac aaaactggaa tcaggtatca
     9061 aaacaacgcc taatcctgct cgtgaagcag ctgttgctcc tactaaagaa tcttccactg
     9121 caaaggctga actagcttct aatcctgttc gttccaaagc tgtcagataa ggaatcggtg
     9181 aaggcttgtt ctccgacact tcgtctccga atgtaaacgt gtccaagtaa tcagctaatt
     9241 taaagtgatc caagatatct gttgctcttt tcgtaacagt ggtcgtagca atgcctagtt
     9301 tcatatgacg ttcttttaag tctgccaata tttcttttgc atatggtttt aagtggatgg
     9361 ctccgcttgt cagctgttga taaaaatatt cttcacgctt cgctcggact tcctgtactt
     9421 tttcagggct acctgctgct ttcactaaaa tatcaaaact ttgtttccag ttttttccgc
     9481 cccaagcgtc aacgatttct tttgggatat ggatatcaaa ttgctgaaat ccccaaagcc
     9541 agccatcacg atacgttttt tctgtgtcaa ctaacaaacc atctaaatca aatattgcac
     9601 ctttcatcta tacattaatc ctttccaaaa caatacacat agtttagcac gactggtcca
     9661 aaaagaacag aagcaaagaa ccagccttct cgtttataag agttcttgga atcgacggat
     9721 atagattttc ttcacagctg tcacaagcgc cagataagcg atgactgtag caaataacca
     9781 taaccagtaa ttgccaggaa gtggcatcaa gcctaattca gcaccaaaac ttgtaaaagg
     9841 aaggacagaa ccgacaataa ttcctaatgt agtgataaca aacatggcaa atgttgcgtt
     9901 gctttggata aatggtactt tcggtgtacg cagtgcatgg agcactaagg tttgtgtcca
     9961 tagtgattcg acaaaccatc ctgcatggaa taatgcgatg aaaatcactc gctgtgaact
    10021 atccaatgta tggaaacttc cgcccactac agcaggacaa ataacaaaat acatcaacaa
    10081 gtaagtagta atatcaaata tcgaacttgt tggaccaaag taaaccatga attccccaat
    10141 actagatgca ttccattttt ttggctcgtc caaatattct ttatccatcc gatcccatgg
    10201 caaggaaatg caggaaacat catagatcag attcaaaaac aaaagttgta aaggcagcat
    10261 tggtaaaaat ggcaggaacg tacttgcaat cagcacggaa aacatattgc caaaattaga
    10321 acttgctgta gccttgatat atttcatgat attcccaaaa gtttctcgtc cagaaagaag
    10381 gcctctttcc aaaatcgtca aatctttttc taaaaggatc acgtctgcag attctttcgc
    10441 aatatccaca gctgtatcta cagaaatacc gatatcagcc actttcattg caggagcgtc
    10501 attgatacca tctcctaaaa atccgacagt atgaccattt ttacgtaaag ctgtcgtcaa
    10561 acgtgctttt tgctgaggat tcaattttac gaatacttca tggtcttcag ctacttgtgc
    10621 taattcatga tcactcattt ccgagatttt ctcaccggta accaattcat tgatctctag
    10681 acctacttga cggcacactg aacgtgtaac taattcgttg tccccagtca gaacttttac
    10741 agctacacca tgttctttca gagctttcaa cgcttgtttc gttgtttctt ttggtggatc
    10801 aaggaaagca agataaccaa tcaaaaccat gtctgactca tctttgactg aaaattctcc
    10861 aacgacgctt ggattggtct tttgtgcgac accaatcact cgtaagccat cttcattaag
    10921 tgactgtact tttgcaagta cggcttcttt tcgttctttt gttaatggtg taacagtacc
    10981 gccaagatca ataaatttag aaatgttcag catttcttca atcgcacctt ttgtgatcat
    11041 ttgtgtttta ccagctggat cagcaaccac aacactcata cgacgacgtt caaaatcaaa
    11101 aggaatttca tccacttttt gataattgat cttatctgta tctaaagttt ctgttgcttc
    11161 atcaatgata gccacatcta acaaattttt cagccctgtt tgatagtagc tatttagata
    11221 cgcatggcgc aaaacacgat catcttcatt tccttcacaa tccatatgat attcaagaat
    11281 gattttatct tgtgtcaatg tccccgtttt atccgtacat aacacatcga ttgcaccaaa
    11341 gttctggatg gcattcaaat ttttgatcac tgttcctttt ttggccatca cacttgctcc
    11401 tttgaccaaa ttcgtcgtaa cgatcattgg aagcatttca ggtgttagac caactgctac
    11461 agatagtcca aaaagaaaag cttctagcca atcccctttt gtaagcccat tgatgacgat
    11521 aactgctgga gccatcaatg acataaattt gatcagtagc atggatgttt tatggatgcc
    11581 taattcaaag cttgattgaa ttggtttttc agatagcgtt tctgctacat gaccaaatag
    11641 tgtttcattt ccaacagaaa caatgattcc ttccgcactt ccactgatga cattacttcc
    11701 cataaagaca agattttcgt aacttgtttc gctttgctga tcgtcttcac atactttcgc
    11761 atgcttttct actggatagc tttcccctgt caatgctgct tgggaaatga ataaatcctt
    11821 tgcggacaat aaacgcatat ccgctggtat catatcccct gctgaaagcc gaacaagatc
    11881 tccacagacg atttcttcca taggaatctc tgtgtacttt ccattacgtt ttacagctgc
    11941 cgttactttc acaagtgatt tcagtttttc agccgcttga ttggaacgta cggactgaat
    12001 caacgtcatt gtcccgctga cgataaccat agtgaagata atggctacac cgaaaagatc
    12061 tttatctcca ggagctgcta atacatattc cgtgatgaat gaaataattc ctaatgcgat
    12121 caacactaat gtaaatggcg tgatgtatgc tttcaatatt tctacaatga atggtgtttt
    12181 tttgccatat gaaatcgcat tttcaccgta attttctctt gaacgttcga tttgttcttc
    12241 tgtcaatcca tttgctgatg catggaatag ttcaaataat tcttgtttcg tttttccagc
    12301 aaaagctgca tagatttttt gtgtatcttt ctttttttcc atctcaatct ctcctttgtg
    12361 tccaaaagac agctgttctc gctgcttttg gtctttagct attcatcgga tcgatagaga
    12421 aaaaactgaa aggggctgag aacagataga taatagccct ggcctttcct ctagatcctt
    12481 gtttttcgaa tgactgtcat ccatttgttc tcatctcctt tactaagtaa ttttaattca
    12541 tgacttccaa tcatttttcg aatagttatt tttccaatta gaccacctcc tttttatttt
    12601 tcaccgatgg ggatttgcgg caacaaaaaa acctctcgcc aaatactcag cgaaaggttt
    12661 gaaaaagcat attaaaaaaa gcttctcaga tctcatcgtt gagttttgac actgtacaac
    12721 gtaaaaagca gatacctgct tttagctacc ttatgaaaag ccttatctcg acaattcctg
    12781 ttctacccat tggcgtctct cgacgttttt gggcagtagc ctatgtttgt ataggagcct
    12841 cacctaacaa atcttattcg gttttccttc gttaatataa caactaaaaa agaggatgtc
    12901 aaatcaattt tccatgtttt tcatactttt tttaaaatac acacgttata ttcctgtctc
    12961 acgcggtttt atttgtctca ttttccacct cccgctataa tagaaatata gtaggaaacg
    13021 aggtgctgtt atggaaagaa cacttgttat tatcaagcca gacggcgtga gacgccattt
    13081 agtcggaagc atcatccaac gttttgaagc aaagggactg gccattgctg aaatgaagtt
    13141 tgaaactatg actcctgaat tagcaaaaga acattatcag cacttgactg agcgcagttt
    13201 ttttgatgaa ctgatcgatt acatgacttc cggtcctgtc gtttatcttg tgctggtcgg
    13261 cgaggaagtg atcgatatcg tccgtaagat ggttggagca acaaaagctg ccgatgctgt
    13321 tccaggtacg atccgaggag actacgcgct gccggggact gaaaacatca ttcacgcttc
    13381 tgattcccgt gatgctgcgg taaaagagat cgcccgcttt ttcccgccat tcgatataaa
    13441 caaaccgtct gaaaaagcgg cgaagtgata caaattctaa actgctggtc tagttgctgg
    13501 gttcagcaat ggccagcagt tttttctcta aggacctccg ttgattcttt cctaacatat
    13561 attcgagcac tgtgaagaat tcttggtagt ctttcgtctt ttcttcccct aaagcagcag
    13621 aaatcaatct ttgataataa tctgccatca atgtttcata gatcactgta cttctttctt
    13681 tatgtgctaa gctccgtttc atatcttcat tcacactacg tgcctttttc aaccgaccat
    13741 tttctatata aaacgaagtc aggttcatta aaaaagtaaa gagatactgc tcatgattgt
    13801 tcaactgtgc taatcgtcgc attctttttt tgattttcaa ataattgttc tcaatgaacc
    13861 gatcactgaa tatccaagga aaatcagcta gaatagatag ttcaaattga ccatagtctg
    13921 gtatctgcat caagtattct tcaatgattc ggcattcata acgtaaaaat tcaaattctg
    13981 tctcagatac ttctgttttt tcgaccatgt gaagattcaa aaccaaataa tacagatctt
    14041 ctgttttctt aaaatgccta cggttattgc tgatctcttt ataaggatca aagctgtctt
    14101 cttgtacccg atctagcatt cgtctttttt tctttaactt tattggttca tccagctggt
    14161 ttcgcatcca ttcatattct gcaagtgtca tgttcattcg ctctaaaaat gatctcaatg
    14221 ttacaaatga catttttttc actgaatttg tctcaatccc gactagagaa gtcttaaaac
    14281 agattccttc cgctaattgg gactgtgtca acttcttgtt gactcgaagt ttcttgatca
    14341 attcaccatc atacataata gttctccttt ttaatttaaa tttttccaca ttcaataaat
    14401 agatacgtta aaaaggaaaa atacacgaaa aaaataaaaa aatgtttttt tcataaaaaa
    14461 taccaacctt caagcattag aatgttgtct aactactgaa ggttggtttg attgtttatt
    14521 gattattttt ttgctgttca acgtctgttc ttgttactgg atataagttg gttgttgttt
    14581 tattaccatt ttttgaaaag acacttgtcg aatgttcgcc tttttgcttt tcgattgctt
    14641 cattacgttc cgcttcattt ttatagtcat attttttcgg atcaatcgtc tcaaatccgt
    14701 ttggcacata aaaccgcaag agattttcct gattcagctt atctgaaaga cttaacgcag
    14761 tcttgacttt ttcctgatct ttggagattt cctcatcgat tcctgctgct ttcgtatcga
    14821 tgatttctcc tgtctgatta ttgtaagctt ttcctcctag gacggtgtat ttgggtgtca
    14881 caaagttccc atttcgaaaa gcaactactt gatcatgctg agaagataat aagtctgtac
    14941 caaaatgaag ataatcttta tcatcgattc ccaatagatg tagtaatgtc ggcaaaacat
    15001 cgatttctcc accgtattca tgattgactg tccctttagt ataaccaggc atatggatca
    15061 tcaatggcac tcgttgcatc tgtgcgttgt caaattcatc ccatgtatct ggatctttac
    15121 caagagcgct tgctaaatct ttattatctg tattcgagat cccaaaatga tccccgtaaa
    15181 tcacaaagat tgaattttgg taaataccag attttttcaa atacgtaaaa aattgttcca
    15241 atgattgatc cagataatgt gccgttcgaa cataattatc tactgtgcta ttgccagtat
    15301 tcaaagatgg aaagtcgaaa ttcttgtcat ccgtataata aggcgtgtgg ttggttacgg
    15361 aaagaaattt cgtgtaaaac ggctgttgta gatgctcaag atattgggca gattctctga
    15421 ataaatcttt atctaatatc ccataaccta acgtttcgtc ggattcatca aaataagatc
    15481 gatcaaagaa attgtcataa cctaagtttt tatatacatg atctctattc caaaaactag
    15541 ctacattccc atggaaaaca gcgcttgtat agccttgctt ttgtccaagg atcgctggtg
    15601 cggcttgaaa gacattgtct gacccaagtt ctgtgaataa tgagccttga ggtaaaccaa
    15661 atgtgccagt ttccaacata ttttcagcat cacttgtctt tccctgtcct acttcatgaa
    15721 agaaattgtc aaagctgatc gttgcttgat tctggaaaat actatttaaa aacggtgtga
    15781 cttcttgtcc gtctaccttc atattaatca aaaactgctg gaaactttct aaatggagaa
    15841 cgatcacatt tttcccttta gcgatcccaa atgtttcggg atttggctct gcataatgtt
    15901 tctttgtata atctaaaact tcatcaatcc cattactgct tgcatgcgcg cgaacactgc
    15961 tagtcattcc tgttttgatt ccgtcataaa tagtatacgc atcgattcct agatatttga
    16021 caatatatga acggtcaaat gttcgctgca gcaattgtgg acggttggct tcgctcagcg
    16081 ctagatttcc tgaaaaaata agccctgaaa gacaggtaac agcgatagcc atcggtttgc
    16141 cgacagggtt gcttttgata ggtattttct tgaccttcaa ccaaaccagt agcccaatga
    16201 acacagcgat atccagccag tagatgacat catggggctt catcaaagaa aaggagcttc
    16261 ctgacaatcc ttgcgacact ttcgaaaagc ctaatacaga tttgactgta atgaaatctg
    16321 tgaattcccg ataaaaaata atattcaagt acaacaaaag cgtatttaaa atatcaatga
    16381 tcaaaagaat agctaacgct ggctttggct ttttaatata caaagaaagg ccaaaaaaca
    16441 ataaggtagt cgcaattggg ttgatccaca agataaagta ctggatcgta ccttccacac
    16501 ctaatgaaaa atctgcatag taggcaatga tcgtcttcag ccagaaaaag aaaacagctg
    16561 tcaaaacgat tgctaaacga ttttggcaca attttttaag ttgtgtcacg tatatcactt
    16621 ctctctattc acattttttc ttattttgct cctgaaaaat gaaaatttcc taaaaaagtt
    16681 gttatcttaa gattttttta ttctttctaa agattattcc gtccactttt cacagcataa
    16741 aaccgctgcg atgtaagcga ttaaactaat gaagagataa aagtcttgtg gtgaccgctt
    16801 cactccacgg tattcaaaag ccagtttctc ggtattcgta caaaaaaaga ggctgtgaca
    16861 aaattcttgt cgcagctcct tatttcttga tgcaggacag ctttttcaca acttcttcct
    16921 taaacggtgt tctcctgcca actcctcggc cacaagtcac aatatttata aaacatgaga
    16981 agctgttttt tgaaattgtt ccttgtggct cagagttaaa cggcaggctc aagacctctt
    17041 gatacacggt gttcaatcag ctgaccctcg gtattagatt atgtcaggac gctaatttta
    17101 caacctcttg gtaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
    17161 aaaaatataa ggagctattt tttgaaattg ctccttgtgg ctcagagtta aacggcaggc
    17221 tcaagacctc ttgatacacg gtgttcaatc agctgacctt cggtattagc tcaaaaaacg
    17281 gcaaaatatg aggaactatt ttgccgtttg tttctctaat actcaggtca aaacgctgat
    17341 ttcacaacct ctgtttttca ttgtccatag gattgatatt gtccttgtga tgactcattc
    17401 gtaataattg aggcttgatt ttcttcactt cccgttatcg tttgtccact gccagaatct
    17461 gaaggacttg ttcctgtcga ctcgtttttt tgagaagaga cagttgtttt cttgacttgt
    17521 tcatttgtct ttttccattc cgctaaacga tcggcgacca cttttttgtc tactttttca
    17581 gaataagcgg tgatcacttt tccatttttc aaacgggcta ctttgtcgcc atcatgagtc
    17641 aaaagcaaaa cggtcaaatg cttgtcttta aattgatatt gtctgagaga aatcgcacta
    17701 agtacgtcat cgatattaat aaattgattt tcttcttttc cttttggcaa ataaatgtcc
    17761 aattcgcctt tttcgtaatt ggcagttatt ttatactccg cccaccaata agttgagaat
    17821 tcttttttga aattatctac tgattctttg cttgctacga ttttttctgt ttctttctga
    17881 gcaagatctg ctgtcatttt tcctgaaaat gctgcggata aaataagcag taagaaaaaa
    17941 ccgaataacc aaaagagaag aaacggtctt tttttcctca tgctttcctc cactcctatt
    18001 taattttgac tattctatta tatacaaaaa atgaaataga aagacaaaaa agttgaaaaa
    18061 gatcgtaaat aattgaactt ctttttcaca aaatggtaag aatggagaat ttcacgcatt
    18121 tgctctcaac tattctttct taagcctcaa atccgttttt atctgatacg tctttgaacc
    18181 aatgacccga ttttttgatt gttctttttc catcttgtgc taagtctact gaaataaagc
    18241 catatcgatt cttatatgca ttggtccacg accagttatc catacatgtc cacatatgat
    18301 agcctaaaca attggcacct tcttgaatgg cttgatggac atatttcaga tgagattgga
    18361 caaattcgat ccgataatca tcgtggatca tgccatcttc tttgataaat cgtgcttcgt
    18421 tttctacacc cataccgttt tcagaaataa agcagtcgat atttccataa tgatctcgta
    18481 cattgatcaa aatatcatag attccttgtt catagatctc ccatccgcga taaggattca
    18541 ttttacgacc aggcatttca taattgtcga aataatcctc aggcattgga ccgtttttag
    18601 tatcgattgg tgtttctttt gcttttaccc ggcgtggctg gtaataattg atacctaaaa
    18661 gatctactgt attttctttg ataaccgtca aatcctctgc atggatcaca ggcatgagat
    18721 caagttcttt tactatctca atcaattcac ttggaaactc gccttttaca gctggatcaa
    18781 ggaatgaacg attgaagaac gcatctgcta tttgcgctgc tttaacatct tcagggtttg
    18841 attcgtctct tggatagctt ggtgtcagat tcaagatgat accaataaca ccaccttgct
    18901 ccatttcatg gtaagatttg atggctaacg ctgaagccaa cgcttcatga tagccaactt
    18961 ggatcgcttt tttcatatct gactcttctg gataatgcca tcgatataaa taacctgctt
    19021 cgactggaac gattggttca ttatgagtaa accatttttt tactttcgaa ccaaacaatt
    19081 caaaacaact tttggcatat ttttcatagg cttcaaccgt ttctcggttc aaccatccgc
    19141 ctttttcttg cagatacatc ggcatatcga aatgatacag attcacaaag ggttcgatac
    19201 cgttttcaat caactcatca aaataacgat gatagaaacg aacggcttct tcgttgattg
    19261 ttccagattc atcaggtatc aaacggctcc attggataga tgttcgaaat gaattatgcc
    19321 cagtctgttt catcaactgt acatcctctt gatacttcgt ataaacttgc gaggtttttt
    19381 caggtcctac ttgatcaaag aacttttgcg gttctttttt gtaccaataa tcaaaaatgt
    19441 tctctccttt tccatcgcct gaaatccttc cttctgtttg tgggccactt gctgcagaac
    19501 cccaccaaaa atttgctgga aattgatatt ttttcatcaa agcacctctt tttctttttt
    19561 agttcgtttt agttgattcc atgtatgata ttttccatca caatcacttt ttcattttct
    19621 tcctcttctt ttttgattcg ttttaacagc tgttctgctg ctcgttcccc gattttatct
    19681 gttggtggcg tgatcgtgat tttcggaagg atactcagat cgtttttatc taaataatca
    19741 tagtgactga acgcaatatc cttcccgatt ctgacacctt cttgattgaa acattcgatg
    19801 gcaccaatcg acatattgta attgctgaca aaaatagcag ttgccccttt ttctaataat
    19861 gcttttgccc cgtaatagcc gctttttcta gaatagtctc ctgtaaagac ctctaattgg
    19921 atcgatggat cattttggac cgcttctttg gctcctgcta aacgttctct tgctacgtag
    19981 tctgtttgag tggcagcaat aaatccgatt tttttatgtc cttgttcacc atgatgagcg
    20041 atcacttttg ctacactttc tcgatcattc actaatattg tatcaatacc tgctggtcct
    20101 tctggacaat tcaatgcgat aactggaata ctcatttttg tgagcatttc aaatccagac
    20161 cactcttctt cggataagaa gacaatcagc ccatcgatca catgcttcat caggtattca
    20221 attttttgtt caattttttc tggctgatcg gcaaacccgc ttaataataa gctataccca
    20281 ttttcttcag ctactctttc gatccctgag acaacttccg acccaaaacg gctggaaatc
    20341 ccgtttatca aaagtccaat agagaagctt cgattattct tcaacccttt agcaatgatg
    20401 ttttctttat agtccaacgc tgaaatcgct tctgctattt ttttcatgtt cttttccttc
    20461 agttgctgac cattcaagta acgggaaact gttcccactg aaacaccagc catcttagcc
    20521 acatcacgga tcgatgccat acattctcac tcctgccagt tacatttgat ttctctttct
    20581 tgttgttcga ttatgatgac cgcattcttt gcatagtgtt gcttgtcatc aatatccata
    20641 taactaaagt cttcagtaga gcaacttcct ctcactatta attatactta aacaagtatt
    20701 tgaaccggtt catttttaat atagcatttt tttaaaagat tgcaacactt ttttaaaacg
    20761 ctttctgaaa gtggcggatt ttttgccttt ttaaaatttt attctaaaat ttactctatt
    20821 tgtgggtgtt ttgtgcgttt ttctcttcca tccgtttgaa gttttacatt ccaatggtat
    20881 aatttcttta tcctatcaaa tgggggaagt attttgaaga aattaatcgt actatttatt
    20941 ttgtctgcgg gacttttgac attgactggc tgtgatttgt ttggcggctc tgaccaatcc
    21001 tcggacgaaa caaccgattc ttctgtctta aaagcggaaa aagcagatac caccaacagt
    21061 gtatatacgc taaaagtacg taaagatatg gatttatccg cgggacagtt gacatttaca
    21121 gataaaaaaa tggaatggac acgcacgtat cagacacaag gaactgattc ttctgaatca
    21181 tctgaagaaa aaacagtgct gacagatatc aagatcacta ccaaagatga cgaatatatt
    21241 atttcaggaa aagaaaataa aaaagaaaca acagtcatat ttacaaaaat cggtaattac
    21301 cgtttgaagg atgaggatgg caacatctac agtctatagt gccgtctgtt ggatcttctt
    21361 ttgtttctcc ccttcttttc tgctatagta aagaagcaag atgattgtaa aggagacgaa
    21421 atggatgatc gatagtcctg attattgtac atgtaataac aacaaaaata tccatacaga
    21481 atttaatgac caaggaagct tgagcatatg cgacaactgt cacaaactag tcaaagattc
    21541 atttaaaaca tttgaatctt atcctgttca aaattatgta aaaagtagaa gaagataaac
    21601 aaatccaagc aaaactcact atggctgatt tttatgaact tcaaactcag cttcttcctt
    21661 tgatcaagct tcatcagtaa aacaaacagt ggatcatttc agtttacaaa tcaaagagta
    21721 aagatttatt tatttcaaat atttgaatat aaaataacca aacgatagaa aggcttattc
    21781 tacatcacgt agtaattt
//
LOCUS       DAZKCH010000048        21553 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000048 DAZKCH010000000
VERSION     DAZKCH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.048"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(182..1081)
                     /locus_tag="ACG84X_001771"
     CDS             complement(182..1081)
                     /locus_tag="ACG84X_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9127638.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            complement(1091..1447)
                     /locus_tag="ACG84X_001772"
     CDS             complement(1091..1447)
                     /locus_tag="ACG84X_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFP9127639.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            1802..2098
                     /locus_tag="ACG84X_001773"
     CDS             1802..2098
                     /locus_tag="ACG84X_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFP9127640.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            complement(2621..3574)
                     /locus_tag="ACG84X_001774"
     CDS             complement(2621..3574)
                     /locus_tag="ACG84X_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9127641.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(3597..4352)
                     /locus_tag="ACG84X_001775"
     CDS             complement(3597..4352)
                     /locus_tag="ACG84X_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127642.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(4349..5308)
                     /locus_tag="ACG84X_001776"
     CDS             complement(4349..5308)
                     /locus_tag="ACG84X_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFP9127643.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(5301..6251)
                     /locus_tag="ACG84X_001777"
     CDS             complement(5301..6251)
                     /locus_tag="ACG84X_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFP9127644.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            6401..6853
                     /locus_tag="ACG84X_001778"
     CDS             6401..6853
                     /locus_tag="ACG84X_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFP9127645.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            complement(6942..9209)
                     /gene="gshAB"
                     /locus_tag="ACG84X_001779"
     CDS             complement(6942..9209)
                     /gene="gshAB"
                     /locus_tag="ACG84X_001779"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFP9127646.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(9396..10394)
                     /gene="ftsY"
                     /locus_tag="ACG84X_001780"
     CDS             complement(9396..10394)
                     /gene="ftsY"
                     /locus_tag="ACG84X_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFP9127647.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            complement(10405..11214)
                     /locus_tag="ACG84X_001781"
     CDS             complement(10405..11214)
                     /locus_tag="ACG84X_001781"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9127648.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            complement(11223..14804)
                     /gene="smc"
                     /locus_tag="ACG84X_001782"
     CDS             complement(11223..14804)
                     /gene="smc"
                     /locus_tag="ACG84X_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFP9127649.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            complement(14824..15510)
                     /gene="rnc"
                     /locus_tag="ACG84X_001783"
     CDS             complement(14824..15510)
                     /gene="rnc"
                     /locus_tag="ACG84X_001783"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFP9127650.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            complement(15858..17639)
                     /locus_tag="ACG84X_001784"
     CDS             complement(15858..17639)
                     /locus_tag="ACG84X_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9127651.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            complement(17665..18579)
                     /locus_tag="ACG84X_001785"
     CDS             complement(17665..18579)
                     /locus_tag="ACG84X_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127652.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            complement(18606..19568)
                     /gene="opp4B"
                     /locus_tag="ACG84X_001786"
     CDS             complement(18606..19568)
                     /gene="opp4B"
                     /locus_tag="ACG84X_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFP9127653.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            complement(19568..20512)
                     /locus_tag="ACG84X_001787"
     CDS             complement(19568..20512)
                     /locus_tag="ACG84X_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127654.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            complement(20513..21517)
                     /locus_tag="ACG84X_001788"
     CDS             complement(20513..21517)
                     /locus_tag="ACG84X_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127655.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
BASE COUNT         6012 a         4617 c         3810 g         7114 t
ORIGIN      
        1 ttcaaaaaaa gaatacacgc ttgcatctag tactctgcga gttacaaatc atccgatcaa
       61 ataaacattc gctgattatt ttccgcaaaa aaagcagcat atccacgata aatggatcta
      121 ctgctcttac ttatccttat gttttacaag gtattttctt ttacacatta ctaatgctgt
      181 ctcaatacgg aacgattgtc atcgcttgtt caaattcctc ttgcaaatgt tgtgtttgat
      241 aggcctgaaa agctgggtga tgggcacgca agaggacacg taatttcata ggatcatagc
      301 tgtctagcaa ctgttctttc aagacaaaat ctcgggtcag ctgccattca taataataac
      361 caaaaggtct gcagctgtaa atcgtgtgac cgatggattt atcttcaaag cgacgatgcg
      421 tatggccaaa aactacttgt ttgatatttg aataacggtc aagtaattct ccgaatgatt
      481 ctgatcctaa aaatgcattt aatttgttcc aacgctcata aggagcagat tgatacatga
      541 taaatgcccg tttaggaacg aaatgagtgg ataaaatcac ctcaagtttt tttgcttcca
      601 gctggtctag caaatttttt gcagctgcaa gcatttctgc attgacctcg agatctgttt
      661 tcccacgctg gatgaaccga tcataccaat acaaacgctt cattcgtacg attgcctcgt
      721 aatctttcaa ttcggaaaac tgatagtcgt accagccatt catccctaaa agaacggtct
      781 gctcatttaa agcaatatac cgttcattta aaaaatgtgg gtctggaaaa tggtccatca
      841 tctgttcatt gggcacatct gccaactcgt gattgccgaa atgaaatgtc gtagataatc
      901 ctttattgac gaaaaattcg acaacagcta ggcaacggtc tactttatta gccgtatctc
      961 cggctagatg aagccgagtg atcttgtgct tttgcaaaac ttgccaaagc tgcatcagct
     1021 ctgattcgcc gaatttattg atgtccacat gtaggtcgct gatgatcgcc aattttccca
     1081 ttttatccct ctagtctttt cgaacaactt gcaagttgcc ttttctcaag ccgcttggtc
     1141 cttttaattg taaactatta taagttggtt ctaaagcaag tgtggatgga tcatccatgt
     1201 aaagtattgc actgtctttg attttgattg gtccaactgg tgtatcagcc actacagaat
     1261 aaagacttag atctgtttgt gtatcttttt tgacaatgat caatcgaaat gccgtatcca
     1321 attggcaact gacttggctt tctgcaaatg gaccgtcacc gttttcgata tctaataaaa
     1381 gttgatcgtc tgcttctaat ttattcttca atacttcttg tgcttctttt gtcacttcta
     1441 atttcatctg tatcacctca tgtcatagaa taatcacttt attcatcaga tgcaactaat
     1501 ttgtctggtt ctgactgttc tcaatttatt ggaaagtaag tcattcgttt attatgattt
     1561 ctcttatcac aaaagagaca actttccctt ttcttcgttc agtttcttga acggaaaaag
     1621 acccaaaaag caacctgtta tttgtttaac cttattcctt tcttaaataa caaaaaatac
     1681 tataaaaaat aaaaaacctt taacaactat tggaaaaaga attacttttt gttcacggat
     1741 tattaacaac tcttcggtag agtaaactta tcaaataaaa gacttctttg gaggaatcac
     1801 tatgaaggaa tatataaaaa acatctattt tatcgaagaa acacaaaata tcgagggttc
     1861 ttatattgaa gtaaaaacac tctttgtcaa tgaagataaa accaaagcat tggatattta
     1921 taaaaaatta gcttcaaaaa aaacgaatag ttttggattg atattaagcg agtataaaat
     1981 caaagcagaa gagagttatt tctatcaatt actaaaacgg tggagtaagc ttcccgccga
     2041 tttttatcga aaaatgcaga tcatcaacta tcaaccgctt gctgagacac atgcctaaat
     2101 agaggttgtg aaatcagtgc tttgagctaa taccgaaggt cagctgattg aacattgttt
     2161 agaagagatt gtgacaactg cgatttgctt tgagtaataa gaacgctgga cagaaaatag
     2221 cttctcatat tttctagtct agtggactta ttgccgagaa gcagcagatg gaacatcgtt
     2281 taaagaagag atcggtacaa aataaaaata tctaaattta agttttatct aagtttcgct
     2341 ttgtaccttt gattcaaatc aaaggaggcg atcttgatgc tgaaaaaatg gatcacacta
     2401 ttttttgcca ctccccattc tagaatcaac ccgtatgatg tagataatga attcacgttg
     2461 aaaaaagatt tctcaaataa ataaaaacca tccgtaaaat catcaatacg attttacgga
     2521 tggtttttga taacttcttt gaggataggc tcttgctatt taagaatgta agaaacatta
     2581 ttgttacata gtatgagagt ttaatcctct gttatttatg ctatttaaat gcttgattca
     2641 catcttcgat catcagtttc attgattcta aaccgccccc gcttaaatac cagacatctg
     2701 gttcaaggga gatgatctgc tgatttttac cagcattcgt ttgtgctacc agttcattgg
     2761 cagaaatatc atctttgctg tcgtctccac caatagcttt tgttctgtct actacaaata
     2821 agatatccgg atttttttcc agcacatatt cataagaaac actttgaccg tgagtggatg
     2881 cttcgatttg atcatctgct tgttcaaagc caaataaatc atggatgaaa ccgaatctag
     2941 aaccagatcc gtaggctgat aattgccctt cattcacaag tgtgactagt gcttttttgt
     3001 cagtagcttc tgctttcttt ttcgtctgat cgattgcact agataattcc tctaattgag
     3061 ttttagcttc ttcttgctta ccaaagatct cccctaaagc agtgacattt tgctggaaag
     3121 attcccatgg atttttcgca tctaaagaaa ggaaaatggt cggagcaatt tgacttagat
     3181 ctttttgaaa atctctttgt cggccagaaa tgatgattag atctggctga agctgattaa
     3241 ttttttctaa gtctggttct tttattccac ctgctgattc tactttttta taggatgaaa
     3301 gatactcagg aaggctgctt gtagctgctc caactacctt atctccaaca ccaagagcat
     3361 ccatcgtatc taaagaacca ttgtcgaata cgacgacttt ttctggatta tttggcacct
     3421 cgatttggtc tccattacta tctgttatcg tcaatgtagt ttcagtttgt gtgctgcttt
     3481 tttttgtgtc tgcctgactg gtgttgttgc tatttccaca tgctgctaaa ccaaatgatg
     3541 ctagaatcaa gatacctact actaattttt tcatctcttc tctcctaatg ttagttttag
     3601 aaataaagac agaatctgcg gccttcaatc tcacaaatcc gtatgtccat ttcgtataat
     3661 tcatccaata catctttttt tatcatttct tgggtcgttc cttgcgtaaa taactgtcca
     3721 tctttcattg caacaatttc gtctgcataa cttgcagcaa agttgatatc atgaagaaca
     3781 ataacaattg ttttcccgat ttcttgtact aaatttttta aaatctgcat gatttgaacc
     3841 gcaaaattca tatctagatt gttcaaaggt tcatccagta aaatataatc cgtgtcttgc
     3901 gctagcacca ttgcaatata cgcacgttgg agttgaccgc ctgaaagagt gtcaatcgat
     3961 tgatccgcta tttcttctaa cccaatgtgt tccagtgatt cctgaacgat ttcctcgtct
     4021 tttgtcgtca attttccttt cgtataagga aatcgtccaa attctactaa ttctttcacg
     4081 gtgatttgga catttatttc attcgattgt cgtaggatcg ataatttttt ggctaattca
     4141 ttggatttcc aagcctttac ttcgttatgg tctaaataga tttcacctgt atcttttggt
     4201 atcaaacgac tgatcatcga caacaccgtt gactttccag caccatttgg accgataaaa
     4261 gcagtcaact tcttttcagg aatcgttaac tgtacatctt taaccactga ttttccatgg
     4321 tacagtttat tgaccttttg taaatcaatc ataggatact cttcctttcg cgaatcaatt
     4381 ttgtgacaaa ataaattcct ccgacaaatt caacgacgac actcactgtt gtattccagc
     4441 cgaaaatctg ctctactgcg agctgtcctc ctgtcagaaa cagcatagct accagaaagc
     4501 ttccgataaa tagctgacca tgacgataag tagaaaagac acgataactg atatttgcga
     4561 caataaaccc taaaaaagta actggaccca caagagccgt tgatgtccct gtcaaaagac
     4621 tgacacaaca taaaatcaaa aattcaaaac gatctgtgtc tatcccgagg tttactgctt
     4681 gttcatttcc gagatggaaa acgtctagca catgtcgata tcgaaataac aggtaccagc
     4741 agccgataat gatcaaagaa gcaggcaaaa gatactgact ctggatattg ccaaagcttg
     4801 caaataatct gccttgaagc aaatcatatt cattcggatc catgatgact tgtaaaaagg
     4861 tactgacact accaaaaagc gtacctaaaa tcatccctga catcagtaat aaaaaaagat
     4921 tcgctctcat ttttttcaaa agaaagaaaa ataacaatag actcagcccg accatcagcc
     4981 caacgttcaa taagaaaaaa actgtacctg tctgctgaag catcgtcact cctccgataa
     5041 agaagaaaag gaccgtttgg acaaggacat ataacgactc aagtcccaat actgaaggag
     5101 tcaaaaactg gttatgcgta attgtctgaa agctgattgt ggcactgctg acagctagcg
     5161 agacaaggat aaatgcaaaa attttcttac tcctcaatgc acatgcaaaa tgccagtttc
     5221 catatgtatg gatcgtcaag tacattcctg taacaaataa aacaagaaca agcataccaa
     5281 taaaaataga tggctttttt ttaagcatat cgtcgtcccc ttatcagaag ataaaggaag
     5341 atagccccac cgatgattcc aacgatcaca ctgactggta tttcataagg aaaaatcaac
     5401 acgcgagcga caagatcgca aaatactaag aacaaactac ctgctaaagc agttacgcca
     5461 attgttttgt gcacttgatc tccatatatt ctagagacaa gattcggaat gatcactccg
     5521 ataaaaggaa tgcttcctac catgatcaac atgactgcac tagccaatga tactaagcca
     5581 atgcctaaaa actgcatctt ctggtaatct attcccagat ttactgcaaa cgattcgccc
     5641 agaccaatga tcgtaaatcg gtaagcaaat agccaaacca agagcaacaa tggaacaaca
     5701 gcatacaata actcataatt tcctcgtatc acagtcgcaa aattcccttg aagccatgaa
     5761 gtcatatttt gtaccaactg gaattgataa gcaaaaaaag tagcaactga accaatgata
     5821 ttccctaaca tgactccaat caacggaagc atcaattgat ttttctggag gaacaatcgc
     5881 gtaagggata aaaaaagcaa tgttcctgca aaagcaaagc aaaatgctgt caaggatcgg
     5941 acaatcaagg atgcaccagg taggaaaatc atagccacta aaatacctaa acgcgcacta
     6001 tccatcgtgc ccgcagtcgt tggtgaaaca aatttatttt gggtcaaatg ttgcatgatc
     6061 aacccacaaa tactactggt cgctcccaca aggatcaaac aaatcgttcg tggcaaacga
     6121 gtcactagca agatttgtaa gctttgccca tctaactgga gcagttctga caattgtaca
     6181 ttcgatactc cgatgaacaa tgaaatacta cttaaaataa ctaataatgc tactagtcgt
     6241 ccgtagcgca tccaatccac ctttctaatt gagaatgatt ttcattctta ttttaagtga
     6301 atcgttgaac aaaagcaacc gctttttcat atgttttagg tattattggg aatatgctat
     6361 aatcgtaaga aagacaaaga gaagaaggag ggtatttttt atggcacaag atgatgtaaa
     6421 aagccatttg gataagggac tttatggtac acctttagtg aaccctgaag aacagcataa
     6481 atatttaggg acattcaggg aacgctgcta tcttagtatg actgttgctg aaatgatcca
     6541 accaaaaaac aaagaaaact ttttaaaaga actcaaaaaa catccagatg cttccatact
     6601 cttgaatggg gctctacccc tttctgtcca aaaccaatat atccagctag caacgaaaaa
     6661 caatagccgt ttcactgtag tcaacgatta cgtcactgca aatcctgagg aattcggatt
     6721 gctcttaaca gcaaaagaag cagtaaatga acctgtgatt gatatcgaaa aaaaataccc
     6781 agaagaaaac tcttcgccag ctgaaaaaga aaaaccaaaa aagaaaaaaa gcttctggga
     6841 tcgtttattt taaaacgaaa aaacacataa atttttacat gcaaaaaaag cttttgatca
     6901 gattgacatc aaataggaca atctgtcaaa agctttttct tttaaaatac ttcaggatat
     6961 aacaatttca atacattcat cgtcaatctt ctgccttttc ctgcaaaagg ataaacatgc
     7021 atatgcatgg ctggattgaa atttgcttcg atgatcccat atgctttttt atcagttgta
     7081 ggatcgattt ctttatctgg tataatcaaa tcgataccac taatcttagc tcctagtgct
     7141 tctaccgcag aaacggcgat ttttttgtaa gcttcagaaa attcatcagt catatcgatc
     7201 gaatcaccac ctgtactgat atttgagttc tcccttagat aaacaatttg attggcttgg
     7261 ggaactgatt cgatcgtcaa cccttgttct ttcaacatca attgttctaa ttcacctaat
     7321 tggatcaatt ctaaaggtgc acgatgattc gttccacgca aagggtcact atttttttct
     7381 tcaacaagtt ctttcactgt tcggatactg tcaccaataa cattagcagg gactcgcaac
     7441 atgatggctt ggacttctcc gtcgatcaca aagaaacgat attccgttcc cggcataaat
     7501 tcttctacta aaaccgaact gtcttcacga aaagcaatgg ctaaacctgc ttgataatct
     7561 tccagactag ctccttcctt gaaaatcgtg atacctaacc cgtaattggt tgatttaggt
     7621 ttgatcacaa atgcctgctc ggcaaatctc ggataagctt ttaccgcttc ttccatggat
     7681 gaaaattctg cgcctcctgg tacccggaac ccagcttctt ttaagacttt tttcgttact
     7741 gttttgtttt ccatgataag tgggacgata tagctgtcct tacttgtcat gtttgcattt
     7801 ttcacatatt ctacatggtc ttggaattgc agacgcaaaa attgatccga ctcatctaat
     7861 actttgactt ggacaccttt ttggatggca tcgaacataa atatctgagt agaaagttcc
     7921 atttcgcgaa aaccggccaa ctgataggga cgttcatggc tttctttata atattgatgt
     7981 cccaatgcca cagcaacttc ttgctgactc gatagctgtg cttcttgata gagtttcgct
     8041 gctaacgttt gttcaggatg atccatttga gtcaatgctt cctctactaa ataaagagaa
     8101 tccaaccaat ccaattcaac cagcatttgc ttcattcctt caagaatttc tctaccttct
     8161 tgatgaaatt ctgtttgatc tgatggttgt tctagtgcta ctttgttatt tcgagtcgta
     8221 ccttctgcta cccattggtc acagtcttct ttttcttctg tccataacat gtacatcagg
     8281 aataattgta agaaccgaac ttgctctgga ttgataccca atcttgcata aggattcaaa
     8341 tcgatattcc gcaattcaat ataacgaaca cctgttgttg ctaaatctgc gactttcttt
     8401 ccgcctcgga aacgaagcgg tgtataaaat tctttctcct ccgaaagttt cccttcttcg
     8461 atcattcgct cgatatctgc taaatactgt ttcatagaag cataggaaac tttcacattt
     8521 ggatgattcg tatagcccag cgcactgttg cgaatactgc gaacaggttc ttgcggatgt
     8581 gattcatcta aaaagtagtt cttctcactc attggtgaag caccgaataa ataagtgatc
     8641 atccagcgat agcgcataaa gtttctcgct gttttcaaat aaagttctgt tttgaattcg
     8701 gaaaaatctt gaaattcttc ctgatggctg aacaatgttc ttagcaactc atcgccaaat
     8761 tcaaaattga aatgaatacc gcttaccatc tgttttcgct tcccgtattc ttttgctaaa
     8821 taacgtcgat acaagacatc ttcgaaattt tttaattttg caataatgat ctcttcgtct
     8881 ttttccggta aggcaggtgg catacttaat ggccagatca tctcttcttt cggtatagaa
     8941 cgagcagtca catcataaac agcagcgaga tactgaaata attcgggaat agaatcggta
     9001 acaggggtga tcatctctgt ttgtgtttcg ctaaaatctg tttggatata ggggtgatag
     9061 gatcgatcgc caaagattgc tggatgatcg gtttttgcta gatttcctgc aagatcaacc
     9121 cgctgtcctt cccgttctat accaaatcga gcttggtcga taaaagggcg cgcattgaca
     9181 tgcaataata attgcttaaa attcatcatt aagtgacctc caattcatat gaatctaatt
     9241 ataatcaaaa agtctaagaa aaagaacgaa attgtttgag aaccgcttac aaataagtat
     9301 aaaaatgaag gcatcaaaaa cacagctatg ttaaaaacaa tcattcaaac aaggagctgc
     9361 aacttttgtc acagctcctg ctttttagac atgggttatt cttcttttag taatcctttg
     9421 aacaatccaa cgacaaaatc atttggatca aacggctcca agtcatcgat tccttcacca
     9481 agaccgacca atttcactgg taaatgcaat tcattacgga tagcaagtac gataccgccc
     9541 tttgctgtac catctaattt tgtcaaaaca agaccggtca catctgttgt ttctttgaat
     9601 tgttttgctt gaaccatcgc gttttgacca gtggttgcat ctaatacaag aagtgtttct
     9661 tggggtgctt ctggtaattc ccgctggatt actcgtttta ttttttctaa ttcgttcatc
     9721 aagttcactt tattttgcag tcggcctgca gtatcaacta gtaaaacatc tgcctgctct
     9781 gtctttgctc tttccaaagc atcgaatacg acagctgctg gatcgcctcc tgcattgcca
     9841 cgaacaactt caacaccagc gcgttcgccc cagacaacta actggtcgat tgctccagcg
     9901 cggaaggtat ctgctgctgc catcaatact tttttacctt cgtttttgaa ctgatgggca
     9961 agtttaccaa tacttgttgt tttccctaca ccattaacac cgacaaacaa aataactgtt
    10021 agtccgtctt cttggatatt tagttcattt acttcattga ttccttccgc ttcatagaga
    10081 tccacaagtt tctcgatgat cgcattttgg acttctgccg attttttcgc atttctgagt
    10141 ttcacttctt gacgtaatgc ttcggtgatt cgtatcgctg tttcaaaacc tacatctgca
    10201 ccgataagtg tttcttctaa ttcttcaaaa aagtcttcat cgactgttcg aaaattggca
    10261 aacaactcat tcatccgttc accaaatgtt ttacgcgtct tttctaaacc cttgtcgtac
    10321 ttctcctgta cttcaacttc ttctgttttc tcttcgccag taaaagcacg cttgatttta
    10381 tcaaaaaatc ccatttgact ccccctactc taatacaaat ttttggatca ctttggctac
    10441 gccattttct tcattgctgg ctgtcacgaa atctgctgct tctttgacga aaggcacagc
    10501 attctccatc gctacgccta gtccagcata ttggatcatc ggtaaatcat tttcctcatc
    10561 accgatcgcc atgatttctt cttgtttcaa accaagatct tttgccaata aagaaatacc
    10621 ataagctttt gtaacacctt ttggcataaa ttccaaaagc atacttcttg ttttgatgat
    10681 ctcatacatt tcatggaatt ctgctggtat ttctttgatt ttaggatcta attcttcttg
    10741 gtcataagcg attactgcct tattaagcac aaattcatct gtaatatcgc ttatatccgc
    10801 tggttggaat tgcagcagct tattcaacac attgtacaag gattgcttcc ttggggcact
    10861 aggcagctgt aaaaccacat tgtcagacaa aacatctagt ggcagatcca attgctgagc
    10921 cagtttgtat aagcgttgga tatctgatac ttccatcact ttcttttcca tgatttcacc
    10981 agtatcattt ttttgtacca aaccgccgtt gaaagtgatg ctgtagtcac cttcatctac
    11041 cagtcctaat tcttgcagat aatgcgccat cgcagctaag gggcgtcctg tacatagaac
    11101 gatcttgacc ccttgctgtt ttgcttgtgc taatgcttgt ttattctcat ctgaaatcag
    11161 cttttgttca tttaataatg taccgtccaa atcgattgct actaatttga tcattttcgt
    11221 tcctacactt tcgtttcgtt gattttcgcc tcttcattga tatcttccat ccgtacagaa
    11281 acgatttttg atacaccgga ttcctgcatc gtcactccgt acagtacatc tgctgcgacc
    11341 atcgttcctt tgcggtgtgt gactacgata aattgtgtgt catcttggaa atcgctcaag
    11401 taacgaccaa aacgtttcac gttggcttca tctaacgctg cttctacctc atctaagata
    11461 caaaacggaa caggacagac acggataatg gaaaagagca acgcgatggc tgtaagtgct
    11521 cgttctcctc cagaaagcaa acttagactt tgcagttttt tgccaggagg ttgtacttca
    11581 atctcaatac ctgttttcag caaatcagtt ggttccgtca gtactaattc agctttaccg
    11641 ccgccaaaca tatttggaaa gacaattttg aattcttgac ggatagcttc aaatacttct
    11701 ttgaatcttg tccgcacttc atcatccatc tcatccatcg tttcaaacaa ttggtttttc
    11761 gctgctaaca gatcatctcg ctgtgttgct aagaatgtat gtctttcact gacttgttcg
    11821 tattgttcga ttgaatttaa gtttactggt cccagttttt caatctgttc ttttaaggat
    11881 gaaacctttg ttctactgtc ttcgatatcg gttgtttctt gatagtcttg ggaagctttc
    11941 tcaaatgtca gctgatattc tgactgcaga taggtcaaat gattatctaa aatcatttca
    12001 gctcggtctt tttggacttc taatttggat tgttccgaca gtcgtgcttt ttgctcacga
    12061 ttacgctctg ccaagactgc ttcaagctta tcgatctcct tttgccttct atctcgctgc
    12121 tctttggctt ttgccaactc ggcttttaat gtttctcgct gagcagataa ttcgttaatt
    12181 tgtttttcca aactttcttc tgtgacttca tgatcagaaa agtctgctgt caatgtcgcc
    12241 aactgctttt ctatcgcttc ttgacgttcg gttgcctctg ctttttggac tcgggcaccg
    12301 cggagctgga tctgcagatg attaaactgc tctttcaaga cagcaagatc tgcttgttct
    12361 tgtgcttttt gactttgtac ttgtgctctt ctggcttcca tctggtcgct ttcttgactt
    12421 aacgatttga tttcttcgtc gattttttgt cgttgcgatt caagatctgt ttgtttgtct
    12481 ttcaattcgt tcgtttgctt ttcgtaatct tcgataaact gctgcagttc acgtgtctca
    12541 aaagttgaga tttgcttttc tttttcaaaa cgttcaagtt catttatgat gttttgtagc
    12601 tgatttgtcg cttcttgttc ttcaaaacgt aattgttcgc ctcgtgtacg caaaacttct
    12661 tgttcttcgg ctaaacgagc tgtttcttgt tgcagctcct gaactttttt ttcttgtgct
    12721 tggagttgtt tatctgcttc ttcaaattca ctagtcaact gtttcaattc ttgattttgt
    12781 acaaacaaac tgccttggtt tcctcgttta ttcgctccac ctgtcatgga tcctccggca
    12841 ttcatcacat caccttctaa ggaaaccact cgatattgat agcggatcgt ttgcgcgatt
    12901 gcattggcac tagttaagtc tttggctaaa aggatcgttc ctagcaggtt ttgaaccaca
    12961 gtttggattt gatcgggata actgacttgt tcactggcaa tccctataaa cccttctaca
    13021 gctgctgctt gtgtcaatat atgagccggt aattgtcttg gtttgattgt cgtcagtgga
    13081 aggaatgttg ctcttcctcc tctttgctgt ttcaaatacg tgatggcttg ccgagcatct
    13141 ttttcatttt caacgatgac atgctgggct gccccaccta aagctgcttc gatagctaac
    13201 gtgaaatctg caggaacatc gatcagttca gccactgctc cgacaatacc cgaaagctgc
    13261 tgtttatgct gcaagaccaa tcgaacccct tggtaaaaac caaaatagtt ttcttggatt
    13321 tcttgaaggc ttttcttacg agcacgtagc tgctggactt gattcattaa ttgatacatt
    13381 ttaggctgtt cttttgctaa tgcttcttgg aactttttcc cgttttgttg gatcatttct
    13441 aacttctctt ttgtttcagt taaagatgat tttagctgcg cctgcttttg tgtcaattct
    13501 tctttttgta agatcaatcg gtctactgat gcttctactt ccgattgctt ggctaacgtc
    13561 tgcttgcttt ttgctgtttc ttgtatatat tgacgttcta gatacttcag ttcgtttcct
    13621 acagctgctt gttcttgcat caaatcaaca tattgatctc ttaattctgc caataattct
    13681 ttcgttgatt tttggtattt ttctaattct tgctgtgttt ttatgagatt tgcttcagct
    13741 ttttggatct ctgtttcttt ttctgctgct gctttcatca agctttcttg aagcttttca
    13801 aaatgtttaa cctttttttg tgcttctgct aatgaagttt gatattcttg cgagcttttt
    13861 tgtgtatgct ttgtccgctc ctgcaaaaca tctttttgtc cttctgtctg cttcagtttt
    13921 tccgaaagat ctaataatac ttgctgattt ttttcgatca gacgatcggc ttgcgcattt
    13981 tctttacgct gcttcgccaa aatggattct tgttcttgga tcgactcaga tagtttgcct
    14041 aattctagat tgaatttcgc aagctgtgct tgtttgttgt cccaatcttt ttttgctgtc
    14101 ttgatttcag caaccatcaa agagacatcg gtttgagtca gtgtttcttt tagccgtaaa
    14161 aactcctttg ctgcctcact ctgggcggcc aaaggagtta actgttcttc caattcgtgg
    14221 atgatgtctt ggacgcggct gaggttgtct tctgtttcaa aaagcttctg ttctgctttc
    14281 tttttccgct gcttgtattt caagacacca gctgcttctt caaagatccc acgacggtct
    14341 tccggtttac tactgaaaat cgcttctact tttccttgag aaatgattga gaacgattct
    14401 tttcctaatc cagaatctaa gaacaattct tggatatctt ttaatctgca gctttgttta
    14461 ttgatgaaaa actcgctttc cccagtccgt cgataacggc gggttacact gatctcattg
    14521 tactccaatg gcagataatg atcactattg tctaaaatca ctgtgacttc tgcaatattc
    14581 agctgcttac gggtatcgga accggcaaag atgatatccg gcatttttcc gcctcgcaga
    14641 cttttagcag attgttctcc taatacccag cggatagcct ctgtaatatt gctttttccg
    14701 ctgccatttg gtccaaccac tgctgtgacg ctattttcaa aatcaatgac tgtcttgtct
    14761 gcaaatgatt taaaaccggc tatttcaatt cgtttcaaat acaaagcttt ccctcactta
    14821 cttttacagt gctgccaatg cattttccgc cgcagcttgt tctgctaatt ttttcgattt
    14881 cccttgtcca gtgccaatca attgatcatc tacataaact tcgatccaaa atactcgttc
    14941 atgagctgga ccttcttcat tgatcaatcg gtattcgatt gatacatcac ctgatttttg
    15001 caagacttct tgtagttttg ttttatgatc catctcatgt gaaaaagcac ctgctttgac
    15061 tttaggaaaa atcacttttt cgatgaatgc atgggtcgtg tcgaatccct ggtcaagata
    15121 taacgcgcct aaaaaagctt cgaataggtc gcaaagcaat gctggtcgcg tacgtcctcc
    15181 tgaattctct tctcccttgc ccaacaaaac atattgatca aagtgacatt ctttggcaaa
    15241 tttcgacaag ctgtcttcgc gaacgatcgc agctcgtgtt tttgtcaatt ttccttctgg
    15301 caaatgagga tataaacgga ataaatactg agaaaccatc agttctaaaa cggcatctcc
    15361 taaaaattca agtcgctcat tatccgataa ttgcagattg cgatgctcat tcacatagga
    15421 tgaatgggta aaagcttgtt caagcaaatt tagatcgtga aaaacgatgt tatagttttc
    15481 ttttagttct tttgtcagct ggttgtccat tttccacatt ccttttatgg atattttttc
    15541 gatacttcct tattatactg gttttttgtc aaatttgaaa tggttcggtc aaaaggtaag
    15601 taaagcttta ataatcctag tgattgacga gaagttgtga aaaattcgtt tagtttcgag
    15661 tatgaagaaa aaattttgtg aaaatggctt tccatatttt tgcataaatt tgacttaata
    15721 ccgagaaact ggactttgaa caccgtttat tggagaagtc atgaaatcag cgccttgacc
    15781 tgaatattag agaaataaac agaaaaatat caaaaaaccg aaaaaggaca tcgccctttt
    15841 tcggtcattt ttagtgatta tgaacgtgaa tctgctgtaa cagaaacatt tgcccatggg
    15901 tttggtacat cataagacca atcccagtct ttgacacggt cgttgactgg caatacttca
    15961 ttacggaaca acgttggaat cgcaaatgct tcttcaaatg catattgttg ccatttttga
    16021 tatgcttctt tttggtactc ttcatcaaat gctttgcttg aactgatatc gttgatcaat
    16081 tttgtatttt cttctgattc ataacgagtg tagttgaacg cagcatttgg tccccatagt
    16141 ccacttggat ttggatcagt tcctgtattc caagcagctt ggtaaacatc aatttcagga
    16201 tcatcgtttt ctaatttatc atagaaagaa ttgaattcga tcagacgacc tgttgtgtat
    16261 tggacatcca aaccaatttc tttccattgt tggatatagt aatctgccaa tggttgcgct
    16321 gtttccccac cggacatcga agcaaagttg attgttagtt tatttccatc tttgtcttct
    16381 cttaaaccat cgtcatccac atctttgtag ccagcatcat ctaatagttt tttcgctttg
    16441 tctagatctt gtgtgaatcc tttcatctca tcatcatggt atgactggaa tactggagga
    16501 atcaatgaag tcgcattgct tctcaaacct gcatagaaac gttcacctac tgcattatta
    16561 tctaatgcat agcccattgc ttgacgtaat gatttatcag ccatttttga atctggattg
    16621 tattccacac tctttgtatc tgcattccat ttacctaact tgaatcctag ataagtataa
    16681 gaagtttgtt cacggcctaa gtttgtatag ccagcaattt ctttataggt atcgtaagta
    16741 tctgttggca tttggaaaat catatcatat aatttagagt tcaatgcttc agttgcactt
    16801 gccatcggta cagatttcat cgtgatcttt ttcaatttag gcgtaccatt ccagtagtgc
    16861 tcgtttggca agtattctac tgattctcct gcaacgatat tactcatgta ataagggcca
    16921 aaagtcactg gatttttacg tacttgatcg cttgattcca tatctttgat tgctacacct
    16981 tctaacgtat gttttggtgc tgcatatgac cagataccac cacccgattg aagcatgctt
    17041 gggtttactt ctttatattc gatttcaact gttttgtcgt ctattttttt gattccggag
    17101 attgtgtcgg cacttccatc atgatattct tccataccta cgatgttacg gaaagtgtcg
    17161 tcataacgga taccagtgta atctttattc ccaatgattt cgtaagggaa aatcacatcg
    17221 tccgccgtta catcttcacc atctgaccat ttgacgttgt cttttacttt gattgtcgct
    17281 tttttcgtat cttcatctag atcaagcgtt gcagctccgt cgtctgtgat tctgaaatcg
    17341 tcatcgtttg caaatagcgg ttcatgagaa ggagccataa aagctgcatc atatgaatct
    17401 tggtaaaact cccactggaa caatccttta aactgactgt ccgttgcgac cgcagcttct
    17461 aattcgccgt cttcgattgc atcatcatta ttttttgttg caattggaaa agttaattcc
    17521 tctttgttat tgccgttgcc tccagagttg tttccagagg tatctgtacc tccgcccccg
    17581 catgctgcaa gaacgacagc agacatcagc gctgcaaatc caaaaatcgt tttcttcatt
    17641 cctatttccc ccttcgcttc tatactagcc taaccgttgg cgcgcatctg cagaacgctt
    17701 gaatgcttgt ccaacataat tgatactcaa catcaaaact aaaataagga ttgatgcggg
    17761 taaccagatc cattgccgat tcactaagac ttctccgtta cttgcataac cgatcaatgt
    17821 acctaaacta ggtacatttg ccggcaagcc gaaacctaag aaagtcaaag ttgtctcgat
    17881 accgatgttt gccgcaaagt tcatcgtcaa attagtaatg attaatgaac ttagattcgg
    17941 catgatttcg cggaacatga ttttaaaatc attggttccc attgtttttg aggcactgac
    18001 ataatctctt cttgcttcag ataatgtctt gcttcggaat aatcgggctt tagctaccca
    18061 ataaaatgca ctcatgatga atataaagga ccagacattg tatctggaaa taatcgatac
    18121 gaagacgata atgatcagca tgatcggtag aatcatgata aaatcaacga tccgcatcaa
    18181 gatgttgtca atgatccctc cgtagtagcc agagatgatc cctaatccaa ccccgatgat
    18241 cgaagtaagg atcgtgatcg caaatccgat cgtaacagag tttctagcac ctatgatcaa
    18301 ttgtcctaat acatcacgtc cgccttcatc tgctcccaga atgaactttt gtccttgtgt
    18361 cgaaactgtt cctggtgcag cgtatttgtc gaagatacta acatacatca ctttgtcttg
    18421 atcggtcagc atcgcaccga taaagatcac taataataaa accactagca aacctaatga
    18481 aaaaatagca attttatctt ttttaaattc tcgagcaatc attcgtatcc ccataggagg
    18541 aatactttct tgaactgctg tattgttttt ttcactcatc gatccattct cctttctgat
    18601 tggttttatt gaatccgaat acgcgggtca acgatactca tgatgatatc tgaaagtaat
    18661 gtccccacta gcgtcgcgat tcctaaaatc aatactaagg atgtgatcac ggtatagtcc
    18721 cgttggccga tggaatcaat aaatagtttt ccgactcccg gataaccaaa aatcttttcg
    18781 ataactacag aaccagcaat caacgaagtg atttcatacc ccatttgaga agccatcggc
    18841 aacgctgcat ttcggaaaat atgtcgactg aatactttat tcgtcggtac ccctttggaa
    18901 cgggctgttc tgacaaaatc gagcgatttc gaatcgatta cttcacttcg cagatattgg
    18961 attgtgacgg cagtcgccaa aaatgcttgg gtaattgatg gtaacagaat atatttcaaa
    19021 cggtctatcc attgagtgat aaatccacct tgcaaaccta gtgtttgtga tccacttgtt
    19081 gggaaccagc ctaaacgata accaaaaaca aatagcatga tcaagccgaa gataaataaa
    19141 ggaacagcaa aactaaagaa gttgtagatt acgacaatct tatccaagat tgaattttga
    19201 taccggccag caagcatccc cagaggcaca gcaatcaaat aagtaaggac aactgtcaag
    19261 atcgatagat ataaagtgtt gatgatccgt tcgccgatca agtcagcaac agagcgtttg
    19321 tataagaaac tttgaccaaa atcgccttgc aaagcatttc cgatccaacg gaagtactgg
    19381 acataccatg ggtcattcaa gccagctgct tgtcgcatct gttcgatcac tgccggatcc
    19441 tgatttggat tgatcaaacc ggtaaatgga tcccccggca tcgcttgggc taataagaag
    19501 atcagaacac ttaaaataat aacttgcggg atcatcaata aaacacgtcg cagaatcgtt
    19561 ttccacatta gcttgcacct ccatctttca acgccacttt gtgtgtagtt gtgatcgtac
    19621 gcaaatcgta gactcgacca gtcgcatcat agtattcttt ttggttttgg atatactctt
    19681 gttctactct tcgtcgattt tctttgtggc tttccctatt ttctacatcg atttgcggaa
    19741 tagctgaaag cagacgtttc gtatagatat gtcgcgggtc attataaatg tcttctcttg
    19801 taccgatttc tacaaatcga cctttgtaca taattgcgat attgtcgcac atgtgtttta
    19861 ctacacctaa atcatgtgaa atgaataaat agctgaggcc gtattcttgc tggattcgtt
    19921 tcatgaaatt caatacttgc gcttgaacag atagatccag agcagataca ggttcatcgg
    19981 ctacgatcag ttttggattg gtagcaacag cacgggctac tcctagacgt tgacgttgtc
    20041 cgcctgaaaa ttcatgagga tatttatata gcgcatcttc cggcatccca acgatatcta
    20101 gcagtccttt tacctttttc ttttcttctt gatcgcttaa ccgttcaaaa tttcggatgg
    20161 gttcagcaat gatatccaac actcgctttt taggattcaa actggacatt gaatcttgga
    20221 agatcatctg cacatccttg ttataaccca tttttttgcg gttgcttcgc ttcgttacat
    20281 cttttccttc atacatgatt tgtccggctg ttaccttttc taatcccaca acggcttttc
    20341 ccgtagtaga ttttccagag ccagactctc ccactaaacc atatgtcttt cctttttcga
    20401 taataaaatc cacaccatct acagcatata catgatccgt tactcgattg aagaatccac
    20461 tgcgaatagg gtaatgaact ttcaggtctt tgattgtgat taattctgtc atctacacct
    20521 ctcctttttc gtctctaaag tggaaatgct tatagcagga gcaacgtacc aagtggttcg
    20581 gtgcgacttc atgaaggata ggctcttctt catgatcgct tgctggtatc catggaatac
    20641 gtggtgcaaa ccgacaacct ttacgaggca tgtttttcag agaaggaacg acaccttcga
    20701 tcacatggag ttctgcatca tgatttcctt cttgtggtat agagttcagt aaagagcgtg
    20761 tataaggatg cttaggatga tcaaacagtt cttttacacc tgctacttca acgaactgtc
    20821 cgccatacat cactgccact cgatcagcca tttctgctac gactcctaag tcatgagtga
    20881 tcaagatgat ccctgttttt gtttcttcct gaaggtcttt cagtaaatca agaatctgtg
    20941 cttggatggt tacatctagg gctgtcgtcg gttcatctgc aatgacgatt ggaggtttgc
    21001 aggcgattgc gattgcgatg atgacacgtt gtctcatacc gcctgatagt tcatggggat
    21061 attggcgtcc aactctcgca ggattaggaa tccctacttg ttctagcaat tctagtgcac
    21121 gagcttgacg ctgttctgca ttcatctttg tgtgatagga aagtccttct ttgatctggt
    21181 cttcgattct catgagagga tttaatgcag acaacggatc ttggaaaatc attccgatat
    21241 catttccgcg gattttatta tagagcgttt cgttcaggtc gattaaattc agatcgttat
    21301 ataaaatctc acctgtaatt tttgtgttat taggatcaag taatcccata atcgtagtag
    21361 ccaaggtact tttcccgcac ccagattccc caacgattgc taaaatctcg tttttgtcta
    21421 aagtaaatga aacgtcatct actgcatcgt aatagtcatc tttgagtcgg aatcctgtat
    21481 gtaggttctg aacttctaat aattggttat cggacaatcg aatacccctc tctgcttcct
    21541 aaatggaagt ttt
//
LOCUS       DAZKCH010000049        20741 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000049 DAZKCH010000000
VERSION     DAZKCH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.049"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            3..1088
                     /locus_tag="ACG84X_001789"
     CDS             3..1088
                     /locus_tag="ACG84X_001789"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFP9127656.1"
                     /translation="MILTPVFKIISVQTGMVDKPNERRINKVPMPSAGGLPIFISFVI
                     STLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPKQKSIGILIASLIIYFVAD
                     IRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDGLDGLAAGISLIGLITIGI
                     IGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLGDTGALFLGFMMAVLSLQG
                     LKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTADKKHLHHRLISLGFTHKG
                     AVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAILLFELIGLINEKHQFILKT
                     LRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            1081..1881
                     /locus_tag="ACG84X_001790"
     CDS             1081..1881
                     /locus_tag="ACG84X_001790"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9127657.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            1881..2708
                     /locus_tag="ACG84X_001791"
     CDS             1881..2708
                     /locus_tag="ACG84X_001791"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9127658.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            2713..3420
                     /locus_tag="ACG84X_001792"
     CDS             2713..3420
                     /locus_tag="ACG84X_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9127659.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            3520..4386
                     /gene="rfbA"
                     /locus_tag="ACG84X_001793"
     CDS             3520..4386
                     /gene="rfbA"
                     /locus_tag="ACG84X_001793"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFP9127660.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            4400..4972
                     /gene="rfbC"
                     /locus_tag="ACG84X_001794"
     CDS             4400..4972
                     /gene="rfbC"
                     /locus_tag="ACG84X_001794"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFP9127661.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            4994..6022
                     /gene="rfbB"
                     /locus_tag="ACG84X_001795"
     CDS             4994..6022
                     /gene="rfbB"
                     /locus_tag="ACG84X_001795"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFP9127662.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            6120..6971
                     /gene="rfbD"
                     /locus_tag="ACG84X_001796"
     CDS             6120..6971
                     /gene="rfbD"
                     /locus_tag="ACG84X_001796"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFP9127663.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            7005..9038
                     /locus_tag="ACG84X_001797"
     CDS             7005..9038
                     /locus_tag="ACG84X_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127664.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            9082..10362
                     /locus_tag="ACG84X_001798"
     CDS             9082..10362
                     /locus_tag="ACG84X_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFP9127665.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            10572..11378
                     /locus_tag="ACG84X_001799"
     CDS             10572..11378
                     /locus_tag="ACG84X_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127666.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            11390..12610
                     /locus_tag="ACG84X_001800"
     CDS             11390..12610
                     /locus_tag="ACG84X_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127667.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            12600..14186
                     /locus_tag="ACG84X_001801"
     CDS             12600..14186
                     /locus_tag="ACG84X_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9127668.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            14225..16363
                     /locus_tag="ACG84X_001802"
     CDS             14225..16363
                     /locus_tag="ACG84X_001802"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9127669.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(16731..17714)
                     /locus_tag="ACG84X_001803"
     CDS             complement(16731..17714)
                     /locus_tag="ACG84X_001803"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFP9127670.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            18092..19483
                     /locus_tag="ACG84X_001804"
     CDS             18092..19483
                     /locus_tag="ACG84X_001804"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFP9127671.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            19499..20539
                     /locus_tag="ACG84X_001805"
     CDS             19499..20539
                     /locus_tag="ACG84X_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9127672.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            20558..>20741
                     /locus_tag="ACG84X_001806"
     CDS             20558..>20741
                     /locus_tag="ACG84X_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFP9127673.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFV"
BASE COUNT         6648 a         3438 c         4275 g         6380 t
ORIGIN      
        1 cactgatatt aacacctgta ttcaaaatca tttcagtaca aacaggtatg gtcgacaaac
       61 caaatgaaag aagaataaat aaagttccaa tgccttcagc gggcggactg cctatcttta
      121 tttcatttgt tatatcgact ttattcttat tccgtaaaat tatccctcaa tcgtatattg
      181 taccgatctt gattgcttct ttagtaatca tagtcacagg agtgctcgat gataaatatg
      241 agctgacacc taaacaaaaa agtataggga tcttgattgc ttctcttatt atttattttg
      301 tagcagatat acgtattgat tccttcacgc ttccttttat tggatatatc caactaggct
      361 ggcttagttt tcccgtaacg attttttgga tcttcggtat cacgaatgcg gtcaatctga
      421 ttgacggttt ggatgggctg gcggcaggga tttcattgat cggtttaatt acgataggaa
      481 tcattggata ttttttcctc catgcttcta cagtgtatat tccagttgtt attttctgtc
      541 ttgtagcaag tattatcggt ttttttcctt acaattttta tccggcaaag atttatttag
      601 gcgatacagg agctctattc ctagggttta tgatggccgt cctttcacta caagggctga
      661 agaacgtgac ttttgtttca tcgatttctt tgctgatcgt catgggagtg ccggtaacag
      721 acacgttttt tgctatcatt aggagaaaag caaaccgtgt ttctttttct acagcagata
      781 aaaaacatct tcatcaccga ctaatcagtt taggctttac tcataaaggt gctgtcctga
      841 cgatttatgc gatggctttg atgttttctt tcacagctat ggtcatgaat tatactggaa
      901 gaatcggaac gatcatattg attattgcca tgttgtttgc tgcaatttta ttatttgaat
      961 tgattggtct gatcaatgag aaacatcagt ttattttaaa aacattgcga tttttaggga
     1021 ataaagagta ccgtacgcaa gtaaaacaga aatatttgaa gaaatggaac cgtcatatag
     1081 atgaataaca aattaaacca gccgatcctt attagtattg tgacggcaaa cagtgataaa
     1141 atttttcgga cactagataa ttttatttca actgtaaaag atgaaacagc agtaaaaatc
     1201 cgaatttttg acaacaattc acttcccgag tacaaaaaaa gactaacaga gtataggaaa
     1261 tatccctaca tcgatatcta ttttcatgat gaaaattccg gatttggtta tggacataat
     1321 cacaatctga tagctagcga ttctcgctat ggcattattt gtaacccaga tattttagtg
     1381 gatgaagaga cagttacagc attggtcttg ttattgaaag aacatccgga atgtgcgatg
     1441 ttagcaccta agattcttaa tgaagatgga acaactcagc acctcatccg tgagcagctg
     1501 gctgtttttg attacgtttt gcgctttgtg cctttcaaat gggtcaaaaa aaagtttgac
     1561 aaacgactgg ctgtgtttga atgccgagga ttgcctactg atgctaatag ttatgtacgg
     1621 atgatctcag gtagttttat ggtagctgat attgataaat ttaaagagat aaaggggttt
     1681 gatgagcgtt tcttcatgta ctttgaagac aacgacttgt gtttgagttt tgaaaaagca
     1741 ggttacaagt tattgtacac acccttttat gcagttatcc atttttacgg gaagggtgcg
     1801 catcgaaatg caaaactgtt tcgcgtgttt ttgacttcta tgatgaaatt tttcaataag
     1861 tgggggtggc gttttttctg atgaaaccag aaatattagt agtcgttgtg ctttatcagc
     1921 aactattcag tcaatctcca gcttatggac cattaagcaa agcacttagc gaaaagcaaa
     1981 ttcagcttat tatttacgat aatagtcctc aaaggcagca aaatgagctg tttgaaaaag
     2041 aaaatatcgt ttatcatcat gatccgcaaa atcctggttt agcggtggct tataattttg
     2101 cgttgtctca agcagatgaa ggaacacgtt gtctcgtcac tctggatcag gatacgaggc
     2161 tagtcgacga ttattttgaa ctattgcgta aagtaacctt tacagatgaa tgtgttgctg
     2221 cagttccgat gattttttct gggagccgac aagtttctcc cctatattca gatcgttata
     2281 tcaatcgtac agctcaagca gtagaagttg aaggcccaac agctgaacga atcatggcaa
     2341 tcaattcagg tgttgcctgg tctgtcaaat ttctaaaaaa gattggcggg tttaatcctg
     2401 ctttttcttt agattttttg gatcattggc tgttttggaa agtggatcag ttggaaaaaa
     2461 ctgtggagat ccttcctgta cgaatggaac atgatctttc ggttttagac tatgaaaaag
     2521 tttcaagtaa tcgataccgt tctattttac aagcagaaaa tcgattttat catgaatatg
     2581 atcaaaggca tttatccagt caccgacgac aattattgtt aagaacagct aaacagttct
     2641 tgaccgtcaa aaaccggcat atctggcgga tgactttgcg ctcatatgtt aagaattgga
     2701 aggtgtgaat tcgtgcgttc ggtttgtata gctaccttta atggaggcag atatttaaga
     2761 gagcagttag atagtatttt atctcagctt tcagcagaag atgaagtagt catttctgat
     2821 gatgggtcag tagatgatac atgggatata ttaactgaat acgcagaaaa agataagcga
     2881 atccagcttt tttcggggcc tcgtcaagga ttgatcgcta attttggtta tgcgatccag
     2941 cagacgaaag gagatctaat ctttttggca gaccaagatg atgtttggtt ggagacaaaa
     3001 gtgaaaaaga tcactgacta ttttgagcag aatccggatc agctagtagt agtttctgat
     3061 ttaatcattg tggacagcga gctgcaagag atccatgatt cgtatttttc gtttcgaaat
     3121 tccaaagaag gatggcttaa taatgtgata agaagtcact atattggtgc tggtatggct
     3181 ttccggtctt ctttaaaacc cgatattttg ccgatcccgt cagaagtgcc gatgcatgat
     3241 atgtggattg gtttgctggg aggaaagaag actgggttcc taagagaacc gttaactctg
     3301 taccgaagac atgatttaaa cgcgagtgag attgaaacac attctaaatt acggcaaaaa
     3361 atttcttggc gtgttcatct gattacggcg ttgatcaaac gaaaatggtt taaacgttga
     3421 taaaagatgt ttaaatcctt aatatttcca tgacaaatat aacaattgat gagataataa
     3481 caaagtgaaa tttgaaatca aaaaggagag cagatatcca tgaagggaat cattcttgct
     3541 gggggcagcg gaacacgtct gtacccttta acaaaggcaa catcgaaaca attgatgccg
     3601 atttatgaca aaccaatgat ttattatcca atgtctactc tgatgttggc gggaatcaaa
     3661 gaaattctga ttatttcaac gccacaagat acaccacgtt tcaaggaatt atttggaaac
     3721 ggaaatgatt taggactgca gatcgaatat gcagtacaag aaagtccaga tggattggca
     3781 caagcgttta tcattggaga agaatttatt ggagatgata gtgtctgctt ggtattaggg
     3841 gacaatattt actatggtgg cggtctgtct aaaatgttgc aacgagcagc ttcaaaagat
     3901 acaggcgcga cagtatttgg ctatcatgtc aatgatccag aacgctttgg tgtagtagaa
     3961 tttgatgaga atatgcaagc tttgtcgatt gaagaaaagc ctgctcagcc aaaatcaaat
     4021 tacgctgtaa ctggccttta tttttatgac aatgaggtaa tttctatcgc taaaggtatc
     4081 aaaccttcag aacgtggaga actagagatt acggatgtca ataaagcata tttggataaa
     4141 ggaaaactat ccgtagaact tatgggacgc ggatttgctt ggcttgatac aggaacacat
     4201 gaatcattgc ttgaagcatc tacctttatc gaaacaattg aaaaacgtca gaacttaaaa
     4261 gtggcttgtt tggaagaaat tgcttaccgt atgggctaca tcgataagga acaattgctg
     4321 gcccttgcac agccattgaa aaaaaatcaa tacggtcaat atttattgaa tttggccgct
     4381 gaataaggag tccttacaga tgaaagtaac agatacaaaa ttaacagatg tcaaaatcgt
     4441 agaaatggac gtctttggcg atcatcgcgg tttcttcaca gaaagttatt caaaagcaaa
     4501 atttgcagaa catggattga aatatgactt tgttcaagac aaccattcac tatcagctga
     4561 agctggtgtc cttcgggggc ttcatttcca aaaaggagaa gctgcacaga caaaattgat
     4621 tcgggtagtc actggagcag ttttagatgt agtagtggat atccgcaaag gtagcccgac
     4681 ttatggtcaa tgggacggat ttatcttatc tgaacataat catcgacagt tgcttgtacc
     4741 taaaggatat gcccatggat tcgttacttt gacaccaaat gtgaacttcc tttataagtg
     4801 tgataattac tataatgcag aagcagatgg gggcatcgca tttgatgatc cagatttagc
     4861 gattgattgg ccaattgatc catcaagagc gattatgtcg gaaaaagatc accgtcatcc
     4921 gacattaaaa gaatttgaag cagaaaatcc atttgtttac ggagaaatct aagaattaag
     4981 gagaaatttt cttatgaaaa acatcattgt taccggaggt gccggattca tcggctctaa
     5041 tttcgttcat tacgtggtaa acaatcatcc agaagtgcat gtcactgttt tggataaact
     5101 gacttatgca ggaaacaaag agaacttggc tggacttcct agcgatcgcg tagaattggt
     5161 cgtaggagat gttgcagatg cagaattagt ggaccgtcta gtaaaagaag cggacgcagt
     5221 tgttcattac gcggcagaat cccataacga taattcatta aaagatcctt tcccatttgt
     5281 acaaacgaat atcattggta cgtatacact tttagaagct tgccgcaagt atgatgtacg
     5341 ctatcatcac gtatctactg acgaggttta cggcgatctt ccattacgtg aagacctgcc
     5401 aggacatggg gaaggcgaag gagaaaaatt cactgcggaa acaccatata atccttcaag
     5461 tccatattct tctacaaaag ctggttcaga tctgttagta aaagcatggg tgcgttcttt
     5521 tggcttacgt gcaaccattt caaactgttc aaacaactat ggtccttatc agcatattga
     5581 aaaatttatt cctcgccaag taacgaatat cttaagcggt attcgtccaa aattatatgg
     5641 cgaaggaaag aatgttcgtg actggatcca tacgaatgat cattcttcag cagtgtggct
     5701 gattttgacg aaaggcagaa ttggcgaaac ctatctgatc ggtgcagacg gtgaagaaga
     5761 taataagacc gtgatggaat tgatcttaga aatgatgggt caaccaaaag atgcgtacga
     5821 ccatgtaaac gaccgtgcag gacacgactt gcgttatgca atcgattcga caaaattacg
     5881 ggaagagtta ggatggaagc ctgagtttac gaacttccgt gatgggttgg ctgacacgat
     5941 caaatggtac gaagaacatg aagactggtg gaaaaaagaa aaagaggccg ttgaagcagc
     6001 atatgccaaa aatggacaat aatacagaga aaatgtcact gtattaatgg aaaaacacat
     6061 gtgaggcagg cgctcgcctg tctctttttt aaaataaaaa tcaaggagcg gataatcata
     6121 tgtttttatt aactggagga aatgggcaac taggtacaga attgcgccat ttattagatg
     6181 aaaaaaatct gcaatatgtt tcaacagatg caaaagactt ggatatcaca gatgccgaga
     6241 aaacaatggc ttacatcaca gaattaaaac ctgatgttat tttccattgt gcagcttaca
     6301 cagcagtaga taaagcagaa gaagaagcaa aagaattaga tgagaagatc aatgttgatg
     6361 gtacaagaaa tgtagcactt gcagcaaaag ctgtgaatgc tcaattcgtc tatatcagta
     6421 cagactatgt tttcgatgga aaaaacaaaa atgtagaata cgaagtagac gaccaaacga
     6481 atccactaaa tgaatatggt cgtacgaaat tattaggcga aaaagcagta gaagagattt
     6541 tagaagacta ttatatcata cgaacttctt gggttttcgg gatctatgga cacaatttcg
     6601 tcttcacgat gcaacgccta gcggaaaccc gcgacaaact gactgtagta aatgaccagt
     6661 ttgggcgacc aacttggaca cgtactttgg cagaatttat ggtatatgtc atcgaagaaa
     6721 aagcaccatt tggtatttat catttgtcga acgaaaatag ctgttcttgg tatgaattcg
     6781 caaaagaaat attgaaagat acagatgtag aagttgcacc tgttacgtca gaagaatttc
     6841 cgcaaaaagc aacacgtccg cagtattcag tcatgagcct gaaaaagaca gaagagttag
     6901 gatttgtcat accaacttgg caagaagcac ttgcgcaaat gctggaagct gccaaaaaaa
     6961 tgaataagta atttcctttt atcaaataga atttggagca tgatatggaa aaacaaacaa
     7021 gaagtgcacg acgaaaagaa aagccaaaag cgaaccaggc agattcgaat ttggtgcttg
     7081 acctgtttct aaaactccgc tatcttattg gcgttttagt catcgtggtc atcgttactt
     7141 ttaatttaaa cggaagttca cttggtgttt gggataaata tgtgtcgcaa agagacgatg
     7201 ggaaaaaaac tgatgtgatt tttggacaga atcgggaagt gcggtcagac gaatggctgg
     7261 tgcagacacc tttttacctc tcacaagctg aagaggactt tccgttggtg aacgaggatt
     7321 attcattaaa cggacaaaac atgatcattg cgtataattc tcctgtaaag gatattacgg
     7381 ttatcggaaa accattcaac tggggattct ttttcctcgg aagagatcga ggactttcct
     7441 tttattgggc gatgaaatta gtcgtcatgg tcttgcttgg attcgaagta ctgatgatat
     7501 taacgaagag aaaaaaagct ctatcgctaa tcggtgcatt tgcgctgaca ttttctccag
     7561 cagtccagtg gtggttcatg caacatgtgg gcgatttgat tttctttact ttgggactga
     7621 tgactgcttt ttatcattat ttctacaatc atgataaaaa atggctacga acgttgatga
     7681 tgcttttggt ggttattttc ggtattgggt ttattttagt gatttaccca gcccatcaag
     7741 tgatgctggc gtacttgctg attttttatt ttgttggcct gcttatttac tatagcaaga
     7801 aagtttcatg ggatctgttg gatgtagtgt tgattggagg ggcagtttta tttattggcg
     7861 gagtcatggt tcatttctgg ctaacgtcaa aagacgcatt gttagcttct ttgaatacct
     7921 tatatccagg aaaacgggta agtactggag gaaagtggac gattggcgaa tttttttctt
     7981 tccttacaaa ttggaaaatt ccttttgaag atatcaacta ttcgaataac tctgaagtgg
     8041 ccctgttcta tcactttttt ccaactgtat tcctagcaag tccatttgtg ttatttggca
     8101 aaaaagatag cgaacaaaag ttactgggac gtattttgat gattttttgt ctgttttcta
     8161 tcttttggat taccgttggg ttgccaaaat ggctagcaga aatcactctg ctgtcttatg
     8221 ttcctccatt aagagccatc cttactttta gttttgcggc ttgtttatta tcgatctggt
     8281 ttatcgctta tatttggaga gaagatgtta ttcctatttg gtataaattc attttgttgg
     8341 cagtaaatgc atggtcttat ttctatgcga ttacgcattc gaaaatggat aattattttt
     8401 cggattttga aaccatcgca gttgctgtgt tgggaacagt gattttagct tttgcattat
     8461 ttggctggag acgcttgttt tacctcgctt ttgccgcctt agttatcgta tctggctttt
     8521 tcgtcaatcc agtcgtagaa ggtacaggag cgatttttga aaaaacactg gcaaaagaaa
     8581 tccaaaaaat cgatcaacaa gatcctggta aagtttggtt gtctgaagat gaattatata
     8641 acttcacccc aacattggga gtgaaatcct tcaatacagt acgcttttat ccagatatag
     8701 ctgcatggaa gaaaatcgat ccgaaagaag aatacgagaa gtattataat cggtatgctc
     8761 atacaagagc ttttatcgct aaggaagata caaagttcat tttagatcgt ccagatatgt
     8821 tttcggtcac gttgaatttt gaagacgcag aaaaattagg gatcgactat gtgatcagta
     8881 aacgaccatt aactgattac aaccaattat atgaagcgca gttcacgcag ctatatggac
     8941 cggataaaga cggttatatg atttttaaag tagaatatcc ggattatcca gatgtaccac
     9001 aaacacaaac tcaggaaaat cagctagtcg tacagtaata ggctagctga gaataatcct
     9061 gaaatgttag tagaaaggag agtggagata attcaagcaa tcgtacaaaa atttgtcaac
     9121 aaaatgagtg tcggtttctt gcttttgtta ctgacgctag tcttttttgt ttggacagca
     9181 gggttaggtt ttccagcaac tttgtttata tataacaata gttcattact tatcgctttt
     9241 agtgtggcta ttttgctcat tttaaatgtt tataaagcaa aaggcgtcga ttttctttat
     9301 ctaggtgttg cgcttgccct tttcattttc ttttcttact ttcgggaatt aagaaatgag
     9361 tctttatttg gagacttact gtttcctttg attattttat tttgtttagt aattaaatgg
     9421 atcgagtgga caaaatggga tcgcggtatt tatctgattg tcttttcggt cttcctcgga
     9481 atcacgttat atcgtgtatt tacagagatc caagtaccag aaggacaaag catctgggct
     9541 ccaggcaatt cgctttctga tatttggatc aatacgaata taatcggaag ttctttgatg
     9601 actcttgctt tattgatcag tggatttgcc agttcttttg aacgatggta tgtacgaatc
     9661 atcggtgcag tagcagttgt tgcagctttt ctcgggattt gggtctgcca atctagaggt
     9721 gcattagtcg cgttgattgt ttttgcgata ttggatcttt tacctaaatc gttgatgcgt
     9781 gtcattcgtg cgccatttat tgcttacacg gttacgattc ttttagcttt gccgatttct
     9841 tatctggcgg ctgtctctga aaaagtcaat ttgtttaccg gtcgagaaga tatttggcat
     9901 aaattctatc agacgctagg agaaaaatct gaacaaattt tactaggaat gaaaacattt
     9961 atcttccaac gaggaaacca atttttagga aaccacaata gttataattc tattttgaat
    10021 atctatggat tgataggatt tgggattgct gctttgctgc ttatcctttt tattggtcgc
    10081 ttaacgttga aagcagattt atccaacggg cagatgactt ttatctgggc cttttttgcg
    10141 gtgatgatgc agtcatttat ggaggataca ttgacttcat acccatgggt tccgattatt
    10201 tatatcctgt tggctatggc cgttcatcga tatgatgaac cagaagttgc ggaggaattc
    10261 tatgttatgg aagaggcata tgacgatatg acttatgatg atacatctta tgaggaacaa
    10321 ccagatagcg ctcattcttc caggatccaa cgctatcatt gataggcaca aaatacgaga
    10381 gaggctgtga caaccgtcgc agcctttttt ggtttattgc aattgtctag catcttctgt
    10441 aaaatagaaa cgttagagaa aatcttgtat catagaaaat taagaaagaa ataagaacgc
    10501 agctcggtac caaaaatatg gtaaaatggc acttgactgt aattcactga aaatcgcttg
    10561 gaggaacaca aatgtttaaa gatttgtatt tatttatgaa ggacatttat cagaacagaa
    10621 aattattgct acagttttcg atcaatgact tcaaatcaag atatgcagga tcgtttttag
    10681 gaatcttatg ggcgtttatc aatccgctat ttactgtatt gatttattgg ctggtatttg
    10741 gtgttggact gaaagcacaa atgatcgatg caaaataccc atttatcgta tatttagtta
    10801 ccgggatgat tccctggttc ttcttctcag atgcatttgc atcaactacg gttgtttttc
    10861 gggaatatac ttatttagta aagaaagtcg tattcaatat tcgtatcttg cccacgacga
    10921 aaatcctatc caatctgtac acccacttat tcttcattct gattggcata gctgtcgcgc
    10981 ttataaatgg tatatatcct tcagcaatgt ctttacagct gatttattat ttattttgca
    11041 tgtgtgcttt cttgacagga ttgacttggc tgacggcatc gatccaacca tttttacctg
    11101 atatcatgca attaattacg atcgtgctgc agttgatcat gtggacatta ccgatattat
    11161 ggagccctaa tcagtttgat tcaggtcttg taagcatatt gaaattaaat ccgctgtact
    11221 atgttgttca aggttatcgt gagtcatttt taagtgaagc ttggttctgg gagcatggaa
    11281 catatacttt gtatttctgg gttttcacgt tagtaatgtt cgtaatcggc tctgcagtgt
    11341 tccgtagatt gaaaccacat ttttcagatg tgctgtaagg agaatagcta tgacagaata
    11401 tgcaattaga ctaaaagata tcacaaaatc ttataatatg tacgcaaaac cttcggatcg
    11461 atttcgtgaa gccctcaatc cttttaagaa atcctatcat gatgtatttt atgcgttgaa
    11521 aaacgtgaat gtagaaataa aaaaaggtga gatgatcggt ttcgtgggag aaaacggatc
    11581 gggaaaatct acaatgttga aaatcattac gggagtactg acaccaacat ccggcacgat
    11641 ggaaatcgaa ggaaaaatct cagctttgct agaactagga tcaggattca atcctgagta
    11701 ttctggctat gaaaatatct atttaaatgg aatggttcta ggattttcaa gagaagaagt
    11761 cgatgaaatg gtcgatgata tcattgaatt tgctgacatc ggagaccata tttatcaacc
    11821 tgtaaaaact tattcaagcg ggatgttcgt tcgtctagct tttgctgtag caatcaatgt
    11881 gaatcccgat attttgattg tggatgaagc attggcagta ggcgatcttg aatttcaact
    11941 aaaatgtatg gaaaaattta cagaaatcaa gaactcggga aagacgattt tattcgtttc
    12001 tcatgatatc agttcgattc gtcgtttttg tgatcgttcc tattggttga aaaacggaga
    12061 agtcgtcgaa tatggcgata cgatggaagt aacgacgaat tatgaaaact ttttaaagaa
    12121 aaaatcagtt aaaacagtgg atcggaataa aaaccaagta gaacggttcg ccgctccaga
    12181 tatcgtcgac gtgacgaaag cggaattgtt ggataaagac aaaaatccgg tggatatgct
    12241 ggaacaagga gaaaaactat acgttaaagt aacttatgaa gtaaaagatg atacaatcaa
    12301 aaatccggtt ttaggaattg cgctacgaac agtcgacaat ttttatgtat gcggacttaa
    12361 tactctacta gatggtatca agattccttg gaaaaaagga gagaatatct tttatctgga
    12421 gtatgaaaag ttaggtttgt tagctggtga atattatttt gacgttgcgg tctttgaaga
    12481 aaatgcaacg gttcctttgg tatataagac aaagtacatg aacttgtttg tcagcggttc
    12541 ttatatcgga gaaggcatcg tggtcttaga ccataaatgg gaagaaggga ctcatagcaa
    12601 tgaaatatga ttttgaaatg gacctagatg aacaaagcag tgtgggaaaa attgccgcac
    12661 agatcaaacc aggaagtaaa gttttagagt ttggtcccgg aaacggccga ttaacgaaac
    12721 atttaatcgg agcaaaacaa tgtgaagtga gcattgttga gttagataag gaattgttcg
    12781 attttgtcag cgaatttgct caagatggat tttatggtga tatcgaaagt tttgagtggg
    12841 caaactatta tgctggacag acatttgatt acgtcttgtt tgcggatgtt ttagaacatt
    12901 tggtagatcc tggaaaaaca ttgaagaaag tcagagaatt tttgaatgaa gaaggagaga
    12961 tcctgattac attccctaac ttggcgcata attctgtcat gatcgatttg ttcaataacc
    13021 aattgccgtg ggcttcttat ggtctcctag atgaaaccca taattctttt tatactcatg
    13081 atggcttcca aaaagttttt gaaaaagcgg gattattcat taatattgaa gattatttgt
    13141 acttagctgt aggtgataca gaattaaaat caacttatga agaattgccg gaagctgtac
    13201 gctatgattt caaaatgcga ccatttggtg aagtctacca atactttttc tcattgatga
    13261 aacatccagt agcacaaagt tccattgcag agccacaaaa ttctaattat gtaaaagtgt
    13321 tagaagtaac ccagcaaacg aaacaagatg aaacaatcca acaaatacca ttcaataatt
    13381 tcacagggga aaatgagaca ctaagtttcc ccgtatcaga aacaacagaa agaatggtgt
    13441 ttcgcttcgc gcaacaacct agctttatcg aattcagcgc agaagctgcc ggagaaaaac
    13501 taacatttat cgattcgaat gctgtagtca aaacagtaaa tgattgttat ttgtttgatg
    13561 ggaaagaatt accagagttc gttctaacgg atatttctgg gaaagaagtg actatccatt
    13621 gtcactatcg ctttatcggg gaattgacac caacaatgaa agaattgttg gaaacgattc
    13681 gtcccatggc tgaagtcaca aagcagcttt ctgagaaaaa tgacgaatta gaaagagaaa
    13741 atcatcatct tcttgaggaa aatacaagac tagaccatac gttaaaaaca accacaaatc
    13801 gctattgcac attgttggaa agtgatgaat ggacaataaa acatagacta ggacgacgta
    13861 agaaagaaac ttcgaaaaaa atccaagaaa aagaactttc tatatgtatt gacgagaaaa
    13921 tctgggatgc agaaacaaaa atattaaaaa tcatcggatg gggaatcgct aattcggatc
    13981 gccagccctt gtcctataag ttatcagctg accaatcgcc atttttcgaa gcaattcctg
    14041 tttcacgaga agaagtcaat caagcagaac agctcgcaaa aggaacagaa gcgggatttg
    14101 agttacgaat cctttgcgag caagaacgtt cattcttagt ggaagcagta gctcaaaatg
    14161 gccaatcatg gatcattgaa atgtaaataa tgattaactt ataaagataa ggagtaaacg
    14221 aatcgtgcaa aaaaaagaaa ttgccgtatt tatcgatcaa atcactcgtg aacgggccac
    14281 tggcgatttg cttattgtgg gctgggcaat tgatgaagtg accaaagaaa tccctacgat
    14341 aaaggtagaa aaagaaaatg tgattgctga agcaacacat gtcgtaagat tggatatcaa
    14401 tcatttatat aatcttgatg ttaagaccca aagcggtttt aaggtacgtt tatcagggaa
    14461 aatgagagga aaagccatct tagacttcca aacagcgaga catcaaaatg gcatagctgt
    14521 gaaattaaac ggtaaatacc cttatgatga cggcattgaa tcttcatggg aaagaaaaaa
    14581 aagattactg aaaaaaggga taaattatgc aaggactcat ggcgtaaaaa aagcgatccg
    14641 tcgggtcaaa ttggaattga agccaggatc gatcgactat gcagagtgga tcagtcgtca
    14701 tgagaaacca gatttgaaag agcaaaggaa agaagcacaa ggatttgcgt accgtccatt
    14761 gatttccata cttatgcctg tctataacgt tgaaatcaaa tggctcgaaa aatgcattga
    14821 ttcggtactg gatcaaacgt atgatcattg ggaactatgt atcagtgatg atgcttctac
    14881 tgatccagct atccgaaagt gtctggaatc ctatcaagca aaagatgata gaatcaaagt
    14941 cgttttccga aaagaaaatg gacacatcag tctggcaact aattctgcat tggaaatagc
    15001 agaaggagaa tttatagcac tcttagataa tgatgatgaa ttaccgccat ttgcattata
    15061 tgaagtggca aaagtgctaa acgtacatcc agaactggat gtgatctaca gtgacgaaga
    15121 taaaatcgat gcagatggca atcgctttga tccgcatttc aaagcagact ggtcgcctga
    15181 tacattgatg ggaaataatt atatctctca cttaggcgta tatcgaacaa gcattgttaa
    15241 agaacttggc ggtttccgta aaggctatga aggttctcaa gattatgatt tggtccttcg
    15301 tgtgacagaa caaatccctg cagatcatat ttaccacatt gaccgagtct tgtatcattg
    15361 gcggacgatc ccaggatcaa ctgcaagtaa tggcgaagcc aaaagttata tctatgattc
    15421 cggagtgaaa gcattgacag atgccctgtc tagaagaaac atcaaaggaa gcgtacgtcc
    15481 tggcagaatt tctggatttt atgagattgc ttatgacgtc ttgcaagagg atttggtcag
    15541 tgtgatcatt ccaacgaaga atggctatga agatctaaaa acttgtgtgg attcgatcat
    15601 cgaaaaaacg tcttattcaa attatgaaat cattattgcg gataacggaa gtacagatcc
    15661 aaaaatgcaa gaattatttg cagaatacaa gcatcagctg aaagaccgct ttatcgtaga
    15721 attgattgac attccattca attattctcg aattaacaat ttagcagcag aaaaagcaaa
    15781 cggcaaatac tttttattct tgaataacga tacagaagtg attgagccag attggatgac
    15841 ggtgatggtt tcttatgcac agtttgatcg aatcggctgt gtaggagcaa aactgtttta
    15901 tccagatgat acaacgcagc atgcaggagt attattagga atcggtggtg ttgcagggca
    15961 tgcattgaat aactatgatc gaacacattg tggttatttc ggccgattgg tcattgacgt
    16021 caattactta gcagtcactg cagcttgtat gatggtcaag gcagctgact tcaatgctgt
    16081 taacgggttt gatgaaacat tagaagtagc attcaacgat gttgacttgt gcttgaaagt
    16141 ttatgaactg ggtcgttaca atgtctatgc acatcaagca gaattgtacc atttcgaatc
    16201 taaatcaaga ggttatgaag atactccaga aaaacaaaga cgttttgctg gtgaaatcaa
    16261 aaaaatgcaa gataaatggc cagcatatat tgcgcatgat ccattttaca atgataattt
    16321 aacaaaagaa ggaatcggcg acttttcgtt gagaccagat taaactataa taaaaagctg
    16381 ttatgttgtg attcgctcgc acataacggc tttttatagt tttttgtcaa aaaaaggcag
    16441 aaggtgccga ctcaaaaaaa taagtcgagg ttgggacaga agtgtttaac tccgagaaat
    16501 aagaagaaat tcacgaaaat tgcttttcaa atttttgtga atttcggctt atttaagaag
    16561 aagttgcttc tgctcccacc gtttattcgt ttttaaagaa tgagacaaaa gtgtttctta
    16621 cttttgtccc acgctcttat tcatgctcag agcgccaata gatacaaaat catagccaaa
    16681 gtttcacgaa ccctagctgt caaagaatcg atattttatt ttaatatagg ctattttaaa
    16741 ataaatggtt taaggtattc ctctacaaaa gccactctat caattatcat gggtttaaaa
    16801 taagaagtga tggagataac cagattgttc ttagcgtcaa tataaagaac atttccacta
    16861 ttaccaattg ctgaatatat ttcgttctca gaatctaata cccaccataa atagccatat
    16921 ctcatatttt gtaagtcttc taaagcactg gttctaggtt tgaacatctc gtttatccac
    16981 atgggtggta cgatttgttt tcctttatac atccctttat ttaggcataa tacaccaatt
    17041 tttgccagat cacttgccga taaacacaaa ccatatcctg ccgtcccgat atttagtgga
    17101 tcacaaaacc agacattggt tttaggagac ttatccattg taaactgctt atgttcttca
    17161 gctgtttcag cataataatt gacatggttt ggtatcccta taggatcaaa tagatactta
    17221 ttggcaaaat caacagttgt tagcttactt gtctgataca acaagccagt taatatgtgt
    17281 aaacagacag tttgatagtt gaattcgccg gttatacctt ttcttcctcc caataaatct
    17341 agtgatgttt ttgtccaatc ttcacttgaa cagacttttg tccatggatc gcctttacat
    17401 ttgtagggtg ctttcattgt tagcaagtgc ttgattgtaa tagcgtaaat agttttctcc
    17461 ccgcgtttca ctttatactc tggaaaataa tctaatactt tatcatcgat acttttgatt
    17521 aatccttgct ctaaagcaat gccaatcagc aaagatacaa tacttttcgt tgctgacatg
    17581 atatgacaag tatcgtcttt tttataacca ttccattcat ctgtataaac ttctacccca
    17641 tccttatatg cgacaatttg acatatattt ggttgtcgaa aaccaataaa atcatgcaac
    17701 tcttgtttat tcataagata ttacctcact ttcttctata agcataatgt cattaaaaat
    17761 cgatttcaat tttttcgatt cttcacgtaa tacaggtatt cttatggact agacagcgct
    17821 ttgggaagat ggattctctg aaaaatataa aggttcactt tatgagtgga taaaaaaagc
    17881 agcaaatact tcgacttctt taatttacca acattagtga aaatcgattc atctggagat
    17941 ttgtaattta gagtccttgt cttgattaga ggtgtataaa gctttttatt agacattttt
    18001 aaattccatt acaatttgct tataaactag gtttttaaag gtgactatgg taagataata
    18061 gagatattat tttgtgatta ggagtgtata tatgaataaa aatggagaat ggagtgctgc
    18121 acgacggata ttcattatat taatggatgt tattgtatac aatgcagcaa tatatagtag
    18181 tttcttactg aagtttcgtg gagagatccc attacgaaat ttagaaactt tccaacactc
    18241 agcaattatt atttcagtga tttttattgc gttgaacatt ttgttgggtg catatgtttt
    18301 ttataatcga atgatcagtg acatcgtgtt tgtcacagtc atcggtcagg tattgatgac
    18361 actagggatc atggtagtga cttttgcggg ccgctggttt gcttttccac gtcttgttat
    18421 cttactttca tttgttctcg gtacgctttt cttaagtatc tatcgtattc tcgtatataa
    18481 actttattta cgcgtaagtc gagataaaaa ggtcgtcatt attgggttag aaaaggatgt
    18541 cgcaccagca atccaaaatt ttggttcaaa gaaaaacaac aaacataaag tcgaagcagt
    18601 cattcttgat aactattatg caaacatcaa aaatatgatt aaagacatcg atattgtcta
    18661 tcttgcttct catatcgaag aaactgaaaa aatcaaaatc tatcaattag ttactaaaaa
    18721 tgaaaaaaaa ttgtttttga atacaacatt tgaaaacttg acattgatca atccaaatat
    18781 tatgaatttc gaagatgaaa gtattattga agcatctgga tttagaatcc aacctgaata
    18841 tgaactattc aaacgtttgt ttgatatcat cgtttcactt gttttattag ttattgcttc
    18901 accatttatg ttattcacag caattttagt caaagtgaca tcaccgggac caatcatcta
    18961 taaacaagtg cggatcacaa aaaatcaaaa ggaattttca atctataaat tccgctcgat
    19021 gaccgccaca gccgaagcaa aatctggacc agttttagct aagagcaatg atgcacgagt
    19081 aacgcctgta ggtaaattta ttcgagctgt ccgctttgat gaattaccac aaatcttcaa
    19141 tgtgctgaaa ggcgatatgt cgatcgtagg accacgtcct gaacgtcctt tcttcgtcga
    19201 tcagttcaat gcagaaaacc cttattacta cttacggcat aatgttcgtg ctggtatcac
    19261 tgggtatgca caagtctatg gaaaatatgt ctctgattac aacagtaaat tacgttttga
    19321 tttactttat atcaaaaaat attcattgat gcttgattta aagatcttgc tgcaaaccat
    19381 caagatccta tttgataaaa tgtcctctca aggacttgaa gaagacgaaa atgtgatctc
    19441 attggcagaa attgcttttc cgaatgaaaa aatctttcgc tagttgggag gcgtaaaaat
    19501 gaacaatccg aaattcagca taatcgtacc agtatacaat gcagaagcaa ctattggtcg
    19561 aacgattgat attctaaaag aattggatta tgaagagtac gaagtcgttt tagtaaatga
    19621 tggatcaaca gatcaaacac aggaaatcat tcaagaactg attgaaaatg atgaacgttt
    19681 tgaattgatt actacgacca atcaagggcc cggattagca agaaacgaag gaataagaca
    19741 gtcaaaagga gaatatctct tattcttcga tgcagatgac acgccagtaa aaacgatctt
    19801 gtcagattat gatcatttgc tagaaaagag tccaaaagcg gatcttgttg ttagttcgtt
    19861 tgtttttcgt acaatggacg agggaagaat cgtttccgaa aaagaaaact tagttacaga
    19921 atgtcactat ctaactcacg aagagtttat aaaagacatg tatcagttaa tgaatgaaca
    19981 gttgatgtat gttgtatgga acaaatgcta tcgtagcgat attctgaaaa ataaccaaat
    20041 tctatttaaa acttataata gttgtgagga tcgaatattt aacttacatt attatgaata
    20101 ctgtcatcaa gtgatcatga acccaaaagt agaatatatt tatgaatttg aaggtgggaa
    20161 ggggatcact aatcaatacc gacctaacaa gttcgaaaca tttaaagaat tctattcatt
    20221 agcaaatact gtaacagacg atattaataa agacggtatg gcggcgcttc ttttaaaagg
    20281 gacaacttca gttatttttt ctatttatag tacctctgca agaacttcaa aagagaagaa
    20341 agacgaagca aagcagatat tgagtgatcc agtgatccga gaagccaagc aaattgctaa
    20401 gacggattct tcagcaaaaa aaataacaaa gttgctttac aatatgccag ctccactatt
    20461 tttatctgct gtaaaagttg gaagcttcgt tgaagtgaaa atgccagggt taatggctgc
    20521 tttgaagcga gtatattagt taatggagga aaatataatg aaaagaattt tgcattttca
    20581 gggacgaatg ggtttaggtg gagcagagtc tttcatgatg aatttatatc gtaaaattga
    20641 tcgtacaaac tatcaatttg attttttgat ttatgaagat tatgcagatg ttcaagacta
    20701 tcattcagag attgaaagat taggaggccg tatttttgtt g
//
LOCUS       DAZKCH010000050        20605 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000050 DAZKCH010000000
VERSION     DAZKCH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.050"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            109..303
                     /locus_tag="ACG84X_001807"
     CDS             109..303
                     /locus_tag="ACG84X_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127674.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            572..871
                     /locus_tag="ACG84X_001808"
     CDS             572..871
                     /locus_tag="ACG84X_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127675.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(968..1402)
                     /locus_tag="ACG84X_001809"
     CDS             complement(968..1402)
                     /locus_tag="ACG84X_001809"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9127676.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1634..2344)
                     /locus_tag="ACG84X_001810"
     CDS             complement(1634..2344)
                     /locus_tag="ACG84X_001810"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFP9127677.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2334..3194)
                     /locus_tag="ACG84X_001811"
     CDS             complement(2334..3194)
                     /locus_tag="ACG84X_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFP9127678.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3199..3837)
                     /locus_tag="ACG84X_001812"
     CDS             complement(3199..3837)
                     /locus_tag="ACG84X_001812"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFP9127679.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3852..4151)
                     /locus_tag="ACG84X_001813"
     CDS             complement(3852..4151)
                     /locus_tag="ACG84X_001813"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9127680.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4194..5678)
                     /locus_tag="ACG84X_001814"
     CDS             complement(4194..5678)
                     /locus_tag="ACG84X_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFP9127681.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGVLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5698..6159)
                     /locus_tag="ACG84X_001815"
     CDS             complement(5698..6159)
                     /locus_tag="ACG84X_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9127682.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6177..7244)
                     /gene="ulaG"
                     /locus_tag="ACG84X_001816"
     CDS             complement(6177..7244)
                     /gene="ulaG"
                     /locus_tag="ACG84X_001816"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFP9127683.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7462..8232
                     /locus_tag="ACG84X_001817"
     CDS             7462..8232
                     /locus_tag="ACG84X_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9127684.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8505..9332)
                     /locus_tag="ACG84X_001818"
     CDS             complement(8505..9332)
                     /locus_tag="ACG84X_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127685.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9900..11135
                     /locus_tag="ACG84X_001819"
     CDS             9900..11135
                     /locus_tag="ACG84X_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9127686.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12134..12394)
                     /locus_tag="ACG84X_001820"
     CDS             complement(12134..12394)
                     /locus_tag="ACG84X_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFP9127687.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12421..13722)
                     /locus_tag="ACG84X_001821"
     CDS             complement(12421..13722)
                     /locus_tag="ACG84X_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9127688.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14014..14472)
                     /locus_tag="ACG84X_001822"
     CDS             complement(14014..14472)
                     /locus_tag="ACG84X_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFP9127689.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14485..15816)
                     /locus_tag="ACG84X_001823"
     CDS             complement(14485..15816)
                     /locus_tag="ACG84X_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HFP9127690.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15827..17269)
                     /locus_tag="ACG84X_001824"
     CDS             complement(15827..17269)
                     /locus_tag="ACG84X_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9127691.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17256..18020)
                     /locus_tag="ACG84X_001825"
     CDS             complement(17256..18020)
                     /locus_tag="ACG84X_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFP9127692.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18124..18999)
                     /locus_tag="ACG84X_001826"
     CDS             complement(18124..18999)
                     /locus_tag="ACG84X_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFP9127693.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19254..19338)
                     /locus_tag="ACG84X_001827"
     tRNA            complement(19254..19338)
                     /locus_tag="ACG84X_001827"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19302..19304),aa:Leu,seq:caa)
     gene            complement(19356..19427)
                     /locus_tag="ACG84X_001828"
     tRNA            complement(19356..19427)
                     /locus_tag="ACG84X_001828"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19393..19395),aa:Gln,seq:ttg)
     gene            complement(19437..19509)
                     /locus_tag="ACG84X_001829"
     tRNA            complement(19437..19509)
                     /locus_tag="ACG84X_001829"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19474..19476),aa:His,seq:gtg)
     gene            complement(19571..19655)
                     /locus_tag="ACG84X_001830"
     tRNA            complement(19571..19655)
                     /locus_tag="ACG84X_001830"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19619..19621),aa:Leu,seq:caa)
     gene            complement(19676..19746)
                     /locus_tag="ACG84X_001831"
     tRNA            complement(19676..19746)
                     /locus_tag="ACG84X_001831"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19712..19714),aa:Cys,seq:gca)
     gene            complement(19792..19863)
                     /locus_tag="ACG84X_001832"
     tRNA            complement(19792..19863)
                     /locus_tag="ACG84X_001832"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19829..19831),aa:Gln,seq:ttg)
     gene            complement(19875..19947)
                     /locus_tag="ACG84X_001833"
     tRNA            complement(19875..19947)
                     /locus_tag="ACG84X_001833"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19912..19914),aa:His,seq:gtg)
     gene            complement(19950..20023)
                     /locus_tag="ACG84X_001834"
     tRNA            complement(19950..20023)
                     /locus_tag="ACG84X_001834"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19989..19991),aa:Trp,seq:cca)
     gene            complement(20030..20110)
                     /locus_tag="ACG84X_001835"
     tRNA            complement(20030..20110)
                     /locus_tag="ACG84X_001835"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20074..20076),aa:Tyr,seq:gta)
     gene            complement(20112..20187)
                     /locus_tag="ACG84X_001836"
     tRNA            complement(20112..20187)
                     /locus_tag="ACG84X_001836"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20152..20154),aa:Phe,seq:gaa)
     gene            complement(20223..20295)
                     /locus_tag="ACG84X_001837"
     tRNA            complement(20223..20295)
                     /locus_tag="ACG84X_001837"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20260..20262),aa:Asp,seq:gtc)
     gene            complement(20305..20377)
                     /locus_tag="ACG84X_001838"
     tRNA            complement(20305..20377)
                     /locus_tag="ACG84X_001838"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20342..20344),aa:Val,seq:tac)
     gene            complement(20393..20464)
                     /locus_tag="ACG84X_001839"
     tRNA            complement(20393..20464)
                     /locus_tag="ACG84X_001839"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20429..20431),aa:Glu,seq:ttc)
     gene            complement(20479..20568)
                     /locus_tag="ACG84X_001840"
     tRNA            complement(20479..20568)
                     /locus_tag="ACG84X_001840"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20532..20534),aa:Ser,seq:gga)
BASE COUNT         6506 a         4315 c         3267 g         6517 t
ORIGIN      
        1 actttcaaat tgattctttt tatttatcat aaagatatag atacataatc attttcactt
       61 acatatattt gaatattaac taaaaacagc aagaaagaag aggatcaaat gtattatgta
      121 gaagtaaaaa caaaaggcgt caaaaacaaa caatatgtga aaggtatcag taacgaatat
      181 cctttacttg gttcatggaa agaagctgct cctttttcca aaccatgtgc cataaaaata
      241 aagaacgagc tagaaaaaga actgacttgt ggtaaagctg ttgtagatat catcgaaaag
      301 taaatccaat gtatagaaag gaagatcaca catgaaaagc gacgtacaaa ttgctaagat
      361 tatagaatta gaagaagaag acgcagtgtt gacaattgaa aaaaaataaa tgtttgtata
      421 ccatatgatt atttcaatat gtatcctgga attggagatc tcgtagagct atatcaagat
      481 gaatcaaata tacttgtcat tcatcatgaa atatagagac ttataaaatt gtttattttt
      541 ataatgtatc agtatagaaa ggaaataaaa catggattat actgttgaat ttgacagtga
      601 actacttaag caatttccac aagaagaaca tttcatgtat aaagaagcaa tttcccacaa
      661 agtgacagag tatttggagc ataatttttt tcgtataaag ccagtgcgta ctcgttcggc
      721 aaaaggaata tacgagatga aagtcaaaat taataaaaaa aattatcgca tagcatttgc
      781 tttaaaaaaa aatcatgtgt tcatttttta tattagttcg aatttgcaaa aaattgtatt
      841 tgataaagag gtgagtaaaa aaataaaata gctgagcatt ggaggataga ttgagtgata
      901 ctaagtctat cctcttgttt ttctaaagaa ctaagctaga attttttctt ttgtacgtta
      961 ttatatgtta tttgtcatta ccaaaaagca ccttttttct tctagtatct atgacataag
     1021 aaataccacc catttccttt acttgaacaa atcctactga ttcataaaat ttttttgttt
     1081 tctcagtatc atctgtcaat aattcgattt ggactggtcc ataactagtg atcttctcca
     1141 aagcttcatt caaaagcact ttgcctattc cttggcgctg atacctcgga tgaatgagga
     1201 tatcttgaat aaatgcgatc gtcgcaaaat cagtgatcca acgaacgatt ccgataatct
     1261 tcccttcccc attacgcttt atcagagatt cagattgttc aaatgctcta gctaaccttg
     1321 cagtgtcttt tgtgtaattc gtccaaccaa cgctcttata taattcagaa atctcatcga
     1381 tcataaggga atcaatattc atttttttct tcctttctta tacaattctc cctctaataa
     1441 tacagttctt tgactattta atctatcaca tataactctc ctgtaaagat tctctcgatt
     1501 ccttaaaatt cctctttcct tttagaatgc atactttttg ataaataaaa aggttgtgat
     1561 aaattttctt cacaacctct gtttctctct atcaagtgtt atcttttaat tttctaccct
     1621 taccctagca tctctattgc ccgtagtatg catactttcc atgtttgcga aaataatgtt
     1681 tatctagtaa atattgcggg atttcacata tattggggtt gatcagctcg ttttctttgg
     1741 ccatcagaca aatttcatct aagatcaaac tgttttctac tgctttcata ggtgaatccc
     1801 cccatgtgaa cggtccatgt ccatagacaa gtactccagg gacttcgttt ggatctaatt
     1861 ttctttcctt aaacgtctcg acaatcacat tccctgtatg aacttcgtaa gcttctctta
     1921 cttcttcttt cgttaattgg cgtgtacaag gaaccttacc ataaaaagca tcagcatgag
     1981 tcgtgccata agctggcaaa tcgcgtcctg cttgcgccca catgacggag tgcgtggaat
     2041 gagtatgagt aatagcagtt atatcttcaa aagtttgata caaaacaaca tgtgtgggga
     2101 gatctgaaga tggttttaag ctatcttctt ctattatatt tcccgacaaa tctgttacca
     2161 ccatttgatc tgcttgcatg cattcatatc tgacaccgct tggcttaatg acgatgactc
     2221 ctagctcacg gtccacttca ctcacattgc cccaagtcaa tttgactaat ccgtatcgcg
     2281 gcaatgccag atttgcttca aggacacgtt gcttcattgc tgcaattttt tcttcacaag
     2341 acatcatagc cagcctcctt caatttagaa cttaagtagt cttttgcctg ctggatttct
     2401 cttcgaaagt cttggctttt ttcactccac atttcaatca gaaatgttcc atcataatct
     2461 agacgtttca aatgtcttaa taatccaaga aaatcaacac aaccgctacc aaaaggaaca
     2521 tcacgaaact ggcctgaata ttcttttgtt acagggtaag tatcttttaa gtggatagca
     2581 gtgatataat cgatcccttt ctcaagttct cgagccggat tattttccgg ccatgcggac
     2641 aaattgccta ggtctggata tacttgtaga aaaggtgaat gaatctgttc tttgatttct
     2701 aaaaattttg aaatggagtt cataaatgga tcatccatga tttccacgga aagaatgatg
     2761 ccatatttag aagcttcctt tacgctttct tttattcctt cgataaagtc ttctctggaa
     2821 ttcattgatt tctcttcata ataaacatcg tatccagcta tttggattac tttgacgctt
     2881 agattatgcg ccaaatggat tgcttttttc attagttgtt tcgctgcttt tttcttttct
     2941 ggatcagcag aaccaaacgg aaatcgccga tgcgcactta aacaaatcga atggatacgt
     3001 acaccggagc tgaacatctc ttctctcagc tcagctatct tttcttcaga ccaatctaat
     3061 cgtgctaacc gctcatccgt ctcatcaatc gacatctcga taaaatcgaa gtccatttct
     3121 tttacaaggg aaaaacgttc tttccatgaa atatctttgg gtaacgcttt ttcataaatc
     3181 ccaatttgag ccatttcctt acccccagat acgaatgatc tcatctttga agttttgtgc
     3241 ggccttcatc ggatcatttg ctgctgtaat accacgacca gtgataaagg tatacacatc
     3301 gatcccttca aataagtgta atgtgtgtgg atttaatcca ccagttacag aaacattaaa
     3361 gcctagttca atcagttttt tgatcttcga taaatctttt tcaccccaag tttcaccaga
     3421 taacagcgca tcacggcttt gatggtagat tacctgccgg ataccgatgt tatgccaatc
     3481 catggcttgt tcaaaagtcc aattgccgta gagttctact tgcaattcac ctatttcttt
     3541 ttgtgctgcc tccatagttg gaatcgttgc acaacaaatg actgtcatcc agtctgctcc
     3601 tgcttttgca acattactcg ccactgttcc tccagcgtct gcacatttcg tatcagcgac
     3661 tagtttttta tctgggaaca tactgcgaat acagcgaatc gctttttgtc cttcctgtaa
     3721 gcaaagaatt gtgcccactt caataatatc tactacatca ccaactttca taacatctcc
     3781 taatgcatgt tctaagtcat tgtgatctaa cgcaatttgc aaattcggcc tgctcatctt
     3841 agttccttcc tttacttgtt tttttggtac cactttgttt cagcaaattt ttcactgatt
     3901 tctttgactg acatcacatt tttgataccg ataactgtaa ctcctttttt ctctgcctga
     3961 gtaaacatat tcaaaaaatt gactggcgta aaaactacat cgtattggcc agctgaactt
     4021 tttccctctg aaatggcaca atgatggatt ttggtaattg gtacgtttag ttctttcatt
     4081 gctttttcca cacttctcat catcatcaag cttgttcctg atccatttgc acacgatact
     4141 aaaattctca tcttaatccc tccattatga gtgttgtcta atcagatttt cttttatact
     4201 ctctgctttt ctgcatatgt gtcatagtct tctacaatca aaaaataacc atcaggattt
     4261 ttccgatatt gtaactgcgg aatagccaat aaaccaatga caactacggc aattccagca
     4321 taacctagga ctttcatgat tactgtaaac aatggccaag ctgttgccca gtcgaacatc
     4381 ccgatataac caccgtatgt tgacatccca atccatgtag cgaataatgc tgaaccgcct
     4441 acttgtatga ttcctgaaag aaacgggaac aggcaagcgg ctttgaatcc acctcggtta
     4501 ttggcataaa ctgctataac ggcattatca aagaacaacg gaatgaaacc ggctatgacg
     4561 atcgttggtg atttcaataa aatcagtaaa ccaatcatca aaaactgtcc caaagcacca
     4621 aacaagaccc caatcgttac cgcatttggc gaaccaaagc caaaagtagc agctacgtca
     4681 attcctggaa cagctcctgg taaaatcgtg tttgagattc cttggaaaga ttgagttagt
     4741 tcatcgacga atgtccgaac acctaattgc aagatcgcca gatataccgc aaaatttaaa
     4801 gaagtcgtca taatgtagaa taagaaactc tgcccttctt gcatgaattg cgcttgaatc
     4861 aaataatctt tgcctagtac aatcagaatg atcccaaaga aaaatagcat gagtaacgaa
     4921 gtagcaacca tattctcatt gaaaatcgac aagaatcctg gtaatttgat atcttcaatt
     4981 tttttgtctt gcttgattga tctatttttc ttttcatccc gctttttcat ccactcagct
     5041 aattttgcaa atataaagat tccgaacatt tgctgatgtg ccactgcaaa tccggcacct
     5101 tctgtcaatt cctgcgtgat tcctactgtt aagttagaag ctactgtcca ataacaacct
     5161 aaaatcagtc ccataaaaat caatgcttgt atcctaccta gatcaggaaa gcaaaacagt
     5221 aaaatccaaa aagcggtagc tgcttgttga acctgaacgt ttccggtagt gaaaacggaa
     5281 cgcagtttcg tatatttctg aaaacggact aataagatat ttaaaacaaa tgcaatcagt
     5341 aataaaatca tcacatctcc aaaggtacgg ccaaatgtct ccattaatcc agcatccaca
     5401 gcattttgtc caaaataagg atctgtaacc atggcatcca aattgaaccg ttcctttagt
     5461 ccaaccaaga ttggccgaaa attattgacc aaaccaccag agccaacagt caaaataaag
     5521 taaccgaccg ttgcctttaa gaatccagcg atgcattcat gaagcgggcg tttcagcaaa
     5581 atatagccta ataacacgat aaaaccaatc aggtatgctg gctgcgtcaa gatatttgtt
     5641 gcaaaatacg tccaaatgct taacaaaaat tcccccatct tttttctcct ctatcaatta
     5701 attatattct gccatcacaa cttggtaatc atcgatggag ttcgtagaga tgagacgctc
     5761 aaccaatcca tctgtcatta ataattcgga taatttttgg atattttcta gatgttcttc
     5821 tggatctttt gctgcgagtg taaaaaacaa actagccgtt ttctcctcat tctccccttc
     5881 actttcaaaa cggattggct gtttcaactt ggtaaatgaa atagctgttc caaaaacacc
     5941 atcacttttt tctgaagaat gcggcattgc tacttgaggt gcgatcacaa tataaggacc
     6001 gtatttttct acacaatgga tgatctcctc cacatacgtt tcatcaataa tttccttatc
     6061 gatcaataca agacagcttt cggcgatagc ttcacgccaa tccgtgattt ctttatctgg
     6121 gtaatgaatc aattgatggt caaaaaagta tttcagcaag aaactcccct tctttcttat
     6181 aaaaacgacg gaaacggtgt atcattttca atcgagaaga catcttcaaa tcctcgataa
     6241 aaattaaact caagatcatc tttgtttgtc ggatagatga atttcccgcc tacttgccag
     6301 atataaggtt taaatccata cttcaggcga tcctttttga atttccaaat ttcagtgatc
     6361 tcttttggat cagccataaa attagaccaa atatcgtagt ggacaggaat cactactttt
     6421 gcattcaatg actccgccat gcgcagcata tcaacagaag taactttgtc tgttatccct
     6481 cgtgggtttt caccataggc ccctaaacag acatcgattt tgtgttcatt accatgtttg
     6541 gcaaataaat tggagtaatg tgaatctcct gcatgataaa gattccctcc tgatgtttcg
     6601 aataaatagt ttactgcaat ttgatccatc tcctgaggca tttttccttt taatacctct
     6661 tctggatctt cacaagtgac caacgctgtc cgatcaaacg cttctaaagc tactacattg
     6721 atgtctttga ttttgactgc atcacctggc tttactgtaa tcgttttttc ttcaggaatt
     6781 ccccattttt gccacgtgcg aaccacttct tttggcccaa tgaatgttgc ttcaggacaa
     6841 ttttgatgaa ctgctgcggc tgtatggata tctagatgat cggaatggat atgtgtaacg
     6901 attaaagcgt ctacattttt tatcgcaaaa ggatcgatta cgaaaggctg agtacgtaaa
     6961 ttaggctgca tattttgaac gccactcata cgcatcatct gatggccttt tttcatcatg
     7021 ccattcccat gactacgttt tcccgtccca caccatagat cacataaaat attcgttcct
     7081 tcatgacttt tcagccaaat tcccgtacag cccagccacc acatagcaaa agttccagga
     7141 tccactactt ctgtttcgat ttcttcattc aagtatgtgc cccactcagg aaatgtttct
     7201 actaaccact tttcttttgt tacttcattg acagttttac tcatttgctt gctcccccca
     7261 tatcgttgtt ccaacttaca agtaaatatt aatgtgtatc agcatccatg aaaacccttt
     7321 tatatgaccg tttgtttttt atatgatttt ctttcagtaa tcaatgattg tttcagtata
     7381 ataaagacag atatgaatgt ttaaatgaac aactagtcaa ataaatccat ggatcaagat
     7441 gtccctcagg aggcaaaagt catgaaaaac tcacttgtca atattgaaaa acgtcaaaaa
     7501 gaaattttgg aactgcttca gcagactgaa caactatcaa ctttcgaatt agctgaatcc
     7561 cttgatgtat ctattagtac gatacgaaga gatttaaatt tattagaaga aaaaaacgag
     7621 atcatacgca attacggtta ttgttcttat aattacaaaa accagactga ttttgatcaa
     7681 tctggtcctg aaaggattaa acaagcgatt gccagagaag ctagtaaata cattaacgat
     7741 tatgatacgc tgtttatcaa ttctagctcg actgcgttga aaacactgga ttttcttcaa
     7801 tctaaccatt tgacagtcat tacaaacaac gtgaaaatca attactctcc gcacaaagat
     7861 aattgtagtt atattttaac tggtggagag atgcgctttc caaaagaagc actagtgggc
     7921 gacatcgcat taaatacgat ttcttcagtc aatgcagaca tttgtatcat tggctgtagc
     7981 ggagtcgatg tagtacatgg ggtcacaaca aagatattaa atgaatcaac gatcaacgaa
     8041 atgatggtca acaagacaat caaatgtaag attttagtcg ctgatcatcg aaaaatcgga
     8101 ctgacatcaa agttcaagat tgctgatatt tcagtctttg attatttgat cactgataaa
     8161 ttttgttctg aaaaagtatt agaggagatc agaaatacgg ggataaaaac cattcaagta
     8221 gattcatttt aagaaccagg acgtaaatat gtaaatagga ttatcaaaaa aatgaataac
     8281 aaatttatcg ataaatgaaa aacacgctac gctcaaattg ataaaggaat cccaagatgt
     8341 atccatccaa tcgataccat cataatctat tgcttctttt ataaccgtta tatgttgcct
     8401 aaataggaat caaacaatat cgaaaaaagg aggtatgaca aaagtcacac ctcctttttt
     8461 cgaataaacg gtattcaaat cagaacactg atttcacaac cactttattt caggtcgttt
     8521 tcaatcacct ttaccgcgta atcatttccg ttgaaacgcg ctattttttt tgcgtccata
     8581 tatctttcta aataatcatc ttctcctaat tgcttatggc aagaagcaat ttcataaagc
     8641 aagtattcca atgcataagt cgatttatgt ttcttattat actcaatacc cttctcacat
     8701 aattggattg ctttatcata atcctcgatt ttacggtaat aggtggcgat atcataatat
     8761 acaatgcaga ccatcagatt atcaaaatca gtctcactca atattttaag tgtacgctcc
     8821 acataaactt tcgcaaaatc taattctcct tttgacaagt agatcattgc cacgtttgca
     8881 gctgcttgta agtgatggat atctgtttcg gtcgtttgtt ccaacacttg attaaaataa
     8941 aataatgctg catctggttt tttcgcataa agatgatcaa gcagtccttg ataaaataaa
     9001 atttgattta aaagatcaga attacttact ttttcctgat cgatcgtttg taaaatttta
     9061 taagattctt ggtattttga tacagaattc aatgattgaa tctcatttat ttttttcctg
     9121 attttgtctt cttctgtttc tactaatata tcggagatct cgacattcag ctttttgcaa
     9181 agcgcactta agatattgat gcctggcgac atattcttgt tttcgatatt gctgacagtt
     9241 gcttgttcac aaatgccttc tgctaattgt acttgtgtta accccttttt ctttcggtat
     9301 tcttttagta atgctccatc tactttaatc aaaacaattt ccttcccttt aaaaaattat
     9361 ttctccttta tatcatacac aaaaaaaagt tctaaacaac caaaaatgtt tagaacagaa
     9421 taaaaatttt aattttaaaa taatattcaa attaaacaac tggcgtatct gctccttgat
     9481 ttctttttgt gttatctgaa taattatcgt ttacagttat aacacatagt gaaaattgtc
     9541 atggcgagaa agtctaagaa tatttttaaa cataactatt tctttcttac gtgtgtataa
     9601 tgacgacagc acacctatca attaatataa ttattttatt tttttatgtt ctcatgttta
     9661 tttttaatga cacaacttct cgtatttatc tggcacaaca tataaatcga tcaaaaaatt
     9721 gttgcgtgtt tttttgaaaa ttggagtttc aacttgatta caaaatttaa atttagaagt
     9781 tgtgaaaaca gcgagagaca gtttaatatt caaaatatac ataggctact cgaacgctgt
     9841 gttttttagt atactagtaa gaaacgaagg gatagactca ttccaataag gaggatttca
     9901 tgaagacaat tctttttgct cctgcagtat tcaatttagc tgagacaaca cgaatgattg
     9961 aggttgccaa agctatgaaa gaccgttatt actgtgtatt ctttggcttt tctaaaactt
    10021 ttgctccttt gatcacagaa agtggctttg agtatcattt actagcgccg atccttacga
    10081 aaaaacaaga agaacaaatc ataaaatttg accagttgcg tacacttaaa aaccctttta
    10141 ccaaagaaat ggttgcctct cgtatcacta gtgaacagag tctgattgct aagtttgagc
    10201 ctcgactgat tgtgacaggt tcgaatgtga caattttttt atcggcccgc aataaaaaga
    10261 ttcctttagt atatgttaaa ccctatgctt tgagtgaacc tttttttcaa tcagagcatg
    10321 cgctgatgcc ccacgagtta cgtttcttcg gccctttaag caatcccctt tggcactgga
    10381 caaaaaagcg tatagtaaat acccgatgga tccccaatgc cttcaaacac gctgcacaaa
    10441 aagaaatgct tcctttacca aaaacaagtt tacaaatgat ggatgctgat ctaaatctca
    10501 tcacaacgcc taaactattt ttggaagaag aacagctgcc ggaaaattat cgaatcgttg
    10561 gtccaatttt tgctaagctc agtacttcct tgcctgaaga agtgctaact tttatacagc
    10621 gaaagcaaca agaaagaaaa cgtattatct atttcgcaat gggtagttca ggcaatccgc
    10681 gtatgttacg caaaattttg ttcttcttac aaaaacaacc ggatctagcg gttattgcac
    10741 ctattgacta tctgcttgat gacattcaat ctgactcaga agatctttta ataacagaat
    10801 atctgtctag tcatcttttg catgaattca ttgatttttc ttttatccac ggcggggaag
    10861 ggaccgtcca aactgcctgt gaatccggca aaccgtttat cggtgtgggg atgcaatttg
    10921 agcaaagctg taatattgac tattgtgtaa aatacggaaa cgcaatcgcc ctcacaaaac
    10981 cagtgactga aagaaaactg cagattgctc tgcgcgaagt ttcttcaccc aagattcgtc
    11041 agcaggcacg cacgctgcaa gccgtttttc caataaatgg tccacaacaa gcaattcaag
    11101 aaatcgaaac cttcctgagc aaccacccaa tatagtttca agtagaaaaa gcttttttaa
    11161 tagagactca tcagtaattt cgctattcga gacccagaca gtgaaaatac aaaaaaagta
    11221 aatagtggat tgaaaagtta gagttactta aattacggtg tctaaaaaac acaaaatcat
    11281 ccttaaaata aaagatctga cgctatccaa atgagcatag gtagcgtctg ccatttattc
    11341 ttagtcaaat tctttgacac ctttctctgg ttggatcatc tcaacgtttc ttcaaaagaa
    11401 agaccataat aattaggcaa atacattttc ttaaaatgtg tcatatagat ctagaagcat
    11461 cgctttgtag agatttgtgc cgctagtccc ctcaacaatt actaaatcaa atgtaggatt
    11521 taccacttta tctttgataa tcaacctccc tcttctgttg agacaatgat ctcgcaatcc
    11581 gatgcatact cctatataaa ctgccagcaa tccccacata ttgagtagat catgtcagaa
    11641 tgttctatgt cgtcagcaac gatacactaa aagtcacgtt caccatgact gattgctatt
    11701 cccagcacaa ttatttctat acacgtttca tgatttgaat aaacactcac atcatacata
    11761 ttaccattca tacaccatac tgcagcccct actatatggt tgtaagctcc caaatctata
    11821 tttgacttga tcactttggt agtagatcta ctaattctaa atccattgct gataaaattt
    11881 ccattttttc ctccttcttt ctgccaaaac agttaaaaca ataataatct ttatgtaaaa
    11941 aagggctgtg acaaaagcct tgtcacagtc ccatattccg aataaacggt ggtcaaaagc
    12001 ttgcatctgc ggtaataagt tcaaccaaac gaaaaataag ccaacatttc acaaaaattt
    12061 aagaagcaat tttcgtaaat ttcttcttat ttcttgaagc taaccacttc tgttacaacc
    12121 acttttagaa catttaaagc ttcgatgtga caaaccatct atgctgctcg atcataaaat
    12181 tgatagcaaa aattccacaa agtacatatg tcccccatga aaacaaaaca ttcatatgcg
    12241 gtacaatgat ctttggaaga atcacgatca aaaatgatgc cagtgcccaa atccatcgat
    12301 tgatttgaat atgatatgta gctagcatat tcaatataag gtgactagcc gttaataaaa
    12361 agataaaaac aaaaaataaa atcagccaat acattgtttc ccaccttcta aaaaccaaac
    12421 ttagacagtc tggacttcgt tttctccacg actttgttca tctgacagca tctttttatc
    12481 ataagctttt acaaatggat aatagataat aaatgctatc aatgtgttga tcatgatcaa
    12541 gataacaaca cgccagtcat ttcctgctga aagataaccg ccgattggag ctggtaatgt
    12601 ccatgttggc aaaacagtaa atctattgac catttctaat ttgactgcaa aataactgat
    12661 aatagtcaaa actaaaggaa ctaagttgaa cgggatgaac atgtaaggat tcaacatcat
    12721 aggagctcca aaaattatgg gctcattgat attgaagata ccaggaataa tagaaaaacg
    12781 accaacctct ttcaagaatt ttgatttaca gaagaatata aacaaaacag ataccacgat
    12841 cgttgctcct gcaccaccaa ttgttaccgt ccattgataa aactgttcag gagcgatata
    12901 gggtaattgg gtggcagctg taccatctgc caatgccttt gcattctcat ccaacatgat
    12961 cagccacatt ggacgaacaa cagcccctac aatactcatg ccatggatac caaatgacca
    13021 caacaaatgg atcaaaaaca ttggtagtaa aacaccaagc aaattattcc ctaaaatatt
    13081 ggttaaaggc tcgaataacg ataataaggc agcgtttaca tcaaagcccg cgacgcttcg
    13141 aatcagccaa gtaattgtta aaatgactgc acctggaatc aatgcctcaa aactacgggc
    13201 aacagcaggt ggcacttgtt ctggcatttt gatagtaata tttcgatttt taaagaaacg
    13261 atatacttcc actgcaaaaa tcatagataa gatccccgca aacatcccag atgctcccaa
    13321 agaactcata ggtaagaccc agccaagagg tgcctcttca ggagttaaaa cgtttacagg
    13381 aacttgtaac ataaagaacg ttcctaaaga taatatacca cctgtcacac tatctaatcc
    13441 atatgattta gctagatccg aacccataac aaaagttgca taaatagcca tcaatcccat
    13501 cgtcatccta aagggtaaaa caatcgttgc cgaataaggg gcaataaatt cattccatcc
    13561 aggaaacggt aaattgataa agaccataaa aaatgtccca atcaaaatca atgacaatgt
    13621 tgaaacaacc ccattacgaa ttgctaataa atgacgctgt gtaccaattt ttgccattgg
    13681 tgggacaagt ttctcttcga cccatttcat cagcttttcc actaaaacca ctccttttca
    13741 ataaaatatg aaccattcat tgcatgacaa cgcaaagaat gttcataact aattatataa
    13801 ttaagaaatt ttatttcaat atattctctt aaataatcaa atttattttt aagaatcctg
    13861 aaaataagtt ttctaaatca taggagcaac aaaaaaattc gataattaac aaaaatcaaa
    13921 atgattaaat ctagtgattg aaacatatca tttcaaaaaa attttgtaaa ttcacccata
    13981 aatatcaccc tatttaactt ttttcatcgt acactaaaat tcaaaacaac tatctttaat
    14041 ctttacttct tggttttgtt ttaataaatt tccttcaaaa atgcctggag aaactacaat
    14101 gatcaccgta tctttttgtg cttgctccaa cttcttcaaa tctataatag ctaacagtgt
    14161 cccttctttt acctcctggt tactttcaac ccgtatctga aacggacttc cttcgagttc
    14221 aactgtatct aaacccatat ggatcagtat ttttctgcca gattcacttt cgatcgttat
    14281 ggcatgtcgg gtaggaaata tattatcgat tattccttta actggcgcat ggatatatcc
    14341 atcatgattc gttatagcgt atccaactcc tatcattttt gaagaaaaga cctcgtcttt
    14401 tactgctgtt aatggaataa tttgaccact agctacagct tttagaatgt ttcttgtttt
    14461 aaagaaatgc actttttatc acctctactt taatgctggc caatattttt tgtttacttt
    14521 gatcatttca tctagtattt tttttgcgac tctggcattt ggtacggttt gattcaatgt
    14581 aaatgcttgt aaagcttttt gataagaacc ttcaaagtaa gcatctacta gtaacttctc
    14641 tactgcaact tgtgcctcca tcaatccttt atgaaaatca ctgattggtt ttcttagtgt
    14701 aattggctcc acaccagttg caccaacata tgccggtatt tcaacaactg catctgaccg
    14761 tagattcgga atcgcccctt gattaggaac gattagcata aagcgacgac gatcatcatt
    14821 caacaaggaa atagctatat cgacgatata ttgtccatgc tccccaaaat taaagttcaa
    14881 tacttcttcc acaataccgc ggcgtatttt atcagccatt tctttggtat ttttctctcg
    14941 tccatccatg accatattag cacgtgtata ctctttgtca gtatgctcaa cgaccatatc
    15001 aggatataag taatactcta agtaattatt cgggatatta cttggaaaat ttttcgtgat
    15061 gactgacatc atttgaaagg ttttttgcca agttttatct cctatattaa aatcggcgac
    15121 ttgcatttct tttgttatta gtttttcaat aatctctggc ataatttctc gttgcaattc
    15181 tttatcataa atcgatgtat accagccaaa gtggtttaaa ccataatacg taacgatcca
    15241 attcttacga tcataaccgt aattcactgc aatcgtttct tcaattgaaa tagtcatatc
    15301 acaggcatta atcattttta cattcggata tttacgacga acagcttcag aaacgatcga
    15361 ctctggattt gtataattca aaatccatgc tttgggggca tagtcttgta tatgatcgac
    15421 aatttccaat aaacctttga ttgagcgcat cccataagca aatcctccga gtccacacgt
    15481 ttcttgtcct actaatccat gtttaagtgg aatcttttcg tccttttctc gcatctccaa
    15541 tcctccaaca cgaatttgtg agaaaacaaa atcgcatcct gtaaaagcaa gctttggatc
    15601 atccgttgca cgaatgcgaa tatttgaaaa accttttctt ttcagcataa atttaacaat
    15661 caagtacata tccatatttc tttcttcatc aatatcatat aaacgtattt cagataatgg
    15721 caaccgtttt tcattgttca aaatggcttg aacgattcct ggtgtatacg tactcccgcc
    15781 tccagctata gtgataatct gttttttcat catcatcttt tcctttctat tcttctaata
    15841 atttattgaa ttctgccata acataagtca cttctaagcc gatgataatt tgataatttt
    15901 tttcagttgg tttaatgatc ccgcttatcc ctaattgctt gattcgctgt tcctcgacca
    15961 tggtgggatc cactacctct acccgtaggc gtgtattaca actatagaca tccaggatat
    16021 tggcttttcc tccaaacgct tgtagcattt ttgttgccat atattcataa tttttacttg
    16081 ctaaccctaa ctctgtttct tctaaggtta cttcattgcc aaactctgcc ttagcttcac
    16141 gtcctaatgt ctgaatgttt ctcttattga tcaaataata aaaagtaacg taatacaaag
    16201 caaaaaagaa aattccgatt ggaagaatca aaatagcatt ggtagcgatt cgaaaattga
    16261 tgagataatc aacaatacat gctccgaatg taaaaccaat tcgtatattg aataagtaac
    16321 agacaatccc tgctaaaccg gcaaaaagtg catggatcac gtacaacata ggagaaagaa
    16381 acatgaaact aaattcaaca ggctcagtga tatttgcaat aaatgaagtt cctgcaccgc
    16441 ttcccatgat tcctttgacc atctctttat tttctttata agctgcttta tagatagcta
    16501 gacatatagc tggtatacca aacatcatta ctacaaaaaa aactgataaa aacagtccag
    16561 cctgaggatc tccgttgata aagcgtgtca tctctcctct gaaaacttcc ttgctaggag
    16621 atgtatagct tcctaaatcg taataaatat acgtattcaa cacatggtgc agtccaaagg
    16681 ggatcagcaa acgattcaaa aacataaata tccccacacc taatgctccc atatcaacga
    16741 gcagttttgc aaaattatca atcccaattt ggatgagcgg ccagataaag cccaaaaaaa
    16801 cagctgcgat tgtttgtaga atcatcacca tagtcaatgg gaatttttcg cccgcaaaat
    16861 aagaaaaaac tactggtaat ttttgttctt taaagcgatt atacgtccat gccgctacta
    16921 aaccggaaat aattccacca aaaatcccca tattcacttc tgggtccata atttctaagc
    16981 cttttttcaa ggtagcaatc gctaaaaaac cagtaagtgc aggtattcct ttgtccttat
    17041 ttttgacaaa accgattgca actcctatag caaataagat atccaagttt ccaaaaacgg
    17101 catttccagc tgcaccaatt actgggatgt tcagcatatc gtcagctgat aaacgcatga
    17161 tcaatcccgc taatggcatc gctgcaactg gaagtagcat cgctcttcca agcttctgca
    17221 catttgattt aacattcatt tttattcctc ctctattaaa tatcctcata tgttactaac
    17281 tcaatcaaag gatcattttt cactttttga gcaaatgctg aatgaattaa aaattcgact
    17341 tggtgggtac gaggatacac aaaacttgaa ccatttaaca attcctgatc caaatacgct
    17401 gcgtgacaca tgacttcgat cgttttatct tctctcaata tcatgagtaa acttgccaaa
    17461 tattcttcca cactcgtatt gatttgtcgt tttttttcat cagtttctcc tacgacatcg
    17521 aaacaaggct caaaataatc gacatgacga acttcatctt ttcgttcaaa gttgctccga
    17581 accggcaaat catatttttt tgctaatgta acaactacct cctgattttc atccaaagta
    17641 tgagtatgat gatgactgtc taaatgagtt ggtatgatcc ccgcatgata aattttttga
    17701 atctgagcat tccattcctg atacagttga tctttgtcaa tgttaaatgg atgctgataa
    17761 taagataagg atctgaactc tccgctttcg ataagagtat cgacagtttt gaggagtggt
    17821 ttgccacacg tcaatgttaa atggactcct acacctagcc taggcatttc ctttcttagt
    17881 ttcacagcat gctcgaaacc cggcatattt gccatcaatg tagttgatgt caaaattcct
    17941 cgctgataag catccataat cccataattc acaccatggc tatagccaaa atcatccgaa
    18001 ttaaaaatca cttttcccat ttcattctcc ttcttttttc tactaaaata ggcgcaacca
    18061 aataatcata gtccatttac tatgtgtcat ttggttgcgc ctatagatag ttacgccctt
    18121 attttaatag attcttgcta gatgaattgc caaatagatg atttcatttt cttgaatggc
    18181 aagttgaaat tgctgttcga tgatatcttt aatctttagt gctgtacaat acgctttgct
    18241 atgtttaaat gtttcagtaa aaaaaccaat attttctact ggcgtttctt cctgataaat
    18301 caagcgttta accaggaatt tgatatgaac cattaagcga tgataagtca gtgattcttt
    18361 atcataaacg tttgaatagg atttttctag atgggacaaa atcgtggtcg tcatttctac
    18421 tatttttaag ctctttaaac tattaggctc tcctagctca gcattaatga tatgcatagt
    18481 gatgaatcct acttcatttg accctaactc ggtttgatat cgatgattga ttcgctcgac
    18541 cacttctact gctatatcat attcatttgg ataaaggaat ctcatttctg gcaacataat
    18601 tgctgtgaca tctctatctt ctctttttcg ttgaatagca aaataaatat gatctgtcaa
    18661 tgtaatatag atatttgaat ctaatggaga ggagatccta gctgttatca gttcaatcac
    18721 ttcttccgca aaatccataa attcgattgg aatctgcgag actatctcac tgaatcgttt
    18781 gatcttttct ttagaatcta atacaaataa tttgtcagca tcctcaacat caaatggctt
    18841 actcacttta gcagaaaagc caatcccttt ccccatcgca attttttcta ttccatcgtc
    18901 atcgatcaat acagcattat gattcagctt tttcatcaca tacaccgtta attcacctcc
    18961 tctatatgat aaaacaaaac aacttgcaga ctccttcata catatttttg tctccaaaca
    19021 atttttaaag acaaaaaacg acctaagaaa gaaccctttc ttaggtcgtg cctaattgaa
    19081 tagtagcacc ctacataatt tacaaaaata gtttaacaca taataaaagc gttatcaata
    19141 tcttttttac tcgttttatg ataatacttg tatcgaattg atttggaggt aattacataa
    19201 aaacaaaaaa aatatagcaa ctctctataa gaaagttgct atattgataa ttataccggc
    19261 ggccggggtc gaaccggcac gtcctcaacg gacactggat tttgagtcca gcgcgtctgc
    19321 caattccgcc acgccggcaa atttaaaaat aataactggg gtagctggat tcgaaccaac
    19381 gcatgaggga gtcaaagtcc cttgccttac cgcttggcta taccccaaga ataaaaggcg
    19441 aatgatggga atcgaaccca cgaatgccgg agccacaatc cggtgcgtta accacttcgc
    19501 cacattcgcc atcataaaag atgttattta atttctcaat aaaaaactaa gatgaagaca
    19561 tcttagtcaa taccggcggc cggggtcgaa ccggcacgcc ctcaacgggc actggatttt
    19621 gagtccagcg cgtctgccaa ttccgccacg ccggcaagtt gatttattag tactaaggcg
    19681 gtaaccggat ttgaaccggt gatgaaggtt ttgcagacct ctgccttacc acttggctat
    19741 accgccatta tactattatc aatctataaa ataaagaata aattatagaa actggggtag
    19801 ctggattcga accaacgcat gagggagtca aagtcccttg ccttaccgct tggctatacc
    19861 ccaagaataa aaagggcgaa tgatgggaat cgaacccacg aatgccggag ccacaatccg
    19921 gtgcgttaac cacttcgcca cattcgccat ggcaggggca gcaggaattg aacccacact
    19981 aacggttttg gagaccgctg ttctaccttt aaactatgcc cctataaaat ggaggagagt
    20041 ggattcgaac cactgaaccc taaggaacgg atttacagtc cgtcgcgttt agccacttcg
    20101 ctactcctcc atggtggcgc gggacagaat cgaactgccg acacacggag cttcaatccg
    20161 ttgctctacc aactgagcta ccgcgccata ttttaaaatt attaattgaa taacaagaac
    20221 gacggttccg acgggaatcg aacccgcgat ctcctgcgtg acaggcaggc atgttaaccc
    20281 ctacaccacg gaaccagttc attatggagg ttaacgggat cgaaccgctg accctctgct
    20341 tgtaaggcag atgctctccc agctgagcta aacctccaac attcaattaa aatgacccgt
    20401 acgggattcg aacccgtgtt accgccgtga aagggcggtg tcttaaccgc ttgaccaacg
    20461 ggccaggtaa atttgctacg gagagtaagg gattcgaacc cttgagacag tttggcacca
    20521 tctacatgat ttccaatcat gctccttcgg cctctcggac aactctccag agtgaaagaa
    20581 gctcaatact ctttctcaaa atgag
//
LOCUS       DAZKCH010000051        20445 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000051 DAZKCH010000000
VERSION     DAZKCH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.051"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            172..870
                     /locus_tag="ACG84X_001841"
     CDS             172..870
                     /locus_tag="ACG84X_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFP9127694.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(1038..3677)
                     /locus_tag="ACG84X_001842"
     CDS             complement(1038..3677)
                     /locus_tag="ACG84X_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFP9127695.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(4296..5327)
                     /gene="queA"
                     /locus_tag="ACG84X_001843"
     CDS             complement(4296..5327)
                     /gene="queA"
                     /locus_tag="ACG84X_001843"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFP9127696.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            5520..6694
                     /locus_tag="ACG84X_001844"
                     /pseudo
     CDS             5520..6694
                     /locus_tag="ACG84X_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly.; frameshifted; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
     gene            6698..7339
                     /locus_tag="ACG84X_001845"
     CDS             6698..7339
                     /locus_tag="ACG84X_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127697.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            7336..8253
                     /locus_tag="ACG84X_001846"
                     /pseudo
     CDS             7336..8253
                     /locus_tag="ACG84X_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
     gene            8250..8921
                     /locus_tag="ACG84X_001847"
     CDS             8250..8921
                     /locus_tag="ACG84X_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127698.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(9462..9950)
                     /locus_tag="ACG84X_001848"
     CDS             complement(9462..9950)
                     /locus_tag="ACG84X_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFP9127699.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(10151..10417)
                     /locus_tag="ACG84X_001849"
     CDS             complement(10151..10417)
                     /locus_tag="ACG84X_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFP9127700.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(10417..10680)
                     /locus_tag="ACG84X_001850"
     CDS             complement(10417..10680)
                     /locus_tag="ACG84X_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFP9127701.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            11201..11341
                     /locus_tag="ACG84X_001851"
                     /pseudo
     CDS             11201..11341
                     /locus_tag="ACG84X_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(11483..13306)
                     /locus_tag="ACG84X_001852"
     CDS             complement(11483..13306)
                     /locus_tag="ACG84X_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFP9127702.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(13904..16609)
                     /locus_tag="ACG84X_001853"
     CDS             complement(13904..16609)
                     /locus_tag="ACG84X_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFP9127703.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(16915..17862)
                     /locus_tag="ACG84X_001854"
     CDS             complement(16915..17862)
                     /locus_tag="ACG84X_001854"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFP9127704.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            18052..18321
                     /gene="rpsN"
                     /locus_tag="ACG84X_001855"
     CDS             18052..18321
                     /gene="rpsN"
                     /locus_tag="ACG84X_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFP9127705.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(18497..18859)
                     /locus_tag="ACG84X_001856"
     CDS             complement(18497..18859)
                     /locus_tag="ACG84X_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFP9127706.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(18870..19991)
                     /gene="alr"
                     /locus_tag="ACG84X_001857"
     CDS             complement(18870..19991)
                     /gene="alr"
                     /locus_tag="ACG84X_001857"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFP9127707.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(20007..20357)
                     /gene="acpS"
                     /locus_tag="ACG84X_001858"
     CDS             complement(20007..20357)
                     /gene="acpS"
                     /locus_tag="ACG84X_001858"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFP9127708.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
BASE COUNT         5807 a         4365 c         3838 g         6435 t
ORIGIN      
        1 cataatcgtt tcaagtgctt tttgcaagtt ccctcggctt ccttctactt tatttaatat
       61 tctttttttt atcctttttt tatgaataac aaaaaaaaga aaaacattat gacagaaata
      121 ttttttgata catggtatat tggtgttatt aaagaaaagg agggaaaaat catgcaatct
      181 tctgcagaat taaaacgcca agcaaaagag agtctaaaag gacgttgggg acaagctgtt
      241 ttactaaatc taatccctac attgattggt attgctacta ttcttcttat tatgattcct
      301 attatcttgt ttgccaccac catatatgat ggatcagcga gcgtctcaga agcgacaact
      361 tcaggaggcg gtagttcagg aggcggtggc ggaattattt ccagcatcat tagcgctttg
      421 ttcatgagcg gtatttcttg gacttatctt gatattttac gtggacaaaa agatcagatc
      481 gaaccattca aagatgcatt tcgtggattc aaaggtttgt ttatcggcgg agtgatcagc
      541 ttagctgtgc tgatctcgat ctttacaaca ttatggggtt tgctattagt tattcctgga
      601 atcattaaaa gctattctta ttctcaaagc tattttattt actacgatat cgtccaagaa
      661 acaggacaaa cacctaaagt actggatacg atcactgcaa gtcgaaaatt gatggatggt
      721 tataaaggac aacttttctg gttagatctt tcatttatcg gctggcatat cttagcatta
      781 gcaactgctg gtattggtta tctatggctc agcccataca tttctgcaac aaaagcagca
      841 ttttatgaac aattgccaaa agatatttaa aagagagtgt gacttgtgac cgagggggtg
      901 gcaggagaac accgtttatc gagaggcagt aaaagaaaca ttcagcccat tagcaaaaag
      961 gaggtgtgac aacattcatg tcacacctcc tttttgtata gttccagtaa aaagaaaatc
     1021 aacttagaaa cagttaatca ttcctcttct tctgcttccg gtaatcgatg gaacttgatc
     1081 agttcattca ccgcgattgg tacgatagat aaaatcccta ccaagaacca gtgattcaaa
     1141 ctgatgtgta ctaggccgaa tagttcttgc gtaaatggca gcaaagcaac agccgttgta
     1201 atagctaatg ccagtaacgc catttctacc aaagctttat tggtcgctaa attgactttg
     1261 aagatcgatt ggctgctgcg tacattgaac acatgcagaa tcgatgaata agctaagatc
     1321 aagaatgcaa cagtttgacc gacatgctga cttgcgtcta cccatgggct gatagtatcg
     1381 acataactac ctaaataata accaaacaag gttacgatgg tgaagacccc tgcatttatg
     1441 gcaatttttt gcaataaacc tcgagcaaag atcccttcat ttttcggaat gggtggctga
     1501 tccatgatgc cgtgttccgc tggctctctt cctaaagcaa atcctggaag tccatcagca
     1561 actacattga caaacagtag ttgcacagct gtaaatggtg ctccccatcc taacagcatc
     1621 gcaatcaaaa caataaagat ctccgaaata ttacagctta gcaaaaagtt gatagcttta
     1681 cgaatattct gataaaccga acgtccttga ctgacagcgt ctacgatcgt cgcaaagttg
     1741 tcatccgtca aaatcatatc tgcggcactt tgcgccacat ctgttcctgt gatccccatg
     1801 gcacacccaa cgttacttgc tttcaacgct ggtgcatcat tcacaccatc cccagtcatc
     1861 gctacgactg cacccgtacg ttgccaagat ttgacgatcc ggatcttgtc ttctggcgtt
     1921 acccgagcat agacagagag agctttgaca cgcgcatcta attcttcgtc tgataattga
     1981 tgcagttctg atcctgaaag tgcttctgac ggatcattca agatacctaa ttctttcgct
     2041 atggcactgg cagtcaccac atgatctcca gtgatcatga ctgttttgat gccagccttt
     2101 ttcgctcgct tgattgctcc tttactttct ggacgtggtg gatcgatcat tccgatcaga
     2161 ccaatcaaac gtaagtcttt ttccagtgct tcagaagaaa tatcttgcgg ttcttcgtca
     2221 taagtagcat aaccaacagc aatcactctc agtgcccgtt taccaaagcg atcattaacg
     2281 atcgccgctt gttctacatc gcctgaacta aagcgcggag caagaacatc gaatgctcct
     2341 ttggtgattg agatgtattt ttcgcccatt tggtgaactg ttgtcatcat ttttcgttca
     2401 gaatcaaaag gaagctcgtt tactcgtgga tatttttctt ctaattctgc ctttgtatga
     2461 taattctctt caacagccct tacgatggct acttctgttg gattaccttt gataacaagg
     2521 tcgtcatctt cttgctcgac cgtcacatct gtacatagtg cagccatttt caatatttcc
     2581 atcgcgctgt tcgtcattga atcttcgata ttcgttactt catcttcttt gctccatacc
     2641 cggcggacgc gcatttcatt ttgtgtcagc gttcctgttt tgtctgagca gataacatta
     2701 gcggttccta gcgtttcaac tgctggcaac tgtcggatga tcgcatgttt cctcgccatc
     2761 ttctgcacac cgtatgcaag tgtcaacgta acaataacag tcaaggtttc cggtacagct
     2821 gcaacagcca aggaaatcga agtcatgaac atctcaagga gtggttctcc ttgcagttca
     2881 ccaatcacaa atactaaagc cgcagccgct aaagcgatca tactgattcg tttgcctagc
     2941 tgattcaatc ggacctgtaa aggtgttttt tgcatagtat tttcgttcaa aagatccgcg
     3001 atcttaccca tttctgtagc catgccaatg gcagtgacga tcgctttccc acgacctgca
     3061 gcaaccgtac atcctttaaa taccatatta agttggtcac ctaatgactc atcttcttca
     3121 gcaataaatg ctgcatcttt ttcaactgct tcactttctc cagtcaacgc cgattcttct
     3181 acacgtaatt gtgatgcttc gatcaaacgg gcatcggcag aaatagcatc accggactct
     3241 aaaacaagaa tatcacccac taccagttgc tctgactcaa cagtggtcac tttgccgtct
     3301 cgtatgacag ttgccgtttg tttattcata tcttgcaagg attccagtgc tttttctgcg
     3361 tttccttctt ggacaatcgc caataccgag ttgatcacaa cgatagcgat gatcagcagt
     3421 ccttcaaata aatccccatg ttctgtagca aatgcggtat aaaaggaaat caccgctgct
     3481 acaagaagga tgatcgttgt aaaatcggac aagcttcgaa agaatttttt gatcatcgat
     3541 tctttcggcg cctcatcgaa tttattcaat ccctgctttt ttcgccgttc atccacttct
     3601 tgtgaagaca acccagtatc tggatctgct tctgttacct tctttacttc ttctattgtc
     3661 tgcttgtatt cttccatcct attcctcctt taaaatcttc gtacaaaaaa aggtacttat
     3721 tttactataa catccttttt ttatttactt caaataaagg gcttatcgat tatttgttaa
     3781 gaaagcgtaa aatttaaagt gcttatattt gcaaacgcta ccaaaggatg ctattatata
     3841 gatgtaagga aggaggatac catcaaatag acagaagaat ttctcgatag aacagtgtaa
     3901 gcaaacaaag ttgttagaag tacaggtttc acccagacat gcgtgtagag tacaaaccta
     3961 taaatagtga atgcgtatgg atgtttggat cacgaagtat ccgaaacaag aagtaatgcg
     4021 atacgtaaca attgaataac gtaaacgtct gaaaattgaa taggaacaag agatgtttca
     4081 aatgttgaag atgtaacgaa aacaaaattt ttgtttaaca tgaagaaatt caacaccgtg
     4141 ctttgcatgt atgatggaaa gttacaatca tttctgttta tttgaatcct tccgaggtac
     4201 aagaaagccg agcttatcga gagctcggct ttttctttgt cataaaatct ttgtaaagct
     4261 tttttgttat tcaaaactag cggcttttca taaccttatt tcacgaacat cgcatctcca
     4321 aaactaaaga aacgatagcg ctcttcaatc gcatgctggt aagcagataa agtcaattct
     4381 cttcctgcaa aggcactaac taacatgact aaagtcgatt ttggcaaatg gaaattagtt
     4441 gagaaagctt ctaccacttt gaattcatag ccaggcgtaa tgaaaatatc agtccatccg
     4501 ctgtctgctt tgatttctcc attaaatttc gttccaatcg tttctaatgt tcgaattgaa
     4561 gttgttccga cagccacgat tttcccgcca tttttacgta cttggttcaa tcgctcagcc
     4621 gcttcttccg tcaaacggta gaattcacta tgcatatggt gttcttcaat tttatctacg
     4681 ctgacaggtc ggaatgtacc taaccctaca tgtagtgtca gatagactaa ttcaacaccc
     4741 tttgcttcga tctcatcaag taattctttc gtaaaatgca atccagctgt tggcgctgca
     4801 gcagaaccat tttctttcgc atagacagtt tgatagcgat ctgggtcttc cagacgttct
     4861 ttgatatatg gaggcaatgg catttctccc aatgattcaa gaatctctag aaaaattcct
     4921 tcatactcaa agtcaatgat ccgtccgccg tgttccaatt cttctttcac tactgcttgc
     4981 aatctgccat caccaaaaga gattcttgtc ccaactttgg cacgtttcgc aggtttgatc
     5041 aatgtctccc acgtatctcc ttgtgtattc gttagaagaa ggacttctaa atgcgcacca
     5101 gtatctggtt tttctccata taaacgagca ggcagaactc gtgtattatt cataactagc
     5161 gcatcaccag gctgtaactc ttcaatgatt tcatggaaat gtttatcttc catctctcca
     5221 gttttccgat ccaaaacaag taaacgagaa tgatcgcggt cttttaatgg tgtttgtgcg
     5281 attaattctt ccggcaagtc aaaatcaaaa tcttctgttg ttaacatatc gtcactcact
     5341 ttctatcatg tgcttcatca ttctatcatg tttttcgttc tgttggcaaa atcagcactt
     5401 tttcacttct attttttgtt ttcctaaata aaaaaactac cctatttgta ttttttcatt
     5461 gttttaggca tactagtaat agatagttct tcattgaaaa tagaaaaaga ggtggcacca
     5521 tgattgaatt tcaaaatgtg tcaaaaattt ataaaggtgg aaaagtcgct gtagaggacg
     5581 tcaatctttc atttgaaaag ggtgagttca tttgttttat cggtacgagc ggaagcggaa
     5641 aaacgacgac gatgcggatg atcaaccgaa tgactgatcc aacacaaggg aaaattttga
     5701 ttgatggaaa atccatccaa gaaattgatc cagtggaatt gcgacgtcag atcggctatg
     5761 ttatccaaag tattggattg atgcctcaca tgacgatccg tgaaaatatc actcttgtcc
     5821 aaaaattgtt gaaagtcagt caagaagaac ggaataaaac agctgaaaaa atgattgatc
     5881 ttgtggaatt gccccgtgag atgttagatc gctacccaca tgaattatct ggtggtcagc
     5941 agcagcgtat tggagtcgtt cgtgcccttg cagcgaatca agatatcatc ttgatggacg
     6001 agccattcgg tgcgcttgat ccaatcactc gtgattcctt gcaagacctt gtcaaagatt
     6061 tacaagagcg tttgggaaaa acgatcgtat ttgtaaccca tgacatggat gaagcgatta
     6121 aactagcaag ccgtatcgcc atcatgagtg aaggccgtgt gatcaatttg atacaccaga
     6181 aaatatttta cgtcatcctg caaacgattt cgtagaagag ttgattggag aagatcgcct
     6241 actacaagcc aagccaaatg cgacaagagt cggcgaagtt atgctaaata cagcaatcac
     6301 gattacaccg gaaaaatcat tacaagaagc aatcaaactg atgagggaaa aacgtgtaga
     6361 tacgttgtta gttaccgata attcgaatgt attaaaagga tttatcgatg tagaaacgtt
     6421 gaataaaaaa cgaggaaaag tatccagtgt cggcgacatt ttgaataaac atgtttttta
     6481 cgtaaaagaa tccgcctatc ttcgtgatac cttgcaacgc attttaaaac gcgggctgaa
     6541 atacgtgccg gtcgttgatg aacagaacaa agtcgtaggt atcctgactc gtgcatcatt
     6601 agtggatatc gtctacgatg tgatttgggg agaagatccc gcaactactg atgttgcaga
     6661 gtcagctact cctgaagaat ctaaggaggt ctgacctatg cagcagtttt ttcatcagca
     6721 cggttcagaa attctctcaa aaggttttga acatctttat atttcaggac ttgctttgat
     6781 cattggtatc atcattgctg taccgcttgg tgtcttactg acacgttttc caaaagctgc
     6841 cacgattgtg attggcttaa ccagtgcctt gcagacaatc ccttctcttg ctttattggc
     6901 attgatgatc ccgctatttg gcgtaggtaa attacctgcg attatcgcac tctttattta
     6961 ttcattattg ccgattttac gtaatacgta cattgggatg aaaaatgtcg attggaatta
     7021 tcgggatgtg gcaaaaggca tggggatgac tgagttccaa tccatttttt ccgttgaatt
     7081 gcccattgct atgccaacga tcatggctgg tattcgttta gctgccgttt acgtgattgc
     7141 atgggctaca cttgcctctt atatcggcgc tggtggttta ggcgatttga tttttagtgg
     7201 actgaataat taccaaccag atctcatttt ggcaggtacg atccctgtaa caattttagc
     7261 actattggct gattggcttc taggtctctt ggaacaccgg ctgacaccga tcgcacttag
     7321 agaggagaat gaagaatgaa acgtatacta aaaatgacca tggttctttt ctctcttctt
     7381 atacttgcga gttgttcctt ccctggtctt gccagcaata cagatgaaga caccatttcg
     7441 atcacaggtg gaatcacttc agaagcacag atcttagcaa gtctagttgc cggaatggtt
     7501 taacattata cagataaaaa taccgcaatc atcaacaatc tggctactac aactatcaac
     7561 catcaagcga tgatgaacgg agatgcttca atttcagcgg ctcgctacac aggaacagat
     7621 ttaacgacta cattgaacct tcctcctgaa aaagatccga aaaaagcgtt tgctaccgtg
     7681 aaagatgaat ttgagaaaag atacggtcaa acgtggttcc cgtcctatag ttttgaaaat
     7741 acgtatgtct ttcttgttcg aaaagacacc gcacaaaaat accatctatc taaagtcagc
     7801 gatctgaaaa atgtagcgga tgaattagta gctggtgtag atacttcttg gatcaatcgt
     7861 aaaggagacg gttatgacgg cttccaagaa acttatggct tctccttcaa ttcgatatta
     7921 cctatgcaga ttggacttgt ttatgacgca gtcgaagcag gaaaaatgga tattgttctt
     7981 ggctactcta cggatggacg gatcgccagt tatgatctag tcatgttgga agatgatcgt
     8041 caattcttcc caccatatga tgctgctcca gttgtagaca acaagatatt agctgatacg
     8101 cctcatttaa aagaagcctt aaataagtta ggtcatacca tcagtacgga aaaaatgcag
     8161 gaattgaact acgaagcaga taataatcta gtggaaccat cagtagtagc acaacgtttc
     8221 ttacaagaaa accactattt tgaagggaag tgaagcaatt ggataaaatg aatgtctttc
     8281 aacaattttt ctattatttc caggaaaatg gctcctatat ctttgcacaa tttatccgtc
     8341 acttcctgat ttctatctat ggtgtcctct ttgcagcagt tgtcgggatt ccggttggga
     8401 tcatgatttc taggagacgt aaattagcaa actgggtgat tcgtttggcg aatatcatcc
     8461 agacgatccc ttctctagcc atgatctcca ttttaatcat tggattaggc ctgggagtca
     8521 atgtcgtgat tgttactgta tttttgtatt ccctcttacc gatcatcaag aatacgtata
     8581 ccgggatgat ccaagtagac aaaaacatcc ttgatgtcgg caaaggcatg gggatgactg
     8641 ctagacaacg actattcatg gtagagttac cactctctgt ttctgttatc atggcaggca
     8701 taagaaacgc gttagttgtt gccatcggga taaccgcgat cggtgcattc gtcggtgctg
     8761 gtggtcttgg agatatcatt atccgaggaa ccaatgcaac agagggcaca tcgattattt
     8821 tagcaggtgc attgccaact gcattaatgg cgatcatcac ggactggctt ttaggtattt
     8881 tggaaagacg gctagatcca gccagccgta catcacgctg atgttattgt aaaaaacaaa
     8941 agcttctgcg accatttgtt ggtcgcaaag gcttttttag ttctgtcatt tttaaggcaa
     9001 taatccactc tgattcttcc ctccttatgg gcaaagagtt gcttttctta gctatttatc
     9061 cattccgtat actccaactt catactgcca acgggttcat atctgcatcc accgactaag
     9121 tttttttctt atccgctaag gcattttgcc aatccatttt cccatcactc gtcatggaat
     9181 tcataccaca tgatctctaa atactcgtct gcttgttctt tgaattgggc atcaattctt
     9241 acatcctttg gcgtggcttt catttaagcc ttttccatca gtcctcgatt gttcgatgcc
     9301 ttcagctgca tcatcaaaac tggtgactgc cgtatcggta acttcgatca tcttttatac
     9361 aatcgggaac ttgccatcct catccttggc taaaaacata tctagccatt ccagcttctc
     9421 gccatgggag gtttgcggtt cctaaaaccg gtacacgatt cttatggact gcatccgtcg
     9481 caactagact tggcgatacg atgatccttc accagaagag cacccccgta aaccaattga
     9541 tcgatatatt gccaataaga aaagacattg gcgtaaaaga tatcgatccc tcgtgatgca
     9601 ttgccgttga tactgctatt catggccgaa agcgccacga ctttaacttc ttccgtttga
     9661 gtgacattca tgttcggcaa tgtcgctttg gatacccgct ctgctaaagg aacgacactg
     9721 gtattgtatt tcgtatctgt atcttttcca aaagaccatg ccaacgaatc ctctgggaac
     9781 caataagacg actccggttg attgtccatt gcttttttca acatactttt ggctgtttct
     9841 cgataaacga catttccaat tgtcttcgcc tcactttggc gataatcgat ggtcgttgcc
     9901 actgccaaca ctaacaacga tgctccaatt ttactgattt tccttgtcac acttcttcct
     9961 ccttgtttta cataaacccg tcaacattcc attcctaaac tcaaacaatg acccttcaaa
    10021 ggtggagata taggaacaaa ttaaagaaat catgcaataa atccaagaag gttggtttta
    10081 gaacaaaaaa agagtctcct ttttggggag actctttgtt aactatctaa aaaggttggc
    10141 tcttctcact tcactcataa tgtgtccagg cagaataaat ttctacaact ttattttcct
    10201 catcaacttt gtaaaccact cgatgctgtc tattcagcct gcgtgagtat ctgccttcat
    10261 gtgtaggtct cagcttttca aaagactgcg tgggcatata tggatcttcc ttcaatgtct
    10321 gaatcacttc ttcaaattgt ttctttaaat tcgtttgctt gatttttctt aaatccactt
    10381 tcgcagagtt tttgattgcg actgtatagt tactcatcaa agagcttccc aatcaatatc
    10441 atcgatattc gtaaagctac tgtcgtcttt ttcgcggtct cgtactttat ctaaagtacc
    10501 tgtttgctca agaaaaaggg tttcttgaat cgctctccag tcttccagcc caatcaatac
    10561 agcattgttt ccactacgat cactaataat ctcgatttca gtatgatttt catttacctc
    10621 tttcaataac tgataaaaat ttttacgagc agtgctagga ttcatcgttg tattagccat
    10681 tgtctctcct cctttttctg atataattat agcgtacttg attaagtacg tcaaaaaaat
    10741 acaataaagc acttaaattc agcaaacttt tcctcttttt tacatagaga aaaagacccc
    10801 tttttaggga ggatctttgt ccacgctcac ttcttactcc tttacgacta gcggtagcca
    10861 aacgtaaagt aattggtaac aacgtatcat ctttagcaaa ggtcgaatcc aaagcctgtg
    10921 agtctatgca acaacaccaa tacacgaagg ttcctcgttg cagtgtgact tgattgatat
    10981 cttgaataac ctgaggatac gcacgaaaga tttgtaacgg ttattcaaaa ctgattttgg
    11041 ccgtcaagtc ttctactgcc tcaaaaatga ttgcctcttt cgtctcctgt cattcatgtt
    11101 cactatcgat ttgatacttg cttagaccgt tgggtttgtg aatcaccaat taaaaatggc
    11161 actgagttat ggtaacaaaa aatggtcact tgacgaggct gagattccta cttatgaaga
    11221 cacatggcac ttaagagtcg aggtaaagga agaagctgaa aatataggag gctgtacatt
    11281 atttggcaaa ggattcggaa attatgatca agacatcaaa atcaaaatgt tttacagcta
    11341 aataggaaga ataataacat ttcatacgct gttcccatct ttaatggctt atagagggca
    11401 cctttagctg agaataagac aaaacagacc ctctagcttc aattaagagc tagagggtct
    11461 gtttttgatt ttaaaacttg gtttatttct tcaaatggta gctataggtg ctgacaacga
    11521 tattttcacg ccaagacaat cgcaatctta accgcaaact tgtttggtta tggagaatat
    11581 tctgccagcg tctgtttggt acaaattgag gaatcaacac agtagttgta tagttttgtt
    11641 tcgctgcatt tttacttacg atatctacat aacggataat tggattttca atcgagcgat
    11701 aagaagagtg gacgattgaa aaacggacat ctgggaaatg ctttttaaat tctgcttcga
    11761 tttctttttc tttttcgaca tcttcgtcta gcgaaacatg catcgcaacg acataatcac
    11821 cgatcgaacg tgcgtaattc aacgcaccga tatttacccg tgtcacattc ccgactaata
    11881 caagaacggt attcccgtca taatcatgta gttttgcatc attttctaaa cgaagctgtt
    11941 ctgctacttt tttataatga tcatggatct tataaaaaat gaacataacg attggcataa
    12001 tgatgaagaa aggccaaatg tcccctaacc gatagacaaa caaaatcgca atgattgcat
    12061 atgagatgaa cgcacccgta atattggcaa tcgatttgct taaccatctt tttccttctt
    12121 ttttccattt gacgaccatc cctgtttgag ataaagcaaa tggaatgaac acgccgatag
    12181 agtataacgg aatcaagcgt tctgttgagc catggaaaat aaacagcaat acgatcgaac
    12241 ctagcgctag tgtgataatc ccattggaat agcctagtcg atccccacga tcttgataca
    12301 tgtgaggcat gaatttatct tttgccagat tgtatgcaag aactggaaaa gcagaaaaac
    12361 cggtgttagc agcaactgct aaaatcagcg ctgtagcaaa ttgaaggacg taatacaaaa
    12421 taccatgtcc aaagacagct ttaccaattt gagacaaaac agtgacttct ttttcaggaa
    12481 cgatcccata ccaatagttg ataaatgtga tccccacgaa gaagaaacct aagatcaatg
    12541 ccatcatcgt caatgtagca gcggcatttt ttgctcttgg cttcttaaag aatggtacag
    12601 cattactaat cgcctccacc ccagttaaag aggaagaacc agaagaaaat gctcgtaaaa
    12661 tcaaagcgat agaaacaccc ggcacagccg ctcctggaag tgcagtagct tgcaatggca
    12721 cagcacctgt cacgatatta tataaaccaa caacgatcag taacgagatc acaaggataa
    12781 atgtgtacac cggaaataat aggaacgatg cagattccct cagcccacga agattcagca
    12841 tcatcagtag caaaacgatt gtcacagaaa tagcgacttg atgaccgtag agtgctggca
    12901 ccgctgatgt gatcgcttca gcacctgctg agacagatac tgctactgtc aacatgtagt
    12961 cgatcaataa agagccaccg gaaatcaagc cagcattctt tccaagattc tcactgctga
    13021 cgacatatgc tcccccgcca tgaggataag catggatgat ttgacgatat gatagcgtta
    13081 atgaaatcaa taaaataata acaaaagcgg caatgggtag cgaataccag atggctgcag
    13141 cagacaaagc gactaaaacg acaacgattt gttccgtacc atatgcaata gatgataacg
    13201 catcagacga caataatgcc aaagcagcaa atcgggttaa tttgtgctca tcattttcag
    13261 cagattttaa aggcttacct actaacaacc tttttaagta atccaatttc taaactcctt
    13321 tacacacaat tttacttcaa gttttatagt cgaaaattta tagtaaacaa gatgttatag
    13381 tacgctcact gaccttaaaa gtcaataaac tttaagaaaa taattggaaa aaaacagaaa
    13441 aatatcaagc gctttttcaa acgctttaat acagcaaaaa tctaacattt ttttatgggc
    13501 tttttctttg aattctataa taaaaggata gaacttgact tagaaaatca agttctatcc
    13561 tttttgatat cttaactttt ggaagagaga tgtaaggctg ctttctaccc atcattctta
    13621 ctactcgaag catagcgcag ttgtcacaac ctcttgataa acggtgttta aaagcttgca
    13681 tctgcggtaa taagcccaac caaattaaaa acataagaag ctgtttttat ttggtcgttc
    13741 ttattacttg atgcagagca gcttttttac aacctcttgg tacacggtgt tcaatcagct
    13801 gaccctcggt attagctcaa aaaaacggca aaatatgagg aactattttt ccattttttt
    13861 ctctaatact caggtcaaaa cactgatttc acaacctctt tttttaatga aaaatatggc
    13921 tctcatgcgc cgcttctttg aatttcgtca ttttttcttc gatgaacgga tagattgccg
    13981 ttcctacgat tccaaagaca acaaacaaac cgatcatgat ccagattgct ttcgtagcat
    14041 ttggccaata aattcctcct gcagattccc gtaacaagtt taccgcatga gtaaatggca
    14101 agaacggatt gatcatttgg aagaatttcc ctgagacttg gatcggatag ttcccgcctc
    14161 cgccagagat cgacagtact aagatgataa tagcgatccc tttaccgaca ttatcgaata
    14221 atgcagccaa gacatagacg atcatcatga acgctaaggc gatcaagaca gcaaatgaca
    14281 cgctgtagac cggattttgg acatctactc ctagtaagaa aatattccct aatgtaacga
    14341 tcaagctttg cgcaatcgcc attgtcaaaa atgtcagcat acgagcaacg aattgttctc
    14401 gtttcgtaaa attgtttcgg tctttctttc ctaaatagta ttctgtcgta gcaacacttg
    14461 aaagaagaac agcgccgacc cacagacata gtgcagtata aaacggggtg ctagctgaac
    14521 cgttatttgc gattggataa agcgcattgg tttgtagctc aacaggttgt gtaaagaagt
    14581 cactttcttt tgttgcgtct agtttcaata atttgatgac ttcgcctaga tcgacttctt
    14641 gttcgccttt tcggatcgcg tctgctgctt tttggatacc agctttgata tttggccagt
    14701 cattgttgat caagtccgca gcagcgttca cagctgtttc gacttctggc attttttcat
    14761 ttactgttgt caatgtaccg gtgatttcat tttttagtgc tggccaatca ttttggataa
    14821 aatcagcggc caatcctaat ttttgctgaa tgatcggtaa ttcattgttg tataggtctg
    14881 ccccttcatt gatgccattg acgatggtat ccatatttcc attcagcatt gtattggcat
    14941 catggatttc ttgtccaatt gcaggcattt ctttttgata tttttctaaa attgccactg
    15001 cattcgttac agttgctttc gttgagctga gaagcgaatc aaagtcgatc tggtccgctt
    15061 tgctcagtgc gccttgtgca gtcccaatcg tatcgatgac ttggtctagt agagaagtga
    15121 cagtggaact gatttgacct gtattgatac cagcaatgat gccattgata ttattaacaa
    15181 cggcatcaat ttgatctagc aattcatcaa tagccttcgt gtcttcattt tgaacagctg
    15241 tgttcaaagc agataggcgg ttttgcagat tgcttagcaa gggttttaat tgatttagct
    15301 gatcaataat tggctgtaat ttcgtatttc cagcacttgt ttgcaattta gtcaggaact
    15361 cgaccagttt atcgattgca ttttgttgtt gagatattcc gtcaataaag ccgttcaata
    15421 cattgctgat gtttttcttt tcatcatcag tcagcttacc atcttcaata gctgttctta
    15481 cagtatctat taacgaacct gtcgttgttg ccacttgtcc aattgacttc aatgtaacat
    15541 ctacactgtt tgtgatgctt ggtatcgcat ctttcagctg agaggcacct gattttgttt
    15601 ggtttgctag atcacttgcc tgattttcta aatttttcac atctggcaag atatcttgta
    15661 cttgttggat gatcgtcaag ccttgttttg cttcatcgat tccttggttc attgtctctt
    15721 ggatcgaagc aaaatcgccg tcgatctctg ctagttgctt accggcattt tggatctctg
    15781 ggattttttc ttgcaaatca aggatgattt ttgcttgatc tttcaactca ggcattttgt
    15841 cattcaatgc aacgactttt tcacccatct catctacttt agggatgtaa tccacgaatt
    15901 catttgcttt attcagtttt tccttgattt caggtagttg actttgtaat tcgaggactt
    15961 gttttgtgta gccgtcgatc gtgtccaaat tttcatctgt tgataaaatc atatctttaa
    16021 ctttattgat acttactagg ttcgtatcga tgtcgtaacc tatctcattg aatactttca
    16081 ataaagtcga actggctgtt ttgataaatt catttgtgat ttgcgattgg atcgaacttg
    16141 ctcctttatc ggtgattttc ggtgcaatcg cattgatttt ttcatttacc gtatattcga
    16201 tttttggttt cttgatatca ccactagtaa aactcagcag atcttctgag aaatcctttg
    16261 gcaagtaaat acctgcgtaa tactttccgg aacggactcc gtcttctaat tgttcttttg
    16321 aatcaacgaa ttgccatcct aattgtttat ttttatgaag cgattcgatg acttgctccc
    16381 caatggccac ttctttacct tgaaactctg ctggcttgtc tgcactgtaa acagcaattg
    16441 gcagctctcc agtatttcca tatggatccc ataatgcttt gatgttaaac cacgcatata
    16501 gcgaagggat gatcatgatc gcgatgatca gaagtgttgc aatcgggttt ttgaaaatcc
    16561 gtttccagtc aagcaaatat aatcgaagcg tatttttgat tgactgcata gttctccccc
    16621 ttcttctttt ttcagctgaa ttactttacc atgtatttca tacttttttc aatcggcttt
    16681 tttcaaaaaa gtcgaatttt tggacatatc acggcaattg tctcattgta atctcttaca
    16741 tattgagaaa taattaagga ttacagcctt tactttatca tgaaataaaa gggaaagata
    16801 attttatgcc aaagttttta tctattatac gtatacgcaa aaaagctaaa acattttttg
    16861 tctttgcccc tacaaaaatg tttcagcttt tttcgttttt tattcctgta tttcttattt
    16921 ttcgaatgac aggatgattt tcccagcagg aggatgtcct tcaactagct gatgtgcttg
    16981 gatgacatgc ttaagtgaag cagacagatt cattgaaata aaaacatgaa aggctccttt
    17041 ttggtaggct ttgattatgc cagcaaaggc ttctgcatct agatattcct ttcttggaac
    17101 aaacgattca taaaagcctt cctttttttg ccgcaaatct agatctggga ggtcatttaa
    17161 tgcaacatac ctgccgcctg gtttcatgat ctggatgccg gtttctcctt tgatacttcc
    17221 tttcgtcgca tcgattacaa ggtctgcctg atcagcaaat tgcagacctg gatttgtttt
    17281 atcataagca gcaaatgctg aagctcctaa tttttttacc ttttcctcat ttttactgga
    17341 tgcactggtt aagattcgga ttcccttttc atggagaagc tggatcagac ttgacccgac
    17401 cgcacctgat gctcctagta tcattacagt atctgtcggc tggatttccg tcaaatggtt
    17461 gattagatta taagccgtaa ttcctggcgt gaccattccg gctgcttctt cccaactcat
    17521 tttatctgga atttttgcta cttttgctga tggcaacacg acttcttctc cgtaagtccc
    17581 gccgactgca tggacagcta ctcgatcacc tacatgaaca gttgtgacat ctgaaccaat
    17641 ctctgtcaca ataccagcgc catcattacc tggtacataa gggaatttca atgttcgtat
    17701 ctctttcatt tctcctaaac gcaaggcaac atcataagga ttcacactga atgcttttat
    17761 ttctacacga acatgtccag aaccgacttc tctgggatga gcatcgattt cttcaaaaac
    17821 atcttgtgct tctccgtaac cgttaattgc aaatcttcgc atggtcacca tctccctttt
    17881 tctttaagtt tacgtttatg cctttatttt gacaaaaaaa atgtcttttc gttttggcgc
    17941 atgattcaaa acaaaatagt tgtctttttt cgcgtaacgt gttaaattat ttatctaaaa
    18001 gcgtaaagat tacgatttac gctaataaaa aataattgga ggaatttgtt gatggctaaa
    18061 aaatcaaaga ttgccaaagc aaaaaaacag caagaaacga ttgaacgcta tgctgcttta
    18121 cgccaggaat taaaagcgca aaaagattac gaaggcttgc gtaaacttcc tttagatgct
    18181 cgtccagaac gattgaaaaa tcgtgattta atcgatggac gccctcgcgg atacatgcgt
    18241 aaattcggga tgtcccgtat aaaattccgt gaattagcac ataaaggttt gattccagga
    18301 gtaaaaaaag ccagctggta atccaagtct ggctgtaatg taaaggagga gggcgcatgg
    18361 accactcctt ggatcatcaa aaaagatacg ttcgcttctt ctagcagaaa tgctggtact
    18421 agaagcagac gtatcttttt ttacgcacag ctggtccttt tttatatgta aaggctgcat
    18481 ggttacttcg ctatatttat ttagtaacag gagtcagtgc ttcgataccc acactaattt
    18541 tcaatgctcg gtcaacttct gccataatgg gtcgatccaa atggcagacc ttttctttca
    18601 atcttgattt atcgatcgtt ctgatctgct ccaacaggat aacggagtct ctttctattc
    18661 ctgttccagt agctttgatc ccaatgtgag tcggaagctt aggtttagcc atttttgccg
    18721 ttatggccgc aacaatgatc gtcgggctaa aatggttacc tagattattt tgaataacca
    18781 aaactgggcg tgttccgcct tgctccgatc ccacgactgg agaaagatca gcaaaataaa
    18841 tatctcctct ttttaccata ggatcctcct tattcttgat attctcttgg tatccgctgt
    18901 cctaatccgc aagccacttc atagtggatc gtacctaatt gatctgctat atcctgcata
    18961 gtgatttctt tgtctgcatt tttgccgata agcgtcactt ttgttccgac aggaaattct
    19021 tgaggcaatc ggatcatcag ttgatccata catacacgcc caatcgtttc acagtagttc
    19081 ccttctacca atagagaaaa accctgcatc tttcgtggcc agccatctgc ataaccgatc
    19141 ggtatcgttc cgatccactc tgcttcagga gtgatatatg tttctccata gccgattcct
    19201 tcacctgctg ggagtttttt gacttgaatc aattcagaaa ccagctcaag tgctggctgc
    19261 aatggataaa cttccggtag tgcgtgccca gagggattaa gtccgtacat tgctactcca
    19321 taacgaatca tattgccgat tgtttcatca tgccataaag ccgttgcact attgctgaca
    19381 tgtacatatc gaggaagttc gggaagtttt ttcagcactt ctataaagcg ttctttttgc
    19441 agattccaat atgtatcatc tgcctgatct gctgtagaaa aatgggtaaa taaaccttcc
    19501 cattctaata cacgactttc tttgatgaat gcagctgcct cttttacttc ttcaggtgta
    19561 caaaatccga tacgacccat cccagtgtct gcttttagat gaatcgaaag aggcgtctct
    19621 agcttacttt tctctaaaac agcagctgct gcttgcaacc attcccgtgt acctgcagtt
    19681 actgataaat catgagcaac agctacagtc agtgcgtcgt aaggaaccat attcaagata
    19741 aggatgggct gagtaaatcc agcttctctc aactcgactc cttcatctaa atttgaaaca
    19801 caaaagcccg aagctccacc tgcaactgct gcctcagctg tttcaatagc tccatgaccg
    19861 tatccgttcg cttttactac tgcaaacaat tcttttcctt gcggaagtct tgcaacttca
    19921 tttgctacat tttcagttat agctttttta tgtatcactg ctttcgttgg gcggtgccaa
    19981 gcgacaacca tcgtttttcc ttctttctag tcttccaaaa taatttgtgc aaaagctgtt
    20041 tcatttgtat gagtaatact gacccataca ttgccttcat gaggtgaacg cgtcacaaca
    20101 ggctgaccat tttcattttt taaaatctcg acatcttgaa aggtaacttt tccgatccca
    20161 gttccccaag ctttagagaa agcctctttg caagcgtaac gcccgcctaa aaattctact
    20221 tggcgatgaa aaggcaagga ctggaatagt ttcatttcat cagaggtcaa gattcgtgca
    20281 atgaattttg gtttttcttc gatcagccga gtgatcctag gaagttcgac tgcatcgatc
    20341 ccaattcctt ttatcatatg cttttctctt ttcaataaat ttagaacact ctcattctac
    20401 caaattataa ccattttgcc acaaataagt ccacaaataa caaaa
//
LOCUS       DAZKCH010000052        20362 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000052 DAZKCH010000000
VERSION     DAZKCH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.052"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            291..1430
                     /locus_tag="ACG84X_001859"
     CDS             291..1430
                     /locus_tag="ACG84X_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFP9127709.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1497..2072)
                     /locus_tag="ACG84X_001860"
     CDS             complement(1497..2072)
                     /locus_tag="ACG84X_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFP9127710.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2077..3051)
                     /locus_tag="ACG84X_001861"
     CDS             complement(2077..3051)
                     /locus_tag="ACG84X_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HFP9127711.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3075..3119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3334..4302
                     /locus_tag="ACG84X_001862"
     CDS             3334..4302
                     /locus_tag="ACG84X_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9127712.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4415..4693
                     /locus_tag="ACG84X_001863"
     CDS             4415..4693
                     /locus_tag="ACG84X_001863"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9127713.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4811..5047
                     /gene="secG"
                     /locus_tag="ACG84X_001864"
     CDS             4811..5047
                     /gene="secG"
                     /locus_tag="ACG84X_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFP9127714.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5150..5905
                     /locus_tag="ACG84X_001865"
     CDS             5150..5905
                     /locus_tag="ACG84X_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9127715.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSL
                     AEHQLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5908..8265
                     /gene="rnr"
                     /locus_tag="ACG84X_001866"
     CDS             5908..8265
                     /gene="rnr"
                     /locus_tag="ACG84X_001866"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFP9127716.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8287..8751
                     /gene="smpB"
                     /locus_tag="ACG84X_001867"
     CDS             8287..8751
                     /gene="smpB"
                     /locus_tag="ACG84X_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFP9127717.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9053..9772
                     /gene="atpB"
                     /locus_tag="ACG84X_001868"
     CDS             9053..9772
                     /gene="atpB"
                     /locus_tag="ACG84X_001868"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFP9127718.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9825..10040
                     /gene="atpE"
                     /locus_tag="ACG84X_001869"
     CDS             9825..10040
                     /gene="atpE"
                     /locus_tag="ACG84X_001869"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFP9127719.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10131..10655
                     /gene="atpF"
                     /locus_tag="ACG84X_001870"
     CDS             10131..10655
                     /gene="atpF"
                     /locus_tag="ACG84X_001870"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFP9127720.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10642..11184
                     /locus_tag="ACG84X_001871"
     CDS             10642..11184
                     /locus_tag="ACG84X_001871"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFP9127721.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11207..12763
                     /gene="atpA"
                     /locus_tag="ACG84X_001872"
     CDS             11207..12763
                     /gene="atpA"
                     /locus_tag="ACG84X_001872"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFP9127722.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12777..13679
                     /locus_tag="ACG84X_001873"
     CDS             12777..13679
                     /locus_tag="ACG84X_001873"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFP9127723.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13702..15108
                     /gene="atpD"
                     /locus_tag="ACG84X_001874"
     CDS             13702..15108
                     /gene="atpD"
                     /locus_tag="ACG84X_001874"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFP9127724.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15122..15544
                     /locus_tag="ACG84X_001875"
     CDS             15122..15544
                     /locus_tag="ACG84X_001875"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFP9127725.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16013..16243
                     /locus_tag="ACG84X_001876"
     CDS             16013..16243
                     /locus_tag="ACG84X_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFP9127726.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16340..17641
                     /gene="murA"
                     /locus_tag="ACG84X_001877"
     CDS             16340..17641
                     /gene="murA"
                     /locus_tag="ACG84X_001877"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFP9127727.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17654..17830
                     /locus_tag="ACG84X_001878"
     CDS             17654..17830
                     /locus_tag="ACG84X_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFP9127728.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17965..18261
                     /gene="yidD"
                     /locus_tag="ACG84X_001879"
     CDS             17965..18261
                     /gene="yidD"
                     /locus_tag="ACG84X_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFP9127729.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18325..18708
                     /locus_tag="ACG84X_001880"
     CDS             18325..18708
                     /locus_tag="ACG84X_001880"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9127730.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18877..19761
                     /locus_tag="ACG84X_001881"
     CDS             18877..19761
                     /locus_tag="ACG84X_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9127731.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19875..20111
                     /locus_tag="ACG84X_001882"
     CDS             19875..20111
                     /locus_tag="ACG84X_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFP9127732.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20199..20279
                     /locus_tag="ACG84X_001883"
     tRNA            20199..20279
                     /locus_tag="ACG84X_001883"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20233..20235,aa:Tyr,seq:gta)
     gene            20286..20357
                     /locus_tag="ACG84X_001884"
     tRNA            20286..20357
                     /locus_tag="ACG84X_001884"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20318..20320,aa:Gln,seq:ttg)
BASE COUNT         6760 a         3567 c         4425 g         5610 t
ORIGIN      
        1 ttttttgcaa ctagcttctg tatatgatgt ttacaaagaa tggtacaaga aaagatcatc
       61 cttgaaaaag gaaagctaac aataactagc atcatataag agcttttaag gatagaacag
      121 tagaatagga atctatgggc aagtcctctc gtataaataa aataggaggg aagtagcagc
      181 atatttttca taaagtggct ctctttcttc atttttactt tggttgctcc tatttgaaaa
      241 ttcgagcaca ctcaaataca ataaaaagaa atggcaaggg agaggattag atgaaaaaag
      301 aagaaaaaat cgcgatttta caagagatta tccgaattaa atcagtgaat ggaaacgaag
      361 gtgaagtagc agcctatttg aataagcttt tggcaaggca tgacataaca ggagagattg
      421 tttcttacag agatggtaga gataatttga ttgctcgtta ccaaaagggc caatcaggaa
      481 aagtgttagg cctatctgga catatggatg tcgtggcggc tggtgatgaa tcgtcttgga
      541 cctatgcacc ctttgcagca gaaatccatg ggaaccgttt gtacggacgt ggtgctacag
      601 atatgaagag tggcttggca gcaatggtga ttgccatgat cgaactgaaa gagtcaggaa
      661 aaccatttaa cggaacagtc aaattattag ccactgtcgg agaagaagtg ggtgaactag
      721 gtggggaaca gctcacgaaa gcaggctatg tagatgactt agatgccttg atcatcggag
      781 agccaaccaa ttacagtttg atgtatacgc acatgggatc aatcaactat acagtcacct
      841 cgcacggaaa agaagcgcat agctctatgc cagaccaagg ttataatgca atcaatcacc
      901 taaatgaatt cattacgaaa gcaaatgctg aaatgaatca cctcgctgaa acaatcgaga
      961 atcctgtcct aggaaaaaca atccataatg ttacattgat cagtggcggg aatcaagtca
     1021 acagcatccc aagccatgcg cagctccaag ggaacattcg atcgattcca gaatacccaa
     1081 atgataaaat cattgcattg ctgcaatcaa tcgtcaatga attgaatcaa gagacagact
     1141 atcatttgga attgatgatc gattacaaca aaatacctgt caaagctgat ccagattctc
     1201 ctttgattca ttccattcag caacaattca gccagccatt acctttagtt ggagcggcag
     1261 caacaacgga tgcagccgaa tttacgaaag ctaaccattc cttcgacttt gtcgtctttg
     1321 ggcctggtgt cgttactttg cctcatcaag tagatgagta tgttgaaatc gataattatt
     1381 tggatatgat cgaaaaatat caaggaatta ttttatccta cttagcgtaa gattttttta
     1441 ataaatgaaa aaacagagcc agattagcat tattttgcta atccagctct gtttattcag
     1501 cctatttttc tttttgaata tatcaagcgt tggggcaaca tagtgatgac taatgaaaca
     1561 acgacgatag acaacaagcg atcaaggtag tctgtaccca cctgtaccaa gatcacactt
     1621 gttgtctgac ttaaacctaa cccatgtaat agctgaacga tcatactgga tcctgaggag
     1681 gtgatcccgc caaataactg aacggtaatg atcgaagaaa cgatcgttcc aggtaccgac
     1741 aaaatcaaag cgagtaataa cagtttcaag ctgtttttat ctttgccgag atatcttggc
     1801 aaaatcaatc cagcaagcaa gcctgtgaga atttggattg gcgaataata cagagaaaaa
     1861 atatctgtag tcactccact taaaataccg ctggacaatc ctgtcagcat tccaggtaca
     1921 ggcccaagca atgcaccagc aaaaatcgtt ccgatagaat cgagatagat tggcaaacga
     1981 agccataaag caatcgttcc tccaatataa ttgatcccaa tacacaaagc catcactgta
     2041 agtacgcgag ttgccatttt gtttttattc attttgttag cccatcttta acctttccaa
     2101 atctttcata atcgtttctt cttgtgcatt taaaagaacg gttaaaaact ttcggaaaaa
     2161 aagacgagta tctacttttg tcataatttt actgttagca ggtttctgcc aaaattcata
     2221 acgatcaacc aatgtttgtc cgcgacttat tccttgagtt tctacagcag tgaagctttt
     2281 aaagccttca cagatggact catcgataaa ataagcaaca gctaatggat cattgatgac
     2341 acatcctaag attctttctt gtttccagtg aaagtcaaaa taaaaacgag tgatcgcttt
     2401 tagatactct ccctcttcag gattcatttg gcagcaatat tcaaggatag tcggtgtcaa
     2461 gacgatttct cttgtcacat ctaacccaac catttctatc ggttgtttga gcttttcgaa
     2521 tacataagaa gctgcttcag gatcacacca gtaattgtat tcagcaactg gtgaacagtt
     2581 accatggctt ttgtaagttc cgcccattga gacaaaacga tccatatgtt tcccaacaga
     2641 tgggctgttt ttcaaagcag aagcgatatt ggtcaaaggc cccaaagcaa tgactgatgt
     2701 atctgttttt tctttgaaat aatcagtcag aaaatcaact gcatggagcg attctgcctg
     2761 tttggctaag accatcggga aatttgtgtc ccctaatcca tccaacccat gagtgtcttg
     2821 cgcactaatg aaaggttgct tcaaaggttt ttccattcct tgataaacag ggatatctaa
     2881 acgatcacag cgctccaaac atttcagcac attctgcgta ccgatatcta cagggacatt
     2941 cccgcaaacg acggtaatag caactacttc gatatcaggg gatttgacag ctagtgataa
     3001 agctaaagtg tcgtcgatcc ctggatcgca atcaataatt actttacgca ttatttccaa
     3061 tctcctttct ttagagatac ttagtttttt attctgggaa gtttccgaac cagtccaaga
     3121 cgagtgtctt gtttataatg cacgaaatta gtatactggc ttttattgtg aatgtaaatg
     3181 ctctcttaca agtaaatcta ttgagaagaa ctttaagtaa atgatacaat gaaaaagaaa
     3241 tggaatttac gtgtgccgaa gaaaaagaat cctattgatc ggtatattgt ataataaata
     3301 gattatagtt tggcagaaag cggcgggtgt acgatggtta ttttttattt cattcttatt
     3361 ctgatattta taggaatcag ttaccatttt ctttcttatt tttatgcaaa gaaattagta
     3421 agagcggggg tacagagagg ctatgactgg tatgaagaaa ctgggcaccg cttgatggat
     3481 cctgctgcag tcacgtcagt agaaaaaaag cgacaaaaat tagaagaaga gtgtgaaagc
     3541 ttctgggaac aaggaatacc gaaaacgatc aaaagttatg acgggttgaa actagctgga
     3601 cagatgttcc tccaaccaac tcagcagaat aaatgggtca tttgtgtaca tgattatcga
     3661 agtacaggga aaagagatat gtctcatata ggtaaaagat atgcagagaa aggattcaac
     3721 gttcttatac ccgatttacg tgcgcatgga gaaagtgaag gagaaatcat cggaatggga
     3781 tggctagacc ggctagattt aattgcatgg atccaactca tcttagatga acaaccagat
     3841 gcatccatta ttttgcacgg cagttcgatg ggcgcttcta ctattatgat ggcaagtggt
     3901 gaaaagcttc catctgcagt caaaggattt atcttagaca gcggatatgt ttctgtttat
     3961 gcggaatttc ggtatatgtt aagtaaaatc acggtctttc ctaaaaaaat gatcatgaga
     4021 tatgcgaatc actatgctca gaaatacgca ggttattctt taaagcaagc atcagctaca
     4081 agacagcttg gtagtaacca tttgcctttg ttagtcatcc atggtgaaag agatcatttt
     4141 gttcctacag aagcagcata cacgattcaa aacgctacgg caggggataa agcattactg
     4201 cttgttccag aagcagaaca tttggaagca tcgatgaaag atccgaaaac ctattggaca
     4261 gtgatttttt catttattga acaaagaata acgatggatt gattttctct tcctttttgt
     4321 aagcaacacg aggataaata attgtttata gaccatgaga ctgttaaaat aaggtaggaa
     4381 taaaaaaata tcagttattt gaggagtgcg gcatatggaa atcaaagagg aaaaaaatcg
     4441 tcttgcttta ttcaatgatg agcaacaaga aatcggagaa atgacatggt cggatgcggg
     4501 gccagacatc atgatcattg accatacatt tgtcgatcca gcatatcgtg gtcaaaaatt
     4561 agctgaaaag ctagtgtata ctggagtaga actagcaaga cgagagggga aaaagattat
     4621 cccttcatgc ccttacgcaa aaaaagagtt tgagaagaaa ccagagtatc atgacgtctt
     4681 acgccaatca taataataac agctgaaaga tttgcacttt cagctgtttt tccatttata
     4741 tagagttgtc acggagtttt atctatgata aagttaaaga gacgatatct tttgggaagg
     4801 aggctgctat atgtataatt taattttggg aatcgtgatc gttttatcga ttgttatggt
     4861 cattgcgatt atgatgcagc caagcaagca aaatagtgca gcgagtgcat ttaccggcgg
     4921 tgcggatcaa ctattcggca aacaaaaagc tcgcggcttt gaagctgtca tgcagcgatc
     4981 aactgcagtc atgggagctg tctggatgat cttattattt gtcctagcat ttttatcttc
     5041 gaagtagtcg aataagcctc tcgcacaacg gcgggcggct ttttttattg caaagagaac
     5101 gcttaagaag aagttatgaa agaaactatg gtaaaatgag gcgaaagagg tgaaacgagt
     5161 gaaacaatta ccaaaacccc tttatgcaaa acatggaaaa cgagcagttt tgctgcttca
     5221 tgcgtactca ggaagtccaa atgatgtccg gatgctcgca cggtttttag aaaaagcaga
     5281 ttatacagtc tatgcgccgc tatttaaagg acatggaacg atggagccat atgatatctt
     5341 gcaagaaaaa gcagaaagct ggtgggcaga tactaaaaaa gctatccatt ttttacagtc
     5401 tgaacagttt tctgatattg ccgtattggg attatcgatg ggtggcatct ttgctgtacg
     5461 ggcactagaa gaagaatcag taattggcgg cggttttttc tgttcgcccc tgtctcctgt
     5521 agaaacaaac gtgcctgaaa attttgaaaa atatgtacgt caagtgctga agatagcagg
     5581 caaatcagaa aaagaaatca atgaaaaagc tgtgtcttac cgctcgttag ctgaacatca
     5641 attaatggat atacaagacc aagcagcaat cgcagaaagt agactatcag atatccaaca
     5701 gccaatattt ttagctcaag ctgggaaaga tgaaatgatc gacccaaatg gtgtatttga
     5761 aacggcacgc aaattgagcc gccaacgagt gacacttcaa tggtatcctg aaagcggtca
     5821 tgtgattaca gttggcacag caagacgcga attagaaaaa gacgtgttgg aatttttaga
     5881 aaaattacct tggaatgagg aataaatatg acaaaagaaa caataaaaga gaaaattctc
     5941 tttttcatgg aaagcagtcg caaacgtagt ttttctatgg aagaaatcgc tgaaggtcta
     6001 ggctttcaaa aaagcgatga ttttaaatta ctagtacaaa cgattgctca aatggaaaga
     6061 gaacagagta tcgttttcaa taaaaaagga aaagtcaaac ttcctttaaa accgatcttg
     6121 gtcgaaggga catttcgggc aaatgaacga ggatttggat ttgtaacgat tgatcccgaa
     6181 gaagatgata tctatatccc gaaagaagcg actggctttg caatggatgg ggataccgta
     6241 gcaattgata tcatgaagcg agcaaataca gatatggatc gcggagcaga gggaaaagta
     6301 gtggagattc gagaccgagc gactactcag ttagccggag aatttgttgc ttattcagac
     6361 gaagagatac aggaaacgga tctttatggt gtggtcatcc cgaaagatag aaagcttaac
     6421 caattcaaag tgtatgcagc ggcagaggga gttcgtccag ttgacggaag tattgtattg
     6481 atcgaactga cccattaccc tgaaaaaggg tatgcaacta gtttagaagg gataatcaag
     6541 caagtgattg gtcataagaa tgaccctggc atggatatcc tctcgattgt cgtggctaac
     6601 ggtattccta caaaatttcc tgatgatgtg ttatctgagg cagatgaagt tccagaccag
     6661 atcagcgaaa aggatattgt tggacgcaga gatttaagag atcagctcat cgttacgatt
     6721 gatggagaag atgcaaaaga tctagatgat gcagtgacgg tcaaaaaatt agaaaatggt
     6781 aattattttc ttggagtaca cattgcagat gtatcttact atgtgacgca aggcagtcaa
     6841 ctggacagag aagcatacga aagaggaaca agtgtctatt tgaccgatcg agtgattccg
     6901 atgatcccac aacgtttatc caatggtatc tgttcattga atccccatgt tccacgactc
     6961 accatgagtt gtgaaatgga gatcgatcca aatggacaag ttgtctctca tgagattttt
     7021 ccaagtgtga tccaaacaac agaacggatg acctacacag ctgtcaatca aatcttagaa
     7081 gatcaagatg aagaaacgat gcaacgttat gctcagctcg tgcctatgtt ccaagaaatg
     7141 ggtgaattgc atcgaatcct tgaaatgatg cgaatcaaac gtggagcgat ttcttttgag
     7201 gatcgtgaag cgaagatcct tgttgatgct gaaggacacc caaatgatat ccagctaaga
     7261 agcagaggga taggtgaacg cttgatcgaa tcctttatgc ttgctgccaa cgaaacggta
     7321 gctgaacatt ataataaatt aaatcttccg tttatttatc gaatccatga acagccaaaa
     7381 gaagaaaaaa tgcagcgctt ctttgatttt gcttcagctt tgggcattct ggtccgagga
     7441 acgaaaggaa cgatcacacc aaaagattta cagcatgtga tcgaaggagt agaagacaaa
     7501 ccagaagctg cagttatcaa tactatgttg ctaagaagca tgcaacaagc acgctattca
     7561 gaagacaatt ttgggcatta tggcttagcg gcagattact acacacactt tacatctcct
     7621 attcgacgct atcccgatct aatcgtccat cgtctgatcc gttcttacag tgaagataaa
     7681 agtgaaagca atcaaagttc gtgggctgcg gaacttcctg aaattgcaga tcatagttct
     7741 aagatggaac gtcgtgcagt agaaacagaa cgtgaagtag attccatgaa gaaagcagaa
     7801 ttcatgatgg acaaagtggg agaagaattc gatgggatca tcagctctgt tgtgaaattc
     7861 ggcctgttta tcgaactgcc gaatacagta gaaggattga tccatatcaa tgaattgaaa
     7921 caggactact tccattttgt tgaaaatcat ttagctcttg taggtgaaag aactggtctg
     7981 acttttaaaa tcggacaaaa agtgcgcgta aaagtagtca aagctgatcc agatgaacga
     8041 gcagtggatt ttgaactcgt ttccgcagaa gaggtcactg cgttggaacg tccaaaagca
     8101 cgcaatggaa aatctggaaa acgagaagga aaacaagcag gcaaacgctc agaaaaaaat
     8161 ggcaagaaga acaaacgata tagtgatagt aagcaaacgt tcggtaagaa aaaagggaaa
     8221 aagccatttt acaaaggtgt caaaaagaag aaaaagaaaa aataaaatga gttggaggaa
     8281 acagctatgc caaaaggcga gggaaaacta attgcacaaa acaagaaagc tcgccatgat
     8341 tattcgatca tcgacacgat ggaagcaggg atggtcttgc aaggaacgga gatcaagtcg
     8401 atacgaaaca gccggatcaa tctgaaagat ggatttattc gcgtccgcaa cggggaagct
     8461 ttcttgcata atgttcatat cagtccttat gaacaaggaa atatttttaa tcatgatccg
     8521 ttgcgcacga gaaagttatt attacacaag aaacaaatcg ttcgtcttga aaacgaattg
     8581 aaaaacactg gaatcactgt tgttccttta aaagtctata ttcgtaacgg ctatgccaag
     8641 gtattgattg gtctggcaaa agggaaaaaa tcgtatgata aacgggaaga tttgaaacga
     8701 aaagatatcg atcgacaaat tgatcgaaca ttaaaaaatt tctctagata atttcattat
     8761 cctttttcgc atattcggtg cttttgcttt tacttaatga taaaatttgt tagcatttaa
     8821 tctgataaaa catgattatc acaggttttt tcttagatca ggagcaccgt gcatggggaa
     8881 aaattcgctt cgtttttgac tgaaataaaa aagtgtctaa ttttcatgaa aatgttttga
     8941 attttctgtt tcatggtggt atgataccgt gtggttagaa accgattgga aaaaaccaga
     9001 tacgcacatg aattgatttt atgtgaattt cggggaaaag aggtgaaatg gattggatga
     9061 acgctcgcta acgtttcaca ttggaccaat ttggtttgat ggtacagttt gtataatggt
     9121 gttactgacc tgtttgattg ttttcttctt agcttacttt tttacaagaa atcttaagtt
     9181 gaaaccaaca ggcaaacaaa atgcgataga atgggtcatt gattttagtc gaggaatcgt
     9241 aacagataat ctgcctagaa aagaattgag caatttccat ttgttggcat ttacattgtt
     9301 tttatttgtt tttgttgcaa acaacatagg tttagtaaca aaaatcgtct tacctaacga
     9361 aacaacactt tggaaaagcc cgacagcaga cccgtttgtt actttaactt tggcatttat
     9421 aatgatctta cttactcact tattcggggt gaaaaagtta ggcttcaaag gatatttcgt
     9481 aaattcgttc ttgaaaccct atagttttat gtttccgatg aaactgattg aagaatttac
     9541 aaacttatta acacttgctt tacgtcttta tgggaatatt tatgcggggg aagttttgct
     9601 aaccttgatt gcaaaaatga tgacaagctt aggctggttc tcattaccat tagcaattcc
     9661 attagagatg gtctggatcg cgttctcctt gtttattggg agcatccaag catttgtctt
     9721 tgtcactttg tcaatggttt atatgagcca taagattgaa gtagaagaat aatactcggt
     9781 taaaaaacaa actactattt atctatttta ggaggaaaac aattatgaat tatatcgcag
     9841 cagcaatcgc aatcatggga gcagcaatcg gagccggtta tggtaacggt caagttatct
     9901 ctaaaacaat cgaatcaatg gctcgccaac ctgaaatgtc tggtcaattc cgtacaacaa
     9961 tgtttatcgg ggtagctcta gttgaagctg ttcctatctt aggggtagtt atcgccttga
    10021 ttctagtttt tgccgtttaa ttgaatcagt attaaggcag aaacaacatc gtttgttact
    10081 gcttttttac atggaaacta gaaatactcc aaagaaagga aggctcgcct atgctgaatc
    10141 aattggcaat tgcagaagtt ggcaatgcga tgttaggtaa tatcatcgtt gtcagcggct
    10201 catttttgat actactggct ctcttgaagc actttgcttg gggaccaatc agcgatattt
    10261 tgaaaaaacg tgaagacaag atcgccaatg atttagattc tgcagaacaa tctcgcatca
    10321 actcagcgaa aatggaacaa gaacgcgaac aacaattgtt agcctctcgt tctgatgcag
    10381 ctgatatcat caaaaatgcg aaagaaagtg gagaattaag ccgccaaaat attttgaagg
    10441 atgctcaaga agaagcagct cgtctaaaaa gcaaagccca agctgatatc actgtagaac
    10501 gtgattcagc gctgaactct gtaaaagacg acgttgcaga actctctctt caaatcgcgg
    10561 aaaaaatctt gaacaaagaa ttatctccag aaatgcatga atcattaatc aatcaataca
    10621 ttgaaggtct aggttcttca aatgaaacta gataaatata cagtaggaag acgttacggg
    10681 aaagctttat ttgaactggc gatcgattca aatcaagcag aagaaatcta tcaagatctc
    10741 gtaagtttac gtcaaatcta tgaacaagta cctggattag ggaatatgtt aagtgatgtt
    10801 cgtctagaac ctcatgaaaa acgagaaatc atggacaagc ttgtcagcgg ttatgatgga
    10861 atcgttaaaa actttttaga agttgtttat gagtataacc gaatggatga ccttttgttc
    10921 atgattgaag aatatgaacg tcgatatgat gaacatcaag ggttactatt gggaagtgtc
    10981 acaacagcag tcccactttc agacgaacaa cgaatacaat tagaaaagaa tgttgcaaaa
    11041 acaatggact atcaatcagt tgaattaaaa caaatcgttg attcttctat tattggtggc
    11101 gcgattgttg aagccaacca tcgagtaatc gacggaagca ttcgcacgca attagaaaaa
    11161 atgcgtaatc aattaaacag atagtacaaa gaggtaggtg aatcgaatgg ccatcaaagc
    11221 agaagaaatt agtgccttga ttaaagaaca aattgaaaat tatcaaaacg tgctttcagt
    11281 cgaagaaatc ggtaccgtaa cttatgtagg tgacgggatc gctcgtgcac atggtttaga
    11341 aaacgcgatg agtggtgagt tgcttgaatt ttcaaacggc tcatacggaa tggcgcaaaa
    11401 cttagagtca aatgatgtag gtatcattat ccttggcgat ttcgagtcca ttcgtgaagg
    11461 agataaagta aaacgaacag gtaagatcat ggaagttcca gttggagagg ccttgatcgg
    11521 tcgggtagtc aatccgctag gtcaaccaat cgacggacta ggtgaaatcg ttactgacaa
    11581 agctcgtcca gtagaagcga tggcaccagg tgttatgcaa cgtaaatctg ttaacgaacc
    11641 aatgcaaaca gggctaaaag cgatcgacgc ccttgtgcca atcggacgcg gacaacgtga
    11701 attagtcatc ggtgaccgta aaacagggaa aacttctatt gcgattgata cgatcatcaa
    11761 ccaaaaaggt caagatatga tctgtatcta tgtagcaatc ggacaaaaag attctacagt
    11821 tcgtacacaa gttgaaacat tgaaaaaata tggcgcaatg gattacacaa tcgttgtgaa
    11881 tgccggtgcg tctcaaccag caccattact ttatatcgca ccatatgctg gtactgcaat
    11941 gggtgaagaa ttcatgtaca acggtaaaca tgtattgatc atttttgatg atctttcaaa
    12001 acaagctgtt gcttatcgtg aactttcctt gctacttcgc cgtccaccag gtcgtgaagc
    12061 ttatcctggg gatgttttct acttgcactc acgtttatta gaacgtgcag caaaattaag
    12121 tgatgatcta ggcggcggtt caatgactgc tttgccattt gttgaaacac aagctggaga
    12181 tatctctgct tatatcccaa caaacgttat ctcaatcact gacggacaaa tcttcttaga
    12241 aagcgacttg ttctacgcgg gtactcgtcc agcggttgat gccggactat ctgtctctcg
    12301 tgtagggggt tctgcgcaaa tcaaagcaat gaaaaaagtt gctgggactt tacgtctaga
    12361 cttagcaagt tatcgtgaat tagaagcatt tacacaattc ggttctgatt tggatgcggc
    12421 aacacaagca aaactaaatc gtggacgccg tacagtagaa atcttgaaac aaaaactgca
    12481 tgcaccgcta gctgttgaga aacaagtagt gattttgtat gccttgacac atggattctt
    12541 ggacagtatc cctgtagaca gtattttaga cttcgaacat gaattattcg aatatctgga
    12601 taccaatcat tcagatattt ttgaaacaat ccgtacaaca aaagatcttc cagaagaaga
    12661 aacgttgaac agtgcgattc aggaatataa agacatgttc ttagctacaa aaggaaataa
    12721 ttcctctaca gaagataaat tgaaatccat tcaaaatgca tagtgaggtg agatgaatgg
    12781 gtgcttcatt aaatgaaatc aagacacgta tcgcttcaac gaaaaaaacg agccaaatca
    12841 cgcgggcaat gcagatggtg tctgcttcta agttgacaaa atctgaagct tcttcacaga
    12901 agtttcaggt ttatgcaaca aaagtaagag aaatcgttac gcatttgact gctactcagt
    12961 taaatgatat tgcctcagaa aatcctagag gggatatcaa ttacaacagc atgctgctca
    13021 gccgtcctgt gaagaaaacc ggttatatcg tcatcactgc agatggcggt ctggtcggtg
    13081 gatataacag ttcgatattg aaacaaacga tgtctatttt agaagaagac caccaatcac
    13141 ccgatgatta cgtgatgatc gcaattggcg gaactggtgc agacttcttt aaagcacgcg
    13201 gtatcaacct agcatatgag ctgcgcaatt tatctgatca gccaagcttt gatgaagtcc
    13261 gcaaaatcgt aaatatggca acaactatgt accaaaacga agtattcgat gaattatacg
    13321 tatgttataa ccatcatatc aattcgctaa ctagtcagtt tcgtgtagaa aaaatgctgc
    13381 caatctcaga cttagatcca gaagaagcaa cgactttcga acaagaatat atttttgaac
    13441 cttcaaaaga agaaatcttg tctcagttat tgcctcagta tgctgaaagt ttgatctacg
    13501 gtgcgatcgt tgacgccaaa acagcagaac atgctgctgg tatgacagca atgaaaacag
    13561 caactgataa tgctgctaat atcattgatg agctgacggt ttcttataac cgtgcaagac
    13621 aaggggctat tacccaagaa attaccgaaa ttgttgccgg agcttcggca ctagaatagt
    13681 attgagattg gaggaaaaaa gatgagttca ggcaagattg ttcaagtaat cggtcccgtt
    13741 gtcgacgtgg aattttcttt agaccaatcc ttaccagata tcaacaacgc attagttgtt
    13801 tataaaaatg acgaaaataa atcaaaagtt gttcttgaag cagcgttaga attaggggac
    13861 ggagtgatcc ggaccattgc gatggaatca acagatggtt tacaaagagg aatggaagtc
    13921 attgatacag gcaaagcaat ctctgttcct gtaggtaaag aaacattagg tcgcgtattc
    13981 aacgtactag gagatacgat cgatttagaa acacctttcc cagaagatgc ggaaagaagc
    14041 gaaattcata aaaaagcacc agcctttgac gaattaagta caagtacaga aattttggaa
    14101 acagggatca aagttatcga tttgcttgcc ccatatttaa aaggtgggaa agtcggacta
    14161 ttcggtggtg ccggtgttgg taaaaccgta ctgatccaag aactgatcca taatatcgcc
    14221 caagaacatg gtggtatttc tgtatttacc ggtgtaggtg aacgtactcg tgaaggtaat
    14281 gacttgtatt atgaaatgaa agattcagga gttatcgaaa aaacagccat ggtgttcgga
    14341 caaatgaacg aaccaccagg tgcacgtatg cgtgttgctt tgactggttt gacgattgcg
    14401 gaatatttcc gtgatgtaga aggtcaagat gtactgttgt ttatcgacaa cattttccgt
    14461 ttcactcaag ctggatctga agtatcagcc ttgttaggac ggatgccttc tgcggttggt
    14521 tatcaaccaa cattggcaac agaaatgggt caattgcaag aacgtatcac atctacgaaa
    14581 aaaggttcga tcacatcgat ccaagcaatc tatgtgccag ccgatgacta cactgacccg
    14641 gcgccggcaa cagcattcgc ccatttggat gcgacaacca acttggaacg taaattaaca
    14701 gaacaaggga tttatccagc ggtagatcca ttggcttctt cttcaagtgc tttagcacct
    14761 gaaatcgtgg gagaagaaca ttataaagta gcaacagaag tccaacacgt attgcaacga
    14821 tatcgtgaat tacaagatat cattgctatc ttaggtatgg atgaattatc cgatcaagaa
    14881 aaagtgttag tttctcgtgc ccgcagagtc caattcttct tgtcacaaaa ctttaacgtg
    14941 gctgaacaat ttactggtct tccaggttca tatgtccctg tagaagaaac agtgaaagga
    15001 ttccgcgaaa tcttggaagg caaatacgat gatcttcctg aagaagcttt ccgaagtgtt
    15061 ggccgaatcg aagacgtcgt agaaaaagcg aaaacactag gctactagaa aggggtgccc
    15121 catggatcaa tatttaacag taaatgtggt aactcctgcc ggtttggtct atgatcacca
    15181 tgcagctatc gtcgttgcac gtacgacagc tggtgagctt gggattttgc ctaaacatgc
    15241 accaatcatc gttccattga cgattgatga agttcgtgta aaacgaacag attcagatac
    15301 ccacgtcgat tggatcgctg ttaatggcgg aatcatggaa gttcgtgata atgttgtttc
    15361 aatcgttgct gatagtgcgg aacgtgaacg tgatatcgat gtatctcgtg cggaacgtgc
    15421 aaaacaacgc gcagaacgcc aaatcgaaga agcaaaagca aaacaagata cgaacgaatt
    15481 gaaacgggca actgttgcgt tgcaccgagc aatcaatcgt atcaaagtat ctaagcactc
    15541 ataaaatgag atgcggatgt ttatccgtgt ttaagaacag taaaaagagg ttatgacaga
    15601 agtggtcagc ttcaagacat aagaaggaat ttacgaaaat tgcttctcaa atttttgtga
    15661 aatctcagct tatttttcga agaagctact tctggaacac cgtatatcag aggttgtgaa
    15721 atcagcgttt tgtcctgagt attagagaaa caaatggaaa atagttcctc atattttgcc
    15781 gttttttgag ctaataccga gggtcagatg attgaacacc gtttatttgg aataagggac
    15841 tgcgacaaga cttttgtctc agtccctttt tttgcatatt tttagcattt atttcctaaa
    15901 aaatgtaagg ggattcctat atttttaagt atacttgttt ttccttttat acattttatg
    15961 gtattatcat tttattagtt attataaaac aatcgttaga aaggacgtca ttatgcaagt
    16021 atacggaatt gatgcggtgc ttcgaatcgt gagtcatttg gcgtttatct acttagcctt
    16081 ctggtcttta cgttcgttac gcattgaaac ttttttcaga ccaatgcata atacgcaaat
    16141 tagaatggca atcgtacttt tttcaatttt tttagggtac actgcaagta attttttctt
    16201 agaagttatc gctttatgcc gaaatctttt cgttagcctg taaattttaa aaaaaggtac
    16261 tattttaaaa gcaaggatgt tataatagaa aagattttga gtaagtgtat gctcattgga
    16321 attttttgga gggaacaaca tggaagagat catcgtaaga ggtggcaatc aattaaatgg
    16381 aacagtaaga attgaaggag ctaaaaatgc tgttttgcct attttagctg ctagtttgtt
    16441 agcagaagaa ggtattacga cattagacaa cgttccgatt ctttctgatg tcttcactat
    16501 gaatcaagtg attcgtcact taaacgtaga tgtagatttt gatgaacaaa agaatcaagt
    16561 aacaatcgac gcttcaagac aattagaaat cgaagcgcct tatgagtatg ttagtcaaat
    16621 gcgtgcttca atcgttgtga tgggtccgct acttgccaga aatggacatg caaaagtagc
    16681 tatgcctggt ggatgtgcga ttggtaaacg accaatcgat ttgcatttaa aaggatttca
    16741 agctttagga gcaaaaatta ttcaaaaaaa cggctatatc gaagcaattg cggatgaatt
    16801 gatcggtaac acgatttatt tagatttccc tagtgtgggt gctactcaaa atatcatgat
    16861 ggctgccgta aaagcaaaag gaacaaccat cattgaaaac gtagctcgcg aaccagaaat
    16921 cgttgattta gcaaacattt tgaataaaat gggcgctcaa gtctatggag ctggtactga
    16981 aacaatgcgt attgaaggcg tggatcattt acatgcagtc aaccactcaa tcgtacaaga
    17041 tcgtatcgaa gcaggtacct ttatggttgc tgctgcaatg acacaaggca atgtgctgat
    17101 tgcagatgct atctctgaac ataactgccc attgatttct aaattgatcg aaatgggtgc
    17161 agaaatcatt gaagaagaag gcggagtccg tgtcatcgga ccaaaacata tcttacctac
    17221 agatgtaaaa acgatgcctc atcctggttt ccctacagat atgcaagctc aaatgacagc
    17281 tatccaatta gttgcagaag gtacaagtgt ggtgactgaa acagtgtttg aaaatcgttt
    17341 ccaacattta gaagagatgc gccgtatgaa cgctcatgtc aaaatcgacg gaaatgtagc
    17401 aatcatggat ggaaaccatg aattgcaagg tgcagaagta tatgcaacag acttgcgggc
    17461 agcagcagca ttagttttag ctggcttgaa agcaaatgga atcacacgtg tgcgtaactt
    17521 gaattatcta gaccgtggat attataattt ccatatcaaa ctacagcaat taggtgcaga
    17581 cgtcgaacgt gtagacatgg atcaaacttc tgctgaaaaa acagcacaaa cgattgctta
    17641 aggaagtggc tgaatgagta accaacgata tatcttatta actttgataa agattttagt
    17701 ggtgatctta ttgcttatcc ttctttttgt ggccggaacg atgatcggat atggtgtcat
    17761 cggtggcggc aatccattta aagtattcca gccaagtttg tggattcata ttcgagactt
    17821 ttttcattga taaataagaa tcacagtggt tctagtcgat atgaagtgag ccatgaagca
    17881 gaacatgata aaagaaaaca gaagggaacg ttgacgttag tcgcgatccc tttttttagt
    17941 aaaagaaaag aaggaatcta attgatgaag aagatattga tttatttagt tagaggatat
    18001 cagcgcttta tttcgcctgc atttccacct agctgccgtt attacccaac ctgttccaat
    18061 tatatgataa aagcaattca aacccatggt gcgctaaaag ggacggtaat ggggactgca
    18121 cggatcttac gctgtcatcc ttttgtcaaa ggcggtatcg attatgtacc attgacattc
    18181 cgattaacgc gaaataagaa agataaaaaa gaaccagatt ataaaaaggt tgtgaaaaat
    18241 acgggtagca ctgagcgata aagaaaaaga ggaaatttat tgtcaaagta acaactccgc
    18301 aactacttat atgggggaca aaaaatgatc gaagaactaa acaagaaaga tttaccatgg
    18361 tccttgttat tagatgcaga tcctgataaa gaaaaagttc aagtatatgt ttccagaggg
    18421 agtggctgga tatggaaaga aaaagaaaaa acaataggtg tactgatcta tgtggcaagg
    18481 gaaaaagaat acgaaatcgt caatgtagca gtaaccccaa cgtatcaagg aaaggggatt
    18541 ggcggaaaat tacttgagac agcttttcag aagctttcac agctagcttc aaaccaaact
    18601 cggatcatta tacgtactgg cactactagt agcgctgcgt tacacctcta tcaaaaaatg
    18661 ggctatgtgg agattggtcg agtcaaagac tattttatcc atcattaatc tgagcccatt
    18721 tttgaaaatg gagatcaatt aagggatcaa gtgattttag caattcactt acctaaaaat
    18781 agctttaact aataaacttt caattcgaga aaatgctttc aaatgctaaa tagatacatt
    18841 acaatagctt tagcaaacaa aaaggagaat atttttatgg gaatattagt ttttgatttt
    18901 ggtggatcgg ctgtcaaata tggttgttgg gatggcaaag agattaaagg taagggacaa
    18961 tttgcaacgc ctgaatcttg ggaagaaatg aaaacgcaat tatttcaagt ttataaaaaa
    19021 atactcgttt cttttgaagt cgaaggaatt ggaatcagct ctcctggagt agtgaataat
    19081 gagaaacagg tgattgaggg aatcagtgcg attccttata ttcatggatt taatattttc
    19141 cgagatttgg aaactctgtt tcaactccca gtaacgattg aaaatgacgc caactgtgcc
    19201 ggaatggctg aattttatga aggtgctgcc cgtgattatc aagatgttgc ttttgttgtg
    19261 gcaggaactg ggattggcgg ggcgttgttc acgaaaggac aaataaataa aggggcacat
    19321 ctttacggtg gagaatttgg gttgatgttc ttagatggcg ataagacatt cagtaaactt
    19381 ggtacagcgg tacagatggc ttggcgttat tgtgaacgca aaggtctcga taaaaatgct
    19441 tataccggaa aagatgtctt tgaattagca gaaactggag atgcaatagc aaaagaagaa
    19501 gttgagagtt tttatacgta tcttacaaag ggattattca gtattcaatt ttcgtttgat
    19561 ccagaagtga tcgtattagg cggcggggtt tctgcaaaag aagggctcat tgatgagatc
    19621 aaaagccgaa tgaagaagct gacagaacaa ttcgatctgc atgatttcga accgcagatt
    19681 ttattatgtg agtacagaaa cgatgctaat cttgtaggtg cagcagcaaa ctatctcgct
    19741 gtacgtcaag gagagaatta agagctttag agaaggtgca gcttgcataa aagaagagaa
    19801 tgaaatgaat aggagatttt tacctaagga atgttttatt tgctgcagta tgataaaata
    19861 tctgagaggt gaaaatgatg tcaaaaaaaa ataaagatat tgaagtgcgt atagaagaag
    19921 tgaaaaaaga tatcaaaggt aagaattatg aagtcactca gttatttata gggaaaaaaa
    19981 tgattggtga gatcttagcc tatgggccaa aagaatatga aattttcttt ggtgaagaag
    20041 attttggaaa agaaaaaagt cttgaaaatg cgatagaaac agtgattcga cactggaatc
    20101 tgcacgaata aaaaaatatc aaaaaaactt tcaataaagg gttgcaaaaa tctggaaaat
    20161 taggtattat aactaagtca ggttgataca aacctttcgg aggagtagcg aagtggctaa
    20221 acgcgacgga ctgtaaatcc gttccttagg gttcagtggt tcgaatccac tctcctccat
    20281 ttcattgggg tatagccaag cggtaaggca agggactttg actccctcat gcgttggttc
    20341 gaatccagct accccagtat ac
//
LOCUS       DAZKCH010000053        19905 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000053 DAZKCH010000000
VERSION     DAZKCH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.053"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            337..654
                     /locus_tag="ACG84X_001885"
     CDS             337..654
                     /locus_tag="ACG84X_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFP9127733.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(858..1223)
                     /locus_tag="ACG84X_001886"
     CDS             complement(858..1223)
                     /locus_tag="ACG84X_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127734.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1431..1913
                     /locus_tag="ACG84X_001887"
     CDS             1431..1913
                     /locus_tag="ACG84X_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127735.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2110..3000
                     /locus_tag="ACG84X_001888"
     CDS             2110..3000
                     /locus_tag="ACG84X_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFP9127736.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            3325..5796
                     /locus_tag="ACG84X_001889"
     CDS             3325..5796
                     /locus_tag="ACG84X_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFP9127737.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(5899..7635)
                     /locus_tag="ACG84X_001890"
     CDS             complement(5899..7635)
                     /locus_tag="ACG84X_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9127738.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(7632..8336)
                     /locus_tag="ACG84X_001891"
     CDS             complement(7632..8336)
                     /locus_tag="ACG84X_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9127739.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            8467..8970
                     /locus_tag="ACG84X_001892"
     CDS             8467..8970
                     /locus_tag="ACG84X_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFP9127740.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            8930..9268
                     /locus_tag="ACG84X_001893"
     CDS             8930..9268
                     /locus_tag="ACG84X_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFP9127741.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            9289..10707
                     /gene="ffh"
                     /locus_tag="ACG84X_001894"
     CDS             9289..10707
                     /gene="ffh"
                     /locus_tag="ACG84X_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFP9127742.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10819..11397
                     /locus_tag="ACG84X_001895"
     CDS             10819..11397
                     /locus_tag="ACG84X_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFP9127743.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            11401..11922
                     /locus_tag="ACG84X_001896"
     CDS             11401..11922
                     /locus_tag="ACG84X_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFP9127744.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(12001..12555)
                     /locus_tag="ACG84X_001897"
     CDS             complement(12001..12555)
                     /locus_tag="ACG84X_001897"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFP9127745.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            12808..13083
                     /gene="rpsP"
                     /locus_tag="ACG84X_001898"
     CDS             12808..13083
                     /gene="rpsP"
                     /locus_tag="ACG84X_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFP9127746.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            13095..13346
                     /locus_tag="ACG84X_001899"
     CDS             13095..13346
                     /locus_tag="ACG84X_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFP9127747.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            13471..14262
                     /locus_tag="ACG84X_001900"
     CDS             13471..14262
                     /locus_tag="ACG84X_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127748.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            14432..14953
                     /gene="rimM"
                     /locus_tag="ACG84X_001901"
     CDS             14432..14953
                     /gene="rimM"
                     /locus_tag="ACG84X_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFP9127749.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14943..15704
                     /gene="trmD"
                     /locus_tag="ACG84X_001902"
     CDS             14943..15704
                     /gene="trmD"
                     /locus_tag="ACG84X_001902"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFP9127750.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15840..16187
                     /gene="rplS"
                     /locus_tag="ACG84X_001903"
     CDS             15840..16187
                     /gene="rplS"
                     /locus_tag="ACG84X_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFP9127751.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(16319..17455)
                     /locus_tag="ACG84X_001904"
     CDS             complement(16319..17455)
                     /locus_tag="ACG84X_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9127752.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLHKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKIPETYIVSGINTIDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PIDEVVIDYKRESKTIKIKDKFLEDDEYNRLVDFTTSHNKRYSLLFQWLYLTGMRSGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPNGQFLFQTTKGTPFQLTAINTYLRSHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(17571..18137)
                     /locus_tag="ACG84X_001905"
     CDS             complement(17571..18137)
                     /locus_tag="ACG84X_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HFP9127753.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWLLAVVVVFIAIGSQGGSD
                     DAKNTVAETTKESVTEVSSAESVAESTVVEEETETTETTIEEVTQEESVPREYRNALS
                     KAESYLGWAGMSEQGLREQLEFEEYPSDAIDYALANVDVDYNEQALAKAESYDDWASM
                     SDSQLYDQLIFEGFTNEQAQYALDNLPQ"
     gene            complement(18273..18926)
                     /locus_tag="ACG84X_001906"
     CDS             complement(18273..18926)
                     /locus_tag="ACG84X_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127754.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDTTSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(18976..19404)
                     /locus_tag="ACG84X_001907"
     CDS             complement(18976..19404)
                     /locus_tag="ACG84X_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFP9127755.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRDRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIEELKNLYGLPESAYRFLI"
     gene            complement(19409..19783)
                     /locus_tag="ACG84X_001908"
     CDS             complement(19409..19783)
                     /locus_tag="ACG84X_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9127756.1"
                     /translation="MSLVTKIKELADEKHVTIAEVERQVGISNGQIRRWDKASPKSEN
                     LKKVADYFGVTTDYLLGNNNVPKWATKEEVVELDKLLDSNVNMSYGGETLTPEQIQRV
                     KDILIATFWDIVKEDKEKGKKM"
BASE COUNT         6436 a         3541 c         3885 g         6043 t
ORIGIN      
        1 ggatttagag taattaatta gatgtttatt ttataggact gatattatag attacaaata
       61 gtatcgtatt tcgcaatctt aaaattatct tcttactatg aataagataa taaaatttgt
      121 atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca acgaaagtat
      181 actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg ctgctaaaat
      241 atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct aaacataatt
      301 ttttcggtat ttaatattta attaggaggg aatattttgc ttttttatag taattttatc
      361 ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag tagaaatgca
      421 agtataggtt ttagaactaa acgaagtctg tcttctaaaa aaaattgggt atactcacaa
      481 actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact ttattctttg
      541 aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat tattgctgca
      601 attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa atagaaaaac
      661 tagtgatagt tttggtgata gtgatattaa aaatcagaaa agatagaaaa agcaggagat
      721 agataaaatg ctgatatttc agcatttttt aagagtataa aagagaaaaa aagtaataaa
      781 tgtatacatg atataagaaa aacatatatg tataaaaaga agaaagtagc ttctctttgt
      841 acatatatgg tttgttttta tggatgccga gcttttttat aagataaggc taccgcccat
      901 aacgacccaa ggatttgtgg aactaagtaa atacctgcaa gaagcaagat cagctgggtc
      961 ggttttaaag gatgatagaa gtaacgccat tcagtaaaat tggcgcaaaa taaataggaa
     1021 gtgacagtag atataatatt ggcaatgaat aaagatataa tacgcctgtt cctttgaaaa
     1081 taatatccag caaaaagaga taaaaatatc aatgtgatga acccgcttac ggaatgataa
     1141 cgaaaatcaa gcagtaaggc gaaatgcaca taaggaacaa aagataaaag caacggaagg
     1201 tttttccagc aagtttttat catctttcat caccacctaa caagtgttat tattttgtta
     1261 gttttattgt aaattgaatc ctgcaataat caattacttt ttcattattt ctagattaaa
     1321 tgaataaact ctcatgccat tatctctaaa aaaaaagttt ttccccctaa tttttttaga
     1381 tagaaaattg tatagtatga tgagagaaaa agtagtttgg gggaacgtta atgagaagaa
     1441 aagcagtaat cgatcggctt tatttatttt tttggttttt tcctatcgtt ttgctacctt
     1501 ttacatgggt aaatgctgtt gtacaaggtg cggagatatt aggcctgatc caaggaagcg
     1561 gatttgtggt ttctaggaat tttccagctt tgactgtttt ctatttagtg ataagtgtag
     1621 gtctcttatt accaaaatct ctgatcaatc actacaattg gcagctgctt tacttttctt
     1681 gcttattagt atttacatct atgttttctt tgctgcctcg cttgattatc ggccctaatg
     1741 gtttgagcga gagtggattg aaggattcag cttattcctc catgtatttc ttgacgatca
     1801 aaccatggtt ctatttagta attgcctcat ttattcttgc aacatttttt tacttctgga
     1861 cagaaatcag gataaaaagt gaacgatctg tatctataaa aaataactat tgatggtgga
     1921 tcatcagtaa aaaagcatat gagctgcgta aaatgcatgt ttctcatatg ctttttttat
     1981 tattatgtaa agaatgcgaa aaacgtttac atgattttta cataacttaa ctatattttt
     2041 acagcaacca tacgagggat ttacagtcga ctgataaact ttagttgtaa ataagaaagg
     2101 agcaataaaa tgaaaaaagt attgtttact ctaggtatga tgggaattct tttagccgga
     2161 tgcggctcag gatcaggaaa tacagatggc tctgccacac aaaataattc aagtgactca
     2221 aatgaacaag taaaaatcgt tgcggtaggt tcgacagcat tacagccgtt agtcgatgca
     2281 gcacaagaaa gctttgtaca agaaaatcca aattatcaaa tctctgtaca aggaggagga
     2341 agcggaactg gtttgagcca agtcgaagct ggagcagtta ctatcggaaa ctctgatgta
     2401 tttgcagaag aaagagacgg agttgatgct tcaaaattag tggatcataa agtagcagtg
     2461 gtcgggatgg cgccaatcgt caataaagat acagatgtca aagatatcac caaacaggaa
     2521 ttgattgata tctttacagg aaaaatcact aactggaagg aagttggcgg gaaagatcaa
     2581 aaaatcaacg tcgtgaaccg tgcaaacggc agcggtaccc gcgcgacatt cgaaaaatgg
     2641 ggactggatg gtgctacccc tgtgcagtcc caagaacaag attcatcagg aacagttcgg
     2701 cagctggtaa gtcaaacacc aggagcaatc agctatttag ctttctcata tctcgatgat
     2761 tccacacaag cactaagtat cgacggtgta gaaccaaaag aagagaatgt agcagataac
     2821 agctggggaa tctggtcata tgaacatatg tacacgaacg gaaaaccttc ccctgaagtc
     2881 caaaaattct tagactacat gatgacagaa gaaatccaag aaggacctgt caaagaattg
     2941 ggctatttac caatcacaat gatggaagta gaacgtgatc acgaaggaaa tatcaaataa
     3001 ctagcagata aacatgccac ggtagtcgtt actattaagg aaaaatcaac tatgtttccc
     3061 acatatacat ttttccttta attgtgaaaa atagttcctc atattttgcc gttttttgag
     3121 ctaataccga gggtcagctg attaaacacc gtttattcga aaaaaagagc tacgacatag
     3181 aactgtcgta gctctttttt tgctatatga caggaatgaa aggtgtttgc aagcttaatg
     3241 tgaggaacac tttccatatc tgttctatac tggataggag aagtttggaa atatccagaa
     3301 aacgaaatca atcgaggtag ccacatgaag aataaatgga taaatcgaag taaaaaaaag
     3361 aaagtaacac aaagatcatc agataaagtc atccgtcttt ttccatcgta taaagaagga
     3421 ttaacggcag atcaagtcaa ggaacgaata gaaaaaggtg cagcaaataa ttcagtcgat
     3481 cccacattca aaacaaatca gcaaatcgta ttggaaaaca tatttacgta tttcaatttg
     3541 atctttctta tcttagccat tttgctttgt ttagtagaat cctataagaa cttgactttt
     3601 ttaccagtta tcatagccaa tacaggaatc gccatttttc aggaaattcg atccaaaaag
     3661 atcttggacg aactaaatgt tttaaataca gcaaaagtca atgtcatacg ggacgggata
     3721 gaacaaacaa tagatataga agaccttgta atagatgaca ttgttatttt agagactgga
     3781 catcaaattc cagcagatgc agaggtcgtg gaaggaaaac tgcaagttaa tgaggcttta
     3841 ttgacaggcg aagcagatga aataaccaaa gaaataggcg atccattaat gtccggcagt
     3901 ttcattgttt ccggaaaagc ttacgcccga ttagacaaag ttggagcaga ttcgtatatt
     3961 tcccagctga cagtcaaagc caagacaatg ggagaaggag aacagtcgga gatgattgct
     4021 tctcttaatc aattgatcaa atggattggg atcatcatta ttcctatcgg tatcctgctt
     4081 ttttctcaaa gttacttttt taatggaaac acgatcaaag aaagtgtcgt tgcaatggaa
     4141 gcagcattga tcggtatgat acctgaagga ctgtacttgc tgacgacgat tgcattagca
     4201 ttaagtgcga ctaaactagc aaagcaaaga gttcttttac acaatatgaa aagcattgag
     4261 acattggcaa gggtaaatgt cctttgtgta gataaaacag gaacgatcac agaaaataaa
     4321 atgtctgttc aaaaagtgat cgtctctaaa aaacaagaaa taatcagtca gtcagatcaa
     4381 ttggaagcat gcattgctga ctatgcaaaa gcgatggcag gagacaatgc aacaatggaa
     4441 gctgttaaag catattttac aaaaaccact gatcaatcct atcaccatgt tattcctttt
     4501 tcttctgtcc aaaaattcag cagtgtagcg ttggcagaca aggtgtatgt tttaggagcg
     4561 cccgaaatgg ttttgcgcga tcaattgccg gaatatgcgg aagagtttgt ttctttcgct
     4621 gaaaaaggct atcgcgtgtt ggtctttggt gtgtacgatg ggattcttga agaaccagta
     4681 ttgacagaag cagtcacacc attaggctat attctgattg ctaatcctat cagaaaagaa
     4741 gcaagagcca catttgatta cttcaaaaaa cagcaagtag ccatcaaagt gatttctgga
     4801 gataatccgc tcaccgtatc caatgtagct gtccaagcag ggatttcaca tgctgatcag
     4861 tacgttgatg catctaaatt atcagaagaa gaatatgaag cagctgtcga aaaatataca
     4921 gtttttggac gcgtcaagcc agaacaaaag aaaatcttcg ttcaattgat aaagcgtaac
     4981 aatacagtag ctatgacagg tgatggcgtg aatgatattc tagccatgaa agaagcagac
     5041 tgcagtatag cgatggcttc cggaaatgaa gccgccatgc aggcctcaca agtggtctta
     5101 cttgattctg acttttcacg catgccagaa gttgttgcag aaggacggcg cgttgtgaac
     5161 aatattgagc gatcagccag cttgttttta gtgaagaata ttttctcctt tttgctctca
     5221 ctgttttcag tgatctttgc tctgacctat cctttagaac catcacaaat cacattgatt
     5281 agtttgttta ctatcggact tccatctttc ttgcttgctc tagaagaaaa caaaaagcga
     5341 atcagaggga aattcatcat gaatgtgatg gaaaaagctg tgccaggtgg actaacagat
     5401 atgatcgtag tcggtgcgtt ggtgatctgc ggggtgactt tgaatctaaa taaaacagat
     5461 gtttctacag catctaccat gcttttgatt gcagtagggt tcctcgttct ctataaaatc
     5521 tgttcaccgc tgaataaatt cagaagtcag atcattcttt tctgtgctag cggtaacttt
     5581 ttttcggtca tctttttgca taagctgttt tcaatcaccg gtatctcagc tgtatcactt
     5641 ttgctgttga gcattctatt tttctcggca gattcgattt ttaggcattt gaccacattg
     5701 gtagaatatt tgtttgaacg taaaaatgaa aaagagcaaa agccgtttag tcgcgtagct
     5761 aaaaaatttc tatcgatatt taaacgagaa aattgacgaa aagtatctca aaaaagagta
     5821 aaaaagaaca accactcgtg tatctttcga agcaggatga gtcatccaac tttaaaacgc
     5881 acgagcagtt gctctttttt acattttcgg aatggtaacg gtgaaagtcg aacctgttcc
     5941 aagatgactg tctacagtaa tcgtaccatt aaggagttgc acgtagtctt ttacaatcgc
     6001 taaccctaat ccggtcccgc ctgaatgtcg gcttcgcgcc ttgtctacgc ggtaaaaacg
     6061 ctcaaagatc cgttcctgat cctcaatgtc gatacctata ccaaagtctt ggacagaaaa
     6121 cgatagatca tctgttgcct gatagcggat aataatctcg ctgtcgcttt ttgaatattg
     6181 gacagcattt tcaatcagat ttttgataat tggataaagg atatctgttt tagtagtaaa
     6241 tggttcgttc tttccaatca atcgaatcgt caaccgtttc ttttcgatga ttggctgata
     6301 attttgaacg atttgctgga aataaggttc tgtataaatt gtctggatct cgtaagaatt
     6361 ctcgccatct tttgacagct ggatgatttc ccgaatcagt ttatctaacc ggatcgcatc
     6421 tttttgcatg atctcaagaa aagaagtcag agtttgcggg tcatcttttg caccatccag
     6481 taaagtctcg gtaaaaccaa tcagtgaagt cacaggagtt tttaattcgt gagagacgtt
     6541 gccaacgaaa tccttttgta gcttttctaa acgtcgcact ttcgttaagt catacgccac
     6601 ccctagaatc tgtccggtac cttctgaatt agtaaagtag cgcaaactca agtctaatgt
     6661 ctgccgacct tctgtaaggg tgatctcctg atggatcagc ggatgctcag gagtcacttg
     6721 atgaatcagc tgaatgagtt ttggctcttg aatgacttct gtgtaccgct gttcaggttg
     6781 atagcttacc acgtttaaat gtagctgcat ctttggatta agcagtagta aacgagaatc
     6841 agcatcatca atcaggaata cgccaatcat cagttcgttc agtaacgtat ataattgctc
     6901 ttctgtggta gtacacgccc gatacatctt actcatttgt tcgctcaacg cattaatcgt
     6961 ctgatacaat tcttcccatt gatcgggtgt ttgcatgatt acttccgcct gattaggatt
     7021 ttgcaccatt ttttttagta cgggcagcac ggttttcaat ggctggtttt tttgatagat
     7081 cagataatag atcattcctg caagaacaag gaagaaagac agaaagaaga aaaagaccca
     7141 acggcgaaaa ctctcagttc tcggtaaaaa accgcttgtc ggttctgcga tacgtaaaat
     7201 ggcttctaac tggccacttt ttttgactgg taatgcgaca tataaaagat cctcattcaa
     7261 agtagtactt ttgcgcaaag cgctacctag gttcccacca ttcaatacgg ctttgatttc
     7321 gggacgggag tttcgctgtt cattcaatgt ttcattgttt gtgtcaaata agatctttcc
     7381 agtagcatcc attaaagtaa tccgttcgtt cgactgatgg acgaattctt ccaaagcagt
     7441 tttgttttgc gctgcttgga ggttttcgac atctaattgc cggatcagca gttgtgcttt
     7501 ttttgtcagg tagctttctt gctgttccac gatctgctgt tgaaaataat gggaaatcaa
     7561 ttgccagcca ccaaaaaaca aactaactaa aagaataaga aagaagagac gttcataaat
     7621 ttttttccat ttcatcgttt tggttcctga aacttatagc caaatcctct aatagtcacc
     7681 aagtactttg gatgttttgg atctcgctcg attttttctc gcaaatgact aacgtgtaca
     7741 tctacgattc ggctttgtcc tgcgaagtca aaattccaaa tgcggtctag caatgtgtct
     7801 cggtcgatca cacggtcttt tcgtttcatg aaataaacaa gtaattcaaa ttctttcggt
     7861 gttagttcaa tcagatggtc gtctacggtc acttgataat tggtcaaatc agcagtgatt
     7921 tgtccaatcg atagatattc aggctcagct tcatcttttg attgcttacg aggttcaatc
     7981 cgtctgaata ttgctttcat acgggctaat acttcgcgag gactaaatgg tttggtcaaa
     8041 tagtcgtcag cacctatttc taggccaatg atccgatcca cttggtcatc tttagccgtc
     8101 agcatcaaaa tcggtgtttc atttttttct tgacgcagcc gctgagtgat ctccatgcca
     8161 tccatcgttg gaagcatcac atctaaaatg atgaaatcaa atgattgttc taatgctaat
     8221 tctaatcctt cgcctccatc tgtggcactg gttaccttgt agccttcttt ttccaaattg
     8281 aacgtcaaga gcgttacaat agaaggttca tcatcaacaa ctagtatttt tttcattcaa
     8341 atctccttta aataggtttc attctgttta tattttagca tagaatcagt acaaagggct
     8401 attttacaaa agaaataaat ggtataatag gaaggcactt tgctgaatag aaaggaagag
     8461 cagtcaatga ttggaatcag tgcatgttta ggcggtctgg cctgtcgcta tgatggacag
     8521 aaaaaagaag taccagaatt gatggaacta gttgaaactg gagaagctgt catggtctgt
     8581 ccagaagtga tcggcggatt accaattcct agagatcccg ctgaaatcat tggtggaaat
     8641 ggattcgatg tgtggaaaga tcaagcaaaa gtatggacga caagcggcga agatgtaacg
     8701 gaagcgtaca aaaatggcgc gatcaaagcc tatcaaaaat tgcaggaaaa acacattgat
     8761 ctagtcatca tgaaggaaaa aagcccttca tgcggaaccc attcgattta tgacggaagt
     8821 ttttccggaa taaaaaaaaa tggtgccgga gtggctactg cttattttat tcagcaaaaa
     8881 atgactgtgc tctctgatga agaatggctg aaaactagag gtgagcagaa tggaaatcga
     8941 aaagaccaat cgaatgaacg cgctctttga attttattcg accttattga cagaaaaaca
     9001 aatgaactac atggaattat attatgcaga tgatttttca ttaggtgaga tcgcggaaga
     9061 atacgaagta agccgacaag cagtatatga caatatcaag cggacaagca agatcttgga
     9121 ggattatgaa aaaaaactcc atcttttttc taattatatt gttcgagaac aggtattgga
     9181 aaatatgact gcatatatta cagataagta cccggaagat aaaaaactac ttgaatatgt
     9241 acagcaaatt caagcaatcg aagaataaat aaaaggaatg aagaaaatat ggcatttgaa
     9301 agcttaactg aacgtctcca gcaggcgatg ggaaaaataa gaaaaaaagg aaaagtatca
     9361 gaagctgacg taaaagaaat gatgcgggaa atccgccttg ccttactaga agccgatgtt
     9421 aacttgcaag tagtcaaaga ttttactaag cgcgtacgcg aacgtgcggt aggggcagaa
     9481 gtgctggaaa gtttatcacc tgcacaacaa atcgtaaaaa tcgttgatga agaattgacg
     9541 atcacacttg gttctgaaac agcagagtta aataaatcac caaaaatacc aactgttatc
     9601 atgatggctg gtcttcaagg ggcaggtaaa acgaccttta ctggtaaatt agccaattat
     9661 ttaaagaaaa atgaaaatgc tcgtccgctc ctaatcgcag gggacgtata tcgaccagct
     9721 gcgatcgacc aattgaaagt attaggtcaa cagctagacg ttcctgtatt tgatatggga
     9781 actgaagtca gcccggtaga gatcgtccgt caagggatgg agttagcaaa agaaaagaaa
     9841 aacgactatg tattgatcga tacggcagga cgtctgcata tcgatgaaac attgatggat
     9901 gagttgaaac aaatcaaaga attgacgcaa ccaaatgaga ttttgcttgt tgtcgatgcc
     9961 atgactggtc aagatgccgt caacgtagct gatagcttca accagcaatt aggtattaca
    10021 ggggtcgtca tcactaaact tgatggggat actcgaggcg gggcagcact atcgatccgc
    10081 tcagtgacag gcgcaccaat caaattcatc ggttctggtg aaaaattgac tgacttagaa
    10141 gtattccacc cagatcgtat ggctagccgt atccttggta tgggggatat gctgacattg
    10201 attgaaaaag cgcagcaaga ctacgacgag aaaaaagcgg aagaacttgc acagaaaatg
    10261 cgggaaaatt cattcgattt caatgacttt attgaacagc ttgatcaagt gatgggtatg
    10321 ggcccactgg aagatctaat caaaatgatc ccaggaatga atcaagtccc tggaatcgaa
    10381 aacgtcaagg tagatccaaa agatgttgaa cgcaaaaaag cgatggttta ttctatgacg
    10441 ccagcagaaa gagcaaatcc tgatctgttg aacccaagcc gtcgtcgccg aattgctgcc
    10501 ggttctggaa acagtgttgt tgaagtgaat cgaatgatca aacaattcaa ggaatcaaga
    10561 aaaatgatgc agcaaatgtc caaaggggat atgaacatcc caggtatgga ccaaatgttt
    10621 ggttcaggcg tcaaaggaaa actaggcaaa atggcgatga atcgaatgat caagaaaaat
    10681 aagaagaaaa agaaaaaacg gaaataagat gaaaaaaaca gcttcggtac agactgaaaa
    10741 tgtctactgc cggagctttt ctatcagcaa tttttattct ttactaatac aattactcta
    10801 aacgaagagg tggcacagat gagatgtccg tggagtgaac aaacagaaag tatgcggcaa
    10861 tatcatgata ctgtctgggg tgttcctgaa tatgatgacc aaaagctgtt ccgaaaattg
    10921 atgcttgata ttaatcaagc cggattgagc tggcagacga ttttaaataa aagtgaagca
    10981 ttcgatgaag catatgatcg attcgatatc aaaaaagtcg caaattatgg agaaacaaaa
    11041 atcagtgaac taatggaaaa caaaggaatt attcgtaacc gaagaaaaat cgaagcagcc
    11101 gtccaaaacg ccaaagcagt cttgaaaatt caagaagaaa tcggcagttt ttcagagtat
    11161 ctttggtcgt tttctaatgg aaaaatcgtt gattcttctt atcattcaca agaagaagtc
    11221 ccaacaacaa gtcctctttc agatgaatta gcaaaagatc taaagaaaag aggatttaaa
    11281 tttatcggaa gcacaacaat ctatgctttt ttagaagctg tcgggatcat caatgatcac
    11341 cttgacagtt gtttccgcaa agaagaggtc gtacgtatcg gcagaaaggg cgaataaagc
    11401 atgcgaaaaa tcatatttta tggtgctata agtttagatg gctatttggc aacgaaaacg
    11461 gatgatcttc aatggctttt tgacactcca acaggtaagc aaactactta tgaagctttt
    11521 tatgaaacaa tcgatacgac catcatgggc agaaaaactt atcaggaagc aaaaaaatat
    11581 ttggagaccg aagcaattta tccagagaaa aagaatttcg ttttttccac ccacgcacaa
    11641 ttacaattgc cagatgctga ggtcgtaaac gaagatcctg ttgcttttct aaaaaatcta
    11701 caaatgacag aaggaaaaga tatctgggtt gtgggtggcg gtcgattgat caaaccgcta
    11761 ttggaacatc aaatgattga tgaatggtat atccagatta cccctgtatt attaggggac
    11821 gggattcctt tattccaaaa aggaacatat gaagcgcgtt ttgaaatgct agacacgaca
    11881 cgattcggtg aatttatcga attgcattat gtacgaaagt agaagtaaat aaaataaaaa
    11941 aggcaactat atgcagaaat gtcctgtaca tagttgcctt ttttattacc gttatgcttt
    12001 ttactctgtt aatttgttag aaaaatctag atacgcatct aaaatcgttt ggaagaaact
    12061 taatgttcct tcaacgatat taccattttc atcaattaga ttcgcaacgt ttccgatata
    12121 tgcttccggt tgctgcaagg ttggcacatt caaaaagaca agtgattggc gtagatggtg
    12181 gtttgcgcca aagccgccga tcccacctgg tgatgcagta acgactaaac ctggtttatg
    12241 atcccaaaca ctgtgtccat aaggtcttga gcctacatct aaagcatttt tcaatactgc
    12301 tggcacagaa cggttgtatt caggagtaac gaaaacgaca ccgtctagtc ccctcacttc
    12361 ctcacgaaaa cgagtccatt cagcaggagc ctgttctgga gtttcgagat cctcattgta
    12421 aaatggcaga tcatcgattt ttacaaatac actttcgtac ccttcaggaa gcaatttcgc
    12481 aaaagcttct gctacttttt tgttgtaaga atcttttctt aaactaccaa taaaaaatcc
    12541 aatttttttt gtcatacgat ttttcctcct tcaaactatc tataataatc ttacaaaaga
    12601 taagtaactg gagcaaataa aaacacttac tgacaaaagc tacatagaag atagattact
    12661 tatttttaac aaaaaagaag tctaaaatct tctattttct aaaaaaaatc gaatttaatc
    12721 aagctgtaaa gaaaaaaagc tttacagggt aaaaaaaaac tgttacacta catcttgtga
    12781 ataaaacaat ggaggtggaa ataaataatg gcagttaaaa tccgtttaaa acgtatgggt
    12841 tctaaaaaga gtccgtttta ccgtatcgtc gtagctgatt cacgttctcc tcgtgatgga
    12901 cgtttcatcg aaactgtagg tacttacaat cctttgaaag accctgcaga agtagtttta
    12961 aaagaagact tagttcttga ctggttatca aaaggtgcac aaccttctga cactgtacgt
    13021 aacatccttt caaaagaagg cgttatgcaa aaacaccacg aagctaaatt ctcaaagaaa
    13081 taaggtgacc ggatatgaaa gatttaagcg acttagtctt aacaatcgtt cgtccgctag
    13141 tcacttatcc tgatcaagtc aagttagacg tcgtagagtc gaaagacttt tacgagtaca
    13201 atctaacagt ggctcctgaa gatattggcc gtatcattgg aaaacaaggg cgtgttgcta
    13261 aagcaatccg cacaatcgtt tacggtgttc ggatcaatgc accgaaaaaa gtgcgtttga
    13321 atatcatcga tgataaggaa aagtaaataa acgtgctgta ctcgaatttt cgagtgcagc
    13381 ttttttgttt tttttattaa ttgaagaaat gattatttgg caaaacaagc aagaaagcgt
    13441 atccttatag gaggagggag tgaacagcca atgagaaaga aaatgttatt tattccattt
    13501 gctctattgt taagcgcttg tagttcggtt actcaagaat cagacaatac acatctatca
    13561 agcagtatat ctgaaactgt taccagtcca gaaaaaagta gtaccaaaac ggcttccacc
    13621 actgaacaaa caatggctac ctcaaataat gagaaaaaga ctgctttaga ccagttgaaa
    13681 gaacaacagc caaatgttcc catgcctcta gatgtaccag tctcttcagg ctatctcaat
    13741 atcgcagcga cacatacaaa gcaaggttat tctattttat attacagaac agatcgtccc
    13801 ctcgggttga atgctgacga attgaatcaa gaaacgccta ttgcaaccta tctatatcaa
    13861 tatgggtttg cttctagtca agaaacaatc caagttttgc agccatttga gatcgacaca
    13921 aatggtcagc aagtggactt aggttctcga atcacagggt atcagcaagg tgcagcaggt
    13981 tcaagttttc ttgaatggca agaaggaaac tggcgtattc gaatccgtgg gaataatata
    14041 gaaggccaag atcccttact attagctaaa gaaatcgtag cttatttgga agaaaacagt
    14101 ctaccagcac ctgaacaatt tggtaaaatt actgttgata tgggtgatac gacgaatcga
    14161 gccgtagaag taagctggca agaaccgaaa aatgcctata cgatcactca tcaagatcct
    14221 atgtctgcgt tgaagatggc agtttctatg aagaggttgt gaaatcagcg cgctgatctg
    14281 agcccatcat ttaactccaa gtcacaggaa gtaatcaaaa atagcacgcc gcatttttgc
    14341 ataattttgg cttaatacct taaaagaaaa ctagaattgc ctcttcacac atgctaaaat
    14401 aaaacagaca aaaaagaaat ggggatataa gttgactgaa tacttgaatg taggaaaaat
    14461 cgtaaacaca caaggtatca aaggcgaagt ccgtgttatc tcaacaacgg atttcccaga
    14521 agaacgttac aaaaaaggaa cggtgctaac actattccaa gacggaaaag cacctgtgga
    14581 attaacagtc aaaagtcatc gcaaacataa aaattttgac ttattgagtt ttgaaggaca
    14641 tccttctatc aatgatgtgg aaaaatatcg ggatggcata ttaaaagtgt caaaagacaa
    14701 ctctgtagat ctagctgaaa atgaattcta ttaccatgag atcatcggtc tgcatgtatt
    14761 agaagatgga actgagttag gtaaagtaaa agaaatcttg tcaccaggtg ccaatgatgt
    14821 ttgggtcgtt caacgtccga aaaaagctga tatattgctt ccatatatcg cttctgtcgt
    14881 caaagaagtc gatttagaag ctggagtggt ccgtgtagaa attccagaag gactgattga
    14941 cgatgaagat tgatgtattg actttatttc caagaatgtt tgaaggtcct atgggggaat
    15001 ccatcatcgg taaggctgta gataaaggat tattagatat caatatctct aacttccgcg
    15061 attattcaga taacaaacat cagacagtag atgattatcc atacggcggt ggagcaggta
    15121 tgctgctcaa agtccagccc atctatgata acatccaagc cattgaaaaa gctgcaccgg
    15181 atgtcaaaaa aagagtaatt cttcttgacc cagctggtaa acgattcgat cagaaaatgg
    15241 cagaagaatt ttcacaagaa gaacacttag tattcatttg tggtcattat gagggatatg
    15301 atgaacgtat ccgcacatta gtgacagatg aagtttcctt aggagattat gtccttactg
    15361 ggggagaatt aggtgcgatg gtcatgatcg atgcaacagt tcggcttttg ccagatgtgt
    15421 tagggaatca gacttcagct caaacggatt cttattcaac cggtttattg gaacatcccc
    15481 aatatactcg cccggcagaa tataaaggga tgaaagtacc agaagtattg acaaatggaa
    15541 atcataaatt gattgaagaa tggcaattaa aagaatcact aagaaggacc tatcaacgtc
    15601 ggcctgatct tttggaaaca cttgaatgga cacctcaaat gacgaaattt ttagaagaaa
    15661 tcaagaaaga agaacaagaa aaaacagcag atgaagccaa gtgacttttt ctaaaatctt
    15721 ctttacagta ggttgataat atgttagtat tttatggtga gtgcaaaagc acttaactat
    15781 tacgatattc cgctgtgaga aaagctcata agaatatttg gaataaggag aagaaaacca
    15841 tgaatccatt aatcgaagaa ttaacaaaag aacaattacg ttctgacatc ccagcgttcc
    15901 gccctggtga cactgtgcgt gttcacgcaa aagttgttga aggtactcgt gaacgtatcc
    15961 agttatttga aggtgttgtt atcaaacgcc gcggtgctgg aatcagcgaa acttatacag
    16021 tacgtaaagt ttctaacgga gtgggcgttg aacgtacatt cccattgcat acaccacgtg
    16081 ttgcaaaaat cgaagtagtt cgctacggta aagtacgtcg tgcaaaattg tactacctac
    16141 gtgcattaca cggaaaagct gctcgtatca aagaaatccg tcgttaatca tcgttatcag
    16201 acagagaaag aacccttggt attcaagggt tcttttttta ttatctgttt ttttatatta
    16261 acgatttcta tttggtacat ttttgattaa taaaaagggg caaaaaaggg gcaacaagtt
    16321 acagtttttc tatatcttct ttcaattttt cttttactcc ttttgtcaca tgcaaataaa
    16381 ttttttcagt gatatcacta ttttcgtgac caacgcgatc ctgaatggca tacagaggag
    16441 ttcctagttc cgctaatttt gaaatatggg tatgtctaaa aatatgtgaa ctaagttttt
    16501 tatcaatctt catgtcagct ttatgacttc tcaaataggt gttaattgct gttagttgga
    16561 aaggagttcc tttcgttgtt tgaaatagaa attgaccatt tggatttaat tctagaagct
    16621 cattgtaaat agctatcgct ttttttggta aatcaatttc tcgcattccg gcagctgttt
    16681 ttgtagaatc agattttttc atatcagcta ttgaacgttc tctatacatc atcgtcccat
    16741 ttataactac tgatgcatta ttattggtaa tgtgtacatc atctttactt aatgcgattg
    16801 cttcaccaga cctcatccca gtcaaatata gccactggaa aaggagagaa tatcttttat
    16861 tgtgtgaagt tgtgaaatct actagtctat tatattcatc atcttctaaa aatttatctt
    16921 taatttttat cgtttttgac tctcttttat aatcaataac tacttcatcg ataggatttt
    16981 tttctacata accttttttc atagcatatg aaaaaagaag attcaatttg gatttaatta
    17041 cactgacgta cttatttgac aagtcatctt tatatatcat gtcttcaaaa atattattca
    17101 aatctattgt attaatacca gaaacgatgt aagtctcagg tatcttcttc tttatagtgt
    17161 ttaatatatt attcgtagga taatatgtag attccttaac ttgtcttttg tatataacta
    17221 accattcttc aacaagctca tgaaatgtta gatcaggctt atgaagtgtt ttttcgttta
    17281 attttatatc aattttttta tttaactcta gcaatgccac tttctgagtt tctcgagatt
    17341 tatttttata agtaatgctc actttttttc tttttctagt ttttggatca atatatcgct
    17401 cattatattt atatactttt tttccgtttt tatcagtttt agtttcgatc cacattgttt
    17461 tcatctccta tttgttgcta taataggaat agataagtaa gccgattata gcaggtttat
    17521 ttttcatcac gtccacaaac tttggcgagg gaggggcgtg tttttgttag ttattgtggt
    17581 aggttatcta aagcgtattg tgcttgctca tttgtaaaac cttcaaatat aagttgatcg
    17641 tacaattgcg aatctgacat tgatgcccaa tcatcgtaac tttccgcttt agccaaagct
    17701 tgttcgttgt aatcgacatc aacattagcc agcgcataat cgattgcatc acttggatat
    17761 tcttcaaact ctagttgttc acgcaaacct tgttcagaca taccagccca acctagatag
    17821 ctttcagctt tgctcaatgc atttctgtat tcacgaggaa cactttcttc ttgagtaact
    17881 tcttctatag tagtttcagt agtttcagtt tcttcttcaa cgactgtaga ttctgctacc
    17941 gattctgcag aagacacttc tgtcacgctt tctttagttg tttcagcgac ggtattttta
    18001 gcatcatcac tgcctccttg cgaacctata gcaataaaca ccacaacaac cgctaacaac
    18061 caaaaccata cccgtttata aaacggtttc ttaactttat acattttccc atcttgaccc
    18121 ataacttttt ttgccattta aatatccctc gcttcttgtt ataatatatt tgtgatctca
    18181 gaaatgaggt atgagtccgt gttgcagcac gggctttttt ctttataact tttttagaga
    18241 ttataggcaa aatagtaggg cataaaaatg tattattgaa ttccgtattt agaaaatcct
    18301 aattgaactt caccggaagt cttttgctgt gttgtacgca atgcttcttc ttcagacatt
    18361 ccattctgta ctttccatgc aacaggcgac atcccgtatt tgttaacaaa atcagtaagt
    18421 gataaagtgt cagcgtcttg ctgagcgctt gtttgttggt cttctggatt ctgttgagat
    18481 gctgcttgtt gttctttctg atcttgactg ataatattgc cagcatcatc tgtagtcaat
    18541 ccattttcat aaagggccac gccgaaagct tcccactctt tgttggacca atttgcacga
    18601 tcagctggag ttgactgtaa agtgcgttgt ttcatctgtt catatgtttc ttcttgaggt
    18661 gcggtttgga ttgtactctg actggagctt ataactgttg ggctaggttc cgccgtagct
    18721 tggttggagc ttgtaactgt tgaactagaa tctgttttag atgtagattt gctagtagat
    18781 gaactggttt cagttgtttc ttttgtttta cttatttttg tttcttggtt agaagtggta
    18841 tctgttgatt cagctttttt attatttgaa caagctgaaa gtagcagagc agtacttaac
    18901 aacaacataa cgctaacttt tttcatttta taattcctct ttctcgttgt aatatgtgtg
    18961 ctaacacggg cttttttata taagaaaacg ataagcgctt tctggaagcc cgtaaagatt
    19021 ctttaattcc tcgatttttt taggatattg atcattatct tctttataaa gagaaacaat
    19081 gagattagca gcaaagcaat tagcttcgct ttcagatttg cttctagatg ttcttgttga
    19141 tacataatag ctggataagc cacgatgaaa aatagcgtga cctaattcgt gagcgcaaat
    19201 gtagaatctt tcctcagagt ctcgcagttc atcatttaaa aagattatcg cacgatctct
    19261 aatttcttga aactgcccct tgggattctc gataaaagga acgtattgaa ttttaatgcc
    19321 catcttttca caaatataaa aaggattagc ggactggtat ttccgcttca actcctcgac
    19381 taaattaatc gtatccatct ccataagctc acatcttttt gcctttttct ttgtcttctt
    19441 tcacaatatc ccagaaagtc gctatcagga tatcttttac gcgctgtatt tgttcgggtg
    19501 tcaatgtttc cccaccataa gacatattaa catttgagtc tagtagttta tcaagttcaa
    19561 ccacttcctc ttttgtagcc cacttgggaa cattattatt tcccaataaa taatcagttg
    19621 tgacaccaaa ataatcagca actttcttta agttctcaga ttttggcgag gctttatccc
    19681 atcttcttat ttgtccatta gagatgccca cctgtctttc tacttctgct atagtcacat
    19741 gcttttcgtc tgctaattct ttaatcttag taactaaact cattattatc aacctttcaa
    19801 agctgaaaag aaaataaata gcttaaaagt tatatttttg gttgacaatt agcttttaag
    19861 ctagtatatt taattcgtaa gctaaattgt tagctaaata agagc
//
LOCUS       DAZKCH010000054        18937 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000054 DAZKCH010000000
VERSION     DAZKCH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.054"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..2144
                     /locus_tag="ACG84X_001909"
     CDS             <1..2144
                     /locus_tag="ACG84X_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HFP9127757.1"
                     /translation="FPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTDLEGT
                     SAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKTKGNV
                     LWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWKQKGL
                     VFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVLFEYS
                     RSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDALASAT
                     LSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEMAAGA
                     AVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIKHLIQ
                     LISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQVANNR
                     LNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPSHSKT
                     AIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQESFFFS
                     GTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGGQRQR
                     LALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAKACDQ
                     ILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            2113..3528
                     /locus_tag="ACG84X_001910"
     CDS             2113..3528
                     /locus_tag="ACG84X_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFP9127758.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            3561..4595
                     /gene="sppA"
                     /locus_tag="ACG84X_001911"
     CDS             3561..4595
                     /gene="sppA"
                     /locus_tag="ACG84X_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFP9127759.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            4597..5118
                     /locus_tag="ACG84X_001912"
     CDS             4597..5118
                     /locus_tag="ACG84X_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFP9127760.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            5115..5501
                     /locus_tag="ACG84X_001913"
     CDS             5115..5501
                     /locus_tag="ACG84X_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFP9127761.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(5997..6069)
                     /locus_tag="ACG84X_001914"
     tRNA            complement(5997..6069)
                     /locus_tag="ACG84X_001914"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6034..6036),aa:Lys,seq:ctt)
     gene            6450..7019
                     /locus_tag="ACG84X_001915"
     CDS             6450..7019
                     /locus_tag="ACG84X_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFP9127762.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            7006..7866
                     /locus_tag="ACG84X_001916"
     CDS             7006..7866
                     /locus_tag="ACG84X_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFP9127763.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            8056..8760
                     /gene="yycF"
                     /locus_tag="ACG84X_001917"
     CDS             8056..8760
                     /gene="yycF"
                     /locus_tag="ACG84X_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFP9127764.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            8765..10600
                     /gene="walK"
                     /locus_tag="ACG84X_001918"
     CDS             8765..10600
                     /gene="walK"
                     /locus_tag="ACG84X_001918"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFP9127765.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            10597..11913
                     /gene="yycH"
                     /locus_tag="ACG84X_001919"
     CDS             10597..11913
                     /gene="yycH"
                     /locus_tag="ACG84X_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFP9127766.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            11914..12783
                     /locus_tag="ACG84X_001920"
     CDS             11914..12783
                     /locus_tag="ACG84X_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFP9127767.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            12838..13647
                     /locus_tag="ACG84X_001921"
     CDS             12838..13647
                     /locus_tag="ACG84X_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFP9127768.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(13750..14379)
                     /locus_tag="ACG84X_001922"
     CDS             complement(13750..14379)
                     /locus_tag="ACG84X_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFP9127769.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            14549..15841
                     /locus_tag="ACG84X_001923"
     CDS             14549..15841
                     /locus_tag="ACG84X_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9127770.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(15917..16579)
                     /locus_tag="ACG84X_001924"
     CDS             complement(15917..16579)
                     /locus_tag="ACG84X_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFP9127771.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            16804..17088
                     /gene="groES"
                     /locus_tag="ACG84X_001925"
     CDS             16804..17088
                     /gene="groES"
                     /locus_tag="ACG84X_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFP9127772.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            17139..18764
                     /gene="groL"
                     /locus_tag="ACG84X_001926"
     CDS             17139..18764
                     /gene="groL"
                     /locus_tag="ACG84X_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFP9127773.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         6444 a         3060 c         3921 g         5512 t
ORIGIN      
        1 catttccttt tgtgcagcaa caagatgaaa aagattgtgg tgttgcttgc ctttcgatga
       61 ttttaaaata ttttaaaact gatatcccga ttcataaatt acgggaccta tctgggactg
      121 atttagaggg tacttcagca tttggattga aaaagacatt tgaaaaattg tcttttgatt
      181 gtatggctat tcaagcagat agtgagatct ggaaagaaag agatcttatc ttaccattaa
      241 ttgcacatat attggttgat aacagctata tgcactacgt tgtaatttat aaaacgaagg
      301 gaaacgtact atggattgca gatcccgcta atggaaaaaa tagaaaaacg attgaagcgt
      361 ttcaaaaaga atggacaggt attcttttat tacctatgcc tagagaaact tatattccta
      421 ttaaagaaaa agtagctgga ttaagttctt ttttgcctat aatttggaaa caaaaaggat
      481 tagtattcca catcgtttta gcatcgattt tcattacgtt ttttggcata ggaagctcat
      541 attattttca aggtattctt gattttttca tccctaatca agcacgttca actttaaata
      601 taatttccat tggcttgatc gctgtctatt tatttcgggt attgtttgaa tatagtcgta
      661 gttatcttct tattatttta ggacagcgaa tgagtatggc aattatgctt cagtatttca
      721 aacatgtgtt aactttacca atgaattttt ttgctacgag aaaatcaggg gaaattattt
      781 ctcgttttct tgatgccagt aagattattg atgctttagc aagtgctacg ttatcaatat
      841 ttttagatat tggtatggtg ttgcttgttg gggttacgtt agctattcag aatagtacgt
      901 tgtttttaat cactctatgc tctttgcctt tttatgtagt tgcaatattc gctttcgtga
      961 aaagctatga aaaatcgaac agggaagaaa tggcagccgg tgcagctgta aattctagta
     1021 tcatagaaag tcttaaagga atagaaacaa ttaaagcata tagcggtgaa gagaaagtat
     1081 ataaccgtat agaccatgaa tttgttaaat taatgaaaaa atcatttcgt acggttacgc
     1141 ttgataatat tcaacaagga attaaacatt tgattcaatt aattagcagt gcattaattt
     1201 tatggctagg ttcttatttt gttatggata atagaattag tctaggtcaa cttatcacat
     1261 acaatgcttt actagtattt ttgacagatc ctttacaaaa cattattaat ttacaagtga
     1321 aaatgcaaac ggctcaagtt gcaaataatc gtttaaatga aattttcgcg attgattcag
     1381 aaaaatcgaa ccagtctttt gaatatatgc tttctgaaca attatttcaa caagatatca
     1441 ctgtaaaaaa cgtttcattc tcgtatagca tgaaggcccc aacgttgaac gaaatttcat
     1501 gtacaattcc ttcgcacagt aaaacggcta tagttggagt tagtggttct ggaaaatcaa
     1561 ctcttgcaaa gttatttgtt cgtttttatg aagcatcaga aggatcgatc cattatggaa
     1621 acattaatca cttagacatt ccttttcaga tattacgcga tcgagtgaca tatttgcctc
     1681 aagagtcatt tttctttagt ggaacaatca ttgagaatct tatattcggt ttagatagcc
     1741 caccaagttt cgaacaaata atagaagttt gtgagatagt ccaactaaat gaatttatta
     1801 atcaacagcc attacgttac gagacattgt tggaagaagg tggaaataat ctttcaggag
     1861 ggcaacgaca acgattagcc ttagcacggg ctttattaaa aaatccggac atattaattt
     1921 tagatgaagc aactagtgga ttagatacct tgttagaaca tgcaattatg aattatctcc
     1981 tcaatttaaa agaaaaaacg attattttta ttgcgcatca tttaccaata gcaaaagcat
     2041 gtgatcaaat tttagttctc catgaagggc atttggtaga aaaaggaacg cacgatgaac
     2101 ttcgttttgc cgatggtatc tatcaaaaat tatgggaaat ctaggagagg gaaacaattt
     2161 atgcagaata ataattggtt cgaacattct agtatctata ctaaacaaca tcatagcttc
     2221 taccgttggg tgttataccc tgtaattctt tttttatgta ttattggatt gtttttaacc
     2281 tttgctaaaa aagaggttgt tattcggaca acggctcaat tgaaccccga aaaaatagag
     2341 aagttacaag tgccattaga agctaaaata atggaaaact tcctaaaaga aaatcaattt
     2401 gttcataagg acgatgtgtt ggttagattg gattgttctt taatagagaa tgaaaaggct
     2461 cagatagaac aagaaaacca acgtattact caacaaataa agatggctca gctatttatt
     2521 gaaagtataa gtaaaggaaa aaatttgttt tcaacggatg acagttttgg ctacagtaat
     2581 caattaaaga gcatgttgtc agaaaaagaa tcactccgct acgctttgaa gcaaagtgaa
     2641 ttaaatgatc aaaagcaatt agaagtatac gaaaagacaa aaagacaact agaaaaacaa
     2701 attgagagtt cagatagtaa attacaagaa tggcaacaag tacaggtagc ttggagtaat
     2761 aatcaatcat taaaagattt ttcaaaagaa atgatggcaa actatgagaa ttggcaagaa
     2821 caactaaata atgtttctga tgatcaaaaa aatcaagtga aactgacaat ttcagcaagc
     2881 ataaatgaac aaattgagca actaaaaaaa gaagtagaac agtatcagtc agaaaaagct
     2941 aaattagtta aaccaactac ttctgagaat gacagaatta gtcaaacgga aaaaggaaag
     3001 caagagctag aacaagcaat aacaactgta aaacaaacag ttacagagct aaatgaaaaa
     3061 caagagaaga accagtcagt tatcaaaagt ttggacgatc aactttcaaa aggaatacta
     3121 aaagctcctg tatctggaac ggttcattta aatgaagaaa caaagggaca agcagaacta
     3181 gccaaaggaa cagtgcttgc agaaatttat ccgatccacg aaaaatcaaa aatgaaattt
     3241 acagcacttt tacctgcgaa tgaaagtacc tatattaaag aagggatgaa ggttcatttt
     3301 aaattggatc aaaaaggtgg ggctccgatt acgatcgacg gaactttaga tgaaatttca
     3361 gaaaattcta ctgccactga gaaaggtgtt ttttatgcag tgaaaggaac gttaaaaaca
     3421 actcaatcgt ttccgtttcg ttatggatta actggagagt tgtctttaat tgtaggagaa
     3481 aaaacatatt ggcaacaaat tgtcgatgtg tttctaaata aaaaataatt atttttacta
     3541 agaatatagg aggagtttat atgaataaaa gaagatggat tgctgtggga gtagcgtgcg
     3601 gattattgtt actatccatt atcgtcgcgc taattccagg aaaagataaa gaggaagcat
     3661 caaatacaac cctaacagga ataaataaga ttttttacgg atctaacgaa atcacagaag
     3721 aaacgttaga agaaggcgca tcaaataaaa agattgtcaa actatccgtc aatggagtta
     3781 ttgcagatac aggtgaaagc aatcttttta gtagggaaca atataaccat cagaattttt
     3841 taacacagct aaagaaaatt caagaagaca aagcggttaa gggagtgtta ttagaagtaa
     3901 attcacctgg gggaggaata tatgaaagtg ctgagattgc taaagaaatg gcaaaaatta
     3961 aaaagctaga tattcctatc tatactgcat ttaaaaatac agcggcaagt ggagggtact
     4021 acatttctgc tggttcagat aaaatatttg ctacggaaga aacaacaact ggatcaattg
     4081 gtgtcattat ttctggttta aattattctg gcttattaga aaaacttggc gtaactgatg
     4141 cgacgtataa aagtggtgca ttaaaagata tgatgtcacc tcaacacaaa ccttcagagg
     4201 aagagaataa agttatacag gaatttgtga tgagtgctta tgatcgtttt gtcaatgttg
     4261 tagcaaaagg aagaaatatg gatactaatg cagtgaaaga acttgcggat ggaagaattt
     4321 atgatggtaa ccaagcagta gaaaatgggt tggtggatca aattggttac tctgaagatg
     4381 cattagattc cctaaaaaaa gagaagaaat taactgatgc gacggttata gaatataaaa
     4441 atgacacaac tggctttgct tcttcttggt taggtaataa gattgctgaa tggcaagggc
     4501 taaaggcaac tacatcagat cgtgtaattt cagtttttga aaaacttgga ttttctgata
     4561 ctccaaaacc aatgtattac tatggagggc tataaaatga ataagaagag tggcattgaa
     4621 actttgccta attatgtatt tgcgggattt tggttacgat tttttgcttt tcttattgat
     4681 ttaatttgta ttagcatcat cacccatgct actataggtc tcttttacaa aatcatggga
     4741 ctggaatctg acaaatccat tattactttt tatggtatag cgtcattagc tatttattta
     4801 acctattttg tacttttgac taagctgaat tcaggacaaa caattgggaa aatgattttt
     4861 gggataagag tagtgagctt tgaggaaaaa gagctaagtt ggcaaactat ctttattcgt
     4921 gagtgtatat gtaggtttat attaaaaaat tttgtatttc aaattgggta tttggtggct
     4981 gctttcacgc ccaagaaaca acatattggg gattattttt ctaacacgtc agtggttgtt
     5041 attcgttcat tagaagctat taactatggt caaaaaattt ctaattctaa aacacttaat
     5101 ctggagagaa ttaaatgaat aagagaaaaa cagagtttat tttgatttta attagtggaa
     5161 taacagggat tttatgtagt cttttagcat tgatgggtgg tatgtttcta tcttctattg
     5221 attcaactac tttaaatact acagaactaa ccagtaagga tatagatatg ttagtcaatc
     5281 taagcgggaa tgttgtttta tttggaggaa ttaccctagt tttttcgata atgattttca
     5341 taataggttt tttagtaaga aaaaatcaaa aaacagtggt ctatggtatt agtttactca
     5401 ttttatctat tattccattt tttcttttaa cattattgtg ggtaattcct ggagttttag
     5461 gtattattgc gggattgatg cttctaataa gaaaatctta attaggcaat gtgtagacaa
     5521 cgtgaaacga ttaatcaatt aaaagctaaa tacgttttga gaaatgataa cttgtagtcg
     5581 atggaagaca tgtagataaa aaaactacgt gtcttttatt tattctaatt ttttcgaaaa
     5641 aaagacactc tctgattgtt gtattaatgg aaaaggggaa agcagcaagt aaatttagtt
     5701 tttctattaa atattcttca ctttttaacc ttttatagta cttagattta atcctatatg
     5761 tttagagagt tcattggcag catgattttg caaagcttct cgaattattg ttatattaga
     5821 aactttactg ttcataatta tgcttctttt ttaactcaaa gtccaaaggg ctacagtgga
     5881 ctttgagtta aaaataaaaa gccctagtta ttttgaaaaa taaaaaaaga acagcgtaaa
     5941 tgttttcgaa atgctttcgc accaacattt acctgttccg tgggtttggc acccaatggg
     6001 ccgtgagggg ctcgaacccg cgacccgctg attaagagtc agctgctcta ccaactgagc
     6061 taacggcccg tacaaaaagt acttaataat agtagcacta agaattttaa aatgcaagac
     6121 tacatttaaa gaaaatcaga aaaatcttta cttccttata ggaaatcatt catagattat
     6181 tcacatttgc tcgctattat ataagcatac caacaaacaa agttcttgca agagaacaaa
     6241 ccctaacact tttttcattt tttactcctt tcccgccgtc tccccggcgg gtctcctgtt
     6301 cttaacgata aaagacaaga aggcttagcc ttcttgtttt ttgttttcat ggaatcccgc
     6361 taatcaaatc acctagttaa agcaactaga ttgaatgttt atcataagtc tgatatcatg
     6421 tttatgaaat gaaaaaagga gcggttatga tggaaaaaat gcgtcagcaa ttaatggagt
     6481 gggggaagga actagaaaca ttccgtctgc ctcactggga agaactccct gacttagaac
     6541 tttatatgga ccaagtcaga acgttagttg atcgttatct ttcacctgtg atacaaggag
     6601 aaaagcatcc attgcttacc tcttctatgg taaacaatta cgttaaacta ggtttgatac
     6661 cagcaccagt taaaaaaaga tataacaaag aacacgtagc atttttactt gcaatcacta
     6721 cgttgaaaca agtattgact attcctgaaa tcaaagaagg gatattgttc caaggaaaaa
     6781 cagtaggaat tcgtgaagcc tataatctat tttgcgatga acaagaagca gctgtgtgga
     6841 tggtcagcca attagcacaa ggtaaatctc atccgcaaaa attcgaccag gcaacccctg
     6901 tagaatatat tgctgtaaga gcggcaactt tatcgtttgc aatgaaactt cttgcggaaa
     6961 aaacgattgt tctagaaacc gaatatttaa aagaggagaa aacaaatgaa aaacaataaa
     7021 atcgcaattt tagtagattc aggtacggat gttccagaag aattgataaa aaaatacgag
     7081 atgtatatga tcccattgaa aattatttat aaagatcagg tatatacaga taaaattgac
     7141 attacccctg aagagatcta tcaacgtttg ccagaggaaa tccctggtac atctttgccg
     7201 gatggtgagt cgatcacaga aatctttgag caaatcaaaa aagacggtta tgaaaaggta
     7261 cttgcggtaa caatttccag tggattgagc gggacatata atgtggttcg tttaattgca
     7321 caacagcaag aagaattgga agcatatgta ctagatacga aaaatattgg tattggtgca
     7381 ggtttttctg cgatccaagc agcaaaatgg ctggaagaag gagtagaatg ggatcaactg
     7441 atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt tctttaatgt tgcgacattg
     7501 gaatatcttc aaaaaggtgg acggatcggt ttagttgctt ctattgtagg aaccgcttta
     7561 aagcttaacc caatcatctc atgtaatgaa gaagggattt attacacagt aggaaaagct
     7621 aggggacgta aaaaaagttt ggataaaacg gttgcttacg tcaaagaaaa aatcggtaat
     7681 gcaaaggtct tcaacttagc tgttgcccat ggggatgcga aagaagaagc aattgaaatg
     7741 gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa tctactttgg ccagatttct
     7801 ccggcattag tagtccacac tggtccggga ttattgggtg tcggtgtaca agttttagaa
     7861 ggataaatca aaaaaaggaa acactgaggt gaaaatcagt gttttccttt tttattgaag
     7921 ttagaacaaa aaataataaa gtattttgca ctttcatttt aattttctct tttgttttat
     7981 aggcaaagat gaaacaaaag cagaaatacg gtataatgag aaggtatgac aataatatat
     8041 aagaggtggc tctttatgaa aaaagtttta gttgtcgatg atgagaagcc gatttcggat
     8101 atcgtcaaat tcaatttagc caaagaaggc tatgacgttt atactgcata tgatggggaa
     8161 gaagccttgg aaaaagttgc tgaggtagaa cctgatttga ttttacttga tttgatgcta
     8221 cctaaaatgg acggcttaga agttgctcgt gaggtacgca aaacttatga tatgccgatc
     8281 attatggtaa cagccaaaga ttctgaaatt gataaagtcc taggcttaga gttaggcgcc
     8341 gatgattacg tgaccaagcc attttccaac cgagaattag ttgcacgtgt caaagcaaat
     8401 cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg cagcacctgc ggaattgacg
     8461 attggtgatt tgacgatcca tccagaagct tacatggtga cgaaacgagg agaaacaatc
     8521 gagttaacac atcgtgaatt cgaactactc ttttacttgg cgaagcacct tggacaagtg
     8581 atgacaagag aacatttatt acaaacggtt tggggttatg attattttgg agatgtacga
     8641 acagtggatg taactgtacg tcgtttgcgt gaaaagatcg aagataatcc aagccatcca
     8701 aattatttag tgacacgtcg tggtgtcggt tactatttgc gtaacccaga acaggagtaa
     8761 ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat tttaagatcg ctattacctt
     8821 tattctgatt ttattgatct cgatcgaaat tattggtgcc tactttatac gtggtttaga
     8881 acgttccacg atcaatacat ttattaaaga tatgaatcaa acggtggaat cattagcaac
     8941 aacaatcagc ccggaattga atcgaaaaga taatgcagat gatgaagagg taaatgcgaa
     9001 tatcaaaaga tttattgaaa acagtgcgac tagcgatatc atcgaaatac gggtcgttga
     9061 cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa caaagcgctg tgggaaagaa
     9121 aaatgattat gttgatatca atgatttcac gactaaacgt tatgttgctt tagataacga
     9181 cgataaacgg gtgaatatca atgttcaacc gatcctgtcc ccgaccggcg atgccgttat
     9241 cggggctctt tacgtcaaaa gtaatatcga acaaaaatat tcggaaatca ataacacagc
     9301 agtcattttc tttactgcct cactaattgc ggcatttatt tcaatgatcg tatctgtttt
     9361 agttgctcgt tcgattacac agccgatcgg tgaaatgaga gaacaagcca ttcgaatcgc
     9421 tagaggagac tacagtcgga aagtcaaagt gcatggacaa gatgaacttg gacagctggc
     9481 tgataccttc aatcagttag ctgaacgtat tgaagaagct caagatacaa tggaagctga
     9541 acgcaatcgt ttggatagcg tgctatccca tatgacagac ggcgtcattg cgacagatcg
     9601 caggggtaaa gtcattacga tcaatgatat ggctgtttcc ttgctagata tcaaaaacga
     9661 ggaagcaatc ggacaatcga ttttgacact tttagatatc gaagaagaat atacgttgcg
     9721 gaaattatta gaagatccaa acgaaatggt acttgaccgt tcaaccagta cattggaaag
     9781 tgatcagatg atcttgcgag tagacttttc tatgatccgt cgcgaatcag gttttatcag
     9841 cggattagta gctgtcttgc atgatgtgac agaacaagaa aaaacagaac gggaacgtcg
     9901 tgaattcgtc tctaatgttt cccatgaact tcgtacaccg ttgacaagta tgcgtagtta
     9961 tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa gtagcaccaa attttttgaa
    10021 ggtaacgcta gatgaaacag accgaatgat tcgaatgatc aatgacctct taaatctatc
    10081 tcgcatggat acaggtaata cccagcttca attagaatat gtcaatttca acgagttagt
    10141 gaattttgtt cttgaccggt ttgatatgat ggtgggaaat caggaaaaaa attataagat
    10201 ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta gatacagata aaatcatcca
    10261 agtagtcgat aatatcatga ataacgcgat caagtattca ccagatgggg gaacgattac
    10321 ttgtcgctta ttagaaacgc ataataacgt gattttaagt atcaccgatc aaggattggg
    10381 gattcctaaa aaagatctga accgagtgtt cgagcggttc tatcgagtag ataaagcacg
    10441 tgcaagagca caaggtggga caggacttgg attagctatt tctagagaag tgattaaggc
    10501 gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa gggtcgactt tttatatctc
    10561 gctgccatat gaaccttatg aggaggaatg gtgggaatga gaatctctga aaaagtcgtt
    10621 cgtataggac tcattttgat ggttgcgtta agcatatact tctcttatgc aatctggctg
    10681 agcccagcag gaaaaagttc aatcaacgta gatgagacaa acactcaaat gatcgagtct
    10741 caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc atgttacatg gcaccattcg
    10801 ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc gattgcaatt gatcatcgat
    10861 aaagcaagat ttggaaagct ttctgaagta gtttcaggag acaaatcaca gtttgaacag
    10921 gtgaaaaatc tgaactctgg ttttgagttg gcctataatg cgcctttttt gctaagagaa
    10981 tacaaggaag catttgattt agatttagat gtgtcgaact tggcaaaaga aagcgaaaat
    11041 atgtatttta ctagaataca attcgatcaa ggaaataaaa aaatccgatt tttgaattat
    11101 tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt ggacagatat caataaagaa
    11161 ttaacagcaa aagacacaaa atggacagaa atgacaacag aaccatcgac gatcgacacg
    11221 caatatgcta cgaaacattc gatcaaactg aagaagtata gttatatcct gtcacagcaa
    11281 ccctatacac tttttagaaa tgcttttttc cagaaaccag atagcgtgaa aaataatgat
    11341 gaaagcaatg aattgatttt ttacggtggg aatgaaacaa tgtctatcca ttcggaaacg
    11401 caagtagttg attttcgtgg agagctgcca gagaaaaaag aaaatgctag tgtattttct
    11461 gaaagtttcc cctatattag caaattaggc agttctttag ggaacctcag atattttgac
    11521 cgcagtgaca atacgatcga ttatcggata ttcgtggaag gcttcccggt ttttgggaca
    11581 gacagcagag gacagattgg tgtggaagtt ggcggtgaaa cgaatggttc tgtgcaagtg
    11641 aatatccaaa ccagtttgaa tacgattcaa gtgccgatac cttcagacga agaagtagaa
    11701 cttgcaagta cgaatgaaat catccagcag ttaaaagcta agggagcaga tagcaacaag
    11761 attggttcag tgatcgttgg ctatacatgg caaaatgtca aagaaacgaa tcgtgtcgtt
    11821 gatctcttac ctgaatggta tgtgaaatat aaagataact ggtattcagc taacgacctt
    11881 ctggaaaaat tacctggatt ggaggcgaat taattggatt tcaaaaaaat cgaatggata
    11941 tttttcgtcg cttttttagg gttgaatgtg tttttattca gcagttatca tgacgcggta
    12001 taccaagaaa acaatgtcat tcgctctaat cagactgaat caatccaaca acgtctggct
    12061 agcgacgata tcacttacac ggggaagatt tcgtctgaga acaagcaagg ctattatctt
    12121 agcgcggagc agaccaatct tagcacttca ttagcgaatt atcgcaaggc tggtaaaagc
    12181 ggcttgctgg caagtggtgt gtttttagac ggtgatgttt tgacgaaatc tttatccagt
    12241 tcagatgctg aaaagaacgt gatcgatcca gataaaatta gtagttcctt ggaagatttt
    12301 ttatctaaca aagacaatat tttattcggt aatgattatg tgtacacgaa aaacttttct
    12361 catttagaag aagaaccact agaaatccaa gcaagccaag agtatgaagg catcccattc
    12421 aatgatgata cagcaaaaat cgttctttct ttagaaaaaa acgataatga ttatagcatc
    12481 acgaaataca tgcagacgca tttatctgat atcgagcagc tgcgcgaaaa gacggaactg
    12541 tatacggaag aggaagcaat caatacattg tacatcaata acaaaatacc aagaggatca
    12601 aaaattttat ggcgtcagct agcttattcc tgtattctga aagtccggga aaaaaatgtg
    12661 tatgttcctg tttggcatgt agcgatcgaa acaagcgata aagtggtcca aattgagagc
    12721 gtcaacgctt tcagcaatac gatcgtgaca aacaatactg taccaaaagt ggaagatcaa
    12781 taaaaaagcg agtataatga aaaaagttta caaagtaaga agggaagtag gagtcaaatg
    12841 gctgaagaaa aaccagcttt taaaatcagt atcctagcaa gtggaagttc gggtaattca
    12901 ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg caggacttag cggtaaaaaa
    12961 atcacttcct tgatggctca aattgatcgg acaccggacc aattagatgg aatacttgtg
    13021 acgcatgaac atcgagatca tatacatggc gtgggtgtct tggctcgtaa gtatcatttg
    13081 gatgtttttg ccaatcagca gacttgggaa gcgatggaac cactgattgg aaatgtacca
    13141 gtggaacaaa aacatctatt tgagatgggg aaagtcagaa cattcggcga tatcgatatt
    13201 gagagtttcg gcgtctccca tgacgcagcg gctccgcaat tttatcgttt ccataaagaa
    13261 aatcggtcat tcgtcatgtt gacggacacc ggatattgca gtgattatat gcgaggtgtc
    13321 attgaaaatg ccgatggtta tttgatggaa agtaatcatg atcttgagat gttacgcatg
    13381 ggaccttatc cgtggaattt aaaacagcgt attttaggag atagaggaca tctttccaac
    13441 gaagacggtg cacttgtcat gactgatgtg atcggtaatc ggaccaaacg aatctatctt
    13501 ggccatctta gcaaggaaaa caatatgaaa gaacttgctc atttaacaat ggaaaatgtt
    13561 ttgaaagaaa aagattttgg cgttggacat gattttgaaa tctatgatac agatccagat
    13621 gaagcaactg agctattttc gatttaaaca gttcaatcaa taaaaatata aaaagcagaa
    13681 gataaaatca atcagggttg gttttatctt ctatttttat ttttttagca tattaaaaaa
    13741 ataaccgtat tatcgactga ctacactgat gtgctgcttt tcatgtttct catccagtat
    13801 ctcatctact aatgcaatcg cgtaatctgc catgctgatc gtactgtcgc tagcagcgtt
    13861 tctttgtaaa taatcatcac ttaacaaata agtacctgta cgtttgccat gtggatcaaa
    13921 taaagaagct ggactgatat aagtccaatg tagattttta gattgtttca attttaacaa
    13981 tccttcgtac atattgaaag ctgttggata gaagggtgca tttttaggta cttggtcaat
    14041 catacgagtc gtcttttctg tatctaagaa taacgaagag gcacccccaa cgacaattaa
    14101 gcgtgtatcg gttccttcaa gcatctcaat caaatgggac aaagaagttt gatgcatttc
    14161 ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca tcaaaagatg caagatcagt
    14221 agttgtcaac tcaaataaat ccttttgtat aaacggaaca tctgatggca atttttctgg
    14281 atgacgcacg attgccgtca cgtctaaatc tctggacaat gcttcgtcta aaataaatga
    14341 acctgcatgg ccagtagctc caatgagtgc aattttcata aaaaacctcc ttttttattc
    14401 ctgtccattg taagcagttg ctgaatattc gtcaaagaat ccgatttttg aaaagctcag
    14461 tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt aaattaagaa aactgattga
    14521 taaaaataga agttgaagga gataagaaat gaaagagtgg ttagatcgtg cctttttacc
    14581 aatgataaca tctgttgtga atcttagacc cttaactgct ttgcgtaatg gaatgactta
    14641 cacgatccca ataattattg ttggctcgct gtttttctta tttgctcatt ttcctgtgga
    14701 ttacatcgct cagtggatag acaaaacagg attttctatg tattttacac aagtatacca
    14761 ggctacattt gatgtgatag ccttttggat cgtttttgcc attgcatacg cttatgcaaa
    14821 agaagaagac atcgatcgct taccagtcgg cataacagcc ttgtctgctt atctactgct
    14881 tattcagcca ctaaatactc agatagatac tgtctggaca ggtgctgaag ggatactagg
    14941 agcagttaca actgggctca tcatcggatg gggctatgca cgtttagtaa gacttgcgaa
    15001 agggtggaag caaagagaga agatacctga aaatgtttgg cagtctttta cttcattgat
    15061 tccaatcatt gttatagtca cttttacgct tatcggttca gcggtttttc aacatttgtt
    15121 cagaatgact gttgttcaag gagtatggac atatgtccag cttcccattc aatcgttcat
    15181 agacacgttg tttggtgtgc ttttattagg tttttttgtt ccgtttttat ggttatttgg
    15241 tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc gtcttgcaag cgaattcatt
    15301 agcaaatgca gaaatcttag cctcaggaca agagttgacg gtggcaaatg gcggacatat
    15361 cgttactcag caatttctcg atcagttcat gacggttacg ggtgctggat tgacgttagg
    15421 ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa tacagagaat taggaaatct
    15481 tgctctttta ccagcctttt tcaacatcaa tgaatcaatt attttttcca caccgatcgt
    15541 gatgaacccg atgatggctg ttccttttat tttcgcaccg gtcgtttcag gattgattac
    15601 ctattccgct ttatattttg gattcgttcc tttatttaca gcagtccaag tcccttggac
    15661 aacaccgccg atcctctcgg gtttcttagt aggcggagtg cctgcagcga ttttacaagg
    15721 tatcgtgttg tcaattagtt ttttcattta tttcccattt ttgaaaaaaa tagattctgc
    15781 aaactgcaaa aaggaaagac agacaaaaaa tgatggagca gcagaaaaga tgaacgacta
    15841 aaaaacaaaa atactcctgt cgctttagat tgggaaaatc accaatctag gatgacagga
    15901 gtatttatag tcatgtttat actagccctt tttggacagc taattgaaca agaacaacta
    15961 atgtgttcat tcctacgtgt gtgatcatcg atgtccagat ccgaccagtt gctttgtact
    16021 ctaggctgaa gaagaaacct aggaaaaagt agattagcag atgaccatca ttatgagcaa
    16081 acgcaaacag caaagagctg atcactgctc cgacccaaaa atttgaatat cgactgatga
    16141 tccccagtat actgcggcgg aatacgaact cttccatgat gggtccagca acagttgtcg
    16201 ccaaaataaa agcgggtgct tccatgatca tctggatgat attttgtgta ttctcggaag
    16261 gggttgcttt gccaaacaat acagattcta acatgacagc gatgctttgc agaatcaatg
    16321 cgacaaagat tccaaccaat ccataaataa caatctttgg agcagaagct ttttttaccg
    16381 ctgattcgat cgctaagggt tcacgttgct taaaataaaa aatagctagg acaacggcgc
    16441 ctagtatata catgactgca gttgctgtga tcaattcaga cgtagatttt acaagtccta
    16501 tcgaagctag gatcaagggt gagataaaaa ttagaccata gcaaaaaatg ctgaggaagc
    16561 tatatttttt taaagacatg taattcctcc ttttaaggga taacaagcat gcaaggcaag
    16621 cttatatcga ttgatttcaa ttatatcata atttcaataa gcagctgtca gaataaaatt
    16681 tcttttcttt gatttaaaag cttgcaaaaa agagggagaa tgagtattat taaaaatgta
    16741 ggttagcact cgaaggttaa gagtgctaac agattaaaaa aagagttatc ggagggattt
    16801 atcgtgttaa aaccattagg tgatcgcgtc attatcgaag tcgcaaaaga agaagaaaaa
    16861 actgtcggag gaatcgtttt agcttctgct gctaaagaga aaccccaaac tgggacagtt
    16921 gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa aagttcctgc cgctgtaaaa
    16981 gcaggcgacc aagttatgtt cgaaaaatac gccggtacag aagtaaaata cgaaggaaaa
    17041 gaatatctga tcgtcgcagg aaaagatatc atggcgattg ttgagtaaat ttggaagata
    17101 aaaaaataat caaaaataat caatgaggtg aatcaatcat ggcaaaagaa ttgaaatttg
    17161 cagaagacgc acgcgcagct atgttacgcg gggtagataa attagcagat acagtgaaag
    17221 taacattagg acctaaaggc cgaaatgtcg tactagaaaa atcttacggc tctccattga
    17281 tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt agaagatcat tttgaaaaca
    17341 tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa tgatattgca ggagacggta
    17401 caacgacagc aactgttctg acacaagcaa tcgttcgcga aggtttaaaa aacgtaactg
    17461 caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt ggcaacaaaa gcagcagtcg
    17521 aagaattgca taatatctca actgttgttg attcaaaaga agccattgca caagtagcag
    17581 ctgtttcttc gggttctgat aaagttggac atttgattgc tgatgcaatg gaaaaagttg
    17641 gaaacgacgg tgtcatcaca atcgaagaat caaaagggat cgaaacagaa ctagatgttg
    17701 tagaaggtat gcagtttgat cgtggttact tatcacaata tatggtaaca gataacgaca
    17761 aaatggaagc tgttctagaa aacccatata tcttgatcac agacaaaaaa atctctaaca
    17821 tccaagatat tctgccattg ttagaacaaa tcttgcaaca atcacgtcca ttgttgatta
    17881 ttgctgacga tgtagatggt gaagcattgc caactcttgt attgaacaaa atccgtggaa
    17941 cattcaacgt agtagctgta aaagctcctg gtttcggcga tcgtcgtaaa gcaatgcttg
    18001 aagatatcgc tattttgaca ggtggtacag taattactga cgatctaggt ttagaattga
    18061 aagatgcaac aatcgaaaac ttaggaaatg cttctaaagt tgttgtagat aaagacaata
    18121 caacgatcgt agaaggttct ggagaaaaag aagcaatcga agctcgtgtg caattgatca
    18181 aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga aaaattacaa gaacgcttag
    18241 ctaaattagc aggtggtgta gctgttgtta aagttggtgc agctactgaa acagaattga
    18301 aagaattaaa attacgcatt gaagatgcat tgaatgctac acgtgccgca gtagaagaag
    18361 gaatggtctc aggtggtggt acagctctag tgaacgttat cagcaaagtt tctgctgtag
    18421 aagcagaagg agacgtggca acaggtatca agatcgttgt tcgtgcttta gaagaaccaa
    18481 ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt gattgttgat aaattgaaga
    18541 acgtggaact aggcactggt ttcaatgctg ctactggaga atgggtaaac atggttgaag
    18601 caggtatcgt agacccaact aaagtaacac gttctgcctt gcaaaatgcc gcttccgttt
    18661 ctgccttgtt attaacgaca gaagcagtcg ttgcagataa accagaacca gcagcgccag
    18721 cagctcctgc aatggatcca tcaatgatgg gcggtatgat gtaagaaaaa gcaacttgct
    18781 tatctacaac tgatcattag tgaaagacag ataaaaagag gctggaacag aagcgtttaa
    18841 ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca aatttttgtg aatttcagct
    18901 tatttccgaa ggagttgctt ctgcttccgc tgtttat
//
LOCUS       DAZKCH010000055        18156 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000055 DAZKCH010000000
VERSION     DAZKCH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.055"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            102..443
                     /locus_tag="ACG84X_001927"
     CDS             102..443
                     /locus_tag="ACG84X_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFP9127774.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            752..1795
                     /gene="pheS"
                     /locus_tag="ACG84X_001928"
     CDS             752..1795
                     /gene="pheS"
                     /locus_tag="ACG84X_001928"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFP9127775.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            1800..4220
                     /gene="pheT"
                     /locus_tag="ACG84X_001929"
     CDS             1800..4220
                     /gene="pheT"
                     /locus_tag="ACG84X_001929"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFP9127776.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(4390..5400)
                     /gene="trpS"
                     /locus_tag="ACG84X_001930"
     CDS             complement(4390..5400)
                     /gene="trpS"
                     /locus_tag="ACG84X_001930"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFP9127777.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            5654..6391
                     /locus_tag="ACG84X_001931"
     CDS             5654..6391
                     /locus_tag="ACG84X_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFP9127778.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            6405..7220
                     /locus_tag="ACG84X_001932"
     CDS             6405..7220
                     /locus_tag="ACG84X_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFP9127779.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            7233..7880
                     /locus_tag="ACG84X_001933"
     CDS             7233..7880
                     /locus_tag="ACG84X_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFP9127780.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            7896..8552
                     /locus_tag="ACG84X_001934"
     CDS             7896..8552
                     /locus_tag="ACG84X_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFP9127781.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            8714..9535
                     /gene="racE"
                     /locus_tag="ACG84X_001935"
     CDS             8714..9535
                     /gene="racE"
                     /locus_tag="ACG84X_001935"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFP9127782.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            9538..10893
                     /gene="rph"
                     /locus_tag="ACG84X_001936"
     CDS             9538..10893
                     /gene="rph"
                     /locus_tag="ACG84X_001936"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFP9127783.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            10894..11412
                     /locus_tag="ACG84X_001937"
     CDS             10894..11412
                     /locus_tag="ACG84X_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9127784.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            11519..12019
                     /gene="cbpB"
                     /locus_tag="ACG84X_001938"
     CDS             11519..12019
                     /gene="cbpB"
                     /locus_tag="ACG84X_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFP9127785.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(12299..13219)
                     /locus_tag="ACG84X_001939"
     CDS             complement(12299..13219)
                     /locus_tag="ACG84X_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFP9127786.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            13345..14397
                     /locus_tag="ACG84X_001940"
     CDS             13345..14397
                     /locus_tag="ACG84X_001940"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFP9127787.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(14507..15262)
                     /gene="fabI"
                     /locus_tag="ACG84X_001941"
     CDS             complement(14507..15262)
                     /gene="fabI"
                     /locus_tag="ACG84X_001941"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFP9127788.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            15482..15922
                     /gene="fabZ"
                     /locus_tag="ACG84X_001942"
     CDS             15482..15922
                     /gene="fabZ"
                     /locus_tag="ACG84X_001942"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFP9127789.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(16037..16798)
                     /locus_tag="ACG84X_001943"
     CDS             complement(16037..16798)
                     /locus_tag="ACG84X_001943"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9127790.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            16987..18081
                     /locus_tag="ACG84X_001944"
     CDS             16987..18081
                     /locus_tag="ACG84X_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFP9127791.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         5922 a         3156 c         3843 g         5235 t
ORIGIN      
        1 cgagtgaaac aaattataaa cattaacaaa taattataat tgagcaaact tgacttatgt
       61 tttgtaagga ttatgctata ctctgggaag aggtgagtat gatggagcta acacagacag
      121 aattcgtttt atgccctaaa tttgaaaaaa cattctctat tttaggaaaa aaatggaacg
      181 gattgattat cgatgtacta ctcgaaaacg gtccgcaacg ctttgttgag cttgcggcaa
      241 aaatcccgat ggtcagtgat cgagtattag tcgaacgctt gaaggaatta gaaaaagaag
      301 gaatagtcac tcgaaacttt gcctgtagcg aaaagagccg ttcagaatat ctcttgactg
      361 aaaaaggagc agacttgcaa aaagcgatgc gtcaaataca agtttggagc gaaaaatgga
      421 tcacagagga agaatgcggt tgattttgta aaaaaaatct tgtaaactat agtccatacg
      481 aataagtaaa gaacgatgac gaaaaagagt agtttggcta aaccagttca gggagatctg
      541 tcgcagactg aaagcagatc ctgtgtttga aaaatgaagt tcactttccg agttcgtctg
      601 ataaaatcag accggcaatt gtcgttaacg aagtaagagt gcggtgtaag tcatttatcc
      661 gcaaattagg atggtaacgc gaagacctcg ttccttaaca ggaatgaggt ctttttgttt
      721 tgtatttgga atttaaagga ggaacaagca catgtctcta caagcacaat tagagagctt
      781 gaaagaagca acgctcgtca aaatcacagc ggcacaagat ttaaatgaat taaatcaaat
      841 acgtgttgaa acgttaggaa aaaaaggacc gatcacagaa gtattacgtg ggatgaaaga
      901 tctaagtcca gaagagcgac caaaagtcgg aagtttcgca aatgagatcc gagatctttt
      961 gacagaagag atcgagcgaa aaaaacaagt attagaagaa gaagcgttaa atgcagcttt
     1021 ggcaaaagaa acaatagacg tgacactacc tggtagaaaa gtaaaacatg gtacacgtca
     1081 tatcgtgaca caaatcatgg aagaaattga agatattttt gtgggtatgg gctatcagat
     1141 cgtagaagga tatgaagtag aatctgatca ttacaatttc gaacggatga atctgccaaa
     1201 agatcatcca gcaagggaca tgcaagatac tttctatatt tcagacgaga tattgattcg
     1261 gacacatact tcaccagtcc aagcacggac aatggaaaaa catgatttct ctaagggtgc
     1321 tctacgaatg atctcgccag ggaaagtctt ccgcagagat acagatgatg cgacccacag
     1381 tcatcagttc catcaaattg aagggctagt tgttgataaa aacatcacaa tgggcgacct
     1441 taaaggaaca ttagaagtcg taatgaaaaa aatgtttggg gaagatcgtg aaattcgttt
     1501 gcgtccaagt tatttcccat ttacggaacc atcagtagaa gtagatgtca gctgtttcaa
     1561 atgtggtggt gccggttgta acgtatgtaa atacactgga tggatcgaaa ttttaggagc
     1621 tggcatggta cacccgaatg tgttgaagat gtcaggaatc gatccagaag aatattcagg
     1681 ctttgctttc ggccttggac cagaccgcgt agctatgttg cggtatggag tgaatgatat
     1741 ccgtaatttc tatcaaaatg acttacgttt cttaagtcag ttcaaggggg agtaagaaaa
     1801 tgttagtttc atataaatgg ctcaatcgtt atgtagattt atcgaatgta acaccaaaag
     1861 aattagcgga taagatgtct gtgacaggaa tcgaagtaga gggagtaacg gttccagaag
     1921 aaggcttgaa aaaaatcgtt gtcggtgaag tcaaggaatg cgtaccacat ccagattctg
     1981 atcacctttc tatttgtcaa gtcgatattg gcgaagacga actgtctcaa atcgtttgtg
     2041 gagcgcctaa tgtgaaggtt ggaatcaaag tgattgttgc acttcctaac tcacgtatcg
     2101 ctggtaatgt aaaaatcaaa aaaggaaaaa tgcgtggcca agtatcaaat ggcatgattt
     2161 gctcattaca agaaattggc tattcagata gtgttatacc gaaagaatac gctgaaggta
     2221 tctattatat gccacaagaa gctgtaaatg gcgatccagt ttttccttat ttggatatgg
     2281 atgattcgat tattgaatta tctatcacac cgaatcgtgc ggatgcattg tcaatgcgtg
     2341 gcgtagctta tgaagttggg gcaatttatc gtcagactcc tacattcgat gacgaaaagc
     2401 tggtagaatc ctcacgtcct gctagcgata aaattcaagt ggaagttgaa gataaagaag
     2461 cagttcctgc ttatcaaatc agaatcattg aaggagtaag aatccagcca agtcctcaat
     2521 ggctgcaaaa tcttttgatg aacgaaggca ttcgtccaat caacaatgta gtagatgtga
     2581 cgaactatat tttgctttta ttcggacaac cactacatgc atttgactac gacaaattga
     2641 aatcaaaaga gatctttgtc cgccgtgcaa aagaaaatga aacattagta acactagatg
     2701 gagaatctcg ggaattgaca actgacaatc tcgtcattac taacggcaaa gaaccagttg
     2761 ctttagctgg tgtcatggga gggttagact cagagatcac gaatgaaaca acaacagttg
     2821 cactagaatc tgctttattt gatccaattt cgattcgtcg tacagcaaaa caatttaatt
     2881 tgcgtagtga atcctctgca cgttttgaaa aaggaatcaa ccatgcgact gttggagaag
     2941 ccagtgaggt tgctgcagca atgatcgttt ctcttgcggg tggggaagtt ctacaaggcg
     3001 cggtcaaagg ctcagagatc aaagcagaag acgtatcagt gaagatttca cttgaacgca
     3061 tcaatcaata tttaggaaca tctcttgtcg ttaaagaagt aaatgagatt tttgaagcac
     3121 ttggatttag ctatgaagaa aaggagtatg tttattccgt agtagtacca ccaagacgct
     3181 gggatatcca aatcgaagca gatattatcg aagaagttgc tcgtatttat ggatacgacc
     3241 agttgccatc tacacttcca agtggagaaa cggttgctgg aagcttgtca aaagaacaag
     3301 aaactactcg taaaattcgt acaatctttg aaggaagcgg attgagcgaa gcaatcagtt
     3361 atgcattgac aacagaagaa aaatcaagac agtttgttat aaatgaaagt aatattacac
     3421 gtttggactg gccaatgagc gaagaacgtt ctgtattacg aatgaatttg atcagcggac
     3481 tattagatga tatcagttat aacactgccc gaaaaaatac agagattgct ttatatgaaa
     3541 ttggtcgggt gttcttccaa gaaaatgatc cacgtacaca tctgccgcaa gaagtaaaac
     3601 atgcagcaat cgctatttct ggtatttggg aagaaaaaga ttggcagacg aaagctcaaa
     3661 atgtagactt tttcaccatc aagggtcttt tagaaaactt atttgaacaa ctaggcatca
     3721 ctgaagatgt ccattatcaa acagtgacag aaatgaagga aatgcatcct ggaagaactg
     3781 ctgcgattta ccttggcgaa aaatttattg gttttgtcgg tcaagtgcat ccaacgatta
     3841 caaaaagtta tgatattcca gaaacatatg ttgctgagtt tgatttatct gctatagtgg
     3901 aagctgctca aaaagggatc gttttcgaag cagtgacaaa attcccagca gtcagccggg
     3961 acatcgcttt gcttgtaaaa gaaactgtga caaatcagga attaacagaa gttatccgtt
     4021 ctgctgccgg aagattttta acagatatcc aattatttga tgtctatcaa ggagaaaaca
     4081 ttgaaaaagg acataaatcc atggcgtata gcctgacatt cgtcaaccca gaagcaacat
     4141 tgacagatga agaaatcaat aaagcaatgg aaaaagtcga aaaagcgttg gtagaaaacc
     4201 tagaggcaag tattcgctaa gaaggaaaat atagtaagta acgatcaagt agcttttgaa
     4261 gaccatacat ttgaaaaaaa gatgtgacac aacttcgtca catctctttt tttgatttta
     4321 aaaaaggaat agcacagaga cgagataaaa aaacaggcct ttacagcctg cttttttaga
     4381 gtaaatgaat taatggaagt aattgattcc cattgctgat tttacttcag aaagtgtttg
     4441 tgcagctact ttagcagctt cttcactacc tttacgtaag atttccataa cagctgaagg
     4501 atctttttcc aattcttctc ggcgcgcacg gatcggtgca aattcagctt ccaatacatc
     4561 aatgaggtat cgtttgatct ttacatcacc aagtccgccg cggcggtaat gagctttcat
     4621 ttcttcaatt gcttctttat ctgttccgaa tacatccaag taggtgaaga ccatattccc
     4681 ttctacttgt ccaggatctt gtacatggat gtggtttgga tcagtataca tactcatgac
     4741 ttttttctgt aagacatcgg caggatcgga gatataaata ccgtttccta acgatttact
     4801 cattttgcca tttccatcga ttccaggtaa tctacccatt ccttttggtg ggaatacgcc
     4861 ttttggttcc accaagactt caccatatgt atgattgaag ctttgtacga tttcctgtgt
     4921 ctgctctagc attggttttt gatcctcacc aacaggtaca agattcgctt tgaatgcagt
     4981 gatatctgct gcttgagaaa caggatagat aaagaatcct gtaggcacgc tttcaccgaa
     5041 ttttttttgt tcgatttctg ttttgacagt cggattgcgc cgaacgcgtc ctacgctgac
     5101 taagttcaaa taatacatgg ttaattcagc taattccgga atttgtgatt ggataaataa
     5161 agtagatttt gcaggatcta atcccacggc taaatagtct aaagcaactt gcaagacatt
     5221 tgatgaaacc ttctcaggat ttttagcatt atctgtcagt gcttgcatgt cagcaatcat
     5281 gacaaacagt tggttgtctt catctgcctg catagccact cgggttttta gagaaccgac
     5341 gtaatgccct aaatgcagct tcccagttgg tcgatctccc gttaaaataa tatttttcaa
     5401 aaaagacacc tctttacgat ttgtaagtct gagcacttaa tatcttaccg tttttcctga
     5461 aaagaaacaa cagttcctaa ggaaaaaaca aggaaagagg ataaaataac taatagatta
     5521 gaaatggaag aaatatttat gggagaataa acgttctaag aaactttaca aattactaaa
     5581 ctatcagata taatgtattt tattatacat ctttaaaaga aatcttacta aataataatg
     5641 ggagtgtaat tctatggcaa tgattaaatt tgatcacgtg gataaatatt atggcaagtt
     5701 ccacgcatta aaaaatatca atctcgaatt cgagaaagga gaagttgtcg ttgtcattgg
     5761 tccttctggt tcaggaaaga gcacgatgct tcgctgtatc aatggattag agacgatctc
     5821 ttcaggtaag ctgctgatta atgatactga cttgcatgat aaaaagacaa aactgacaga
     5881 agtccgaaaa aacatcggca tggttttcca acatttcaat ttgtacccaa ataaaactgt
     5941 tctggaaaac atcaaattag caccaatcaa agtgttgaag caagaccagg caactgcagt
     6001 caaaaacgcg gagaaatttt tgaaaactgt caatatgtta gataagaaag attcttatcc
     6061 ttccatgtta tccgggggac aacagcaacg ggtggcaatc gccagaggtt tagcgatgaa
     6121 tcctgagatg ctgctgtttg atgaacctac ttctgctttg gatccggaaa tgattggtga
     6181 tgtattagac gttatgaaaa aattggctca tgacggtatg tcaatgattg tcgtgacaca
     6241 tgaaatgggc tttgccaaag aagtggcgga tcgtgttatc ttcatggctg atggagaagt
     6301 attggaagac agcagaaatg tgagagactt tttcgaaaat ccaaatgaag tccgagcaca
     6361 gcaatttatc agtaaagtta tcaatcattg ataggaggaa aaagatgcgc aggttaaaaa
     6421 aaatacgcct gattttcctt ttaggcattg cttttcttgc actagccgga tgtaaaggaa
     6481 atgggttggc aaatgaagat attttagagc gaagcaaatc taccaatgaa atcatctggg
     6541 gtgtcaagta tgatactcga ttatttggaa tgatggatat tgagagcaga actgtacaag
     6601 gatttgatgt agatattgca aaagcaatca ctaaaaagat ccttggtgac aatggaaaaa
     6661 cagaatttgt tgaagtcact tctaaaactc ggattccatt attgaaaaac ggaaatatcg
     6721 atgcaattat tgcaacgatg acgatcacag atgaacgaaa aaaacaggtt gacttttcag
     6781 atgtctattt cgatgctggc caagctttgt tggtaaagaa aggaagccaa atcaaaagtg
     6841 tagatgattt gaatgcttct acaacggttc tagcagtcaa aggttctaca tcggctgcga
     6901 atatccgaca gcatgcacca gatgcaaaaa ttttagaatt agaaaactat gcagaagcat
     6961 ttactgcttt acaatctggt cagggagacg cgatgactac ggataatgcg attttgttag
     7021 ggattgcaga tgaaaatcca gagtatgagt tagttggtgg aacgtttact aatgagcctt
     7081 acgggattgc gatcaacaaa gggcaagaaa acttcttgaa agctgttaac caagcgctag
     7141 aggaaatgca tgcagatggc acatacgata aaatctatca aaaatggttt ccaaatgaaa
     7201 ctgaaggaaa agtagagtaa gggggagagg caatgagcga attgatacaa acttatggac
     7261 caatctttgt cgacgggttc aagatcacat tgttttcgag tgtcttagca cttgtgttta
     7321 gtttgattat cggaacgtta atggcaatct tccaattatc aaagaataaa gtagtgagcg
     7381 ccttagcaaa ggcatatgta gaatttttta gaaacattcc attattaatc atcgtgatgt
     7441 ttttttatgt tgtcgtaccg atttattggt ttaatctaga tggattccaa gcaggtacga
     7501 ttggattaac gatctataca tctgctttta ttgctgaaac agtacgttca gggattcaaa
     7561 ccgtaccaaa aggtcaaaca gaagcaggac tatcttctgg ttttacctat tcagaaatca
     7621 tgcgttatat tgttttaccg caagcattca aaatcgttat cccgccatta ggcaaccaat
     7681 ttatcaacct cgtaaaaaac tcatctattt tagcaatcgt agctggttta gatttgatgt
     7741 atcaaggaga cttgatcgct agtgaaacat tcaatacctt cgatacgtat atcatcgttg
     7801 ggttatttta cttagttatc acgctaccgt tatcttactt aatggtttat cttgagaaaa
     7861 aatgggcggt tcgttcatag aaggagggga aatacatgga ttttagcggc gctttttcat
     7921 ggatgaatat ccgtttttta ttggaaggat taaaggttac tgttgaagtt tcattgtttt
     7981 cgatcatttt tagtttcttg atcggtggtc tgacaggtgt gattcgtttt gcgaatatcc
     8041 ctttcttttc caaaatcctt ggtgtagtga ttgatattat acggaatctt ccattattat
     8101 tgatcatttt cttcacttac tttgccttac ctcaaatcgg cattcagatg aacatcttct
     8161 ggtccgctgt cgcagcatta acgatttttg agtcagctat gttgtcggaa attttccgag
     8221 ctggactcaa tgctgttcca aaaggacaga tggaagcagg attatcaacg ggactgactt
     8281 atgtagaatc gatgcgaacg atcgtgttac cgcaagcatt taaatcaatg atcccggcaa
     8341 ttgtgagcca attgatttca ctgatcaaag atacttcatt agcagtaatc atttctttac
     8401 ctgaactttc tcatcaggca cgtattattt atggacagaa caccaattat gtgcttccga
     8461 tgttcatcat catgacactt atgtacttcg tggtatgtta cgcgctttct ctgctttccg
     8521 gttacttgga aaagagacgg tacagttatt aatagatgat tcttttagcg gttgtggcaa
     8581 actaaagtca caaccgcttt tcctctttcc attcgaaaaa aagagatttc gattgtttta
     8641 agcaagtaag agcacttgaa aattcacgct aaaaagtaca caatagggag gatagaattt
     8701 attgaaaaaa aggatgatac gattgacaga taatcgccct atcggattta ttgattcagg
     8761 tgtcggcggc ttgactgtag taaaagaagc cctgaaacaa ttaccgaatg aaaatatttt
     8821 atttgtagga gacacagcac gctgcccata tggccctaga cccgcggaac aggtaatcca
     8881 gtatacttgg gaaatgacgg attatctggt ggagcaagga atcaagatgc tggtgatcgc
     8941 ctgcaatacc gcaactgcgg tggctttaga agaaatcaaa gctgctcttt ctattccagt
     9001 catcggtgtg atccttcccg gtactagagc ggcagtaaaa aaaacacaaa ataaacaagt
     9061 tggcattatc ggtacgattg gtacggtaaa aagtcaagct tatgaaaaag cactgaaaga
     9121 gaaagtacca gaattgactg tgacaagtct tgcttgtccc aaatttgttt cagttgtcga
     9181 aagtaatgaa taccattcat cggtggcgaa aaaaattgtg gcagaaacat tagctccttt
     9241 aaccactaaa aaaatcgata cattgatttt gggatgcacc cattatccat tattacgccc
     9301 catcattcaa aatgtaatgg gagaaaatgt tcaactgatc gattctggag cagaaacagt
     9361 aggtgaagta tctatgctgt tagattattt caatttgagc aattcaccgc aaaatggtcg
     9421 gacattatgc cagttttata caactggctc tgccaaactt ttcgaggaaa tagctgaaga
     9481 ctggcttgga atcggacact taaatgtaga acatatcgaa ttgggaggaa aataaggatg
     9541 cgtcatgacg ggagaaaagc ccaagagctt cgcaaactgg agcttcaaac aaatgttttc
     9601 aaatatccag aaggatcggt agtgatccgt tttggtgata caacagttat ttgttctgca
     9661 acaatagaaa attctgttcc cccttttttg agagaaacag gaacaggatg ggtgacagca
     9721 gaatatagta tgctgcctcg agcaacgagt acgagaaatc gtagagaaag cagcaaaggg
     9781 aaactttctg gtagaacaat ggaaatccag cgtcttattg gtcgttcctt gcgtgcagta
     9841 gtagacttgg aaaaattagg agaacgtagt atcatcgtag actgcgatgt gatccaagcg
     9901 gatggcggta ctagaacagc aagtatcact ggggcatttg tggcattgaa attagccatt
     9961 gaaaaacttt taagagaaaa agaattgtca gaagatccaa taaaagaaca tcttgctgca
    10021 gttagcgtag gaatcttacc agatgggact tgcgtcacag atttggatta ccaagaagat
    10081 tccgcagcac ttgtagacat gaatcttgta atgacagaat ctggaaaatt cgtggagatt
    10141 caaggaactg gagaagaagc aacgtttgat ggtgaacagt tgaatgaaat gctctttttt
    10201 ggaaaaaacg cgattgaaga tttgatcaaa gagcaaaaac atgctttgct aacagagttt
    10261 gctcaaaatg atgagcggat agaagaaaca aaaacaatca tcattgcgac aagaaatcca
    10321 ggaaaagcag aagagtttcg aaatatgttc aaagaagcgg gatatcatgt aaaaacatta
    10381 cttgactatc ctgaattgcc agatgtggaa gaaactggca gcacatttga agaaaatgcc
    10441 cgattaaaag cagaaacgat tgcacaattg cttgatcagc cagtcttagc agatgattca
    10501 ggtttgaaag tggatgcttt aggcggtatg ccaggaatct attctgcacg ttttgcaggg
    10561 gaacaaaaaa gtgatgcggg gaataacgcc aaattattat atgaattgac agatgtgccg
    10621 gatgaaaaaa gaacagcaca attccattgt acgttagtat tcgcggcacc caaaaaagac
    10681 agccttgtag tagaagcgga atggcccggt cgagtagccc gtataccatc tggcgaaaat
    10741 ggctttgggt atgatccttt atttatccca gaaggtaaga aacaaacagc agcagaatta
    10801 tcgagcgaag aaaaaaacaa gatcagtcat cgggctcaag caatgaaaaa attgagtgcc
    10861 gagtggaaac aatggctgga aggagagaga tagatgcggt atttagtagt aagtgataat
    10921 catggagaca gagatatcct cgttgactta gtagatcgtt atcgttctga agtggatatc
    10981 tttttccatt gtggtgattc ggaattagaa gcttctgacc cattatggga tacattccaa
    11041 gtggttcaag gtaattgtga ttatggacca ggattcgaac agaaaaaagt gatccaaact
    11101 ggtcaggata cagtattcat gactcacggt catttatcga atgtccgatt tggtttgaca
    11161 cagttagcaa tcgaagctcg agctgcaact gccgatatgg tgttttttgg tcatacccat
    11221 caaataggct gtgagatgga tcagaaaatc ctgtttttga atcctggtag catttctcag
    11281 cctagaggcc cgatccaaat cccatcatat gctcttatcg aaagtttaga tgaccaaatt
    11341 tctgttcaat actataaccg tgcccatcag gcagttgaag agttggcctt ttctttttcg
    11401 agagagcgct gaataaaaaa actctaattt ttaataaaaa taagctttat tttatgaatt
    11461 ttgcatccgg tttcggtaaa atagtagtgt tgaatgaaat agaaatggag gccatcagat
    11521 gattggacct atagtaagag aaatgctgct ggaaaatcag gaaacgtttt tgattcctgc
    11581 agaaaatgtg gcaaatgtta tgtatcatca tccattgtcc catggtttac ttgtgttatc
    11641 gaaggtcggt tattccaaaa ttcctgtatt aggaaaagat gatcactttg taggactagt
    11701 aagtttatca gatgtggtca ataaaatgat tgacttgcaa acaatcagca tggacccgtt
    11761 agaaggacta acggttgctg atgtgacaga aacagatgtt ccgacaattg atgaaaattg
    11821 ggaactagaa gaagtactcc atttgttagt cgattcgcct tttttaccgg ttgtcacaga
    11881 agatcggatt ttcaaaggaa tcattacaag aaaagagctg cttaaagccg taaacttcat
    11941 ggtgcatgaa ttagaacgtc gtaatatatt gtctccgaaa atcgaagaat taaaagaaca
    12001 aatcgatatc gtgagctaaa gaacgagaaa ctaaaagata atcaaaaaat aagtagaaaa
    12061 aacagcgtac cagttttgac tttatcttga aaaagaggct gggacaaaag cgtttaactc
    12121 caagaaataa gaaggaattc acgaaaattg cttttcaaat ttttgtgaat ttcagcttat
    12181 ttccgaagga gttgcttctg cttccgccgt ttatacgtgt ttagagcgtg ggacaaaagt
    12241 gttctttact tttgtcccac gctcttttta gtgagattcg ttgcatcgtt tgtccaaatt
    12301 attttccgac agcaattgga ctgttcggaa tcgtgaaacc agaagctgtc aattctttga
    12361 cataggagct caagaactct tcttttaagg catattgttt tccgttcaat gcgtagcaga
    12421 ccgtacgaat cgcaaaattg ctgtttccaa gatccactaa tccaaagata gaaggttcag
    12481 tttggagctc ttcttggtat ttttcagcta atgtacgatt tactcgatca atgatctcat
    12541 agattttgtc atatccttct tcaggaacaa tccgaatatc taaaagtact tgcatatttg
    12601 cacgagagag attgctgatc gtggtgatgt ttcgattcgg gatgaaatgg acagtaccat
    12661 ccgttgcttt cagctgaagg gtacggatac caacagatac gacggttcct tcaatcgtta
    12721 agtttgctag cttgatgtag tccccaacat ccatctgttg ttccatgata ataaaaaatc
    12781 cggtaataac atcactcatg aacccttggg caccaagacc gattgccaca cctgcaattc
    12841 cggcaccagc caaaagtgat ccgatcggca caccgatagc agataaaatt gcatagataa
    12901 aaaagaaacc aagggtataa tgaaaaatag tatttaaaag actatgtaaa gtctttaagc
    12961 ggctctcgtt tagaatggct tttttagaat actgattaaa agacttatca atcagatatt
    13021 ttcccacacg gtgaagaatc caaaaaagga cgatcaaaaa aatcagatat aaactttttt
    13081 ggataaaggc agccaaaatg gcgtcccaat caatcccgtc ccaaaaccgc tgaaacgcat
    13141 ttactttgct gacagcttga tctgtcaatg tctcgccaga agagtctgtc gtaccggcag
    13201 ttgctaataa tgaaaacata aaatcctctt ttctaaaatt tgattctttc tgtattgtac
    13261 caagaagttt tcaaaaaagg aaatagcaaa aataactata atgaaggaaa aaagctgaaa
    13321 ataaaatgac aaataatatg gataatgata aaatgtggag aaaataacga aggtggtaag
    13381 tatatgcaaa tcgattggaa caatctaggt ttttcttata tcaaaactcc ttggcgtttt
    13441 attgccaaat ggaaagacgg acaatgggaa gaaggagaat tgacagaaga taattacctg
    13501 acgattcatg aaggctctcc agcgcttcat tatggtcagc aatgttttga aggtctaaaa
    13561 gcttatcgtc gaaaagacgg caaggtcaat ctctttcgac ctgaacaaaa tagtcgacgg
    13621 atgaatcaaa gtgctagacg attgctgatg ccaatggtcc ctgaaaagat gttcgttgat
    13681 gctgtcaagc aagtggtaaa agcaaatgaa gattttgtgc cgccctatgg aacaggcgct
    13741 acattatact tgcgcccttt actgattggg gtcggtgaaa acattggtgt ccatccagct
    13801 ccagaatatt tatttgtcgt cttctgtacg ccagtaggag cgtatttcaa aggtggacta
    13861 aaaccaacga attttattgt atctgattac gatcgtgctg ctcctaaggg gactggtgca
    13921 gcaaaagtcg gcggaaatta cgcagcgagt ttacttccag gaacagaagc aaaagaactg
    13981 gattactcag attgtgttta tcttgatcca gccacacata cgaaaatcga agaagtaggt
    14041 gcagcaaatt tctttggaat tacaaaagac ggaaaattca tcactccgca atcgccctct
    14101 atcttaccaa gtatcacgaa atattccttg ttgcagttag ctgaagaacg actaggactg
    14161 caagcaattg aaggagatat tttcattgat gatctagatc aatttgcaga agctggtgca
    14221 tgtggtacag cggctgttat ttctccaatc ggtgggattt atcacaataa caatcttcat
    14281 gtattttata gtgaaacgga agtaggacca gtaacaaaac ggttgtatga tgaattgaca
    14341 ggtattcaat ttggagacat agaagcacca gaaggctgga ttgaagtcgt ggaataattt
    14401 caaagtaatg agttgaaaaa aacgtaaaaa gaaaaaatca ggaagagact ttaaaaagtt
    14461 ttttcctgat ttttatatgt tttactttaa agaatgcaac aaaagtttat gaaagatgga
    14521 cacctttgtc aacgtagata atatcaccga tgattccgct ggaaagtggg ctgattaaga
    14581 aagcacaagc attaccgact tcttcgatcg tcacaccttg ctgatcaggc gtacgagatt
    14641 cagataactg gatcagtttt tgatagtctt taacacctgt gacagctaat gttttgattg
    14701 ccccagctga gattccattg acccgaattc ctttaggcga gaactcagct gccaaataac
    14761 ggatagcagc ttcaagagaa gctttcgcaa tacccatcat gttataattc gggattgcgc
    14821 gttctgaacc tagataagtc atgctaacga tcccgctgtt tggtgcaaga aacggttgtg
    14881 cgtattttga tacagcaatt aaagagtagc tgctgatatc ttgagctaat tgatagccgt
    14941 ctctggaaat atcagacaca tttccggaca attcttcttt gttggcgtaa gcaactgcat
    15001 ggacaaggcc gtggatctcc ccagcatatt caccgatggc attcattgct ttttcgatgc
    15061 tttcgtcgct agaaacatca cattctacag tgaatgcttc ttcgccgacc aatttgacta
    15121 atgatttttt cattcgttca ttttggtaag tatagataat ttctgcccct tgtttcaaca
    15181 ttgcttcagc acaaccccaa gcaatgcttt ttttgttagc gacgcccata atgacgattt
    15241 tttttccttc tagaaatgac ataatgactc tcctttgttt ctgataaaaa tttgatagtc
    15301 gtaaaaaaat agagaataat agctaaaata acttcttgat ttcttaatta ttagtcaaaa
    15361 tgttttgatt gtcaaactat tttttcttaa attaaaaaaa gattgctaaa tatttaggaa
    15421 tatgatactt tgatagtcaa agtaatgaaa atggcaattg cctgaaagaa ggagtttaat
    15481 tatgtcttac gtattatctg ctactgaagt aatggaattg attcctaatc gttatcctat
    15541 ttgttatatt gattatgtag atactttaga accaggaaaa aagatcgttg cgacaaaaaa
    15601 tgtaacaatc aatgaagatt ttttccaagg tcactttcct gacaatccag tgatgccggg
    15661 tgcgttgatt ctagaaacac tggcacaagc aggttcgata cttatcctaa aatcagaaga
    15721 gtttctagga aaaagagctt atatcggtgg gatcaataag gccaaattcc gtcaaaaagt
    15781 tgttccagga gatgtgctga aatgtcattt tgaaatcacc aaaatgaagg gatcagtcgg
    15841 tacagcgtta tctgcagcat atgtagatga taaaaaagtc tgtgagtgcg agttcacgtt
    15901 catcgtcaac caaaatgctt gactataaaa cctgatatag caaaacaaaa ggaagcttac
    15961 ttgcttttta tgtaaaaaga agacgcctga atcctagcat acgttgtcat ctatgcagga
    16021 ttcagacgtt atttttttat ttttgttttg cttcttgcag tatattgatt ttatcgattt
    16081 ttacttcttc ttttggtttg tctgaactat ctgtttcgat atttgcaata gcatccacga
    16141 catccattcc ttcaatcact tggccgaaga cagtataatg gccatctagt gaaggataac
    16201 cgccgttttt ataagcgtcg atgattgctt gaggatagtc gtcttttaaa agaccatcat
    16261 gcatatcatc tgtattttga acgataaaga actggctgcc gttactgtta ggatcttgtg
    16321 agcgagccat agataacgca cctcttatat tataaaggtg gttgttgatc tctgtttcaa
    16381 atccttctcc ccaaatgctt tcccctccag tgccatcgcc tttaggatcg ccaccttgga
    16441 tcatgaaatc tttgatgacg cgatggaaag tcagtccgtt gtagtaaccg tcttttgcat
    16501 gtgtcataaa gttttcaacc gcttttggtg cgtgttcggg aaataatttg attttgattg
    16561 tgcctttatt cgtcaccatt tcgaccagat cttcattttc ggcgacatct ttcgtcaatt
    16621 gtggtaattc caatgcgttc aaatcgacgc tactggcagt cgtgctttcc gcagtagatg
    16681 tactttttga actttctgta gacgaactag aagaagtcgt gttgtttgca gaacaaccag
    16741 cagcaaacag caatgctgct gctaaactaa tacttaaaat aactttattt ttcttcataa
    16801 ctgttccttt ccaatttact attttgttat ctttaatgat aacaaaatag agggaaaata
    16861 cctacttaaa ttattggaat ttatcattta ttttaaaaga aaaagaaaag gtgtagacca
    16921 tttactttgt gtttgctata atgtaagtgg atacaaaaac gaaaagatgc aggaggaaat
    16981 ggtaatatgg gaaaattagg aatctcgatt tatccagaac ggtcaacatt tgaaaaggac
    17041 aaagcgtact tggatttagc tcataagtat gggtataaac gggtttttac cagtttgctg
    17101 cagatcaatg atgataaaga aaaagttctt tcagaattta aagaagtagt tgattacgcg
    17161 aatagcctag gcatggaagt aatggttgat atcaatccag cgttatttga acagttggag
    17221 atttcttacg atgacttatc ttttttccat aagatgggtg cctacggggt ccgcttagat
    17281 atcggattca caggagcaga agaagcaaaa atgacgcgca atccttttgg tatcaaaatc
    17341 gagatcaata tgagttcggg cacgaattac gttgacaaca tcatgagtta ttcgccaaac
    17401 acggataatt tattaggttc tcataatttt tatcctcatc gatactctgg tttaggatac
    17461 gaacactttg ttttttgttc agaaaaattc agaaaatata atttgaatac gatggcattc
    17521 gtcaattcgc aatctgctga gtttggccct tggcctacgc aagatggctt gtgcacgctg
    17581 gaagaccacc gagatcttga aattgcgaca caagtgaagc atttaatcct tacaggattg
    17641 attgatgata tttctattgg aaatgcgtac gcaagtgaag aagaattgaa agaaatggca
    17701 gaagcattta acgcggatta tccaacattg aaagtagata cggaagaagg tattacagaa
    17761 aacgaacgaa tctgcttgtt tgataacctt catagttatc gaggggatcg ctcagaatat
    17821 atccttcgtt caacgatgac tcgtgtatac tacaaagata aagatttccc gcctcataat
    17881 acgcgagata tgcatcatgg ggatgtactg attgacaatg aagggtacgg tcaatacaaa
    17941 ggagaaacac aaatcgcctt gaaggatatg aaaaacgacg gacgtgtcaa tgttgtagga
    18001 agaatctccg atgacgaatt attcctcctt gactttttga aaccatggtc aagctttaaa
    18061 ttaattgaaa ataaaaaata gataattagt tattgcagaa ataatccgct agaaatagcc
    18121 agttatttct gcttttttat tttgtttttt tatagg
//
LOCUS       DAZKCH010000056        17930 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000056 DAZKCH010000000
VERSION     DAZKCH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.056"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..961)
                     /gene="murB"
                     /locus_tag="ACG84X_001945"
     CDS             complement(26..961)
                     /gene="murB"
                     /locus_tag="ACG84X_001945"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFP9127792.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1034..1954)
                     /locus_tag="ACG84X_001946"
     CDS             complement(1034..1954)
                     /locus_tag="ACG84X_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9127793.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2067..2819
                     /locus_tag="ACG84X_001947"
     CDS             2067..2819
                     /locus_tag="ACG84X_001947"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFP9127794.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3683..4216
                     /locus_tag="ACG84X_001948"
     CDS             3683..4216
                     /locus_tag="ACG84X_001948"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFP9127795.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(4706..5230)
                     /locus_tag="ACG84X_001949"
     CDS             complement(4706..5230)
                     /locus_tag="ACG84X_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFP9127796.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(5223..5696)
                     /gene="tsaE"
                     /locus_tag="ACG84X_001950"
     CDS             complement(5223..5696)
                     /gene="tsaE"
                     /locus_tag="ACG84X_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFP9127797.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(5819..6799)
                     /gene="pta"
                     /locus_tag="ACG84X_001951"
     CDS             complement(5819..6799)
                     /gene="pta"
                     /locus_tag="ACG84X_001951"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFP9127798.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(6952..7632)
                     /locus_tag="ACG84X_001952"
     CDS             complement(6952..7632)
                     /locus_tag="ACG84X_001952"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFP9127799.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            7758..8627
                     /locus_tag="ACG84X_001953"
     CDS             7758..8627
                     /locus_tag="ACG84X_001953"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9127800.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            8653..9168
                     /locus_tag="ACG84X_001954"
     CDS             8653..9168
                     /locus_tag="ACG84X_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFP9127801.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(9215..9778)
                     /locus_tag="ACG84X_001955"
     CDS             complement(9215..9778)
                     /locus_tag="ACG84X_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9127802.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(9833..10012)
                     /locus_tag="ACG84X_001956"
     CDS             complement(9833..10012)
                     /locus_tag="ACG84X_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127803.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(10089..10598)
                     /locus_tag="ACG84X_001957"
     CDS             complement(10089..10598)
                     /locus_tag="ACG84X_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127804.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(10694..11074)
                     /locus_tag="ACG84X_001958"
     CDS             complement(10694..11074)
                     /locus_tag="ACG84X_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9127805.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            11404..12153
                     /gene="pnuC"
                     /locus_tag="ACG84X_001959"
     CDS             11404..12153
                     /gene="pnuC"
                     /locus_tag="ACG84X_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFP9127806.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(12474..13691)
                     /locus_tag="ACG84X_001960"
     CDS             complement(12474..13691)
                     /locus_tag="ACG84X_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFP9127807.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(13949..15226)
                     /locus_tag="ACG84X_001961"
     CDS             complement(13949..15226)
                     /locus_tag="ACG84X_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127808.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15305..15949)
                     /gene="pcp"
                     /locus_tag="ACG84X_001962"
     CDS             complement(15305..15949)
                     /gene="pcp"
                     /locus_tag="ACG84X_001962"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFP9127809.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16148..17092)
                     /locus_tag="ACG84X_001963"
     CDS             complement(16148..17092)
                     /locus_tag="ACG84X_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFP9127810.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17094..17780)
                     /locus_tag="ACG84X_001964"
     CDS             complement(17094..17780)
                     /locus_tag="ACG84X_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFP9127811.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         5149 a         3676 c         3221 g         5884 t
ORIGIN      
        1 tacttatttt aagttccatt acttattaat tggctaaact tctgcttgtt tctgatattg
       61 cttgtttttc tccaatgatc cgcacttctg tttctaaaga cacatcaaat ttttctttga
      121 ttacttcttg gatgtgcgca atcaattcaa tataatctgt cgctgtcgca tgatcgatat
      181 tgacgatgaa tccagcatgt ttttcagaga cttgtgcacc gccccatttc aggccttgca
      241 atcctgcttg ttggatcagc tgacctgtat agtgtcctac tgggcgctta aagacacttc
      301 cgcatgaagg gtattctaat ggctgttttg attgacgcaa ttcggtcaac tcatccattc
      361 ttgctttgat tgcttcataa tcccctgttt gcaaactgaa tcgagcttcc aatacgatag
      421 cacgtaattc ttggacttta ctgtgacgat aagaaaatac catttcgtct tttgtcaaag
      481 ttttcaatgt tccatcttca agcaaaagat ccacttcagc aaaaacatct ttgatctctc
      541 cgccatacgc acctgcattc atataaaccg ctccaccgac acttcccggg atgccgcaag
      601 caaattcaaa tccagtcaat gattctgcca aagctgcata agtcgtatca atcagtgagg
      661 cacctgcttc cgcaatgacc atcgttcctt tgacatgaat ctgtttcatt tcagtcagca
      721 tgatgactac accgcgaatc ccgccatctt gaacgatcag attgcttgca tttcctaata
      781 ccatccaagg tatatcatgg attcggcaat aatcgatgat ttgctttact tcttcttgtt
      841 ttttcgggaa tgcaaggaca tcagctggtc cacctgtttt cgtaaacgta tagttcatca
      901 atggttcatc aaacaatata gtaatcgtgg ctaagctttc aactatttct tctttattca
      961 ctgaggattt tcctttcttt tctcaaacgt cctcattatt ctatcacgct taatacaatc
     1021 ttgccagtct tgttcaaagt tgatgacggt agtgatcttt aagcacttcc tcacataatt
     1081 catgacttct tacaacttct ttttgtttaa gcaattctgt ttccgattta cctaaacgga
     1141 tctgagaaaa gaaggcctct accattggct caaacccgcg tttgactagc gtgtttgtcc
     1201 agtcgccaaa ttctttcact ttttttccat cagcatcttg aatgacaagc tgggtcagat
     1261 cgtttacttc ataagtacca tttttacttg ttacttgata tttttctata ttagcgccac
     1321 ttgctaaatc catcgttaaa atagccgttt gattttgtgt ttctaattgt aaaatggcat
     1381 attccaaaaa ttcctttgtt tctcttatct ggtattttgt tctcaaaatg ggttcatcta
     1441 ataaatacac agctgtatca ataagatgta aaaacaaatc ataaaggacg aactctgtcg
     1501 tttcttttgc cgctattcga tttttttgca ggtggatcaa ccgcttatct gggatacgtt
     1561 tcaattcttc taccatagga gcaaagcgcc ggttgaaacc gatcatcaaa attatttggt
     1621 tcttatcagc taattcttgc aattcacgaa cttcatttag atggacactc agtggtttgt
     1681 caatataaac atggatacca ttttctagac attttttggc taattcataa tgtacttttg
     1741 ttgctgcgtg gatcatacat gcttcgattt tttcttctaa aagctcatcg atcgtttcat
     1801 atagatgttg gaacccgtac tctttttgaa ttctttcttt tgtttcttta tttcttgttg
     1861 caaaataaaa atcaagtgtt ccttgttttt tcgcataagt tggtaaatat gctttttctg
     1921 cgatattccc tacaccgatt acaccaatct tcatctactt tcctcctgga tcatttagtt
     1981 actttcatct tacaccattt tttactaaaa tgaggtacaa tagtatcgca aaggtaagga
     2041 aattaattcg aaggagtgtg cttttattga aatttatctc ttggaacgta aacgggcttc
     2101 gtgccatcgt aaataaaaat tttttagaag tttttcatga gttagacgcc gattttttct
     2161 gtctgcagga aacgaaactc caagcaggac aaattgattt agatcttcca ggttattatc
     2221 aatattggaa ttacgcggaa cgaaaaggct attccggcac agcgattttt gctaaaaaac
     2281 cagcattgaa tgccacttac ggaatgggta tcgatatcca tgatacagaa ggccgtctga
     2341 ttactttgga atattccgat ttctttcttg taacctgtta cacgccaaat tctcaaagcg
     2401 aattaaaacg tttagattac cgattagaat gggaagaagc cttttataat tatttggaaa
     2461 atctaaaaaa acaaaaacca gtcatcgtgt gtggggatct aaatgtcgct catcaaaaga
     2521 ttgatttgaa aaactggaaa acgaatcaaa aaaatgctgg attcactcca gaagaaagag
     2581 cggctctttc tcgactgttg gataacgggt ttatcgatac attccgttat ttttatccaa
     2641 cccaggaagg tgtctactct tggtggaact accgattcaa ttcaaggaaa aacaatgctg
     2701 gttggcggat cgattacttt ttgacgagca aagatttaga gccaggacta gctgatgcaa
     2761 agatccatac ggacattatg ggcagtgatc attgtccagt agaattagat ttgaaataaa
     2821 gaggttgtga aaaagtcgtt tagtttcgag tattaagaaa aattttgtga aaatggcttt
     2881 ccacattttg cataaatttg gcataatacc gagaaactgg cttttgaaca ctgtttatcg
     2941 agagattgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc
     3001 ctcatatttt tcgtttggtt gggcttatta ccgcagatac aagcttttga acaccgttta
     3061 ttaagaggtt gtgaaaaagc tgcactgcat caagtaataa gaacagccaa acaaaaatag
     3121 ttcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
     3181 ttattaagag gttgtgaaaa agctgcactg catcaagtaa taagaacagc caaacaaaaa
     3241 tagttcctca tatttttcgt ttggttggac ttattaccgc agatgcaagc ttttgaacac
     3301 cgtttattga gaagttgtga aatcagcgtc ctgacctgag tattagagaa acaaatggca
     3361 aaatagttcc tcatattttg ctattttttg agctaatacc gagggtcagc tgattgaaca
     3421 ccgtttagtg gagaagttgt gaaaaagtcg cctactttcg agtcgtaaga aatttttttg
     3481 aaaatggttc ctcacaactt tgcataaatt tgacttaata ccgagaagtc atgatcccca
     3541 tctaactcca aatcacaagg aatgagttca aaaactagct tttctcaaca aatattacat
     3601 aaaaaattct atgttttttg ttaaatttat ttgctttttt caaaagtatg ttacagtaat
     3661 ttcccaagga ggttttacag aaatgaattt tgttgccatg gattttgaaa ctgccaatca
     3721 tcagccttat agtgcttgtt ctcttgcgct agtcatggta aaaaatagcc agatcgttga
     3781 tgaattctat acattgatac agcctgagac tccttttttc tggcgaaatg tccaaattca
     3841 cggaatccat caagaagacg tacgcaatgc gccgaaattc ccagaagtct ggcaaactat
     3901 ccaaccatat tttcaaaaaa atcgtttagt cgttgcacat aatgctgctt ttgatacaaa
     3961 ggtcttagcg ggatgcttag attattatca tcttgaacag cctaattatc tttctttatg
     4021 tacagtgaaa agtagccgtc gcctgtttcc tgaatttcca aatcatcgat tgaacactgt
     4081 gtgcgaaaat ttgaacatcc aattagatca tcaccatgat gcattggaag atagtcgtgc
     4141 atgtgcggaa atcctgcttt atcaagaaaa aaaattcggg acagatccat tgaaaaaact
     4201 tgtgactata aagtaaaaga atacttatga aacacacaaa gaggtcgtga gcctgccgtt
     4261 tcactccgag tcacaaggag caatttcaaa aaatagcttc tcatgtttat taaatattgt
     4321 gactggtgac cgaggagctg gcaggagaac accgtttatt ggagaggttg tgaaaaagct
     4381 gttctgcatc aagtaataag aacagccaaa caaaaatagc ttctcatatt tttcatttgg
     4441 ttggacttat taccgcagat gcaagctttt ggacaccgtt taccaagagg ttgtgaaatc
     4501 agcgttttga cctgagtatt agagaaacaa acggcaaaat agttcctcat attttgccgt
     4561 tttttgagct aataccgaag gtcagctgat tgaacaccgt ttattcaaaa aaaatggact
     4621 gcgacacgac ttttgtcaca gtcccttcgt gtgtttttct gccttctcaa aaggatgaca
     4681 gtttctcact cttttcctat ttcttctatt caatcaaata actcatttta tatacatcta
     4741 aaaattcacc tagatctgtt cttgcccctc taggcatgac cgcttcgatt tggaagccca
     4801 tttttcggta aaggtgtacg gctctttcat tacgaacttg aacgtcaagc tccaatcgaa
     4861 aaagtacacc catttccttc gcccaactga tgatttcttc tagcataaga gtgcctagtc
     4921 ccattcccca atattcctgc agaatactga taccgacttc tcccacgtga gacaaacgaa
     4981 attgactgtc tgccttgaca gatgctgttc caataatcgt cccttcatag attgcaagca
     5041 gcaataaatt attattgctt tcgtatatat aatccaactc ttcttctaag gtttctggtg
     5101 gtaacaggag ttctgcttca tccaaaacta aaaattctgt ctccttatta acttgtccca
     5161 tcatcaaaag aatgtctttt gcatctcctg gcactgcttc ccgcaagatg atcccaactt
     5221 cttcactcat gattttcagc ccatttttct agaattcgct gtttgaaggt ttcactttgc
     5281 tccccgtatg agattagttt cacataccgc ttttctaaat ctgtatcact tttttctaaa
     5341 atcagttcca aataatcctc cggcagtgct tcttctaata gatttcccca ttcaacaacg
     5401 gaaagcccat caccttcaaa atattcatct aaccctaaat ctgctccgct agctgctacc
     5461 cgataaatat ccatatgata caacggaatc cgaccttgac tatattctct aataatcgtg
     5521 tatgtcggac ttttgatcat ttgcgttatc cctaatcctt gggcaattcc tttcgtcaac
     5581 gttgttttac ccgcacctag atcaccagtc aatatcagat tgtcacctgg cattgcggaa
     5641 tgaccaattg cctctgcgaa ttgttctgtc attgttaatc ctgatagttc gatcattttt
     5701 catcttctcc cgctcttctt tctttttgcc agtatatcgc gtaatgaagt ttttttaaag
     5761 aaaaaatgaa ctagtcaaga acagcagctg ctgtttttgg ctagttcgcg tgtatttgtt
     5821 aatcaatcaa tgtttgtgct gctgtgataa tcgataattt atatacatct tcttcatttg
     5881 ctccacgaga caaatcagaa accggtttgt tcaagccttg tagaattggt ccgattgctt
     5941 caaagttacc gaaacgctga gcaattttat agccgatatt tcctgactgc aattctggaa
     6001 atacaaagac tgttgcttga ccagctactt ctgaatctgg cgctttcagt tgtgcaactg
     6061 aaggaacata agaagcatca aattgcaatt cgccgtcgat catgtattgt ggcgctagtt
     6121 ttttagcgat tttagttgct tcaactactt tgtctacttc tggcgatttc gctgagcctt
     6181 ttgtcgagaa gctcatcatt gctacttttg gttcgatatc gaacaattct gctgtttttg
     6241 cagaatctac ggcgatttca gccaattctt gcgcagttgg attcacgttg atcgcacaat
     6301 ccgaaaagac atatttttct tgatctcttc cacgtaccat gatcatcgct ccgcttgtcc
     6361 gactgatgcc aggctttgtt ttgatgatct gaagtgctgg gcgaacagtg tcgccagtcg
     6421 aatggatcgc tccagagacc attccgtctg caatccccat atacgtaagc atcgtaccaa
     6481 agtaattcac atcttttaaa atcttttctg cttgttcttt ggatgccttt ccatttctac
     6541 gttcaacaaa agtatccacc atttcatccc acttatcgta attatcaggg ctgatgatcg
     6601 taaagctaga tgttttgatt cctctggcat gcgctgcatt tcttatttct tcttcgttcc
     6661 ctactaaaat gggttccaca agttcttctg ctttcaaccg ggcagctgcg cctaaaatac
     6721 gagcatcagt agcttccggg aaaacgattt tgatcccacg gcgaacaatt ttaaatctta
     6781 aactatcaaa caattccaca agatgacctc cagacgtttt tatatgtatt atcatacact
     6841 attccagaaa aaaagaacag tttattttat ctgtatcagt caaaaatgct ggaaaaatta
     6901 agtttttcac atacaaagcg aactgcacta taacaggaaa gcgctgtttt attacactgt
     6961 ttcaggcagt tgccaatcaa tcggttcttc tcctaacgca aggagcgcat cattcgtttt
     7021 cgagaagggt ttggaaccaa aaaagccacg acttgcagat aacggactgg gatgtggaga
     7081 tgttatgatg atatggcgac tcttatcgat cattttgatt ttttcttgtg ccggttttcc
     7141 ccacaagata aacacgattg gtttttcccg ttcatttaat ttttcaatga tcgtgtctgt
     7201 taatctttcc caacctttcc cgcgatgaga atacgcttgc ccttcccgaa cggtaagaac
     7261 ggtgttgagt aaaaggactc cctgtttagc ccatgacact agatttccat gttgaacagg
     7321 tgcgattcca agatcatcat aaagctcttt atagatattt cttaacgatg gcgggatctt
     7381 tacgccaggt tgcacagaaa aagataagcc atgagcttga ttttctccat gataaggatc
     7441 ttgtcctaaa atcaccactt taacttcttc ataaggagtc aattccaatg cttcatagat
     7501 atgatacata tctggatgga tcttttggga cgcatattct ttttttaaaa attctcttag
     7561 atgcagataa taatcttttg aaaattctga ggacaaaact tcttgccaac tgttatgaat
     7621 gatttctttc aaaaactcca cctcctaata aaaagaataa ctcacatttt cttcaatcac
     7681 aagggacaat cttcaccctc agcacttgat taatatggta aactaggaac aagaagcaga
     7741 aaggaacgtt aatcattatg atcaaattaa ttgcatcaga tatggacggc acattattag
     7801 atgcccatat gagtgtttct cctgaaaatg ccgaggcgat acgttttgca aatgatgccg
     7861 gtgttgagtt catggtcgct actggtcgaa actatcaaga agctcgcgca gctttagatg
     7921 aggtaggaat cgattgtgcg atgatcactt tgaacggggc acaggtattt gataaagaag
     7981 gaaattcatt gtttaccgtg tcgattccaa ataatcaagc aatctctgtt ttagatattc
     8041 tagatgctaa cggtatttac tatgaagtag caaccaacga tggtctttat tctgaaaatc
     8101 aagcgaaacg aattgaaagt tttgcttcca tggtggctac ccatttacct caccttacgt
     8161 ataaaatggc gattgccatg gcctcagcta agctggagtt attgcacatc acatacgtgg
     8221 acagtattcg tgctattttg gaagaaaaga atctggaagt tttaaaaatt atttgttttc
     8281 atacagaagg gccagctgta ttaggtccag ttggaaagca gatttctctt ttaggcgatc
     8341 tagccgttac ttcctctggt caaaacaata tcgaagtgaa ccataaaaac gctcaaaaag
     8401 gaattgctgt tgcccatgtc gctcacgagc gtgggatttc tttagaagaa gtcatgacga
     8461 ttggcgataa cttcaatgat gtcagcatgc tgcaagtagc aggagtcagt ttcgcaatgg
     8521 gaaatgcaga aatcgaagta aaagattatg ccaaatatac aacggacaca aaccttgaat
     8581 ctggcgtagg aaaagccata ttgcgcgcga ttgcagaaga cttgtagttt tatctagaaa
     8641 agagggatat agatgtcaga atttttcatt caggaaaagc agcttggacg tgcaactcgg
     8701 acaattgtca aaaacgaaaa aggacattcc ctgtttttga tggttggtcg ctggggaaca
     8761 aagggcgatg cattgtctct ttatgccatg aatggcgatc tcgttgctca catcaagcag
     8821 ataagcctga cattcggtac gcgttttgag ctgtataaag agttcgaaaa ggtgggaacc
     8881 atgcagaaaa tattcaattg gcccggtgac ttttattata ttcgtagact tcactggaca
     8941 gtccaaggtg atatctataa tcatcaatat caaatccatc atttcaatca gcaaatcatg
     9001 aaaatggata aagcaacact tttttcagga gattactatg tattggatgt ctcaaatgat
     9061 gaagatgctc cagtttgtat ttgtattgct gcggttttag attactggct ctaccgtaaa
     9121 gacaaaagtc gcgataagcc tgtttcttac cgacttaact taagttaaaa agatgtacct
     9181 gaaatgcgga aatacgcatt tcaggtacat ctttttagat attcttttgc atatgatcat
     9241 aaagatgacc actgatcatc cgctgaccga caactttgaa gtcatggcgt tcgtataatt
     9301 ttttagcctt tggatttttt tcatccacac ttagaccgat gacggagcga ttagctttct
     9361 tcgccaattt aggtaatgct tctaataatc gcgaaccgat gccttgtcct ctaaaatctt
     9421 ctgatacact gatagagtcc aaataccatt cgttgggaaa cgtttcttta tcaatgaaca
     9481 aacgtgtaga cgcatctagc tgatatttct ctaagatagg taccagtggc tgatcgatga
     9541 ttgattcttc ttcatctgta taaccgtaag caactcctgc aactttaccg tctatttctt
     9601 ctacgatacc tcgtgaataa ctgtaacgat aatttggatc agtgattgct tcttctaaaa
     9661 tctctaaagt cttttgttcc cctgtctgct tcaaaaatgg cagttccata tcttttagaa
     9721 tcactaagat caatggggcg atttctggag catcttcttt tctcgcaaaa cgaatcatag
     9781 tttcctctcc ttttctccat tctaacatgc agaaaaagaa atcgcaaaat cgttatttta
     9841 aaaaatcttc aatcttttca gtaatgaaat aaccatgagt aacgattctt gccgcttcag
     9901 ttcggcaata agggcagacg actggcattt ctttatcatt atgttcgact acattattga
     9961 cttcttcgta tgcaaatttt tttccgcaat tagggcattt cattttttcc atgttatctc
    10021 aacttccttt catctttact ctcttagctt actcttatat tgtaaaaaag agaagcaata
    10081 tccttcttct atgcagatat ccatacctga cggtcctgtt ctccatctat taatcggact
    10141 ttataataag gacgttcatc tttgactaga agtgtccact ctttcacttt tgcttttttc
    10201 ccgtagtagc tgactgcttc cttcatcgct gcttgcggtt gtttgaactc ttccgttttt
    10261 tctatatcaa aaagatgttc tgcggccttt tccgtgtcat ttcgtacggt tgttttccca
    10321 gtggatggat tgactgctat gacttgtcct tcacaaaaaa actggtattc atatgttgca
    10381 ttcgtaggat tctccaaatc tttttcaact gcaaaatgaa tagcagatat gttatgttct
    10441 tttgtttcgt tttttacgat tgctgctgct tttttcaatg agatccgata ttcctggtca
    10501 ctaatatcat ccatgtgaaa agcggcattg agcagtcccg tcataccggt aatccctatt
    10561 acgatgaggg cagcaacacc aaacatcatt tttttcattc ttcattctcc tgtttctttt
    10621 ttttaaagaa tatcaagaaa tgaacgaatg aaaaatcgaa tgaaacgaaa aaaaagtgac
    10681 aattttgtta tctttattcg tgcagttcta atggcaatcc gtctggatca aagaaaaacg
    10741 tcattttttt tcctgtaaag gtatcttctc taatcggttc tgattcgatc cctaaggact
    10801 gcaattctgc aattgtttct tcaatatcgt ctactttgaa agcaagatga cgcaagccac
    10861 aagcttctgg atagtttggt cgttgtggcg cattagcaat tccaaaaatc tccaattcag
    10921 cacttcctag tttcagatct aatttatagt catctcgttc tttgcggtaa ttttctctga
    10981 ttacttcaaa tcctaattta ttaacataaa aatcacgtga tttctgataa tctgaaacaa
    11041 tgatggctat atgatggatc gttgtaaggt tcatatgagc actcctattc ttcgtttaag
    11101 ctcggatcta tattaatctc cagttccatt gtaaatgtgt cagattgaaa aaaatagctg
    11161 tttttccttt ttataagaaa aaaggcaaaa aaaacagaaa gtaggtcctc caagacactc
    11221 ttcctgttcc caatataata aatgaaagta agaaattata ttttcaagaa aacaaacaga
    11281 aaattatcat aacacaaatt atttataatt gaaagactag ttttttttca agaaaagcat
    11341 acaatagatt gtgttagtaa atacagaaca cactacattt agtgtcttaa ggagtcctca
    11401 tacatgaagt catattttca gtttttagct catcagctaa aaggctggcc gcaacaaaat
    11461 tattatcttt tctttttcag tcttggctgc caggtcatga ctcttgtcaa tagtcccatc
    11521 acttggctgt ccgttattac atttatcggt accacgcttg gtgtattgtg tattttatcc
    11581 atcaatgcgg caaaatcagt caacggtatt ttaggtattt tgtctgcgat ttgttttatt
    11641 atcgttgggt tttcagcaaa gaactattta agtatcggtg aacagattgc ttatatgatc
    11701 acattggata tccccgtatt gttaagtaaa gaatggaatc ataatatggc ttcaaaaatc
    11761 cgaaaattca ctggaaaaag ctggtttatc gcaatcatca gtactttcct tgtctatctt
    11821 gtttcaggat tcctgattgg tcgttataca gatgatcctc ggccgtgggt agatgccatt
    11881 gctttttcta ttagcttgac tgctggtatc atcagtttct tgcgttacaa caaccaatat
    11941 tactggtggt tagcttcagg gcttgctcaa atggtccttt ggtatatttc atttacgcat
    12001 ggatctgcaa gtttggcgat gttcgtgaac agctctgttt acttgctgaa tgatgtcctt
    12061 gcatttaccg tttcaccttg gtataaccaa aaagaacgtg aacgtatgca aaaaatggaa
    12121 gaagaatact acaacgcaca acaacacgca taaaaaaact gagcgtggga caaaagtaaa
    12181 gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaatcagaag caactccttc
    12241 ggaaataagc tgaaattcac aaaaatttga aaagcaattt tcgtgaattt cttcttattt
    12301 cttggagtta aacgcttctg tcccagcctc tatttcctac gattagtcaa gtaaaaggtg
    12361 caagaaaaat agctcgtaaa cgaaagcgac aaaatcaaag cacaccaaat aaagccccgt
    12421 tcgtaaaaaa ttttcgatct gggcaaagaa gtggtatact gtaagtggtt tagttaatgg
    12481 tccactgaga ccgcgtacgc atagtcgtac tctgtatgtg ccctaaccat agcgtgcata
    12541 catttcagaa gcttgttcat acaagcaact gtggcaacct tatctttctt agggataggt
    12601 tgctttttta atttgtagta ataatcgaca atatgattag gagctgcgcg ttgctggcga
    12661 atcatatttc gaatggtgaa gaaaataatt ttccgtgctt tgggattacc acgcttattg
    12721 atgcggtctt ggccagtata cttacctgaa tgataccgtc ggatgtcgat tccgacaaag
    12781 gcattcaatt gtttatgggt tttaaatcgt gtgatatctc ctaattcacc gagcaataaa
    12841 gcggctgtga gtgcgccaat cccagggaac gtttggtaca acaaaaagca aggagagcct
    12901 tcggcttttt tgatcatttg tgtcgccagt gctttttttt gttcgagtaa atcttggaga
    12961 agttcggcgt aatagatcgt tttttgacag tggatactgt ctttttcaac agctggatag
    13021 gcacactgtg catagtggat gatttgatct gccttttgct cggcacgatt cgcggagatt
    13081 tttttccgtg tttcgttgat cagtttattt tttatttttg tccgagtaga tgccaataca
    13141 aaatctggat ggggaaaaag acggatcaat gtcaatgcgt aaggggtcag cctgtttgaa
    13201 aagaactgtt caagctctgg aaaagtcaat tgaaggcagt tgtgtaaatc catgcgcaga
    13261 cgagtgattt tcttctcaat ttcttgataa aaacgggcta aatcgcgcat ctctaagtaa
    13321 aaattgcttt gtacttcttt tggctgacgt tgatttttaa gatgagtctg tgcgagccgg
    13381 tgggcatccg atttatctgt tttccaactg cgtaaggtgc tttcttccat ctgttttttc
    13441 gcctctaacg ggtttaacaa acagtaagaa aagtgatgat cttgaaagaa cttttcgact
    13501 ggtctggaat aaatccccgt tgcttcaaaa acaatcaatg gacgctcagg caagtgctgg
    13561 atctcttcga gtaatgcatg aaatcctctt tgagtgtgtt caatctcgtc ttcaaataag
    13621 caggtgtcgt ctttgtatag gacactgtag ctgtgtccca ttgaaacatc taatgcaaga
    13681 atgtaaggca tttgttttcc tcctttttaa gttttgaaag aactttactg cttcatttcg
    13741 attccaattt cctatacacg ggctcatggc cccaacatac gtaaacctga ttctaaaatg
    13801 acagtaaaga agttcggttt ttgataggga ctcgtagtcc tcaaggcttt gttcgaactt
    13861 tctttcactc ttcactataa tctaaaaata gaaaatagag gagaacatca ttcgtcaatg
    13921 atgttcccct ctaatcttag tatgtttttt atagtaattc cttcagatac tttcttgcct
    13981 catcattgaa acgcagtgat tcttctaact tctgataata ttccaacgct tgtttctgag
    14041 cttcagtaaa acgataatgt tttcctttcc atttgtcgat tgtctcttgc acatttccag
    14101 attggatatc tttcactact agttgccatt tttcttttga gactgtacgg tctttcttat
    14161 cagcagattg tatagcttct cgttctttac gcaatacttt taaaaaacca tttctgacta
    14221 tccgaggaat gctgtcgaag aacccttctg taaaaccata gcgacaatat tgcttccaaa
    14281 taaatagata gatttttggt tggatgaatc gttggttttt cgcaaaatat tccatctgag
    14341 cagtgacttc tggtgttcgt tgacgttttg tctttctcaa cacggaaata aatgtttcaa
    14401 aataagcatt aggatgtact ggcacttctt catatacgat ggattgccaa tctttacgta
    14461 aaaatgcgcg atagttgatc aagaattctt ctacatcctt tactaattct tctgcaaagt
    14521 cgtcaaatag ttcttttttt atctgtcgct tttttgactg cccattgatg tgttcactta
    14581 ttttcttgat ttcattttcc aatgcttgat aatccgctat gtaaatcggc atttctactt
    14641 ggcgaaattc tgcgagccgc tgagctaatt ttatatccgg taaatatggc tgtttcatcc
    14701 gacgattttg gtacaagaca aaacagtatt tttgccatag tccttcagga aaatcgatat
    14761 tcttctgctt aagccataat aattcgtcta aggccagatc aacttttgtc attccctgat
    14821 ggatcgaagc tgccactgtc ggagagacat gcaggtgatc ggcaaagtgg ttgatgccta
    14881 gttttaggat ctttccggtt tttggcgatt taacgatgta ttgcactttt aattctctac
    14941 cacactcaca atacaatttt tgctggcttc gttttgttcg aaaaaacgga ttgatcttga
    15001 agtcagaaaa cacccaatct gttgcagcta aataatgttc ttccataaaa cgagagctga
    15061 ttagatatcg gcggtgctta tcgactagtt cccgctgttt tttcgttaat tttgcataga
    15121 tctcccaacg ttgactgctt gtgtattgtt tagaaatttt gatgggatag cttttgctga
    15181 tttcttttgg aaaccattct tcaaagacgg attgccattc ttccacggct gtttctttcc
    15241 tttctaatta caaaaagctg gctactaaca taacgttagc aaccagccag tgtttcttgc
    15301 taaattagtg agttgttccg gcatttccgg aaatatcttc tttattttct actgctgctt
    15361 caactgcata agtcaaagaa gaagcaatgt cttctaaaga catagaaggc gtacccactg
    15421 gacgatcgat cacttgatcg ggtgagaatg gcacgtggat gaacccacct cgaattgccg
    15481 ggaattgtgt ttcgatcaaa tgaagcaaac gatacatgat atcattgcag acaaatgttc
    15541 ctgctgtata agagatgtac gctggtagac catgatcttg tacatttttt gtcattgctt
    15601 tgattggcaa tgaggtaaag taagcggctg gaccgttttc ttctaaagcc gtatcgaatg
    15661 gctgatttcc ttcattatca gggattcttg cttctgctag attgattgcg acacgttcga
    15721 acgagactgc tgaccgccca cctgcttgtc cgacacagat cacgacatct ggttggtgct
    15781 gttggatggc ttctttgact acttgactgc ttttttcgaa tacggtcggt acttccactt
    15841 tgatgatttc agcaccgctg atttcatctg gcattttttt tactgcttca taggctggat
    15901 tcactttgtc cccaccaaat ggatcaaaac ctgttactag tactttcatc tgttgttcct
    15961 ccgtccgatt gatttaacat atggttatct tttatcatac cattttcctt gaacagcgta
    16021 aataaaggaa acaatagttt aaataacata acagatcaaa cttaatatat tcttataaaa
    16081 aaatagtgtt ccactacaat gttagaagag gttgcgacaa ttattctgtc acaacccctc
    16141 tcttctatta tttaaataga atcatataag caatttggaa aactagcata aataacgcaa
    16201 taaacaactg gtttttgatc actccgtatt tgtctttcat ctccagcatc gctacaggca
    16261 cgatattgaa gttagcagcc atcggtgtca gcagggtccc acaaaaaccg caagtcaatg
    16321 caaccattcc tattaacgct ggattcgctc catgactaaa tacgaatggt gcaccgatcc
    16381 caaccgtcat cacggtgatg gccgcaaatg cattccccat gattaccgta aatatcacca
    16441 tgccaagagc gtaaatgatg atgccgatgt tcacatttcc ttctggaacg atcgtaccta
    16501 ctgcattgga aatcactgtc ccaactccag cgcttgtaaa taccgcacct agagaagcta
    16561 aaagcattgg caacatgctt aacggcccta ctgtgcccag catatctgct gcatcatcta
    16621 aaaatgtact tggtcgatta tctcgagaaa agaacatcaa gattagcatg gctgcaaaaa
    16681 caccgacgcc cacgccgact aaagcaccta aattggtaaa tagagcaaac aagatcgcaa
    16741 agacaccgat actcaaagct ggaataaaaa ttttcattcc tagtttgtct gacatttttt
    16801 ccatatattc ttttgatgga agccggcttt ctcctttgct gactttctta gcaattgctg
    16861 gtatggtcat cgcaaagatc aagccaccgt tcacgattgc cggaagccat cttcctcctg
    16921 caataactac ccctaagacc gtccagaaaa aggctgaccc ataacgatga ggattggttt
    16981 tatctgttaa atttcttact ccagtgtaaa tcaatacgag tcccatcacg atataaagga
    17041 tctccagtaa tttatcgcct aataaaatat caggatttgt aaaaaagtcc atcttattgc
    17101 ccctttcctg gataatattt cttcgctaat ttcttttctt taagatagaa gtagacactt
    17161 gccacaacta aagccgtgat agccactgga acttccacta aagcaagctg tcccaatgtt
    17221 acgtcatatc ctagatcttt cagtgttgat tggactagca acgcccctgc tcctccgatg
    17281 aatagtactt ggccaaagaa ccagcagaca ttttccatag ctgaagccat accttttagt
    17341 tcttcttcat gcttaggatg gacttctaac ccttttgatt cgatggtccc caatgccatc
    17401 ggtaaaatga ttggacgaac aaatccagca actccaccaa aactcacgtt aaaagccgca
    17461 aagatcattc gaaagatccc ataaatatct acaatcatac cagcagatac tttcttgaat
    17521 cgcttgatca aggaagccgc tgattctttc agaccatttc tttcaagcgt tcctgttgcc
    17581 aacataatga tgataaaaat cgccatcccg cgattgttta caaaacttgt acctaaaagt
    17641 tctaacattc cttgaatgcc aagaccgcca gtcaaagctg taacaactaa agcaaccatt
    17701 acgatcaata tcgagtctaa tttaaatgca aacccgagaa taacaatcaa gacgcctaaa
    17761 aggctaagat aattttccat atattttcct ccataaaatg acaatatttt tttaattata
    17821 aagcaaaaca cataaaaaat atagttgttt tctcacgaaa tagacactat ttttaaatat
    17881 ttttcgttat ttttttatca caaaaattat cttacttatt gtaaggtaaa
//
LOCUS       DAZKCH010000057        17538 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000057 DAZKCH010000000
VERSION     DAZKCH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.057"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            283..522
                     /locus_tag="ACG84X_001965"
     CDS             283..522
                     /locus_tag="ACG84X_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127812.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="ACG84X_001966"
     CDS             complement(884..1144)
                     /locus_tag="ACG84X_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127813.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="ACG84X_001967"
     CDS             complement(1329..1826)
                     /locus_tag="ACG84X_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFP9127814.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="ACG84X_001968"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="ACG84X_001968"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFP9127815.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="ACG84X_001969"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="ACG84X_001969"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFP9127816.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5210)
                     /locus_tag="ACG84X_001970"
     CDS             complement(4548..5210)
                     /locus_tag="ACG84X_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFP9127817.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5220..6035)
                     /locus_tag="ACG84X_001971"
     CDS             complement(5220..6035)
                     /locus_tag="ACG84X_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9127818.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6297..6740)
                     /locus_tag="ACG84X_001972"
     CDS             complement(6297..6740)
                     /locus_tag="ACG84X_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HFP9127819.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6874..7212)
                     /locus_tag="ACG84X_001973"
     CDS             complement(6874..7212)
                     /locus_tag="ACG84X_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9127820.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7200..7577)
                     /locus_tag="ACG84X_001974"
     CDS             complement(7200..7577)
                     /locus_tag="ACG84X_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFP9127821.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7801..8994
                     /locus_tag="ACG84X_001975"
     CDS             7801..8994
                     /locus_tag="ACG84X_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9127822.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9160..9582)
                     /locus_tag="ACG84X_001976"
     CDS             complement(9160..9582)
                     /locus_tag="ACG84X_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9127823.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            9977..10171
                     /locus_tag="ACG84X_001977"
     CDS             9977..10171
                     /locus_tag="ACG84X_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127824.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            10168..10662
                     /locus_tag="ACG84X_001978"
     CDS             10168..10662
                     /locus_tag="ACG84X_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127825.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(10824..11996)
                     /locus_tag="ACG84X_001979"
     CDS             complement(10824..11996)
                     /locus_tag="ACG84X_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9127826.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12202..13017)
                     /locus_tag="ACG84X_001980"
     CDS             complement(12202..13017)
                     /locus_tag="ACG84X_001980"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFP9127827.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(13167..13613)
                     /locus_tag="ACG84X_001981"
     CDS             complement(13167..13613)
                     /locus_tag="ACG84X_001981"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFP9127828.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(13610..14125)
                     /locus_tag="ACG84X_001982"
     CDS             complement(13610..14125)
                     /locus_tag="ACG84X_001982"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFP9127829.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            complement(14198..15112)
                     /locus_tag="ACG84X_001983"
                     /pseudo
     CDS             complement(14198..15112)
                     /locus_tag="ACG84X_001983"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            complement(15109..17436)
                     /locus_tag="ACG84X_001984"
     CDS             complement(15109..17436)
                     /locus_tag="ACG84X_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HFP9127830.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5066 a         3482 c         3052 g         5938 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca acttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaacctgg accaataaaa
     5041 agtaaagaaa aaataaagga aaagacattc cttccatcta tcgacaaaag gaacgcagct
     5101 gctatataca agatattgac acaccaaaaa caaaggctac ttgccaatga ttgatacaac
     5161 caataaaaga attccatata aacatttttg tcaaaacgct gctctttcat aatcacctcc
     5221 tattccttca ttcctgatga agcgatccct tctacaaaat atttttgcat cgctaaaaat
     5281 ataaaagcaa caggaagaac agaaacaact gaggcagcca tgattaatgc gtactctgca
     5341 tcaaatagcc caataaacat tttcaaccct aactggattg ttttattttc cgtagaagac
     5401 aaataaatga atggccccat ataatcgttc catgtattaa cgaatgtgat gatcgtcaaa
     5461 ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc gatagattcc ccactctgat
     5521 aagccatcga tccgcgcact ctcacataaa gaatctggga tactactgta gtattgcttc
     5581 aacaagaaca caccaaaagc attgaacgct tgtaatagca ccaacgacca caacgtatat
     5641 gttaaaccca cttttctcat cataatgaac tgcgggatca tataagactg ccaagggaca
     5701 gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc ctttaaaatt tagtttagaa
     5761 aacccgtaag cagcaaaact agaagtaaac aactgaatca acgtgatcac aacgcttaaa
     5821 aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag accaaataac cagataattc
     5881 tctaaatgcc aagttttagg gatccattga atcggaatcg tgaacacttc attatttgct
     5941 ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg tcaataaagc taatacaatc
     6001 agcagaatca tacccaacca ttgaataaag ggcatgtttt ttgaacgaat ttttgctttt
     6061 tttctttcat ttcgaacacc tccaaagtta taatcttcat ttctttgtaa tgattacaat
     6121 ccagaacaac ggttattata gctgattcat ttccgttctt cttatgtttg taagcgctta
     6181 tttaacaagt tatgtaaatc tctttatttt ttttgattta aaaatgaaaa aatacaaaag
     6241 caagactgtc atacgtctcg cttttgtatt gaaatttctt cgattagaga tacttattac
     6301 tgttcaaaag cttctttgaa acggtgaatc aattcattga ctacaggtga taaaatccga
     6361 ttctttttcc agactagcat gcagttcgtt tcaatcattg ggtcaagcgg aacgaatgtc
     6421 actcgctttg aaagatgact tacagcacct tctatgacta aagcagcacc tacctgattc
     6481 tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc ctgtgatcag caactgctcc
     6541 ttttttatgc ctaaccagtc agcaaacatt cgctgtattt ctggacgctt tgagatcaaa
     6601 agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt tttttgctaa aacagaattt
     6661 tctaaaatga gcaatcccca tttttccttt cttggtaaca aaatcgtttc gtatttctct
     6721 gtatctactg gatctagcaa aatcgctaaa tctaacaggc ttttttctag tcactccgtg
     6781 atatcatcac ttgttccgct gtggatatga aattgaacgc tgggataatc acggatcaac
     6841 ttttctagta atagtgccaa tgtattcgaa ttatcagctt ccacacagcc gatcgtaaat
     6901 cggccgctga ataattgttt ttttctgttc tcgaattctt gagtggtttg attcgttaaa
     6961 tctaaaattt cttctgctcg gcttttttag aaaataacct gcttctgtca agatcatttt
     7021 gcggttttcg cgtacaaaca gttctgttcc tagttcctct tctaactcct tcagttgtcg
     7081 gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct tgagagattg ttccttcttc
     7141 tgcaattgtc caaaaatatt ttagtaagcg taactccata gcgatgctcc ttgatttttt
     7201 tacttgatac attccatttt atttctagat aacacacgat catatttctt gatttttcct
     7261 tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt tcgtcaaaag ttcactttct
     7321 tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc cttcgctaga taggcgaata
     7381 tattcaatca aagactcgat cgataatccg gcatttcgca tacagatcgt aaagtcgacc
     7441 cattttaggt cttcttctgt ataatcacgg attccgcctt ttgtccgatt aactggtgga
     7501 atcaacccga ttcgttcata atagcgcaat gtatcggccg aaatgccctt ttcttcactg
     7561 acttgtttga tattcatctg atcactcttt ctcttaattt cttgccactt tacttatgta
     7621 ttttatttat tctacaactt taagtgtact ccaagtcaat actcatttct attaaaacta
     7681 agctggatta tctatatcgg ttgtttgtgt attatttcaa ataaaaaagt cttgtttttt
     7741 tattcttttt tggatatact tttaacaatt tagggaaatt ttaggaaaag gggtataaaa
     7801 atgacaacgt atcagcgaaa ggtattatta tcgacatcgg cgggaattgc tttagagaat
     7861 atggatatta tgtttttagc tttttcatta tcttcaatga ttacttcttt tcatattagt
     7921 ggtacgcaag cgggtttcat ttcaacgatc actaatttgg ggatgctcat tggaggtatt
     7981 ttttttggca tcatagctga taaatatgga cgtgtgaaag tattttctca aacggtcctt
     8041 ctgttttcga ttgcttcttt attgatgtat tttgcttcaa acatctactt ggtttatctc
     8101 tttcgcttta tcgcaggtgt aggagcggga ggagaatacg gggcgtgtat gtccttgatt
     8161 tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt cggttgctgg tattggtgcg
     8221 caggtcggtg cggctttggc tgcgatttta gctgctgtga tcattccaac gtttggttgg
     8281 aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg tcttgttcat tcgtcgcggc
     8341 ttgactgaac caaaggaatt caaatctgta caatctgccg aaaagaaaac caaacttagc
     8401 agactgtttg aatcaaaaca tcttgcttgg caaacatgtg gccttagtat catggtaact
     8461 gtccaaattg ccggctattt tgggttaatg aattggctgc cttcaattat gcaaaatcga
     8521 ttagggcttt cggtttctgg gtcttcattg tggatggtca gtactatttt aggcatgtct
     8581 ttggggatga tgacttttgg cataatcatg gataaattgg ggcctaaact agccttttct
     8641 ttgtttttaa tttgttcatc cttatctgtc tatctacttg tgttagccca tagccagtgg
     8701 agtttggtag cagccgctgt gatagtcggc tactttatca atggcatgta tggtggatat
     8761 ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg cgacggcgaa taatttcatt
     8821 atgaaccttg gacgagctgt tggtggtttt tcttctatcg tcatcggttt cttgatggat
     8881 cattatagtt taactgccgt aatcttgttt ttgagcggta tttacctagt cagtctgctg
     8941 gtcttgacaa ctcttactgg tgttacagca ttaagggaaa gcttgcagca ttgatagttg
     9001 agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc atctgcggta ataagaccag
     9061 ccaaatcaaa aacatgagac actgtttccg tttggctggt cgtattactt gatgcagggc
     9121 agctttttca actgctaatt tccttctatc tggcggcgac tattctttga cgtccgtcat
     9181 ttcaaagtac tttactaata acttagcata acgaaaaact gtggatacac tcgtatattg
     9241 agcgtctgca taatcttcca aatttttctc aggatgttga tacatgaatt caatcaaatg
     9301 ataattatat gattttctgt agaaatgaag ataaataatg tagattggga agttctcctg
     9361 cttttccata gaaaagcgcc gattattctc attcttcaaa atgaccttat caggatattt
     9421 ttggaacaat tcttctaaat ctgttagata attcaagata gacttacttg ataccttcaa
     9481 ttcgttttgt agttcttcta ttgaacacca acgttctgtt tcaagcagta aatgaatcat
     9541 tttaattttc ttttgagaaa cttttgttaa aaaagtctgc atattttctc ctcctgtatc
     9601 tactttacta tactacatac aagaaaaaaa acggatacaa atatcatatt gtcacaccgt
     9661 caatagtgca taaacctgtt attatttctc tttttttcct aagtattcta ttgatatgaa
     9721 tcatttaatc gtttattata taaatgtcaa taatctaata ataaaataac gtacatattt
     9781 tattattgca tacttaataa cagaactata gcaaaaaatc ccgtgtatca acacgggatt
     9841 agattaagtt tcctcaatca ctattcataa cacaattatt ataacaagta agtaaacaat
     9901 tgaaaaggac atttattgaa aacggttgtt ttttacttaa ggaggaaatt tagcgaaaaa
     9961 attagttgca ttgtttttgg tcgcaggaag tttgttgagt gggtgtggtg ctactacgtc
    10021 tactactcaa agcacaagtt cagatcaggc ttccagcagc agtaccacga tctccgaaag
    10081 tacggcagat tcatcgaaag aacaagaaca aattgaaaag aaaaaagaag agaaacaaaa
    10141 agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg aatctgcttt gtcacaagct
    10201 gaagcaaatc ctacaaaaga aaactatgca actgcttcag cagctatcca agcgctacct
    10261 gaaaacaaac aagagttgac aagccgtctt gctgcaattg attccacaat caaagcaaaa
    10321 gaagcagaag aagaacggaa aaagcaagaa gaaattgcac gacaacaagc agaacaagcg
    10381 caacaagaag caatcgcaca gcaacaagca gaacaggcga ggcaagaagc aatcgcacag
    10441 caacaagcag aacaggcgcg acagcaatca gcagctgaac aggcctctca gcaggcacaa
    10501 gccgcagctc ctgagcaaaa taatgaacaa actgtctatg tcacaccgac cggttcaaaa
    10561 taccatacac ataaatgtgg aaatggtacg tatacccctg ccactttaag cgaagctcaa
    10621 gctcgtggtt taaccccttg ctccaaatgt tatggaaact aattcaaaag ttatactata
    10681 ataataaaat tcttctgaaa cataaaaaaa tagaagatgg cgttccagat agtaaaccaa
    10741 aaataacagt ttacacgtcc atttcgtcag cttctctctt ttttcattta gtctgttccc
    10801 tctgcttttt tggacatctt cattcattct ttctcaatca aatagtacac ctctttttct
    10861 tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa actgtttcga atgtttatgt
    10921 tttacatgga ttttaagcag gagctcctca tgttgcaagc gatagttcct gccttttaaa
    10981 tcagaaaatc tcactagtcc gtattcatca gaagctttca caaatggaac tttttctcta
    11041 gtaatatagt gtttgccgtt gagcgttttt acagaaaaga ccattccttc gattggtcgt
    11101 ccgtttgtgt tctttacata aaaagataaa ggatagtttc gcttagcgat ggccaaagaa
    11161 tctaaataag cgatgagtag ccaaactaag ccgattgatc caagtagtat accgataaac
    11221 caaataaaaa atttccattt tttccattga tcaattcctt ggatcgcttt ttttgcctct
    11281 tttgcttgat aaggaatacg atgccccgtc acaagcagtc gatgtgtatt gaccatataa
    11341 ggagtacagg taagcaaagt cacgagatct ctgccttttt ggatacccaa agaatctact
    11401 tcatcaggta agaccacttg gattttttct acttgatacg ccaatgtctt tccattgatc
    11461 tggatgaaaa actggtctcc ttttttcaac ttaggcaaat ctgtaaataa ttttgcttct
    11521 gggagtccac gatgcccaga aagaacggca tgggtgtttt tcccgccagt cggataagaa
    11581 ctttcttcca ataatgacgt tcctttttgc aaaaatattt ccgttgtctg atcgaatata
    11641 ggtaagctga cattgatttt tgggatttcg atgactccaa gcatatgttc cataaaaaag
    11701 gcattactag gtaaatcttt taatgctttt gcatcaactg cttggttgaa actgcctatc
    11761 cctggtgata cgttttgctc tgccaactgt tggtttttct ttgtcatttt ttcctgctgt
    11821 ttttttattt cctctgaatt cttattcgat gcttgctttt gataatggat gatcatttgc
    11881 tgggcaagaa aatcattcag tgaatcttct acaaaaggat aagaaaagat cccgatccca
    11941 acgactaaaa tgattgccat gaagatgtcc agtattctta ttctgctttt attcatcatg
    12001 tccacctatt ttctaatatg tatatgaaga ggttgtgaaa tcagcgcctt gacctgagta
    12061 ttagcgaagc aaacggcaaa atagttcctc ctattttgcc gtttgttgag cgaataccaa
    12121 gagaccgacc acttgtcaca acctttctcc ccatttgaat cactatcgtt tatttatcgt
    12181 atgatttttg tttccaatag tttaagcttc tgtttcttga tggcgttttt tgaaatagat
    12241 cactgctcct ccaactaaag cagtacctac caagatgaat acgatgatcc ccataccacc
    12301 agttgaaggc aagattcctt taggttggtt atcgatcgtt gtttcatcag aagttgttgg
    12361 atcatcatct actgtaaatt cagtgtacgc agcttcattc ttaggtaatg cgtagccttc
    12421 tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc agcccttcga ttgaaaattt
    12481 cccttctgaa tcagaaatca atttcacttc ttcccagtca gaacctgtga cttcatctga
    12541 ccaagcatat gggtattctc ctgaggcaag gtttgctatt tttttcatta atttaacagt
    12601 tggatctttt gctcttagaa tagaaaattc tgcatcggct aatttttctt gcgtgttcac
    12661 atcttgtttg atgaagtgga aatcaccgta gttttggaca ttttctacag taatcgtgtt
    12721 atccgtagtt gtattttccc gattgactac accgtttgga ttcccaagat tggcttcatc
    12781 tgcgccatgg atgataccgg ttgtttgttg caattttccg ttttttacta taaaagtagt
    12841 ttctttttgt ggattggtta attgataacc atctggtgct tttgtttcaa ctaaagtata
    12901 attgccgtct attaatccat tgacactgat ggatccttca gtatcagttg tgaatgtcaa
    12961 cgctgactca gcaggatcat agagagcgac accagtgttt tcatcaaaac cggtcacgaa
    13021 ttgattctct gaatttttga tctggaattg cgcccctgct aacttatcta cccctgaaaa
    13081 gttcccagct ttctggattt tgatattgct ttctttgatg acatttttag catataggtg
    13141 aatcgtgtct aaaggtttgt cagggtctag ggtaagctta acacgatatt tggcgacgtt
    13201 tcgacaccgg gctttggtgt ttctacaaag acgtatacag catctttccc atcagattta
    13261 cctggaagag tcaggttagc taatccttca ccagaagtcg ttacacttgc gaagggtgta
    13321 gcgtctgctg gaactgctgt gtctttactt ggatagtacg tagcagtgat gtcatatacg
    13381 ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg tcaattccgt tccgttgttt
    13441 atttgatttt ctggtgctga agtgaatttc aatttatgca aattaaccgt aacattttct
    13501 ggtgtaggtg atacggctgc agaaacctct gcagttccta ggccgagaac gaaaggaagc
    13561 agcatgatag cagttcctaa aaacgtccat atttttgttt tgatgttttt cattttattt
    13621 ccctcctatt gtttcctttt tgttgttttt tataaaacca agctgtccct gttgaaagga
    13681 ctagcaataa ccctaaaatt gagaaacctc caagcatctc ttcgcttgtt tttggaaagc
    13741 ttcctccatt tttttcattt gatggaccat ttgtctgcat ctgaactggc gtttttccat
    13801 tattcgtcgg atttgctttt ggttcgttga tgatttccaa tggtatagga tgaagcggat
    13861 cataactgcc tttttcaact tcaaagagaa tggttgattg actcaatata tatcctttag
    13921 gcggtttaat ctccactagt tcgtaacttc caaaagacaa tccatggaca gaaaatgttc
    13981 catctttact ggaagtaaaa atcgttgctc ttgaatcatc tttggctacc caatgattta
    14041 tcccgttttc ttgcgctaag tattggtcat tttttttgac tagaaattga gcatctgcta
    14101 gtttttgttt cgtttgccga tccactttga caaattgttt gcctcctgtt tggatggcaa
    14161 gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac atcgttatca aatgtcgttt
    14221 tttcactgtt ttctttcaat gtcatttggt aacggatcgt taattttttt ccagcaaacg
    14281 aactaagatc ttttccagaa tctgataaga caaaaccatg ttttattttt tgtgtgtgaa
    14341 atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt ttctggttct agccataact
    14401 gaggatcagc tgtatctttg atcgtatagg ttcctatctc gttgatgttc tcaggaattg
    14461 ttacggtgat gagataaggg actttatccc catctgcaaa atctgtctgc ttattctcta
    14521 ctgtttttgt taatgtgagt gcagcaggta ttttttgttc gctctttgga tacaagtgga
    14581 tggtcgtcaa tttatgatta gatgaatctg tcacaggaag cacaacgaca aatggtgctg
    14641 atttttcttt tacttaatct gaagtcttta tttccgtaaa tcggtaaaca gcgtcacgac
    14701 cttgctcatc tttgtccgat gcactaaaag aagcaatgcc ctcttcctcg tctactgttt
    14761 ttgtcacatt ttctgccagt attttttcac tatcactttt ttgtgctagt tttctttgtg
    14821 cgtcttccac actacttcct tctgaccgca gcttgtaaaa ttcatccgag acatcatata
    14881 tagcgaaagt aacgccgttc aaccctttta ctccttgaaa gttatccggg atatttattc
    14941 cgtcgttttg actgatactt ggcatcttat cgctttcgaa cattcgatta tgcaaagtaa
    15001 atgtaatagg tgattctcta gctgacacag tcggagaacc tataaaaaag accagtagga
    15061 taaaaaagag aacagcaaat atatccacac gtacattttt tgtttttttc atcgctgttc
    15121 acctgctttt ttcttacgat ggataaaata aaagaagcca gaaaaaataa agatcagtcc
    15181 taaaaagaca aagggcagta gacctatccc acctgtcgaa ggaagcaaga gagtcggatt
    15241 gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa ttattgttta cacttccttc
    15301 gcctaaacta atcgttacta tttgtgatcc aatatctgtc cggctgttaa ctgttagggt
    15361 ataatccaat gattcgccta agacaacacc ggtaacgtgg agatttccaa ccgaaatcga
    15421 gtgactttgg gcatcataat taaaggcagc gtcatcgaca gtaatcactg cgttagcttt
    15481 atagatggta taagttcctg atgtgttggc tatatcagta aatgacaact tgggatttgc
    15541 tgctttgact ttgtctattc cgctattcgt tagtttaatt gtatagctgc cagcattaac
    15601 catatttttt gctgattgtg catctgctgt gtaatccata ctgctaagtg ccacttgtac
    15661 tggagtaagc gaactagtga caccctctgc tagcttgaca tggattgacg ggacacctgc
    15721 ttttccatca tatgtcttac tgccactgag ctctaccgca ccgctgattt gcttaatcgt
    15781 atagacatca gatgtctgca cgatagtaaa taaatagttt gttctggcag ctagtttagc
    15841 tagtccgctt tttgtcaatt gccaagacgt ataggttcca atttcagtag gcgcagttac
    15901 ttcaactccc ttttcattca tcgctttgaa atcagttgga ttccatgtga tttgatcaat
    15961 actgagatca ttgtttaaaa gggatgttga ttctgtttta tcattaaagg catatttaac
    16021 gatcggtaca acagaaagac catcatagta cttactgcca tttgcattga ttgatactgt
    16081 tgcatttgtc ttataatata ggatgacttc agaaatctgt tttccatttg cgtcctttac
    16141 gattacattt ccatttgtat ctaaactagc taaaacactc attgctgatt ggttctttgt
    16201 ttctatcgct gaaacagctg taaaggtata tccgttgata gtaggcgtat tagtcgtcag
    16261 gtcttgtgca gcacttccgt aagtaagatt cattatttta gaaggagcaa tcatctgtcc
    16321 aaaatagtct tgatacttaa tagtgattgg tgtttgtttg cctgtatagg tcaccgtatc
    16381 gacgttactt tctagggctg tgaaagaacc gtttgtttgt gcaaaagaat agcccgttac
    16441 tgctgttgga gtgataacca ctttgtcacc cacatggatt ccagataatg tagtcccgta
    16501 cgttccgatt tttgctgctc caccattgac tgtataagaa aaagttcctg tccgattcgc
    16561 attgacctga accgttgctg cttgataggt tggaaaattt gaaacatttc ccttaccatc
    16621 aacgatctgc ccatttttga tcgagtaccc cgtgaatgga atatcatttg ctaactgtat
    16681 accgattgaa aaagtactca tacctcctcc ggcaggaagc cctccccatg ttgagggtgt
    16741 aaaagaataa cttttatccg cattgggtgt aactgaatcg atcgtatttc cagcggtagc
    16801 cacccccata tagatacttt ttgggaatgt gatagtagta ccatttactg tggagccaat
    16861 aaacagatta tggatatctg gacggttatc aataaaagcg attgctttgg ttacgccttg
    16921 taacgcagtt ttatccgcac tcatcgatcc gttaaccgca acaatgactc catctttggc
    16981 atatatcact gtatatccat ctggtatggt atgtccgttg aaattcgcag tggccgcaac
    17041 agtactaaat gtctggcttc tacctgtttc tgaataagct ttctcccctg ctgcttttgc
    17101 tgctgtgatt tctttttctg tcggatcaat cagttgagtc gaggatgtgg ttgaggttgt
    17161 ctcgttgttg ctagactgat tggtgctttc tatggactgt atttcagaat agggtggact
    17221 atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt tctgtataaa cgtttacata
    17281 aatacttgat aagctcccta agaaagtaaa aatcaagatg atcgaaatca taatgggatg
    17341 taagtatttt cttttagata cagctttgag tctagaaaca aaatgttttt gacatatacg
    17401 ttggatttta ttttgagttt tcttaatcat tttcatccct cctctcaata aaaaatcatc
    17461 aaataatcct ttacacgtta ttctaaattt aatttttatt attttattga tgtatagaaa
    17521 gtttggggct ttttttct
//
LOCUS       DAZKCH010000058        16582 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000058 DAZKCH010000000
VERSION     DAZKCH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.058"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(88..318)
                     /locus_tag="ACG84X_001985"
     CDS             complement(88..318)
                     /locus_tag="ACG84X_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127831.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(754..1320)
                     /locus_tag="ACG84X_001986"
     CDS             complement(754..1320)
                     /locus_tag="ACG84X_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9127832.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1320..2276)
                     /locus_tag="ACG84X_001987"
     CDS             complement(1320..2276)
                     /locus_tag="ACG84X_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFP9127833.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2276..2932)
                     /locus_tag="ACG84X_001988"
     CDS             complement(2276..2932)
                     /locus_tag="ACG84X_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFP9127834.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3302..5320
                     /locus_tag="ACG84X_001989"
     CDS             3302..5320
                     /locus_tag="ACG84X_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFP9127835.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5390..5596
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5747..8161
                     /gene="leuS"
                     /locus_tag="ACG84X_001990"
     CDS             5747..8161
                     /gene="leuS"
                     /locus_tag="ACG84X_001990"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFP9127836.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8509..10062
                     /locus_tag="ACG84X_001991"
     CDS             8509..10062
                     /locus_tag="ACG84X_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFP9127837.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10443..12227)
                     /locus_tag="ACG84X_001992"
     CDS             complement(10443..12227)
                     /locus_tag="ACG84X_001992"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127838.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12242..13963)
                     /locus_tag="ACG84X_001993"
     CDS             complement(12242..13963)
                     /locus_tag="ACG84X_001993"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127839.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            14063..14824
                     /locus_tag="ACG84X_001994"
     CDS             14063..14824
                     /locus_tag="ACG84X_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFP9127840.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            complement(15240..16412)
                     /locus_tag="ACG84X_001995"
     CDS             complement(15240..16412)
                     /locus_tag="ACG84X_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HFP9127841.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIGNSHNRL
                     KSTNLLERLNQEVRRREKIIRIFPNRTSANRLIGAVLMDLHDEWLSSTRKYIKFDQ"
     gene            16430..16549
                     /locus_tag="ACG84X_001996"
     CDS             16430..16549
                     /locus_tag="ACG84X_001996"
                     /inference="COORDINATES: protein motif:HMM:NF018061.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFP9127842.1"
                     /translation="MFLWLKTLYRKRAVTWPFIFYTIIWTLSKQTKNSDYADK"
BASE COUNT         5333 a         3076 c         3244 g         4929 t
ORIGIN      
        1 aatcccacac cttataaaaa tctttgacaa atctattcga aggatcaaat ttaaaccata
       61 attgcgtctc attaaaaagc ataaccatta ctccgatcta tttttaaact tagtctctac
      121 ctctaatata tatcgagttt ttattttgcc ttcagagaat actgtttctt tttttgcagt
      181 tacaggttgt ttattttcgg aaaaagctaa tatagctaaa attgaaacat ccatctggaa
      241 tttatctttt ttactgcttt gatcataaaa gtctgcatat tcatcactga tattttttct
      301 aataaattct tccatcataa aaatcacctc aaaacgatta tacgaactta cgttcttgtt
      361 gtaaagcgat atttgagggg caaaaaaggg gcataatttg actgatatta agttagctat
      421 tgatatatga atgacataca aaaatataaa atcttttaaa aatgcttata tatcaatgtt
      481 tttgccattc ttttatatat ctgttatatg tcaaaaaaat gtgttcaatt tcaatttgta
      541 tttgaataaa gaggttgtga aaaagctgtc ctgcatcaag taataagaac agccaatcaa
      601 aaacagcttc tcatgttttt gatttggttg gacttattac cgcagatata agcttttgag
      661 caccgtgaat aaagaggtta tgaaatcaac gctctaacct gagtattaga gaaaaaaacg
      721 caaaacatat catttatgtt ttgcgttttt tatttatctt tttttctcaa tacaatataa
      781 aataggcggc tggttctttt ggttgataaa ccgataattc agcacattat atgtttcctg
      841 tggcagtttg gaacaaaaag aatcaaccat atccagttct ttttctccac cttcatgacc
      901 atagtagacg acaaggatca atcgtccgcg aggcacaagt cgtttcaata tttcttccat
      961 agctgtgcgt gtagtctctg gcatagtgat gattgcttta tcactttttg ggagataccc
     1021 tagattgaaa atccctgctt tgagattttg ttgttcagct atcacttctc ctaacgtttc
     1081 gtggccttgt agaaacaatg agacacgttc ttctaactga cgctgttcta gcctttcacg
     1141 agtagcatcg attgcttgtt gctggatatc aaaactatag acatgaccag tttttccgat
     1201 gtgttctgct agaaaaaccg tatcgtggcc attgcccatc gttgcatcta cgacgtgatc
     1261 ccctggttgc aagatttctt gcagtaatgt atggctgaaa tgcaaagcag tttgcaacat
     1321 cagacgctca cctttttccg tacatcatat tttccttgga agctatctct gcgaagaagt
     1381 tcttcatcaa ttgcattcaa gacttcccat tttttcaagc tccacattgg tccaatcaag
     1441 gaatcccacg gcgcatcccc tgtcaaacga tggatgatga tctcttttgg tatcatttcc
     1501 agctggtcgc aaatgacatt gacatagtca ggacggctca ttaattgaag gcgaccttca
     1561 tgatagtccc gcaacattct cgttttgcgc atcagatgca tcaaatggag cttgattcct
     1621 tggatatctg aatctaaaat ggtgcgtctg acattttctt tcatcatttc taaactttcg
     1681 cctggtaatc cgttgatcaa atgcgtacaa acacggatat tatgtttgcg taatttagcc
     1741 acgccatcta aataagtttg ataatcatgt gctcggttga tcagttttga agtttcttca
     1801 aaagttgttt gcaatccaag ttctacccat aaatacatcc gctcgttcag ttcagcaagg
     1861 taatcaacta cttcatctgg cagacaatcc ggtcgtgtac cgactgataa tcctacgaca
     1921 cctggtaaat tgactacttg ctcaaatcgt tctttgatta tttcaactgg cgcatgggtg
     1981 tttgtaaaat tttggaaata aacgatgtat tgttggacat gaggccattt ttgatgcatc
     2041 atgtcgattt ctttctggaa ttggattgga agagggtctt caggtgcaac gatcatgtct
     2101 cccgaaccag atacactgca aaaagtacaa ccgccatggg caacagtccc atctcgattc
     2161 ggacagtcaa atcctccatc gatcggcacc ttgaaaattt tcccgccaaa ctcatttcgt
     2221 aaagcgtaat tccaagaatg atatctttta tttccttctg aataaggaaa agtcattaaa
     2281 agtccttctt tctgtaagag ttatctattt gttttctttt ttctctatac actggataag
     2341 tcaggcacag ccaagaaaga ctgagtaagt aaccgccgat gatatcagta ggaaaatgaa
     2401 cgcccagata aatgcggctt atcccgacac ttactataat aaacatcatc agcaattgaa
     2461 gcaatgtgcg taaggttctt ttttgaacaa aagctggaag cagaaatagt aaagaaccgt
     2521 aaagaatcat actgcctgct gcatgtccac tagggaaact gtaacttgtt tcaactacta
     2581 agtgcgccaa tgaaggacgc tctcgcatga aaaatagttt gatcaccggg ttgatgattc
     2641 cagcaattac aataaatcca gaaacgaacc aaaatgtttc tgcccttttt ttcttatacc
     2701 acatccataa agccgcacaa gcaaataaaa tgatgacggt aagaggatta ccgaatttag
     2761 tcataaagag ttggtagctg ttcagatcag gataagaagc tctgacaatg cctgtaaacc
     2821 actgatcgaa accagaaagc cacgacagat ggaactttac gatccagccc aaaatgaaaa
     2881 acaggacaag aaagaagcta ccagccacct gaaatgatgt tttatatttc atacaattcc
     2941 tcctttgaag caatgactta ttatagcatt tttggtccag cgaaaaaaac ggtaaagaga
     3001 taaaaccaat gtatgattcc tctttgaata accaatattc ttataaaaaa aataactgta
     3061 atcggaaaga cattttttgg taatgcaaat gaaatgttag ggaaataaaa tcagtgtttt
     3121 tcgaaatcct tttaaacaag aacgtagacg taggaagaac ttgaaaatga acagaagttg
     3181 ttcattacgg taaattacaa tatgattaca aaaaacaaca aagctcttaa ataactttta
     3241 ataaatatta agagaagtta taattattaa taatagataa attgaagttg gaggatagaa
     3301 gatggaaaac attgcaagaa aagaacggag acgtttagaa cagaccaaac gttttcgaaa
     3361 agcaaaacga ggggcagcaa tcgtgggaac tgcgatggta ggctgttctg tcgctgcccc
     3421 attagtacag ccggttcctg ttcaagcgga tgaaacacct gttcagttcg gcgcaagaat
     3481 caatacagcg gcatttatca cagaaattgc tacttatgct caaccaatcg ctcaagccaa
     3541 cgatctatat gcatcagtga tgatcgcaca agcagttgta gaaagcggtt ggggcagtag
     3601 tgcgttatct caagcacctt attataatct ttttgggata aaaggcagct atcaaggaca
     3661 aaccgtctac atggatacgc ttgaattttt aaataatcaa tgggtaaata aaaaggagcc
     3721 tttccgacaa tatccttctt ttgctgaatc tttcaatgac aatgcctatg tacttagaaa
     3781 tacttcattt ggcaacggtt attactatgc cggtacttgg aagagcaaca cgaaatccta
     3841 tacagatgcg acagcttgtt tgacagggcg ttatgcgact gatcctggtt acgcaggcaa
     3901 attaaataat atcatcgcaa cttacggatt gacccaatat gatacaccag ctagcggaaa
     3961 cgcaggcggt ggagcgacta caggtggcaa taatactgga agtgcaggta gtactggcgg
     4021 ttcaagcaat tctggtaata caaactcagg ttcagcaact tcgaccactt atactgtcca
     4081 atctggtgat tctgtttggg gaatctcaaa taaattcggt atcacaatgg atcaattgat
     4141 ccaatggaac aacatccaaa acaatttcat ttatccagga caaaaactga caatcaaagg
     4201 tagccaggaa aatggctctt cgacgaataa ttccggtaac aataccaatt cttcaggaaa
     4261 tgctggtaca tcaaacggag gacaaacaac tggtgcgaaa tacactgttc aatctggtga
     4321 ttctgtttgg aagatctcaa atgatcacgg aattacgatg gctcaattga ttgaatggaa
     4381 caatatcaag aacaatttcg tttatccagg acaacagcta atcgtatcaa atggcggttc
     4441 ttctaatgct ggagcaaata ctggctcaaa tactgggaat acaagtggct ctagttcgtc
     4501 cagctcaagt tcttctaata cagcttcagg aacgaaatat acagttaaag ccggagactc
     4561 tgtttggagc gtctcaaata aatacggaat tacgatggct cagctaatcc aatggaacaa
     4621 tatccaaaat aactttatct acccaggaca acaactgact gtttcaaaca gtggatcaac
     4681 aaacagcacg tcaggtaata caggttcgtc aaccaataca aataacagca gttcagttaa
     4741 tactggcagc agttcgtctc aaggcactta taccgtgaaa gcaggtgaat ctgtttggag
     4801 cgtggcaaat aaaaacggca tcacgatgga tcagttaatc gaatggaata atatcaaaaa
     4861 caacttcatt tatccaggac agcaattgat cgttaaaggt ggaacttcgg caaatacaaa
     4921 tacaggttca actacttctg cagcgaaacc aaatacaccg aatacgtctg ctacgacaag
     4981 tacatcatcc actggtaata cgatgtatac cgtgaaagcg ggcgagtcag tttggagcgt
     5041 agcgaacaaa catcatatca cgatggatca gttaatcgaa tggaataata tcaaaaataa
     5101 tttcatctat ccaggacagc aagtgattgt gaagaaaggt tcatctcaat caacaaacca
     5161 acaatcagtt actggttcga aaacctatac tgtgaaatct ggagaatctg tttggagtgt
     5221 tgctgacagt catggaatta caatggctca actaatcgaa tggaacaata ttaagaacaa
     5281 ctttatttat ccaggtcaaa cgttgattgt agctaaataa aatagctgtt cgaagaaata
     5341 acgattgaat tccacaaaaa tatttgttac tataaggcta cttaaatatg acaacacttg
     5401 aaaaggaagt agtaaaaaga ctgaagtttc agagagcgca tggctggtga gaatgtgcac
     5461 ggatgctttt gaactcgcct ttgagttgcc cttgctgaat acccgagtaa gcaagcggcg
     5521 gtgacggccg ttacaacgtt cgaggccttt tcactaaggt aaaattaggt ggtaccgcgt
     5581 agattacgtc ctataaaaag agcaatcttt ttataggatt tttttatttc ttttgtgaag
     5641 tttgagaaaa caaagcaaaa ggaaataaaa ataaacagat tctgccggtt ttttcgttat
     5701 atttataata gaaacaagtg ttttcaatag aacaggagga cagcaaatga gttacaatca
     5761 taaagaaatt gagaaaaaat ggcaaaaata ctgggcaaaa acgaatactt tcaacaccca
     5821 tgatgatcct gaaaagccaa aattttacgc actggatatg tttccctatc catccggtca
     5881 agggctacat gtagggcatc ctgaaggtta tacggcaacg gatatccttt cacgtgtgaa
     5941 aagaagtcaa ggatacaacg tgctgcatcc aatggggtgg gatgcattcg gtctgcctgc
     6001 tgaacaatat gcgctagata caggaaacga tccagctgag tttacccaaa aaaatatcga
     6061 aacattccga cgccaaatca attctttagg atttagttat gactggaatc gcgaagtgaa
     6121 tacaactgat ccggagtatt ataaatggac acaatggatc tttacgaagc tttatgaaaa
     6181 aggtctagct tatgaagcag aagtagcggt aaactgggta cctgaattag gaacagttat
     6241 ttcaaatgaa gaagtgatcg atgggaaaag tgaacgtggt ggctatgatg tagtcagaaa
     6301 accaatgcgc caatggatgc tgaaaatcac tgcttatgct gatcgcttat tggatgatct
     6361 agaattagtt gattggccag aaagcattaa agaaatgcaa agaaattgga tcggtcgttc
     6421 agtaggagca aatattgaat ttaaagtggc tggtacggat aaatcctata ccgtatttac
     6481 gacacgacca gatactctat tcggtgcaac ttactcggtt cttgcacctg aactagatct
     6541 tgttagagaa attacgaccc ctgaacaaaa agctgctgta gaagcttata tcgaagagac
     6601 agctaaaaaa tcagatctaa agagaacgga tcttgcaaaa gaaaaaacag gagtatttac
     6661 tggtgcttat gcaatcaatc cagttaatgg caaggaaatc ccaatctgga tcgccgatta
     6721 tgtattatct tcatacggca caggagccat catggctgtt ccagcacatg atgaacgtga
     6781 ctttgaattc gctcaaactt tcggactaga aattcttcca gttatcgaag gtggagatgt
     6841 tgaaaaagct gcttacacag aagatggtac gcacatcaac tctgaatttc tagacggcat
     6901 gaacaaacaa gaagcaatcg ataaaatgaa tgaatggcta gaagaaaatg gcgtagggaa
     6961 aaaagaagtc agctatcgct tacgtgactg gctattctcc cgtcaacgtt actggggtga
     7021 accaatccca atcatccatt gggaggacgg aacagtcaca gctgtcccag aagaagagct
     7081 accattacgg ttgcctaaga caaaaaacat caagccaagc ggtactggag aatctccatt
     7141 agcaaatatc gaggagtggg tcaatgtcgt tgatcctgta acaggtaaaa aaggccgtcg
     7201 cgaaacgaat acaatgccac aatgggcagg aagctcatgg tattacctgc gttatatcga
     7261 ccctcataac aaaaaagaac tagcagatta tgaaaagttg aagcgttggc taccagttga
     7321 catctacatt ggtggagcag aacatgcggt acttcattta ctatatgcac gattctggca
     7381 taaattctta tacgatatcg gtgttgttcc tacaaaagaa ccattccaaa aactatacaa
     7441 tcaaggaatg atcttaggcg aaaacaacga aaaaatgtca aaatctcgtg gtaatgtagt
     7501 caatcctgat gatgtggtcg aaacttacgg tgcagataca ctgcgcatgt acgaaatgtt
     7561 catggggcca ttagatgctt cgattgcttg gagcgaaaat ggcttagaag gaagccgtaa
     7621 attcttggat cgtgtatggc gtttgatcgt tgatgagaac aataaaatgc gtgaccgtat
     7681 cactacattg aatgatggca agcttgataa agtgtatcat caaacagtga aaaaagtgac
     7741 agaagactat gaaaatcttc atttcaatac agcaatctcc caattgatgg tctttatcaa
     7801 tgaagcctat aaagtggacg ctctgcctta tgaatatatc gaaggatttg ttcaactact
     7861 cgcaccgatt gctcctcaca tgggtgaaga actatgggca atccttggaa atgatggtgg
     7921 tatttcttac gcaccatggc caacatacga tgaagcagca cttgttgaag acgaagtaga
     7981 agttgttttc caagtaaacg gtaaagttcg tgcgaaaagc aatgttcccc gagacttagg
     8041 aaaagatgag ctagaaaaag cagcattagc caatgaaata gtgcaagaat atattgaagg
     8101 caaaacagtc agaaaagtta ttgcggtacc aaacaagtta gtcaatatcg ttgctaatta
     8161 attggctctt tgtcaataag gactgatgag ttgtgcaaaa tcaaatctgg gccagaatga
     8221 acttcattct gtctcagatt ttttgttatt tcaaattgat taattgattg atcaaaaagg
     8281 ttttgatttt catgttctca aacacgttca atgtcttttt cttctgaatg gtcttgtaag
     8341 agatctctgt aatcatcaaa tttttgtcta ttaatcttag tattttttga tgtataaact
     8401 acctgaaatt gagagtacat accaaattca taaatttttt attagtggga ctagtgattg
     8461 tatggatttt gacgcataat gaatgaagta tgagaaaagg agagacaaat ggatcaagaa
     8521 ctatttatta tcgaagtatt atcagctaaa caaaaaatta tcgagaaagc gaaaaaaaga
     8581 gcgaaaagaa taatgttcaa gcttttaagc ttagtatttt tctctggttt gctttttttc
     8641 ggagctgtat cgttcctata tcgccatatg agtgcagtag tccgttcagc tgaagggatg
     8701 caaaaattaa ataatttgta tcacttttcg tggggagttg gcggaataac aattgttgtg
     8761 cttattgttt ttcttctact tatttggctc cgttaccatc aattgtcgcg tcatttcgat
     8821 caatggctta gtcaaagagc acaacagttt ttacataata aaccaacttc tcaagatgat
     8881 gactatcttt attttgagaa gacttcgacg agtcaagctt ttcggataca aaaaagtgat
     8941 tgccagttat tgctgagatc acttgatgat ttacctatct acttaggcga aagcaaatca
     9001 aaattcggaa tgaacacatt ccatattttt ttactagaaa acgaacccag atgggaaaaa
     9061 agccagtctt cgcctggtgg atacctgaca actaagatga gtacattagt cactggtttt
     9121 ttcctcattc ttttagctgg aacaatctat tatgggagat acactcagcc aaaaatgtct
     9181 tctcatataa atgctgcttc tcacatgaca atgaactcaa ctaacgatac gcatatacaa
     9241 aagacaaatg aagggttgtt agctgatcct aagcaaaagg taaatttgac aacacaaaag
     9301 ataaatgatc tcaaacttga tacagagacg cactctctct atatgacaac agatagtggt
     9361 gctaattggg tatttgtgcc gattgattcg caatggttgc gttttggcga atacaccctg
     9421 acaacggggc tgattcctga aggttattgg atggacaaca catatgatat ttccgccgat
     9481 ttctcatggt ttatctattc ttctggggat gatgtacgtc tgctgacttc aagagataat
     9541 ggtaaaacat ggcaaacgtc tattatcacc caatcagttc agccgatacg ttatcgaaaa
     9601 gcggtatttt atggcaacga tggtctattt atctgtacat cagccagtgg gatgtctgca
     9661 gaaactttgt acatttacac tactatggat ggcggaatca cttggataaa aagtggaagt
     9721 acaatgatca atcagccagt acaaaatgtc agcttcgtta caacttcttt aggttttgtt
     9781 tcgacacgtg aaagtttgtt ttatacaaac aacggaggac gctcattcaa agaatcagtt
     9841 ctgtcgattc cggaaaacta tcagacaggg gggatagatc tttttcaatc accaaatgaa
     9901 gttactcaaa taagcgcgaa tacgttagag acaaaatttt atttgttgaa aaaaggacca
     9961 atcgatgcag ggaaaatgtt tgcctgcctc ttccgttcaa ctgataacgg ggaaacatgg
    10021 caattcgttc agcaactatc gcaagtagaa caaggagatt aaagaagaga gattgtgagc
    10081 ctgacgttca gcaccgagtc acaagaaaca aattcaaaaa acagcttctc atatttgttg
    10141 aatagtgtaa ctcgtgattc ggagttgaca agagcaacaa gaagcgattt tgaagtatag
    10201 cttctcgtat tttacaagat cgtgtcttat tgccgatagg ttgtctcttg aacaccgttt
    10261 attcgtaaaa agggattgtg acaagtcttt tgtcactact taccgaacga aactgaagga
    10321 gctatccaaa aagtatcatt agtattattc tttgtgtttc tagtggcacc actagtacat
    10381 ttaaaaaagc tatcgatcat ggactaatca tacatgatcg atagcttttt agataatgtt
    10441 tgttacgcta tctgaaattg actattataa agactggcat aaagcgttgg tgattggagt
    10501 agttcagaat gtgttccttt ttcgacgata tcgccattct tcattacaag gatcatgtct
    10561 gcattttcaa tcgttgacaa acggtgtgca atcacaaaac ttgtcctatc ttttgtcaca
    10621 gcttccattg cttgctgaat caatgcttct gttcgtgtat ctacgctaga agttgcttca
    10681 tctaaaataa cgacaggagg attcgctaga atgactcgag caattgtcaa taattgttgc
    10741 tgtccttgag ataacgtgcc gttttcgcta gaaatgatcg tatcatatcc gtctggcagt
    10801 gttcgaataa agtgatcaca ttgtgcgatt tcagccgctt cgataatttg ttctcttgtg
    10861 gcatccattt tcccgtaggc gatattatca gctaccgttc cttcaaacag ccaggtattt
    10921 tgtaaaacca tcccaaaaga acgacgtagt tctccacgtg aaagcttggt aatatcaaga
    10981 ccgtcgaatt cgatctttcc tttattcagt tcataaaaac gcatcagcag attgactaaa
    11041 gtcgtttttc ctgcaccagt tggaccaacg atcgctaccg tttgttttgg ctttactgaa
    11101 aaatcgactt gattcatcaa tattttatct gatgtgtaac caaactgtac atttttgaaa
    11161 gctatttttc ctttcggttg ttctaaaagt cttgcatctg gaaggtctgg aatttcatct
    11221 gtttcatcta atatctcaaa tatcctatcg attgctgcca ttgcggattg gatcgagttg
    11281 atcacataag aagcggtaga aattggttca gaaatctgat tgatgtactg aagataagct
    11341 tgtaagaagc cgatcgtcac accacctgat agaacaagca tagcaccgaa taccgcactt
    11401 atgatgaagg cgagttgatt aatgaaacga atggccggat agatagcaca gttcataaat
    11461 tgagcacgtt taaaagcgtt gtattgcttt ttatttactt cgtgtatagc agcttctgca
    11521 tgagcttgct gattgaatgt tttgaccact agattaccag ctaagatttc ttccattcga
    11581 ttatttaaaa cacccagttc atactgattc tgttcagaaa tctgtttgtt tttgttcgca
    11641 atcttagttg taacaattga actgccaacg atcagcaata agacgagcaa agtaagcttg
    11701 ctttcgatat aaaacagcat cagaccagca gcagctattg ttacgacaga agtaaaaaat
    11761 tgattgatac ctgtcaataa cacttgagaa agttgattga gaccggtagt tgtccgacta
    11821 atgatgtcac ctacttgatg attgtcaaaa aacgacatcg gtaatgtttt gaattttttt
    11881 gtgatttctt ttcgcaccct caatgtgatc ttttcgctta acgctgccat tgtccgttcc
    11941 tgaataaatg aagtgatgct gcttaagact gaacagccga tcagcaataa gacagggaac
    12001 aacaatgctt gtttgatatc actgaaagaa agctgtccaa tacctgtttt tcttatttct
    12061 gataagagat catcgatccc gattcccatg atcaagggca tggctacgac taataggttc
    12121 ccgaataaac tgcatagaaa caatccgtaa aaatatttat gttcaggttt gatcattttc
    12181 caaaaacgta tcaaagcacg cgtgttcaac gtttttttct tttccatcgt atcccttctt
    12241 tctatattcc ttgtgatttt gcaaactcct gataagtttg gcaattagac agtagttctt
    12301 catgagtacc ttgtccaacg atttttcctt catctaaaac aatgatgtta tctgcttgtt
    12361 ggattgtact gaggcgttga gcaacaatca cgagagtttt ctccgacatg tgtttatgaa
    12421 gggctgctct taatgctgca tctgttttat agtctaaagc ggagaaacta tcatcgaata
    12481 catagatctc tgctggtttg atcaacgctc gagcaataca tatccgctgt ttctggcccc
    12541 ctgaataatt agaaccgcct tgagcaacaa agctgtccaa tccgtcagga agggtgtcca
    12601 ctagttcttc taattgagcg atcttgatcg ctttagacaa ctcttctgtt gaggcatatt
    12661 catttcccat ctgcaagttg cttaaaattg tcccgctgaa taagaaagcc ttctgaggga
    12721 cataactgat gtgggagcgg atctgttctt gagtcatttg agtaagagga ataccaccaa
    12781 gggttacttt tcctatcgta gggtcactaa gtctcaagag aagtttcgcc aaactacttt
    12841 ttccagatcc ggtcccgcca acgatcgctg ttgtttttcc tttaggtatt gtgaaatcaa
    12901 tatcttctag aactggatca gagatttcag tatatttaaa tgtgacatgt tcaaaagcag
    12961 ctgcatttgt ctgatcaaag gttggttcag ctactgtttt gatcgtctct tcctcaattt
    13021 cgatctctgc ttgcagtatt tcttctatcc gtcgtaatga ggcaaacgat ttagggataa
    13081 tgaccaatac catagctgcg atcatcaagt aagcaagtgt cagcatagag tattcgacta
    13141 cagcagtcac gacaccgatt tgtaatgctc cttctgctac aagatttccg ccaaaccaca
    13201 aaatagaagc ataaacgatt cccatgagca aaaaagcaat tggagtgacc caagcaaata
    13261 ttcggttcac tttgatcatt tgattagcat agtcagcaaa gctcttattc gttcgctttt
    13321 cttcatatga ttgattatca aaggcacgga tcatattaat cccagtaaag aattctctca
    13381 atgtgatggt gatccgatcc atttttggct ggatactcaa agataaaggt gcccctcgtt
    13441 tcatcagtcg ataaacaatc catacataaa aaacaacaga gatcaatgta acccatgtta
    13501 gtaatagaga ataacgaaac atcatgagaa tggtgaaaac gcaaataacc ggtgctggta
    13561 agatcatttg gcaaaataaa acaatcattt gctggacatt atcgacatca ttcgtcattc
    13621 ttgtcaaaag agatccagaa ctaaaacgac tgatatcctt cattgacagc tgttggaatt
    13681 tacggaaata tttctcccgc gtttggaatc caaacctagc ggaagccaat gctgaaaagt
    13741 aactagaggc aactgcagcg attgttccta gaaacgctac aagcagcatt tcaactccaa
    13801 ttttttttat aactgaggct tcgccacttg ctatacctgt gtcgatcagc tttgctacta
    13861 attttggtac acctaatgta ccggcgattt ctaaacagat catcacaaag gtaaggagag
    13921 cgagtccttt gtttttctgt aagaatgttt ttaagataga catattattc ctcctttttt
    13981 cctgatactt ttcgattcta taccttcaag taacttgaag gtcaatagaa aaaagaataa
    14041 actgaaaaag aggtgagaaa aaatgaaaaa aatgtatacg attggccaag tatcggaact
    14101 atttgatttg ccaaaatcaa cgatccgcta ttgggatgaa caaggattaa tccgttcaag
    14161 tagacaagaa gagaatgatt atcgattgtt tgatatcgat gatattttta tgctttatga
    14221 tatcgttttt tatagaaaat tagatatacc gatcaaacag atgaagaatt tatatggaaa
    14281 aacattgacg gagttatatg agacacttga tgaaacagaa agaagaatcc ataaagaact
    14341 ggtggtgatg aaacaaaaac aaaaagagat aagggagcaa aaaaaacagt tgaaattgat
    14401 gatcgataca aacgaggaag aatttcctgt agaagagatc ccttttgact gtatgatctc
    14461 aacggagttt gaagatattg tggaaatcaa aaaatttcta cctaactatt caagctttgg
    14521 gatgatgagt atgccagctt ccagttcaca gacgatgtat ggatttttta tcgaccctag
    14581 tgaagtacat ttatttactc aagacgtgat ttgggagaaa aaagatacgg ctgtttatcg
    14641 tcgattctta ttgaaatccg agatgaacca tgcggaacgt aataatattt tagaaatcag
    14701 agaaagaatg tatgaaaaag gatggaaaac aggagaagtg atcggccagt atctattgac
    14761 gaatacggat gaaaacaata tcagaactga atattatcat gcatggatag aaatgaaaaa
    14821 ataggaaata tgtgtttaag ataactcgaa aatgatggtt gttttagtta taaagaaaaa
    14881 ttttctggtt cgattacggg tttaatgtgg gggattatta gtcgtggata gatagaattt
    14941 tagtttttta gaggaaatat gtctttaaaa atggaatggt tgcaattctt agcgatatat
    15001 acgatgtaat tgtcctctta aaaaagtatg gaaaaataat tgtattgggt gttatgtata
    15061 attcatggtg aactgagact aatgagaaga aaaattcata ttgttatgag tgagattgta
    15121 tcagatgaga atgataaatt aaataggtgc ataaaagcat tacacttaaa atacattgtt
    15181 gcttacatag tcaagtccat aatcctgtgt aaaatactat acaatgtttt accggtctct
    15241 cattgatcaa acttaatata ttttcttgta gaactgagcc attcgtcatg aaggtccata
    15301 aggacagctc caattaatcg attggcagac gttcggttgg gaaaaatccg aataatcttt
    15361 tctcttctgc ggacttcctg gttcagtcgt tcaagaaggt tggtgctttt tagccgatta
    15421 tgactatttc cgataaccgt gtattgaaag gcatcttcga agccattatc caatatttcg
    15481 caggcttttg tatatttagg ctggtcgata tattcaccga ctaaggcatt cttagctgtt
    15541 cgagcgagtt caatatccgt aaacttaaag atcgctttta ctgcttctct aaacggtttt
    15601 gaattctttt ttggaatgga actgaagatg tttcttaaaa aatggacctg gcatctctgc
    15661 caacttgcgt tggtaaatga cttacgaatc gcagacacta ggcctttatg ggcatcagaa
    15721 atgatgagtt ctgtcccctt taggccgcgt tcttttaagt attcaaagaa gatggaccat
    15781 gtgtcatcac tttcttcatt ttgaatcatg aagccaatga tttcacggtc gccaccttct
    15841 gttatcccga tcgcaatatg gcagctttta gaaagcactc gatggtcctc acggactttt
    15901 atgtagagaa catcagtcat cagataagga taattcgtac ctgagagtga acggttctgc
    15961 cattcgttga ccatcgggtc taactgctca gtcaggctag aaacaaaaga tttcgataca
    16021 gattttccac atagctcttc aacaatcttt gaaactttac gtgtcgaaac gcccgaaaca
    16081 tacatctcaa gcattgaagc gagcagtgcc ttttcatttc gctgataacg ctcaaacacc
    16141 gtcggtgaaa attcaccatc acgtgttcta ggcactttta attcgagtgt acccacacga
    16201 gtcgtaaagt ctcgctcata atagccattt ctttgactct gacgactttc tgaacgttca
    16261 tagtcatcgg cttgaatata ttctgttcgt tgattttcca tcaattggtt gaaaacagtg
    16321 gttaaaatat ttttagaaac atcatctttt accgaatgtt caataatact ttgaacctct
    16381 tcgttgttca gtgtaaaatg tacttgggtc atgtaacgtc ctcctgggta tgtttttgtg
    16441 gttaaaaaca ttgtaccgta aaagggctgt tacatggcct tttatctttt acacaattat
    16501 atggacttta tcgaaacaga ctaaaaacag tgattacgca gataaataaa tacgttagat
    16561 taattcctac cagtgactaa tc
//
LOCUS       DAZKCH010000059        16167 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000059 DAZKCH010000000
VERSION     DAZKCH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.059"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..424
                     /gene="scm"
                     /locus_tag="ACG84X_001997"
     CDS             <1..424
                     /gene="scm"
                     /locus_tag="ACG84X_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFP9127843.1"
                     /translation="DSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTS
                     STTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSK
                     RALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(579..1565)
                     /locus_tag="ACG84X_001998"
     CDS             complement(579..1565)
                     /locus_tag="ACG84X_001998"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFP9127844.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1588..2154)
                     /locus_tag="ACG84X_001999"
     CDS             complement(1588..2154)
                     /locus_tag="ACG84X_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFP9127845.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2168..2584)
                     /locus_tag="ACG84X_002000"
     CDS             complement(2168..2584)
                     /locus_tag="ACG84X_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFP9127846.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3041..4975)
                     /locus_tag="ACG84X_002001"
     CDS             complement(3041..4975)
                     /locus_tag="ACG84X_002001"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFP9127847.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5277..6212
                     /gene="pplA"
                     /locus_tag="ACG84X_002002"
     CDS             5277..6212
                     /gene="pplA"
                     /locus_tag="ACG84X_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFP9127848.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6302..7405
                     /locus_tag="ACG84X_002003"
     CDS             6302..7405
                     /locus_tag="ACG84X_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFP9127849.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7418..8371
                     /gene="menA"
                     /locus_tag="ACG84X_002004"
     CDS             7418..8371
                     /gene="menA"
                     /locus_tag="ACG84X_002004"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFP9127850.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9185..10531)
                     /gene="gor"
                     /locus_tag="ACG84X_002005"
     CDS             complement(9185..10531)
                     /gene="gor"
                     /locus_tag="ACG84X_002005"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFP9127851.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10665..11918)
                     /locus_tag="ACG84X_002006"
     CDS             complement(10665..11918)
                     /locus_tag="ACG84X_002006"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFP9127852.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(11924..12847)
                     /locus_tag="ACG84X_002007"
     CDS             complement(11924..12847)
                     /locus_tag="ACG84X_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFP9127853.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13068..15560)
                     /locus_tag="ACG84X_002008"
     CDS             complement(13068..15560)
                     /locus_tag="ACG84X_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFP9127854.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15567..16034)
                     /locus_tag="ACG84X_002009"
     CDS             complement(15567..16034)
                     /locus_tag="ACG84X_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFP9127855.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         4746 a         3378 c         2876 g         5167 t
ORIGIN      
        1 tgatagcacg gacacgtcag cttcaagtga cagtacagat actacctcta ccacaagtga
       61 tagctcagat tcatctacca ctacaagtga tagcacggac acgtcagctt caagtgacag
      121 tacagataca tcctctacca caagtgatag ctcagattca tcaacttcaa gcgatagtac
      181 agacacgtcg tctaccacaa gcgatacacg tcatgcaagt gtctccttct caaaaacaag
      241 ttcggataac aggacgaact ttaacttaac taataaaaca agcaatgaca atggaaacaa
      301 atcaaaaaga gcacttccta aaactggaag tcaatcgaat aattggataa cactcgcagg
      361 cgttatatta cttgtaatcg gtttaagaat cacttttatg agttataaga aatcgaaaag
      421 gtaaaaaaat attcaagata aaaaagagca acgtcgctaa cggacgttgc tctttatttt
      481 tgctttttat cataaataca agaactacaa ttcaatttgt caaaaaacac gtagatttcc
      541 ttctgagaaa tttatttacg tatcgaacct ttccctattc agtctttgcg atccaaaatc
      601 agttgggtaa gggaaaagag attctctttt gttcgaagag aggtggcagg taatttcttt
      661 atttccttca aagccttttc tgtgtaagag gccgctaact tcctagcttc ttccacgcct
      721 cctgtatgtt caacgatttt gcgtacggcg tcgacatctt cttctgtcat tgccgctttc
      781 ttctctaaat aaggtagtag ctttggtttg tttttttgca aagagtagat caacggtaaa
      841 gaatagaccc cttgacgcat gtcttctagt acaggtttgc cgatttcctg gctctctttt
      901 gtataatcta aaatatcatc gataatctga aaggccatcc cgatagaaag tccgatatct
      961 cctgcttttt ttgcgaagcg ctcgcttgtt ccactttcaa aagcgccaac agaacaactt
     1021 aattggaaca gttcagctgt cttacctgaa atattttcca aatattcttt tacagaaagt
     1081 tcataattat agcgatcatc catctgccct aattcgccat tcaatacttt ttccatactg
     1141 cgagaattca attggagact tttcaaggaa gtggagtaat cagacaatag tttaaaacag
     1201 cagacaaata aatagtctcc tgcatagaca gaaacgacat taccaaactg actacggata
     1261 ttaggctgac cacgtcgcag atccgcttca tcaacgatat catcatggat cagtgtggcc
     1321 gtatggagca tttcgataga agctgccaaa gcgatggctt tgtctcgatc ttgctctggt
     1381 ccaaattgtg agaacaatag ctgataggca ggacgcaaca gctttccgcc ggcatggatc
     1441 gtttctttga ttgcttgttc gacaggtttg tttttcaggc ggacagtttc ttccatccgt
     1501 tttagtgttt ctgtcaattc tttacttaaa gcaggatagt tttcccacat tggatgtagc
     1561 ttcataaaaa aactccttgt gtgacgatta ttttttggta aacattgggc tccatttttg
     1621 tttggttccc tgctcataat ctttttggaa tcgttgaagt gtctgcacat gtcgtaaaag
     1681 ataattcgct gcgatcccga ttgcaatccc tgataaaatc cctaaaactg aaaggactgg
     1741 caagtacaac atgactgtcc atgattgtgc aatgaaagaa gccatcaaaa gctgtccgac
     1801 attatgcatg aaaccgccgg ccgcactaat tccgatgata ctgacacgtt ttggtcctaa
     1861 ttgcttgacc aataacattc caaaataact aagcaaagca ccactcatac tataaaggaa
     1921 tgtggaaatc gttccgccta gcaaagtagt caggaatagt cgtagccaaa gtagtaagaa
     1981 gctgtctcgt tttttcatgg taaaaatggc aacgatcgtg attagattgg ctaagcctag
     2041 ttttgcacca ggcgcaaaag aaaaaggata agggatcata ttttccaata aaccaatgat
     2101 cactccttgt gcaacaagta gcgaaatata aatcattttt tgtaatttac tcatggtgtg
     2161 tgaaggtcta ataaatcaga ctgtcttcgt cacctccatc tgttgaacgg acttcgatca
     2221 ctaatttatg tggcaaacag acgatggttt cgccattttt cgttgcccag cctcgacgta
     2281 cgcagatctg gtcatcgcaa tctgcttctt ttatccgtac tcgatcgcca tctatctcga
     2341 tcaagttata atctccgtgt tcatctttgt aagtatatgt gttgctctct tctccagcca
     2401 tcaaagggaa tgttttgatt tctgtgccat ccacacgcag taccgcttct ttttctgctg
     2461 ttgcggtgtt ttgctgaaga ccaaaaatca tgactggtaa aaaagaaaga acagtcaaaa
     2521 gcaaaataat aaaaacatcc caaggtttga gcagactttt ttcagcaaat tctttaaggc
     2581 tcatttttgt tctccttttt ccagattaac tcacccaatt ttagcataaa aacaagaggt
     2641 tgtgacacct gtgtcttgct ttgagtaata agaacgaaga atagaaaaca gctttccatg
     2701 ttttctaatt ctttgggctt attaccgaga agcagcaggt ggaacaccgt ttataacaag
     2761 aggttgtgac agaagtgggc aacttcaaga aataagaagg aatttacgaa aattactttt
     2821 caagtttttg tgaaatttcg gcttattttt cgaagaagct acttctggaa caccgtttat
     2881 aacaagaggt tgtaacagag gttgtgacac ctgtgtcttg ctcatggagg cttatctcgg
     2941 gcatcttatt cctttaattt tacataaaaa ggaggctgtg acggtttgtc tcagcccctt
     3001 tctattgaaa tcttgcattc aaataacgtt ctttatctat ttatttcttg ccgtactggg
     3061 aacttggtct accgtaccac caattaccta gtgtacgttg tagccatgga attacccagc
     3121 gatccaaccc aatcgcacgt ccggaaccgt tcatcaatgc gaaagcaaca aaaatgaacc
     3181 aaatgtttac ccagtaaaac atgcctgata agcagaacgt gatcaccaat acaatcgttg
     3241 tcgcactgca tagccatgtg aataatccag caatcaatgc taatgccaag gcaatttcaa
     3301 agaataccat gaatttttgg aagaacattg ctacatcatt gtttggcatg atcacttgca
     3361 tgatctttgt gaaccagtct ggtgacttct caatcacagc cattggttct tcaccgtatg
     3421 cataactcaa accaaaatgt gcagcttgag tcgctgcttc tccggcactt gcccctgctc
     3481 cgctggcagc tgtggttgca tcaccagcag cagaagcacc actggcaaca tctgttacat
     3541 tgtattccca tgtccaaggg aacacactgt ttccagtgaa ccatgatcct tcaccaaacc
     3601 aagtacttgg tttgaacact tcaccattcc caatgatttt tttggaagct tcaacgaacc
     3661 aaactaaacc atagaaaata cgaagtggca cactccataa gacattgccg taacgagaag
     3721 aatgtcctcg agtcacgttg cgatcatctt tgatatggaa aaactcatgc attaaatatt
     3781 ggaacatata ataaccagaa cgaatatcaa agaagtattt caaattcacg atatgtttca
     3841 ttacgatagc taaaaatccg cttaaatgga tcttatcaaa taggttagct accccccatt
     3901 tggcaccaat agaaaccata aatccttgat agtttccttt aaatttatgc ttttctccgc
     3961 ctttgatcga agccacgata ttcgctgcgg ctgtgtgtcc tgtttgttca gcagcttgaa
     4021 cgatctgcgg tgtcggtgtt cctgggaatt cttcataaaa gactaaatca ccaatgatat
     4081 agatgttttt atcttcgtag ccttttgcct gcatatattc attggcgatc aaccgctgtc
     4141 cgcgtgctga ttctaatcca aagtcagcag cgtcagaagt tcctttgaca ccagctgtcc
     4201 aaatcagtgt gtgagtcgga atgttgcgtc cgtctttcaa tttgatatga tcagcagcca
     4261 cttctacgat tggtgcattc aataataatt ccacgttgtg cttacgcaaa tagcgttcag
     4321 cttttgcagc atcatttcga tccaacatat tcaagatcgt cggcattgcc tctacgacca
     4381 tcagtgtgat ttcgtttgga tctaatttat aatctttggc taggcgattt ttccagtcga
     4441 tcagttcccc aatcatttca ataccggtaa atccagaacc acagacaacg aaagtcagca
     4501 tggctttacg cagttcatca tctggttcca atgcagcttt tgctactgtc ttctcaatat
     4561 gttcccgaat ccttacagaa tcttcaaatg accaaagggt gaatccgtgt gctttgacac
     4621 caggtgtacc aaagtcattc ggctctccgc ccattccaag gatcagctga tcaaaaggat
     4681 aggaacctaa tttggtcttg acgatttttc gttctttatc gataccgatt acagtgtctg
     4741 tgacaagttg tacattcttt tgacgagcaa acaaatgctg cagatcgtat tggattgctt
     4801 ctggttctac acgtccgcca gctacttcat gcaactcggt catcatagta tggtacgaat
     4861 gacgatcgat cagagtaatt gctacatctt cttttttcag tttctttgcc aagtattttg
     4921 tagctgaaac accggcatat cctgctccta caacgacaat attttgcttt gccattgatc
     4981 atccgctcct tatagactat ctatataatg aatatatgat aattctttta gtttgatact
     5041 tattacacaa tctccatata ttatatagat gttctgttct tttgtctaac tccttttgga
     5101 tttttttcaa attttaaaat aaagcgtttt ttcacgaaat ttgctgaaag aaaacgtttg
     5161 aaatattaca tgggttattt atcaaaaata gttgacttat aggctaaaaa gattagaatg
     5221 tataatgaat cacaaagaaa aattgtggac tagaaatgga atggtggggt attaaaatga
     5281 agaaaaaacg ttttgtaact ggatttgccg tattagcatt ttcagctcta gtgttaggcg
     5341 cttgcggcgc agatgacaac ggaagctcaa actcttcttc tgaatcatct acagcacaat
     5401 cttcgactgc aaaaagcaca acagaatcat ctgcaaaagt tgtagctggc ggagatttgc
     5461 aagacggcac atataaatta gaagaaaaaa attattcaaa tggttaccgt gcagtctttg
     5521 aaatggttgt aaaagacggc aaaatcactg aatcaaaata tgataacgtc aatgaaaacg
     5581 gcgaatcaaa aacaaaagat gcagaataca acaaaaacat ggaagcaaaa tctggcacaa
     5641 acccagaaaa atacattcct gagttgaatg accaattctt aaaagcacaa agcgcaagcg
     5701 gtgtggaagt cgtaactgga gctactcact catctgaaag cttccaaaac tacgcacaac
     5761 aattgatcca agctgctcaa gctggtaaca cagatacaat cgaaatcgac aatggtgctg
     5821 atttgaaaga cggcacttac aagcttgaag aaaagaacta ctctaacggc taccgtgtgc
     5881 aattcgaaat gacagttgct ggcggcaaag taactgaatc aaactttgat tatatcgaca
     5941 aagacggtaa atcaaaacaa gatgatacag aatataatga aaatatgaaa gcaaaaagcg
     6001 gtacagaacc aaaaacttac atccctactc tgaacgacga attcgtcaaa gcaatgggcg
     6061 aagaagatgg ctcacctgct aatgtagaag ttgttacagg tgctacacac agctcacatt
     6121 cattcatcat gtacgcacaa caattagtga atgcagctga aaaaggcgac actcaaacaa
     6181 tcgaagtaga taatatcgta acagaaaaat aatcacataa tcatactaat aaaagttgga
     6241 gggtgggacg atagccagat taggcagtcg tctcaccttt caaaatgaag agaggaaaaa
     6301 gatgcggaaa aaactactat tttccttaat cacactgggc atctctttta tggtgctaac
     6361 tggctgcagc aactcagcaa ataaaacaac cactgaaagt tcagcagcta ccaagatatt
     6421 gaaagatcca tattctgatg aacagttctt gttagggact tacgttcgta tccgtgtgta
     6481 tgatgaaggc aaagaatcag cattgaaacc tgccttcgat cgagtaaaag aacttggtga
     6541 taaaatcacg atcaatcaaa aaggttctga gatcgatgaa gtgaatgagc aagctgggat
     6601 caaaccagta aaagtttctg atgacgtcta cacgttagtc aagcgggcct acgaatatag
     6661 ccaagattct caaggcggat tcgatatggc gattggtgca atcacacaat tatggcgaat
     6721 cggttttgat gacgccagaa aaccttccca agaagaaatc gatcaggcat tgaaattagt
     6781 ggattatcat aagatcgaac taaatgacaa agaaaaaact gtttatctaa aagaaaaagg
     6841 aatgatcatc gatttaggtg caatcgccaa aggttacatt acggacgaag tagtgaaagt
     6901 cttgaaaaaa caaggagtga ccactgccat cgttgacttg ggcggtaatg tctatgtctt
     6961 aggccacagc ccaagaggcg aaaaccaaga ctggacagtc ggcatccaag atccgaacat
     7021 ggctcgcgga tctgttttag gttctattaa agaacggaac aaaacattag ttacctctgg
     7081 aatttacgag cgttatttag aagtagatgg caaaaaatac catcatttgt ttgatccaaa
     7141 aacgggttat ccgttcgaca atgatatcgc aagtgtcacg atcataacag ataaatcaat
     7201 tgatggtgac gggttgtcta cagcagtctt ttcaatgggt gtgaaaaaag gactggaata
     7261 cgtcgaaagc gaattgaata acgggacgga agcgatcttc gtgacaaaag acgataaagt
     7321 atatgtgacc gatccaatca aagacacctt caaattatcg gaggactccc attacacgat
     7381 gggtgaccgt tctgaactaa aataaggagt acgaaccatg acactaaaaa tctttttaga
     7441 agtagttgaa atacgaacaa aggtggctag tgtatttcct tttgcggtag gggtattatt
     7501 ctctatcgct ttttttcatg agatacattg gctaaacact tttttatttt ttattggaat
     7561 gctagttttt gatttagcga ctaccgctat caataattac atggattatg aaaaggctca
     7621 ttctgaagta tataagtatg aagaaaatgt cattggccgc agaaatctat ctcctgtatt
     7681 gattcgaaac atgattttag ctatgattgc atttgttttt gttatcggcg ttattctaac
     7741 gatcaatacg ggttggcttt tacttttgat gggatttatc tgttgtttta ttggagtatt
     7801 ctatacattc ggaccgattc ctttatctcg aatgccttta ggggaaattt tcagtggggt
     7861 gactatgggc cttggaattt ttgccatggt cgtttatgtc aatacattcg gttcagatgt
     7921 ctatgatctg acagtcaact tttcatctgg acaatttgct ttggtaggaa atctttgggc
     7981 tatagcagca atcgtattag cttccttacc cttggtgttt acgattgcca atatcatgtt
     8041 ggctaataat ttgcgggatc ttgaccgtga tattgaaaat catcgctata cactagtttt
     8101 ttatatcgga cgtcctgcgg gaacagtctt attccagcta ttgatgtatg cttgctattt
     8161 cgtgatttta atggggttgt tgagcggtat ctatgaatgg ccgatcttgg tcaccttctt
     8221 gaccttgcca attgtgaaga agcatttgga tcaattcaag caaacgttac cccagcctat
     8281 cagtttcagc tattccatca aaaatatggt cttattcaat gccagttatg tattggggct
     8341 attactaaca atcattatgc aagccattta acagcatgaa gaggttgtga aaaaactgcc
     8401 ctgcatcaag taataagaac agccaaataa aaatagctcc ttatattttt cgtttggttg
     8461 ggcttattac cgcagatgca agcttttgaa caccgtttat caggaggttg tgaaaaagtc
     8521 gcttagtttc gagtattaag aaaaattttg tgaaaatggc tttccacatt tttgcataaa
     8581 tttggcttaa taccgagaaa ctggcttttg aacaccgttt atcagaggtt gtaaaatcag
     8641 tgttttgtcc tgagtattag agaaacaaat ggaaaaatag ttcctcatat tttgccgttt
     8701 tttgagctaa taccgaagga cagctgattg aacactattt gttcggaaaa agtgactaac
     8761 tatgacacaa tttttttcac agtccctttt ttcacttgat ttgattcgta ccagcgaact
     8821 tgacgagaac tttcttggtt tggtaactat atggtattct tttaacatcc tcgtttgctt
     8881 cttctaattt atttatacaa agtcacactt ttttaaacat ctgttcttcg atacatttct
     8941 atttctttta aacatcgata ccaatatttt gaacttaaga gtgcatacca aatggattca
     9001 tttactcttc gtcagttacg aagataatca aaatctccaa cttccctact tatttcgttt
     9061 tgagaattat cgaagcaatc ttacataaat aactaaaaaa caaaaaacca gaaaatcagt
     9121 atactgattt tctggtttta catggtttgt tcaataaaaa gctgttggaa ctgttaatat
     9181 taaattatcg catcgttacg aattcttccg ctcctgttgg atggatggct actgtattgt
     9241 caaagtcttc tttagttgca cccatcttga tagccacggc aaaaccttgc agcatctcat
     9301 cgacaccaac accaatagca tgtaagccga cgattctttc ttcttttccg acacagatca
     9361 atttcatttc gcatttttgg cgataatcat ttaatgcaaa gtacattggg gtaaagcgtg
     9421 aacgataaac tttcaattca ttttcgccat atttttccaa tgcttcttct tctgtcaaac
     9481 caattgttgc aattggtgga tgcgtaaaga cgactgtcgg aacaagttta tagtcaagat
     9541 aagaatcttt ctttccatta aataaacgtt ctgataaacg tctaccagct gcgattgcaa
     9601 caggagtcag atctaattta ccgatcacat caccaacagc aaaaatatgt tcatccgttg
     9661 tattttggta tttatctact ttgataaacc cttttttgtc caattccaca tttgtatttt
     9721 ccagacctaa tttttcggta ttcggtacac gtccaccggc aaaaagtaca caatcaccag
     9781 ttaaggtttc accattttca aatagcaccg tatattcgtc attgttttta gtaatttctt
     9841 tagcaatatg atgtgcgtaa gtttttattc cagcttcttg gtacatttgg atcaaattgt
     9901 ccgaaagcat tttatcaaac gttctaagtg gtcgttcttt tcgatatgcc cacatgactt
     9961 cactacctaa accacgaaat acacctgaaa gttcagccgc aatgtatcca gcacctaaaa
    10021 cgattgctct cttaggtaac tctgttaatt caaaaaatcc atttgaatca attgcgtatt
    10081 ctccaccagg aatggtcatt ttacttgcac ggcctccagt agcgatcaag attttaggag
    10141 cacgataggt ttcaccgttt acttcgatcg tttgactatc gataaaagta gcgtaacctt
    10201 ttatagcctc gacatgattg ctatctaatc ctctttgata agcaccgtgt agaaaatcaa
    10261 tatatttttc tcgtctttct actagaccgg cgaaatcaac attttttaaa tctgcttgga
    10321 taccgtaact tgaggcatct cgttcaattg tttccaaaat cgtacttgct tgccacataa
    10381 cttttttagg tacacaaccg acgttgacac atgttccgcc caattcattc gcttcaatca
    10441 gcaaaacttt tgcgccatgc atccctgctc tgtttgctga agcaataccg ccagagccgc
    10501 caccaattac gatgtaatca tatatttgca ttttgttcct ccttattgaa gagatcaatc
    10561 aaaaccttta tttaacgatc ctttttctac agaaaacaag tgtaacactt ttcttgaatt
    10621 ttgtatgcga agatgcttaa aacagggata tatcagcttt ttccttattt acgttttcgg
    10681 atcatatctc caggtttcac cggctgtgcg actggcatag ttaaaatcat cattggattt
    10741 ggtgctcggt caatggattc gccttcttca ttatgcataa cttcaacggt ttgactgaaa
    10801 tgactgaatc ctggaccata aaattcgatt tcatctccta cagaaaacaa gtttctctga
    10861 cgtatcgtag caatctgtgt tgcctcatca taagataata cttcaccgac aaatttatat
    10921 actgggattt tacgacgttc accgaataat tgttcgtttt cagttggtgt attgtagtaa
    10981 aaacctgtag ctaattctcg ttgtgctact ttccataact cgtcgatcca ttcttgcttg
    11041 cagacatagt tttcaggatc ttccatataa ctgtctacag ccgctttata gacatttgac
    11101 accgtagata cataatggat cgatttcatt cttccttcga tcttgaagct gtctacgccg
    11161 ttttcaatca attctggaat atgttcgatc attgacatat ccactgcact catcgagaat
    11221 tcttcttcca cttcgcctgt atcagttaaa ctgtttcgtt cttgaccaaa aggcatatcg
    11281 aacaatccat acttccagcg acaagattga gaacatccgc cacggtttgc atcccgcatc
    11341 gacatatggt tggacaatgt gcatcgacca gaataagaga tacacatggc accatggata
    11401 aatgcttcga tttcggtatc cgtattttta cgaatctctg ccacttcctc cattgaaact
    11461 tcacgagcta aaacgacacg ttccaaccct tcttctttcc agaattccaa tgtctcaaaa
    11521 ttagttgctg aagcttgagt ggataaatgg atcggcagac ctggggcttc tgtcgcacaa
    11581 atttcgatca aagctggatc agaaacaatc actgcagaaa taccgacatc acgcaaactg
    11641 cggaaaaatt cccctgctcc atcttcattt ccttcatggg tgaccatatt agcagcaacg
    11701 tataccttcg catcatgttc ttttgcaaaa gcaactcctt cagccatttc ttcataagta
    11761 aaattacctg cacggcttct taaaccatat gcattcccgc caatatatac tgcatctgct
    11821 ccataatgga tcgcggtttt taacttttcc agtgttcctg ctggcgctag gatttctggt
    11881 cgtttcaatt ttctttttac tgtcatttct ttcatcatac tccttatttg atagcagaag
    11941 gatcaatata aaagaatcct gtatctaatt cacggttttc aggatgcaat ttactgattt
    12001 cgctagtcat tttttccgct ttttcttgat cccagctacc ttctaaaatt tgtttttttg
    12061 cttcggcgaa tagtcgagtg atgtttacga atttttcgcc tggagtaaat aatccgtcca
    12121 atttccatgt acagtaatga tgctgataaa gttcattcaa ttcattcgag agattcagat
    12181 cattgctggc aaaaatatgt gtgccatgac tatcttcata aatagaataa tgtgtctctt
    12241 cttttttagg ttccgagata aaaagacctc tttcacgatc tttttgttcg tcttgtttcg
    12301 tatagttata gtaattctgt agcagtggac gtttggattg atggatgcat gtagcaccat
    12361 acacaagggt ttctacagga atatcgagtt tttcttccat cgccttcatc tcttcaaaag
    12421 gaacttcacg agcaagtact gctccaactg cgcctttttt cgcccagaaa ttgatttgac
    12481 gtgcgctcgt tactaatgtt tcagcatcat aaatatacgg tatacgcaat tcaggatttt
    12541 ttttcatcgt ataaataata cctgtatcac caactgtgat cacatctacg tttatttctt
    12601 ttaaaaaagc caaatattca ggtacatttt tcattttttc aggatgaatg atcccattta
    12661 cagcaatatt cgctttttta ccatacttgt gtgctaattc taccaattgt cgctgttctt
    12721 ctcgtgtaaa tgaagcaggc agacgcaatc caaattgctc ttcaccgaaa tatagtgtat
    12781 ctgcacctgc agcaagcaac tgttctgctt gttcaatagt ttctactgtg gttatgagtt
    12841 cgatcataat tttctcctcc tacaacttca taatagtagc atagctctaa aaactttcca
    12901 atacttcttc tatttaaagt cggatttttg aaaattattt cacaaaaaat caaaataaag
    12961 ttcgatatat tctgtccaaa tataaaaaga gattgtgaca aaaatcttgt cacaacctct
    13021 taatcaagtc ttactattat aaaaattcag ctacacaggc caagtaacta tagggaacct
    13081 actgtttcct ttttaggtcc gcgaacattc aatgtgatct taccttttga agcacctact
    13141 gttacgtggt cacctaaacg aatttctccg ccaagcaaag cctcgctcaa tcgatcttca
    13201 atttcttttt gaagtgcgcg acggattgga cgtgcaccat attcaggatc aaatccagct
    13261 ttcccgatca catcgattgc agatggtgtg attttcactt gaatatcttg ttctttcaat
    13321 cgtttgataa tcgctttgct catgatttgg acgattgtat ggatttcatc tttactcaat
    13381 gaatggaaga cgacagtctc atcgattcga ttcaagaatt caggtcggaa agctttcttt
    13441 aactcttcta agatacgttt ttgcatggct ttgtgatctt tagtaacatc ttggacattg
    13501 aatccgacat ttttttcttc tcgaatttgt gtcgctccga tatttgaagt cataatcatg
    13561 attgtatttc taaagtccac ttttctacct ttagaatctg ttaaatgacc atcatccaat
    13621 acttgcagaa gtaaattgaa aacgtctgga tgtgctttct ccacttcatc taagagaatc
    13681 actgaatatg gtttttgacg aattttttct gtcaactgtc caccttcatc ataccctacg
    13741 tatcctggag gagacccgat taatcggctt gtactgtatt tttccataaa ttctgacata
    13801 tcaacacgga tcagggcatc ttcacttcca aacatgactt ctgaaagtgc tttggccaat
    13861 tctgtttttc cgacaccagt tggtccaagg aacatgaatg aaccaattgg acgatcagga
    13921 tctttcaatc cgcttcgtgc acggcggatc gcacgtgaaa ctgctttgac agcctcatct
    13981 tgaccaacga cacgttcatg cagaagtcct tccagttcta acaagcgttc gctttctttt
    14041 ttctccaact gctgtagagg gacaccagtc cactccgata caactgtagc aacatcttct
    14101 tctgttacac gatcagaata accttgctcc tgttttgctt caattgcaga aactttttgc
    14161 agctttttac gtagtgcttt ttcttgtctg cgtaattgag cagcattttc aaagtcttgt
    14221 ttttggatcg ctgcttcctt ttcttgtact agttcatcga tttctagttt gatcacagtt
    14281 gattttgtta agtgatcggt ttgatccaaa cggactttcg ctgctgattc atcgatcaaa
    14341 tcaattgctt tatcgggtag ttgacgagaa gtgatataac gaacagaaag attgactgct
    14401 gctcgtacag cttcatctgt gatctccact ccatggtgct cttcatatct tgtacgtaat
    14461 ccttgaagaa tcacttctgc ttcttcagga gttggctcat ctacttgaat gcgagcaaaa
    14521 cgtcgctcta atgcagaatc tttttcgata tatttttgat attcatctag ggtcgttgct
    14581 ccgatcgttt gtaattctcc tcgagctaac gccggtttca agatattcga agcatcaatt
    14641 gctccttctg ctccacctgc accaattaag gtatgcaatt catcaatgaa taagattact
    14701 tgaccatcat tatagatttc gtcgatgacc tttttcattc gatcttcaaa ttcaccgcga
    14761 tatttcgtac cagcaaccaa agatcccata tcaagcatca tcaggcgctt ttcttgcatg
    14821 tcttctggca cttcacctaa aatgattttt tgagctaacc cttcagcaat ggctgttttg
    14881 cctacaccag gttcacccac cagtacaggg ttattctttg tccgtcggct aagaatctgg
    14941 ataagccgtt tcacttctct cgaacgacca acaactgggt ccagcttgtt ttcttttgct
    15001 aatttcgtca aatcacgtgc taatgaatct agcgtaggtg ttccttgcgg tgtttgccgt
    15061 ttatcttgta catttacatt tctacgacga ttcattcctt ttccagcaga atcaccagct
    15121 agccccattt tttgtttcag aacttgacgg gcttttgaaa ggctgatacc taagttgatc
    15181 atgattcgag tagccatgat actttcatct tttaataagc tcatcaaaat atgttctgtt
    15241 ccaacttttt gagaaccagt tttcttcact tcgctgctag ctaaagcaaa aacttgtttc
    15301 attcttggtg aatatggaag aaagactcct ttagggtaag aacggatacc accataacca
    15361 atcagatgtt caatttcttc ataaatttcc gtttcattca aatccatttc acgtaatact
    15421 tttccagcaa ttccattttg ctcgaccact aaggctagta aaacatgttc tgaactaact
    15481 gattgatgtt tcaaccgttt tgcttcttct tgtgcaattt ctaatactgc ttgggctctt
    15541 tcagtaaaaa gttcttccat ctaatctcac ttcccatctt cataacttaa acgttccaga
    15601 aatgctcgga gaatccgagc acgtgtatga tcttcatatt cattgaaatt caatgtgttt
    15661 tttgcaattg cactcaacat caagtttcct tctttttttg taattatttg gtcttcataa
    15721 agtttttgaa taatagcaaa agcatttttc tcactgattg tatcatcaaa taactgattt
    15781 atctgctcaa gtaattgttt tttatctgaa atccttactt ttgcaattcg tatataacca
    15841 ccaccaccac gtttgctttc tactagataa ccacgttgga tggtaaaacg ggtattaatc
    15901 acatagttga tttgtgaagg aacacagtta aagaggtctg ccatttcaat ccttcgaatc
    15961 tcgatcattt cactattttc cagaattttc tttatatatg attcaattaa atccgaggta
    16021 ttctgatgtg ccatcttatt cattcccttt gactaatatt gaccttaatt ataacgaatt
    16081 tgataataga aagaaagaag aacgcttttt gttaaataaa tcctttagaa tcaacaaaaa
    16141 aaaatacgga atatactatt ccgtatc
//
LOCUS       DAZKCH010000060        15901 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000060 DAZKCH010000000
VERSION     DAZKCH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.060"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            203..1018
                     /gene="thiD"
                     /locus_tag="ACG84X_002010"
     CDS             203..1018
                     /gene="thiD"
                     /locus_tag="ACG84X_002010"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFP9127856.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1347..2798)
                     /gene="cls"
                     /locus_tag="ACG84X_002011"
     CDS             complement(1347..2798)
                     /gene="cls"
                     /locus_tag="ACG84X_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFP9127857.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3139..5805
                     /locus_tag="ACG84X_002012"
     CDS             3139..5805
                     /locus_tag="ACG84X_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFP9127858.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6169..6921
                     /locus_tag="ACG84X_002013"
     CDS             6169..6921
                     /locus_tag="ACG84X_002013"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9127859.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(6943..8097)
                     /locus_tag="ACG84X_002014"
     CDS             complement(6943..8097)
                     /locus_tag="ACG84X_002014"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFP9127860.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8282..10723
                     /locus_tag="ACG84X_002015"
     CDS             8282..10723
                     /locus_tag="ACG84X_002015"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFP9127861.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(10880..12154)
                     /locus_tag="ACG84X_002016"
     CDS             complement(10880..12154)
                     /locus_tag="ACG84X_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HFP9127862.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTLEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRDTEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            complement(12562..13266)
                     /locus_tag="ACG84X_002017"
     CDS             complement(12562..13266)
                     /locus_tag="ACG84X_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127863.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(13453..13698)
                     /locus_tag="ACG84X_002018"
     CDS             complement(13453..13698)
                     /locus_tag="ACG84X_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127864.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(13715..14566)
                     /locus_tag="ACG84X_002019"
     CDS             complement(13715..14566)
                     /locus_tag="ACG84X_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFP9127865.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            14732..15736
                     /locus_tag="ACG84X_002020"
     CDS             14732..15736
                     /locus_tag="ACG84X_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFP9127866.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         5074 a         2822 c         3326 g         4679 t
ORIGIN      
        1 aatagtggtt atttattatt agaatagcga atacaaataa acgaccacta ttttctgatt
       61 tattgcaaat gttttttcaa ataaatttga ttaccaagaa aaggtagtgg tatatttact
      121 gagggatact ttgaaaaaca tatgatagaa acagtaacag tattatgaaa aatcttttta
      181 taaaaatgga ggaatcgatt tgatggaaga tcagtatgta caagcaatga cgatcgcagg
      241 atcagatagc gatggaagcg cagggatgca agcagatatg catacattct ttacaagaaa
      301 tgtttacggt gtttctgtca tgaccgcatg tgttgcaggt aattcttacg gaatcggagc
      361 aagtgtgaca ttgccaacag attttatcga caaagaattt gaactgattg cgaaggactt
      421 tcaaatacgt gcagctaaaa caggtatgct agcagattca aagttgattg agacagttgt
      481 aaaaaattac caaaaatatg attttggacc attagtcgtg gatcccgtaa tcgtaacgaa
      541 acatggaaat cttttactag aagaatctgc tttgcaaagc ttgaaagaaa agcttgtccc
      601 tttggccgaa gtactgacac ctaattttta tgaagcagaa aagctgactg gacggacatt
      661 agcagctgaa gaagattttg tgcaagcagc aaaagaactg caagatatgg gtgcaaaaaa
      721 cgttatgatc aaaggacatc atgctaaaaa tgcgcagcaa gaaacagtca atgactacgt
      781 attgttcgaa tcaggaaaat cattttggtt aaatgcacca ttttatccta ccgaccggat
      841 caacggaact ggcgattcgc tatctgcatg tattgcagct gagttagcga aaggaaaaac
      901 agttgaacaa gcgatccgat tggcaaaaga ctatgtaaac cgtgcaattc gtgaagaaat
      961 aaatgtaggg cacaaatatg gccccatcaa tcattgggca gctggtgaat tagagtaaaa
     1021 gaaagaagtt gtgaaaaagt tgccctgcat caagtaataa gaacagccaa gtaaaaacag
     1081 cttcttatgt ttttaacttg gttggactta ttaccgcaga tgcaagcttt tgaacaccgt
     1141 ttaagaaaga ggtcgtgagc ctgccgtcca gctccgagtc acaaggaaca agttcaaaaa
     1201 acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttggc aggagaacac
     1261 cgtttgttcg gaagaaggga ctgtgacaag atttttgtca cagtcccttt aatcttagta
     1321 tatttttctc tacttgaata aaaaaattat aggattggag aaaataatcg agaaatttgt
     1381 tgcttgaata atagccagtt agacatttcc ttgactgttt cagttgtcat ggatgaacaa
     1441 tgtgtctcat cttctttgaa ctgagtagca agttcttcta aaaactcagg atcgtaaatg
     1501 acagcacttg tttcaaaatt caatcggtag ctacgaatat cttgatttgc tgaacctacc
     1561 atgcagattt catcatccat tatcaatgtt tttgcatgga ggaagccgtt ctcatagaca
     1621 aggatttgta cattttcctt gatcagctgc cgagcataat attgtgttgc tcgataaata
     1681 aaaggatgat ccggtttgtt gggaatcatg attttcacat ctacaccaga ggcagttgcg
     1741 atttttaaag cagcaatgac actttcatca ggaacaaggt aaggtgtctg tatccaaaca
     1801 cgttttttag cagaagtaat caatttgata aatgaaagct tgatttgttc cctttcgtta
     1861 ttcggtccgc ttgaaacaag ctggatggat gtatcagcaa gcttagattc atctcgatct
     1921 gcttttttaa agaaataatt caaatgatag ccgacctttt tttcttcagg taccgagacg
     1981 ttccagtctg ttaagaagcg aagctggagc aaagaagaag cggcaccgaa aatccgtata
     2041 tgcgtatcgc gccaatagcc gaattttttt gttgtattta catattgatt ggcaatattg
     2101 aaaccaccgg tataactaat ctttccatcg atcacaacga tttttcggtg atcatggtaa
     2161 ttcaatcgga aacgaagtaa tgccctttgt gaggtaacaa atgtatggac atgtccacca
     2221 tttttgatta gacgattgaa atcttttgct tttgtgccat gagagccaaa tgcatcatat
     2281 aatattcgaa cttccacgcc ttctgcggct ttttcttcta aaacatgtaa gacttgctgg
     2341 ccgatattat ctgtcacaaa tgcgtaatat tcgatatgga tcgaatgttt ggcttttttt
     2401 agatcttgaa gcagtgaatc caatttctct tgtccgtctg tgagaagagt gacagaattc
     2461 attcttgtca gcggcatacg atttaatgaa gagaagaagt caacaaattg ctgtttgtct
     2521 ttatcgccca tgtcaggatc gtaatgttca atggtatctc ctctaaaaga ctgaaagttt
     2581 tctaattctt tcaagtcact ttgtcggaga tagaattttt tcttatccgt taatccacgt
     2641 ccgaaaaata aatataatac aaagcccacc ccaggaaggg caaacaatac taagagccat
     2701 gcccaaatgg ctgctacatc tcggggtttg atcaaaatag ccaccaaagc aataagtgca
     2761 tttaatagat aaagggcggt tataatacta gataccacaa aaatgttcct ccttacatac
     2821 aataacatta gtatagcatg atagaagaaa gaagcctacc aaggtgaata tacttttcac
     2881 tcctttcatg aaaatgtagg taaatcgggc taaagtagtt gctttttgta ggttaataag
     2941 gtaggatatt agtacagttg aatatctcct taggggagta accggcaacg tttgttgcga
     3001 taatatcaac agtaagttaa ccaaatggtt ttctggtatt gtatgaaatg gtgagaccta
     3061 agacaaatgc gtatttgtct taggtctctt ttttttcaga caggactagg gccaagatca
     3121 aaaaatgggg gatgaaattt ggaaaacaag gaacaagcac aacaagcggt ctataaagaa
     3181 acgatcgact cgttgatgca gcaaacgcag agctcaaccg atggattgag caccacgcaa
     3241 gcgaaggaaa aattagaaag agatggcttg aaccagctaa aagaaaagcc gaagaagcca
     3301 acttggaaat tgttcttaga aactttcaaa gatgcaatgg ttatcgtatt gctgattgtc
     3361 gcactgattc agatggtcat gggtgactac atcgaattct tagttatttt tgcagtattg
     3421 atgttgaatt ctataatcag tgttgtccaa acaaaaaaag cagaaggttc tttagaagcg
     3481 ttgaaaaacc tttcagcgcc cgatgctcga gtgattcgtg atggtaagga aaaaacgatt
     3541 ccggcaaacg aacttgtggt aggagatatc gtgttgttag acgcaggcga ttatgtacct
     3601 gctgatggac gtttactaga tgcgggatca ttaaaagtag atgaaggtat gctgacagga
     3661 gagtcgactt ctgcagaaaa agaagtaacg gatatcacaa gtacggtacc aatcggagat
     3721 cgtacaaata tggtattcag tggaacgatc gtaacttacg gacgcggtaa attcttagtg
     3781 acttcaactg ggaataatac ggagatcgga caagttgctg gccttttgga atcaacaact
     3841 gagcaagtca ctccgttaca acgaggtctg gataaattca gtaaaaaact aagtttggct
     3901 attttggcat tgtctttatt gattttaggt atccaactgt ttcgtattta tcttggagaa
     3961 ggtacaggag atatgactgc agatatcgtc agcgcagtga tgtttgccgt agccgtagcc
     4021 gtagctgcta ttccagaagc attacagtct atcgtaacaa tcgtgttatc tttgggaacg
     4081 aataaaatgg caaaacgtca tgccattatt cggaagcttc cagcagttga aacacttggt
     4141 tcgacaagta tcatctgtac agataagact ggtacattga cacaaaacaa aatgacagtt
     4201 gttgactact ttttaggtaa tggcgatact ggggatttca caaatgaccc ttcaaaatgg
     4261 acagctgacg aacgtcgctt gatcgaaatc agtgttttag cgaatgatgc atcgatcagt
     4321 gaagacggta ctaaattggg cgaccctacg gaagtagcgt ttatcgactt tagtgaaaaa
     4381 ttaaaccagc cttatcagga aatccgaaac aactacccaa gacaagcaga acttcctttt
     4441 gactcagatc gaaaattaat gtctactgga cacacaattg ataacaaaaa ttacttgttt
     4501 gttaaaggcg gaccagatat cgtcttccaa cgcagtaaaa aagtattgct aaatggtgaa
     4561 gtcgttccga tgacggatga attgatgaaa aaattccaag agcaaaatga agctttttca
     4621 acacgcgcat tacgtgtact agcttttgct taccgtccac ttgataattt tgatttatca
     4681 tttgaagatg aagacgattt gatccttgtt ggtttgcttg ctatgatcga tcctccacgt
     4741 gctgaagtga ctcaggcggt aacagaagca agaagtgcag gaatcaaaac aatcatgatt
     4801 actggtgacc acaaaacaac agctgttgct atcgcaaaac aaatcgggat ttttgaagaa
     4861 ggaaacctgg ctttgaccgg gacggaacta gatgaattga cagaagatca actaaacgaa
     4921 gttttagaaa aagtcactgt ttatgcacgt gtttcacctg agaataaaat tcgtatcgtt
     4981 cgtgcttggc aaaataaagg tcatatctca gctatgacag gtgatggtgt aaatgacgca
     5041 ccagcattga aacaagcaga catcggaatt gctatgggaa cgggtacaga tgtggcaaaa
     5101 gatgcagcag cgatggtatt gacggatgat aactttgctt ctattgtcag cgcagtagaa
     5161 gtaggacgta atgtgtttga taatatcaag aaagctattt cttatctatt tgcaggaaat
     5221 ttaggtgcga tcattgcgat catctttgcc ttagttgctg actggtccaa tccatttaca
     5281 gcattacaac tgttgttcat caatttagtc aatgattcac tgccagcaat tgcattaggt
     5341 acagaaaaag ctgaacctgc tacgatgaac cgcccgccaa gagatccaaa ttcaggaatc
     5401 tttacggaca aaacattgat ttctgtaacg tatcgtggtg tgctgattgg gattgctgtt
     5461 atctttgctc aatggcttgg catgcagcat tcacctgaat tcggtgtagc catgtcattt
     5521 tcaacattga tttggtgtcg gacattgcaa acattcccag cacgttcaaa cacacaaaca
     5581 gctatccaag cagggttctt ctctaacaga agtgtcttac tagctgtagt tgtatgtagc
     5641 gcgctttact gcttaacaat gatcccagga ctgaaagaag tcttctctat cccatcagca
     5701 tttggattga cagaagtctt tacatgtatg ggaatcgcac ttgtgacaat tgttttgatg
     5761 gaaatcacta aattgatcat tgtacgagta caaggaaata aataaaacga atcaacgagg
     5821 ttgtgagcct gccgtttaat tctgagtcac aaggtgcaat ttcaacaaac agcttctcat
     5881 gtttgttgaa tattgtgact tgtgaccgaa gagttggcag gagaacaccg tttaaggaag
     5941 aagttgtaaa atcagcattt tgagctaata ctgagggtca tctgattgga cactgtttat
     6001 tcggaaagag ggactttgac acgactttgg tcacagtccc tttttttatt tatgatagac
     6061 ggaaagccaa tcattttatt attcatcaaa agagatagaa tagataaaag aggagaatga
     6121 tttattccga aaagtgaaaa catataacaa aaaattagag gaaatcaaat gaatgaaaaa
     6181 gaatgggatg aatttgctga agaatattat gaaatccagc aagaatcgca agtaactatt
     6241 gctgaagatg taaaaaatta tctgaaaacg gagaaagtcc tgcctgctga aacagcagca
     6301 gacgttgctg gaggatctgg cagatttctt tccttagcaa aagaaattaa tcgctatgat
     6361 ttgatcgatt tttcttcagg aatgctagaa aatgcaaaaa aagaagcaga aaaaaatgag
     6421 ttgccaaatg tttcctttat caaacagtcg ttagaagaat ttatccaatc aaatgagaca
     6481 tatgaaatgg tttttacagc agcaaatcca gcattggtac atcttattca attagaaaaa
     6541 ttgatgaaaa agtcaagcaa atggtgcgtg ataatcagag tagtggaatc aatcgatgat
     6601 gttttttatc ctatcgaaaa gcaactagga atgatagaag aagatcctaa tacatcgcca
     6661 gttgtaatgg atcaatttga aacatactta attgatgaag gattcaaagt gaagaaaaaa
     6721 gattttactt attttacaca ggaatcaatt actgaagaat tgatgaagct atactatgac
     6781 gcgtacgcaa aagatcctgt tgtgaccagg tacattcgca aactattcag tgaaaaacga
     6841 gaaatcctta gtacgactaa gctgacctat agactgctcc tttggtccgc agataaaaaa
     6901 agaacctttc acgactcgtg aagggttctt tttatgattt tattatattt tgtagtaacg
     6961 aatatcattt tcgatctttg taatcgaaaa aggtacatct gaagtatatt ctgcacattc
     7021 tccgtgttca ggaagcgtct cactgaaaat cgtttcatat tcgtcaacag tgatccgtgt
     7081 tcgagaatct agcatctctt gatgagattg tgcgaagaga tattcttgat agttttcttc
     7141 cagataacct gtaaaaaatt cacttactgc accagaaccg tagctgaata gaccgatgcg
     7201 atctcctggc tgtagtgatt tcgaattttc cagtagagaa gttagcccca ggtataatga
     7261 accagtgtaa agattaccga ttcgtcggct gtaacggatg ctttcttcat agcgagccat
     7321 aagacgttcc tgattttctt cgtctgtttg gtctaatacg ctttgcaatg ccttttttcc
     7381 catcttagta tacggaatat ggaaagcaat cgcctgataa tcttcgagtc ctcgacccga
     7441 caattcttta tgtcgattcc aaactttttg gaatgattcg atatacgtag aattagataa
     7501 aggaccatca acaacaggaa attcgctata atctggacgc cagaaatcat agatatcttc
     7561 tgtcagaaat acgctgtcgt cttcaatcga taaaatacgc gggttttgag tgatcatcat
     7621 cgcaacagca ccgacacctt gcgtcacttc accaccgctt gccaagctgt aacgagcaat
     7681 atcacttgct atgactagta cttttcgttc tggatgattt ttgacatatt ctttcgccat
     7741 gtgcaaagct gcggtgccac cgtagcaagc ctcttttact tcaaaagaac gagcaaaaga
     7801 ttggattttc agtaaatggt ggataattac cgcactcgct tttgaatgat caatcccgga
     7861 ttctgttccg acgatgacca tgtcgattag ctcacggtct ttttctgtta cgattttgct
     7921 ggcagcattt gctcctagtg taatgatgtc ttcatttgca cgattgactg ccatttggtc
     7981 ttgaccaatc cctatatggt attttgcagg atcatcccca cggctttctg ccaactctgt
     8041 catatctaaa tataaattag gaataaaaaa ggaaagacga tcaatcccta ttttcatttc
     8101 aacacctctt tacttatgat aaaaaactta ctttactaag gtatcataaa aagattaaaa
     8161 gaaatataaa aaagagaata tttaaggatt gttaaaattt aatcttagaa aaaaataact
     8221 ggaacaagag ctatttgttt ttacagcaaa gaatggtata tttttgtagg aggtggctta
     8281 cttgaaagaa gtcgttatga tagatgctgc aagaacgccg ataggaaagt atcgcggaag
     8341 tttaagtcca tttactgcag ttgaattagg cacacttgtg actaaaggat tattagataa
     8401 aacaaaactg aaaaaagata aaatcgatca agtaatattt ggaaatgtcc tgcaagctgg
     8461 taatggtcaa aatgttgcca gacagattgc tttgaacagc ggtctccctg tagatgtccc
     8521 agcaatgacg atcaatgaag tttgcggatc tggtatgaaa gcagtgatct tagcacgcca
     8581 gctgatccaa ttaggtgaag cagaacttgt gatagccggc ggaacagaga gtatgtctca
     8641 agcacctatg ctgaaacagt atcagtcaga aacaaatgaa tatggtgaac caatttccag
     8701 tatggtcaac gacggattga ctgacgcatt ttcaaatgca catatgggat taaccgcaga
     8761 gaatgttgca acacaatttt ctgtgagcag agaagagcag gatcgctatg ccttgtcgtc
     8821 ccagttgaaa gcagcacatg ctgtcgaagc cggtgtattt tctgaggaga tcatcccagt
     8881 caagatttct gatgaagacg tgttatctga ggatgaagca gttcgtggaa atagtacatt
     8941 ggaaaaactg ggcacgttac gtacagtatt ctcagaagaa ggaactgtaa cagcaggaaa
     9001 tgcttccccg ttgaatgacg gtgcctctgt ggtgatcctt gcatccaaag aatacgcaga
     9061 aaataataat ctgccttatt tagcaaccat caaagaagta gcggaggtcg gtattgaccc
     9121 aagtatcatg ggaatcgctc caatcaaagc cattcaaaaa ttgacagata gatcaggaat
     9181 gaatttatca acaatcgatc tttttgagat caatgaagca tttgcagctt cttctatcgt
     9241 agttagccaa gaactgcagt tagatgaaga aaaggtcaat atatatggag gagcaatcgc
     9301 attaggccat ccaattggtg caagcggtgc acgtatcttg actacattag cttacggatt
     9361 gcttcgtgaa cagaagagat acggtattgc ttcattatgt attggtggag gtttaggctt
     9421 ggcagtcttg ttagaagcga atatggagca aacacataag gatgtgcaaa aaaaaaagtt
     9481 ttatcagctt acgccatctg aacggcgcag tcaattaata gaaaaaaatg tattgacaca
     9541 agaaactgcg ttgatttttc aggaacaaac actttctgaa gagctctccg atcacatgat
     9601 cgaaaaccaa gtgagtgaag tggaaatccc aatggggatc gcgcagaatt ttcaaatcaa
     9661 tggcaagaaa aaatggattc cgatggcaac agaggaacca tctgtcattg cagctgcaag
     9721 taatggtgca aaaatctgtg gaaatatctg cgcagaaaca cctcagcggc tgatgcgagg
     9781 gcaaatcgtt ctatcaggaa aatcggagta tcaagcagtg atcaatgcag ttaatcatcg
     9841 aaaagaagag ctgattcttt gtgcaaatga aagttatcct tcaatcgtga aacgcggggg
     9901 cggtgttcaa gatatctcta ctcgggaatt catggggagt ttccatgcat acttatctat
     9961 tgatttttta gtggatgtaa aagatgcaat gggcgctaac atgatcaact cgattcttga
    10021 gagtgtggca aacaagttac gggagtggtt ccctgaagaa gagattctat tcagtatttt
    10081 aagtaatttt gctacagaat cattggcttc tgcctgttgt gaaatcccat tcgaacgctt
    10141 agggagaaac aaagaaatcg gtgaacaaat tgccaaaaaa atccaacagg caggggaata
    10201 tgcgaagctt gacccttacc gtgcagcaac gcacaacaaa gggatcatga atggtataga
    10261 agctgtagtg gcagctacag gaaatgatac acgtgcggtt agcgcttcga tccacgccta
    10321 cgcggcaaga aatggattat accaaggatt aacagactgg cagatcaaag gggataaact
    10381 agttggaaaa ctaacggtgc ctttggctgt tgccacagta ggcggagctt ccaatatcct
    10441 gccaaaagca aaagcatctt tagctatgtt agatattgat tcagccaagg aactagcaca
    10501 agtaattgct gcagtagggt tagctcaaaa cctggctgct ttgcgtgcat tagttacaga
    10561 aggaatccaa aaaggccaca tgggacttca agctcgttca ttagcgatct caattggggc
    10621 tattggtgag gaaatcgagc aagttgcgaa aaaattacgt gaagcagaaa agatgaacca
    10681 gcagacagct atacaaatat tggaaaaaat ccgggaaaaa taaaaaagca atatctttag
    10741 aagaataaag caagatttac agttatttta tttactgcag atcttgcttt tttggctctt
    10801 cgtcaaattg tgttggcgaa gacaaatttg aataaaactt agtccgatat gcggcgcgtt
    10861 ctgtgcgccg catatttttt tagttttcaa agatcagacc ttgttgtaaa tagatccgtg
    10921 cccgaaagtt ataaaagttg cgataaccaa acgcaattcg tttaatcagc ttgatcttgt
    10981 tattcagccc ctcagtgacg ccgtttgagt ggggcacctt aaaggcattt gaaatacccg
    11041 attggtagcg atggaagatc gtgaatttct ttttaaacga ctgaggtaac gtagatgaaa
    11101 ttgttttaag ggtttcttga aagccttccg tatctcgttt aacgaaataa tagcgtaata
    11161 attgacaaaa atgatacgca gttcgcaatt cttcgttgta gcttaacagc tcatcaacga
    11221 tttctgtttg actaattggt cgtttaaaca gtcgatgata atgccgtttg agtggctcca
    11281 atgtcgtgga atctttgagt aagagtttcc aatatcgctt gagccgacgg tacttcttct
    11341 gattttcaga gtgtgaggtt cgaaaacgat tcatgatctg gacacgtaat tgattgaagc
    11401 tgcgattgat gtgttggaca atatgaaagc ggtcagttac gatctccgca tttggaaaga
    11461 ctgttttaag caactgacaa tagctggcat tcatgtccat cactaggtac ttgaccttta
    11521 aacgggcctt tctaggaaag cgcaggaagt attgagttag tttgtaaagt ctgcgatctt
    11581 caaggatcgt aaatagctga ttggttgtcc catcaacaca aataaaactc atggaaccag
    11641 aaacagactt cattgatttg aactcatcca tacacaacac cgtcggaagg aagttcatac
    11701 gtggctggta atgcttcgtt gcttcacgca agatccgtgt caccgtccca tccgagacga
    11761 agtacttctt agcgattagt ttacgtgatt gattttcgta cagttccatg agaatcgcct
    11821 gcttcagttc ctttgttagt tgatgatgtt catcaactaa gtccgttttc gcagaaaagg
    11881 tccgtccaca atcatggcag agaaaacggg tacgttttaa ttctaaaata gtcaactttt
    11941 ctttgacttt caacatctga gtgcgtgtcg tataggaacc gttgcggata atacgaatcg
    12001 atccacagtg ttcacaatgg gaaggtgagt catccaatct ccctttaata aactgcgctt
    12061 gaacgccttt atattctttt tcaatcagcc attcttcatc aaaaaataaa tgtttatctg
    12121 ttaatccgag taattttcta gtatgattat ccattgagag actcctttgg tagggtgacg
    12181 ttttggtcga ctaaatttta ccaaaagtga gtctcttttt gagttgaaac gaagaaaaaa
    12241 gtgttagtag aaaatcgctt tcgattttcc accaacacaa aatattatag aaccgctttt
    12301 ttctctatca gaaaatatgt ttattattag aattttttat agttaaggtt aggcatctta
    12361 agaaatcagg caactccaag atatcttcag gtagaagaga agtcgcctaa cattgtagga
    12421 tcataggtga tttgttggac aggtcaagct gatatttgag cctgatgtta gaaggaattt
    12481 ctttttactt gctgtagaaa ttattatatg actaaaaagg ctgggatttt aaatcccagc
    12541 cttttatgac aaatagaatt tttatcgatc agtaatcgct gtcgctgcaa attgttcgat
    12601 caaaggaatc aaagtcaatt tgactttgta tttccgttcg agtgcttttt cgataacgaa
    12661 ctcattttca gtagtcatag aaatagttgc taatttacga ggttcatcag catttttttc
    12721 attaataact acttcatgtt cattttgttc tgtgtaaaat ttaggatact cagcaacggc
    12781 ttttgaaaaa tcagcaaaac ttaaagcggc attcgtatca gttgagcgtg tattttcagt
    12841 tgtgtccgct tttggttttt ccgttttttc ttctggcaca ctgactgttt cttctgtaac
    12901 tggtgtcgca acagcttgcg cagttggttc atcgtttttc aatcgttgat cattccagta
    12961 agacacgatt tcaataagaa gattgtcacg gaatcgttcg aaaatcccgt tttctcctga
    13021 acgaattctc tttaatacag tattgaagtt gtcatcgatt ggcacgttga tccgtgtatc
    13081 ttcatttgtt ttcccagcta atccgatcgt taagatttga cggtttttgg gatcaagcat
    13141 gacttgtaac ggcaaaccat aacgtcgcaa gctctcttct tctagagaac ggaataattg
    13201 tcctcttaca ccatccaatg aaggacggaa ttgatttaat aatttttgtt tctgtttttt
    13261 cttcatatgt tctctccttc gctcataccc tttcgattat aagaaaaaaa cagccaaatg
    13321 aaaaggagta atgcaaaaaa acttgcgtat acgcaaatta caacagaaaa atttgcgtat
    13381 tttcccgttt tttgaaagaa aaataaaaaa tggaacggat tatgtatata tacataatcc
    13441 gttccattct ttctattttt tcggtatcaa ggcaaaaaca ggtagttcag gtgaataaat
    13501 gacttcatgt tcgtgccagg gtttgaccat tagcgaatga tcgaaccgtt ttttcagttc
    13561 ttcgatgatt tgatcatgtg tccagtttct tgcaggaaaa tgttggattt tctctgcatc
    13621 gatcaaaaag acaaaatcgg aatgaaaagt ctgggtaact tcttccgaga gagaattcaa
    13681 gcgttcgatt ggatccataa aatcaccttt cgacttaaaa ttgggtagta tctgggtctt
    13741 ttgctttgcc gactacacca tctaactgat cgatttgttt catttcttct tctgttaatt
    13801 caaaatcaaa taattcagta ttttctttga ttctgcttgg tgtcactgac ttaggaagag
    13861 gaaggaattc gtgttgcagc gaccaacgca aagcaacttg tgcaatcgtc ttgtcatgtg
    13921 cttcagcgat ttgtttcatt tcaggcacat cgaagatttt accagtgcct aatggactat
    13981 atgcttcgag gatcatatca tgtttttttg catactcaac tacagttgtc tgtaattcgc
    14041 ctggtgcaag gaaaacttga ttgaccatcg gcataatttt tgctgttttt gctagtgtat
    14101 ctagatggtg gggtaagaaa ttgctcacac cgattgcttt gattttacct gcttcataca
    14161 gttcttcaaa tgctcgccat gtatctgcat ttgcttgttc ccaattatca cgaaaagcaa
    14221 cagggtttgg ccagtggatc aaaaacagat ctaaataatc tgtttggagc ttcttcaatg
    14281 attcttcaaa agaagacatc acaagttcat agctgtggtt tgcattccat aattttgttg
    14341 tcaagaatat ctcttctcta ggaattccac tttccttaat cgcttggccg acgctttctt
    14401 cattcttgta tccttgggca gtatcgatat ggcgataacc tgcagccagc gcttctttaa
    14461 cagaggaaac agcgacatcc ccatcaggtg tttgccatgt gccgaatcct actaccggga
    14521 tttcgtaacc atttgataga cgataagtgc ttgttaatga attcatactt tcagctcctt
    14581 ttttattcgt tcaactataa gtgtagcgca tttttcgaaa aaaagaatcc attttgtttc
    14641 tactcttgaa atttttgttt aaaagaaaat gattttgatt ctggtatttt tgattttttt
    14701 tccgtaaact aagacagaag ggaatgagaa aatggatatc tatttaaaaa aagcaattct
    14761 gcatattatt gacagagaaa ctggttctcc agtcttttca caaaaagagc tggatctgac
    14821 aaaagaatat attcgtgatt ttcttcaaaa gaagatccaa aaaatctctt ctgctcaaac
    14881 aaaaactgga caactagcag aagaaagcat gatcgttgaa tcacttaaaa tcgctcaaga
    14941 aaattttgtg gaagcaagtg aagcaatcgt tcagcggtgg ttcgatatct accaagaaag
    15001 tgaagaagca cctagtgcag atgtatttgt tgtcttgtat gaattagata cagtgatgta
    15061 cttatcttta ttgaaagtca attatcgtga ggcttacact cactttgttg aagcagacga
    15121 agcagggatc gacaaccgct tgattttgaa tcgagcaatt ctaggggcga aaacacaaaa
    15181 agcagatgaa gcattcgctg tgaatttgac tgattggacc tacgaattaa ttgaaaaaaa
    15241 atatgagttt tctggcaaaa aagagcttta tttttctgga agagtgatcg aaagtgttcc
    15301 tgcaccttct ttagaagaaa atgtaaaagt gatccaaaaa gtagccaagc atcttggaaa
    15361 aaaatttgag acagaagaat ttgatatcat ggctgatttg aaagaagctg tctatgatac
    15421 gatagaagaa aaaggtcggt tggatcatga gatgattgcg gaaaaagtct tcaaggaaaa
    15481 catcacggca aaaatggctt ttaaagaaga agtacaagag caaggatttg tcccagaagc
    15541 acctcctgta aaagaagtac aagaaatttc tgagaaaaaa tttggaaaac aaaaattcaa
    15601 gctatcaaac gggatcgaac tgatcgtacc agtagatgta tatcgcaacc cagatttgat
    15661 tgaatttgtg aataatccgg atggtacgat atccgtgatg atcaaaaatg tggatgaagt
    15721 attgaatcgt ttataaaaat gactagaata ttaggtgttc aagtaccagt gatcagttaa
    15781 atgaattgtg tcaagagaag gatcggaaaa gacgaatata acaaaaaaag agcgtgagac
    15841 aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg aagcagaagc
    15901 a
//
LOCUS       DAZKCH010000061        15742 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000061 DAZKCH010000000
VERSION     DAZKCH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.061"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(24..722)
                     /locus_tag="ACG84X_002021"
     CDS             complement(24..722)
                     /locus_tag="ACG84X_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFP9127867.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="ACG84X_002022"
     CDS             complement(715..2067)
                     /locus_tag="ACG84X_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFP9127868.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="ACG84X_002023"
     CDS             complement(2290..3690)
                     /locus_tag="ACG84X_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFP9127869.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="ACG84X_002024"
     CDS             3851..4588
                     /locus_tag="ACG84X_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFP9127870.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="ACG84X_002025"
     CDS             4713..5192
                     /locus_tag="ACG84X_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFP9127871.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="ACG84X_002026"
     CDS             5189..5956
                     /locus_tag="ACG84X_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFP9127872.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="ACG84X_002027"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="ACG84X_002027"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFP9127873.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="ACG84X_002028"
     CDS             complement(6859..7461)
                     /locus_tag="ACG84X_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFP9127874.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..7797
                     /locus_tag="ACG84X_002029"
     CDS             7567..7797
                     /locus_tag="ACG84X_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127875.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            7788..8036
                     /locus_tag="ACG84X_002030"
     CDS             7788..8036
                     /locus_tag="ACG84X_002030"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9127876.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            8142..8726
                     /locus_tag="ACG84X_002031"
     CDS             8142..8726
                     /locus_tag="ACG84X_002031"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFP9127877.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="ACG84X_002032"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="ACG84X_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFP9127878.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="ACG84X_002033"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="ACG84X_002033"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFP9127879.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="ACG84X_002034"
     CDS             10627..10806
                     /locus_tag="ACG84X_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127880.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="ACG84X_002035"
     CDS             10828..11853
                     /locus_tag="ACG84X_002035"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFP9127881.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12028..13272
                     /gene="glyA"
                     /locus_tag="ACG84X_002036"
     CDS             12028..13272
                     /gene="glyA"
                     /locus_tag="ACG84X_002036"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFP9127882.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13425..14372
                     /locus_tag="ACG84X_002037"
     CDS             13425..14372
                     /locus_tag="ACG84X_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFP9127883.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14506..15135
                     /gene="upp"
                     /locus_tag="ACG84X_002038"
     CDS             14506..15135
                     /gene="upp"
                     /locus_tag="ACG84X_002038"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFP9127884.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15274..15516)
                     /locus_tag="ACG84X_002039"
     CDS             complement(15274..15516)
                     /locus_tag="ACG84X_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127885.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15637..15709
                     /locus_tag="ACG84X_002040"
     tRNA            15637..15709
                     /locus_tag="ACG84X_002040"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15670..15672,aa:Thr,seq:cgt)
BASE COUNT         5349 a         2823 c         3195 g         4375 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaaaggagct gttgtttgtg gtagattaca aaacgtttga ccctgatctt
    12061 tgggctgcga tcgccaaaga agaagaaaga caagaacata atttggagct gattgcctct
    12121 gaaaactttg tctccgaagc agtgatggct gcacaaggaa gtatcttgac aaataaatac
    12181 gcagaaggtt atccagggca tcgctattat ggtgggtgtg aatttgtcga tatcgttgaa
    12241 aatttagcga ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa cgtccagcct
    12301 cactccggct ctcaagccaa cacggctgct tatctcgctt tggtagaacc aggggacacg
    12361 atcttaggaa tggatctttc cgcaggcgga catctaacac atggatcacc agtcaacttc
    12421 agtggcaaaa cctatcactt tgttgcttac ggtgttgatc cgacaacaga agttattgat
    12481 tataatgtgg tacgtatttt agctagaaaa catcaaccaa aattgatcgt agcaggtgcc
    12541 agtgcttacg gacgaacgat cgactttgcg aaattcagag aaatcgcaga tgaagtaggc
    12601 gcaaaactga tggtagatat ggcacatatc gcaggattag tagcagcagg acttcatcct
    12661 aatccagttc cttatgcaga tatcacaacg actaccactc ataaaacatt gcgtggccct
    12721 cgaggcggca tgattttgac aaacgatgaa gcattagcaa aaaaaataaa tagtgcggta
    12781 tttcctggta ttcaaggcgg ccctctagag catgtgattg cgggtaaagc agtagcattc
    12841 aaagaagcat tagatcctgc atttaaagaa tatagtgaac aaatcatcgc caatgcaaaa
    12901 gcaatggtca aagttttcaa tcaagcaatt ggaaccagag tcatttcagg ggcgacagat
    12961 aatcatctga tgttgatcga tgttcgcgag ttaggtataa atggaaaaga agcagagagc
    13021 attttggaca gtgtgaatat cactgtaaat aaaaactcga ttccttttga aacactaagt
    13081 ccattcaaaa caagcggtat tcgaatcggc acgccagcaa tcactactcg cgggttcaaa
    13141 gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc aaaagatgat
    13201 aacgctcaac tagacgaagt caaaacaggt gtacgcgaat taactgaaaa atttccgttg
    13261 cataaaaaat aaaaatttaa attccattag taaacagaaa agttcaatgt tgggcttttc
    13321 tgtttatttt ttgggaaaac ggattctttg acaatatcgg tgatgctctc tagtatatga
    13381 ggtgtaattt tagtcttcac actaaatctc agggaggaaa agtcatgact gatcgtatct
    13441 cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc gcctcatccg cgtatctatg
    13501 aactagcacc ggaagaagga agagttttac tagaagaagt acaagaatca cctgtgaaca
    13561 aatattccgt cgatattgaa gacttgatgg tggatactgg cgaatgggga aaactcaata
    13621 ttcgtctcgt acgaccagaa gggaatatgg ataaattacc agttattttt tatattcatg
    13681 gagcaggctg ggtttttggc agtgctcaaa cccatgataa attgatcaga gaacttgcgg
    13741 ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg atcaccagaa gcaaaatatc
    13801 caacagcaat tgaacaaaat tatgctgtgt tgcaacagct gaataaatta gccaagtcaa
    13861 aaaatctgga tctcgagaat ctaatcgttg caggagattc agtaggtggt aacatggcta
    13921 cagtcatgac gatcttaaca aaagaacgaa agggcctccc aatatccaag caattgctgt
    13981 attatccagt cacaaacgct gattttgata cagattccta tcatgaattc ggagaaaact
    14041 attttttgac aagagaagga atgatgtggt tttgggacca atatacgacg aatgaagaag
    14101 agcgtgctga aatcacagct tcgcctttga gagcaaatat aaatgaacta aatgatcttc
    14161 cttcagcaat gattttaacg ggagaagcgg atgtattaag agatgaaggt gaggcttatg
    14221 cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt acgcttccaa ggaatcatcc
    14281 atgattttgt catggtaaat gctatggatc agacaaaggc aacgcgtgca gcaatggcat
    14341 tatctacttc ttggatcaag aaaaaagaat aagctttgct tgtccgcagg aaaacttctt
    14401 ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac tagtcaatca cttgattttg
    14461 ttttacaatt aaaaagaaac gacagaacaa aggagagctt aaaaaatggg caaatttcaa
    14521 gtgatcgatc atccattgat tcaacacaaa ctaactatta ttcgggacaa aaactgcgga
    14581 acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata tgaagtatca
    14641 cgggatatgc cattggaaga catcgtgatc gaaacaccga tcactgaaac aacacaaaaa
    14701 acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat tggaatggtt
    14761 gacggtatct tggaattgat tccagctgct aaagtgggac atatcggtct ttatcgagat
    14821 gaagaaacat tggaaccaca tgaatatttc gtcaaacttc cagaagacat tgatgcacgt
    14881 cagttgtttg tagtagatcc aatgttggca acaggcggat cagcaatcat ggcaatcgat
    14941 gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc agcacctgag
    15001 ggagtaaaag ctttgcaaga agcgcatcct gatattgaca tctatacagc ttctctagat
    15061 gaaaaattga atgaacatgg ttatatcgtt cctggactag gggatgcggg tgaccgtttg
    15121 tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc acatcctttt
    15181 ttggtcattt ttaacgtttg atgcagaaca gctttttcac agctttcgtt tgcatataaa
    15241 aaaaccatcc caaaaatgca gagatggtca aattcaaatc ttttttagtt ctttgtagtt
    15301 aacgattact acacccttac tttgcgtcat caagttcgca ttttctgcag tttcatcaat
    15361 ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg acttgccgtg
    15421 aattgtgaac attacgtgag tattgatctt gaatttttca ccaatttccg atggtacgat
    15481 agttgtatca aattttccaa aagttgccat tttcataaaa cctgcctttc acatcaatta
    15541 taccacgttt tatgaaaaat atcatgaaat taaactaatt ttccatcgga ctctttacaa
    15601 tcagccaaat agagtatata atttcttttg gataaggcca gcttagctca gttggtagag
    15661 caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat taaaagagaa
    15721 gacagatata tcaaggattt tt
//
LOCUS       DAZKCH010000062        15640 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000062 DAZKCH010000000
VERSION     DAZKCH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.062"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(133..2478)
                     /locus_tag="ACG84X_002041"
     CDS             complement(133..2478)
                     /locus_tag="ACG84X_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFP9127886.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKNEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            2757..3659
                     /locus_tag="ACG84X_002042"
     CDS             2757..3659
                     /locus_tag="ACG84X_002042"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFP9127887.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            3870..5645
                     /locus_tag="ACG84X_002043"
     CDS             3870..5645
                     /locus_tag="ACG84X_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFP9127888.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(5711..7297)
                     /locus_tag="ACG84X_002044"
     CDS             complement(5711..7297)
                     /locus_tag="ACG84X_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFP9127889.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            7548..7772
                     /locus_tag="ACG84X_002045"
     CDS             7548..7772
                     /locus_tag="ACG84X_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFP9127890.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            7914..9665
                     /locus_tag="ACG84X_002046"
     CDS             7914..9665
                     /locus_tag="ACG84X_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFP9127891.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLERELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            9665..11449
                     /locus_tag="ACG84X_002047"
     CDS             9665..11449
                     /locus_tag="ACG84X_002047"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127892.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQEFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            11784..12636
                     /gene="licT"
                     /locus_tag="ACG84X_002048"
                     /pseudo
     CDS             11784..12636
                     /gene="licT"
                     /locus_tag="ACG84X_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
     gene            12733..14619
                     /locus_tag="ACG84X_002049"
     CDS             12733..14619
                     /locus_tag="ACG84X_002049"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFP9127893.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAADGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMSLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVINYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(14660..15562)
                     /locus_tag="ACG84X_002050"
     CDS             complement(14660..15562)
                     /locus_tag="ACG84X_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9127894.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
BASE COUNT         4802 a         2859 c         3238 g         4741 t
ORIGIN      
        1 ggtttttcac atttttacat aaatttgtct taatatcgta gatgtaagct tttgaacacc
       61 atttattcgg aaaaagggag ctgtgacaag atttttgtcg cagctccctt taattctgat
      121 taatctatta gatcaatcat ctttatcgtc tgattctttg gtctctggat tcgctctagc
      181 ataagctgaa gcggtgttcc agtaatctgt atagttttca tcagtaccgc ctacgccgaa
      241 tttaaaggcg cttttcttcg gaccattttt tgcccaaagt gactccactg tttttcctgg
      301 cgtttggatg gattttttat tgacagtaac ttttccagct gtttgtcctg tgaacccaga
      361 tacttttttc ttcatcacat cggatgataa gtcaaatttc tcatcagtgc cgaaaatctc
      421 agggtttgct tggtaagctt gattgattag attggcaaga taattagccg aacgtattct
      481 tgcttggctg tccattccag tattgtcatc gtgtcctgcc caactactga tagtgataga
      541 tggagttgag acgatcagcc atgaatctcg gtattcattg gtagaaccag tttttccgac
      601 ccaatctgca tttcctagat ttccgtttaa gcttgagatg acatctttga atggtgtagt
      661 gattttttca ttgatcacac tacgcatcat gtcattcatg atcgatgccg ttgcttcgga
      721 ataaatacgg acagaattac tttcatgttt ataaatcaca ttacctgcat tatctgtgat
      781 ggaatcaatg atatagcctt cttcgtagac tccaccattt gctaaggcct ggaatccatt
      841 tgtctgttga agcgtcgtta catctactgt ccctaaagga gccgattcaa cgccccaatt
      901 atcatttgct gggtagttca tcttcgccaa gtagtgctcg taagcgtatt gtttcgatcc
      961 accggaattc aacacatctt gatataagtg ataagctggg atattgttgg accattccag
     1021 tgactcacgg acggtttgga aggtgttcga cccttcattg gtcgcattga cgattttctc
     1081 accagcattt tttccttctt gccaagtcgt tgcataatct gatacacggg attctgatcc
     1141 gacaagtccc atatcgattg caggaccgta aacaagaacc ggtttgatgg atgaaccagc
     1201 ttgacgttct gtatcaaagg cgtggttatt ttgattctgg ctgtaattcc gaccacccac
     1261 gaagccatag atacgtccgg ttctgttatc catcaataca tttccagtct ccacttggct
     1321 accagcacca tcatctaaca tgtagccata attttctacg ccggtttgta atgcagcata
     1381 gatatcttta tcgatcgtcg aatggatcgt atatcctttg ttttggatcg tttgctgtgc
     1441 tttttgataa taagcttcac tgaccgatga atctgacata tcagcattat ctttttctgc
     1501 caattgttgt gcaataatcc ttgttgcttc gttcatcacg gtataataca agaattctct
     1561 gtcagtctgt tccgcgattt gttgtgggag aaagtctttt gtaagatcat aggctttcgc
     1621 ttcttcgtat tgttctttcg taatttgtcc ttcacggtac atactgaata aaacaaaatc
     1681 ttttctggca agaccggcag aaagatcttc ttttagcgcg cctgtattcg tgtatggact
     1741 atacgtgata gggctttgag gcaaaccagc gatataagca gcttgtggca gagtcacatc
     1801 ctttgcatct acaccaaaga ttcctctagc agcttcctgg actccagcaa tattttgccc
     1861 cttattattc cgaccaaatg gtgagacatt caaatacgta gtaatgatct cattttttga
     1921 aaagtgtttt tctacttgtg cagaaagaac gatctcgttt gctttacgtt tgaatgttgt
     1981 ttcatcggtt aggatctgtt gtttgactaa ttgctgtgtc aaagtggatc ctccagacga
     2041 gccgatgcca gtcgcttctg aaactagtgc tcgtaaaaca gctttaggga cataaccttg
     2101 atgtttatcg aagtattcat cttctgtact gataatcgcg gttttcaata aaggcgaaat
     2161 cttatcagat gaaatagtcg tccgcatcag atctgtctgg atttttgata tctctgtatt
     2221 atctgcataa acaatctttg acgtttccgt aatgtttcct agttctgtct gcagttcttt
     2281 tttagtcggc aattgtgtgt cttcgacaag ataggcaaag tagccagcac ctattccgat
     2341 acctagagct gcgaacaaca aaagaagaac agtaataaaa acagtcaatg attgaaacac
     2401 tctaaaaata atcttaggaa caaaccattt ttcttttttt cttctattct gtttttttcg
     2461 agtatttttg cgtggcaaaa gggtcacctc aactaatggt tttatttcgc taattatagc
     2521 aaataatagg acaaaaaaac agacaaggct gtttttgaca ggaatttctt tttcgaatga
     2581 gataaaacgt gaggaaatga tcttttttat gaaagagttc ttaagctttt ctttagggaa
     2641 agtttcagtt actatggaga acagggcaaa gaaaaacaaa ccattttctt tgtacatcat
     2701 cttatcaata tacaggaatt gttcgaaaca attgcctttc aaggaggaat ccatccatgt
     2761 tattaggctc acatgtcagc atgagcggaa agaaaatgct gttaggcgcg gcagaagaag
     2821 cagccagtta cggatcttcg acctttatga tctatacagg cgctcctcaa aatactagaa
     2881 gaaaagctat cgaagagatg aatattgatg ccggaaaagc atttatggca gaaaacggac
     2941 taacaaatat cgtcgttcat gcgccttata tcattaattt gggaaatacg atcaaaccag
     3001 aaatgtttcc atttgctgta caatttctga gagaagagat tgtccgtgcg gaagctttag
     3061 gtgctactca aatcaccctt cacccaggcg ctcatgtagg agcaggggca gaagctggga
     3121 ttgctagaat tattgagggg ttgaatgaag ttttgacaaa agaacagacg gcacagatcg
     3181 ctttggagac gatggcaggg aaaggtacgg aaatcggtcg aacatttgag gaattagcgc
     3241 aaatcatcga tggagtaaaa ttgaatgaaa aattatccgt tacttttgat acatgtcata
     3301 cgaatgatgc cggatataat ataaaagaag atttttcagg tgtaatggaa gagtttgata
     3361 aggtcatcgg attagatcgg cttaaagtac tgcatatcaa tgattctaaa aatccacaag
     3421 gttctcataa agatcggcat gccaatatcg gttttggaac aattggattt gacacattga
     3481 acaaaatcgt ccatgatcca atgtttgaca acatttcgaa aatattagaa accccatatg
     3541 tcggtaaaga taaaaagaaa gcttacgcac catatggaaa agaaatttcc atgttcaaag
     3601 cgcaagcatt cgatcccgaa gtgttccctg agttattagc agaagaagtc acactttaag
     3661 ttttctacct gacagcaaca aaaaaggatt gggcagtctg ccttgtcctt ttttgtttaa
     3721 gaaacaaagg agtgcttttt gcattcgttt tcgccatgct ccttttgccc cctcttttta
     3781 aattcagaca aacagggtat actgatagaa aagtaaaaaa cgaaaagttt cacaaacaag
     3841 tagcaaaacg tgattgaaag gacgaaaaga tgctgaacat tttaaacccc ttgatcgacc
     3901 aactaaaaaa gaaacataca tactttattc ttggcatagc cgtattattt acaattattc
     3961 ggttgtattt atatagtaaa gcaatctatg gaacagatat gtcggcgacc tatgatgatc
     4021 agctgctgat tcactatgct caaaatattt tggatggtaa atggctaggg gagtatacga
     4081 ctacaacact ttccaaagga atctcctaca gcttattttt agtacttgca cataaactgc
     4141 atctttctta tgcagttttg ttcggcatgt tcagtatttt tgccagtata ttggttgcac
     4201 tcgcgtttaa accgattgtg aagaacaagt atcttctttt aagtatctat ttttattttt
     4261 tgttttctcc gattagtttt acacatgaat attccactcg aacatatcgt aatgccctcg
     4321 tgattccggc tgttgagatc attatcgctt gtttattagc tatttattac cgcaaatacg
     4381 gttctagcag aaaattgctg ccatggtttt tagggctttc tgtcgctttt cctttctttt
     4441 ggttcattcg cgaagattct atctggcttc ttccttttac tgtagtagct ttgggtatca
     4501 gtttcgtcca gatcttgcta gggcaagact tttctttcaa agaagtaaag aagttaaaaa
     4561 aacgactctt tcttctctcg aaacgggaat ggctgaaact ttcattgttt ttacttccta
     4621 tagttggctt ttccatcgtc tatcagtgga tcgaatataa aaatgagaca acatacggta
     4681 ttgcaaccat caatgaccgt tccagtggag aatttggacg tttgatgaaa caactgatcc
     4741 gaatagatga tgaaacgaac ttgaataaag aaaacagtga gatatgggtc tcacatgctg
     4801 cactaaataa agcattagcc gcatctccta cattccatac tgtttctacc cgtattgacg
     4861 aattatatac gactcacgcg tggactcaag gtggaaaagt aaaagaatta cccggagata
     4921 tcatcttttg ggcattgcga gatgtggtaa gcgaatctgg ttattaccaa aacaatgcaa
     4981 aagaaaccaa tgatttttgg aaaaaagtca accaagaatt agaagaagcc tatcacaagg
     5041 gaaccatcaa aaagaaaaaa gagttctatc tgatgggatc aggagatgga aagacgatga
     5101 gtgatctgcc aatcgtattc gatttccttc aatcaggata cgcttatgca tggcgatata
     5161 aagatttcca tcaaggagga aattatagtt tcggaacgca agaacaagtc aaacaggctc
     5221 aagaattatt aaaccttccg ctaatggaga attggatcga tagtaatgaa ccgagaacac
     5281 ctaatttcca attaacaaaa tcagcaaaag tcgcgaatgt catcataaaa atttaccaag
     5341 ttctggctat tcccgtgctg attgcttcaa tagcagggat attacttatg atactaggaa
     5401 ccgtatttgc aaaagctgat cgtgcctatt atagttcctc tttgattgtg gtcaccggat
     5461 taatactgac acaattggtt tttcttttcg gtgtctcatg gttttgttct tatgcgccag
     5521 aaaaaaagga ctatttttta agtgtctaca ctggtgcagg cgtgccatta acgcaattca
     5581 tcgtagtaac aagcatgcta gttttcagta aattaaatct gaaaaaagct ttatcttcta
     5641 aataaaaaga cccttggtag ctagattttt aacctaacta tcaagggtct ttgtgtggaa
     5701 aaatcagttt ttattcgatt tcttctaccg tttcctgcaa aagctgttca tattttttgt
     5761 ttcctttata taaatcacca atcgtccatg ccaacaggag aaggacaaga acaatgatta
     5821 cataagcgat gtgatcagcc aatgctagtt gagcggaagt ggcttgctcg ccgaagaaac
     5881 tttcgatctg tcctggtaat cctcgtaagt tcaagtaagt tagactaatc acagagaacc
     5941 agccaagaag ttttacgatg aatgaatttt taaatcggct acccatctcc gcttggctgt
     6001 tggtcatcat cagtaaagga atcatcgaaa atggcaacgc aaaagccaag aacacctggg
     6061 attcattcat taagttattc aaagcggcat gttcttcgat cgttcctttt gtacttgtaa
     6121 acaaaacaca aatcaataca ggaatcacag aaagcaatcg tgtgaccagt cttcttagcc
     6181 aaatcgggat acgcatatgg atgaatcctt ccatgatgac ttgaccggtc aacgtaccag
     6241 taatagtaga gttctggcca gaagcaagaa gtgctacagc aaataaagtg gacaagatac
     6301 cagattttgc tacagcaatc aaaataccat tgctcatagc tgatggatca gataaagctt
     6361 catacagacc aaaaaaggaa ggatcttgga cagaaccggt tttgaagaca gcgacaccca
     6421 tgatcaatag cagtgcattg actagaaaag ccattgacaa ctggatatta gaatcccaag
     6481 tagaaaaacg tacagcttgt gctacatctt cttcgttttg gtgatcgatc ttccgagttt
     6541 gtgaaactgc tgaatgaaga tataagttat gcggcatgac tgttgcacca ataatcccta
     6601 aagctccagt cagcggagtt tcgccgccga tgaccggtga gtctgagaat gtatgactgt
     6661 tagggataaa gccagcaaat aaactgtgcc aatctgggtt agacaagcca acttgataga
     6721 caaaaacgaa taaaatgacg aaaattaagc agacaaccag tgcttcgatc ttacgaaacc
     6781 cgacttttgt cagtagtaag agaacgaaaa catctaatac agtaataaag acggcaatca
     6841 ccaatggaat atcaaaaagt aagtagaggg cgattgctgc accaatgact tctgcgatgt
     6901 ctgttgccat aatggctaat tcagtcaaga tccataaaat gacacccaat gtcttacttg
     6961 tccgtgctcg gattgcttgg gccaaatcca tttgggtcac gattcctaat tttgctgcca
     7021 tatactgtaa aagcatagca attagactag acatcaaaat aactgacatc aataaatatt
     7081 ggaaattttg tccaccagtg atcgaagtgg accagttacc tggatccata taaccaactg
     7141 ctactaatgc acctggtcca gagtaagcaa gaagtgtttt aaaaaaactt tttccctttg
     7201 gtacatccac tgttccattt acttcagcta aagataaacc atttgtatgt tcaataagtc
     7261 gatgcttatg aaattgtttg ttggattgat tattcaagaa aaaaccacct ttcctattta
     7321 tctacgatta cattctacac ctcagaaaga aaaaattaaa gaaaaagatt cggtatgcct
     7381 aatttttttt cgtggtgtgt cttgctggtt aatgaaagaa attttgttct tctctaaaaa
     7441 aaccactatt ttttgcatga aactaaagaa tacgcctttc ttttttcaat aaactttagt
     7501 aaaataaatc attgagagca attcggaaat agaaaggaga gatttatatg gtatcaacag
     7561 gtattgtcgt acttattgct attattgctt tgctaatcgg cgcagtaggt ggctttttcc
     7621 tagcgcgtaa atatatgaaa gactatttag aaaaaaatcc tcccgttaat gaggacatgt
     7681 tgcgatcaat gatgatgtca atggggcaaa aaccatctga gaagaaaatt cgccagatga
     7741 tgcagcaaat gaagaaccaa gggaaaaaat aggttctgac ccaaagactt tttgcgggct
     7801 gattttttca gtccgttttt tatttcgtaa tttgttagac tattcagact attcagcaaa
     7861 aaagacaagc acagacaatc ctatgctctt gataaagaca aaggaggagt aaaatgtcga
     7921 tttttagaaa attaggttgg ttttttcgtc aggaaaagaa acattattta attgggattt
     7981 tctccctatt cgcagtggcc ttggtacagt tagttcctcc aaaagtgatt gggatcatca
     8041 ttgatgagat cgccgataag aatttatcaa taaagatcat ttcctggtgg atcttattat
     8101 tgatccttgc agctttctta caatatcttt ttcgttatat ctggcggacg aatatttggg
     8161 gaagtgcagc tcggttggag agagaacttc ggcagcagct attcaaacat tttacagaaa
     8221 tggacaatct cttttaccaa aaatatcgga ctggagattt gatggctcat gcaacgaatg
     8281 atttgaatgc aatccagaat gtagcaggag ctggaatctt gacctttgca gattcagtga
     8341 ttacgggcgg aacaacgatc attgcgatga ttttgtttat tgattggcgc ttaacactga
     8401 ttgcgctgat tcctctgcct ttgctagccg ttacttcacg agtgctgggg tcaaaactcc
     8461 acgatgcttt tcgtgattcg caagaagctt tttctagtat caatgataag acacaagaaa
     8521 gtatcactgg gatcaaagtc attaaaacat ttggacaaga aaaagaagat ctcgcggatt
     8581 ttgaagaaaa gattgaagat gcaattatta aaaacaaacg agtcaatttt ttagactcct
     8641 tatttgatcc attcattacc ttgattatcg gtctgtctta tgttgcaaca attattttag
     8701 gtggaaagta tgtcttggaa ggcacgatct caatcgggca gatggtctca tttattagct
     8761 atatcggtat gcttgtttgg ccgatgtttg cgattggtcg attgttcaac gtattggaaa
     8821 gaggaaatgc ttcttatgat cgcgtcaatg aacttttgca tgaaaagacg catatcgtgg
     8881 aacaactggg tgcagtgcag accccggcaa aaggcgagct gaatgtagct atttcctctt
     8941 ttaactatcc gaaagaagaa tcaccagcat tagaacaaat caaatttgcg atccaagaag
     9001 gagaaacatt aggtattgtt gggaaaactg gtgcgggaaa aacgacaatc atcaaattac
     9061 tgatgcgtga atacgatgat tatcaaggga aaatccaatt tggcggacgt tcgatcaaag
     9121 aatattcatt gaatgcttta ttaggatcaa tcggttatgt gcctcaggat cacttcctgt
     9181 tttcgatgac cattcgagat aatatccgtt tttctaatcc aaaactttca gaagaagaag
     9241 tagagcatgc ggcttcttta gcatttatca acaatgaaat caaggaattg ccaaaaggtt
     9301 atgatacctt agttggagaa cgtggagtct ctttatctgg cggacagaaa cagaggattt
     9361 cgattgctcg agcattgatc aaaaatcctg aattgctgat cttagatgat gcactttctg
     9421 cagtagatgc caaaacagaa gaagctatct tgcataattt aaaagaaata agaaaagaga
     9481 aaacaaccat cattgcagct caccgtttaa gcagcgtgat gcatgcaaaa gaaatcattg
     9541 ttgtcgatca agggaaaatc attgaacgag gaacccacca cgagctgctt gcattaggtg
     9601 gctggtatga acgaatgtgg gaaaaacagc aattagaagc gaagatagaa ggaggcgagg
     9661 cctgatggat gaaaattatc aatcggaatg gacaaaatcg attccactta aagaacagaa
     9721 gaagatcatc aaacgactga tgaagttcgc caaacctttt agaagaacgt tcatcgttgc
     9781 tatcttattt gcgtttgccc tgtctgtgat caatgtccta ttgccaagga tcatccaaac
     9841 ttttatggat gatcatctgg ctaaacagtc agctacgaca caagttattt tgttttttgc
     9901 tggtgtgtac ttgtttggag tcatagtcaa aagtatcatt tggtttttcc aatggtattt
     9961 gtattccatg gcttcattga agacctatca gtatgttcgg gtaagattat ttgaaaagct
    10021 gcatacacta ggtatgcgtt attttgacca gacaccggca ggatcgaccg tttctcgagt
    10081 gacgaatgac acagaaacgc tatttgaatt ttggtatgtc tttttgatgg tattgactgg
    10141 gatctttgca gtcgtttctt ctttcgttgc catgtttcaa atcaatggag aaattgcctt
    10201 gtggactttg gtgttcttgc cgattttagg aatcgtcatc tggtattacc agaaattcag
    10261 ttctcgtatt taccgaaata tgcgggaaaa attaagtcag ctgaacacga aattgaatga
    10321 atcgatttcc ggcatgcgta ttatccagca gtttcgccaa gaagctcgtt tagctaaaga
    10381 atttgaacaa gtgaacaacg agtatttaga cacgcgctat gcgatgatca aaacgaattc
    10441 gattctgtta agtccaatca tcaattttct ctatgcattg gcgattgcgt tggcgttgac
    10501 tttgtttggg atcgatgcgt tgcattctcc cgtagaagtt ggactgatct atgcatttac
    10561 gacctatgtc caggaatttt ttaatccaat gtctcaaatg atggactttt tgagcacctt
    10621 tacagatggg atggttgccg gtagtcgtat tttgaaaatc atggatacag aagaatatgc
    10681 accgcaacaa aatcctggag cagatcaagc gattacttca ggtaagatcg agtttcgcaa
    10741 tgtaagcttt tcttatgatg gagagcacaa tgtattgaac aatatctctt ttgtcgctaa
    10801 tccgggtgag accgttgcat tagtggggca caccggaagc ggaaaaagct cgatcatcaa
    10861 cgtattgatg cggttttacg aattttatga aggccaaatc ttgattgatg atcatgacat
    10921 tcgagaatat ccaatggaag agttacgtaa gaaaatggga ttggtcttgc aagatgcctt
    10981 cttgttttat ggagatattg caggaaatat ccggatgatg aatccagcta tcacagacga
    11041 acagattcgc catgcagctg agtttgttca agcaaacaag ttcatcgatg aattaccaaa
    11101 aggatatcac tcaaaagtga tcgaacacgg tgccagctat tctagtggac aacgacagct
    11161 gatcactttt gcgcgaacaa tcgtgacaga tcctaaaata ctagtattgg atgaagcaac
    11221 agcaaatatc gatactgaaa ccgaaggatt gatccaagaa ggattggcaa aaatgcgaca
    11281 aggacggaca acgatagcga ttgcccatcg gctgtccacg attcgggatg cagaattgat
    11341 tttagtttta gacaaaggtc atatagtaga gcgtgggaat catgaaacac ttctagcgca
    11401 aaatggtttg tatgcagata tgtacaaact gcaaagcagt ggtgtgtaaa aagaggttgt
    11461 gacagtagca tagtagcatt ttgccctaag cgctagagtg aaaataaaac agagcttcgc
    11521 agattcttca tctgtgagcg ttagtggcgt agtcacccga tttaaaaaag acgacgacag
    11581 ctagtcaaaa gcggctaata accactaaga aagcgttgac aaaagcgttt gctttcgata
    11641 atataaagaa aacgatacaa cttggatagt gattgcctga tgcaagctaa acctgatgag
    11701 tctcccatgg ttccatggac ggctttttgg gtttttcttt ttgttttgga tacagcccta
    11761 tatatcatgg aaaggagcaa aacatgctga ttgagaaagt actgaataac aacgtcgtaa
    11821 taaccaggga tgaaagaaat caggaaatga tcgtgatggg aaaaggtttg gcattcaaaa
    11881 agaaagtggg tgacccgatt tttgactcat gcatcgacaa aaaatttcag ttgacaaatg
    11941 acgggctttc acaacagttc caagaattgg cacaagcgat tcctcttgag tacttagaaa
    12001 tttcttgtga aatcattgaa tatacaaaag aggctctaca agtccagttg aatgattctg
    12061 tgtatattgc attgacggat catttgtata cggctatcga acgtcacaaa atgggaatat
    12121 ttgtaccaaa tgtattgctg tatgatatca aacaactatt tcctaaagag tatgccatcg
    12181 ggaaaaaaaa cagtgaagaa aatctcggat aaataccaca tcaagttatc agaagatgaa
    12241 gccggattta tcgcattgca tttagtcaat gcacaaggca ttcaaagcca acaagacaat
    12301 acctacctgt tcactataac aatacaggat attctaaata tcgtccgcta ttactataag
    12361 attacatttg atgaagattc agtccatttt tttcgattcg tcacacactt acgttttttt
    12421 ctgacacgcg tcctagatgg agaaaaatca gaagtgggag aagtttctga ggaattgttt
    12481 caggttattc aaaaaaaata taaggatacg tttggttgcg ttgagaaaat agcagacttt
    12541 ttagccgaga cgttcaacta ccagatgtcc acggacgaaa aaatgtattt aacgatccat
    12601 actgcgcgtt tagtgcatga gaatcgttgt aaataaataa aaaaaggagg ataaattaac
    12661 aagaacgtat gaaataaggg tagtgacatt cagttggcta aaccttccac taataaattg
    12721 gagggaatag aaatgggaaa ataccaagaa ttagcgagaa aaatcgtaga aaatgtcggc
    12781 gggaaggaaa atatcaatgg tttgacacat tgtatcacaa ggcttcgttt caaattaaaa
    12841 aacgaagaaa aagcaaatga tgagatcttg aaaaatatgg acggtattgt aacggtaatg
    12901 cgagcgggag ggcagtatca agttgtcatc gggaatcatg tgccagtcgt gtttgaagag
    12961 gttataaaag caggaaacct tacttttgat gaggctgttt caacagaaaa aatgagaccg
    13021 tttgatatgc ttattgatgg aatatcgggc tgtttccaac cattccttgc tatcctagct
    13081 gctgacggga tgattcgtgg actgacagca ttccttgtct tcttaggcgc gtttgaccgc
    13141 ggttctggca catttgttat gtttgataat atcggtgatt ctgtattcca atttatgcct
    13201 gttattatcg gtttaacagc tgcccgtaaa tttaaagtaa atgaattcgt agggatgttg
    13261 cttggcgcag cattaatgaa tcctagcttg tcgctggaag ctttgagtgg tgcagcagaa
    13321 gcaccactaa cgaccatatt ttctggcact atttttgaag cacctattta tcaaacagta
    13381 ttcggcattc cctggattgc gcgtaactac gcttcttctg tcattcccat tatctttatt
    13441 gtgttgttag ctagccaaat tcagaaacca attaaaaagt tagtacctga gatgatcgcg
    13501 aatttcttcg ttccattctt caccgttctt attacaatgc ctttaggttt tttactcgtt
    13561 ggaccagtat tcacattcgc aactgatatt ttaatggctg gatttgaaac acttttagca
    13621 ctttcgccag ttatttatgg agcaatcgta ggcttcttct ggcaaattct ggtgatgttt
    13681 ggtctccatt gggcaatcgt accaatggga ttgatgcaat tttctgtgaa tggttggcaa
    13741 aatattatga cacctgttgc agtagtgtct tttggacaaa ctgcagcact taccgcactc
    13801 tactttaagc ttagaaatcc aaaagacaaa gcaattgcaa taccagccat tgtttctggt
    13861 attgtgggga ttacagagcc agctatttat gggtttacat tgccacgtaa aaaaatattt
    13921 atttttacct gtgtcggtgg tgcgttaggg ggcgcgtata gtgggttaat gaatttaact
    13981 tcttggaatc aaggtggact aggcatcttt acaattccca actatattag accagatggt
    14041 gatttaacag atgtgattaa tgtattgatt gggatcgcca ttgcgatggt ggtatccttt
    14101 gcgctgactt ttttcttttg gaaggaggaa gcagatgaaa cagatgatag acagaaaaga
    14161 tcaggtaaag aaattgtaaa aacaccgata caaggacaaa tcgctccact gaatgcagca
    14221 aaggatgcag cttttgcaca aggaacacta ggtcgaggaa tcttgatcta ccctgaaaaa
    14281 ggagaagtac gtgccccttt tgacggaaca gtcatgtccc tgtttccgac gaaacatgca
    14341 atcgggatgg tttctgaagc aggtctggaa ttgctgattc atgtcggatt ggatactgtt
    14401 cagttggaag ggaaatattt tgaaagcttg gtgcagcaag gagaaagagt gaaacaaggc
    14461 gatctgttgc ttcgcttcga caaaaagaaa atcgaagagg aaggatacag tttagaaaca
    14521 cctgtgattg tcatcaatta catggattat ttggatattt tggaaaatca aggggaaacg
    14581 gtcgggccag acgatgcact tatcaccgca ctgacctgaa cggttaggtg aaagaatgga
    14641 ctaggcttaa ctattctttt tagtccactt ctttattttc aaaattgaaa ggctctttca
    14701 tgatggctga gctgataggg cgtttatcaa atttttgtcc tacagaaatt agatggacta
    14761 aattctgttg ataattttct gcaaaaacac aactatataa cacgtctaga agataacaaa
    14821 tcgatgtatt gatcgtaaaa ttaccaattt tcgaatacag tcgttcgcgt gtcgtaagtc
    14881 gcaaagcggc tgtactcatt gaagatagcg ttgaatcacc gatactggtc aaagctaaaa
    14941 ttggcacatg attttgtttc aatatttctg cggtacgaag gatcacattg ttttcacccg
    15001 tataagaaat cagaatccca cacatatcac ttgtgcaatt gtacgcttca tagaacgatt
    15061 caccaaaagt ggtgacaatc gtgacatcca ttttgatgcg cttcattttc agcatgaaat
    15121 cttgagaaat caaagtattc gagttactgg cgaaaatcac gatttttttt gcttgaagca
    15181 ttagttgttt ggctttttgc agttggtcat gatgaatgag agaaagtgta tcttgaatcg
    15241 tcatctgttc taaagaagcc attttatttg cgatcgtcat aataccgtct gtggtggaaa
    15301 aaggaagatt cgcatctacg tcttgaaaat tcccttcaag ataggctgtt tcagctaaaa
    15361 aagcattacg aaaactgacc cagccatcaa aacccatttt ttttgctaca cggatgagtg
    15421 tggacgggtg gacataacat cgctcagcaa tctcttggat ggtcatttcg ccaagtgctg
    15481 gagaatcgct taagagaaac tgaatcactt cattttctga aggagaaaag gagatttctt
    15541 tgattttttc acgtaataac atgtagatac cttcttcttg tttttttacg taaatcataa
    15601 cttttttgaa aatgatttgt aaacggattt atgttatata
//
LOCUS       DAZKCH010000063        15255 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000063 DAZKCH010000000
VERSION     DAZKCH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.063"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..1021
                     /locus_tag="ACG84X_002051"
     CDS             2..1021
                     /locus_tag="ACG84X_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFP9127895.1"
                     /translation="MSIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDHQLIT
                     GKLMNSDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGWLFFF
                     TSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNKSILFVVIGMI
                     ISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRPYRSV
                     FLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSMTNIL
                     LFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLFFLTV
                     RRLKR"
     gene            1018..1785
                     /locus_tag="ACG84X_002052"
     CDS             1018..1785
                     /locus_tag="ACG84X_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFP9127896.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALIVLPLTCVTTAYLFTKKKEQLKME"
     gene            1885..3453
                     /gene="liaX"
                     /locus_tag="ACG84X_002053"
     CDS             1885..3453
                     /gene="liaX"
                     /locus_tag="ACG84X_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFP9127897.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDKASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQALEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            3750..4070
                     /locus_tag="ACG84X_002054"
     CDS             3750..4070
                     /locus_tag="ACG84X_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFP9127898.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            4070..4420
                     /locus_tag="ACG84X_002055"
     CDS             4070..4420
                     /locus_tag="ACG84X_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFP9127899.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            4587..5525
                     /gene="hprK"
                     /locus_tag="ACG84X_002056"
     CDS             4587..5525
                     /gene="hprK"
                     /locus_tag="ACG84X_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFP9127900.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            5540..6370
                     /gene="lgt"
                     /locus_tag="ACG84X_002057"
     CDS             5540..6370
                     /gene="lgt"
                     /locus_tag="ACG84X_002057"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFP9127901.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            6414..7439
                     /locus_tag="ACG84X_002058"
     CDS             6414..7439
                     /locus_tag="ACG84X_002058"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFP9127902.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            7454..8392
                     /gene="galU"
                     /locus_tag="ACG84X_002059"
     CDS             7454..8392
                     /gene="galU"
                     /locus_tag="ACG84X_002059"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFP9127903.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            8517..8957
                     /locus_tag="ACG84X_002060"
     CDS             8517..8957
                     /locus_tag="ACG84X_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFP9127904.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            8960..9562
                     /locus_tag="ACG84X_002061"
     CDS             8960..9562
                     /locus_tag="ACG84X_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFP9127905.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQGLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(9625..10728)
                     /locus_tag="ACG84X_002062"
     CDS             complement(9625..10728)
                     /locus_tag="ACG84X_002062"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFP9127906.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            10938..11939
                     /gene="ccpA"
                     /locus_tag="ACG84X_002063"
     CDS             10938..11939
                     /gene="ccpA"
                     /locus_tag="ACG84X_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFP9127907.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            12294..12689
                     /locus_tag="ACG84X_002064"
     CDS             12294..12689
                     /locus_tag="ACG84X_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127908.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREMQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTGSYRIVILMTNKQDQSIYFSYSFWKERNEIGSY
                     GIVDEKKQKEGNTLNKVKVTYSNGNEESI"
     gene            12689..12940
                     /locus_tag="ACG84X_002065"
     CDS             12689..12940
                     /locus_tag="ACG84X_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127909.1"
                     /translation="MITDKQYSELSDAVYWLDPKHRDYVPEMQENLSFKINGTMYKIL
                     KIKNSFDGMQAMAVAPIVHSKLEKNFKNKKIPANFRVLK"
     gene            12983..13378
                     /locus_tag="ACG84X_002066"
     CDS             12983..13378
                     /locus_tag="ACG84X_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127910.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGSYGALVTMTNNEGKSVYFDYSFWKERNELGGF
                     GIENRAVQKTGVTIKRVKVIFSNGQEELV"
     gene            13375..14631
                     /locus_tag="ACG84X_002067"
     CDS             13375..14631
                     /locus_tag="ACG84X_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HFP9127911.1"
                     /translation="MTINDKHYNDISEKVYWLDPKYPRYNEGYKKNSVKEFAGMEFQI
                     LQIKDSLDGMQAMSVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            14643..14966
                     /locus_tag="ACG84X_002068"
     CDS             14643..14966
                     /locus_tag="ACG84X_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127912.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            14959..15225
                     /locus_tag="ACG84X_002069"
     CDS             14959..15225
                     /locus_tag="ACG84X_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127913.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNYQ
                     MTAEEAAQEFSNRHVHLKGSVKGQFAEKLTELFQRQEKKLKQFR"
BASE COUNT         5242 a         2580 c         3225 g         4208 t
ORIGIN      
        1 aattagcatc atcactatat tttttatttg tgtgcttact tcatgggtta ttcagcatca
       61 agccgcttta tatgaagtac ctgtcatcga gatagaaaaa gtacgaataa aagaggatca
      121 tcaattgatt acaggaaaac tgatgaactc ggatcaaaaa ggagaatcga tttatttatc
      181 ggttccttat caaaaaaatc aaatagaaac agcaaatata aaagcgagac aaatgtatct
      241 agtccaaatg catggagatg aatggcagct agtagcaaaa aaaaatgatg gctggctttt
      301 cttcttcaca agtatcttca ttggcgccat gttgcttatt ggcggaaaac agggtctatt
      361 tgctttagga agtctcatca tcaatatcgt tttactttta cttttgttgc tcatctttac
      421 taaaacagaa gggatttctc tattaaataa atctatcctg ttcgtcgtta tagggatgat
      481 tattagcata ttggctttag atggatggaa tagaagcagt ataatcaaaa tttcagctgc
      541 agttacgagt gtttttttag cattttttat ttgtcttttg acaatgaatc attggaaaga
      601 ccaaggactg cgctatgagg aactgaatta tctgacacga ccgtatcgtt ctgtttttct
      661 ttctagcgta ctgattggaa cagctggagg aacactcgat accgttatca cagtcattgc
      721 gacattagaa gaattgacta agcgacaacc agaaataaca gcgaaacagt tatggctttc
      781 aggaaggcaa gtgggtcgag atgtgattgg ctcgatgacc aatatccttt tgttcgtcta
      841 tatcagtggg tcagttccat cgcttctttt atatttagga aatcaatggt ctttcaaaga
      901 aacgatagaa cagcatttat cattggaatt tttacgcgtc attgctggca gcttaggaat
      961 agtattatcg atccccatct cggtcctctt ttttctgact gtaaggaggc tgaaacgatg
     1021 aatgtactta ttatacttgt tgggatttta gcaatcagcg tgctacttat tggcggtacg
     1081 caaggtatgt atattctttt aggcttattc atcaatttag ggatcttttt cctgttgtta
     1141 ttcggttatc atcagaagtg gccgatactg gcattgtcgg tcataggatt tttattgatt
     1201 gctgtggtta tcttattttt tatcaacggt tataatctaa aaatgcgtgc agcttttgtg
     1261 agtatactga tctttttatt ttgtttccta ctattgcttc ctatcactga ttttttagcg
     1321 atccaaggtt ttacatcggt agaactagaa gaattatctg gcttagataa gactttagcg
     1381 attgatttta gattacttac gagatcgttg cttctgatta gtcttagtgg tgctgtttta
     1441 gatgcgagtg tagcaatttc tagtgggaca ttcgaagtat atcaggcaaa tccgcaatta
     1501 tctttttacc aattgcgcca ttctagtttc gctattgcta aaaaaatatt ggcgtcaaca
     1561 gtaatgacac ttctttttgc attcatggga agttctttag cgttgatcct ctggtttatt
     1621 gatttagaca ttccttttca gcaagtgatc aatgaaaaat catttgttct agaatatacg
     1681 atggctattc ttaccacatt gtccgcacta attgttcttc ctttaacctg cgtgactaca
     1741 gcatatctct ttacaaaaaa gaaagaacaa ctcaagatgg agtaaaagtt acaacttaag
     1801 tcctatgaca tttttactga atcagtgcat aatatggatg taaggaaaag cttgcaaaca
     1861 attttgctta aggaggcaat ttccatgaaa gaaagagaac gtattttaga tttagtgaaa
     1921 aaaggaatcc tttcgactga agaaggctta gatttattag aaagcatggc aactgaaaaa
     1981 gacgaaaagc aaatcaaaaa agaagcagac aaggtaactg ctagtcataa agaaaaagat
     2041 aaggcaagtc aattgatcga taaacttgaa aacggcgaag aagaaatttc tgagccagtt
     2101 gatccaaagg aaagagaaag acaagatcaa gaaaacttag aaaagatctt agatgaacta
     2161 gcaactgaag cgaataaaac ttcggcgcgt ctagatgaag taaatgctca attcgctgac
     2221 aataaggcag cacgcaatga gaaacaggaa gcattgatgc agctgaatac aaaagaagaa
     2281 ttaggcgagt tgacagaaga agaattagca cagcgtcagg cgttagaggc agaaatcaaa
     2341 gagttagaag ctagtggcga tacactgtta gaagaacaat tgaaattaga agcagaatta
     2401 aaagatatcc gtaagaatca atggtctgag aaaaaagaaa cgtttactga taagtttgaa
     2461 ttgccagatg attggaaaga tcaagcaaca gatacactga atcaagtagg cgaaaaaatg
     2521 tcagaagctg gatcacagtt aggcaaattc ttgaagaaaa cattccaaac tgtttcagaa
     2581 acagtgaatg acaacatgga atggaaagat gtcagcttac gtgtccctgg gattgcgaca
     2641 acgaaatttg agcatgaatt ttactatgaa gctcctgcag caagtatcct tgatatcaag
     2701 gcagcaaacg gaaacgtgac gttaaaaacg tgggacagca acgatgtgaa agttgaagct
     2761 aagatcaaac tttacggaaa aatgggtgct gaaccatttg aagcattctc tgaacggagc
     2821 cagattgagg ttaatgaaga tcatatctcc ttccaaattc caaataaacg tgtgcgtgca
     2881 gaccttgttt tctacttacc taaacgagta tacgaccacg cagctattaa acttctaaat
     2941 ggcaacatca tgattgaaac attggaagct aaagatattt atacaaaatc tacgaatggt
     3001 aacatcatcg tggaccaatt aactgcaacg atgctggaag tagaaggtgt aaacggcaat
     3061 atcgatattc gaaacgggaa catcttagat tctattatcg aaacagtaaa tggtacagtg
     3121 acatttggtg cgacagcaga aaatctttct gtgtctttag taaatggtga tgtacgtctt
     3181 acgattaaag aagataattt gaaaaaagta gaagcaagtt cagtgaacgg aaatgtcaaa
     3241 gtcgctttac cagatggcat cggtttggaa ggacatgcta aaacaagtct tggaagtatc
     3301 aatagccgtc tgtccaatta cgaagtagtt cgtgagaaaa aagaacggac aaaccaaatg
     3361 ttgcaattcc gtcgtgtttc agatgatgag atcgcgcaag tgcaactttc aacgacaaca
     3421 ggaagtatct atttaaaaga tacagataaa taaagaggtt gtgaaagaga tgttcagcct
     3481 tgagcaataa gaagcgattt tgtaaaatag cttcccctat tttacaaaat tgtgccttat
     3541 tgccgatagt ctatctcttg aacaccgttt accaagagat tatgaacctg ccaattatcg
     3601 ccgagtcaca aggaataatt tcagaaaaag ctcgtcacgt tttatgaata tggtaatttg
     3661 tgaccgagaa ttttgcagaa agacaccgat taagaagaag gttgtcacaa cgattttctt
     3721 catttaaaat agtagaacag aggtgagaca tgatgaaaaa aaagttgaca aaatctaata
     3781 aaaatgttgt tttgacaggg actttagcag gaataggaga atacatcggg attgatccga
     3841 ctgttatccg tgtgctttat gtattcctga gcttagttgc ttttggaagt ccaattattt
     3901 tatacatttt attagctttg attatcccat ctgcgcgttc tgcacgaaca aactatggac
     3961 ataacaatgc atattatgaa aaaaacaatt atcgtgaaca aactcgtgaa caaacaaaaa
     4021 aacgcaaaga agcggaaaaa atcgatgatg acgaatggag tgacttttaa tgtcgtactt
     4081 tcaacgtatt ttagttaata cgttaacatt catatcattg gctgttcttt ttcctgcgat
     4141 ggtccatgtg agcagtattt ggacggccgt tcttgccagc ttcgtattgt ctgtgttgaa
     4201 tatgtttgtc aaaccgattt tgacgatact gtccctgccc tttacattag tcacattggg
     4261 attgtttacg tttgttatca atgcagcgat tcttaaaatg acctcctttt ttgtgggagc
     4321 agaacatttt agtttttctt cattcggtgc agcgttgtta gtagctatct tgatgtcgct
     4381 tgtcaatgta attgtcagcg aacataacag tagaaaataa aagaaagctg tgccgaacta
     4441 tcggcgcagt ttttttattt agaatcagga atgcgttttc tattacattg gtaattaaat
     4501 aaaaacgttt tttttaattg gtagtacttt tggctagaca atgataaaat gatagagaac
     4561 actctaatag aaatgaggta gcatgaatgt cagaagttgt aaaagttagc caattagtga
     4621 aaaaattatc tttggaaatc gtgacaggcg acgagaaaag cttagaccgt gtcatcgtaa
     4681 ctggggacat ctcacgccca ggactagagt tgactggtta ttttaattat tattcccata
     4741 atcgtttaca gctatttggc agtaaagaaa tcagttttgc ggaacggatg atcccagaag
     4801 agcgtttgat catcatgaga agattatgta gtgaagatat gcccgcattt attatttcaa
     4861 gaggattacc agctccagaa gaaatgatcc aggcagcaaa tgaaaatggg atagctgtac
     4921 tgcgttctcc catctcaact tctcgtttat taggagaatt atccagttat ttagatggtc
     4981 gccttgcccc tcgaacaagt gtccacggtg ttttagtgga tgtttacgga ttaggtgtac
     5041 tgattcaagg tgacagtggg ataggaaaaa gtgaaacagc gttggagttg atcaaacgcg
     5101 gccatcgatt gatcgcagac gatcgagtag atgtttatca gcaagatgaa ttaacggtga
     5161 tcggagaacc gcctaaaatc ctggaacatc tgattgaaat ccgaggaatc gggatcattg
     5221 atgtaatgaa tctttttggt gcgagtgcgg tacgtggctc tatgcaagtc cagttggctg
     5281 tttatctgga agcatgggca aaagataaga aatacgaccg tctgggctct gaagacacga
     5341 ccgttgaaat cgcggaagtg ggcattccac aaataaaaat ccctgtcaaa acaggacgaa
     5401 acgttgcaat catcattgaa gtagccgcga tgaatttccg tgcacgtaca atgggctttg
     5461 acgcaacgaa aacatttgaa gaaagattaa gtcgcttgat tgaagaaaac tcaggcaacg
     5521 actagcaagg agtgacaata tgttagcaca aatcaatcga gttgcttttg agcttgtagg
     5581 gattcctatc tactggtatg cattgatcat cgtatcaggt atcattatcg ctatgtggct
     5641 tagcagcaga gaggctgttc gggtaggatt aaaagcagat gatgtgacag attttatgtt
     5701 gtggggattg cctatctcca ttattggcgc tcgcttatat tatgttttat ttgatcttcc
     5761 ccagtatata gctgatccaa tccaaatatt caatatccgt tcaggaggct tagctattta
     5821 tggcggactg attgcaggcg cgatcacgct gtattttttt actaaatatc attttatttc
     5881 tttgtggact tttttagata tcgctgcacc aagtgtatta ttagcacagg caatcggtcg
     5941 ttggggaaat ttcatgaacc acgaagcata tggaccagac acgacgcgaa gcttcttaga
     6001 aagtctgcat ttaccgcaat tcatcattga taatatgtat atcgaaggga tctatcgtca
     6061 accaacattt ctttatgaat cactttggag tttgattgga tttattttgc ttttgttttt
     6121 acgaaagaaa ccacaccttt tgaaaaaagg cgaagtcctt ttatgttatc taatgtggta
     6181 tagtttcggg cgtttcttta ttgaaggatt acgtacagac agtctttact ttttaggtgt
     6241 gatccgtatt tctcaattat tatctgctgt gttatttgtc ggtacattga ttctatttat
     6301 ttggcgcaga aaaaaaggaa atttaccgga ttatgaccgc tcattaggaa aaaatcaaca
     6361 aattatctga tttttagagc gttaaaaatg aaaaaaattt caggagtggt aaaatgaatt
     6421 atagagtagc ggttttagga ccaggctctt ggggtactgc tttggcacaa gtcctcgccg
     6481 aaaacggaca tgacgttcgg atttggggac atcgtgcttc acaagtagaa gaaatcaaca
     6541 cccaacacac gaatcaacgt tatttaccag atcattatct acccgattcc atccaagcat
     6601 tcaccaatat ggaagatgca gtaaaagacg cagatgcggt gctattcgtc attccaacga
     6661 aagcaatacg ttctgttgca aaagaactag tgcctaaatt gaatacaaag ccagtgatca
     6721 tccatgcaag taaaggatta gaacagggaa cacataaaag gatctctgac atcttgttag
     6781 aggaaatccc agcagaaaaa agaaaagctg ttgttgttct ttctggacca agccatgcag
     6841 aagaagtagc aaaacatgac atcactacga tcacagctgc aagtacagat gcaaaagcag
     6901 caaaatatgt acaagagctg ttcatgaata attattttcg gatctatacc aatcctgatg
     6961 tgatcggtgt agagatgggg gcagctttga aaaatattat tgctattggt gctggcgcta
     7021 ttcacggctt agggtttggc gataatgcaa aggcagcaat catgacgcgc ggattagctg
     7081 agatcagccg tttaggtgta gcaatgggtg ccaacccgct gacctttatc ggattaagcg
     7141 gaataggcga tctagtcgtt acttgcacaa gtgttcattc taggaactgg cgcgcaggca
     7201 acttgttagg acaagggcag cccctagaag aggtgctagc caatatggga atggtcgttg
     7261 aaggtgtgaa tactacccaa gcagcgatgg aactagccca aatgatggaa atcgaaatgc
     7321 ccatcactca aacaatctat gaagtgctgt atgaacaaaa agaaatcaaa acagccgcaa
     7381 aagaaatcat gttacgtgat ggaaaaaaag aaaatgaatt ctcattaaca attttttgaa
     7441 ggagcgaatg tatatgaaag ttaaaaaagc agttattcca gcagcaggat taggaacaag
     7501 atttttacca gcaacaaaag ctatggcaaa ggaaatgttg ccaattgttg ataaaccaac
     7561 aatccagttc atcgttgaag aagcgttgaa atcaggtatc gaagacatct tgatcgttac
     7621 aggaaaagct aaacgaccaa tcgaagatca ctttgattca aatattgaat tagaaacaaa
     7681 cctaagtgaa aaaggaaaga ccgaattatt gaaattagta gaagaaacga cagatgtcaa
     7741 cttgcatttc atccgtcaat ctcatccaaa gggtttagga catgccgttc ttcaagcaag
     7801 agcctttatt ggaaatgaac catttgtcgt tatgctaggc gatgatataa tggaagacga
     7861 agtaccattg acacagcaat tgatcgatga ctatgagcgt acacacgctt ctacgattgc
     7921 cgttatgcaa gttcctcacg atgaaacttc aaaatacgga atcatcaacc caggggaagt
     7981 actggaagat gggttataca atgtcaaaaa ctttgttgaa aaaccagatc caagcaaagc
     8041 accaagtgat ttagctatta ttgggcgtta cttattgact ccagaaatct ttgatgtatt
     8101 atcagaacaa caaccaggtg ctggaaatga gatccaacta actgacgcaa tcgatacgtt
     8161 gaataaaaca caacgcgtat ttgcccgtaa attcacaggt aaacgttatg acgttggtga
     8221 caaatttggt tttatgaaaa caagtattga atatggtctg acacatccag aagtaggggc
     8281 acctttgcgt gaatacatca tgtctttagg taaaacatta gaagcagaag gaagcaagat
     8341 caatcataat ccaaaaggaa taacagaaat caaagaagaa aagaaaaaat aatctttttt
     8401 tctaacgagc ttcagctgct aattgaataa aaagtagttg aagctcgttt ttatttgttt
     8461 aaaaaacacg aaaatgctat ccttatagaa aagagagaca agaagggagt ttgatcatgt
     8521 caggaggaga aattgcagga ttgatcgcag caatcgcctt tgcgatactt gtcgttttca
     8581 tcgttcgcgt attgttgcaa gtttccaaaa ctttagaaaa agtagaccag actgtcgcag
     8641 aagcaaatac gacaattgag atcgtcacac aagacgtaga tcttttatct agacaagtag
     8701 aaggcttgct agtcaaaagt aatgagctgc tcttggatat caatggaaaa gtcgcaacga
     8761 tcgatccatt gttcacagca gttgctgatt taagtgaaag tgtatcggaa cttaatcatt
     8821 ctagtaaaaa catcgtgacg aaagtcggcg gaatcggaaa aacgacagct aaagcgactg
     8881 ttgccggaaa agtcggtgga acagcgatga aattttttaa aaacaaaaaa catactgaaa
     8941 cgacaggagg aaaataagaa tggctaaaaa aggtggattt ttattaggtg cagtagttgg
     9001 aggtacagcc gcagcaatcg ccgcattatt gttagcaccc aaatctggta aagaacttcg
     9061 ggatgaattg gctgctcaag cagatgattt gatggacatg gcttcagatt acacagatat
     9121 ggcaaaagaa aaatcatctg agttaacagg tattgcaaaa gaaaaagcgc aaggtctttc
     9181 tcaacaagca ggggatctag caggcaatgt taagcagaag gtaagtgaat cagcagagga
     9241 agcaggaagt gaatcagatg atatcttgtt aaacctcaaa gaacaatcag ctgatttatc
     9301 taatcgtttc aaaaaaacag cagaagatct gaaaaagcca gcagacgaat taggtagtat
     9361 tgctaaagat acttcagaag atatcatgat cgatgtaaaa gatgctgcag ataaagcagg
     9421 agagacggtc aatgaaggaa tgtcagaagc aaaaccagtt gcagatgaca caaaagaaat
     9481 gttgaaaatg gcaaaagaag atgcaaaaga agctaaaaaa gaaatgaaag atacaatgac
     9541 agattcgact accaatcact aagattactc atttctagaa taaaaaaggt gagagcggac
     9601 cagctctcac cttttttatt ttcattactc taaaacaagt aattcttttg gtgtagtcgt
     9661 gaatggcaca caaccatcac ttgtcacata cacacaatct tcgatacgta cccctacttt
     9721 ttcaggaata tagattcctg gttcaagaga gaagcacatc ccttcttcaa tcactaagtc
     9781 gtttccttct acaagagaag ggaattcgtg gacggttgtt ccgattccgt gacctaaacg
     9841 gtgattgaaa tattcgccgt agccatagct gttgatcacg tttcgtgcga tttgatcaag
     9901 ttcacctgct gtcacacctg ggcgaactgc ctcttgtgcg gcaagctgtg cttcaagagt
     9961 gatgttatag attttttctt ggaactcagt tggtttttga taagcaactg tacgagtagc
    10021 atcactgcaa tagccattcc aaataacgcc aagatcgaat aacactagtt catttggtga
    10081 aaccttcgtg cttcctggtg taccatgagg gcttgcagca tttgctcctg caaggactaa
    10141 tgtgtcgaaa gacatttgtg aaacaccttg tttttttaat tggtattcga tttctgcgat
    10201 aattgcttgt tcagttacgc cttcttttac tgttttgaag ccaatttcaa aggcaacatc
    10261 ggcccattta ccagcttcga tcagtttgtc tttttcttct accgttttga tcagttgcag
    10321 acgctggata atagaagtta gatcggtgta agaatctgta cctgtcaaga tatcagagat
    10381 agcatcgaag cgatcgacag tcagagcatt cttttcaata cctacattac caggttgccc
    10441 atagcgtgcg cgaagctctt ttccgatgat ctcccaagga ttttcgctgt ctaagtagcc
    10501 acgtacatcg tacgcccagc tgctgttttg agcatcttca acttccagag caggagtgaa
    10561 aaggaaagga tcttgttcca gagggataaa aagagctagt acacgctcgt gaggatcact
    10621 ttcatatccg gaaaagtaag cgatgtggcc agggtcgctg atataagcca attctacttg
    10681 gtgttgtgcc atccattgac gtagttcatt gatttttacg ttattcattt ggcaacctac
    10741 tttctaaatt aattttgtat tcaataattg taccactgat tgattaaaag accaacgttc
    10801 ttaaaactga aaaaagtaaa aattttcatg aaaacagaga taaaacggtt gcaattgttg
    10861 agattatttg atatcctatt ttagaaatgt aagacgtatt ttcagaaaac atataaaata
    10921 tgaataggag aacacaaatg gaaaagcaaa caatcactat ctatgatgta gcgagagagg
    10981 caaatgtttc gatggctact gtttcacgtg tcgtaaatgg caatccaaac gtcaaaccag
    11041 caacaagaaa aaaagtcttg gaagttatcg atcgcttgga ttatcgtcca aatgcagtcg
    11101 cacgtggctt ggcaagtaag aaaacaacaa cagttggggt aatcattcct gatgtcagca
    11161 atatgttctt tgcctcttta gcacgtggta tcgacgatgt ggcaacaatg tacaaataca
    11221 atatcatctt agcaaactca gatggcaacg atcaaaaaga agtcaatgta ttgaataatt
    11281 tattggctaa gcaagtggac ggcgtgatct ttatgggtca ccatatcaca gacgaaatcc
    11341 gtggagaatt ttcacgttca aaaacgcctg ttgtactagc tggttccatt gatccagatg
    11401 aacaagtagg tagcgtaaac attgattatg tgtcagcaac aaaagatgca gtaaataaat
    11461 tagcaaaaag cggcaataaa aaaatcgctt ttgtcagcgg tgcgctgatt gatcctatca
    11521 atggtcaaaa ccgtctaaaa ggctataaag aagcattaag cgaaaacaat ctaccatata
    11581 gcgaaggatt gatttttgag gcacaataca actttaaaga tggtctgtct ctagttgacc
    11641 ggatccataa tagcggtgca acagctgtct atgtttcaga cgatgaatta gccattggta
    11701 tcttggatgg tttattagac cgcggcgtaa aagtaccaga agaattcgaa atcatcacaa
    11761 gcaacaattc tttactgaca gaagtagctc gtcctcgttt gacaagtatc acacaaccat
    11821 tatacgattt aggagcggta tccatgcgcc tattgacgaa aatgatgaat aaagaagaag
    11881 tcgaagaaaa aacgattatc ttgccttatg gaatcgaaga aaaaggatca actaaataat
    11941 aaaagatcaa tcatttaaag gttgttccaa aagtggtcaa cttctggaac aacgtttata
    12001 cgagaaaggg ggttatgaca aaattttgtc ataacccctt tttttttgtg actttaaaaa
    12061 aagagaaaat ggcggaaaca aaccttacgt ccatcgtata cgacacaatc tgtgcgtaga
    12121 tgctacattt tgttcactac tatcaaaatt actttaaaat gaaaacgtga taaaaaagaa
    12181 agtagaaaag tagataagta actctaaaaa atccaaaaaa atccaggctc gattgcgtac
    12241 ttatcttaaa ggagaaacaa tccatcatat ataacccgaa aggagacttc tatttgccta
    12301 agaaaagacg aaagaccata gtcatcattt tgaccattct tactatagga atcggaggga
    12361 aattttacat ggacaaaaga gaaatgcaaa gacagaaaga tttactcgca gtagaaaaac
    12421 agtccgtcaa agttctgaaa aatacctttg cggatatcaa ggaagtgaag attgaaaaat
    12481 ctgctcgaaa tgaaatgacg ggttcatacc ggatagttat tctaatgact aataaacaag
    12541 atcaatcgat ttatttttct tatagttttt ggaaagaaag aaatgagata ggaagttacg
    12601 gaatagttga tgaaaaaaag caaaaagaag gaaatacgct caataaagtt aaagtaactt
    12661 actctaatgg aaatgaggaa agtatttaat gattactgac aaacaatata gtgaattaag
    12721 tgatgctgtt tactggctag atcctaaaca tagagactat gtacctgaaa tgcaagaaaa
    12781 tttaagtttt aaaattaacg gcactatgta taaaatccta aaaatcaaaa actccttcga
    12841 cggcatgcag gcgatggctg tagcgccaat cgtccatagc aaattggaga aaaatttcaa
    12901 aaataaaaaa attcctgcaa actttcgcgt acttaaataa tgaaggtgtc aatacttaca
    12961 taaaaagaaa ggaggcacgt tcttgtcaag gaaaataaga aaactcagct tagccatttt
    13021 attaatcgtc atattaggga tcggagggaa agtctatatg gacaaaagag aagcacaaag
    13081 gcagaaagat ttactcgcag tagaaaaaca gtcagtcaaa gttctgaaaa atacctttgc
    13141 ggatatcagg gaagtgaagg tagaagaatt taaaaaaaac cctgttaccg gaagttatgg
    13201 tgcacttgtg acaatgacaa ataatgaagg gaaatctgtt tattttgatt atagtttttg
    13261 gaaggagaga aatgaacttg gtggttttgg cattgagaac agagcggtac aaaagacagg
    13321 agtcactata aaaagagtaa aagtaatttt ttctaacgga caggaggagt tagtatgaca
    13381 ataaacgata agcattacaa tgatattagt gagaaggttt attggctaga tcccaaatat
    13441 ccccgctaca atgagggata caaaaagaac tctgttaaag aatttgctgg tatggaattt
    13501 caaatcctac aaatcaaaga ctcattggac ggcatgcagg cgatgtctgt agcgccaatc
    13561 aagaacggta aagtggatct ttctcaagta gtgattgctt ttgcaggaac gaacttaagt
    13621 gattggaaag atttggaaac ggatgcaaga agtatcatga atctctacgg gaatagacca
    13681 ggagcaagtt tttctgaaaa agcaacaaca aacaagattt tatccgttag tggattgaaa
    13741 acagcggggc aaatcaattc agcgattgca tttgctaatg aagtaaaaaa ggaatatgga
    13801 gaagctgcta tttctactac cggccattca ttaggtggat tcttagcatt atatgtagca
    13861 gcagagaaac aatggaaaaa tgtcggcttc aacgggccgg acccgtatga tctcttatca
    13921 ccagaagcaa aaaaatgggt ggaagaaaat cccggtatgc tcaccaatta ccgaaatcac
    13981 gccgatttta tcggtaattt tggtggtaat ggcacaggtg ctgaagttcg gatcagtatg
    14041 gaaacagcat tcttgaatct gcttgcttcc cacagtttaa cctcttggaa gtttgatgaa
    14101 aatggaaagc tgattattcc tgaaaatgaa aacaatgtta aagctcgaaa acaacagaaa
    14161 gaaaaccaag cgacccagtt gttttcctat cagttgcaag aactgaacaa catacgtaaa
    14221 aaactacgat taagtggcgg ccggctgaca gttaatgaac aaatttactt agatgacaca
    14281 caagctaggt tagtagtgga aaagttatcg gcaaaaatga aaagcgctat ggaagaagtt
    14341 atccgcatca atcaaagagg aatttttgag ctagagaaaa aatggcaaga aggcttgcgg
    14401 caagcacgtg ttgtagcccc ttcgttgact gaacaggaaa tcatagaagc attagctagt
    14461 gtgggcgcca caaaagaaaa cttagtcgat tctgcgaaag aagtctatct gctacgaatc
    14521 aataaggcaa gacgtatggg ggaggccttt gatacattgg cgaaggagat ccaagacaaa
    14581 atcaatgaaa tcgtggcacg agatcgagaa ttagcacagc aattcaatta aaggagaagt
    14641 agatgaaact agaagaattg gaaagagatt atcgaagtga acgaagacaa ttagaagctc
    14701 aagaagatga attgatccac tttaagaatc aaggattacg attgatggag caagaggagc
    14761 agcgactgca tcatgtatta aagaacttag ctttagataa tgagcctctg tttcaagcaa
    14821 gacgaagtta ttcgaattat caggagcatt atcaacaagc cctacaagta gaacgacgaa
    14881 aactctatca gcagcaagat gaactagaac gttcctatcg tcaaaaaatc agacaaataa
    14941 ctatggagaa atcatcttat gaatgaattt ttaatgcaat tactaaaaga attagagaaa
    15001 aatctacatc gatcaaatgt acgttcagtt ggtatgggga tatctcagca aatttgggca
    15061 gaaaaacgat tgacagatca aaactaccaa atgactgcag aagaagctgc tcaagaattt
    15121 tctaaccgac atgtacactt gaaaggatca gtaaaagggc aatttgcaga aaaactaact
    15181 gaattattcc aaagacaaga aaagaaatta aaacagtttc gttagtaaag ttatatagaa
    15241 aaattttgtg aaaat
//
LOCUS       DAZKCH010000064        15072 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000064 DAZKCH010000000
VERSION     DAZKCH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.064"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            78..686
                     /locus_tag="ACG84X_002070"
                     /pseudo
     CDS             78..686
                     /locus_tag="ACG84X_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            706..1734
                     /locus_tag="ACG84X_002071"
     CDS             706..1734
                     /locus_tag="ACG84X_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFP9127914.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1731..2489
                     /locus_tag="ACG84X_002072"
     CDS             1731..2489
                     /locus_tag="ACG84X_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFP9127915.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2575..3315)
                     /locus_tag="ACG84X_002073"
     CDS             complement(2575..3315)
                     /locus_tag="ACG84X_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFP9127916.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3376..4629
                     /locus_tag="ACG84X_002074"
     CDS             3376..4629
                     /locus_tag="ACG84X_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFP9127917.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4924..5178
                     /locus_tag="ACG84X_002075"
                     /pseudo
     CDS             4924..5178
                     /locus_tag="ACG84X_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5300..5626
                     /locus_tag="ACG84X_002076"
     CDS             5300..5626
                     /locus_tag="ACG84X_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFP9127918.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5694..6407
                     /locus_tag="ACG84X_002077"
     CDS             5694..6407
                     /locus_tag="ACG84X_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFP9127919.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6717..7569
                     /gene="licT"
                     /locus_tag="ACG84X_002078"
                     /pseudo
     CDS             6717..7569
                     /gene="licT"
                     /locus_tag="ACG84X_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
     gene            7690..9555
                     /locus_tag="ACG84X_002079"
     CDS             7690..9555
                     /locus_tag="ACG84X_002079"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFP9127920.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9569..11012
                     /locus_tag="ACG84X_002080"
                     /pseudo
     CDS             9569..11012
                     /locus_tag="ACG84X_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            11120..11821
                     /locus_tag="ACG84X_002081"
     CDS             11120..11821
                     /locus_tag="ACG84X_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9127921.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            11947..12459
                     /locus_tag="ACG84X_002082"
                     /pseudo
     CDS             11947..12459
                     /locus_tag="ACG84X_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(12857..13066)
                     /locus_tag="ACG84X_002083"
     CDS             complement(12857..13066)
                     /locus_tag="ACG84X_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFP9127922.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            13307..13882
                     /locus_tag="ACG84X_002084"
     CDS             13307..13882
                     /locus_tag="ACG84X_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFP9127923.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            13882..14322
                     /locus_tag="ACG84X_002085"
     CDS             13882..14322
                     /locus_tag="ACG84X_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFP9127924.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            14338..15039
                     /locus_tag="ACG84X_002086"
     CDS             14338..15039
                     /locus_tag="ACG84X_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFP9127925.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5083 a         2501 c         3179 g         4309 t
ORIGIN      
        1 acctccagac ttcttgatag ctcaagtata tcttgaggtg catttgttag taaggtactg
       61 ttctatgggg cgcttaccca gaaaatcaac tttttgcagg agatgtatta gaaattgtat
      121 taaacgacca agcaggagaa gctgctgcta agggtgtgca gaacaagcca agtaccaacg
      181 atgaaattgg gaatcacaat ccaagtgata cgccagttgt ttatcatgat gccccgcctt
      241 ttgcacctgc tacgaagatt gtagtagaag gtggtctctc atttcttgcc ccttccaaac
      301 tcgattgtgg tcagatcaaa gcaactgggt tgacgcaaga agcatttggc caaatggata
      361 tacaggaaaa attatggatt tatgatcagc gagaaacaaa aagtccatgg atcttaacga
      421 taaaattatc tcagcctttc acaaccgatg caggattttc tatgcaggat gtcctatatt
      481 tcaagaaagc tgaggagtat caattagtga atgaagaaga actggaaatt gtcagaggac
      541 aaaattcaac gaatgtgcaa acagattatt cagaatattt aaataatggt cgggcgttta
      601 aacttgtctt aaccaaagaa aatcagatag ctggtaatta ctcagcagag atgacatgga
      661 cattagcaga tgcgccgaca gaataaagat caaggagaat gattgatgaa tcgaatatgg
      721 aataaaagtc atcgaaacaa ctgctcttta cttctgatcc ttctccttgg attcatcctt
      781 tggcagacac ctgtccatgc ctccgaattc aattttgcgg tagattttga attaccggct
      841 aatcagattg ataagaacaa aacatatata aatgtaagga tggagcctgg gaaaacacag
      901 gaaatcccct acacggtctt taaccgaaca gataaatcag taacagttga gacattgatc
      961 cactccgcta cgacgaattc aaacggtgtg atcgaatatg gagaatcaaa aagtaaattt
     1021 gatgaaacat taagttatga tatgaaaaac ttagcaaaaa cagtgggaga aataactgtc
     1081 cctcctcaaa gtgcggtcac tgagacactt tcactgaaag ctccagaaaa agagctggct
     1141 ggtgtggtcg caggaggaat cacgtttcaa gaaaaaaaag agaacgtttc taacaaaagt
     1201 acagttggtg tcgtcaatca gttttctcaa gtgaaagcaa tcttgattcg aaatagcgaa
     1261 aaagagtctt ccccaaattt gaaattaaaa aaaacttatg cggatcaaag cgatggaaga
     1321 aatgtgatta aggcgaatct tcaaaatcca aatgcttctt atatgttcgg cttgactaca
     1381 tcggttgaaa tctacaaaaa agaaacaaaa gagccttatc tttcaataaa aaaagaaaaa
     1441 atagatgtag cacccaatac aaattttgat ttacttgtcc cattagaagg aaaaaaatta
     1501 gctccgggac attatcaagc ggttgtgaag ggtgcttgga aagaaaaacg ctggaatctc
     1561 cataccgatt ttgaaataac tgatgatgca gcggaccaat tgaatgaaaa ggatattgat
     1621 ttaaaaaatc agccagaaac atttgactgg cgatggctga tacttgttgg agtcattctt
     1681 attggcttat ttgctggatt atttatttta aaagaaagaa ggaaaaagaa atgaaaaaaa
     1741 caattgcatt aagtaccgtt ctagctggaa gtctattatt atgtacacaa agtgtttttg
     1801 ctgagaataa gagctcagcc actacagaag gaacgatttc tgtaacaaaa ccagatgccg
     1861 caaatcctga agacgttgtt ccagttcctc ctgttgatcc aaatgatccc gatacgccgt
     1921 ttacacctaa cgaaccaaat cagggaacat ccggattact gacgattgac caagctccag
     1981 atcttgattt tggaacaatc aagttaggta cagcaaaaac agtatatgct gcattacaaa
     2041 acggaacgga cagtacaggg acagcaacac aagtacagaa tttcgtacaa gtaacggata
     2101 aaagcggaat ttatgccggt tggaaactat cagtcaaacg aacagaattt attggtacaa
     2161 catctgatac gaataaacta actggttcaa aggtgaaatt caaaaacgcc gtgattcgaa
     2221 atagcgcaac taatagcagt ggaacgccat ctactatttc tggtactggc gctgaaggaa
     2281 ttgagatccc agcagatcag gcagtagatc tagtaactgc aggagcaaat gaagggattg
     2341 gcacatggat ttattcatta ggagagaatg tggaacaagg gagacaatca gtggaattat
     2401 ttgttcctgt atccaattat gccgtagaca actacgtttc aacattcaca tggtcgttaa
     2461 cagatgctcc tacagaaggg aaagcgtaaa atcaaatcaa tgacttcagg gagtggagcc
     2521 gattcaaggc caactccctg aaatctgcta tgcttacgtc tcagctctta ttcatcaact
     2581 cgaagcagtt ttttggaagt catggaaacg ttcctttgtc ttttcaaaga tctttcgacc
     2641 aacgagtaag gagtcaccat tgaaaaattc taacacataa tgagcagaat caattttctg
     2701 caattgcgat aagttgatac agtaagattt taatagtaaa aagtaagcat acttttccaa
     2761 ctctgtcttc aattgtttta aagaagtatt cactaattta tcttctgtag ttgttttgac
     2821 cataacttgg tttttcaaac ctttgatact ttcaatatat aaaatttccc gaggatacag
     2881 gacgagactt ccaccttttt gatcaataaa gattttatcg acatttacga tttgctgttc
     2941 tttccaattg atctgttcta gcacttgacg aatttgttca gataaattcc tgtcttttct
     3001 gatatatcca atcggaagga ttttccgatt gatgatctct actgcaaaat tcgtataagc
     3061 ggtgaaaaaa acaatattac tatgtgcatt ttttttacgt atttgttcgg cgacatcaat
     3121 acctgtgagt gattgcttca agtcgatatc gataaagaaa acatcgtgat tatcaatagt
     3181 acccaactgg atcaactgat tgatttgaga gatagaagtg agctgcacga tattctcgat
     3241 atgatgattg accaattctt tgatgatcca ttcgctgtga aactggttat cttctatgat
     3301 aaaatacttt ttcatatgca ggctcctatt aaaaaaatat gtgtacattt tgaaacaaaa
     3361 caatggagga ataagatggt cgcaacagtg acactttatt tgacctttac tttgatttta
     3421 gatttaggta tctatttatt cttttcgaaa caactgctag taaaaaacag ctttggtttt
     3481 atagctttga tggtggtgac acttttattt cctatcccta aagtgagctt tccttaccta
     3541 gttggcttat tattgatgtt tcttttttat tttactacga aaaacctgtt tatcagctgt
     3601 ttgatcagta atcttttttt tgctatcact ggactcagct tttttctggt ttttgatctg
     3661 atggattatt taggaaagag acatcttgga acagcaagtt tttttgcact acttatcgca
     3721 tttattttct atctattagt aaaaagtata gacaaacaga cgagatttct caacttgctt
     3781 tttacttatc caactgaaca ctattttgga ggtatttgta ttttattaag ctggggcgtg
     3841 atttacttgg tattgggaag tgttcacttc cgctcatcta attatctgct tctatctctt
     3901 ttgtcgatag tcatcagttt tttttctttg tttttttcca ttatgttgat cagtttccaa
     3961 gtaaaagaaa gacaacatca ggaatcgctt caactgtatc aaataaatga agaatattac
     4021 catcatctag aggaattcaa acatgattat aaaagtctac tgttttcatt aaaaattact
     4081 cttcaggaaa ataaaaaaga aacgttggaa tttttagaaa tcttagaaga tcattctgca
     4141 gctatttttg aaaaaccgca aatacaacag ctaacaaata ttgtatcccc agctgtcagg
     4201 ggtgtctttt taaaatttct agaaaaagca gaatcggaga aaatcccgat ccaagtagtt
     4261 attcctgtcg aagtgaaaac aatcccgatt gatctggttg tttttattcg ctgtttatct
     4321 atttttattt ctaacgcatt cgatcatcgt gtagccgatc agagtccgat tacgatcaat
     4381 ctgctggaag aaaaagaggg attacgtttt agtatagcga acaaggcaaa tccgacgaat
     4441 ttgacgctat cggagatggt caaaagagga aaaacctcta aaaaaaatgg cgggttaggt
     4501 ctatacagtg cgaaaaaaat gttggatgtt tacgaaaatg cagaactaaa aatcgaattt
     4561 tcaaaacaga atcactattt ttttgtagaa atgtatctgg catctagaaa gagcaaatca
     4621 gcctactgac ttactgtcaa aggataagct tgaggaaagt ctacacggag atagagacaa
     4681 caacacagca tattcaaaag aaacagaagc gtgatgaccg ttgtcaccct tctgtttctt
     4741 ttgctatgta gttaaacaaa gtagttgaca cttccgctac ttagtattag tacgaaagta
     4801 tacttcatga tactaagtag ataagaagtg aaaagcggaa cccacgatcg tcaaaatgct
     4861 aactgctttg cttacaccag ataaagggaa gagcaatatc gcttatttta ggcgtggaga
     4921 agcaagaaaa tccctacgat cacacaaaaa atgctgaccc agcagttaag agagttagaa
     4981 caagatggca ttgtccatcg aaaagtctat aaccaagtcc cgcctaaagt agagtactcg
     5041 ctcaccgaag aaggaaaatc attaagagag attctagtag cgatgtctgt ttggggagaa
     5101 gaacgtatcg aaaaacaaaa agcctcaggg gaagaagtca cattactgca tacacatggt
     5161 ggctacctaa attactgatt tctatgacat ttattttaaa taaaagaaaa caggagtttt
     5221 tttaaaagca tcatctattt tttatgtaaa aaaatggtat gattaatcaa gtaagaaatg
     5281 attggaagaa ggcaagcaaa tgaatagcat ggaaaaagtt aaccagttta gagatgaacg
     5341 taattggcga caatttcata acgaaaaaga tttggctatt tctatttctt tggaagcatc
     5401 tgaattgtta gaactttttc aatggaaaac gccggaagaa gtaaaagaaa cacaattaga
     5461 acgaatcaaa gaagaactgg cggatgtatt gatctattca tacatgatgg cagacaacct
     5521 tcagctggat ctagatgaga tcattgaaga aaaattgatc aaaaataatt tgaaatatcc
     5581 tgtagaaaaa agcgcaggtg tacgaaaaaa atacacagag ttttagaaat gtgtcattcg
     5641 gctgttggaa agagcaaaag aaaaacagta aaatgagtct ggagggagag aaaatgaaaa
     5701 aaaaaggaaa agcaaaaaga tggctagtca atatcctctt gttcctcttg ttattagtag
     5761 gactagcttt gattttcaat gaacagatca aggattatct tgtcagagag acaggagata
     5821 aatatgctat agcgaatgta acaaaagaag atctgaaaaa gaataacgat aaagatgtca
     5881 gttttgactt tgatgcggta gaaccaatga cgacagaagg ggtcatgagg tcgcagatga
     5941 gaggaacaga tctaccagtg attgctagta tcgcagtccc ttcagtttca atcaatttac
     6001 cgattttcaa aggcttggat aatacgtcac tactttacgg agcaggaaca ttatctccag
     6061 atcaagaaat gggaaaagga aattatgcct tagcaagcca tcgtgcaacg aaccctgaat
     6121 tgttgtttac accgctggaa aatttagaga tgggtgccaa gatctatttg acagatttag
     6181 aaaatgtgta tacatacaaa acatttttta aagaaaaagt tgctcctaca gatacccaat
     6241 tactgaatga agtcgaggaa aaagaaattg tcacactaat tacttgtggc gacatggacg
     6301 ccgtcacgcg actagttgta caaggagaac tggaaagtgt tacaccgata aaagatgcga
     6361 cagatgatat gagatctgct ttcaatctag agacaaaaac attttaggat actgggacat
     6421 aagtcgttac agattaaaaa cagccaaagg atatgaatcg ataaggaaaa accaatttgc
     6481 tgaaaaaaag aggaacgcaa agaggtgcat ctctgatttg gttgttttct agatagactt
     6541 gtgttccagt ttttttattt tttatatgaa aaggcttgca taaataaaaa ttcgatggta
     6601 tgatgatttt gaataagaaa tggattgtta ctgtacggca ggcaaaacca gaattcagct
     6661 aagaaacagt aggcgaattc taggtttttt tatttttctt gagagggcga agcaaaatga
     6721 aaattgataa aattttgaat aacaatgtcg tcatttcgaa aaatggattc ggggaagaag
     6781 tcgtttgtat gggaaaagga ctagcttttc aaaaaaaaga ttggggacga gatttcgcca
     6841 gaagcggtcc aaaaagaatt tattttaaga gattcttttg ctaaaaacca attccagcag
     6901 ctgatggctg atattccggc agaggagatc gaatgggtca aacaagtagt cgaactggct
     6961 gaagataaac taaaagttga attttcgcct aatatttatc tgacattgac cgatcatctt
     7021 cattatgcga tcacacgagc aaaagaaaat atccaactgc ctaatccatt attatttgaa
     7081 acaaaaaaat tttatccgaa agaatatcaa gcagcgaaag aggctctttt gttcgtgaaa
     7141 caaaagacgg gtgtggaact ttctgaggat gaagccggtt ttattgcctt tcattttgtg
     7201 aatagccaac aaggaaacga agacatgcaa gtgacgatga ccgctaccac aatggtaaga
     7261 gatatactga gtatcatcag taaattcttc ggcatcgtgt tcgatgaaga atctttgaat
     7321 tatcagcgta tcattactca tctgcagttt tttgcccagc gttatctcaa aggggaagga
     7381 tctgacgagc aagatgaatt tctctacgca ttagttcaag gaaagtatcc aaaagcgttt
     7441 cattgtgtcg aacggatcaa tgagtatctt cgacaaacgc aaaaacagga aatggggatc
     7501 gcagagcaga tttatttaac gattcatatt caaagagtag taagtgagaa aaaaagcatc
     7561 caatcataag gattgttact gtatggcagg caaaacctgg attgaaaaaa taggttcacg
     7621 aatgtttgtg actgtttttt tcaatctggg tttttatttt ttaaataaaa aagaaagaag
     7681 gaaaaaacaa tggataatca agcagttggt cgtcgtgtat gggaagcggt aggaggacaa
     7741 aagaatgtca aaagtttagt acattgtgct acgcggttgc gattcagatt aaaagatgaa
     7801 tctttagcag atacgcaaaa gttaaaagaa gacccggacg tgatccaagt cgtacaaagt
     7861 ggcggtcagt atcaagtagt gattggcagt aatgtagcag atgtttatca atcgatcgtg
     7921 gatgaggaag gtcttgcagt ttcggaggat ggaaaagaag agtccaaaaa tattttgaat
     7981 cgtctgatcg atattatctc tagtatattt acaccttttc taggggcgat ggcagccgcc
     8041 ggggtattga aaggattctt atcattggca acggtgatgg gctggctgac agctgatagc
     8101 ggtacttatc aaatattgtt tgctgcagca gatggtgtct ttaccttctt acctgtcatg
     8161 cttgctttta cagcagctaa aaagttcaaa gccaaccagt ttttagcagt agcaattgct
     8221 atggcacttg tgtatccagc tatcacagca gttgctggtg cgggagaagc tatcagtttc
     8281 tttgggatcc cagtgattct ttcaccatct ggttatactt cttctgtcat accaatcatt
     8341 ctagccgtat gggttcaaag taaattagag ccattcgtaa aaaaagtgat tccgcaattt
     8401 ctgcaaatga ttttagttcc gcttgtcgtt ttagtagtga tggttccatt aacatttctt
     8461 gctttaggac caatcgggac ggttgccggt aatgctttag gcggtctctt caactcgatt
     8521 tatggattta gtccaatcgt agcaggtcta atcatgggaa gtttatggca agtattcgtg
     8581 atgttcggca tgcattgggg attcgtaccg atcatgtttt tgaatatcga acaatatggg
     8641 tttgatgtat tgatgccaat gcttcttcca gccatcttgg cacaaggtgg ggctgcttta
     8701 gctgtagcat tgcgaacaaa agatacgaaa cttcgagcat tagggatttc ttctacagtg
     8761 acttcgttat ttggaatcac tgaaccaact gtgtatggtg tgacattacc tttgaagaaa
     8821 ccattcattg ccgcttgtat ttctggaggt attggtggag ctattatcgg attttccgga
     8881 gtaaaagctt tctccagcag tttggtcagc ttattgacga ttccgacttt cattaatacg
     8941 gtggatggtg tagagtcaaa tgtgacagta gcagtaatag ctacaggaat tgcttttgtt
     9001 cttgcattcg taggtacatt gattttagga tttgacgaac aaacacaaga caatcaatta
     9061 gaaaacaaac atgcgaatgc aggagaaccg attacttcag cacggcatac cttaaaaagt
     9121 cctttaacgg gtaaagtact gccattgagt gaagtaccag accaagtttt ttcttctggc
     9181 gtgatgggaa aaggtatcgc tattgatcca gaagtaggag aactagttgc acctgcagac
     9241 ggagagatca cgactatttt tccaactgga catgctgtag ggatcacaac gactgacgga
     9301 gcggagattt tgattcatat cgggatggat acagtagaat taaatgggaa tggctttgag
     9361 atcttagtca aacaagggga tctcgtcaaa gcaggagatt tattgattcg ttttgacatc
     9421 gaagcaatta gagcagctgg ctatagcgta atcactccag ttgtcattac gaatactgat
     9481 gcatttgccg atatacttga attagaccaa aaagagatta ttgcaaacga agatgttctg
     9541 gcaattgtaa aataaggagg aaatcaggat gcaatcacgt ttttcagaaa aatttttatg
     9601 gggtggagca actgctgcca aatcaattag aaggggctta tgatcgagac ggaaaaggac
     9661 tatccgttgc agatgctatg cctggaggta agcagcgctt tgcgattatc ggcagtgaag
     9721 aatttgactg gacgattgat caagaaaaat atatttaccc gaatcatcga ggaatcgatc
     9781 attacgatcg tttcaaagaa gatcttgcct tgtttgcgga aatgggattc aaatgttatc
     9841 gtttttcgat tgcctggaca cgaatttttc caaatggaga cgaaggtact cctaacgaag
     9901 cgggattaga attttatgat cagctgattg atgagtgctt aaaatatgat attgaacctg
     9961 tgatcacgat ttctcattac gaaatgcctc ttcatttggc aaaagaatac ggtggctgga
    10021 aaaatcgaaa actgatcgac ttctatgaac gatttgctca gacagtatta gagagataca
    10081 gcagtaaagt caaatattgg atgactttca atgaaatcaa ttcggccttt cactttccag
    10141 ctttaagtca aggattagta aaaagcaatg gagcaggaga gtaccaaaat attttccaag
    10201 catggcataa tcaattcgtt gcaagtagca aagccgtaaa aatcggccac gaattgcgtt
    10261 cggatatcca aatcggctgc atgattatct atgcaacaac ttacagcatc gatgccaatc
    10321 cagtcaatca ggcagcaaca atgatccaaa accaagaatt caattttttc tgcacggatg
    10381 tccaagtacg tggagaatac cctgcataca cagcgcgtac ccataaaaaa tatggagtcg
    10441 atccggaaaa attagagcaa acggaaaaag acttccagtt gctaaaagaa tatccagtgg
    10501 actacatcgg atttagttat tatatgtcta cggcaatcaa tgagactgat ccacaagcag
    10561 caacttcaga agggaacttg ctgggaggag taaaaaatcc gtttcttgag gcaagtgaat
    10621 ggggctggca gatcgatcca gaagggctga gaatcgcatt gaatgaatta tacaatcgtt
    10681 accagaaacc attattcatt gttgaaaacg gtcttggagc cattgatcat atggaagagg
    10741 atggcacgat tattgatgat tatcggatcg attatttacg tcgtcatatc gaagcgatgg
    10801 ctaatgcagt agcagacggt gtagatttga tgggctatac gccttgggga tgtatcgatc
    10861 ttgtcagtgc atcaacagga gaaatgagta aacgttacgg ctttatctat gtggatctag
    10921 acgatgaagg aaatgggaca ctgaatcgat caaagaaaaa atcttttgat tggtataaag
    10981 aagtaattgc ctcaaatggc gtaaacttgt aattaaagca gctgaatgaa aaagaacaca
    11041 cttctcacat gtgatttgtg ttcttttttt attttttatg tgctattctt ttagtaatag
    11101 taaagcaaag ggtgacgtta tgaaaaggac acgtgtacta tacttggaag tcgcagataa
    11161 aattaaagaa gatattttct caggaaaata tccagtcggt tcgatgttgc cgacagaaag
    11221 tgaattagaa gaactgtttc aagtcagcaa aatcactgtc cgaaaggcaa tcgaactgct
    11281 ggcatcagat gaatatgtcg caaagaaaag tggtcgtggg acgacggttc taagcaatcg
    11341 tccttacaat cgattatcca aagcggcaag ctttacgcaa atcttggaga actcccgata
    11401 tgaagtccgg aaagaaacgc tggatttgca attggtccat ataaagaagg aagatccttt
    11461 gttttccttt ttcggtgagc aagctgtttg ttttaagcgc ttatattatt tgaacaatca
    11521 gccttatatt tattttgttc attatcttcc acaagaaatg atgcaattca gcagagaaga
    11581 atttggcaaa gaatctttgt atcgtttgct gacgaaaaaa ggatatacta ttgactcatt
    11641 ttctgatgat ttctcggcag tatttttaac agaagaagaa caaggaattc tgaaaacaga
    11701 cgcacagatc ggcatcaaac ggatacggaa atcgtctacg caaattgggg aaatgattga
    11761 atattcggag gcggtctacc atacggagct gcatccttac catattgatt atgaaacata
    11821 aataaaaaaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaaacaa
    11881 aaatagcttc tcatattttt cgtttggtta ggcttattac cgcagataca cggctgtttc
    11941 tggattacca tttattctgg ataagggggt gtggcacgat tttcagaagg aatctatgaa
    12001 ccaatcactg tattgatttt agcttcgatg gtaaccccat tcggcttgac gatcgcttat
    12061 ttcttaggga aaatcattcg taaaaatata ctcaatcgtc aagaaatcga tacattgaag
    12121 accgcttttc ctatggggat ctgtcagatc acagagggat gtttccctat cgtattgaac
    12181 gacttggcac gcaatgtcat agcaacggga gtcggtggga cagtaggtgg cggattaagc
    12241 atgttttggg gcgcagatag ccgtattccg gcatcgggaa tgtttgcagt cgctacgatg
    12301 accagaccat gggcattcat tggtgcattg ttagctggtt cttttgtcac aggaataacc
    12361 attttattat tgaaaaaacc agtagatccg aatgcagaaa tcatccaaga agaaaaagag
    12421 gaagaagaca tatcttggga tgatttgaca attagttagg agaggcagaa tggattacaa
    12481 gaaaaaagta caatagatgt accttgagac aggaatggta tgaaagaatc agagttagaa
    12541 agaatcgaat atacagattt tggtttagga gcgatcgaaa ctgtccagag catcggcacc
    12601 ctccttgaaa tgacgatgaa ggaaaaatga gaacctttcg ttgtcgaaag ggtctggtat
    12661 accttatgtc gaaggaaagg aaacaaaaaa actttcctgt actattccaa aaaggaaaga
    12721 aagttattat acagtaaaaa aagaaattat tcttcatgct agagatcagt acacgttcga
    12781 gcccaatatc aaacactagt tccaggcagg cgcaacaggt gcggttatca ctgaattttc
    12841 ttccagcagt gacgattcaa gtgatatttt tacaaatcca gctatttatc gttaacaaaa
    12901 agatttttag gagaagctga tgaacaaaaa tgatcaaatt ttgatcgttt agttcgtcgg
    12961 cttttttatt tagagaaaca tcatttatca gtgaaacata acacgagaac aaaatgattt
    13021 tttcgttaat aaaagaaaca agtatttgtt gtttaaaata atacacgtta ttggcatata
    13081 ggacgaaatc ccagtatctt ctataagtaa gtcatttcat atcgatgaaa acacgttatt
    13141 tatttttgtt ttatctataa aatggctgaa aaatgatttt tttctaaata ctatatatag
    13201 tggcgtctat cctatatacc actaaaaaac tacaaaatct agtcttttat tttaaaaaaa
    13261 cacgtgtaga atgaagatag acttttgagt tagggagtgt ttttttatga aacttactgt
    13321 tttttgcggt tcccgttttg gtaataaaga aagttacaaa tttattgcgc aaacgttagg
    13381 aaaatacatg gcacaagaag aaatcgaact ggtttacggt ggttcatact ccgggattat
    13441 gggagtgatt agtaaaacag tactggaaaa taacggaaaa gtcacaggta tctatccgaa
    13501 tgggcttttt gaaactgaat tgcctggaaa agatgttact acatttattc ctacagaaac
    13561 gatcgatgaa agaaaggtat tattatttga aaagggagat gctgtcctcg ttttccctgg
    13621 aggtctaggt acattggagg aattctcaca acttctttct tggatagcaa tcggtctgac
    13681 gcccgacaag ccaatcggaa tattgaatat tggcggttat tacagcggct tgcaacaatt
    13741 attagaaact tttgcaaaag aggattttat ggataaaaaa tggttggatc aagtaatctt
    13801 ttccaacaat ccattggaac tggtcaatga attacgagca gtatctatta aaaatcagtt
    13861 attattgaag gaggcaaaat aatgagtcaa atatatttag caggaccatt tttttcagag
    13921 gagcaaatcg atcgagtaag tcgtatcgaa aaagcgttgg aggaaaacaa aacagtcaca
    13981 agtttctact ctccacgtca tcaccaagaa agcaattatg aactattcag cgctggatgg
    14041 gcgcaggaag tatacgaaaa agatatggaa gaactgacaa atgcagaatt tgttgttgct
    14101 atccttgact ttgagcatca aacaatcgat ccaggaacgg cttacgaatt aggtgtggca
    14161 actatgttga aaaaaccgat gatcattgta caagaagaga cggtacctac gaacttgatg
    14221 attacacaaa gtctccatac gtatttaaaa tcagaccaag ctgtacgtga atatgatttt
    14281 gaaacattgc ctgttgaaac ttacgtaggc gagtacttat agaagaggaa gggttgtatg
    14341 tcagtgattt tgatttcagg aacgattggt gcaggtaaga gcagtttgac ggatatgctt
    14401 gcaaaagaga ttgattctaa accattttat gaaaatgtcg aagataacga agtattgccg
    14461 ctcttttatt caaatcctga gcagtacgct tttttattgc aaatcttctt tttgaacaag
    14521 cgatttttag caatgaaaaa tgctttagtg aacgatgaca atgtgctaga ccgatccatc
    14581 tatgaagata gcctgttgtt ccatctaaac gctgatttag gtcgggtaac ggatatcgaa
    14641 gtacagcagt acgatagctt attagatacg atgctaaacg agttagatga tgttgctcca
    14701 aaaaaacggc ctgatttgat ggtccatatc aaagtttctt tggacacgat gctagaacgt
    14761 atcaaaaaac gtgggcgtga ctatgaacag ctagaaagcg atgagacgtt atatacctat
    14821 tatgaaacgt tgaacacccg ctataatcaa tggtatgaag attttgatgt atgtcctaaa
    14881 atacaagtgg atggggataa attcgatttt gtagaaaatc cagaagatgc aaaaaaggtg
    14941 atccgtcaga tccaagaaaa attagctgaa ttggaaggaa agcctgctgg aaaatatttt
    15001 acggataacc agcatgcaaa aggtcaagaa ttaggctaaa aataaaaaac caaacgacgg
    15061 gaaagaaaaa tt
//
LOCUS       DAZKCH010000065        14578 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000065 DAZKCH010000000
VERSION     DAZKCH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.065"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            134..1030
                     /locus_tag="ACG84X_002087"
     CDS             134..1030
                     /locus_tag="ACG84X_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFP9127926.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1180..2121)
                     /locus_tag="ACG84X_002088"
     CDS             complement(1180..2121)
                     /locus_tag="ACG84X_002088"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFP9127927.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2247..3368
                     /locus_tag="ACG84X_002089"
     CDS             2247..3368
                     /locus_tag="ACG84X_002089"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFP9127928.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3626..5128
                     /gene="eat(A)"
                     /locus_tag="ACG84X_002090"
     CDS             3626..5128
                     /gene="eat(A)"
                     /locus_tag="ACG84X_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFP9127929.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5195..5722
                     /locus_tag="ACG84X_002091"
     CDS             5195..5722
                     /locus_tag="ACG84X_002091"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFP9127930.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            5933..6994
                     /locus_tag="ACG84X_002092"
     CDS             5933..6994
                     /locus_tag="ACG84X_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFP9127931.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6997..7893
                     /gene="murQ"
                     /locus_tag="ACG84X_002093"
     CDS             6997..7893
                     /gene="murQ"
                     /locus_tag="ACG84X_002093"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFP9127932.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7907..9889
                     /locus_tag="ACG84X_002094"
     CDS             7907..9889
                     /locus_tag="ACG84X_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFP9127933.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9954..10400)
                     /gene="nrdI"
                     /locus_tag="ACG84X_002095"
     CDS             complement(9954..10400)
                     /gene="nrdI"
                     /locus_tag="ACG84X_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFP9127934.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            10611..12035
                     /locus_tag="ACG84X_002096"
     CDS             10611..12035
                     /locus_tag="ACG84X_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFP9127935.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(12216..12989)
                     /locus_tag="ACG84X_002097"
     CDS             complement(12216..12989)
                     /locus_tag="ACG84X_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFP9127936.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12986..13891)
                     /locus_tag="ACG84X_002098"
     CDS             complement(12986..13891)
                     /locus_tag="ACG84X_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127937.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(14045..14365)
                     /locus_tag="ACG84X_002099"
     CDS             complement(14045..14365)
                     /locus_tag="ACG84X_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFP9127938.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         4652 a         2603 c         3090 g         4233 t
ORIGIN      
        1 agaatgattt atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa
       61 acgttttact ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag
      121 tgaggcggaa aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta
      181 ttttttgcct tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga
      241 attcattaaa tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta
      301 tggatttgat atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt
      361 atttttttgg aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga
      421 accggcaatc gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa
      481 acataatagt tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga
      541 tctatttttt ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga
      601 atttataaaa agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca
      661 acctggatat cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct
      721 ggaactgttg cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt
      781 tcaaaagaaa ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga
      841 aaatattttt ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc
      901 atttaagcca atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg
      961 atttatcact aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga
     1021 aaacaaataa aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc
     1081 ttatggcatc atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga
     1141 accagctgct gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc
     1201 ttcttttgca tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt
     1261 ttgtcctttt cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt
     1321 gatcaggtct tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga
     1381 agcaatatgt tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga
     1441 agcaaattca gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc
     1501 agcaatatta caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt
     1561 tcgccaaatg gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa
     1621 gacttctaca actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat
     1681 ttctccatca cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt
     1741 gatcccaaat aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa
     1801 tccatttagt aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa
     1861 catatcatct aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct
     1921 ttcgatgatt tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa
     1981 gtcagcaatc aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa
     2041 gaggacctca tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc
     2101 cccagctatt gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta
     2161 tatagaaaaa tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt
     2221 acttaagaag aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag
     2281 gaagtgcttc ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag
     2341 gaagaaaaat caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt
     2401 acgcgctcag gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa
     2461 aaatcagcta tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac
     2521 aagcattggg gttagatcta cttgataaac caacggatca aactatccga cttgcttcca
     2581 gttatgcctt aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg
     2641 tcactttagg aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg
     2701 cttctttaga agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg
     2761 atcgaagaaa cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc
     2821 catatacagg tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata
     2881 cgacgctagc tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct
     2941 gggaggtgga tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc
     3001 tttttttgtt gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat
     3061 tggaaaaaaa gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc
     3121 aaacgatcca cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac
     3181 caataatcgc tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc
     3241 caattgtctt aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc
     3301 aaacattaga aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc
     3361 cgaagtagtt gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt
     3421 gagggatccg tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct
     3481 tgtggagaca aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg
     3541 ggtctttttg tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg
     3601 gtcttttttt acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg
     3661 ctacgacagc caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg
     3721 gaaactagga cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca
     3781 aaacaaacta ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca
     3841 acagacaaaa gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga
     3901 gatatgggaa atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag
     3961 agaattcagc acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt
     4021 ggatgacact catttcccgt taatcgatga accaacgaat catttggata tctctggtag
     4081 aaaacaagta gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga
     4141 ccggggattt atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga
     4201 actttatcaa gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga
     4261 aatggctcaa aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga
     4321 aaaagccgaa tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat
     4381 cgatactgaa tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat
     4441 gaaacgatcc aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact
     4501 attaaaagat atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa
     4561 gcgactttta agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat
     4621 tcattttaca atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa
     4681 gtcatccatt atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata
     4741 ccagccaaaa catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac
     4801 gttggcggaa tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg
     4861 aaagcttggg atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca
     4921 acggaaaaaa gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga
     4981 tgaaccattg aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa
     5041 cgtgaaacct gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac
     5101 tgagattatt tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt
     5161 taaggggaac tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga
     5221 aacaacttgg aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa
     5281 aggacagatg caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac
     5341 gaaaatcatc cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg
     5401 tctcagcttg ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga
     5461 tggactgcca agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt
     5521 cccaaatggg gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg
     5581 catcgaagac gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat
     5641 caatgcttat tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac
     5701 agaattggtt tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc
     5761 actgcttttg cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact
     5821 caacctttag aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag
     5881 atatatactc tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg
     5941 cttttcaata tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat
     6001 ggcatccaat ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc
     6061 ggcatatcaa aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt
     6121 gatggtcgat atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac
     6181 gcctttgaaa gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca
     6241 gattgccgac tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa
     6301 agatatcgat gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa
     6361 ttattatcca cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg
     6421 gctcaaaatt caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg
     6481 cccactatat caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg
     6541 cgctctagat ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc
     6601 agaaaacgtt caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac
     6661 ggaacctgta gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga
     6721 cgatgcaaga gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc
     6781 agcaagaaat acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt
     6841 gcgctatatg ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa
     6901 tgtagtagct aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat
     6961 gaactatcaa tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac
     7021 ctaacaacgg aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa
     7081 gccgttcaac taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg
     7141 acaagtatcg aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg
     7201 atttatatgg gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta
     7261 ccgacattcg gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca
     7321 atgactgtag ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc
     7381 aagctgaatt tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca
     7441 tatgtgatcg gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct
     7501 tgcaataaac aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt
     7561 ccagaatttt tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg
     7621 aatatgattt ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc
     7681 gatgtcaaac caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg
     7741 acagaagctg attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag
     7801 ctggctatcg tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct
     7861 gaagcaaacg gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga
     7921 actgactttg gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt
     7981 agaaagcatt gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt
     8041 aaatgtctct gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct
     8101 tcaagtcatc atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc
     8161 aggcgtgaaa ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc
     8221 atctggaaaa gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa
     8281 acaaaaacca tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat
     8341 gattcctgca tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt
     8401 agtcacagcc ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat
     8461 cttgaaaaac gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt
     8521 ttttggtgca acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat
     8581 gaatccggaa gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg
     8641 tgggatccta ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca
     8701 taaagtagta cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat
     8761 cggtctgatt gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt
     8821 cggtgggatc aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac
     8881 attattcttg ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca
     8941 aatgattgat gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg
     9001 acaagtgggt gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga
     9061 aatgatcaaa ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg
     9121 agtaacatta cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg
     9181 ggcagtgatc ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc
     9241 tttgatccca ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc
     9301 ttatgctggt ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa
     9361 agaagaatta gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca
     9421 aacttcagct gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt
     9481 agataaagca agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga
     9541 accagaaaac ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac
     9601 gaaacacgct attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat
     9661 caacacagtt gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt
     9721 gacacctgat acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga
     9781 aacatccatg atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa
     9841 aacaggtaaa gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa
     9901 caatagaaac gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta
     9961 ttgttttctg ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca
    10021 taatctgcca agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac
    10081 tgattattga agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct
    10141 tcatgttcca gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa
    10201 ccatttccgc cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta
    10261 aaatcactat tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca
    10321 tgcatttttt cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc
    10381 gatatatata aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt
    10441 tttaagtttt ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga
    10501 aaaaagccgg tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa
    10561 ggtttgttat actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag
    10621 agcaacagaa aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga
    10681 ttggaggtgg cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta
    10741 ttttcagttg ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata
    10801 tcaataaaaa acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg
    10861 gccgtttcgc tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg
    10921 tagcttttgc aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg
    10981 ggcaaaatct ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag
    11041 tgaatcgggg agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag
    11101 tgccattatt tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg
    11161 ataacttttc tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc
    11221 aagtattgag ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg
    11281 tcgtaggttc acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat
    11341 tcggcttgat tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga
    11401 atcagctgca aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg
    11461 gtaaatgggg agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc
    11521 tctcatggac gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc
    11581 ctaaagcatg gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga
    11641 cgttatgtac gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg
    11701 cttacacact tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa
    11761 tgaaactttc ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg
    11821 cctttcaagt atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc
    11881 ttttcttgcc aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac
    11941 aacatatcca cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa
    12001 tggttttatt tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag
    12061 gttgtgagcc tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg
    12121 tcacagctcc tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg
    12181 aacgtctctt tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg
    12241 agatatccta atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta
    12301 gtagaaagat gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc
    12361 aacatactga tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata
    12421 ccagatatga ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa
    12481 ctattgataa agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa
    12541 ctacccaaag tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc
    12601 gtgaaggaaa tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa
    12661 aggtataaat aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct
    12721 cgagaatact ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg
    12781 atcgtgcttg cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga
    12841 gcagtcattt caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct
    12901 atgagcaaaa caactaatag aacagataaa acagcagttg actttttctt gatcaattta
    12961 aataattctt gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa
    13021 tttccaatag agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat
    13081 tttgtgcaga caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct
    13141 tgattttatc aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta
    13201 gatcatttgt tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg
    13261 tacattgttt gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa
    13321 gctcgctgag taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa
    13381 tgatttttcg cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa
    13441 taacgataga cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca
    13501 acgagtagga tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag
    13561 tgtcgatagc agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta
    13621 agaatggata gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac
    13681 tagagggaga aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc
    13741 ctaaaatagc tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga
    13801 ttttgccagg ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct
    13861 tggataattc ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta
    13921 caagcataca cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt
    13981 cataaaaaaa ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa
    14041 gtgtctagtg gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa
    14101 agaaccaagt ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac
    14161 caactgcgcc aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg
    14221 cctttgacaa aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga
    14281 ttttagaaaa accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg
    14341 ctatgattaa ttccatccat gccatactta cattcctcct taactataaa aaaatacaca
    14401 aaaagaggaa aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc
    14461 ggtggcagat tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct
    14521 catacttttt agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaag
//
LOCUS       DAZKCH010000066        14549 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000066 DAZKCH010000000
VERSION     DAZKCH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.066"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..816
                     /locus_tag="ACG84X_002100"
     CDS             4..816
                     /locus_tag="ACG84X_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFP9127939.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="ACG84X_002101"
     CDS             813..1613
                     /locus_tag="ACG84X_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFP9127940.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="ACG84X_002102"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="ACG84X_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFP9127941.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="ACG84X_002103"
     CDS             3110..4819
                     /locus_tag="ACG84X_002103"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFP9127942.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9389
                     /locus_tag="ACG84X_002104"
     CDS             5031..9389
                     /locus_tag="ACG84X_002104"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFP9127943.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9534..10007
                     /gene="rimP"
                     /locus_tag="ACG84X_002105"
     CDS             9534..10007
                     /gene="rimP"
                     /locus_tag="ACG84X_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFP9127944.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10030..11205
                     /gene="nusA"
                     /locus_tag="ACG84X_002106"
     CDS             10030..11205
                     /gene="nusA"
                     /locus_tag="ACG84X_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFP9127945.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11227..11520
                     /locus_tag="ACG84X_002107"
     CDS             11227..11520
                     /locus_tag="ACG84X_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFP9127946.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11517..11828
                     /locus_tag="ACG84X_002108"
     CDS             11517..11828
                     /locus_tag="ACG84X_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFP9127947.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11841..14147
                     /gene="infB"
                     /locus_tag="ACG84X_002109"
     CDS             11841..14147
                     /gene="infB"
                     /locus_tag="ACG84X_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFP9127948.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14174..14521
                     /gene="rbfA"
                     /locus_tag="ACG84X_002110"
     CDS             14174..14521
                     /gene="rbfA"
                     /locus_tag="ACG84X_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFP9127949.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4959 a         2583 c         3238 g         3769 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgagtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccacatccag ctaggacgaa
     5701 atattccagc cgatgaacca acgacaccaa tgatcagtat cgttgaagaa gaacgaagag
     5761 tcacacttga ggggtacgta ttcgacaaag aagtcagaga actacgttca aaacgcaaga
     5821 tcttgacttt gaaaatcaca gattatactt catcatttat cgtcaaaaaa ttctcgaacg
     5881 gcgaaaaaga tgaacaagta tttgatgcga tcagtgtcgg tagctggtta aaggtacgag
     5941 gaagtattca agaagatacg tttgtccgtg atttggtcat gaatgcgcaa gatatcatag
     6001 aagtcaaaca tacacctcgc aaagattatg ctcctgaagg ggaaaaacga gtagagcttc
     6061 atgttcatag caatatgagt acgatggatg caacaaacag catctctgat cttgtggcac
     6121 aagcagggaa atggggacac cgagctatcg ccattacaga ccacggtggt gcgcaagcct
     6181 ttccggaagc acatagtgct ggaaaaaaag caggtgtgaa aatcttatac ggcgtggaag
     6241 cgaatgtcgt agatgatggt gtcccaattg cttataatga tgcacatgaa gcattgagtg
     6301 aagccacata tgtcgtattt gacgtggaaa cgacaggatt gtctgcagta tatgacacga
     6361 tcatcgagct agccgcagtc aaaatgtata aaggaaatgt gatcgaaagc tttgatgaat
     6421 ttatcgatcc aggacatcct ttgtcacgaa caacggtaga tctgactggt atcacggatg
     6481 gaatggttcg aggatcaaag tcggaagaag aagtattgcg gatgttcctt gaattttcaa
     6541 aagatacaat tttggtagcc cacaacgcgg cttttgatat ggggttcttg aatactagct
     6601 acgcaaggta tggtattcct gaagcggcca atccagtcat tgatacgttg gaattagcta
     6661 gatatctgta tcctcaattc aaacgtttcg gattaggtgt gttatctaaa aaatttggtg
     6721 tcagcttgga acagcatcac cgagcaatct atgatgctga agcaactggt cacttagcat
     6781 ggatctttgt gaaagaggca atggacaatc ataacatgct ttatcatgat cagctaaatg
     6841 agcatatcgg agaaggagat tcttacaaaa gggctcgacc tttccatgta acgattttag
     6901 caaaaaatca ggcaggactg aaagatttgt tcaaactgat ttcaatgtcg aatgtcgaat
     6961 acttcgaacg cgtcccacga ataccacgct cccaattgaa aaagatgcgt gaaaatctat
     7021 tgatcggctc agcttgtgat aagggagaaa tattcgaagc catgatgcaa aaaggggtag
     7081 aagaggcaag aaaccgagca aaattctacg attatattga agttatgcca aaagcggtct
     7141 atgcgccttt gatcgagcaa gaattggtaa aaaatgaaca tgatttggaa gaaattatcc
     7201 aaaatttggt agaaatcgga aaaagtttgg ataaaatcgt tgttgcaaca ggtaatgtac
     7261 attatctgaa cgaagaagat gccatttacc gaaaaatttt gatcaattct atgggcggag
     7321 cgaatccgtt gaatcgtcat agtttgccgg atgtccattt ccgaacaacc gatgagatgc
     7381 taactgcatt tcacttttta ggggaagaaa cagcgaaaga gatcgtagta gaaaatacga
     7441 ataaaatcgc agatatctgc gaagaagtga ttccagtcaa agatgaactt tatacaccga
     7501 agattccagg ttcagaagat gaaatatcag aattgagtta cacaaaagca aaacaaatgt
     7561 acggagatcc gttacctgag atcattcaaa aacgattaaa aaaagagttg aattctatta
     7621 atggtaatgg cttctcggtt atttatctga tcgcccaaaa actagtgcat aaaagtaatg
     7681 aagatggcta tctagtaggt tcacgtggct ctgttggctc tagctttgtt gcgacgatga
     7741 caggaatcac tgaagttaat ccgttagccc ctcattatta ttgtccagag tgccaatatt
     7801 ccgagttttt tgaagatggt acgtatggtt ctggatttga catgccagaa aaacaatgtc
     7861 caaaatgtgg tgcacgctta aacaaagacg gtcatgatat tccatttgag acatttttag
     7921 gattccatgg agacaaagtg cccgatattg atttgaactt ctcaggtgat tatcaagcag
     7981 aagcccataa ctatacgaaa gtattgtttg gcgaagacta tgtttaccgt gccggaacga
     8041 ttggtacagt cgccgacaaa acagcatatg gctatgtaaa aggatacgaa agggacaata
     8101 atctgcagtt tcgaagtgca gaagtcgaca gattagcaaa aggcgctact ggagtcaaac
     8161 ggacaaccgg ccagcatcca ggggggatca tcgttattcc cgattatatg gatgtctatg
     8221 attttacgcc gatccaatat ccagcagacg atcaaaattc ggaatggaaa acgactcatt
     8281 ttgattttca ctcgattcac gataatgtat tgaaattaga tattctaggg catgatgacc
     8341 caactgttat tcggatgctt caagatttat cagggatcga tccacaaacg atccctacgg
     8401 atgacccgga agtgatgcgg atatttgccg gtcctgaagt acttggagta agtcaggaac
     8461 aaatttattc caaaacaggg acattaggta ttccagaatt cggcactcgt tttgttcgag
     8521 ggatgctaga agaaacgcat cctacaactt ttgcagaact actgcaaatt tccggactat
     8581 ctcatggtac agacgtatgg ttaggaaatg cggaagaatt gattcgacga ggagatgcga
     8641 cactggcgga agtaatcggc tgtcgtgatg atattatggt ttatttgatc catgctggat
     8701 tagatagcgg gatggcattt aaaatcatgg aaactgttcg taaaggacaa tggaacaaga
     8761 tccctgatga attgcgagaa acctatctat cggcgatgaa agaaaataat gtgcccgact
     8821 ggtatatcga ttcttgttca aaaatcaaat atatgtttcc gaaagcccat gctgcagctt
     8881 acgtattgat ggctcttcgt gtcgcttatt tcaaggttta tttccctatt ttgtattact
     8941 gtgcatactt ttctgtacgt gcagacgact ttgatctagt ctccatgtgc aaaggaaaag
     9001 atgctgtgaa acaagcaatg aaagaaatca cggacaaagg attagatgct tccgtaaaag
     9061 aaaagaatca actgacagtg ctggagttag ccaatgaaat gctggaacga ggattcaaat
     9121 ttggaatgat tgatttgtat aaatcggatg ccgttaactt tgttattgaa ggtgatacgt
     9181 tgatcgcacc atttagagct gtcccaagtt tgggaaccaa cgtggcaaaa caaatcgttg
     9241 aagcaagaaa agacggtcca tttttatcca aagaagatct tgccacccgc ggtaaagttt
     9301 caaaaacatt gatcgaatat atgaacgaca atggcgtatt gaaagatcta ccagatgaaa
     9361 atcaattatc gttattcgat atgctataag catctgtttt cctgtctgct tgtaatttta
     9421 agcagagtat ggtatagttc ttataggtaa tgatactaac tgtgagtgag cggatttttc
     9481 gctcactctt tttaatggaa ttacgcactt aattttttaa ggaggcgaaa cttttgagta
     9541 gcgtcgttga aacagtcaca gaaatggtga caccgatttt agatgaacaa aattttgaac
     9601 ttgtcgaagt cgaatttgta aaagaaggaa aaagctggtt cttacgagta tttattgaca
     9661 aagaaggcgg tatcgatatc gaagaatgcg cctttgtcag tgagaaactg agtgaaaaac
     9721 ttgatgcagc agatccagat ccgattcctc aagcttattt cctggaggta tcctccccgg
     9781 gagcagagcg gccattgaaa aaagaaagcg actatgaaaa ggcacttggt gattatgtcc
     9841 atgtctcctt ataccaacca gtagatggcg aaaaacaata tgaaggattt cttcaatcat
     9901 ttgatgctga acagcttaca ttgaaaatac gcataaaaac acgagaaaaa gaattgactt
     9961 ttgaccgaaa aaatattgca aaagctcgct tagctatcca attttaatca cggagaggaa
    10021 tcagaaaaaa tgagtaaaga aatgttaaat gcgttagacg ctttagaagc tgaaaaaggg
    10081 atctcaaaag aaatcgtgat cgatgcttta gaagcagcat tggtttctgc atacaaacgt
    10141 cactatggcc aagcacaaaa cgtcgaagtg gaatttgatc agaaaaaagg aaagatccat
    10201 gtctatgcgg taaaagaagt aacggaagaa gtgatggatt cacagttgga agtctcattg
    10261 aaagatgcac ttttaatcaa tccagcatat gagatcggtg atacgatccg ttttgaagta
    10321 acaccaaaag attttgggcg gatcgctgcg caaacggcta aacaagttat tttacagcgt
    10381 gtacgtgaag cagaaagaac gattatttat aacgaattca gtgcttatga aaaagacatc
    10441 atgcaaggaa tcgtcgaacg ccaggataaa cgttatattt atgtcaatct tggtaaaatt
    10501 gaggcagttc tttctaaaca agatcaaatg ccaaatgaat tttatcaacc acatgatcga
    10561 atcaaagttt atgtttcccg agtagaaaat acgtctaaag gtccgcaagt atttgttagc
    10621 cgcagccatc cagacctatt gcgccgctta tttgagcaag aagtaccaga agtctatgat
    10681 ggaatcgttg aaattgtcag catcgcccgt gaagctggcg atcgttcaaa agtggcagtt
    10741 cgctcaaatg atccaaatat cgatgcagtc ggtacatgtg tcgggccaaa gggacaacga
    10801 gttcaagcaa tcgtcaatga attaaaaggc gaaaacatgg atatcgtcga atggaatgaa
    10861 gatccagctg tattcattgc aaatgcattg aatcctgcac aagtcatgga tgtgatcttc
    10921 gatgagacaa atccaaaggc ctgcacagtt gtcgttccag actaccaatt atcgctagca
    10981 atcggtaaac gcggacaaaa cgcacgttta gctgctaaat tgactaacca taaaatcgat
    11041 atcaaatcag aatctgacat gacggaattt tatgaaaatc aagaacaaca aaaagaaaca
    11101 gaagaactgc atgatgaagc aatcgttcag tcagatttaa cagacgatga atatgaaaca
    11161 attgcattca acaatgaaac ggtcgaagaa aaaccagaag cttaacttta gtaaggaggc
    11221 aaagagatga aacaaaggaa aattccttta cgcaaatccg tggtttcagg tgaaatgaaa
    11281 cctaaaaaag agatggtccg aatcacccgt tcaaaagaag gggaagtatc gatcgatcca
    11341 actggaaaaa tgcctggacg aggagcgtat gtctcacttg agccggaaga agtacaacaa
    11401 gcttgggata aaaaaattct cgatcgagta ctcgaaacaa cattaacaga tgagttttat
    11461 caagaacttc ttgactatgt cactcaccaa aaagcacgta aagagttatt tggaaaatga
    11521 atacagttaa tcggcaaaaa gccatgaatc tcatcggtct agcgatgcgc gcgggaaaac
    11581 taatcacggg tgaagaactg accattgctg aaatccgcaa acaaaaagca aaattggtgt
    11641 ttgtggcaac cgatgcaagc gagaatacaa gaaaaaagat aaaagataag agttcatatt
    11701 atgaagttcc ttgctttgag ctattttctg aagcagaaat cacgcagatg atcggaaaac
    11761 ctcgcaaggt attcggaata atggatgccg gatttgcgaa gaagaccaag gagctaattg
    11821 aaggttagga aggtgattgc atgggcaaca aaagaatcta tgaattagca aaagaactca
    11881 aaaaatctag taaagacgtc gtggaaaaag cacaacaact tggcatcgat gtgaaaaacc
    11941 atatgggtgc gattactagc aatgatgaga agaaattgca acaagcgttc aaaaacccaa
    12001 gcacgaaaca acaagctgca caacaagcaa gcagaaaacc agccaatcaa cagccgaacg
    12061 atcaacgtaa aaaagaaaca acgaacaatc aacaaaaaaa taaaaataac cgcagttatc
    12121 aagatcgcgg tcaagggagc ggtcaagtga atcaaggaaa aaaaccaaca acaaaccaaa
    12181 ataatacggg aaataccagc agccaaaatc gtcaaggaac gagccaaggc ggcaatcaaa
    12241 accgtactaa caataacaac aaaccaaaca ataacaatcg cggcaaattt aataataata
    12301 accgtaatcg ttataataaa aaaggtaaaa aaggcaaaca gcaacaatca actaaaccag
    12361 ctgtaccacc acgcaaattc cgtgaattgc cagatgtatt agagtatact gaaggtatga
    12421 acgtagcaga tattgcgaaa aaaattcatc gtgagccagc agaaatcatt aaaaaattat
    12481 ttatgcttgg tgtcatggtc aatcaaaacc aagcactgga taaagatacg attgaactgt
    12541 tagcgacgga ctatggcatg gaaccacaag aaaaagtcca agttgacatt gctgatatcg
    12601 ataaattctt cgaggcagaa gaagtcgatc cagataaatt agtctcacgt ccgccagtcg
    12661 taacgattat gggacacgta gaccatggga aaacaacttt attggataca ttacgccatt
    12721 cacgtgtaac aagcggcgaa gccggcggaa tcacacagca tatcggtgcc taccagatcg
    12781 atattgatgg taaaccaatc actttcttgg atacaccagg acatgcggcc tttacaagta
    12841 tgcgtgcacg tggagcaagt atcacagata tcacgatctt agttgttgct gcagatgatg
    12901 gcgtcatgcc acaaacagtt gaagcaatca accatgccaa agctgcaggc gttccaatca
    12961 tcgtcgctgt aaataaaatt gataaaccag gtgcaaaccc tcaacatgtt atgcaagaat
    13021 taagtgagta tgagttaatt cctgaagcat ggggtggaga aacgatcttt gttgagatct
    13081 cagcgaaatt cggccaaaac atcgaagaat tgctggaaat gatcctgtta gtcgcagaag
    13141 tagaagattt aaaagcagat ccaacacaac gcgcaatcgg aacagtgatc gaagcacgtc
    13201 ttgataaagg taaaggtcct gtgtcaacct tacttgtcca agaaggaaca cttcatgttg
    13261 gtgacccaat cgttgtcggt aatacttacg gacgtgtccg tgtaatgaca aacgatcttg
    13321 gccgtcgcga taaagaagca ggacctgcaa cgccagtaga aatcactggc ttgaatgatg
    13381 tacctcaagc aggtgaccgt ttcgtagtct tcgaagacga aaagacagca cgtgcagcgg
    13441 gtgaagaacg cgcgaaacgt gcattattag aaaaccgtgc tgccacaagc cgtgtgactt
    13501 tggataactt atttgaaagc ctgaaagaag gcgaattgaa agaagttaac gtaatcatca
    13561 aagcagatgt acaaggttca gcagaagcac tggctgcatc attgaagaag attgatgtgg
    13621 aaggtgtccg tgtaaaaatc gtccattcag ctgtcggagc aatcaatgaa agtgatgtaa
    13681 ccttagcagc agccagcaac gctattatca tcggtttcaa cgttcgtcct acaccgcagg
    13741 caaaagtgca agctgatact gaagaagtcg atattcgtct tcaccgtatc atctataaag
    13801 ccatcgaaga aatcgaaact gcgatgaaag ggatgctaga ccctgaattt gaagaaaaaa
    13861 tcaccggtca aatgatcgtt cgtgaaacct tcaaagtttc taaagttggt acgattgcag
    13921 gtgcctatgt aacagaagga tatattcgta gagatagcgg tgtccgtgta atccgtgacg
    13981 gaatcgtaat ctatgaaggc caacttgcaa gtctgaaacg attcaaagat gacgtgaaag
    14041 aagtcaaaat gggttatgaa tgtggtgcaa tgattgaaaa attcaatgac atcaaagtag
    14101 atgacgtaat tgaaggattt atcatggaag aagtcaaaaa tgactaaaaa ctgataaaag
    14161 gaggccaatc attatggcta actaccgtga ccgccgagtc ggtcaagaaa tcttaaaaga
    14221 agtcaatgat attttgcgca aaaaggtccg tgaccctcgt gtggagaacg taacgatcac
    14281 agatgtgaaa gttacggggg acttacagca agcaacgatc tattacagca ttttatctga
    14341 cttagcatca gataagaaaa cagcacaaga tggattgaat aaagcatcag gattgattcg
    14401 tcgagagtta gggcacaatc taagtattta taagacacct gaattgttct ttgaacttga
    14461 tgaatcagtt gtctatggca accatatcga tgaattgctt cgcgacttga acaaagacta
    14521 atcaaaaact cccgcaaatc ctgtgaaat
//
LOCUS       DAZKCH010000067        13978 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000067 DAZKCH010000000
VERSION     DAZKCH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.068"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            140..460
                     /locus_tag="ACG84X_002111"
     CDS             140..460
                     /locus_tag="ACG84X_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127950.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            912..1112
                     /locus_tag="ACG84X_002112"
     CDS             912..1112
                     /locus_tag="ACG84X_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9127951.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1259..4048
                     /locus_tag="ACG84X_002113"
     CDS             1259..4048
                     /locus_tag="ACG84X_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFP9127952.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4095..4622
                     /locus_tag="ACG84X_002114"
     CDS             4095..4622
                     /locus_tag="ACG84X_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFP9127953.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4643..5833
                     /locus_tag="ACG84X_002115"
     CDS             4643..5833
                     /locus_tag="ACG84X_002115"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFP9127954.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5873..7171
                     /gene="asnS"
                     /locus_tag="ACG84X_002116"
     CDS             5873..7171
                     /gene="asnS"
                     /locus_tag="ACG84X_002116"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFP9127955.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKITFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            7966..8640
                     /locus_tag="ACG84X_002117"
     CDS             7966..8640
                     /locus_tag="ACG84X_002117"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFP9127956.1"
                     /translation="MKKRILFIGDSITDAGRYRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIVAVDFFSGDKNE
                     RKKSEK"
     gene            8637..8978
                     /locus_tag="ACG84X_002118"
     CDS             8637..8978
                     /locus_tag="ACG84X_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127957.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            9008..9367
                     /locus_tag="ACG84X_002119"
     CDS             9008..9367
                     /locus_tag="ACG84X_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFP9127958.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            9627..9749
                     /locus_tag="ACG84X_002120"
     CDS             9627..9749
                     /locus_tag="ACG84X_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127959.1"
                     /translation="MNLDKLPATGFKLSCYPVKIKKASAGWIRAVAMIEEKKKE"
     gene            9891..11975
                     /locus_tag="ACG84X_002121"
     CDS             9891..11975
                     /locus_tag="ACG84X_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9127960.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKKRNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     RAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDPTGIDPKKFMQYVASAEQFSTHPIAQSVLEGYAGPLL
                     PTANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGY
                     LVIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDK
                     VQRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQP
                     SKIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVL
                     NAMRSLHVKNKR"
     gene            12286..13752
                     /locus_tag="ACG84X_002122"
     CDS             12286..13752
                     /locus_tag="ACG84X_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFP9127961.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4635 a         2430 c         2974 g         3939 t
ORIGIN      
        1 aaaaagaggt tgtgacgtgg tcacgacctc tttttgacga ttatgataca aaaaacatca
       61 tttatgaaca aaatgtgaat aacgggcgtt cttgagatat gattttaatt gggaaaaact
      121 tatcgataag gaggtcttta tgaaaaaaag actgttatgg tgtttgctgt ttctatccct
      181 aagtttaaca agtcagccag tttttgctga agaaacacag cggtctccta ttacaggcac
      241 acgtctgtac aaaaatgttt atgtacagac aacagatctt gattctgcga ttcctgaaac
      301 agaagaacgg tctttgcagc caagatttgg ttacttttgg tactgtccga cctgtgatta
      361 tgaaagttgc tggcatttct tacattctac agctgcagct tttgctttta ctcatactca
      421 gaaatatgat ggacatcatc ctgttattta tgaggtatag atatgagcaa aaaagaaaaa
      481 ctaatctcgt tgatcgtatt ggtttgcctt gttcttctgg taactgtcat aggctatcag
      541 aaataccatg agaacatcag acctactaaa gaatcttccc cagcctcgac cgttgaaaca
      601 gaaccgataa gtagtcagaa agaataattt ttttagttta aagaagaaca tcagagcaaa
      661 aaaacaccaa ctgaacaata tgtcgtttat tttaaaaaaa gttcggtttt tcactttatg
      721 taatcgctga gaaaactttt tttaataaaa aaagtcgaaa aactctagct tttttgtaaa
      781 cggtatgata tactatagga gtagtttttg ttcggtaatc tgtggtagct tgtttcaaat
      841 aaacatcttc cagatataca ccattcaagt aattgcaaaa tatgtgttga tacacaagga
      901 ggatttttat tatggaaaca ggtacagtaa aatggtttaa ctcagaaaaa ggatttggat
      961 tcatcactgc agaaaacgga aacgatgtat tcgttcattt ctcagctatc caaggcgacg
     1021 gattcaaaac tttagaagaa ggccaagcag taactttcga tgttgaagaa ggccaacgcg
     1081 gacctcaagc aacaaacgtt actaaagctt aattaaccta tactaaaaaa taaacgccca
     1141 gacatttgcg tgtctgggcg tttttgtcta ttttctttaa aaagcgatga gagtattttt
     1201 ctgcactttg tagtataatt tcaaaagaac attagaggca ggagaagagg aagatatttt
     1261 gaaaccaaga acttatgcag tcgttgatat cgaaacgact gggacgaatc caaaagaaga
     1321 tcggatcatc caatttggct gcgtcatgat tgaatcaggt cggatcactt cacgtttttc
     1381 gatcgatatt catccagggc ggaagatttc aaaacaaatc cagcatttaa cagggatcac
     1441 gaatcaacgc gtccaaaaag cgccttattt cgaagatgtc gcccaaacga tttacaatct
     1501 tttggcagac accatatttg tcgcgcataa tatttatttt gattataatt ttttgaacca
     1561 tgaactcatg cgatgcggac ttcctagttt gaagatacca ggcatcgata cagtagaact
     1621 tgcacaaatt ttcttgccga cggaaccaag ctttcgctta gctgatttgt cagaaagcct
     1681 tggatttatt catgagaatc ctcatcaggc agatagtgat gccgaagtga cgggtcaact
     1741 tcttttgctg atcgaagaac ggatgagaaa attgccaatc atcacgttag agcagattgc
     1801 gcgattaagt agacacacag gtatggatac gagtcgtttc atttatcatg tgattgaaga
     1861 aatgaaagaa aaaccagagc cacttgatcc ctcattagaa atcgtcgatg ggctagcttt
     1921 gcagaaaaaa gaagtggaac tattcacatc cgtccattat ggcgagcgga catatccaag
     1981 aaaaaaacaa gcaaaagaaa aaatgtttgg taaaacactg atgtatcgaa aagaacagaa
     2041 cagactgatg aatgcggtct acgaccattt cacaaaagat gaatcaaaag atttgatgat
     2101 cgaagcagct acaggaatgg gtaaaacaat cggttatctg ctgccattga gttatttggc
     2161 tacacctgaa aaacccgctg tcatcagtac cgtttcgcta gttttgcagc agcagatcat
     2221 agaaaaagac attccattgc tgaatcaatt gctagatcag cccatacaac ctgtaattat
     2281 caaaagctat cgccactata ttgatttaca gcgttttaaa ggcacacttg tggaaccgcc
     2341 agaacaaaaa caatatgctt tgtatcaaat ggcggtctta gtttggctga cgcaaacgaa
     2401 gaccggtgat ttggatgaat tacatttaac aaatttgaac cattcattct ttgcagatat
     2461 cgcgcacaga ggtattggat ttttagcaag aaatcagtca ttttacgaac aagactttgt
     2521 tcgtttcttg caaaagaaaa tcaggcaaag taattttttg attgtcaatc atgcgttttt
     2581 aatacaagaa acacagcgaa aagaaccatt gcttccagct agtccatttt tgttgatcga
     2641 tgaagtacat catttgccgg aaatcgctga aaaagtaaat gacaaacgat taagtattaa
     2701 ctatttccat aaacaaatcc agcaattaga agaaccaaat cagctgtttg accgaataca
     2761 aagctattta ccgaaagaac atgaagcctt acgctggtta tcgatttatc gagaagaact
     2821 ttctgcgcta tgcgaagcac agatttgtat ggcagaagga ttaatgagtt tagtgagcgg
     2881 caagcaacct aacggacagt atccagaaga agtcatgatg acaaaagaga tgttggatca
     2941 gctgccactg gaatctggga cagccattga tcacctgcag cttttttatc aggagatcca
     3001 gcagctacag tcacaaatgc gtctgacttt tgagattatc caagaaagct ggacaaacca
     3061 gatgcggatc gatttagcaa gtttatatag cttatttgat caattagaca agcagtactt
     3121 gctgatggat caatggctgg aagactggcg agatcatttg atccattggt tcgttcctgg
     3181 gaacacagcg cagcagatga tttttcatct ccatgatttt caagcggcta tgttgccgtc
     3241 gactgtttgg tatcctcgat atgatcgtat tctttatatt ggaggaacgc tgaagatcgg
     3301 ccctaatcga cactatctct ctaagcggct tggcattgaa gcagcacctc ttaaagtgat
     3361 tgcctctcct tatgattatg agaaacaggc aaggatctat gtgccaaaag aggcacctgc
     3421 cgtccatcaa gtcagcaatc aagcatatat cgattattta gagacagcac ttacaggtct
     3481 gatcgaacaa gaagatcggc caatacttgt gttattcact tctcatgatg ttttgcagaa
     3541 ggtctatcag aaaatgcatc tgtctatgct agaaaaagga cgagaaatac tagctcaagg
     3601 gtttggcgga agccgggaga agcttttgaa acgcttcatt ttgtcagaaa aaagcgtatt
     3661 gtttggcgct gacagctttt gggaaggtgt agatttgcct ggggatgctt tgcagatcgt
     3721 tgtagtcaca cgtttaccct tcgataatcc gcttcgcccg atggtcaaag ctaggaacgc
     3781 ttatttagaa tcagagggga tcaatccttt ttaccaggaa tccgtaccta aagcagcttt
     3841 gaagttacgc caagcattag gtcgcttgat aaggacggag acagatcgtg gcgtattgct
     3901 tattttggat cgaagactag tcactgcaaa atatggtgca cggatcatcc atgcattacc
     3961 gaaaaaagta ccgatcaaag agctagctat ggaggaaatc tatcaggaca tccatgaatt
     4021 cttaaagaaa aatgaagaag gaagttagag gagctgtctt ttttcataat taaaatctgc
     4081 tataatgaaa aggaatgaag ataaaggagc gacgaccctt gaagaaaaaa cagacaaagg
     4141 aaaaaacgat taatcgcgtg ttacttggct tgatcgtatt tttattagcg gtcatcgtga
     4201 tcagctcgat tttttacttg cgttccagtc gtccggcggt gcaggcgaag aaagaagcag
     4261 tagaaatcgc aaagaaatat gcaaatcttg aggaagccga tcatttttat tggtttactc
     4321 gaaagaagac atacttttca ctgacaggta caaatgataa aggaaaagaa atcgccgtta
     4381 tcattcctaa atctggtgaa aaagtaaaag tattggatca aacaaaggga ctgactgaaa
     4441 acgaagcaaa acagacaatt gctgcggccc atcctgaaat ccaaatcgaa aaagctgctt
     4501 tagggatgta tgatgatcag cctgtgtggg aagtagtagg aaaagaaaca aatgggaaac
     4561 tgaattatta cctgattggc tttgaatctg gagatgaagt caagacaatc aagggaattt
     4621 aaaaggtaaa ggaatgaatg ggatggagtt atcaaaaaga acaaaacgat tagaaccgtc
     4681 tgtcactttg gcagctgcgg caaaggccaa ggcattaaaa gcaaaaggca gagatgtgct
     4741 gagtttgact gtgggagaac cggattttgc gacaccagaa aacatccaag aagcagcaat
     4801 cgaagcaatc cgcaatggga aagctagcta ttatacacca acagcaggaa tcccagagct
     4861 tcgacaggca atcgttgatt atctgaagaa aaactatgga cttgtctatg aaccttcaca
     4921 aacagtcgta acagacggag cgaaatttgc tttgtatacc cttttccaaa cgatccttga
     4981 cccgcaagat gaagtcatca ttcctgtgcc ttactgggtc agttacggtg agcaagtaaa
     5041 actggcagaa ggacttcctg tctttgtgaa aggggaagaa tccaatagct ggaaagttac
     5101 tgttgaacag ctagaacaag cacgttcaga aaaaacaaaa gccgtaatca tcaattctcc
     5161 atcgaatccg actggaatga tttatagcaa gaatgaactt caggcaatcg gtgaatgggc
     5221 agtaaaaaat gatattttga tagttgctga tgatatttat ggtcgtttag tttataatgg
     5281 caatgagttt actccaattg caacgatttc agaagcaatc aaaaatcaga ccatcatcat
     5341 caatggcgtg tctaaaacat atgcgatgac aggctggcgc attggttatg cggtggggaa
     5401 ttctgagatc atcaatggaa tgattgctgt tgcttcccag tcaaccagta atccgacagc
     5461 agtcagtcaa tatgcagctg ttgaagcatt gaaaggtgag caagatacag tagaagaaat
     5521 gcggaacgcc tttgaagaac gcctgaatac gttatatccg cttgtggcag aactgccagg
     5581 tgtttctctt gaaaagccgc aaggagcttt ctatcttttt cctaatgtaa aagaaacgct
     5641 acgcatgtgt aaatatgaaa atgtcacaca atgggtagaa gatcttttag aagaaacagg
     5701 ggtagcgctt gtgactggcg aaggctttgg ggcaccagaa aatgtccgca tgagttatgc
     5761 tactgatcgc gctacgttag aagaagcggt acgcagaatc aagcaattta ttgagagtaa
     5821 aagtcaaaat taatcctgaa gaaattcaag gaatataaaa ggagagtcat acgtggaaca
     5881 aattcaaatc atcgattcga aaaaccatgt gggagaaaca gtaacaatcg gcgcttgggt
     5941 cgcaaataag cgatcaagcg gaaaaatcac atttttacaa ttaagagacg gaacagcctt
     6001 tttccaaggt gtagttgtaa aaagcgaagt gtcggaagaa gttttccaaa cagctaaaaa
     6061 tctacaccaa gaaacatccg tgttagtaac tggagaaatc cgtgaagaca gtcgttcaaa
     6121 atttggttat gaaatcggaa ttacaaatgt ggaagtggta agcgagagcc acgattatcc
     6181 gatcacacca aaagaacacg gaacagactt cttgatggat catcgtcatt tatggctgcg
     6241 ttcttcaaga caacatgcga ttatgcagat cagaaatgaa atcattcgtg caacgtatga
     6301 attctttaat caacatcatt ttgtcaaaat tgatccgccg atcttgactg gttctgcacc
     6361 agaaggcact acggatctat tcgaaacaaa ttactttgat caaaaagctt atttatctca
     6421 aagtggccaa ttatacatgg aagctgctgc tatggctttc ggaaaagtct tttcattcgg
     6481 tccgactttc cgtgctgaaa aatcaaaaac acgacgtcat ttgatcgaat tctggatgat
     6541 cgaaccagaa atggctttca ctcatcaaga agaaagttta gaagtacagg aacaatatgt
     6601 agcattctta gtacaaaatg ttttagatca ttgcgaatac gcattagatg tactaggacg
     6661 agacaaagaa gtcttaaaaa cttatacaaa attgccattc cctcgtatta cttacgatga
     6721 tgcaatcgaa ttactgaaga aaaatggatt tgatgacatc gaatggggcg aagactttgg
     6781 ttcacctcat gaaacgttca ttgcgaattc attcgaacag cctgtcttta tcctaaacta
     6841 tccaaaagcc atcaagccat tctacatgaa accacatcca acaagagaag acgtggtaat
     6901 ttgtgcagat atgatcgcac cagaaggtta cggtgaaatt attggcggaa gcgaacgggc
     6961 aacggactat gatttcttgc tagaacaaat ccgtaatcac ggtttggatg aaaaagaata
     7021 ttcatggtat cttgatctac gtaaatacgg ttctgttccg cactctggtt ttggtctagg
     7081 tcttgaacga acagtcactt ggattgctgg tatcgaccat gtacgtgaag ctattccatt
     7141 cccacgtttg ttgaaccgaa tttatccata agaggttgtg cgcctgccgt tcagctccga
     7201 gtcacaagga gtaatttcaa aaaacagttt ttcatgtttg atgactattg tgacttgtgg
     7261 ccggagagca acgtttattt aaaaaaaaga actgcgaact ctcgcagttc ttttttttaa
     7321 atacgggata atggaagttt ccagcagaca agagaagaaa gcaaaagaaa ttgctatttg
     7381 attcacaagg ttctataacg aaatcgcaat caatcaaaca tttacaaaga aggtaattca
     7441 aatggaaatc tgatttgatg atgcttctgc tgttgaaata aagcagcatc tagcacctga
     7501 aaacaaacta atagtaacat tcgaagatgg agtaggtccg tattttcagc atgcaataat
     7561 ccatatgtaa gttcaattca cccttgaaat catcggacca gataaagtta tgaccaatct
     7621 atcccaagca atctagaaga gatattagta aagggacatt tactagaagt cttagatgag
     7681 cctataaata tatgtttcga tggcgtcatc agtggtctga ttgacggaag cttgggtgtg
     7741 atcgatctct ctggaccaaa caacgaagga atcaagggga atccggcacg ttaagaaaaa
     7801 aatagcataa aaaactagac acttgatgag cgttcattca attgtttgaa ggaactaggc
     7861 tggtgtcatt ttttatacat atattttctc tttcgtcttg atagggctta tgggataata
     7921 taaggaagaa aatcatcgtt ttattcaaaa aggagttttt gacaaatgaa aaaacgtata
     7981 ttatttatcg gtgatagcat tacagacgca ggaagatacc gagcagaagc aactgatcta
     8041 ggtaaaggtt atccactttt gattgccgga aaactaatct cccaatatcc aacgatggaa
     8101 tttgaatgca tgaaccgtgg gataggagga gacaaaattg cagatctgca agtacgctgg
     8161 caagaagatt gtttagcttt acaacctgac tatgtatcga ttttgatcgg aatcaatgat
     8221 acctggcata atactagcga tcaggctata ttcggaactg agaaatctgc tcagcaattt
     8281 gaatccgttt atcgaaaatt actaaatgaa cttcaaacag cggaaatctg caacatcatc
     8341 ttgatggagc cgtttgtact tcctataacc gacgaccgtc atggctggcg taaagactta
     8401 gaccctaaaa tccaaattgt tcgtaaactt gctaaggaat atggcgcatt gctggttcct
     8461 ttagatggta tattcaatgc tttagggatt gcttatggtt tttcgaaata tacaagagaa
     8521 gatggggtcc acccaacgat tggcggacat gagatcattg cacaaagctg gatagatgca
     8581 attgtcgcag tcgatttttt tagtggagat aaaaatgagc gaaagaaaag tgaaaaatga
     8641 tggaaataag gtgggcagta aaagaagatt tacctcaaat caatcagctg attactgatc
     8701 atccagaatc attcgtaaaa gcaaaaacgg cagctgacct aaatgataag aataaactat
     8761 tgctcgttgc tgtaacaaaa gaaaaacgga ttatcggatt tgcgcaagcg gacgtgcaac
     8821 agtcagaaga acgattggat cagcgaccat caggaaaact aatccaacac acattagtaa
     8881 caaaagaaaa tacggaagaa atccaaaaaa aatttgcaga atacttgatg ctggaagcta
     8941 aaaaaagaag aataaaatca atttttgccc agttttaatc aaaaacagta atagaaggag
     9001 aaatacaatg agttgtttag gaaatgtcat ctggtttata ttcggcggac taatcggtgg
     9061 tcttagctgg ttagcagcgg ggatactttg gtgtatcacg atcataggta tcccaatcgg
     9121 tatgcaatgt tttaagatcg cctccctttc ttttgcgcct tttggcaaag aagtaattta
     9181 tcaccagtct ggcatgtcat tgatcgttaa tatcatctgg ctgatcgttt caggcctacc
     9241 aattgctctc gcacatgtcg tcagcggcat ccttctatgt atcacgatca tagggatacc
     9301 ttttgccaag caatctttca aacttgctcg attggcgttg atgccattcg gtgcagaaat
     9361 tgtataaaag agaataataa aggttagata aagcatagag ccaggtggga tacatgtatt
     9421 tcacctgact ctatgcgttt tcctgtataa gttcttctat gtgactttta cgtcttttat
     9481 ttatatgggg ttactgttta tggaaagttg aaataatttt cattaaagaa ctctttctat
     9541 atttttgaaa gcgtagtgga gcttcgtata tctgggaagg acattttgca gggattgaaa
     9601 aaagatattg tcctatcgaa aaattaatga atttagacaa attgccagca acaggcttca
     9661 aacttagttg ctatcctgtc aagatcaaga aggcaagtgc gggttggata agagcagtgg
     9721 caatgatcga agagaaaaag aaagaataag ccaaaacatc tgtatggaag aaattttccg
     9781 atgcagatgt ttttcatttt ttctttcgga taccttgaca tatgaataac cattcattta
     9841 taattagtta tgaagagata ttcatatgtt gaggcgagga ggtcattaaa atgaaaagtt
     9901 acagattaga aggtttagat tgtgcgaact gtgcaatgaa aatcgaaaaa ggagttcaga
     9961 aaatcaatgg agtcaaggaa gcaacggtaa acttcacttc tggaaaacta acgattgacg
    10021 cagaggaaga tcatttggct acgattgaac aagaaacaaa aaaagtagtg aaggaattag
    10081 aaccagatgt caaagtaaca gaaatagata aggaaaaagt atctgaacat ggaaatgaaa
    10141 aaaagagaaa tacgctgttc cggattttat tttcccttgc aggtatcgct ttattgctat
    10201 tatttgattt taatgaacca attcgcttga tagggtattt attgatttat ctgctgatag
    10261 gatatgatgt agtgaagaag gcagtgatga atatcgtcaa aggaaaaatc tttgatgaga
    10321 attttcttat gtctgttgct acgattggcg ctatgttgat cggtgaatat ccagaagccg
    10381 tagcagtgat gctattttat caaatcggcg agtatttcca aggattggca gtcagtcatt
    10441 caagaaaatc gattcgcgaa ttgatggcga tccgtccaga aacagctcac gtgcagacgg
    10501 cggaaggatt gatgaccgtg aaccctgaag acgtgctgat cggtcagttt gtacttgtga
    10561 agcctggtga acgtgtaccg ttagatggaa cgatcatcga aggagaatca ttagtcgata
    10621 cgtcagcact tacaggagaa tcagtcccta aatctgtata tgttggtgaa acagtattaa
    10681 gcggatttat caataaaaat aaaccatttt tagttcaagt agaaaaatct tatgaaaatt
    10741 ctactatcag caaattatta gaattagtag aaaatgccag cagtaaaaaa gcaccagctg
    10801 aaaatttcat tactaaattc gcgcgctatt acacaccagt cgttgtagga ttggccgttt
    10861 tattagctgt tttacctcca cttgttgttt ctagagcggc gttttctgaa tggatctatc
    10921 gagcattgac atttttagtg atctcatgtc catgtgcatt agtgatttcc gtgccactta
    10981 gtttctttgg cggtatcgga ggagcaagta aaatcggtgt attagtaaaa ggttcaaatt
    11041 acttggagtt gcttgcacaa actgagacag tggtattcga taaaactggc acattaacga
    11101 aaggtgactt ttcgatccag acgatcgatc caacaggaat tgatccaaag aaatttatgc
    11161 aatatgttgc aagtgcagaa cagttttcta cacatccgat tgctcaatct gttttagaag
    11221 gctacgcagg tccgctttta ccaacagcta atatccagga atttgcaggt gaagggatct
    11281 tagctgaagt tgatggcaaa caagtattag taggtaatca caaattgatg gaaagatttg
    11341 aaatctcttt tccttcaagt caagaaatcg gtacattgct ttatctagcg atcgatcaaa
    11401 gttacagtgg ttatcttgtt attgcagata ccttgaaaga agatgccgta gacgcattgg
    11461 ttcaattaaa acaggctggt gtgaaaaaca cagtcatgtt gacgggcgac tcgaaaaaaa
    11521 ttgctgatca tatcgggaag caagtaggcg tggacaagat atatagcgaa ttgcttccag
    11581 aagataaagt gcagcggtta gaggaaatct tacaaagtaa caataaaaag accgcatttg
    11641 tcggagatgg aatcaacgat gcaccggtgc tagcaagagc agatgtagga atcgcaatgg
    11701 gtggattggg aagcgatgct gcaattgaag cagcagatgt agtcatcatg aatgatcaac
    11761 catcgaagat tgcagaagca atccatttag caaagaaaac attgaaaatc gtcaaacaga
    11821 acattgtctt tgctattggg ataaaaattt tggtactttc cttaggtgct tttggttttg
    11881 catcaatggg agatgcagta tttgcagatg ttggggtgac agtattagct gttttgaatg
    11941 ccatgcgaag cttgcatgta aaaaataaac gttgatcaat gaagaggacg aatgaacgtc
    12001 ctcttttttt tatatccttt tcttaatgaa aaatgtaaag aaaatagata ggattataaa
    12061 ataactaatg tttttaattt tgcagaaaat tcaaaatagc ttgaaattca ataaggtcaa
    12121 tgaaataaaa gaaaataact tatttttttg atggaaaaaa tatgaaaaaa cgatgtgtat
    12181 taaataaaag aatacacaca taaaataaca ctgtcttgta agtttgttaa aaattgaata
    12241 tgattacatc tggataacaa atttttatca taaaggagag aacgaatgaa caacaaacaa
    12301 ttacgctggt ttactgttgc gttaattgca tttaacatgg tttggggcat ggggaatgta
    12361 gttaataact atgctcagca aggagtatca gttgtcacct cttggctatt gattttggcc
    12421 atttatttta ttccatacgc attgatcgtt ggacaattag gatcagcctt caaggatagt
    12481 aaaggaggcg tcagttcatg ggtcgaaaat acgacatcta ataaacgact ggcatactat
    12541 gccgcttgga cttactgggt cgtccatatt ccttatttgg cacaaaagcc tcaagcaatt
    12601 ctgattgctg gtggttgggc agtccaagga aatggaaata tcgtaaatac gatgtcagta
    12661 caaatggtag cagttatttc acttattata tttcttgcct ttttatattt atcaacaaaa
    12721 ggactttcta ctttgaaagt gattggcgga ctggccggaa cagcgatgtt cgtcatgtcg
    12781 atcttattta ttcttttagc tgtaacggca ccgttcatca atccaacgat ggaatttgcc
    12841 acaccacata tgaatcaagt gaaaacatat attccaacat ttgatttcag ttatttcaca
    12901 accgtttcga tgctagtatt tgcagttgga ggggcggaaa aaatatcccc ttatgtcaac
    12961 tctacaagaa atcctgcaaa ggaatttcct aaagggatga tcttcttagc agcaatggta
    13021 gggatttgtg ctgtattagg ctcagtcgca atgggtatgc tgtttgctag cgataatatc
    13081 cctaaagact tgatggcaaa tggggcatac agtgcttttc aaattttagg taattactat
    13141 ggtatcggta actcattgat gatcatttac gcattgacaa acatgattgg acaaatctcc
    13201 gcattagcct tttcaattga tgcaccacta aaaatcttgt tagcagatgc ggatccagaa
    13261 tttgtaccaa actggctacg taaacgtaat cgtaaaggta cattggtgaa tggttatctt
    13321 ctgacaggta tactagtagg aatcattatt ttgttgccga tctttggtat caaagatatg
    13381 aatgaattag taaaatggtt gacgaacttg aactcagttg tcatgccaat gcgttaccta
    13441 tgggtgttct tggcatatat gatgttgaat aaagcttata agaaattcaa ttctgaatat
    13501 aaatttgtta aaaatccaaa aatcggtttt atctttggtg cttggtgctt tgccttcact
    13561 gcgtttgcat gtatcctagg aatggtgcca aaagtagatt atactgctga tcctaaagca
    13621 tggtggttcc aattattcac gaatatcatc acaccaattg tcttgatctt attaggtatg
    13681 atcttgccag caattgctcg tcgagacaaa aacaaagaaa ttactgaacc agaaacagtg
    13741 gttcagcctt aaaatagaaa tacttgttac aagaggttgt gacagaagct acttctggaa
    13801 caccgtgaat cagaggttgt gaaaaagctg tcctgcatca agtaataaga acagccaaac
    13861 aaaaatagct cctcatattt tgccgttttt tgagctaatg ctgaaggtca gctgattgaa
    13921 caccatttat tcgaaacaag ggactttgac acgacttttg tcacagtccc ttgttttt
//
LOCUS       DAZKCH010000068        13959 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000068 DAZKCH010000000
VERSION     DAZKCH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.069"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..135
                     /locus_tag="ACG84X_002123"
     CDS             <1..135
                     /locus_tag="ACG84X_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9127962.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            complement(313..2310)
                     /gene="tkt"
                     /locus_tag="ACG84X_002124"
     CDS             complement(313..2310)
                     /gene="tkt"
                     /locus_tag="ACG84X_002124"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFP9127963.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2412..2663)
                     /locus_tag="ACG84X_002125"
     CDS             complement(2412..2663)
                     /locus_tag="ACG84X_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFP9127964.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2810..3433
                     /gene="lexA"
                     /locus_tag="ACG84X_002126"
     CDS             2810..3433
                     /gene="lexA"
                     /locus_tag="ACG84X_002126"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFP9127965.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3613..3831
                     /locus_tag="ACG84X_002127"
     CDS             3613..3831
                     /locus_tag="ACG84X_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127966.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4120..4632)
                     /locus_tag="ACG84X_002128"
     CDS             complement(4120..4632)
                     /locus_tag="ACG84X_002128"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFP9127967.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="ACG84X_002129"
     CDS             complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="ACG84X_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFP9127968.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7085..7528)
                     /locus_tag="ACG84X_002130"
     CDS             complement(7085..7528)
                     /locus_tag="ACG84X_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFP9127969.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7529..8317)
                     /locus_tag="ACG84X_002131"
     CDS             complement(7529..8317)
                     /locus_tag="ACG84X_002131"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFP9127970.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8314..9255)
                     /gene="rnz"
                     /locus_tag="ACG84X_002132"
     CDS             complement(8314..9255)
                     /gene="rnz"
                     /locus_tag="ACG84X_002132"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFP9127971.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9432..10019)
                     /locus_tag="ACG84X_002133"
     CDS             complement(9432..10019)
                     /locus_tag="ACG84X_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFP9127972.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="ACG84X_002134"
     CDS             complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="ACG84X_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFP9127973.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11841..12851
                     /gene="gap"
                     /locus_tag="ACG84X_002135"
     CDS             11841..12851
                     /gene="gap"
                     /locus_tag="ACG84X_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFP9127974.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12936..13871)
                     /locus_tag="ACG84X_002136"
     CDS             complement(12936..13871)
                     /locus_tag="ACG84X_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9127975.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3863 a         3126 c         2454 g         4516 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatat tctcaagaaa cacaaactaa tccgaagaat
      181 tctttgtttt gtcatttaaa tgtaacatag ccgaaaacga aaagtaatat tgatttattc
      241 ttctaacaca taaagaacag ctgtctccaa cttgcagaca gctgttctta tcagtcaaac
      301 aattgcttgg atctatgata gttgattgta cgtattcacg acattttcta ctgtaaatcc
      361 aaattcttct aaaattttag tgccaggggc agatgcaccg aaatgatcga ttgtaatcgt
      421 tgcgccctct gttcctacgt agcgttccca tccaaatgat gcagcagctt cgatagccac
      481 acgtttcttc actgatttag gaagtacact ttctttatat tcagaagatt gtttttcaaa
      541 gaggtcaaag cttggcatag aaacaacaga aacatctttg cctttttcag ccaattcttt
      601 ttgagctttc acagccaaat caacttcaga acctgttgca atcaaaatac cttctggtgt
      661 ttctccttgt gatggagaaa gaacatacgc gccttttttc accatttcat ctgctacttc
      721 ttttgtagaa ggcaatactg gaaggttttg acgactcaat acaaggatag taggcgcatc
      781 tgttgtctcc atcgctactt tccaagcagc acgtgtttca tttccgtctg ccggacgaat
      841 cacttgaaca ccaggcatgc agcgaacaga tgctagttgt tcaatcggtt cgtgcgttgg
      901 tccgtcttct ccgacagcaa ccgagtcatg tgttaagacg taaacaacag gagtatgttg
      961 gattgctgct aaacgaactg ctggtcttag ataatcgaca aagacaaaga atgttccacc
     1021 gtagatacga gttccgccat gaagttggat accattcata gccgaagcca ttgcaaattc
     1081 gcggacaccg aaccagatgt tgcgtccttc ataatgttca ggagtgaaat ctttatctgc
     1141 agccaccatt gtattattgg aacctgacaa gtccgctgaa ccaccccaga agcttggtat
     1201 agctttcgat aattcttgga tgacttcttt acttgaaaca cggcttgctt gactgcttcc
     1261 aacttcataa gttggcaatt ctgcatccca gttttctggt agtttgccat caaaagcatc
     1321 ttcaaattgt tgtgctaatt caggataagc ttttttataa ttggcaaaca tttcattcca
     1381 tgcatcttca gctttttgtc cttcttctat catcgtttga tggaagcggg cagctacttc
     1441 ttctggaaca gtgaaatctg gatactccca accataaact tctttagcca tcttgatgcc
     1501 atcttcacca agaggagcac catgaacagc agatgttcct tctttaggag caccatagcc
     1561 gatgactgtt tttacttcga tcaatgttgg tttgtctgtt tcagcttttg cttcttcaat
     1621 cgctttagag attgcttcta ggtcatttcc gtctttcact aagatatgtt gccagccata
     1681 tgcttcatag cgagcaccaa cgttttctgt gaaagctttt gaagttggac cgtctagtga
     1741 aatatcgttt gaatcgtata aaacgatcaa tttccctagt ttcatatgac ctgccatcga
     1801 acttgcttct tgagataccc cttccatcaa gtctccgtca ccgcatattg catacgtata
     1861 gtgatccatc acattaaagt tttctttgtt atacgttgct gcaaggtgcg cttctgccat
     1921 tgccataccg acagccattg caatcccttg tcctaatggc cctgtagtgg cttctacacc
     1981 atctgtatga tgtacttcag gatgtcctgg tgttttagaa tcccattgac ggaattgttt
     2041 caaatcatcg attgtcactt gatagccagc taaatgaagc aagctataca acattgctga
     2101 cccatgtcct gccgaaagaa cgaaacggtc gcggtcagcc cagttttttg atgtcgttgg
     2161 atttactttc aggtgttttg tccataacgc atatgccata ggtgctgcgc ccatcggcaa
     2221 tccaggatgt cctgagtttg ctttttggac tgcttcaata cttaatgtac gaattgtgtt
     2281 aacgccaagt tggtcaattt tgtcaaacaa aataacccct cctattaatt taggtttttt
     2341 ttacctttat ttcttacact ttcattctat aagatgtcac acgaaaaagc aatctttttc
     2401 agtatttttt actaaaagtt gtcatttcgg ttgtgtaagc cttttttctt ttggatttct
     2461 tttaattttt ccggggtcac gtcattgccc tcaggatcga cgactttcat tccttcgata
     2521 tgatgacgca taccggaacg aaaagcttcc aaatactctt tgcgcaagtt gatttgttct
     2581 tgttcttcgg cttttgagag accattttcc ttctttttac gtgcaagttc attgatccgc
     2641 tctatttttt caggtgacag catgctcagc cctcctttta ctctccttca tattatataa
     2701 aaactgaaaa aaaaacaact agataaacta aataaaatac gaacattcgt ttgatttagc
     2761 gctttttata tggtactatt tatttatcaa gtgaaagaag gtgtaccttg tggcccgaca
     2821 aactgaatca agacaaatcg aagtcttacg atatatccat gaacaagtaa cccaaaaagg
     2881 atacccgccg actgtccgtg aaatcgggga agctgttcag ctttcttcta cttctactgt
     2941 tcacggtcat cttgcacggc ttgaaaaaaa agggtttatc caaagagatc cgacgaaacc
     3001 tcgtgcaatc gagttgacaa aacaaggttt agaaaagatt gggattcgtc caacaactat
     3061 tccagtactt ggcgtcgtaa cagctggaga acccatttta gcagtagagg atgcttcaga
     3121 cttctttcca atccctccta atctttcttc cgaagaaggc agtctcttta tgctgacaat
     3181 tcgtggagat agtatgatca atgctgggat attggatggt gacaacgtga tcgttcggaa
     3241 gcaagaaact gctcaaaatg gcgatattgt cattgcaatg actgccgagg acgaagcgac
     3301 ttgcaaacga ttctataaag aaaaaaactt tttccgtctg cagcctgaaa acgacttgct
     3361 cgaaccaatc atcttagatc aagtatctat attaggacga gtagtaggac tttatcgtag
     3421 tcatatctat taattgctac taattaaaag aaaacttttt aaaaagagtt tgagacgttg
     3481 gtctcaaact cttttttcgc ccgggttctt cttctttcaa atttttatca cttccctctt
     3541 tacaaaccga acaaatattc gtatactaaa tatacgaaca attgttcgca taaattaaag
     3601 aggtgagaat tcatgaaatc aatgagacgt cttggcttag tattaactgt tttgttttta
     3661 ggtattatta ttggtaattt cggcatacgt ccagctttac ttgtgtttgt tccgttattt
     3721 actttgtggt tcatgttgtg ggatgaaaag aagtaccgtc aatctgagcg gcgcagaatt
     3781 catgaagatc atttctatca tgagccctac tacagatcca ggcaatcata ataaggattg
     3841 actgctaatt attcaaaaga caagaagtta aacttttacg ggggtgtgac aaaaatcggt
     3901 cacatccttt ttttcgaata aacggtgttc taaagccagt ttttcggtat taagtcaaat
     3961 tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat ttataaaaaa
     4021 atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt taaaatcgct
     4081 tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca ttaatgtaat
     4141 gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga tcaaaaatgc
     4201 gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt tgattgttcc
     4261 tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa tggcatcctt
     4321 atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga tggtttctcg
     4381 aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat aagcaacagg
     4441 acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc gtttttcttt
     4501 tgcataattt acgatttgtt tagtagcttc ccgataagcg tcaccatctg ccatcagtgg
     4561 ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg caatataatc
     4621 ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg gtaggaatat
     4681 cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgtcgctgg tataatctgc
     4741 tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg ttctctattg
     4801 taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt tcagggatac
     4861 gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct tgagaatgga
     4921 tcaatttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa taggcctcat
     4981 caggtgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa acttctttca
     5041 gatccgctaa atcatctgga caatccataa caactagaga gtttggtttt cttttttcaa
     5101 ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg ataatctcag
     5161 gcacgaattt caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc gacgttcggc
     5221 tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc acagaaaaat
     5281 cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa agctttccta
     5341 ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca aaagcgaccg
     5401 catcaagctg actcgatgca tcggaaagga caaatttcag atgctgttgg tttgctccga
     5461 ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa ggattatccg
     5521 taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact tcatttggca
     5581 gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga tgatcgacta
     5641 tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc gttaaaccga
     5701 ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca agcatttcaa
     5761 aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct tcttttaaag
     5821 taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca atgcccaaaa
     5881 cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta ttgaccatcg
     5941 ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg atctcattca
     6001 atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac gagacggcag
     6061 gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa aaaccgatcg
     6121 ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc tgaagtccta
     6181 tccgttctga atgatgaatg gcatcgattc ctaatgaaac aaggattcga ttctcatcag
     6241 tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat tctgcaggcg
     6301 gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc aaatctggaa
     6361 atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct ggtaaattct
     6421 caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga gcgtatgcta
     6481 ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt ccttcttcga
     6541 tcttttcttg gtataccgat tggtttggtc catacccatg ctcaaatcga tttggcagga
     6601 atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt gcactggtga
     6661 tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt acagcttctt
     6721 ggattcggct gattgcttta tccatatcgt gtatcagata cggatcatgt aattcttgtt
     6781 cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt tgccacagta
     6841 acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag gattcagaag
     6901 gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca ctcctaactt
     6961 agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa aaacagatca
     7021 gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt atgaaatatc
     7081 cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt tcttccggcg
     7141 ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa gcagcttcca
     7201 actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct tcaattttct
     7261 tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt tgcttttttt
     7321 gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc agcgcagaac
     7381 cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt acaggaacat
     7441 ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat ccaagaatca
     7501 cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg ctggctaaat
     7561 aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa ataaacggtt
     7621 gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc aacttggcag
     7681 gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca gccttatcga
     7741 agaaatttgt ctcgattgga cctggattca ctgtcgtaac agctacgcca agtggtttca
     7801 attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca gaataaaccg
     7861 ttgattttgc agttgccatt tttccagcca tagaggcgat attaatgata tgaccttgtc
     7921 ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct aagatgttga
     7981 cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg aaaatcccaa
     8041 aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc ttttcatata
     8101 attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc tctttgccgc
     8161 tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt gcgcaactta
     8221 taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga ccgcctgaac
     8281 tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct cgcgaaatgg
     8341 aatctcaatg ctatcaaaat ctttcataat cgtcgtgttt tcaaacactt cttgtgcttc
     8401 tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag taagtagcag
     8461 ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg aatggaaata
     8521 gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca gaatatcgct
     8581 attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa tagtcacgat
     8641 tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc catcttctag
     8701 ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa tacctaattc
     8761 ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac gataaccaaa
     8821 actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat cagtaaaaat
     8881 cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg tttgcgaaat
     8941 acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct ctaatggcgt
     9001 atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa tatgatcgcc
     9061 gtgtaaatgt gtaatgaaaa ttttaccgat ttttctcgga cgaatagtcg ttcgcaaaat
     9121 ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct cgtctaaaag
     9181 tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac ctgttcctaa
     9241 aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt ttagggtaaa
     9301 aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa cgttctaaag
     9361 cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt gagatcctct
     9421 gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt ttgcggatgt
     9481 ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc tttcgcatca
     9541 tgcacatctt tttcgacatc ttcataatcc aagcgagtaa tttctccgcc taattccatc
     9601 attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat cagtcctgta
     9661 gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc ttttatttct
     9721 ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa aatccctagc
     9781 ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga tttgttatta
     9841 ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg atcatggctg
     9901 acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt gatttctgaa
     9961 aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg tttgctcatt
    10021 aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgaa aaataagaaa
    10081 agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta tcacagctcc
    10141 tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct cccttaaatc
    10201 tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa attcaaattc
    10261 aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa gagcttcatc
    10321 cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat gatcgaaatt
    10381 cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg catctgaatc
    10441 acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag tttcttcttc
    10501 cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg ctgtagcatt
    10561 caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg ggatgtcatc
    10621 agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta gattttccgg
    10681 tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta gcaagcgtaa
    10741 gttataagta gataattctt tgttgatggc aagatagtct tcataaggat ctcgtccttc
    10801 catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat gacgaaggaa
    10861 ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca agtctgctgc
    10921 ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttaggtacga gcgtcgtgaa
    10981 atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag tcgatttccc
    11041 gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta gttcgatttt
    11101 tcgctcttgt cctggttcac cgttttcagc aatttccggt gcaggattcc gaggagaggc
    11161 aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg tttgaccatt
    11221 ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg ttccttgtgg
    11281 tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca tcccattttc
    11341 acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac gtaacccttc
    11401 atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg gtccgccgtc
    11461 aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc cagctttcac
    11521 atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt attcatttat
    11581 ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta tcggtgaaat
    11641 ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt ttatcatttg
    11701 gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa tattctttgc
    11761 gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac agcaccccta
    11821 ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt gggcgtattg
    11881 gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta gtagcaatca
    11941 acgacttaac aagtccaact atgttagcac aattattgca atttgactct actcatggta
    12001 cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc gaagcaactc
    12061 gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac ggtgtagata
    12121 tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg catttagatg
    12181 ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc atcgtctata
    12241 acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt tcatgtacaa
    12301 caaactgttt agcacctatg gcttatttct taaataatga atttgggatc gaagttggta
    12361 caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga cctgtaaaag
    12421 gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat tctactggtg
    12481 ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa ggacacgcac
    12541 aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg aaaacaaaag
    12601 taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat ccttcattcg
    12661 ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa ggttcgatct
    12721 ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt aaaactgttg
    12781 catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta gaaaaattcg
    12841 ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat ccagtcaaag
    12901 gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg gcttaaaaat
    12961 tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc atgctcggct
    13021 ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt atctaacatt
    13081 tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg ctggtttttc
    13141 ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac ttttgtcact
    13201 agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc tagctgataa
    13261 gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt cacattatct
    13321 ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac accgtataga
    13381 acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg tacatagtct
    13441 ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg tcctcttgca
    13501 tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt ggtcatcgtt
    13561 tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt cgtttcagca
    13621 ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca atcgcttcgg
    13681 ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg tgttgtacca
    13741 ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt ataaaaataa
    13801 ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag gattttcatc
    13861 caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg aattagtata
    13921 atcaaagaat ctctactatg caatgttcat ttttataac
//
LOCUS       DAZKCH010000069        13724 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000069 DAZKCH010000000
VERSION     DAZKCH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13724
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.070"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(45..1364)
                     /locus_tag="ACG84X_002137"
     CDS             complement(45..1364)
                     /locus_tag="ACG84X_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9127976.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="ACG84X_002138"
     CDS             complement(1361..2014)
                     /locus_tag="ACG84X_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9127977.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="ACG84X_002139"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="ACG84X_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(2820..3539)
                     /locus_tag="ACG84X_002140"
                     /pseudo
     CDS             complement(2820..3539)
                     /locus_tag="ACG84X_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(3490..3699)
                     /locus_tag="ACG84X_002141"
     CDS             complement(3490..3699)
                     /locus_tag="ACG84X_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127978.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            complement(3681..3749)
                     /locus_tag="ACG84X_002142"
                     /pseudo
     CDS             complement(3681..3749)
                     /locus_tag="ACG84X_002142"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            3976..5249
                     /locus_tag="ACG84X_002143"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="ACG84X_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="ACG84X_002144"
     CDS             complement(5356..6387)
                     /locus_tag="ACG84X_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9127979.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="ACG84X_002145"
     CDS             complement(6394..7224)
                     /locus_tag="ACG84X_002145"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127980.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="ACG84X_002146"
     CDS             complement(7221..8036)
                     /locus_tag="ACG84X_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9127981.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="ACG84X_002147"
     CDS             complement(8033..8857)
                     /locus_tag="ACG84X_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFP9127982.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="ACG84X_002148"
     CDS             complement(8847..9947)
                     /locus_tag="ACG84X_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFP9127983.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="ACG84X_002149"
     CDS             10125..10910
                     /locus_tag="ACG84X_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFP9127984.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="ACG84X_002150"
     CDS             10943..11326
                     /locus_tag="ACG84X_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFP9127985.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="ACG84X_002151"
     CDS             11402..11533
                     /locus_tag="ACG84X_002151"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9127986.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="ACG84X_002152"
     CDS             11502..11738
                     /locus_tag="ACG84X_002152"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9127987.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            11750..11836
                     /locus_tag="ACG84X_002153"
                     /pseudo
     CDS             11750..11836
                     /locus_tag="ACG84X_002153"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(11816..12787)
                     /locus_tag="ACG84X_002154"
     CDS             complement(11816..12787)
                     /locus_tag="ACG84X_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFP9127988.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            13439..>13724
                     /locus_tag="ACG84X_002155"
     CDS             13439..>13724
                     /locus_tag="ACG84X_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008177227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9127989.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGY"
BASE COUNT         4163 a         2983 c         2379 g         4199 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atggcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagccgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttatccag actgtagaca aagtccattt tatggatgat
    13381 gtctacagtc ttttctttta taatagattt atgaaaacga atgcaaggag tgatagctat
    13441 gatgtctaaa aacaatacga atggtagaaa tcaatttgcg atgcttacga ttgatgatct
    13501 agttcctcaa gatcatctcg ttcgaaagat tgatgccgcg cttgattttg aatttattta
    13561 tccaatcgtc gaagccactt actccgattt aggtcgccca agtatcgatc cagtgattct
    13621 gatcaaattg gtgtttattc agtatttatt cggtatccgt tccatgcgac aaaccattaa
    13681 ggaagtcgat accaatgtcg cttaccgctg gtttttaggc tact
//
LOCUS       DAZKCH010000070        13694 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000070 DAZKCH010000000
VERSION     DAZKCH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.071"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            3..2117
                     /gene="acm"
                     /locus_tag="ACG84X_002156"
     CDS             3..2117
                     /gene="acm"
                     /locus_tag="ACG84X_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFP9127990.1"
                     /translation="MTSLIPVHVYADAGRDISSNVTSLTVDPTNITDGGNIKVKFSFD
                     EKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGTLTVRKDSAQVVFNENI
                     KNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVNVTKPASGSSSSVFYYK
                     TGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLDPSTFEINQIHLGEQKV
                     YRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKIMVSYKTIIENPEQINF
                     ENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGELKIFKYINDTEIGIPNV
                     TFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKEKEAPNWIDFDPLSSNE
                     LKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSIYFKLFRASTNNWEPVP
                     DAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGNDYVPSGYQKIENGLVVT
                     NENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQHKEVSEKDDWRYRFTNL
                     PKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNISIPGSHITPWKNFPEKT
                     EREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNKSKSILPKTSSKKSSFA
                     VIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2389..2874)
                     /locus_tag="ACG84X_002157"
     CDS             complement(2389..2874)
                     /locus_tag="ACG84X_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFP9127991.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    2964..3309
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3354..3995
                     /locus_tag="ACG84X_002158"
     CDS             3354..3995
                     /locus_tag="ACG84X_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFP9127992.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            4014..4649
                     /locus_tag="ACG84X_002159"
     CDS             4014..4649
                     /locus_tag="ACG84X_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFP9127993.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4667..5482
                     /locus_tag="ACG84X_002160"
     CDS             4667..5482
                     /locus_tag="ACG84X_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9127994.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5801..7237
                     /locus_tag="ACG84X_002161"
     CDS             5801..7237
                     /locus_tag="ACG84X_002161"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9127995.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7426..9873
                     /locus_tag="ACG84X_002162"
     CDS             7426..9873
                     /locus_tag="ACG84X_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFP9127996.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10103..11170
                     /gene="rlmN"
                     /locus_tag="ACG84X_002163"
     CDS             10103..11170
                     /gene="rlmN"
                     /locus_tag="ACG84X_002163"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFP9127997.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            11160..11366
                     /locus_tag="ACG84X_002164"
     CDS             11160..11366
                     /locus_tag="ACG84X_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9127998.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(11363..12466)
                     /locus_tag="ACG84X_002165"
     CDS             complement(11363..12466)
                     /locus_tag="ACG84X_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFP9127999.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13019..13567
                     /gene="aac(6')"
                     /locus_tag="ACG84X_002166"
     CDS             13019..13567
                     /gene="aac(6')"
                     /locus_tag="ACG84X_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFP9128000.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         4682 a         2297 c         2901 g         3814 t
ORIGIN      
        1 atataacatc actgattcct gttcatgtct atgcggatgc aggcagagat atcagcagta
       61 atgtcacttc gttgaccgtg gacccaacga atattacaga tggaggaaac ataaaagtaa
      121 aattctcgtt tgacgaaaaa aaacaaaata tccaaccagg tgattatctt tggatcaatt
      181 ggccaagtga aggaaatatt cgcggtgaag gattccaaaa agaaatccca ttaatgattg
      241 aaaataaaaa tgttggaact ttaacggtca gaaaagattc tgcgcaggtt gtgtttaatg
      301 aaaatattaa aaacctagac tcagtagaag gttgggggca atttgagata caggccagaa
      361 acgtaaccga taccggtgaa gaaaatacgg gaccattcac cgtgacgagc ggtgataaaa
      421 cagctactgt aaatgtgaca aagccagctt ctggttcttc ttctagcgtt ttttattata
      481 aaacaggaga catgctacct gaagatacta agcacattcg atggtttttg aatattaaca
      541 ataacggcac ttatgttgaa caaccagtta aaatcagtga tgaaatccaa agtggacaaa
      601 gattagatcc aagtacgttt gaaattaatc aaatacactt aggtgaacag aaggtttata
      661 gaggagaaga gggaatccaa caatttttac aagatttccc cagcgctaca tttaattttt
      721 cagtaactga taattacatt gaaataacta taccaaaaaa ctttgtcaat cttaggaaaa
      781 taatggtgag ttataagacg atcatagaaa acccagaaca aataaatttt gagaatcatt
      841 cggaagcttg gtttaaagaa tttaataaac ctgctgttga tggagaaagt ttcaatcata
      901 cagttaaaaa tatttcagct tctggtggag tcaacggtac agttagaggc gaattgaaga
      961 ttttcaaata tatcaatgac acagagattg gtatcccaaa tgtgactttc gaattaagac
     1021 gagcagatga acagcctatt caaggacagt ctagtatcct gttgacttcg aatgaacagg
     1081 gagaagctag tatcaaaggc ctgcaagtag gagactatgt tgtaaaagaa aaagaagcac
     1141 ccaattggat tgattttgat ccactaagtt caaatgaact caaattctcc ataaacgaaa
     1201 atgatacaga gggagtcagt ttacctattt ataacaagaa aaaggttacg aacatcacag
     1261 caactaaaat ttggaacggt ggaaccactc caagaccgag tatttatttt aaattattca
     1321 gagcaagtac aaacaattgg gaaccagttc ctgatgcaga aacaaaacga ttagacaatg
     1381 gaataacttc agtgacttgg gaagatatcc aacagtatga tgatagtgga aacgaatata
     1441 cgtttaaagt gcaagaagta gatcaaaacg gaaatgatta tgtcccttca ggttatcaaa
     1501 aaattgaaaa cgggctagtc gttacaaatg agaataaaga agtcatttca gtctcaggac
     1561 aaaaaacatg ggaagacaat gagaaccaag acggcaaacg accgacgacg atcacagtaa
     1621 atctattagc cgacggtcaa ccgatccaac acaaagaagt aagtgaaaaa gatgattggc
     1681 gctatcgttt cacaaatctg ccaaaataca gagacgggca agaaatcatc tatactgtaa
     1741 cggaagacaa cgtgcccgaa tacagtacga cgattgacgg gtataacatc aaaaacagtt
     1801 atacaccgga aaaaacaaat atatctatac caggtagcca tataacaccg tggaaaaatt
     1861 ttccagagaa gacagagaga gagaaaatta gaaatctatt ctctcaaaaa ttgcaaatat
     1921 ttgctcatac aggagaatcc agcgaacaaa gaagcaatta tattagtaag agagctgtac
     1981 ctaaacagat aacaaataaa tcaaaaagca ttcttcctaa aacaagtagt aaaaaatcta
     2041 gttttgctgt aatcattggt ttattgatag taactatctg tgctgggata ttcttacaaa
     2101 aatataaaaa agtttagtta gaatataata ttttttgtta aatatgactg aaatcaaaag
     2161 aataaaattc cgatttataa tcgaaaaaag aagcattttt atatatgctt cttttttcgt
     2221 agaatcaata aatatggatt tggctaacta tggaagaata ctcgtattag ttttcagcgt
     2281 tcatactagt tgttacattg tttgattggc caaaagaatt tctgatatat tttgtgctaa
     2341 ataaagaaaa agacgcttga attgggaaat aagaaaacta ctctatcatt acaaattttc
     2401 ataaactggc agatgttcta agtaaacaag tatcttttca aagtcggaaa aatccataat
     2461 caacgtagtg gtattgatat ttggatgaaa gcctacggta tcttgacgat caatagcagc
     2521 atcgatcacg acttggattt ttttctcttt gtcgtgcatc aatgctaatg gagtcactgt
     2581 acctgctgga acgcctagga ggtcaggaag ctgttcttca gaaacaaaag ataagcgctt
     2641 ttcttttaat tgttcagcta gttgttttaa atcggcgtgc ttttcatcag gcaagatgac
     2701 aagatagatt tgttttcctt ttcttgattt caataataga ttttttactt gcggaccagg
     2761 tagggaaaaa gggacatttt tgactgacgt aatcgcagga tgatcgactt tttgaaaaga
     2821 gatacccagt ttttttagta gttcataagc ttcttgttcg gttgcacgac tcatcgcgca
     2881 tcaccctcct ttttttatta gtgtatcata aaaaagagtt gacaaatgaa aaataatcat
     2941 gtaaattaca cgtaaagtta aaacaaatga catcgaaaag aagagtagcc gttaggtgtt
     3001 tttagagagt ctctggttgg tggaaagagg cagcagttaa ccgtgaaaca catcttggag
     3061 tcgattttct gaagcgtata gtaggaaaat ccggggagcc cgttacagct gcggtcgttg
     3121 ctagatgacc agataaggct ggcttttccg tgaggagtcg gtaaaaaaag gtggaaccac
     3181 gtgattaacg tcctttgatc ttcggatcaa aggacttttt gttttcatct gaacggcaac
     3241 gactgtgtga ggttttttct gcaaggaaaa aataaacaga ggtggaacca cgtataatac
     3301 gtcctcttgg catttgccaa gaggattttt ttattttaaa ggaggaaaag aagatggagt
     3361 atttgattga agttatgccg caattattag taggagcact cacaacattg aaattatttt
     3421 tatttacctt gattggctca ttaccattag ggattgtttt agcattagga ttgtctttgc
     3481 attttaagcc gctacgctac ttgcttcaaa catatgtatg ggttatgcgg ggaacaccgc
     3541 tgttgttgca actgattttt attttttatg ggttgccgac gattgggatc gtttttgatc
     3601 gtttcgaagc agcactcatt gcctttatct taaactatgc agcttatttt gcagagatct
     3661 ttcgtggagg gatacaatcg attcctcaag gtcaatatga agcagcgcaa gttttgcaat
     3721 taagtccctt tcaaacggtg acgaaaatcg tcatcccaca agtgacaaag attgttttac
     3781 cttctgtagg gaatgaagtt atcaacttgg tcaaagattc ttccttgatc tatatattag
     3841 gtttaggtga cgtaatgcgt gctgggaaaa tcgcgatgga acgcgacgcg actttactgc
     3901 ctttgctagg cgtggcaatc atctatctta cattgactgg tattctaaca atcataatga
     3961 aacaagttga aggaaaatta aattattacc gctaactgat aggaggaaga aatatgattg
     4021 aattgaagaa agtgaacaaa gcatttggtg aaaaaaaaat aatcaaagat ttgaatctaa
     4081 tcattccaga tgggaaaaca ttagctatcg taggtccttc cggtggcggt aaaaccacgc
     4141 ttttacgtat cttggctggc ttagaaagtt ctgacagcgg agaattttat ttagacggtg
     4201 taccgttcaa cccattcgag cttaaaatga aagaacaagt tgtaggagtc gtattccaag
     4261 acttccagct atttccacat ctgaatattt ttgaaaacat taccttagca ccaaaaatgg
     4321 tattgaaaca gacaaaagaa gaatacacca aaaaagcaga agaattagcg gcttcattag
     4381 ggattagtga tttattgaat atctatcctt atcagctttc tggcggacaa aaacagcggg
     4441 tagctattgc cagagcattg gctatgaatc cacgggtatt ggcttatgat gaaccaacaa
     4501 gtgctttaga tcctgaatta cgccagcaag tcgagcgttt gatcctatca ttgaaagaag
     4561 atggggtaac ccaaattatt gtcacccatg atttagtatt tgcagaaaat gtcggtgatc
     4621 aattactaaa agtttcccca attcattaag aaaggagaag atagagatga aaaaaaccag
     4681 ttttctattc gctttgatcg caggtcttct tctttttgca ggctgttcga acaaaaaaac
     4741 ttcagcagat aattgggcga ctatcaacga agagaaaaaa atcgttatag gtttagacga
     4801 tacatttgtt cctatgggat ttagagataa agacgggaag ctcacaggat ttgatattga
     4861 tttagccaaa gcagtctttg aacaatatgg gattacggta gactttcagc ccattgactg
     4921 gtcaatgaag gaatttgaac tgaacaatgg aacgatcgat ttgatatgga acggctattc
     4981 caaaacgccg gcaagagaaa agaaagtgca atttacaaaa ccttatatgg aaaacgatca
     5041 agtgctgatc acacctaaag aatcaggaat cacaaacttt ggacaaatga ataataagag
     5101 attaggtgcg caaaatgggt catctggtta tgatgtattt acgaaacaac cagaagtatt
     5161 aaaagagata gtcaaaaacc aagatgctgt tttgtatgat agttttaatg aagcattgat
     5221 cgatctgaaa agcagacggg tcgatggtct gctgatggat aaagtatacg cagactatta
     5281 tttgaaacaa agaaacgaac tagaagactt caacataaca aaaggttctt atgagagtga
     5341 ggattttgca gttggtgcac gcaagtcaga tagtacatta gtgaaaaaaa tcaatgaagc
     5401 cctagatcaa ctagagaaaa caggtgaatt ccaaaaaata tccgataaat ggtttggcga
     5461 agatgttacg ccgagaaatt aacaaatagg ggactgtgac aaaagacgtg tcacagtccc
     5521 tttttccgaa taaacagtgt tctcctgcca actccttgtg actcggagct gaatggcagg
     5581 ctcacaacct cttggtaaac ggtgttcaaa agccagtttt tcggtattaa gccaaattta
     5641 tgcaaaaatg tagaaagcca ttttcacaaa atttttctta ctactcgaaa ctaagcgact
     5701 ttttcacaac ctcctttaca taattttatt ttgttgtgga aggggtttcg tgttattcta
     5761 aaagaggaac gattgaaggt tataggaaag gaagagatga atggaacaca aagaacttac
     5821 ctcatttcca aaagattttc tgtggggctc tgcttctgca gcgtatcaag tagaaggagc
     5881 ttggcaagaa gatgggaaag gagaatcagt ctgggatcga tttgtacgga tacctggaaa
     5941 gacatttaaa ggaacgaacg gtgatttggc agtagaccac tatcatcgtt ataaagaaga
     6001 tattgcttta atgaaagaac aaggtctgaa agcttaccgc ttctctgtag cttggacacg
     6061 gatttttcct aatggacgag gagaagtcaa tcaagctggg ctcgcttttt atgagagatt
     6121 gatcgacgaa ttgattgaaa acgatattga acctatgttg actttatatc attgggatct
     6181 tccacaagca ttgcaagatg aatataatgg ttgggaatca cgtcagatca ttgaagattt
     6241 cactcattat gcagaaacat tatttgaggc attccgcggg aaagtccatt actggattag
     6301 tttgaatgaa caaaatatct tcacttcatt aggttatttg ttagcagcac atccgccagg
     6361 tgtgacagac ccgaaacgaa tgtatgaagt taaccatatt gctaatttag caaatgcatc
     6421 tgtcatcaat aaatttcacg agttagaaat gcctggaaaa atcggaccaa gctttgcgta
     6481 tacgccaaat tatccaattg acagtaatcc tgaaaatgtt ctggctgctg aaaatgcaga
     6541 agacctgatg gccaattatt ggatggatgt ctatatgtgg ggaaaatatc cgattgctgc
     6601 catgaggttc ttagaagaaa aaggatgggc accaacgatt gaagctggcg atgcagaatt
     6661 gctagaatct gctaaaccag attttcttgg gatcaattac tatcaaacgg cgacgaatgc
     6721 attcaatcca ttaaacggag ttggtgctgg aaaaatgaat acgacaggaa aaaaaggttc
     6781 atcagaagaa actggagttc ctggaatgta taaaaaagtt gagaatccat ttgtcgaacg
     6841 aacaaattgg gactgggaga ttgacccaga aggattaagg atcggactgc gtcgtatcac
     6901 aagccgttac cgcatgccgg tactgattac ggaaaatggc ttaggagagt atgacaagtt
     6961 gacagaagat aaacaaatcc atgacgacta tcgaatcaat tacttacaaa gccacgtcaa
     7021 agccatcaaa gaagcaattt cggatggagc agaagtccta ggctattgca cctggtctta
     7081 tacagatttg cttagctggc tgaacggtta tcaaaagcga tatggatttg tatatgttga
     7141 tcaagacgaa acacaagaag gatctttgga acgatataag aaagacagtt attactggta
     7201 ccaaaaactg attgaagaaa atggagagaa cctttagttc acatacttaa aacaagaagg
     7261 tacggctgga tatggccgtg ccttttcttg ataaaatcat ttagaaatta agaaaaactg
     7321 taaaataagc tgaaaaatga aagaaagcgt cagttctttc aaacaaaact ttagttccct
     7381 tacttttttt tgtataatga aacttgatga aatgagggat aataaatggc acaaaagaaa
     7441 cggcctacta aaaaaaggaa aaagacgaaa aaaacgaaaa agcaaaaaca gcagcaggaa
     7501 caaatgctga cgattggtgt tgggtttgcc ttgattttat ttgctgtctt cggcttttta
     7561 aaattaggtt ttttaggaat attgattgca aacggctttc ggatcattgc aggaaatact
     7621 taccaaatcc tctgtctttt attagccgta ttaggatttt ggattgtcat taagaataca
     7681 gagttttcaa ttggtaaaaa ccgacgctgg tttggcggca tactctttta tttcggtatc
     7741 ttattattgt tacatgccca tttatttggc aaactccata ctggggaacc aaatatcatg
     7801 gggacgacat gggatttgtt agccagtgat ataaaacaaa gtcaagtaga caataacgtt
     7861 ggtggtggga tgattggagc aatcctttat cattttactt acttcttgat tgcacagcct
     7921 ggaagttatt tagcagcagt gctattactg gcaggaggag cattcctgtt cagtaatctg
     7981 gaaggctatc agctgttaaa tggtatccaa tcaattggag aacgagtaca ggaattattg
     8041 gaaggtgatc ctgccaagca agctcgaaag caagcggcaa aggaagagag aatgaaacag
     8101 cgcgcagaag cgaaagaagc aaggcgctta gctgcaaaag aagctgcaga aaaagaagct
     8161 gcagaatatg agaagaaaaa agcggtgagc cagcaaaggg aaaatactgc tgatgaatgg
     8221 caggaaccag aaaatacaga gccggagcag ctaagttttg ttccaatcga cagttttcaa
     8281 gaaaatatcc atcctgcgaa tctagagaaa ccagtaccag atacaccaaa acagaccaat
     8341 acagcagaag gtttttcaga tgagttgcca gaggatgacg gtacctcatt agaatttgag
     8401 attgaagcag aacaggaaaa tcaagactat gaattaccga cagttgattt gcttgattct
     8461 ataccaactg tggatcaaag tgatgagtat aaaaaaattg aaaaaaatat cggcgtatta
     8521 gaacaaactt tccaaagttt cggtgtcgat gccaaggtcg tcaaagccag cttaggacca
     8581 tccgtcacaa aattcgaagt ccagccggct gtaggggtaa aagtaagtaa aattgtgaac
     8641 ttaacagatg atatcgcgct tgctttagcg gcgaaagatg tccggatgga agcaccgatt
     8701 ccaggtaaat cactgattgg tattgaagta ccaaatggaa agatcagtat ggtttccttt
     8761 agagaaatca tcgaagcaca accaaaccac ccagataaat tactagaagt acctttagga
     8821 cgtgatgttt ctggacgggt acaaacggct gatctttcga agatgcctca cttactcgtg
     8881 gctggttcga ctggtagtgg gaagtcagta gcaattaatg ggattatcac aagtatatta
     8941 atgcgtgcta agccccatga agtaaaactg atgatgatcg atccgaaaat ggttgaattg
     9001 aatatgtaca acggcatacc tcatctgttg acgccggtcg tgacgaaccc tagaaaagca
     9061 gcgcaagcct tacaaaaagt agtacaagaa atggaagaac gatatgaaaa attcgcggca
     9121 accggagtaa gaaatatttc tggttacaat gaatttgttc aacagaaaaa cttggaaaac
     9181 ggaacgaaac atccaacctt accattcatc gtagtgatcg tagatgaatt agctgatttg
     9241 atgatggtag ccagcaatga agttgaagat gcgattattc gtttagcgca aatggctcgg
     9301 gcagcgggga ttcatatgat cctagctact caacgtccaa gtgtggatgt tatcacagga
     9361 atcatcaaag caaatgtacc ttccagaatg gcatttgcgg tatcaagcgg tacagattct
     9421 cggacgatca ttgattctaa tggggcagaa aagctcttag ggcgaggaga tatgctattc
     9481 ttgccaatgg gtgagaataa accgatccgt gtgcaaggag cattcatttc tgaccacgaa
     9541 gtagaacggg tcgttcaatt tgttacagat cagcaagaag ctcattatga agagaaaatg
     9601 atgccgacag atgaagttga aacgacaggt gctccagaac agccacaaga tgagctgttt
     9661 gaagaagcaa aagcacttgt cgttgaaatg caaacggcaa gtatttccct tctccaaaga
     9721 agatttcgga tcggttacaa ccgagcagca cgtttagtag atgaactgga agctcatgga
     9781 gttgttggcc cgtcagaagg aagcaagcct cggaaagtat tcattgagca ggaagaaaca
     9841 tcagaaacgt tgccggacga taatgacatg taaaacttgt gtgatgaagg gttgaaaaac
     9901 gaataaccaa taaaaagaca aggcatgatg ataccaaaag aaaaaatggt ttttttccat
     9961 cttttctaat acggtatgat gtcttgtctt tttagttttt gtgagattaa agttctattc
    10021 gatttatttg tgaagtattg cattaaggaa atgaatcatg tatagtatgt agcgaaactt
    10081 tgagaaaaag agggaaaata ctttggaaaa acagtccatt tatggcttga cgaatgaaga
    10141 attaatcaat tggtttatag aaaacggcga gaaaaaattc cgagctgccc aagtttggga
    10201 atggttgtat caaaaacgtg taagtaattt cacagaaatg acgaatctat cgaaacaatt
    10261 gatcgaaaaa ttatcggagc attttatcat caatcctcta aaacagatgg tcgtccaaga
    10321 agcttcggat ggtacagtaa aatatttgtt tgaactccct gataaaaaca tgattgagac
    10381 tgtactgatg agacaagaat atggcttgtc agtttgtgtg acgacacaag taggatgtaa
    10441 tatcggctgt acgttttgtg caagcgggct gctcaaaaag aaccgtgatc tgactgctgg
    10501 agaaattgtt gcacagatca tgatggtcca acattatttt gatgagcgca atcttggcga
    10561 acgcgtttca catgtcgttg taatggggat cggtgagcca tttgataatt acgacaatgt
    10621 aatggacttt ttgcatatca tcaatgatgc caaaggattg gcaattggtg ctcggcacat
    10681 tacagtttcc actagtggat tagcacacaa aatcaaggaa ttcgctaata acggcttgca
    10741 agtcaatctg gctatttcct tgcacgcgcc gaataatgag gtgcgaacat cgatcatgcg
    10801 gatcaaccga agtttcccaa ttgagaaatt gatggaagct gtggatgagt atttagagaa
    10861 aacaaaccgt cgaatcacgt ttgaatatat catgttgaat caagtaaatg atagaccaga
    10921 gcatgcgcaa caattagcag atctattaaa agataagaaa aaattagcat atgtcaactt
    10981 gattccatat aatccagtca gtgaacatga tcaatattct cgcagtccaa aagctgatgt
    11041 attgagattt tatgatgtat tgaagaaaaa cggcgtaaac tgtgtgatac gtaaagaaca
    11101 tggtacagat attgatgcag cttgcggaca attgcgaagc aagcaaatga aaaaaacagt
    11161 tgccaaataa tcgtatccta ctcgtttttt caattaccat aaaaggagca gttttcttaa
    11221 ttaaggaact gttcaactta aataagagaa aagattctat agcgaaagct ataaagcttt
    11281 ttttgacaag aaaaaccctc atcaagcaaa gaaatgtcct caatttgatg acagcctgct
    11341 tgatgggggt tttagcaatt atttaactga ttttcttata tccttgctgg ctttcttgtg
    11401 tagcatgata agtttctacg tcaagaatgg cctgtttaaa tttttctcgg gtgatttcat
    11461 aaggcacatg tttaatatca tttgttgcca tggctttatc taagattgct tctaaatcgg
    11521 tcgtgacatt gagattcatg tcggttaacg atactggaag ttggttcttt ttcataaaca
    11581 catagatttt atcaaacaaa tcgaactgct gatccatcat caataaggtc agtacaccat
    11641 aactgacaga tgctccgtga aggtatccct ccattttttc tagaacagtc gtaccgtaat
    11701 agaatgagtg tgccatagca gaattatagt tattgttaac taaaacagaa accaatccgg
    11761 tagtaacaat gatatccgaa acgacttgtt caattgcata tgagggacga tcgtcggcac
    11821 tatctttcaa tgcttgcgta ccataagtca agagacgatc aatgcacatt tttccgattt
    11881 ggattcctaa tctatccgtg tagcctagat catcgccacg agcagaaaaa gtagattcga
    11941 cttctttgga taaagcatcg ccaatacctg cccataagta tttatcaggt gcttcggcaa
    12001 taattgctgt atcaatgaag gtgtgtacag gtggttttga aggaaagaag agtccgtcca
    12061 ttacgccttc ttcgttatag atgacacata ccgcagtgac gggcgaacag ttcgaaccaa
    12121 tagtgggaaa ggtgaagact ggtttagcta gtttttcacc aatgactttt acagtatcgc
    12181 aagcacggcc accaccgact gcaaacagga cgtctgcttt ttggacactt tcatgctgga
    12241 tcaactgttc aatatttcca taagttgaat tacccccgta ccagagactg gcgacaacct
    12301 ctatttcctg tgtcaaagct acttttattt tgttttctgc ctttgaaagt gcagtcttcc
    12361 ctccaatcag cactactttt gtcccatatt ctttgacgat tccatttgct ttttcatacg
    12421 catctgttcc aatggtataa tttggtaaga aaacactttg actcatattc atttccttct
    12481 ttcttcgttg aaacgggtta aaattttaaa gagtgatcga tctgactgcg gctgtagatg
    12541 gagtagaggt gaacctaaga caggataagt gatgaataag gtggcatgaa caccttgaaa
    12601 tcatcaataa gtatcctaaa aacgaacaag tacaaaaaca ttgaaaacga caataatgaa
    12661 tttttgttcc tcttagtatt tctaccgatt ccctttgctt ttttgtaatt atctaaaaat
    12721 tctaaaaatt aagattatta tatgaaaaca ggttttattt gtcaattcat aattggtttt
    12781 ttttaaagca aaagataatc tatatcatga tgaacaaaca gagttttttc ctccaattga
    12841 tggctttcct gatctttcct attttgaata aagtgtttct gtataatttt tttattttat
    12901 aagtaagata aataatgaaa gaatagagat actgattggt agctaaagat ttttgagcga
    12961 gaacatttcg ttttttcaaa aggactgtta gaataagcaa gaacaagggg gaagacgtat
    13021 gataatcagt gaatttgacc gtaataatcc agtattgaaa gatcagcttt ctgatttact
    13081 gagactgact tggccggaag aatatggaga cagctcggca gaagaagtag aagaaatgat
    13141 gaatccagaa cgaatcgcgg tagcagcggt agaccaagat gagttagtag gatttattgg
    13201 tgcaatccct caatacggta tcacaggttg ggaattgcat ccattagttg tagaaagctc
    13261 ccgacgaaag aaccaaatag gtactcgatt agtcaattac ttagaaaaag aagtagcttc
    13321 cagaggagga atcacgattt atttaggtac ggatgattta gaccatggaa caacgttaag
    13381 tcaaacggac ctgtatgagc atacatttga taaagtggct tccatccaga accttcgtga
    13441 acatccgtat gaattctatg aaaaattagg ttataaaatc gtaggtgtct taccaaatgc
    13501 aaatggctgg gacaaaccgg atatttggat ggcaaaaacg attattcctc gaccaaattc
    13561 tcaataataa aaagaggttg tgacagaagt aatcagcttc aagaaataag aaggaattta
    13621 cgaaaattac ttcttgaatt tttgtgaaat tccaacttat ttccgaagaa gctacttttg
    13681 gaacaccgtg tacc
//
LOCUS       DAZKCH010000071        13427 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000071 DAZKCH010000000
VERSION     DAZKCH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.072"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..912)
                     /locus_tag="ACG84X_002167"
     CDS             complement(<1..912)
                     /locus_tag="ACG84X_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFP9128001.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1340..1903
                     /gene="efp"
                     /locus_tag="ACG84X_002168"
     CDS             1340..1903
                     /gene="efp"
                     /locus_tag="ACG84X_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFP9128002.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2004..2174
                     /locus_tag="ACG84X_002169"
     CDS             2004..2174
                     /locus_tag="ACG84X_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128003.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2389..3648
                     /gene="lysA"
                     /locus_tag="ACG84X_002170"
     CDS             2389..3648
                     /gene="lysA"
                     /locus_tag="ACG84X_002170"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFP9128004.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3635..4435
                     /gene="dapF"
                     /locus_tag="ACG84X_002171"
     CDS             3635..4435
                     /gene="dapF"
                     /locus_tag="ACG84X_002171"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFP9128005.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4438..5319
                     /gene="dapA"
                     /locus_tag="ACG84X_002172"
     CDS             4438..5319
                     /gene="dapA"
                     /locus_tag="ACG84X_002172"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFP9128006.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5316..6032
                     /gene="dapB"
                     /locus_tag="ACG84X_002173"
     CDS             5316..6032
                     /gene="dapB"
                     /locus_tag="ACG84X_002173"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFP9128007.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6038..6733
                     /gene="dapD"
                     /locus_tag="ACG84X_002174"
     CDS             6038..6733
                     /gene="dapD"
                     /locus_tag="ACG84X_002174"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFP9128008.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6749..7750
                     /locus_tag="ACG84X_002175"
     CDS             6749..7750
                     /locus_tag="ACG84X_002175"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFP9128009.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7747..9108
                     /locus_tag="ACG84X_002176"
     CDS             7747..9108
                     /locus_tag="ACG84X_002176"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFP9128010.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9068..10219
                     /locus_tag="ACG84X_002177"
     CDS             9068..10219
                     /locus_tag="ACG84X_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFP9128011.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10194..11363
                     /locus_tag="ACG84X_002178"
     CDS             10194..11363
                     /locus_tag="ACG84X_002178"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFP9128012.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11538..12917
                     /locus_tag="ACG84X_002179"
     CDS             11538..12917
                     /locus_tag="ACG84X_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9128013.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13198..13427
                     /locus_tag="ACG84X_002180"
                     /pseudo
     CDS             13198..13427
                     /locus_tag="ACG84X_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4482 a         2339 c         2924 g         3682 t
ORIGIN      
        1 gtaaatgttt tttgataaat agcggtctgc tgcgtctgga aaaatcgtaa cgacacgatg
       61 accaggtggt aaacgacgaa tttctcttaa tgctgctgca aaagccgcac cactcgaact
      121 tccaactaat agtccttgtt ctcgtgctaa ctgcctagta tagttaaacc cttctacatc
      181 agagattgtc tcgatctgat tgattgaaag gggagaaaga aacggcggaa tgaattctac
      241 accgataccc tcaatttcgt gaggggctgg atcaccacca tttaacacag agccctctgg
      301 ttctacaccg attattcgaa tgtcgggata tttttctttc aaaaaggtag aagttccagc
      361 aaaggttcca ccactcccaa ttcctgctac aaaactatgg atattttctt tgatttcatg
      421 aaagatttct ggccctaacg tatgatagta agcagcagga ttatctttat tttcaaattg
      481 aagaggcaga tagctgtttg atatctcctc tgcaagtttt ttacttttgc tgatggcacc
      541 gatgattcct tgctcactag gagaatggat gatctttgct cccaatgctt tcatcaattg
      601 ttgtttttct aagctaaact tctctggaac aacaaaaacc gttcttaatt tgtatgtgag
      661 tgcggccaga gcgatcccaa ttcctgtatt tccggcagtt ggttcgatga tcgtcgtttt
      721 ttcattgatt tttccttggg caaatccttc tttgatcaaa taactgccca atctatcttt
      781 gatacttcct ccaggattta aatattctag ttttgcataa atagcagaac ctttaggcat
      841 agaatagtgc tgattgtcaa agcgataaag cggtgtggaa ccaatagctt ctgtaattgt
      901 cgagataatc atgtgggcct cctaaaaaaa gataataaaa aaaggagctg actattaaat
      961 cagctccttg aaagacatag agaaaaattg agtagataaa aagataagtt acctggtact
     1021 cattctatga agggcaatta atagacatga caaatagtat gctgctttta tgcaccatac
     1081 aacagcaacg attcaattgt ttttggttgc tgactgtcat gtgtatccct ccaagtaaaa
     1141 tttttattaa cgatagcatg aaaaaaaata aaagtcaaag gcttgaaaga aaaaaatatt
     1201 tcgatagcat cgtttacccg tgtttatttt tctgacaaat aggcatgaga ccttaaaaga
     1261 tagagaatac tctagttttc tggccggttg tctgatacaa taaagttgat tatgataaag
     1321 aaaagaagga gcaaaaataa tgatctcagc aagtgattta agagccggta tgactttcgt
     1381 acaagacggc aaactgatta aagttctgga tgcaagccac cataaacctg gtaaaggaaa
     1441 tacagttatg cgtatgaaac tgaaagatgt ccgttcaggt gcaacatacg acacaacgtt
     1501 cagaccagaa gaaaaatttg aaaaagcaca tatcgacaca aaacctgtac aatatttgta
     1561 cacgatggat gatacagctt tcttcatgga tttggaaaca tatgagcaat atgaaattcc
     1621 tgtagaaaca gtagaagaag aaatgaaata tatcctagaa aacatggaag taaaaatcca
     1681 atttttcggt agcgaagtca tcggcgttca attaccaaca actgtcgtat tacgtgttgt
     1741 ggaaacacaa ccttccatca aaggtgcaac agtcactggt tcaggtaagc cagcgacaat
     1801 ggaaactggc ttagtagtca atgttcctga cttcatcgaa acagatgaat tgttggaaat
     1861 caatacagca gaaggttctt atgtaaaacg tgcgtcaaaa taattcgcta acggattgat
     1921 aagaatttga aaacagagct tgacctcttg aaaggcagat catcggatct gcctttcaag
     1981 aggttttttg tggaatcagc aaattgaaaa ataaaaaagt atttgatttt atttatattt
     2041 tgaaagatga atggcaaaag ctagagaaag aaaaaactgc acttatttat gaagaaattg
     2101 aaatgattca taaaattgaa aatatccgaa ctattccgaa ctatattgaa gcgaaaatat
     2161 tttttcatca ctaaatagtg ttgaatttat gtttttatgt ataaatagct tctaatagtt
     2221 cgggtatttt gtttttataa ccatttttat tcttattttt aaaaaaatat ttcgaaatat
     2281 actagacaat tcagaaaatt ttgtttaata ttattccaat aaaattcaaa tctttatcaa
     2341 atgaaattcc aataaaaacg gaaaaaaagt gaaaagagga atgaaaaaat gacagaattg
     2401 ataattggcg gagtcacagc aagcacattg gcagaaaagt ataagacacc tctgtatgtg
     2461 tatgatgaag aaaagatgag acaaacgatg ctgtcattca agcgaggctt tgtatcgaaa
     2521 cgttttgata caaaagtgct ttacgcctct aaagcattcc aaacgattga gatgctgcat
     2581 ttagttcgtg aatatggatt cgggctagat gttgtcagtg gtggggaaat ctataccgct
     2641 ttgcaagctg attttcctag agatactatc tacttccatg gtaacaacaa gacgccagag
     2701 gaactgatct atgcacttga aaatgatttg ttgcatattg ttgccgataa tttgatggaa
     2761 gttgaattat tagcagaatt aagccaacgc tatttaaaaa aaatctgtat catgcttcgg
     2821 ttgaatgtcg gagtagaagc acatactcat gaatatatcg tcactgcgca tattgattca
     2881 aaattcggca tgagctatga aagtaaagag tgccaacaag cccttcagtt gataaaagaa
     2941 agcagctatc tagagttaga aggatttcat gctcatatcg ggtcacaaat ttttgatgtt
     3001 actgcttggt tagctgaaat cgacaaattg acgaattact taaccgattt tgaccaacct
     3061 ctttccttga atcttggcgg agggtttggg attcgttata cacaaaatga tcagccgatc
     3121 ccagtcgaag aggcactaaa aaaactgatt gaatatacgg aagaagcttt ggaaaaacga
     3181 aaactgacca ttcgtcaatt actgatcgaa ccgggtagaa gtattgttgg agaagctggt
     3241 acaacactat acacgattgg tttcatcaaa aagacaccac ataaaaaata ttactttgta
     3301 gatggcggga tgacagataa tatccgtcca gctctgtatc aggcagaata cgattgtgat
     3361 ttagcagcaa aactgtcgga agaaaaaaca gagaaagtga cgattgcagg aaaaatgtgt
     3421 gaatcaggcg atgtggtaat taaagaagct tatttgccga aagcagaatc gggtgatctt
     3481 ttagctgttt attccacggg agcttatgga tactcgatga gcagcaacta caatcgagcg
     3541 acacgaccag cagttgtttt tgtcaataat ggccaatcaa gactgattgt tcgcagacaa
     3601 gcattttctg atctactaag gggggaagtt tcctatgatc cttcataaat ataatggctg
     3661 cggaaatgat tttatcttat tagattacgc agaagacaca gattatagtc aattagccgc
     3721 ttctttatgc acaaaagaaa aatatgatat agacggattg atcgccgtaa aaatcgatcc
     3781 gttggaaatg atctattaca acaaagatgg cagccgcgcg ccgatgtgcg gaaatggcat
     3841 tcgctgtttt gctcgatacg taaatgatca gaacatgatg aatgaacagg aattcaacgt
     3901 agagacatta gcaggcacaa gaaaaattac ggtgttggat ccctcacctt tttattgcag
     3961 cgtagatatg ggagtgccag atgattctcc ggaaaaaatc aaagctaatc aaacttatcc
     4021 aataaaaaac caggaaatag agatcaatgg tgaaaaagta acgatcacta gtttattttt
     4081 aggaacgatt cataccgttg tttttgttga aaatgcgcgt gaggaagtct ggagaaaaag
     4141 aggtgaactg atctgtcatc atcctttgtt caaagaaaaa accaatgtca actttgtaga
     4201 agtagtcaat gaacaagaat tgatcgtccg tacctatgaa agaggagtag gttggacact
     4261 tgcttgcggt acaggttgct gtgcctctta tgtggttgct aaggaaactg ggaaaatttc
     4321 agcagatcag gtagttgttc acttggaaca aggagacttg atgatctctg gtgaggatgc
     4381 gatacaaatg gctggcccag cagttcatga atggacaaga atattggagg aatgaagatg
     4441 ataaaaggtt cgatcgtggc gctgatcacg ccgatgaatg aagagggatc agtagattat
     4501 gctggtttgg aaaaattgat ccaattccat ttagatgaac aaacagatgg attattagtt
     4561 ttaggtacaa caggagaatc ttctacgctc acacaatctg aggaggagca gatccttcaa
     4621 ctgacagtaa agaaagtggc tggccgtgtg ccggtgattg caggagctgg aacgaataat
     4681 acgaaagaaa cgattgaaaa agcgaagcat tttgcttctt tgggggcaga cgcacttttg
     4741 gtcatcaccc cttactacaa caaaacaagt gatgcaggac tagctgctca ttttacagca
     4801 attgcagaag cctcaccgat tccgcttatt ttgtataatg ttccttctag aacaggcatg
     4861 tcgattccaa tccatgtatt agtaaattta gcagaacatc ctaatatcat tggtttgaaa
     4921 gaagcctcag gagatatggc ttatgtgatg gatgccgctc ggttgattgg agaagaattc
     4981 ttcctttaca gtggaaatga tgatttgatc ctaccagtaa tgagtgtagg aggaagcggt
     5041 gtaataagtg tatgggcgaa tatccaacct aaaatagtcc atgaattagt aaaagatacg
     5101 caggacggaa gatggcagca agcaaaagaa aagcaattaa atgcacttga actgatccat
     5161 gccttgttca gtgagaccaa tcctattcct gtcaaagcag ccatgtcatt attagactta
     5221 ccttccggac ctctacgcct gcctttagtt tctctttcaa aagagaaaaa gaaacaatta
     5281 gctcagcttt tgttaaaaga aaggacggtt gaaaaatgaa aatcggactg attggcagtg
     5341 gacagatggg aaatagagtc gaagaagttg cacaagaaag aggagatacg gtccttcttt
     5401 tacggacggc acctaaagaa gcaactacgc ttgcttttac ggaactgcca gaactgctta
     5461 ttgatttttc tcatccagat aatttagaga aaatcctttc gtatagctta tcatatcaac
     5521 ttccgttagt cattggcacg acaggttata cacaatcaca gttccaagaa ataaaagaac
     5581 atgccaaaca tgtacctgtg atgtatagtg ctaatttttc gttcggcatc atggtgatga
     5641 atcaactaat caagcaagca gctgcaatgt tgcaaggctg gcagatcgaa ctgattgaaa
     5701 aacatcatag tcgtaaaaaa gatgcaccat ctggtactgc aaatatgctg cttcaaacaa
     5761 tccaagaagt gcaaaagctg cagcccgtat acaactggca agggaaaaaa agagaagaaa
     5821 accaaattgg tgtacacagt attcgtgcag gttctttacc tggtgaacat gatgtattgt
     5881 ttgctgctac tgatgaaata tttacgatca aacatgaatc tttttctaat cgaatctttg
     5941 ctgcaggcgc agtagaagca gcggactggt tgaaagatca gtcaccaggt tattacaaat
     6001 tagaagattt attaatggac aaaggggtgt aaaaaacgtg gaagctcaag aaatcatccg
     6061 ctacattcaa acggcatcta aaaagacgcc tgtgaaagtc tatctgaatg taaccgagcc
     6121 aatcgaattt aaagaaagta aagtttttgg tgaaggaagc agcttcgttg tttttggtga
     6181 ctatgagacg attgctccgg ttttagaagc tgaatcagaa aaaatcattg aaatcgaaat
     6241 cgaaactgct gcaagataca gcgcagttcc tttgctagat attaaaaaaa ttaatgctcg
     6301 tatcgaacca ggtgctatta tcagagatca agtgtcaatc ggcaacaatg ccgtgatcat
     6361 gatgggagcg attatcaata ttggtgcagt aatcggtgaa aacacgatga ttgatatggg
     6421 tgctgtctta ggtggacgag cgacagtggg caaaaactgc catattggtg caggagctgt
     6481 cttagcaggt gtgatcgaac cagcatcggc caaaccggtt atcgtagaag acggcgtact
     6541 ggtaggtgcg aatgcagtga ttgttgaagg tgtccatatc ggaaaagatg cagtcgtggc
     6601 agcaggagca gtggttttag aagatgtggc agcagaaact gttgtcggtg gaatacctgc
     6661 acgtgtatta aaaataagtg atgatcagac aaaagaaaat acagcattga ttgctgcgtt
     6721 acgcgaatta tagaggagat ggagaaaaat gcgcgaaata gatacctgta ttgtgggggc
     6781 aaccggatta gtcggccaaa cgatgctcaa agtgttagaa gaatatgatt ttccagtagg
     6841 acgattgaaa ttattagctt caaaacgttc agccggtaaa gtttgtgtat tcaagaaaaa
     6901 gaaacacact gtacaggaat tgacagaaac ttcatttgaa ggatatgatt tagcgctatt
     6961 ttctgcaggt gcttctgtat ccaaagagtt tgcgccaatc gcacgaagtc agggactatt
     7021 tgtcatagat aattcctcag catggcggga agattcggat attccattaa tcgttccaga
     7081 ggtcaatctg gaagactata cattgaatcg gctgattgca aatccaaatt gttcaaccat
     7141 tcaagcggta cttccgctta aagctttaca agaagccttt ggtatccagc gagtcaatta
     7201 ttcgacctat caagcagttt ctggttccgg gcaaaaaggc attgaagatc ttcatcgtac
     7261 gcaaaatgac gaggaaccag ttttgtatcc ttataatatt agccaaacgg tgattccgga
     7321 aatcgatcag cctttggaaa atgggtatac aaaagaagaa cagaaaatga taaatgagac
     7381 ccgtaagatt ctgcatcagc ctgctttgcc agtatcagca acctgcgtac gtgtgccaat
     7441 cgaaaatgga catggagtct ctgtggcagt tcaactgcaa aaagagttta cgacggaaga
     7501 aattagagag tgtctcagcc agtttccagg gattcaatta gaagatgatc tagcagcaca
     7561 taaatatccg acgagcattc ttgctagagg aacagatatg gtttatgttg ggaggatcag
     7621 aaaagacact tctttagaga acggattgtt gttctatacg actgccgata acatacgcaa
     7681 aggagccgct gcgaatgccg tacagattgc tgcagcttta atgcagaaaa tagcggaggt
     7741 ggcaagatga gtaatacgct gaaagtagcg aaattcggcg gaacatcgat gtctcatgaa
     7801 gagcaattca aaaaagtccg tacaattgtt ctttcagatc ccaatcgcca agtgatcgtt
     7861 gtttctgctt taggcaaacg tacgtcagat gatgacaaag taacagactt actttatttg
     7921 atttatgctt accttcagca tcatgttgat tggacacccc tttggaaaag gatttgtgat
     7981 cgtttcattc aagtaagaga tgttcttgcc ctgcagttac ctattgaaga tgaactagca
     8041 cgcatacaga aacaactgga agacgaaaag ataactgaag attatttagt aagtagaggt
     8101 gaatatctga ctgctcaact gatggctgag tatcttggtt accagtttat tgacgcaaaa
     8161 gacctgattt tctttgacta tgatgggaaa atcgatcagg aaaaaacagc acaggaaatc
     8221 acaaaagcat ttaaaagata tccgaaaatg gttgttccag ggttttacgg ggcgaaccct
     8281 gcaggaaaag aaaaattatt gggccgtggg ggaagcgaca ttaccggcgc gatactggcg
     8341 aagatgttgc aagcggaaag ttatgagaat tggacggatg tttcaggaat catgatggct
     8401 gatccgcgaa tcatcgatca tcctaaaatc atcgaggaaa tctcttttag agaactgaga
     8461 gagatggctt atatgggggc taacgttctt catgaagcag ctgttttccc agttcaagag
     8521 gctgatatcc ccatccaaat aaaaaatacc aatgatcctt tcgctcaagg gacaaaaata
     8581 tcgaatcacg aaatagaaaa ggaaaatgga ctgacaggaa tagctggacg caaggatttt
     8641 ctttccatca ctttattcaa acgtcatatg tccgatgaaa tcgggtttat ctggaaagca
     8701 atgagcattt ttgctaaaca tgagatatca atcgaacata ttccttcagg gatcgacaat
     8761 atcggagtga tcgtctcagc agaagcgatt gccgataagt tatttctcat cacgaaagaa
     8821 ttaaaagaaa cacttggcgt ggaagaaatc gtcgtgatcg aagacttagc tttgatctct
     8881 gtcgttgggg gtccgcataa agaattgatt ggattatctg ggaaagtgtt atcgatattg
     8941 aacaaattag aaattcgcac atcgatctta tcacaaggag cacaggagtt gaatctgatc
     9001 atcggtgtac cgaataatca atatgaaaca gtagtgaagg gtatctatga agggatggtg
     9061 aatacggatg ctgaaagaat atcgaatggc actccatcaa attcctgaaa tcgggtttca
     9121 tgaattcaag acaaaaaaat atttatatga acaagtaaaa aacagcgagg ccgttatcca
     9181 tgaaatcggc gaaacaggac tactccttta ttttgataat cagcaagaag aaacgattgc
     9241 ttttcgaaca gatatcgatg cactgccagt caaagaagaa acgaatctct cttttgcttc
     9301 taagcatgaa ggttatatgc atgcatgtgg tcatgacgga catatggcga tgcttttagg
     9361 gttgactgac tttataacta aacacattga ggatcttatt tataatgtag tactgatcta
     9421 tcagccatca gaagaaattt ccggtggcgc acaaagcgtt attcagtcag gattgttgga
     9481 taaatatgaa gtacaagcaa tatttggctt tcatctatgg cctggactag ctaagggaga
     9541 agttttctct cgaccaggac ctttgatggc acaaagcagt gaaacagaca ttatcattaa
     9601 aggccagtct gcacatattg cttctagtga aaaaggaatc gatagtctgg aggcagctgt
     9661 acgatttttg aagaatgttt atgattttga ccggcaatta ccggcagagt ggaatcatct
     9721 aatgaaattt ggccaaatcc aaggtggaac gatccgaaat gttttagctg gagaagttat
     9781 tgtatccgga agtatccgtt cttacagttc agatatgcaa aattatttga agaggggatt
     9841 agaccattta gcagaacagt ttcactctac agctactatt tcttttcgct ataatgacgg
     9901 ctatccagct gtaatcaacc atagaggctt atatgcagca ctgttagatt caaacaaact
     9961 acatgaatta gatgctccag ttcttcaagc cgaagatttt ggcatatata cgcaacaata
    10021 tccatgtgta tttttctttt taggtgtcgg tgatacccct gctttacatg atccgacgtt
    10081 cgattttgat atggatgttt tagaaaatgg tgtagaatgg tacaaaacga ttctttttac
    10141 agaaaatctt cttgtaaaaa tcgatagcag ttcaaaagag gagcgagtaa ataatgatga
    10201 atttatccaa tcgatttagt cctaggcttt ctagaataga agtatcaaaa atacgacaat
    10261 tcgatcagca aatatcgtcg ataccagatg tgatcaaact caccctggga gaaccggatt
    10321 ttccaactcc tgaacatgtc aagcaagcag gaatagcagc gattgaagaa gacttttctc
    10381 actataccgg aatgagagga ttagaggaac tgcgggaagc ggcttgtata tttcagcaac
    10441 agcgttatgg attaacttat gatccgcaaa cggaagtttt gacgacagtt ggtgcaacgg
    10501 aagcgattgc ctctgcgttg ttatctgttt tggaagaagg agacaaggtt cttattccag
    10561 cgcctgctta ttcaggatat cagccattag tggaactagc tggtgctgaa ttgatcccga
    10621 tagatacttc tgacacaggg tttgtctgtc agccggaaca atttgaacga gcatttgaac
    10681 aatatggatc agctgtcaaa gcagtcattt taaactatcc taacaatcct actgggacga
    10741 cattgtctgc aaaacaattg aaagcaatcg ctgaggtttt aaaaaaatat ccggtatttg
    10801 ttataagtga tgaagtatat gctgaattga cttatagtgg aacgcatatg tccatagcta
    10861 cttatcttcc agaacaaaca atcgtgataa gcgggttatc caagtcacat gcgatgactg
    10921 gttggcgagt gggctttatt tttgctcaaa aagcccttat tgacgaacta attaaagtcc
    10981 atcaatatct ggtgactgcc gctacaacga tgtcgcaaaa agctgcggct gaagcgctaa
    11041 taaatggggt gaaagatagc gagaatatga aagagcaata tcaaacacga agagactatc
    11101 tggtccagca attggcgcct ttaggatttg aagtgaccca gccaaacggt gcattttact
    11161 tgttttgcaa actcccagct gccattcaaa ctgactcttg gcagttttgt gtagaattag
    11221 cggaacaggc aaaagttgcg tgtatcccag gaattgcatt tggcccagaa ggagaaggtt
    11281 atatccggat ttcttatgct agcagcatgg aaaaattaca tgaggcctgc aaacggatca
    11341 aagacttttt aacagaacag tgattcatag attttatcaa aaaaacaatc gttaattttg
    11401 cggtatattc tgcaaggaga cgattgtttt ttaaatttag ttcaaatgaa cgcgtttctt
    11461 ttgattcata actaatgtaa tgttaagttt aaattgttta gaatgatttt aaaagaatat
    11521 tcaaggaggt ttcatcaatg gaaaaaatca aagttgtcat tgtaggtgca tctcatggag
    11581 ggcatcaatc gatcttggaa ctattgacac gatacggtga aaatgtagat atcacgctat
    11641 ttgaagcagg agactatatt tccttcatgt catgtggtat ggagctgtat ttagaagaca
    11701 aggtaacaga tgtaaatgat gtacgtaatt tcagaccaga aaactttccg caatccaatg
    11761 ttcatatttt aaataatcac gaagtaaaaa cgatcgatgc cgataaaaaa acagtaacgg
    11821 ttactagcgc atcagataac gaaacaaaag aatatcctta tgacaaattg attttgagtt
    11881 ctggtgtcaa accaaacaat ctgccagtac caggagcaga tctagaaaat gtctacttga
    11941 tgcgtggata caattgggca accaaaatca aagaaaaatt aaatgatccg gctattaaaa
    12001 aaatcgctgt cgtaggtgcg ggttacattg ggatcgaagc agcagaagca agccgaaaag
    12061 ctgggaaaga agtcgtattg cttgatgtga tcgatagacc tttaggcact tatttagatg
    12121 ctgagatgac agatatttta gaacaacacc taaatgaaaa cggtattgaa gttttgacaa
    12181 atgcaaaaat cgaagctttt actggtaacg gaaaagttga ggcaatcaaa acaagtgaaa
    12241 aagaaatccc agcagatcta gtcattcaag ctgccggtgt gaaggcaaat acagaatggt
    12301 taaaagggat cgtcgactta gatgaacgtg gctggatcca aacaaatgaa tacttgcaaa
    12361 cgaatcttcc agatgtgtat gcagtaggag atgctacact tgcttattct atcccagcac
    12421 gcaaaaaaat gccgatcgct ttagcgactg ttgcacgtag agaagcacgt tatgtagtaa
    12481 aacatctttt tgaagaagta ccaaacaaac cgttcggcgg agtcgtaggt tcctctgcat
    12541 taagtgtctt tgactatcat tttgcagcaa gcggattgaa tagctttaca gcagcaaaag
    12601 caggagtaga tgtacgagtg tcttattatg aagatacgtt acgaccaaaa tatgtaccag
    12661 aagaacaagg aaatccaaaa gtgtccatcc aattattctc ggatccaatg acccatcaat
    12721 tgctaggagg agcagtatta tctacctatg atgttacagg tcaaggaaat gtattggcac
    12781 tagcgatcca aaacaaactg actttagaag aactagcaga agctgacttc ttcttccagc
    12841 caggctttga ccgacaatgg agcatgttga atctagccgc tcaacaagcg ttaggagaag
    12901 aaccatttgt agaataagaa aacgaaatat ttgaaaagag gttgtgaaaa agctgccttg
    12961 catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttaac ttggctggac
    13021 ttattaccgc agatgcaagc ttttgaacac cgtttatttt caaaaaaggg actgtgacac
    13081 gatttgtgta ccgaccccca aaagttagac caaaaaatct aacttttgga ggtcggtatt
    13141 ttttatggtt aaatatactt ttgaacttaa attaaagatc gttcatgatt atttggatgg
    13201 caaaggcgat tggaccgtaa aaatccagat caagagattg aagcggaaat gcttaaaatt
    13261 cgggagaagc acaaggatta tggctgttta cggatgacca atgaactaag aaaccgcggt
    13321 ttctctatca ataaaaagaa agttcagcgc ttgatcaaga agctaggaat aaaagtaacg
    13381 gcatacacgc gtaaatcacg tcgctacaat tcttatcgag gaaaagt
//
LOCUS       DAZKCH010000072        13404 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000072 DAZKCH010000000
VERSION     DAZKCH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.073"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(64..606)
                     /locus_tag="ACG84X_002181"
     CDS             complement(64..606)
                     /locus_tag="ACG84X_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFP9128014.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            741..1130
                     /locus_tag="ACG84X_002182"
     CDS             741..1130
                     /locus_tag="ACG84X_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128015.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1134..1898
                     /locus_tag="ACG84X_002183"
     CDS             1134..1898
                     /locus_tag="ACG84X_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9128016.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2027..2974
                     /locus_tag="ACG84X_002184"
     CDS             2027..2974
                     /locus_tag="ACG84X_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9128017.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3104..3844
                     /locus_tag="ACG84X_002185"
     CDS             3104..3844
                     /locus_tag="ACG84X_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128018.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4135..4803)
                     /locus_tag="ACG84X_002186"
     CDS             complement(4135..4803)
                     /locus_tag="ACG84X_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9128019.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            4937..5224
                     /locus_tag="ACG84X_002187"
     CDS             4937..5224
                     /locus_tag="ACG84X_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128020.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            5640..7178
                     /locus_tag="ACG84X_002188"
     CDS             5640..7178
                     /locus_tag="ACG84X_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFP9128021.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7175..8140
                     /locus_tag="ACG84X_002189"
     CDS             7175..8140
                     /locus_tag="ACG84X_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128022.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8127..9449
                     /locus_tag="ACG84X_002190"
     CDS             8127..9449
                     /locus_tag="ACG84X_002190"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFP9128023.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      9512..9616
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9690..10433
                     /locus_tag="ACG84X_002191"
     CDS             9690..10433
                     /locus_tag="ACG84X_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9128024.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            10448..11440
                     /locus_tag="ACG84X_002192"
     CDS             10448..11440
                     /locus_tag="ACG84X_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9128025.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            11452..12189
                     /locus_tag="ACG84X_002193"
     CDS             11452..12189
                     /locus_tag="ACG84X_002193"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128026.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12179..12901
                     /locus_tag="ACG84X_002194"
     CDS             12179..12901
                     /locus_tag="ACG84X_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFP9128027.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(12985..>13404)
                     /locus_tag="ACG84X_002195"
     CDS             complement(12985..>13404)
                     /locus_tag="ACG84X_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFP9128028.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         4416 a         2294 c         2786 g         3908 t
ORIGIN      
        1 aaataaaaac tgtctaacat ttaaaattta atttagatat tagacagttt ttaagtttgt
       61 gagttatttt ccttgtcgtt ttctcacttt tttagtccag aaaccacctg aaatatattt
      121 tggctcataa gaaatgataa aagcacgctc ttcgatttct ttgatcaggc gatacagttc
      181 acgttcgctt tttctaggag aaagtatttc gagaactagc cgctcacctt ccagccccat
      241 tgcagaagtc tgtgtcacac cataaccgtg ttctctcagt atacccggca aacttttatc
      301 ttctgcgcta tttgctggca aaatcgttgt gaccatgatg tatcctaatg ccaatttgtc
      361 ttcaatcaaa attccgacac tgatacctac tgcgtaacct aacgcataga caaataaatt
      421 cagtggatta tctaaacgat ctaaaacaag ggataagccg acgatataaa tcgtgatctc
      481 gaccatactg acaagtggag caatcagtcg atagcctttc attgtcaaca tgaaacgtaa
      541 cgtgttcaga gtgatataag caaaattaat gaggaagatc atccccaaca tttttggatc
      601 aatcatttgt aaaactcctt tcatttatat aacaacaata tcaaaaaaaa tcgtaagtga
      661 agaaaaattg aaactttata catacaaaaa aatgataaaa tgattataat agaattataa
      721 agataggtta ggtgattaaa atgaaaacgg tcaatcgtgt gttttgtgcc agccacgtgc
      781 taagtctcct tctcagtata tacttaggtg tctattcgat tcaacagcca attgaggtag
      841 agaacattgt ttttcagatg tcgctgacag atggtttaat tttaagcgtt tttttctttt
      901 tgatactgtt tattggtaat attttcggta gcgttgccag ttttttgaat ttttctattt
      961 atccactcct ttcgctagca ttaggagtgg tgggactttg ttctctgtgc ttatttcccg
     1021 agccattcag tcctgcattt atattatttg gtacactgaa cctgttccag acaactgttg
     1081 gagcatggtt gctatggcga tcaggaaatt taatgaaaat aggtgagtaa caattgaatc
     1141 caattatatt gaaacgttct gtccatcata ttccagtgtt agaagttgtt ctgaaagaat
     1201 taagagagga acgtattccc gttgtcatct attatcacgg atggcagaca agtaaggagt
     1261 tagttttgac gcaaggaaga aaaattgcgc agcagggcat tcgtgtgatc ctgccagatg
     1321 cgatgaatca tggggagcgc aaacagccgg tttcttctat tccatcctat acattttggg
     1381 atagtatcta cggaaatctg tttgaatttg acacacttat caagcattta gaaaaaagag
     1441 gtcttctaca tgatcagctt gcagttggcg gggtttcgat ggggggaatg acaacatgcg
     1501 ccttgttggc taaacatcct catatagtag cgggcgtgtg tttgatgggt tcccctgcac
     1561 ctttggaata tggaaaagaa atcgtaaggc gcgcatcgga atataattat gtcgtaccaa
     1621 aagactattt tgatttgatt tcatgggtta agagctatga tttgtcattg cagccggaaa
     1681 agttagctgg acgtcctctg ttcttttggc atggacaagc tgacgaaaaa atcccttata
     1741 tacaaacgga acgatttgta gaaaaaaatc ggcataagtc ttacggaaaa gaaattgttt
     1801 ttcgttcctc aaaaacacag cgacatatgg tacaaatacc actaatggaa gaagcttcca
     1861 cttttttagc aaaaaatttg ataaaaaagt ataaataatt gaaacggaaa atcactcatg
     1921 acgatagagg attttccgtt ttttattttg ggctataata aactctgtta ggaaaatttg
     1981 gtataattga tagtaagaat gacaacatgt tagaaaggaa gagagcatgc ccactttagc
     2041 agatgttgca aaacgtgcca atgtttcaaa aatgacggtc tctcgagtca tcaatcatcc
     2101 ggaacaggtg actgacgaat tgaaagagtt agttttctca gcaatggctg aactggatta
     2161 ccgtccaaat attgctgcaa aagcacttgt cacgaatcgg tcgcagatca tcaaattatt
     2221 tatactggaa gaaatcgaca caactgagcc ctattacatg aatttgctga tgggaatcgc
     2281 taaacggatc ggtaaagcgc attattctct ccaattagtt acaaatgatg ccttcgacgt
     2341 cggttcttgt gatggataca tcatcacagg tgtcagaaaa aaagacttcg attggatcga
     2401 ccgtttggaa aaaccagttg tcttgtttgg ggaaaattct gaaggatatg attatgtaga
     2461 cagcgataat gaatatggta cagcaaaagc aacgcaatat gccttagaaa gagattatca
     2521 aacgattatt tatatcggta tcgaagtgga cgagcctttt gaaatttcaa gggaaactgg
     2581 ttatttatct gtgatgaagg aagttgatct tcctagtaaa atcttgcggt ttccaaatca
     2641 ttcgacagaa gtagaaagat atatgacaga aaactgggca gattttacag ataaaacttg
     2701 ttttgtatgt agttcagatc ggctagcact aggagcagta agagggatta taaatgctgg
     2761 aggacacttg cccgaagaat ttggtgtgat tggatttgat ggggtatttt tagaccaaat
     2821 cagttcacct aaattgacaa cgatcaagca agatattata cgtatgggtg aagtatgtgg
     2881 agaaatgttg ttaaaaaaaa tagaagaaaa aggggcgagt caaggttatc gtcgtttttt
     2941 tcctgaacta gttatcagag agacaacgaa ttaagtctta ttactatata tatatttatg
     3001 aaattcatcg ctattttctt aaaataatca gcgcattgct actgaaaaca atgaatctgt
     3061 gctattattg agaaaagttc catttttgag aaggatggtt tgaatgaaag aaatcagacg
     3121 aaaacatttc cgttttcctg cgtacgatga tgagttaggc gtaaaattaa ccaacgacaa
     3181 gaagcgagta ttatttgacg gacaagaaga tcttttgact gaacagaatc agtccccgtt
     3241 tgaacagatg aaagaatttc atttcacgaa cacgaacacc gagaaaatcc gtcgcaagcg
     3301 tcgtgcaaca aatggattga agtcagctcc gcgtaaggaa aatttggaaa agcataaagg
     3361 aaaattaccg gattataccg gccattacca atcagaaatc acatcgacag gacgaaaaaa
     3421 actttttggt gattcctctc gttctgtcag acaaagtgaa acaaggacag agtccaagca
     3481 tactacacga aacgcatctg ttgacacgaa ggtgcgggag cgttcttatt ttgttcctaa
     3541 atatgtaccc gcatcgatta tcccagaccc tagagaaagc aaaatttctg aggatcattt
     3601 aatcgaatcg atgaaaaaaa cggatgactc ttatctgttg ttcgatacag aaccgacgcc
     3661 gtatcaagaa aaaagaaatg gtgagccgtc tgtacgaaca ttcaatcgaa caaaaacgtt
     3721 agaggaaaca aagcagtcag aagaaaaaaa atcgaaaaaa agccatggta tcttagaacg
     3781 ctcattacaa ggattgatcg atgatcaagg aaactctttg ggagaaaata gctattttaa
     3841 ataagtgata tacaaattta tattcggcta cagttggaaa ggaaacgctg cggcgtttcc
     3901 ttattttata ctctatccga aagtttatat cgtatcctca aatttttttg agtttaagcg
     3961 aattttttct cccaataagt aagaaaataa tggcaaaata aaaaaacaaa ctattttcgc
     4021 agatcgtttg caaaaatagt ttattttttt ataaagaaga ttttactgaa taatatcatt
     4081 ttagtttaca taatgatatt tctgtaaatt aaataaagta gtgaaaaata agaatcagtg
     4141 ctctaactgt tcaagaggat caagtggttc aaatgtttct gtagtctgtt ttgcttccaa
     4201 ttggggcaaa acagatccaa tttccagata cttcacttta ttcaatgtat aagatagaat
     4261 agaacagcta agtaatgtat acagaaaatg tgtgagatcc aaataaagca aggagacaac
     4321 taaaatacca aaagtaatca agaaaagact tttgccaatc ttaatatgaa aatatttttc
     4381 aatggcttga taaatgatat ctgttccgcc tgtgcttccg ccgaatcgaa agacgagacc
     4441 gcaaccaatg ccagaaagaa tacctgtcat caaactattg atcagtagac tatctacagc
     4501 aaaatgtata tgaaggctct cccataaatg taaaaagaaa actagcgcaa atgttccgac
     4561 gatcgtccgg agaaaagcgt gttttccaaa aagaaacaat gagataagca ataaaggtaa
     4621 attaaaaagc agtgaagtga cagaaggagc gaatccaaaa agattatgca aaagcaaagc
     4681 aataccagta accccaccat ctgccagctt agatggaata ttgattcctg tcacagctaa
     4741 tccgtagatt cctgcgccta aaatgattcc gcacaattct gtaaataaat ttaatttttt
     4801 catttctagc ctcttttctt ttgaaaattt tcagcaactt ctttattata ctgacttata
     4861 ctcttacttc aagaggaaaa tgaaaaaaaa ttatttttgg ctgtttcttt ttatttatca
     4921 aataaggagt ggaaaaatgc gagcagcaga cttattgaca attcttacaa aatcacccaa
     4981 aaaaacagag tatcaaggag tttttttggc tcaagaacaa aaactggtgc ctgtgacaat
     5041 ggtccagata aataaagcaa atcaatttat ctttttattt gaacacggca aagcaccact
     5101 tgctatgaaa gacatctttc tttttttgat gaagaaccgt gagaaagctg tttattatca
     5161 gtcaaaagaa gaactcattc ctctttatgg agtgaaagag atagaaaata aagtggtgat
     5221 ataagtaaaa ataagaaaac aagacgttta tgatgtcaaa acaaccattt tttacatttt
     5281 tggcaaaaaa gtgtcatgat acagtataat attcgttgaa caggccaata aaggtgttct
     5341 cccccacgag atttctactt tattggctgt ttctttttat taaaataaaa gttgtgtgtg
     5401 taaaaaagat atagctgatt ccaagtgaca atttcgtata gatttttatg gtattcgtag
     5461 tgaaaaaacg agaaccaaaa agttgatccg actttgttgc ttggattctt tttttgtcag
     5521 catatttaga ggtatttttt tctttttttt gttcgtgctg taaggttaag gcaagacaag
     5581 ttagttggga aaaaggaaag aaatgtttat acttaaagaa taacagaaag gaaggtcgca
     5641 tgaataattt tatacaaaca ttaagtgaaa gaaaaggcga gttgctggaa gctgcatttc
     5701 aacatctgtc catttctctc atttctttgc tgattgcagc actgattgct attcctttag
     5761 cgatttgggc agccaatcat aaaaaaatgg cagaagtctt attgcagatc acgggtgtgc
     5821 tccaaacgat tccttcactt gccttattag gtttacttat cccatttgta gggatcggaa
     5881 ctgttccagc attgattgca cttgttattt acgctttgct tccgattttc caaaacacgt
     5941 atattggtct agctgaaatt gacccgtcta ttgaagaagc agcggtagca tttggtatgt
     6001 ccagaatgag acgcttgctg aaagtagagc ttcccatcgc attacctgtc attatctcag
     6061 gtatccgaac tgccttagtt ttaatcatcg gtacggctac tttggcagca ttgatcggag
     6121 caggtggatt agggacattt attttgttag gtattgaccg aaatacacct gttttgacat
     6181 tgattggtgc gatcagttct gccttgcttg caattatatt cagcggactg attcgctggt
     6241 tgcagcataa gaaacctcga tattccatca ttactttagc agcagtggtg tgtttatttg
     6301 gcggcgtttc tttatatcag tctgccttgt ttaaaaatga aaccatcacg attgctggaa
     6361 aattaggagc ggaacctgaa atcctgatcc aaatgtataa agaattgatt gaagacaaca
     6421 caaaaacaga agttgaatta aaaccgaatt ttggcaagac gagttttttg ttcaatgcac
     6481 tggatcaagg tcaaatcgat atctatcctg agttcacagg tactgtccta gaaagcttgg
     6541 tgaaggtacc tgaagcaatg aaaagtgctg atttgacaaa agaaaaaaca tatgacgaag
     6601 cagaagaatt attgaataag caattcgata tgacattatt aaaaccaatg gcttaccaaa
     6661 atacgtatgc cttggcagtc aagagatctt ttgcgaacga acatcaactt aaaaagattt
     6721 ccgatttggc agctatctct gatcagatca aagcgggatt cacactggaa tttattgatc
     6781 gttcagatgg atataaagga atccaagaag catatggctt gaatttttca agtgtacaaa
     6841 gcatggagcc aagtttgcgt taccaagcaa tcaataatgg agatgtcaat attgtggatg
     6901 cctattccac agatagccag ctcaaggagt acgatctagt gactctagaa gatgatcgag
     6961 ggttattccc agcttatcaa ggcgcaccgc tgatgaaaaa agattttgct aaagaacatc
     7021 ctgaaatcgt taaagcactg aataaattaa gcggaaaaat aacagaggat caaatgattg
     7081 atatgaatta ccaagtcaat gtcgaaaaga aaaagccgac agaagtagca cgaatcttcc
     7141 tgaaaaatga aggattagta aaggaggaag atcagtgact aaattaatcg agttcaaaca
     7201 tgtgcaaaaa aagtatgatg gaaagtatgt catcgatgac ctaaatctgg caatcaaaaa
     7261 aggagaaatc tttgttttgg ttggtccttc cggtagtgga aaaacaacta ctttgaaaat
     7321 gatcaatgga ttatctaaac catcagcagg agacatctac ttcaaaggaa aatcgttaaa
     7381 tgaatataat ctgcagaaaa tgcggtggaa tatgggatat gtgctgcagc aaatcgcttt
     7441 gttcccgacc atgacagtca agcaaaatat tgaagtcatc cctgaaatgt taggttggga
     7501 aaagcagaaa agagcagacc gtgtagatga acttcttcaa aaagttggct tatctcctga
     7561 tatttatcga gatcgtatgc ctagagagtt gtctggagga gaacagcaac ggatcgggat
     7621 catccgagct attgctgcaa gcccagatgt gattttgatg gacgagccat ttagcgcatt
     7681 agatccgatt tcaagaaact cattacaaga attggttttg tccttacacg aagaattggg
     7741 cacgaccatc gttttcgtta cgcacaatat ggaagaagca atcaagctag gtgatcgtat
     7801 tgcatttatg aaggatggag aaattatcca atgtgacaca ccagagcagt tattgatgaa
     7861 tcctaaaaac gactacgttc ggcatttctt tgatgaaccg aaacagacga aagagtggcg
     7921 agtagaagat ttagtcgtca atggatattt cttaaatgaa ataccagaaa atgctcgtca
     7981 acaagtttgc tttgatacgc ctatgaaaga agtatattcg cttctttcgg tgtatccaag
     8041 cattgtgata gtagaaaagc aaagaagtat tgggtcgctg acaagtaaag aaatctttgc
     8101 ttttttaagt cgagaggagg aaggaaatga aaacatatga tgcaatcatc atcggttcag
     8161 gtgtgagcgg cttaagtgct gcttatggat tgaaagaagc aggtaaaaca gtactagtgg
     8221 tcgaagaaga tctatggggc gggacttgtc ctaaccgtgg atgtgatcct aaaaaagtct
     8281 tgttaagtgc agtagaggca cgtaatcggg taaaacaatt gagtggaaaa ggttttaacg
     8341 agatcccaac tgccaactgg gaagaacttc aaaaattcaa acgaacattt acggatccag
     8401 tcccagaaag ccgaaaaaaa caattagcag aagctgaaat cgatcatctt tcaggaaccg
     8461 ctcgtttttt ggatgattca tctattgaag tcaacgaaga agtcttccat gcggattact
     8521 tagttttggc aaccgggcaa agacctacga tcttaccagt ggagggaaag gaatacttga
     8581 aaactagtgc agacttttta tcattgcctg tactgcctaa agaaatcatt tttatcggtg
     8641 gtggttatat tgcttttgag ctagctacga ttgccaatgc tgcagggagc aaagtaacca
     8701 ttgtccatca taatcaacgg ccattaaaag aatttgaggc gtctttggta gaggaagccg
     8761 tccatcaaat ggaagcatct ggcattcagt ttgcttttgg tgttgaaacc caaaagatca
     8821 tttcagaagg tactcgctat cgtttagtcg gaaaagagac ggaattagta gcagatatga
     8881 ttttttgtgc gactgggaga cagccgaata cagaatcttt agcacttgag caagcgaata
     8941 tcgtctttga taaacacgga attgcagtca atgattatct gcaaacgagc aatccaaaaa
     9001 tttttgcgtg tggagatatt gtttcaagga aaaccccaaa attgacacca gtcgccactt
     9061 ttgaaggaaa ttatgtagct aagcggataa cggatgcaac aagcgaacct atcaaatatc
     9121 cgattatacc tacgatcgtc tacgccagtc ctaaacttgc tgaagtagga gttacaaaaa
     9181 gtcacgcctc ttcgtcagat caagtggtag agatggatct taccagttgg ttcacctatc
     9241 atcgtgtcaa tgaaccagtt gctaaggctg aattgacctt tgaccagcaa aattatttga
     9301 ttggtgctgc agtgattagc gagcaagcag acgaattgat cgatgatttg acactcgtca
     9361 tcaatcaaaa attgactaaa aaagagttgg atagctatat catggggtat ccgacattgg
     9421 caagtgatct ctcctattta ttgaaataat cagcatgata actaaagcgc ttgttgcttt
     9481 ttccttcttg tgctacactt taaaaaatga atacctgttt ctggggatgt cgtagacgac
     9541 atgagagtaa gttgtgaact tagacccatt gaacctgtca gttaatactg gtgaagggag
     9601 aaacatagca gacgcttgaa gcgggttact atgtcgtgcc catttcaagc gttttttgtt
     9661 attcatatta gaagaaagga ggtaacaaaa tgaagaaaaa tctttatcca gcagtcagta
     9721 tggcattcat tttaattatt tggcagattg ttgtcatagt ttggaaaata cctgccttta
     9781 ttttacccgg acctgctgct gtattttctg cattagcggc agatgcacaa gtattacttt
     9841 cccattctgt cacgacatta aatgaagcag tgcttggttt ggtaatagct agcgttcttt
     9901 cttttattac tgccttggca atggattatt ggaagttttt agaaatgtct ttttatccgt
     9961 tactagtgat ttcacaaatg ttgccaatca tggtgttagg gccattactt accctatggt
    10021 ttggtttcgg tatgcttcca aaagtgatcc ttgttgtctt gataagctat tttccgatcg
    10081 tagtttcttt ttcggataca ttgaggaaag tatcaaaaga gcaaatcatc tttttgaaaa
    10141 cgatgggggc agatacaggg aagatttatc gaatatataa aataccagcg ggtttatccg
    10201 gcttcttttc cggtttaaaa gtggctgcta cttattgtgt cagcggagca gtcgttggag
    10261 aatggctaag cgctcaagca ggcttagggt attacatgat acgcgtaaaa aacagctacc
    10321 agatcgataa agtttttgct gcgatcattt gtgtcattct attgagttta ttgctgaatg
    10381 gcgcttgttc attattgaaa aaagggtatt atcgtatgct ttatattttt taagagaagg
    10441 ggatcaaatg aaaaaattat ggcttttatt accgctactg ttgcttttat ccgcttgtgg
    10501 cactgcaaaa gaaacaagta gcaaacaaga aataaaggat ttgaaaaaag tgacacttgt
    10561 tttggattat gtaccgaata ctaatcatac tggcatctac ctagcaaaag aaaaaggcta
    10621 ttataaagag gctggtttaa atgtccaaat catcgaacca ggagataatt cgacaagtat
    10681 tggtctagta ggtgcggaca aagcacaatt tggtgtaagt tatcaagaag atgtcactta
    10741 tgctcacgca gatggacaga atataccagt caaagcaatt gctacagtga tcaaacataa
    10801 tacttctgga ttcgccaccc tatcagacag taacatccat tcaccaaaag attttgaagg
    10861 aaaaacatat gcaggttggc aaagtccaag tgaagaagct gtcttaaaag ctgtgatgga
    10921 aaaagacggc ggggactttt caaaactgac aatggtagga agcaatggag aagggccaga
    10981 aagcttagga aaatcctcag atatccaatg gtactttgaa ggttgggata tgatcaaagc
    11041 aaaagaagcg ggtattgaac taaactatat cccattgaaa gaattagatg aacggttaga
    11101 ttactatact ccggtaatta ttacgaatga tcaactgatc aaaagtgatc cagaattggt
    11161 acagtctttt atggatgcca cgaaaaaagg ctatcaggaa gctattaagg atccaaatga
    11221 cagtgctaaa ctgttgcaaa aatatgcaaa agaaaatgat cggacgtttt tagaagaatc
    11281 acaagcattc ttgtcaaaaa attatacgga tgatcctgag aattggggat tgatggaaga
    11341 aaaagtttgg cgcaattata cagcttttat gcaggaaaac ggattgatca agcaagatgt
    11401 accttcgcaa gaactattca ctaatcagtt tataaaatag gagtgataga tatgtcaatc
    11461 caaatcagcc acttgaatgt agtcattgaa aacctgaaaa tattagaaga catccatttc
    11521 actatcccta aagatacctt tacatcgatt gtcgcgccaa gcggagccgg taagtcaaca
    11581 ttgctgaaaa ctttaacagg agtccagcct atgacttctg gaacgatcaa agtagacgat
    11641 caaaaagtaa ctggtctcca tacagcattt agttatatgc cgcaagaaga tatgttactt
    11701 ccttggctga gcgtctatca aaacgttacg ttatatcaaa aaatcaatca tctaacaatc
    11761 aatgaagaac aagtaaggga ttatctggat atctttgggt taaacggcta tgaacatttt
    11821 ttgccggaac aattatctgg cgggatgaag cagcgaacgg ccttgttacg aacaatcatg
    11881 aatccttctt cttacttgct tcttgatgaa ccatttggag cgttagatgc tatgaccaga
    11941 gggcagatgc aagactggat gttgaagctg cctaaaaaag caaagcggac tactttactt
    12001 gtgacgcatg atatcgaaga agcaatttat ttatcagaca ggattcttgt gctttccgcc
    12061 cgtccggcac atgtgattgc tgagattcaa gtgcctgaaa aacgacggtc acgtgaatgg
    12121 ctactgcagc aatcagagtt gaagcaaacg atttatcagt tattggcagg tgaattagat
    12181 gttaagtgat gctcattgtc atttagatgg gagtcagagt ttagcactcc ttcagcagga
    12241 acacacgatt ttgacgatca tcaattgtga ttcgccagaa gaatggaagg aaaacagaca
    12301 gcttgcagca agtaagactc aagccttaag ttacggtatc catccttgga aagcagatag
    12361 ctatacgttt gaacaagttg agcctttttt gaaaaaagca aggatcatcg gtgaaatagg
    12421 gttagataat atttggacga atgtaccgat gactacacaa aaaaaagtat ttgagcgaca
    12481 gcttgctttt gcagccataa atgagaaacc tgttgtactg cacacaaaag gatgcgaaaa
    12541 agagatctta aattatatcc aagcttaccc taatcactat ttgatccatt ggtattcttc
    12601 tttggactat caacaagact atattgattt aggctgttat ttcagcattg gtcttgattt
    12661 gaaaaagaat ccagcagtct ggcaactagc taaagcagtc ccaatcgacc acttacttat
    12721 tgaaacggat ggactacatg cagcagagtg ggctttaggg gggatttttt cagaaaaaga
    12781 ttatgtctca ctgcttgaag aacagttaaa gacaatcgct gagatcaaag agctatcagt
    12841 tgaagaagtt aaaaaaaata cttatcaaaa cttggaacgt ttcattagat taggtaaata
    12901 aaaaagagat gtgacacaac tagtgtcgca cctctttttg gctttctttg tataaaagta
    12961 aactgtttga ttaataaatg aatcttagta ccaaccgttt gcttcccaga atgctttcgc
    13021 cgcttcccaa gaaccataac gtgaagtaac atattgttct gctactcttt cttggtttgc
    13081 agcagagtag tcaccattta agtaagaaga atctaattgg taacgtccga tgtaacgtcc
    13141 gttcgttgct gtgtaagaac cgcttgattc tttttgtgcg atccattctt ttgcagagct
    13201 tgtgcttgct ggagtagcag cagtttctgt tacagcagga gcaggttgtg tttcagcaac
    13261 aggcgctgct tgtttttccg tttgaaccgt ttcttgtaca acaggttgtt cagcttggac
    13321 tggtgcttct tgaacggctg cttgaggttc agcagctgct tgtgcagagc cttctgttgg
    13381 gattgttaat tgttgtcctg agta
//
LOCUS       DAZKCH010000073        13256 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000073 DAZKCH010000000
VERSION     DAZKCH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.074"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            223..1962
                     /gene="yfcC"
                     /locus_tag="ACG84X_002196"
     CDS             223..1962
                     /gene="yfcC"
                     /locus_tag="ACG84X_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFP9128029.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2119..3303
                     /gene="iadA"
                     /locus_tag="ACG84X_002197"
     CDS             2119..3303
                     /gene="iadA"
                     /locus_tag="ACG84X_002197"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFP9128030.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3414..3617
                     /locus_tag="ACG84X_002198"
     CDS             3414..3617
                     /locus_tag="ACG84X_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFP9128031.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3718..4380)
                     /locus_tag="ACG84X_002199"
     CDS             complement(3718..4380)
                     /locus_tag="ACG84X_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128032.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4393..5895)
                     /locus_tag="ACG84X_002200"
     CDS             complement(4393..5895)
                     /locus_tag="ACG84X_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9128033.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESRETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6443..8122
                     /locus_tag="ACG84X_002201"
     CDS             6443..8122
                     /locus_tag="ACG84X_002201"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFP9128034.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8249..8728
                     /locus_tag="ACG84X_002202"
     CDS             8249..8728
                     /locus_tag="ACG84X_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFP9128035.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8947..9627
                     /locus_tag="ACG84X_002203"
     CDS             8947..9627
                     /locus_tag="ACG84X_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFP9128036.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9635..10966
                     /locus_tag="ACG84X_002204"
     CDS             9635..10966
                     /locus_tag="ACG84X_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFP9128037.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10981..11943
                     /locus_tag="ACG84X_002205"
     CDS             10981..11943
                     /locus_tag="ACG84X_002205"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFP9128038.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            12054..12392
                     /locus_tag="ACG84X_002206"
     CDS             12054..12392
                     /locus_tag="ACG84X_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFP9128039.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12471..13178
                     /locus_tag="ACG84X_002207"
     CDS             12471..13178
                     /locus_tag="ACG84X_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFP9128040.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4248 a         2326 c         2896 g         3786 t
ORIGIN      
        1 taaaaataaa aaaagaattt taaggaaaaa cagagaaata aaatacttaa tataaatgga
       61 aagagaaaaa aataatcata cataggagaa aaaaaacaaa atagaaaaaa gtgattttct
      121 aataaattat tcatgtggaa atgtcatttt tactgtataa ttcatttgat tatccatttt
      181 ttattcatca aaattactga aaaaagaaag gaagaaataa atttgaagaa aacaaattct
      241 tcaggaaaac cgaaacgcga cttcactaaa ttatcgacac cccatacgta tgtcattatt
      301 tttggtgtag tcatctttgc atggatactg acttttgtcg ttccagcagg aaagttcagc
      361 acgcaagata ttgaatacaa agatgcaaat ggcgaaacaa gtactcgtac tgttttacgt
      421 caagattcct tccgttatgc ttacgagctg gataagtcgt atgtgtttga tcaattagaa
      481 gaactgcaag atcatccagc agaacgtgaa aaactggatg ttccggaaaa aggattggaa
      541 aaagtcattg ctgacggaga aaaaaatctt acgcaggaaa aactagatga aatctccttg
      601 acagatgatg tgctttacga tcagtacggc gaaaatatct atgatacttc taaaaaattg
      661 cataaaacag ccaaaatatg gggaacagat gattttggcg gctttggttt cttaaatttt
      721 gtttttgaag gactagtatc tggagataag tatggatctg ctgtagggat cgctgcattg
      781 atccttgttg ttggaggtgc ttttggtatt attatgcgta ccggagcgat cgacgcaggt
      841 atctatgcgt ttatcagtaa aactaaggga ctggagcgtt tagctttacc gctattattc
      901 tttgcttttt cattcggtgg cgctacattc gggatggcag aagaggtaat tccattctca
      961 atggtgatgg ttccatttgt cattgcgtta ggatatgact cgatcgtagc agtaaccgtg
     1021 acttatgtcg catctcaagt cggaaatgcg acctcttgga tgagcccgtt tagcgtagcg
     1081 gtggctcaag ggattgctgg aatccccgtg ttgtctggtg cgacattccg attgattatg
     1141 tgggtagttg ttactgcatt agccgctggt tatatgatga tatatgcaga aaaaatccgt
     1201 aaaaaaccag aaagttcgtt gacttacaaa tcagatgatt atttccgttc tcatatcaaa
     1261 aagacatctg atgaaaataa aaaattcatg cttgggcata aattgatctt attagagatg
     1321 ttagttgtcc ttgtctggat cgtttggggc gtgactcaaa aaggctatta cattccagaa
     1381 atcgcttctc aattctttgt gatgggatta gttgctggaa tcattgctgt tcttttcaaa
     1441 ttagatggaa tgaaagtcaa tgacatcgct tcttctttcc aatctggtgc agctgattta
     1501 gctggtacag caatcgtagt aggtatggcc aaagggattc ttcttgtctt gggaggatct
     1561 gatgcatctg ttccttcagc tttgaatacg attttgcatg ggatcgggac ggcgttgacc
     1621 ggtgttccag ctgtcattgg tgcttgggcg atgtacatct tccaaagttt gttcaacttg
     1681 gttgttacat caaattcagg acaagcagct ttgactatgc caatcatggc tccactggca
     1741 gatttagtag gtgtatccag acaagtagca gttcttgctt atcagcttgg ttcaggtttt
     1801 atggacgctt ttacacccgt atcagccagc ttgattggtg tgctaggtgt tgcacggatc
     1861 gaatgggcaa aatgggcaag attccaaatc aagatgcaag gattcctgtt tgttttagga
     1921 actattttca tcatgattgc cattgcaata ggtctgcagt agtactggag acctgtaaat
     1981 aaaaaagtaa tccaaacagt agataaggac tccaagaacc gtcattttac ggtaaaatca
     2041 aaggagtaaa gatcctatcg tttggattat tttttaagat cctatcatca gttatactta
     2101 aagaaagagg aaaaatgtat gaaaatcatt cgacaaattg aagtgtttgc accagattac
     2161 ttaggaaaaa tggatgtact gattgccggt gggaagattt tggctgtaga agaacagcta
     2221 gaaggcggct acgaaggagt ggaagtagaa gaactttcag gtgagggaaa agtactaacc
     2281 ccgggtttca ttgactgtca tttccatatt ttaggtggag gaggagaagg cggttatcaa
     2341 aatcgaacgc cagaagtcac attgagccaa ttgactacag ctggtgtaac gacagttgtc
     2401 ggttgtttgg gaacagacgg agaaggtaga gatatgactg cgttgatcag caaagcgaaa
     2461 ggtctggaag cagaaggaat ctccacttat gtatacgaag gttcgtaccg attgccggta
     2521 aaaacagtaa cagattctat catcaaagac tttttgacaa ttgataaaat tatcggaatc
     2581 ggagaaatcg cagtatccga tcaccgttct tctcagccaa gttttgaaga gttcgctcgt
     2641 gcagtagcag atgctcgtgt aggaggcatg ttatccggaa aagctgggat catcaatgtc
     2701 cacttaggcg gaggaaaaag aaagctagag ctattgacac gaatcgtaga agaaacagaa
     2761 attccgatca cacaattttt gcctactcat gcaaatcgca caccagaatt atttgaagct
     2821 tgcgtggcat ttgccaaacg tggtggcacg attgacttca ctgctagcga agatcctgat
     2881 ttttgggaga agacagatgg tgaagttcgc ttcagcaaag cactgaaacg attgatcgag
     2941 gaagatgttt ctttagataa tttcacgatg acctcagatg gacaaggaag cttgccttat
     3001 tttgatgaaa acaatcattt cctagggtta ggagtaggaa gtgccaaggc attgctagta
     3061 gggatcaaag aagctgtgca aaaagaaagt atccctttgg aaatcgcctt acgagctata
     3121 accagtaatc cagcacgtat attgaaattg gataaaaaag gaaaaatcga aattggtgct
     3181 gatgcagatc tgtgtatctt ggataaagaa acgcttgata ttgatacagt tatcgctaaa
     3241 ggagaaataa tggtccaaga aaaagaagtc aaagtatggg ggactttcga aaaaagtttt
     3301 taatcaacag ctctaactat cttttttaga aaacgagcgt tctgtttgtc tgtatctgtt
     3361 gttgatgtta ccctgaaggt agatcaataa acaaactaag aggaggaagc acaatggcag
     3421 atttaaaagg acgttctaaa gatatgaaag ataaagtagt cggtgaagga aaagaagcat
     3481 acggcaaagc aacagacgac aagagcaaag aaacagaagg gaaagcacaa tcactaggtg
     3541 ctgacatcaa agaaaaagct cgaaatttag gcgacgaagt caaagacaag ttttctcgaa
     3601 aagacgaaaa aaaataaaaa ccacttatta ctaattgaat caagcaaata aaaaatccga
     3661 accatatctg cgagacagat atggttcgga ttttttattt gatcattatc ctgtttttta
     3721 aacttcgatt ttttgaaatt ttttattttt tagttcaaag acttcatcac agctttttgc
     3781 tacttcaatc tcatgagtca cgatgataat acagcgattt tgttcatggg cgatttcttg
     3841 gaaaagtttg acgatatctt gtgaagttgt ttcatctaga tttccagtag gctcatccgc
     3901 tacgattagt tgatgttcac agcagatagc acgaacgata gcgactcgct gctgctgacc
     3961 tcccgaaagt ttggtcacct gtttttttgc taatatttca tcaattccta cacgagccag
     4021 tcgatctaaa gcaacttgtc gataattctc ttgcttggtc ttagtgattt ccattgctgc
     4081 tatgacgttg tctagagccg ataaataagg aagcaagttg taagcttgga aaataatcga
     4141 gacatcattt ttacgataac ttcttaaccc gattttgttc agtgaacgat cttgatagta
     4201 tacctttcct tcttttggtg catctagtcc agaaataagc gaaagaaaag tcgtttttcc
     4261 agaaccactt gctcctaaaa tagcgtacat ttttccagct tcgaaattca gttctacatc
     4321 tttataaagc gcatcttgcg gatcttgata ccaaaatccc aattgttctg tccgtaacat
     4381 caaattcctc ctttagttta ataggatttt tcttgggttt aatcttaata tccctataga
     4441 agctaaaaag acagaaaaca gactgattcc aaatgctact ccggctaata gtcccaattg
     4501 tgcaggtttg acattgattt ccaattcgct gacttgatca gaaacagcaa atggattatt
     4561 cgtggttcct tgttgaccat cgcgttgacc gccttgttct tgtctgttac ctggcatttg
     4621 tccaccgcca ggagcttgct ggttttgtgt cgtggtttct gtctgttggt caagtagctg
     4681 ctgtcccacg gcattcgcga cgacgtttcc gctaagcgaa gcaactccta atgcaagaat
     4741 catacaaata gccacttcgg taaacaattg gagaatgatt ttacttctgg attctcctaa
     4801 agatagcaag acgcctaact catgccgacg ctcccgaatg gtaatcataa tgatcagagt
     4861 aagtatgata ataccggcta cagccactag taaaacaaca tttttagaaa aacttgccac
     4921 gttgtttaaa ggttccaaca ttgactgata catggaatca tttgattgta agctaaatgt
     4981 atctgtgtcg atcagcttct cagcttcttt gagaaactca tccattttat ctggatcaga
     5041 tagagtgtaa atagcagaat ctatcgtgtt atcgtcagat gtcccattta gttcatttgc
     5101 aaaagtgtaa gaagtgtaaa gtgtattcga cggattcatg aagttgaatt tcatacccat
     5161 actgccgctt gtttctctgg attcataaat tcctttgatc gtcatttcat aagtggtatc
     5221 ttcatcttca gtactcgtga ttgtgaaagt atctccgact gccaggtcat ttgtttctgc
     5281 tagagtagaa tcaatgacta cattgtttgt gcctttgtcg ctgtcatcta ttccttcacc
     5341 atccgtgatt tttgctgttc catcagaaaa attactattt tgtgcagttg ctgacacacc
     5401 actgatttga aagtctgctt gagtcatttg cggattcccg cccattcctc cagcaggttc
     5461 accgcctgca tcagtagttt ctgaactgtc ttcacttgaa tcagaactag tgatggcagt
     5521 tattccatct tttgccatag ctgaggcgga actttcaaag gaataactct ttacattatc
     5581 taattcagct attttttccg cgtccgttaa ggaaactggt gtaagagaaa aactgcctgg
     5641 atctggacgt tcttcagtgg tagaaccgct tgaagaagtt tgttcctgtt ttttaaatga
     5701 agcttctcga ttggcactta aagtcactgt tgctccaact tctttttgtg cttgattcgc
     5761 tgcttcttct gcagcgcttc gaatcgtgag gccagctagc acaaaaataa gaatggctgt
     5821 gaacacggca aacaataaca atgaacgtcc ccattttact tttgtacttt tccatgcacg
     5881 tttcataaaa ttcatatttt gcatccctcc tagtagatgc atttgataat agacaaccta
     5941 tcttaaagct agcttaaatc ttatgctgtt tgcacaccat caacatgagg ttctgtatat
     6001 ataaaaagtc actatagtta ttgcaaaaaa tgtggtaaaa tgaaaaaagt atgtttcaaa
     6061 ccgacgaaga agaaatgaaa gaggaatagc aaaagaaatc ctagatgcta cagagggatt
     6121 tttacgtgca tagttgttct aacaattgct gatactagcg atttagttta tttgttgtat
     6181 aataatgggg aacagctgaa tacttatata agtattctgg ctatagcgtt tcgcaaaaga
     6241 tccattttgt taatgaagta tatccaaaat aaaatgccca tccaactgtc agaacgcgga
     6301 tgtgctggta attttcctgc tgattctcca taagttgaga aatagtgatt ttgcatatgc
     6361 ttcattggaa tggctcatat atttagataa agaagaaaat cgacatcttt aaacttggat
     6421 gtcataagaa gaggtgaagt ttgtgagtac cattaaaatt atcccattag gcggcgttcg
     6481 tgaaaatgga aaaaacatgt atgtcgcaga agtgggcgag gatattttta ttttagattg
     6541 tgggctaaaa tatcctgaaa atgagttgtt ggggatcgac gtcgtaatcc ctgattttac
     6601 gtatttagaa gaaaacattg atcgtgtagc tggtgtcttt ttaacacatg gacatgcaga
     6661 tgcgatcggg gcacttcctt acttgttgtc aaaaatttct gtaccagtat tcgggacaga
     6721 gttgacgatc gagttagcaa aattgaatgt cagtcgtaat gaagcagcca aaggatttaa
     6781 ggatttccat gtggtagatg agcatacaga aatagacttt ggtgaaacag tagtgagctt
     6841 tttccgtacc actcatacga taccagattc agtggggatc aatctgaaaa caaaagaagg
     6901 tagtatcgtt tatacgggag attttaaatt tgaccaaacg gctatcccaa tgtatcaaac
     6961 agattatgca cgattggcgg aaatcggcaa agaaggagtc ttagccttac taagtgaatc
     7021 ggcaaatgca gaaaatcctc agcctgtagc ttctgaagcc caaatagcag atgaagtatt
     7081 tgatacgatc aaatattggg aagggcgtat catcgtcgct tgtgtagcaa gtaatttgca
     7141 acgagtgcaa caagtattgg atgcagcaga aaaagcacaa cgaaaagttg tcttgactgg
     7201 tcaagatttc gaacgaatta ttcgcacagc gatgcgttta gaaaaacttc aattaccaag
     7261 tgaagatctg cttgttacgt tgaaagacat gaaaaactat gatccagaag aactgatcat
     7321 tttagaaact ggccgaatgg gtgaacccat caagtctctg caaaaaatgg caaacggtac
     7381 acaccgtaat gtcaagattg aagaaggaga tttggtttat atcactacta cgccaagcat
     7441 cgcgatggaa accatcgtgg cgaaaacgga agatatcatt tatcgagctg gtggaacagt
     7501 gaagttgatc tctgagaata tgcgcgtttc tggccatgcc aatcctaatg acttgcaatt
     7561 aatgatcaat ttgatgaaac caacatattt tgtgccagtt caaggagagt atcgtgaatt
     7621 agctgctcat gcagatttgg ctcatgcagt agggatgcca tacaaaaata tctatattac
     7681 tggacgcgga gacgtgctgg aatataagaa caagcgtatg agtgttgcag gaactacaag
     7741 tgcagaaaat gtaatgattg atggattagg cataggtgat atcggaaaca ttgttttacg
     7801 tgatcgaaaa atcttgtcag aagacgggat tttcgtagcg gttgtcacta tcagtcggcg
     7861 agaaaagaaa atcatttcaa aacctcaaat tacttcacgg ggattcgttt acgtaaaagc
     7921 tagccgtgat ctgatgaaag aaagcagcaa tatgattgaa acaatcgttg agaaacattt
     7981 agaaagcaat gattttgagt ggagcaaatt aaagcaagac atccgagatc aattaggccg
     8041 ttacttattt gaacaaacaa aacgccgccc agtgatcttg ccagtcatta tggaagctac
     8101 tcaacgtcga aataaaaaat aaacaaaaag agtaagatga acctctctat agagtgctcg
     8161 tcttgctctt tttttgcgaa aaacaaataa tttttgaata cagcatccct cgctttataa
     8221 taaacgatag aataaaggga gtgaatcaat gatgagtcaa acaaaagtcg aacgttattt
     8281 agaagaacaa aagatcagct atcaaccact tgattttagt catgtggtag aagaatcttt
     8341 cacagaagaa ctacaaaaaa gagggattga tccagctttg atatgtaaaa ctctcgtagt
     8401 gaaaggaaac aaaactgggg tgatcatcgc attgattcct ttgaacgatc acttagatta
     8461 caaaaaaacg agacaagtga cgaaagatcg taaagttggt tttcctggaa tggattttgt
     8521 attaatgcat acaggatatc cccacggagc aaacacccct attggaataa aactcgcaca
     8581 tcctgattat tgttttttag cagacagttc tttaaaagaa aaagaagaag taattgtgtc
     8641 aagcggtgaa atcgggagaa gccttcggat aaaagtagcc gatttagaaa agatcgtcca
     8701 tcctatttac gctgatttaa ttagttaagg gacgagaaga gaagctaagc agagcagaga
     8761 cctcaaactt gagattatat ctgcttggta cttggtgcat cctgtattat ctgttacaat
     8821 tgctttgtac atactgtact atcaatccaa tgaaaatata tttagcagct atattttttc
     8881 attgatgtgc aagtgatgaa atcgttttta ataaaaaaga tacagagaaa acgcgaggtg
     8941 taaaatatga aaattacgta tcatggacat tcctgtttaa caattgaaat ggaaaatggc
     9001 caacgcgtga tgattgaccc gtttattaca ggaaatccat tgacagactt aactgcagaa
     9061 gaagtaaaga cagattggtt gctgattact catggtcata gtgaccacat aggagatatg
     9121 attcctattg caaaagaaaa tcaagccaca attatcagta ttgttgagat tgctgattat
     9181 gcgaacagca gaggagtaga ttcattcggt atgaatatcg gtggaaaaca tgcgtttcca
     9241 ttcggcgtgg taaaattcgt acatgcacag catagttcaa gctatgaagt agacggtatc
     9301 gttcagtata tgggcgagcc tagcggaatt attattcaag cagaaggaaa aacgatttat
     9361 catgcagggg atactgctta tttcagtgat ctaggattgc ttgcagaaga attcgatatt
     9421 gatgtcgctt tcttgccgat tggcgataac tatacgatgg ggccagaaga tgcagcaaag
     9481 gctgcgcaaa caattcgtgc caagaaagta gttccaatcc attacaatac tttccctgtc
     9541 attgaacaag atcccgaatc ttttgtagag ttactggaag atagtgaagg aaaaataatg
     9601 agcgtctcgg aaacgctgga agtgtaggca gaaaatggcg acaaaacatg atttgatttt
     9661 agaatatatt gaaagtttac ctgttggcaa tcgaatttct gtaagaagca tcgcaaaaga
     9721 attgaatgtc agtgaaggaa cagcgtaccg tgcaatcaaa gatgcagaaa atgtcggact
     9781 agtttcaaca attcaacgag tagggaccat ccgtatcgaa cgcaaattaa aaaaacatat
     9841 tgaacgtttg acatttggcg aggtcgtcag gatcattgaa ggggacgttt taggcggggc
     9901 ggcaggatta gacaaggtct tgaataaatt cgtcatcggc gcgatgacta aacatgccat
     9961 ggaacgctat attacgccag gatcactaat gatcgtcggc aaccgggcgg aagtccaaaa
    10021 attagcattg gaagatggcg ccgcagtatt gatcacagga ggattcaata cgactgctga
    10081 gattgcaaag ctagctgatg atcttgaaat gccgatctta cgcacctctt atgatacatt
    10141 tacagtcgca accatgatca accgagcgtt aagcgaccaa ttgatcaaaa aagatatcat
    10201 gcttgtcagt gatatctata tgccagctga aaagactcat tatttgcagc agacagatac
    10261 gatttctgat tatcagcgtt tgtcagaaga aacgcagcat tcgcgttttc cagtcgtcaa
    10321 ccgccatcat cgtttgatgg ggattgttac ggcaaaagat gttttaggga aatcgccaaa
    10381 ccagatcatc gatcgggtga tgacgaaaga accaatcagt gtaaagaaaa caatgagtat
    10441 tgcctctgtt agccatcaaa tgatctggga tgggctagaa gtcatgccgg tcgtttccga
    10501 tgacttgaca ttggaaggct tgattacccg gcaagatgta atgaaagcga tgcagcttgt
    10561 ccagcgacaa ccgcagattg cagatacgat ttcggatcag atatctggaa atatccatac
    10621 gattgatact gaccgtgaag gaaatcgttt ggaaaaccct aagttcaaat tcgtagtagc
    10681 accacaaatg gtcaatggcg ttggaaccat ttcttttggc gtacttagcg aaatcatttc
    10741 tgatgtcgca caaaaaacaa tggtgatgaa ccaaaaacga aatatcttga ttgaacaagt
    10801 gaacctacat tatttgcggc tgatccaatt ggaaagcgaa ttagacattc gtccacgtgt
    10861 attggaaatc ggcagacgtt ccgctaaact ggatatcgaa gtgtttattg aaaacaccat
    10921 cgtttccaaa gcaatcgttg tttgtcaagt aatggaacgt tcttagaaag caggagtgaa
    10981 atgacagtac agcaagaaat agtagataca ataaaaaaat acgataaaat cattatccac
    11041 aggcatttgc gccctgatcc tgatgcatta ggatcacaag taggattagc cgaactatta
    11101 cgggaaagtt tcccagaaaa agaaatacgt caagtaggtg aaacgattga agggcttcgc
    11161 tttttagcag aaatgcaaga agttgaagat gtcttctacc aaggagcgct agtcatcgtg
    11221 actgatacag ctaattcacc cagaatcagt gatcaaagat atcagttggc agaaaaactg
    11281 atcaaaatcg accatcatcc caatgatgac ccttatggag atcttgtgtg ggtaaataca
    11341 aaagcaagta gctgtagtga gatgattgca gaatttgctt tgatgtttcc tgaatcttta
    11401 aagatgaacg ttaaggctgc acggttactt tatgcaggaa tcgtcggaga tacagggcgc
    11461 tttttgtatc cctccacgac gtcccgtaca ttagagattg cttcgatatt gagaaattat
    11521 ccatttgatg caagtgcttt gaacagagag attgaacaaa tgccgatgaa agtcgctaaa
    11581 ctttccggtt atctttatca aaatatccag gtggatgaaa atggtgcagg aagaataatc
    11641 cttccgcaag aaattcttga taaatatgga atcgatgatt cagagacagc ttcgatcgtt
    11701 tcacttcctg gagtgattga cgaagtgctg gcttggggga tttttgttca gcagccttca
    11761 gggtattacc gcgtacgttt acgttctaag gggccgatca tcaatgaatt ggctaaacgc
    11821 catcatggag gaggccatcc attagcaagt ggtgcgaatg caaaagattt agcagaagta
    11881 gaggaaatct ataaagagat ccaagatata tgccaatcgt ataagagcag aaaaacagaa
    11941 tgatacttcg ttcgaaaacg tgccttttgt agtaaaaatc acaaatgtat cttttcaaga
    12001 tcttcttttt ccgttacaat agtgctcact aaagatttta aaggagaaag aagatgacat
    12061 taccaaattg cccagaatgt ggctcagagt acacatatga agatcgaggc ttgttgattt
    12121 gcccagaatg cgggaacgaa tggaacaaag aagaacaaga aactgtcata gaagacggat
    12181 tagtggtatt agatgcaaat ggaaaccgtc tgttagaggg cgatagcgtg acagtgatta
    12241 aagacttgaa agtaaaaggt gcgtcaggtg ccattaaaca aggaacaaaa gtcaagaaca
    12301 tccgtttagt agaaggcgat cataatatcg attgcaaggt agaaggattt ggaccgatga
    12361 aactgaaatc ggaatttgtg aaaaagaatt aaagaatatt caaggtcttt tcacattctt
    12421 ttcctactac taatgataaa ataaagtaaa cgaaaaggag tgaaacgaaa atgtatggtt
    12481 atggaatgta tggtttttta gatccgacat ttcttttggt cattcttgga ttagttattt
    12541 ccggaattgc gtcagcgtac gtcaatagta ctttccgaaa atacgatcaa gtgagaagca
    12601 aaaacaatgt gactggtaca caagcagcac aatatatatt acaaagtcaa cagataaata
    12661 atgtcggtgt tcaacaaatt gccggagatc tcacagataa ctacaattca ggtaataaga
    12721 tgttgagttt gtctcaagca actgcacagt ctacttcagt tgctgcgata ggtgtagcag
    12781 ctcatgaatg cggacatgcg gtacaagatg cttcgggtta tgtcccattg aagattcgtg
    12841 cagcacttgt tccagcagct aactttggtt cgatgatttc gttccccttg attatggtag
    12901 gtgtattgct tagctggaac tctacgttaa tcaatatcgg gattttcgct ttttctttag
    12961 cattactttt ccaattggtg acattaccag tcgaatttaa cgcgtctcgg cgagcaatcc
    13021 aaattttgag tgaaggcgga ctactgacgg aagaagaagt accgatggca agacacgtat
    13081 tatttgcagc agcactgact tatgttgcag cagcgctttc gacattcctg cagctgttgc
    13141 gcttgatctt attgttcggc ggcaaccgaa gagattaaaa taaagaagtt gtgaaatcag
    13201 cgctttgatc tgagctaata ccgagagtta gctgattgaa taccatttat ttggaa
//
LOCUS       DAZKCH010000074        12809 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000074 DAZKCH010000000
VERSION     DAZKCH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.075"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..177)
                     /locus_tag="ACG84X_002208"
     CDS             complement(<1..177)
                     /locus_tag="ACG84X_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9128041.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYD"
     gene            319..933
                     /locus_tag="ACG84X_002209"
     CDS             319..933
                     /locus_tag="ACG84X_002209"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9128042.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            1122..3002
                     /locus_tag="ACG84X_002210"
     CDS             1122..3002
                     /locus_tag="ACG84X_002210"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9128043.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            3081..3308
                     /locus_tag="ACG84X_002211"
     CDS             3081..3308
                     /locus_tag="ACG84X_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFP9128044.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            3313..3855
                     /locus_tag="ACG84X_002212"
     CDS             3313..3855
                     /locus_tag="ACG84X_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFP9128045.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            4082..4798
                     /locus_tag="ACG84X_002213"
     CDS             4082..4798
                     /locus_tag="ACG84X_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFP9128046.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(4858..6693)
                     /locus_tag="ACG84X_002214"
     CDS             complement(4858..6693)
                     /locus_tag="ACG84X_002214"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFP9128047.1"
                     /translation="MQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLL
                     LLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVSPVL
                     LIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSP
                     SFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYN
                     TKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLM
                     LSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHP
                     FTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNT
                     ETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKF
                     IQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNK
                     EVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTE
                     DSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(6889..7887)
                     /locus_tag="ACG84X_002215"
     CDS             complement(6889..7887)
                     /locus_tag="ACG84X_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128048.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            8106..9326
                     /gene="sstT"
                     /locus_tag="ACG84X_002216"
     CDS             8106..9326
                     /gene="sstT"
                     /locus_tag="ACG84X_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFP9128049.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            9473..10108
                     /locus_tag="ACG84X_002217"
     CDS             9473..10108
                     /locus_tag="ACG84X_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFP9128050.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            10299..11039
                     /gene="truA"
                     /locus_tag="ACG84X_002218"
     CDS             10299..11039
                     /gene="truA"
                     /locus_tag="ACG84X_002218"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFP9128051.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(11184..>12809)
                     /locus_tag="ACG84X_002219"
     CDS             complement(11184..>12809)
                     /locus_tag="ACG84X_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128052.1"
                     /translation="KNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLSRIIG
                     LDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFITFLT
                     MVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLILMGCY
                     EIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLLSLLK
                     ATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYTIGLF
                     LFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVWRLNG
                     FSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLTLIAP
                     EDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIELDNSN
                     NKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTKLAIA
                     SRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
BASE COUNT         4284 a         2034 c         2508 g         3983 t
ORIGIN      
        1 atcatataga tcatagatat ccttataatg tgtataaaaa gtcgaacgat gtacatctgc
       61 cgtttctgtt agttcgcgta tagtgattgc ttgaatcttt ttatttacta ataatgtgga
      121 tagtgtttca gccaaagctt tttctgtttt tttgacgcgt ctatctgtct ttttcattta
      181 cctatctcct tatccgacat atcaaagcaa agctgtcgct taatcgacaa acttatagat
      241 gattgattat agatagtaga cactgtgtct attataatgt aagtataaca caatcattga
      301 agttgaggag gcgaaatgat gaaactaact tttaaaccct tagaaaagaa agattacaaa
      361 aaagctatct attttgctgt tgaaggaatg aactttgaga gatatatgga aaatgaactt
      421 ctgctgaatc tttacggaag atattttttg tatatggagt tgaatcgagc aactcaaatt
      481 cttgctttgt atgcagagga cgagttggca ggtgttttgc tggcggagat aaaaggagaa
      541 aaaaagaaac atcgttcttt tggacagcaa atatatgtta agatattcga ttttttacaa
      601 aatatatttg ctaaagaaag taaaggagct tacgagacag caaatgaaca aatgcttgca
      661 gcatatttaa agaagcattc gccagatgga gagatcattt ttttagctgc aaatcctgat
      721 ttgaaaacaa aaggcatcgg taccaagttg ctaacagaat ttgaaaaaag agagaaagga
      781 aaagaaatat tcctttttac agatagtggc tgtacgtatc aattctatga acgacgtgga
      841 tttgaaagac taaaggaaaa aattagcaag ataaaaatct tagataaaga aatagatctc
      901 cgatgtatgc tgtacaggaa aatcattcaa tgaaaatttc gatagaaacg acaatagttg
      961 gcaagatcac ttttagtgag tcttcttgct aactattttt tgtagtgtat tctaccaaaa
     1021 gaaaaccgcc tttttgacta aacttgatag tggtcaattt tttatgatgg ataagtatct
     1081 atacttagtc tcgtaagaat gaaaggaaaa gagggagaaa gatgaaatta caaaagtgga
     1141 tccaagagca tcgaaatcat atcaccgcct tatcagctgt gttgattatt tttggtttta
     1201 tcggaaaatt tactggtttt gtcttgttct ataacattgc tctagccata gcttctatta
     1261 ttgcggtcat acctattatg atccatgcgt atcaggcagt gaaagtcaaa gttatctcaa
     1321 ttgatttact cgttactatt gctgtgcttg gtgcctttat gatcggagaa tacaaggagt
     1381 cagctatcgt tacattcttg tttttgtttg gtagctatct ggaacaaaaa acattgacca
     1441 aaacgcggga gtcaatcaag gctttgaccg agatggcccc atctactgct agtgttgtcc
     1501 aagaagatgg aacgactgaa gaagtggaaa tcgatgacgt ggaagaaggc gatatcgtct
     1561 tagtaaaaac tggtggagct attcctgtgg acggacgagt cattgacggg aaagggtatg
     1621 cggatgaagc cgcagtgact ggtgaatcac gacaagtcgt caaaatcagt ggagatgaag
     1681 tcttctctgg aacgatttta gcagatggct acgtgacgat tgaagcaact aaggtcggag
     1741 atgatacgac ctttgccaaa attatcgaat tagtagaaga agcacaagat accaaatccc
     1801 atgcggaaaa attcattgat cgattttctc agtattatac tccaaccgtt ttacttattg
     1861 cgttggttgt tggtctgatt agtcgtgatt ttcgtttagc aatcactgtt ttggttcttg
     1921 gttgtcctgg cgctttagtc attggtgcgc ctgtttcgaa tgtagcagga atcggtaatg
     1981 gagcgaaacg gggcatctta gtcaaaggcg gtgaagcaat ggatactttt tccaaaatcg
     2041 atacttttgt ctttgataaa actggtacat tgaccaaagg aactactgct gtatccacta
     2101 tcaagaacta tacagaggat gaaggggaca gcttagcttt agtggctcga ttagaaacgt
     2161 tatccgatca tcctctgggg cgcgccgtga tccattatgc tcaggagaaa gacattgatt
     2221 ttcaacaatt agcagtcaaa gataatcaga caatcaaggg acaaggaatc acagctgaga
     2281 ttgatggtca tacagtttgt gcgggcaaca ccaaattgat tgccgctcac aaactttctc
     2341 tcacaccaaa gcaagtacaa gatttacatc aattacaaca aacaggcagc tcggtcatta
     2401 ttgtagcaat cgacaaaaaa atcactcaaa tcataggtgt gtcagatgtg attcgaccag
     2461 aagtcgctga acaattagct aagttgaaac aagcaggagc aaaacagtta gtgatgctga
     2521 caggtgataa tcagatgact gctgattatg tagctgatat gttaggcatt gatgaagtcc
     2581 atgctgaatt attaccagac gaaaaggttc aatttgtgaa aaaataccaa gaacaaggat
     2641 tgcgcgttgc ttttattgga gatggaatca atgattctcc ctctttggct gcggctgata
     2701 tcgggattgc tatgggatca ggaacggatg ttgctatcga aacgagtgac gttgtcttga
     2761 tgcaatctaa ttttgaatcg ttggttcatg cctaccgctt ggctaagaaa actgttttaa
     2821 atacccgtga aaatgtagtg attgccattg gtgtcgtctt atttttactc aacggcttat
     2881 ttgccgggtt tatttacatg gctagtggga tgttcgttca cgaagctagt atcttgatcg
     2941 ttatctttaa cgcgatgcgt ttattgtatt ttggacacga aagcaaagaa gaaaaatcgt
     3001 aaaacttgat aagaatcaat ttttttatgg aagctgtaat ctagaataag actatcaaga
     3061 aaaaggaagg aagaactacg atgaaaaaaa ttattatgca attagataca ctagcttgtc
     3121 caagctgtat gcaaaaaatc gaacatgcgg tttctcaaca gcctggggta agcaatacga
     3181 aagttttgtt taatgcgagc aaaatcaaag caaactttga tccagatgaa gtccaccctg
     3241 aacaattagc tgcagttgtg gaaaaattag gttatgaagt ccaatcagca aaagtaaaag
     3301 aggcgtaaat caatgaatat agtggaagaa aaatttgttc aagaaacaaa acaagcagat
     3361 atcgaccatc ataaaccaac tgctggcgcc atggtggggc atgtattagc aaattttaaa
     3421 ttagaagaaa tgaaattgat ccaagcacaa ttgtatgttt tgggtacatc ttcgcaagaa
     3481 ttaagtaccc ttttttcaga atatgctgat caagaagcga gatggttcaa taaaatctct
     3541 catgagttag tgattgaaaa tgaaatcgtt ccgtctactt tagaagaagt catgcgttat
     3601 ggaaaaattt acgaacatgg tcaaaacaaa tatttaccag cctcaacaat gttggaaaac
     3661 tttgcaaaag attttgattt ccaaaatgtc tttatcacac gggcaatcaa attagctgaa
     3721 aaagaagaaa aatatggctt gcaacaattg cttgttgaac ttttaagttt caataaagaa
     3781 atcatctacc aagtacaaag actccaagga aaaactgtcc gacaagattt ggatgaggaa
     3841 gacgatgatg actaaaagtc tatgtttctt caaatacaaa tataaagcgt gaggtaaatt
     3901 ggaaaatcac gaagattaaa ataaaagaag cacccgctga tgtattacag acaacatcag
     3961 cgggtgcttc tcagttttta gaagatttga aagattgatg agaaaatacg aaaaatcaat
     4021 aaaatcacat tgcttatttg atagaataaa gaagtgggag taatcgaaag gagtttttta
     4081 attgaaaaaa aggattttag taacaattgg tctagctttt ttgttagctg gttgtaccaa
     4141 cgggaatgaa tcgaaaaaag aatcaacaaa agaaacagcg aaagcaacag ttgcaactac
     4201 tacaacaact agcacagaga gcaagtcaac tgcagcaagt acagaaacag cagatacctc
     4261 tacttcgtca gagtcttcca aaacgactga aacaactcaa acatctactt caagttcttc
     4321 tgtagaggct tcatcttcct cttcagaaag cagcgaacaa gttgaacaaa cactgtggaa
     4381 tgcagacaaa tccgcacaat tagaggcatt tatgaccaaa tggggccaaa caatgggaca
     4441 acaatacaaa agttatacga atcaaatgag tgtggactta tatggtctta aagtccctca
     4501 agctattttg aacggggagt ggaagatggc tattggtgga gtgcctgttt ctgcagaatg
     4561 gtcagaaagt gggacaggtc aagcagacta tcaaatcaca gccgtctatt ccgatgcaga
     4621 gacagaacca tatctgaaaa agcacgtcta tctattcggg tttcagcaaa atcagccaaa
     4681 agtattggtg acacaacaaa atcaggggaa tcccgataat tatctttact tcaacgagac
     4741 agcgaataat gaattgaaaa atggctttaa tcaaatcgtt tatggacaag caaattaatg
     4801 agataaacaa ggggttgtga catgtctttt atcacaaccc cttgctcagt ttatttgtta
     4861 gtcttttatt ttttgtgtcg cccatgttgc actgtactgg ttacctgcaa caagatcata
     4921 ttgtatcaga cgataatctt ctagaatttc tttttgtttc tcagttaaat ttttttcttg
     4981 gataatttga ctatcctctg taacaaagac ctgttttcca ttaaaacgat tagacaagct
     5041 ttctgtagga tcaattgtta atgcaggtag atgattagat acttctgtca acaacgcata
     5101 gtaaggagtt actttgatat tcgcatgctc aagagccata gcaccaaagt tattaggagc
     5161 aacaacttct ttatttaacg tagctgcttg ttcacgacta tacttgttgt tataaatgaa
     5221 ataatctgtc tggtgctgtt ctaatccata ttttttcgaa tcattcccac tatagattgc
     5281 gggtaaatgg tcaccataaa aaacaaaggt aatcggttta tcgattttgt cgatttcttg
     5341 gatgaatttt tttactgctg tatcggtata gtgaaggcct tgcatataag tttgtaattc
     5401 ttttcttcta ttaggaatga cagcagttcc ttcagcagtg tagttcaatt cactatagta
     5461 atcatcataa ggcatatggt tttgcatagt ggataattgg atgaattgtg acgtttccgt
     5521 attgctttgt aaagctttca aggtttcttt gtatgctgaa tcatccgata tgcgtgggct
     5581 ttgttctatt ttatccgtat aagttaattt atccggactg tctaaataat agaacctgtc
     5641 aaaaccaaat ttatcaaaca cttgttttct gcgataaaga gcagctgtaa aaggatggat
     5701 ggctattttt tcatcgaata gatcggtaat atttggactt attttctgac gctccactag
     5761 ctgggtataa ggtgtaacta acgaagcaga caggttactg atactcaagc ctgtcagtcc
     5821 ttcccattcc atgttagctg ttccgccacc ataaccgacg gataacatca atcctcctgt
     5881 tccttctgtt ataatgcttt tgatgtaagg aatagggtct gtaggtactg tcagattagg
     5941 gacacgtgca ggatcactga agctttcact taaattgaga acgatcgtct gattgtttaa
     6001 ccagtcactt cttgtttggt tgatttcatc tgcctttgtg ttgtactttt tcattattcc
     6061 attaattttt tctttcgaat agccagcagg ttcttccatg attttaatgt cgatattgtt
     6121 taggaattga atgactggtc cgttatcttt tacggcgcct tgctggttaa agaaagtctt
     6181 gtttacttta aataaattaa acagcaagaa agaaggcgaa tttttgtgat taatgaaaaa
     6241 gacacccgaa aaacatccta ataatacagc gatactgata aatcgacgtt tccaatgaat
     6301 cttcaaggaa tactgttttt gtagtctacg ttgtacaata atactagtaa tcaataatag
     6361 gagaaggatc aatccgccca cgattaataa gactgggcta accatcgata atagttctga
     6421 caatccggtc agcattttta aatctgaagg aaagacaggc tcttcccgca tttccatttt
     6481 gattactgtc gaaatagtga gcagtaagtt aatgatcaag gtagcagtca aggcgtacca
     6541 aaaacgattg gaaatcaaca atagtaagaa gaaaaatccc ataataatga tgattgtcag
     6601 gatcatgggt gcttgtcgct gagtaaatat ttttaaggca acctggatag tttctttcca
     6661 accttctttt ggttctaaaa cgaaaatctg cacgaaggta aagcagtaaa aaaatgctgc
     6721 aactaaaaaa taacttttat gaacaaaaag ccaatgaatt ctttttttcc aacgctgagt
     6781 taattgttca atcgaatcaa aagcgaagta ttcgatgaaa cgatgaatga aacggatttt
     6841 ttgtatataa aataaaaaga taactaggag ggacactgct aataaatatc aaataaaaaa
     6901 ctgcccgata tttatcagcc atgccttccc tgagtttgga aattcacgtt tcataaatgt
     6961 agatacgcga taagaaacta aagggaaatt acatataact tgagtgacaa tcaaaaatac
     7021 agcaagaaaa tttcctcttc cttttatacc taatttatca gatagcattt ctaaaaataa
     7081 aaacgaagag aaagtataat acattgcgaa gagagaatat ggtttagaaa acctcagcgc
     7141 tgtatctgta tttcctctga tgatgagtga aatttgtgtc atcaaaataa tcaaaccgaa
     7201 taaaacaatc aagctgataa atacttgagg aagcttatag cggacctttt ctttccagtt
     7261 ccattctttc aaaccataac ccattaaaaa taaataaaaa atccataaaa tactctgtcc
     7321 attctgtaat gcaaacgggt ctttattaaa tagagtagag cagccaacta atccaattgt
     7381 taaaaataat agtagatatt taattgttgt tttcgataat ttatttaaaa atccaactgt
     7441 ataaggaata ctacaaaaaa gcaaagtaca agaaacagca taagtaaagt aattctgact
     7501 gataggtgtt aggataagcc aataatcacg aatattcaag ctgccagctt gtacgtaaaa
     7561 aaagatattg caaactagtg tggctattag gaatataaag gcaaaacgac ttaaataatg
     7621 taaaactttt aaacgggcga ttttttgata ttggtaaccc atgtaaagtg ggatcaaatt
     7681 tgcaccaata acaacggaag tttgtaaaaa tgtatagatg tagaatcgac cagggtttgt
     7741 tgcatatgta ggaatagtga ctgctgaaat caatatacgc tgtaaaacca tcattataca
     7801 agcgacaaag attgtcagga agccataact ctccttcttt atttttttca agaataaaca
     7861 cctcacaaaa aaattggaca aaaacataag aaaacgtttc ctgataagtt gcccattaat
     7921 aacatcctaa cttagaatat ctcaaaaaac aacgtgtaga cagaaaaagt acaaaattag
     7981 caagaaatgg ttgtttgtat tgttagaatt tttagaaaat tataccttta gtttctttgc
     8041 ataaaatgat acaatgattg ttaaaattgt gaaagggtgg tcatttgtta gagaagtttt
     8101 tggatatgtc gttagttcaa cgtattgttg ttggtatttt agtcggaata ttgtttggta
     8161 tctttttccc cacatggaca tttatttcaa tattgggaac gttgtttgtc agttgcttga
     8221 aggcaatcgc acctattctg gtttttttct tgacgatggc gtcaattgcc aagcataaaa
     8281 ttgggaataa gacattcgtg aagcctattt tgatcttata tttagtggga acattgcttt
     8341 ctgcacttgt agcagttatt gtaagttcaa tttttactgt tcctattact ttacaagaaa
     8401 cagtatctga aaaagcaccg caaagtttgg aaagtgtttt atctactatg ttgacgaatg
     8461 tcacacaaaa tcctgttcaa tctcttattg atgcgaatta ccttggcgtc ttattctggg
     8521 ctgtattgtt gggactagct tttcgagcac gttcagaatc gacaaaagag ttggtggatc
     8581 agatatctat agcgttgtca caagtcgtac aagtgattat tgcatttgct ccgataggga
     8641 ttttaggatt ggtttatcaa tcaattgcta cgactggaat cgctggattg gcagagtatc
     8701 tgcagctttt acttgttttg atcggtacga tgctgtttgt cgcattagtt gtgtacccat
     8761 tcctcacgtt tttgtttatt aaagaaaatc cctatccatt gattttcttt tgtttgaaag
     8821 aaagcgcact tcccgctttc tttacccgaa gttctgccgc aaatatcccg ataaacatga
     8881 tgttggctga aagattgaaa ttgacaaaag agtcttattc catatcgatc ccgttaggtg
     8941 ctacgatcaa tatgggcggt gccgcgatta ccatttcctt gatgacgttg actgctgtac
     9001 attctttagg gattgaagca ccttttgttt tgaaagtcct tttatgtatt ttgtctgctt
     9061 tagctgcttg tggagcttca ggtgttgcgg gcggttcact gttattgatt ccattagcat
     9121 gtagtttgtt tggtatctct aatgatgtcg cgatgcaaat cgtcggtatt ggatttatta
     9181 tcggtgttat ccaggattca atggaaactg ccttaaattc gtcaagtgat ctgttgttta
     9241 ctgcaatagg agagctaggc gcgcgtaaaa gaagtgggga aaaaatcaaa ttgaaagatt
     9301 gtttagatgg attaagtgaa cgttgaacgt tagatattta gtatttttaa aatgattcga
     9361 gtttttaatg agttatatag atgttcgtgt aaatagaggt ttctgttaaa tcaagataaa
     9421 gtcgtttata ataacaatta aaagcatagg taattgttat tggaggcgta tcatggattt
     9481 tttacgtaaa tttggttttt tctttttatt attaggcgtg ctgagtgatt ttttgactcc
     9541 gtacgtatta ggattgtatt atcctgaatt agatcaaatg aagagcgtga tcagtgtatt
     9601 tggagaggtt tccagtcctg taagaaaagc gtttcttatt tggtctgtgg tttcagggat
     9661 ctttttcatc ctgtcattgc ctgcattgta tgctgcattt gttagtacat ctcgtgtgtt
     9721 agctacccta gttacagcag ccatcgcgtt ctatggtata ggtgattgta tctttacagg
     9781 tttgttcagt atcaataccc atgaatcttc gtggaatgtc tcgacatggg tccataatat
     9841 cggatcaggt ttaggttaca gtggtttttt attgtttcca gttcttcttt tcttgatcta
     9901 tcgaaaaaat gggcaaatgg acgtaagcca cttatacctt ggactgtctg tgatcagttt
     9961 gctttttgcg gcgatttatg gactggcaag aattccttct ataaattctt ggccattact
    10021 gaataaaata ggtttttgcc aaagaatcag ttttttcttt aattatgtgc ccattgcctg
    10081 gttgagtatc ttgcatctca aacagtaaaa cttgagccgt caaattgaac agtcagcgga
    10141 tacttcatcc ggtggctgtt ttttgttttt ctgaaatata tatttccaca gttttcttgt
    10201 atagcttctg tcttagagaa gcaaggagct atattttgtg ctacaatctt aaaaaggtag
    10261 agagaagacc aaatggaaga cagaggagcc actaaaatat gagaaacatc aagttgacaa
    10321 tcgaatatga cggaaaaaga tattcaggat ggcaaagact tggagatgac gataaaacca
    10381 ttcaaggaaa aatcgaaaaa gtattgcatc agatgacaaa tgaagagata gaaattattg
    10441 gatcaggaag aacagatgct ggcacccatg cgcgaggaca agtagcaaat tttaaaacaa
    10501 acacagaaat tggactggca gaaatgatcg actttatgaa tcgttacctt ccgcgggata
    10561 ttgtcatcaa aagaatcgaa gaaatgcctg agcgcttcca ttcaagatat aatgcggtgg
    10621 gcaaaaaata cagctattat gtttggaaca acgtgattcc ttcagcattt gagcgaaacc
    10681 acagctttta tttccctcaa gagttggata tggacaagct gaatgcagct tgcgaaaaat
    10741 tagtgggtac acatgatttc attggttttt ctgcattgaa aaaatcaaaa aaatccacag
    10801 tgcgtacgat tgatgaatta tctatcgaac gaaagggaga aatgcttcat tttacttttg
    10861 tcggagacgg attcttatat aaaatggtgc ggattatcat ggggacatta ctagaaatcg
    10921 gcacaggtgc catgccgata gaaacaatcg atgaaatatt tgaaagcaaa gtgcggcaac
    10981 atgcaggaga aaccgtccct gcacaaggtc tgtttttgga tgaagtttat tatcgataaa
    11041 aatactttga taatggatga aacgcatgtt tcacagtata aatatcgatg ttaaataatg
    11101 tatgaagcaa attaaagaaa tataaaaaaa gactttttag cctgtttatg tgtacagcta
    11161 aaaagtcttt cttaaataaa aatctagtga gaatgttgta cttctcttct cggttgtttt
    11221 tgtttagaaa aagtaaatcg ataaagtaaa aataaaatca aagtaacgat agataaatat
    11281 cttgaagcaa ttgctagttt tgtgtactga taagtaataa cgactttatt tatacctgga
    11341 ggaatagtta attcagttgt gccaaactta gataattttg tttgtactag tttgccatta
    11401 atagaagcca cttgcccttt ataacgataa ataggtgtcg tcaagacagt atttttatta
    11461 ttcgaattat ctaattcaat tgtaagtttg ttactcataa aatgagttgt tggatttatt
    11521 tcctggttac ctagtaaata ttgatcatta ttaatcatat caggatgata gattgactct
    11581 ttgtttgcat aatcagtatg attgtaattt tcagctatag caacagcgtc ttcaggtgct
    11641 ataagtgtta atgaatcttt gttagcatgg atagaattgc ttactcctga gagatgcaat
    11701 attagtgcaa gaaacgtaaa gaccattatt ttccatgaat tatttttagt agaaaaaata
    11761 taatagatca ctatactcat cgtataggct ataaataaag aagaaaaacc atttaaccgc
    11821 cagacaaatt gtagactctt aactggtgta tggttaaaaa gttgccaagg aaataaattg
    11881 gttgaacaaa aaagaacaaa tacaccaaga aagaaaataa ataaatcatc agcagttaat
    11941 ttttttataa aaataaaagc accaatcaat ccgagaaata agaataatcc aatagtatag
    12001 ttgttatagt tattatttaa aatatgtgtc agcatatcac taggagccat accacttaat
    12061 tcttttccca gtgggacttt caattcttgt gctctagatt gttgaataaa aggaattaag
    12121 aatcccgcac ttaaaaaaaa ggtgaggacg gtagctttta aaagacttaa gagtctagcg
    12181 attttttggt cccaaaaata aaaagaaaga aacaacgttc ctccaataaa tacagaaacc
    12241 atagcgacag aaagtaaatg agtatacact actagcgtca tgccaataga caaccagtac
    12301 catttttggt aatctctaat ataaatttcg taacacccca ttagtatcaa aggcaaaaat
    12361 gttaaagcga cagcttctcc caatgaagca cgatggaata tgtcaatggc acgataggcg
    12421 gaaaatgtat aaataatcga aaataacagc gaaatataac gattgttttt tatttgtttc
    12481 atagaaaaat aagaaacgac cattgttaaa aaagtgataa aaaaatagta gatattataa
    12541 cttaaaacaa gatttcccat cattttataa aataaaaaag ctggataaag agtaagccat
    12601 ggataaaaaa tattcatcat tgttccatga tgatcgaagt tattgaagtt tactggagaa
    12661 ctccatacat tatctagtcc tatgattcga gataaatgaa agtaagtatc ctgattgaca
    12721 ctatgataga ttcccttaga catgaataga gggatgacgt aagcaaaact tagaaataac
    12781 ataaaaatga tatctattat ttggttttt
//
LOCUS       DAZKCH010000075        12742 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000075 DAZKCH010000000
VERSION     DAZKCH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.076"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACG84X_002220"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACG84X_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFP9128053.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="ACG84X_002221"
     CDS             complement(323..892)
                     /locus_tag="ACG84X_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFP9128054.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="ACG84X_002222"
     CDS             1078..1980
                     /locus_tag="ACG84X_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFP9128055.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACG84X_002223"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACG84X_002223"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFP9128056.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACG84X_002224"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACG84X_002224"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFP9128057.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8323)
                     /gene="dnaE"
                     /locus_tag="ACG84X_002225"
     CDS             complement(5003..8323)
                     /gene="dnaE"
                     /locus_tag="ACG84X_002225"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFP9128058.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSK
                     SIKGQLIYLLGEDNVVFK"
     gene            8554..8739
                     /locus_tag="ACG84X_002226"
     CDS             8554..8739
                     /locus_tag="ACG84X_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFP9128059.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8801..9997)
                     /locus_tag="ACG84X_002227"
     CDS             complement(8801..9997)
                     /locus_tag="ACG84X_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFP9128060.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10167..11603)
                     /locus_tag="ACG84X_002228"
     CDS             complement(10167..11603)
                     /locus_tag="ACG84X_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFP9128061.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11896..12705
                     /locus_tag="ACG84X_002229"
     CDS             11896..12705
                     /locus_tag="ACG84X_002229"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9128062.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3804 a         2675 c         2250 g         4013 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttactcttgc tgtcatccac ccaataagca tctgacagaa
     5101 ctacttttcg ttgcgttttt tcgtgataca taactactgg tatatatcct gggtgtttct
     5161 gaaaaatcac ttgtaattgt ttcattatct cgggatcttc ccgttcttct gtaatacgca
     5221 aatagcaagt ttgtgaagga tactgggctt ctaactggtt aggatcagca aagctttctc
     5281 caattagttg cagttcctga ttatatttgc tgatttcgct ccgcccttga acaaagatca
     5341 ctcgatcaac ggcaaacaaa ttacgatatt tacgataaag agttggaaaa actgtgacag
     5401 aaatttctcc actactgtcg gttccttcaa caaaggccat cagttctcct ttttttgtcc
     5461 gaatttctct aacttccttg atcatcacta ataaattgac tggttgatta gggacgatat
     5521 ctgtaatcag ctgaacttgt ttagctaaac gaagacgatc aaacccttct gcaggatgac
     5581 ctgacaaata aatacctaag tactcctctt ccagcttcaa gcgttcttct agtgtatagt
     5641 cagcgacttc ttcttctttt aatgccatga ttcccagcaa gtcaagactt ccaccactgt
     5701 aaacgatatt ttggattttt ccttcgagat caagcatcaa ttgtttcctg ttaggagata
     5761 attcatcaaa aactcctact gctgtcagtg attgcagtaa ctctaatttc agccaacgct
     5821 tatcgatccg tatgaggaat tgatccactg actggaacgg gccattttgt tttctttcgt
     5881 ttaatatatc ttctacaaaa tcacgccgaa taccttttat cgctgtcagt ccgaatctga
     5941 tttcttcctt attgaccaac tcaaaactgg aattactttg attaatggac ggcgaggaaa
     6001 gtttgagttt atttttacgt gcttctgcaa tatattcttt caattttgat gtgttatgcc
     6061 gaacagaatt catcaggctg gtaaagaaag cacctggatg atgggctttt agatacgcca
     6121 tttggaatcc cacgaatgaa taagcaaatg catgtgaccg attgaatcca tagtttgcaa
     6181 atttttcgat atattcatat acggtcgctg ctgttttttc cgaatatccc tgttgtaatg
     6241 ctcctgatac aaaatgcgac ttttcttcat ctaatacgtc ttttttcttt ttactcactg
     6301 cccgtcgcag aatatctgac tgccctaatg taaatccagc catagtcgag gcgatctgca
     6361 tgatttgttc ctgatagacg atcactccat atgtgttttt caaaatcggg atcagtgaat
     6421 catctgggta gcgaatggct tcttttcctt tcttcctggc aatgaaggta tctatatttt
     6481 gcatagggcc tggtcgatac aatgcattga ctgcggcaat atcttcgatg ttttctggat
     6541 ctaatcttcg taaaacgttc cggataccag cagattcaaa ttgaaatact cctgaggttt
     6601 cgcctcgttg aaacaagagc agcgtttttg catcatttag cgggatctct tttaatcgga
     6661 tctcataccc ttctactcgc ttaacagctt tcaaagtaaa atcaataatc gataagttgc
     6721 gtagtcctaa aaagtccatt ttcaaaagac cgattgcttc tacctcattc atcgtatact
     6781 gggtcagaaa agcttcatca gaaccgcgtt ggagcggaac tagttcaagt agattcttat
     6841 cgctgataac tacacctgct gcgtgagtcg aaacatgtct tggcaatcct tctaaaatca
     6901 ctgcagtttt gaataaaagt tggttttttt cgcttgcctg aactaattct actaattgat
     6961 gcgaagtttt ataagcttgg gtcaatgtga ttttcaattg attgggtatt gcttttgacc
     7021 agcggtttgc ttcactttgc gataaaccaa acactctagc tgcatctcta agaaccattt
     7081 ttgctgccat tgtgccaaat gttgcgattt gtgccatatg atattgtcca tacttttctc
     7141 gaacataatt caatacttct tcacgtcgat tgtcaggaat atccaaatcg atatctggca
     7201 tcgtaaagcg ttcggggttt aaaaagcgtt cgaacagcaa atcatattct aatggatcca
     7261 catctgtgat ttctaacaca taggctacta atgaacccgc agcagaacca cgacctgcac
     7321 cggtaacgat tttgtttcta tgagcaaaag ccattacatc ccatacgatc aagaaataat
     7381 catcgaatcc catttgatgg atgacagata actcgtagtc caaacgttct tggtattcct
     7441 ttgtatagtc agtgattcgg cgttccactt gcgaatagca taactctctt aaatattctc
     7501 cagcttgttt tccattagga actggataat gcggaagtaa tttctgatgg aactggaatt
     7561 caaatgaaat cgattcagct aaacgctggg cgcctattac agcttgggaa agacccgctt
     7621 tttcgaatcg tttgatcatt tcttgttctg aaagaagata gacatttgct gttagtggta
     7681 aagatgcaga taaattttct aaaggtattt ggcttccctc tttgatatgt ttcatcactt
     7741 caagtgcaaa aagttcttct tgttgtaaac tagcgatggg atgtaatgca caaagcgaat
     7801 aattttcttt tatcacatac tgataccatt caggcaattg atcaggcgtg ttttctgtca
     7861 agccgatata aaaatttcta gtaaaaacat tttcaagtaa aaactgccaa tgaccgaaaa
     7921 agttatcctc tttattgaaa gcctcagaaa cagaatgatt tgccggaaca acaaacgcta
     7981 gatggtcggt ttctgtcatt tctgcaagtt ccaatttttc ttggatcatt tttcggctgg
     8041 aaagtttcat cagctgctga taacctattt catcttttgc gtacgcaagc aagccataat
     8101 ttttttcttc ataagtataa ctaagatgta atccaatgat tggctgtact ccttcttcta
     8161 cacaaatacg atagaattca ggtgcaccgt ataagacatc tttatccgtt atggctaatg
     8221 aagtgtagcc ttgttttttt gcttcttgta catattctcg aatacgtatc gtactttgta
     8281 aaagagaata agaagtaatt gtataaagtt gtgggaaaaa catcttgcat tccgcctttt
     8341 ttttcgttaa aattcactag cgttaaaagg tttgatcctt ttactttcat taagatagca
     8401 ggcgctgaag ttgattattc cacttcattt gcttgcttgt aatctgtagg aatgagttct
     8461 ttcgcaagaa ctcaaatttt attgagattt ggtctcgttt ctttacattc aaagaaaatc
     8521 tggtaaaatt aagatagaaa agaggtgttc tttatgcgat atatcgttac attattctgg
     8581 gctgtcgttc taggtcaagt agtcggttat attggtgctg cattaacaag cggaacatat
     8641 gattttactt tgacaacaat catttcattc attgcgggtg tcattatcct tttgattggt
     8701 gcagttgcgc caagaaaaga aacctctgcc cattcgtaaa aaaacagcca agagcttgag
     8761 atttctcaag ctctttttta ttttctactc ctcaccacca ttataatctg ctgcgaagaa
     8821 ctttacgaaa gttgaataaa gaaagaagaa tatttgacag aacaaacaaa cttgtcacaa
     8881 taaaaacagc actgtaatta taagcatgcg cgactgtcga tcctagcatg ggacctaaaa
     8941 cttgtccaaa gttgctaaac atctgattgt agctatagat tcggctgact ccttcttgag
     9001 gcgtaatctt actgatcagt gtattgacag aaggcatcaa agcgccagtt gaaaagccta
     9061 aaataaagcg aagtatacct aattggagcg gtgtagtgac gaatgccata ggtaaataac
     9121 agcaaaatga taaaatgagt cctccaatta gaactttttg attcccaatc ttatccccta
     9181 gttttcctag tttcggtgaa gaaaagacag cggaaacacc agctatcgaa acaatcaagc
     9241 cgctgacaaa aaggatattt tctgtacttc cgctcaattc acgaatatat aaggtcaaaa
     9301 tagggctgat cgtagtgatt cctatctgta aaatcaaggt cgtaatgaag agaccgatca
     9361 aaatagagag atgatccatt tttgaaaaaa tttctttggt gcttatcaga tcttttttct
     9421 cgattggatg gaaatcttct ttgactaaga aaatggtcaa taccgttgtg atcatcaaca
     9481 aagcccctgt gatcaagaat acattttcca taccaaacca ctgagccagt gcaccgccca
     9541 ttgaaggtcc gatcagattt ccagcaatcg ctccggtaga caatgttcct aacgcccatc
     9601 cgctcttttc tctaggtgcc tgtgaagcaa tcatcgctgt ggcatttgga atatatccag
     9661 acaaaatccc attccaaaac cgcatgatca aaagccaata cgcgtttggt acaaaagcca
     9721 aagatcccat tgttaatgtc atccctgctg ctgcacggat catcatgagt tttcggcctt
     9781 ttcgatcagc tagatttccc cagattggtg caaccacggc agatgcaaaa gcagtcacag
     9841 agattgctag tcccgaaaac aattcgattt gatcttttgg tgttcctagt tgctcaacat
     9901 aaactggtat gaatggcata actaaactaa tacttgcacc agtgaaaaaa cagccaatcc
     9961 acgcaatcac taaatttttt ctccaattaa tctccatcta tcatccctct ttcgtctctt
    10021 ttatcatacc tattttcgaa taaacaagca acgatctcgc cagtaaaaag agaaaaatcc
    10081 cgcaaaggtc attttatatg taacgttctt tttatgtaaa acaaaaagag atcagaacaa
    10141 atactgttcc aatcccttct ctttagttaa attgttgcta gaatgatgaa gttgataatg
    10201 aataaaatat caacgatcca caaagcaaca gaaacttgat tgtattttcc tttgattact
    10261 ttcacaattg tatagaaaat aaatcctgct gcaatcccat aggaaatgct atagcacaat
    10321 cccataaaga tcgatgcaaa gaaggccggt aaagcttctt ccatatctag ccatttgatg
    10381 tctgcaaaag aagccatcat cattactcca actaaaatca atgctggcgc agttgcttga
    10441 tttggtacaa tggcgatcag tggagagaat aaactactta atgcgaatag cactgccact
    10501 actactgaag tcaaaccagt acgtccaccg gccccgatcc cagctgcaga ttcgacataa
    10561 gttgttgtat tcgatgtacc aaagatagcc cccacagaag tagcgatcgc atcggcaaat
    10621 agtgctttat ccatttttgt tttgaaccca cgaccatctt ccaacgcgat ctcgtcttct
    10681 tttgagaaaa tacctgtgcg gcgtcctgta ccgataaatg ttccgatcgt atcgaaagta
    10741 tcagataaac tgaatgcgat gatcgtcatc aatacttgag gaatcttgga agaatcactg
    10801 aataaagatt gcatgccttc agaaccaaat gctgcaccga aagttgttcc taattcttta
    10861 aatgaattac ctaacgaatt cgtttgccaa tcaatggaac ttaaatcaac aacacccata
    10921 aaaataccaa ggactgtggt cgctacgata ccgataagaa tagccccacg gacatttttt
    10981 acaactaaaa tggctgtcag taccaaacca atcacagcca ataagatagg agcgttgtca
    11041 aagttggcta acgcagggac gattccacca tttatcgtaa catttgtcgc ttttccgcct
    11101 tcaacgacag agctcgaaat agctgactgg tctgctgaaa aagataagaa tcctgcattt
    11161 ttgattccga catacgcaac gaaaataccg atcccgccac caatcgcatg ttgaagactt
    11221 tcgggaatcg cccgaataat catttttcga atatttgtga cagtaataaa aatattgatt
    11281 aatccgcaaa taaacaccat tgccaaggct tgttgccaag aataaccaag cccaaaaacg
    11341 accgtaaaag tgaaaaatgc gttcaatccc ataccaggtg cctgagcata tggtacattt
    11401 gcgaacaatc ccattaccag cgtaccaata atcgatgcaa tgattgtcgc tagaaatact
    11461 gcttggaagg gcatacctga tgctgacaaa atcgtcggat ttacgaataa gatataactc
    11521 atggcaaaga atgtcgttac tcccgccatt atttcagttg atacatttgt attgtttttc
    11581 tttaaaccga aaaacttttc cataaaaagt tccactccct gaattttttt ctgatggaaa
    11641 actataataa taaaaaataa gtaaaatagg gcaaatccat cgaacaattt caaattatat
    11701 agacgtttca ttcgcttttc aacgtttttt taacaaaaaa agcgaaaata atacttaacg
    11761 ttcgtgttta gcttatgttt agctatttat atagccataa ctgtagtttt tgttaggaat
    11821 agctgattgc tcttgttaat tacctaaaat atgctagact aaaacaaatg ctagttgagg
    11881 aaggaaggac ccttattgaa taaaaaatta attgccatcg atctggacgg aactaccctc
    11941 aatcaagatt cgatgattac atctaaaaca aaagagactc taaaaaaagc aatcaatgcc
    12001 ggtcatcatg tcagtattgc tacaggacgc ccattccgaa tgagccatca gttttaccaa
    12061 caattagaat taacaacacc gatggttaat tttaacggcg cattagtaca catccctaat
    12121 cagcactggg atggtgaaag agaaacgttg atcaatcgtg aaatcgcttt tgaaatctta
    12181 tcgcaaaaaa agcagctaaa tttagatttt atcgctgctg aaaatcgtga tacttttttt
    12241 attgacagtt ttgatttctt tgatgaaaaa atttttgctt cttctcgtcc aggagagaag
    12301 aatttgcttt ctcctaaaaa tttgacgaca aatcctacat ctttgcttgt ccgaacagac
    12361 aaacgttttg caggagctgt atctgctgaa ttaacacgtc aatttggcag ttatgtcgat
    12421 gttcggacat ggggtggacc tactgccatc ttagagattg tttcaaaagg aatccaaaaa
    12481 gcaaaaggcg tgcaagagat tgctaactac ctgtctatcg atcaaaaaga cgtcattgcc
    12541 tttggtgacg agcataatga tttggaattg ttggattatg caggttgggg agtagctatg
    12601 gctaacggta ctgaccaact caaaggcatt gcaaatgatg tcactccttt gagcaatcag
    12661 gaagacggtt tagctgttta tctggaaaaa ctacttaaac tataatagag aattagattc
    12721 cacaaaaaag aggttgtgac aa
//
LOCUS       DAZKCH010000076        12493 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000076 DAZKCH010000000
VERSION     DAZKCH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.077"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..375
                     /locus_tag="ACG84X_002230"
     CDS             <1..375
                     /locus_tag="ACG84X_002230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128063.1"
                     /translation="VKDNRNSIRKEVLHLIKFVKKTVAIPSEKKINESTRKLYRRANK
                     KALKLSAFLSSLSLKLSLILFISEHVSITDFLNLAKNPYLKGVRSILWQGLQSLACLE
                     VRTWFSYSSCRKIFLMMILSIN"
     gene            complement(324..893)
                     /locus_tag="ACG84X_002231"
     CDS             complement(324..893)
                     /locus_tag="ACG84X_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFP9128064.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(967..2256)
                     /locus_tag="ACG84X_002232"
     CDS             complement(967..2256)
                     /locus_tag="ACG84X_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128065.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESENKSKLTKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQAFAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            2514..3458
                     /locus_tag="ACG84X_002233"
     CDS             2514..3458
                     /locus_tag="ACG84X_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9128066.1"
                     /translation="MEEKIEESKQKIDQLIQELEKAVIGKRSTIQLMIVALLAGGHVL
                     FEDIPGVGKTLLVKALAKAVQGTFSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPI
                     FTTILLADEINRTTPRTQSALLEAMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTY
                     PLPEAQLDRFLFRLQIGYPSFDDELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANV
                     FVSPEVASYALQLVSATRSHAAIQLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQD
                     LVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQIPVPVR"
     gene            3472..4545
                     /locus_tag="ACG84X_002234"
     CDS             3472..4545
                     /locus_tag="ACG84X_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFP9128067.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKREISFPVTVL
                     PAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKLSAHTQEWLY
                     REYDYQEEECSPLFCFWGSHSPKFEPLLDLYFSLWHLRKEKQPELLILGNRAFHGKDP
                     GHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKDRTVYLVYFV
                     EKQLMVQEKDKICSLPGGEWIDD"
     gene            4535..6706
                     /locus_tag="ACG84X_002235"
     CDS             4535..6706
                     /locus_tag="ACG84X_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HFP9128068.1"
                     /translation="MTIKWEKWLCGVYSFVILSVGAPIFVVANQLQNSYLLILTIGVL
                     CLIVCCIPKKWVRLLLSLPVMIGCLFLYFPSKTFSLLWILQFFSSVTEEFFHLSQGKL
                     YYLPEKTAFFLIMLLIYLFITLTVDYDYLYAPFLSLMAYFMMLTVFREKDLLYEMIAV
                     VTVLFVYLAARQFFSMRLLSGNTRFQSLTTVLLICFLTISAILPLYLPKVHQSLEETS
                     EPIREYLNDEGLYDTLHEYQLTGSARTGFSENDEQLGGPLYDNGEVVFTANQKGNGYW
                     KIENKNHYTGSGWIEDQDAPIQPIQEFPVDITSYQTVMEDKENITLTLKKQAFLPYPY
                     GNTTLTDFSLASGQTLYYLPESQRFIPVPNESTRSATLQTERLVFTREELKSSQLKAD
                     DLENQQTNLQLPKSLPKRIEDLAVELTKNEATLIRKVEAVEQYLKTSGNFRYSKTDTG
                     HTPKEHDYVDYFLFDSKVGYCDNFSTSMVVLLRTLGIPARWTKGFTNGLRTGTDNQGN
                     EEYSILNSHAHSWPEVYFPGFGWLPFEPTPSFANPMGSQPVAETTETVQPAIEQPNES
                     ENMAETISSERSEVIPSEETTLTPAYKIVLFSLGVCLYVLLFFLLLFRKSLRWTSYLI
                     YLHFFASTNTIAYQKLLNHLETLVPRKPAESLQEYSLRIEQEFKLDLRFIRLTTQYEA
                     EIYGRQADPVNFDKKTYLEITHIIRKTVYKKVLTKGSRFKK"
     gene            complement(6818..8989)
                     /gene="copB"
                     /locus_tag="ACG84X_002236"
     CDS             complement(6818..8989)
                     /gene="copB"
                     /locus_tag="ACG84X_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFP9128069.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHDHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKNQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9009..11195)
                     /locus_tag="ACG84X_002237"
     CDS             complement(9009..11195)
                     /locus_tag="ACG84X_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9128070.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKSKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMSSSLASIAQTIELSRVTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11195..11404)
                     /gene="copZ"
                     /locus_tag="ACG84X_002238"
     CDS             complement(11195..11404)
                     /gene="copZ"
                     /locus_tag="ACG84X_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFP9128071.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(11417..11857)
                     /locus_tag="ACG84X_002239"
     CDS             complement(11417..11857)
                     /locus_tag="ACG84X_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFP9128072.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(11931..12429)
                     /locus_tag="ACG84X_002240"
                     /pseudo
     CDS             complement(11931..12429)
                     /locus_tag="ACG84X_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
BASE COUNT         3520 a         2631 c         2217 g         4125 t
ORIGIN      
        1 gtcaaggaca atcggaatag catacggaaa gaagttctgc accttataaa atttgtcaaa
       61 aaaactgttg ccattccaag tgaaaaaaag atcaatgaat caactagaaa actatataga
      121 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
      181 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
      241 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
      301 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
      361 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
      421 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
      481 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
      541 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
      601 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
      661 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
      721 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
      781 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
      841 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
      901 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
      961 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     1021 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     1081 atcggtgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     1141 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     1201 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     1261 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaaatgc
     1321 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     1381 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     1441 aagccattct tggtaaagta cttttgtcag ctttgatttg ttttcgctct caaattcgct
     1501 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     1561 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     1621 tgctagataa tttttttctt ttattggcaa aatctgctct tctctaaata gcaattcagg
     1681 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     1741 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     1801 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     1861 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     1921 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     1981 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     2041 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgga tgggacagtc
     2101 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     2161 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     2221 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     2281 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     2341 tatttaaata cgcaaatttt cctcattatt tttaatttta ctcaatttaa tcgtattctc
     2401 atttcaaaac gaatgtactt taaaaaaaca taataaaatc actttgcttg taggatgtat
     2461 tcccttccat tacaatgaaa taaatagcaa ttttatgaga aggtgatgtg aaaatggaag
     2521 aaaaaatcga agaatccaaa caaaaaatcg atcagttgat acaagaatta gaaaaagcgg
     2581 tcatcggcaa acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg
     2641 tcttattcga agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag
     2701 ctgtacaggg aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc
     2761 ttggtttttc cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct
     2821 ttaccacgat cttgttggca gatgagatca atcgcacgac tcctcgtact cagtcagcac
     2881 ttttagaagc aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca
     2941 atcatttttt tgtcttagct acgcaaaatc caatcgagta tgaaggaaca tatcctttgc
     3001 cggaagcaca gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg
     3061 acgaactttt gctactttta gataaattcg aaaaagtgtt ggataactta aatgaagtat
     3121 tgaacagtta tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg
     3181 aagtggcatc ttatgccttg cagttagtgt cagcaacaag aagccatgct gccatccagc
     3241 ttggcatcag tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa
     3301 tccatgggag aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt
     3361 cccatcgcct gattttttac gatcgttcat tgaaggaaga cgaaaaaaaa caaatcattc
     3421 atactcttgt tgcacaaatt cctgttcctg tgaggtagat tgaggtagat aatggaaaaa
     3481 atcaaagatt atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt
     3541 gctcttgtat tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta
     3601 tcatggagct tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg
     3661 cagccactcg tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga
     3721 actttttctt tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa
     3781 aaacaagaga ttttgattct tacaaataaa ccgcaagaag tccaattgct ttggcagcca
     3841 aaagaaagag gatgccatga aacattaact gtcattttta cagcctatga tagtctagga
     3901 cttttcagaa aaagtgcaaa aagagagatc tcttttcctg tgactgttct gcctgctttt
     3961 tgtaagattc aagcagaaaa attacagaga gttctggaaa aaaaacagca gctgaacgcg
     4021 taccaaagag gtcttgattt tcgggaacat cgcgcttatc gtccaggtga ttctttcaac
     4081 cgaatcgatt ggaaattgtc tgctcatact caagagtggt tataccgtga atacgattat
     4141 caagaagaag aatgttctcc tcttttttgc ttttggggtt cgcacagtcc aaaatttgaa
     4201 cctctgctag acttgtattt ttctttatgg catttgagaa aagaaaagca gccggaactt
     4261 ctgatattag gcaaccgcgc ctttcatggc aaagaccccg gtcataccta ttttgcttct
     4321 ttggaagctg gcgatgagaa agcttttttc gcacacctaa aaaaatatgc aaaaaaacaa
     4381 atcgtcctct ttgttcctga gaattctcct gaagtctcag aagctattga aacattgtca
     4441 aaagatcgaa cggtttatct tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa
     4501 gacaagatat gttcattgcc aggaggtgaa tggattgacg attaaatggg aaaaatggct
     4561 gtgtggcgtt tactcctttg tgatactaag tgtaggtgct ccgatatttg tagtagctaa
     4621 tcaattgcaa aacagctacc ttcttatcct aactattggt gtcctatgcc ttattgtctg
     4681 ctgtattcct aaaaaatggg tacgtttgct gctttctttg ccagtaatga taggttgttt
     4741 gtttttgtat tttccttcga agacattttc cttattatgg atcttacagt ttttttcgtc
     4801 agtcacagag gaattcttcc atctatccca aggtaaactt tattatttgc cagaaaagac
     4861 agcttttttt ctcataatgt tgctgatcta tttatttatt acattgaccg tggattacga
     4921 ctatttgtac gcaccctttc tttctttgat ggcttacttc atgatgctta ccgtttttcg
     4981 ggaaaaagat ttactgtacg aaatgattgc ggtagtaact gttttgttcg tgtatctggc
     5041 agcaaggcaa tttttctcca tgcggttgtt gtcgggaaac actcgattcc agtcattgac
     5101 tacagttctg cttatttgtt tcttaactat tagcgctatc ttgcctttat atcttccgaa
     5161 agtacaccaa tctctcgagg aaacgagtga accgatccga gaatatctta atgatgaagg
     5221 gctttatgat acactccatg agtatcaatt aaccggaagt gcaagaacag gcttcagtga
     5281 gaatgatgaa cagcttggtg gacctttata tgataatggc gaagttgttt ttacagcgaa
     5341 ccaaaaagga aatggctatt ggaagatcga aaataaaaat cattacaccg gttctggatg
     5401 gatagaagat caggacgcac ccatccaacc aatccaagaa ttccctgttg acatcacgag
     5461 ctaccaaacc gttatggaag acaaagaaaa cattacattg accctaaaaa aacaagcttt
     5521 cttaccttat ccttatggaa atactacctt gactgatttt tcattagcta gtggacaaac
     5581 gctttactat ttgcctgaaa gccagcgatt cattcctgtc ccgaatgaat cgacacgttc
     5641 tgcaacttta caaacagaaa ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt
     5701 aaaagctgat gatttagaaa atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa
     5761 acgtattgag gacttggcgg tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt
     5821 cgaagctgtc gaacagtatt taaaaacaag cggaaatttc cgctattcca aaacggatac
     5881 cggacatact ccgaaagaac acgattatgt ggattatttc ctctttgatt caaaagtcgg
     5941 ctattgtgac aacttttcaa cttctatggt cgtccttctt cgaacacttg gtatcccagc
     6001 tcgctggaca aaaggtttta caaatgggct cagaacaggc acagataatc aagggaatga
     6061 ggaatacagc attctcaata gtcatgctca ttcttggcca gaggtatact ttcctggatt
     6121 tggctggctt ccatttgaac caaccccttc atttgccaat ccaatgggtt cacaaccagt
     6181 tgctgaaaca accgaaaccg tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat
     6241 ggcagaaact atttccagtg agagatctga ggtcattcca tcagaagaaa caacactcac
     6301 accagcttat aaaatcgtct tattcagcct tggggtgtgt ttatacgtct tgttgttctt
     6361 tctattgtta ttcagaaaat ctctgcgctg gacaagttat cttatctatc ttcatttttt
     6421 tgcttctact aatacgattg catatcaaaa acttcttaac catttggaaa cattggtacc
     6481 gcgcaaaccc gcagaatctt tgcaggaata tagcctgcga atagaacaag aattcaagct
     6541 agatctgcgt ttcattcgat taactactca atatgaagca gaaatatatg gacgacaagc
     6601 agatccggta aatttcgata aaaaaaccta tttagaaatt acgcatataa taagaaaaac
     6661 ggtatacaaa aaagttctga caaaagggag ccgcttcaaa aaataagata aaatttctgg
     6721 agaatctact tctggaatgc cgagaaccag ctgcttgagt atcgattatt cgaaaaaaag
     6781 gttgtgacac gttttttgtc acaacctttt ttcattatta tttgattttc aatgtcaaag
     6841 catttagagc tacaactacc gtacttaacg acatcaagac agcaccaact gctggactta
     6901 atatgatacc aattggcgca agaattccgg ctgctagcgg aattgcaaga atattgtaac
     6961 ctgcccccca ccagaggttc tggatcattt tctttcgcgt ttgcttggct agatcaagaa
     7021 aatgcaaaat atcttttgga tcgctgtttg tcaatacgac atccgcagaa tcgattgcga
     7081 tatctgtccc tgcaccgatt gccatcccga ttgaagcacg ggctaaactt ggcgcatcat
     7141 tgatcccatc acccaccatg attacttttt tcccttggtc aaggtatttc tggacaacag
     7201 cttctttatc atctggtaat aaaccgccat aatattcttc gatccctaaa taatctgcta
     7261 ctgcttgggc agcgttttta ttgtcaccag taagcatgac aggagtgatt tttctttctt
     7321 tcaatgttcg gataaattct tttgcttctg tttttactac gtcacctaaa gcaacgattg
     7381 cagctagatg attttctaaa atcaggaagc tgatggtatt tccttgttct tggtaaggtt
     7441 tcaataatgc ttgttctacg tttaatccga gacgctcaac ttctttttca ttaactattt
     7501 tcacttgttg gtttttgact gttgcctcta gcccaactcc tgaaagattt tttagatttt
     7561 cggcttgata aggcttgatt tcatgttctt tcaaataatt cataatacca acagccaatg
     7621 gatgattggc attcgcttcc aatgctccta aatattgaag gatttcattt ttattgaacg
     7681 catcatcaag tacttcgaca cccgttacag taaattttcc ttctgttagt gttcctgttt
     7741 tgtccagcat gatcacatct agatcattgg cttgctccag tgcattgcgg tttttcaaaa
     7801 gtaatccgtt tttagctgct attgatgtag agcgagcaac aactaatggg atagctaaac
     7861 ctagagcatg aggacaggcg atgataaaga ctgttaccat acgttctaat gcattaggaa
     7921 gatctgtcaa gaacaaccag gcgatgaatg ccaggatacc cacaattaat gcgacataaa
     7981 acagccattt tgccactttg tcagataatg actctagctt ggatttttct ccttgtgctt
     8041 ttcgcaccat ttccataacc ttcgctagat aaccattttc accagttcca gttacttcga
     8101 tttcgatcgt tccatcccca ttgatagaac cgccaatcac tttgtcattg gcttgttttt
     8161 tgattcctct tgattcgcca gtcacagctg attcgtcaac aattgtttca cctttcaaga
     8221 ttacaccatc tgttggcatt ttatcaccag accggacgat caaacgatca ccttcgttta
     8281 cttctttcaa tgaaactgtc tcttcttttc catctttcgt caagcgtttt actgattctg
     8341 gcagtaattc tgctagtttt tgtaaagcat tgctggcatt cgacacagca ttcatttcaa
     8401 tccagtgacc tagtagcata ataacgatca aagtagccaa ttcccagaag aaatccatga
     8461 cgtgtgtatg tggattgagc agatttgcga taaacgaata gacactataa atatatgcaa
     8521 ctgtaatccc catcgcgatc agtgtcatca tagcaggact tttttgtttc aattccatct
     8581 tagctccact taaaaatggc tgaccgccat agataaatag tatagttgct aagatcaata
     8641 cgagccaatc agaaccagga aacgttactt gaaatggaaa ttccattccc atcattggtg
     8701 aaaaaagaat gattgggata gctaggataa gcgatagcca aaatttttgt ttgaaatttc
     8761 ccatgtgcat ggaatgatcc atgccgccat gatcgtgatc catgtgcatc gaatggtcca
     8821 tttgtttgct gtttgctata tctccatggt tatgtcccat gtgcatggaa tggtccatct
     8881 ggctatggtc atgtttcatc tccatctgtt tttcatgaga ttctgtactt tctttgttta
     8941 ctacttcttt tttatgttca tgttttttct ccatatcgtt cccattcatt tttactccat
     9001 cccttctctt actttttcat gtgccgattt aagctcaggg agttcaacaa tacactgacg
     9061 gaactaaacg ccatcgctcc tcctgcaatg attggattca aaaagcctag tgcggcaaaa
     9121 ggaataccaa tcgtattata gacaaaagcc cagaaaagat tttgtttgat ttttctcaat
     9181 gtcaccctag acaactcgat tgtttgtgca atggatgcca aactgctact catcagcgtc
     9241 acatcggctg tttccatcgc gatatccgtt ccacttccca ttgccatacc aacatcagct
     9301 aatgctaaag ccggtgcatc attgattcca tcgcctgcca taccgacttt tttgccatct
     9361 ttctgaagtt tttctacgta ggctgcttta tcctctggaa gtacttcagc aaagatatgc
     9421 tttggatcaa taccaacttg tttaccaatc gtttcggctg ccagtttgtt gtctcctgtc
     9481 agcataaaaa catctaatcc tttattctgg agctgcttga ttgcttgttt ggcttctagt
     9541 ttgatttgat cagccacggc aatcaacccg atcacttgct tttcatcagc taaaaacatg
     9601 actgtttttc cctgctgttc taattctaac gcgtgttctt ggtattcatc aaatgatagg
     9661 ttcaattcaa ttaatcgttt acgtgtaccc gcaaaatagc gtactccgtt aatcgtaccg
     9721 ctgattccag cacctgggtg agctgtaaaa tcaatcatat cgtatgttgc tgcttcttgc
     9781 agttttccgt attccacgat tgctttacct agtggatgtt cagaagcttg ttctaaagta
     9841 taaaaaatag ataggacttc tttagaaccg actagatctg taactttggg ctttccttct
     9901 gtaatcgtcc cagttttatc caaaacaatg ctgtctaagt gagcagctgc ttctaatgct
     9961 tctccgcctt taattaaaat tccatttcgt gcaccaacac ccgttcctac cataatagct
    10021 gttggagtcg ctaaacctaa tgcacatgga cacgcaatga ctaatacaga gacactatgg
    10081 atcaatgcga gttgccaatc accagtgatc aaacctgtag ctatgagcgt gataaacgcg
    10141 atgactaata cgatcggaac aaaaatccct gagatccgat ctgcgatttt ttggattggg
    10201 gctttgctcc cttgagcatc ttccaccatt tgaatgattt gcgctaatac tgtctgcttg
    10261 ccgacttgtg tgacttccat gtgtagcaga ccattcgtat tgattgtccc gccaaaaagc
    10321 gtgtcatccg gattcttttc tacaggaaga ttttcaccag taagcatact ttcatctatc
    10381 gcactgcttc ctgaaataat tcgaccatct gctggaatct gctcaccagg acggatgact
    10441 agttgatcac caacgactac ttcttcaatc gctaacgttt cttctttccc gtttcttatc
    10501 acttgggcgg tttttgtttg aagagacatc aattgtttga ttgcattacc tgttttcgtt
    10561 tttgctgtat gttccaaata tttgccgagc aaaatcagcg tgatgatcat actgctgctt
    10621 tcaaaataaa gatcttgggg gtgtccacgg aaaaatccgt tgtaaatgct caatgcaaag
    10681 gcagccgatg ttccaattgc taccaataca tccatatttg gtgctttcga cttgattgca
    10741 tggtacgcac ctttataaaa acgagcaccg acataaaatt ggacaggagc agacagcact
    10801 aactggacga ttggaaaatg aaaaaagtga acaatcgccg catggcttcc taacatcata
    10861 gcaatcattg acaacatcaa cggcaaagtc aaaaccgtac tcaatataag atcgaatagc
    10921 atttttttca aatacgcttg cttttcttct gcaatttttt gtttgtgggc ttcatcgtac
    10981 aaaattgcac catagccgat gttttctacg ctttggatta atttttcagt ggtcgtccct
    11041 tcatatttga cacttgcttt ttcagtggcc aagttgactg tggcattgac cacaccaggt
    11101 tgtccgttca gctctttttc gatcctagca gaacaatttg cacaagtcat acctgtaatg
    11161 acgaacgtat ccattttggt ttctgctgtt gccatcaaat cacctctgct ttataaccca
    11221 atccattgat tgcttgacaa atcttttcgg attgaacttt tgtttcatca aacttgaccg
    11281 taccgtttgc ttttttcaaa tttactttca ctttttgcac gccgtcaagt gcgcttactg
    11341 tttcttctac tcttgctgca caatgattgc agctcatacc ttcgattgaa aattgttgtt
    11401 tcattttttc ttcctcctat tgatgttgtt tacattcaca ttgacctggg atacagttac
    11461 attcgatcgt atctactggt tgcttttgtt ccagttgttt caaaatctca ttgatatctt
    11521 cttgagtcaa agtggcttct tctactagat ccgcaatcgt ctctccaatc ctttttgcac
    11581 agatatggga aaaaagattt tccgtcgcac tgcgaactgt ttccatctcc gagacagctg
    11641 gatgataaat gaattttttt ccttcttgtt ctgtccagat cacttctttt tttaccaaac
    11701 gacccagcaa agttttgatc gttgctggtt tccaatccat cgaatcagct aagatctgcg
    11761 tgatttcttg ggctgtcgtc tgtccaagtg tccaaataac acgcatgatc tcccactctg
    11821 aatcactaat ctttactggc gttttgactt tttccattta tttcacacct ttcgtttaca
    11881 aatgtaatca ttaacttatg aatacagatt acacttgtaa acaaaaactg tcaattattt
    11941 ttgctctcta ttttcaattt agttaaaaat tcttgtttct ctcgtcttgt tttaaggatg
    12001 atcagtttat ttcttgcatt agctacttgg atcagctgct gtatttttgg ttcattgttt
    12061 ccttcaaaat gccagataaa agataaaaat tctaagtatt tcctgtttag tttctccgaa
    12121 aatgattcag gcatatctgg ccgagatttt ttgtttatct ttctttttag agaacgccaa
    12181 actactcggt agatggcgag ataacgcggc actttaagcc aaatgatctt atctgcttct
    12241 ttaatccttt cctctaacgt agaagtataa tttccttcaa cgatccatga cggattagat
    12301 accataaacg attgctgttc ttgcaaaaac cacttttttg cctgaatgcg gaaagccggt
    12361 gatttctttg atcttccttg cgagggacga ttttcccgac ccactttgtc caatcacgat
    12421 gatcttcatt cttctccctc acttctcttt ggaatttggt tcgatcatac cacttataac
    12481 gccgcaaaaa aac
//
LOCUS       DAZKCH010000077        12480 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000077 DAZKCH010000000
VERSION     DAZKCH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.078"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1233)
                     /locus_tag="ACG84X_002241"
     CDS             complement(<1..1233)
                     /locus_tag="ACG84X_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFP9128073.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMI"
     gene            complement(1330..1830)
                     /locus_tag="ACG84X_002242"
     CDS             complement(1330..1830)
                     /locus_tag="ACG84X_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFP9128074.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            complement(1843..2064)
                     /locus_tag="ACG84X_002243"
     CDS             complement(1843..2064)
                     /locus_tag="ACG84X_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128075.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            complement(2069..2206)
                     /locus_tag="ACG84X_002244"
     CDS             complement(2069..2206)
                     /locus_tag="ACG84X_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFP9128076.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
     gene            complement(2203..3387)
                     /gene="mobT"
                     /locus_tag="ACG84X_002245"
     CDS             complement(2203..3387)
                     /gene="mobT"
                     /locus_tag="ACG84X_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFP9128077.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(3643..3897)
                     /locus_tag="ACG84X_002246"
     CDS             complement(3643..3897)
                     /locus_tag="ACG84X_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128078.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            complement(3922..5064)
                     /locus_tag="ACG84X_002247"
     CDS             complement(3922..5064)
                     /locus_tag="ACG84X_002247"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFP9128079.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            complement(5124..6476)
                     /locus_tag="ACG84X_002248"
     CDS             complement(5124..6476)
                     /locus_tag="ACG84X_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFP9128080.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFWVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            complement(6547..6891)
                     /locus_tag="ACG84X_002249"
     CDS             complement(6547..6891)
                     /locus_tag="ACG84X_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFP9128081.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            complement(6901..7275)
                     /locus_tag="ACG84X_002250"
     CDS             complement(6901..7275)
                     /locus_tag="ACG84X_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFP9128082.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            complement(7288..7602)
                     /locus_tag="ACG84X_002251"
     CDS             complement(7288..7602)
                     /locus_tag="ACG84X_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFP9128083.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(7716..10943)
                     /gene="fss3"
                     /locus_tag="ACG84X_002252"
     CDS             complement(7716..10943)
                     /gene="fss3"
                     /locus_tag="ACG84X_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFP9128084.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITDAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(11022..11684)
                     /locus_tag="ACG84X_002253"
     CDS             complement(11022..11684)
                     /locus_tag="ACG84X_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128085.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            12301..>12480
                     /locus_tag="ACG84X_002254"
     CDS             12301..>12480
                     /locus_tag="ACG84X_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128086.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENNQ
                     PVIAKKETVLSEGKIK"
BASE COUNT         3507 a         2794 c         2049 g         4130 t
ORIGIN      
        1 aatcattctc aaccgttctg tttctttttc aaccagacca ttctcttgtg taaattcata
       61 aatagaatgt ctatcctgtg ttcttattat ttgatatttt gtccccttat agaaaatatt
      121 cagtttcaca attgtatcct tcaaaaatat tccagagcca ttatgttcaa tttgtgcaaa
      181 gttctgataa tcactttgta tttcagaaaa ttgatcaagt tctgcttcct ttccaaggac
      241 atagaccaag aatcttgtaa tacaagattt gcctgttcct cttcctccaa taattgaagt
      301 taaattatcg ctgaattcga ctacaacttc ttttgtgcta agagtggtcc cagaaaagct
      361 taatttttcc aataaaactt cattttcatt aatggagaaa ttagaaaaat cagaatgaac
      421 tcgagtttcg cctagcatta aagcatcgcg aagtgatccc aagtcaggtt cgtccttcat
      481 ttttatatag gaatatcttg tgcctattcc ccaaagtcca tgttttgaat ttcctttcga
      541 gtgtgggtta tcagaaaagc taagaaatgt catattattt ttttctgcct caacaactga
      601 tttataccaa gattccaaag tatcttttcc aactctacca tcatatctgg cattcacact
      661 atcatagata gtgtcacgct tagatgaggg aatcatttgt gagcgatttt caaaaaattc
      721 tttttgaacc gtctgtactg catatatatt ttctgattca aatatctttc ctagatttcc
      781 aaattttgct gaagaaattc cattaaactc atctatatgt gcaggaataa cgagcaagcc
      841 ctcgtgctca gcaaaatcaa taacttctaa aactgatttc attgagcaag ctgcagcgct
      901 ggcccaatcc tctcttttta tacccatctt ggttaagaaa tcagagatat catttgtaca
      961 tgcactttta tcaaatagga ctagtaaatg agttccattt tctccacacg ttaattccac
     1021 tccaggaaaa aaatctaagc cattttcgat agccactttc ttatattcat caatattttc
     1081 ccctgtattg tgatcagtta atgcaacaca atcgagtcct ttgtttaaac attcttctac
     1141 ccattcctta gcagtaacct ttttatcctg aaagcactga ctcgcagttg aatgaatatg
     1201 aagatcacat ttgtaccact tattgccaac cattagtaac acccctatca acaaatattt
     1261 tctatttcag tatatcaaat agaaaagtaa aagtacgata gaaatttctg gtcaattcta
     1321 acaaatgatt tacattagtt caaaaacccc tcgactcgta accaaataat tcccgccaat
     1381 ctccaagtct cgaccacacg catcaaaatc aatatacgtc ttcaagtgtt ctggtacttc
     1441 gcctaaatca ccagcttcta caatcaagta atacgctaca tcactcatgt cattacaatc
     1501 gggataatag atgatatcat ccacatgctc taccatttcc tcgaaagaat tgaagaaggc
     1561 atgttgaatc tctgaagcga cctcaccaat tggcgttcct ttaagctctt ccgctaaacc
     1621 acacaaccga ttaatttcct caattggtgt atactcatca atctcaaaag gcagttcata
     1681 atcatgaatt gcgtactctt catattcgtc atttaatcca atccgttctt tcacttcatc
     1741 aaaatcgacg ggtggggtaa accatgcccc caccaactca ccttcattgt attttccaag
     1801 gttcgcaata taaacacgta tctgttccat tgtgattccc cctcaggcac cgacaattcg
     1861 gttaaacaaa ttgagtaaga catccttcac accagaagca ttaaagacca gacctaccgc
     1921 aatcaaagca atcaccaaga agccaatcag tttggaaaac tcgcgtttaa atcctaaaaa
     1981 caaaccaatg accacaatcg ctagtaagac taaagattga gcattggtta aaaaccattg
     2041 atacaaattt tgaccgaaat tcatttcatc actttccttt cttttccatt gctcggtccg
     2101 ccgctgcact tgcatgcatc aagcacatca cagtaacacc aagcatactg ccaccaaaca
     2161 ccaataaaat atctttcaca atttccatca cgattcctct tttcatataa tcaaattttc
     2221 aattgccata ctttgttgct ccaaaatctt tttgtgccgg tctgatagtc gagtattatt
     2281 taccatatcc tgaatgtacg ttgtctgatt caaccgatcc aactccttgg ccatcttcca
     2341 cgtaggggcg acttgtcgtc caagccagtt caacgttcgt tcaatggtat aaggcttcgg
     2401 ttcagaagtt aattgaattt ccttctgatt ccgtccaatg aagcgccccc attgttcatt
     2461 caagggccag ttagttcgcc ttttgccttc caccttatcc gcaaatcgca agtaccggtt
     2521 aataatggaa aatgtggtac tttcaatact gcgacctttt aacaaatctt gaattgcatg
     2581 ataagctcga tcatttttca gtcggatttc aaaacgattt ttcgtttcgg tctggtctaa
     2641 aggaatccct aacttgatat attgctcata gtctttttcg tacaaacaga aatagacctc
     2701 actcttaaga ctgccaatat acaaagtatt gcccatacca tctttatcat caggtttcaa
     2761 cagttccccg gaacgatagc ttttgaaggt acgaaacaag gagatacatt cttccttctg
     2821 acattttttc gttaaatcag gaatatctaa caggccaact cgatcattga ttgccaggtc
     2881 taagcgtttc atcacgccac cggcttttag acaatcttcg aaaaagtcat accagctacg
     2941 cttttgggcg agtaaaaaag tttcaaactg ccgacaacca cgacccttta attctaaaag
     3001 gacgccttta tcttcttcat gtgacaacat caccacaata tctcccataa catattgttc
     3061 ttgataggag taaaaggcgt aatcttcgtg gagcatataa tcaaatttca aatggagaat
     3121 ctcttgaatg attttcctcg catccgttgt gggaaagcga atccttacat agtcaaacag
     3181 taacgttaaa ggtaactcgg gattgaaact ttccagttgg tcaaaaattt tcctcatggt
     3241 ttttgtcgat gcggttacgc caccattttc tatctgattt aagtacgggc gactaagtcc
     3301 acaagtcgta gctaatttat tttgtgaaac gccatattca ttacgccggt cttttaatag
     3361 ccgataatct aaattccttt gtgccaagtt ctcacctcca aatttaaggt gttaactttt
     3421 tcaaatcagt taacatctac acaaattgct tattatcctt gataggacag ccattcctta
     3481 tcgttgcttg cttatttttt gtgtttttgt acccccctgt tagatacggg gggtgagaca
     3541 tcatggccgg ctaacgccgt ccataaacag gcacagcacc acggaggatt tctgcttcgc
     3601 aaatcccccg cggtcagtgc ctatcagtgg tttatttggc cgttactccg cggtaatacc
     3661 ctcaatttcc aactctgctt ttatctcaaa caagtattgg cggatatcag gttctttagc
     3721 aaagtccgca attcgttcca attcactgat gacttgattc agctccattc gagcatccgt
     3781 ttcctcatca attacatacg gatcatcagg gactttcacc ccgtttttgc gaatatcaaa
     3841 attgagccgg tacagttctt cttccaattc cggatctgac tgaatcttgc caatcaccca
     3901 gtagattccc caatcaactc atcataaatc atctgttttt acctccttta atcttctagc
     3961 aatatcaaaa atgaccggaa ctgttacaga atttccagcc tgcttataca actgactatc
     4021 tgaattgact tgagaagctc gatcaaaagc ccagtccgga aagccctgaa gccgccagca
     4081 ctccctaggt gttaactttc gaatttgata ctgatccgtg acgactgctt gttggtctcc
     4141 tgttaataag gtatgcacac tttgttttcc cagacggcct cgacgacttg tggaattagg
     4201 aaaagccagg ttcacactgt tccctggctt cacctcttga tattctgttt cgtttttccg
     4261 aagcatgatc ttcgttccgc cttgtttcgt tgacaaagta ggcgctgttc cagttatctc
     4321 ataaacccga ttgccttgtt caaaatttcc cagtaacata cccgctacag aaattccatc
     4381 atctaccggc aatgcgattt tgattccttc atcaccggtc aaggtaggcg ctacgtcatc
     4441 tgacccatag acttgtcccc ccattcctcg attggaaggg ttgatattta ataagtttct
     4501 gatgttttga tcagatgttg gagacgatcc aatgatagga aatacttgtt cggtacatgc
     4561 gtctcgagaa tgtccgataa ggaagatccg ctcacggttt tggggaacgt aggcctttga
     4621 gttaagcact tgccattcca catcataccc caatccatcc agcgttcgga ggatcgtctc
     4681 gaacgtagcc cctccttcgt gattgagtaa tccccggacg ttctcaagga ataaaaactt
     4741 aggttggaga atagcggcga accgagcgat ttcaaagaat aaagtacctc gagtatcgga
     4801 aaatccttgc cgctttcccg caattgaaaa agcttggcac ggaaatccac cgcaaaggat
     4861 atccactggt ccgagagatt gaataaactc gtctgataca cttgtgatgt catgcatttc
     4921 cacctcctta cttgtatcat ggattgcctt ataactctgg cgagcaaaat catcaatttc
     4981 acaaaagccg atacactggt gacccgcttg ttccatacct aagcaaaagc caccaatccc
     5041 agcgaataaa tctaaaaatg tcataaatca cctcgtaaaa aaagcccagg attcttgaca
     5101 ctcctaggct acatactatt attttatcct tccgtattaa cgtttaatcc accaatgtcg
     5161 ctaatttccc ttaagaaatc atatcctttt ggtacaagtg gcgtataaaa ctcactaatc
     5221 acactccctc ccgtatctac atagcctcga cctttgatac gcttcataaa gaatttttta
     5281 tcaacctcgc caaacatcat ggaatatccc agttcactca tacgacccaa agccacccag
     5341 aaattaaatt gatcgcgaat cccgtctcct aaatatttcg catccggtct ttgacaagct
     5401 agaatcagaa agaaaccaga ttgacgacct aacatcacga tttgtttgag cttattcaaa
     5461 atcaccgcac tttccttcgt cgttaacatt tccatataaa ccacgtattc atcaaagatt
     5521 aaaaagtttg gtggaagtcc aagaaacgca taattctctc ctgttttgta gttgggcatt
     5581 tctttcattg ccttgctacg agtcatcatg cgctcataga aatcttccac acaagcagaa
     5641 atttcctcct tttgggaata gacatgaggc attaccgtac ctaaatcggc taagtccgca
     5701 tttttgggat caagaacaaa aagctcggca tcagatttta ataaagcctc gatgatagtg
     5761 agtaaaaagt aagtcttccc accacctgtg ccgccagcga ttaacatatg aggtaaagaa
     5821 tcataagccc atacttgatt tttcatcaat cgcaaagccc cactttctgc cactacttcg
     5881 tctatcccaa ttcgattggc aattatatca tacagtaaag tgtactccac ataggagtct
     5941 ttgagttcct tttctactag ttcacaatat agaccacttt ctaacttctt ttccagcttt
     6001 aaaagctgat cttgatattt tcccagtgaa atttgaacgc gaatagaaag taaaccatcc
     6061 ttcatacggt aatagatttt ggggaagtaa ctgattgtct ctttggttcg actactattg
     6121 aggtctttga aaaatccttc actctgagtt tgttttactt cgtaccaatg attttctaga
     6181 atcatccggg ctagcttttg tcgatgccac aaactgcgcc aatgatcctg aaaaaagtgt
     6241 atataaagca acatcgtgct tcctgaaaga acgagacttc ctagcaaata gattaaatct
     6301 tttatagaac gaacgatttc tatagtagaa agtgatagct tagaaatatc aaattgtcta
     6361 agctcttgaa aataaaagac gctcatccaa ccgatgaaca gagcgagtag ccagccaaga
     6421 acaaagtgat aaaccaagtg ctgatctcct gcccgtatac gatgcccttt gtacattttt
     6481 atggtttcca cctccaatcg aaaaaagctt cataggattt cattgatcca atttcaagca
     6541 gttatgctag tcatttactg ctatagggag ttgtttcgtt tccactagtt gctttaaaaa
     6601 aacttcaatg gcatccggca tttccacacc aatttcttcc aatacggttt cggcttctcg
     6661 acatagactt tcatttactt cgataaccat aaagaaggac tcttcttccc ctaaccaatt
     6721 cagtacatca aaatcttctt cggcatcgtt acctacttcc agtaaccctt gatgcataat
     6781 cagaaacatt ttttcatcat aggttaatgc tttagtgagt tgttcctccg ttagctcacc
     6841 ttttccatat tgatcgagac aatctaaaat atgttcaaca ttaatttcca tacgcttcac
     6901 ctatttcttt ccttcatttt ggtttgtaga atttccctga tctggttgtc gtttcaagac
     6961 taaatcatcg gccttaatga accaattgac agtagttcct tctcggaaaa cataattggc
     7021 gaccgtatcc atgattggat tgaccaactc tacctctgcg tcataggcaa actcgcgtaa
     7081 gggtacattt gctgggatac taacttggat cattcgacct tgcgcagagg atttcaaatt
     7141 ataagtccgt tcttttacct cgttactaac cgttccatcc tcattttgct tccgtacttc
     7201 tcggcgtaat gcggaaaatc gtaatttccc aaacgttagt cctgaatcta caacaatacc
     7261 ttctgttaat ctcatcttct tttcctccta tgctttcact aaatcatcga catacaacac
     7321 gtagtcggta aacccacgat tctcaatctc atagcctttg gcaaccaaat ggggattcac
     7381 ggcttttagt ggttgatctt gatcaaaatc cttttcgccg gcttccgcag ctaccaccac
     7441 ttcaatatca tcggctcgtt gcttactgga atacaaatga taactacgac caattactgt
     7501 agtattccgc ccatatcctt cagttaaaac ttcgccttcg ccggcatacc ttatctttcc
     7561 aaaggtttcg gccatatctg gcacaacaaa tttcaattcc atcttctttt cctcttttca
     7621 tttttagttt tggatacaaa aatagcgcga ccactttttt taggaggcgg tcgcgcacgt
     7681 tggtttttcc tatttagttg tttcatcaca tcaccttagt ttcggcgatt ccagaaataa
     7741 tacccagcag tcgcaaagat caaggtaaac ccaataaaca gcagaacatt agaatttttc
     7801 tcccctgttt gtgggaatgt ctttactgta ggactagatt cttgagagtc acttggaaca
     7861 gttggtattt ccggttgttc tggtgcactt ggtgttgtcg gaactttttt aggtgttaaa
     7921 gtttgagttt tttcttttag atcctcattg tgtttcccat tgatgtttcc gtctttgcca
     7981 tagttaattt ctttgaaggt aaaacttgta ccttctggat atttacttgt gtccactttt
     8041 tccgcaagta cggttttagt gaattctttg tcattcactt cataatcaat tttgccagat
     8101 ttccaaattt ctttggtcgt attatccgga agtaatgcat acagaattgt ttcaaaagct
     8161 tcttttgagc catccagtac atcatgggta atcgacacat catcgaacat atccaccaca
     8221 tccccatgag taaaggtttg cgaaccatct tctaggtggg cttttgtttg gatggaaaca
     8281 tggcgttcca ccgtacaatt gacagtttgg gcttgattgt tcaagctagc atctttcgct
     8341 actggatcat cacctgcttc atagggtttc ttgttttcat acacatagtt gaataagacg
     8401 atggttttat ccaaaacttg ttctgcggtt aatttatgca aaattttcca agttcctgtt
     8461 ttctctttat tcgccaacgt tgcggttgtt tcggcaatta ccactggttt ggctttttca
     8521 tctttttctt gggcagcttt tgtcgcttcc acatcaatgg cttgcgctac cacataccag
     8581 tcttctttga tttcatgcaa gttatagctc aatttatcaa ctagctcggt agaatcaagg
     8641 tctgtcaatt ctttgcctcc gtctttccaa gtcccaagag aagttaagct atcttcttct
     8701 tcaggtaaat catagagcat caaacgattc aagctaacag aaaatgcttt attcgtcagt
     8761 ttctcgtaag gaacggtcac cgttttaatt ggttgttttt gtcctttttc ggtaatcgta
     8821 aaaatgtatt cactcttagt gtaatccgct ttattttctt taaaagtaga acggatttct
     8881 aatggcgtaa ttttttgaaa tccttctgga gcctctactt cttcaagtaa ataatcccca
     8941 taaggaagat tttcaaactt gccatagcca tcaaaaccta gttgctcgtt ataagctgta
     9001 attgcttcat cttcggcatc tgtaatctca ctggttcctt ccaatggcga tactttaaag
     9061 gtcagatcat tgaagccagt ttcggcagtc ccagcagctg atccagcaaa tttaaagaaa
     9121 tcaaagccaa agcgaatgac ttgttctttt gccgtaacat ctcgggtaat cacggcattt
     9181 ttttcgttat catccacctt tttgatggaa acagggtact ttgtttcatc caaggtatat
     9241 ccttcaggtg ctttggtttc ttgccagtaa tactcattaa tcgctaagtg tttaacagca
     9301 acttgattct tttcatctaa agtcaaagtc accgtttcat cagaagcttt cgttcccttc
     9361 actaactctg gtttaaaagc ctcactccat ttgaccgctt gaccatcttt tgcagtaaag
     9421 agagtatatt cagctccttt aaactcagct ttaccttgag tttcattacc ggtatctttg
     9481 tcttcttttg tcaaagtggt ttcaccagtg atttcttggt tttgcccttt tacgttactg
     9541 gtaacaagag ccacggtttg attgacatag ttcaattcga cttttactgg tttaaaggta
     9601 ttcacaaagc cattactagc tttggtttcg gtcacataat aggttcccaa ttccaacgca
     9661 ttggcaatct cttttggtgt ttccgcatga cctttttcat ccgtggtcat ttcttggaca
     9721 atttcaccgg ttggactgtc tttgcgaatg gcaaacgtat ttccggctaa tgagtatttg
     9781 tcgttccaaa gatcagttcc tgtttccacc cccattttat tcaaaatgat ttgacctttt
     9841 tcgcgagtat tttttgaagt cacagaaata gtctcaccag atttaatggt tgcggtgatt
     9901 ggtgtagtgt caatcgtata aggagctggc actgattttt cagtaatggt tactttcgcg
     9961 ccatgaggaa tctcatccaa tgtcgcaatg ccttctttat cggtggtcac gtcttttgca
    10021 ggtaatgttt ttccaaagtc taaatggaaa acggttcccg gtacaacatt tcctgtttct
    10081 ttatcgactt ttttaatctt caaagaaccc tcagtttcca catcaatttt gattgtgtag
    10141 gtattgggct tatcaattgc ccccgccatc aaagtttgtt gaccagccat tttataagct
    10201 accggtgttc ctgtattagc tgacttcttt agggttaatt caccactctc ttttgaattg
    10261 gcatttggag taatcactag ttgattgccg ttcacacgat aatcaatatt tgcgatattc
    10321 tcgacaactt catcaaactc cgataaattc aagccgttcg tatctgtcac agtagtcgat
    10381 tgacctaaca cggttttcac tgtggagtta tggaagcttg gtttcttttg ataatccgca
    10441 atggcttgat tgatttttga ctcaatggct gcgatattta ctgcactacc atcagaacgt
    10501 ttaattgagt gaagcgtgta gccattaact tcttgccaaa tcatcttctg ggccacaata
    10561 tgtgtatcca catccgtacc agcttccttc cataaaacgg aaactaattt cgctttctcc
    10621 gacatatcag gcaatggatt tttctcataa ccaggagtga actcattgta aatcggcacc
    10681 cctggctcaa tacagaaaat atcttgcttc acaccattgt aaactgcata gtgcggaacg
    10741 gtaacttctg acatgggacg accatcgcta aatgtacctt cgacagcata ctggtgagcc
    10801 aaatccaatt ccacagttac cgtttgtgga tgagtaattt catcagcaaa ggcaatcgtt
    10861 gggccaagcg atccaccaat tgtttggcat aatagactca gtgttgcgag caaacgccaa
    10921 ttcttaaatc ttggcttttt cataaaataa atctcctttc gtttttgggt aataaaaaag
    10981 acgtccaaat tttaattttg aacgtctgat ttagagtgat actatttagt tttctttgtc
    11041 ttggataggt tgtttctctg cttataaatt ttgattcttc gataatcaaa tccaatctct
    11101 gccatcaatt cctcccaatt tttgttcgtt cttttcataa ttgtatcaac tgatggtagt
    11161 tttggggatt gaactagttt tcgaaacttt gtcattgata aatcatcctg tagttttaat
    11221 cggattattt cattttttag ttctaacagc agttcgaaat cagtaaatcg agatccatca
    11281 tttttttctt taaaaagtgg acgtatatct cctaacatct ttttaatggt actaagtgaa
    11341 ggaatattct tccctactga tttttgttcg tacattcgtt gagaggttat cttctcgcac
    11401 ttaataaagg cttctactat ttccaataat tcttgttctg acattctagc ccattttcca
    11461 tacccagtat tttctcgtcc tatactaatc aataaattct cccatgatcc atattttttg
    11521 ttaatgaacc acatacttgg tgcagaattt ggattttctg atagcttttt ctggtattga
    11581 cggctagatg taattccgtg tttttcgatg aattcattaa ttgttaaaat cagttttaac
    11641 tcactttgat ttttccaaat gatacgtcca tcattttgct tcacgataaa aactcctaat
    11701 agttatttag atagaagcct atcacatcaa ctttttagta gaaaagtaca tgttttgtct
    11761 tttttgctaa tagctgaccc tttgagaaac ttgggttcaa aagttgctaa attcggtaaa
    11821 tgttttggta tttttcgtat tatatttgtc gtcaagctga ctactaaatt ttgccctatt
    11881 ttgacgacac tgatagtcaa tgtcggacaa tctaggacaa tttttaaggg aatatgattg
    11941 aaaaatggtc caaaacagcc aaaaatggct taaaactgtg atagagaaaa aagaaaaagc
    12001 ccttgatata caaggacttt tcacaaattt cagatttcca aggaagtttt ccgtgtttat
    12061 cttctgattt ctttgatacg agcagctttt ccgtgtaatg cacgtaaaca aaaccactat
    12121 attctattat gtatctaata ccctcaaaac agctataaat caacaatacc gacatataat
    12181 aaacactatg ttcaatctga gatatatcaa aggtaaacgt atttttgccc cctttttgcc
    12241 cctcaaatat cgctttacaa cgagaacgta agttcgtata atcgttttga ggtgattttt
    12301 atgatggaag actttattag aaaaaatatc agtgatgaat atgcagactt ttatgagcaa
    12361 agcagcaaaa aagataaatt ccagatggat gtttcaatct tagctatatt agctttttcc
    12421 gaaaataacc aacctgtaat tgcgaaaaaa gaaacagtat tatctgaagg caaaataaaa
//
LOCUS       DAZKCH010000078        12335 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000078 DAZKCH010000000
VERSION     DAZKCH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.079"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..154
                     /locus_tag="ACG84X_002255"
     CDS             <1..154
                     /locus_tag="ACG84X_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFP9128087.1"
                     /translation="SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL
                     RYSLGY"
     gene            complement(208..486)
                     /locus_tag="ACG84X_002256"
     CDS             complement(208..486)
                     /locus_tag="ACG84X_002256"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128088.1"
                     /translation="MENKVGYVRYNFFSSTPIMKDFASFNEALAVELSHDRERIHYEK
                     HVIINDLWNTEKTDLLALPDTDYPVFKEIEVKANKYNEIKQNKITNLS"
     gene            complement(601..1218)
                     /locus_tag="ACG84X_002257"
     CDS             complement(601..1218)
                     /locus_tag="ACG84X_002257"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128089.1"
                     /translation="MLTMTDINTIRNLRNNHDKSINHIAKELDVNWRTAKKYADDDLL
                     PQPKARKKTGMMYTEKWGGIVSLWLSEDAKLPNKKRRTAEAMTTALKADGFPGSYRTV
                     CVFIQDWKATHYLETLEDQGFERLEHPPAEAQLDFGTMEVCHDGAFKDVKVLVMTFPF
                     SNAGFAVVLPAENQECLLEGMKELFSQSGGVPRKIRIDNMSTAVT"
     gene            complement(1613..2437)
                     /locus_tag="ACG84X_002258"
     CDS             complement(1613..2437)
                     /locus_tag="ACG84X_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFP9128090.1"
                     /translation="MEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAGANKKLV
                     YNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLKILTTFL
                     YVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKFVYDDFS
                     DELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGIPYINNL
                     GLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQHLEIS"
     gene            2780..3196
                     /locus_tag="ACG84X_002259"
     CDS             2780..3196
                     /locus_tag="ACG84X_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9128091.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3193..3663
                     /locus_tag="ACG84X_002260"
     CDS             3193..3663
                     /locus_tag="ACG84X_002260"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9128092.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3677..4450
                     /locus_tag="ACG84X_002261"
     CDS             3677..4450
                     /locus_tag="ACG84X_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFP9128093.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4464..5276
                     /locus_tag="ACG84X_002262"
     CDS             4464..5276
                     /locus_tag="ACG84X_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9128094.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5330..6295
                     /locus_tag="ACG84X_002263"
     CDS             5330..6295
                     /locus_tag="ACG84X_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9128095.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6431..9154
                     /locus_tag="ACG84X_002264"
     CDS             6431..9154
                     /locus_tag="ACG84X_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9128096.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9167..9799
                     /locus_tag="ACG84X_002265"
     CDS             9167..9799
                     /locus_tag="ACG84X_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9128097.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10007..10231
                     /locus_tag="ACG84X_002266"
     CDS             10007..10231
                     /locus_tag="ACG84X_002266"
                     /inference="COORDINATES: protein motif:HMM:NF015692.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HFP9128098.1"
                     /translation="MQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEVI
                     PENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10333..10566
                     /gene="relB"
                     /locus_tag="ACG84X_002267"
     CDS             10333..10566
                     /gene="relB"
                     /locus_tag="ACG84X_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFP9128099.1"
                     /translation="MSQSTITFRIPDDEKELVLEYAKAHNSSLTELYRNAVLDKIEDE
                     IDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10556..10825
                     /locus_tag="ACG84X_002268"
     CDS             10556..10825
                     /locus_tag="ACG84X_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFP9128100.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(11004..12305)
                     /locus_tag="ACG84X_002269"
     CDS             complement(11004..12305)
                     /locus_tag="ACG84X_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9128101.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         4029 a         1998 c         2422 g         3886 t
ORIGIN      
        1 ttccttagaa aaattaggtt gtcaaaattt caactcacgt tctgttaaag ggctagagag
       61 tagatttgaa agcatattac tggcttacag tgttctatta agtcgagcac aacgacgttt
      121 tgaaggaact ttgagatatt ctttaggata ttaaaattaa ctagcaccac gggtaaaata
      181 aatagttttt ctatcaagta tattgaacta cgataaattt gttattttgt tttgtttaat
      241 ttcgttgtac ttattggctt tgacttcgat ttctttaaat actgggtaat cggtgtccgg
      301 caaagctagc aaatctgttt tttctgtgtt ccatagatca ttgataatga catgtttttc
      361 gtaatggatt cgctctcgat cgtgtgacag ctccaccgct aatgcctcgt tgaaactggc
      421 gaaatccttc ataatcggtg tagatgaaaa gaagttgtac cgtacatagc cgactttgtt
      481 ttccatacta cctttctcgt ttccgctacg tggattgcac acctgtgtct caaaaccata
      541 gtgcatagaa aatcggagga aaccgtcagt cagcaccgct tgttcagtct ttgtttttgt
      601 ctaagtaacg gccgttgaca tattatcaat ccgtattttc cgaggaacgc cacctgattg
      661 gctgaagagt tctttcatgc cttccaacaa acattcttga ttctcggcgg ggagtacaac
      721 ggcgaatcct gcattactaa aagggaaagt catcactaat accttcacat ctttaaacgc
      781 tccatcgtga caaacttcca tcgtaccaaa atcaagttgc gcttctgctg gcgggtgttc
      841 aagacgctca aagccttggt cttccagtgt ttccaagtag tgtgtcgctt tccaatcttg
      901 aatgaataca cagactgttc ggtaggatcc tggaaagcca tcggctttta aagcagtagt
      961 cattgcttca gcagtcctac gctttttatt tggcagctta gcatcttctg aaagccatag
     1021 ggaaacgatg cctccccact tttctgtata catcatacca gtctttttgc gtgctttagg
     1081 ttgcggcagc aaatcatcat ctgcatattt tttagccgtg cgccaattta catctagctc
     1141 ctttgcaata tgattaatgg atttatcatg attatttcgt aaatttctga tagtattaat
     1201 atcggtcatt gtgagcatac ctttcttacc tccagttaca gtgtcgagac tataacttta
     1261 gaggagtttc aggttgcccg caatggcttt ttatcttaac ttaatcgatt tgcggagttg
     1321 tgtagttttt cgttgcactt gtatgtactt ttattctgcc ataaacagct taatgaatgt
     1381 ccacttgaaa aagtgaataa acgaaataga tgactcgatt taataaggaa gtaaacccac
     1441 acagaaatat aggtgatttt ccttgaatga ccaagatatt gaaagttagt gaaaaaacac
     1501 aaaaaggtag ccctattcac agaaggtctg ccttttgtgt tatcgccagc aaacattaga
     1561 gggggtattt catatagctt ttgtcctctc gacagtccta tcagtttctc ttttaactta
     1621 tctctaagtg ctgtccagtt ttaatagctt ctagcttgtt tcctaactgt gtttttaata
     1681 tgttgaaggc ttttgaacct gtgcagtggc aagtaaggat tttttctact cgtgagtcat
     1741 tcaatttatt tccaattttc attacctctt gctcaggtag acctaaatta tttatataag
     1801 gtatgccaat catatggaag ccaccaatta ggtattttat gggtttagtc ggaaatgttt
     1861 caagagcaat ttccatcata tcgataatgc catgatgact acagccagta aagacaatca
     1921 gaccgtcttc ttgctcaatt acgaccaata attcatctga aaaatcatca taaacaaatt
     1981 tatcatccat ctttttgtat aaattcttgg tggtcgagtt tgctttgcct agggggatga
     2041 tatggaagct cggagcaagt tctgttttcg tttttattgt atgtaaattc tcatgcattt
     2101 taaggatttc atttttagga ataccaacat acagaaacgt ggttaaaatc tttaaataat
     2161 ggggtaaagt tacaccttca gctgtataaa taggggcgtt tcctgatttt aaatatctta
     2221 acccgccggt gtggtcagaa tgaccgtgtg aaataatcac tgcctccaga tcattcaaag
     2281 tttcccccat tttagtcgca ttatagacta attttttatt agcgccagca tcgaagagat
     2341 atttcttccc tgagtagtta attaagagag ataacccatg tccactttta aagttcaaat
     2401 ttattcttga gttttcaaat aaaaccttga tttccactat aacatctcct ttcacatgaa
     2461 cgtgtattca tatattgtag cacattaagt tctatttttt gttgtaatta ccgaaaaaaa
     2521 tattaatgga cgctttttac gctttatttc gtatgtggaa gaaaatttct taggatgtgg
     2581 cgggggattg gggcaaagct aaattccaat tacagtgatc atttaattag acacctttaa
     2641 atacccacac tttcatcaac actataattt agggaaagaa aagtgttggc atgatataga
     2701 aaaaccttta attaacagcg tttcctaaaa ttggcacgca tcttgcttat agaaaagcgt
     2761 aaggatagga ggaatgaaaa tggcaactat aattcttgcc agccatgggg aatttgctca
     2821 aggattaaag caaacagcga caatgattat tggagatagt gtaccaattc atgccttgtc
     2881 agcatttaga gatgaagatg aatctatttt ggtacaaata aaaaaacttt tagccacaat
     2941 agatatagaa gaaacctaca ttttaactga tattctaggt ggtagtgtga ataatgatat
     3001 gctcactatt attaaagagt atgagggatt gcaattaatt actggaatga acttaccttt
     3061 agttatttct attgcaacct ataatggaaa aattggggaa agtgagctag aaaagcttat
     3121 taaagagagt caacaatcag tgattgattg tagaaaatta ttagtagaac aacttactgg
     3181 aggagatgac ctatgattaa gttagtacgt attgaccatc gtttgttgca cggacaggta
     3241 gtattttctt ggagtaaatc attaaatatc aatcgtatta ttattgccaa taaagaggca
     3301 gcgaatgatg aattcaaaaa aatgtctttg aatttatcta aaccgactgg cattaaatta
     3361 acaatttttt cagttgaaca gttactagaa aaaatgccta aaatcgaaac acttaacgaa
     3421 aatatcatgc ttatttttgg taatacaaaa gaaattcgtc aattttgtga agcctatcct
     3481 aaagtacaag aaatcaacta tggagggata atcaaaaaag aaggttccaa gcaatttagt
     3541 aatgccattt tcttgaatga atctgagcaa gaagatgcca aaaaattaaa agctcttggc
     3601 attaaacaat ttattcaaca ggtaccaact tctaaaaaag aagatttgaa tacaatgtta
     3661 taaaggagga atgaaaatgc tcgttcagtc aattggttta gggttaatcg gtgttttttg
     3721 tattttagac tcaaggcttt taggaagaat gaattttgaa cgaccgttga ttgtcagtac
     3781 gcttgttggt ttggtacttg gagacatgga aaaaggatta attgttggag cctctttgga
     3841 attgatgtcc ttaggattag taaatatcgg agctgcttca ccacctgata tgaatatggc
     3901 atcaattatt gctacagcct ttgccatttt atcaaatgcg aatgcagaag cagcattaac
     3961 gattgccatt ccaatttcag tgttaggtca aatactaggt atcttaatgc ggacgatttt
     4021 gtcaaatttg actcacgttg cggatcgctt tatcgaacaa ggaaaattta gccaagcaag
     4081 gagaattcat atactttatg gctcgggatt atatgctctc atgtatttta ttcctatttt
     4141 tctagcaatt tattttggaa cgaatcttgt ttctcagatt gttgatgcga ttcctgagtg
     4201 gctaacaaat ggcttaacgg ttgcaagtaa aattttacca gcatatgggt ttgcgttgtt
     4261 attacaaacg atgttaacga aaaaaatggt gccattttta ttacttggat ttttaattac
     4321 tgcttattct ggattgggaa tcattggtat tgcagccttc gcatgtattg ttgcgtttgt
     4381 catggttcaa gttcaaggta aaaactcaaa tggtaaccaa aatgagccag atccattaga
     4441 tgacttataa ggaggtagat taagtgaaag agaaagatca aaatgcatgg aaatatcggc
     4501 agttcttatg gcgttcatgg gcaattcaag cctcatggaa ctatgaacga caaatgaaca
     4561 tgggttttat gtacggaatt gcaccaattc tagataacat ttacaagaat ccagaagatg
     4621 aagcaatgaa gaaagaagct tacgagcggc atatgatgta ctacaactgt acccctcaaa
     4681 caagtgcatt tgtgttaggg ttaactgctt ctatggagga gcaatactac gaagaccaag
     4741 aaaactttaa tccggaatca atcagtgcag tgaagacttc tctgatggga ccgctatctg
     4801 gtgttggtga ttctttcttt caaggaacga ttcgggtatt agcctttgga ctaggaatta
     4861 atttagccca acaaggtagt attttaggtc caattctagc aatgttaatt tcctttgtac
     4921 cttccttttt agttacttac tatggtggga aaattggcta taacatgggg aataaatact
     4981 tgtctaaact gtatcaagaa ggtttgatgg ataaagtaat gtatgtttgc tccattgtgg
     5041 ggttgatggt cattggttcg atgattgcca gcatgatcgg gattacaaca ccaattcaaa
     5101 tgggtaaagc ttttgtctta caagatgtat tagatagtat tatgccacaa tttttaccat
     5161 taggattaac cttcttcatg tactggttat tgcagaaaaa ggtcaaaaca ggatggatgt
     5221 tggcaatctg tttagtcgga ggaattattt ttagtttgtt aggtatctta caataaggga
     5281 ataaccaata aatttggttg aataatataa ataaggagga attcaattga tgaattcaaa
     5341 agaaattgtt aaagaaatcg tagcgaaaaa agaggtaaaa tcaatcgtat ttgttggctg
     5401 tggcgcttca aaagcggacc tttatcctgc aaagtatttt ctagaccaaa atgcgaagca
     5461 gttacggatt agtcattaca cagccagcga atttaactat gcaacaccag catctgtaga
     5521 tgagtcaact gtcgttattt cagcttcttt aggaggtacg actccagaaa cagttgaagc
     5581 taacgcagta gctaaagaaa aaggtgctac agttattagt ctaacacgaa gcattgactc
     5641 accgttaaca aaagatgcag attatgtaat ttatcatcga tttgcagaga actatgctgc
     5701 taaattagaa aaaacaggct actgtttaga attggcagta gaacttttac atcaagtaga
     5761 aggttatgac cattatgaag caatgcaaga aggatttgct actatctatg atcttgccca
     5821 aaaaagtgca gaatcagctc gtaaagatgc gaagaaattt gctgaacgct ttaaagatga
     5881 aaaagttatt tatgtaatga gtagtggtgc tacacatgaa gtagcatact caacatcaat
     5941 ttgcttgatg atggaaatgc aatggattaa ttctggtacc ttccattcag gagaattttt
     6001 ccacggacca ttcgaaattg tggataaaga cgtaccgttt atattattaa tgaatgatgg
     6061 aaaaactaga aatatagatg ctcgagcatt aactttcctt gaacgctttg atacgaaaac
     6121 agaagttgta gatgccttgg attatggctt gtcttcacat attgctaaag aagtcttaga
     6181 ctactttaac ccattcgtga ttactgcagt atttagagtt tatgcagaag aattgtcaga
     6241 agcaagagaa catccattaa ctaagagacg ttatatgtgg aaactaactt attaaaaaat
     6301 agatcaaact aaataaggtg gcttgagaaa ttaagccacc ttgttttctt caatgtgatt
     6361 ttatacatat ggtaaaataa ctagtacata tggtaaaata actagtacat attgtgaaag
     6421 caggtggcag atgcagcgat taaatgacta tctttatcaa ctaacattgc ttttgaaatc
     6481 tacgccttca gataattatt cagctcgcag tatttcgcaa gctctacagt tgaatagaag
     6541 tacaatcagt agctacttaa atgaaggtgt tcgtgaaggg cttttcataa aagtaaaaag
     6601 ttacccggtt ttatttttac atagaacagc tcttgaagaa ctacatatca cactgaataa
     6661 ctccgaaata gaatcaattg aaagcttgtt aacaatttct caaaaacccg cattagatca
     6721 agtaattggc tctaaaggaa gtttgaaaga agcaattgat caaattaaaa cggcagtctt
     6781 atatcctgga aaagggttgc ctttattatt gatcggcgct agtggatcag ggaaaacctt
     6841 tctagcgaat aaaatatatg aatatgcagt agaagaaaag gtcattcaca catcggcacc
     6901 tttcatagat tataattgtg cacaatatgt gagcaatcca gagttactat cctctgcttt
     6961 atttggctac acgaaaggag catttaccgg agcaagccag gagcatactg gtttgctaga
     7021 aaaagccgat ggaggagtat tgtttttaga tgaagtgcat cgcttatctg aagaagggca
     7081 agagaaatta tttacattta tggatacggg tgaattctct cctatggggg ataatagtat
     7141 tcggaaaaaa gccgatgttc gattagtctt tgcaacaaca gaaaatatat atacgacttt
     7201 cttaccaact tttcttagga gattgccagt tattgttaat ctacctagat ttcaacaacg
     7261 tccgtcgttt gaacgtctgt cattgattga tgaatttttt gtttctgaga gccaaatttt
     7321 agctaaggaa ctatctgttt ctgatgcatt gattcatttc ttaatgaata gtgattttga
     7381 aggtaacgtg gggaatatta aaaatattat caagtatgct tgcggaaacg catatatcca
     7441 ccagaagagt cagcaaacaa ttcaagttaa attattggat atgcctttag agtacagtta
     7501 taaattcaag gagcaactaa ataaacccag aaagaaaaga gcagatcgaa tctactatcc
     7561 agaagaaaca cgacaagtgc aactagaaag aaacaatcag ctttttgttc aattttttga
     7621 ccaattactt actggattct ctgaagtgat tgaaaataac aaggatatta aactattttt
     7681 agaagaaatg gttaccaagg taacacaagt aatggatacg cttatttttc aagaggatta
     7741 cgaaaaagag cagtctttat acgccattct aaactatcat attcgtcaaa gtattgattt
     7801 tatgcgagaa agctacgggt ttgaacaaga tggtaaccgg gtagtcgctt tggccaacta
     7861 tctatatgtc aaggataatc aagtgatttt tgaaaatagt cttcaagaaa agaaaaccaa
     7921 agatcagctt aacgaatttt ttgctaatgt tcttgaaacc ccttattggt atgcaaaaaa
     7981 aatcttaagc cttttatctg agtgtttaga tcaacctgtg tatgaagagg acattttctt
     8041 tattacgcta tatttttata gtttgaatgt cacgaatgtt aaaacaggta ttaagagtat
     8101 tgtgctagct catggttatt ctacagctag tagtatggcg aatgttgcca accgtatgct
     8161 gaataagaac gtttttcaag cttatgatat gcctttagat attacattag agaaaattga
     8221 agcaaaattg attcaattcc ttggagatta tcgaacagat tcaggcttga ttttattggt
     8281 agatatgggt tcactaaacc aactaggcgg tttattagtg aatcatctaa atggaccact
     8341 gttaatcatt gatcatatca atacaccgtt attattggaa gtcggccaac aagtattaaa
     8401 caataaaagt atcaccgaaa taggagcaga aattgaaaca agtcttactt tcaaaaagca
     8461 gttactactt cccaagaaaa agaaaaagaa agccatcatt acttgttgtt atacagggat
     8521 tggtagtgcg acccagattc aggagatttt aacgaaatgc ttgaaagatg cagttagaga
     8581 attagtaatt attccgtatg attacaaaaa gctgttagaa aacaagaatt ttgagactcc
     8641 ttttcaatta tacgatgtca tcatgattgt aggtacagaa gatcccaaaa ttaatcagat
     8701 tccatatatt ggattagatc gcctgattaa tgggggaagc attggcgaat ttgttcatta
     8761 cttggaaaaa gagctgacta ttgaagtgaa cgatttacaa aaagaattaa ttttcaattt
     8821 ttcaattagt aaaattgtcg aaaatttaac cattttggat ccagataagg tgctatcttt
     8881 tgtacaaaaa gcaattaaag aattatcgaa gttattaaat tttgattttt ctaataatca
     8941 gctgtttttg ttgtaccttc actgtagttg tatgattgaa cgaattgtac gtaaagaaag
     9001 tgtggatgag caagaggaca ttgaagaata tatgcaagca aatggagaaa taatggataa
     9061 aattcatagc gctttttttg agattgaaag ggaatacaca attgaaatac cagatttaga
     9121 gttgcgatta ttgagcgata ttgttcaagg ataggagtga attcgaatga caatgggagt
     9181 aatttttgat atggatgggg tactcataga tagcgagaca ttttattttg agagaagaat
     9241 gaacttcttt caagaactgg agatagatcc aggatcaaac cagattgatg attatgtggg
     9301 gaaaacagaa gctgcaatat gggaaacatt agttcctgag gacaaatcat taagagagga
     9361 actttatccg aaatatgtag attatcgaaa aacgcatcca attgatttcg ctaaagcttt
     9421 acgaaaagaa gtgaaaccgt tacttgactt cctcaagaag cgggatatac cattggcact
     9481 ggcatcttct tctccagctg tcgagataga gagtatgctc attcaatgtg aacttactga
     9541 atatttttcc tttgttataa gtggtgagtc attaaaacaa agcaaaccac atcccgaaat
     9601 atatttaaaa gcgaaacagc aattagactg tgacttcttt attgcagtag aggattcaac
     9661 gattggtatt aaatcagcaa aggcagcaaa tatctatacg gcggcactaa aacaaccaat
     9721 gcaaatcgat cagagtgaag cagacataca aattgaaagt ctacaagaac tggaacaaat
     9781 tgttttagaa aaaggttagt gaattaatgg aaataaggct atatatctgt gctagctatt
     9841 ttgactaacc aaaaaaactt gctataattc aggtgtagta aaaggtgctg gtaacacctt
     9901 ttacgaaaat gcttcggcag tgataatggg attggctttt taagtttttt attttgttcg
     9961 caatccctaa ggtcatgtga atgatcctag ggattgctag aatattttgc aacagaacca
    10021 aaatacgaat agttatcaag cagccatatt gactgcggtc aatttaggag gggatactga
    10081 tactactgct gccgtaactg gtgctcttgc gggtattctt tacgggggtg aagtgatccc
    10141 tgaaaattgg agaaaatcgc ttcaaaatga ccagcttctt aaaacgatca gtcagagatt
    10201 ttgcgatacc gtgctatctc aaagaatttg aataatggat atgatgcaaa tcttgtttgt
    10261 actaacgttg tattgacaaa aaggatttta tttagtacaa tgttagtaca aatgatgaac
    10321 ggaggtagaa tcatgtctca atcaaccatt acatttagga ttcccgacga tgaaaaagaa
    10381 ctggtattag aatatgcaaa agcacacaat tcttcattga ccgaacttta tcgaaatgct
    10441 gtactggata aaatcgaaga tgaaatcgat ctacggactt tacggagtgc aattgaagtt
    10501 tccaaagaga aaaaagagag tggtatttct caagaggaaa tggagaaact gctaaatgaa
    10561 ttataaagtc atctacatgc cgcaagccca gaagcaatta aaaaaaatgg acagaaacca
    10621 agctaaaata attgtcgcct ggatcagaaa gaatttagaa aacacgactg acccgcgtca
    10681 gcacggaaaa ggtttgactg gaaataagag tggggaatgg cgctatcgaa ttggaaacta
    10741 tcgaatattg gctaatattt gtgattctga aattgaaatc cagatattct caattggaca
    10801 tagaagtaca atatataaaa gataaccgtt tttggaacga agtagagttt cgaaagtcaa
    10861 tgtataatct tttgaatttt gcataatacc acaggtagaa actacccgat actatcggtt
    10921 ggtttctgct tttttatggc tctttgtcaa ataggactga tagagtgaga taagaacatc
    10981 taaggtagaa ttccttttct actttagatg ttttttgatt cataggtaat cagattattt
    11041 agtaagaaaa ttctggtctt cattttccga aagcttcgaa agccataagc gactcgtttc
    11101 aatgctttga tgtgggtatg cagattttct attttggcat ttgaataagg caattcgagg
    11161 gctaaacgaa tgccggattc atagtttata aaagcttttt ttatagaatg cagttctttt
    11221 ggaacggaat tgggcatcgt tcttacaagt ttaaagaaag tgtccgcctc tttgtcgtga
    11281 aacgcttgaa gaatttcttg atagtaaaaa taggcgattc gtaattcgtc agagatcgaa
    11341 agcagacgat ccaccacttc actttcggtg agatacgccc aaccaaaatt gcgccatttg
    11401 gtccatttgt cataaacaag cttgtcctgt cgtttgatca gaagccgaga caacgccttt
    11461 aattgtcgat aatatttggc ttgtgttgga tcgtttcgat caaagctttt catgattcgt
    11521 acgcgaatat cctcaaattt acgaatgaga tgtttgacaa tgtgaaaacg atccacaacg
    11581 agttttgcct ttggaaaaca ttcctttatc agagaggcat aagaaacatt catgtccgtc
    11641 acgatgacct ttaccttcaa tcgtgcgcgt cgttcaaatt gcataaaata agaaacgaga
    11701 gcctttttct tccgtgaagg aagaatatcc agtaattttc cagtatcgcc atccatacaa
    11761 gaaaaggagt agggaccgac ttgatttttc agtgaacgaa attcatccat taataaacaa
    11821 cgcggtaacc aatttctttt tacttttgtc atggggatca gagaagcgag tgtccgagaa
    11881 acggtcgacc aagaaacgcc gcaatgctta gcaattgtcg tcattgcttg tttttcagtt
    11941 agctcttcta aaattttata gcgcacttgt ttagcgataa agcagtttct atcgacaatg
    12001 taggtattcg ccgtaaaata ggtgtggcag ccacgacagt ggtagcgttg tttcgctaaa
    12061 gcaagataag tcagttggtt cgcacattta ttaagttgaa tgagcgattt tttctttccg
    12121 ttcttaacga tcatgccttc atgattcatc tgtttacaca aaggacagcg acgaatttct
    12181 ttacttaacg tcgcagaaac aacaagactc ttgatattct taatgctctt cgattccaca
    12241 tttgtgatga aaatgttttt atctttgatt ccaagtagta gtttgatatg atgaagatca
    12301 ggcatacaga acgctccttt gattgtgttg tggtg
//
LOCUS       DAZKCH010000079        12200 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000079 DAZKCH010000000
VERSION     DAZKCH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.080"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(83..640)
                     /gene="frr"
                     /locus_tag="ACG84X_002270"
     CDS             complement(83..640)
                     /gene="frr"
                     /locus_tag="ACG84X_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFP9128102.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(643..1365)
                     /gene="pyrH"
                     /locus_tag="ACG84X_002271"
     CDS             complement(643..1365)
                     /gene="pyrH"
                     /locus_tag="ACG84X_002271"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFP9128103.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1501..2382)
                     /gene="tsf"
                     /locus_tag="ACG84X_002272"
     CDS             complement(1501..2382)
                     /gene="tsf"
                     /locus_tag="ACG84X_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFP9128104.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2481..3263)
                     /gene="rpsB"
                     /locus_tag="ACG84X_002273"
     CDS             complement(2481..3263)
                     /gene="rpsB"
                     /locus_tag="ACG84X_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFP9128105.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3622..4101
                     /locus_tag="ACG84X_002274"
     CDS             3622..4101
                     /locus_tag="ACG84X_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFP9128106.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4318..5409
                     /gene="phnW"
                     /locus_tag="ACG84X_002275"
     CDS             4318..5409
                     /gene="phnW"
                     /locus_tag="ACG84X_002275"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFP9128107.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5402..5530
                     /locus_tag="ACG84X_002276"
     CDS             5402..5530
                     /locus_tag="ACG84X_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFP9128108.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5534..6079
                     /locus_tag="ACG84X_002277"
     CDS             5534..6079
                     /locus_tag="ACG84X_002277"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HFP9128109.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6533..8224)
                     /gene="argS"
                     /locus_tag="ACG84X_002278"
     CDS             complement(6533..8224)
                     /gene="argS"
                     /locus_tag="ACG84X_002278"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFP9128110.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8644..9591)
                     /gene="arcC"
                     /locus_tag="ACG84X_002279"
     CDS             complement(8644..9591)
                     /gene="arcC"
                     /locus_tag="ACG84X_002279"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFP9128111.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9706..10725)
                     /gene="argF"
                     /locus_tag="ACG84X_002280"
     CDS             complement(9706..10725)
                     /gene="argF"
                     /locus_tag="ACG84X_002280"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFP9128112.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10816..12045)
                     /gene="arcA"
                     /locus_tag="ACG84X_002281"
     CDS             complement(10816..12045)
                     /gene="arcA"
                     /locus_tag="ACG84X_002281"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFP9128113.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3342 a         2529 c         2203 g         4126 t
ORIGIN      
        1 ctttttttaa tttttaaata aaagaaatat aaataaaaac agaggaagcg gaatgatccg
       61 cccctctgtt tttatgattt tattaaactt ccaataattc tttttcttta tcagcagcga
      121 tcttatctac ttctttgatg ctgttatctg tcaatgtttg tacgtctttt tctaatccgc
      181 gcaaatcatc ttcggtaata tcaccatttt tttgttgttt tttatattca tcgatcgcat
      241 cacgacggat gttacgaatc gcgatttttg cattttctgc ttcttttttc acatctttag
      301 ctaattcttt tctgcgttct tctgtcagtt gcgggataac taagcgaatg acatttccat
      361 cattggttgg actgattccg atatcacttg ccataatagc tttttcaaca tcttgaagaa
      421 tgctcttgtc aaaaggtgtg atcattaaaa cacgtgcttc tggaatttgg attgatgcca
      481 tttggttcaa tggtgttggc gcaccgtagt agttcacagt aatacggtcc aaaaggctag
      541 cgttcgcacg gcctgcgcgg atttgcccaa gttcacgttg aagattttgt gctgcttttt
      601 tcattttttc ttttgcttct gtcataattg catctgccat ttttatttcc cccttacagt
      661 tgttccgata ttttcgccta agattgcacg gcgaatattt ccgtgttcat ttaaattgaa
      721 gacaagcagt ggaatatcat tatccatgct tagtgaactt gcagttgaat ccatgacttg
      781 taatcctttg gcaataactt ccagatgagt cagttcttca aattttactg catttgcatc
      841 tactttcgga tcagcagaat aaacaccgtc tacattgttt ttagccatca ggataacatc
      901 tgcgccgatt tctgccgcgc gtaatgctgc tgttgtgtct gtcgagaagt acgggttgcc
      961 ggtaccgcct gcaaagataa cgatccgtcc tttttctaaa tgacgttctg ctttacggcg
     1021 aatatatggc tctgcgattt gacgcatttc aatcgaagtt tgcacgcgtg tcggtacacc
     1081 cacgttttcc aacgtatcct gtaaagctaa ggcattcata actgtagcta acatacccat
     1141 gtaatcagct tgagcacgtt ccatgcccat ttgtgctccg atttgtccgc gccagatatt
     1201 tccgccgccc acaacgattg ccatttcaac gcccagctcg tgaacttctt tgatttcttg
     1261 gatgatttct ttgattactg gtggtttgat tccaaatcct gcgtccccag ctaaagcttc
     1321 tccactcaat tttaagacta cacgctgata tttcggtgtg accatgttca ttcctccaat
     1381 attttctatt gccattttac catacttaga tgatttcgac actctaagac tggtttttct
     1441 tgttttgctt aaaaaaaggg agcgcacaaa ccgtgcgttc ccgtctgtta ttcaacagaa
     1501 ttattttttc acttggctca taacttcttc tacaaagtta tcttcgcgtt tttcgatacc
     1561 ttcgccaact tcgaaacgta cgaatgtttt aacagttgcg ccttttgatg caacgtattt
     1621 ttcaacagtc atatcaggat ctttaacgaa tggttggtcc accaaagcga tttctgcttt
     1681 gaatttcttc aagcgtcctt ctaccatttt ttcaacgata ttcgctggtt tgccttcgtt
     1741 caatgcttgt tctgtaagaa cagttttttc atgttctaat tcagcttctg gaatttgtga
     1801 ttcgtttaca taacgaggat tgatagctgc tacgtgcata gctacgtctc ttgcaactgt
     1861 ttcgtcagtt gttccatcta gaacagtcaa tacggcaata cgtccgccca tatgcaagta
     1921 tccaccaaat gcagcattgt cgtctttttc tacaacttca aagcgacgga agctgatttt
     1981 ttctccgata acttgagttg cttcgatcaa gtcagattca attgtacctt tatctgtttt
     2041 gattttcatt gcagcttcca tgtctgctgg tttgttttca gcaacaagtt ctgcaatttc
     2101 ttttactaaa tcttggaaca tttcgttttt agaaacaaag tctgtttctg agtttacttc
     2161 aacgattgct gcagtgttac ctttcacagc aactgaagcc aatccttcag ctgcaatgcg
     2221 gtcatttttc ttcgcagcct ttgccattcc tttttcacgt aaaagatcaa ctgctttttc
     2281 catgtcgcct tctacttcaa ctaatgcttt tttcgcatcc atcattccta cgccagtcat
     2341 ttcgcgtagt tcttttacca ttttagctgt aacgtctgcc atgtttaact cctcctgtgt
     2401 gtttttcttt ttaaaaaaag ctgcttcaaa ggagagtgag gcttgtcgcc cagcctttga
     2461 aacagctcca tcattcaaaa ttattctgct gaagaattgt cgccttcaac aacatctacg
     2521 atttcttcga ttgatgttgc tgtgttttct tctgtgaaat cttcttcaac tacttgatct
     2581 tcaccttggt ttccttcgat gaaagcatca gccatttttg aagtaatcaa tttaacggca
     2641 cgaattgcat cgtcgtttga agggattact acgtcgattt catctggatc gcagtttgta
     2701 tcaaccatag ctacgattgg gatatttaat ttgtgtgctt cttgaacagc aatacgttct
     2761 ttacgtgggt caacgatgta cattacatct gggattcttg gcatatcagc gataccgcct
     2821 aagaattttt caagacgttc acgttctttg ttcaaaccag caacttcttt tttaggtaga
     2881 acttcaaaag ttccatcttc ttccattgca ttgatttgtt tcaaacggct gatacgtttt
     2941 tggatagtat cccagtttgt caatgttccg cctaaccaac gatggttaac gaagtattgt
     3001 cctgcacgag ttgcttcttc tttgattgct tcttgtgctt gtttttttgt acctacgaat
     3061 aatgctacgc cgccttcttc agcaacgctc ttcatgtaat cataagctgc atctactaat
     3121 ttaactgttt tttgcaagtc aatgatgtag attccgtttc tttctgtgaa gatatatttc
     3181 ttcatttttg gattccagcg acgagtttgg tgaccaaagt gtacgccggc ttctagtaat
     3241 tgtttcatag aaattactgc catgtttgtt tcctccgatt tggttttatt tttcctcttc
     3301 ttatcttcta ccttgccggc aaactttttc aagcacctac cgacaatcca ataagaatgt
     3361 ggatttgctg atgcataaag caccctcagc tattatacag acaaaagatc cgtatcgcaa
     3421 gagcaaatat acttttctgc tcaacattca atagtttacc tgaaagataa aaagaattca
     3481 agaaaaacag tagatttctc tttgtttctt tattatcctt tttccataaa ataattttag
     3541 gtataaaaga cgaatattat tgggcaatcc ttcttttttt tgttatgata catgtgaaat
     3601 ctttcgtaaa ggagaaagaa aatgcgcaaa gctcaaagac atttgctgat taaacaagtc
     3661 attgaagaat tcccgatccg tacgcaagaa gaactattaa acaaacttgg gcattatggc
     3721 gttaccgcca cgcaggcaac gatttctcga gatatccgtg atctaaaaat cgtgaaggca
     3781 cctgatgaaa atggcgtttc ccgcttcgta ttgtttcgcg aaaaaggaac tcctgagact
     3841 aggactgagg aagaggatcg gctggttcaa atgattgaag acattgtatt gaaagtcgaa
     3901 cgagtccact ttttgacgat cgtcaatacc ttgccagaca atgctcattt atttgcatct
     3961 gttttagatg agatcaaacc tccctctatt gtcagtacaa ttgctggatt cgatacgatc
     4021 atggtcatct cggaaaatga ggaggacgca aaacgagtag aagaatttct tcaccatcca
     4081 actgaagtat cactttttta atcagagcac gtattcctaa tatggaatgc gtgttttttt
     4141 attttcaata ttttccttat tgaataaacc tttacactct ttacaaaaat acatcatttt
     4201 ttattcaaat ttttcaacac cttgattgaa tcacaataat catcatttat attggatgtt
     4261 aacaagagca gcttcttgct ctttgtgtat ttcaaaaaag aaatgaaagg aaatcatatg
     4321 tataaattat taacttctgg accattgacg acttctgaaa cagtgaaaaa tgctatgctg
     4381 atcgatcatt gtacttggga tcaagaatac aaagaaatta cacaatggat aagaaaaaaa
     4441 ttattggatc ttgctcaagt atcggaagga atatacacaa cggtcttaat gcaaggtagc
     4501 agctccttcg gggtagaatc ggtattaagt tctgtgatca ggccagaaga tactgtactg
     4561 atttgttcaa acggcgcata tagacaacga atgatcaaca tgtgcgaatg tctgaaactg
     4621 aactataccg tttatgaggt atcggaacat caaatcctcc aagctcatgt gattacacag
     4681 ctgattgaag agaatccgtc tatctccgca ctagcaatgg tccatagcga gactacttcc
     4741 ggtattttga ataatttgga agagattgct gctgtcacac aagaaagaga tcttttgttt
     4801 atagtggacg cgatgtcaag ctttggtggg ataccgattt gtgtagccga actagggatt
     4861 gattttttga tttccagctc aaacaaatgt attcaaggtg ttccaggctt ttcttttgta
     4921 cttgctaata aagcggaact ggaaaaacga aaaaatgtta gccgaagttt gtcacttgat
     4981 ctatatgacc agtaccgcgt gatggaaaac gagaatggca aatggcgttt cacttcccct
     5041 acccatacgg ttttggcttt tcaacaagcg ctgaaggaac tagaggcaga aggaggaatc
     5101 gaaactcgat attcacgtta tctcgccaat aatcatgtgc tacgacaaaa aatgacagag
     5161 atggggttcc agcctttcat tcaagaatat caggggccat tcatcacctc ttttctttac
     5221 cctaaggact ggcgatttga ttttaatcat ttttatcagt atttaaagca aaatggattt
     5281 gtgatctatc ccgggaaaat cagcgatcat gaatgttttc gtatcggaaa tattggcgag
     5341 atctatccgg aagatatttt ggaactgaca gcaattatca aagactataa ggagaacgtt
     5401 aatgattaaa actgtaattt ttgattgggc aggaacaact gtggactttg gctgtatggc
     5461 tcctgtccac gcttttagaa atgcttttct agaaaaagga acccaactga ctgacaaaga
     5521 aatccgctaa ccgatgggaa aattaaaatg ggatcatatc caacagcttc tttccctccc
     5581 ttctgtcaaa aaacaatgga tagctattta tggacaacta cctcaggaaa aagaggtgga
     5641 ggaattgtat caacaatttg aacattatct gtttaaagat ttggtcaagc attctacctt
     5701 gaaacccgac acattggaaa cgatcgaacg gttgagaaac gctgggatca atattggttc
     5761 cacgaatgga tttaatgctc ctatgatgac aatcgtagca gaaaccgcaa aaaaagaaag
     5821 gtattcacca gacttcatgg caacttttga agacgtcgaa gggtatggtc gaccgtttcc
     5881 ttatatgatc cataaaaaca tgcagtactt caaaaacaag tcggttgatg aagtaatcaa
     5941 agtcggagat acggtctcag atatccagga agggaaaaat gccggagtgt tgacagtagg
     6001 tgtaattgaa ggtagttcgc taatggggat ttcttatgat gagtaccaaa aattagagat
     6061 ggggaaaaag atcgtttaaa acagtctgtt gctcttagat tccaacaagc cggcgctgat
     6121 atttgtgtaa acaatttaaa agagttaaca gaatacattt tgtacgctga caagaatcca
     6181 gaatgacttt tatacaaaat aagaggttgt gaaaaagctg tcctgtatca agtaataaaa
     6241 acagccaagc aaaaatagct cctcatattt ttcgtttggt taggcttatt accgcagatg
     6301 caagcttttg aacaccgttt attcgaaaaa aaaaagggag ctgtgacacg acttttgtca
     6361 cagtcccctt atttgcaaac aaacagtgtt taagagacaa cctctccact aaacggtgtt
     6421 cattcagctg actctcggta tttgctcaaa aaacgataaa atttgaaaag ctattttctc
     6481 ttttgtttct ctaatactcg gatcagaacg ctgatttcac attctctttt tcttacatct
     6541 tatctggtgc atgaagtcct agcaaacgaa ggtcttcttt caataataca gtcactgcat
     6601 aaactagagc taagcgtgct tctttttgtt catcatcagc taaaatcttc gtatgagcat
     6661 agtatttgtt gaatgcttgt gctaatttga ttgcatgttt cgcaatcact gacggttcgt
     6721 atttttcccc agcagacaag accgtttcag ggtatttttg aactaattta accacttccc
     6781 agctggtatc gtcattcaat gcatagtctg ctgtttctga agggacaaat cctgcttttt
     6841 ccaacaggct gactgcacga gcatgtgtat attgcacata aggtccagtt tctccttcaa
     6901 atcgaacaac ttcttccagg ttaaagtcaa atgtattcag tcgatcgttt ttcaaatcgt
     6961 ggaaaatgac tgccccaacc ccaacttgtt tagctacagc atctttgttt tccaaatcag
     7021 ggtttttctc gctgatttgt tctttagcag attggattgc ttcatttaat acttcttcta
     7081 ataagacgat ctttccttta cgagttgata attttttacc accttgcgtg atcaaaccaa
     7141 atggaatatg gtgcatgtcg tcagaccagt caaagcccat ttccttcaag acagctttca
     7201 actgtttaaa atgatagctt tgttcattcc ctactacata tagagattgt ttgaagtcgt
     7261 aagtacgttt acggtacaat gcagcagcta agtcacgtgt aatgtatagt gtcgcaccgt
     7321 ctgacttctt aatcaacgct ggattcaggt cataagcaga taggtcaacg atctctgcac
     7381 ctttatcctc gttcagcaaa tgtttttctt ctaaaagttt gacgatttca tccatcttgt
     7441 cattgtagaa agcttcaccg ttcaacgaat cgaaacgtac ttccagcaga tcatagattt
     7501 tattgaattc tttcatcgat tcatcacgga accattgcca taattgaata gcctctttat
     7561 cgccttcttc cagacgtttg aaccaagcac gagcttcttc atttaattct ggttctgttt
     7621 cagctacttc atggaattgg acgtataaac gaagcaattc attgattggt tctgctttaa
     7681 cagcttcttc tgtaccccat tttttgtaag cgacgatcag ttttccaaac tgtgttcccc
     7741 agtcacctaa atggttgatg cggattggct gataaccgat tttttccata atgaaaccga
     7801 tcgaattacc gataactgtc gaacgcaaat gtcccattga gattggtttg gcaatattag
     7861 gagaagacat gtcgattggt actgttcctt gattcccgat gttgctatcc ccataatgtt
     7921 ctttttcttt cactactgtt tgcaaaactt ttttgctgat aagttcttta ttcatgaaaa
     7981 agttcaagta aggtccgaca acttcgattt tttcaaagtt ggcagaatcg attttttctg
     8041 ctaaatctgc agcgatttgc tgtggcgctt ttcggtaaac ttttgctaat gaaaaggctg
     8101 gaaatgcaac atctccgtgt tcagctgatt ttggattttc tagtaattgc tcgacttgtt
     8161 ccagtgttaa atcatctttg acagcgtcat agacagcttt tgcgacaaga tctttattat
     8221 tcatctttat tcctcctaaa gtgttccctt gattgttaaa caaaaaaaat ctctagcgac
     8281 ggcatactta gtatgccatc actagagacg agatttcccg cggtaccact ccaattgtcc
     8341 taaaaaagga ccagctccat ctgatatcgg tagacgaccg tctgtttaaa acagaattct
     8401 ccaagtgcgc ttcgttgtat cttcttcatt cggcttccac cacttccgaa ttcgctagcc
     8461 aagaatgata caagtactct cttgttcaac aaatcttagt cttattaaac tttcttgaat
     8521 tatatcagaa aaaaaaacga aaggctagtc gtttcataaa aaaaaaatcc agatggccta
     8581 aaggagaaga aataccacct ggatagctat aaatcatttc gtaaatacga aagacttaac
     8641 aaattaatca gctacgataa tcgttccttc ttcagaagct aaaagattct cgatattttc
     8701 taaagaagtg atgattgcct tagcgtttgg ttttgcttca acaaatgcaa tagctgcttc
     8761 tactttcgga agcatgcttc ctggagcgaa ttgcttttca tcaatgtatt gtttcatttc
     8821 tgaaacagta acagtttcta atttcttttg atctggtttt tggtaattga catacacatt
     8881 gtctactcct gtcaatacga tcagcaaatc cgcatcgatg atttcggcta atttttctga
     8941 agcaaaatct ttatcgatta cggcttctcg tccttctaat ccagtagctg tttctacaac
     9001 aggaatccca ccgccaccaa cagagactgt gataactcct tgatcgacca gcgtttcgat
     9061 gacacgtgct tctttaatcg agatgggttt aggggaagcg actacttttc tccatccacg
     9121 tccagcatct tctttgaatg tcacagtgga gtcagcattc atttgttctt tggcttcttc
     9181 ttccgtgtag aatggaccga ctggtttact tggatttttg aatgaaggat cattttcatc
     9241 cacaataact tgagtgacta aagaaaccac atctttatcg atcccttttt ccttcagtac
     9301 ttcgcccatg gcgttttgta accagtaacc gatagatcct tctgtcattg caacacatgt
     9361 atctaaaggc attgccggtg ttttctcaga atcagcagct tgctgctgaa tcaataggtt
     9421 accgacttgc ggaccatttc cgtgggagat gatcaattca tctccttgtt cgataaattt
     9481 cactaaatac tttgctgttt ccattaacgc ttcttgttgg gcttttgcac ttgcatccgt
     9541 agacaagatg gcattgcccc ctaaagcgac aactactttt cgtttggcca tttcattcgt
     9601 cctttcttca gttctaccga attttctaga taacaaaacg agccagcgtt ttgtgatttt
     9661 ccctcaatgc tgactcgttt tttcgtgaga tgaatgtggt tatgcttaaa cgcgagggat
     9721 aaacaagtta cctaatgttg ctgccatgat cgctttgatt gagtgcatac gattttctgc
     9781 ttggtcaaat tgacgagcat atttgctgcg gaagacttca tctgttactt ccatttcagt
     9841 gatgccaaag cgttctttca tttgttcacc gtaaacagtg tttgtatcat ggaaagctgg
     9901 caagcagtgc aagaagatca aacgatctgt gttgtgtgtt ttttctacca tttccatatt
     9961 gatttggtaa ggtttcaaca atttgatacg ttcttcgaat ttatcttctt cacccattga
    10021 tacccataca tcagaataaa ggacgtctgc tccgtctaca cctttatcaa catcgtcggt
    10081 aatcatcaat tgtgcaccgg atttttcagc aaagccttct gccattttga cgatttcttc
    10141 ttcaggttgt aattcttttg gtgcaacgat acgcatattc gctcctaaaa ttgcacctgt
    10201 gactaataaa gagttagcca tattgtttcg accatctccg cagtaagcaa cagtgatacc
    10261 ttctactgtt ccaaagtttt cttggatagt taaaaagtca gcgatcattt gtgttggatg
    10321 ccattcatca gtcaagccat tccaaactgg aacaccagag aattctgcta gttcctctac
    10381 cattttttga ctgaatccac ggaattcgat tccgtcaaac atacgtccta gtactttagc
    10441 tgtatcttct gtggattctt ttttacctaa ttggatatca tttgcaccta gatattcagg
    10501 atgtgcacct agatcgatcg ctgcagtagt aaatgcagaa cgagtacgtg tagatgtttt
    10561 ttcaaataaa agcgcaatat tttttccttc tagatagtga tgtgggatac cacgtttttt
    10621 caagtctttc aagtgttctg aaaaatcgat caaatattgt aattcttctt ttgtaaagtc
    10681 tttttctgct aataagcttc ttccttggaa tactgattct ttcatattaa acattctcct
    10741 ttagattgtt tttatttaag attaaagagg aaatcccgac ggcagctgac agtaagactg
    10801 ccgtcaggaa acaaattact tcaagtcttc acggacaagt ggttggctca tgcagcgtgg
    10861 accaccacga cctcgtgaca attcacttga attgatttct aacactttga tgccatagct
    10921 acgaagcaat tcgttcgata cataatttcg gttataagtg actacaacac ctggagcgat
    10981 tgccaatgtg tttgatccat cattccattg ttctcgaggt gcaacgatct catctccatt
    11041 accagttggg atcagtacaa gatcatctaa tccaagagca gctttcatcg tttcgtgtaa
    11101 gttatctgaa tgagtaatct tgatatcatc accatctggt tcgattgtaa agacatccat
    11161 cttaccgtct ttactttgaa ttgctggatg gatagtgaat ttatcgtgat ctaccattgt
    11221 aaatacggta tccaaatgca tcattgcacg gttgttcgga attttgattg ccaacacttt
    11281 ttcaaatcct gaattttttg cgaataggtg gcgtgctaat ttttctaaag ctttcgcatt
    11341 agttcgttga gaaatcccaa cagctactac tttatcgctt aagatcaatt cgtctccgcc
    11401 ttcgatatga tctggatttt cacgatccaa ccatacttcg attcctttat ttgcaaatct
    11461 tggatgatgt ttcaaaatat attctgtaaa catcgattca cgacgacgtg cttcaaaagt
    11521 catcttattg actgtcatcc catttcccat tgatgcggaa gggtcgcgtg taaagtacaa
    11581 gtttggcatt gggtccatgt aaaatggata gtcatcgtct gctgacagat catatagact
    11641 gctagaacgt acttcgatat cttttgtacg aaccccagcc atgattttat ctaccatttc
    11701 ttgcgtttcc attgatagaa ggaactcatg aagaccctct cttacagcat tcgatgcaat
    11761 atgagattca tccaacattt tattcaagaa ttgttctttg acattgcctg cgtcaatcgc
    11821 ttctgccgct aatttttcca agtaaagagt ctcgacgcct tcattttgca atgtcttcgc
    11881 aaagttgtca tgttcttctt gagcaatcgg aagatatgga atatcatcga acaacagacg
    11941 atccataata tctggtgtca aattttccac ttcttgtcca ggccgtttca gtaaaactgt
    12001 ctttaatttc cctatttcag agaaaacgtg aataggttta tccatgttgt gttgcctcct
    12061 tctttttgat tacatgtata ggatatcctc cttttgtaat cactttcata attttgtctc
    12121 attcaaaatg agacattcct cacattaata ttcgataatt aaataattaa acgtttttct
    12181 atttttaagc gtaatttatt
//
LOCUS       DAZKCH010000080        12024 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000080 DAZKCH010000000
VERSION     DAZKCH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.081"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(146..2221)
                     /gene="glyS"
                     /locus_tag="ACG84X_002282"
     CDS             complement(146..2221)
                     /gene="glyS"
                     /locus_tag="ACG84X_002282"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFP9128114.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLAGVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLEDVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2223..3140)
                     /gene="glyQ"
                     /locus_tag="ACG84X_002283"
     CDS             complement(2223..3140)
                     /gene="glyQ"
                     /locus_tag="ACG84X_002283"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFP9128115.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(3526..4344)
                     /gene="recO"
                     /locus_tag="ACG84X_002284"
     CDS             complement(3526..4344)
                     /gene="recO"
                     /locus_tag="ACG84X_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFP9128116.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKEIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFINQMKSWAHVLKTSEKDMSEKEKETPEKEE"
     gene            complement(4487..5386)
                     /gene="era"
                     /locus_tag="ACG84X_002285"
     CDS             complement(4487..5386)
                     /gene="era"
                     /locus_tag="ACG84X_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFP9128117.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5401..5796)
                     /locus_tag="ACG84X_002286"
     CDS             complement(5401..5796)
                     /locus_tag="ACG84X_002286"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFP9128118.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFTVIVGLILFVPKIYHLLFN"
     gene            complement(5780..6256)
                     /gene="ybeY"
                     /locus_tag="ACG84X_002287"
     CDS             complement(5780..6256)
                     /gene="ybeY"
                     /locus_tag="ACG84X_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFP9128119.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6285..8477)
                     /locus_tag="ACG84X_002288"
     CDS             complement(6285..8477)
                     /locus_tag="ACG84X_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFP9128120.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKAIDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNGKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(8501..9472)
                     /locus_tag="ACG84X_002289"
     CDS             complement(8501..9472)
                     /locus_tag="ACG84X_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFP9128121.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10177..11556
                     /gene="brnQ"
                     /locus_tag="ACG84X_002290"
     CDS             10177..11556
                     /gene="brnQ"
                     /locus_tag="ACG84X_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFP9128122.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            11838..>12024
                     /locus_tag="ACG84X_002291"
     CDS             11838..>12024
                     /locus_tag="ACG84X_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9128123.1"
                     /translation="MSYSEFTKELLDILDLNLIFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIK"
BASE COUNT         3286 a         2560 c         2196 g         3982 t
ORIGIN      
        1 ctcacttttc atgagcgttt tgaaaattcg aacaaagaat aaaataacaa aaattattaa
       61 aatagaatta ataacagcta tttataacaa aaaaaacaga gacacagcac gtttcgtgca
      121 tgctctctgt ttttcaaaca aaagactatt ttgtgatgat ttgatccaag cttgctaatg
      181 acaaagccat ggcagctatt tgacttagtt gtgttagtcg gttcttacgt actgctggtt
      241 catcagccat gaccatcgtt tgatcaaaat aattttcgat cagtggacga agagcgacaa
      301 gctggtcgta gttttcgtgg atcgtttggt cagcaaaact tgctttcatt gcttctactg
      361 ctttgtgtaa ttctttctct gcgtcgtttt cgaacagctc agggtctact tctgattgtt
      421 tttcaagctg cgcttttttc gctaagttca cgacacgtgt caaagcttcc attgaaggtt
      481 tgaagtcttc atctgcaaga tgttgtttga acaattgtgc tgctgcaaat acttttgtca
      541 gatctttttg ttccgcattc aaaacagcat cgatgacatc atgacgaata ttcttcgttg
      601 tcaataattg gcgcagacgg cctttgataa agtcgatcac ttgttgttgc ccttctgata
      661 aaccaatgcc gaaacgatcc gtatctttac tgataacatc gctaatcgtt tcttgcagaa
      721 cagacaaagg aaaggcccat tttttcgatt cgatgatccg aacgacaccg tatgcttggc
      781 gacgtaaggc ataaggatcg tttgacccgc ttggaatcat cccaactgca aagaaagaaa
      841 agatgctatc taatttatct gcaatcgcta aaacagaacc tactgtagac tgaggtagct
      901 ctccttcact ggatataggc atgtaatgct cacgaatcgc tgtcgctaca gcaggtttct
      961 cgcctttcag aagagcatat ttttcgccca tgatcccttg tagttcagga aattccccta
     1021 ccatgttggt tactagatca aatttataga tttcagcagc tcgttgcaaa tccatcaatt
     1081 cttcctcaga tagtcctact tgttcgccaa tgatacgggc aatgacttgt acccgttgca
     1141 ttttctcata gatactaccg attttttcat ggaaagtaac agtttttagt ttttcaacgt
     1201 attggtcgat tgaagctttc ttgtcttcat tataaaagaa ttccgcatct tctaaacgag
     1261 ccgtcaatac tttttgattg cctcgaacca catcttccaa ttttacccga tcaccattac
     1321 gagcagaaat aaaatgagga agcagcatac cttgatcatt ccgtacctcg aaataacgtt
     1381 gatgttcttt catagaagtg actagtactt cttcaggaac agaaagatat ttttcttcga
     1441 agtcgccaga aaagacagtt ggatattcga ctaaattgtt gacttcttct agtaaatctt
     1501 cgtctagatc aataacccag tgattttttt ctgctaattc gtttgcttgt gtaacgatca
     1561 tttcttgtct tttttgcgga gacgcaatga cgaattgttc attcaatttt tcttcatatt
     1621 cttttgcatg cgcaaatgtc acatcttcgc ctaagaaacg atgacctcga gaggctctgc
     1681 ctgttttgac atccaagatt tcgaatggga ttacttcgtc atctaacaat gccacgatcc
     1741 agtgaatagg gcggatatat tcaaaatcgt attctgccca atgcatcgtt acagggaaag
     1801 tcaaactttt gatcacccct gctaagcctg tcaatacttc ttttgcttcc ttaccatgag
     1861 tgtatttcgt tacatagaca tattccacac cttttaattc tctaaaagtg atagcgtctg
     1921 tcgtcagacc ttgtccgcgg acaaatcctt ccgctgcttt cgtccagttt ccatctgcgt
     1981 ccaaagcaat ttttttggct ggtcctttga cttcttcttc actgtccgct tgtcgttctg
     2041 gaatatttgt tactttgatt gctaaacggc gcggtgtgga aaatgtttcg atcgtatcat
     2101 aagtcaattg gttttcatct aaaaattttg ctgttttttc ttctaattgt ttcatgcttg
     2161 gtgtgacaac atgggcaggc atttcttcca gcccgatttc aagtaataag tcttttgcca
     2221 tcttattcag cctccttcac ggtttctgga tttgctgtgt ttttattcaa caaagggaat
     2281 cctaattttt cgcgttctgc cacaaagatt ttggctacag cacgagccat gttgcggatg
     2341 cgagaaagat aaccggcacg ctctgttacg gatactgcac cgcgggcgtc taataagttg
     2401 aatgtatggc tacatttcaa gatataatca tacgccggat gaacaagatt ttcatcgata
     2461 cagcgtttag cttctttttc aaaacgatca aagttgctta gtagcaagtc ttggtcgctt
     2521 acttcaaaag aatatttgga atgttcatat tctggttgtt tgaagatctc gccatatttc
     2581 acgccatcag cccattctaa atcatagaca ctttcaactt cttggatata agaagcaaga
     2641 cgttctaatc cataagtgat ctcagaagtt actggtttac aaggcagtcc accaacttgc
     2701 tggaagtacg tgaattgtgt gatttccatt ccgtcaagcc atacttccca acccacaccg
     2761 gcacagccca tggatgggtt ctcccagttg tcttcaacaa aacggatgtc gtgttctaat
     2821 ggatcgattc ctaaaaggcg caagctttct aaataaagct cttgaatatt ctcaggtgaa
     2881 ggtttcatca ccacttggaa ttgatgatgc tgatacaaac ggtttgggtt ttcaccataa
     2941 cgtccatcag ctggtcggcg agatggctct acgtaagcag cattccatgg ttctggtccg
     3001 attgcccgta aaaaggtata tgggctcatc gtacctgctc ctttttctgt gtcataagct
     3061 tgcatcagca tgcagccgtt tgatgaccaa aatttttgta atgttaaaat catatcttgg
     3121 acggtcaatt ttttactcat ctgttttgcc cctttcaatt ttaaagcgtt gctgtcaaat
     3181 aagaatacag gaaagaaaac gacaaaaaat ccctatgtct gattacagac atagggacga
     3241 ataattcgcg gttccaccct acttccgaat aaagattcgg cagcttcatt tatcgtactc
     3301 gcaagtgcct cttcaaaaat cgtttgggtc cggctcccac tctcccgaac tcgctaaacc
     3361 acgtgttttt tactgatctt ggtcaatgta cgtattcatt ttgcagtttt cttgtttcta
     3421 taatagatcc tatcactgaa cgatctattt aatctatggt taataataga cggaactccc
     3481 tgtgtttgtc aaatggtttt gattttttgt tgtatgtttt atttactatt cttctttttc
     3541 aggtgtctct ttttcttttt cagacatgtc tttctctgac gtctttaata cgtgtgccca
     3601 agacttcatt tgattgatga actttttgct tttcaaatgg ataccgacat attcatcata
     3661 cagctggtcg atgagttcac ggattgcttg tttggtttct tctttcagat ggattccact
     3721 aattttatca taagaaatag ctgaaaacat ccgaacgaaa taaacagctc gaggatctgc
     3781 atgataacgg tgatcgtcca tcgaccaatg tctttcgcat atcacaccac catatttgga
     3841 agaatagtca aattttcctt ttgtttcccc gcatacgacg cagtgtgtcc agattggtgc
     3901 aattccgaag cgttgcagta tttggacttc aaaaatattc gtgatgattt ctgcatcgtc
     3961 tccttggtcc atccgttgca gtgcttgttg cgtaaactgg aacaaatgcg ggtcgtactg
     4021 atgatcttcg attgccgcat ctactagatt caataaatat gtgccatagc cgctcaaaaa
     4081 gatgtcttct tggatgtgtc gaaacgcatg gacatctttg acactgctta aaaatgacaa
     4141 accttcactt cgaaaattcc cgatataaac tgcttcagta aaagggagca aagccggagc
     4201 taagggctga ttttgccgat ggatctcttt gatataaaac atcattttgc cagaagattc
     4261 tgtaaagatt ttgactaatt tatctttttc tttgtaatta cggctagata aaatcaagcc
     4321 ttttgattct gcaagctggc tcatattctc cctcctaaaa aataaatctg gaaaagcaga
     4381 ttctgccgat ccagatcatt tatgttgcga tcttccgcag cttttctcaa cacgcggatt
     4441 tttattcagt ttatttctat acctaattta caagaagctc agaatatcag tattcgtctt
     4501 ttcggtagcc gaagtcttgc agatagactt ttttgtctcg ccagtctttt tgaactttga
     4561 cccaaagttc tagaaagact ttgtctccta aaagattttc gatatctttt cttgctttcg
     4621 ttcctacttg cttcagcatt tttccgcctt tgccgataat gatccctttt tggctatctc
     4681 tttcgacaat aatcgtagcc tggatatgga ttttatcatt ctcgtttcgc ttcatcgaat
     4741 caacaacgac tgcgacagaa tgaggcactt cgtctcgtgt taaaaacaag actttctcac
     4801 ggatcaattc agaaacgatg aagtattcag gatgatcagt cacttgatca tctggaaaat
     4861 attgtgggcc ctctggcatt tcactgacta atacatccat caaacgttcg acgttgtttc
     4921 cttctgtagc agagattgga atcacttgtg caaaaggcat ctgcgttgaa taatcttcga
     4981 tgattcccaa caactcgtct ggatggattt tgtcgatttt attgataatc agataaacag
     5041 gagaatgcac gttttttaga cgttcaataa taaaatcgtc tccccgaccg cgtttttgat
     5101 cagcactaat cataaataag accgcgtcca cttctttcaa cgcactgtaa gctgcttcta
     5161 ccataaaatc tcctaaacga tgctttggtt tatggattcc tggtgtatca ataaaaatca
     5221 actgagcttc tggtgtagtg tatactcctt ggattttatt tctagttgtc tgtgccttgt
     5281 cactcatgat ggcaattttt tgacccacga ttcgattcaa taatgtggat ttccctacat
     5341 ttgggcggcc gacgattgcg acaaaccctg atttatgttc tggcatatat gttctccttt
     5401 ttaattaaac aacaaatgat atattttagg gacaaataaa atcaacccaa cgatgacggt
     5461 aaaacaagcg gtcactaaaa ctgctccagc tgccatatct ttgatttttt tcccaatcgg
     5521 atgaaaatga aaatccgtaa acatgtccac gacattttca aaaacagtat tgatgatctc
     5581 tactatccat acgagaaaaa cagctaaaag cagccataac cattctatcc gatcaagttg
     5641 gaaaatcacg cccataaaca aagcgaggat tccgaacgca acatgtttcc tcatgttgcg
     5701 ttcttcctca aaaacagttt tgactccttg gacggcaaat tccacggaca tcaggaaatg
     5761 tttgtttttc tctacgtttt tatcttttaa gtccataggc atctaagatc tctttctgta
     5821 aaccaaacat ttctttctca tcctctggtg tcatatggtc atacccgttg atatgcaaga
     5881 atccatgaac cgctaaaaag ccaagttccc gatcatacga atggccgtaa gcttctgctt
     5941 gctctgcagc acgttcagta gagatcatga tgtctcccag tacacgaggc aatggattct
     6001 ctccatcttc aaaaatcact gggatttcgt cttcgccctc ttcttccaag gcaaaactga
     6061 tgacgtctgt cggtgcatct tttccacggt aatcacgatt gattacttgg attgctgcat
     6121 tgtccatgaa agtaacagac atttctgttt cttctggcaa ctctaaatat gatgctgcaa
     6181 attgcagcaa gtcgtcgatt tctttcattt tctcttctga gacttggttt gtttcatcca
     6241 tgaaggtaat atccattata catcgcttct ttctattctt cttgctattc ttcttgttct
     6301 tcttttatct tctcaacttc cgatttcatt ttaggatatt tgatccgaga atggaaggta
     6361 ctgcttaaac cgctgatcaa tgatttttct actttacgga tttcttttaa cgtcaatcca
     6421 ctgtcgtcca attgtccatc ggaaatacgc tcttcaataa gattatggac aaaactttcg
     6481 attttttcgc tcgttggatg gtccattgcc cgtactgccg cttcacaact gtcagctata
     6541 ttgacgattc ctgcttcacg gctttgaggt tttggtccag gataacggaa ttgctcttcc
     6601 gtaacttccg ggttgcgttc ctttgcctta acgtagaaat aacgcatcag cgtggttcca
     6661 tgatgctgtc tacaaatatc gatcaccatt tgcggcatat tataatcttc caatattttg
     6721 gcaccatctg tcacatgtcc aaagataata tgtttactgt cttctggcaa taagaaattg
     6781 tgcggatttt ccgctcctga aggcaagttc tcaacgaaaa agctggcgtg tttgatcttg
     6841 ccgatatcat gataatagca agctactcga gttagtaaag aacgtccacc gatttctgct
     6901 acagcattag cacttagatt ggctaccatc atgctatggt gatacgtacc tggtgcttct
     6961 tccagcaact gtttcaataa aggatgattg ggattgctga gttcatttaa tacgatcaca
     7021 ctatcatcat tgaccatcaa ttcaatatag gggtgcagac ctatcgtcag caagaatgaa
     7081 aacagtgcac ctgtgaatcc gcagactagc gttaaccaag tcgttgcatc cccaaagctc
     7141 attccttggt agataatcaa aatgacatcc atcatcacag gaaaaataat gacccacata
     7201 gcagcggata acccttgttc tgagatccgt ttgcgtctga cgatcgttgc catgagacca
     7261 gaaaatacat aggacatcaa aataactgtc agaaagttcg tgccaatcga atcataaaaa
     7321 atgaaaagtg cggatactgc ttgaaaaata ccagccatga tccctgctct tcgattcaag
     7381 aaaaagctta aaacaagtgg agcaaaagcc gcggggtaaa acagcggaat ataagcagct
     7441 tgttctgttt ggaagagttg gaaaaatttc attagtacga cgcttactga cattgccgtc
     7501 acgtagaaaa gtacgtattt tgttctttct cctgcatttt ggaattgaag tgaattataa
     7561 atcagtacac cgatttgaag caaaacagct aaaaccatgg caatgagtgg gaaaatagaa
     7621 gtcgtttgat tcgtcaatcc tagtaattcc aattttttca tcgctgaagc atcaatttga
     7681 tttccttcgc gaacaataat ttctccttgg aagatcatca ctggttgtac agcttctcgt
     7741 gcagattgtt ttaattcttc tgtctttttc tcattcaata catcattaac tacgatgcct
     7801 tgatccacta agtagcgaat catttgttgc tgctctgttg tgacattcaa atattgaatc
     7861 tgatcttctg cttcttgttt aaaagcttcc aattcgcttt cacgaacttg tttactcatc
     7921 tgttcgtcaa tgagcttcaa actttcatcc ctaactgtgt gaatttccgt ttcagtcatt
     7981 tcaaatatcg tcgaataaaa attgttcggc agtttttggt aaaacgcaac gttttctgca
     8041 ttcacgtttt caaaattttt cttcagtgta gcaatccgct cttctgtagt aggtttcggg
     8101 atattttcat cttccttcgc cttatctacc ttgccattat aagatttgtt gatggtatca
     8161 ttcgtcttat cgatcaattc gaataattgc ttgatccgat tgttctggtc atctgccaga
     8221 tctttttgat aagtatattc tggagtcact gcttctgctg ccagttttct tctttgttcg
     8281 gtttcttccg tgttctcaat cgttttattc gcacggatac tctcttctgc tacttggcct
     8341 tctctgaaat caatggcctt ttgtttgaca ctactaaatg taacgccgca gacaatgata
     8401 aaaaacaaga acagaaggaa aggcaatgct gcctttccga gtttttcttg tagtttctgc
     8461 agtgttttat tcaacatgtg cttatcctcc taagcaaagc ttattcttga tgaagatccg
     8521 ccttttcata agctttgatg atttcggcaa ctacagggtg ccgaacaacg tcacttgctt
     8581 caaaattaac aaaatcgatt tttttgattt gctttaatgt tcgttctgca tgaacaagac
     8641 cacttgtcgt cccacgaggc aagtctatct gacttgtatc cccattgaca atcatttttg
     8701 attgataacc gagacgggtc aagaacattt tcatctgagc gactgtcgtg ttttgtgctt
     8761 cgtccaagat aacgaatgca tcatccaatg tccgcccccg catgtaagct aaaggtgcga
     8821 tttcgatcac gcctcgttcc atcaatcggt tcgtatgatc caatccaaaa atttggtata
     8881 aagcatcata aacaggccgc agataaggat ccactttttc tttcagatcc ccgggtagaa
     8941 agcctaggtt ttcccctgcc tccacagcgg gccgcgtcaa aatgattttt tgcacttcgc
     9001 ctttttttag ggcagcaatt gctaatacta cggcaagaaa cgttttccct gttccggctg
     9061 gccctacacc aaatacgatg tcatgtttgg ctaccgattc aacgtatttc ttttgaccgc
     9121 tgttttttac ccgtataggt tttccattac ggtctttgac gatctcttcc tcatacatct
     9181 caacaaaata atctaatgta cctttttgcc ccattttcaa tgccgtcaca acatctggcg
     9241 tacttacgtg gattcctcgt ttgatcaatt cctgtaatgt ccgaatgact gaggcagcca
     9301 aggaaatctg ggattgctca ccaatgatct gaatgatttc tccacgtgta tggatggttg
     9361 tttccgttgt ttcctcgatc agttttatat gcttgtcgtg tgcacctaaa agcatgctga
     9421 catcatcagc agctgtcaat ctaatctcta aagaactaga ctcttccgtc aaaaatagac
     9481 atcccctttt tttcgattca ttctttccta ttttaccata ctcagaagaa actatatagc
     9541 aaataagaaa aggttgtaaa agagtcgctt aaccatacgt accaagaaac gttaaaaaat
     9601 agccgtttcc attcgctaaa ggtctcgttt tgataaaaag aagctgagaa tgtaagttat
     9661 atgaaagtgg agaacaaaat atttcgtttc attcaacaag tattctctag gtatttttcc
     9721 tgtttcaaaa aaagaaaaca aaatagttaa aatattcttg catttcaaaa aaaacaggtg
     9781 tattattacg tcaacaaata aacatacagc aaagcgtcga ggaaaacagt aggctattca
     9841 acgatttatt cccagtgagt catgtaagtg agaaatgaca ataaatcgaa tagacgaaca
     9901 tcatttccga gtcaatgtcg aaaacgtaga tcattgtggc tgcctccatt atcaggctag
     9961 cggataactt tatcaaaaag cgtccgtgaa tgaagaagct tttttaagcg aaaaaaggtg
    10021 gtaccgttct agaatctaga gcccttttcc caagtggaaa agggcttttt tttattttaa
    10081 ggtggtggtt ttcatggaat ctgatattag tggcattact aattgctgca acgtttatat
    10141 cgtcaatcaa aatgataatt attggaggaa aaatttatgg aagaaacaaa aacttattca
    10201 tggaaacaac tattgatggt cagttcactt atcttcggga tgttcttcgg gtcaggtaat
    10261 ctaatctttc ctgtccactt aggtcaaatg gctggcgcaa actgggtcag tgctggcgta
    10321 ggatttgcta tctcaggtgc tcttttccca ttactagcta tcttagctgt agtagtgaca
    10381 aaaagtgatg gtctgtatga cttagctaaa cctgtcggaa aatggtatgc tgccttgttc
    10441 ttaatccttg ttcatttgac gatcggacca tttttcggta caccacggac agctgctact
    10501 gcttttgaaa tggctgctaa accatttttg cctgaaaaat ataattcatt aggtatgttt
    10561 ttattctctg ctcttttctt tttacttgct tatttcctta ctgtccatcc aacacggttg
    10621 gtcaaatacg tcggaaagta tctaaactcc ttgtttcttg cattattagc aatcattttt
    10681 gtcgtttctt tattccatcc aatgggaaat ctaaatcaat ctgctgcaga tacttatcaa
    10741 acaaacgctt taacaaatgg tgtcctagaa ggttataaca cggttgatgc agtagctttg
    10801 cttgccttaa gtgtcacttt tgtccatgca gtccgtgacc ttggtttcaa agataaaaaa
    10861 gtcacagaat taacggcaaa agctggtagc ctgagcgttg cgctagaagt catgatctat
    10921 tttggacttg ttcttctcgg tgcgatgagt ttgaataaga tgtctttatc agaaaatggc
    10981 ggaactgcac tttctcagat cactaatttt tatttaggta acttcggcgc tagcttctta
    11041 ggagtgatgg tcacattagg tgtcttcact accgctatgg gactcgttgt ttcttttgcg
    11101 caagatttcc ataaactgtt ccctaaagtc agttatatga catggctgcg gttaacgact
    11161 ttcgtctctt ttgtcgttgc aaatgctggt ttagacaata tcatccaatg gtctttacca
    11221 gtattgatgc ttttgtatcc attgtcgctt gcgttgatct tgctttcctt aacagcaaaa
    11281 tttttccaaa agacaccatt tgtctatcaa gtaacgatgt tgtttgctgc tgttcctgcc
    11341 gtattggata tgctggcaaa ttcgcctgct ttagtgagtc aacaaagagt tgtagcaagc
    11401 atgctcgaat tttatcatca tcacgttcct tttgctgcat taggacttgg ctggatggtc
    11461 ccaacgttac ttggttacgc tggcagccta ctgttttatt acgcctatcg cctatcaggg
    11521 tataaacaag aagcaaatga actaccagaa gaataaccaa atcaaacaca atttaacata
    11581 agaaatatta aacaggaaaa aaccagctag atgaaagaat cctattcttt cgtctagcta
    11641 ttttttagtt ctctttttta cgcgcacaaa aaaactgcgg acaatgattg tccgcagttt
    11701 aaatgggctc tataatatct agtgttggtg acgccttctg ttgccaatac tttttctttt
    11761 ttctaataaa cgcaaacaga caccttgaaa tcctttagaa taaagtcgac gaaaaccatt
    11821 caaaggagtg tttcaagatg tcctattcag agtttaccaa agagttacta gatattctag
    11881 acctaaatct tatctttcat gaagatgcct ttcgcaaaga gcgaatcaat gacgaaacat
    11941 gttttgtttt tgatggcaca ttgacctatc aaccagagga atgcttccat tgtcactatc
    12001 aaaataagca aacgatcatt aaat
//
LOCUS       DAZKCH010000081        11778 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000081 DAZKCH010000000
VERSION     DAZKCH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.082"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2563)
                     /locus_tag="ACG84X_002292"
     CDS             complement(<1..2563)
                     /locus_tag="ACG84X_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFP9128124.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSI"
     gene            complement(2785..3669)
                     /locus_tag="ACG84X_002293"
     CDS             complement(2785..3669)
                     /locus_tag="ACG84X_002293"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFP9128125.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3764..4201)
                     /locus_tag="ACG84X_002294"
     CDS             complement(3764..4201)
                     /locus_tag="ACG84X_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128126.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4418..5329)
                     /locus_tag="ACG84X_002295"
     CDS             complement(4418..5329)
                     /locus_tag="ACG84X_002295"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9128127.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(5706..6344)
                     /locus_tag="ACG84X_002296"
     CDS             complement(5706..6344)
                     /locus_tag="ACG84X_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128128.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6348..8330)
                     /locus_tag="ACG84X_002297"
                     /pseudo
     CDS             complement(6348..8330)
                     /locus_tag="ACG84X_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
     gene            8510..9175
                     /locus_tag="ACG84X_002298"
     CDS             8510..9175
                     /locus_tag="ACG84X_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128129.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9572..11605)
                     /gene="brxL"
                     /locus_tag="ACG84X_002299"
     CDS             complement(9572..11605)
                     /gene="brxL"
                     /locus_tag="ACG84X_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HFP9128130.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
BASE COUNT         3620 a         2403 c         1823 g         3932 t
ORIGIN      
        1 ggatagaaag aacaaattta cctgtatcat caatagttgt ttcggacaaa acagcttgat
       61 tttttttcaa tgaaaccaaa gctcctgctt cgcctgtacc tgtgattgag cgagaagctg
      121 cattgatcaa tgtggtactt aatttagcag gctcaggagg aatcacatcg actgtcgttt
      181 tggcagagtc cagttctgtc acttcttggc cgcctcttac ttttttagca gcaactattt
      241 gcacttgatc ccccgttgtt agtctttctt cgttgggtac ttgaacctca aacaaaccgc
      301 cttgttcgcc ttctccccac ggattatatc ctgtcccttc attttcatct gtttgtcctt
      361 gtgtgagagc agtaatttct acaggtgatt tcgtcgtatc tgcataagta atacgtaaag
      421 tcacttctac ttcgcctgtc caagcatctc ttggctttgc ctcgacacct tcgggaacaa
      481 cgacatgccc atagattttt ttatctgcat tcgttggtac tcttaaggat tcaatcatcg
      541 gaagctggtt attggcactg attcgattat aatttttcat tccggcacct gtctgagcaa
      601 attcatttgt taaacctgca ctagggcttg atacaaaatt acctaagtcg gttccattga
      661 tcgataagtc tgtcatatca gaaaaataat ccggatcttt ttcaaagtta tcgaacgtta
      721 ctcctgcctt tcgccataaa gcaatttctg aatgagcgat cttcaaagaa gaatcgccat
      781 ttccttgaaa tacccagcca cctatgccat tagtctcgct tccgatccgt ttgttttgga
      841 aatcgaaata ggtaggagat tctaagtcta cattcaacac atccccactg atgatgccag
      901 tcttatcttc cccagttttc ccgaccatga ctaaataagt tttttcgcca gccataaagt
      961 tcaaatcaat atctccagtt gtatctacgg tagctccgga atctgcgcgt atatcgatat
     1021 ttgatttttc tccagtaacc gtaaaatcag ctgaccctgg actttctaga aaaccagaag
     1081 cgtcataaaa ttggatcgct tggtttcctt gattgagtct gttcacataa gatttgccat
     1141 cccctgcatt tcttaccttc aatgagcctc cattagttac tgttagtttt tgcgtaccgt
     1201 tctcaaaacg aactgcgcta gaacgaccac tttgcttatc aatatcgatg actgatccgg
     1261 ctccttctac gatcaaagaa agtcctttcc ctacaaaacg catcccattg tttccaggtt
     1321 ggtcgccatc tccagccatt ttgaccgaga tttgtccacc acttgataca tggatttgac
     1381 tagaatctcc ttgcaggcga aatccgccag tagtcgctgt attgattgtg attttcccat
     1441 cattcgacac agcgactctt gatcctgagc ctctcatttg gataattccg cgattgttgt
     1501 cgttggtaat attgatcttt gtatttaccg aaaattcact tcctgagcca ctgactttaa
     1561 atgtgacatt cccgggtagc gtatcgacag cctctccttc atcgctgacg ccatctgccc
     1621 gatcatagtc aagagagacc tttgaaccac tcaagatatg gagtcctggt gctgtttttc
     1681 cactgcccgt ctcatcacct gaatctagaa aaccatagaa ttttcctaga tatggtccat
     1741 aaagctgact accattgatt acatttagct gatagcttct acaaaaataa gctttacccg
     1801 gagcggcatt catcccttct ttcactggtt ggacatccaa tacaccggaa acaccatcta
     1861 atgtgacagt tgcacgaggg gcgtaaatca ggcctaattt agaaccatca tataagtcaa
     1921 gtgtcccggt aaattttatt tctcccgtaa aatgatatct gtttccccaa aaatcggaca
     1981 tataagcaat gataatggca tttccatcga tatttggtat caacccacct ggatgagctg
     2041 ccgttccttt aaaattctga aactcgatcg actgaggtgt ctcattgata tagatgtgat
     2101 gtgtgccgaa attatgagca agtccgccaa aatcgataac gatatctcgc ttgatctcca
     2161 attccctgtc taaagtcaaa ggctgagtta aacgaatctt agctactgat tcgtctgcga
     2221 gaagctgcgt cagttcttct gttgtggcag cttcgctgta cccatccgct gaaacaactc
     2281 taacctgtac ctcttcactg ctatcagacg tttgttcagc tacttctgag gtctcacttg
     2341 tcttattttc ttcttgcctt gtattagaag taggcgcctc actttgggat tctgtagttt
     2401 cagaagtaat tgattcttct gaaaaagtag tcttgtcaaa actttgattc tctgattgcg
     2461 ttgattcgct tgttttctct acatcggcaa aaacggatgt caccatcaag agagggaaga
     2521 caaacaaaat cgacgcaatc agctttttta catattgatt cattctccac catcctctct
     2581 gacgttttga caattttatt ttaacgtttt aatttatttg taattgtact ttcatattta
     2641 aaatatgtat ttttatggca aatttttctg ttaggtgaaa atttcttttt tgtacaaaaa
     2701 aaggctgtga caaaagtctt gtcacagtcc cttattccga acaaccgatg tcctcctgac
     2761 aactcttcgg tcacaacctc cattttaaca ataaacctgt aaatgtgagg gtaacacttt
     2821 gattgtcaca ggtaatttat ccccttcatc tccatcaaca ttcgtcgtca attcttcctc
     2881 atcagctaat gacacaacta attgctcaca agtaagatag gctagatttt tcgtagattc
     2941 atctactcct tttaataggt ctggcaatgt tttaagcgta tcgatcaaag aagaatcttt
     3001 taaataaacc aaatggagct taccatcatc cacttttgca tttggaagta atgtttcaaa
     3061 accgcctact gagttagtta gtcctatcag caagatactg ctctcaattt cttccttctt
     3121 tccatcaact tctacgtgaa acgagtagga ttgtgtggaa gctaactgtt tgattcctga
     3181 catgaaataa gctagttttc caaatttcgt cttcttctcc gcatctacat cattgattgc
     3241 ttcagggata gagccaattg cgacgacatt cataaaatag tcgtcattta tttttccaat
     3301 atccaatggc ttgactgatt caatcgaaaa atgattgatc gcttcctcag gttctagcgg
     3361 tatccctaat gctcgagcca agtcattcac cgtacccaat gggaaaaatc cgaaatttgg
     3421 ccgatgttct tgttcagcga ttccactgat tccttcgttg actgttccat ctccgcccat
     3481 gacaaacaca ctatgatacc cttccgtagc cgcttcgcga gtaaagtttt ttgcatcccc
     3541 tgcttttttt gtatgcaaga cgaccacttc atcaaacacc gattccaatt ttgctatcgc
     3601 taattgctca aattcctttg cttgttcacc gcctgaactg gggtttacca ctaataaaac
     3661 ttttttcatc actttctttc ccttctgatt gatttcttta atataacgat agcataaaga
     3721 aaaaaattag gctgtgatga agtactgttc atgaaacatt catttatttt ttgacaagat
     3781 aaaataccca tactatgaaa ctgaggaaaa ttaaaacaat gatataggaa ataaaagaaa
     3841 atgataggca ttgtatacct aataaagtaa aaatcttagg tggcagataa aaacacaaaa
     3901 atagcaagag aatgtaatag cgtttcttcc actttttgtt atcagacctt atagcgatca
     3961 gaggaatacc aaatgcataa ctgaaaaact cttgatgtac tgttaatatg tcacgacctt
     4021 gaataataaa tgcaacaatc cccgctataa ttagtgtgcc taataccaaa acggaaaatt
     4081 gatgaatata ttttatatac aaatgatcca ttgtacttcc tgccttttta tttgtgagaa
     4141 aaacaaatcc gtatacgtga ataacttcta gaaataaaag aaatttgcaa aaccactcca
     4201 tttatctact tctacgtgca ttttttaata tcgttttctt tatttaagat tatacagaaa
     4261 aatatctagg gtggctggat tctaagtaaa aaaaattttt aaaataaaaa gaactaaatc
     4321 aagtaataat taaactactg ttgatttagt tctaataaaa agatttagat gaacagtttt
     4381 attgatttaa atagttcata ttttttattt ataccgctta tttactactt gctgtactag
     4441 aatctgaagt gaatgtactc aaaacatttt caaagtcttt gtctttgatt tttacattag
     4501 cgtctttcaa tacttcgcca attactttat tctggaaggt actgtcactt aattttgtgt
     4561 ctgttgcaat ttctttcaat tcttttttgt atttatccat gtcgttgcct ttgttttggt
     4621 ttttcaccat tttaaccaca taatattccg tagtataagt tgaagcattg gtagaagtga
     4681 tcacatcaga aacttgacca tctttcaact taaaggctgc ttctttgact tctgccggaa
     4741 ccgttgtagt agtggaatca aatttcactt ttccgccatc ttcttttgtc gtagtatcag
     4801 ttgacttgtc tttggctaat ttagagaaat cgtctccctt atcagcagct ttcttcacat
     4861 cttttgcatc atcttcactt gctacttgga taatttgagc ttccacttct ggatggaaag
     4921 attcccaagc cgtttttaaa tcttcatcgg tcaatttgat atgtttcttt agaccttctt
     4981 gaaaggctag actttgtttg atactgtctt tgaatgtttg ttctgtgtaa cctgcagatt
     5041 tcaattgtga atcaaatgaa tcacccaatt gtttctttgt ttgatcatat tgggaatcga
     5101 tttctttggt tgatacgtca tctccatatt tatcttcaaa tacttgataa acgatcaact
     5161 gttgcacagc ggaatctgct ccttgcattt ttttcaagct atccattact tcttgttcgc
     5221 tgattgtacc gcctttataa ctaacggctg ttttttcacc ggcattcgta cagcctgaca
     5281 ataagccagt gcctagtacg atggcaagtg ctaaaaatct ttttttcatt tatcaattct
     5341 cctacttttc gttttttgcg aattgctaaa aacaaaggtg ttcaagatga aaatcatcaa
     5401 gaacaccttt actaatctgc tcgatacgtc ctgaatagat ataaggctac acaatccaga
     5461 aagttcgctc agcagaataa atgtcaagta gcacatcaca ccttaatata ctacttcttt
     5521 tgttaccgtt tttcaagtct atcttgcgtt ccgtatttaa cgtaactaat tcttagaaca
     5581 aatgttatcg attttgtttt tcttcttccg ctgttgggat attcaaatca gacactttta
     5641 tgttcgattt tccagacatt tttttgttgt ttttattaga aaaagtttgt tttttcattt
     5701 gttttctaaa gcatgatctt cttgtttcct attttggtca gatatggatc atgcgtgacc
     5761 acgataacta acgtaccttg ggaagcctgt tgcgataaga tttcaacgac ttgctcctta
     5821 tttcgtttat ctaatgatcc agttggttca tcggctaaaa tgattttgct attcttcaat
     5881 aagactctcg cacaggcgat tctttgcttc tcaccaccag ataatgtgta gataggcgta
     5941 cttagcttct tgtttatatt tacttttttc aatgcctcat actttgctgt tcgcttatct
     6001 gaaacattta aattcgaaaa cttcaatcca atatctaaat taaaatcgat tgtttcatat
     6061 tcaatcaacc caaaatcttg aaaaagaaaa gagagggcat ttctttttat caagcgcttc
     6121 tctcttccag ttaaatgttt tgtttcttga ttaaataaat aaaattgccc tgaactgaat
     6181 tgatcattca atcctaatat attcaataaa gtacttttcc ctgctccgct ctctccaact
     6241 acagtcacaa aatccccagc atccgcagtg aaacgatcca aatgaagaat cgttttgttt
     6301 cgaatgattt ttttcgcacc ttttatcact atcaacggct ccaattgtta acctccattc
     6361 atcagcaata actgactttt cttttctgta gacaaaataa aaacaactga aagaataaaa
     6421 tcaatgaagc taaagaaaaa aatattaaaa agatatttag gctctctttc tataagaaaa
     6481 aggaagatta cacttgtcgt tccccatttg atgaggttca tcatgaagaa atctttatac
     6541 gtttcaaaga gcgaataacc acttgaacga aagatagcga ttttccgaca attgtagaca
     6601 aaatatatgc ataacatgac atagctcaac aagaagaaag aaaagaaagt gagtaaaaat
     6661 atctgtatca agtaatgaaa tgatctgctt aacactttga cagctatctc ttcagtctga
     6721 gtatacggaa atgataactg caagttatca cgtaactgac tttcttcaat cagctcaaat
     6781 aacctttctt tcgacaaaga gcctatcttg atctttaacg gtggatagat ttctccgctg
     6841 agaatatttc tttcccaata cgtactgttt ttcaatgtca gtatttcaac aaccggataa
     6901 tgttcgatcc aggggataga aggaataaat gtataaatgg gttgattgtt ttttataaat
     6961 agaaatttcg gttctttttc actgatttct tgataatatt ctgttatttg cgccaggtca
     7021 ttttttaaat ctgtatgtct atatcgttca gggatcaata taacagggtg cgtttctttt
     7081 tcggttattt ggatcaacct tccagagaca tcaatcaaag gaaatttctt aagataattc
     7141 agatttattt ttatccctct gccaaactgt tcattttctt cattcaagta atctgataca
     7201 ttgactaata tacttccgtt tttattcaaa gtttcatata attcctgatc ggctgctgat
     7261 gcaaaacgat tggaataaat aaaatccacg tggtttttcc cgatggttac tggataaaat
     7321 acatgatagt cctcaccagc gatttctttt ggtgtttcat gggaaacagc taactgtgaa
     7381 gaagaaaaaa cgatagttgc taattcgaca ttggcaacgg tcaaaagaag agaaaacaac
     7441 aatccaaatg taaaaagaat gtattggata tagttgaacg cttctcttaa cgaagcgatt
     7501 ttttcaacta ataaaagaga aatcaaagag ataccctata ttccgctgaa caagaaaacg
     7561 tacatctgga acaaataaag aaattgctcc ttataataca taaaaataaa accaccaatg
     7621 attcctgcaa ttatgaatgt aataatgatt ttctttttcc ccaataaaca ccacaatact
     7681 tgatgtaatg aaaagccatt attcaacaat aaactgattt ctttattcat caataagaaa
     7741 aaggatgata acaaaaggaa taaaagaatc aatccaatag ttaaatacac tcgataatta
     7801 tatacgtctg tacttgaaat aaccgaatac gaatagctat tttcaaagtc ttcaaaaata
     7861 ttagtggcat aatcagtgtg aaatgcttga ttgaatcgtt ccacaaatag taaaatgaac
     7921 cgttcatagg cttctttttc tctcgtcatc aagaaaaatt caccttcaaa atcttttatt
     7981 ttgatcgatt cttcaatgga cgttacgcga aaggaggtat tagaataggg taccttctcg
     8041 tgagaagatt tgacatcccc ttgataatac aatgtcattt caagctttgg ctgtatcttg
     8101 aagttccaag atgtatctac ttcattggat tcatttactg tttttttcat ataagaaagc
     8161 tcagtttctg atgagacatt ttcaaatacc atgattagct gctcatattc ttcttgccca
     8221 ataaaatgtt gtggcaatcg aatcggagta taagtatctg tttgatggaa aaattcattt
     8281 gtccgataga gtacctgttt atttataata accaaggcaa aaccactcat gataccggtc
     8341 actatgattg tgagtaaaac tgtgaacttt tttttgatta tcaccactct cccttactta
     8401 aatgattctt tgataaaatc ataccgtttt tcatcaaaaa aacgtatcta tcaaatgtat
     8461 aggtcatgta gaataaatct atatactgta gaatcgaaag gagaagaaga tgaacatcgg
     8521 agaaaaaata cgaacttacc gcagaaattg taagcttacg caaaaagaat taggcgaaaa
     8581 aatcggtgtt tccgataaaa caatctctag ttgggaaaat tctcgtacaa tgccagacct
     8641 tgaaatgctg tcacttttac atcagacttt aggtctgccg attgattttc cttctattga
     8701 atcagctacc gaatcaatag aaccaacatt gccggatgaa cctcttgtta tcaagaaatc
     8761 ttattcatca aaacaaccct tctcactcaa aaagacacta tctttctttc tgctcgtctt
     8821 ttgtttggtc tatctttttc ttatcaatta tcaatataaa aatgaaacgg ttgatcgatt
     8881 caatcctttt ttgaaaccac aaatcggcta taccacactc cctgtaggat acgtggaaaa
     8941 ttccatcgaa cattgggtat gtaatgatat ctttgttcat ggtacatggc tgtcttttca
     9001 cgctggagag gtagaaaaag gtaagaatca tgctgtaatc aaacacaaag gaaaacacgt
     9061 catgaacgtt cgcctgctca cttgggaagc cattccctca gattaccaag aaatcctcat
     9121 ccaagactat gacgatgcct taaaaagaag ccctcaggag ccagataggc attaagtagg
     9181 agatgaacgt agagatagaa aaaatcaatg cacatgatct tatcaaaaaa aaacaggggt
     9241 acaaattaat tgaaaaagct ttgagatgaa agttcctaaa taaaaaagtt cagaatgata
     9301 ggtaaaaaaa tgactaacta ttctagtatt aggctatttg tattattctt ctgttatttt
     9361 tatatcaaaa aatccagaaa taactaaata taggtatttc tggcttatag tataatattt
     9421 acgccacagc ccccaatgat tctttttgga atcatgatca aggacggaca tacacaaaaa
     9481 tattttgccc attcgatccg aatagattaa cgactaatct agtaagtaat atagattggt
     9541 acgtagtcaa accagcaaat ggaaaagttg tctattccac cccaagggct ttaaagacag
     9601 catcttccgg cgtttgataa aaaatcaaat taaaggtacc cattaattct gggggtacag
     9661 ttccaatatc agcagcgctt atcataggta caagtacttt tttcgctccg gcatcttttg
     9721 ctacttgtaa acagttagct aaattatcta ccttaatcat agaaccacca attgtaatat
     9781 cccctaaaat aactaaactt ggtaatacag gtttatttaa ggaaactgag cataaagcta
     9841 ttatagttga taacgataat gtttttgtca taccaatgcc attcatatct tgaacatgaa
     9901 cgacaaaatc ttttgtcgtc aaactaatag actgactaac acttccataa ttagctctta
     9961 aatatcggta tgccgaatcc atcgcttctc ttgctccagc atctgaattg atcccagtac
    10021 gttcaaactt tccatttccc gaagtcattt gcgtttccaa tttataggta cctaattgcc
    10081 cagttttgcc ataagatacc gtgtacaaat gccctggctt ccctaaccct tctggaatca
    10141 aagttcctcc accttgttca ggaacagaaa catactcttc tcgctcttct tctaaatcaa
    10201 tgtatgaaaa attgacatca taaaattcca ttccaccaat tttctttaat tgttctttta
    10261 cacgacgacg catttcaaga gcaaatctta gtatttcttc gacatcactt ttttcaaatc
    10321 taccatcagg atacaacagt ttcatcatcc cagatacaat ccgacgaact gcaatcgtat
    10381 cccgctgatt taattgagaa ccaagtttga aatatttatc aaaactatcg ccaaaactaa
    10441 cttttcgaag ctcacgcatg acttcagaaa aataatctgt aatgaagcca tagtcatttg
    10501 taaaaaaatc tggtcgatat ttaggaattt cccaacctgg taaataacaa tgcatccgat
    10561 ccaaaaaggc tgaatccgtc cccataacct ccggaaatgg ctcaaataaa ttcgaagttt
    10621 tcaatattac atcaacgctt tgattaatat ttcctacaaa agccattgat gctgaagcat
    10681 tcttttcttc tttgcctcta gcaaaagatc ctgaagccat gtaatctttc atgatttgaa
    10741 cgccatcatt atccttaaat ttaatcccag caacttcgtc aaaagcaaca cagtcccaca
    10801 tacctacaag tcccattgta cgactagcca tattatagaa aaggtttgct actgttgttt
    10861 gtccacctga aacaaggatt gagtttggtg aaatttcttt atatacatgc gatttacctg
    10921 taccacgtgg tcctagttca cagagattaa aattattttc aattaatgga ataagtcttg
    10981 ctaaatgaag ccattttacc cttttattaa attgtgtagg ttccatacca atggaccgta
    11041 gaagtaagtc aatccattca tttgtagtaa actccttgcg agccatcttg taagcctcaa
    11101 tgtctaaacc aggcatttgg attggatcaa ccttttttgc aataaaaggg ctattccaac
    11161 gatcattctc atcataccaa tattccatcg aaacaataca ccagatcccc ccacctaata
    11221 atcgatcaaa ttttttcgga tactcttcac taatttgaac attttttaat cccaggttag
    11281 agaattctgc ttcataacaa tctttctttt catttaaatg tacagttact ttatcaataa
    11341 ctgtataacc acccaattca cgaatttttg cttttacttt ttctgcttca tcaggacgca
    11401 catagtttcg agcaagaata tttttaacat tttccacacc tttttcaacc aatgtttcat
    11461 ccaatgacga agcatacata ccaagtaaat attccaatac ataaacaggt acattcgcac
    11521 cttctttaat tttctttgtt aaatcttttc tgacaatctt tccgggaaag aattcagata
    11581 actttaaaat ttcctgttgt tccactagaa ttcctccatg tgttcagtca ttataatagc
    11641 aattaaagta tatcatactt aaccagtagg cttgataata caaaagaaaa agtatccaca
    11701 aaaaattgtg gatacctcgt ttttatatat caaaatcaaa tgattctgca aaaggattat
    11761 ctataatgaa ttttattc
//
LOCUS       DAZKCH010000082        11587 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000082 DAZKCH010000000
VERSION     DAZKCH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.083"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..305
                     /locus_tag="ACG84X_002300"
     CDS             6..305
                     /locus_tag="ACG84X_002300"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9128131.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACG84X_002301"
     CDS             378..1739
                     /locus_tag="ACG84X_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFP9128132.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACG84X_002302"
     CDS             1761..2021
                     /locus_tag="ACG84X_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128133.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACG84X_002303"
     CDS             2035..2787
                     /locus_tag="ACG84X_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFP9128134.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACG84X_002304"
     CDS             complement(2881..3486)
                     /locus_tag="ACG84X_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9128135.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACG84X_002305"
     CDS             complement(3539..4513)
                     /locus_tag="ACG84X_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFP9128136.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACG84X_002306"
     CDS             complement(4891..5610)
                     /locus_tag="ACG84X_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9128137.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACG84X_002307"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACG84X_002307"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFP9128138.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACG84X_002308"
     CDS             7161..8558
                     /locus_tag="ACG84X_002308"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9128139.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACG84X_002309"
     CDS             8639..9079
                     /locus_tag="ACG84X_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFP9128140.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACG84X_002310"
     CDS             9227..9553
                     /locus_tag="ACG84X_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFP9128141.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACG84X_002311"
     CDS             9554..10303
                     /locus_tag="ACG84X_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFP9128142.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACG84X_002312"
     CDS             complement(10383..10838)
                     /locus_tag="ACG84X_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFP9128143.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="ACG84X_002313"
     CDS             complement(11265..11540)
                     /locus_tag="ACG84X_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128144.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT         3655 a         2013 c         2354 g         3565 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctt
//
LOCUS       DAZKCH010000083        11558 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000083 DAZKCH010000000
VERSION     DAZKCH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.084"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(366..1484)
                     /locus_tag="ACG84X_002314"
     CDS             complement(366..1484)
                     /locus_tag="ACG84X_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128145.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1717..1839
                     /locus_tag="ACG84X_002315"
     CDS             1717..1839
                     /locus_tag="ACG84X_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128146.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            1955..3262
                     /locus_tag="ACG84X_002316"
     CDS             1955..3262
                     /locus_tag="ACG84X_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFP9128147.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3381..4580
                     /locus_tag="ACG84X_002317"
     CDS             3381..4580
                     /locus_tag="ACG84X_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFP9128148.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4607..5875)
                     /locus_tag="ACG84X_002318"
     CDS             complement(4607..5875)
                     /locus_tag="ACG84X_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFP9128149.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(5930..5996)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(6038..6684)
                     /locus_tag="ACG84X_002319"
                     /pseudo
     CDS             complement(6038..6684)
                     /locus_tag="ACG84X_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7092..7595)
                     /locus_tag="ACG84X_002320"
     CDS             complement(7092..7595)
                     /locus_tag="ACG84X_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFP9128150.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7718..8482)
                     /locus_tag="ACG84X_002321"
     CDS             complement(7718..8482)
                     /locus_tag="ACG84X_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFP9128151.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVISLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8590..8865
                     /locus_tag="ACG84X_002322"
     CDS             8590..8865
                     /locus_tag="ACG84X_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFP9128152.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9303..10253
                     /gene="yidC"
                     /locus_tag="ACG84X_002323"
     CDS             9303..10253
                     /gene="yidC"
                     /locus_tag="ACG84X_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFP9128153.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     IDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(10432..10611)
                     /locus_tag="ACG84X_002324"
                     /pseudo
     CDS             complement(10432..10611)
                     /locus_tag="ACG84X_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11437..>11558
                     /locus_tag="ACG84X_002325"
     CDS             11437..>11558
                     /locus_tag="ACG84X_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128154.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNV"
BASE COUNT         3493 a         2423 c         2037 g         3605 t
ORIGIN      
        1 tttaaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttca caaaaatttg
       61 agaaataatt tttgtcaatc tcttcttatt tcttgaagct gaccacttct gtcacaacct
      121 cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccacca aacaaaaaat
      181 atgaagagct atttttgctt gctgttctta ttacttgatg cagaacagct ttttcacaac
      241 ctctcataca cggtgtttaa tcagctgacc ttcggtatta gctcaaaaaa cggaaaaata
      301 tgtgaaacta tttttccgtt tgtttctcta atactcaggt caaaacactg atttcacaac
      361 ctcttttaat aacgaagaat cgctgtcaga ctcttttcat ctggcgcatc tttttgatcc
      421 aaaataaaca ctttcccgcc attaatgatc acatcatctg ctaatgcatt cagcacttga
      481 cgccgatcat attctgtttc aggatcttca ccgaaaccat cagctaagtt tgacgtagcg
      541 ataaataaat gtgacacttt tccttctttc gcagctggaa cgatatcaac taactgatcg
      601 atgaatttct tatctaagag tttattgtat tcttttgatt cttgagctgc gagttcactt
      661 gacagcttct tcgccccttc ttcgatatct ctaaaggata gctgcgcagg agaagcagaa
      721 atcgcaacgt ctgcacaata atagggattt ttagcaattt ttttgaacat cgtctgattt
      781 tctggtaatg caaataaata aatcggccat tgttcaggat tttcgaaaga atccttcaag
      841 tacgtatcaa cagcttggta atagttgacc caatcgatct ctacttcttc atcttttgga
      901 tttacgccat ggaaagttac tccatctcgg gctccgcctc ctccattaga agagaagttc
      961 aaaccgccac ctgtcagttc agatcccaat gcagtaacga catcaaccgg tgccccttct
     1021 ggtagagata cttcttttac ttgtttgttg ctgacctcat acaatttcat ggagtcgcgg
     1081 ttcaatccca ataaataata agaatagttg aactgcccat ttttgataat agccagtaaa
     1141 taaggaagat cacttacata gtattgatcg tctaccggga tactcaaacg atggatatag
     1201 gtctggtcag cagttataat gaccgctaca ctcgtagttg cactacgcca aaacgaagga
     1261 tctcctaaca aattttcaat tttttcttgg aacggggacc agtcatgttc ggaatatttt
     1321 ttctcaaaac gtttctttgc ttctttcgca aaatttttga atttgatctg atctttttcc
     1381 acatcttgat gggcgacatg cgtattcagc atgatcgtga cgaatggtcc tttagcgcct
     1441 tctgaagtca attgtgtcaa taattcttta tccttttttg ccataaacgt acccctccta
     1501 aaaaaatcat tcctttgttt ctatctaaag tctaccacaa cactattttt ccatacaata
     1561 aaacgtatct aaaaaaataa aacggtttct acggttttaa atttagctat ttttttaagt
     1621 tatcttcata atttcctcaa ttatttagcc ccagtcttca actattcttc atgaaatgct
     1681 gataaactaa gaaaaagaat aaaagaggtg gatcttatgc atttgattat gattttcagt
     1741 ttattaagta ttatcagttt atttgctttc agcgcttccc gcttattaga tgcggaaaca
     1801 cagcctattc ctgtaaaagt acgtaaaaac gaccgctaaa cttccataac gcgcgttctt
     1861 atcctaaagt tttttcagaa acattgaaac tctctcccct ctctgataaa attttaattt
     1921 gtagcgaaac aaattaatta caaggagatc ggatatgtcc ataaaaaaaa cacgtctagt
     1981 cctattattg gctagtctca ttctttgcct tgcttctttt ctaccagctg ttgctgtgca
     2041 agctgaagat acgttcaaag taaatgcaaa agcagctttt gctgtagatg cgcaaagcgg
     2101 taagattctt tatgatcaag atggagaaaa aaccatgggg atcgcttcaa tcacaaaaat
     2161 catcggtctt tacatcgtcc ttgatcaagt aaaagaagga aaactgtcat ggggtgataa
     2221 agtttcgatt tcagattatg cagaaaattt gagtatcacc ccagatttat cgaatgttcc
     2281 tttgcataaa gaaaacacct acactgtcaa agaattattc gactctgcaa tcatccagtc
     2341 agccaatgct tcaatggtgg ccttggcaga aaaaatctct ggcagcgaag ctaaattcac
     2401 tgaacgaatg aaagaacaat tgaaagattg gggaatcaaa gatgcaacaa tcgttaatgc
     2461 atcaggattg aacaactctt atcttggcga aaaccgacca gaaggcactg gagaaaacga
     2521 cgaaaatcaa atgtctgctc aagatgtggc catcgttgcc cgccatttga tcttggattt
     2581 cccagaaata ctggatgtat caagtactac gacccaaatg tttggcgaaa atacgcaatc
     2641 accagtggaa atggtcaact ggaactggat gctcccagga ttcgttaatt acaaggaagg
     2701 cgtggacgga ttaaaaactg gtacgactga gcttgcaggt gcttgtttcg ttggtacgat
     2761 cactaaaaac gatcaacgga tcatcactgt cgtattgaat gcggacggcc atgcggaaaa
     2821 cccgagtgcc cgcttcaatg aaacagaccg tttgatggac tactgctatg acaattggtc
     2881 agaaaaagag ctcggaaaag ctaacgcaag tattcctagt ctaaaaacca ttgatgtaaa
     2941 agacggaaaa gaatcaacag ttcctgttgt gcttaaaagc cctgtaaaag tatgggtacg
     3001 aaacgatatg gatactggca aattaacgat cacgccaaca cttgacaaga agcaagtcac
     3061 tgacaatgag atccaagcac ctatggataa aggtacaaaa atcggtaccg ctacgatcac
     3121 cttggcagac gataaattag gctatttaga agacaacaat gcaccatcaa cagagatcat
     3181 tacggataaa acagtggaaa aagcgaatat attcgtgatt ggctggcgac gcgtcgcaga
     3241 atttttcggc aacttgtttt aattgaacaa taagaaaaac atctttccat cggaaagatg
     3301 tttttttgct ttttctagtt taaataacag cttttttcat ctattttcgt tatactgtat
     3361 aagaaaaagg agttgaattt atgaatctaa ccagagatct gatcttttta gttctctatc
     3421 ttattggggt attctctatc gtttattggc gaaaacagaa gaaggatcct tccttgttct
     3481 tttacggcag tacgtggaca tttacggtaa tcttaactta ttttgtcgtg ttggaaattt
     3541 tttattcgac cttttatttt ttgattccat tgttgttctt tagtatcttt gctttttctt
     3601 atttcacaga aaaacgaagg ctactgaatg gtcttttatt caatgtttta ctcatcagtt
     3661 tcggcatcta cttgtttgtc ttgctgtatg aaacgcaaaa tatttttctt ggcggactga
     3721 tcgccttgat cacgattcca ttgctacttg tccttttatt tggtatttat ggattgattg
     3781 tttttctttt ttggaacggg gtcacagttt tacgtagaga atcgcattca ttagctaatc
     3841 ttttaacgtt gatactagcc atttttctta cactgtttct tgtttttgac tttttcttgt
     3901 taaaatattt gccgcaatgg ataaatgctt tgtttttctg cgttcccctg atcttgatct
     3961 atctatttat cgtattctac aactttttga ctgtctcatt cttgtatcag ttcaaccggc
     4021 ctcgatacaa tcaagacttc atcgttgtgt taggcgctgg attgatcaat ggagaaacag
     4081 tttctcctct tctagccaag cgaatcaata aggcaattgc tttttatcgg gctcaaagcc
     4141 gtgctacatt aaatccgccc atcttattga tgtctggcgg gcaaggagca gacgaaaaag
     4201 taccagaggc cattgcgatg aaacaatatg ccatggaaca aggaatccct gaaagagaca
     4261 ttcttgtcga aaccaattcg acaaccactt tggaaaacat gctctattca aaggaaatca
     4321 tggatcagca aatgaaaggg ccataccgcg cgatctttag ttccaacaat taccacattt
     4381 ttagagccgg tctttatgcg cggcaagcca aattgaaagc aaatggtatt ggtgcaaaaa
     4441 cagctttcta ctacttgcct aatgcgtttt taagagaata cctcgccatc ttgatgatga
     4501 acaaaaaaag acatatgatc atttgcggat tgcttttcgc aggctccgca ttcttatcgc
     4561 tgattacttt acttttctaa aaaaacaagg tgtgacaaaa catatgtcac accttgtttt
     4621 tttctttcat tctcttaact attggcaaaa agagtatccc ttttttgacc gctacttgct
     4681 gagcagaata aataccgctg ttgcctgaac acataaagct gatcaagcag atcataaaga
     4741 agtatactgc cgcttgtgaa ccgaacaatt cgatccccat cacaaagcag gcaatcggtg
     4801 tatttgtcgc accagaaaat actccgataa agcccaatcc tgcaagaaaa ggaacagaaa
     4861 catggagcaa aggcgctagt gctgcaccaa gcgttgcacc aatttcaaac aatggtgtca
     4921 cttctccccc ttgatatccc gcgcctaaag acaaaactgt gaagaataac ttcccaataa
     4981 aatcatagac atgtgcctgt ccattaaatg attcttgaag taacggaaga ctcaatccga
     5041 gataacgttg tgtttgcaaa atcaatgctg ctgccacaac tacagctcca cctatcgtat
     5101 ttcgacaaac aggatgagga atccattgtg catatcgcgc ttttaaaaag acgatcgaac
     5161 ggctgaatac ccaaccaatc aaaccaaaag caatcccagc aacaaaaact ttgaagaaca
     5221 gcaacatact ccattcagga atcacaccca tttggtaatg tagatgagaa acaccatagc
     5281 tttctgtcat gaaatttgca aacagtgcag caaagaagct agggaagatc gcttctgttc
     5341 ggactttccc gattgccaac acttctaatc caaataatgt tccagctaaa ggtgtgccaa
     5401 atacagaact aaaacccgca ctgattccac tgataatcaa gatttcccgt tctgatttat
     5461 ccaatcggaa caaacgtgcc gtattatctg ctaacgctcc ccccatttgg actgctgttc
     5521 cttcacggcc aacagatccc ccaaataaat gggtagttat ggttccaaac agtgtaagtg
     5581 gaataagccg caacgggatt ttttcttctc caccatttcc ttgatcgatc actaagttgt
     5641 ttccacgact agaaagtccg ccgtgatacg catagagata agcaaaaagc gcaccactaa
     5701 ctggtagtag acaaaggagc caaggatgtg atagtcggat atctgtcaca actgtcaggc
     5761 tatttaagaa aaaagcagac aagctcccca tgaatatacc gagaatcgct gtgatcacca
     5821 gccacttcag catatacact aaaatgcgta ctggactcgg taattgtttt tccataaaaa
     5881 attcctcctc aataaaaaaa cgcctactaa agaaaggggc tgtccccaga ctttagtagg
     5941 cgtcattagc tatctttcgt tagcatttaa aggcgaacac catcacctat tcacttccat
     6001 taaaagatag catatttttc tgtaaaaaac aataaaatta tcgttctttc tttacacgtt
     6061 cagcaaattc atagaaagga gccaatttcg ttaactgttg attacattgg tcactatcat
     6121 gacaaatata attccccttt ttcgtatacg tgccatcaga acctgctttc gttgtagaaa
     6181 gaaaaagcga aacattcgat gttttctgac agattgcaca gattccctta tttatcgttg
     6241 gtgataaagt accgctaatc ccttttaatt tttcatcttc gtaatagacc atgaattttt
     6301 tctgcgtacc tggatcattc cagccgatgt acgtatgttc ttgcaagtcg atttcattcc
     6361 aagctggttg tttgagtttt ttcacttttc ggaataattt ctcgatttgt ggtttgctag
     6421 gctgcataaa cggctgaacg atttgcttca gctcctccaa tgctctttct gcttgcgctt
     6481 ttgtcagttt tacgtctaaa actgtcgtta aaaatgtatc gattctggca gttcgtgatc
     6541 taatatgtct cgaatctttt cagctgctag tgcctgaact gtttgtaccg tttttggatc
     6601 attgacagat gagtacgcat ttaataactg ttctacttct cttattataa aaaaatattg
     6661 gtatggtttt attgtttgtt ccatgatttt aaagtccttt cttctaacca aagtgcatac
     6721 tttgtagaaa aaagtgatct tctgcaaagt atgtgttacc tgaagatccc ggactctttt
     6781 aaataagata cgttttgcat cttatcatca ccccctttaa tgcttattat tctatgtaca
     6841 tgattcattc gataaataaa agtaaaccgt atcttgaaca gatagtcaac tgcaaacaga
     6901 aaaaaggact gtgacaaaag tcgtgtcaaa gtcccttgtt tcgaatgaat ggtgttcaaa
     6961 agctggcatc tgcggtaata agccgaaact tcacaaaaat ttgagaagca attttcgtaa
     7021 attccttctt atttcttgaa gctgaccact tctgtcacaa cctcaatatg gtctattatt
     7081 ggttttatct attaaatcga ggattctttc ccaaagtaac gttgccatct cttacgcata
     7141 cttgctgaca taggctgagc ggcttctttg actgcgcagt atttgtctac gaatgttacg
     7201 atatatcctt ctttgtactt aggcggtgca atcgttgcgc cccacatgtg cttcaaaatg
     7261 atatctcgct caagatccga caattcggtg atcttttctg cattctttac agcaattctt
     7321 ggatggatat acgcatgtgt gccttcatca aatttcgtcg tacgccaatc atagtagaac
     7381 agatcatgca aaagtccagc acgcgctgtt gctttagcat tgccacccca tttttttgcg
     7441 agcagataac tatagtaaga aacactgatg gaatgctcca aacgagtgga atgaacatgc
     7501 tgtgtgtaat tcgctaattt tttcactgct tctgtttcta aaagatcttc tacataagac
     7561 atatattctt cgtcttcacg ccatttttct gtcataatta tcgatctgcc acctttttga
     7621 atttcatttt cttctgaaat tgatctaagt ataccaccag tgttcggatt attctagtcg
     7681 ccttggataa aatagccaaa gcttaatagt tccttaatca taaagaaaaa tgataaagaa
     7741 caatccctgc cgcaacccca acattcaacg attccgcatt tcctttcatc gggatatata
     7801 cgttctgatc agtcaaagac aagatttcct gacttacccc ctgaccttcg ttccccatga
     7861 ttattgcgaa gttatctgat ttttctactt tgtctaatgc gtgtgcttct tcatttaatt
     7921 ctgtgccata cactgtaaac cctttgtctt tcattaaaga aatcacttct gtcaaatctt
     7981 tttgcaacac aggcaaatga taattgcttc cctgcatgct gcgcagcacc tttgtactat
     8041 aaatatctgc cgttcctttg cctaataaaa caccagccat atcaaatgca tctgccgtac
     8101 ggatcatcgt ccctacattt ccaggatctt gtacattatc taacaacagc catcctcctg
     8161 aaaaatctgg cgtgccttca gccgttaacg ccatcactgc taagattcct tgtggtgtag
     8221 gtagatccga tacagcatcc atgacctcat ccgaaactag aaaagtagaa atctctttgt
     8281 ttgcggccag ccagtctccc cattctttca tgcctcgctg tgtcacaaaa agttctttta
     8341 tttctgcatc agacgacgca gcttcttcaa tcagatggaa cccttccaaa agatattctt
     8401 ccttttcttc ccgatatttc tttttatgta gtttttttaa ttctttgatt cttggatttt
     8461 ttgctgattg gatctctttc acattcctca cctccccatg attatatcat ggaataggtg
     8521 cttgagcttg tttcatccta aaaaaatcgg tatcattaat ttataaaata ggaaagaaag
     8581 gtgacgaaca tgcgcaaagt taaaatgaac gtccaaggac gcgtccaagg cgtaggattt
     8641 cgctacatga ccaagatggt cgctgatcaa ctaggcgtga ctggaacggt aaaaaacgaa
     8701 gatgacggct cagtcacgat cgaagcaatc ggcaatgacg acatcatcca gaaatttatt
     8761 gaagaagtca agaaatctcc gagcccaagt ggacgagtgc agtatgtgga tgtccaagaa
     8821 gacccgatga ttgaggaacg aaagaaattt gatgtggtgg gataaggttg tgaaaaagct
     8881 ggtctgcatc aagcattaag gacaggttgt gaaaaatagc tctccatatt tttcaacagg
     8941 ctggacttaa tgccgtagat gcaagctttt gaacaccgtc gataaggtta ttcttgaggc
     9001 gctttgcctc aaaaattaag gacagcagtg aaaaagctga tctatcactt gcagtgagtt
     9061 catttgactc cgctttttcg ggcagaaaaa aagtttttag tttattaaag taagaaagaa
     9121 acacttggaa tcattctact ttttcctagt atttctttct tgattttttg tctttttttc
     9181 aaaatttttc gctacgtaaa agaacgaata tttatatgaa atttctatga agttgattga
     9241 attccatgcg cttttttagt atagttaagt ttgtgtaaaa attatagaag aggaagtatt
     9301 ctatgaataa atggaaaaac tggttattgg gatccggact tgtcagtatc ctgctctttt
     9361 tatctggctg tgtgcggatg gattcaaacg gaaaccctga cacttcggga atcgtttatc
     9421 gagtactcgt ccatcctatg ggccaagcga ttacatatct agttgaaaat ttcaattggt
     9481 cttatggctg ggcagttatt gcaatgactg tgatcgtccg tatcatcatc ttgccactag
     9541 gtattagtca atcgaaaaaa acaatgatcc aatctgaaaa aatgcaagcg ttaaaaccac
     9601 aagttgaagc agcccaacaa aaattgaaag ctgcaacaac acgtgaagaa caaatggcag
     9661 cacaagcaga aatgcagcaa gtataccgcg aaaacggatt gagtatgacc ggcggaatcg
     9721 gctgtctgcc tctattgatc caaatgccga tcttctctgc cttgtacttt acggcacgtt
     9781 atacagaagg tatccgggaa tcatctttct acggcatcga tttaggctca ccaagtatgg
     9841 tacttgttgc cattgcaggg gtcgcttatc tgcttcaagg atacatctca acgatcggta
     9901 ttcctgaaga acagaaaaag acgatgcgta cgatgctgat cgtctctcct gctatgatcg
     9961 tcttcatgtc gatcagtgcg ccagccggtg ttacacttta ctgggtagtc ggtggtgtgt
    10021 tcagctgtct gcaaacattc atcacaaacg ttatgatgaa accacgtttg aaagcacaag
    10081 tggcagaaga gttgaaacaa aacccaccaa aacaagtcgt cactccaaga attgatgtga
    10141 cagaatcagc taaaccagct gacagcaaac aagcaaccaa acaaatcaag caacccaaaa
    10201 acagtacaaa caataaaggc cgcaacgcag gaaagcagca gaagcggaag tagatagtaa
    10261 ataagagtgt aataaaaatt cattaacagt tttagcaatt aaaaatatcg accaagattt
    10321 ttgaaaaaga aatctggtcg atatttttat ttaagtgaat gtttaatttg aatcatcgat
    10381 tgatcgctat ctaattgcag cagcatcttt ttatgaagaa acaacttttt cttatctatc
    10441 aacgtagaca ggtgttgctg tttcttctaa tagtgtactt aattccttaa tattttgttt
    10501 tccttcttct aacatccaac tactcgcttt ttcttcgcct tcggtaacaa aaggcgccac
    10561 tcccttcgcc catgttgctc gcccacataa gacaccattc tccataaagg acaacgcgga
    10621 gataccaccc atctaaataa catccataaa cctttctagt agaagaatag tgatagtatc
    10681 catccctttt tctactggga atacaattac acgattcaaa gcttgataca caacatttcc
    10741 cttcttataa accgctattg taaccgaatt gttttgaatc acctttttgg gatagaaact
    10801 ggctcctttc cgcaacttct taaatgttgg tttcttttat actttctttg tagcaactac
    10861 aaatttcttc aaatctctaa atgtttgcat aacaaccgcc tttctgactt ttactcagga
    10921 tggtatttaa aaatcagcaa aataaggctt ctctccatct tttttatttc ctagctgctt
    10981 taaagacact cttgctgttt tttaatctct atcaaggggg ctctgaatct attttgatga
    11041 acttatctta ttaatttctc aaatgagctg tcagacacaa ctgtattttt tcaatctcat
    11101 accggacaac tatgccagct taaaaaaatt tcctctggca aaacttcttt attgaaaaat
    11161 gacaatgaaa aaagaccatt ctttttgttg aatgctcatt gtgtaaacat atttcctgcg
    11221 actgctcttc gaaccattct cagtgcaatc cctaatttat ctattaaatc ttcttttagt
    11281 tcctcatctt tcatattcaa aatttccttt gtatgttaca caagtttgtt ctctaaataa
    11341 cgcgaattgt aaaattaagt tagaaaaata aaaaggcatt tatggtacac tcaaattgta
    11401 tttccgacga aagaaaacaa aggagtgtaa ccataaatga cctacaaaca tcttaccata
    11461 gacgaactga caatgataga atcatattat cttcaacata ataagccggt tgaaatcgct
    11521 aaccgaatgg gacgtgctat acaaactatt tataatgt
//
LOCUS       DAZKCH010000084        11198 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000084 DAZKCH010000000
VERSION     DAZKCH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.085"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(13..897)
                     /gene="ftsX"
                     /locus_tag="ACG84X_002326"
     CDS             complement(13..897)
                     /gene="ftsX"
                     /locus_tag="ACG84X_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFP9128155.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIRPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            complement(890..1576)
                     /gene="ftsE"
                     /locus_tag="ACG84X_002327"
     CDS             complement(890..1576)
                     /gene="ftsE"
                     /locus_tag="ACG84X_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFP9128156.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(1681..2782)
                     /gene="prfB"
                     /locus_tag="ACG84X_002328"
     CDS             complement(join(1681..2709,2711..2782))
                     /gene="prfB"
                     /locus_tag="ACG84X_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFP9128157.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(2908..5442)
                     /gene="secA"
                     /locus_tag="ACG84X_002329"
     CDS             complement(2908..5442)
                     /gene="secA"
                     /locus_tag="ACG84X_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFP9128158.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(5664..6215)
                     /gene="raiA"
                     /locus_tag="ACG84X_002330"
     CDS             complement(5664..6215)
                     /gene="raiA"
                     /locus_tag="ACG84X_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFP9128159.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(6343..7062)
                     /locus_tag="ACG84X_002331"
     CDS             complement(6343..7062)
                     /locus_tag="ACG84X_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFP9128160.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            complement(7059..8372)
                     /locus_tag="ACG84X_002332"
     CDS             complement(7059..8372)
                     /locus_tag="ACG84X_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFP9128161.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            complement(8453..8773)
                     /locus_tag="ACG84X_002333"
     CDS             complement(8453..8773)
                     /locus_tag="ACG84X_002333"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9128162.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            complement(8881..9168)
                     /locus_tag="ACG84X_002334"
     CDS             complement(8881..9168)
                     /locus_tag="ACG84X_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128163.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            9295..9939
                     /locus_tag="ACG84X_002335"
     CDS             9295..9939
                     /locus_tag="ACG84X_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFP9128164.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(9998..10705)
                     /locus_tag="ACG84X_002336"
     CDS             complement(9998..10705)
                     /locus_tag="ACG84X_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9128165.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(10925..11095)
                     /locus_tag="ACG84X_002337"
     CDS             complement(10925..11095)
                     /locus_tag="ACG84X_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128166.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
BASE COUNT         3053 a         2430 c         1957 g         3758 t
ORIGIN      
        1 tatattgtgg tattagaatt tcaaaaaacg tctcatagaa atgatcgagc caagtgaacc
       61 aatgatcaca ccaatgccga ccattaaaag attgattttc caaacgatat tttgtggacg
      121 aatcaatgaa taatgggaac gtaataatga tggattgatc aattggaaaa accatgcata
      181 accaaatgtg atgatcaaaa tcggaagaat cgcaccgatc agaccgatcc agccaccttc
      241 aaggaaaaac ggccagcgaa tatatccatt ttttgcaccg actaaacgca tgatttgaat
      301 ttcacgctgt ctagacaaaa tcgtgatccg aatcgtgttc gaaatgagaa acatcgctac
      361 gaacagcagc aatgccgctg caactaatcc ccatgtccga actgcaccag cgatttggaa
      421 aatccgatct gaggaagctc caccgtaatc agaacgagaa acattcttca aatctgctgc
      481 ttcttctgct acttgttttg tataagaagg atcagtagca cttactacat acacatcata
      541 taacgggtta ttgtcacctt caaacaattt ccaggaatca cccatttcgt tttggatttt
      601 tttcaattcc tgttctttgc ttgaaaattc aactttttta acatgatcta agtcattcaa
      661 ttctttttct agctttttca tctcttcgtc ttttgtaccg atatctacga atacagatac
      721 atcaacgttt ccttctatat cctgagctaa tttagttgca ttcatgataa ctgccatgaa
      781 tacaccgact aaagtcaacg tgatcgttac cgcactgact gaagcaactg tcatccagcc
      841 gttacgtttc aaactcttga tactttctaa taaatggcgg aaaaaggttc taatcatcgt
      901 atccatattc cccttccgct tgatctcgaa taatgcggcc gttttcgata gcaattactc
      961 ggtgccgaat cgtatttacg atcgtactgt tatgtgtagc catcacgaca gtagttcctt
     1021 gggcattgat ccgatctaat aatttcatga tttcccatga gttttctgga tccagatttc
     1081 ctgtcggttc atccgcgata agtactttag gcgtattcac gattgcccga gcaatagaga
     1141 cacgttgctg ttccccaccg gataattcgc taggaaagac tcgaactttg tgtttcaaac
     1201 caacaaggtc cagcacttcc attactcgtt ttttgatatc tcgaggtttt ctgccgataa
     1261 cttgcatagc gtacgcaaca ttttcatata ctgtttttct tggtaataat ttatagtctt
     1321 ggaacaccac gccgatttct ctgcgtagat aaggaacttc gcggtttttg attgctatta
     1381 gatcatgacc tgcgacgttc aaagttcctt ttgaagcttt ttcttctcga tacatcaatt
     1441 tgatgaatgt agatttaccg gctccagacg gaccaaccac atagacaaac tctccttgtt
     1501 cgatgacaat cgagagattg cggatagcgg tcgtaccatt tgagtacttc ttcattacat
     1561 ccttcatttc aatcatggcg ttctctccat atctttttca gtctttagct attatagcat
     1621 ggcaatgttt caacatgctt gcaaaatctt acaattttat ttcaatttaa caatgagttc
     1681 ttattgtaga tgcattttta aatagccgtc aataaataaa tcaaggtcac cgtccataac
     1741 tgcttggaca tttcctgtct ctacgtttgt ccgatggtct tttaccatag aatagggatg
     1801 gaaaacataa gaacggatct gtgaacccca gccgatttct ttttgttctc ctcgaagtgc
     1861 agctgcttct tgttctttct tttccacttc taattgataa agcttagctt ttaacatccc
     1921 catcgcttgc tcacggtttt tcaattgtga gcgttgtgcc tgactagcta ctactgttcc
     1981 tgtaggcaag tgagtgatcc gtacagcaga ttctgtttta ttgatgtgct gaccacctgc
     2041 accacttgct cggtacgtat cgattttcaa atcatctgga ttgatttcta tatcgatcgt
     2101 ttcatcaagc tctggcatca catctaccga acaaaaagaa gtatgacgtc gtttcgctga
     2161 gtcaaaaggc gaaatccgta caaggcgatg aacacctttt tctgatttta gataaccaaa
     2221 agcgttatgt cctttaatca gcagggtcac actcttgatc cctgcttcat cacctgcttg
     2281 ataatctagt gtttctactt gatagccatg ctgctctgcc caacgtgtat acatacgtaa
     2341 aagcatgctg ccccagtctt gggactccgt tccgccagcc cctggatgca attcgacgat
     2401 cgcattgttt cgatcataag gtccgtctaa cagcatagat aattcatacg tcttcatttt
     2461 ttcatctaat gcattgatac gtgtttctgc ttcttcttgc attgctgcat caggttcttc
     2521 ttgcagcatc tccaccatca attcgatttc ttctagttct tcggcaagag aatggaattg
     2581 gtcataggtt tctttattag cgttattttc gctgatcact ttttgtgcgg cttcgctgtc
     2641 atcccaaaaa ccaggttcag ccatttttgc ttctgcttcc gcgatgtctt cttccagctg
     2701 atctaagtca aagagacctc ctgaaacttg tgaccttttc ctgcatttct gtcaggagat
     2761 ttcgaatttc ggatatttcc atgttttttc cttctttcac tatacttttt tcattatatc
     2821 tagtctaaca gaatcagcaa ataacagaaa gaaggtgaga cgaattctta aaaaaagaat
     2881 ttgtctcacc aatcctgctg tcagaaatta gtttgcattt tttccatgac agttcttata
     2941 ttttttcccg cttccacaag gacaaggatc atttcttccg accttgttca catggattgg
     3001 ctgttttttc gcgctagtat tactattttc tttggcatct ccgtcttctg agtgagaagc
     3061 tgttccttga gaaacctgtt cacgctgtac gttttgacgg atctcagctt tcataaagat
     3121 tcgagtgact tcatactcga tggcgcctac catatcttca aacatcttat agccttctgt
     3181 ttgatattcg actaatggat tgttctgtcc ataagcacgt aagccgattg actgacgtaa
     3241 ttgatccatt gcatcaatat ggtctgtcca tttagagtcc acaacacgca agatcacgac
     3301 tttttcaaat tccaacagtt gctctggacc atttagttga gccgctttgg tattaaatac
     3361 ttcttgtgct cgttcgttta gatactcttt gatctcctga gatgtttttc cttcgatatc
     3421 tgcaagagta atactatctt catggacaag agtactgccg gcaaaatcga tgatactttc
     3481 caaattccaa ttttctttct ctaattgtgt atgcgcatct actacacgac tgattgtccg
     3541 tttgaccatg ttcattagtg gcttggataa gcttttttct tccatgatta cttcttgtcg
     3601 ctgtttatag attacttcac gttgttcacg catcacatca tcgtattgta agacgttttt
     3661 acgtgtgtca tagttatttc cttctacacg tttttgtgca gattctactt gtttcgtcag
     3721 catcttgctt tggataacag catcttcctc accgatcttc atccgatcta agaaagcttt
     3781 gattcgttct gaaccgaatc gtttcatcaa atcatcttcc aatgacaagt agaattgtga
     3841 cataccaggg tctccttgac gtcctgcacg tcctcgaagc tggttatcga tacgacgaga
     3901 ttcatgtcgt tctgtcccga taactgctag accaccaagt tctcttaccc caagtcctaa
     3961 cttgatatct gttccccgac cagccatgtt ggtagcaatc gtcacagcac ctttttgacc
     4021 agcattcatg atgatctctg cttctttaaa gtgatttttc gcattcagca cttcatgagg
     4081 aatacgttct tgattcagca tatctgataa taactcagat gtttcaaccg caacagttcc
     4141 gactaacaca ggttgacctt tgcggtagcg atctttgata tcttgcacga cagcgtggaa
     4201 cttgctttgt aatgttgggt aaagtaaatc tggacgatca tcacggataa ccggacgatt
     4261 tgtcggaatc tggtatactt ggatgttata aatttctctg aattcttctt cttctgtttt
     4321 agctgtacca gtcattcccg caagtttctt gtacatacgg aaatagttct ggaaagtgat
     4381 cgtcgccatg gttttcgttt cgtcttcgat ctctacgcct tctttagctt cgattgcttg
     4441 gtgaagtcca tctgaataac ggcgtccatc catgatccga ccagtgaact ggtcaacaat
     4501 cagtactttt ccgtcttgga caacataatc gatatctaaa agcatgatat agttggctct
     4561 caatgcttga tccaagtgat gggtcaatgc agtattttca atgtcgtata agttatccaa
     4621 accgaatgtt tcttctgctt tttcgatccc tgcttcggtt aaactgattg tttttgattg
     4681 tacatcgatt ttataatctt cttcttcttt caaacgtttc acgaagttgt ctgctcttgt
     4741 atataaagct gtggattttt ctgcttgccc tgaaatgatc agcggcgttc tcgcttcatc
     4801 aatcaagatt gagtcaactt catcgacaat ggcataattc agcggacgtt gtaccatttg
     4861 atggcggtaa acgaccatat tgtctctcaa gtagtcaaat cctaattcat tattcgtact
     4921 ataagtgata tcacaattat aagcctcgcg tttttcatcc gaagattttg agttgatatt
     4981 caaccccact gttaatccta agaaattata aagttcgccc atttccgtcg agtcacgggt
     5041 tgctaaatat tcattgacgg taactacgtg taccccttcg ccagtcagag catttagata
     5101 tactggcatc gttgcggtca aggttttacc ttcaccagta cgcatttcag ggatatttcc
     5161 atcgtgaagc acgattccac ccatcaattg tacgtggtat ggatataacc ccaatacacg
     5221 ttttgctgct tctcggacga ctgcaaaagc ttccggaagt aattgatcta atgtttctcc
     5281 tttttggtat ctgcccttga attcagcagt ttttgcctgt aattgttcat cagttaatgc
     5341 tgccatttgg tcagcgtatg cttcaacttt ttttgcaatg ctatctaaac gttttagttc
     5401 tttcttatcg ttttcgataa gtgaacgaat caaattggcc atgcgttgtg taatctcctt
     5461 ttccttctgt gtattatcca gactatgtag actttacttt tcattttatc attagttata
     5521 gataattgaa atatcttaag cgtattaaag taagaacttc ataatttatt catatttcat
     5581 ctaaaagagg aggaaactca aaaaaacttg cggcagctgt cagtagctgc tgcaagtttt
     5641 cgttgttatt taagtaaggc tgatcagtct gtttcaatca gtccgtattt tccatcttta
     5701 cggcggtaaa cgatacttgt accatttgtt tctgcatctt caaaaataaa gaagttatgt
     5761 cccagcatgt tcatttgtaa gactgcttct tcactatcca ttggtttcaa tgaaaggcgt
     5821 ttcgtacgta cgatatctaa ttcagaatca ttttcgtttt cgtcctcttc attgaataaa
     5881 gcagcagcat ctgcagtatt catgcccgtt tcacgggatt tacgattaat ttttgttttg
     5941 aatttgcgga tttggcgttc caatttatca acaaccaaat cgatacttgc gtataaatct
     6001 ggagaagttt cttcggcacg taatacaaga taaggtaatg ggatcgttac ttccactttt
     6061 gctgtttttt ctgtataaac ttttaagttc acatgcgccg ttgcatcggg tgcgtcactg
     6121 aaatagcgtt ctagtttgcc tacttttttc tcaacgtagt cgcgaatcgc ttcagttact
     6181 tcgatatttt cgccgcgtac attatatcta aacataaaaa ttaccccttt cgtctaccac
     6241 aatcaagaag gagaaggacc actctttccc tcttcttaat tctattatat cgaactctag
     6301 gttatttgca aattaaatcg ctatcaaatt tccacatcta attcatctcg ccaaagaaat
     6361 ggttcggatg attttcggct gtgcgacctg caaacaatct gctgcgtgga aaagagtctg
     6421 tcctgttgta tagacatcat caataatcaa tattttttta ttttgtatct tagaaaaggt
     6481 gactgcaagt tcaaaaggtt gaggcatctc caatctttcc tttcgcgtgt tttttgcttg
     6541 agccagcaga tgcttctctc ttttgagtag catctgaaaa ggaattcttg ctgctttcaa
     6601 catctcgctt acttgattga atcctctttc tgttcgcctt ttttcagata aaggtattgg
     6661 acaatagatg tatgtcgggt attctttttt tatctgcgtc catttatatg caaaggtgcc
     6721 tgctagtcgg atatctccca taaacttgta ttgattgagc caggccttca tattttcatc
     6781 gtacacaaaa aaggcacggt gctgaaaatc ataggtcgga tatttcttct tccattcttg
     6841 acagtcactg cagtaaacgg gaatagactt tactttcttt ttcgtactct ctagattgaa
     6901 atggattggt ttttgacagc cagaacagcc tcttgtttcc aataaatgaa attgtgcgcg
     6961 acaaactgaa caagtctgag gtaatctgta tttcgaaaca ccaataatct cgctgaatgt
     7021 taaattttgg aagatatctt tactgcagca actgcacctc acagcatctt cttcccttct
     7081 tcattcattt ctttgatttc ctgacaagct tttcgaatag ctgcagtttt ttcttcatag
     7141 aaaaagtata cttgactgtt cgtataaggc cctttacgat cggctcttcc tgcgatttgt
     7201 accaaagaag atttagtaaa aaccggatga tccgctccta aaacgataac ggatattctt
     7261 tcaaatgtga ctccacgttc aaggatcatc gtggttaaca gtatatcata ttttgcttct
     7321 cgcattttct ggactttttc cgcccgctga ttgtctcttg aagaaacatc tgtgatctca
     7381 tatctcggaa gagcctcttg aagtgtggct ttcaaacgat gcatcatcgt gatacttgga
     7441 caaaataaaa ggatatggtt ttctttaatt aattgatgaa tgatccgcac caaagatttt
     7501 atcttcttct tgttcttgca tttttgtcgc caattattca tgaaaaccaa gacgggttca
     7561 ggaagcaaac gccgatgaaa gcgtaaagca agtttgtgga tgtcaaacgt ctgcttgatt
     7621 tcctttagta actttttatc aggtgtggca cttaagtaga tgaatcgtcc gtctggttta
     7681 atcgctgttt gcacagcatg agctaatcct gcatccccgt tataaggaaa cgcatcgatc
     7741 tcatcgatca ctattaaatc aaaggaccga taaaaacggt atagctgatg aatcgtacag
     7801 ataacaaaag aagtaaaggt ataagccgtt gctgtattcc catggagcaa cgtgattttt
     7861 tcttctggaa aaacataacg atagcgtaaa aacaattcat tacaaacatc gactcgcggt
     7921 gtacaaatcg ctactcttcc tccagctttt aaagtttcca ctaaaatagg ataaagcatc
     7981 tctgttttcc ctgcacctgt tacagcccaa ataagatgat gtcttttttc tgaatggcaa
     8041 agtattctct ttgagatttc cgtttgtttt tcagtaagct gtcctgtcca aaaaaagacg
     8101 acttctcgag gttttgcttc aggctgatca aacaaatata aatcttgttg agtgtcgcat
     8161 cgccctaaat atagacaatg tgtacaaaaa taaccgtaat ctgcaagctg tccatcaatg
     8221 acggacgtcc tcattccaca gcgatgacaa agaatccagt tgcccaaacg ttccactgct
     8281 gcgatcttct cataatttgg taaatttacc tcctcacagt ctattgcttc aatatctctc
     8341 gtcagaagcc ttctacccca aaaatgattc atattcttcg ccctaaaaaa atatacgaaa
     8401 aaacaagcga tctatttttt ggatcgcttg ttcgatagtt atactgttct atttattcac
     8461 ctatgagcgt gattgcttga tctaacactt tttcgccatt catcatacca taatcagcca
     8521 tattgatgac atctaaagga atgccttttg gttccagacg tttctcaaaa tcagctttca
     8581 taaagcgaac ttgtgggcct aataacaaca catccacgtc tttatttgca aggttgttat
     8641 ctgcgtcaga agcggacaca gcgaaaatat ccgagtcgat tccttttgct tcagcagctt
     8701 tttgcatttt tgttactagt aaacttgtgc tcataccagc cgaacataca agcatgattg
     8761 tttttttagc catacttttc tctccttttt aaaacaaact atgcaaacgt tttcttcgcg
     8821 tctgttactc tattatataa aaagaaagaa atttgtcaac gttttctaaa cgcggtttat
     8881 ttaatcaaat agccaactag atttcactaa tttattgaac acgacatatt ctttgtccaa
     8941 attgatgaca actacttcat agcctgcatt tatccagcca taggcacctt tttcagggtg
     9001 tttataatca tttgcccacc aatctgtact ttcccttgct gttttgggaa gtccgttact
     9061 gggaaacagc agttcgtcaa attgggtaaa ggtcaacgtt acttgagagc cgccattgtt
     9121 cttcaaataa tgcgtaattg catcgtactt tttcattcgt tcctgcatcc ccagatccac
     9181 ctgcctttgt ctttattatc gcatactaca gcaattgcgc aaccgttaca gtgttgaaac
     9241 aacctagaac tttatttata ctgaataaag aaaatgaaaa aaagaggtga caagatgatc
     9301 gagcgctatc gtacaataaa agaaaatgga caaagtgaga ttgagatcaa aaaatcacgc
     9361 tttatctgtt ctcttagacg aatagaatca gaggaccaag caaaaagttt cattcaagaa
     9421 ataaaaaaag aacattggaa agcgaaccat aactgcagcg ccttcatcat tggagaaaaa
     9481 aatgaaatcc agcgaagcag cgatgatgga gaaccaagtg gaacggcggg cgtaccgatg
     9541 ttggaagtcc tcaaaaaaaa tcaactgatc aatgtagctg cagtagtcac tcgatatttt
     9601 ggaggaacga aactcggcac aggcggatta atacgagcat acactcatgc ggtctctcaa
     9661 gcattgtctg acattggaat cgtagaaggt accttgcaac aggagatctc tgtgatgatc
     9721 acgtatccgc aactaggaaa attacagaat tatcttgaac tccaacattt ttttataaaa
     9781 gaaatccaat atactgatca agttagcgtc atctgtgctg tagatgaaaa aagtgctgac
     9841 cactttaaag aatccatcat tgagctgctg aacggacaag tccaatttga agagggttct
     9901 gtttcttatc acgagcaact gataactgat catatataaa aacaggtgat tctgattctc
     9961 ttttatttct aataaggaat cagggatcac ctgtttttta tttttccaaa taaaactcaa
    10021 aacgatttcc tacgtattgc gtacgcacat actcaaacgg cgtaccgtct tcaaaataag
    10081 aaatctggcg caaacgaaga actgcatctc ctcgttttac ctctaaatag tcagcaattt
    10141 tctcagaagc caacacagca gtaatcgttt gattcgctgg accgatcttt ttcccgcctt
    10201 tttcttctag cgtgcgatac aacgattcag taatctctgc tttgctgtag ccatcgatca
    10261 gcttttgtgg aacactggca acttcaaaac aaatagggac atcatctgcg aaacgaatac
    10321 gttccattcg caagatcgtg tcatctttac tcaagtttag tttttccatt tcacttgagc
    10381 ttggcgaagt caagaaataa gagattgtcc gactagacgg tactcgattt tgtgattcca
    10441 taatttctgt aaaacttgtt gcaccagaca ttttttcttg tactttttct cgcgcaacat
    10501 acgtacccga accgatcttt ctttctaaga ttccttcatc tgccaagttt tgaattgctt
    10561 gtctcaacgt catacggctg acattgaatt tcactgctaa ttctctttct gaaggaagac
    10621 ggtctccgac tttccatata ccctgttcga tttcattttt taattggtca tgaatctgta
    10681 tatatacagg taattgattc gacataacgt acacccgtcc tttcgtttct tctattataa
    10741 ctggtatata cctgattcac aactgaaaaa gataaaggtt tctatccatc aacagaggat
    10801 ttagacacac atcgttctcc ctactcctat tgtcagaaac aattttttag atatgttcaa
    10861 cctagaaaat aacaaaagac cctaaaatcg atgaaaatgc cgacttatgg atcttttgtt
    10921 attattagcg gtttttagcc atccattttt ttgtatgatt cgttgggcgt tttgatttta
    10981 cctggaccgc ttttccgcct tttttcggaa tattcacttc aatattgtat ttttctgatt
    11041 tgaccaaatc atataacttt tcagctgctt cgtctacttt ttctttccat ttcatgtgga
    11101 tccctccaat tcttgtagtt aacttaactc tatcttaatt cagcagaatc ttcaaggaac
    11161 aaggtagcaa agcaaaaaaa agagctctcg aactaacg
//
LOCUS       DAZKCH010000085        11188 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000085 DAZKCH010000000
VERSION     DAZKCH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.086"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            106..705
                     /locus_tag="ACG84X_002338"
     CDS             106..705
                     /locus_tag="ACG84X_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HFP9128167.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
     gene            705..1280
                     /locus_tag="ACG84X_002339"
     CDS             705..1280
                     /locus_tag="ACG84X_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HFP9128168.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            1305..4976
                     /gene="brxC"
                     /locus_tag="ACG84X_002340"
     CDS             1305..4976
                     /gene="brxC"
                     /locus_tag="ACG84X_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HFP9128169.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            5040..8672
                     /gene="pglX"
                     /locus_tag="ACG84X_002341"
     CDS             5040..8672
                     /gene="pglX"
                     /locus_tag="ACG84X_002341"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HFP9128170.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            8788..>11188
                     /gene="pglZ"
                     /locus_tag="ACG84X_002342"
     CDS             8788..>11188
                     /gene="pglZ"
                     /locus_tag="ACG84X_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HFP9128171.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VN"
BASE COUNT         4206 a         1512 c         2117 g         3353 t
ORIGIN      
        1 tataataaat atgtattgta tagtagatac taaaaaatga atgctaacga tgagcaaaaa
       61 acacttgttt acttattgaa ttatagatga ttaggaggca atctattgaa taaaaaatat
      121 tctgctggtc tagtttctaa acgcttttgg ttttcagagt tcaagttata tattcaatta
      181 cgactagaag gatatacaga tatagaaatt aaagagaaaa atgaacatga aaatattttt
      241 tttgcagtga gcagtaaccg tcaaaaagaa atctatcaga acgtgaaaag gagagttagt
      301 caactggatg aagctggatt gcaacttttc aatcagttaa atatagataa tcaaaagtta
      361 gtgaatttga tttccatcct tatgattgat gatcttttta atgaatttat gactgaggta
      421 tatgctgaaa atctacgtaa aggaaatttg caattaacac cagttgatta ccgttctttt
      481 tttacagaga agcggagaag ttcagaagat atttcaaaat ggaaagatta tacgattaaa
      541 cggcttattg ccgcttatca aacgaatcta attgaaacag gattagtcag aggggaaaaa
      601 gaatatggac gaatgactcc gatattatta gataaacgat tgattcaatg gttagttgac
      661 aagaatcgta aagatattgt actagcactg ggaggaattt tataatgtca ttatcgattc
      721 aagagcattt ggaaaagttg aatgaagtaa ttcaaaaaga agatttttta ttgaatcgtg
      781 gtttaggtaa tgaagtaggc tattatatct ttgactacga tccgaaagac gagttaattg
      841 taagagatta tattaatgat atatctggaa catctgttgg tgataattat gaagtgaaag
      901 tttataatct ctatgtgatt atgttagagt atctagaaaa acgcggtttc actgaaaaag
      961 cgattaagat ggaagaacga cgtggtttac aaaaattagt ggaaagcatt ggtcgtttat
     1021 tgaaaatgga tttacctgag gaagaaaatg tattttttga atatgtggat gcccatacac
     1081 cagaaaaatc agttgtgttc ctgacaggaa ttggcgaatt atatccatta attagagcgc
     1141 actctatttt aaataaaatg catcaggtat ttgatcgcgt accagttgtg atgatgtatc
     1201 caggggaata tgatgaatta agtttgacaa ttcttaatac caataaagat gataattatt
     1261 atcgagcatt tagaatttag ttgggatgga aggtaggaga ttaaatgcta attaaagata
     1321 tttttgcaaa accaattgac cgaaatattc aaggagttat taaggtcggt caagcaaagg
     1381 atgaaaatgt tcaacaagaa ttagaagaat acgtggttac gaaagaacta caaaaacact
     1441 ttaaaacaat ttttgatgcc taccaacgga gtatcaatac accaacagat aaaatgggtg
     1501 tttggattca ggggttcttt ggttcaggta aatctcattt cttaaaaatt atttcttact
     1561 tgctcgcaaa tcgagaaata aatgacaaga aagccattga ttacttcaaa gaagatggga
     1621 aaatcaaaga tccactgact ttggcaacga tggaacggtg ctcacaaata aatacagatg
     1681 ttattctgtt taatattgat tcaaaaagtg atgcaggtgg taaaaaagac aaaaacggaa
     1741 tcgtgaatgt ttttttaaag gtatttaacg aaatgcaagg attaagcacg attccacatc
     1801 tagcagattt tgaacgtcgg ttaattaaag aagaaaagtt tgatgcattc aaagctgctt
     1861 ttgaagagat taatggggca aaatggcaag aagagcgcca tgagtttgat tggatccaag
     1921 atgatatcaa agaagcggca cttaaaatcg attttatgag tgaagccgct attgataatt
     1981 ttttagaaaa agcatcagga aattatttaa taagcattga tgactttgca aatctagtta
     2041 aaagctatct tgattccaaa gaagcagacc atcatattgc ctttctagtc gatgaggtcg
     2101 gacaatatat cggcggtaat cgtgagttga ctttgcagtt acaaaccgtt gtggaagatt
     2161 tgggtcgaat ttgtgaaggt aaggcttggg tattagtgac aagtcaggaa gcgattgatc
     2221 acgtaacaaa ctttgataac aattctgata atgatttttc taagatcaag gatcgttttg
     2281 ccacaactgt gagtttatct tcagcaaatg ccgatgaagt aattaaagaa cgtattttga
     2341 agaaaaaaga gtttgccaat gattctttag ccttacaatt tgaaactgtt caaacagaat
     2401 tgaaaaataa attactcttt gttgatagtc ctgaattaaa gctcttccaa gatgctgaaa
     2461 attacgcaga agtttatcca tttattccct atcaattcaa tttattgggg caaattctaa
     2521 ccgagattcg taatcacagc tatcaaggat caaacttatc gtctggtgaa cgttcattac
     2581 tagcaatgtt taaagaagcc gctgaacgaa ataaggaaaa tgatacaacc agtttggttt
     2641 ctttagatca gttttattac tcgttagaac gttggattga tacagcaatt agccgagtga
     2701 ttacacaagc tacaaataat tctcatattc aaagaccaac tgatatagat aactttaacg
     2761 taaatgtctt acgaatttta ttcatgatta aatatgttga tcaagccatc aaaccaaatg
     2821 ttgaaaatat tacgagcttg atgataagaa atatcaacga agaccgcctg gaaactaaaa
     2881 aacgagtaga agaagcattg gaccttttaa ttaaggaaaa ctttgtgcgg aagaacttag
     2941 atagttatat tttccaaact gatgaagaac aggaaattac tcgtgagatt aaaaatcaaa
     3001 atattacaga tagtgatttg atcgtagaac tatctaaacg aatttttgac ggcgttctag
     3061 accgaaatag ttttgcctat gaaaaattag gcatgtcagg tggaaataaa tttaaaaacc
     3121 ggtatacgtt tacttatgca caagtgttag atcaacgtcc atacaagcaa gctggaaatg
     3181 ctgaaatgac agttaatttt atttcaccat actctgattt agcaggtcaa gaggcagaac
     3241 ttgcgcttaa gagttcccgt aacttattat tcgtagaatt gccatcagat aaagaattta
     3301 aagatgatat agcaatgtat gctagaatga atctttattt aacaacgact tattcgagtg
     3361 tagtaaagaa ctttgacgcg attcgttcgg aaaaatctgg tgaattacag gaactaagtg
     3421 caagtatcaa cgatcaatta aatgaactgt tgaaatctgc aaaatttttc tataacggtg
     3481 cagaaattca actgacaggc tccgacttta aagcaaaatt ccaatcagca cttcagaaaa
     3541 tggctgaaga agtataccat aaattaaacc aaattgatgc gcctaaagaa aaagaagata
     3601 tcttatattt agtgaaagaa agcaaaaatg aaattattga agatccatca aatgagcaag
     3661 cagttcagga aattttcaat tttatcaatg atcaaaagag aaatcaccta acgattacga
     3721 tgaaaacaat tcgtgatcgt tttgaaacaa aacaaccgta tggattcaca gaacttgatg
     3781 tggaatggtg catcgctaaa cttttcatgt ctggtaaaat tgatttactt tataacaatg
     3841 tacaaatttc acggatggat gatccaaata gtattgtaat gattattcaa aaacgacgag
     3901 aaagtgaaaa gataaaaatt gaaccaagcg cggtgatttc gccaaaagca aaaaaattgg
     3961 ttgacgaaat cggtagagaa ctgtttcaaa gtcgtaatat tgttgatgaa aataacaatg
     4021 aacatacaat ggaaaatttc aagaaatatt taaaaggtca attagacaat ttacgctctt
     4081 attttgattt acaaaacact tatacctacc ctagtgctta tgaatatgag caaataaaaa
     4141 aatatcttga agtaattgtt caaacgtcag atgttgaaga ctttttttat acaatcaaaa
     4201 aatatcgcga tgaattattc gactgggctg aaacatatga taaaattaaa aatttccaca
     4261 agcaaaatag tactcagaaa aaaatctggg agaatgcaca agataaaatt agattaatcg
     4321 aaaaaagtcg gcgtcaaact tctagccaag aaattgatca attgattcat gagatgaaaa
     4381 ccattttgaa aaaggctgat ccttattcag atatgatgaa actaaatgag ttgattcaag
     4441 aatttattga acaatataat caactgttag agttggaaag tcaggaaata ttaaataaat
     4501 taacggaaga aaaacaagca acatttaaat tattagaagg aaaagatttt aaggatcaat
     4561 ttgtaccaat agttgaccaa gaatttcaag aactgaaagc aaaaattgaa caagcgaata
     4621 ctatagatga tcttgttttc ttatcattaa acgtagcaga acagtatttg atctttaatc
     4681 aacgtttcga taatgaagaa aaccgcagac gtcaagaaga acaagcacgt aaacaaattg
     4741 aagcagcaaa cttgattcgt gaaactgaaa aagatgaaat agactctgca gcaaaagctg
     4801 aagaaatagc gatagtaaaa cctactattc aacagaaaac agtaccaatg agaacactta
     4861 acgttcatgt taaaactatt aagtcagcag cagatattga tgagttaaca gctgaaatta
     4921 atcaaaaact gaaggaacaa cttcaagaaa atacagaaat cacgattcaa ttctagtgaa
     4981 aagacaggca taaaaaggtg cctgtctttt caaaggttac atatagaagg gaaagaaaaa
     5041 tggataagaa agcgataaag aatttcgcgg tcaatgcccg tagaaaatta attgatgaag
     5101 taatgactaa agcaaaacgt ttaggaattg atgaatcaaa aattgaagat gtgaagaaaa
     5161 ttgatagcaa tttacaagaa atcgaaaaat caggaataag aattcaagga aaagaaatag
     5221 cgcaaagaaa caaattgatt gcagaactaa aacaacgtgc ttctgtcact tcttattcag
     5281 aagcttttca agagttaatc gaagaggttg cttatacgtg gtttaaccga ttgattgcca
     5341 ttcggtttat ggaggtaaat gattatttac ctgacacgta tcgtgtatta tctagtgaaa
     5401 taagtgggaa aattgagcca gatattatta cagatattta tgatgccgat atctttgaag
     5461 aattatctag taatgaacag caacaagtca gaacttggaa aacagataat tcagcagaag
     5521 caatggacaa gctgtatcaa ttgattttta taaaaatctg taatcaattg aatgattact
     5581 tacctgagct atttgaagaa gtagaagatt atacagaact tttgtttaca gcttcttata
     5641 ttaaaaaaga tggtgtaatc gctgatcttt taagtattcc agaggatgat ttctatgttc
     5701 aagctggtgg acaggtagag attattgggt ggttgtatca gtactataat agtgagccac
     5761 ataatcaagt ggtgaatatt tataaaggga ttgtcaaaaa acaagatatt ccggcagcaa
     5821 ctcaactatt taccacagat tgggtcgttc gttatatggt tgacaatagt ttaggaaagt
     5881 attggttaga tcattatccc aatagtgaat taagaaataa gttgaaatac ttaattccag
     5941 ataaatatgc ttttgaacaa gcaacatctg taagtaattt aaaaccagaa gaactaaaaa
     6001 ttatcgataa cgcaatgggg tctgggcata ttttagttta cgccttcgat gtattgatgg
     6061 aaatttatct tacgttagga tattctgagc gtgatgctgc acgtgcaatc gttgaataca
     6121 atttatatgg tcttgaaatc gataaaagag cgtatcaatt gtcttatttt gcaattatga
     6181 tgaaagggcg tcaatacgat cgtctttttt tgaaaaaaag tctatcgccg aatttaagag
     6241 agtttattga ttctcctaaa gtgacagacg agtatcaaga gcgtattagt gaattgaaca
     6301 atgataagta tagtgaacgc tggaatgaat acaaagagtt aatttttgat caatttgaaa
     6361 atgggaaaga acttggatca atcattaagt tagtcgataa aaataatcag gcaataacta
     6421 aagaatactt aggaaaagta agagagtata tatcaaaatt caacgaattt acgaatatgg
     6481 atattcttta tgggatgaag gaaatacaag aaaaatactt gcacattctt gacgtggctg
     6541 aaatgctagt tgataaatat gtagcggtag tcactaatcc gccttatctt aataaaatgg
     6601 ataagaaatt aaaaaaatat gtaaatgata actattctga tgtcaaaaaa gatctatttt
     6661 ctgtgtttat taaattgaat agccaaatgc tgattgataa tggatatgct tcctttatga
     6721 cgccatttgt ttggatgttc atttctagct atgaaaagtt acgctcattt ttaattaatg
     6781 aaagaaacat ttctagtttg attcaaatgg agtattcagc ttttgaagaa gcaaccgttc
     6841 caatttgtac gtttacgata aaaaattcaa atgaacaaga tggaagctat ataaaattat
     6901 cagattttaa aggtggaatg gaagttcaaa aaattaaaac gttagaagca attcatcagc
     6961 atggtgaatg cgattatttt tatagtacta atcaagacaa cttcaaaaaa atcccaggaa
     7021 tgccgattgc ttactgggca agcgataacg taatcactga ttttgctcaa ggaaaattaa
     7081 ctaacgatgt tgcagatgca aaacaagggt tggcaaccgg aaataacaat aaatttttgc
     7141 ggtattggtt tgaagtagaa tttaacaaaa taaagtttga tgctaaaaca ttagaggacg
     7201 ctaaaaagtc tagaaaaaaa tggtttccta caactaaagg tggtcgtttt agaaaatggt
     7261 atggaaacaa tgaatacgtg gttaactggg agaatgatgg agatgaaata aaaaattatg
     7321 ttaatgaaaa tgggaagtta aaatctagac cacaaaatct taattactat tttaaaaagg
     7381 gaattacttg gtcgacactt tcatctggac aagtatcttt tagattgcag aatcaggcaa
     7441 tttttgaaac taaaggatct gttctgttct caaaggatat aactgacttt gaagaaatat
     7501 ttggctatgt aaactctaaa ttagttaatc actttttaac ttttatttct cccaccttgg
     7561 attaccatga aggaccaatg ggaaaactac cttttcttaa agttacatct gagagaaaat
     7621 taaaaaaaat aagagaaaaa gtggatgaaa atatcgatat agctagaaaa gactataatg
     7681 ctcttgaaac gtcatacgag tttagaagaa acattttgtt aagttatatg tttaaaaaag
     7741 atctctcaga ggcatttaac tgtctaagta ggcagttggt taatcaattt aatactctaa
     7801 aatcgaatga agaggaactg aacgacatat tcattaatca ttattctctt gaaaaagaat
     7861 taacaaaaga ggttcaagat gaatatatct ctgcaaggtt acctgataag gcgagggaaa
     7921 ttaaggattt tatttcttat tcaataggtt gtatcttcgg tcgttactcc ctagacgaag
     7981 atggtctcat cttcgctggc ggcgaatggg atccttcccg ctatcaaaaa tttaaacctg
     8041 atactgataa tgttttactc atcaccgatg atgagtattt caaggatagc caaattgaca
     8101 ttgtcaatcg tttcattgat ttcgttgaga ttacttttgg taaagaaacc cttgaagaaa
     8161 atctccagtt tatcgctgac actttaggtg gcaaagggac aagtcgagaa attattcgtc
     8221 gttacttcgt acaagatttt tacaaagacc atttaaaaac atactccaat cgaccaattt
     8281 attggcaatt ggactcagga aaacaaaatg gctttaaagc gttaatgtac ttgcatcgct
     8341 atacaccaga tcaattagga aaagtacgta ctgaatacct acacgaacta caaaaagcgt
     8401 atgacaatcg aatcgaattg cgtcagcaac aaatttcaac aagtgataac ccaaaagaaa
     8461 gaaatgcaat gacaaaagaa attgtaaaga ttcagaagca attaaaagaa gttcgtgagt
     8521 atgacgagaa gttgggtcac ttagcattaa aacgaattga attagactta gatgatggtg
     8581 taattgtcaa ttatgataag ttgcagcgtg atcctaaaac cggcgagaaa ttccaaattt
     8641 ttgcaaaagg ggtcaaagaa ccaaaaaaat agttatctaa gaaagttgtt ttctaacaac
     8701 tttctttttt attcttaaat tgcgtgcgaa attatccaaa ttatgtcaat ataaggggta
     8761 tagaaagaga acgattaggt gagattgatg acagatataa atacgcaaca aattgaagaa
     8821 aaattaaatc aacgttttcc taattatgga tgtaggaaaa tcattttttg gtttgattca
     8881 aatcaggatt ttcttgaaga aattgactca ttggtcattc aaaatgcaaa aatctatcga
     8941 ttagaaaagg acgcacaatt taaaactaag cgtttattgg aatatgaaga tcccgaaact
     9001 aactatttaa tctatgcgcc atttcctcgt tgggatgata aagatgaaga taatcatttg
     9061 ttgagtgtat tgaattattc agaggaattt agtgcagacc gcttagcgat tatcatgaat
     9121 gaattggcta ttccacttag atttcatcag acagttaaac agtatcgtaa tttctttaat
     9181 gcaaaggatc gcatgagaag ttttggtgaa tttagtacgc atatgacaat taataaatca
     9241 gaaacgattg aattaatgat aatggctgtt ttgttgaaat cgaaaagtat tcgattaaat
     9301 gatttactgc gtgtagttct aaaaagcttt acagaaagta gggagaatcc tttaagggaa
     9361 cttgataagt atcagttaac agctaaattt tgggaattta ttcaaatgaa atttggcttt
     9421 acggatagcc agccaacatt ggaaaagctg acgatgtgtc tttatttgaa ctatttttat
     9481 tatcaaattg atcaagagat gccgaagaag ttcaaaggat ttgaaatact acatttgaaa
     9541 gcaaacatta ttactttcat ggatcagttt atgaatgata cacgttacat ggaaagcttt
     9601 gaacagctat ctaaaaaagt atatcaggct attgatggtg atggattatt agacagtata
     9661 gaaattgatg atctaattga agcagacgta ttttctgaga ttcatgcaaa aatattaatg
     9721 ttttatgcag aacgattaaa ggcttctgac actacaacga aaattgcagg acaaacaatt
     9781 tttgatagtt taaagcagcg cgaaaaaatg catttcgcat cggattatat ttatgagtat
     9841 caattattga aacatgctta ttatcttgtg gataaaaaca gattgtgctt gccgatgaac
     9901 atggataatt tgctaactca atatgagaag gaaatgtatt gggttgatac gcattatcgg
     9961 aaatttattt ggaatagtga tcatatagaa gaaaagcaaa aatatggcca attgtatcga
    10021 ttagttgaag caaattattc gaagtttctt gatcaatcag gacaaatttg gaatcaaact
    10081 tttgaattta agaatcgtcc atccattcga aaattttata atcaagctgt aatgaaacgc
    10141 tctgttaaaa ctgtagttat tatttcagat gcttttcgat atgagttagg gatgaattta
    10201 gaacgtaagt tagttagaga aaagaagtat tcaacaaaca tggctagctt tctttctgta
    10261 ttaccttcag ttactgaatt cggtaaagcc gccttattac caaacaatca actaacttac
    10321 aatgaaggaa cagaagtact gattgatggg aaaaaaacga atggtttatc caatcgaaat
    10381 gcgattctcc agcaacgaga tgcaaatgct gtagctttaa attatgatga tgtggttaag
    10441 atgaataagg ctgaggtacg agaagtattt aatggcaaat cagtcattta tatttatcac
    10501 gatcaagtgg atagaacagg tgatcactcg aatgaaaatc gagtttttga ggcctgtgat
    10561 ttagcgataa gcgaaatttc ccgacttatt aatcgcttgc ataatgatgg cagtatctat
    10621 cgttttatag ttacggctga tcatggattt atttataaaa gaagccacgt tgaagaagta
    10681 gataagattg aaaatccatc tagaaatgaa aaagatcgtg tagaacgtcg ttttattctt
    10741 agtgaagaag aatacgaaat aattggtacg aaaaattact ctttgggaga ttctttagga
    10801 aatgatgaca ctagaaacat ttgtgtcccg attacttcaa gtatttttaa gaaagctggc
    10861 gggggacaaa gctacgttca tggagggtca tctattcaag aaatgctagt ccctgttcta
    10921 gaaattacgg tagccaaagg tagcaatgca aaggaaccag tagcaattga attaatgact
    10981 agcaaccgca gaattacagg attatcaacc acgttagaat tctatcaaaa aaatgcaatt
    11041 agtgatgttt atgaccccgc atctttctgg ctttattttg aagatgaata tggtgaacgt
    11101 atctcaaatg aagaaatcta tgttgcggat tcaaaaacag aagatgcaaa tcagcggttt
    11161 actaaatttg tttttgaatt tgtaaatc
//
LOCUS       DAZKCH010000086        10341 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000086 DAZKCH010000000
VERSION     DAZKCH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.087"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            196..345
                     /locus_tag="ACG84X_002343"
     CDS             196..345
                     /locus_tag="ACG84X_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFP9128172.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            356..1870
                     /gene="dltA"
                     /locus_tag="ACG84X_002344"
     CDS             356..1870
                     /gene="dltA"
                     /locus_tag="ACG84X_002344"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFP9128173.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            1867..3072
                     /gene="dltB"
                     /locus_tag="ACG84X_002345"
     CDS             1867..3072
                     /gene="dltB"
                     /locus_tag="ACG84X_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFP9128174.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            3117..3350
                     /gene="dltC"
                     /locus_tag="ACG84X_002346"
     CDS             3117..3350
                     /gene="dltC"
                     /locus_tag="ACG84X_002346"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFP9128175.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            3353..4621
                     /gene="dltD"
                     /locus_tag="ACG84X_002347"
     CDS             3353..4621
                     /gene="dltD"
                     /locus_tag="ACG84X_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFP9128176.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            4762..5844
                     /locus_tag="ACG84X_002348"
     CDS             4762..5844
                     /locus_tag="ACG84X_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFP9128177.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            5844..6647
                     /locus_tag="ACG84X_002349"
     CDS             5844..6647
                     /locus_tag="ACG84X_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFP9128178.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            6717..7457
                     /locus_tag="ACG84X_002350"
     CDS             6717..7457
                     /locus_tag="ACG84X_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFP9128179.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            7468..8472
                     /locus_tag="ACG84X_002351"
     CDS             7468..8472
                     /locus_tag="ACG84X_002351"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFP9128180.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(8517..>10341)
                     /locus_tag="ACG84X_002352"
     CDS             complement(8517..>10341)
                     /locus_tag="ACG84X_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128181.1"
                     /translation="YNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSPADSNQMK
                     EIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLLIKGNHQW
                     ITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGLPPKF
                     YLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILLSCFA
                     LALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYGIFCT
                     FQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNRFYVACTP
                     WIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNTDKDRRQV
                     DFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVEKILE
                     EAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDDLAQLLIH
                     ALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGITEELDDQE
                     RFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         3325 a         1706 c         2086 g         3224 t
ORIGIN      
        1 acaacctctt tattttttat attttttaaa agtacgagaa attataaaga aaaaagcagt
       61 gatttgatgt gctattttta taaaagctat gtgacaaaac tgttagtaaa aaaacggttt
      121 ctgtaagcta gacacatgtt tctttttgtc aaaattagtt acactttgtg tgaggttata
      181 tgaggaggga atccaatgaa caaatggcgt tctaatccaa aattgaatta ttggggaaaa
      241 ttcatcattc gaacaatttt ttatagtgca gtactgctgt tcctgattta tctgtatcac
      301 tataaaaata ttcaaggagg aacttttatc tataacgaat tttaggagga agagtatgga
      361 aatcaaaacg attattgaag caatcgatga ttggggaata aatgaacctg atcgagttgc
      421 ttatcaggcg gatgagacgc atacttttgg tgaattgaaa caagcatcag acgcacttgc
      481 ttattattta gaaaaaaagg tagaaggcga tggaccaatt gtcgtttttg gcaatttgga
      541 gtttgaaatg attgtctcat ttctaggggt tgtcaaatct ggccatgcct atttgccgat
      601 tgaagagcat acacccaagg agcgtatcct atcgatcttt cgggtggcta aaccatctat
      661 ggtcatcagt atcggggact ggatagaaga tattccttcg gttcctgtca taacaaaaaa
      721 agaatttcaa gaaatcaaga agataccagt aggattttat cccagaaata gcgtaaaagg
      781 tacagaaaat ttttatatta tttttacttc tggtactact ggagaaccaa aaggcgtaca
      841 aatcagtcat gataatctag tcagctttgt tcaatggacg atggaagact ttgggatcaa
      901 gcctggtatg catttcttag cccaagcgcc attttctttt gatttatcgg tattttctat
      961 ttatcctgca ttagtttctg gcggaatgct gaagccgtta aataaagcag ttgttcaaga
     1021 ctttcgtcaa ttattcgcga cattgccagc cttgaagttg aatgtgtggg tttctactcc
     1081 atcatttatg gatatttgct tgatggaacc tacattcaat ggagaaaatg tgccggaatt
     1141 ggacatgttt ttattttgcg gagaagaatt gacgaaaaaa actgcagaaa gtctacttga
     1201 tcgattccca aatgcacgga tatataatac ttacggtcca acagaagcaa ctgtagctat
     1261 ttcaagtatt cagattgacc agcatgtact agatagttat gaccgactac cgattggcta
     1321 cgtaaaaaaa gacacgaaag tttctattgt ccaagaaggt aaacctgttt caaaaggaga
     1381 aacgggtgaa atcattattg caggaccaag cgtatcaaaa ggttacctga acaatcccga
     1441 aaagacagct gctgcgttct tttgtcaaaa tgacttagca agttaccata caggggatgc
     1501 aggtagacta gatgaatatg ggcttttatt ttatgaagga cgtatggatc agcaggtcaa
     1561 attacatgga taccggattg aactcgggga tatcgaacat tatctgctcc aagacaaccg
     1621 aatcaaacaa gctgtcgtcg taccaaaata ccaaggaaca aaagtacagc agctggttgc
     1681 ttttgtcgta ttagaaaaca aaacgaaaca gccggatttt cagttgacta aatctatcaa
     1741 agaacaatta ctagaagttg taatggatta tatgattcct cagaagttcc attatgtcga
     1801 tctgctgcct cagacagtta atggaaaaat cgatcgaaaa aaattaacag ctgaggtgaa
     1861 tcctgaatga tgttacctca tatgatccct tatgcagagc cgttttattt ttttctttta
     1921 gccattgcgc ttgtaccgat cgttctatct ttattgatat gggaaaaaag attaccagtt
     1981 tatcaatcag cagtgacact tttcttttta tttgtcagct ttggaggtaa ttattggcaa
     2041 cagggagcgg cgctgattgg gtatgttttg tggcagacga tacttgtatg gggctatttt
     2101 gtttatcggc aaaggaaaaa tcagacagga tggttttttg ccgccgttat tttagcgata
     2161 attccactgt ttttaacgaa agtgactcct ttttttgaac atggaaaagc atcgttactt
     2221 ggttttttag gaatctctta tttaaccttt aaatctgtac aaatgatcat ggaaataaga
     2281 gatggcatga tcaaaacata taagccattt cgttatatcc agtttctgct gttctttcca
     2341 acaatctctt ctggaccaat cgatcgctat aggagatttg aaaaagatca gctccatccg
     2401 cctgttcgtg ataaatatgt tgatcttttg ggaaaaggcg tccaaaatat ttttgtcggt
     2461 tttttatata aattcattat cggttattat tttggtcaag tactgcttcc tgtagtggga
     2521 cgcattgcct tacagcatgg tggtatttca tgggcattag taggttatat gtacgtgtac
     2581 agtatgtatt tgttttttga ttttgctggc tatagcttat ttgcagtcgg tacaagctac
     2641 atgatgggat atcagacacc aatcaatttc aataaacctt ttttatcatg gaatatcaaa
     2701 gaattctgga atcgttggca tatgacgctg tccttttggt tccgtgatta tgtatatatg
     2761 cgattgatgt tcttcatgat gaagaaaaaa ttttttaaaa gcaagatcgt aatgtcaaat
     2821 atcggttatt ttgctttgtt tcttctaatg ggtatatggc atggattgac gtggtactac
     2881 atcgtatatg gactgtatca tgcttgtctg atctgtctga cagatgcatg gatccgattt
     2941 aagaagaagc ataaagagca gttgccttct aacaaattta cgcatggctt agccgtattt
     3001 ttgacatttc aagcagtatg ttttagcttc ctgatttttt caggattttt agataaactt
     3061 ttttttagct aacgaatagt gacatattaa tttatataac aaaggagaaa aggaaaatgg
     3121 aagaacaaat tttatcaatc ttagaagaaa taacaggaac agatgaagta agaaaaaatc
     3181 gtgatattga tctatttgat gaagggttgc ttgattcttt agcatctgtt caattattag
     3241 tcgagctaga cggagagctg gatatccaag tccctgtatc tgaattcgag cgagaggatt
     3301 ggtgcacacc gaataaaatc attcaacaag caactgcatt gaagggttga gtatgaaaaa
     3361 gaaacttttt gctattttcg gcccggttgt tttagctgtt ggcttactgt ttgtgttttt
     3421 tacctcctcc tatcaagtag atatctctaa tccagaaacg attagacgtg cctcttcttc
     3481 catgtcagtg aacgtgttga aaggagatgc gataaaaaat tatgcattat ctgaaaaaca
     3541 atatattcct ttttttggct caagtgaatt aagcagaatc agtccatttc atccgtctgt
     3601 tctggcagaa aaataccagc gaaactatcg tccatttttg ctgggagcac ccgggacaca
     3661 atcgttaagc caatatatga tgatgcgttc tgcaggagat gctatgaaaa acaagaaagt
     3721 cgtctttatt atttctcctc agtggttcgt taaaaatggt gtaaaaactg attactttaa
     3781 tacgtattat tctgaacttc aaacatacga ctggttgttt tcaatgaaga aagtaacgcc
     3841 tgctgatcgc tatttagcta gaagattatt aactttctca aaagtaaaag agaatgatac
     3901 gttgacggcg attctgcaaa cgatcaaaaa agggaagcta cctttacctg aatctttgaa
     3961 tcagctgcgc agccaatgga acatgctgaa gagagaggat gaagtattca gcaatattgg
     4021 gttgaaagat cgacagcaaa aaatcgatca tgagtcaaaa cgattaccaa aacaatacca
     4081 agaaacagaa ttatccattt tagcaaatca aattggagaa cgagaaacga cgaataatcc
     4141 attcgggttg aaaaacgatt tttatacgca tcgtatccga gcccacgagc cagagctcaa
     4201 acagtcacaa aaaaattggg attatcgttt ttcgccagaa ttttctgatt ttcagctggt
     4261 cttggatcaa ttagcaaaaa accataacga agtattgttc atcatcccac cggttaacga
     4321 gaaatggagc gattataccg gactatctca agaaatgtta caaggatttg ccaaaaagat
     4381 caaatttcaa ttaaatagcc aaggattcaa tcgaatagct gattttgtca atcaagcggg
     4441 taccaactat tttatggaag acacgatcca tctaggctgg aaaggctggt tggctgcaga
     4501 tcaacagatc agaccgtttt tagaagaaaa tcatattact gctagtaagt atcatcttga
     4561 cgatgctttt tttagcaaat cttggcaaca tcaaatacca gataaactac aattaaaata
     4621 aagaaaacag gcgagtgttg ctcgcttgtt ttctttattt ttgaatattc tgaataaaag
     4681 ataaaaatac caagtttgcc tgaacaaaaa tcataagcaa tggtataatc acaatatgaa
     4741 tatagaaatg ggggaaaaca tttggataca aaagaagaac agctacttat tgatttaact
     4801 tctgcaaaag gagtacctgg aaatgaagaa gaggtaagag aagtattcag agaatatgcc
     4861 aaaccattcg ctgatgatat tttttatgac ggtttaggca gtgtgattgc caaacatggt
     4921 gctggcggag gccccaaggt ctttatttct ggacatatgg acgaagttgg ttttatggta
     4981 acaaaaataa ccgaaaaagg attcttggaa ttccaaactc ttggaggttg gtgggggcaa
     5041 gtcatgcttg ctcagcaagt tgaaatcaaa acacgtgaag ggaaaatcgt ccacggtgtg
     5101 attggttcca aaccaccaca tgttttaaca cctcaagtaa gaaataaacc ttatgaaata
     5161 aaggatatgt tcattgatat tggcgcatca agccaagaag aagccaaaga gtggggcata
     5221 cgtcctggag atatggtcac tccatatatt gaatacaaac gaatgaatgg cagtaaatat
     5281 ttactggcaa aagcatggga taatcgtatc gggacagctg tttctctgcg agtattagag
     5341 aatctatcta aagaagcaca cccaaatgtt ttattcgcag gaagcgatgt gcaagaagaa
     5401 gtaggcttgc gaggtgctcg aacaagtaca caccttgtaa atcccgatat tgcttttgct
     5461 ttagatactg gtacagcagg agacactcca ggaatgacac caaaagaagc agattcgatt
     5521 ttaggaaaag gcccacagat tttgattttt gatgcatcta tgatcccgca taaaaaatta
     5581 ttgaattttg ttattgatgt agcagaggaa atggatattc cattccaata tacagtgatt
     5641 tctggcggag gaactgatgc aggacaaatg catttgacaa gagatggtgt tccgtctgta
     5701 gccattaccg ttcctgttcg ttatctgcat tcccatacat cagtgattca tgaagatgat
     5761 tatttgaata cagtgaaact agtcacagaa ttagtgaaac ggcttgatag tgaaacagtt
     5821 gaaaaaattc ggagttatga ataatgaata atagaatacc tatttctgaa tatcggaaaa
     5881 aagcacgagt ttctttggaa aatcaatggg gaatcaatac ttggcttgtt ttcttatcta
     5941 taatatttac gagcgtcatc cagaactttt ttgacggttt cagtcctttt ccggaagaaa
     6001 gcatgcagca gcacttattg agttttctag tcgataattt acttttattc gcattcaact
     6061 atgcattgtt ttacattgcg ctagtagttg tacggggtgg cagaccaaaa agtaaccttt
     6121 tattttcagt tttccaaaga aagtattttg gttcgatact tggcatcaat ttgatcaatt
     6181 cagtcatcaa ctggctactc aacagtttaa tctttctgcc catgttttta atcagcggag
     6241 tgagtactta tatgcagctg cttttcagtt caaatgcggt acctacgggt gtcatgccag
     6301 aagattttct tgatatcagc tttgttttat cgatgatagg gatgattttt gtttcagcac
     6361 tcatcatgag tattgttggc ggtttattcc aatttgctgc atggacaaag ttcgactatc
     6421 ctgatttgtc ggttattcaa tgtttgaaat atggctggtt tttattgaaa gatagaattg
     6481 gtacgtatat tttgttgcag ctgtctttta tcggctggta tttgctagga gcaatcgctt
     6541 tgttcatcgg tcttttgtgg gtcattgttt atgtgaatgt gtcagttgca gaattttatg
     6601 aacaagcacg gattgaaaaa ggaggtccag acgcctattt tacttagcat gtaagcagtt
     6661 tattcatcaa aaaaataact tttgtggtag gataaatctt tgagggggaa tgtacgatga
     6721 aattaactgt tttaggatgc ttaggagcgt atccttataa aaatcaaggg acaacaggtt
     6781 atttgcttca atctgacggg ttcaatttgt tgatcgatgc aggtagtgct acgctgatca
     6841 aattacaaga acaccttgat ccacttgatc tagatgctgt gatccttagc cattatcatc
     6901 atgatcatat tgctgacctt ggtgtattac agtattactg gcaacttcat cctaagagaa
     6961 atccggagac attgctttca atttatggac acacaaaaga ttccattcac tttgaagaat
     7021 tgacgttgga aaatgtctca aaaggacatc cttattttga agctgaagaa ttaaaaattg
     7081 gtccttttct gattactttt atggaaacaa tccatccagt agtatgttac gccatgcgta
     7141 tcgtagaaga aacaacgggg aaagtattcg tatttacagg tgattcaggt tatttggaaa
     7201 gtttcgctga ttttgcgaaa gatgctgatt tgtttctagc agatacctat ctttttgaag
     7261 gaaatgaaca tcatcatgcc catttcactt caaaagaagc tggagaactt gcgaaatcag
     7321 ctaacgtaaa gaaacttgta cttacacacc tacctcagtt tggtgattta gaacaattga
     7381 aaaatgaagc gcaaaaggca gcaggcaaag ggattgatat agaacttgct gcagttgaca
     7441 aagtgtttaa catttaggag gaagaacatg atttttgtac caaatgaaaa ccacgaccca
     7501 agaatcaatt tagcaattga acaatatttg ctgcaagaaa tgcctttaga tgaacctatt
     7561 ttgctctttt atatcaatga accttcaatc atcatcggca gaaaccaaaa tacgcttgaa
     7621 gaaatcaatc gagattatgt ggaagaaaat ggcattcatg ttgtccgtcg cttaagtgga
     7681 ggcggagctg tctaccatga ttttggaaac ctgaacttta gttttatcat gcctgatgat
     7741 ggggattcat tccgtgactt tgcgaaagta acacagccaa tcatccaagc acttcatgaa
     7801 ttgggtgttg ctggggcgga attgaaaggc cgaaatgatc tagtcattga tggcatgaaa
     7861 ttttctggca acgcgatgta tgctaccaac ggtcggatgt ttgctcatgg aacaattatg
     7921 ttcgactctg atatcaatga agtagtcaat gcattaaaag taaaaaaaga caaaatcgaa
     7981 tcaaaaggaa tcaaatcgat ccgttctcgt gtaacgaata tcaaaccatt tcttccagaa
     8041 gaaaagcaaa aaatgacaac agaagaattt cgtcaagaaa tcttgttgaa aattttcggc
     8101 gtagagtcag tagaagaagt aaaaacgtac gaattgactg atgaagattg gaaaaaaatc
     8161 aatcgaatct ctgaggaata ttatcgaaat tgggattgga attacgggaa gtctccagat
     8221 ttcaatttct ctcgccaaaa acgtttttct atcggttcga ttgaagtcca tttgaatgtc
     8281 tcagaaggaa tgatcaaaga agcaaaaatc tttggcgatt tcttcggact aggagatatc
     8341 tctgacgtgg aaaaaaaatt ggttggacag aaatatgata aagcatctct atcaaaaata
     8401 gtcagccaaa ttgatgtgaa gaaatatttt ggtgcgatag aaccagaaga attgcttacc
     8461 ttactttatt gaaaataaaa aatagcggaa tccacatata tggattccgc tattttttat
     8521 acaggattcg ggtaatttcg agagagttga acagtgatcc gatcaatgaa agtatctttt
     8581 tcctgcgtta gtgttcctgt gtaacgatcc gctacgtctt tcatcatcat taagtcaaaa
     8641 cgttcctgat catctaattc ttctgtgatg cctcgactaa ataggtttgt atcgtaatgt
     8701 gcactatgtt cgcaacaaat gacgaaatgt tcctcttgtt cgtgtatcga caaataaatt
     8761 tttcgataca gtggattttc gatggcatga gtttctctaa aggaatgctc taaagcgtgg
     8821 atcaaaagtt gagccagatc gtcatcgttg ataggaagtt cttcgggaag atctgcttgg
     8881 aaggttatct gaatattccg tttggcagct aacttctggt aacgcgctaa gataagattt
     8941 gtcacctggt ggttgcaaaa agaacacagc atttcgaaat tttttgcttc ttctaatatc
     9001 ttttccacat agtttttagc ttttgtttgg tccgtatgca ttaaatcttg cagattctcc
     9061 atctcttgga caaattccag gcgaagtgta tttacttctt ggatatgctg tcgaagctgc
     9121 tcataatgtt gctccaacaa atcatttttg atttttaaga aatctacttg tctccgatct
     9181 ttgtcggtat ttaagatgtg atcgattaga ttgtagctga taataacgat tagaatgata
     9241 atatataaaa tcgtagacca attgatcgtt gtttgataga tacctaatgc cgtttggatg
     9301 taaatcaagc aatggataat ggctaccaag acgatccaag gtgtacaagc tacataaaaa
     9361 cggttattct tatatgcttc gccaatgcat gcaagtgaag tgactaaagt gcttataaca
     9421 ctagcaatat tagcaatcgg cattaattca ggaagttctg caggagtaaa agttgcataa
     9481 agcagaacgc cgataaaaat caaaagttgg aacgtacaaa aaattccgta ccatttttta
     9541 tagtaaaaca ttcggctcca atagtagcag atgatgaaag ctgacgttaa gataataaat
     9601 aaatgagata aaaaagaatg aacgaatggt tcaaaaagaa taccacttaa aatatcttct
     9661 gatacagctt caaatcctaa tgccaaagca aagcaactta agagaataag tgagtattca
     9721 agacgttttt gtttatacat caagtagatc gtatagaaaa aggtccctat agcgataaaa
     9781 acagcgatta tcatcgtcaa tacttgcggc actgattgtg aataaataaa actaatcaat
     9841 ggtccagttg ttcctagata aaatttcggt ggcagtccag catagttctg ataaggagat
     9901 gagactgtaa gggtcaattt ttttccgata taatttgctg gtaaatctat cacagccaat
     9961 gagagtccgg gattgctttc ttcctgataa tctttccgtt ggtataaaat cttttcgcct
    10021 agatatacag taatccattg atggtttcct ttgattagta aatttgcttc gtccaacggt
    10081 ttttcaagtg tcgtttccat aatgaatgtt tcgtctttat ccacggtagg aatcgtacga
    10141 gtgtacttgc tgtcaaactt aaaatcagga tcatcttttg tatagaaaac ccacgaatct
    10201 tttatttctt tcatttgatt gctgtccgca ggagaaaaaa taaaataaaa gaaataagca
    10261 attcctgtta aaaataacaa tgataatata atgattatgc tccactttat acgtaaataa
    10321 aaagattctt ttttattata t
//
LOCUS       DAZKCH010000087        10308 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000087 DAZKCH010000000
VERSION     DAZKCH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.088"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(25..267)
                     /gene="acpP"
                     /locus_tag="ACG84X_002353"
     CDS             complement(25..267)
                     /gene="acpP"
                     /locus_tag="ACG84X_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFP9128182.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            complement(389..1390)
                     /gene="plsX"
                     /locus_tag="ACG84X_002354"
     CDS             complement(389..1390)
                     /gene="plsX"
                     /locus_tag="ACG84X_002354"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFP9128183.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            complement(1439..3475)
                     /gene="recG"
                     /locus_tag="ACG84X_002355"
     CDS             complement(1439..3475)
                     /gene="recG"
                     /locus_tag="ACG84X_002355"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFP9128184.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            complement(3592..5274)
                     /locus_tag="ACG84X_002356"
     CDS             complement(3592..5274)
                     /locus_tag="ACG84X_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFP9128185.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            complement(5326..5688)
                     /locus_tag="ACG84X_002357"
     CDS             complement(5326..5688)
                     /locus_tag="ACG84X_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFP9128186.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            5958..6146
                     /gene="rpmB"
                     /locus_tag="ACG84X_002358"
     CDS             5958..6146
                     /gene="rpmB"
                     /locus_tag="ACG84X_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFP9128187.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            6384..9053
                     /locus_tag="ACG84X_002359"
     CDS             6384..9053
                     /locus_tag="ACG84X_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFP9128188.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(9508..10254)
                     /gene="truA"
                     /locus_tag="ACG84X_002360"
     CDS             complement(9508..10254)
                     /gene="truA"
                     /locus_tag="ACG84X_002360"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFP9128189.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
BASE COUNT         2801 a         2227 c         1853 g         3427 t
ORIGIN      
        1 atccttcttt gcttttattt gaaattattt aagatggctg ctgatataat ctactgcgcc
       61 accgactgtt tcaatttgtt cagcgtcttc atctgaaatt tccgtaccga attcatcttc
      121 aagctctaaa acgaattcca taatactaat tgaatcagct tttaaatcat ctttgatgtt
      181 caattcatcc gtcactttat cggtatctat ctcaaaatga tttgaaataa ttttcgctac
      241 tttgttaaat acttcttcgc gagtcaactt tttcacctcc aagaatcata cacttgtcaa
      301 ttacctacac catggctaat tttactggca tttttcagga atgtccacct ttttttcaat
      361 ggaacggatc gcttcagata tccaaatact attcttcgct tttttcaaat tgttcgacta
      421 attgtccaac tacatctgtc tcaagcattg tgtggatttg gcggatcgta tagcgaacag
      481 catcggggcc tgttgctcca tgagttttaa tgactggtgc tttcaagcca aacaaaacgg
      541 caccgccatg tttggaataa tccatttctg ctttcaaaga acgtaagccg tcttttaaaa
      601 gcatagcgcc catttttcct ttgatccctt catttagaat agcagatttt aatagattca
      661 tcatattcat tgctgttcct tcaatagatt tcaaaacagc gttgcctgta aatccatctg
      721 tgaccactac atcagccaca ccattgagta gctcacgagc ttctacgttt ccaataaaat
      781 tcaagcttgt ttcattctga aggagttcat aggctttttt cgtcacttca ctaccttttg
      841 ttgcttctgt tccgttgttt aagagtgcga cacgaggacg tccgatacct cggactttac
      901 gtgcataaaa agaacctaaa ataccgtatt gcaacaaatg ttctggtttg ttttctgcgt
      961 tagcgccaag atccagcata tcgaaaccgg caccttcttt ccctactact ggcaaggtag
     1021 acatcaagcc agggcgttcg atatttttga tacgtcctac gatgaacaac cctgctgcta
     1081 gtagcgcgcc tgtattccct gctgaaaata cagcatctgc ttcaccgttt ttcactgctt
     1141 gtgcagcaag gaccattgat gcagtctttt ttcgtcgaat tgcttttact ggctcatcat
     1201 cactattgat tttttcgtct gtatggataa tcgtgatgtt tttttcattt gttaagtatt
     1261 tcttgatttc tgcttctttt ccgtaaagta agaattctac ttctggaaaa tcttgctgcg
     1321 ctaaagccac gccttctaca attgcttgag gtgcgtgatc tccgcccatt gcatctacgg
     1381 caattttcat tgtttccact cctttttccg tcatcagtat aaagtatagc acagtctgct
     1441 aatcgaaata acgattatcc tgattttcta tttggaggct ttgcgctaaa ggctgatact
     1501 caggaagcat ctgccaatcc tttatttgcc aaagggctgc agcctcttct ctggctacct
     1561 ccaaaacatt tccatccgtc accaagtcag caatcgcaaa ttgaggcaga ccagattgac
     1621 ggaagccaaa tacttcacca ggaccacgta attccagatc tttttcgctt agtacaaaac
     1681 cattggtggt ctctgtcatg attttcatcc gttccacacc tagttcattt ttaggattag
     1741 caactaagat acagtaggaa gcatcacttc cgcgtccaac acgtccacga agttggtgca
     1801 gctgtgccaa tccaaatcga tccgcatcca tgatcagcat gacggtcgcg ttcggcacgt
     1861 ttacccctac ttcaattaca gtagtcgaaa ctaatatctg catctggttg tctttgaagg
     1921 cttccatgat tacttctttt tcctgattct tcattttacc atgtaacaag ccaacttcat
     1981 attttggtgc aaatagttca cgaagttttt catagatttc cactgcattt tttacatcta
     2041 atgcttctga ttcttcaatc agcggacaga tgacatacat ttgatgtcct cttgccagtt
     2101 cttttttcgt ccaatccagt acactgtcca attgaggtgt tcttacccag cgtgtttcga
     2161 tcgggatacg tccagctgga agttcatcaa tgatagatac atccatctca ccatatgctg
     2221 taatagctaa tgttctagga atcggagtcg ctgtcataaa taagacatct ggtcgccagc
     2281 ctttttcacg aagtactttc cgctggttca cgccaaaacg gtgctgctca tccgtaataa
     2341 ctagacctaa attctgaaat tcgactccat cttggatcaa tgcatgtgtg ccgatcacga
     2401 cgttaatttc cccttgctct agtttttcaa ggagctcacg tcgttctttt gctttcgttg
     2461 accccgtaat caatgcgatg gttacttcat tgggatcaaa cagctgttgc aagctttcca
     2521 tatgttgttg tgccaagatt tctgtaggca ccatcaacgc accttggaaa cctgctgtaa
     2581 cggtagcgta taacgcaatc gcggcaacca ctgtttttcc gctacctaca tctccctgca
     2641 aaagtcgctg catatgctgc ggactgcgaa gatcccgaca gatttcattc gttacacgtt
     2701 tttgtgcatt tgtcagttca aaaggtagct tttgagtaaa ttgtttcaat ttttggacat
     2761 cataaaggat ctccaaacca ttcgtttctg ctttttctgc ttttttcaat ccttgaagac
     2821 gcatttgaaa taaaaagaac tcttcaaaaa cgacacgtcg tttggcttga tggttttctt
     2881 cgtggtcttt tggaaaatgc atacttctta cagcagaagc tcggtcaagc agtcgatatt
     2941 tctccacaag gttgtttggc agattttctt caatcaatgt gccgtattct tgaaaccctt
     3001 ttttgattag atcaactaat gtcgtttgac gaattgattt gttgacgtga tatatcggcg
     3061 aaaagtcatc cattgtttga gaacctaaaa tcttcatccc gttcaaggct ttacgctttg
     3121 catcccattt accgtatacg gcgatttcct ccgataaaat gactttttct tttagataag
     3181 gttgattaaa aaaagaaacg ttgaacacat catgttcttg catcatacga aattgcaatc
     3241 ggcttttttt ataaccaaat cgattcatca caggaggcga gactacgatt cctttcaaag
     3301 taaccttttc ttgatcctgg atctcgttta gatttctttc ctgaatatct tcgtagcgaa
     3361 aaggataata agtcagtaag tcttcaatcg tttggatgcc caagctggca agactagctg
     3421 ctcttttttc tccgactcct gccagcatag tgattggatc atctaaagaa cgcataaatt
     3481 tttcctccct cctttaacaa aaaaaggact tggtcagcga tcatacctga tcactaaccg
     3541 aaggcctttt atgaatgaat actgtgttag aaagatattc tgacacagaa attattcagc
     3601 agaaaataga taaggataga caggctgatc tccttggtgg atctcgattt ccaaatcagg
     3661 atgtttttct gttagtttct cagcaaattc atttgcttgt tcaactgttc cttcatcacc
     3721 tgccaagatc gttacgatct ctgtgtcctc attgatcatt tgttctagtg tacttaacgc
     3781 tgttgctgtg atatctgggt tagagatcag gatttttcca tcgatcatgc ccaaaaagtc
     3841 tccttctttg atctctacac cgtcaattga ggtatctctg atcgcgtgag tgacttgacc
     3901 gctcacaacg ctagacaaca tttctgtcat cgtttctttg ttttcttcta aagaagcttg
     3961 atcattgaat gaaagcatag ctgtcaatcc ttgggaaatc gttcttgaag gaacaactgc
     4021 tactgggata tctgctactt ctgctgcttg atcagctgcc atgaagatgt tcttattgtt
     4081 tggcaagaca atcactttat ctgcgtttac ttcttgaatc gctttaacaa tgtcttccgt
     4141 acttggattc attgtttgtc caccactgat aacataatta gcgcctaaac tttcaaacag
     4201 ctcttggacg cctttaccag cagcgatcgc tacgatacca tacgggatac gtggtatttc
     4261 ttttttcgca aactcgttca cttcttcatc gtgttccaaa atcgtctcat gctgcaagcg
     4321 catgttgtcg actttgattt tgactaatga accgaatttt tgtccataat tcaagacttc
     4381 tcctgggttt tctgtatgca cgtggacttt gatgatctcg tcatcattga ccacaagtaa
     4441 agaatctcct ataccatcta aatagttacg gaattcttcg taatcgaatg tactatcgac
     4501 tgtaggtcct tctccgattt ttaccatgat ttctgtacag taaccaaaat ggatatcttc
     4561 tgtcgccatt tgaccttgga cactgcgatg atgttctgca ttgaccatat catccatttc
     4621 tgctggagaa ggttcatatg tttcatccgc ttggaattct ccattcaatg cacttaaaaa
     4681 gccctcataa acaaacagca gtccttgccc tccactgtct acgacaccga cttcttttag
     4741 gactggaagc aagtctggag ttttagctaa agcacgcttt gctcctttta caacagctgt
     4801 cattacttca acgacatcat cagtactttt tgctttcttt tctccagctt tcgctgcttc
     4861 tctagctact gtcaaaatcg ttccttctac tggtttcatt actgctttat acgcagtttc
     4921 aactccatga gtgaaggctg cagcaagatc agaagcattt aatgagacaa catctggaat
     4981 ttgcttagaa aatccacgaa acaattgaga caaaataacg ccggaatttc cgcgcgcacc
     5041 catcagcaat ccttttgaaa gcattgctgc taattctcct actttttctg aggttgaatc
     5101 tactactgcc ttagctccac tagtcataga tagattcata tttgttcccg tatcgccatc
     5161 tggcacaggg aatacattta atgaattgac gtattctgca tttacttgca gacgattcgc
     5221 acctgcctgg accatttcct ggaactggct tgcacttatt tctgttacac tcacctagat
     5281 aatcctcctt cagatcgact gctgagttac cagccagtct cctgcctagt ctggcagtac
     5341 acgaacacct tgtacaaaga cattaactga attggcagtt acgcctaata atgcctctag
     5401 attgtatttc actttttctt ggacgttgcg ggaaacttca gagattttcg taccatagct
     5461 gataatcgta taaacatcta cagcaatacc attatcttct tggcggacaa ctactcctct
     5521 tgagtaattt tctttacgca aaatctcagt aatattatct ttaatttgat ttttgctggc
     5581 cattcctaca acaccgaaca catctgtcgc ggcgccacca acaactgttg caattacatc
     5641 attggtaatt tcaatggttc cagctgacgt ttgaattttt acagccatga atgagcctcc
     5701 ttaacgggta aaaaactccc atttttcttc tatcatattt tatcatagcg caacttgaaa
     5761 taaaaggcag ttacccaaag tactcaaaaa ccttgcaaaa tttcaggtat aaccttgttt
     5821 aatttacaat tattcttctc aattgtcaat tgtatctatg aaaatgtact tgcaaattcc
     5881 cattctatat gatatgttag tctggtatga gctgaattat tctattgctc caaatcaagg
     5941 caaaggagga aattaccatg gcaaaagttt gttactttac aggtcgcaag acaaaaagtg
     6001 gaaacaaccg ttcacacgct atgaactcaa caaaacgtac tgttaaacct aacttacaaa
     6061 aagttcgcgt tatggtcgac ggaaaaccta aaaaagtttg ggtgtcaact cgtgctttga
     6121 aatcaggaaa agttgaacgc gtttaattga atgatacttg gaccgttcag atagtgaacg
     6181 gttttttatt taataaaaat ttttaagggt gggacttttg attcctaccc tttttttgcg
     6241 tttatttttg ttatacgaac aaattatgaa gttatttatt ctaaatttta tttttttgtg
     6301 aaaactagac tctttttaag cagagaaaaa caaggatatg ataaactgaa tacaacttca
     6361 tagaaatttg gtggaaaata aatatgaaaa aaaatttaaa gtcattcttt agagaaaacg
     6421 gacgctacgc agcagctagt ttcctgattc cgtttttgat tttagcactt gtttatctaa
     6481 gtatcggaat ctatcctgga agcagcagaa gtattttggc aagtgatgcc ttttcacagt
     6541 tttctaattt tcatgccagc ttccgaaatg ttcttcttgg aaagcaaagt attttttata
     6601 catggaatgc ttctctagga ttgaattatt tatctttaat ttcttactat ctaggcggga
     6661 tcttcacgcc actggtgttc ttttttccaa accagatgat gccagatgca ctgtatgttc
     6721 tgactttgct taaggtcggc tgtgccggat tggctttttg gtttcttgca cgtacgttca
     6781 agattcctcg ctgggggcat gttgcactta gcgtcagtta cgcattgatc tcatttatca
     6841 ctgcacattc ggagatcatc atgtggctgg atgcattttt ttatcttcca ttagtgattt
     6901 tggggattca tcgtgttatg gatcttaaac ggccgaaact tttatttatc agttatttac
     6961 tcttgttttt atccagtttt tatatgggtt ttatgattgg cgtattttct ttcttatatt
     7021 ttatcgcccg tctattgaca aactggtcag aatataaaaa aacgattgtt ccttatggta
     7081 tcacttcttt actggcaggc ggcgcttcaa tgatcattgt attgccagca gtgctggatc
     7141 ttcggtcaaa tggcgaggca ctgagtcaga tcactacgtt gaaaacagaa gcgacttctt
     7201 atctggatct aatcatgaaa aatatgattg gtgtttatga cacgacaaaa tacggatcga
     7261 ttccgttcgt ttacgcaggt ctgctaccat tagtcctctg tctgttttat tttgccagtc
     7321 ggaaagtacc gttgaaaaat aaatttttgt acggcagtct tttcgccata cttatcgcaa
     7381 gtttttatct tgttccattg aatttgttct ggcatggtat gcatgcaccg aatatgtttt
     7441 tattccgtta tgcctatctg ttctctttct tagtgctcct gcttgcagga aaaggatggg
     7501 aaaagataga acaagacgat cgtgggctgt tgttaggaat cattttggtc gtagctgctc
     7561 tctttgcggt ggcatggggc atcaaacctg aaggaagcta cacctatgtg acgatgactt
     7621 cctttgtatt gacagtggtt ttcttaggga tttatgcttt tgctgtggga ttttatcagc
     7681 ataaaaaact ttcattcaat catctgagta tattgttatt attgatcatg tctgctgaag
     7741 cactggtcaa tacgaacagt atgatccatg gcattcttga tgattggaat tatgcttccc
     7801 gcagtttata tactgatcct tatcctgact tgaaagctct tgtaaatgaa acaaaaaaag
     7861 attccgactc gttttaccgc ttggaaaatc tggatccagt atctgcaaac gattcgatca
     7921 actatggtta cagtggtatc agtttgtttt cttctataag aaatcgtaat tcttcctctt
     7981 acctggataa attaggtttc cgttcaagag ggacaaattt gaatatccgt tataacaata
     8041 atactttgct gatggatggg tttacaggaa tcaaatataa catttctaaa aacgaaagca
     8101 cgttcagtaa atatggcttc cgccaagctg gtcaaagcgg cgactataca ctgtatcaga
     8161 atgtcaatgc attgccacta gcatttactg caccgttgtc cgttaatgat gttgagcagc
     8221 cagtgacaga taatttgacc agtcagacaa acttgatcaa tacattgtct ggtctaaatg
     8281 aacagtattt tacattctat acacctactt tgaagaatca gttgaatacg acgatcacaa
     8341 agacaacgac tggcgtcact tactcagaaa cagcagataa ccagccaaaa gagctcactt
     8401 gggaagtcca tgtgcctgca aatacacaag cttacttaag tttgttccca accaattttg
     8461 cgcaattaga aagttctagt gcgacgatca ctgtcaatgg tacatcgcga aaaacgcaaa
     8521 tcaacatttc tggtcaatac tatgatcttg gctattatcc tcaagagaca acagtgacat
     8581 ttactgcaag tttttatggg acgaaagaaa taagtttcat ggagcctaaa gtcgttggtc
     8641 tagatgttgt agcctatcaa gccgcaatga atcagatcaa agaaaaaggt gtcgaaatgg
     8701 aagccactgg cagaaaagct tctgggactg taaataccgc tgaagattcc atgttggtga
     8761 caactattcc ttatgacaaa ggatggaaag ctaaaattga tgggaaacca gtcaaggtca
     8821 gcaatttcaa agacgcattc ttgatgataa aagttccagc aggtaaacat actgtcactt
     8881 tcagttactt gcctgaagga tttacgatag gtgcaatcct ttttgtccta tgtattgcat
     8941 tgtttattct ttatgtctgg taccttgacc gcaatcgccc cttttatggc acgattgatc
     9001 cagcaataga agaacaacca cgaaacacac acagaagaag acgtagaaaa taaagaaacg
     9061 atggaacctg ttcagactgt ccgcaccaag ggcaatcaaa acaacgttcc atcgtttttt
     9121 ggttacagaa aaaataggta acaaaaagat gattcactta tcaacgcctc gtccacaagt
     9181 cacgatattc atcaaagatg agaagctgtt ttttgaaatt gctctttgtg actcagagtt
     9241 aaatgacagg ctcacgacct ctttcttaaa cggtgttcaa tcagctgacc ttcggtatta
     9301 gctcaacaaa cggcaaaata tgaggagcta ttttcccgtt tgtttctcta atactcaggt
     9361 caaaacgctg atttcacgac ctcttcctta aacggtgttc cagaagtagc ttcttcgaaa
     9421 ataagccgaa attttgcaaa attttgagaa gtaattttcg taaatacctt cttatttctt
     9481 gaagctgacc acttctatca taacctctta ttcatatttc acttcataca aataaagtcc
     9541 ttcagggtgt gctgtaggtc ctgctgcatt acgatctttt ttcgcaataa tatctgggat
     9601 actatcttca ggcaatcggc cattgccaat tttcaaaagc gttcctacta agatccgtat
     9661 catcttatac aagaagccat ttcccctaaa tgtaaacaac aattcgtctt ttgtttcatt
     9721 tacctccatc ttagcctcgt agatcgtacg tattttatcc tctatcgagc ttcctgatgc
     9781 acaaaaagag gtgaaatcgt gagtccctaa taaatcagga agcgcccgct gaattttttc
     9841 caaatcaagt gggtaaggaa aataacttgc ataatggcgt cgaaaaggac tgcgtggttt
     9901 ccctatatcc actcgaaatt gatacgtctt ttctttgacc aaatatcttg cgtggaagtc
     9961 ttctgaaaca atttctactt gtcttacagc aatatcctct ggtgactggg tatctagcgc
    10021 gaaacgcatt cgttctaacg gacgctcctc tggataatca aaatggatta cttgcccgat
    10081 cgcatgtact ccggcatctg tccttcccga accaaagacc gtgatttctt ttccatttgc
    10141 cattttttgt aatgtttttt ctacttcttc ttgaacagta cgcccatttg gctgtttttg
    10201 gaatccatta aaatttgttc cgtcgtacgc aatgattgct ttgtaacgta ccatgttttt
    10261 ctctcctttg ttcctaaaag gttatctgga ataatgattt ttctataa
//
LOCUS       DAZKCH010000088        10124 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000088 DAZKCH010000000
VERSION     DAZKCH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.089"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(46..366)
                     /locus_tag="ACG84X_002361"
     CDS             complement(46..366)
                     /locus_tag="ACG84X_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFP9128190.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPQH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(514..2748)
                     /locus_tag="ACG84X_002362"
     CDS             complement(514..2748)
                     /locus_tag="ACG84X_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9128191.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            3227..3493
                     /locus_tag="ACG84X_002363"
     CDS             3227..3493
                     /locus_tag="ACG84X_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFP9128192.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            3493..5220
                     /gene="ptsP"
                     /locus_tag="ACG84X_002364"
     CDS             3493..5220
                     /gene="ptsP"
                     /locus_tag="ACG84X_002364"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFP9128193.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            5384..6430
                     /locus_tag="ACG84X_002365"
     CDS             5384..6430
                     /locus_tag="ACG84X_002365"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFP9128194.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            6447..7670
                     /locus_tag="ACG84X_002366"
     CDS             6447..7670
                     /locus_tag="ACG84X_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFP9128195.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            7759..8646
                     /locus_tag="ACG84X_002367"
     CDS             7759..8646
                     /locus_tag="ACG84X_002367"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFP9128196.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            8732..8962
                     /locus_tag="ACG84X_002368"
     CDS             8732..8962
                     /locus_tag="ACG84X_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFP9128197.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(9019..9984)
                     /locus_tag="ACG84X_002369"
     CDS             complement(9019..9984)
                     /locus_tag="ACG84X_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFP9128198.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
BASE COUNT         3226 a         1786 c         2043 g         3069 t
ORIGIN      
        1 tttacttttg tcccacgctc tttaattatt atgttcaaaa tttgtttaca cggctaatgt
       61 agcgcctaat tcatgttttg gaatcgagat ttcaacaagg cctgccaatt cgattacttt
      121 gatttcatcc tcgtggtaaa cggcgtcttt gattttatct aagaaataat ttttagcatc
      181 ttcgatttct ttcggctgga ttttacgttt gtcattgatc agcagaattt cattatgttg
      241 aggggcttca gtgtagacaa tagtggtatt tccggctgtg tagaccttga ctagatgggc
      301 atcagtgttt tcaagctggt ttaatacaag acgggaatgg ctgtttgtta catttaccaa
      361 tttcatggcg ctcacctctt ttatgtattt ttaattgctt gtttctctta ttataatttc
      421 ttttttataa aatgaacagt attttgactt ttctgaaaaa agaatgagac ggcatttctc
      481 aaagaaatac cgtctcacgc tataaaactg gatttattca gccgtttctt cggctgattc
      541 tttagccaaa cgttctggtt tagaagtaac gatgattttt ccatctttat ccagttttgc
      601 tttcaactca tggatagaag ggtgatcaag ataaaattca gcgataccat cttcgatttg
      661 ttcttggatc gtgcgtcgaa gaggacgagc acccatagat ggatcatagc ctaagtcaac
      721 taatttttct ttgacattcg taggaacttc gatgtgaagt tgctgtgctg ccagcatttg
      781 gttgacatcg tctagcatta gtgtgacgat tgtcatcaag ttttcttttg ataatgcact
      841 gaattcgatg atcccgtcaa aacggttcag aaattctggt gtaaagtagt tgtttaattg
      901 gttcaataca gaacgagtaa caccttcgcg tgccgcacca aaaccaacgt ttgcttctac
      961 tttaccagtt ccggcattac ttgtcataat gatgatcgta tctttaaagc tgaccgttct
     1021 tccttgtgca tctgtcaatc gaccatcatc taagatttgc aagaacatat gcaaaacatc
     1081 tggatgagct ttttctactt catctaacaa gacaagactg taaggatttc tccgtacttt
     1141 ttctgttaat tgaccagctt cttcgtatcc gacataacct ggaggagaac caatcaattt
     1201 agagacacta tgtttttcca tatattcaga catatcgaaa cgaatcattg aatcttgtga
     1261 accgaatagt tcgtaggcaa gttgtttcgc aagctctgtt ttacctacac cagttggtcc
     1321 aacaaataag aaggagccga ttggacgatt ctgtttgttt aatccaacac ggtttcggcg
     1381 aatcgctttc gctactcgat ctacagcgtt atcttgtccg atgacatgag ctttcaagtc
     1441 atctgctaag tttttcagtt gtgtctgttc tttttctttt aattcaccca ctggaatacc
     1501 tgtccgttgt tcaacgattt tttccatatc tttttcggta atcacaggtg tttcctcttc
     1561 agtgagctga cgttctttca ttttttgaag tttattgatc tgatcgcgat aataagctgc
     1621 tttttcgaaa tcttcttctc gagaagctaa aactttttgt tcttctgctt cttgcagttt
     1681 tttctcgatt gttttaggat caacgatttg gatcgtcaag tttttcttag aacctgtttc
     1741 atctagcaaa tcgatggctt tatccggcaa gaagcgatct tggacgtaac gattggataa
     1801 agttgcggct gcttcgatgg cctcatcagt atattttaca tgatgatagt cttcataacg
     1861 tttttgcaaa cctttcaaaa tactgatcgt ttcttcgaca gttggttcat ctacccgtac
     1921 aggttgcata cgacgttcta aagcagcgtc tttttcgatg atgcggtact catttaaggt
     1981 agtagcacca accatttgca attctcctcg agctaaagct ggttttaaaa tattaccagc
     2041 atccatattt ccatcaccag cagaaccagc accgactatt tcgtgaactt catctatgaa
     2101 taggatcaca ttttctgctt gacggatctc ttcaatcaat ttttgcatac gttcttcaaa
     2161 ttgtcctcgt ataccagtac cttggactaa agatacgaca tctaaacgaa tgacttcttt
     2221 gtccattaat ttttgcggta catcaccatc tacgattttt tgtgctaaac cttcaacaac
     2281 tgctgtttta ccaacacctg gttctccaat caagacagga ttgttcttgg ttcggcgatt
     2341 taaaatttca atgactcgtt tgatttcgtc atcgcgtccg atcacaggat cgatatcacc
     2401 ttgtcgtgct tgttctgtga tattgattcc gtattctccc aataaacctt ctgtattgcc
     2461 ttgaggtggc tgaccaccat tgaagttgtt gtttccgcca aattgtgttg gtggtgtttg
     2521 ctcataattt ccttgctgtt gcatttggcg agacatggaa cggaaaagat cgtccaaact
     2581 gccaaatcca aatggatcat tttgggccat attagtcaga cctccatttt gttgattttt
     2641 gattttttga taacagctct gacagtaatc gagttgtgtc cgctgaccat tgacagtggc
     2701 atacaagtga atcgttgcct cattcttgcc gcagttttga caaagcatga atcattcacg
     2761 tcctttcaca aaaatgggta catccatatt ttacatctcg tttttcatga ggtaaaagaa
     2821 taacccctag ttttttaaga gatttatgag gtagaaaagg tgaaatctct attgaccatt
     2881 cctgaccttt gactcttatt atactaaaaa taaaaaggga agcaagtaat tcgtttcata
     2941 tgaaaacaaa gagggtcaaa ggaaagaatg ataaacgtca ggagaagaga aagcgacaag
     3001 aaaaaggaaa taaacacgtt tgttataaaa tgtgaagaaa aggatgaaaa agaatccgga
     3061 ataatttgaa tacttttatc tgaaattgaa tgaaaactgt tgtatctaac gaaaaaaaat
     3121 gttaatcttt acagatgaaa gggtggcatt tgttaggatt ctctgaatta ctaaaaaaga
     3181 aaaccctcac ataaaaacaa cactcactta aaggagaccg attaatatgg aaaagaaaga
     3241 atttcacgta gtagcagaaa ctgggatcca cgctcgtcca gctacactat tagtacaaac
     3301 agcaagcaaa tttaactctg atgtaaactt agagtataaa ggtaaatcag taaacttgaa
     3361 atcaatcatg ggcgttatgt ctttaggtgt aggtcaaggt tctgatgtta ctattactgc
     3421 agaaggtgct gacgaagctg atgcaatggc agcaatcgtt gaaacaatga agaaagaagg
     3481 cttatctgaa taatggttga aatgctaaaa gggattgccg ctagtgacgg tgtagccgtt
     3541 gcaaaagctt acctgctagt tcaaccggat ttaacattca gtaaggcaac agtagaagat
     3601 actgcggctg aagaagctcg tttggatgct gcattagcta aatctactga agaattgcag
     3661 caaattcgtg aaaaagcagc gcaaagctta ggtgaagcag aagcgcaagt atttgatgcc
     3721 catttgatgg ttctttcaga tccagaaatg gtaggtcaaa tcaagcaaaa tattaaagac
     3781 aacagcgtaa atgctgaatc agcgctaaaa gaagtaacgg atatgtatat cggtatgttc
     3841 gaagcaatgg aagataatgc ttatatgcaa gagcgtgctg cagatattcg tgacgttgct
     3901 aaacgtattt tagcgcactt attaggcgtt actttaccaa atccatcaat gatcaacgaa
     3961 gaagtggtcg ttgttgcaca tgacttgact ccaagtgata cagcacaatt agatcgcaat
     4021 tttgtaaaag cgtttgtaac agacattggt ggacgtactt cacattctgc tatcatggca
     4081 cgttctttag aaattccagc aatcgttggg acaaaagaaa ttactgctaa agtcaaagaa
     4141 ggcgatattt tggctgtcaa cgggatcgaa ggcgatgtaa tcatcgatcc tacagatgaa
     4201 caaaaagctg aatttgaaaa agcaggtgca gattacgcag cacaaaaagc agaatgggaa
     4261 aaattaaaaa atgcagaaac tgtcacagct gacggcaagc attttgaatt agctgcaaac
     4321 atcggaacac caaaagatct agttggtgtc cataataatg gtggagaagc agttggtctg
     4381 taccgtactg aattcctgta tatggattct ccagacttcc caacagaaga tgaccaatat
     4441 gaagcttaca aagctgtatt agaaggtatg gaaggaaaac ctgtagttgt tcgtacaatg
     4501 gacatcggtg gagataaaga actaccatat ctgcaattac ctcatgaaat gaatccattc
     4561 ttaggatatc gtgcattgcg tatcagttta tctgaacaag gcgacgaaat gttccgtaca
     4621 caaatgcgtg cattgcttcg tgcatctgtt catggtaatt tacgtatcat gttccctatg
     4681 gtagctacac tcaaagaatt ccgcgcagca aaagcgatct ttgaagaaga aaaacaaaaa
     4741 ttgataagtg aaggcaagga agtatctgat acgatccaag tcggcatcat gatcgagatt
     4801 ccagcagcag cagtcttagc agacaagttt gcaaaagaag tagatttctt ctctgtaggt
     4861 acgaacgatt tgattcaata cacaatggca gcagaccgta tgaacgaacg cgtttcttac
     4921 ttgtaccaac catataaccc atcaatttta cgtttgatca aaaatgtaat tgatgcagca
     4981 cacgctgaag gaaaatgggc aggtatgtgt ggagaaatgg ctggagatca aacagctgtt
     5041 ccattgctag taggtatggg tctagatgag ttctcaatga gtgcgacatc tattcttaaa
     5101 acgcgtagtt taatgaaacg cttggacaca gcgaaaatgg ctgaacttgc tgatcgtgca
     5161 ttgaaagaat gcgatacgat ggaagaagtc gttgaacttg ttcatgaata tgtaaaataa
     5221 acaacgtatc aaaagctggt gtggcttgta aaagagctac gccagttttt ttgttctttt
     5281 ttaagaaaac gtttttgtca gtaagaatag acaaaaatag ggcttaagtt tgagtgacag
     5341 tttgtaggct atgttatact atataagtga agggggacgt aaggtgaagg tattattata
     5401 ttttgaaagt gaaaagatgc ttgcaaaatc tggaatcggg cgtgcgcttg atcatcaaaa
     5461 acgtgctctg acggaagtcg gtatctctta tacactagat gaaaaagaag attatgacat
     5521 cctgcacatc aatacatacg gaatcaatag tcataatatg gtcaataaag ccagaagaga
     5581 aggaaaaaaa gttgtctatc atgcgcattc tacagaggaa gatttccgaa attcctttat
     5641 cggatcgaac cagctttctc ctatcgtaaa aaaatatctg gtaggattgt accaaaaagc
     5701 ggactatctg atcacgccaa caccttattc aaaacagttg ttggaaagct atggtatccg
     5761 tgtgccgatt caagctattt ccaatgggat cgacttagag aaatatcacc ctgatccaat
     5821 gaaagaacaa aagttcagag aatatttcaa actgtctccg gatcaaaaag taatcatttg
     5881 tgtcggtttg tttttcgaac gtaaaggaat cattgatttc gtagaaattg ctaagaagat
     5941 gcccgaatac acatttattt ggtttggtca tgttcccatg tactcgattc ctcggaacat
     6001 ccggaaaatt gtaaaagaag atcatcctga aaatgtcctg tttcctggtt acattcgtgg
     6061 agagatcata gaaggtgcgt attcaggtgc agatctattc tttttccctt cttatgaaga
     6121 gacagaaggg atcgttgttt tagaagcttt agcaagcaaa caaaacgtac ttgttcgaga
     6181 tattccagtg tataatggct ggttagaaga tagcaagaac tgctatatgg ggaagacaaa
     6241 cgaagaattt atccgactga tccaacagat taccaatcaa gaactaccga gtacgacaca
     6301 agccggttat caaacagcaa aagagcgaag tatcaataaa atcggtgaag aacttaaaaa
     6361 tgtatacgaa agtgtactga atgaaaaagt ctctagcaaa ttaaaaaaag taaatcaggt
     6421 caaggactag tttggaggcg aaaaacatga aaatcggctt ttttaccgat acctactttc
     6481 cgcaagtcag cggagttgct acatcgatca aaacattaaa acaagaatta gaaagacatg
     6541 ggcatgaagt ctatattttt acaacgaccg atcctaatgc ggataagttg gaaaaagatg
     6601 tgattcgaat gccaagtgta ccatttattt ctttcaagga tcgaagagtt gttgttagag
     6661 gcatgtggta tgcttatttg gttgccaaag aactagaact agatcttatt catacccata
     6721 cagaattcgg agcagggata cttgggaaga tggtagctaa gaagttgaaa atacctctga
     6781 tccatactta ccatacgatg tatgaagact accttcatta tatcggtaaa ggaaaagtga
     6841 tcaggcaatc ccatgtaaaa tacttgtcta gattatttgc aaatcatacg acaggtgtag
     6901 tttgtccaag tgaacgtgtt attgatacat tacgcagcta tggtgtaata gcaccgcttc
     6961 gcgtgattcc tactggtatc gacattgaaa aattcaaacg ttctgatatc actcagcagg
     7021 atatcagcaa attaagggag tcactaggtc ttcaggaaaa ccatttgatg attctttctt
     7081 taagcaggat ttcttatgag aaaaatatcc aagccttgat taatgggttt cctcaggtca
     7141 tctccgctta tcctaacgcc agattagtta tcgtaggaaa aggaccttat gtagaagagt
     7201 tagaggaatt gatctcagaa ctgcagttag aagaatttgt gcagttcaca ggagaagtgg
     7261 acaacaatga tgtagcactt tattataaag cggcagatta ttttgtcagt gcttctactt
     7321 cagaaacaca agggcttact tatacagaag cgatggcagc cggaacacct tgtgtcgtgg
     7381 aaggaaatgc ttatttgaac cgattgttcg atcatccttc attagggaaa acttttgaaa
     7441 ccgacgaaga ctttgcacca gcacttattg attatatttc cagtgaagtt cctaaagatc
     7501 caaaagtttt agaagctaaa ctttatgata tttcatctac acatttcggc gaagctatga
     7561 tcgaatttta tcaagacatg gttgtttatc atgaagaaga gatgcgaaga aaagaagaag
     7621 aagactcgat tgaacgaatc aaaataaaat taaattcatt taaaagataa aattcaaaca
     7681 ttttttatga aaaaatcctt gtttctagcg tatactagca tagaagcaag gatttttgat
     7741 ttttaggagg tcgaaaaaat gaaacttggt tttatcggaa caggcgtcat gggaagtgct
     7801 gtcgcacgcc atctactaga agcaggacac gaagtagctg tctataatcg gacaaaagca
     7861 aaagctgatc ctttagtaac agaaggagct atctgggcag atacaccaaa agcggtagca
     7921 gaacaaagta atattctctt tacaatggta ggttacccca aagatgtaga agaaatctac
     7981 tatggacagt cggggatttt ttctgcagat atctcaggac atattttagt tgatttgact
     8041 acaagtacac caagcctggc agaaaaaatt gcaaaaacag caaaagaaaa aggcgcagat
     8101 gcgttagatg caccggtatc cggtggtgac ttaggagcaa agaatggtac actgacgatc
     8161 atggtcggtg gagaagaagc cgtttatgat caagtactgc ctttattcaa agaatttggt
     8221 acgacattta cattgcatgg ttctgctggg aaaggtcagc atacaaaaat ggctaatcag
     8281 atcatgattg caggtacgat gacaggaatg acggaaatgc ttgtctatgc acaaaaaaac
     8341 ggacttgatt taaagaaagt gattgagacg ctttcaggtg gaagtgcagc taactggtct
     8401 ttaagcaatt attctcctcg tattttaaaa gaagattaca cacctggttt ttttgtcaaa
     8461 cattttatca aagatttaaa gattgcatta gaagaagcag aaaaaatgga tcttgtattg
     8521 ccagcaacta cccaagcatt gaaactatat gaagagttgg cagataaagg ttttgagaat
     8581 gacggaaccc aagctttgat caaactttgg tggcctgaag gaaaaatacc agaaaaaaaa
     8641 tcataaaaaa cgagtttttt tagagaaaat caatgcaagt aggctatgct tttgatacaa
     8701 tataacagaa ataagaaaag gaggacctcc gatgacacat tcacaattag tcgcaatcat
     8761 aaaacgactg gaggctatgg tcgagtcagc agataatgaa ctgcaagttc gccgttttga
     8821 aaaagaaggc gtagagaagt gtacagtaac ttatgataaa gcgaccgata catttgaatt
     8881 aactgaaaca gatactcatc agcaatacga atttgataat atcgatatcg tagcgatgga
     8941 aatctatgac ttaatccaat aaattttagg ataattgaca tttgaagttg aagatgccta
     9001 aaagaagccg agaagcaact aatttagttg cttttcagct tcttttttgt ttaacagttc
     9061 aatttcaaac tgttcttttt ctaatttttt gcggtaactg atcaagattt gtacaggatc
     9121 gatttcttct tttgacaatt gacgtttcaa agataaatga gcttctttct tttcataata
     9181 gaagtcagga gaaacgtcac cagaggtaat cattgtttct gcaagttgac cataacaaac
     9241 gaggtagtgc tttttctgac tctcatctgc tgctaatggc atgctgaagg tgagcgatgg
     9301 tgttcttaaa aactgctttt gttcctggat ccgtctaata aaataagtaa ctaattcgat
     9361 atctttttga agcataccgg ctttttcgaa attcaactga tagatgaaat gttgttgtct
     9421 ttttttcaag taagtcagta gctttttatt tcggccttga aacagccctt ggagttcctt
     9481 ttttttctgt tcaaaagtca tttcctgtag gtcaggaagc tggactcgca aagctaacaa
     9541 actaatttca gacaaccaag gcatttgata agtttcttcc attatacgca aaatagacgg
     9601 cattttttta tagagacgaa aaggcccgta tgttcgagcc gtaggagtat ctgttaatac
     9661 aaatccctta ttggtaatat gtacataatt ataattactg aaataattca tttgtcggtt
     9721 ataaaaagga cggtaatgtt ggatcaattg acactcgagc aataaagcat ctaattccgt
     9781 gtctactacg acgaaatcaa aatctgttat atgatgaatc atacgtaata ctttttttga
     9841 atgctgttta ttctgatgaa aatagctgct tactctattt ttgagccgtt ttgctttacc
     9901 aacatagatg accttaccat ctcggtcttt cataagatag acacccggca gcatggggag
     9961 agttttcatt ttttctttta acataggatc tccttttacg ctttgaataa aaagactata
    10021 acaaattttg aaataatgga caagttttag ggaattctat agttctgttc acagaaaata
    10081 ctttgataat caaaatatgt gagatagatg atttttctaa taaa
//
LOCUS       DAZKCH010000089         9950 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000089 DAZKCH010000000
VERSION     DAZKCH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.090"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(46..1557)
                     /locus_tag="ACG84X_002370"
     CDS             complement(46..1557)
                     /locus_tag="ACG84X_002370"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFP9128199.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(1879..3231)
                     /gene="murF"
                     /locus_tag="ACG84X_002371"
     CDS             complement(1879..3231)
                     /gene="murF"
                     /locus_tag="ACG84X_002371"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFP9128200.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(3384..4460)
                     /locus_tag="ACG84X_002372"
     CDS             complement(3384..4460)
                     /locus_tag="ACG84X_002372"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFP9128201.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            4656..6401
                     /locus_tag="ACG84X_002373"
     CDS             4656..6401
                     /locus_tag="ACG84X_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFP9128202.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(6681..7118)
                     /locus_tag="ACG84X_002374"
     CDS             complement(6681..7118)
                     /locus_tag="ACG84X_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFP9128203.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(7102..8475)
                     /locus_tag="ACG84X_002375"
     CDS             complement(7102..8475)
                     /locus_tag="ACG84X_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128204.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(8797..9285)
                     /locus_tag="ACG84X_002376"
     CDS             complement(8797..9285)
                     /locus_tag="ACG84X_002376"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9128205.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(9307..9909)
                     /locus_tag="ACG84X_002377"
     CDS             complement(9307..9909)
                     /locus_tag="ACG84X_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFP9128206.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         2913 a         2119 c         1798 g         3120 t
ORIGIN      
        1 aaaaatgaaa gtttctctta aaaaagagaa actttcattt tatgtttaat cgttatttga
       61 acggattaca aatccgcgtt ttttatcatt gtgacgttta ccgccatctt tttggctgtt
      121 attatttttg ctataaccgc cttttgattt gtttccacga taattaccgc cgtcacgacg
      181 attacggttg tttccgccac cacgtttgcc atttttattg tatccttttt tctgcattgg
      241 caatgggcgt tctggtgtga tcttcactgg cactgcatca gctggatctt ttgctgtcgt
      301 ttttagcaaa agtgcaacta aatcttgtgc agaatattct tctaataatt tatctgctgt
      361 ttgcaggtat ttatctagac cattttctgc aagttttgtt tcgatttgtt caactgcagc
      421 acctaattga cctttgaatg cttctttttc ggttggtgga cgtaaagtcg tcatccgttt
      481 tttcgtcaag ttttcaatca catgcaagta gtccatttca tttggtgtaa cgaaagtcac
      541 agacataccg ccttttccgg cacggcctgt acgtccgata cggtgaacgt agctttctgg
      601 atcttgaggg atatcatagt tgtacacatg agtgacacct gaaatatcta atccacgtgc
      661 agcaacgtct gtcgctacaa ggatatctaa atgaccgctc ttaaatgaac gcaatacgct
      721 cattcgtttt tgttgagaca aatcgccatg gattccttct gcacggtaac cgcgtgcttc
      781 taatccgcgt gccaattcgt ctacacggcg ttttgtacgt ccgaagacga ttgttaattc
      841 aggtgtttga acatcaaaca agcgagtcat gatatcgaat ttttcgtatt cttttgcgcg
      901 gacatagtat tgatcgatca agtcagctgt catttctttc gctttgatct tcacatgatg
      961 tggatttttc atgaatttaa cgccaatatt cttgatagct ggcggcatcg ttgctgagaa
     1021 aagtaatgtt tgtctttgat caggaacttg tgaaatgatt ttttcgatat cttccaagaa
     1081 gcccatattc aacatttcat ctgcttcatc caaaactaat gtttgaacgg ttccaagttt
     1141 caatgtgtgg cggttaatgt ggtcaagcat acgtcctggt gtacccacaa cgatatgtgg
     1201 acgatctttc aagccacgga tctgacggcc aatatctgct ccgccgtaaa cggcttgtac
     1261 acgtactttt ttgtcgcgcc ctaaacgata taattcttct tgtgtttgga tagctaattc
     1321 acgtgttggt gcgataacta aaccttgtaa ttcgtgacga tctggatcga ttttttctaa
     1381 cattggtaat ccaaatgcag ctgttttccc tgtacctgtc tgtgcttgtc caataacgtc
     1441 ttttccagct aatgctagtg gaatcgtttc tgcttggata ggcgttgctt cttcaaaacc
     1501 agcgcgttcg actgatttca acaattctgg tgataattct agttctttaa atttcaaatg
     1561 aatcctccta tatggttgtt aactgaggat gtagcttttt tgctaccccg tcgatttgtt
     1621 cggtcaaagt gtattgtttc tttttgacag tggccacgca cgtttttatc cattcttagc
     1681 ccctgtggca ccaccgaaaa atcactttgc gaagtttagg cattagaaaa gccaaacggg
     1741 tcgcgttcag ctttatcatt attatgacat ctggcttcaa caagttgttt ctatggcaaa
     1801 accagtccaa tttctcttca tctttcggca ataggttatt ctaacatagt ttttcgtttt
     1861 ctgcaagttt acagattttt atttcatttg ctgaagttgt tctaccactt caaataagcc
     1921 catgctgttg ctgcctttta gcataatact atctgttgct tcaagatttt gtttgatagc
     1981 atcaatcaat ttattctttt ctttttcaaa atagaacaca ggtagttggg ggtatttttg
     2041 gttcaattct tcttttagtg catgcatttg ttccccataa aggaaaatca tggcgaattt
     2101 ctcaggatcg atatgttcac tcatttgcgc atgcatattt aaagactctt tccctaattc
     2161 cagcatatct gctaacacag cgattctgcg tccttttgtt ggcagatttt taaaagtatc
     2221 taataccagt cccatggctg ttggatttgc attgtagaca tcgctcaaaa tagctgcacc
     2281 atttcctgcc gttagccatt cggttctgtt ttgagtgata gaaacatggg cgagcccttg
     2341 gcgtatctca ggtatggaca gtccaaagaa gcgcccgatc gtatacgcaa tcaaagcatt
     2401 cgttacatta taacttccag gcagcgggat cgtaaatgtt tctccttcta ctacaaaatc
     2461 ggtttgtgct tttccttttg ctgtcacttc cgcatgaaca tcgccatttc caataccgaa
     2521 tgttgtgact gtttgtacta atgttgccgt taaaggtgtc agcaacggtt catctgcggg
     2581 cacaacgagt aatccgtctg atacaagtcc gtcagtgatt tccattttgg ctttagcgat
     2641 tccttctcgc gacccaagat tttctatgtg tgcttcaccg atcattgtga ttgctgcagc
     2701 ttttggttga gccataagtg aaagttccgt gatttcattg gcgtgatcca tgcccatttc
     2761 caaaacgatc ttttctgtat cttggggcat gtgcaaaatc gtgtaaggaa gaccaatatt
     2821 attgttgtaa tttccttgcg tcttatatgt tttgtatttt tcagacaaga cagacgcggt
     2881 tagatctttc gtggtggttt taccattgct tcctgtaatt gcaacgactt ctgcgcctac
     2941 tttttccaag taataggttg ccaattgctg catggctttc aaaggatctg ctacaggaat
     3001 aactggaaaa ttttttggag cttgttcaac aggcaagctc caaaatgaag cagatgctcc
     3061 gtttgtgatc gcttgctgga taaattcatg tccatctcgc gtaccagcaa gaggaacgaa
     3121 taaacttcct tcggttatct tccggctgtc aaattcgaca ttggtaatct ttgtcagtgc
     3181 agagcattcg ctgcccacgg cttgtgcaat ttcttgtatt gttagattca ttgagatctc
     3241 tcctaaaaaa ggttgtgaaa aaagcgtttg gcctaaacgg cgggttcgca tgactctcac
     3301 ttccaagtaa atttctctat tcgtatttag aagctagaat gaacgcggtt acgcaatcac
     3361 tccagcctct tctttatttc tctttattca tttttttcaa aaaaagattg acgctgatgg
     3421 tatcgattca ttcctaactg gatcagttct tcaatcaaat caccgtattt caagcccata
     3481 ttttcccata agagtgggta catactgaac tccgtaaatc ctggcataga gtttaattca
     3541 ttcaggaata attcattttt atttgtcaaa aagaaatcgc accggctcaa tccgcttcca
     3601 cctaacatcg tgtaagctaa cttcgcgtac tcttgcgctt tttgataaac ttcttctggc
     3661 acttcggctg gaatctgcat ttcgatttta ttattgatat attttgcttc ataatcatag
     3721 aatgctacgt cttttacgac ttcaccaggc aaagtcgtcc gaacgtcttc atttcctaat
     3781 acagcaactt cgatttcgcg cgcttcaatt ccttgttcaa cgattgctcg agaatcatac
     3841 tgataggctg ttgctaaagc attttgcagc tcttctcggt tttctgcttt tgtaatgccg
     3901 acactagaac ccatattcgc cggtttgaca aacatcggat aaagcaaaga accttcacat
     3961 tgatcaaata cttttttagg attttctttc cattgattct taagtactgg tacataagga
     4021 acttgcggca caccagcagc ttgtaaaata tacttggtca tgattttatc catggcacat
     4081 gcactggtca atacgcctgc gccgacataa ggcatattca atgtctctaa gaagccttgg
     4141 atcgttccat cttccccgtt tggcccatgt aaaactggaa aaacgatggc tccttcttct
     4201 ttgatttcgc ccggattgat cacttttcct gtaaagcctt cctctgtctg tccacttggg
     4261 tcccatgaaa gatgcaagac atctttgctg gcaggttttt ctgttagtaa tggacctttg
     4321 acccattgtc cttcttttgt aataaatacg agttgaactt ggtaataatt ataataaatg
     4381 gcatttaaaa ctgaaaatgc ggaaagaatg gacacttcat gctctgcgct gcgtccgcca
     4441 tatagtaaag taatcttcaa aagattgtcc tcctgtattc taaatcgttc agtgatttac
     4501 tctcatattt tagcacaaaa caaaaataaa cgaataactt atttataaaa aaacgagcca
     4561 gcttctaaaa gaacgagcgt catttatttt ttgtcagcta gattatttgt cccgtttttt
     4621 ataaaaagtt atgataaaga aaaggaggga tgatgatggc gcaaacaaat ccacgcagcc
     4681 gcttggcaga aatcattcga gtgttcatca attacaatgt agtgccaaac tttgtacagc
     4741 aaaaaaatcc cgaacaggta aaaaaagcct ttgaagaact aggccccacc ttcatcaaga
     4801 taggacagat gctttctgtt cgagaagatt tgctttcttc tgccttcact caaacattca
     4861 aaacattaca agatagtgta cctagcgaca cattttcaac ggtcaaaaag acgatcgaaa
     4921 cagaactttc tctttcatta tcagatatat tcgatgattt ttcaaaatcg ccttttgcct
     4981 ctgcttctat ggggcaggct catcgtgcca agctgaagaa cggtgacgcg gtagtcgtta
     5041 agatccaaca ccctaacatc gccgaagaga tccgacttga tcttcaacta tttgaacgag
     5101 cgatcccttt gatcaaatac attcctgaaa ctagcgtagt tgatctaaaa ggggtactcc
     5161 aagaagtaaa acgttccttg atcaatgaaa tggacttctt aaaagaaagt caaaatggcg
     5221 aacaattcta tcaaaagaac aatggctgga aagagatccg cagccccaag atttatgacg
     5281 ctttttgttc gaaaaaagtg atcgtgatgg aagaaatgtc tggtaaaaac ttgaatcatt
     5341 taatgaacgc cgaaaacaaa actgaaactt ttatcactgg aattcaaaac aagcagctga
     5401 aacaagaagt tgcaaagctt ttagttgaga actttatgaa acaggtgttt gatgatggtt
     5461 ttttccatgc tgatcctcat ccagggaatc tgctattcca tgtactaaca aaagaagaac
     5521 agacacaagc tagccgaaaa actgaaacag tccatgaaaa agagttcggt tcctttgctt
     5581 ttcgagcctc cacttctgca gaagaccctg ttgcgccata taccatcaac tacatcgatt
     5641 ttggtatgat ggggcatctt tctgcaggac ttaggcaaaa actcacacaa gccgttttag
     5701 cgctgtatac gaaagatgct tatcgaatcg aaaaagcggt ccttcgactt tgtcagcaag
     5761 aaggctcgtt tgatgaaagt cggttccacc aagaactgac aagttttctt gaacagtatt
     5821 atgattctcc tattgatgaa atcaacttgc aagaagtatt cacacatgtc gtgacgattt
     5881 gtcatcaaaa taatctgcag ttcgatcgtg atatcacgct tttgctgaaa gcatttggga
     5941 cattagaagg ggtgatccgc gtcctcgatc ctgaagtttc cctcatggaa gtcgcttcgc
     6001 cttttgctca acattatttt ctcactcatc tggatgtaga agatacattg aaacaaagcg
     6061 gattagactt attggaaggg atgaaggctg cgcctaagat ccctcaacag ctccaccatc
     6121 tattagaaat gtggacttcg ggacaaggaa aagtcaattt ggaattgaaa aagcaagaca
     6181 aattattgag caggatcgaa agtatgatca atcggcttgt tttcggtatg attttagctg
     6241 cattgatcgt agggtcctcc ctgcttgtcc aagcagcacc tgtagaaaac gcagaggtcg
     6301 tttccttatt agggatattt acgtatgcta ttgccgcatt cgtcattatt tttttggcaa
     6361 tcgatgcatt gatccaaatg tataagaaga ggaaaaagta gaaaaaggtt gtgacagaaa
     6421 gaatcagctt caagaaataa gaaggggttt tacataaatt gtttctcaaa tttttgtgaa
     6481 aattcggctt atttttcgaa gaggctactt ctgaaacacc gagaataaaa aatgtgaaaa
     6541 agctgttctg cacccagtaa taagaacaat caaaaaggga acatggaaca catttatcct
     6601 gtttccctgt tccctttttg atgtattcga gcataaataa aataccttcg ttacctacta
     6661 tcttctgtac ttggtaaacc ttagtcaatt gcctttttta acgcttgacg aaaagacata
     6721 tgatctttct ccgtaaaggg ttttggaccc tttgtcctta tgccagcttt tcttaacttt
     6781 ccactatgat aacgttgttc tagaagcgtg ccgatattcg cttcgtcaaa ttcttttcca
     6841 gagtgatgga acactcgcac acccttcggc aatacaagtg aagctaaacc ataatcttgc
     6901 gtgatcaaaa agtcattctt cttaaccata ccgacgattt tataatccgc actatcagct
     6961 ccgcggtcta cgtagacgat ttggacatga ttagcgtatt ctttggtcgt ataatggtcc
     7021 acactggtca cgataaccac gtcaagacca taggattctc ctaattttat gacatcttct
     7081 tttactggag aaccatctcc atcaatgaat agcctcattc tttttcgcct tcttccataa
     7141 atgataaaca gttactaatc cgctcagtaa aagaccaaca ttgatccatt ttgccaagat
     7201 aagcagttgt acactttcta tcggcactga ttcatggttc agcgtgatca ataatagatg
     7261 gattggctct cccatttctt ttgctaaaac aaacaaaagc gtcatcaata aaaactggtg
     7321 gatcacactc cctttatttt gagtagtata cttgacaacg atccggcgat ccattggaat
     7381 agctgtatca gtttgataat attccttatt tagccagctg cctgttacta cgtgccagaa
     7441 actaagcaga aagacaccta tcgcaaaacc atttggaatc aagaggacca ataaagaaga
     7501 actcagtcca agcaattgca tagccaatgg agaccatgtt aaacgtttca aaatccatgg
     7561 tccgactatt tttgctgcaa tcaagcctgc tgcataaggc aaatacataa aaatcgaaag
     7621 tttttctaat ccgtacagta tgccaacata aaaactgcta aataaaaaaa ggaaattccc
     7681 tagcattcca tttagaaaag taaacagatt tagccagctt ggcaacttcc attccttctt
     7741 ctggtgtcct aaaacaaaca cgaacaagat gaacagcagc aagaaaccat aaatagcaag
     7801 atcaaaaagc ctttcatcga ataacaatcg ggcatttctc aaaagaaaca ataagccaaa
     7861 gaatatcaaa aataaaacaa gctctcgcgt agctaccaga tttcttttga tgtctttgaa
     7921 atccagttcg taacgcggat aatgactaac cgtatggtag gccatgacgt aaaaaagtgt
     7981 ataaatagta aagcttgctg caatctgagt cggtgcaggc aactcaatcg cttgatacag
     8041 gagaaatagc cagatagctg caaataagta ctttttccca tccatattga taaaaccttg
     8101 cgtcttttcg tgaaaattga ccgtggtatt agcaggtaca agccatgctg cactcagccc
     8161 tagcaaaaca cttgaaaaat aaaataaagg aaaataaaat acgcctaata ttccaagcaa
     8221 tgaaccagca ccaccaatca gcagagcgat catcagcaac gtgtaactat ctagaccaaa
     8281 tcgtagactg ttgactaaaa atagtccagt catccgaaag gcataaaaca gcgtaaatgg
     8341 caaaatcgtc agccaattat gcgagtctgt tagtcccaaa aataaaagat aaggaataaa
     8401 aataaccgtg ttacttaaga taaagggcgt tgtttgtgta aaattacgcc caaatcgttt
     8461 gagtttttcg aacatgacaa tggctcctta aacagtctta taactaatct gctcttcgat
     8521 tttagcatta aaggggaaat aaaccaattt tacagaatat attcttgtaa aaaaaaatac
     8581 agaaagaagc ataagcttct ttctgcattt ttacggtact tgattactca agcagacaag
     8641 cccttctcca caaaagtctt gcccgacacc cctgcatccg gcaggtgata aagatagaaa
     8701 tcaattatcc tgtgcctcca aaatcaatta ggagctctgt aaaccagagt ccttctcgac
     8761 ccgtcgcata aatttacttt aacacagttc ctatgtttat gcgagagctt ttttcatttt
     8821 ataatcgacc atttgaaatc cttgaccgat atctgaaata agttcttctg taatctcaaa
     8881 tccttcatgc ttataaacct cgattgcttg atgattcccc tgattcactc gcaaaaagat
     8941 ctctctttcc tttgtttgcg cagcaagttc ttcataccag cgaaaaactg aagaagtcaa
     9001 tccttgacca cgtactttat ttagcaaata taatttactt aaataaattt ttccatttat
     9061 ctcttcataa gcagtgtaac cgacagtctt ttcttcgctt tttaataaaa agtaggacac
     9121 accttctgtc agttcttttt gaatctgttt ttttgactga taagttttca gcatgtaatc
     9181 cacttgtttt tgaccaatga tcggcacaaa aacttccggc catacttctt gtatgactgc
     9241 catcagctca tccagttcat tttctgttac ttttattttt tccatacacc cacgtccttt
     9301 tttacattat aaatgacctt gcgcttgatg gaataaaaag agcatgatca tgctatacac
     9361 acccaccgac cacggtttca agaaaatcac aatctgcata aattccctaa aagataattt
     9421 cgtcaaacca gctactagac agatcaagtc gtctggcgca aagggaagca gcaaggtaac
     9481 aactagtact tttttaatat ctttcgtttt tcttgtcagc aattcatcaa atttctgata
     9541 cttttttggc gataaaataa gctggacaaa ggctacgcca tagtaacgga caagcaaaaa
     9601 tccgattgct tccccaatca ctaggccaat acaactatat aaaagcccaa atccattgcc
     9661 aaacatcagc atgcccgcta ctgaggagat ccctcccggc aaaataggaa tgatcacttg
     9721 gatcacttgc aacagaacaa atatcatcac tgcatacttg ccaaattgct ggataaacgc
     9781 ttgcaaagac gtgctcgatc gaaaaatccc atgatgataa gcataaagaa tcaacacaaa
     9841 gaaaaaaaac agaccaataa tgggcatgat ctgaagacat ttttgtaaaa ctgatccttt
     9901 tttagacatc tatattcccc acatcttttt tcatttatta aaactgcctc
//
LOCUS       DAZKCH010000090         9818 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000090 DAZKCH010000000
VERSION     DAZKCH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.091"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(34..2154)
                     /locus_tag="ACG84X_002378"
     CDS             complement(34..2154)
                     /locus_tag="ACG84X_002378"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFP9128207.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2384..3562
                     /locus_tag="ACG84X_002379"
     CDS             2384..3562
                     /locus_tag="ACG84X_002379"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFP9128208.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3578..4336
                     /gene="aroD"
                     /locus_tag="ACG84X_002380"
     CDS             3578..4336
                     /gene="aroD"
                     /locus_tag="ACG84X_002380"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFP9128209.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFFSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4359..4844
                     /gene="ybaK"
                     /locus_tag="ACG84X_002381"
     CDS             4359..4844
                     /gene="ybaK"
                     /locus_tag="ACG84X_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFP9128210.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4915..6168)
                     /locus_tag="ACG84X_002382"
     CDS             complement(4915..6168)
                     /locus_tag="ACG84X_002382"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFP9128211.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6285..7634
                     /gene="gdhA"
                     /locus_tag="ACG84X_002383"
     CDS             6285..7634
                     /gene="gdhA"
                     /locus_tag="ACG84X_002383"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFP9128212.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7746..9092
                     /locus_tag="ACG84X_002384"
     CDS             7746..9092
                     /locus_tag="ACG84X_002384"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFP9128213.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9400..9786)
                     /locus_tag="ACG84X_002385"
     CDS             complement(9400..9786)
                     /locus_tag="ACG84X_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFP9128214.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3130 a         1785 c         2009 g         2894 t
ORIGIN      
        1 aattttgtcg ctgctccttt taaatttatt ttatcattcg gaagaacttg tggtcgttcc
       61 gtgaagttct tggtacgttt gcgttttata aagatcaaca gttgattgtc cgttgtgttc
      121 actaaagaca ctagttgact tgtcaccaag agatttttca gcttctttta atttctctaa
      181 gccattcttg tagtcataat cactggtatc aattgggtct aatccactat tcgtatagaa
      241 ccgaagaaga tcaccattat tgatttggtc agaaacagct aactgtttat caactttttc
      301 tttcagtgaa tcaatttcat tctgtacttc ctcagtaggt tcagtaatag cttcaccagt
      361 ttcgttacta tagatcgtac caccgtagta agtatatttt ggtgtaacaa aatcaccatc
      421 acggaaagaa acaagctgtt catgatcttt cgagaataga tcttgtccta actgaatata
      481 attttttgta tctacaccta gtaagtgaag taatgtaggc aaggcatcaa cttgtccgcc
      541 gtaagtgtga ttgattccgc cctgtgtttg tccagggata tggatcatat aagggacacg
      601 ctgcatttgt gcattgtcgt agtttgtcca agtagaactt gtttttccaa ctaattcagc
      661 tagattttta tttcttgaat tcgagacacc gtaatggtca ccgtaaagga cgatgactga
      721 attatcatac aagccgcttt ctttcaaata attgaagaat tcttgtacgg cggtatctaa
      781 ataattggct gtcgcaaagt aaccgttgat cgtttcatca tttgtattgg ctaacgggaa
      841 tcctgcttcg tcattggtga attttgaata aggataatgg ttagatacag caatgaattt
      901 tgaataaaat ggttgttgca gacgttccaa gtattgtacg gattgttgga aaaatggttt
      961 atcatgcaac ccgtattgga acgaattgtc atcattaaca tcataataag aagaatcaaa
     1021 gaaataatca tatcctaaat tcttgtatgt ctcgtttcga ttccagaatg taccagcgtt
     1081 cccatggaat accgcactaa tgtaaccttg tgtttgactt aaaatatcag gtgcagcttg
     1141 gaaagtattt tttccgccta attgtgtgaa caaggagcct tgattcaagc caaacaatga
     1201 attttccatc agcgtttccg catcgcttgt ttttcctgct tttacttgat ggaaaaagtt
     1261 gtcaaaactg aacgtgctgt tgctgtggta aagactattg atgaaaggtg taacttcatg
     1321 ctggagacca ttctcatctg tcaatttata atcgatcagg aattgctgga agctttctaa
     1381 atggatataa atcacatttt ttcctctagc gagcccgaac aaatcgtcat ttggtgctgc
     1441 ataatgttct tttacataat tttctacttc tttcatatca ttgggacttg cttctgcccg
     1501 cacttggttt gtctggtaag tttgaacacc gtcataaacc atgaaagcat tcaagccaag
     1561 atatttgacc aaataatcac gagagaatgt tcgagtcagc aattctggac gatcagcttc
     1621 cgccataaaa agatttcctg agaaaatcat aactgctaat gtagagatcg caaaagccat
     1681 tcttgctcgg atcgggcgag ggtccaactt gatttttttt gcaatcagca gaacagtcaa
     1741 gataataaaa tcgatccaat agatcacatc atatgggcga aacagtcgaa tggcactttc
     1801 tcccagacca ctcgctactt tcccagcacc taaaatcgtg ttgatcgtaa tgaagtccgt
     1861 gaattctcga taataagtga cattcgaaaa aacaagcaat gtcaaaagaa aataaatgac
     1921 catcatcgtg atataagcaa ctctagggcg tctgatataa agagcaattc caagtaataa
     1981 caatgtagtt gcaatagggt tgataaacaa gataaagtat tgaatgccac tttcgattcc
     2041 gagatggaaa tcaactaaat aggcaaaaat cgttttcaac caaagtaaaa cgactagtaa
     2101 agaaaaaaat ccgagcctct tattcaaaaa ggcaggtgtt tttatacatt tcaagataat
     2161 cttcctttct gcacttctta atcacagaag tgtcctgaaa ccatgttaca cagctcactt
     2221 attctcattt attttactag tatgacaata tagtgtcaat tgaaaccaga agtttatgct
     2281 gtttcattaa ggttttcttt aagcttcatg aaaaaatgag cagtaagaca agtcctatgt
     2341 tttttgttat acttgggaag agaaagctaa agcaggtgaa ggaatgaaag taaaagtaaa
     2401 aaaaagagca agcaatcgat tgaaaaaagg atatccactg atccaaaaag aagaccttgc
     2461 tcatccccaa aaagaaacca cgcaatgggt ggaattagtt gattcgcaaa accaatttat
     2521 cgcaaaagga tatctaggaa agcagaataa gggaatcggt tgggtattga gccagcagaa
     2581 catcccattt gatcaatctt tttttgaaga attttttgtg aagtcaaaag aaaaaagaac
     2641 tttctttttt tcagatgatt ctactaccgc ttttcgtata ttcaatggag aaggagacgg
     2701 gatcggcggt ctgattgttg attattatgc aggttatgct gttttttctt ggtataacga
     2761 aacgttatat gcacatcgtg aattattgat tcaagctttt cgtgaaatct acccggaaat
     2821 cataggaggc tatgagaaaa ttcgatttga atcagtaaat ctgcctgaga gccagttcat
     2881 ttacggaaaa gaggcaccgg aacccttgat cgtaaaagaa aacggagtaa aatttgccgt
     2941 ttatttaaat gaaggattaa tgactgggat ctttttagac caaaaagaag tacggggatc
     3001 attagcagaa ggtttcgctt ctgggaaaac agttttgaac atgtttagtt ataccggcgc
     3061 cttttctgtt gctgccgcaa tgggaggggc aatcgaaaca acaagtgtcg atctagcaaa
     3121 acgcagttta aaaaaaacac aggaacagtt tgaagtgaat ggtttggatg tcgatcagca
     3181 aaaaatcatt gttatggacg tattcgagta tttcaaatac gccaaaagaa aacaattttt
     3241 atatgacatg attgtattgg atccaccaag ttttgccaga aataagaaaa aagtctttcg
     3301 cgtagcaaaa gattatgggg aactggtcaa ggatagtctg gatattttag cagaagacgg
     3361 gatacttatt gcgtctacaa atgctgcgaa tgtctcgata gaacaattcc aaacaatgat
     3421 tgaagaggaa ttccatgcca aaaatgtttc ttttgaacaa cttgctttat atcgtctgcc
     3481 aaaagatttc cagacgacgg ataccttttt agaaggcaat tatctgaaag tgtttgttta
     3541 tcaaattaaa aataaccatt agaaggagcg atgcagaatg gttcgggtaa agggattgaa
     3601 tataggaagc ggtagaccaa agatttgtgc gcctcttatc ggggccgtcc gagaggaagt
     3661 attacgtgaa gcagttcttg cacgtgaagc aggggccgat ttagtcgaat ggcgagtcga
     3721 tcattatcgt gaagtttttt cttttgatga agtagcagaa acattggttc ttatccatga
     3781 gatgcttgat ggactgccgt tattatttac gtttcgtacc ttagctgaag gcggagaaca
     3841 agacatatcg atccgtcagt atcgcgacct ttatgaacat gtgatacaca caggattagt
     3901 agatatggtc gatatcgagt tgttcaaagt agaaagtcta ggaaaaagac tgatagagga
     3961 aatcaagtct ttaaacattc ctttaattat cagtagtcat gattttaaag aaacaccagc
     4021 agaccctgtc ttgctttacc gattgaatgt tatggaacat tttggagccg atatcggaaa
     4081 actggcagta actcccaata atgaacgaga tgttttgcgg ttgatggagt tgactagacg
     4141 ggcaaatgct tttttctcca tgcctattat tacgatgtcc atgggaaatc ttggtaaaat
     4201 ttctcgtctg gttggcggaa cgacgggttc cgttatgaca tttggttcct taagcagcga
     4261 ttctacttct gctccaggac aattaccggt caaagcattg aagcaaatta ttcaattatt
     4321 aaatgaaccg ttgtagaaca agtttgaggt gatatttttt ggcaaagaaa aaaatagtaa
     4381 aaacgaatgc aatccgtatg gtcgaacaaa aaaagattcc ctatacagag cacgaatatg
     4441 agtgggacga aagccaccta agtgcgtcat cggtcgctga acagcttcca gaaagccaat
     4501 ctcgtatatt taaaacactg gttgctgtgg gcaatgtgac ggggcctctt gttgctgtga
     4561 taccgggaga agccgaattg aatctaaaaa aattagcaaa agtttcaggg aataaaaaag
     4621 tagaaatgct ccatttaaaa gatttggaag caacgaccgg atacatacgt ggtggctgct
     4681 cgcctatagg tatgaaaaaa ctatttccta cttatttaga tcaaattgca gaaagctatg
     4741 aacaaatcat tgtctcggct ggcagaagag ggctacagat ggagttagca cctcaagata
     4801 tctgtgcatt aacgagcgga caatttgcag atataaaaca ataaatcata cgtataaaag
     4861 aaagaaggag gccgggatgt tgtttgtcca gtctccttct ttctttttta tacattatgc
     4921 tctttgcccg gcattcattc ctgctacatg ccctgtagcg aaagccgctg tgatattaaa
     4981 gccgccagta taaccattga catccagtaa ttctcccgca aaatacagac catcaatgat
     5041 tttactctcc aatgttttag gataaatttc ctttagagaa acccctccgc cagttacaaa
     5101 tgatttctca ataggaaaag ttttgttgat tgatagctta aactctttgc atagttgaac
     5161 aaaatcttga atttgttttt gagaggcttg ttgtcctgtc agatgatcca tttcaagccg
     5221 ctcaagaaag aaaactaaca atcgctcagg caatatacca tgccaagcat tgaccaagtt
     5281 ctttttggtt gctttacttt tttctgtcaa tatatgaata agctcttgtt tggtttgtgt
     5341 agggaaacaa tccagagaaa gtgtcactgg ttctcccgtt ttctctaatt ctttattgac
     5401 aaaacttgaa caacgcagtg cagccggacc agaaataccg aaatgggtga aaagtaaatc
     5461 catcgtatgt tcagtcaata cacgaccttt tttatttaaa acgcgtaaag tgatgtcttg
     5521 taaagaaagc ccttgaagtg ttttctcctg aatatacggt tcatccgata tcaaggggga
     5581 ctctgtcgca taaagaggcg tcaccgtgtg acccactcgc ttcacgatct tgtacccatc
     5641 tccagtagaa ccagtagatg gataagtccg tccaccagtt gttaagataa tggcaggagc
     5701 atggaactct tcgaattccg tgcgtatacc gtaaatttta tgttctttgt ggatcaattt
     5761 ctctactcga gtagagaata gaagcgtcac atctagttct ttcagacgat tgagcaatgc
     5821 ttcgataatc gtttttgatt tatttgttac aggaaacatc cgtccatgat cctcttcttt
     5881 taaatgtacg ccttgtgatt caaagaagtt catgatatcg aaattattcc attgcgcaaa
     5941 cgtactatat aaaaactttc catttccagg aatatgtgca atcaaatcat caacaggacg
     6001 attgttcgta acattgcacc gaccaccacc tgtcatcagt agtttttttc ctgctttttt
     6061 gtttttttcg atcaagagta cgcgtgcgcc ttgttcagct gcactgatcg ctgccatcat
     6121 cccgcttgtt ccagcgccga ctacgatcac atcatacagt ttttccattc cctcacctca
     6181 aggaaagtgt agcatatctg aagaaagaaa acagaaaaaa atgttttgag ccaaaagaga
     6241 aaatgagcta aaatgaggga agataagcaa aggagcgtgg aacgatgaca aacgcaacag
     6301 aatatgttca agcaattcaa gaaaagctac atcaaaagga tcaagggcaa gaagaatttt
     6361 tacaagcaat cgatgaattc atgcccacgg ttatgtcttt tttggacact catcccgaat
     6421 atatcgaaaa gaatatctta gaacttttaa cggaaccaga aagagttatt caatttcgag
     6481 tgccttggca agatgatgaa ggaaactggc gagtaaatag agggtaccgt atccaataca
     6541 actcagctat cggcccttat aaaggtggat tgcgcttcca tcctagtgtc aatctaagta
     6601 tcttgaaatt tttggctttt gaacagattt tcaagaatag tttaaccggt ctgccaatcg
     6661 gtggaggaaa aggcggaagt gacttcgatc ctaaaggaaa atctgataat gagatcatgc
     6721 gtttttgtca aagtttcatg ctggaattgt caaaacatat cggcccatcg attgatgttc
     6781 ctgcgggaga tatcggtgta ggagctagag aaatcggcta tttgttcggc gaatataaac
     6841 gattgaaaaa atatgatact ggtgtgttga caggtaaacc tttggatttt tggggaagta
     6901 agatacgtac ggaagctact ggttatggat tagtgtatta tgtcaaacat ctattgaacg
     6961 aagaaaaaga ttcatttaat caaaaaacag tttttgtttc cggaagcggg aatgtagcca
     7021 tttatgcaat cgaaaaagtg caagagctag gcgggaaagt tgttacatgt tcagattcta
     7081 gcgggtacat ctatgatcca gaaggaatag atgtgaaact attgaaagaa gtcaaagaaa
     7141 tcaatagaca acgtttgacg gaatacgcaa accaacgtcc ttctgctatt tatcatgctg
     7201 gagaatctgt ttggacattg aaagaaaaag cggatatcgc tttgccatgt gctactcaaa
     7261 atgaaataga cgaaagcttg gccgaaatct tagtagaaaa tgggatcaaa atcgtagcag
     7321 aaggcgctaa tatgccatgt acagtaaaag ctgtttctgt tcttcatgaa gcaggcgtgt
     7381 ggtattgtcc aggaaaagct gctaatgctg gaggagtagc agtatctgct ttagaaatga
     7441 gtcagaacgt ccagcgattg acttgggaaa gagagcaagt ggatgagcag ctggatcaaa
     7501 tcatggaaac gatttaccat acgtgtcgcc aaacagcagc cgagtacggc gacgaaaaaa
     7561 atctgcttct tggagcaaat gttgctggat ttgaaaaagt tgccaaagca atggcagcag
     7621 aaggtttagt ttgaaaaatg aaactttctt ggaaatattg tcagcatttt gtttatttgc
     7681 ttgaaaaata ataaaaaaaa acgtaaagta ttacctgtag agtaaaccta taaggaggag
     7741 aacaaatggc acacattcat tttgactatt caaaagtagc accgtttgtc aacgaacaag
     7801 agttagggta catgcaaagc caagtaacag cagcccacaa cgaattacgg gaaggtactg
     7861 gcgcaggaag cgacttccgc ggctggatcg atttaccaac gaactatgac aaagaagaat
     7921 ttgcacgtat caaagaagca gctaaaaaaa tccaatctga ttctgaagta ttagttgtta
     7981 tcggtatcgg tggttcttat ttaggcgctc gtgcagcgat cgacttcttg aatcacacat
     8041 tcttcaattt attagatagc aacacaagaa aagcaccaca aatcttcttt gccggaaatt
     8101 caatcagctc aacatatatt gctgacttga tcgaagtaat cggtgatcgc gacttttcag
     8161 taaacgttat ttcaaaatct ggaacaacta ctgaaccagc gattgcgttc cgtgtattca
     8221 aagagcttct tgttaagaaa tatggacaag aagaagcaaa caaacgtatc tacgctacaa
     8281 cagataaagc aaaaggtgca gttaaagtag aagcagatgc agaaggttgg gaaactttcg
     8341 tgattcctga tgacatcggc ggacgtttct ctgtattaac tgctgttggt ttgttaccaa
     8401 tcgctgttag tggtgcagat atcgatgcat tgatgcaagg tgccgctgat gcaagcaaag
     8461 catactcaag cgacaaacta gaagaaaacg aagcttacca atacgcagca atgcgcaaca
     8521 ttctttaccg taaaggcaaa gtaactgagt tgttgatcaa ctatgaacca ggaatgcaat
     8581 acttctcaga atggtggaaa caattgtatg gtgaatctga aggaaaagac caaaaaggca
     8641 tctatccttc aagcgcaaac ttctcaactg atttgcactc tttaggacaa ttcatccaag
     8701 aaggacgtcg caatattttt gaaacagttg tgaaggttga aaaacctcgt aaatcaatca
     8761 caattcctga acaagcagaa gatttagacg gtctaggcta cttgcaagga aaagaagtgg
     8821 acttcgtaaa tacaaaagca tttgaaggaa cattgcttgc tcatacagac ggtgacgtgc
     8881 ctaacttgct agtcaaaatt ccagaaatgg atgcttatac attgggttat acaatgtact
     8941 tctttgaaat tgctgtaggt atttcaggtt acttgaatgg aatcaaccca ttcgaccaac
     9001 caggtgtaga agcttacaag aaaaacatgt tcgcacttct aggcaaacca ggctttgaag
     9061 atcttgctaa agaattgaac gaacgcctgt aagataaggg tttttcgcta gatttaaata
     9121 atcagtgata gaaacatgtt cgctttaaaa tgaaaactgg tacccattta ggtactcaaa
     9181 catactgcat cgtttattca gaataagggg ctgtgacaag acgtttgtca cagtcccttg
     9241 tttgtataga aatcgattga ttgccttgct ctttagtttg ttttaggact ttaagaacag
     9301 tgaggctgac ttcgaaggtt aattctgttt ttttgttttc tagaatcagt aagcaaaaaa
     9361 gcactcactt cgagtgcttt tttgcgatat attcttagct taagataggc ctaatttttc
     9421 ttttacagat gagggtacct tatcgctggt aattactttt ttctctatga tccgcttttc
     9481 gcttgctttc aactgcaaga tcgttccttc ggggtaagca gaaccattgg cagagtcacc
     9541 agaagtaatg acatcgaaat ctaactgtct tttttcaccg ttttcagcat aagcatctac
     9601 gttgtattta aaacctcttc caattacttc cccattatct gctttgatat cagtttctgc
     9661 aggcattgga gctttgacta ccgcataata atctttacct acataagtag actgatagta
     9721 gtcccaacct ttccatccta taaaagcaat caatatgata acgatcaacc ctaaaatttt
     9781 tttcatgaaa gatctccttt tttattttta ttataccc
//
LOCUS       DAZKCH010000091         9593 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000091 DAZKCH010000000
VERSION     DAZKCH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.092"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..641)
                     /locus_tag="ACG84X_002386"
     CDS             complement(<1..641)
                     /locus_tag="ACG84X_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFP9128215.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQT"
     gene            complement(643..1407)
                     /locus_tag="ACG84X_002387"
     CDS             complement(643..1407)
                     /locus_tag="ACG84X_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFP9128216.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1415..2092)
                     /locus_tag="ACG84X_002388"
     CDS             complement(1415..2092)
                     /locus_tag="ACG84X_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFP9128217.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(2129..3514)
                     /locus_tag="ACG84X_002389"
     CDS             complement(2129..3514)
                     /locus_tag="ACG84X_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFP9128218.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3724..3808)
                     /gene="ffs"
                     /locus_tag="ACG84X_002390"
     ncRNA           complement(3724..3808)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACG84X_002390"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3831..4346)
                     /gene="tadA"
                     /locus_tag="ACG84X_002391"
     CDS             complement(3831..4346)
                     /gene="tadA"
                     /locus_tag="ACG84X_002391"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFP9128219.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4453..5310
                     /locus_tag="ACG84X_002392"
     CDS             4453..5310
                     /locus_tag="ACG84X_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128220.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5391..5726)
                     /locus_tag="ACG84X_002393"
     CDS             complement(5391..5726)
                     /locus_tag="ACG84X_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128221.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5793..7163)
                     /locus_tag="ACG84X_002394"
     CDS             complement(5793..7163)
                     /locus_tag="ACG84X_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFP9128222.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7241..7777)
                     /locus_tag="ACG84X_002395"
     CDS             complement(7241..7777)
                     /locus_tag="ACG84X_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9128223.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            8086..9567
                     /locus_tag="ACG84X_002396"
     CDS             8086..9567
                     /locus_tag="ACG84X_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128224.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         2908 a         1969 c         1502 g         3214 t
ORIGIN      
        1 tttgtttgtt tcaagctatt ttttcctaag aaaagaaaaa cagcaaaaaa taattctaat
       61 aatacaaaaa ataagataaa gctatgcatg aaaaattctt ctggaagtac attgatgatt
      121 ggatcagtaa cgggatcgaa taaccagtca tcgttgttga aaaacgtttc atgaaaaagg
      181 ataaaaaagc gatcaaatcc tatcatcatg aaaaaaccga aaacaactgg cagtaacatg
      241 ccgatttgaa acggacgaat caaccgccaa agccgatcat tcttttgcaa atatttgata
      301 aacaaaatac tcgggatcaa agtgatgaaa aacacagcat aatccactaa aaacaaaatt
      361 ttcacttcat aaaagtgatg ggctccgcta gcagaaactg ggaaatctgg caagctgagg
      421 atggttttga agggattatt gagataattc attaggtgat caaaattttt cagtaacgtc
      481 tcttgatcta aagaagtata atccaaaatt tgcaaatgtc cgatatcaaa tacgtatagt
      541 ggtcgaaagt tgatcgtcac accaactgcc agactgatca gtgtcagaaa taggctgaac
      601 aatccagcat attccatcca ctgccatctc gaatttttca tattagaagc tccattcatc
      661 cagtgattgt ttcacatagg tagctgggat aggcaaccca ggtacatctt cttcttttgt
      721 aaaacctgat aaaacgagca aagtatctat attattgcgt atcccagctt ggatatctgt
      781 ttcatagtta tctccaacca tgattacttc ttctttttgc agccctaata cttcaacggc
      841 tttatccata atgatggctt ctggttttcc gatgtagatc ggcggcgttt gggttgctgt
      901 ctctacaaaa gagatgactg accctgctcc aggaagaagg ccgcgttcag taggtatatt
      961 cttatctggg ttcgttccaa tgaaagtagc acctttttga atagcaagtg ttgctttaac
     1021 tactttttca taggtcagat aattatctaa gcctaccact acatagtcag gagcctcttc
     1081 ttcccatgta aatccggcag ctaaaatcaa gtcaatcaat cctgcttctc cgataacata
     1141 gacttttttc ccttttccat ctgctttcat aaaatcgatt gttgccaaag tagctgtgta
     1201 gactgtctct ggagctacat gaatgtcaaa ctcatctgct agacgattag ctactgtttc
     1261 tggtgactta gtcgtgttat tggtaacaaa caagaaaggt aattttcttt tttgcaattc
     1321 ttccacaaat cgtttaccgg ccggtatggg ttgtgtccca cgataaatcg ttccgtctaa
     1381 atcaattaaa tatcctttat agtccattca tccactactc ttcccttttt ctgatcgtaa
     1441 atgctgtttt tgttttttct acttgtttag gttgttcttg tttttttact ttttcagagg
     1501 tttttgctga ctctgttttt cgatttttaa taaccggttt tttgcgatta gatgcgactg
     1561 gtcctttttt ctcatcgata tacgcacgat tatggttttt tttctttttt cggcgctgag
     1621 ttgtcttttc ttttttaccg ccgattctct cgatgacaaa atacgcacaa ccaaaattgc
     1681 aatattcgta aagatagtct tccaaggaat cgattcgctg atctggatgc gcccgtcgat
     1741 tatccgcttg gaaaaatcct tttaggcgta gttgttcata accccaatct cctacgatat
     1801 aatcatatcg ggctagtaca tcactgtaac gttctccaag cttttctgca ttaaatcctt
     1861 cacgataatc ggacacaagc cgataatgtc tttcacctat caaaaaatta ctgtcatcta
     1921 acagtgtcac tagctcgcct ttgacttttt ctgctttagg ctcctcaacg atttcttcca
     1981 aagcagctgt cagttcttcg gtgactgttg tttcctgttc agctgatgat tttttcttag
     2041 caatttctgt tttatgctca acgttctgct gttcattttg ttttgcagac atgcgttcac
     2101 cacctatctt ttttattata ccttgttttt atttgattgg gtagtgagct ttcaagtaat
     2161 ctcctaccac acttcggata aattcaggga acaaaaattc attttttcca gcaatctcaa
     2221 tcgttggaaa aaatggaaca aacatcaaat gatctacggt agtaaaagta taatttttat
     2281 tcagatcgat tggcttgttc ttccaaaaga cttgatggtt aatagaatca tatgtgattc
     2341 cattatagac catctgccca aaaatcttac cgcgaaatcc cattcccttc ataggatagt
     2401 tacgtaaaaa gttacgattt ttttctattt ctaaaactaa gcggatcaga tcatttccac
     2461 ccaatgtgac atttaacaag tgcatcggat gcggcaacgc agtgtgaagc tgatcctgat
     2521 tgacccgccc ttttggaatt tcagttaaaa acagaccact gtttaatatt gctgcttccg
     2581 tctttcctcg ttctttcacc gcctcaaagg ctacttggat aaacgaatgc tcattgaaga
     2641 tatctagact cagagaaaat ggcaaatctg ctacttcttt ttcttttaat aattcatgcc
     2701 cacgttctag ataactattt atttcttgtt catcttctgt aaaagctgtc attgtttcgg
     2761 tagggatggc tttggctgaa tgcttaagga tttttttctc ttcatcgatg gttaaatgga
     2821 cttcaccgac atactgcccg tactttccag cggctgctat ttggacatca ttgattacgt
     2881 gaccttctct gaataaatga tgggtgtgcg atcctaaaat aacatcaatt gctggtattt
     2941 cttttgcaat ttggaaatca tcctgaatcc cgagatgact catcaaaact aaaacatcca
     3001 cttgtgaacg taaatcttcg actaattctg gcaaaatatc ataaggattc cgtatgtccc
     3061 agccattcgg attataagta agcggaaatg gagcagtaaa tgcaattagt ccgattttcg
     3121 tctggtgttt cgttgtaatg attttatatg gtttcgtcca tgccggtggc tggagcgtat
     3181 ttttatcgaa taagttatcc aggatgatat caaactcagc atgatcgtat aaatgattca
     3241 actcttcttt ggaatttcct acgccttcat tgtttcctat cgtcgctgca tcataaccaa
     3301 cttcattcat cagcaagata ttttcctgtc cattcgttgc ttctgacaat ggatgccaac
     3361 gatccacaaa atcacctaga tctactgcaa tcgttgtcgt tttttctttc ttttcgtttt
     3421 ctcgtttacg ttgatccaaa aaccttctga tccttggcca attttctaaa tgagaatgca
     3481 gatcattcgt atgtaaaatc actatttttt ccatgtaccc tctcgcctct ctttatcttt
     3541 atcataccat aggcagcttt ttcttccatt gaaacaagct ctatttcaga gtttttcctg
     3601 ccttgaagca aattgtataa gtacaatatt cgataaatca gtctggctaa aaaatcagga
     3661 acattcattt ttacagtact ataaaaataa aaaaaacaga cccgaaagtc tgttgtcgtt
     3721 tcattataat cagacacatg gcggaacctg cttagtgctg cttccttcca gacctgacac
     3781 gcttcacaag cccaccattg tcctagcctt tcggcaaaga atagtatacc ttatttttca
     3841 ttcgttgacc agtctttttt taatttcttt tttcgctggc ggagctttcg gaaaaagtca
     3901 gtcaaaatca tcccacattc gtcttctaaa atgccacctt ctacatatgc ttggtggtta
     3961 aaccgctcgt cctccaaaag attcatcaag gtaccggctg ttccgccttt tggatcatac
     4021 gcgccgaaat aaacttctgc tacacgagac aaaatcatcg cgccgctgca cataggacaa
     4081 ggctctaagg taacaaaaag tgcagcatct tccaagcgcc agcttcccac tttttcacag
     4141 gcttccttga ttgcaagcat ttctgcatgt gtagtagcat cttgcgtggt ttctctaagg
     4201 ttatatcctc ttccaatcac ttttccatcc aatacaacca ctgctccaat cggaacttca
     4261 tgaagcattt ctgctttctt tgcttctgcc aatgcaaggc gcatccattt ttctttttct
     4321 actgcatcaa gatttgtatt taccaattac ccttccctgc ctttgttttt tcttgtttta
     4381 ctttagcata tgataaaaag gctgtaacta actttttttt ctatggtaaa ataaatacaa
     4441 gaggtgaaca agatgaaaat ggataaatta cttgctcttt acccacaagc acagaaaaaa
     4501 aactctccag catcagaagc ggatatcctt tcttttgcaa ttgatgatgc ttttatctgg
     4561 atcaaacaag attcattatc tcaacaagaa accagccttt tgaaagcgtt attccctgta
     4621 atcaacgatc aaaaaaaaca cccatggtat cgctatcttt ttaaagatgc ttcttgtgtt
     4681 caagaaaaaa gctttcgttt gatccagctt cacgtcgaat caaaaggaga attcttaaaa
     4741 aaagaatggc aagatactat tttggaatta tttcgctatt ctgctgattt ctttttttat
     4801 acagacacag atgcgctctt agtcgaacaa ataaaccgtg attatcttga tgctactgaa
     4861 atcaacggta tttttctatc tttagatgct gattttgata cgacaacgtc tgtattcgtt
     4921 ggttctttcc attcacctgg caccgacctc gtccctttgt ttgctgaaga aagaaaaatt
     4981 tttttaacag agcaaaacaa tctttatact cacagccgta ctttttctat gcaagatgtg
     5041 gctttacatt actatacaaa agatactgta aaagatagta agttgatcaa aagttacata
     5101 gaactgatca aacaaaatga aatggaagtg atcattcaag aattatggaa tgaattaggc
     5161 aatgtcagct ctgctgcaaa aacactgttt cttcatcgta atactctaaa atatcgaatc
     5221 gaaaaatttc aagaacagtc tggtttcaat ctaaaaaaag ccaacgattt actgttttgc
     5281 tatcttttat tgcttcatga acataattaa agatagatta aaggggttgt gacaataatt
     5341 ttgtcacaac cccttatttc gaatgaatag tgttcaaaag ctagtttctc ttacatcatt
     5401 ttttcaacaa aatgcattag ccggtctttt acatcttcgg ttgaatcttt gattgaatca
     5461 ccataaacag agattttctt ttttcctgat ttgatttttg ctaacattcc catcaaagaa
     5521 tccaagtcac tatctgaaag accatctacg atttctagta atttttcatt tccatcaaat
     5581 ttgtcataga cgaatttttt tactttcgtc cgagtagtca tatgatggat cttttccatt
     5641 acttttcccg atacaacgac tgctgtcgct acactggcag cggctgctac gcttaatccg
     5701 attgttactt ttgttgatgt tttcataagt atcagctcct ttttatctat ctccatcata
     5761 gcatagacaa aaaaataaac gaactaatcc actcagtgaa atctcaatcc tttagggaaa
     5821 aagttcttta ctgttccttt tacttgtttc ccaaatccga caggtatctt atctaatact
     5881 agcaaaaccc atccttgatt cccatcacgt tgaaatgttt ctcctgctgt gtaagattgc
     5941 cattcctttt gagtgatcgg caagcaaggt atattctcta tcttttttgt agcaagcgct
     6001 aatgcatagc taggttcaaa tcgattcttt ttgaaatctc ctaaatgcaa acctgtacgt
     6061 acgactttta aaccatcgag agaaggggct aactcaggaa cttcccaaag atggtcgttg
     6121 aacactaaaa gtcttccagt agcttcataa tgaaaatcat ttgaaaactc cgtccagagt
     6181 ttttcctgct cttttgtcat ttgcacttta cttttttttc gtgtcttctt ttctttatgc
     6241 atctgatttt gtccatgaaa agtcagcttt gcaacaaaat gtccttcacc ctgatcttta
     6301 tgaggccata tacgtattgt tttttccaaa ccagctacgc ttccccattc agaacgtcct
     6361 gaactaacgg attgagtcaa aggaatctcc tcaatcgtta ctggataatt ttctacaagc
     6421 cagctaatga tctcttcatt ttcttctggt gcaaacgtac aagtcgaata aatcagttgt
     6481 cctttatttt ttagcatttt tattgctgaa gacaaaatct cttgctgacg tttttgacag
     6541 tatagcggag attcttctgt ccactctttt attgcatttg gatcttttcg gaacattcct
     6601 tctcctgaac aaggagcatc aaccacgatc cgatcaaaaa agcccgaaaa atgagggaca
     6661 agttctgcgg gtgcatgatt tgtcactatt gcgttcgaaa ctccccatcg ttctatattt
     6721 tctgataaaa tcttcgcacg tttcggaaag atctcattcg tcactaataa ccctttcccc
     6781 ttcatttgag cagctaattg ggttgattta ccaccgggag ccgcacacaa atccaaaact
     6841 ttttcaccgg gttttgctgc agcagctgtt ccaacgatca ttgcacttgg ttcttggcta
     6901 tattcatacc cagcttgatg gaggaaagac tttccattga cagtgccaag aaatccctca
     6961 ttgctgtagg gagcgggttg taattcttcg ctatggtaag tttggaccat gtccaatcct
     7021 gccggtttta gtggattcca ccgaaatcct tttttcacgc ttccttgttc aagcgcagaa
     7081 aaaaaatcgg atgcttcttc gcctaaaaga agacgatatt ttttgataaa ttgctgtggt
     7141 aacgttgtcg cttcctcctt cattccaatg tttcgttaga cattttacaa tcttttttac
     7201 gaaaaataaa ggtggctgat ctactttttc atgttgctgc ctaaggtgac tgttccttta
     7261 agatattttc caagtattca tccgtcacct cgtttttatc ccaaacagcg ttcatcattt
     7321 caagaaaatc ttgagaagaa tcatctgagc gcaaacttcc caatgcatta agccatacca
     7381 attcaagcga cttttcttct ttgatcttcg tgtgaccttt gacatatgag aaaaatggcc
     7441 gcttaaatag cgaatccatg tctaaatcag attttgcaat gatttcacga atactttcat
     7501 ggatagaaaa aaaatctttc aataagtaga caatgcttaa aacatcatcg gaactgcatt
     7561 cagctaagta gttttcaaaa taaacagtga tttcttctaa tatcttctct tttaacccgc
     7621 tgattgattt gaaatgtgta taaatcgggt atgtagaaca accgcagaac tctgctaact
     7681 ctcttgcagt aattgacttc attccatatt cttccacgta taccatactt ttgaacagca
     7741 aatattcttt actataattt gttactctcc ccatcattct tacctccgtc tcttttcatc
     7801 tacccataaa taaataacat aaataattct aaaaatatta ttgataatta tcaaaacata
     7861 tttagttata tccattaaaa atcaattttt ccgccttaaa aacaagaata tcttgacaaa
     7921 ataccctagg aaataaacaa tagaataaac aaggtaacaa aaaaattaaa taacgttata
     7981 taaaaaagaa ggcgacactc tgtgagaata acacagactg aaatgacttt ccactcacag
     8041 tttttgtcta actatataca aaaacagaat aaaaaggagg tatttatgct aattgaagca
     8101 agaaaaaaag agttacttgt tctacaaatg gtcattcaaa aaaataattg ttctttacaa
     8161 gaattatcca atgacttaca tattccaaaa cggacaatca aagaactgat ccgaaaaata
     8221 aatgtatcac tcaagcaatt tttattgatt gatgaattta tttattctaa tcataaagga
     8281 gagatccaaa ccaaagaaac cgatcaaact aaaaagttag ctgttttttc taagttaaaa
     8341 ttatgctacc taaaagaatc caatcgtttt aactatttga tgttactaat caattatcca
     8401 caaactgctg taccaaaaaa atatttactt gaacaacttt atatatcgcc ctcctatctc
     8461 gaaaaactga caaaacagct caatcattcc ttaaaaaaat tccatttacg gatcctatct
     8521 gtaaaaaatt gctgtactct tgaaggaaat gagttatcta tccgtctcta tctttacttt
     8581 tttctttcag atacatttgg aggtaacgat tggccatttt cctcacttga attaaatgca
     8641 ctaaaaatga acagtacaga tgagcaaata gaaaaaattt caaaacaaga aaaaaatatc
     8701 tacttgctgt taactttatt catattacga aacaaacaac aggcatattt tccaaaaact
     8761 tcttctgaaa tcactgaatt gatggactta ttgcagcata cacatgatta ttcagaatac
     8821 tttacttctt tttcagtgag tcgcccttgt gaagagacag aaacagagag agcctacttt
     8881 aattattttt tctattgttt ttttccaaat caaatctctt ttcgacaaaa acaggagatt
     8941 ggttttttat tttccacaag caaaaacctt atttgtcgac aagtcggtca attgatgact
     9001 tacttaactc aacagtttcc tctcaaccat ttagaaaata aaataccaat ttatttttat
     9061 tttcttgtgt tggcagttgt ttttttcgaa ctgttgggtg aatccagcag tagtttttct
     9121 acactttgct ttccagaagc cacgtccaat cattctagtt cttttataca ggaaaagaaa
     9181 ttaagagaaa aaatcgatac aattttttca aaaaatgggg aaagaaacca aatcagtcaa
     9241 taccttagtc aattgatcca acacttacta caaacagaaa cgaaagagca gttactcatc
     9301 catttgcaga taaccaaaca gtttacagga aattatcatc ttcaaagcca tttgcagcag
     9361 ttatttcgca aagatgctgt taaaattacc gcatattcag aacatgctga tttgatcatt
     9421 acagatcagc atgagaaaat ttcagatgaa acggagactt tctatctgga tacaacgcac
     9481 aatacagtgt tatttggcaa gttaataaaa gcggttcatg aactgtatat gaaaaaaggt
     9541 tatgagaaca aaacaaagag gatgtgacaa aattcttgtc acatcctctt att
//
LOCUS       DAZKCH010000092         9467 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000092 DAZKCH010000000
VERSION     DAZKCH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.093"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..74
                     /locus_tag="ACG84X_002397"
     tRNA            2..74
                     /locus_tag="ACG84X_002397"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="ACG84X_002398"
     tRNA            78..150
                     /locus_tag="ACG84X_002398"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="ACG84X_002399"
     tRNA            155..225
                     /locus_tag="ACG84X_002399"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="ACG84X_002400"
     tRNA            238..311
                     /locus_tag="ACG84X_002400"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="ACG84X_002401"
     tRNA            323..394
                     /locus_tag="ACG84X_002401"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /gene="metK"
                     /locus_tag="ACG84X_002402"
     CDS             660..1853
                     /gene="metK"
                     /locus_tag="ACG84X_002402"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFP9128225.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="ACG84X_002403"
     CDS             1983..3455
                     /locus_tag="ACG84X_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFP9128226.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="ACG84X_002404"
     CDS             3538..4326
                     /locus_tag="ACG84X_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9128227.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="ACG84X_002405"
     CDS             complement(4393..5061)
                     /locus_tag="ACG84X_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFP9128228.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="ACG84X_002406"
     CDS             5176..6888
                     /locus_tag="ACG84X_002406"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128229.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="ACG84X_002407"
     CDS             6891..8663
                     /locus_tag="ACG84X_002407"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128230.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(8745..>9467)
                     /locus_tag="ACG84X_002408"
     CDS             complement(8745..>9467)
                     /locus_tag="ACG84X_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9128231.1"
                     /translation="LKTFTGMIFKFANRRYGLKYNPVNGVSLARKPKTNEEIKKEKDG
                     YLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELISLTESDYDGNKITVSGT
                     YDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIKNNKDKYIFISKNGNPIS
                     IQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPLKAIMDRVGHEDSKTTLK
                     IYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT         2845 a         1585 c         2047 g         2990 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattatttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaactgt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcacgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc agaaaagggg caatttaaat ttctattttt
     8761 cctagttttt ctactagttg attttgcata tttttagttg tatgagtata aatctttaat
     8821 gttgtttttg aatcttcatg tcctacacga tccataatgg cttttaatgg gattcctaat
     8881 tctgtaagta gagaaatgtg ggaatgcctt aacatgtgag aagaaacttt tttatctagg
     8941 tttaattctt tggatactgc tcttaaagat tgattatatg cttgaataga tatcgggtta
     9001 ccatttttag agatgaaaat gtatttatct ttattattct taattaattt gttttcttca
     9061 attaattgat ctatgatttc tttagcatta cttgataatt caatggttct ataagaacct
     9121 gtatttttag ttgttgtttt aatttttaac tcgtaatcat aagtaccaga aaccgtaatt
     9181 ttattaccat cataatcaga ttcagtcaaa gatatcaatt caccataacg tagtccagtt
     9241 aaaaacaaaa atttagtaat taaagaataa cgtgactgtt gatgtgaact tttttgttta
     9301 ctagcaatca tttgaacttc ttcttttgat aaataaccat ctttttcttt ttttatttct
     9361 tcgtttgtct taggttttct tgctaaagaa accccattta cgggattata ttttaatcca
     9421 tatcgacggt tggcgaattt aaaaatcatt cctgtaaaag tttttaa
//
LOCUS       DAZKCH010000093         9325 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000093 DAZKCH010000000
VERSION     DAZKCH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.094"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..75
                     /locus_tag="ACG84X_002409"
     tRNA            2..75
                     /locus_tag="ACG84X_002409"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Ile,seq:cat)
     gene            complement(460..957)
                     /locus_tag="ACG84X_002410"
     CDS             complement(460..957)
                     /locus_tag="ACG84X_002410"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFP9128232.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(997..1806)
                     /locus_tag="ACG84X_002411"
     CDS             complement(997..1806)
                     /locus_tag="ACG84X_002411"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9128233.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            2140..2997
                     /locus_tag="ACG84X_002412"
     CDS             2140..2997
                     /locus_tag="ACG84X_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFP9128234.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            2990..3892
                     /locus_tag="ACG84X_002413"
     CDS             2990..3892
                     /locus_tag="ACG84X_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFP9128235.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            3925..4275
                     /locus_tag="ACG84X_002414"
     CDS             3925..4275
                     /locus_tag="ACG84X_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFP9128236.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            4324..5247
                     /locus_tag="ACG84X_002415"
     CDS             4324..5247
                     /locus_tag="ACG84X_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFP9128237.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            5325..6218
                     /locus_tag="ACG84X_002416"
     CDS             5325..6218
                     /locus_tag="ACG84X_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9128238.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            6256..6819
                     /gene="amaP"
                     /locus_tag="ACG84X_002417"
     CDS             6256..6819
                     /gene="amaP"
                     /locus_tag="ACG84X_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFP9128239.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            6833..7021
                     /locus_tag="ACG84X_002418"
     CDS             6833..7021
                     /locus_tag="ACG84X_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFP9128240.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            7034..7936
                     /locus_tag="ACG84X_002419"
     CDS             7034..7936
                     /locus_tag="ACG84X_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFP9128241.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            7968..8210
                     /locus_tag="ACG84X_002420"
     CDS             7968..8210
                     /locus_tag="ACG84X_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFP9128242.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(8466..8837)
                     /locus_tag="ACG84X_002421"
     CDS             complement(8466..8837)
                     /locus_tag="ACG84X_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128243.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3266 a         1606 c         1805 g         2648 t
ORIGIN      
        1 tgtaccttta gctcagttgg ttagagcaga cggctcataa ccgtccggtc gtaggttcga
       61 gtcctacaag gtacataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
      121 ccaagtaaaa acagcttctt atgtttttac ttggctgttc ttattactgc agatgcaagc
      181 ttttgaatac cgtttaagga agaggttgtg aaatcagcgt tttgacctga gtattagctt
      241 aacaaacgga aaaatagttc ctcatatttt gccgtttgtt aagctaatac cgagggtcag
      301 ctgattgaac accatttaag aaagaggtcg tgagcctgcc gtttcactct gtgtcataaa
      361 aaagccaatc tactttgata gaaaaagcac gtaggactaa aacagttctg cgtgcttttt
      421 ttattgtgtg ttaaatatcg taaatgaaga tagatatttt tatgattcga cgatagagac
      481 gttgaaatct ttcaacagct ctaaagcgga ttctccgtgt tttctactgg agactaacat
      541 tggatcaaca aaaaagtctg cttcaggaaa agcactctgc aggcctatca gattagagag
      601 tacacacaag tttgtttcaa tcccgactac ttcgatctct ttttgttctt ctttgctttc
      661 aaataaagtt tcctggattt cagctaaagt ttcaggtgga atcgtaaagt aatacttttt
      721 aatcactcgt tcattttctt gtggagaaag aagagggatc aattgcaaat cttctcgttc
      781 ttcttctttg tccttcagtt caactggtat atcccgtgtg aagagaatat attcattatt
      841 ttggcgtgct ttagctaatc tttgagcaat acgttctgcc aattgatctg actctggaat
      901 ataaaattcg ctgtttggat caagaatatg attttgcata tcaataataa ctaacatttt
      961 ctttcctcct acattcatat cgtcatttta ttctttttaa tagaagtttt ttaaaatata
     1021 agcaacacca gcttcttcat tcgtcagtgt tacttggttt gcaatttctt ttacttgtcg
     1081 ctgtgcattc cccatcgcaa tactcaaccc gctgtaattc aacatagcaa tgtcgttttc
     1141 ttgatcgcca aaagccatga tgtcactcga ttcgattcca aggtaatccg ccagaaaaac
     1201 aagtgaatga gctttagtga tacctgtagg cgtgatttct aagaaatgcg gatcagagaa
     1261 tactgattgg ataccatctg cttgcagatc tctttgtagc ttctgtagtt tttcttcact
     1321 cttatctgtt aatgctaatt taagatagct aagagaagga tcttccaaca tatttaaaat
     1381 ttgatcaaaa gaatggttct gtaaattgaa atgttcataa taagggtcat ctttgactag
     1441 atttgattca tcgaatgtca gctgatcatc ttgggtttct cggctagcaa tgatggatat
     1501 tttcgcttct tgagcataga agaaggcttt tctcagtgta tcgctatcta tttttgaacg
     1561 tctgagaact ttcgccattt ttccatcctt catttcagca atcagtgaac cattggaaga
     1621 aatcaaatag ccaccgattc ctaattcgga aaaaatatct ttagcagaaa tgctgttcct
     1681 tccggtagcg acggttacga ttccgccatt ttcatcaaat ttccgaagtg cttggatatt
     1741 ttcttctggt atctttccat ttcgatcaag caaggtaccg tctaaatcaa tcgctgctag
     1801 tttcatttta tcttcctact ttctttttac atatctattt tcctgttacc ttaagattaa
     1861 atgagaattt aaaaaaatga aactaacttg ctttgtcatt atgaattttt tcaaaaaaca
     1921 ttcttaagaa aaaggtggct atatatagta gtttttggtc aatacctttg aataaaaagc
     1981 catgaaaaac gaatagttag cgcttaccga tgcgttttgt gataaaaaaa ttttaaaata
     2041 ttcaatgaaa acaaagcata tattttgctt taaaaccaaa tgaggaatat tctagatgta
     2101 gaacaggtta gaaaaagatt agaaaaagga gtgattttga tggagaagag atacggcgta
     2161 gttcctgtgg taactgcttc agacgaaaat tatgctcctt acttgagcgt gatgatcgca
     2221 actgcattag aaaattgcaa taaaacaaga cgcataaaat tttatgtgat tgacgatggt
     2281 ctatcagaat atagtaaaga aggattggaa gaaacggtaa ataaatattc aagtaatgca
     2341 agtatccaat tcctgacagt ggaaaaagat atctacgaag acttcctagt cagtgaccat
     2401 atcacaacta ccgcttactt aagaatttct ttaccaaact tattagctaa agaggattat
     2461 aagaaagtcc tttacttaga ttcagatgtg ttagtactag acgatatcgt aaaactatat
     2521 gatgagccgt taaatggaaa aacaatcggc gctattatcg atccaggcca agtgaaagct
     2581 ttggaaagat taggaatcga ttccgatgac ttgtacttca attcaggagt gatggtgatt
     2641 gacattgatc aatggaataa aaaagaaatt acagaaaaaa ctatccatta cctcagtgaa
     2701 aatggcgatc gaatcatcta tcacgaccaa gatgctttga atgctgtact ttatgaagat
     2761 tgggaacaac ttcatccaaa atggaacatg cagacttcgc tgatttttga acgtcatcca
     2821 gcaccaaatg aaaaatatga acgtcagtat aaagaaggaa atgaaaaacc ttcgatcgtt
     2881 cactttacag gacatgataa accttggaat acgttgaaag atcatccgta taccaattta
     2941 tacttaaaaa aattagcaca cagtactcta acgaaagtag gcgagatcaa tgaataaaaa
     3001 agaaatagca gtagtcgcaa gttgtaacac aaaattcgta ccacatttag ctgcattatt
     3061 tgtctcagta ttagataatt gcaacccgtc taaatttgtt cggttctatg tgattgacga
     3121 tgatatcgat tttgaaagta aacagctttt acgcttctca gtgaaaaacg cacgaatgaa
     3181 ctcagatgtg gaattcttga aaatcaataa agaattcttt acaaatgtgg taatcagcga
     3241 tcgtattcca gaaacagctt attatcgtat tgcgattccg gaattgttcc gcggcacaga
     3301 agttgaacgt atcttatata tggattgcga catgatcgct ttacaagata tctctaaatt
     3361 atggcgtctt gacttcggtg attcaatcgt agcagctgtt gaagacgctg ggttccatca
     3421 acgactggaa aaaatgaaaa tttcagctaa atcaatgcgt tatttcaact caggtttgat
     3481 gctgatcaat gtgaaaaaat ggttagatga aaatattacg caaaaagtat tagatttcat
     3541 cgaacataat ccagaaaaat tacgattcca tgaccaagat gcattaaatg ctatcttaca
     3601 tgaccgttgg ttaccacttc atccgcgttg gaatgcacaa ggctatatca tggcaaaagc
     3661 aaaaaaacat ccaacagcag caggtgaacg tgaatacgaa gaaactcgca acaatcctta
     3721 cattatccat ttttcaggac atgtgaaacc gtggagcaag gattttgaag ggccaacgaa
     3781 gaaatattac gaaaaatatg cagggatgac ggctttccgt tgtgtagcta aattccctaa
     3841 atatccaaaa tatgcaaaag ttcaaccaaa aacagatgta gttgttaaat aatagaagac
     3901 aacaactgaa gagggggagt aggaatggaa attacaatgt ctaaaaatgc agtagagacg
     3961 ttaattgaaa aggttgggga aaatacaaaa atcgcactcg cgcttatcaa tgattccgat
     4021 ccatttctaa gggacaaagg tgcttttgca aaaggcagct tttttcaaat cattcctttt
     4081 gtttcggaat ttggagaata tgcgactaaa atcgagcatc cattattgga catctataca
     4141 tctaaattag agcaaaatta tttcggtaaa cgattgaaca tggacttcaa caaacagctt
     4201 gacagctttt cattagaaaa tgaaatcgca gtactcgatt ataatatcaa attaaagaac
     4261 tgcttcttca gctaatagtt tcgagaaagt ccaaaaagga ggtatacatt gagatactac
     4321 tttgtggatg aagaaaagaa tgtaatagaa acagatgaaa aaaaatataa ttggctcgta
     4381 cttgatagtg caaagcccga agagattgag caagcaatcg aagaattcga gcttcctgat
     4441 gatattttcg taggaaccga atatccggaa gaagtttctc ggatggagcg cctttatgag
     4501 acgaaactag agcatccatt ttctttggta gtgattaatc tagatcagtc agataatcgt
     4561 atcgaaaaaa aattaacgcc aatatctttt gtactttccg ataatctctt gattacttgt
     4621 atcgatagaa aaaccgaatt tgtggatcgg ctgctgacaa agcatggaaa tcatttaaac
     4681 tcgtttgaaa agatcatcac gtatacatta ttagatattt acacccatta cgtgaaagaa
     4741 ctaagagaga tgaaaaagcg aattgacgct ttggataaag cagctcgtaa aacaacggaa
     4801 aatgaagaac tgtataaaca ggcagatctt gaaagagaca tcgtatatat cgatcatacc
     4861 ttaagagatc aacgggaaac aatggatcaa ttatggaatt ctgaaacttt catcaaacgt
     4921 ttagacgatg aacagctact ctatgatgtc catttgagac agcgacaaac agaaaaaatg
     4981 atcgagatct atcgagattt attagagagt attggtgatc tattcaacgg gatgatggac
     5041 aataatctaa atcatatcat gaaatatcta gattcagctg cattaatcat ttccgttccg
     5101 gcgttgttcg cagggatttg gggaatgaat acaggaggat taccgggtaa aagttctgct
     5161 ctaggcttta tactcgtagt ctttggctct ttgatagcag cagtagtttt aggttaccat
     5221 ttataccgga aagattatac aaattaaaga atctatttaa aacaggtatc aaacaaagaa
     5281 atttgttttg gcaatacaat ttaaaaacta ggaggaatac agcaatgaca gaaccaaaat
     5341 taatcgaccc gcgaaacttg taccatacgg agaaatttcc taaacaagat caggatacac
     5401 cagctttaca gcagaatatg attcctgttc ctgattgtgg agaagaatcc tatgaaggca
     5461 ataatcaact agaaaaccgc cgtgtactaa tcactggtgg agattcaggg atcggtcgtg
     5521 cagcagcgat tgcatttgct agagaagggg cagatatcgc tcttcaattc ttcccaggag
     5581 aagaaaaaga tgcagaggaa gtagcaaaat acgtgaaaga tgcaggacgt aagattgtct
     5641 tactaccttt tgatcttcgt gacgaacaag cacctaaaga aatcatagat aaagccgtga
     5701 gtgaacttgg cgggctagat acgatggtac taaacgcagg acagcaaatt tcttgtcagt
     5761 ctattgctga gttaccactt gagcaagtca aagacacatt tatgataaac atcatcgcta
     5821 tgtttgcttt agtgaaagaa gctgttccgc atatcccagc aggaggagca atcgtaacaa
     5881 caacttctgt tcaagcattc aatccaagcg aacatttatt agattacgca gcaacaaaag
     5941 cttcaatcgc taactttacg atcggtttag caaaacagct tgcacctaaa ggaatccgtg
     6001 taaatggtgt agcacctggt ccaatctgga caccattaca actagacgaa ggacaacctt
     6061 ctgattcgat ccctgaattt ggtcagcaaa gtttactaga acgtgcaggt cagccaggag
     6121 aattagcacc agtttatgtt ttcttagcat cgaataaagc aagttatgtt acagcccaaa
     6181 tttacggagt aactggtgga gaagcgatca acttataaga agttgatcgt ttcaccccta
     6241 tgaggaggtg cgaaaatgaa taaaggtgta aaaacgatcg gagtgatcgg aacattactt
     6301 ttgctatctg tgcttttgtt tgcgatacta ttaagtgcaa cctatccatt gccttttcag
     6361 ctagagaagt ttcgattctt ttccatcact aattcatacg tgcaacaata tgtattttgg
     6421 cttgccgttg catttgctat tttgacaatt atcacgttac ttgttttcct gttttatcca
     6481 aaaacaatcg gaaactttct actgaaacat ggtgatgggg agttgacgtt ggataaaaaa
     6541 gcaattgaag gaatggttcg ttctcacttg catgaagatg aattcatcca ttcaccaaaa
     6601 gtaaatgtca aagcaacgaa aaacaagatc gccgtcaatg taaaagggga gttgaaacga
     6661 acttcagcac tcattggtaa aacaggaaca ttgatgaaag aaatcgaaaa tgaagtacaa
     6721 cacatattgg gaacaaaaga gccagtgaaa gtatcggtga aatacacagg ctttgaagaa
     6781 ccagctaaac gaagcaatga ccgcaaacga gtagaatagg gggggaccaa aaatgaaaga
     6841 actattttcg acatacaagc tccctatcat ctttggggta cttggattga tattagccgt
     6901 tttatggatc accgtgggct ttttcaagac cttattgatc ttgatcatgg cagcgatcgg
     6961 cgtcgctatc ggtttttatc tgaaacaaac gaaaatctta gatcactatt ttaaatctta
     7021 ggaggaaaca tccatgaata acaataacaa aaataataac aataaaatga acaaccaaaa
     7081 accagtgtct gcacatccag acccaacgac accaaaccaa tcaaatggtg tgaacgatga
     7141 aaagaacaaa acagcaccag tatctgcaca tccagatcca gtagtcccta acgttcaaca
     7201 aggagtagaa gagaagaaac atgatgcaga aaagcatgca cctcatcatc caggaactcc
     7261 agaatctaaa gttccagaac aacatgatgc aatcgatcct tctaaacctg tggaagagca
     7321 aaaacatcct tctgaccatg cgaaagcaca agaaaaactt agttctgacc acacaaacgg
     7381 acaaggaaaa cttggttctg atcatacaaa taaccaagga aagcatgatt ctgaacagga
     7441 agattcaatg cgcggtgagc tgaattatga agataaagtt gtgcaaaaaa tcatcggaat
     7501 cgcaattgaa caagtagacg gtttattatc tgcaaacggt ggtttcttct ctaatgtggc
     7561 aggaaaactt gtgaatacag ataatgtaac ggctgggatc gaaacagaag tcggtaaaaa
     7621 acaagtagca gttgatatgg atgtcattgt ggaatatggc aaagatatcg aaaaaatctt
     7681 tgaagaaatg caagaagtaa tcggcaaaga agtaaaaaat atgacacatt tagaagtgat
     7741 cgaagtcaac gctaacgtag tggacatcaa aacaaaagaa gaatttgaaa aagatcaaga
     7801 aacggtgcaa gacaaagtaa ctgacgcagc gaaaaaaacc ggtgaatttg cttcgaatca
     7861 aacagataaa gtaaaatcag cagctggaag cggcgcacaa aaagtaaaag aaaatacaga
     7921 accacgggtt cagtaataag gaagtaaaac attaggagga acgaaacatg ggatttattt
     7981 ggtcacttat cgtcggagga attatcggag caattgcagg agcaatcacg aataaaggtt
     8041 cttcgatggg gattattgca aatgtcgtag caggtttagt tggatcagca cttggtcaag
     8101 cattattagg ttcttgggga ccaagtattg caggaatggc aatcgtgcca tcattgattg
     8161 gtgccatcat tttagtacta atcgtatcat tctttgctcg aaaactgtaa aaagactttt
     8221 aaaaagaggt cgtgaaaaag ctgttcttca tcaagtaata agaacagcca aacaaaaata
     8281 gcttctcata tttttcattt ggttgggcat attatcgaag atgcaagctt ttgaacactg
     8341 tttatacgga ataagaggct gtgacaagac ttttgtcaca gcctcttatt tatgcgggca
     8401 aattcccaat tagattttta aaagtttttc cttaaatgtg tctttattga tacagagaag
     8461 cttctttaat aaaacaatgc ctccctaaat tttcttgaga taggaaaggt gaacatacaa
     8521 aataatacga ccactttgaa aacccagatg atccacaaat ggatcgtatg atactgatga
     8581 agtaaaaagc aatggatcag aaactcaaag agattgaaaa agacaaggaa gaaataatat
     8641 ctctttttta ctcttgtctg ttttagccaa taatagctcg taaagtaatc tagacaaaca
     8701 aatagaagta aacaaagttt cgtaagagca gcaatcgtat catgttgctc tgctagacga
     8761 ttgacgagca ggaaaaatgt tggtaatgga atatagatca cgagtaatga aagaaaaaag
     8821 taaacaataa atggcatact attcctccta attgtgtgag ttcgccctca ttttaaaata
     8881 acgatatttg tttgtgaagc tttttcgtgt cgtaacaaat gttatctaat gtatttttaa
     8941 ataaataatc attattatca aaataatgtt aaaaataaaa aagaattgtc catcactgtt
     9001 attcaaatca ttttatcaaa actacatagt aaatgttaaa aagcaacatg acataatata
     9061 tagaaggctt tacagtatat atgggagctt actaaaaaag aatggagtaa gagttaacac
     9121 aatgggccat tagctgaagt tttaagcact tcaaggtatg aaacagaatg gcctgtaata
     9181 ctacatgatt atttagactg ctcaaactgc tatcagtctg gtggaatgaa taaagtatta
     9241 tactaaaagc agatccaact acaacgtaac aggaaaccag ttgtatcagg aaaagtgata
     9301 gtacatggag aagaaaaggc cccct
//
LOCUS       DAZKCH010000094         8875 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000094 DAZKCH010000000
VERSION     DAZKCH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.095"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            278..787
                     /locus_tag="ACG84X_002422"
     CDS             278..787
                     /locus_tag="ACG84X_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9128244.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="ACG84X_002423"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="ACG84X_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9128245.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLTPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="ACG84X_002424"
     CDS             2322..3302
                     /locus_tag="ACG84X_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9128246.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="ACG84X_002425"
     CDS             3424..4842
                     /locus_tag="ACG84X_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFP9128247.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="ACG84X_002426"
     CDS             4913..6382
                     /locus_tag="ACG84X_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9128248.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="ACG84X_002427"
     CDS             6392..6859
                     /locus_tag="ACG84X_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFP9128249.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /gene="scrK"
                     /locus_tag="ACG84X_002428"
     CDS             6895..7767
                     /gene="scrK"
                     /locus_tag="ACG84X_002428"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFP9128250.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7849..>8875
                     /locus_tag="ACG84X_002429"
     CDS             7849..>8875
                     /locus_tag="ACG84X_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9128251.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDL"
BASE COUNT         3053 a         1323 c         1788 g         2711 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga cccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttt caattagtaa ttgaagggac gcctaaaagt gaaaaaaaaa
     7861 atgaaagatg aagtattaga gtatatcaaa aataatttaa agtattacga tttttctgct
     7921 caagatattg caatgaaatt ttgtattaaa agaaatgtcg cttcccacta tttgaatcag
     7981 ttattttcag atggaaaatt actaaagaat gattctgtta gaccagtaat gttcaagtat
     8041 aatcaacaaa agccaaaaga ctgcttttct aagtttattg gagcagacat atctttgaaa
     8101 tccactatag ataaatgcaa agctactgta atgtatcccc ctaatggcct cccattaata
     8161 ataaaaggaa acagtggcgt tggaaaaagt tttttagcaa gtttgatcta tcagtatgct
     8221 cttgatagaa aagtaattca taatgacgca aaatttgttg ttgtgaattg tgcagattat
     8281 gcaaataatc cagagctatt gtcagcagtt ttatttggat ataaaaaagg agcctttact
     8341 ggggctgaaa aagatactgc agggatgcta tcttctgcta atggaggata ccttttttta
     8401 gatgaggttc acaatctaag tgcagaaaac caagagaaat tgtttcttct tatggattct
     8461 caaaagtatc gtaaacttgg tgaaagtgtg caatgggagt atgcaaatgt tcgccttatc
     8521 ttagccacaa cagaagataa aaatacctct ttgttagcaa cttttagaag acgcatccca
     8581 gctgaaatca ctctgccaga ttacaataat agaagtacat ctgaaaaaat tcaattatta
     8641 tttgaatttc ttaaagatga agcaattaca attgattcaa aaatattttg ttcgattgaa
     8701 ctttttactg atcttttatc gaaaacattt gaaggaaatg ttggagaatt gaggaatgaa
     8761 atcaagcttc tttgtgcaga aggttattta ggaaataaga gaaagtcttc aatttattta
     8821 ggggacaaac tagacagcgg tttttggata gatccagaaa ttagtataga tttaa
//
LOCUS       DAZKCH010000095         8711 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000095 DAZKCH010000000
VERSION     DAZKCH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.096"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(309..2690)
                     /locus_tag="ACG84X_002430"
     CDS             complement(309..2690)
                     /locus_tag="ACG84X_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFP9128252.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2680..3327)
                     /gene="recU"
                     /locus_tag="ACG84X_002431"
     CDS             complement(2680..3327)
                     /gene="recU"
                     /locus_tag="ACG84X_002431"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFP9128253.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3391..3930
                     /locus_tag="ACG84X_002432"
     CDS             3391..3930
                     /locus_tag="ACG84X_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFP9128254.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4020..4439
                     /gene="gpsB"
                     /locus_tag="ACG84X_002433"
     CDS             4020..4439
                     /gene="gpsB"
                     /locus_tag="ACG84X_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFP9128255.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4461..4828
                     /gene="rnpB"
                     /locus_tag="ACG84X_002434"
     ncRNA           4461..4828
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACG84X_002434"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5037..6203
                     /locus_tag="ACG84X_002435"
     CDS             5037..6203
                     /locus_tag="ACG84X_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFP9128256.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6249..7745
                     /locus_tag="ACG84X_002436"
     CDS             6249..7745
                     /locus_tag="ACG84X_002436"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFP9128257.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7826..8509
                     /locus_tag="ACG84X_002437"
     CDS             7826..8509
                     /locus_tag="ACG84X_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFP9128258.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            8518..>8711
                     /locus_tag="ACG84X_002438"
     CDS             8518..>8711
                     /locus_tag="ACG84X_002438"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128259.1"
                     /translation="MTEVVSSKIFRIIFRKSYFWNTVYQEVVSLPFSSESQGTISKNS
                     FSCLMNIVTCDSELAGEHRL"
BASE COUNT         2743 a         1575 c         1845 g         2548 t
ORIGIN      
        1 attcaaaacc atatattgta ttttttattt gataataaca atgggattat taagaagtgg
       61 cactaaataa aagactagtg tgtatttagc cgatttaatt ataaacaagt aaatggataa
      121 agtatatgta atgataaaag aaaaatggat tttctaattt ttaagctaaa tgttagatca
      181 cacatgtata tgctggatag tcttataaaa aatcatgtaa tacagcttgg tacatgattt
      241 ttatttgtag ctgtttttta catagacaca aaaaagaaac cacgcttgta gacgtggttt
      301 cttttttact atctgtttcc agaagctgag gtgctgctgg atggtgtatg gtcatttgca
      361 gcatccgctc cgctagttgc tggctcactg gaagaagcag gaggagcaga tgaagacggt
      421 gtcgagcttt cttcggatga agaagaagga accgttgttg aagacgctgg ctcgcttgtt
      481 tctgctgtcg tgctttcttt tgaggactca gcagttgatt cgctttgact agtagagcta
      541 gagctttgag tcgttgtctc tgttgttgag cttccaggag tctggacata gctggaagat
      601 ggaatagttg ttgatggtgt aattgcattc gatctagctg tatattgatc tttgtagtac
      661 agttcaccgc ccacacgaat taatccgctt ggcatctccc agtctgtatt tgtcacgtta
      721 gctgaaacat actgcataag ctcgcgataa acatcagagg ctacgtgtga cgattctgaa
      781 gtgacaggcg tcattttttt attgtaacct gtccacacgg aaatcgaata atttggcgta
      841 tagcccgcaa ataggatatc tggatacacc ccagaagaaa taccaagttt tgcatactcg
      901 tcatctgtgt aattggatgt tccggtctta ccggcttgat ataacccagc gatttgcgca
      961 ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt ctgtgatcat ataagctgtt
     1021 tctggagaca tggctgtttt tccatctggc tcataagttt cttctgttcc gtcttggaag
     1081 acgattttat taacatattg aggtttgtaa taagtccctc cattggcgaa agccgcatag
     1141 gctgctgcca tttttaagga agaagctccg tattttgtcc catcttgttc ttccgtatta
     1201 ctagagatcg cattcgattg atggatcgta ctgtattcga tcccaagatt ttttaagaaa
     1261 gaagccactt tatctgaacc gacttcattg aataatttga ctgctggaac attacgggat
     1321 aagtaaagtg cttggcgtaa agtaatggtg cccatatatt gattatccca gtttcctaca
     1381 ggagtcgaag tcccttcata gttatacggt gcgtcagtaa tagtttttcc agtagaatat
     1441 ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt tcatcgtaga accaaaatca
     1501 cgggaagtat tcactgctaa gttgttgcct aaagttacgt cttctgcgat gtgacgtccg
     1561 ccaatctggg cttttacttt cccggtattg gtgtcgataa gggtggaggc aacttgcatc
     1621 tcgtcgtctg ggtaagagac atactgatcc gtgttgacga tatcatatag tttcttttgg
     1681 gcgtccagat ccaaattcgt ataaatctct aaaccgtctg tgtagacatt cttatctgtt
     1741 ttttcttgta cttcattgat gacttctttg acataattat cgacgatctt agtattgtca
     1801 tcggattgag ttagttcttg cagaccatcc gttaccggta cattaacagc ttgatcatat
     1861 tctgtttgag agattttttc gttttgaagc atcgtataca aaacagtatc tcgtcttttc
     1921 ttcgcctgat ctggataaac ataaggatca taggcggaag gggcttgagg catcccagca
     1981 agcaatgctg tttgcggtaa agaaagttct gataatttct taccaaagta catctcagaa
     2041 gctgtctcca tcccgtacaa gccgtttgac atatacactt tatttacgta gtaggtcaag
     2101 atctcttgtt tcgatttttt ttgttccaat cttacagcca tccacgcttc ttgggccttg
     2161 cgtttcagag tctgatcctc ggcactggtg gagaagaagg aaagtttgat caattgctgt
     2221 gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt tagagagggc agaaccgatg
     2281 atccgaatag ggtcaacccc gatgtgttta taaaaacggc gatcttctac cgacacgatc
     2341 gcatcttcta atgttttcgg taattcattc gcagaaattt tttcacgctt ttctgcgcct
     2401 aaatcttcga atagttcgcc atcttgtgta tatagtttgg aagatacggt agcgtctaat
     2461 tttttatccg tcaattcggg cgcatctttt gcgtaatacc agaaaagtcc tacacctgct
     2521 aaaaagagga tacagaaaaa tgagagtatt cctaaaagga tcttgataaa taatcctttt
     2581 ttatgtgttc cagaggactt tccagaacct ttgccagaat tcttcttcac actcttttta
     2641 ggagtaggct gtttctgtcg tctagagctt ctagtttgtt catttgccat tcttgctttc
     2701 tccttcaata gataatgttg ataaatagaa gtcaaccgcg tccaaataag gaatccgcgg
     2761 agaaatacca gttttgatct ctattcctag ttcttcgatc aaagataaag gtagtgattt
     2821 gcgtcctttt tccttttggg cgtcccagta agcaatcaaa tgaacactat tcaaataaaa
     2881 acagcgcttc aaagacgaaa accataacaa gacaaagcag accccatttt gttcgaggca
     2941 tgctttcata tgttcgattt gatgggcatg gaagttttta aagggaaaag atgttttgtt
     3001 cttggtttct tttgcttcaa agtccaagta aaagcctcga tagacgccat tatagtctgt
     3061 agttgaggct tgggtaaagt aggcttcctt gatcacagca gcacttctct taggatagtc
     3121 tactttcacg atttggatag gggtaggctt tttatggata accgccaacc cgcgggaaag
     3181 ataatattta ttactttcat tgattgcttc ttcaaagcgc atcccccgat tgccgaattc
     3241 agtgatctga tttctttttt cttgaatttt ttcgacggga gaggcattct tataataagg
     3301 ttggccattt ggatagcgca ataccatctt taatcacact cctaggccac attatagcaa
     3361 aaaagcggat agaaagaaaa ggaatctgag atggataagt caaaagtaat ctatgtgtct
     3421 gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg atcctaaaat ccaagttgtt
     3481 aaaaatgttt taaaaaaaga actccatcag ttagcagaag aagggctgga atgggtactt
     3541 gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa tagtagcgga attgaaagaa
     3601 gaatatccgg aactatctct tggtattttg tatccttttt ctgattttgg taataactgg
     3661 aatgaaggga accaagaaaa aaaacaatta gcagaacaat tagcagatta tgtcgaagct
     3721 gttagccatc aaccctacca atcacctagt cagctaaaga atcacactcg ttttatactt
     3781 gagcatacag tgggctgtct gctgatctat gatgaagaat tccctggaaa aacgaagtat
     3841 ttttttgaag atgcacagaa ttaccaagca gatcatccct acgaaattcg gctgatcagt
     3901 atggacgatc ttcaaaattt tagtgaataa tcgatattgt gtttgattta tcaacttttt
     3961 tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat gaaaactaga ggtgtaaata
     4021 tggcgaattt ggtttatagt cctaaagaca ttttacaaca agaattcaaa acaaaaatgc
     4081 gcggctatga tcccgttgaa gttgatgaat tcttagacaa tatcatcaaa gattatgaaa
     4141 cttacagcaa agaactcctt gctttacaag aagaaaacga tcgattgagt gcaaaagtag
     4201 ctcaattatc taaaactcaa ggagcagctc aaacacgcgt gcaacaaaca gaggcaccaa
     4261 agagcgcagc agtgaccaat tttgatatct taaaacgctt gtcaaatctt gaacgtgaag
     4321 tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa accagcacaa cctaatccaa
     4381 ataactacac aaatgcagac acaagcttag atgataatga aaaaacacgt caattttaat
     4441 ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc tgacttgatc aggctgagga
     4501 aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg tgcttagcga aaccataagc
     4561 taaggtactc tttggagtaa cggcaggaaa acaagctaag gcttcggcta tgcttaagta
     4621 tccttgaaag tgccacagtg acgaagcggc tggggaaacc catccggtgg aacgcggtaa
     4681 acccctcgag cgagcaaccc aaacaatggt aggggcgctt tttgtctgga agaagaacag
     4741 gacaaaaagg cagtataact gcagatagat ggttaccgct ttgttttttc tccctggaaa
     4801 agcaaagtac agaacatggc ttatagaaaa ccgcaaacat cagggaatta ggtcgtgaca
     4861 aaagtaatgc gttataagaa acaagaaaaa catttgaaag ctatttttca atacttcaga
     4921 tgaatcgttc ttattacaaa acaaactttt gtatcaccgg ttattcggaa tttgagtaaa
     4981 agtgtggggt aggactgatg tcccacctcc tttttttata aataaggaga ttgtgtatgg
     5041 aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag cgggctagaa gcactggttg
     5101 gtaaagaatt aagagatctt ggaatcgaat gccaagttga gaacggacgt gcacgttttg
     5161 aaggaacaat ggaaacgatc gctacagcta atttatggtt acgtacagca gatcgagtaa
     5221 aaatcgtggt tggggaattc gatgcgtata cgtttgatga attgtttgaa aacgtaaaag
     5281 cattgccttg ggaagatttt cttccactag atgcagcttt tcctgtagct ggaaaatcga
     5341 tcaagtcgaa actatatagc acacctgatt gccaagcgat cacaaaaaaa gcaatcgttg
     5401 aacgtctccg tacctattat caccgtccag cttctgtacc actgacggaa actggcgcac
     5461 attttcagtt ggaagtagct ttgctgaaag accatgtgat ggtaactctg gatacgacag
     5521 gaccaagttt attcaaacgt ggttatcgct tagaaaaagg tggagcacca ttgaaagaaa
     5581 acatggcagc agcacttatt atgttgacaa attggcgaaa agaccgtcca ttttatgatc
     5641 ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt aataggccat aatatcgcac
     5701 caggattcaa tcgtgagttt gcttgcgaat cttgggattg gttcagtcaa gaaatcatgg
     5761 aaaatgttcg atcagcagcc gaagaaaaag cagattatga tattgaatta gatattactg
     5821 gttcagatat caatggacgg atgattgaaa ttgccaaagc caatgcagaa gaaatcggat
     5881 taggctcttc gattaccttt aagcaacaag cagtcaaaga cttcaaaacg gataaagaat
     5941 acggggtcat cgtggctaat ccgccttacg gagaacgtct aggagaagaa gaaactgttc
     6001 ggaaattata taaagaaatg ggcgatgtat tccgtccatt aaaaacatgg agtaaatata
     6061 tcttgactag cgacttagcg tttgaggaat tttacggaca aaaagcaacc aaaaaaagaa
     6121 aattgtacaa tggtgcattg cgtacggatc tattccagta ttggggaact cgtccgccta
     6181 gaaaaaaaga gaaagacgaa taatcttact aattgattca ttcaattgga tgtttggagg
     6241 aatagggaat gaaagaaaaa gagtttttac aagaagtaaa agaaatcaat cttctacaac
     6301 aagctttagg aatcctcgat tgggatacac aaacaggtat gcctgaaaaa gctagtgcat
     6361 accgaagtga agtagacagc tatctttaca gcatttattt ttcaaaaaaa atcggtccaa
     6421 aaatcaaaga agccattcgc tatttttctg aacatccgga agaattgtcg gaagttggaa
     6481 ctgccgtttt tgccaaagta aaagaagagt atgatttgga acatcgcgta ccggaagatc
     6541 ttatgagaaa atatacagct gccgtttctt cagcacacgg acaatggcaa aaagctagag
     6601 aaacacaaca attttctgat tttcaacacg cattgaatca aaatattgaa ttaacaaaac
     6661 agttgatacc ttactggaga aaagatgaaa agacgaatta tgatgttttg ctgaatcaat
     6721 acgaacccgg gatgactgtc gaaatccttg ataaggtatt tgatcagctt aaagaaggaa
     6781 ttctttcgat ccgccgtacg ctccaagaaa aagggactga acctgaaaca gactttttaa
     6841 atcggagaat gacgaaaaaa caacagaaga gatttgtagt gaaagtaatc gaacaacttg
     6901 gttatgattt tagtcgtggt cgtttagatg acactgtcca cccatttatg actggaatta
     6961 atccgaatga tgcacgaatc acgacacgat ggaacgaaac agatttcaaa atggctgttt
     7021 ttggagtgat ccacgaggct ggtcatggta tgtatgaaca agacatcgat gataaatatg
     7081 cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca tgaatcacaa tcgttgttta
     7141 acgagatcat tattggaagt agtcgcagct tctggaaaaa gcaatatcct ttctttcaag
     7201 aatgtgcaga aggaacattc gatgatattc cttttgacaa attttatcgt tcattgaacc
     7261 atacaaaatc aagtttggtt cgtatcgagg cagacagttt gacttaccct ctccatatca
     7321 tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg ggtagatgtt gctgaactac
     7381 ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat acgaccaaca aatgatgtgg
     7441 aaggcatcct acaagacgtt cattggtcag gtgcaagctt tggttatttt ccctcttatg
     7501 cattagggta catgtatgcg gcacaattac ttcattcttt gcagcaagaa atagatgtgg
     7561 aaaatgttct agcgtcagac gattattctc caatcaaaaa ctggatgtca gagcatatcc
     7621 atcaatatgg tgcatctaga aaaccaaatc aattaatcat ggatgcaaca catgaaccgc
     7681 ttaatccgca atacctgatc gactatatga aagacctgta ttttaatgta tatcaggtaa
     7741 aataaaatac aatttacaaa gatagctgaa attcatctaa tctatagatg ttttcagcta
     7801 tttacttaag aaagaagtgg aacgaatgga taaattacaa gtgatcgctg attatagtat
     7861 ggaccaatta gcgcatgatc aaacaggaca tgggagcgat cataccaaaa gagttgtcaa
     7921 gttagctgaa aaaattttgg agacggaacc gcaggcagac cgctttgtga cgcttgcagc
     7981 agcttaccta catgatacga ttgatgataa agtcgttaaa aatgagaacg aggcaaagca
     8041 acagcttcgt gtattccttc gctctttgcc aatagtagag gaacagatct cgatgatttt
     8101 ttccattatc gaaaatatgt ccttttctaa aaatctctct gaagcggccg aactatctct
     8161 ggaaggtaag atcgttcaag acgctgatcg tatcgaagca ttaggagcaa tcggcatttt
     8221 gcgtactgct tatttcggcg gtggacatgg gcacccgatt tttgatcctg aactgtatcc
     8281 gcaaacattc aaggacaaag aaaattaccg aaaaggcacg acagtgatca atcattttta
     8341 tgaaaaactg ttcttgctgt ctgataaaat gaatactgat tacggatatg aagaagccaa
     8401 acgaagagaa accttcatgc gtgaattctt agaagaattt tttctggaat ggtctattga
     8461 cgatgaaaat tttactccag acaattggat caaaaataac aaaaaatgat ggaggttgtg
     8521 acagaagtgg tcagctccaa gatatttcgg atcattttcc gtaaaagtta cttctggaac
     8581 actgtttacc aagaggtcgt gagcctgccg ttcagctccg agtcacaagg aacaatttca
     8641 aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg attcggaatt ggcaggagaa
     8701 caccgtttat t
//
LOCUS       DAZKCH010000096         8642 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000096 DAZKCH010000000
VERSION     DAZKCH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.097"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(49..495)
                     /locus_tag="ACG84X_002439"
     CDS             complement(49..495)
                     /locus_tag="ACG84X_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFP9128260.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(522..698)
                     /gene="rpsU"
                     /locus_tag="ACG84X_002440"
     CDS             complement(522..698)
                     /gene="rpsU"
                     /locus_tag="ACG84X_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFP9128261.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(860..1288)
                     /locus_tag="ACG84X_002441"
     CDS             complement(860..1288)
                     /locus_tag="ACG84X_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFP9128262.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            1380..2240
                     /locus_tag="ACG84X_002442"
     CDS             1380..2240
                     /locus_tag="ACG84X_002442"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFP9128263.1"
                     /translation="MSSDSTEIITFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(2334..2684)
                     /locus_tag="ACG84X_002443"
     CDS             complement(2334..2684)
                     /locus_tag="ACG84X_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFP9128264.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(2700..4427)
                     /locus_tag="ACG84X_002444"
     CDS             complement(2700..4427)
                     /locus_tag="ACG84X_002444"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFP9128265.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            complement(4640..5566)
                     /gene="trxB"
                     /locus_tag="ACG84X_002445"
     CDS             complement(4640..5566)
                     /gene="trxB"
                     /locus_tag="ACG84X_002445"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFP9128266.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(5711..7144)
                     /locus_tag="ACG84X_002446"
     CDS             complement(5711..7144)
                     /locus_tag="ACG84X_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFP9128267.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(7144..8547)
                     /locus_tag="ACG84X_002447"
     CDS             complement(7144..8547)
                     /locus_tag="ACG84X_002447"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFP9128268.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
BASE COUNT         2334 a         1943 c         1486 g         2879 t
ORIGIN      
        1 gaatttcttc accaacactc attgacgaag agcctttaaa tgataaaatt aagattgtaa
       61 tagttctttc acaatggcat ttacttggtt tccatctgct tttcctttga ctttaggcat
      121 gatcgcaccc atgactttgc caaattcttt cattgatgaa gcaccagttt gtgtgattgc
      181 ttcttgaaca agttgtcgaa tttcttcgtc ggaaagttgt tccggcatgt atttttcgac
      241 tatcacaatt tcacttttta ctttttcagc taaatcgtca cgtcctgctt cttcaaactc
      301 atgcaaagaa tcacgtcgct gtttcatttc gcgagacaac accgttaatt cttcttcttc
      361 tgtcaagtcg tgaccttctt taatctgctc gttttgtata gatgacttga tcattcggat
      421 gacttgtaaa gattccttat ctttcgcttt catcgctgtt ttcatgtcat cgtttaatct
      481 acttagtagt gacacactac caactccaat tcatcacaga actagaattt tttgcgtttt
      541 ctagctgctt cagatttttt cttgcgtctt acacttggtt tttcgtagaa ttcacgttta
      601 cgagattctt gtaaagtacc cgcttttgac acggaacgtt tgaagcgacg aagagcatcg
      661 tcaagtgatt cgtttttgcg aacgactgtt tttgacatgt taattccctc cctccgagct
      721 taaaaagtaa ccgtaattgt tattgaaata tatctcaaaa aacaagactg tcctgtaaat
      781 attatatcta atgctgtttt gaccgtcaag gaaatcttgc ttttttttaa aattatcaaa
      841 tgttatttta tttaaatcct tattgacaat tttcacatct tccgaaaatc tcgaatctat
      901 gcccttcgat cgtacatcca ccgagctgtt cttcgaaata attcattgga cacatatgga
      961 tttctttcgt tgttccgcac accgtacaga taaagtgatg gtgatggccg atttcccctt
     1021 gacagcaatg aaaacgaaac ttcatctctc catttaaatc ggtttcttcc agtaaatcga
     1081 tttctgcaaa atcatggaga tttcgataaa tcgtatcgta acttactcct ttgaattcct
     1141 gattcatata gtcaaaaact tctttagcgg atacgtagcg attgcgcttc actaaataag
     1201 ttaacaatgc ttctcttttt ttagtatatt taaaaccgtt atttttcaat gtttctagtg
     1261 attgttcaat caatgtctgt tttttcatga cttattcctc caaatcaaaa tgattacgaa
     1321 gtacacattc tagagtatgg tataataaac ataaaaaaaa tgcaagtgag gttttatcca
     1381 tgtcttccga ttctacagaa atcattactt tttttgtcat ctctgactct gctggagaaa
     1441 ctgcgacaaa attagcgcaa gccactatgg cccaatatcc taccgttgag ttcaatttat
     1501 tccgcagaac atttgtgaca gatgagaaaa cattgatgca ggcactgcaa gatgcactaa
     1561 aagaaaaagc ccttgtccta cacacattga tcaatcaaga attgatcgag atgacgcgtt
     1621 ctttttgtga agaacatcaa ttatttagtt ttgatgtgat gactccgccg atatcagaaa
     1681 tcgagcgctt aactggtatc aagcccattc ggcaacctgg cgcccttcat ttattgaatg
     1741 agaactattt caaacggatc aaagcaatgg aatttgctgt aaaatacgat gacgggaaag
     1801 atcctcgtgg gtttctagaa gcagatgtcg ttttgctagg cgtatccaga acttccaaaa
     1861 cgcctttgag cttgttttta gctaacaaaa atttaaaggt tgccaatcta cctttgatcc
     1921 cacaagcaca tattcccaaa cagctttggg agatcgatcc taaaaaaatc gtgggactga
     1981 cgaataaccc agatatttta aacaatatcc gtaaagaacg gatgcgctct tacggattaa
     2041 atcctgatac tgcttattcc gatatcgaaa aaatacgagc tgaactcgat tttgcgaatg
     2101 atctttatga aaaattgggc tgcgtagtaa tcaatgtcgc ttctttatct atcgaagaaa
     2161 cagcttcact tattttgaat gctttagacc tagaagatca tagttattat ggaactgaaa
     2221 ccaccgaaga aacagactaa cagtttttct tgtctttttc ttaaaaaaac tggactgtgt
     2281 cagcgaagaa gattcgttga tacagtccag tttgtctcta tttgcaccta tcgttattga
     2341 tgttccacat gtttgagcgt ctggttcaaa atatccagta cgtgagaatc atcaagacta
     2401 tacaaaatcg cttttccctc acgatgggac ttgacgacat ggttttctct taataaacgc
     2461 agttgatgcg atacagcaga ttgttccatt tctactgctt gggtgattgc tgtcacattt
     2521 tgttccccgt ctttcagata cagcagaatt ttgagacgag tggggtcact caacattttg
     2581 aatagttggc tgactttctc tacttttgtt ttttgcgtgt ctggcaatcc attcacctcc
     2641 aacttgaaaa aagactgact tctaaagttt accacttttt ccatcagtct caagtttttt
     2701 tattcttctg tcattttttt gataatcgct tcataagcgg ctactttttc agctgcgtct
     2761 tctgaagagt ttccttttac accgatataa aatttgattt tcggctcagt tcctgaagga
     2821 cggatagcga tccagccatt ttcttccagc gtatacttca atacgtcaga tggcggtgtc
     2881 gttagttttt ctacgtttcc ttcacggtct gttctcgtca actctttgaa gtcttctgtt
     2941 tggatgactt ttgctccggc aaattctgtc ggtgcttctt cacggaattt ttccatcaaa
     3001 gcagagattt ttgcagagcc ttcttgtccg ctcattgtca cagaaatcgt tttttctgcg
     3061 tagtagccat atgtttcaaa aatcgtttgc aagccgtcat acaatgtttt gccttgtttt
     3121 ttatagtaag ctgctacttc tgctaataag agcaatgctt gaatcgcgtc tttgtcgcga
     3181 acgaaaggtt taactaaata accgtaactt tcttcgaatc cgaacataaa agtatgggaa
     3241 tgatcttctt caaattgttg aattttttca gcaatgaatt tgaatcctgt caatacattg
     3301 aacatggtag ccccatagtg ttccgcaatt gctgtaggca attcgctaga aacgattgat
     3361 ttcaataccg ctgcattttc aggtaaagtg cctcgcgatt ggtgtgcttc caaaatatat
     3421 tgagcaaaca gggctccgat ttggtttcct gtcaatactt cataggagcc atttggcaaa
     3481 cgaacggctg cgcctaaacg gtctgcatca ggatccgttg caatcagtaa gtcagcgcct
     3541 tctttctcgc caagtcgcat cgcatactcg aaagcagagt gttcttctgg attcggtgat
     3601 ttgactgtag tgaaatccgg gtctgcgaca gcttgttctg gaactagtac gaattgttcg
     3661 aatccagctt gtttcaacgc acgttcgccc aacatttttc ctgttccgtg aagtggtgtg
     3721 tacacaagct tcaaatcttt acccattgtt tccaccaatt catgatcaat cgttactgct
     3781 ttgatttctt ctagataagc ggcatccact tcttctccga tgatcgtgat caatccgcta
     3841 tgttcagctt cgtcgtcaga taatacttca acttttaacg gattgctgac ttcacggaca
     3901 tatttcgtca atgcatctgc gtctgcagga ggcatttgtc ccccatcttc tccgtagact
     3961 ttatatccgt tgtaagctgc tggattgtgg gatgcagtta ccatgattcc cgcaaacgtc
     4021 ttcaaatgac ggactgcaaa agaaagctct ggtgttggac gtaaactttc gaatacataa
     4081 gaagggatat tgtgatgtgc taatgttttg gctgcttcca tggcaaattc tggtgattga
     4141 tggcgtgagt cataagcgat agcgacacct cggcgttttg tttcttcacc ttgtgtatcc
     4201 atgaaacgtg caagtccttc tgttgcttgt cttaccgtat agatgttcat tcgattgatc
     4261 ccaggtccta agattccccg catgcctgca gtaccgaatt ccaacggtgc ataaaaagca
     4321 tcttcaagtt tttcaggatc ttcacccaga tcatttaatt gtttttttaa gttttcttct
     4381 aaattttctt catgtaccca ttgttcatac acttgttccc aagacatgaa aataacacct
     4441 ctttctgaaa tatggttctt aataagtata gcattcactt attagatatg aaagtatgag
     4501 gaccaaaaaa cgcttaaatc aagaaaagat tcttttatca agcacggtta caagtattcg
     4561 cataaatcgg attcagtaga tttcacgcaa aaaaaagagt aaaagaacaa ttgaaaccgt
     4621 tctttcactc tttttaaact tatgcagttg tttcttctaa agattccaag tatttataca
     4681 cttgttgtcc agcaatccca ccatcaccaa cagcagtagt gatttgtcgc aaatcttttt
     4741 cacgaacatc tccgatggca aaaacgcctg gtatattcgt cttcatttcg ttgtctgttg
     4801 gaatccagcc ggcttcgttc gtcaacccag cttctctaaa tggtgcagtt aatggatcca
     4861 atcctacata gatgaatact ccgtctgctg ccaaatcaaa ctcattgcca gttttgacat
     4921 tacgtgcttt cacacctgtc actaccattt catttccaac gatttcgtca acgactgtat
     4981 cccacataaa ggaaattttt tcattcgcaa atgcacggtc ttggatgatc ttttgtgcac
     5041 gtaattcatc tctacggtgg acgatgacta cttcagaagc aaattgtgtc aaatagatgg
     5101 cttcttctac tgctgagtct cctcctccga tcactactag acgtttgtta cggaaaaatg
     5161 caccatcaca aactgcacag taagaaacgc cacgtccagc aaattcttcc tcgccaggta
     5221 cgcctaattt acggtggata cagcctgttg cgataatgac tgtttttcct tcgtaagttt
     5281 tatcttcaca aataacttct ttgtggctgc cgtgatcctt gatatcttgc acgattccat
     5341 aagcattttc tgtcccaaat cttgaaacac cttcatacat cttataagct agatcaggac
     5401 ccatgattga atcgaaacca ggatagtttt cgatttctgc cgtattgttc atttggccgc
     5461 caggagcgcc ttgttcgatc atcaatacgg ataagtttga acgtgaagca tataaagcag
     5521 cagtcatccc agcaggccct gcgccaataa cgattacatc atacatatgt agattctcct
     5581 ttacttaatc aagtaagcat actttacagc caatgcgaaa aaaagtctat tgttctgctt
     5641 gcgtttctcg aatagcttta ttatactcga aaaatccgct gaaaaacaat agacttttat
     5701 aaatcattga tcaatcgttc gaaagatttt ctccatttga atcaattact tttttatacc
     5761 agttgaatga tttcttcttc gaacgggcta atgtgccatt tccttcgttg tcacgatcga
     5821 cataaatgaa tccgtacctt ttcttcatct cacctgtacc agctgatact aaatcaatac
     5881 atccccaagt cgtatagcct aatagatcga ctccatctaa ttctactgca tctttcattg
     5941 cctggatatg tgctgccaga tagtcgattc gataatcatc ttccacataa ccattctcat
     6001 cgggcgtatc gactgcacct aagccgtttt ctacaataaa tagtggtttt tgataacgat
     6061 cataaatatc attcatcgtt attctcaagc ctaatggatc aatttgccaa ccccattcac
     6121 ttgcttccag atatggattt ttgacagaag caaagatatt tcctgcagtc tgttccaaga
     6181 gttcgttgtc agtagtcgaa actcgagaag aataataaga aaaggagata aaatcaacag
     6241 tatgttcttt cagcaatgcg gcatccccag gttccatttt gatctgaatg ccatttcgtt
     6301 ccatttcttt caatgcataa gcgggatatt ctcctcgtga ctggacatca atgaagaaat
     6361 aattttctcg atctgacttt ctagaagccc aaacatcttc aggattgcaa gtgtatggat
     6421 aatatgctcc tgctgccagc atacagccta ctttgttctc cggatctact tcatgagcga
     6481 tcttcgttgc gatggcactt gcaaccaact catgatgtgc cgcttgatat ttgatttgtt
     6541 cttcattttc tccttcttca aaatacagcc ctgcgcccat gaatggtgca tgaaggatca
     6601 tattgatctc attgaatgtc aaccaatatt tgacaagtcc tttatagcga ttgaagatga
     6661 ctcggcacag attttcataa aaaccaacga gttctctgga acgccacgca ccatattctt
     6721 tgatcaaatg catcggacaa tcaaaatgtg taatcgtcac aagcggctcg atcccgtact
     6781 tttgacattc tttaaagaca tcctcataaa atttcaaccc agattcattt ggctcttttt
     6841 catcgcccat tggaaaaata cgactccaag caatggacat ccgataagtc ttgaacccca
     6901 tttctgcaaa taaagcaata tcttccttat aatgatgata catatcgatc gcaatttttg
     6961 ctggataaaa atgattttca tcaaattcaa acattttctt ttttccagta atgacaggaa
     7021 aacggtcttc tccgattggc acaacatcta cgttcgctaa cccacgtccg ccttcatcat
     7081 aaccgccctc gcattgattg gctgctgtag ctccgcccca taaaaaatct tttctgaatc
     7141 ccatcatact tcctccatta catgtgtatt gcttgataat tctcttgcca gttcatcttg
     7201 gacttcgatt ccttctgctt ttaaccggct gattgtttcc ttgaattgcg gtaaatactg
     7261 ctgatgtgca ataaacaact catccatgat ccgttttgct gtctttcctg atcgtataag
     7321 cggattgatc gtaaacgctt gcaaagctgt tccataatca ccagtcacgg ctgcttcgat
     7381 cgtcagcaat tccatattct tcattacttg caaccagcct ctttcagcag caggaaggga
     7441 accaaacgct acatttcgtg cgccttgtgc gccaacatag gcagtgactt ctactacaca
     7501 atctgccggc agatcaggaa cagctccatc attctttgta gataccacga tctgtgtttc
     7561 tttatttcca tagatcgaag caatcgtttc acaggcagca tctgaataat aagcaccacc
     7621 tcgtttttgc aattgttcag gtttatgatc caattctgga tctttgtata attcaaacag
     7681 ctctgcttct gtttctttca cttgctgcgc tcttgtacca atcgtttgat attcttctaa
     7741 agcatgttcc agcatttctt cttcacgata gtaatagcgg tggtagccac aagggatcat
     7801 gttcatttgt tttaattgtt ctttgaaaaa cgggatgtca aagatatttt tcggcaatcc
     7861 attgtcttca tcgtataaac gatcaatcaa ttctgccgtg cggtcatttc ctttattatc
     7921 tgctactttg tgccaatgga agtgatttag accggcaaac ttgtagatca gctcttcttt
     7981 tttcttgcca agcattgttg gttctgtcat catcgccatt actggcacat tgcataatcc
     8041 gatcacttta tcccatttgc catatctgat aactgcttct gtcaccatcc cgcttgggtt
     8101 cgcgaaatta atcagccaag catttggaca taaacgcttc atgtcttcaa cgattgccaa
     8161 aaccactgga acggtacgaa aagctttgaa tatcccgcca gcaccatttg tttcttgccc
     8221 aatcatccca taataactag ggatccgctc gtctttgatt cgtgcatcta attgaccgac
     8281 acgaaactga gtcgtaacaa aatccgcatc tttcaatgct tcttcccgat ccagagttgc
     8341 atagattttg acttcatacg gagaagcatc ccacatacgc tgagacatct gactgacgat
     8401 ctcaagcttt tcttttcctt cttctacatc tacgagccag atttctcgta tcggtaattc
     8461 ctcatatctt ttgataaatc cttccatcaa ctcgggggtg taactgctgc ctccaccaat
     8521 cgtagcgatt ttgattcctt ttgccatgtt ctcactcctt tactttttac acttttatta
     8581 tcttttttgt aaacaaaaca aacaatagaa attcgtttct ttccagtaac atttacaaaa
     8641 gt
//
LOCUS       DAZKCH010000097         8494 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000097 DAZKCH010000000
VERSION     DAZKCH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.098"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..149)
                     /locus_tag="ACG84X_002448"
     CDS             complement(<1..149)
                     /locus_tag="ACG84X_002448"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9128269.1"
                     /translation="MENHVLETGMQKITTHASITAKPFFEKRGYKVINEQTVELRGQL
                     FTNFL"
     gene            complement(593..1714)
                     /locus_tag="ACG84X_002449"
     CDS             complement(593..1714)
                     /locus_tag="ACG84X_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HFP9128270.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVMDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYKPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="ACG84X_002450"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="ACG84X_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HFP9128271.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="ACG84X_002451"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="ACG84X_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HFP9128272.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="ACG84X_002452"
     CDS             complement(4304..5215)
                     /locus_tag="ACG84X_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFP9128273.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="ACG84X_002453"
     CDS             complement(5232..6239)
                     /locus_tag="ACG84X_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFP9128274.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="ACG84X_002454"
     CDS             complement(6236..8365)
                     /locus_tag="ACG84X_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFP9128275.1"
                     /translation="MKKKLFRIVGIVFISIVLLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8480)
                     /locus_tag="ACG84X_002455"
     CDS             complement(8370..8480)
                     /locus_tag="ACG84X_002455"
                     /inference="COORDINATES: protein motif:HMM:NF024254.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128276.1"
                     /translation="MMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2600 a         1726 c         1485 g         2683 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtttgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccatca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca ataggacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DAZKCH010000098         8219 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000098 DAZKCH010000000
VERSION     DAZKCH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.099"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            295..564
                     /gene="rpsN"
                     /locus_tag="ACG84X_002456"
     CDS             295..564
                     /gene="rpsN"
                     /locus_tag="ACG84X_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFP9128277.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            579..758
                     /gene="rpmF"
                     /locus_tag="ACG84X_002457"
     CDS             579..758
                     /gene="rpmF"
                     /locus_tag="ACG84X_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFP9128278.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            790..1167
                     /locus_tag="ACG84X_002458"
     CDS             790..1167
                     /locus_tag="ACG84X_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128279.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1188..1337
                     /gene="rpmG"
                     /locus_tag="ACG84X_002459"
     CDS             1188..1337
                     /gene="rpmG"
                     /locus_tag="ACG84X_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFP9128280.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1361..2344
                     /locus_tag="ACG84X_002460"
     CDS             1361..2344
                     /locus_tag="ACG84X_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFP9128281.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2374..2496
                     /locus_tag="ACG84X_002461"
     CDS             2374..2496
                     /locus_tag="ACG84X_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFP9128282.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            2514..4037
                     /locus_tag="ACG84X_002462"
     CDS             2514..4037
                     /locus_tag="ACG84X_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFP9128283.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            4061..4300
                     /locus_tag="ACG84X_002463"
     CDS             4061..4300
                     /locus_tag="ACG84X_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128284.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4493..4954)
                     /locus_tag="ACG84X_002464"
     CDS             complement(4493..4954)
                     /locus_tag="ACG84X_002464"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9128285.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5149..5367)
                     /locus_tag="ACG84X_002465"
     CDS             complement(5149..5367)
                     /locus_tag="ACG84X_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128286.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            5485..7101
                     /locus_tag="ACG84X_002466"
     CDS             5485..7101
                     /locus_tag="ACG84X_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFP9128287.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(7342..>8219)
                     /locus_tag="ACG84X_002467"
     CDS             complement(7342..>8219)
                     /locus_tag="ACG84X_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9128288.1"
                     /translation="SLSQLLPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENR
                     QLNPLRDYFLRYPIKVREQVRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRA
                     FTNHRIQVMKTFKKGDRRSKHLKKYWKLLQKNAWELKGQHRYWRPSFRDHLTEAEIVD
                     RLLSYDDSLKRGYEVYQDFLSVIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYQT
                     EIKRALRVPYSNGPIECLNNHIKVLKRIAYGYRNFQNYRERIFLYRGKYFKKTKNTTQ
                     LTKARTTTRLDKIAV"
BASE COUNT         2807 a         1271 c         1647 g         2494 t
ORIGIN      
        1 ttcatattgc cgttttaagt agaggaaaag ctacttaaaa cggtatttgt gtttgattgg
       61 actaataaaa gtgaattctt atttttcaga gcctaaactg catattcttt taaatgattt
      121 gattatctct atgtaccgat aaattcgttt tcaaatagtt atctattcat atgagtttta
      181 tttcatgtta tttattgttg acaagagcaa ctcttgttgg taaagtatca gtgtcaaaac
      241 gtaacgatta cgatttgagg tgtctaaatc aaaataaaag gagtataaag gtatatggca
      301 aaaaagtcga aaattgctaa agcaaagaaa caaatggcga tgattgaaaa gtatgcagat
      361 aaacgtcagg aattaaaagc cgcaggagat cgcaccgctc tcgctaaatt gccaagagat
      421 tcaaatccga atcgtctgag gcttcgtgat cagacggatg gtcgtccaag agggtatatg
      481 cgaaagttcg gtatgtcccg tattaagttt agagaacttg cccatcaagg gttgattcct
      541 ggagtaaaaa aagcaagttg gtaaaaggag gaaatatcat ggcagtacca gcaagaaaaa
      601 catctaaggc gaagaaacgg ttaagaagaa ctcatcaaac tgtagtaaaa ccagaaattt
      661 catttgacga agcgaatggt gattatagac gtagccatca tgtatcttta aaagggtact
      721 ataatggaaa gaaagtaatt aaaggagctt caaaatagtt taatatataa cttttaggag
      781 ggaatcaaaa tggaaattat ttacccacct ttagttgaag aaggattaaa gtattatctt
      841 gaaacgaccc agcaatcgct agataaatgc actttttatc gttcgatggt agagagagga
      901 attattactg aaacgggttt accgacccaa caggcaattg aaaatggatt agtcaaagat
      961 tactatgagg accaaggctt atcatttgat gattttttaa gaatctatcc aatttttgaa
     1021 gagtatgacg aggagttatt tcaatgtatc gatggttatt gggagatacc tgttgatatg
     1081 aaagaaaatt tagtttcaca attggaatct ggcgagttaa cttttgaaga tgcacaacaa
     1141 attcaagcat atcttgaaga tcgataagta ttgaaggagg aagatttatg cgtcaaaata
     1201 ttattttgga atgtgtcgaa actggagaac gtctgtatct caccagcaaa aataaacgga
     1261 ataaccctga acggttagaa ttaaaaaagt attcgccaaa attgcgcaga cgggcaattt
     1321 ttaaagaagt gaaatagcta agtggtaaaa aggtgacaaa atgggcatac cagttacaat
     1381 cgtttctggg tttttagggg ctggaaaaac aacgctaatc aatcaagcct tgcaagtctc
     1441 accctacccc agggaagaaa ttattataat tgaaaatgag tttggtgaag ttgggattga
     1501 tcacaaatta ttagttcata gcgaggaacg ggtgttacaa ctaaataatg gatgtatgtg
     1561 ttgcagtctt cgcagtgatt tattagcaat attgatttct ttactggaaa caatagaaga
     1621 acatcaacaa ccaatttcac aaatcatcat tgaaactaca ggtatagcag atccccaacc
     1681 aatcattcaa acacttttaa cagcgcctca actaagagga agagtatata tcgatagttt
     1741 attgactgtt attgatagtg acagttttga acttattgaa agagaaccac aagcccttaa
     1801 gcaacttgtc atggcagatc gcatttttgt gtctagaaaa caaaacttga atttatctgc
     1861 actaaaaaaa ttacagagag aaatcaaaag tattaaccct ttatccgata ttcgaatgtt
     1921 cacacatagt gaaacgattc aaaaaaagga tttttataat ttgaaaaaat ttaatcatcc
     1981 cttagttttt gaaagtgatt catcagaaaa tcactataat ggcaaatact atcatcaaca
     2041 ccatcaagta catgagttta aatcaattct cttaacttca gatcaagaca taaaaaaaga
     2101 ttttttactc caatggattg actggctgat tttaaccaac caagggagcc tgtatcgttt
     2161 taaaggattg attgctttac aagagcagga ttttatagtt gccatgcaag aggtaaacga
     2221 acaggttaat tttcaataca ccactcgaca aaaagaccaa accactatta ttctaatcgg
     2281 aaaaatgttg gatgaagaaa ggatcaaaca gagttttgat aaattactgg cggaaagcaa
     2341 ataatgataa gtagtgattg ggggtaattt ctaatggaga aaacggatat atctagtgca
     2401 tatcgacgac ttaaaagccc gaatattaaa actagaaaaa gggcattaaa aattatcaaa
     2461 gaacataaac gaaataaaat gaagaaatta gcataattaa ggaaggaaaa agaatgaaga
     2521 aaatcagtgt aggacttatt gggatagcag ctctaggatt attgggagct tgctccagca
     2581 ctaatgatgc aaaagtatcg aatgataaag atggaaaatt agaaattgta acaacattct
     2641 atccaatgta tgatttcacc aaaaacatcg tcggcgatga agcgaacgtg gatttaatgg
     2701 ttccagcggg atcagaacct catgactatg agccctcagc taaggatatg gcaaaagctc
     2761 atgatgctga tgtttttgta tatcataacg aaaacatgga atcatgggta ccaaaagcta
     2821 aagaaagttg gaagaaagct gggcctaatg tagtagaagg aacaaaagac atgattttat
     2881 tgccaggtag tgaagaagaa gatcatgatc acggagaaga agatcaccat catgaactag
     2941 atcctcatac gtgggtttca cccaaaatgg caattaagga agtttcaaat atcaaggatc
     3001 agttagttaa attgtatccg aaaaaagcaa aagtatttga gacaaatgct gaaaagtatt
     3061 tgactaaact gaaacggttg gatgctgact ataccactag tcttaaagaa gcgaaacaaa
     3121 aaagttttgt gacgcaacac gcagcctttg gatatttagc tttggattat ggattgaaac
     3181 aagttcctat tgctggacta agtcctgaag aagagccatc ttctggtcga ttagctgaat
     3241 taaaagagta tgttaaaaaa aataagatca attatattta ctttgaaaag aatgctaatg
     3301 ataaaattgc aaaaactttg gccaacgaag ctgggataaa attggaagta ctgaatcctc
     3361 ttgaaagtct tacaaaagaa caaatggata atggtgaaga ttatgtttca gtaatggaag
     3421 acaatctaaa agcgttagaa aaaacaacta tggttgctgg tgaagaggta gttccagaaa
     3481 aagaagcgaa ggatgaaaag acagttgcta atgggtactt taaagatgcc gatgtgaagg
     3541 atcgcgaatt gagtgattat acaggcgaat ggcaatctgt ttatccgttg ttaaaagatg
     3601 gaattttgga tgaagttttc gattacaaag caaaaatcaa taaagacatg acagctgccg
     3661 agtacaaaga ttattatact actggctata agacagatat tgatactatc aacattaaag
     3721 acaacaccat tgattttgta gtcaacggtg aacatcatca atacacatac aaatatgttg
     3781 gatacaaaat tttgaattat gaaaaaggaa accgtggtgt tcgttttaat tttgaaactg
     3841 atgatgcagg tgctggtcgt tttaaatata ttcaatttag tgatcatgga attgcaccaa
     3901 gtaaggcaga gcatttccat attttctttg gtggagaaag tcaagaaaaa ctctataatg
     3961 aattgcataa ttggcctact ttctatccag cttcattgtc taaacatgaa attgctcaag
     4021 aaatgatggc tcattaaaat tcaatttttg gaggaaatac atggtaagaa aagtattatt
     4081 gtctatggat tccaagaata ttgatgctta tcggcgttat cgatttgcaa agcaaatgag
     4141 attaaatggg agtacattag ctgatattgc tgcaacttta catgttagta ttgacacagt
     4201 tcatagagta ttaaaacggg atcctgattg ttgttttatc aaggtcaata ctggaagaag
     4261 tagacgttta gcaaaacggc ataatagctt ggccaattaa ttgataatac cagagtagat
     4321 catttttccc ttatttggat ttgatctgct ttttattatg tcttgaattg tcaaatcaag
     4381 cgcaacactt tatcaaagaa gacttcataa ggtgttctcc aatctaaaca ctttctaggt
     4441 ctgttattca gtttttcaat catctgattt atcgttgagt tatctaccgt agctatctct
     4501 ttcgattttg gcaagtattc tcgaatgagt ctattcgtat tttaatttgt tcattgttgc
     4561 caagggcatg aggatctgga aaataaaagg gcatattatt caatgcttct gtaactgcga
     4621 aatgattgga gaattctttt cctctatctg gagtgatcgt tttgaccgcc tcatttggaa
     4681 tactgcttaa aagttcaatc attttctcgc tcacataagc ggctttcttt ctggggacct
     4741 tctttcctgc taaaaggaag catgattttc tgtctgtcaa agtcactaaa caagtaccac
     4801 cagttttgcc agctacaata tcggctttcc aatgaccaaa atcacttcta tcatctgcgg
     4861 attttggacg gccatggatc gaatgagtaa ggcaaatctt tccacgagac tcgacatgat
     4921 tttttgtatg tcttgttttt cctcgatggt gcaatgaacg gatcaggcct ttattgccgt
     4981 gtgagagggg ttctgtatcg aaaagatcat tgcaaattgc acgttagatc gtgataaaac
     5041 taattgaaaa gtccatatgt tcatgcttca aacgattcga gatttcctct ggcgaccact
     5101 gaaaatcgac aaataaatga cgaacaattg accaaactca cggatcattt agaatgtgat
     5161 aacgtccgca tttttttctt cgataagcat aatttttttc cgctttggaa ggtgaatagt
     5221 ttttttcttg tttcttctca gttcatgtaa aatagtaaac gggctatgct gaatgtcgtt
     5281 gccaattata ctaatagaaa atccttcttc gtgaagcaga aagattcttt ctcgttcgag
     5341 tatagtaaga tgacgatact ggctcataat tattttcctt ctaggagtgt tctcgacaaa
     5401 cttatactag ttggatatcg attatgactc atttttatgt gttgcactta aagtgtaaat
     5461 tcaaggtata gaaagaggtt ccctatgaaa aaaataccta ttacaatctt aactggctat
     5521 cttggttcag gaaaaacgat acttctaaat catattctgt acggtgatca cggaaaggaa
     5581 attgctgtca ttgtaaatga cataggggaa gtaaatgttg atggggtatt agtcgacaag
     5641 aaaggtttta aaagaactgg agaaaaactt gtttcgatgc cgaatggatg catttgttgt
     5701 acattacgcg aagatttgat tgttgaacta gatcaattag tgcaattttc tgacttgaat
     5761 caaattgtta ttgaagcttc aggaatcagc aaaccaattc caattattca agcaattata
     5821 ttagctaaaa accctttaga cattgatttg acccaacgat tagagattgg tgccattatt
     5881 atagtagtgg atgtaaaacg tttttgggat aatttcgaaa cgggtgaaaa gattcaggaa
     5941 agaaaagctg aaggtaatgt agttgaagaa gaacaggata ttcgtggctt gttaattgat
     6001 caattcgagt gttgtaacat attactttta aataatagtg acttagtgtc aaccaagacg
     6061 atttacaaaa ttaacggtct aattgctaag ttacagtcca atgccaaaat aattaggaca
     6121 attaaaggtg aagtagactt atcgaaaatt ctaaatacaa atctttttaa tatagatgag
     6181 acttcctatt cagtgggctg gttcaaagag ttagagcttg gctatcaaaa tcatattcct
     6241 gaaacagaag aatatggtat ctcaagtttt atctatcgaa atcggttact ccttgacgca
     6301 caaaaatttg cccatcttac ggataaaaat tttcctggca atattacaag agcaaaaggg
     6361 tttctttggt ttgcccaaca tagtgatttt tcgacgatct ttgaaacatc gggtagctat
     6421 aaaagtattg aatcattaaa ttattgggta gctagtttac ctaaaattga gtgtcaaatg
     6481 attatacaaa aaaatcccga attgaaggaa gcctggcatc cgttgtttgg tgaacgcatt
     6541 aataaactag tttttattgg tatgaagatg gatcaacaat gtattaagga acaacttgag
     6601 ggttgtttaa ctgattctct taatgcagat aatttccgaa aaatttcacc atttccatgg
     6661 aaaaagtcta atatgtttag ccagatatcg ttaatgaaat ttttaagaaa agctggtgtc
     6721 aagataggcg atgtcataat tattggcatt ttgattatta cctcttttat tcccttattt
     6781 gtattctcta tagaaaagga gaatgaaaca actgaagatg ctatcaaata tgccatcgtt
     6841 cgaattgatg gcaaggaaat ggatcgcttc gatttggata agatcaatca taaactcgtg
     6901 aattatcatc ctgcgaaggg acaatataat attgttgaga ttaaagatgg aagaattcga
     6961 gttaaagaag ataatagtcc tgatcaaatc gcggttagaa ctggatggat ctcaaaaccc
     7021 ggtcaaacga gtatttgttt accccataag ttagttatta gtattgagaa aaaagaaagc
     7081 acagattact acatttacta atctggaaat agatgaggag gtttttaata agaaaaagat
     7141 attattatta ataatagcag gggctttatt aagtgtgtta agcgcttgtg gacaagaaaa
     7201 agaagcggtg acaacaggca caagtatctt taacgggacc tgcaatggtt tagttaacag
     7261 tcggttagat tacttatttt ggctcttcgt caatgagtgt tggtgaagaa attcaataga
     7321 ataatcgaga tactcacacg gctagacagc tatcttgtct agccgtgttg ttgttctggc
     7381 tttagtcagt tgggtagtat tcttagtttt cttaaaatat tttcctcgat ataaaaagat
     7441 tcgttctcgg tagttttgaa agtttctata gccataggca attcgtttta gtactttgat
     7501 atggttattc aaacattcta tagggccgtt ggaataggga acgcgcaacg ctcgtttgat
     7561 ttctgtttgg tatttcttga aggtcgtgaa cactggttgg tagtgctctg gcaactcctt
     7621 gtagtcttct tttaggagcg cgacgaattc aggaacatct tgtcttctga taacggaaag
     7681 aaaatcctgg tagacttcgt agcctcgctt taaggaatca tcataagata atagccgatc
     7741 gactatctct gcttctgtca gatgatctcg aaatgacgga cgccagtagc gatgctgacc
     7801 tttcaattcc cacgcattct tttgaagtag tttccagtat ttctttaagt gcttcgaccg
     7861 acgatcccct tttttaaagg tcttcattac ttgaattcgg tggttggtaa aagcccgacc
     7921 aatgtgttgg ctaatatgaa agcgatcggc gacgattcgg gcattcggaa aacactcttt
     7981 caccaatgtg cgatagggtg tatagaaatc tgaaaccact agacgcactt gttcacggac
     8041 ttttataggg tagcgcaaga aatagtcgcg taaaggattg agttgccgat tttccacaat
     8101 atcaatcagt tgatgggtct tgccgtccat catgacaaag ctcatggctc ccgagacatt
     8161 tttcactgat ttgaattcat cgaaacacac cacttctggt aacagctggc tcaaagaaa
//
LOCUS       DAZKCH010000099         8203 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000099 DAZKCH010000000
VERSION     DAZKCH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8203
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.100"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            476..1339
                     /locus_tag="ACG84X_002468"
     CDS             476..1339
                     /locus_tag="ACG84X_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFP9128289.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="ACG84X_002469"
     CDS             complement(1468..3090)
                     /locus_tag="ACG84X_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFP9128290.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="ACG84X_002470"
     CDS             3339..3860
                     /locus_tag="ACG84X_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFP9128291.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG84X_002471"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG84X_002471"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFP9128292.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="ACG84X_002472"
     CDS             5941..6759
                     /locus_tag="ACG84X_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFP9128293.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="ACG84X_002473"
     CDS             complement(6862..7059)
                     /locus_tag="ACG84X_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128294.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="ACG84X_002474"
     CDS             7228..7806
                     /locus_tag="ACG84X_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFP9128295.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="ACG84X_002475"
     CDS             7901..8038
                     /locus_tag="ACG84X_002475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128296.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2455 a         1480 c         1619 g         2649 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ata
//
LOCUS       DAZKCH010000100         8099 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000100 DAZKCH010000000
VERSION     DAZKCH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.101"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(133..589)
                     /locus_tag="ACG84X_002476"
                     /pseudo
     CDS             complement(133..589)
                     /locus_tag="ACG84X_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            754..3116
                     /locus_tag="ACG84X_002477"
                     /pseudo
     CDS             754..3116
                     /locus_tag="ACG84X_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
     gene            3484..4407
                     /gene="truB"
                     /locus_tag="ACG84X_002478"
     CDS             3484..4407
                     /gene="truB"
                     /locus_tag="ACG84X_002478"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFP9128297.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4411..5352
                     /gene="ribF"
                     /locus_tag="ACG84X_002479"
     CDS             4411..5352
                     /gene="ribF"
                     /locus_tag="ACG84X_002479"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFP9128298.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5704..6489
                     /locus_tag="ACG84X_002480"
     CDS             5704..6489
                     /locus_tag="ACG84X_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9128299.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6502..7353
                     /locus_tag="ACG84X_002481"
     CDS             6502..7353
                     /locus_tag="ACG84X_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFP9128300.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7477..7929)
                     /locus_tag="ACG84X_002482"
     CDS             complement(7477..7929)
                     /locus_tag="ACG84X_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128301.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
BASE COUNT         2724 a         1377 c         1713 g         2285 t
ORIGIN      
        1 aaatcagggg ttgcgggatt tttttgtttt cattaagacg tattacctaa gagttccatg
       61 actttagtct tgcggcgtgt cagctaacca aaaaagagaa aaagaaaagt aaaaaattcg
      121 actttctttt ttctagtagt atataaattt ttgcatatag ataaagatca agataccgat
      181 aacggaagct agattgtaat ctattttagt gacagtcagg tatagccaag taactagaag
      241 atcagtggaa cctgcaccat aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa
      301 aatcacgttg aagttattga tatttccgat tacgccgctt cgatttggtc acgatccaaa
      361 ttttggataa tccctgtaga aattagcata gtagctggga taccaattca catattgaca
      421 aagataacag agacttttac ataaaacgga tcaatcagga aaggaattgc tcgatccagc
      481 cccagttttc cagcaatgtg ttaactggcc cagcgtcatt cagcaaatta tgcatgatga
      541 ggagcgaaat gaactgcgga acagccattg tgataacgac aagttttttg gatcaatgta
      601 aaaaacgtca gcgaaaggaa aaatttcgtg gttttttata cctgttcatt tggctagata
      661 taaaatccaa acaaatgaac agaagtgctt attaggtttc aattgggagt atctgcgcta
      721 gaataagagt aataatgaaa aggagtgtta tgtatggatt attctagtaa agaatacttt
      781 gataaaatga cggcttggtg gcgtgctgct aattatcttt ctgttgggca actttatctt
      841 aaagataacc ccttactgag acgtacactg aaacccgaag atgtcaaaaa acatccaatc
      901 ggtcattggg gaacgattcc tggccaaaat tttatttatg tccatttgaa ccgagtcatc
      961 aataaatatg atttgaacat gttttatatt gaagggccag gacacggcgg acaagtcatg
     1021 gtatcgaatg cttatttaga tggaagttac acagagatct atccagaagt aacggaagat
     1081 gagacaggaa tgcaaaaatt attcaaacga ttttcatttc ctggaggcat tgcttctcat
     1141 gcagcaccag aaacaccagg ttctatccat gaaggcggag agcttggata ctctctttca
     1201 catgcagtcg gagctgtatt agacaatcct gaagtaatct ctgctgtcgt gattggtgat
     1261 ggtgaagcag aaaccggtcc tttagctgga agctggttct caaatgtctt tatcaatcca
     1321 gtgatagatg gagctgtttt accgatcctt catttaaatg gtgcaaaaat agccaaccca
     1381 acgatcttgg cacgtaaatc agatggagaa ttagcaaatt actttaacgg acttggctgg
     1441 gaacctttct ttattgaagg aaatgattca gaaaaattaa atcctgttat ggctgaaaaa
     1501 atggatcaag caatcgagaa aattaaatcc atccaaaaag aagctcgcct gaagacagca
     1561 acagatgtcg tgatgccaaa atggccagta ttgatcgtac gcacaccaaa aggatggacc
     1621 ggtccaaaag aatgggacgg ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg
     1681 attcctgtag atcaagaaca tatggatcat gcagatgctt tactccgttg gctgaaatcc
     1741 tatgaaccag aaaaattatt tgatgcacaa ggacgtattt tagaagaaat cagagaaatc
     1801 gcgcctactg gtgaccaaag aatggcaaaa aatcctatca ccaatggtgg aatcgatcca
     1861 agaccgctta ttatgccaga ttggaaaaaa tatactttgc aatttgaaaa accaggctcc
     1921 gttaaagcag aagatatgac cgaacttggt aaattcgttc gcgagatcat tgagaaaaat
     1981 ccagaaaatt tccgtatatt tggaccagat gaaacaaaat caaaccgatt gaatcaagtt
     2041 ttcaaaacga caaatcgcca atggatggaa aaaatcgaac cagaaaatga tgaatggctt
     2101 tcgccatctg gtcgcgtcat cgacagtcaa ttatcggaac accaagatga agggttctta
     2161 gaagggtacg ttctgactgg acggcatggt tttttgcaag ttacgaatca ttcttgcgag
     2221 tggttgactc tatgttgact cagcacttca aatggatgcg gaaatcacat gacctttctt
     2281 ggcgaaatga ttatccttcg ctaaatctca ttgcaagctc aacagtcttc cagcaagatc
     2341 acaatggata tagccaccaa gatccaggaa tattgacaca tttggcagaa aagaaggcgg
     2401 agttcatccg tgaatatctg cctgcggatg caaatacatt gctcgcagtc atggataaag
     2461 cattccgctc gtcagaaaaa atcaatttga tcatctcttc caaacatccg cgtgctcaat
     2521 tttactcagc agaagaagca gccgtcttag tgaatgaagg cttgaaaatc attgattggg
     2581 cttcgacagc aaaagaggag gaacctgaat tggtcattgc tgctgcagga acggaatcta
     2641 acttagaagc attagcagct gtaactttgc tgctggaaga attcccaaaa ctaaaaattc
     2701 ggttcatcaa tgtcgtagat ttattgaaat tacgtcatcc aagtcaagat ccgcgtgggt
     2761 tgagcgatga agaatttgat caatatttta caaaagacaa accgatctta tttgctttcc
     2821 acggttatga aacattggtc cgcacgattt tctttgatcg tcataaccat catttaatga
     2881 ttcatggcta caaagaaaat ggagatatca cgacaccatt tgacatgcgt gtagtaaatg
     2941 aacttgatcg ttatcatttg gcaaaagacg cagctttaaa aatcaaagga agtcaagcag
     3001 aagattttgc gaaaaaaatg gatcagaaat tacaagaaca tcaaaactat attcgtgaaa
     3061 atggtattga tctgccagaa gtattggatt ggaaatggaa aaatcttgac caataaaatg
     3121 ataaaatcga tcccgcaaaa tagaattttt tacattgatt aagaaactga aaaaataaat
     3181 aaaaaaaacg gaaaaaagac tggaagaatg gccagtcttt tttttcgttt ttgggaagtg
     3241 aaaaccaaac tatttacctg taagccaccc ataaatccaa tcaaatggtg caaagaaaaa
     3301 atcttccatt ctattccctc ctttaaaaaa gcataacatg atttctattt acgtgagcat
     3361 gaattttgtt acgtttttat tgccgaaaaa taaaaaccgt tcattatgat gtcaaattcg
     3421 tcagtaattg atgcaatgtg ttataataat tcagttaaat caaaaatgaa atggagaaaa
     3481 gacatggacg ggttattacc tttatggaaa gaacgcggaa tgacaagtca tgattgcgta
     3541 ttcaaattaa gaaaaatctt acatacgaaa aaaatcggac atgggggtac gcttgaccca
     3601 gacgtagacg gtgtgttgcc catttgtatt ggaaaagcca caaaagttat cgaatatttg
     3661 acagattctg ggaaaatcta tgtaggcgag ataactctag gtttcagtac aacgacggaa
     3721 gatcgatccg gagaacgggt agaaacaaaa ccagtagata tgtctttatc tgaaaaaaaa
     3781 atagatgaag tgatggcttc atttattggt gagatcaccc agataccacc aatgtactca
     3841 gcggtaaaag tcaacggtaa gcggttatat gaatatgccc gcaataatga aacagtggag
     3901 cgtcctgtta gaaaggctca gatttaccgt tttatccgga caagtgaatt gacaagagac
     3961 gaagtgacag gaaccatttc ttggcgcttc gaagtagaat gcgggaaagg aacctatgtc
     4021 cgcacattag ctgtagatac aggcaagaaa cttggttacc ctgcgcacat gtctgatctg
     4081 acccgaacag caagtgccgg tatgtcccag aaggatgctc tgacattaga agaagtagct
     4141 caagctgtga aaaatgggac aatcgatgat tgtttgctgc caatagaaaa aggagtggaa
     4201 cggttcaaac gagtagatat tactgatgaa gtatggcaga aagtaaaaaa cggtatgaga
     4261 cttgattata ctgtatttgc gctcccagaa atgccgtcag aagaaattgc tttgttttat
     4321 aaaggaaaag ttgtcagtat ttatcagcca aacccgaaag aaaaaaacaa attaaaacct
     4381 agtaaagtat tgagaaatga ggaataacga atgaatatca tcaagatcag acatccttac
     4441 caatcagaac aaattccaga agacgatgtc gttttagtgc tgggattttt cgacggcgtg
     4501 catatcggac accagaaagt cataaagaca ggtatggaaa ttgcacaaaa agaaggattg
     4561 aaattagcat tgatgacttt caatcagcat ccatctattg tctttaaaaa gatcgatcct
     4621 agcagcgtga aatatttgac tagccttaag caaaaagaag aaaaaatggc cgctttgggt
     4681 atagattatt tatatgaagt tgattttact tcttcttttg ctcatttagc accgcaggaa
     4741 tttgttgatc aatacatcgt agggttacat gcaaaatatg ctgtttccgg ttttgattat
     4801 acgtatggac caaaagacat tgcagatgtc gctcattttc ctgaatatgc caaaggaaga
     4861 ttcaaaatcg tcacagtttc taaagaagaa gaacaaggtg aaaaaatcag ctctacccgt
     4921 attcgtggat tactagacag cggacaagta aaagaagcag caaaactatt aggttgcaca
     4981 tatgaggtag aaggggtagt tgtccatggc gatgcacgag gcagactact aggattccct
     5041 acagcaaatg tcaaagtaaa gagcacggtt catttgccta aagaaggtgt ttatgtgtcg
     5101 gaaataaaaa ttggggaaac atggtatcca gccatgggtt caattggaca taatgataca
     5161 ttcggtgaag gacgggagct gactgtagag ttgtatattt tggactttaa tcaagatatc
     5221 tatggtgaac atgtcgcggt acgctggaat caatttttaa gagatcaagt gaaattttct
     5281 agtgtagagg aattgattga acaactcaag gaggatgaac aagcaacagc tgaatatttt
     5341 tctcagcaat aaaacattat gcataaaatc tcttgtttat gtataactag caattacaat
     5401 aaaatgggtg ataaataagc ccaggaaagg ggctgtgaca aaagtcttgt cacagccttt
     5461 ttttccaaat aaatggtttt tcagaagtag cttcttcgga aataagccga aatttcttga
     5521 agctgaccac ttctgtcaca acctctttct ttatagaaat aaaaggacac tagcaattca
     5581 tgaaaacgat tgctagagcg tatcatttgc tttagactat atatcttggt gtacactcac
     5641 tttaaggcgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa aggagtgggt
     5701 actatgtaca aggaattaga aaacaaagtc gcagtagtaa ctggtggctc aaaggggatt
     5761 ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt caactataac
     5821 tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg cggaaaagca
     5881 gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact tgatacggct
     5941 ttagaaaatt ttgggacact ggacgtttgg gttaataatg ctgggatgga aaatcagcat
     6001 ccaacccatg aacttagcct tgaagattgg gaaagagtgt taaaagtcaa tttgactggc
     6061 gtttttatcg gaacgaaagc ggctttaaat tactttacag agaataataa aaaaggaaat
     6121 atcatcaata tgtcttctgt tcatgaacag atcccatggc caacgtttgc tcattacgct
     6181 gcttcaaaag gcggggtaaa attatttacc gaaacggtag caatggagta tgcaccgaag
     6241 ggaatcagaa tcaatagtat aggccctggt gctatccgta cacctattaa tgcggcaaaa
     6301 tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg acgcgtaggt
     6361 gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc cagttatgtt
     6421 acaggtatta cactatttgc agatggtggg atgactttat atccttcttt ccaaggtgga
     6481 aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc agttggctgg
     6541 gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga gatattagga
     6601 actggtattg gagcggtgct tgtcggctta ctcgttcaat tattcgcttc tccagctggt
     6661 atttcagtga ctacattttt gattagttta ctttctggtg cattttgggt tattggacaa
     6721 acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc aatttcgact
     6781 gcattacagt tagtcggaac ctcgttgatt ggtgtcttcg cttttggaga atggtctgga
     6841 agtatgggga aaatcattgg agcagcagca atcattcttc ttgtatttgg ttctgcttta
     6901 acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat tagtctatta
     6961 gcatcaacaa gtattggtta ttgggtatac agtgcattgc ctaaactagt tgatgcaagc
     7021 ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt gatttatgtg
     7081 attttccgta aaccaaccgc attttctgaa gacaagagtt ggaaagcaac gatcgttgga
     7141 gccatcttta gtgtgtcagc attggcttat attttttcag caaatgaaaa tggggttgct
     7201 actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg tatgtacatc
     7261 ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt attgctgatc
     7321 gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa tttcatttat
     7381 taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc gctagaattt
     7441 ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaaggg aaatatctgt
     7501 ctggatcaat aatttttcat tgatccattg actaaagttt acgacataat tgaagttacc
     7561 accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa gacggtcttt
     7621 tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggaatt gattgattgc
     7681 tgtaaaatca cgatattgaa ggttgaaacg catcgtgatt ggtgcattta gcatgaatcg
     7741 ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa aaagattacg
     7801 ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt catgaagata
     7861 atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta ctgagtaaaa
     7921 atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga tatttgctta
     7981 atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca agtcagaaaa
     8041 ttctaacttt tatttctcta aagaaattcg ttctctccta aagtgatatt atatttaaa
//
LOCUS       DAZKCH010000101         8055 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000101 DAZKCH010000000
VERSION     DAZKCH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.103"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..394)
                     /gene="pssD"
                     /locus_tag="ACG84X_002483"
     CDS             complement(<1..394)
                     /gene="pssD"
                     /locus_tag="ACG84X_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssD/Cps14F family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HFP9128302.1"
                     /translation="MNKKICFAASSGGHYEQLMMLKPLMEKYESFVITEQTEYSAESK
                     GEKTYYMRQVNRKEKFFLCTILINLFKSIIIYIKEKPDLVICTGVLAMIPICLITKMM
                     GKKLIYIESFAKVTSPTQTGKLMYHFADQ"
     gene            complement(408..1658)
                     /locus_tag="ACG84X_002484"
     CDS             complement(408..1658)
                     /locus_tag="ACG84X_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFP9128303.1"
                     /translation="MKKKYNIAVAGTGYVGLSIATLLAQHHQVTAVDIIPEKIELINK
                     RKSPIQDEYIEKYLTEKELDLTATLDARSAYKSADFVVIATPTNYDSRTQHFDTSAVE
                     SVIEVVMDVNPDTIMVIKSTIPVGYTESVRETTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMTDERLLNAAHVFATLLQKSAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPGNLIEAIVESNRTRKDFIADRVLQMAGYYNYAEYNQYDVNRENPVLIGIYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPALKDGETFFGSKVINDLEQFKAMCDSII
                     ANRYDTCLDDIKEKVYTRDIFQRD"
     gene            complement(2036..3487)
                     /locus_tag="ACG84X_002485"
     CDS             complement(2036..3487)
                     /locus_tag="ACG84X_002485"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFP9128304.1"
                     /translation="MYKKSSRGWVKHIDFIILDLLCIQLAFYLSYVLRQVDWNPYVIP
                     MYQNMAVFIELADLLVIFMFEAYRGVLKRGYYIEFASSVKQAIMLVLLGSLYLISVQG
                     GNDYSRVVLFLMGGLYVVITYITRLLWKHYLKHKMKNEGNKSLIIVTSSSIAEVVIRN
                     VKEHNYKMYKINGVIIIDKSMIGEDVEGVTVVSDSKNAADYLCQGWVDEVFIILNKST
                     SCMKEFIERCSEMGLTVHLNLAKVSDSALGKQSIGRIGEYTVLTTSINVMTTQQAFIK
                     RTIDILAGIVGCIATGIIFIFIAPLIYINSPGPIFFAQERIGQNGKPFKMYKFRSMYM
                     DAEERKVELMKENKMSNNLMFKMEFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FFNVLTGKMSLIGFRPCLKSEYEEYDYHHRARIAIKPGITGMWQVSGRSDITDFEEVA
                     KLDTEYIKNWSMGLDFKILFKTVKTVLQRGGSM"
     gene            complement(3808..4572)
                     /locus_tag="ACG84X_002486"
     CDS             complement(3808..4572)
                     /locus_tag="ACG84X_002486"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFP9128305.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNVHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(4600..5298)
                     /locus_tag="ACG84X_002487"
     CDS             complement(4600..5298)
                     /locus_tag="ACG84X_002487"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFP9128306.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILSEARQLFDV
                     VIFDMPPVVAVTDAQIMSLKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(5310..6089)
                     /locus_tag="ACG84X_002488"
     CDS             complement(5310..6089)
                     /locus_tag="ACG84X_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFP9128307.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(6105..7049)
                     /locus_tag="ACG84X_002489"
     CDS             complement(6105..7049)
                     /locus_tag="ACG84X_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFP9128308.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(7095..7874)
                     /locus_tag="ACG84X_002490"
     CDS             complement(7095..7874)
                     /locus_tag="ACG84X_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128309.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQYHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKIRAAYATKAQTVAQQMGYSNISY"
BASE COUNT         2272 a         1685 c         1309 g         2789 t
ORIGIN      
        1 attgatctgc aaaatgatac atcaattttc ctgtctgagt agggctggtt acttttgcaa
       61 acgattcaat ataaatcagt ttttttccca tcatttttgt tattaagcag atagggatca
      121 tagctaaaac acctgtacaa atcacgagat ccggtttttc ctttatatat ataataattg
      181 atttgaataa attaataagt atagtacaca aaaaaaactt ttcttttcta tttacttgtc
      241 tcatgtagta cgttttttcg ccttttgact cagctgaata ttctgtctgt tctgttataa
      301 caaaactctc atacttctcc atcagtggtt ttaacatcat taactgttca taatgccccc
      361 cagaggaagc cgcaaaacat atctttttgt tcatattaac ctctctatca gtcacgctga
      421 aaaatatctc tagtgtaaac tttttcttta atatcatcca agcaggtatc atatcgattg
      481 gcaataatag aatcacacat cgccttaaac tgctctaaat cgttgataac cttacttccg
      541 aaaaaagtct ctccatcttt cagtgcaggc tcataaatca ccacagtcgc acctttagct
      601 tttacgcgct tcataactcc ctggattgaa ctctgacgaa aattatcact gttgctcttc
      661 atggtcagcc ggtatatacc gattaaaact ggattttccc tgttgacatc atactgatta
      721 tattcagcgt agttgtaata gcccgccatc tgaagaacac gatctgcgat gaaatcctta
      781 cgggtacgat tagattcaac gatagcctca atcaaatttc caggaacatc tgcatagttt
      841 gccaacaact gcttggtatc ttttggcaag caataacctc catatccaaa ggatggattg
      901 ttgtagtgag ttccaatacg aggatcgaga caaacaccat tgattatctg ctgagtattc
      961 agccccttca tttcagcata agtgtctaat tcattgaaat agctgactcg cagtgctaaa
     1021 taggtatttg caaacagctt tactgcttcg gcttcagtga atcccataaa aagagtatcc
     1081 acgttctcct taattgcact tttctgcaga agtgttgcaa aaacatgagc agcatttaac
     1141 aagcgctcat cagtcatatc agtaccaaca ataatacgag atggatacag attatcatat
     1201 aaagccttgc tctcgcgcag aaactctgga ctaaaaataa tgttcttact ccccgttgtc
     1261 tcacggactg attcagtgta gccaacagga attgtagact tgatgaccat gatggtatca
     1321 ggattcacgt ccatcacaac ctcaataact gactcaacag cagaagtatc gaaatgctga
     1381 gtacgactgt catagttagt cggtgtagca ataacaacga aatctgcgga tttataagcg
     1441 ctccttgcat ccaaagtagc agttaagtca agttcttttt ctgtaagata cttttcaata
     1501 tattcatcct gaattggaga cttccgttta ttaatcagtt caatcttttc agggataatg
     1561 tctaccgcgg ttacctggtg atgctgcgcc aatagtgtgg cgatactcaa accaacataa
     1621 ccggtgccgg ctactgcgat gttgtacttt ttcttcacaa tatctcctct ttcctctctt
     1681 aagtatggag aatgttactc ctacggctat tcatcatgtc aaaataacac agcttagaat
     1741 gttgataaaa taattttcca gaatgtgata aaatctcttt catttataaa ccacacatct
     1801 aattttatct attctccaca agacatgtag agtattcttt aataacaaga tacgacctta
     1861 ctaaatactt caaaaaatta tcatatttaa ttcataaata taaatcttca ttttaaatgt
     1921 atgcccaaaa atttatctgt aatgcgtcat caaaatctag attccaaatc tttatcaatt
     1981 tttatccact cattctacca ctttagtaat attttctatt tataacactt tcgtcctaca
     2041 ttgatccccc cctctgaagt acagttttta ctgtcttaaa taaaatttta aaatctaacc
     2101 ccatactcca attttttata tattccgtgt caagttttgc tacttcttca aaatcagtaa
     2161 tatcacttct accacttacc tgccacattc cagtaattcc tggcttaata gcaattcttg
     2221 cacgatgatg ataatcatat tcttcatact ctgatttaag gcatggtcga aatcctataa
     2281 ggctcatctt tcctgttaga acgttgaaaa attgagggaa ttcatctaaa gacgtggatc
     2341 taataaattg accgattcct gtcttttttg ttccatctgg aagtatttta tttccgataa
     2401 ttcttggatc aaactccatc ttaaacataa gattattgct catcttattt tctttcatta
     2461 attctacttt tctttcttct gcatccatat acatacttct aaacttatac atcttgaacg
     2521 gtttaccatt ctgacctata cgttcttgtg caaagaaaat tgggcctggt gaattaatat
     2581 aaataagtgg agcaataaag ataaaaataa ttcccgttgc aatacatcca acaatacctg
     2641 caagaatatc aattgttcgt tttataaatg cctgttgagt tgtcataaca ttgatacttg
     2701 ttgtaagtac tgtatattct cctatacgac caatagattg ttttcccaaa gcactatctg
     2761 atacttttgc aagattcaaa tgtacagtaa ggcccatttc agagcatcgt tcaataaatt
     2821 ctttcataca cgaagtactt ttattcaaaa taataaagac ttcatctacc catccctgac
     2881 ataagtaatc cgctgcattt ttggaatcag aaacaactgt cactccctca acatcttcac
     2941 caatcatgct tttatctatg ataatgacac catttatttt atacatttta tagttatgct
     3001 ctttcacatt acgaataact acttcagcaa tactactaga tgtaactata ataagtgatt
     3061 tgttcccctc atttttcatt ttatgtttca agtaatgttt ccataagagg cgagttatat
     3121 atgtaattac aacgtataaa cctcccatca agaaaagaac gactctagaa taatcatttc
     3181 caccctgaac actaatgaga tacaaacttc ctaacagcac caacataatc gcttgcttta
     3241 cagaagaagc aaattctata tagtaccctc tttttaatac acctctatat gcttcaaaca
     3301 tgaaaataac taaaagatct gccagttcaa tgaagactgc catgttttga tacattggaa
     3361 tcacataagg attccaatct acctggcgta agacatacga tagataaaaa gcaagctgga
     3421 tacacaataa atctaaaata ataaaatcaa tatgtttaac ccatcccctt gaacttttct
     3481 tgtacattcc tttttactcc cctcttttta ataaaataaa ttgtattact tgttttctct
     3541 cctaaatatc tttctgaagg attattgact cgacaaattg gcttgtggat attcttatat
     3601 atagaacatc cgtaagccaa cttaaaactc cttaacaaaa tttttttact catattgtag
     3661 atcaaaacaa gtatccaaga aatcatattt tatttctttt ttctgcttac tcaacaacag
     3721 ctaaaagaaa aatcatcata aacaaattca actaagccaa cgatcccctt gtgaaatcaa
     3781 gttttttctt gatttacgaa taaagagcta aaataaacca aacttcttct tttttacctc
     3841 ttcatagact ggataactga tttcatcccc gttgatcaga tcctttgcga cttgtttcat
     3901 ctgtactact ttttccttac caaagtcctt tgcaatctgc tcatagcact cttttaagta
     3961 aaaggtgcgc ttagagaccc catgggcatc agaagcagcc atctgcacga gattatgttt
     4021 gaccatcgtt ttggctgttt tctggatgtc tttgccaaat accccaacat aacttggcgc
     4081 agtgagttgg gccaaacatc ccatatctag gaacggaagc aaatgatttg ggtcttcgcg
     4141 aaaatgcacg ttgcgttctg gatggacgat tactggtgtc tttcctagtt ctaacaactc
     4201 aaaaaaaagc cgttctgcat ataacggcac ttccagtgtc ggaaattcga tcagaagata
     4261 tgtatcatct aaatctgtaa ataatatttc atctcggtgg atgtcttcga tgagcgttcc
     4321 ggtaatacgt acttcttgtc cttccaataa cgtcaaaggc aactgtcttt tctctaattc
     4381 ggcttgtaac gaagcgacta gagaaatgac ttgtgatttt tcattgctgt attttccatt
     4441 attgtggtgt ggtgtgcata aaatatgcgt gatgccttgc tgaatcgctt tttcagccat
     4501 tgcaatactt gcttctaagt tttctgcccc gtcatcgatt cctggtagga tatggcaatg
     4561 tagatcgatc atttctcttg tctcctctct tcttattcct taatttccgt agtaataacc
     4621 agcatctttg ctatgttctg ctccgttgta cacaacacct aagactcgtg cttgtaccat
     4681 ctccagcagt tcttttgctt tagtcaagga ttctttacgt gacatatttt cacgtacgac
     4741 caataaagtg ccatccgttt ttaaagacat gatctgtgca tctgttacgg ctactactgg
     4801 tggcatatcg aatatcacca cgtcaaataa ctgtcttgct tcggatagga tctgatccat
     4861 tcttggcgag cttaacaatt ctgatgggtt gggtggctta ggtccactag gcaaaatcga
     4921 caagttctcg actggcgttc gttggatcac atctgctaca cttcctgatg aactaagtgc
     4981 tgtacttaat ccactggcat tgttcagctg gaatgtctta tagacgacgg gtttacgtaa
     5041 atctgcatcg actagtagaa ctcgttgacc tgatttagca aaaacgactg caatgtttgc
     5101 tgcagtggtg gatttccctt ctccaggacc tgatgaagtc acgacaatcg ttttgatttg
     5161 ctgaccagct gcggaggcaa actggatatt cgtccggatc gtacgatatt gttcggcgat
     5221 tggtgaagat gggtttgtta atgtgatcaa actgactgca tgagtttgtg ctgctttttg
     5281 tttctgtgtt cgtgccattt ttcttcctcc tagactcttg agcggcttct gcgtgatggg
     5341 gctgttttat cgtttgtagc ttttggtcgt gcaggagctg ttcctttttt acggatacca
     5401 gcgttcaatt ctttcgctga catttctgga actgttccta agattgggaa tcctaatgta
     5461 tctgtcacat atttttcatc tttcactgtc cgatcgagta attccaataa gaatgccaga
     5521 cctacaccta ccatcattcc taacattaag ccagtcatta aattcaattt attatttggc
     5581 gaaacaggtg tcgtattggc aactgcacct gaaatgatcg agattttatc aacattcatc
     5641 acatcttttg cgttctcttg gaaaacttgt gaagttgtgt tagcgatctg ttgagcagcc
     5701 actgcattcg tacttattgc ctgaatcgag aacatttgtg aattttctgc ctgattaact
     5761 gagatggcat ctttgatttg ttcagcagtc attttcacat tgtcttctgt ttctaaacga
     5821 tctttgactt cattgagcac taaatcactg acgatcatat ctttatacgt attgatcatt
     5881 tgcaggttcg tattgacatc attgacattt gcagtgtctg attgtggcag tgtcacgatc
     5941 aattgtgctt gtgaactgta ttttggtgtc aagatgaaaa atgttacgat tcctgagatg
     6001 gccaagccag caaacattga gatgatgatt attaccaagt gtttgcgtaa tgtttcaaaa
     6061 atttctttca agctgattgt ctcttccatt ttttctccac tttcctattt attctctaga
     6121 ttcatttgat cttttaattc ttttttcaca cgatcaagtt cttgatcact gactttttga
     6181 taggagatat tatcttgcat gaagccttct ccttgcagct gatcttgctt aatcgtacca
     6241 aatgcctccc gataatctaa agcaattttt ttcatttcat caaagttcat gtctgttttc
     6301 atattcgact ctagagcatt caaaacggat tgatagttgc tgacaccgtt tagactcaat
     6361 acttttttcg ctacgccttc tacgatcttt ctttggcgcc cttgtctacc gtaatcacca
     6421 tttgggtctt cataacgcat acgagaataa gataatgcct gatccccgtt caatgtaatt
     6481 ttaccgattg gaaagtcata gccatcttgt gagaaagtga ggtcattatt gacttcgata
     6541 ccaccaactg catcaacgag ttcctttagt cctttcatat tgatagagac atagtgatcg
     6601 attgggatgt ctacatattt ttgtacggta tccatcgcca tggcagctcc gccgaatgcg
     6661 taagcgtggt tgatcttgtc ttttgtgtca cgacctacga tgtcgacata cgtatctcga
     6721 ggaatgctga cgatcgttgt ctgtttgtct tcaggactga ctgtggcaac catcatcgta
     6781 tctgatcttc cttgatcgac ccgacctaaa tctccagtat caatccccat caatagaaca
     6841 gagaaagatt cttgtttgtc cagatcaact ggtttcgttc gttctccttg ggttcgttcc
     6901 actgattcgt aagttttctc aatagaatgt gagagatcca gatataattt tgctcctact
     6961 cctacaattg ctaatactaa tacgataaga actgctaaaa taatcaaaaa tatttttttc
     7021 cctcttgatt ttcttcttcg tcttgccata gtttcctccg tttgctaacc ttgcttgaat
     7081 caacgtttta actgtcaata gcttatattg ctatagccca tttgctgagc aacagtttgt
     7141 gcttttgttg cgtatgcggc tcttattttt tcattccgga tctgctctat ttgactgagc
     7201 gccgtcaaat attgatcgta agtagcggta gctgttactt gaccgtcttt cagcatcgta
     7261 tcgaatagct gatctagttg cgtgacttgt gcaatttggg tatcagcgaa tcctagatat
     7321 tgcataacga ctgttttcca agcactatcc ttaaaaaagc tcatattttc acgtacatgg
     7381 gcgacatctg cacttgccaa cttttctttg atgatgacat catccacagc ttgctgccag
     7441 tttgatacgt ttttagtaaa taatttattg acagccgtct ggatcttcag ttttgattct
     7501 gcatcctcta actgcgttaa gactgctttc ttttcttctt ggatcgcagc agcttcttta
     7561 ggtaattctg attccttgat gtcataatca tctgccgaaa gtttgataga agatagttta
     7621 tgtgacaaat ttgaaactgt ttcttctgtt atttcaggat ttaggaaaat tttttctttt
     7681 gtactgtaca gcttatctac ttcttttgat aaagaggtca cggtgtcttt ttgattggtg
     7741 atggcagatt ctgcgtaatt gatccgttga tgatattgcc gctgattatt gagatggtat
     7801 ccaaacaagc aaatcacaat agcgcctgtg cctaccgcca cagtagccaa taacttgacg
     7861 aacggctttt ccatagattc actcctaaat attgatgata gataagtaaa gatgtgattc
     7921 attcacatca gaatgagcgc tttttatttt aaaagcataa ttaaactaat atattcatag
     7981 aaatatttat aaacaggttt tccctatata atcataccac atacagtttt tttgactagg
     8041 gaaattccta attta
//
LOCUS       DAZKCH010000102         7985 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000102 DAZKCH010000000
VERSION     DAZKCH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.104"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            110..811
                     /locus_tag="ACG84X_002491"
     CDS             110..811
                     /locus_tag="ACG84X_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFP9128310.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1420..2436)
                     /gene="tsaD"
                     /locus_tag="ACG84X_002492"
     CDS             complement(1420..2436)
                     /gene="tsaD"
                     /locus_tag="ACG84X_002492"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFP9128311.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2433..2897)
                     /gene="rimI"
                     /locus_tag="ACG84X_002493"
     CDS             complement(2433..2897)
                     /gene="rimI"
                     /locus_tag="ACG84X_002493"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFP9128312.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2904..3446)
                     /gene="rimI"
                     /locus_tag="ACG84X_002494"
     CDS             complement(2904..3446)
                     /gene="rimI"
                     /locus_tag="ACG84X_002494"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFP9128313.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3430..4152)
                     /gene="tsaB"
                     /locus_tag="ACG84X_002495"
     CDS             complement(3430..4152)
                     /gene="tsaB"
                     /locus_tag="ACG84X_002495"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFP9128314.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4343..5323)
                     /locus_tag="ACG84X_002496"
     CDS             complement(4343..5323)
                     /locus_tag="ACG84X_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9128315.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5347..6831)
                     /gene="galT"
                     /locus_tag="ACG84X_002497"
     CDS             complement(5347..6831)
                     /gene="galT"
                     /locus_tag="ACG84X_002497"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFP9128316.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6843..7832)
                     /gene="galE"
                     /locus_tag="ACG84X_002498"
     CDS             complement(6843..7832)
                     /gene="galE"
                     /locus_tag="ACG84X_002498"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFP9128317.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT         2254 a         1705 c         1409 g         2617 t
ORIGIN      
        1 tatttgtaaa gtattaaaac ttgtttctaa tgttggtatg ttaaaacttt acaaattctt
       61 taaaaaaagt gacaataaat atagtgaaca ataaggagag gactttttaa tgcgtgttaa
      121 taaaatcgat tttcactttt caaaactcag atatcaacct gattttgaac atttctcgga
      181 tgaagagttc caacagatca aggaacatac tgttcttcgt tcttataaaa aaggacagat
      241 ccttttcgac gatggtgatc ccagacaacg gttgtatatc ttgaccaaag gactcgttcg
      301 tttagaacgt tatgatgaaa gtgcaactta ttactactat gactatgtga atacaaataa
      361 cctttttcct atgtcaggaa tgtttggaga agagacctac acttatacag ctcaagcgat
      421 gactgatatt gaaacattct accttcctgt ttcctactat gaaaaattag cacgaaaaaa
      481 tcccgaacag ttgatctata tgatacaaaa aatttctaaa gtagttgaaa tacatgaatt
      541 gcgtatccaa atcggattga cctctagcgc ctttgaccgg gtaaaacaaa atttattcat
      601 tttgaaagaa gaattgggcg taccaacaaa agatggtcat atcaccattc cttatccgat
      661 caccttaaaa gaattagcag tgaatagcgg cacgacacgt gaaactgctg gacaagtaat
      721 caaacaacta cgtgattccg ggctgttaga ttatgacaaa aagcgtttta ctttctgtaa
      781 gacagctact actccagcta tgagagaata acgcgaacaa aaataagcag tgaccctgat
      841 aaatatcagg gtcactgctt attttcctcc ctaaaacttc tgaaagatcc ggcagtttta
      901 gatcactgga caagactcaa agattttcta tgtgtgtttc agttatgtaa tattcactgt
      961 ttgcaaaaaa tactgttaga ttaactagat gaagcgtctt gtcctcatcc gatctagatt
     1021 attcgatatt cctcgacaat aaacgattac tcagtgaggg caatcagagg aacggataat
     1081 gataaataag ctgtaaaaaa tagcaaaata acaataatga ttaaaagtat gtaaaaaata
     1141 gggctttgac aaaaacgtgt cacagcccta tttcgattaa acggtgtgta cctgtcaact
     1201 cttcggtcac aagtcataat gttcataaac atgaggagct gttttttgaa attgttcctt
     1261 gtgaatcaga gttaaacgac aggcttacga actcttgatt aaacggcgtt caaaagcttg
     1321 catacgcggt aataagaaca gccaggtcaa aaacatgaga agccgttttt cctgggctgt
     1381 tcttattact tgatgcaggg cagctttttc acaacctctt tattcagata aaaccaagct
     1441 tggatcagca ttcaactgat agctagcaaa atttcttttt tgcatttcca catgtgctgc
     1501 tgctccaatc attgcagcat tatctccaca aagtcgaaga gggggaatca ctagttctac
     1561 ctcagggagt ttagttgcca aagcatcctg caatccttca cgcaaccctt gattggccgc
     1621 tacacctcca gctataatca gttgcttgac tggataattt tgacaagctc gaagtgtttt
     1681 agtaatcaat acatcgatca cacttgcttg aaagctagct gctaaatcat ttttgtctag
     1741 atcttctcca cgctgttgtg cattatgcac caaattgata aatgcacttt ttaatccgct
     1801 aaaactgaaa tcataattat cttcatggat catcgctcgc ggaaaatggt aattatcttt
     1861 tccctgatga gctagctgat cgatttcttt tccgcttggg taagaaagac ctaatactct
     1921 tccaactttg tcataagctt ctcctgctgc gtcatctctt gtctccccaa tgatttcata
     1981 tgatccatct tcttgcatat agactaattc tgtatgtcct ccgctaacaa gaagtgccat
     2041 caatggaaac tggaatggtt taaccagacg ggctgcatag atatgccctg ccatatggtt
     2101 tacaggaata agcggcaatt ggtgtgccca agcaaaagcc ttagctgcag aaataccaat
     2161 cagcaacgag ccgacaagtc ctggtccata agtgacagcg actgccgata aatcttctgc
     2221 cgacacacca gcttctacca gtgcatcttc caagcataag gtgatttgtt ctacgtgatg
     2281 gcggctagct acttcaggta ctacgccacc aaaacgttta tgactgttta tttgagaagc
     2341 aacgatgtta gataagatct ctgttccatt tctaacgacc gctacactcg tttcatcaca
     2401 acttgattca atcgccagaa tcaattcttc attcatttca tcgtctccgt ttttaacttt
     2461 ctgctcataa tgatcgcatc ttccgtcgga ttgcgataat atgatttccg tttacctaat
     2521 atacgaaact tttctgattc ataaagtttt cttgctgctt cattagatag acgtacttct
     2581 aaaaaaacat gcagcgaatc ttttatttgt tccgtaatca gtaattgtaa caaatgccgt
     2641 gcatgccctt ttccttgttc tgaaactgca acagcaatat ttgtgatctc gacttcatct
     2701 attactttcg agtatccaat aaagccacag atctggttat cttcagctaa aagcagataa
     2761 tcagagtgag gctgttggat gtctgccaaa aactgcattt tcgtccaagg tgaaccatgt
     2821 ggataagcat tttcgctaat catccatacg cattctgcca agtacgcttc atcaaaatct
     2881 ttttttctgc aaatcaacta atctcactca ttttctaaaa gttttatcat atccaacgca
     2941 tcttcttttg tttcagtgta atatcttttt ttgatcgttg ttgcttgaaa ccccaatttc
     3001 cgataaagtc tttgtgcatc ttgattactc atacgcactt ctaatgacat cgtctcacag
     3061 cgattcatta tagcaaagtt ctcgatttcg tcaataagca gcgaaccgat tcgtttacgc
     3121 tgatatgccg gtcgaacggc aatattcgtg atatggcaat ctaaaccgaa cgctcttgaa
     3181 ccgataaaac caatcattct tccattatca aagataccta gatatagatg aggaagcggt
     3241 gacttcaatt ctgatataaa ggcacttttt gtccatggca attcgccatt atagacttct
     3301 cgttcgacat ccagcagctc tttgatatct tctgtagtca attctcttag tacgtaacga
     3361 cgatcgattt gttcgactgt tttttctgta taaatcattt tatcttgaaa aaagcttctg
     3421 gcatacgctc taaatttttt caacataact ttcgtctcca ggtgtgtgcg tctccaacca
     3481 tttttcttct gcttctactc gttttaaata gcgaggaaga aaagcttgtt tctctgcaac
     3541 tggttcaact aaagcaccta attgagccac agttacacca cttggaatat cccatgctgg
     3601 aactgtatta atcatcgcac taggcaatat ttcctttatt tcagagaaga atttgtgaca
     3661 atcactcccg acgaaataaa tagcttcatt cagcttttgt agttgtgtga acaaatcaga
     3721 agcagaaata tgtacatctt caagtacagt ttctaatcta ttttctttcc agcggtatgc
     3781 cccagcgtat acattttttc ttcgagcatc aaacatgggc acaataatat tatccacacc
     3841 gatgcaatta gccgcgatgg ttttcagact agatactcct actagctctt tatctaatgt
     3901 ataagcaatc gtttttgctg tcgttacacc tatacgaagc cctgtataag aaccgggacc
     3961 atcagaaacc gcgattcggt caatgtcttt tggacttatt tgaagatctg caaacaattg
     4021 gtcgattgca ggcatcagtg ttacactgtg gttgcgtttg atatttgttt gtatttgtcc
     4081 aagaatttgt tcgtcttcta ccacaccgat cgccaaagtt tggtttgcag tatctattcc
     4141 taatgtaatc atatatttga tcctttctgc tatgacattc tcgccttcca ttgtagcata
     4201 cttttttatt ctgaggatga aaataccaaa ggcaaaacta gtacaataat acatgattat
     4261 ctgctggcgg gcaaattttg ccccttcctg aaacacaaaa aagctgcggt atcactccat
     4321 tttcccacag cttttccatc ttttatttcg ttgattctcg aataatcaac tctgtttcca
     4381 caataatctt tcttgaaacc ggtgctttgg aattacttaa ttgaagaatc gtctccactg
     4441 ctagctctcc catccattcg gtataaactt ttacagtaga aagcgagggc gttacatatt
     4501 tcgctacact gacatcattg aagcccatca cagaaatatc ttctggtacc actaaacctt
     4561 tttcttgaat cgctttcagt gcgccaatcg ctaatgcatc attagctgca aaaagcgcat
     4621 caggaacatg cggattcgtt tttaaatact gcttcactgc ttgatatcct gactcgacag
     4681 aaaaatctgc ttcgataatt ggaccttcgt cgtagccttt ttctgccaaa acttgttgaa
     4741 atgccataat tctgggatct tttagccgct gatggttttt cttcgtatat tctgttccag
     4801 caagcatagc gatatgttgc gctttatggg agacaaagtg ttcaatgact ttttgaacac
     4861 ttgacttaaa gtcgacaact agagagtcga ttccttgaga agtgccgtca gaatctacca
     4921 aaagcaaggc attttgggat cctttcattt ctaataactg agcttcgtcg aattttccta
     4981 gtgcgatcgt tccatctgcc ggaagatcac taatggaatc ccacgtttct ttcaataaag
     5041 taacgtttgc ttcttctgcc tttttttcga ttcctaggcg aatagataaa taataaagat
     5101 cttcaagctc ttccgtatcg tcgtaccact ggatcaggcg aagcgtttgc ttagtatttg
     5161 ctgcattttt acgatgtttc gtataattta agcgttctgc tgcttcaaaa attttttgct
     5221 ttgtggctaa gccaacggaa agatcaggat catagttgag aactcttgaa acagtagcag
     5281 gagaaactcc tgccaactgc gcaatgtctt taattgttgc catttgtctc tcctcctttt
     5341 ttacgtttat aaaatcgcag taaatcgttc aaacgctgcc tgtccttttt catctcgctt
     5401 gaatactcca gcgtcttcca gtacacgtgc aaaaacctga cctacagatt tttgtacgac
     5461 atcggtgacc gtatctttcg tcaaatcagg atgttctttt tttaattgtt ctgcccacgg
     5521 acgatgatat tcagccatct ggttttcttc tcctaataag aaatgctcta cttctactag
     5581 ttctggtttc aaacgaggtg gtaaaacagc aagccccatt acttcgatca acccaatgtt
     5641 ctcctttttg atatgttgga catctttatg tggatgaaaa atcccatcag gatgttcttc
     5701 tgaaacattg ttgtctcgaa ggacaaggtc caactcaaag taattgtccc ttcttcgtgc
     5761 aattggcgta atcgtatggt gtggtgtacc atctgctgaa aaagctctga tagatactgt
     5821 ttcatccgaa tatgctttcc atttttccaa tactgagtta gctgcttcaa taagcaagtt
     5881 tttctctgtt gattgcaaac ggatcacaga catcggccat ttcacgactc ctgcgatgac
     5941 ttgcggataa tcttctagtt tgataagttt ttctatcggt gcttttgcca taggaaattc
     6001 atgacgtcct gcctgataat gatcatgaga aagaatcgat cctccaacaa ttggtaagtc
     6061 agcattcgaa ccaacaaagt aatgaggcaa gacttcagta atccgaagca gtctagcaaa
     6121 tgtttccttt gtgattttca tcgggcggtg ttgttctgat aaaatgatcg aatgttcatt
     6181 gtaataagca taaggggaat attggaatcc ccagctttca ccgtctagat tcattcgaat
     6241 aatccggtga ttggtgcggg ctggatagtt caagcgacct ctatatcctt cgttttccat
     6301 gcaaagcatg caggtaggat agtctacttt taccgcctcg cgttctgctg cgatttgttt
     6361 tggatctttt tctggcttag ataaattgat tgtgatttcc agttcaccat actccgactc
     6421 tgccggaaat ttgatgtttt ttgcgatggc tcttgttttg atgtagtcat ttttcttact
     6481 taaattaaag aaatactcag ttgcttcctc tgggcttttc gaatagtgct gtgcaaagaa
     6541 tgcattgacg actgaaggtg gcggtgtgag aaaatccatt aattgcgctt caaaaatctc
     6601 ttgttctgct ggcaattctg aaagaacacc attttctctt gccttagcga caagctgatc
     6661 caataagtct acagattctt ccttaactgg tcttacttca atgctttcta gagcatcttc
     6721 tcctaccatc cctaaaagac gattctgtaa atataagcgg tccatttcca tccatccgcc
     6781 agcttcgatc gcaagtgtgg caaaatcaca aatcgtttga ctgattgaca tatctcattc
     6841 ccctattctt cataaccatt tggatggctg acatgccaat cccatgctgt tttgataatc
     6901 gctttgatat ctgtgtattc aggtttccag cccagaatct ctctcgcttt ttcacttgaa
     6961 gcgactaatc ggctaggatc tccagctctt cttggtgcta tttctgctgg aatttctttt
     7021 cctgtcactt ctctagctgc ttctagcatt tccttgactg agtatccttt gctgctgcct
     7081 aaattgaaga agttgctttc atttccttct ttcaagtatt ccaaagctaa aatatgtgca
     7141 gcaatcaaat cttctacttg aacataatct ctgatacatg ttccatctgg tgtatcataa
     7201 tcgtctccat aaacagccaa ggcttttctt tgaccaagag ctacttgtaa aatgattggg
     7261 acaagatgcg tttctggtgt atgatcttct ccgatagatg catctgcttt tgctccggct
     7321 acattgaagt agcgcaaagc gacatagcgc atgccatatg cttggtcaca ccacttcatc
     7381 attttttcca tcatcaattt actttcacca tacggatttt taggattagc tggtgtatct
     7441 tctgtgattg gagactcttt cggctctcca taagttgctg cagtagaaga gaatacgatt
     7501 ttattcacgt tgaactcgtg catgacttca agtaagattt gcataccgta tacgttgttg
     7561 ttgaaataca tcaatggttt ttcgacagat tctcctacta aagagcttgc agcaaaatgg
     7621 attactcctt caatcggttc cttttcaaat acggaacgta gaaattcttt atcccggatg
     7681 tctccttcat aaaaatgagc atctggatgt actgcttgtt tgtgacctgt gagcaaatta
     7741 tctaccacag ctacttgata ccccttttga actagctggt ctacagcgtg cgaaccgata
     7801 taaccggctc cgcctagtac taaaattgtc ataaaaaaca ctcctttgat tagtaaaatt
     7861 gtgtttgttg attctatata atttaaaaaa cgaagtttac ttttatggtg aaaacaaaca
     7921 aagtaaaatt tcgtaaattc atatggtaaa tttataataa aacatttagt aaacattttc
     7981 aagga
//
LOCUS       DAZKCH010000103         7537 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000103 DAZKCH010000000
VERSION     DAZKCH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.105"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            107..1248
                     /locus_tag="ACG84X_002499"
     CDS             join(107..335,335..1248)
                     /locus_tag="ACG84X_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9128318.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1483..1935
                     /locus_tag="ACG84X_002500"
     CDS             1483..1935
                     /locus_tag="ACG84X_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128319.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1949..2638
                     /locus_tag="ACG84X_002501"
     CDS             1949..2638
                     /locus_tag="ACG84X_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128320.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2763..5114
                     /locus_tag="ACG84X_002502"
     CDS             2763..5114
                     /locus_tag="ACG84X_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFP9128321.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            5194..5589
                     /locus_tag="ACG84X_002503"
     CDS             5194..5589
                     /locus_tag="ACG84X_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128322.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            5914..6531
                     /locus_tag="ACG84X_002504"
     CDS             5914..6531
                     /locus_tag="ACG84X_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9128323.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            6572..6871
                     /locus_tag="ACG84X_002505"
     CDS             6572..6871
                     /locus_tag="ACG84X_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFP9128324.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            6905..7072
                     /locus_tag="ACG84X_002506"
     CDS             6905..7072
                     /locus_tag="ACG84X_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFP9128325.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(7117..>7537)
                     /locus_tag="ACG84X_002507"
     CDS             complement(7117..>7537)
                     /locus_tag="ACG84X_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9128326.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2594 a         1138 c         1502 g         2303 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc gtagaatcta actactaaga aaaggacgtg tccacgatgg caaaagccaa
      121 gaaaaaattt gatgaagact ttaagaagat gatcttagat ttaaaccagt ctggccaatc
      181 ggtcgaagaa ctggcagcgc aatatggtat cgctacacaa acgatttatc gttggaagaa
      241 gcttcataca aagaatgtag caaccggcat gactgaggca gaaatcctag cgatgaaaaa
      301 ggaaatggcc cgcatgcagg aggaaaacac tatcctaaaa aaggctttaa ccatattcgc
      361 tcaaaagtaa aaatgagtga tgtcttcgaa tttattcaat caaatgttca tgatcatgac
      421 gtaaaacaaa tgtgtaccgt tttggaagca ccgaaatcca gctactatga ctggaagaaa
      481 aagaaacctt ccaagcgcca atcagaaaac aaacgcttaa accgcttgat ttcaggaatc
      541 tactttgaaa acaagggtat ctatggtgcg cctaaaattc ataagattct tgttggccgt
      601 ggcgagacct tgtccttaaa gaaagtacaa atactgatga gaaaattagg cttgcgttca
      661 gtcaccctca agaagtacaa gcctggcaaa caagcgaaag ttaaaagtga aggacgtaaa
      721 aacctgttaa accaagattt taccactacg tcgatcaatc aaaaatgggt gacagatatt
      781 acctatattc ataccctaaa agatggctgg acctacctct ccactattca agacctccac
      841 acaaagaaag tcatcggttg gaagtttggc aagcagatga cgaaagaatt ggttatcgaa
      901 acccttgaca atgcgctctt aaaccaaaca ccctccgaga acttgatcat ccactcagat
      961 ttgggttctc agtacactag cgaagcctat gaggcaaagc tgaatgaatt gaacattcgg
     1021 cactccttca gtcgtaaggg ctgtccctac gataatgccg gtatcgaatc gtttcacgcc
     1081 tcactcaaaa aagaagaagt ctatccatca aaagcgtatg aaaactttga agctgcttat
     1141 ttagcgttat ttcaatacat tgaaggattt tacaatcgca agcgaatcca tagtagtatc
     1201 aactatttaa caccaaatca gatggaggag ttggcattgc aagcttagtt cctagctacc
     1261 acttacattt ttttggcgag atttccacag ggtttcaact tcatcgcttc gatcagcggt
     1321 caaacggttt tggtttgacc gctggtcgaa acgatgagat actcacccgc tggaatctcg
     1381 aaaaaattct cacaaatcgt gtccgaggta ttgactcaaa tccaccaatt atcttatcgt
     1441 agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa aacgatacta
     1501 agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa tttagattct
     1561 gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa taaaaaaatg
     1621 agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga atttggtgat
     1681 ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga taaaattgtt
     1741 gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt tagttataaa
     1801 caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc gattaaggat
     1861 ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga aactaattca
     1921 gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt ctgttgggct
     1981 acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag ttatttcaga
     2041 tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata aagtacttgc
     2101 attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg ataatccaga
     2161 tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag tgacagaagc
     2221 aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa ttatgcctcg
     2281 aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag caggaggagg
     2341 aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta tgggtgtaaa
     2401 accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg atggaagagt
     2461 aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa tggcattgta
     2521 tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa tgaatatagg
     2581 tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa atatttaata
     2641 aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg acaaacacta
     2701 aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag caggggattt
     2761 ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac agtaatgtta
     2821 cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc tatggactta
     2881 ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt ggacctacca
     2941 ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta cctaaaaata
     3001 ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt ggcttcgatg
     3061 gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat gcagggttta
     3121 atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta tttgatatga
     3181 gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag caatggttaa
     3241 atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat caaagaaatt
     3301 caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc agtgaagcaa
     3361 cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa ggtaactcgg
     3421 gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt gaagacggta
     3481 cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc cgaaaattta
     3541 tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga ctattgtcta
     3601 gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa ttaactagat
     3661 ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat cttactggta
     3721 ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa ttgaataata
     3781 ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca gcattagctt
     3841 attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca gcaaaaaatc
     3901 taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg ttaggggaag
     3961 aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg tcatatagcg
     4021 ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc aataacgggt
     4081 atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat ttaggttttc
     4141 ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga agtggcaacg
     4201 gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt aatgagttat
     4261 caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt ataaatcaga
     4321 tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg aaccctcatt
     4381 tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt tcttctcctg
     4441 taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact aatagcgagg
     4501 gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg cctcacttaa
     4561 ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt gtttctgact
     4621 ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa ttaggaatac
     4681 aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca tttagtctag
     4741 aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa agaaattctg
     4801 attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct attgatagat
     4861 ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca gtaacaaata
     4921 gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt tcatttttca
     4981 ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat tttattggag
     5041 atgaggggaa agttgcaaat ggattttctg aaaaaattat tcaatttcaa gaaaatagaa
     5101 gtaaacttaa ttaagaatcg tttactattt aaacagtgtc cttttccttt ttaaatatat
     5161 acgataaaat aagtatatga attgtaaaag gacatgatga ttatggaaga aatagaatgg
     5221 aataatctga ctcaaaataa taaaaataat tctggatgtg gaattatctt tatgtttgtt
     5281 atagttttgg gaatagtagt acttttaata actgtcaaga tagtagatta ctttgcgaat
     5341 actcctgaag aacaaataca gagaaaactt cctgagtttg aaagagtacc accttatgat
     5401 ccaagagata attcatttca agtaaaaaaa ttaaaagagt ctccaaatga aatgtggttt
     5461 gaagttacag ttgaatcaag cgacttcaaa gaaaaaaaga aagaatacaa ttatattgta
     5521 aaggcaaaag tatcaaaaag atttattttt aaccctaaat tagaaatata tagtgttgta
     5581 atagaataat agtgttaaaa aaattgtaaa agttaaagaa gtcaaattct gatgtgaaaa
     5641 ataaaatata ccatggaaga cataaaagaa aaactggata actagtttat ttaatggcag
     5701 accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca tgcgggagtg
     5761 taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt tgtttatgta
     5821 tggcataata accacataat acaatttgaa acgtttctga tttaatctga ttgttttgaa
     5881 acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta tatccgggtc
     5941 agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt aggaatccct
     6001 gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc tgaatatcaa
     6061 ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt agatagacta
     6121 ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga aaagcagatt
     6181 gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca actagatggg
     6241 ttagagacgc ttatctctga cttaattctg caattactca gctatatggc cgaagacgag
     6301 cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca aaagggtgta
     6361 aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta ttctgactgg
     6421 aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa acgaaatacc
     6481 ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg atagatataa
     6541 cagctattag acgggaaggg agagtttgaa aatggactta acgaatcaaa gggtcgtttt
     6601 tactggaacg ctgcagcaaa tgacacgaac ccaagccatc ggtttggttc actctttaaa
     6661 cggccattgt caatcaagtg ttacttcaaa aacaaatttc ctggtttgtg gtcagtattc
     6721 taagtcgttg tttgatgatt ctctctatac aaaaaaggaa caaaccgcgc gggacttgat
     6781 tgcgttaggt catgagatta ccattttatc agaagtcgaa ttttatgcgt taattagtca
     6841 acagttgaaa gaatggcaac ggtatttata atcgttagta aaatttacaa ggaggaaaat
     6901 ttttatgaag cgaaaatctt atgatcgttg gggcattgaa ataactagtt ttaatcgaaa
     6961 tattgctttt cacgtggagt gtgactgtgg ggaattagca aaaagtgttt atcaaaaaaa
     7021 ttacttttac tgtcctaaat gccatcgccg atacggggta catggaacat agaaacgaaa
     7081 tagtgcggta gaaaagcgaa tgaatgtagt atatttctac aaatcattcg ctttctttat
     7141 tttataaata gttggtcgag agatcccgtt ttcttttgca atctctgcaa ctggaatgcc
     7201 ttgctttaac atgtccacca cggttttaaa aactaagcgt ttttgcggat ctgttgagtt
     7261 aatagaatac tcgattggtc gtcccttata tcggccggct ttttgagcca ataatactcc
     7321 ttgccgctga cgttcacgaa ttttctcacg ctcgttttgt gcaatataac ttagcagtga
     7381 taaaaacata tcgaacatag cggtatccag gagttcattt ccagtattaa aatctaaaaa
     7441 ctgtgcatct aatattttta acgctacttt tttctgtttc ataaaagcaa ctgtattttt
     7501 tatatcttca taatctcttc ctaaacgatc tagtgat
//
LOCUS       DAZKCH010000104         7338 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000104 DAZKCH010000000
VERSION     DAZKCH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.106"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(332..817)
                     /locus_tag="ACG84X_002508"
     CDS             complement(332..817)
                     /locus_tag="ACG84X_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128327.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(956..1171)
                     /locus_tag="ACG84X_002509"
     CDS             complement(956..1171)
                     /locus_tag="ACG84X_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFP9128328.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            1395..2195
                     /locus_tag="ACG84X_002510"
     CDS             1395..2195
                     /locus_tag="ACG84X_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9128329.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            2214..4082
                     /locus_tag="ACG84X_002511"
     CDS             2214..4082
                     /locus_tag="ACG84X_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFP9128330.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            4075..4566
                     /locus_tag="ACG84X_002512"
     CDS             4075..4566
                     /locus_tag="ACG84X_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFP9128331.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            4554..5108
                     /locus_tag="ACG84X_002513"
     CDS             4554..5108
                     /locus_tag="ACG84X_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFP9128332.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            5126..6121
                     /locus_tag="ACG84X_002514"
     CDS             5126..6121
                     /locus_tag="ACG84X_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFP9128333.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
     gene            complement(6263..>7338)
                     /locus_tag="ACG84X_002515"
     CDS             complement(6263..>7338)
                     /locus_tag="ACG84X_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFP9128334.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT         2503 a         1182 c         1464 g         2189 t
ORIGIN      
        1 atctttctaa tttgaaaaag ggatcattaa aataataaga agaaaatatg tcaaaaggta
       61 aaaaagtaaa ttcttctatc caaatataga aaaattgaat ctagaaaacc gcccgacaat
      121 aaatttcatt aactcagttg accgaaaatg aagtagatac caaaaattta tcaagagagc
      181 aagtagagaa gtgagtatat tcataagaga aatagctgta acgaattatt aggttaatgc
      241 aaatgcttat ttatactccg tataactttc tcagaaaaaa tgataccaat aatgacttgc
      301 tagtactgta aatccgtata atatcatcta atcaaaatgg tgttccattt gcatctgtca
      361 tcgtaatcga tccttcgggt gacactcgat aaaaaccaac gcttccagat cctccttggg
      421 aacggatttg tttgctggaa gctgtgaaca aataatctcg atcaattttt tgataaaagc
      481 taataacaat atcgtcactt tgtaattcgg aacggtgggc aataagaaat agaagtgctt
      541 tgtcagagtt ttctaatgga agagaaggta cagtgctttc ttgcatttca gatgttgaag
      601 aaatgctaaa cgactgaata cttgattggc tatgttgcga atctacatta ccagtagaag
      661 tattagtaat ggaagtagta gaagtacttt tagttgaacc aacctcagtt gttgaaatgg
      721 ctgctgaaga ttctttaaca gaattctttg ttttatatcc acaggcagaa aaaagtatta
      781 cagttcccaa caagcctgcg taaatccctt tatgcatgat agctcctcct aaaatagatt
      841 atctttattc agtatatcac ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct
      901 tcccaataaa gggaaggttc atgaagataa taactttttt aataattata gctttctaat
      961 atctttcatc aacttttcta gtaatcattg ggaaaaattt caagcagtag atcgcacaaa
     1021 tacctacgac gatataaatg atcttcgcaa aaatagttgt tgaaccacca gcaatcatag
     1081 ctactaaatc aagttcgaac aagcctacca acagccagtt caaccctccc acaatcaata
     1141 aagttaatgc aatagcatct aaagttttca ttagaattct cctttcttaa atgataaaac
     1201 aattatatat caaaaagaga aacattgctt atataacgct caggaatttt agcaatctat
     1261 gcaaaaagat gaaaattttt tttgctcttc cattagtaca cattttttag ctgaagctgt
     1321 aaatttcatg tcttaatttt ttttagtgag cttttatact ggatttgtaa gaaaaaagaa
     1381 ggagaggatc acatatgtcg gattggttgg atattgcagg aaaagtagta attgtaactg
     1441 gaggttcctc aggaattgga agaagtatcg tcgaaaattt gttgaagcag aatgcacaag
     1501 tagcgaattt tgatgtaact gaatgccgta tacagcatga aaacctacta tctttaaaag
     1561 tcgatgtgtc ttctaaaacg gacatagaag aagggatata taaagtaatg aaacatttca
     1621 agacgatcga tggtctagtc aataatgcag gaataaatat tccttctctt ctaatagata
     1681 gaaatcatcc aaaaagcaag tatgaattat cagaacaagt ttttgataag atgatcgctg
     1741 tcaatcaaaa aagtgtatat ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg
     1801 gatcaggagt gatcgtgaat ctttcttctg aatcaggatt ggaaggatca gaaggacaga
     1861 gctgttatgc tgctacaaaa gcagcgatga acagttttac tcgttcttgg gcaaaagagt
     1921 taggaaagag gaatgttcgt gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt
     1981 tgagaacaca agaatatgaa gaagctcttt cttatacgag aggtataagc gtcgaacagc
     2041 tgagaaacgg ttacagtcga acaagtacga tccctctagg aaggagtggt aagctgcaag
     2101 aagtggcgga tctagtctgc tattatcttt cagaaagatc aagttatatc actggagtca
     2161 cgactaatat ttcaggaggt aaaacaagag gataaaggat aggggggacg cacgtgacgc
     2221 tagtaaacag atggtaccaa ttattgaaat tactagtcac tcacaagaaa gtttcaatcc
     2281 aggaagtgca aaaagaaatc aaaaccagta atcaaaccat aaaaaaagat attggggagt
     2341 tgaatgaaga aattgccggt attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg
     2401 aaatttatga ttttgatttt tttgatgaga tcatgcaagg aaaattgaaa acagccagtg
     2461 atttcaattc ggcatccaaa agaatcgctt atttactaaa taggctgatc gaaacagagg
     2521 atttcttacg tatggatgat ttgtctgaag aagtcggtgt cagcagagga acagtggtca
     2581 aggatctaaa gacattaaaa gagatgatca atgattttga tgtaaagatt acaggcacac
     2641 caaataaagg actaagaata ataggagatg agctagaatt acgactactt ttattttatt
     2701 ttgtttctcc ctacttttca gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa
     2761 tcaaacattt tcagaagaag acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag
     2821 ttatcggtat ttctttgaat agaatctcta gtaactatct gttgaagaag cccatcaatc
     2881 gttacagtgg gtgttttgaa tatatccaag aattcaatga actgatcaat cagttggaag
     2941 aaatctatga actaactttg agccaatatg aaaaagattt tatcagtttt cctttgaaca
     3001 tcatcaacac aagtataacg atgataagga aagctaactc tgatttgcgc ttatatttcg
     3061 accccatgat gatgcgtatt cgacgattag atctcattga tctggatgag tccttcttat
     3121 atcaagagat gaaacagcac ctctctttat tgataaatcg ggtaattttt cgttatcgat
     3181 tgactgattt attttatggt gagatagaaa aaaagtatcc tttttcttac caaatcgcta
     3241 gcgaatgcat acaagcatta gaagctatct tgcaacataa gatctctaaa gtagagatca
     3301 gctacctaac gttgtatttg gagttagcat ttcgatatca aaaagagcat ttttcctcta
     3361 aaaaagtagc cattgttcat acgacaggaa aaggaacagc attaatgatc caaagacaaa
     3421 tcaaaaggat attggggagg gatatacaaa taacacatgt ttcagaagaa caatatgaaa
     3481 aagtagatct aaacaaatat ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg
     3541 aagagacacc ggtgatccat ttgactaatc tttttgatga ctcttggtta agggcacaat
     3601 ggcaaaaagc aaaaaaaaag cgattagccg ggtttcattc tactgttttt ttctatcaaa
     3661 tatggaaaga aaaaaagacg tatcaagaat atttaaacaa attagtcgct cctttgatca
     3721 gaggctatta tgtggatgaa gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa
     3781 gcacatttgt taacaaagaa tttgcttttc ctcacacaac caaccagcta tctcaacaca
     3841 ttgttttatc agtagggcta ataactgatc aaggtttagc agaaacagga ggaaatggag
     3901 ttattttttt atttgccata cctgaagaaa tgacggctga agttgagaat gaattatttg
     3961 agctatacga tatcctattt gaactcataa aaatgggaat agatgagttt attgaattag
     4021 caccgacaca agaatcattt ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat
     4081 gatatgtatc tattcatagt tttcgcagct tcagcttatg tgctgcaagc agttatcagt
     4141 tggaagcaac taaagcattt caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta
     4201 gcgattggta aacgacctgg gaaaatccgt tcaggcacga ttgttatgct agctatagac
     4261 gatcatgatc aagttttaga agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt
     4321 cattcattac ctgtctatgc gggtgaagat atccattaca tcgatcgtta ccatccctca
     4381 gttcgagcgg aagatcgttt gacacaagca gctttagaaa atgccagaga agtatactta
     4441 cgaatagagg caggaaatga aaaaagtgaa caaccttcat tgccttttat tgctatgctc
     4501 aataattttc ggatatggaa aagtacgatc aaagaaaaaa ggagtgacaa acgatggata
     4561 tcataacaaa atttgctgag ggatttatga ggctgttcca aacaggtgca gaaacattca
     4621 taagctggat gacaggaatc gtaccagttg tcttgatgct gatggttgca atgaatacgc
     4681 tgattgcttt tttaggtgaa gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc
     4741 cgcttactcg ttaccttgtg ttaccgttct tatctgcttt tatgttggga aatcctatgt
     4801 catttacaat ggctcgtttc cttccagaat actacaaacc aagctattat gctgctcaag
     4861 ctcaattttg tcatacgagc aatggtgtat tcccccatat taatcctgga gaattgtttg
     4921 tatggatggg gattgctcaa gggatcgaaa ccttagggct aaattcgatg gagctggcta
     4981 tccgatactt gcttgtggga ctgctgatga actttattgg tggttggata actgatttta
     5041 ctactggatt tgtatgcaga cagcaaggaa tcgttcttag caaaaaagta gagctttcag
     5101 ttgattagag aaaggagagt tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg
     5161 cgggtatgga ggtcctttga ttattaggcc gacaaaagat aaacacaagt tcatctatgt
     5221 cacaggtgga ggtgagaggc caatgatcgt agataaaata gaagaactga caggtatgga
     5281 gtctatcaat gggttcaaaa catcaatacc tgatagtgaa atcgcgcttg caatcgttga
     5341 ctgtggaggg actcttagat gtggaattta tcctaaaaaa gggataccaa ccatcaatat
     5401 cgtttccaca ggaaaaagtg gcccattagc acaatatatc actgaagata tttatgtttc
     5461 agcagtaggg ttagaacaaa tacagccact aatggaaact gatgataaca aagaaacagt
     5521 aaatactgca tctccagata aaaagtacaa atatgatact tctaaaaaga taaccgagca
     5581 aaaagcagag cagcaaaact ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc
     5641 tacattcaat caatcagcaa gagaagcagt agatacgatg atccggacag tgatcccttt
     5701 tatggctttc gtttcccttt tgattggtgt gatacaaggt tctgggatcg gtaatgtatt
     5761 tgctaacatt atggcacctt tagcaggaaa tgcagttgga ttaacaatca ttggctttat
     5821 ttgttcactg ccatttttat ctcctttgct tggtccaggg gcagttatta gccaagtgat
     5881 tggaacattg atcggtgtag agattgggaa aggaaatatt cctccccaat tagcattacc
     5941 ggcactattt gctatcaata ctcaaaatgc atgtgatttt attccagtcg gtctaggttt
     6001 ggaagaagca aaagctgaga cagtagaagt aggtgtacca tcagttcttt attcaagatt
     6061 tcttaacggc atcccacgag ttatcattgc ttgggtagca agttttggat tatatagctg
     6121 agtttagtct aatggtgata agtcaagatg aaatttaaga ttttctttat tgagtaatat
     6181 gttttgaagc gcacgaaact agacccgatc aaaatcaaat ttttttcggg ttgattcaag
     6241 gatttgcgtc aataacggat tgttatttct ctatcacact ccttggtggc gtatagagtt
     6301 ggtgtttacg tagtagcgta tccaccagac gcgtaaattt tcttgcggtt aggacgagtg
     6361 cacgtttgtg ttgatgcttt ggaacctcct tatatttact ttgataaaaa gctttgtatt
     6421 caggaagata attttttaca gagttggcag cttcaactaa gtagtatcta aaatatcgat
     6481 ttccttgttt tgtcagaggt gtattttgcg actgatagtt tccagattgg ttcactttcc
     6541 aacttaatcc agcgtatttt gccaattttg tctgatcttc aaatctttcg atttgaccaa
     6601 tttcagcgat taaaccggca gcatagactt taccaacgcc tggaatactg gttaagcatt
     6661 gatattctgg aatgacaaca attacttgtt cgatggcttt atctaattct ttgatatttt
     6721 tttcaagtgc tcgtatttct cgtacgagaa cacttaaaac aacattaatt gattcttgtg
     6781 caagagcacc taggcggtaa ctcatggtaa ttgcacgttg aattgcttta gcgatttttt
     6841 ctggttgctt gaaacggcct tttccttttt cttgaagtaa atcacagaaa gcttctaaag
     6901 gaagctcagc aagttcatcc aatgtgaaat cttccgtcat gagtgaaatg agggttgcac
     6961 taaaaagact cgtcgattcg tctcgcattt ctcgagcaag cgtattacat ttgtacgtta
     7021 gattttcaag aaaatgttgc tttgtacgaa tcaattgctt aataagttga tagcgagtac
     7081 gtgttaaacg ctgtaaggcc atgtatttct cttctttgat aggggaagtt gtgaatcgtt
     7141 gaatacgcaa gaaatcagcg attcttaatg catcgtttcg atcagtttta ttctcatcaa
     7201 acatgcgact aaattgtttc acccgaaaag gattttcaat cgttacaagt gtgttgagct
     7261 tctttagttt ctcatcttca tgaaaaaaca tggaaggatg gaagctgtac atggacgttg
     7321 actccatgcc aatcacaa
//
LOCUS       DAZKCH010000105         7314 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000105 DAZKCH010000000
VERSION     DAZKCH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.107"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..3660
                     /locus_tag="ACG84X_002516"
     CDS             133..3660
                     /locus_tag="ACG84X_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFP9128335.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..>7314
                     /gene="addA"
                     /locus_tag="ACG84X_002517"
     CDS             3657..>7314
                     /gene="addA"
                     /locus_tag="ACG84X_002517"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFP9128336.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALN"
BASE COUNT         2517 a         1263 c         1536 g         1998 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aata
//
LOCUS       DAZKCH010000106         7231 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000106 DAZKCH010000000
VERSION     DAZKCH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.108"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..335)
                     /locus_tag="ACG84X_002518"
     CDS             complement(<1..335)
                     /locus_tag="ACG84X_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9128337.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVV"
     gene            complement(455..1102)
                     /locus_tag="ACG84X_002519"
     CDS             complement(455..1102)
                     /locus_tag="ACG84X_002519"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HFP9128338.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(1186..2613)
                     /gene="uxaC"
                     /locus_tag="ACG84X_002520"
     CDS             complement(1186..2613)
                     /gene="uxaC"
                     /locus_tag="ACG84X_002520"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFP9128339.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(2687..3766)
                     /gene="uxuA"
                     /locus_tag="ACG84X_002521"
     CDS             complement(2687..3766)
                     /gene="uxuA"
                     /locus_tag="ACG84X_002521"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFP9128340.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(3769..5400)
                     /locus_tag="ACG84X_002522"
     CDS             complement(3769..5400)
                     /locus_tag="ACG84X_002522"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFP9128341.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            5704..6375
                     /locus_tag="ACG84X_002523"
     CDS             5704..6375
                     /locus_tag="ACG84X_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9128342.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(6535..6726)
                     /locus_tag="ACG84X_002524"
                     /pseudo
     CDS             complement(6535..6726)
                     /locus_tag="ACG84X_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
BASE COUNT         2322 a         1425 c          976 g         2508 t
ORIGIN      
        1 actaccttaa cgctcataga agctgaaatc atagaagttt gatacattaa aaaacttgct
       61 aaagcgactg gaccactcat tcttaaaatc cacggtttaa acttaccctg cttagttgct
      121 ttcgatctat caacaatacg ccccatagtt acatcagtaa ctgcatcgat aaatcttgct
      181 actaaaaata atgttccaac ggcagctccg cttatcccca atacttttgt ataaaagatc
      241 attaaaaaag aactagcaaa aatgaaagta aaatcgtttc caaaatctcc aaacatatat
      301 cctattttgt ctcttatacc aaattttctt tccatacaat tctctccctt ctgttgttaa
      361 gcgttttcat tctgatgaaa gtacgtacta tactctgaag cgtaaagagt cagtatttat
      421 tttttacatt tcagagtatt atttgttttt tctcctaata attctttatc tcataaaact
      481 tatctatata tttactagct actcgactta cttcttcaaa atcacctttt tcaacagaag
      541 ccaataaatt cccacctaca ccaactgcaa caactcctac ttcaaaccaa tcttctaagt
      601 tctctatact tactccgcca gtaggcatta tatttacgtg tggtaatgga gcttgatagg
      661 cttttacaat ggatggacca aaagcagaac ctgggaatag tttaatgata tctacgccag
      721 cagtaagtgc ctcctttatc tcagtaattg tcatacaacc tggtaaataa ggaatttgat
      781 ataaattaca aatctcagct gtttgtcgat caaaagatgg actaacgata tattctgccc
      841 cagccataat tgcgatacga gcagtaaacg catctaaaac cgtaccggct ccgattatta
      901 catctttttg atcagcatat tttttagcaa tttctttgat tatttcttca gcattaggaa
      961 ctgtaaaagt tagttcaatc cctttaattc cacccgcaat aattgaattt attgctttaa
     1021 tggcctcatc cttatttttc ccacgtacaa ccgcaatgac tccagccgct tctaacttac
     1081 ttaaaatttc tacttttttc atatctatct ccttccttta tggatacata ctttgtctag
     1141 ctgtactaac ttacaaagaa taaatttaag cttttatttc aagtattatt ttctacttcc
     1201 gatttcaaaa aaattaaaat aattatacgc attacgataa caaatattct ccactatctg
     1261 actaagatac atttcatcat ctggaattcg gcctgcttta acccactcgc ttagtaattg
     1321 acataatact cgacgaaaat actcatggcg aggatagctt agaaaacttc gagaatcagt
     1381 caacatacct gtaaaattcg acaacaaact ttgttgtgcc atcgtagtca actgttgacg
     1441 cattccttca gctgtatcat tgaaccacca agcacatccc aattggattt tttgaatcat
     1501 acccccttgg aagctttgca ttgctgttgc tagtggaagc caatcagttg gatttaatga
     1561 atataaaatt gtttttggta agcacccact cttttcagcg gtatcgaaca atgctacaac
     1621 attttgtgtc aaactagctt gatcccccat cgaatcacca ccgacatcta ctccaatttg
     1681 ttcctttaat atacttgaat tatttcttaa agcatttaaa tgcatttgca tcgtccaacc
     1741 atatcttgta tactcagaca tcaaatgtaa ttgaatacct gtaacaaatt gtgcaatttc
     1801 tgataaatgg aaatccgttt ttcctgctaa agcttttatt aacagattgt cgagtatttt
     1861 ttcatctgct atttcataaa aataagtatt caaaccgtga tctgctaatc gacagccaat
     1921 ttgatgaaaa tgatccactc gttggctcaa tgcttgcttc aacccattaa agtctttgat
     1981 tggtatagcc gctgtttgac taagttttaa aatatagttc gaaaagcctg atgatttgat
     2041 actccagacc ttatctggac ggaaagtagg taataccttg aaagaattat cctgtttaga
     2101 aagctcagta tgataccaca agtcatctgt aggatcatcc gttgtacaga tggctttcac
     2161 atccatcatc tccaacaatt ctttcgggcg ataggaatcc gtttgaattt tttcgttagc
     2221 acgtcgccaa atttctggtg cattcttctc agaaattgtc aaatcaatat caaagtaacg
     2281 ttgtaattcc aaatgagacc attcaaaaat aggattacct ggcgccttct ccactgtttt
     2341 tacaaaagct aaaaattttt cataatcatc acctggacca ctgatcaact cttcttctat
     2401 accattagct cgcatcaatc gccatttata atgatctcca gctcctttat catttaacca
     2461 tacctgagtc aaattcttgt attgcttatt ttctagcaaa tatgctgggt ctaaatgaca
     2521 atgatagtcg ataattggtt ggtgttttgc aaatttatga aaaagtcttt tagctatttc
     2581 attctctaat aaaaagttct tatctaaaaa catatttaaa cactcctttc cttccgttag
     2641 tttttagaag agaaaatttt tcctctaaat aaactccctt atataattat ttactcgccc
     2701 ccttttcaag cgcttcccaa ataccattta aataaactgc acctagagct cggtcatata
     2761 atccataacc aggtctaccg gtttctcccc aaatcatccg accatgatct ggacgaatat
     2821 agccattaaa tccattatcg tacattgttt ttaatatctt atacatatct agagaaccat
     2881 attctgattt atgcggcgct tcgtaaaaat cgagtccatt gtcacttaaa tatttgatat
     2941 tacgaacatg tgcaaaagga atccgatccc gttgacaaaa ttcagataga atttcataga
     3001 catcattatc tggtcgttct gcaatacttc cagtacataa tgtaatacca ttagaaggag
     3061 aatccactac attacacaac caatctaaat cgtcacgatt tttaacaata cgaggtaatc
     3121 cgaaaatgga atatggtgga tcatctgggt gaactgccat tttaatccca acttcttcac
     3181 atgtcgggat aattgctttg agaaaatatg caaagttctc tcgtaatttc tcttcatcaa
     3241 cttctttata ggcttctaat aattgcttaa tttgtgataa ccgatgaggt tcccaacccg
     3301 gcaattcaaa attattagta gaattttcta cttctctaat aatttcctcc ggatcagtag
     3361 ggatattttt tgaaatatag gctaacgtag aagacccatc atctaaacga taatccaaat
     3421 ccgattttac ccaatcaaat actggcataa aattataaca gataacctca atcccaaatt
     3481 ctgccaaatt gcgaatcgtc tgtttataat tctcaatgta ttgatctcgt gttggtaaac
     3541 caattttgat atcatcatga acattaacac tctcaataac tttcaaggta agtccattgg
     3601 cttcgacttc atcttttaaa gatttaattc gttctctcgg ccaaacctct ccggctggta
     3661 tatccattaa tgttccaaca attcctttca ttgctgggat ctgacgaatt tcttgtagtg
     3721 agattttttc ttcatttgcc ccataccatc taaaagtcat ttccatagtt actttcctcc
     3781 aacttctgtt atatatttat tgattgtttt acgaactgct tgaggaccta ctagcatttc
     3841 gcaaaagatt ttttcagttt tctttcctac cccaacttga tataaatcta aaccaaagat
     3901 ttctttattt tctaaaattt cctgtaccgc acaatgaatc tttgaaggat cttgttcacc
     3961 taatttcaat actgataatt tatcctgcaa ctctaccaat aacggatcag gacttggcac
     4021 aaaattttcc ccttgatcat cgactgccag taaataacgt aaccaagcag caatagcgat
     4081 aggaataaat gttagatttt ctgcatttcc gtctttttcg acatactttt taattgtttc
     4141 accatagcga atcgctactt tttgagaagt atctgttgca attcgttgtg gtgtatctgg
     4201 aatataggga ttaggcaaac gtttattaat tacttcatca ataaattgtt ttggatcaat
     4261 aatgcctgga ttttcaacta ctggtaaacc ttctaaataa cctattcctt tgattaaacc
     4321 aaccaaatca tcatcctgca tctctgctga aattgattga tatcctagca gacaacctgt
     4381 tactgccaaa gcagtatgaa gtggattcaa gcttgtcgta accttcatga tgtctgcttt
     4441 atcaaccgtc tctctatctg tcataatcac accagccttt tccaatttag gccggccatt
     4501 tggaaaacta tcttcaataa ctaaataatg aactacctca gtattagtga aagcagcaat
     4561 attggtatgt ttttttgtgt gaatgatatc taaatcctcg agccccatca tcaatagatc
     4621 ttcctttaca ttctctgaag gatttggcgt aattcgatca atcatactcc aaggaaaagt
     4681 cactttttct ttatccttta aataagcaat aaatttttca gaaacatatc cttctttttg
     4741 ccaagcttct gcaatcgtaa aaatactatc ttgaaaacgt tgaccattct gtgagaaatt
     4801 atcagtagaa accatcgcaa tcggcaactc tccagcatta aatctgctat ataacaagga
     4861 tgttacaata ctcatcgtat gttgaggatt gctaggtcca gatttgatat cagctttgac
     4921 taccgaaaag aattgccctt tagaatcttt taaactgtaa cctttttcag taatagtaaa
     4981 cgttgtaaac tgtaatttag gatcttcaaa atatttaacc actctttgat agtccgctat
     5041 attcttcgga ttgcaatata aactatcagc cgttactgcc aaaagtcttt ttttgagttc
     5101 accatctcca ctcataacaa tttccaaaat gtcattgtta tagtcatgat aagctttttc
     5161 cactacttct tcatcaaatg tttcacacac aactactcct gtttctaatt cattttgatc
     5221 tgctaagcat tgagcaattt ctgcatgaaa tcctcgataa agatttcctc caccaaaatg
     5281 aagccatact ggatgttgct ggccttcttg cttaacttct ttgacatcaa aacacggcag
     5341 tagaatctgc atttcattga attcttcgat agaattttgc caatttttaa tcgaaaccat
     5401 aattaacctc ctcaaactga tatgttagtt ttgatacatt ttatatttta aaacccattg
     5461 taaccgttgt caatataaaa agggaataaa cttgcttttt tctaccatat cagaatgatt
     5521 gtatttttta ttcagaaaaa taaaatactc cttctttttg gactgatttt atcgaaactt
     5581 attttttctt tttttcatgt attcttttat ttttataact agtgtattac ttcaaaattt
     5641 gatattatat ggcatgaaca gaattaaaat atcagttaaa ataaaagtta aggagcattg
     5701 tgtatgacaa ttaaaactag tctccaaaat caagcttacc aatctattcg ccgacaaatt
     5761 atctatgctg acttagaacc tggaaaaaaa gtatcagaaa aaaaattaga agaaacactt
     5821 tctattggtc gtacaccaat acgtgaagca ctgattcaac tccgacaaca aggtcttgtt
     5881 gatacaattc ctcaaagcgg aaattatatc tcattaattg atttagattc ggccaaaaat
     5941 gctcgatttg tcagagaaca tttggaacga caaattatgt tagagtgttg tgccaaaatg
     6001 aataaccaaa aaaaacggat tttagaaact ataatttcag aacaagaaaa agctgttagt
     6061 caaaaaaatg ctcgtagttt ttttcataat gataatttat tccataaagc ttgttttgaa
     6121 attgcagagc gagaagaagt atggcaatgg ttagaaaata acaatacaca cttagaacga
     6181 tttcgatggc tacgagtaaa aacggaagga ttaaagtggg aaaaaattat ggaacaacat
     6241 tatcaactat ttgaggcatt aacaaaacaa gatccagaag aagctaactt tctaacatcg
     6301 ttgcatcttc atttaatgct taatgagcaa aatattgttt tagctactca tccaaaatat
     6361 ttcaaaaata tataactttt aactcttttt aaattaaatg gttgttctga tcagaaaaat
     6421 atcgcttgtt ttcttattat gtaatatatt tcataaacta ttctgcataa caactattgt
     6481 ttgtactttt tacattggat aactaattat gactgctgat aacttttgat attaaactag
     6541 tatctccaat acaaataaaa aatagatatc ttgttcatca aaattagttc gtggatactt
     6601 accttcattt acatcattca gcggtttccc attttctttt attctattat ttcattttct
     6661 aatagacttg gcttcatttc gcaatacttt ttttcaatag gcatcaaatt ggtgttgttt
     6721 agatatttag ttgtagtttt gtgacatgat aagtatgctc ctttttctct tttccactaa
     6781 tacaacgatc aaagggtgct tttttcaaaa aactagaaaa atcaaaataa gattcgtatt
     6841 ttgattctat atatcctgtt tcaactacat cttatatttc acaatagaat aaatagcctt
     6901 ttgcatagct gcttaactta taagaaattg caatttactt cttcaaagtg aaaacgaata
     6961 tgagtaaaat aaaattattc ttcttacaga taattaaaaa tagcgcgtaa caaaaatcgg
     7021 cattcaatca cataattagg attgatgccg attacttata ttctacgtat agttttagta
     7081 ttcttatttt ttatcaccag taaccaattg agaacagccc taaagcagaa tagtctttta
     7141 tctcaaaacg cttaatttca ggcttaggaa tatgaataat cttttgagta tattctttct
     7201 cttttaatct tactgaagaa ataccactgc c
//
LOCUS       DAZKCH010000107         7217 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000107 DAZKCH010000000
VERSION     DAZKCH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.109"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(229..906)
                     /gene="phoU"
                     /locus_tag="ACG84X_002525"
     CDS             complement(229..906)
                     /gene="phoU"
                     /locus_tag="ACG84X_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFP9128343.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            complement(919..1677)
                     /gene="pstB"
                     /locus_tag="ACG84X_002526"
     CDS             complement(919..1677)
                     /gene="pstB"
                     /locus_tag="ACG84X_002526"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFP9128344.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            complement(1693..2499)
                     /gene="pstB"
                     /locus_tag="ACG84X_002527"
     CDS             complement(1693..2499)
                     /gene="pstB"
                     /locus_tag="ACG84X_002527"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFP9128345.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDIHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            complement(2514..3398)
                     /gene="pstA"
                     /locus_tag="ACG84X_002528"
     CDS             complement(2514..3398)
                     /gene="pstA"
                     /locus_tag="ACG84X_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFP9128346.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVMKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            complement(3398..4318)
                     /gene="pstC"
                     /locus_tag="ACG84X_002529"
     CDS             complement(3398..4318)
                     /gene="pstC"
                     /locus_tag="ACG84X_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFP9128347.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            complement(4433..5290)
                     /locus_tag="ACG84X_002530"
     CDS             complement(4433..5290)
                     /locus_tag="ACG84X_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFP9128348.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            complement(5627..7075)
                     /gene="cls"
                     /locus_tag="ACG84X_002531"
     CDS             complement(5627..7075)
                     /gene="cls"
                     /locus_tag="ACG84X_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFP9128349.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
BASE COUNT         2093 a         1589 c         1255 g         2280 t
ORIGIN      
        1 ttgcattctt tatcctttct atgaaatgat gaaaagggtt tgtgacatgt tttgtcacaa
       61 accctttccc gaataaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaaa
      121 cgaaaaatat gaggagctat tttttgtttg actgttctta ttacttgatg tagaacagct
      181 ttttcacaac ctcttttcat aaacaaacgg cataatcaca gcttcagttt agaaaatctc
      241 attgtggttc gtatttaact cagtgatttt ccctgtagcc aagtagacga tccattcaca
      301 gatgtttgtc acatagtctc cgatccgttc tagataactg gcaacattca agtagtctgt
      361 tccactgatg actgtctcag gattttcctg catatttttg attgttgcat tatagattcg
      421 attgaaatag tcattgactc tttgatccat attggcgatc gtacgtgcgt ctttttcgtc
      481 tgttttgaca taagcaacta ggacgttgtc caccattttt ttcacataat cggacatatc
      541 ggagatctct ttttcgattt ccggtattct cgtctgccct tttacgcgaa tcgtggattt
      601 agcaacagac accgcatgat cggccatacg ttctaaatcc gagctagctt tcatgaccgt
      661 aatgatcata cgcaaatcag ttgtaactgg ctgttgcaat gcgatcattt caaaactttt
      721 cttctccaag cgtgtttcca tgttattgat atttatatcg ttttcgataa cttcttgggc
      781 taagatttta tcgtgtttga tgtatgcacg aactgacttg tgcacggcgc tgctcaccat
      841 catccccatt tcgtagaact gattatggag attcagcaat tcttcttcaa attgtgtacg
      901 tagcattccg tttcctcctt atccaaatcg acctgaaata taatcttctg tctcttgttt
      961 ttctggattc atgaatatct tcttcgtatc gttgtattcg atcaagtgac catctaaaaa
     1021 gaatgccgtc ttatctgaaa tacgtgaagc ttgagacata ttatgggtca cgatgatcat
     1081 cgtataccgc tctcttaatt ctaacagcat actttcgatt ttcccagtag aaacaggatc
     1141 aagcgcactt gttggttcat ccaataagat gatttccgga ttaactgcca aaacacgtgc
     1201 gatacataca cgctgctgct gcccgccgga taaagataaa gcacttttat gcaatttgtc
     1261 tttcacatca tcccaaacag acgctgcctt caggctttct tcaactactt gatcaaggac
     1321 ttttttatct ttttcccctt ttaatttcaa tccatagatg acattttcat agatagaaaa
     1381 aggaaatggg tttggctgct ggaataccat gccgatttct tttcttagtt caacaacatc
     1441 tgtttttgga ccatagatgt ctttgtcttt atataaaaca cttccggtga tcgttacatt
     1501 cggaatcagg tcattcatcc ggttcaaaga acgcagataa gtggattttc cgcaaccaga
     1561 aggaccgatc atcgcagtga tttccccttg attgaaactt agatcgatcc cttttagtgc
     1621 ttctttcttt ccataataca gatgaagatc tttagatgaa ataatttctt ttgtcatgtt
     1681 gaggcctccg tcttaaccaa aatgaccgga cacataatct tcggttgcct gaatttttgg
     1741 tctggtaaat atcttgttag ttttgtcata ttccattact tttcctagat agaaaaaggc
     1801 agtatagtcg ctgatacgag ctgcttgttg catgttatgc gtcacgatga tgatcgtata
     1861 gtcttctttc aagtttacaa gtgtttcttc aaccgttcct gtcgaaatag ggtccaaagc
     1921 acttgccggc tcgtctagca gcaagatatc aggtttcatc gcgatcgcac gagcaatgca
     1981 taaacgttgc tgttgcccgc cagataaagc caaggcactt ttgtccaagc tgtcttttac
     2041 ttggtcccac aaggcagctt gtttcaagct tgtttcaacg atttcatcta atttcttttt
     2101 gtttttttcg ccgtgctgtt tcaaagcaaa tgtaatattg tcataaatcg acttgctgaa
     2161 cggattagga cgttgaaaaa ccatgccaat ccgtttgcgc atctcataaa catccacttg
     2221 aggcgcatta atatctacgc cttgatacat gattttccca gtgattttcg tattagcgat
     2281 cccatcattc attcgattca acgaacgaag atacgtagat tttccgcagc cggaaggacc
     2341 aatcagtgca gtgatcttat ttttttcaaa ttccagatcc actcctttga ttgcttcatt
     2401 gtcgccatac cagacatgta tatcatccgt atatagtgct acttctttct cttttggcat
     2461 ggtgatgaca tttgtttcat tccagttata ttttttcatt ttgcttcttc tccttaggct
     2521 gaagtcattt ttcggtataa tcgtttgcca atcgcacgag cgccgaagtt gaacagtaaa
     2581 acagcaatga tcaacacggc agaagcgcca gccgaaacag aaacaccatc aggcatcgtg
     2641 ccttctgtat tgatcttcca aatatggaca gctaatgttt cagcttgacg gaaaatgctg
     2701 atcgggcttg aaacacttaa tggattccag ttcgtaaaat ctaacgcagg tgcactttgt
     2761 ccagccgtat agatcaatgc agctgcttca ccaaaaattc ttccagaact taggatcaca
     2821 ccagtcaaaa tccctggtgt cgcttctgga accaccactt tcatcactgt ttcccagcgt
     2881 gacaaaccta aggccaatcc tgcttctcgt tgtgtgtaat ggaccgcttg taaagactcc
     2941 tcaactgttc tagtcaaaag aggcaagttg aatacagtca aagccaatgc accagaaata
     3001 atcgagaaac catactggaa ttgaataacg aaaaccaaga aaccgaataa accgacaacg
     3061 acagaaggca acgagctcaa gatttcaatc gacgtgcgaa tcacatctgt tagccagttt
     3121 tttccagcat attctgaaag atagataccc gcacctaaag aaataggaaa actgatgatc
     3181 atcgtgatca aaagcaaata aatcgagtta aatagctgga tcccgattcc accaccttct
     3241 tggtaggctt tggaaggttc ggtcaagaag gaccatgaaa tgtgcggtat tccccgaact
     3301 aagatataaa gtagtaaagc tgctaaaatc aatacgatga tccccgaaac tatatataaa
     3361 acacctgtag caattttatc tgagcgtttt gcgttcatta tttcagctct cctttcttcc
     3421 caatcatacg gatcacgata ttaaagaata atgacatcaa tagcaagatc agcgctaatg
     3481 accataacac attattttca actgttccca tgattgtatt tccgattccc attgttaaga
     3541 tggacgtcaa tgtagaagca ggagtagtaa gtcctgttgg catcaatgct gcattaccga
     3601 tgaccatttg gatagctaag gcttcaccaa acgcacgagc cataccaaaa acgactgctg
     3661 ttaaaatccc gggcacggct gctcgtagca cgactttgta gattgtttgc catcttgtgg
     3721 caccaagcgc taatgaagct tcccgatagt gccgtggtac tgcctttaat gcatcaacag
     3781 tcatcgttgt gacagtcggc aagatcataa cgaacaacac aaatgtacca gctaagatac
     3841 caaaccctgt cccgccaaaa atacttctga caaaaggcac gataactgat aaaccgataa
     3901 aaccataaac gacagaagga atacctacaa gcagctcgat gaccggctgt aagatcttcg
     3961 ttccgttttt aggagagatc tccgtcatga atactgctgc accaatggca aatggcgtgg
     4021 caacgatagc agataaaaag gtcacaataa acgaacctgt gatcataggc aatgccccta
     4081 ccattggttt cccatttgct ccgatttggc ttggattcca atctgtacca aacagaaaat
     4141 caaatacatt gatcttatca gtaaaaaagg tggccaatcc tttactagct acaaaataaa
     4201 aaatagataa tacaaccaac acgatcagcg cgatacataa aaaactgatg aattttccac
     4261 gctgttccat ttttgaacgt tttgattttg ttaataatac ttttttcaca tcttccacag
     4321 atgactcccc cttaatcagg tttaacatac tcactcagtg tacaaattga acatcaattt
     4381 ggttttaata acatgtaaaa gtttagctaa gtttgtaaat tttgtgtaaa gattactctt
     4441 taacgatatt tccttgccaa tcacgttcga ctttcatatg agaaacaggg atataaccta
     4501 gttctccaac gatgttatct tgtacttcat cagataagat atagtctaaa aattcttttg
     4561 tcagtttttt tggatgatct cttgtgtaca tatgctcata tgcccaaatc gtccatttgt
     4621 tcgttgtcac attttcatct gtcggttcta caccgttaac attcaacgta tctacatcat
     4681 cggaaacata agaaaaagca acatagctga ttgcaccggg tgtgtcggca acgatctggc
     4741 gcaccattcc gcttgaatct tgttcttgtg cctgaacagc tgtttctccg tccaataccc
     4801 atttttcaaa cgtgctacgg gttccgcttc ctgaagcgcg gttcaatata actactggct
     4861 gatcttttcc accgacttca ctccagtttt tgatctcgcc tgtaaatagt tttttcaggt
     4921 tttccatact gatgtctttt acgccaatat ccttgttcac aataggagtg atcccaacaa
     4981 ctgctactcg atgatcgact aatgctgagg catcgatccc cgatttttct tccgcaaaca
     5041 aatcagagtt tccgatgtcg actgctcctg actgtacttg agacaaacca gttccgcttc
     5101 cgcccccttg tacattgatg aattttccag gattttctgt ctggtaagtt tcagcaactg
     5161 tttctactaa aggctgtaaa gcagaagagc caacagccgt aatggattct cctcgatcaa
     5221 tccactttga acagcctgat aaaagaatgg ctaatcctat tattggtaag aataatttaa
     5281 gttttttcat tagaaatctc ctttaatcct aaagtatgtt tattttatca ttttcattac
     5341 ttgatgaaaa cgaatcaaaa tcattaaata acaaaataaa ttctcataat tgtaaaaaaa
     5401 actatctcat taaaagtttc tatgctatac tggctttgaa atgtgtctct tttaatagca
     5461 tatattagct tatttcttgc tttccccaaa aaacaagaga taccccaaag ttaatttcgc
     5521 tcatgcgaga cgctttctcc atttctgacg tactctcaga aatggccccg ttagaaaagg
     5581 acacgagatc tccatctgtt gatggttctc atgtcctttt tatgttttaa aggagcggcg
     5641 aaatcaatct tgctaatcct tctttcatct tgatgattat tcctcggttt tcatacattt
     5701 cttttgtgag atgcgtagaa attttcgagt cttcaaaaaa agcttttctt acacgtgaag
     5761 ccattcgttc atcataaacc agtgtattga cctcaaagtc caagcgaaat gaacgaacat
     5821 cgatatttgc tgagccaact gaaacaatgc caccatcgat aatcatcgtc tttgcatgaa
     5881 taaatccatt ctcatatgtt tcgatccttg ctccatactc gatcagctct gcagcgaaag
     5941 aatacgttgc ccagtaaacg agaagatgat ctggtttgtt aggtatttgg atatgaactt
     6001 ttacgcctga aagaagagcc aacttcagtg cttcatgaat cgatccatcc ggtatgtaat
     6061 aaggcgtttg gatcaatatc tcccgtttgg ctaacgaaat cattttcaaa taagtcattt
     6121 tgatttgttc atgttcggta tctggtccgc ttgtcacgat ttgaacagct atatcaccag
     6181 tagtgtgaat ggacgggaaa aatttgggag aatagcctac ttcttttgta tgctgagaat
     6241 tccagtccat caaaaaacgg ttttgcaagg tatacaccgc ttctccgtaa atacgcaaat
     6301 gattgtctcg ccaataacca aatttcttta ccaatcctag atattcattt ccaacattga
     6361 acccacctgt atatccgatt ttcccatcaa taactacgat tttacgatga ttgcgataat
     6421 tgatccgagg attaatatac ggaacaaata gaggaaagaa aaatgcgact tctccgcctg
     6481 cttttttcaa attctgaaaa aagctggaag aaacttgtgt ggaaccccat gcatcaagaa
     6541 ggactctgac ttttacccct cgtcttgccg cctctgtcaa tgcatctcga acttcttcac
     6601 ctaatgcatc actgcgataa atataatact ggaagtggat atggtcttct gcctgcttga
     6661 tatcttcaat cagcgcatcg aatttttcac gaccatctgt aaataaagtg atttcatttt
     6721 tagtcgtata gagcgtactt tcaaataccg tgagcatata gatcaattgt ttcacatcta
     6781 cttgtccagt aggcggatga ggataaagcc ctcgcatcaa tgcctgtttg tcttcttcaa
     6841 tttccaggtt cttaccgatt ttcccttgga tcttcaaatc aaagattttc tctttggaaa
     6901 tccctcttcc taaaaaaata tataaaataa atcctacaac tggaatgaac atcaaaacga
     6961 gcagccatgc ccatgtttga gcagtttcct ttctttctcg aaaaacgatg ataaaggaaa
     7021 gcaaaatatt cataatcaaa aggatcgtaa aaaaattgtc aacgataatt ttcacggctt
     7081 cacctcttct tctaccaact taagaatacc caagttgttt tttaaagtaa agggaaaaaa
     7141 gccgcttcct tctattctcc tagccaataa aaaaagaaag ctggaacgaa actgtccaac
     7201 tttctcattt tatttat
//
LOCUS       DAZKCH010000108         6854 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000108 DAZKCH010000000
VERSION     DAZKCH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.110"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..521
                     /locus_tag="ACG84X_002532"
     CDS             <1..521
                     /locus_tag="ACG84X_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphoesterase"
                     /protein_id="HFP9128350.1"
                     /translation="LISEYKNEIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLK
                     KQVEKLSHKSYKDVYDEYSKETDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVT
                     DEIDEHRGELIKNLVTNRAKIQTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRG
                     IKNLVKSYLKMN"
     gene            524..1420
                     /locus_tag="ACG84X_002533"
     CDS             524..1420
                     /locus_tag="ACG84X_002533"
                     /inference="COORDINATES: protein motif:HMM:NF024700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9128351.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNFYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            1470..1859
                     /locus_tag="ACG84X_002534"
     CDS             1470..1859
                     /locus_tag="ACG84X_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFP9128352.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            1846..3345
                     /locus_tag="ACG84X_002535"
                     /pseudo
     CDS             1846..3345
                     /locus_tag="ACG84X_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            4093..5919
                     /gene="ltrA"
                     /locus_tag="ACG84X_002536"
     CDS             4093..5919
                     /gene="ltrA"
                     /locus_tag="ACG84X_002536"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFP9128353.1"
                     /translation="MLKKNKLRYNEYYDMQHIYDELYAQSKNGNNFYKLLEIIGSEQN
                     ICLAYRNLKSNSGSKTAGTDGMTIDDIKQLSNAEIVATVRESLSNYRPKSVRRVFIPK
                     AGSDKMRPLGIPCIWDRLVQQCILQVLEPICEPKFHNHSYGFRANRSAHHAVSRVTTL
                     INLSKYHYCVDVDIKGFFDNVNHGKLLKQIWTLGIRDKRLICIISKMLKAEIDGEGVP
                     EKGTPQGGLLSPLLSLIVLNELDWWVSSQWETFQPKNRSKNGWLQYAKKYTKLKSGFI
                     VRYADDFKIMCSTYGEAQRFYHSTVDFLNKRLKLEISPEKSKVVNLKKNSSDFLGFKI
                     KVIPKGRTKHGYVAKTDMNQKALKKAKTNLKLKVKDIARHTTGFNISRYNLTVIGMQN
                     YYCIATNVYNNLTEVSYALLPTIRIRLRNIAKSVPFESTSSEFQSRTKGIRPKTKIVM
                     IADNPLLPIQGVQHKNPMNFSQDICNFTKQGRNKVHEDVVVVTKEEIRALLENENPAD
                     SVEFNDNRISAYIAQQGNCYVMNRRGTPSTLICIHKSDKGDNLDRYSNLAFVEIPIAK
                     AILTESADEAKSLLKGYVLNSQQKKKLNRIRTNYGYQTITGK"
     gene            6032..6854
                     /locus_tag="ACG84X_002537"
                     /pseudo
     CDS             6032..6854
                     /locus_tag="ACG84X_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
BASE COUNT         2389 a         1114 c         1469 g         1882 t
ORIGIN      
        1 atttgatttc agagtataaa aatgagattg aaacatgtgt aaacgaaata agaaaattaa
       61 attgggatat tgtttctgtg aaaaaagaaa tacaagataa ggcgaaggta gagcttgaaa
      121 ttgaagattt aaaaaaacaa gtagaaaagc tatctcataa gagttataaa gatgtttatg
      181 atgagtattc aaaagagaca gatatttata gggaactgaa acgtgatgtg gaggcactta
      241 aggaaattcc caaaaatcta actgatagtg ttgacaaaat tgactttggc aatggtataa
      301 aagttacaga cgaaattgat gaacaccgcg gagaattgat taagaattta gtgaccaatc
      361 gggctaagat tcaaacaata attaatgaaa tgtcagatga aattgatagt tatagagcag
      421 agctgaataa atcagattgg aaagttaact ataatgaggt ttcaaagagg tatcaaagag
      481 gtatcaaaaa cttagtgaag agttatctca agatgaatta aaaatgttac aaaaccttga
      541 ttctttatat caatctttat caaaaactga agagcgattg gaagaaatta ttcaacaaga
      601 aataaagctt aaagattacc aagttgaggt tgactcagca atgtcaagaa tgaataaatc
      661 atatcaaaat ttctattctg agagaagtag ttcctcgcgc gaaatttttt ctgatattac
      721 aggaatagag gctactattc aaccaaatag ggatttcaat aattatgtta aagagctcag
      781 agcttgtatt aataaggagg acacttttga cagtgagttt ggatctctta ttgataagct
      841 gacaaaaaat tccattacta atcaagatat atataatgac atacttgata taagagttag
      901 tggggaaagt agtatttttt cagataaaaa attaatcaat tctataagaa aattgaatga
      961 tgcacaagtt cttgaattac aaacccttaa gccaaatgat ttagtagtta tccgacttga
     1021 actaaatgga aaaaaagtta gtttatcgaa tgctagtgct ggtcaaaaga catctgcaat
     1081 tctttctatg attttggcgt atggaaattc accactcata ttggatcagc ctgaagatga
     1141 tttggatagt caattaatta ataacttaat cgtaagaagt atcattacaa aaaaggaaaa
     1201 cagacaaatt ttaattgtaa ctcataatgc aaatatccca gttaatggtg attcagaatg
     1261 gttgattagc atgggagatt caaaagaaat atcggctgat cagtgcgggt cggtagatga
     1321 acccaatatc aagccaagaa tatgtactgt gatggaaggt ggcgaggatg cttttacaaa
     1381 tagagcgaaa cgctatggtt ttaaacaaat tgtagaataa cactagaggg tgagacatat
     1441 tattatgtcc gcccttttta ggaggaaaaa tgaaaaaaat aaaaagctat accagtatct
     1501 gggcagttga aaaagtcatt tacgcaatca atgattttca gttgcctttt cctgtgactt
     1561 ttaaccaaat ggcttggttc gttttatctt tactgtttgt catcgtattt gcccatgtgc
     1621 ctccactatc tatgatagag gaggtctttt taaaatactt aggcataccg gtggctgtca
     1681 cttggtttat gtcgcaaaag acgtttgatg gcaagaaacc actgggattt ttacgatcct
     1741 ttatcagcta tcacttgcga tttaaggtga cttttgcagg aaagaaagtc aaagaacaga
     1801 agaaacgatg ggatgaaccc agtactcttg taaggagtgt gaactatgta tccgattaag
     1861 tatattgaaa ataatctcgt ctttaaccaa gaaggcgagt gttttgccta ctatgaatta
     1921 gtgccttaca attactcctt tttgtcaccc gaacagaaat ttcaagtgca tgataacttt
     1981 cgccaactaa ttgcgcaaaa tcgtgaaggc aagatccatg cgttacaaat tgccacagaa
     2041 agtagtattc gcgccacaca agaacgatca aaaaaagaaa ttaccggtag actcaaagaa
     2101 gtagcgaaac aacgaattga tatacagaca gatgcattag tatccatgat tggcgatagt
     2161 cagattgatt atcgcttttt tattggcttt aaactaattg cgacagatga agaagtcaat
     2221 ctaaagagtc tcaagaaatc tttcttttct gggcttcaag aatttgtcta tggagtgaat
     2281 catcatttga tgggcgattt tgtttcctta tccaatgaag aaattcgctg ctattctaag
     2341 cttgaaaaat taatggaaag caaattggct cgaagattta aagtcaggcg agtcacaccg
     2401 agtgacctga cgtatttgat tgaacatatt tatggcgaaa aagggatacc gtttgaagaa
     2461 tacgaatttc agctaccaaa gaaaaagcta aaatcagaaa cactggtgaa acgttatgac
     2521 ttattacgtc caaatcgttg tttaattgaa gaaaaaccaa ggtgcttacg gatggaacat
     2581 gagaatcatg agtcgtacgt agcgtattta acaattaata caattgtggg ggagatggaa
     2641 tttccttcct cagaactttt ctattaccag caacaacaat ttacattccc aatcgacaca
     2701 agtatgaatg tagagattgt gacgaataaa aaggctttag ctaccgttcg taataagaaa
     2761 aaagaactga aagatttaga caatcatgct taccaatctg acaatgaaac gaattccaat
     2821 gtcttagatg ctttggattc cgtggatgaa ttggaaacca ccttggatca gtcaaaagaa
     2881 tctatgtaca aactgagtta tgtggttcga gtgagtgccg aatcagtgga tgaactaaag
     2941 cgacgctgtg atgaagtgct cgatttttat gatgatacca atgtaaaact agtccggccc
     3001 tttggcgata tgatggggct acatgaagaa ttcttaccct taagtaaacg atatatgaac
     3061 gactatattc agtatgttac gtctgatttt ttggcggggc ttggttttgg ggctactcag
     3121 atgctaggag aattagaagg gatttacttt ggctacaatg tggatacagg tcgtaatgtt
     3181 tacctgaaac cggcattggc ttcacaagga gtcaagggtt cagtaaccaa tgcgctggcc
     3241 gccgctttcc tgggttctct tggtggaggt aaatccttta gtaacaatct cttagtctac
     3301 tatgctgttt tgttcggtgg tcaagctgtg attgtcgatc caaaaggggg tgcgaaacgt
     3361 tcctacttga aaagagtagg cacagcactt cattaaatca atatttaatg tgtgttggag
     3421 aactaaacac acgaatagtc gaatgacggg gtaacgccct gaaaggctac tttaatactc
     3481 tgactggcag aaacttgagt aaacaaggct ctgtcagaag ctcggtgaag tcggcagaca
     3541 gacaccgtaa cagataatgc tgacgaaaga ttcccagagg tgggcgttgt gtcctatatg
     3601 ccggaagtct ataaaatatc tatggttaga atgtagatga gaggtctact gacgaatcct
     3661 tgaatgtaca ggtctatatc ggggctggat agaaatgtcc agtgacacaa acagtgtcgc
     3721 tactgtgggt gagtaagact ccgcatttat gaaaatccat ataacgttaa aggcgttatc
     3781 aaggtagcag gcttatagag gaaacctaag gatatatgta cagatagtgt gtttggaacg
     3841 ttgaaagctg acaacatgga gattttactg tctgtgaagt gttcacatca gaaagttatt
     3901 gtgagattag caatgatata aggtgtgtta atgtcagtga gagtggtggc acagtaccta
     3961 tgaaaccgtg ataacaagcg gtggagggat agccactagt catatgaaga atagaattac
     4021 taagaaaaat ggtatgggtt cgagtaagac taagagatgt acttgctcct gcaaacaagg
     4081 agggtacaga ccatgctaaa gaaaaacaag ctccgctata acgagtatta tgatatgcaa
     4141 catatttatg acgagttata cgcacagagc aagaacggta ataactttta taagttactt
     4201 gaaattattg gttcggaaca aaatatttgt ttagcttacc gtaatctgaa atcaaacagt
     4261 ggcagtaaaa cggctggaac ggatggaatg acgatagacg atataaaaca actcagcaat
     4321 gctgagattg ttgctaccgt tcgggaaagc cttagcaact accgccccaa atcagtcaga
     4381 cgtgttttca ttccaaaagc tgggagcgat aaaatgcgtc cattggggat tccgtgtatc
     4441 tgggacaggc tggtacaaca atgtatcctg caagtcctag agccgatatg cgaaccaaag
     4501 ttccataatc attcctatgg attccgtgcg aatcgaagtg cccaccatgc agtcagcaga
     4561 gtaacgacac tgataaattt atcaaaatat cattactgtg ttgacgtaga cattaaagga
     4621 tttttcgata atgtcaatca tggaaaacta ttaaaacaaa tctggacact tggtattcgg
     4681 gataaaagat tgatttgcat tatcagcaaa atgctgaaag ccgaaattga cggcgagggt
     4741 gtcccagaaa aaggaacgcc acaaggcggt ctgttaagtc cactgctctc cctcatagtc
     4801 cttaatgaat tagactggtg ggtaagcagt cagtgggaaa cattccagcc gaagaaccgc
     4861 agtaaaaatg ggtggcttca atacgcaaag aaatatacca aactgaaaag cggttttatt
     4921 gtacgttacg ctgatgattt taaaatcatg tgttcaacct atggagaagc acaaagattt
     4981 taccacagta ccgtagattt tcttaataaa aggctgaaat tagaaatcag tccagagaaa
     5041 tcaaaggtag taaatctgaa gaaaaattca tcagattttc tggggttcaa aatcaaagtc
     5101 attccaaaag gaagaacgaa acacggttat gttgccaaaa cagatatgaa ccaaaaagca
     5161 ttaaagaaag cgaaaacaaa tctaaagtta aaggtaaaag atatagccag acatacgact
     5221 ggcttcaata tcagcagata taatctgaca gttatcggta tgcagaatta ctactgcata
     5281 gcaactaacg tatataacaa cctgacagaa gtaagttacg ctctcttacc gaccatacga
     5341 atccgtttaa ggaacattgc aaaatcagtt ccatttgaaa gtacaagttc agaatttcag
     5401 agcaggacaa aaggaatcag accaaaaaca aaaatagtga tgattgcgga taatccgcta
     5461 ttgccgattc aaggagtaca acacaaaaat cctatgaatt tctcgcaaga tatttgtaat
     5521 tttacaaagc aagggagaaa caaggtgcat gaggacgttg tagttgtaac aaaagaagaa
     5581 atccgagcgt tgttggaaaa tgaaaaccct gccgatagcg tagagtttaa cgacaatcgt
     5641 atttcggcat atatcgcaca acaaggcaac tgctatgtaa tgaatcgtcg aggaactccg
     5701 tccactctga tatgtattca caaatcagac aaaggagata accttgacag atattctaat
     5761 ctggcatttg tggaaattcc cattgcaaag gcaatcctaa cagaatcagc agacgaagca
     5821 aaatcactgt taaaaggtta tgttcttaat agtcagcaga agaaaaaact gaacagaata
     5881 cggacgaatt acggatacca gacaataact gggaaataac ttataaatct atttggatat
     5941 gatggaacgc cgtatgaagc gaaagtttca tgtacggtgt gaagcggggg aaaacttgga
     6001 gataacatca aaaagttacc tatcgctata gcgaggaggg tggaaagaaa ccttgccaga
     6061 aattgcggat gaaatcagta tcctcaactt gacgagtaag tcagaaaatc aaggtctgct
     6121 tgatccttat gtgattatga agaaaaagaa agactcggaa agtttagcaa ttgatattct
     6181 gactttttta acaggaattt caagtcgaga cggggagaag tttcctgtgt tacgtaaagc
     6241 cattcgaacg gtgactcaaa gtgatcaacg ggggttatta caagttatta acgaattgcg
     6301 aaaagacggg tcaccaatcg cggaaaatat cgccgatcat atcgagtcct ttaccgatta
     6361 tgattttgct catttgcttt tctcagacgg ctcgattacc caatcgatta gtttagataa
     6421 acagctaaat atcattcaag tggcggattt ggttttaccg gatgcagaaa cgacttttga
     6481 agaatatacc accatggaat tgcttagtgt ttcgatgcta atcgtcattt ccacttttgc
     6541 cttggacttt atccatagta accgagaaat cttcaaaatt gtcgatttgg atgaggcttg
     6601 gagttttctt caagtggctc aaggaaaaac gttatcgaat aagcttgttc gtgctggtcg
     6661 ggccatgaat gctggggtct atttcgtcac tcaaaatagc gacgatttat tagatgaacg
     6721 tttaaaaaat aatatcgggt tgaagtttgc ttttcgcagt accgatattc atgaaatcaa
     6781 gaaaaccttg gaattctttg gtttggatca ggaggatcaa agcaatcaaa aacgcctgcg
     6841 agatttggaa aacg
//
LOCUS       DAZKCH010000109         6788 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000109 DAZKCH010000000
VERSION     DAZKCH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.111"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            528..722
                     /locus_tag="ACG84X_002538"
     CDS             528..722
                     /locus_tag="ACG84X_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128354.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            913..1162
                     /locus_tag="ACG84X_002539"
                     /pseudo
     CDS             913..1162
                     /locus_tag="ACG84X_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1406..2236)
                     /locus_tag="ACG84X_002540"
     CDS             complement(1406..2236)
                     /locus_tag="ACG84X_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFP9128355.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            2444..3778
                     /locus_tag="ACG84X_002541"
     CDS             2444..3778
                     /locus_tag="ACG84X_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9128356.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            3819..4730
                     /locus_tag="ACG84X_002542"
     CDS             3819..4730
                     /locus_tag="ACG84X_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9128357.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            4792..5580
                     /locus_tag="ACG84X_002543"
     CDS             4792..5580
                     /locus_tag="ACG84X_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9128358.1"
                     /translation="MTVIGIILIIPLLWMVFTSLKPMEEIVRYPPTFFPEKIVWENYL
                     DTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYGFAKLDFPGKKLMFALVLSTMMI
                     PGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFNIFLMRQFYLSINNELIEAAEID
                     GANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFLGPLLYIQDQEKYTLQIGLQVFQ
                     NQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGMDLTGGSKG"
     gene            5577..6193
                     /locus_tag="ACG84X_002544"
                     /pseudo
     CDS             5577..6193
                     /locus_tag="ACG84X_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            6195..6713
                     /locus_tag="ACG84X_002545"
     CDS             6195..6713
                     /locus_tag="ACG84X_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFP9128359.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
BASE COUNT         2039 a         1182 c         1366 g         2201 t
ORIGIN      
        1 gttattttat aataaagata tgatgactaa tttagctcaa ctattccagc gtcagctgaa
       61 gatattgcaa ttcccgattc cttaatcatt tatctggatg agacagaaag tgaagttgca
      121 acagatgtgc atgtagttga ggataaaaat gatagtttaa aaattaatag ttcagatact
      181 ttactaagag taagtcctat cttttcagct gttatttaga tgcaagtagc aactaagtta
      241 ggtagtactc ctgcaatgga taggtatttg tgtgttcgat atataagtgg tcgaagtatc
      301 aaggttatgt atactggatg ggagatagaa gagttaaaaa ttggaggtca ccgccacaaa
      361 tggaatttag atttagaggt accttagatt tggtatagtt attaaacaca agatggcctg
      421 gtttgtaggg aaagtcgaag agtatttttc cacttctgcg cccctttaat ttttctagta
      481 atgccgtgaa tttgtgatta attggaaata tgaagaaagg agagtctatg aaaacaacac
      541 tagttctatt ctataaaaag catccttatt ttacacttct gataaatata ttgttggcta
      601 gtgttatcgg gatttctgtt gaatatctaa taaataaaga tttcataggt tcttgttttt
      661 atacggcttt atttcttgga cttcttgaag cattttccat ttataaaaaa tcaaaaaaat
      721 aaaatagatt gccgtaagag atctttttca tttcattttt ttctgaaaac ccgttgtttc
      781 tgtcagtgaa gcagcgggtt tttagattta ttgtctttag acctaattga gcgcgccgag
      841 cgattgaaat acaaaaccac ttgctatgcg ggtggagcaa taaagggaaa tagtttagcc
      901 cgtacaaagt agatgtgtaa ataccacatt gtattcacac caaagtatag aagaaaaata
      961 atttataatc aatatcgagc caatattcag gagatcatca agagattgtg caaatctaaa
     1021 atataaattt gggtatcgac acttttgggt ggaaggatac tatgtgacaa aagtaggaca
     1081 aaatgaagcg accatcaaaa agtacattca agaacaagaa aaacatgata gtgcgttaga
     1141 taagctgagt gtacgagagt aagacgatcc ttttaagggc taaggagtag tacataaacc
     1201 ttttaagagg tgggcaaaac tggcaaaggc aatatggctt gaacataaaa tatgaaagcc
     1261 agcgtcttta ggcgctggcc ggtgatttga gcttatagct ctagagaaaa ccaccctttt
     1321 gaagggtggt tatgattaat gactttagtc agttttgctc acaaagcgtg tggaacaaaa
     1381 aacgggtgtt tctacgggta gatatttatt tcttgaatgg aggtgtccca tacatttttg
     1441 gtgttactgg ttctaatttt ggtgcagcgc cttcgatctt aggttctttc aaccattgat
     1501 attcgccttc gccatccagt gctttgccac tagcccaaga accttcacta ctttggtctc
     1561 cctctgagaa gttatagaag tcataagcaa tgtcttttcg ttctttgtca cgcgggaaag
     1621 tacttgggac taagattgaa ccttcttttt cttctaattc tttcactgca cattcccata
     1681 gattttgatg atagctatct cttgcaagga gaacagacag catatctttt acgccacgat
     1741 catcgatcat ttcgtaaata cgtgctactt gaagtcttcc ttgtgattcg gcatttaaat
     1801 tagctctaaa gtctgctaac aagttgccac tcgcaatgat ataggcaccg ctccatggat
     1861 tgcccacgct gtcagcagga cgaggtccta agccagctac gatcgcgtgc tgtggattca
     1921 ttccagagat aatggcaccg attgttggat ctttttgcat cgctgcttct tgatcttcaa
     1981 caggcgcacc ctctaataaa cgagcaacca ttgtcgccaa catttccacg tggccgattt
     2041 cttctgttgc aatgtccatc agcatatctt tatatttttc ttctcctcgg cagctccagc
     2101 cttggaacag gtactgcata gctacactca tctcgccata ttggccgccg atcagctcct
     2161 gcagatattt cgcgattaat ggattcggac gatctggttt tgcttcaaac tgcaattctt
     2221 tctggtgtct aaacatcaaa attcctccta atctattttt aatacattct cattctgcta
     2281 cgaaagatta aaaaattcaa agaaagcgct cgcgaattat ataaagtatt ggtatcatta
     2341 ataatttttt tagaatcata ccttataaat tgttattttc agaacaaaat gatatcgtta
     2401 tattaaaacc ggcatcggtt acattaaaat ttggaggtaa aatatgaaaa aattattgtt
     2461 tacagggttg ctggcaagtt cagcattgtt tttattagga ggatgcggat caagtaatgc
     2521 aagcgatgcc agttcaagtg cagcaaattc ttctgaaaaa acaagtgatg gaagaaaaaa
     2581 tattgatttc tggtcctttt ggggatccgg tgcacgaaaa gaagctatcg aagaaatcat
     2641 tgaggatttc aatcaatcac aaaacgagat ccatgtaaat tataagtatc agccatgggg
     2701 tgacatctgg actaaatctt tatctgcaat aacagctgga aatgcacccg atgttattgt
     2761 acaggacata aattccgttg cccaaagagc agaagcacag caagcaacta atctctccaa
     2821 atatgtagaa aaagacactt ctaaggattt ttatccgcag ctttgggata cagtagaata
     2881 tgaaggtgat ccttatgcga tcccattcaa tacagataca caagtcattt tttataataa
     2941 aaagatattt aaagaagctg gaatcagtga acaagatcta ccgacaactt gggatgaatt
     3001 agaagaaaca gcacgtaaac tagataaaaa agaaggaaaa gaatttacac gcatcggttt
     3061 ttatccatta tggaatttag gggctgatgt atgggcgcta aacgcagata acgggactag
     3121 ttggtttgac aaagatgaaa aagtcaagat tgatactaaa aataaagtgg aagccttgga
     3181 gtggatccaa gactggcaag attattatgg gaaaaatacg atcaataaat tagaagccga
     3241 atttgggtct ggtgtatctg atccatttat ttccggatta gtagccatgc gtgcccaaaa
     3301 tatcaattat tactctagtt tgatggaaaa tgcaccggat gattttgatt ttggcgtgat
     3361 gcagctccca gaaaaagaag aaggttcagg ccattggtcg tggggtggcg gattcgtctt
     3421 ggaagtacca tacggagcaa aagatcctga ggcctcttat gaattcatca aatatctttc
     3481 ttctccagaa gtacaagaaa aattcggcga aaaaagtttt gatatcatgg cgagcaagac
     3541 agccaatgag aatttagtga ataatgacaa cctaacggat aaaggaaaaa tgatctatca
     3601 aatggcggac gaaaacttta aaaatacggt gatcacacca gttcctttag atgctccgga
     3661 ttacacgaca ttagtgaatg aacagattga ccagattctt ttaggaacaa aatcaccaaa
     3721 agaaggattg gcagatgcac aaaaagcagt agaaaactta gtcaagcaaa atcaataatc
     3781 catttttgac tgtctaggta cagaggaggc aagaaaattt gaagcgttta tctatccgaa
     3841 agaaaaaaga agcaagatgg gcctatttat ttatctcgcc ttttattatc gggttcttgg
     3901 tatttatgct agggcctatg cttttttcag ttattggtag tttcaccgat tataatttga
     3961 catccaagat gaatttcatt ggtctagcaa atttcaaaag aatgttcgtt cacgatgatt
     4021 tattttggaa atcgttatac aacaccgttt atttcgtcat cttcaatgta ccgctgacga
     4081 cgattttcag tgtgttttta gccacagtac tcaatcaaaa aatcaaagga atcagtgtat
     4141 tccgtacagc tttctattta ccggcagtct tatcaggagt agcagtctac atcttatgga
     4201 tgcagctgct ttctccatct gcaggattga tcaacacatt tctgggctgg ttccatatcc
     4261 ctggaccagc ttggctgttt gatccacaat ggacgaaacc tgcgttgatt ttgatgaaaa
     4321 tatggagttc tggaggagca atgctacttt acttagctac attacaaaat gttcctagat
     4381 ctttatatga atcagcagaa atcgatggag caggcgtttg gggaaagttc aaaagtatta
     4441 ctttgccatt aatcactcct attatttttt acgatgtgat cacctctacg atcggttctt
     4501 tccaaatttt tcaagaagct tatgtcatga cgaaaaatgg aacaggcgga cctgcaaatt
     4561 ctttgctttt ttataatctg catatgtgga acaaggcgtt cgtagctttt gatatgggtt
     4621 atgcgatggc tatgtcaatg atcctgtttc tgatcgtgtt ggttctgacg tttgtcaatt
     4681 tgaagcttgc acctaagtgg gtctattatt ctggaggtga cggcaaatga tggattattt
     4741 caaaaagacc agtgtgaatc ggcaaacaaa aaaatactaa gttatgtcct catgacagta
     4801 ataggaatca ttttgatcat tccattgctt tggatggtgt ttacttcatt gaaaccaatg
     4861 gaagaaatcg ttcgttatcc tccgaccttt ttcccagaaa aaatcgtatg ggaaaactat
     4921 ctggatacga ttgccgcctt tcctttttgg cgctatgcaa gaaatacatt attcatcact
     4981 gtgctagtag tgatcggtaa tgtcctttca aattctttta ttgcttatgg atttgcgaag
     5041 cttgattttc ctgggaaaaa gctgatgttt gctttggttc tttctacgat gatgatcccg
     5101 gggtttgtaa cgatgatccc tcaatatgta ttattctcca agatcggctg ggtaggtact
     5161 tatttgcccc tgatcgttcc atcgttcttc ggcaatgcgt tcaatatatt tctgatgcgt
     5221 caattttact tatcgatcaa taatgaattg atcgaagctg ctgaaatcga cggagcgaat
     5281 catttgtata tttggagtca tttgatgctt ccattgacga aacctgcctt gattaccatt
     5341 gcgatcaatt ccttcaacgc agcttggaat gatttcttag gtcctctgtt atatatccaa
     5401 gatcaagaaa aatacacgtt acagattggc ttgcaagttt ttcagaacca agcaacgaca
     5461 caatggaatt atctgatggc aggagcaaca cttgtcttga tcccgacgat tttgctgttc
     5521 ttttttgcac aacgttattt cattgaaggg atggatttga caggaggttc aaaaggatga
     5581 tgaatcgatc gattggtaaa aaagccaatg attatttctt agaaatcatt gaatggattc
     5641 cacgtcttat ccatttacag ctactatggt tcctgtgcgt cttgcctgtt ttcacattag
     5701 gaactgcaag tcgaacagtt ctgtatatga tttatcatta caaaaaaatg aagagaaaaa
     5761 gctcggttca ctattctgga aaaagtttcg tgagaacttc tctctttatg gaaagcaaga
     5821 tagtttagca agtgtttatt ttcttcttct attgatcgat tatcagattt tccgctattg
     5881 gggtggggga attggctata cattgatgta tactacgttg tttttgcttc tattaagcgc
     5941 gcttctcttt agttacaaaa tcttgcttca actggaacaa aaagaagctt cttggattac
     6001 tgcatttttc ttgtttttta atgatttcaa aagcgcgctt ttctatttgg caggcacgtt
     6061 gatccttctt gtcgcattct ggtttgcagg accaatctat tttgctttat taggtttcag
     6121 tttcttgttt tattttcaag tcctgctttt tatccatcgt acgcaagaaa aggttcttaa
     6181 aaaggaggaa taacatgttg cgtttgattg ctaaaatcga tgatagtatt atcaacaagt
     6241 tcgccaagca acggaaaacg gatagtcgaa aaatcaattt tttgaaattt atcagtaata
     6301 tctctaatgg tggttttatt tggttgctcc ttgctgctgt tttagtcttg atacctgata
     6361 ctagagaata tggtctagcc attcttatcg gcagtttgat ctattttttt gttggtttgc
     6421 tttttatcaa aaaaacgaca agacggaaaa gaccttatga aaaaaatcgt cggcttgtcc
     6481 tttacacaag taaaccgaag acttcttctt ttccttcagg acatacagcg ctagcctttt
     6541 tatcagtagc tgcgttgttc gaattaagtc cagttgcagg aatattagcc tttttatttg
     6601 cttgtttgat cgcttattcg aggatttttt tacttttaca ttatcctact gacattttag
     6661 gaggagctat tttaggaagt gttattggca tcctatgcgc tgccgttatc tgaattaatt
     6721 gtacgaataa agcatgagtg cgtaaatgcg catttgtgct ttattttttt gtttcgagga
     6781 aagcgtag
//
LOCUS       DAZKCH010000110         6715 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000110 DAZKCH010000000
VERSION     DAZKCH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6715
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.113"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            8..898
                     /locus_tag="ACG84X_002546"
     CDS             8..898
                     /locus_tag="ACG84X_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFP9128360.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(971..1795)
                     /gene="nadE"
                     /locus_tag="ACG84X_002547"
     CDS             complement(971..1795)
                     /gene="nadE"
                     /locus_tag="ACG84X_002547"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFP9128361.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1807..3279)
                     /locus_tag="ACG84X_002548"
     CDS             complement(1807..3279)
                     /locus_tag="ACG84X_002548"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFP9128362.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(3916..4278)
                     /locus_tag="ACG84X_002549"
     CDS             complement(3916..4278)
                     /locus_tag="ACG84X_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFP9128363.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4501..5253
                     /locus_tag="ACG84X_002550"
     CDS             4501..5253
                     /locus_tag="ACG84X_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFP9128364.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5393..6316)
                     /locus_tag="ACG84X_002551"
     CDS             complement(5393..6316)
                     /locus_tag="ACG84X_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9128365.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6331..6603)
                     /locus_tag="ACG84X_002552"
     CDS             complement(6331..6603)
                     /locus_tag="ACG84X_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128366.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         2046 a         1347 c         1151 g         2171 t
ORIGIN      
        1 gatatatatg caactacaaa taaacgaaga atccttaccg gtatatgaag cattagctag
       61 taaaacaagg atcaagatca tccagctact ttccaaaaaa aagatgaatg tcaaagattt
      121 ggcaaaagaa cttggagtga gcagtgctat cacgacgatg cacgtgaaaa agctagagga
      181 agcaaacatc atcaaaacag aaaaagtagg acaacaaaaa atttcgagcc ttcgtgtcga
      241 taaaatcgat attagttttc cagaaaaaat attcaatgct tttgatacga aagaaacatc
      301 gatacctatt ggtcactata caaattatgc aattgaacca acatgcggtt tagctacgat
      361 ccatgatttt atcgggaaag tggatgaacc acgctatttt atggatcctc gaaggatgga
      421 tgcccgcatt ctctggttta ccagcggatt tgtcgagtat caggcaccta attttttaaa
      481 tacagaggat acattggaga tgttggaagt ttctgtggaa atttcttctg aatttccttt
      541 ttcaaatgac aattggcctt cagatatcac tttcagccta aatggtgtgg agctaggaac
      601 atggacgagc cctggagatt ttgctgatat ccgcggtaaa tatacgcctg attggtatcc
      661 agataatctt aatcaatacg gcttgctgaa gacgatccga attaccaaac acttgacgaa
      721 tatgaatgga gaacccttgt caaacatcac gatcaacgac atccctaaag agcaagacac
      781 ttggcatttg cgaatcgaag tgaaagacga tgccaaacat gtggggggct gtactttatt
      841 tggtaaagga ttcggtaatt acgatcagga tatcaaatta aaagtttact acagctgata
      901 tttttctttt ctattttata aaacaaaaac agccaatccc tatgaaggga cggctgtttt
      961 tgctttattg ttatttccag aaatcatcca aaacggaaat tggcaaatgt cgtttatgtt
     1021 gtgtcttgtt ccaccatgct tcgatttttt cttgtgcttg agcgggaact tcttttcctt
     1081 ctagataatc atcaatttca ttatatgtga cacctagtgc gacttcatct gcaatcattg
     1141 gtttcccatc ttcaagatct gcagtcggaa tttttgtgta taatttttcc ggtgcattca
     1201 atgcttgaag caattgtttc ccttgtcgtt tgtccaaacg gaataatggc aaaatgtcgg
     1261 ctccaccatc accaaatttc gtgaagaatc cagtaatgtt ttctgcagca tgatctgtcc
     1321 ctaatacggc tcctgctctt tctccagcta cggcatattg cgtaatcata cgttgacgtg
     1381 ctttgatatt tcctttgtta aaatcgctga ttcccacacc tgcttcgctt aatacttgta
     1441 cttgtgcatc aacagctggt ttgatattta ctcgcagact aacatcgggc tggataaagt
     1501 caagagcagc ttttgcatct tcttcatctg cttgttcacc ataaggaaga cgaacagcga
     1561 taaattgata gttttcatct tttgtttctt cacgcatttc ttccatcgtt agttgcgcca
     1621 aacggcctgc taaagtagaa tcttggccgc cgctgatacc tagtacaaaa gttttaagaa
     1681 acggatattt tttcaaatat gctttcataa agtcaatact tttacgtatt tcttcttttg
     1741 gatcaattgt tggtttgaca cctaattcat tgataatttc tgtctgcagg ctcatttatt
     1801 ctcctcctat gcttctgtat gaagttctgc tacgcttttt ttcattcgtt ccatgatagc
     1861 cattttatgg ttccagcatt cagtagacag atcgactggg tatttttgcg gattcaagtc
     1921 tcgtttatac tcttcccata gtgaatctag attttctttt gtatattctt tgatttcgtt
     1981 tagtgcaggt aattcgtaaa ctctttttcc ttcgataaag atatcttgta aaactgggcg
     2041 agctgtaaag tctcgaacag ttttattgat aaacgtatgc actggatgga acatgaagat
     2101 agcttcttct tctcgagggt cttcatccca taatgtcacg tagtctcctt cagatttccc
     2161 atcaaaattt cgagtgatgc gccacacttg ttttttccct ggagtagtta ctttttctgc
     2221 attgcttgat aacttgatcg tatccatcat ttttccttca tcatcttcga tcgatactag
     2281 cttgaatact gcaccaaggg ctggctgatc ataggctgtg atcaattttg tcccaacacc
     2341 ccatacatca attttagctt tttgcatctt taaattcaaa atcgttgctt catccaagtc
     2401 attcgaagca tagatttttg cttccgtaaa tccggctgca tctaattgtt cccgaacacg
     2461 cttagatata taggccatat ctccactgtc gatgcgtacg ccttggaagt tgattttgtc
     2521 acctaattct ttcgccacgc gaatcgcact tggcacacct gatttcaacg tatcataagt
     2581 gtcgactaag aacacgcagt ctttatgggt tttagcgtag gccataaatg cttcataatc
     2641 atttccataa gattggacta acgaatgagc atgggtcccg ctagctggta tcccaaatat
     2701 cttcccagca cgtacattgc ttgttgcatc tgctccgccg atatatgccg ctctagttcc
     2761 ccagactgct gcatccagtt cttgtgcccg tctagttcca aattccaata gtggatcttc
     2821 tccgatgaca gatttgatac gagctgcttt tgtcgcgatc aacgtttgga aattgaccat
     2881 attcaacagt gctgtttcta ctaattggca gtgcgctaaa ggcccttcca cttggatcaa
     2941 tggttcattt gcaaaaacta gttctccttc acgagcagaa cgaactgttg ctttaaattc
     3001 aaaattttgt aaatactcca aaaaaccttc aggatagact tctaatccac gcaagtaagc
     3061 aatatcggaa tcattgaacg tcagattctc taaataattg actaaccgtt ccaatcctgc
     3121 aaaaaccgcg tatccgtggt taaaaggcat ttctcgaaag taacattcaa aaacagcatg
     3181 taaatcagct cgacctaatt cccagtatgt ctgcatcata ttgatttgat atagatccgt
     3241 atgcagcgtc aaactgtcgt ctgggtaagt attattcatc ttgtattact cctcttggca
     3301 agttttcatt tcctacccat tataacaaaa aaaattaata ggaaaagaaa tcttccattt
     3361 tttctgaaaa agcacatgtt ttacggatat ttcttgctaa aaatgaactc catctgctaa
     3421 aactatcctt tcttattggt atttaaccta aacgagaaag aatacttatt ttattcaatg
     3481 tatccgagac acgaagaaat tagcgttttc tatttttctt acttgataaa ataagtagat
     3541 tttcctacta caatcgtagc cgttaagata ccgatgattg aacaaatata accaaatgtc
     3601 tctacaacat aatcaatggc aaaagttttt gaagcaataa tacgtctttc cttttttgct
     3661 tcttatcccc aaagaaacgg atataactta ttatgtattg aatttttttg gaaaggcgaa
     3721 ttatgacaag atataccttg cgttgaaaaa actcgcggaa aaaatatcac acgtttttaa
     3781 aaagatacaa agtaagaaag cagctgtcaa tagaatggaa acaaaaatgg cgagacatca
     3841 atcagtctcg ccttgttttt tattgtatac attagatatg gagcaggtta ccataaagat
     3901 gattattagt cgttattaaa tagaatcctt cgtatttttt tgttctatca ctacaatatc
     3961 tttatttgga cgtttgaatt gtattccggc acgttctagc tcctgtttca ctcctacatg
     4021 gactttgaca tcttctcgtg tcatttttaa aacgtgatga atcgcatagt cgatttcttg
     4081 ccttgtgatt tttttcttcg tattgatcat cacgacttgc tttttatcat atgtgtctac
     4141 caatagcagt tgtgttcgat ctaacgaaaa taatttgtaa taattaatag ccgtattccc
     4201 aaaaaagaat tccactactt taggataaaa tgtcttaata tttaaattac tattcacagg
     4261 tgtttcgatt agcttcatct cattcctctt ttctatatag tcgatttaga tccaatctta
     4321 agttatgtta ccatctttcc tagcattaag gaatcggtta caattgaacc tttaaagaca
     4381 aaaggattta ccttttatca cttaatagta taacataatt tcatgagaaa aaaatacaat
     4441 tttttcttga ccatctcgtt acgtaaagga ttatgcttac atttgtcagg aggaaaaata
     4501 atggagtaca caataaagaa aatgtcagag atatcaggag tcagtccgag aaccttgcgc
     4561 ttttatgatg agattggact gctaaaacca gctaggatca attcttcagg ttatcggatt
     4621 tatggcaaaa aagaagtcga tcgtctgcaa cacatcttat tttatcgaac aatggcattc
     4681 aagttggatg atatccaaga ggtcttagac aatccatctt ttgaccacca gaaagcttta
     4741 atcaagcatc agcaaatgtt gctggaaaaa cgggcacaaa tcgataccct cttgacaact
     4801 gtccaacaga cacttgatat gtacgaagga ggaagaaaaa tgagtgacaa agaaaaattt
     4861 gaagggttta aacaacaaaa gttgaaagaa aatgaagaat cctatggaca agagattcga
     4921 caaaaatacg gaaaaaaaaa ggttacagca tccaatgaaa aatggatgaa tatggataaa
     4981 gaaacgtatg aagaaatgca aactgttgaa aagcagatgt tatttgatct cactctttac
     5041 ttaaaagaac cagaagatga aagcttagca gaccgtatct tccaagctca taagaagtgg
     5101 ttatcttaca gctggcctga atatcagcca aaagcgcata aaggactagg aatgatgtac
     5161 gaagccgatg aacggttcac tgcatattat gacgagcgaa gtggtcatgg tgcagcaaaa
     5221 gctttaaatg aaattatcca aaaaaaggcg taatctttta catgatccaa caaaaaagta
     5281 cacgtaaaat gacctaataa caaaacagca gacacccaag ttagattttt atgctaactt
     5341 ttggtgtctg ctccattctt tcacaagttt tttcatccta ctttaaatat attcatcgtt
     5401 gaataaacgt ataaggtatt ttcactttat cctttttttc tgtaagaaac aattgaaatg
     5461 ccatttctcc gcaagcttcc agatggtggt cgatggttgg gaaaccaaga agctcgctga
     5521 tcagcaaatt atcgcgtcca atcaccactg gtgtcttatc ttgcagatag ctttgcaaga
     5581 tgcctgctgc aaccatatcc gaatttgtaa agacaccatc aactccaagc tctttaaaaa
     5641 agaagcctgc ttgttttcct ttctctgcat ctatacaatc ccaaaaaaca agtgattcat
     5701 caaaagatgg aaaaagttga tgacatagct gcaaagtgat ttttgagtta taacttagcc
     5761 tgccacttcg ccccaacgtg atgcccaatt gctttatacc ttgctgcttc aaataagtaa
     5821 gaccttctgt aattgattgt tctcgatcaa taaagacaca gcttgcctgt tttcccttga
     5881 tttcttcaca aaaaactaga ggtccatatt tttgatatgc caataaatca tctagtgtat
     5941 tggcacgaga cgtaatgatc aatccatcga aagctttagc tgcaaattct tcaagatacc
     6001 ttcgctcttt ttctttctga tagcccgtcg gtaaaagtgt cactttgtaa tcataatcaa
     6061 acgctgcttc aatgatccca ctgatcaact gatcaaaata cggatgattg gtataaggca
     6121 gaatcactcc aatgcttttc gtttttccat aacttaactg tctggcattt gcattaggga
     6181 tataatcgac ttctttcatg accgcaagta tttctttcct tttttcctca tctacatatg
     6241 gatgtccatt gattacacgt gaaatagtag aaactgaata acctgtgagc tttgcgatat
     6301 ctcgaatgtt tgccactgct gcttcgccac ctatacaaaa agattttctt gtaaatagtc
     6361 taccacagct ggaccgcatt caaaaaactg atacattttt ccttcatgcg aaaaactgat
     6421 ccgctgcccg ccccaatata tatcttttgt caaattttcg atttcattca ttggtatttc
     6481 ttttactata ttcctattca acccttgaaa actgtacaac gttaatacgg atcccttgaa
     6541 ctcgacaaac gcataaaaat aattgttcgt tgtgccatct gttatctcta cataagtatt
     6601 cattgcaagc cctccttttg atactttgag tatagtgtat gaaacgcgtc tcatagcaag
     6661 gagtttgttt tgccaaagaa aagttttatt cctctttcat tattaccaaa gtctc
//
LOCUS       DAZKCH010000111         6644 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000111 DAZKCH010000000
VERSION     DAZKCH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.114"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..859)
                     /locus_tag="ACG84X_002553"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="ACG84X_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa10 family transposase"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="ACG84X_002554"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="ACG84X_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFP9128367.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="ACG84X_002555"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="ACG84X_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="ACG84X_002556"
     CDS             complement(2143..2373)
                     /locus_tag="ACG84X_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HFP9128368.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="ACG84X_002557"
     CDS             complement(2603..3421)
                     /locus_tag="ACG84X_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9128369.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="ACG84X_002558"
     CDS             3582..4271
                     /locus_tag="ACG84X_002558"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFP9128370.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="ACG84X_002559"
     CDS             4285..5787
                     /locus_tag="ACG84X_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9128371.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="ACG84X_002560"
     CDS             5800..6276
                     /locus_tag="ACG84X_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFP9128372.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="ACG84X_002561"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="ACG84X_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2174 a         1032 c         1203 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttattatcca aaaataataa aaaattggag cgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt catgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DAZKCH010000112         6353 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000112 DAZKCH010000000
VERSION     DAZKCH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6353
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.115"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..835)
                     /locus_tag="ACG84X_002562"
     CDS             complement(<1..835)
                     /locus_tag="ACG84X_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128373.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VY"
     gene            complement(1043..1969)
                     /gene="glsA"
                     /locus_tag="ACG84X_002563"
     CDS             complement(1043..1969)
                     /gene="glsA"
                     /locus_tag="ACG84X_002563"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFP9128374.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(1992..3419)
                     /locus_tag="ACG84X_002564"
     CDS             complement(1992..3419)
                     /locus_tag="ACG84X_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9128375.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(3450..4664)
                     /locus_tag="ACG84X_002565"
     CDS             complement(3450..4664)
                     /locus_tag="ACG84X_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFP9128376.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            5014..6093
                     /locus_tag="ACG84X_002566"
     CDS             5014..6093
                     /locus_tag="ACG84X_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9128377.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
BASE COUNT         1941 a         1401 c         1226 g         1785 t
ORIGIN      
        1 tataaacaac ttcgaaatct tttcttaaca gctccatgtt ctcattggta taatttctac
       61 tgttgaacaa agaaaaaata taatagacat cttcttcttg taagtctaga attccttttt
      121 gctcttccaa tccttgacag actaattgaa ataacggctt cgtttctgcg cttttcttat
      181 cttcttcttt cagtccaagg ggaaatgcct ttcttccgat tgcgatctct attcctcgta
      241 tgataaagga cttttcatct tccgaatatc ttcttttaaa aaaatgagtc tctacataat
      301 caatcaactc gttacaagct tcttctacat acggattttt attttcatag ccttcccaat
      361 tgacataacg tactaaagct agcaagatgt tccgcgagtc aaattctggg ataatgattt
      421 ctttattttt caaataatca ttttctttaa aaaaatccaa tacgattttt ttgattgtat
      481 atactttgct caaagaaata aattcaagat cagccagttc tgtactcgtg aatataccat
      541 taaaataata acttaaaaac tttaaaaaat aagattgacc gtacagaaac tgtgtgagct
      601 cagaaagagc aataccatgt ttgaatacga gtttatactt atgcttctct cttacttgtt
      661 cttttataca atattctaga cactcggcta gactttctag atcgtgaagg atcgttggtg
      721 tagtcaccct tagagaaata gctgtttgtt cgatgtctat ttcttggaat tcaaataatt
      781 gttcacacag atacactttt ctaaatatat ttcgctcgat gtaattttcc agcattcctg
      841 atacacgcct ccagtttttc ttatgatttt atttaatcat atctgtaaat cgtatttttg
      901 tttccttttt atttagaaaa gccctttcaa aaaccaataa aaaaagaaac tgggacaaaa
      961 gtcaaacaag ctcacaattt cagcctcatt gtaggtagct ttgagccgtt tggactttta
     1021 ccccagcctc tttcaagaat ggttattcaa agatgtcagc gtctagttct ttgactacat
     1081 ctttcaacaa ttggatacca gctgcgctgt taccaaatgg atctagtgcc gggctgaaga
     1141 cacctatgcc gtaacgattt ggcacagctg ccatcaaccc gccgcctaca ccgctttttg
     1201 caggtacacc aacatggacg gaaaactctc ctgattcatc atacaaacca gcagttgtca
     1261 taattgattt gacgattgta gcactttctt cagtaatgat ttgtttgcca ttccaaggag
     1321 caattccttt atttgccagc acagcagcta attttgctat gcctgtagcg gtgacattga
     1381 gggagcattg tctgaaataa gcatcgagta tctccggtac gtctccttcg atcatttgat
     1441 tacctttcat atagtaagca agagagcgat tgatatcacc tgttcttgat tcagaatgat
     1501 agatttcttc attcaatgtg atattaggat catcacagat ctctttcata aatgacaaga
     1561 ttcgctcaaa tttttcatct gcatctttac cggcaatcaa cgaggttgtt gcaatcgctc
     1621 ctgcattaac aaaaggattc attggatgtt tgcgatgatt gatttccata ttcatgatag
     1681 aattgaaggc aaaaccggtt ggttccgtgt tgattgtttg aaagactttt tctattccgt
     1741 tgtctttgat tgctaataac aatacgggaa cttttgacat gctttcgatg gcaaagcgca
     1801 catcggcgtc tcctccctca atcagttgtt ttgtatccaa atcataaatc gccataccta
     1861 attgtttggg atccacttca gctaatgctg gaatgtaatc cgccacttgt cctgtttgat
     1921 aatagtggaa attttttcca atcaattgtt ctaattcttt tacttccatt tgaataacca
     1981 gctttcattt tttatttttc tgcatgctgg aatttatgac ggcatgcgta gatcgtaaat
     2041 ggaataacta agacgataag ataagaaaca atcagaatcg tttcataaat cccatgctgt
     2101 ccagctgcga tactagcagg tggaacaaat gagatacaaa aagcaaaaag tgaagtcaaa
     2161 agacctaaac aagcaacgat tacttttaca acttttccgc ctggaacctg ataggctctt
     2221 tcaagactgt catctttaaa aaccagcttc aaatagcccg cgaaaaacat aaagtacaac
     2281 atcaggtaga ttacaacagt caatgacatc gctgcaagaa atgaaagatt attccccccg
     2341 ccgcttaatg taaagacggc tgcccagatt gttgcaacga tcccatttgc gatcatcaaa
     2401 tgagcaggaa caccgtgtgt gttttctttt gcaaaatatt caggaagtaa tccttcttct
     2461 gctgctacgt gaagtgcttt tgaaggagag gttacccaag aagcaatttc tccgatgaca
     2521 cctaaacaaa caagaatcgc aagaattttc gcaatccatg caagatttgg atcaatgtgt
     2581 cttaatagga attctaacga ttgaatcacc cctgtattaa gagacaaacc atgttgaggt
     2641 actgtagtag cgacggtcaa tccgccaaaa gtatctaaaa tgattgccag aataaccaat
     2701 acaaacattg ctaatggata atccttttta gggttttcca tttcatttgc atgactggca
     2761 gatgtttcta cgcccatata tgctaaaata aaggaaacaa aaacaaccag cgtaggcaat
     2821 ttcgaaaaat caggaatcaa tgttttcata gacagtatcg tttgtagtgg agcgcctgaa
     2881 gcgacataat ggatccctaa gccaaacaag actaatgctg gcaacaagat accagctaca
     2941 aaaccgatcc gagcaatcaa tgaagtgtat ttggttcctt ttaactgtga gagtaaaata
     3001 gcccagaaaa taatcaatag gattgccaat ttcagatatt tattgttttg tatagcacca
     3061 atacccgttg cataggataa tgcaccagtt aagaaataca gcatggtcaa gtagccaact
     3121 gttatctcaa accattggaa aaagattgcg gcaaaaccga atcgttttcc caatgtgcga
     3181 ctgacccaag tatagacacc gcctttttcc catcctttca ccgttgccat ctctgctgcg
     3241 cacaatgcca cagggataaa ccatagcaaa ccgcctaata acaagaaaaa tactaagctg
     3301 aagcctgagg tcgcgaatgt gggatattca tataatgaaa cgaccattga gatggtcata
     3361 gccaaaaagc caaagaacgt taattttttt gcaggaattt tcgttttgct ttgttgcatg
     3421 aatcttcctc ttttctattt gaatttgttt caattgagtt tgttgccaaa gaagaaaaag
     3481 tccaatcctt cttcttgttc ttcttttgta gtagtgatcg ttgtaaagtg catcgccgat
     3541 tttaaaatca ctgttgtcag cacataggca tacacggcag taatgatgac accaatcact
     3601 tgaatcccta agaagtacca gctgcttgga ttcgttagta aatggctgtt agatgcaaag
     3661 atccctatca gaatcgtacc tgtgaatccg cccatgccat gaacacccca cacatcaagt
     3721 gcatcatccc attgtttctt tttacgaaaa tcaacagcag catgacagac gatacccgca
     3781 atgatcccaa tcagcatggc actttttgct tctacataac cggcacaagg cgtaatggct
     3841 gccaatccag caacggatcc tgttagtacg tcgacaaaat caaagccatt tccttttact
     3901 tttgcaatga tcagccaagt aatcatcgca aatgcaagag cgatgaatgt tgaaccaaat
     3961 gcattgactg cttgttcatc tgctcgaagt gcaccaccgg aattaaaacc gaaccagcca
     4021 aaccaaagca gtcctgtacc gatagcagct gccataagac tgctatgctg acttctttct
     4081 cctaaaggaa tctttctttg accaagtgtg aggatacatg ctaaagagcc gaatccagct
     4141 gtcgtgtgga tgactgctcc accagcgaaa tctctaaatc ccatctgatc caaaaatccg
     4201 ccaccccata tccagtggca aacagggaaa taaatcagca gattccaaaa aataacaagt
     4261 ataatatagc cttttaaatt caatctccct gcaaaagctc ctgtcatcaa aggaacggta
     4321 atcacgataa acatcagttg gtaaagaaag aacattaaaa atggaatcgt tgcaccatga
     4381 aacatgttgg ggaagcttgt aacatgtctc atcaaaaaga aatctgccgg gtttccaata
     4441 acaccgccga tatcccgtcc aaaggccaat ccgaatccac caaataccca cataatcgtt
     4501 gttatcccaa cggagagaaa agattgagac atgatcgtta gtatattatt cttccgtgct
     4561 aatccgccgt aaaaaaaagc tagaccagga gtcatcaggc aaaccattgc tgtacataaa
     4621 atcatgaatg ctgtatctcc tgtattgata ggtaatgtat tcattttttt cgcctccttt
     4681 ctacgattac gagtataaaa gaaggtgtag ttgttttttt cttctgtttt tttgaattaa
     4741 tacttgcatt tataaaagac agacaattaa taaaagcttg atgtgttgtg ctctttttcg
     4801 tttttcacac aaataaagac aaaaaataaa cggtcttctt tttatagaaa accgtttatt
     4861 ttcgtctttt tttattttta aagatatttt ttcataagga ataaagaggc ggattttata
     4921 attaacttag ccatttggaa ataaaaaaac gccacgtgaa ttccatgtta tattgaagtt
     4981 accacaactc tcaatagaca aggatgaatt cacatgacgc aaaaccatga taacacagtt
     5041 tcacgcaagg gaaaacacct aacctactca gaacgttgcc aaatcgccat cctgaaaaag
     5101 gaaaactatt ccaaccgtca ggttgcggat gtcctgggct gcgtgccgca gaccataaac
     5161 aacgaaatca aacgcgggac cgttactcag cttaaccgcc agaatcagaa cgggaaggtc
     5221 tacgactatt atcatgacgt ctacgacgcc gatgccgggc aggcggccta cgagaagaac
     5281 cgcttgaact gcggcagacg gcccttatgg gccgacacgg acgccttcat tgaatgggcg
     5341 gacgacatga tgctgttgga aaaatggtcc ccggacgtgg tggtgggctt tgccagaaaa
     5401 cacgaattgt tcgacccggc cattatccct gggaccacca ccctctatca gtggatcgac
     5461 cgtggcatca tgaaaacgaa gaatatggac ctgctagaaa aactgtcccg caaaccgaaa
     5521 tcgtcccgtc atggcaaccg cccgaataaa cgggtgctag ggaaatccat tgaagagcgc
     5581 ccggaggcgg ttggtacccg gaaaaccttc ggccattggg aagtcgacac ggtcgtagga
     5641 aacaagacca agtcggatgc cgtgctgctg acgttggtgg aacggcagac acgcttcgag
     5701 gtcattctga agctggccgg gaaggatgcc gaatcggtca accaagcggt ccgacagctg
     5761 agagaacggg ctggtgcgta cttcggccag ctgttcaaga cggttacctc ggacaacggc
     5821 tcggagttcg cgggactgca cgatgccttg caggatgtgg caaacatcta cttcagccac
     5881 ccctatgctt cctgggagcg cgggacgagc gaaaaccaac acaagctgat tcgccgtttc
     5941 atccccaagg gcagcccaat cggcaacgtg agcgaaaacc aaatcttgcg gattcagcgt
     6001 tggatgaacg attacccgcg aaagattttg ggctatgcaa cgccgcatga cacgttcgtc
     6061 caggcattta ggcaggaacg gttgacggct tgacacgtgg gcccttgaca acgagcctcc
     6121 ctcggcatgg cttgtgtctg gaaagctggc cggggccagc cagtcgggag actaccatgc
     6181 ctcagctcat tgtcaagggc ccactcgatt agaaaaatta gacggttggt ggtaacgagc
     6241 aaccgggtca ccatgggtgg ctaacttaaa cttgaaattt acgtaaggaa taaagaatac
     6301 ttcatataaa atatataaaa aagaaccgca gcgagtgtcg ctacggttct caa
//
LOCUS       DAZKCH010000113         6189 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000113 DAZKCH010000000
VERSION     DAZKCH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.116"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            124..1239
                     /locus_tag="ACG84X_002567"
     CDS             124..1239
                     /locus_tag="ACG84X_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128378.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(1265..1705)
                     /locus_tag="ACG84X_002568"
     CDS             complement(1265..1705)
                     /locus_tag="ACG84X_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFP9128379.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            1865..2371
                     /locus_tag="ACG84X_002569"
     CDS             1865..2371
                     /locus_tag="ACG84X_002569"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFP9128380.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            2539..4452
                     /locus_tag="ACG84X_002570"
     CDS             2539..4452
                     /locus_tag="ACG84X_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9128381.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            4457..5458
                     /locus_tag="ACG84X_002571"
     CDS             4457..5458
                     /locus_tag="ACG84X_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9128382.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(5660..5866)
                     /locus_tag="ACG84X_002572"
     CDS             complement(5660..5866)
                     /locus_tag="ACG84X_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFP9128383.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
BASE COUNT         2290 a          944 c         1220 g         1735 t
ORIGIN      
        1 gattggttat attttactgg attcacttta caaaggtact tatcaatcct tagaaaatct
       61 tagtcaaaaa attatataag tttgcgtacg attcaaagaa aattaagaga acttaatact
      121 attttgaaaa actatcattt atcttgcagc ttgaaaaaag gtaatccgat agaaggagaa
      181 gaataccgta tccgatactt ttttcacttg atgtattggc agtcattcga cgaaaatcat
      241 tctgatatat tatcaagtat aaaaaataaa cgtcaactat tagaaaaatt tgcgaaacat
      301 gcgccatata cgcgtagtat agatagaaag aaatggatca gcctactaag aatttcgttg
      361 caacgaatga aacaaggcca ctcgattacg tatgtcccag aagagatgaa caaatttgtg
      421 catccattga taacaaaaga agagtttacg cattacatac tagagccttt ttttgaagca
      481 aacttctggt cgatgaatca catcactcca acagagcaag cttaccttta ttttatgttt
      541 ggtgtaatga acacctattt ggaagaagat ttgttggata ctccagataa agtacaagaa
      601 agttggggct ggattgaatc gtctattgta gaaaattttg aaaaaaactt caagatttgt
      661 tttacaactt cagaaaaaaa ttatctatat gtcaatttgg caatgatcca tttgtattca
      721 agggtttttg ggacaaaaaa gaaggtggat gcttttggaa aatcagcaga agacagagat
      781 tttcagcata tatttccagt gatgtatcca atcatgcaac agttttttag tggggtagct
      841 cgcagaattc cagagcttaa tacttattat gaaaagaaca gacggttgat ttttcaatac
      901 tgtatgttag tcagggatat ttttataaaa cacgaacaac ctgtcatatt ctatattcaa
      961 tcaaagtatg gtaaaacaca ggaattatgg gcaaagaaaa ggatattatc tatgactgaa
     1021 cgcccaataa aatatagtgc atccgctgat cagttacctg atattgtcat tagcgattat
     1081 cctatcgaca aaaaggcata tgatcaaacg aatacacaga tattttactg gaatggacaa
     1141 cctacaaaaa atgattgggc gcgtctgaaa gctgaaatca taaaaatcag gaatgagaaa
     1201 aatagatcca tattggaaaa attggatttc gttaattaag aaaagcagat tgtttatgcc
     1261 aaaattaaga cattgcaaaa agattatttt ctttaaaatc gacaagatga ccagaaagca
     1321 agagttcgtt gagctcttgc tttcttttag ttttagaaag gaacatcctg attttatctt
     1381 cgctaaatcc agtcaaaagt tttgcagatt ggtcgtagat aatcggtttt ttcaataaag
     1441 aaggggatgt acgaatctca atatatagtt cactcaaact gagttcatct attctgtgaa
     1501 caagattttt ataactaata gaatgagtag agagcatttc ggtcacgccg ttgtttgtca
     1561 attttagtaa gtggataaat tcatttttgg ttagtggttg acgaattaag ttctgttcga
     1621 taaacggtat atcatggacg ataagccaac gttttgcgcg tcttgaagac gagcagccag
     1681 aacctgtata caatttaatc atcatacatt cctccaatag ctaagtattt atgaaataat
     1741 aacatgaaga aatagtcgaa aagtgccatt tagaggtgta aaataagaaa atgttgtcac
     1801 gtataatgga actagctaga taagaaatac tattaaatca agaaaaaaga aagaaggcac
     1861 aagtatgtca aacacagccg acgcaatagt agtgatcgat ttacaaaaag gggtatgttt
     1921 tgattcttcg ccgatacacg aattagaaac agtgacagca ttagtgaata aaagaatcaa
     1981 aacatacgaa acgattggga aaccagttat tttcgttcaa cacgaagatg ctcaattagt
     2041 gccacaaaca aaaccatggg agctattgtc ggaattatct attcctgagc acagttattt
     2101 tgtgagaaaa acccatgcga attcatttta taagactaat ttgagtgttt tattaactga
     2161 attggactgt cattcgatcg aattatgtgg ggcacaagca gagtattgta tagatacgac
     2221 tgtgaagttt gctcatggat taggatacca gcttatgatg tgtagaggag caacgacaac
     2281 ttatgataat ccttttatga aagcaaagga aacaatcgct ttttacgaga aaatttggga
     2341 taaacgattt ctgacatttt tggagcaata agttgtttct tcgtttaaaa aaagcagaat
     2401 ggatactggt ttatccattc tgctttatta cgtaaaatga gaaaataatc ctgttctatt
     2461 tttatgggat aaaccattta ttttttgtat aaaaaatgtt tgcgtttaca tataattctc
     2521 ctagaaacat aaaaaggagt gaatagcttg agaacaaaac aagtattaaa gggagcgttg
     2581 gtcatcttat ttgctgtaag tacaagcgtc ccgcaatgga cagtatatgg agagagcatt
     2641 tcttccgaat cggaatctcg ggaggtagaa accacagaaa ctactgatgc tggaaatgaa
     2701 acgaaatcga gtacttcaca aacagaaaca aatactgaaa caacggttga gacatctgtt
     2761 actagcacag atcaagaaac gaccgctacc acagataacc aacaaacaga agaagcaaca
     2821 gctacaaaaa tgtcaaacga cgaatcctct tctgctaaag taagtgacaa agagaatggg
     2881 acagaaaatg atgatatcgg taaaggtgaa aatttcaatg gtaaagaata tttgaattac
     2941 ttcggtaaac agatgacaga aatacttaat ggaccaacag aagacatcaa gtcaaaatta
     3001 atagagttat tagtcactga gcttgctgtt aatgattatg gtgtagataa agagattatc
     3061 aaacatctga ttgctactta tctattgtac gatatcgctt ttgcaaaaaa cagtgtgttg
     3121 atgtcgatgc ttggaggtac agatgatggg acaacgccta cagaaaacac aggcttctat
     3181 ccaaatacaa aacaacttca tcaaactgta ctaaacaaac aagatggcaa aatgatggat
     3241 gtatatgcat attatgtcga tcaaggttca gataaaacag tcatgatcca tggcggattt
     3301 cgagggaatt ggaataacgg gatcgttaca gaagaataca atgattttta taaggccggg
     3361 tataatttat tatttgttga ttccagagcg actggtaata gcggaggcga ttatgtgacc
     3421 tatggacaat atgagtcaga tgacgtcctt tactggataa atcaagaagt tcgagagcgg
     3481 ccatctcaaa agattttact ttatggtggt tcgatgggag cagctacgat gatgtctgta
     3541 ttagcgaaag atattcctgt caatgtcaaa ggaattattg aaaattgcgg atttgcatca
     3601 attgatgaac aactacgttt tacgtacagc cagacagtag cccccgcact accggatgcc
     3661 ataaaaaatc agttagacat cattggggat caagagcatg aagatttatt tatgggcctt
     3721 ttgaaacaat actattttga tcaggagatg catttggata caaaagctgc tctacctacg
     3781 attggaatgt cagattcatt gcctaaattg attatccatg gaacagcaga tgatgtagta
     3841 cctgtgtcta acgcgcaaaa attatatgag ttatcaggag ggtataaaga tcttttatta
     3901 gtagaaggag cagggcatgg aaaggcacag gaagttgacc atgctgccta cacgaaacat
     3961 gtaacggact ttttgaaagt agtgttccat gatcagataa acgtaaagta tgtggatgaa
     4021 aacaataaaa gtctactcaa agaccaggac gaaatccagc tttacggagc ttatggagaa
     4081 aattatatga cagagcaaaa gacattcgaa ggatacgaat tagcaaatgt tgaaggaccg
     4141 actgaaggga tttttaatga gacgatacca actattattt tctattacaa aaaaatccca
     4201 gtagctccac caaaaaagca agatccgaca gagaatgcag acaataaggg aaagaatgaa
     4261 cctcgagagg atcaatcaag tgatgatacg caaccgattc agatgacagt gaaagtacaa
     4321 aaaaagacag atgcaaaaaa aagaatgttg ccgaaaactg gagaaaagaa acattcgctt
     4381 ctcatttatt caggtggatt tttatctgtt agcacgatta tcacatggat ttggcgaaga
     4441 aagagagggt aaatgaatga aatggttcaa gcgaatagtg attgcagtac cagttatcat
     4501 cgtagttatt ttagtcactg tatttttgat taatcaaatc acaccaaagc cgattagctt
     4561 gcttgttaga aaacaatttg acacaagtga aaaagaacaa gtatatgccc gaccagatga
     4621 tttccagcaa aaaatcgaac aaatcgatat aaaaaaagaa atatcctatc cttcaaagta
     4681 caaaaataat aatatggata tctacacacc gaaagtggaa aagaaaaaat taccgattct
     4741 tttctggatg catggaggcg catatgtagg aggggataaa aatgattgtc gtgattattt
     4801 ggaatatcta tgttcagaca cgcagcaaat catcgtaaat atagattatg aacgatcacc
     4861 ggaagcaaaa catcctacac cagttatcca attgaacgaa gccattcaag cagctaaaaa
     4921 agagataaaa gatcaagcag attggtcgaa tatttcgatt ggtggaaatt cggcaggtgc
     4981 acaaattagt ggagaatatt tgttagcact tcaaaatgaa gaaattaaaa aagctgatca
     5041 tcttgatccg actttggaga acaagcagat tacgaagttt atttctttgt ctggtctgtt
     5101 ggatccttct gcacttactc aagtaagtga taaaatctct agctttcttt atgaaaaatg
     5161 tggatgggct tactttgata ataaggactt tgaacaatca gagaaggtca aaagtttagc
     5221 cttggtcaga catgcggatc gttggacgca aaacacattc ttaacggatg gaaatacaaa
     5281 tacgtttacg aaacaaatgg aagaagtaac ttctgtattt gagaaagcgg gggtgaaagt
     5341 cacaaaagta gattatgcgg agaaaaatgc tgttttgaac catgaatatc agtttgattt
     5401 cagcaataaa caagcgcaag aaacatatca aaagttagta atgtttttca aggagtaaag
     5461 tcttatgatg caaaagaggt tgtaatctgt cacttagctc caagtcacaa ggagcaattt
     5521 caataaacaa gcttttcatg gtttatgaat attgtaactt gtgactgagg agttagagat
     5581 ggcaaggggc accttttatt cgaaatttgg gaatatcaca cgattattgt cacgatctct
     5641 tttacgtaaa ttttataagt cagatttgtt gttttgatcg tttaaaaaaa gcaacaaatc
     5701 cgaagcctgc ggaggcaaga agggacaaaa agccgagtgg taagcaaaag aatgctggtt
     5761 ccactaatat tccgttgtta ttgatataag gctgggaaca aagatgaata gcaaataaaa
     5821 tcaatgcact agcgaaaaaa agcaaagaaa tatggatagc tttcataagc agcacctcct
     5881 tttttataat tgtatgataa atagattaag aatctataaa tgtgacaagt ttgttaggat
     5941 gtgaataaaa tgatcatcta gcgaacttga aacaaagatg gctaatgata agcaattaat
     6001 gattcagcaa tcagataggt acaaagttta ccatcatacg tctagaccaa taatagaaaa
     6061 tatgggaata taatagaaaa gatttaggat acccccaaaa gaatttcccc aaaaattcga
     6121 tgtatcctaa acttttttat tttacataac aatcatatca actgtgaaat aaaattacaa
     6181 atgataacc
//
LOCUS       DAZKCH010000114         6173 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000114 DAZKCH010000000
VERSION     DAZKCH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.117"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            725..811
                     /locus_tag="ACG84X_002573"
     CDS             725..811
                     /locus_tag="ACG84X_002573"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFP9128384.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACG84X_002574"
     CDS             complement(932..1621)
                     /locus_tag="ACG84X_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128385.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="ACG84X_002575"
     CDS             complement(1866..2780)
                     /locus_tag="ACG84X_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFP9128386.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACG84X_002576"
     CDS             complement(2762..3142)
                     /locus_tag="ACG84X_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFP9128387.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACG84X_002577"
     CDS             complement(3592..3879)
                     /locus_tag="ACG84X_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFP9128388.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACG84X_002578"
     CDS             complement(3899..4123)
                     /locus_tag="ACG84X_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFP9128389.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="ACG84X_002579"
     CDS             complement(4578..4748)
                     /locus_tag="ACG84X_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128390.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="ACG84X_002580"
     CDS             complement(4763..5296)
                     /locus_tag="ACG84X_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFP9128391.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..>6173)
                     /locus_tag="ACG84X_002581"
     CDS             complement(5317..>6173)
                     /locus_tag="ACG84X_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFP9128392.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAZKCH010000115         5769 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000115 DAZKCH010000000
VERSION     DAZKCH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.118"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..300)
                     /locus_tag="ACG84X_002582"
     CDS             complement(<1..300)
                     /locus_tag="ACG84X_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFP9128393.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACG84X_002583"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACG84X_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACG84X_002584"
     CDS             complement(1014..1304)
                     /locus_tag="ACG84X_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128394.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="ACG84X_002585"
     CDS             1706..1942
                     /locus_tag="ACG84X_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128395.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="ACG84X_002586"
     CDS             1949..3901
                     /locus_tag="ACG84X_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFP9128396.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="ACG84X_002587"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="ACG84X_002587"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFP9128397.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="ACG84X_002588"
     CDS             complement(4797..5489)
                     /locus_tag="ACG84X_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFP9128398.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1894 a          996 c          917 g         1962 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttcaagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca tatgtaattt
     5581 taatataaat actatcaaat actcatttaa tcctcctttt ttatctattt aaaaaatctt
     5641 ttttatagag aaaaatgcag gttaatactt tcttaaataa atatttatgg tgaacaaaaa
     5701 caaaaaagca agttttatta aacgtaaccc ttttcatttc atagattact gtatttatta
     5761 caaaaaacg
//
LOCUS       DAZKCH010000116         5689 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000116 DAZKCH010000000
VERSION     DAZKCH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.119"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(488..1297)
                     /locus_tag="ACG84X_002589"
     CDS             complement(488..1297)
                     /locus_tag="ACG84X_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9128399.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="ACG84X_002590"
     CDS             complement(1297..2043)
                     /locus_tag="ACG84X_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFP9128400.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="ACG84X_002591"
     CDS             complement(2061..2528)
                     /locus_tag="ACG84X_002591"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9128401.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="ACG84X_002592"
     CDS             complement(2528..2938)
                     /locus_tag="ACG84X_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9128402.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="ACG84X_002593"
     CDS             complement(2949..3962)
                     /locus_tag="ACG84X_002593"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9128403.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="ACG84X_002594"
     CDS             4179..4913
                     /locus_tag="ACG84X_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9128404.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="ACG84X_002595"
     CDS             4897..5607
                     /locus_tag="ACG84X_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9128405.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          943 g         1719 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAZKCH010000117         5685 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000117 DAZKCH010000000
VERSION     DAZKCH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.120"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1128)
                     /locus_tag="ACG84X_002596"
     CDS             complement(<1..1128)
                     /locus_tag="ACG84X_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFP9128406.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
     gene            complement(1164..1874)
                     /locus_tag="ACG84X_002597"
     CDS             complement(1164..1874)
                     /locus_tag="ACG84X_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9128407.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            complement(1942..2757)
                     /locus_tag="ACG84X_002598"
     CDS             complement(1942..2757)
                     /locus_tag="ACG84X_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HFP9128408.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            complement(2768..3736)
                     /locus_tag="ACG84X_002599"
     CDS             complement(2768..3736)
                     /locus_tag="ACG84X_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9128409.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            4499..>5685
                     /locus_tag="ACG84X_002600"
     CDS             4499..>5685
                     /locus_tag="ACG84X_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9128410.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LEC"
BASE COUNT         1746 a         1168 c          908 g         1863 t
ORIGIN      
        1 attttttata acagttgaca tgtaagcctc ttctaacgtt tgattcaagc cgagaatttg
       61 tggatatacc tctgctacta cttgtccttc gttcattttt tctgctgtct tttgagtaac
      121 catttccaaa tcactaatcg aattaaaaac gccttcaggt aaccgctttc caaattcgac
      181 aagaattgac gcagctttat aacccgcttt atctccttcc gttgtcaaac agcaaggaat
      241 ctctacttca ttgaatgcag caacttctgc tttaattgcc tcatagtcaa tctcgggtga
      301 agctactcct gactgataaa caccgtaaat atctccactt ctatccgcaa caacaccatc
      361 taccatgatc ttcactccac caaagcggac cttttcaggg aaaacttttt ccttatactc
      421 atatagaagt tcatgctgta gaggttcttg gactgcctgc acatataggt tactaagtat
      481 tttcctctga ggtatattag aaagaaattc tgcgtcatca aaaacgattt ctttcattga
      541 tataacacct tttgaaagca gtaatgcttc aaattcagcg taaacctctg ctaaaagctt
      601 tttgtttgct agcatttcct taattaataa tactcgactt tcagcactgg tttctttttc
      661 tgtaaaacca taagtctgct tagcaatagc attcatccaa caatggctgc gatttttgtc
      721 gatcgctgtg attggaccaa agtggtttat ttcattcaat agctcttctg atgggtcagt
      781 tttccacagg gcagcatccc agccatgagc ataaattggt tcatctgctt ttttatggtt
      841 cattacagct ttaatacgct ctacagcctc gttagctgaa gatgtatcgc ttaaatctat
      901 gccagcattc atagccaaat aaccactgaa aaatacatga ttatcatgaa ttgctggcat
      961 aacgaattga tcatcataag caattaattc cgtgttttca tttaatagat cactgtaatt
     1021 ccagttgttt tccacctttt caatgatccc ttcattgatt acaatataac ctttgaaagg
     1081 tggctgctct ccatcaaaaa tcatttttga ccgcaatatt tgcttcataa ataaaatcta
     1141 ctccttgaaa tccaaacagg aaatcataag taaaaacgat atacttctcc caggtaatat
     1201 tgattaccta catgaattgg tatgttgttt tgatcgttga ttaaagtatc cataaagaaa
     1261 aagggcgtcc caacagctac ttccattatt ttggcaattt ggtcatcagc tgtgacaatt
     1321 tcaagtgcag tttccccagg attgatggct aaggtacctt ggactttaag tacttcatac
     1381 aaagaatcag tcagctcttc ctccattaag aaactatatc tttcataaga aaaataattg
     1441 ttttctaaca taatggggat gttatccgcc attcgctttc tctggatata taaaacatca
     1501 tcaccttgag cgatatcgag tttttttgcc atcccttcag ttgctggaat gatcttgcgt
     1561 tccaaaacaa tgctagtcgg tgtaaaacca ttagatttac aactctcact gaaacccata
     1621 atatattcaa ttttacgaaa aactttatgc cggttgacaa aagttccttt cccttgtttt
     1681 ttaagtaggt acccttcttc taccagttct tctactgctt ttctcactgt gattcggctg
     1741 acctcataac tttctatcag ctctgattca gcgggaattt tcgtattctc gggatactcc
     1801 cctgtattga ttttattttt taatatttct tttaattgta agtacaatgg taattgtgca
     1861 tttgtatcca gcattttttt aacctccact ttaccgggat ttctttcttt aggttatcaa
     1921 atgcaggaat ttaaaacaag ctcaatcgta atgaatacca aagccgaacg aaccgtcaac
     1981 cagacaagac ttcccagcaa attcattccc ctttttcatc gcggtgacta tatcgtcccc
     2041 ttcgagaaaa taaagtagga aagctgttaa gaaagaatct cccgctgcca ttgtatcaac
     2101 tggttcttct agcacggggt tcacttcata aaactttgct ccatcataac caatagccgt
     2161 tttttctcct cgggttgcaa tcaatacatc atttcgctca caaaaatgct tcatcaaaaa
     2221 ctgctttact tcttcatcgg aaaagtcttc tatagaaaag aagccaaaat caactttatc
     2281 aattgcccgc tgaacctctt cttccgtaaa gtcgtcagaa aaatcataag aaatctttcc
     2341 agaaacattt tgtaactctt ctaatagatg attgacatgg ctatataatc ccatatgaat
     2401 caattcaaac tggtttaaat attctctgtc ttcttcagta agctgaatcg ggtattcacg
     2461 agtaacacct cccgaattgc tgccaaggaa aatccggtcg ccctcatcaa tcttcactct
     2521 ggcacagcca ttctcgcctt tttcaaagcg agagtgactg ttgtccagtc ctatttcttt
     2581 tattgctgat aaaacatgag ctgcctcctc atctgagcca aaaactccca taaagctact
     2641 ttcatgtccc agtttttttg caaaaactgc aaaattcaat gaatttcctc caggatacat
     2701 aattcccaga ttttcatatt tatcgacgac gttatcacct aagcctaata ccttcatttt
     2761 aatcctccta gtactccact ttccccatat agcgacgaac atctaaatca tgattgcgta
     2821 catctgctaa agctgaacga tattctgaaa gaatactgta gaataaaatg ggattgaaga
     2881 attcagaaac ttcatctgat atcatatcca atcctagttc ctttgcatca acgatttcta
     2941 ctctttctgc atatttatca aggaatcgtt ttgcccgttc atctaaagca cgagtgcgtc
     3001 caatgctcat caagagaata aaattcgtat ctttgtctgt tacttcaaaa ggtccatgga
     3061 agaattctcc agaatgaaca gaagttgaat caagccattg catttccatc aaagagcaaa
     3121 ttgaaaaacc ataagcatgt ccatatgatg gtccactacc taagatataa aacattgttt
     3181 catctttgta cttatcagca aacactttaa tacgatcctg cacctgctta atgccatttt
     3241 caattacggt atcgataacc ttcatgcctt ctctgaattt accgtaatgt tcaaatgttt
     3301 cggtaacatt gaccaaagat acagttaaat caagaatgat ggccatagga ttattgacta
     3361 tttttgcatc atctccccat tcgtaaagga aactatgatc agaaaccttt aataaatccg
     3421 cagttttatt atgagtcaga ccaacagtca cagctcctct agcttgagcg acttctcctg
     3481 cttttaccgt ttctgctgta tttcctccat gagaacatag aatgacaaca gatttatcat
     3541 ctaattgctt tggggttaca tggttaaatt cgttcgctgt atataagcct gtaatacact
     3601 tcgatgcttc ggctttaaga aaataatctg agacatacat atctaccagc gaaccgccac
     3661 aagccaccaa ataaattcca gaaatctctc catcattttt ttctacaatt gcgttaaccg
     3721 tttttgctac atccatcaac atttcctcct taaaatttta aaaatgttaa ttttatccaa
     3781 aataaaagta actgattaaa tgtaaagata tcacataacg tcatataacg tcatgtgaca
     3841 taattgcatt gtatccgctt tctttgtgtt tgtcaatagg aaaaatttat ttctctaaaa
     3901 aatataaata atctgcagtg aaacttgagt acatatacta atttcgaaaa atgcctatga
     3961 tttaaataat tatggtgctg ggatgaaggt ttataagttt gtcttgattt gtttagaaga
     4021 aatcgttttt gcacacagtt gaattaggaa actactggag tggaaaataa agtgatttga
     4081 cgggtagatg ggtgcactta aatttgaaaa tggcttaaaa tgctttattt tgaattgcag
     4141 aatttctttt agtacgcaat ttatggtctt aaaactgatt aaaaagtgat acattgattt
     4201 taatacaatt tatgatacaa aaaatgacct cctttcttaa ataaaagagg tcattttgtt
     4261 ttgtctcata atcgattgtt tttgatacag tagttatatt cagaaaaaat aaagactctt
     4321 ctgagtttat aatcctttgg attatatacg gatacagatg tagacataaa acaagctcaa
     4381 ttttcaaaaa tggcattact cacctttttg gtgaattatt tgtataaaaa aaatatagaa
     4441 aagacaccct gaaatccttt agaattaatt tggctaccaa ttcataggag gattcaagat
     4501 gtctcatact cagcttatca aagataccct aaatattcta gacctaaata tctatttcga
     4561 ggaaaattgt ttaactaaag aaaaatacaa agggcaaatt tgcttgattt acaaaggaac
     4621 tcttctgtac aagccagaag agtgttccca ttgtctttgt gtcgtcccct ctaggatcat
     4681 tcgttggggg acgacaaccg ttcggttgtt actgaatgat gtgtctgagt atcgcactta
     4741 tctggagctg aagaaacaac gatttaaatg taagtcttgc caaagaacat tcgtagcgga
     4801 tacctctgtt gctgaaaaac actgtttcat tagtcaaaaa gttcgttggt ctgtcattgc
     4861 tcgcttaaaa gagaatactt ccatgacgga aatcgctcgt cagaaaaata tttccacttc
     4921 ttcggtctat cgtgtcatga agcgattcta ccgcccattg aatcctttca aacagacttt
     4981 gccaaaggtc ttatgctttg atgaattcaa atcggttcga agtgttgcca gtgcaatgag
     5041 ttttatcatg atggacggac aaagccatgc attattggat attgtcgaaa atcgacgctt
     5101 gccttattta gaacgctatt tttctcggtt ttcattagcg actcgtgaag ccgttcaatt
     5161 gattgttatt gatatgtatg cgccttatgt ttcgttggtg aaaaagcttt tcccgaatgc
     5221 tcagttgatc atcgatcgtt tccacatcgt ccaacatatt ggcagaactt tcttgaatca
     5281 tcgagtgaaa gaaaccacgg tacgacttaa aggaaattcc cactctcaac gagggttagg
     5341 gaaaaaattg aagcgctatt ggaaactcct acaaaaagaa gaagcaaagt taaactatga
     5401 aaaacgggtt tggcgtgcca gttttaaaga ttatttgact gaaagtgaga ttgccgatcg
     5461 actgttagct gcttgtccca acttacgcca aggctatcag ttataccaag acattcttta
     5521 tgcggtaaag aaaagagatc agtcactatt tgaggattgt ttaactagag acattagcgg
     5581 tctgccagaa acctatacaa ccactttacg aacgtttaaa aagtttctgc cacagatcca
     5641 aaatgcgctt cactacagct attcaaacgg accattggaa tgctt
//
LOCUS       DAZKCH010000118         5569 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000118 DAZKCH010000000
VERSION     DAZKCH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.121"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..862
                     /locus_tag="ACG84X_002601"
     CDS             5..862
                     /locus_tag="ACG84X_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9128411.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            884..1393
                     /locus_tag="ACG84X_002602"
     CDS             884..1393
                     /locus_tag="ACG84X_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFP9128412.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            1430..1831
                     /locus_tag="ACG84X_002603"
     CDS             1430..1831
                     /locus_tag="ACG84X_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128413.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            1943..2296
                     /locus_tag="ACG84X_002604"
     CDS             1943..2296
                     /locus_tag="ACG84X_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128414.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            2330..2773
                     /locus_tag="ACG84X_002605"
     CDS             2330..2773
                     /locus_tag="ACG84X_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9128415.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            2790..3875
                     /gene="uxuA"
                     /locus_tag="ACG84X_002606"
     CDS             2790..3875
                     /gene="uxuA"
                     /locus_tag="ACG84X_002606"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFP9128416.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            3868..4581
                     /locus_tag="ACG84X_002607"
     CDS             3868..4581
                     /locus_tag="ACG84X_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9128417.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(4788..4937)
                     /locus_tag="ACG84X_002608"
     CDS             complement(4788..4937)
                     /locus_tag="ACG84X_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128418.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            5333..5533
                     /locus_tag="ACG84X_002609"
     CDS             5333..5533
                     /locus_tag="ACG84X_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9128419.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         1934 a          854 c         1210 g         1571 t
ORIGIN      
        1 ggaaatggct gaaataatgg ataatcaaac aggtgctcct gaagaaatca cgaaaaaaga
       61 tgtaacaaaa gcctatctga gatggcattt tgcaaacgaa attcctcact cttttgaacg
      121 ttacttggcg ccatcactac tatacggaat gatgccaatc ttgaaaaaac tttataaaga
      181 tgaagactct ttaaaagcag catataaacg gcagttactg ttcttcaaca ctcaattaag
      241 ctggggtggc ggtgtgatta ctggcctaat gtcttctatg gaacagcaaa gagcagaaga
      301 agagtatgaa gaaaaagaga tcttgatgca ggatgacttg atgtataaca cgaaagcggg
      361 attgatgggg gcactagcag gaatcggaga tgcaatcgat tcaggaaccg tccaatatat
      421 ttttatcgca atcgcggtac cttgggcaca acagggaagt cctttaggcg cactttttcc
      481 ttttatctgc tttgggttgt atcaggtttt actaggggta tttttcgcaa gacaagcttt
      541 cactatgggc cgtaatgcta caggcctaaa gcaaaacact ggtgttcaga cagcgattga
      601 aatgctatca gttttagggt tgtttatgat gggggtgctt gcgggaaact atgtaaaagt
      661 agaatcttca ttgaaatttg cgatatccgg acgtgagttt gttatccagg aaattcttga
      721 tcaaatcgtg ccagggatat tacctttagc tgtcgtaatg ggtgtgtact tgttctatac
      781 gaaaaaagga ttgaaagtca cacaagcatt attatggctg actggaatat taattgtgct
      841 agcaggaatc ggtattttat aaaaagaagg gaacgtgaat aagatgggtg tagtcaattt
      901 agcgcgtgtg gatgagcgtt tgatccatgg gcaagtaatg gtaacgttat ctcaaaaaag
      961 tggagtgaat tccatttttg ttgtagacga agttgtagca aaagataaat ttatgagaga
     1021 tctttacaaa aatgcaggaa gccgtacagg acaaaaaaca attgtcatta caccagagaa
     1081 agctaaattc tattgggatg aatatcaatt taaagaatac aattgtattt tgatcgcaaa
     1141 aacagtccaa acgatttacg acttagtaaa acacggaatc cccatggaag aattgaatat
     1201 tggagggatt gctcaaaaaa atcctgatac agatctttta gtgacgaaat ctgtttattt
     1261 aaataaatca gatgctgaaa aattgaaaga aatgaatgaa caatatggcg taaagaatat
     1321 ttattttcaa gccactccat ctgcacctaa aacaggatta aaagatgtat tgaacaagtt
     1381 tgatttgtca taaacaaatg cttagaaaaa agataaagag ggcgaaaaaa tgaagaagaa
     1441 cgagctgttt cgtgattggg aatttcgtta tcgctatatt taccgtaagc gccgtacaaa
     1501 aaagagtaaa cagcgttttc tttcagcatt agtatcagat atttacagta tgagaacaga
     1561 tgtgacagtc attgcttacg atacgctagc ctaccgatca aaaaatattt atgttggaga
     1621 tatcgaaaaa gcagagaaag ttatctgtac ttattacgat acacccgttc atgcattagg
     1681 aagttatttc atgtttgatt ggaaagacca aaggaaaaaa acaatctact ctatattatt
     1741 gtccttcatt ttgttgttca gtttaggttg gtggggaatg atgatatata acaaaaatcc
     1801 tcatcacgta ttcgatctgc tatccgtata aacaggtatc actgtactag catttgggag
     1861 ctactttttc ttattgggaa aagcagctcg cggatggcct agcagacaaa cttttattcg
     1921 aaatacttca tccatattaa cgatgctaga aatgatccgt acgattgatg atccgagtgt
     1981 agcgtatgcg tttgttgatg aaggctgtta tggagaaaag ggcttagaca gcgtgagatc
     2041 gggtatgaaa aaagaggcta ttctttttta tctagactct gttggggcag atacaccgct
     2101 acagttttcg ggaaattatt tttcaaataa agaacagtgg ctgaaacaag ttgataagtt
     2161 gaaagaaaaa aacgtcaatt atatttttag tgcaagaaaa aagcaagcgc agttcttcta
     2221 tttgaccaaa acagatttac gagggaaaac atttaattgg caaaatgcca atcagattat
     2281 tgctcttttt cgataagtaa aaagtgcaaa acaaggagtg agaagactaa tgttggaaat
     2341 catgatcgtt acacatggta agttgagcga aggactgaaa gatgcggcgg aagtaattgt
     2401 cgggacatcg agccatattg aaacaatgtg cttagagtct ggggaggaca tccaaacatt
     2461 cggagagaag gtcaaagaaa aattaactat gatcaacaca gcagaaccca tgctagtatt
     2521 tgttgatcta attagcgcaa gtccgtacaa tcaagcgctc ttggcagtca atgaactgac
     2581 tgaagaaaag aaagcagcca cttatgtcat agggggcgtg aatctgccaa tgttgttaga
     2641 agcaatcaat catcagatgc ttcacacacc gatagaagaa gcggtggaac aaattgtcaa
     2701 acaaggaaaa gataatttaa ctgtttggca tgcttcagcg gaagaaaaaa aattagatga
     2761 ggacgatttt tagaaggaag gctgaaaaga tgaagtgggg atttagatgg tatggtgaaa
     2821 aaggggattc gatcccatta aaatatgttc gccaaatacc gggaataaat gggataattg
     2881 gaactttgct gactaaaatg cctggagatg tttgggagat ttcagaaatt gaggagttga
     2941 aagcatctgt tgagagccaa ggactggaac tgcttggaat tgaaagtgta gcgatccacg
     3001 atgcaatcaa ggcagggaca gatgaacgag attactatat tgataactat atacgaacaa
     3061 tcaaaaactt gtctcgatgt ggggttcgat tgatttgtta tagcttcaaa ccaatttttg
     3121 gatgggcgaa aactgatttg tttaatgaaa acaacgatgg aagctattct cttttatacg
     3181 atcagaaaat cgtcgatcag atggagccag gagaaatgta tcaattgata cacagccagt
     3241 caaagggatt caaattgccg ggttgggaag aagaacggtt gaaaaaattc gctcagctgg
     3301 aaaaactgta tgaaggaatg accgaagaag aattatttga aaatctgact tattttttag
     3361 aaaaagtgat tccagtgtgc gaaaaagcag atgtaaaaat ggctatccat ccagatgatc
     3421 cgccatggga actttttggt tttcctagag tgacgaaaaa tcttggcgac ttgaagaaaa
     3481 ttctaaatgc agtagattct ccatataatg gactaacgct gtgcacagga tctttagggg
     3541 caaatccgga aaacgattta gttgaaatca tccatgaggt aggttcgcgc atccattttg
     3601 tccacttcag aaacgtggag tttttaggag aaagaaagtt caaagaaacg gcacatccct
     3661 ctacagaagg ctcccttgat atgtatcata ttatgaaagc gttggtgcaa gaagggttcg
     3721 acggtcctat acgccctgat catggtagaa ccgtgtgggg tgaagtggct atgcctggat
     3781 atggcctgta tgatcgtgca atgggactca cttacatgca aggtctatat gaggcgataa
     3841 gtaaggaaaa accactggga gagcattatg aataaaatca agctcttcat ctttgatatg
     3901 gatggccttt tattagaaac tggacgttta gcttatcgtg cttatgtaaa atcagcacaa
     3961 aagtatgatt atgaaatgcg taaggaagtc tattatttac taactggcca aacagaaatg
     4021 gcgataagag aacaaatggg cattttgtac ggagaagatg ttccatatat caaatggcga
     4081 gaagcaatca atcaatataa agaaaaaatc gtgaaagaag ataagagagt atatacgaaa
     4141 aaaggagcag aagaaatttt atcttttgca aaagaaagag gaatccatac aatcgtggct
     4201 tcgtctaata cacgggtaaa agtagaaatg tatttaaaaa tggaaaatct atatgccttg
     4261 tttgatcaaa tcatttcagg ggatgatgta aaaaaaggaa agccggaacc agagatcttt
     4321 ttgaaagctt gttcaaaaat gaatattcct ccaagtgaag cacttgtatt tgaagactcg
     4381 attgcaggga tcgaagcagc aaggcgagcg ggcattttgt cttttctcat caaagatcat
     4441 ttgatagggt tgcccgatca taatgggaag cataagttga aagtagatgt aagtttatat
     4501 gaatccaata aagcagacta tgaattttat gacctgcatc aagcaaaacg atttttagaa
     4561 agtaaagggt tgtatctcta ataaagagga ctattttcta gtcctcttta tttattgtcc
     4621 tgcacgactg agggaacaga tgaaaaagaa gtaatttttt attttgaagt atctacctta
     4681 tttgtagtga acaatttaga acaaacacaa aacgcatcta ctgttatcta ccagtagatg
     4741 cgtttaaaga gaagaacgag aatcgtccat atgagggttt ccactcctta tgcagatttt
     4801 tttaattctt gcactgcttg ttcgatcgta acacctgtcg ctacatgatt ggtattttct
     4861 ttgtcaaaaa cgacaaatag attcaaatct gtatccaagg ttactcgata ttgtatatct
     4921 ttgttataga atgtcatagc cattctcctt tctttaaata cttgctgaaa ggcaacgaac
     4981 gcgttgataa cgaaattcca tttataagta taccaccaat tgaaaggttt tcatagttaa
     5041 gaaattttaa agtcaaaagt tgcagataaa agcaaataaa caagaaaaca aaaagtgaat
     5101 caatcgcggt tattcaactt tttcttcgat tcgaagacaa tagaagacaa tgaattttat
     5161 atttcattgc attatccttg tgttattaga aaaagcatga tatattaaat gagtaatcta
     5221 ttttgaaacg taatttgagc gatatatcta catagataaa actccttttg cctatcaaat
     5281 atttattgca acgaaaaaac gtacattgat acgtatcagg aggaatttat ttatgaataa
     5341 cggtacagta aaatggttca acgcagacaa aggttttggc tttatcactg gtgaagatgg
     5401 aaatgatgta tttgcacatt tttcagctat ccaaggtgac ggcttcaaaa ctttagaaga
     5461 aggccaagca gtgtcttacg atgttgaaga tggtcaacgt ggccctcaag caacaaacat
     5521 tgttaaagct taataaaaat tgacttttaa ccgtcttttc gaaagaaaa
//
LOCUS       DAZKCH010000119         5481 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000119 DAZKCH010000000
VERSION     DAZKCH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.122"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(43..409)
                     /gene="ssrA"
                     /locus_tag="ACG84X_002610"
     tmRNA           complement(43..409)
                     /gene="ssrA"
                     /locus_tag="ACG84X_002610"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(580..1353)
                     /locus_tag="ACG84X_002611"
     CDS             complement(580..1353)
                     /locus_tag="ACG84X_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9128420.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1497..1847
                     /locus_tag="ACG84X_002612"
     CDS             1497..1847
                     /locus_tag="ACG84X_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFP9128421.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1828..2544
                     /locus_tag="ACG84X_002613"
     CDS             1828..2544
                     /locus_tag="ACG84X_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFP9128422.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2544..3992
                     /locus_tag="ACG84X_002614"
     CDS             2544..3992
                     /locus_tag="ACG84X_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9128423.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4062..4571)
                     /locus_tag="ACG84X_002615"
     CDS             complement(4062..4571)
                     /locus_tag="ACG84X_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128424.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4561..5286)
                     /locus_tag="ACG84X_002616"
     CDS             complement(4561..5286)
                     /locus_tag="ACG84X_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128425.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1864 a          955 c         1095 g         1567 t
ORIGIN      
        1 aaataaggat ttaagcatct agcgaaatct gctgaaatct cacaatggag acggcgggag
       61 tcgaacccgc gtccaaacac atcgccactt aaaaatctac gttcatagtc aactcattta
      121 aggattcact ttacagcttg ccgagtgaca ggcattctgt atcgctagtc tgatgttctc
      181 tttttcaact tacagacgga aagttgaaac gtatcccact aaagttagga cccttactcg
      241 agcacatggg cgatgccgag aggatctacg ctaactgttt ttaggcagct aaagcgtaag
      301 agttgttttc gtttttagca gttatattta actgtaacgt ttttacgtag acgtaaccta
      361 cgaaacgcaa ttcaagctcg actgtgcctg tcgaatccgt aacgtccccg ttagctaaca
      421 agggttacgt gtatttttca tacaaaatta gtatagcata tattgggata aattcaataa
      481 aaaagcgaat catatcccat tatttatata ataactgccc ctttcttaag aaaaaataag
      541 cgattttctt aagaaaagag gtagcttcaa aaaaagatct taaatcagat caaaatactt
      601 caatgcgtgg acaattccgc cttctgtatt tttctttgtg ataaaggtag aaagttcttt
      661 taatccgtca taggcgttgc ccatagcgat tttgttgtcg caagcttcca acaaggcaaa
      721 atcattcgga ccatcgccaa atccaaaagt aggaactttt tccagctgaa gttctttttg
      781 cagacgtttg acacctgccc cttttgagat tcctttcttc actgtatcga tcgagtaagg
      841 accattccga taaaaagtta gctcaggaaa atgttcgtga tagtattcgt cacctgattg
      901 agataagatc agcaacatat ttactgtgtt ttctttaaag cctaaaggat caatttccgg
      961 aacatctgaa tgaatgaagt cgtaagcatt gatcattgtt tggctatgac cggtacacca
     1021 gattttctga tcgttatagt aagaaagttc atgaccgttc aactgtacat gatcatacat
     1081 tttttgacat tcttctgaag aaaatgtttg agaatagatt tcttcgccgt ctactcgaat
     1141 gaaagaacca ttcatggtga ccgcagaagt aatgcccgca tcttccatga tagagtggat
     1201 ttctgcttct gtacgtcctg tagcgatgac ggggagaaca ttgttttctt ttaatgcgtt
     1261 catagctttt gccacttcgg gtgtgatttt tgatttcgca tctagtaatg ttccatcaag
     1321 atcaaagaaa gtgattgcac gataatttga cacaaataaa actccttttt tattggaata
     1381 agtttatctt aacaaagaat gaacaaaaga caaacctttc gtgaagaatt cctgaacata
     1441 ttggttcagt caacaattta gagtatacta taagaagaga atttaggagg gaaagaatga
     1501 tttttttcag tattggtatc ttattcttaa taattggcag tctttttcgg attctgccct
     1561 caaaaggaaa tctgcctttt tatgggtatc attcgcctct tgccgcaaaa acagacgctc
     1621 attggcggct ggctcaaaag acaagcggaa actggttttt tcttatgggc ttactgatgg
     1681 cattgatcgg ctattattta aagacatctg ggcatacgaa ttattttctg attgaaatgc
     1741 ttctgctagt atttccaatt atgcctattt ttattatgac agaaaagaaa ttacagaaat
     1801 atgacctgga aactggaggg aacgataatg aatattttaa tgattgaaga taatcaatct
     1861 gtttctgaaa tgatgcagat gtttttctta aatgaaggtt gggaagcaac tttcaagtat
     1921 gatggaaaag aagggctcga tgccttttta gaaaacccac aacattggga tatgattaca
     1981 ctagacctga atttgcccac actggacggt atgctagtag gaagagagat ccgcaaagtt
     2041 tcaagtactg tgccgattat catgctgaca gctagagatt ctgaaagcga tcaggtgatc
     2101 ggcttagaga tgggggcaga tgattatgtc acaaaacctt tcagtcctct gacgcttatt
     2161 gctcgaatga aagctttgca tcgccgtagt gagttggcag aagcaagaga agaagcagta
     2221 gtttcagatg atcattttga tatcgagact agtcatttca agatgaatac gaaaacacga
     2281 gaagcgtatc tggacaaccg gccaattgaa ggactgacgc ctaaagagtt cgatctattg
     2341 tttactttag caaaaaaacc acgtcaagta ttctctcggg agcagttgct tgaattagtc
     2401 tgggattatc agtactttgg tgatgaacgg acagtggacg cccatatcaa gaaattacga
     2461 caaaaaatcg aaaaggtcgg accacaagtc atccaaactg tttggggagt cggctacaaa
     2521 ttcgatgatt ctggtgttgc ctaatgcgtt atttgtatca gcaactctta gctttctgcg
     2581 gaatggtcgc gttgatctta ttgatcgttg gagtttcttt tacacaactg acaaaacaaa
     2641 cgattgaaga aaacaattac cagcaactgt ttggatatgc tgaatcagtt gaaaagacaa
     2701 cgcaaaccta tgccgatacg ctcccgcagt ttagtcaaga tcaggcgttt caaaatgcat
     2761 tgctgctgac agagcaagta ctgacagaac aaaatgtgaa ctttatattt atcgataaaa
     2821 acgaacgtgt catttatccg actaatacag ctttactgaa ttttacctta acagctgatc
     2881 aatggaaaaa tctgaggaat ggacgtcaag aaaaattcac atcgaataaa aatattttag
     2941 gacaagcaca ggcgacctct tacgcacttg tgccatttaa tttgaatcat gaattctatg
     3001 gagcacttgt agttagtcaa cctgcgcgaa atatcgataa cagcgttcgt ccaattacac
     3061 tgaacctgtt caaaggattt attttttcca gtatcgttgc agttattgcc agctatgctt
     3121 ttgcagcatt ccaagttaag cgtatcaatc ggttaaggaa tgcgacgaaa gaagtgacga
     3181 atggtaattt tgatgtacag ctccccgtac atgacaaaga tgaatttgat gagttagcag
     3241 atgatttcaa taaaatgacg aattcattga aagaatctca agcagaaatt gaagaacaag
     3301 aaaatcgtcg aagacaattt atggcagatg cttctcacga gatgagaaca cctcttacga
     3361 caatcaacgg acttctggaa gggttagaat acaatgcaat ccctgaaaat cagcgagaaa
     3421 acgcgattaa attgatgaaa aatgaaacag agcgtctgat ccgtttggtg aatgaaaact
     3481 tggattatga aaaaatccgt acgaatcaaa tcagtatggt cattaaaaaa ttcaatggaa
     3541 cagaaacatt gaaaaatatt gttgcacagt tagaagctaa agcagaagca gcaggagata
     3601 cattgacatt gaaagccgtt gatgatattg atgtttacgc tgattatgac cgatttgtcc
     3661 aaatcatggt caatattatt caaaacgcga tacagtttac tgaaaacggc caaatcacga
     3721 ttactttaga aaaaggctat cttgaaacga tcatcacgat tgaagatacg ggaattggaa
     3781 tgtctgaaca acaaatgaaa agtatctggg atcgttatta taaagtagat ccttcaagaa
     3841 aaaatacaaa atatggtgaa tcaggattag gtttaccaat cgtgcagcaa cttgtacgct
     3901 tgcataaagg aaaattagaa gtagaaagcg aactaggaaa aggaacaaaa ttcgctgttc
     3961 gtttgcctga cgtagaaatc aaaaaagagt aaaaaacaag cggtataaaa gatcatgaat
     4021 cgatcttcta taccgcttgt ttttactata aaatgattga tttagcccgc gggctctaaa
     4081 cgatcaatat aaggactttg agcaatagta gcatcatgag taaagagtaa gataccttga
     4141 ttttcttcat gagctaaata agaaagcaag tggagtagct cttggatctc caatacacta
     4201 agttcatcaa atgtatcttc aataacaata ttgtttcgct tggaaagcaa ggcatgaagt
     4261 aattgcagct ttactttttc aaaagacgtc aactcagctg ccgcacaatt aagcaaggaa
     4321 ggagagatat caagtttttc ttgataggcc aaacgatctt gtttgatttc tttttccggt
     4381 acatccaaca ggacatggtc tttaagattc agataaggaa acatcggcca atttttttgg
     4441 atgatcgcaa aattatccag ttttgcaaca agaacctctt ttttcaagtg ctccaatatt
     4501 ttatgctgtt tttcgagagg acacaaaata acggtcaagt gttcagcatg aatcaaatat
     4561 tcaggtttca ttacgtccag gcctcctact ttgcaaatga tggataaaaa aagtgaaagg
     4621 gaatagacta agaatgagac agcatccact gagcccaata agagtttggg caaatccctt
     4681 aagtatatct gtgaaaaaaa gatcattttg gaaatcgatg gtaaaaaaag tctgttgatc
     4741 catcggaatt gtaagtccgc ttaccgaagt caagatatca cggatatctg gcagttcagt
     4801 agtctttaag acaagaaaat tgatcctttg aagaagcgct tcataaactg actggaagct
     4861 tacgatccac aataaaacca agatacaaca aagaaagaga ggaaagaaca gctgccagaa
     4921 aataaaaagg aataatttgg ttttagaaag accagtcagg tgccaattga tcaattcctg
     4981 cttgttttgc ctgactgaat agtaaaagaa aaagataaaa aggaaggcaa atagaaaaaa
     5041 taaactgaat atgcctttta tataaaatcg gctagctaat tctaaagccg gaagaagctc
     5101 tgtagatgca gaagcgccaa taaatgaaag ccgatcttgg acttgattgg ctaaagccga
     5161 ttgcaaatgg taaagagtca ggcatgctat caataaaaaa gcagaaaagc ttgaaaataa
     5221 acaatagagt attgtctgct ttttgtaata aattaatcga gcagtagcat agcggattat
     5281 tttcatactt ttcacctcta taaaaagtat agaaaatgaa tatgaataaa gtatgaaatt
     5341 cctttagtga aatcacgaat taaaaccaga aaatattttg taaaaagcaa gaggttgtga
     5401 agaagctgcc ctattctatt accgtagatg caagcttttg aacactgttt attcgaaaag
     5461 aggagcagcg acaataattt t
//
LOCUS       DAZKCH010000120         5288 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000120 DAZKCH010000000
VERSION     DAZKCH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.123"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..234)
                     /locus_tag="ACG84X_002617"
     CDS             complement(<1..234)
                     /locus_tag="ACG84X_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128426.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSS"
     gene            complement(532..1506)
                     /gene="sgrA"
                     /locus_tag="ACG84X_002618"
     CDS             complement(532..1506)
                     /gene="sgrA"
                     /locus_tag="ACG84X_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFP9128427.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(1702..2541)
                     /locus_tag="ACG84X_002619"
     CDS             complement(1702..2541)
                     /locus_tag="ACG84X_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFP9128428.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            2726..3613
                     /locus_tag="ACG84X_002620"
     CDS             2726..3613
                     /locus_tag="ACG84X_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFP9128429.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(4207..4902)
                     /locus_tag="ACG84X_002621"
     CDS             complement(4207..4902)
                     /locus_tag="ACG84X_002621"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFP9128430.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(4886..5284)
                     /locus_tag="ACG84X_002622"
     CDS             complement(4886..5284)
                     /locus_tag="ACG84X_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFP9128431.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         1681 a         1068 c          777 g         1762 t
ORIGIN      
        1 agaagaaaac tcgactttta tcatcttgtt ttctgaaaga aaagataatt tatattctgg
       61 atacctttcg caaaacgatt ctgcttgttg aatcaccgaa ttcatcttag ccagggtgta
      121 gtttagatct aaagcgatat ccttcaccac atataatttc tcgtctcttt cataacaata
      181 gttcaaaaat tgatatactt gcctttcatt gatatcaata aattcttcaa acaaagtaca
      241 tactcctttt tatctattat ttagacttat tccgacagct acatgaataa cgtacaaata
      301 gattcgttac tgatttttca gagatactac catgcgcagt gtgcattgtc aattattctt
      361 gctcttattt tccatttgtg ttcctgttat ttcctgtttc tcaaatatgt tagtaaacaa
      421 aaatagatct ggcaaagcta caacttcgcc aggcaataca gcactctcga atgaaatatt
      481 cactcaaaaa tctatcgttt tattcaattt tagatctgtt gcttttattc tttatttcac
      541 tcgatggaag agagaacgaa aatagcttgc tcctacaatc aaaatgagta acacacccat
      601 ccatgtaatt agcttgttca aggttctact accagtttct ggtaaatcgc tttttctatt
      661 atctgtttct ttcgcttttt cttgatgatc aattccacga gaaacaaaat caggctgttt
      721 tagcacactt tttaggttgc tccctgcatt tctcttttgt tccttagttg gtatgatagg
      781 taccaaatca agttcattat ttacttttcc tgtgctgctt tcgctgctcg tgcttcctgt
      841 gctactctca ctactcatgc ttcctgtgct actttcacta ctcgtactct ccgtactgct
      901 ttcgctgctc gtgcttcctg tgctactttc actactcgta ctctccgtac tgctttcgct
      961 gctcgtgttt tctgtgctac tttcactgct cgtactctct gtactgcttt caccgctcgt
     1021 gttttctgta ctgctttcac tacttgtgct atccgtactg cttggcggtc caacaactgt
     1081 ccaactgctt ggtttcaaat tctccgtgat cgtcatctgt ccatcataaa aaacaatcaa
     1141 atcaacttta tctttactct tgatctcatc aatcgatagt tctgcagaaa tcattattgt
     1201 atactcaata ccagcggtcc attgtacgtc ttttaaataa acttccccaa taactttttc
     1261 tgaacttcca ttaccatccc aaccatatgt tagaacagca tgtacatcac tagcattcac
     1321 gcttttgttt ggtttgactg gaatagtaat gacttgttgt gtcatgtcat aaacaatccg
     1381 atcagttttc acagtaaatg aaagattctc atttgcccgt tcatttgcag aagtactgat
     1441 tccaatcatt gctgcaatta tactcagccc aagaataaca aataatacgg tcgctgtttt
     1501 cttcatttct atcactctcc atataattac cttctatttg ataaaggaat tatataaaat
     1561 gaaaatgatg agaacacgac agtcagttgt gaaaatctaa caaaagatgt cgtgtattcg
     1621 cttgaatttg tttacttttt cgtttaatca atgacagact taaaaaagca agaccgatat
     1681 cagccttgct ttcttcatct tttattgata aacagcagtg tatttcttca tccgctttgt
     1741 tttatatgca tagagtaaca aaccaacaat caagactaac aagaataatg tagttgatat
     1801 agatgcttca gccccaaagt ttcccccagt aattattgta ttttgcgatt ggatcagagt
     1861 ggagaaaaaa ccttgttctt gcgttccgct gactggtata cccaaaatag ctccttgtgt
     1921 ccaattccaa gtaatatgag caccaatagc cgtaaataaa cttcctgtac tgtagataag
     1981 tgcgctgaaa aagcaacctg ctaaaaagat attgaaaact gccagaaatg tcatgttagg
     2041 attcaatccg tgcaaaagag caaataatgc agcagatcca atcattgcta ttaacggacc
     2101 aaatctaagc atctgatgct gaaaaaagcc acggaataaa agctcttctg atgcccccac
     2161 tgcaataaat aaaataaaac tcgttatcag cggcacaatg tttgcgtttc ctgaatctaa
     2221 ccgatacgcc cccgtcaaat ataatggact agtaataagc agaaacactc caattccaac
     2281 aacgagacct cccgctaaat acccccagtc ttttcctcga acagaaacac cataatcttc
     2341 tattcttttt ccttcgacct tactagcaag aaataaagct agtaaaaaaa cagctaaatg
     2401 tccgaccgta ccggcaattg ctccaatcca ttcactattt ccaataaaca tatccgcaag
     2461 tgcattattg acaagaattc ctaaaacaaa accaactaag actattaaaa cagatccaat
     2521 caaccgaata atcctgatca tctttcatcc ctcctttata ttaagtttaa caaccctttt
     2581 ctttcttgtc tcgtgaaaac tatgtaaatg ttctccatca tagagagaat agatttttac
     2641 gaactaagaa tatctacagc aaccttacga aaatgaaaga ctgtctccct aattcttctg
     2701 ttagactgtt tttaataagg aaaggatggg aaattttttg aaaaaacaac tactaattat
     2761 gtgcctttca gcatgtgcaa ttttactatt ctcaggttgt agcaagtcca atgaaacgat
     2821 tgcaacgttt aaaggtggaa cacttacagt tcaggatttt tatgataacc caaaagttaa
     2881 atcaaataat caaacactat taaaaaaaat gattgtcttc aaagcatttg atgatgtata
     2941 cggaaaagag atttcttcaa aggaagtaac aaaagaatat aatgaacaaa tcaaaaaact
     3001 cggtccaaac tacaaggaac aattaaaagc agttggccaa acagaagaga catataagaa
     3061 actctttaaa cagatgctgg ctttccaata cggtttgaaa gccaatgtaa aattaacaga
     3121 taaagatcta gacactgctt ggaaagaatt ctatccagaa gttagtacac agatcattct
     3181 attttcgact aaagaagaag cagataaagc aaaaaaagaa gcaaatgaag gagaaaattt
     3241 ctccaagctt gttcaagctt atggaaaaaa taaaacatta aaggaaactg atggaaaaat
     3301 gaattttgat tcaaccaatc cagagattcc tactgaagta aaaaaagcag catttaaact
     3361 aaaaaacggg gaagtttctg atatcattcc tgtaacagat ccaacgactt atcagcaaag
     3421 ctattatcta gtaaaaatgg taaaaaaaca ggataaaggt tctaataaag acaaatacaa
     3481 atctgagcta gaaaaaattg ctaccgaagc aaaaactctt gatacggaat tcatggataa
     3541 aacaatccgt aaagtgatga aaaaagacaa tgtaactatt aaagatcctt atgtaaaaaa
     3601 tatattcaaa taaacaaatt tgacccaatt ggggatgtgg caaaatttga gaagtgattt
     3661 ttggaaattc cttcttattt ttgaggcaaa ccacttttgc cacaacttca tcggggcctt
     3721 tttttatttg taccaaaaca aatcactgga tttgttacaa tcatgaggat ataatttaaa
     3781 aaagtttttt atttctatca catgaatcaa tgcgccatta agtagattct ttcatgcttc
     3841 cctatttttt cacttgccgt atcgcttcaa aaacaactat cataaactca aactcgactg
     3901 aaaagttatt ttaaaaaaga ctaaaaatat cccttctgga cttgttcttc ttattctgtt
     3961 atactagaga aacacgaaag atatttttat gcgacacttt tcatttgttt ttatgaaatt
     4021 tattcaaaac tggcgtaact tcagagttac aaggatgtat tagaggttag ggaatacatc
     4081 gtttaaatga gaaataagta atagttagta atagtcaccc aaactttaaa ttaatgaata
     4141 ttgaatcgtc agatagcctc ctcgagtttt cgagaaggct atcgtttatt ttatggagaa
     4201 attgattcag aagtaatcag cgaccttttt tagttcacca atcgtttctg cttggaaagt
     4261 ttgcacccaa tcttcttgga agcccctcac tgctttatca atcgagggca tctctaatac
     4321 ttgatctagt agctctttac ctaacgttat cgcatgagct ccagatcgaa tggctgtagt
     4381 gacttgttca caatttttga aactagctgc taatattttt gttggtcttt gcgtacgttc
     4441 gatctcagtc cgcaacgaat caatcacttt catagcatca atgccttgat tttgcatcct
     4501 gttataataa ggtgcaatat aatctgctcc attattaata gctaaatacc cttgtaattc
     4561 tgtgtaaata gctgtaccgg taatcaaata accttctttt ttcaactttt tgatcgcttg
     4621 aaggcctgct tgattcaccg gcaccttgat aaacgtatct tttcccagtt cttctatgat
     4681 aactcgagca tcctctatca tttcttcttc cgttcttcct attgtctgaa tatggatagg
     4741 aatctgtccg attatttttt tgatttcttt catatgcgag aagaagtttg acgctccttc
     4801 ttttttcaga attgtaggat ttgttgttac gcctgttaaa ttcaaaaact gttgacaaga
     4861 ataaatactt tttgtatttg ctgtatcaag catgatttcc atatagcttt cccccattct
     4921 gatcctcttg atcgatttta atgattgtcc cctttcttaa atgcggcatt tccttatctt
     4981 ctacatacat tgttcctgga agttccggct catgagatcc atcaaatttt atcgtgatat
     5041 gtcctaattc attcaaatta gtttggacaa catctcctac tgctgtgatt acatacattt
     5101 gtttatcaaa acagagcttc atatcacaag ttatttcttt tcttacctga ttcaattcaa
     5161 tcttataaca ataatctgtt aatgtttccg gtgcttcatc tccaaataaa atcattattt
     5221 tttctttcct gaatacttct gcttctatac caacatctgt tacaaccgtt tcaaagatcg
     5281 tcatctct
//
LOCUS       DAZKCH010000121         5266 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000121 DAZKCH010000000
VERSION     DAZKCH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.125"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..251)
                     /locus_tag="ACG84X_002623"
     CDS             complement(<1..251)
                     /locus_tag="ACG84X_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128432.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDR"
     gene            complement(211..1965)
                     /locus_tag="ACG84X_002624"
     CDS             complement(211..1965)
                     /locus_tag="ACG84X_002624"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128433.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(2075..2644)
                     /locus_tag="ACG84X_002625"
     CDS             complement(2075..2644)
                     /locus_tag="ACG84X_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFP9128434.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(2662..4077)
                     /locus_tag="ACG84X_002626"
     CDS             complement(2662..4077)
                     /locus_tag="ACG84X_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128435.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(4088..4756)
                     /locus_tag="ACG84X_002627"
     CDS             complement(4088..4756)
                     /locus_tag="ACG84X_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFP9128436.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(4886..>5266)
                     /locus_tag="ACG84X_002628"
     CDS             complement(4886..>5266)
                     /locus_tag="ACG84X_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9128437.1"
                     /translation="LENIDIEKSWRENFNELDPFINYIFENKRIFDLILFQSAGTKYQ
                     DIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYATFYDILKHSYS
                     KEKTMLLTRRLYQFSVPGWIELLS"
BASE COUNT         1825 a          948 c          684 g         1809 t
ORIGIN      
        1 tccctatcta acaaccaata catgaaaagc aaagtaacaa acgatacggc aaaataaagc
       61 caacggggct ttgtattttc taaaactaat tcgtctatca gcatcattat aatgaatgct
      121 ggtaccatat taatgcagta tacaaaaaaa ctagaaatag aagctttagt taaagcttct
      181 gcgccctgat cacttaaagc aaatttgttt ttataaaaac ttttcattgt caagcctcca
      241 atcatttgca ttctcataat tagtgaccaa ttgtttatac acttgatgtt tagccattaa
      301 ttcattatga tttccacgtt ctactatttt cccttctgac aagacaagaa tttcatctac
      361 agatttaatg ctggataatc gatgagctat cataataact gttttttctt tcatcagatg
      421 ttgaaaagcc ttttgtagtt catactcatt atctggatca atagatgcac tggcttcatc
      481 cataataaca atctttgcat cttttaaaat tgctctggca atagctatac gttgtttttc
      541 tcctcctgac agataaactc ctttactacc aattaaggta tgctctcttt cgggaaattt
      601 ttctaaaatc gattcgcaac cggctaatct tagcgcgtca aatactttac ttgctggcgc
      661 ttgaggattt gctatagaaa cgttatcgta aatactctga ttgaatagtt tcgtatcttg
      721 aaagacaaaa gcaattgtgt taataattgt gtcttttgaa tagtgattta aaggcttacc
      781 accaatttta atctgtccct tatccacatt gtagaaacct gaaattagtt tagctatcgt
      841 actctttccg cttcctgatt ttcctactaa tgcataaatt cttttttgtt ctaaaactaa
      901 gttgaaattt tctaaaacac actcttcttt gtatgaaaag ctgacatttt caaatgcaat
      961 gtcacaattt ttaatctgtg tctcgttccc atattttagt tggtcttgct tcatttctaa
     1021 ataaagggag tctagtgttt cgactgcata tcttgcttca aacaagtgca tacttacata
     1081 cattattctc atgaaagaaa caaaaataat tccacttaaa aaaaacaaca tcaacaagtc
     1141 aacagctaat atcttgggag tggtaagaga agttataaaa aaggttatag gaactatcaa
     1201 aatgcaaact atgccaaaaa atagccattg aaaaagaaca aaaggtgttt tcccactcaa
     1261 agaatactta tatgcaaact tagcataatc gttaattgct ttattcaagg ctttaaatga
     1321 tgttacttta gcaccaaata tctttataac ttgaattccg cggatatatt ctaccgtttc
     1381 agagcttaac acatctaacg attcttgata tttttgaata aaatttgtat tctctgtcat
     1441 tttctttaac aagaatacac caattactaa catggcgatt agaaccaatc caattttaaa
     1501 gttaatgaaa aagcctaagg caactgataa aacaggtgtt actatggctt gagcactatc
     1561 tggaatcaag tgagcaattg ccatatgtgt tttagccgcg ttgtcatcaa ttgtctttcg
     1621 aatatatccc gaagaattta aatcaaaaaa acgaaaactt gcttctgtta aaccgctaat
     1681 tccctttttt ctcaaattag tctctaagcg aaacccaagg atatgagaaa ataagccaga
     1741 aaaaatataa aataaagctc ctaaagttaa ccaagcaaca gtttgaaccg cataactctt
     1801 agctaaatat tcatctccta caataattag agactgaaga aatttgtaaa tactgtaata
     1861 tccatagact gttaatacga cagaaaaatc agaaaataaa gtggctaacc atccgtagta
     1921 tttcatttta gggacataac taaataattt tttgtatact ttcatttttt cctcccccgc
     1981 attcaatttc ttctcttatt cgtttacaac tgttaatgct ttccgtaata gcgtaaatta
     2041 gagatgtaca aacagataaa aggtaaacta cgttctattt tttgtatttt tttaagactt
     2101 ttcttccaat caatacacca atcatagata aacttgctac aactaacact gaaatgattc
     2161 cccatatacc taccgcatag tggatcattg catccattgt tgcagcagat tgtcctttat
     2221 ctatccaatc ttgacgaaaa cgatctgtaa agaaccatat aggaatccac tgtccggcag
     2281 cactgcctaa ttgcattaga gcccaagacg caacttgagg aattgctcga tcatatccaa
     2341 atacagatag aataatatca gctaagatcg ccatactaat cgaactgata aaccaaggta
     2401 agtacgcccc gcccattaac gtaaaaaata acaataaaac aattgtgtaa atagtaaaaa
     2461 ttccttttct agggtagtta tagctaatat aaacaaatat gattccagat aataatccaa
     2521 aaatcccggg ggatatgctg tgaccaaacg ccccaccaat actactaacc attattgaaa
     2581 aaaagtaaat tactagggaa ataactgtag ctaaaccaat aaaaatataa tcttttgttt
     2641 tcatatatat tctcctcaat tctatttcgt tatgtcatta aaaatctgtt ctatcaaagt
     2701 tgaatcttct actctaagtt ttatatcttt ttttattcca ccatttttta aataaataat
     2761 tctattgcat gttttataaa gaaattccgg atcatgagta gctataacta ctgcaccctt
     2821 ttcttttaag tctttaataa ggtcagcaat cctttccata ttaatataat ccaacccact
     2881 tgtaggttca tcaaatagaa ataaattagt ttttgacaat gaagctatag aaaccaataa
     2941 tctttgtttt tctccaccgg ataaatcaaa cggtaattga tctttcattt tataaagttc
     3001 catttttttt aaaatttttt cttgctgatc tttactaact atttcattcc ccagggctaa
     3061 ctcgctcctc actgattctg tgaaaaattg gtaatccatt tcttgcatta ctaaaaacgg
     3121 cgatgacaaa ttttttttat tttcgattat ctttcctttg gtagggcgaa taatcttcat
     3181 gagtattctt agtaaggttg ttttccccac accgtttttc cctaccaaac caataacatc
     3241 tccaactttg acatcaaaat ttatgtcttt tagaatattt tcataagtaa tttcttcaac
     3301 ttttaataca tctgcactta ccttttcgat atagggaact tcaatcgaac tattaaaaat
     3361 gtcaaatttc cttaatgcgt tattgttttc agtttttaac aactgaatag ttgtagtttt
     3421 tacagttcta tttttaacaa atagaacttg atcaattaat tctttcaaat agtaaaaacg
     3481 atgttcagct ataacaatag taaatccttt attttttaaa tcacaaagta agtcagcaag
     3541 tttcttagtc gctttgaagt ccaaatttga agacggttca tccaatataa ttaatttaga
     3601 gtttagcgat aaactacatc caatagaaat tttctgccgt tcaccacttg atagcgaaaa
     3661 aatgttttta tctaatatat ttgaaagatc taataattca gctaattcat tgattctttt
     3721 atccatatgc tcttttgtaa atccaaagtt ttccatcgaa aatactaact cactcgttgt
     3781 atttgttgta aagaattgtc ctctaggatc ttgacttacg tagccaatat tttttgatat
     3841 actttcttgt gttaaggatt gtagcgagtt attttcaaat aaaatttccc caaccaattt
     3901 tccgtcataa agtcttggaa taagtccatt cattaacttt aatagtgtgg atttcccact
     3961 cccagaagaa ccagtaatca atgtaagact gccttttttt attgaaaaat taaggtcaac
     4021 aagcgcttgt tccttaacat ccttatatga aaaagaaaca ttgttaaatt caaacaattc
     4081 tttcacctca aatcaaaata cttaagaaaa aaatagtaac ggaaaacagg atgatatagt
     4141 ctaataagct catgtttgtt ttatagtaag aacttctttt cacaggagat tctatcccct
     4201 ttgttattgc attagcggtc atttcttcag caatcatagt tgcacgtata agaacgggaa
     4261 ctaacagaaa ttccaaatat tgcagaggct gaaaaaaaga caagcgaatg tttctcattt
     4321 ttaaagattc tttaatcatt cttatttcag aacgataagt cggaaagaat ctgatcacta
     4381 ctgtaatact taacattatt tttttcggta aatgtatttt ttctaaagag gataataatt
     4441 cattgctagt atagacacta accaacaacc atgagatcat tacgaccggc aacattcgaa
     4501 atacaatata taaggatgtc gcaaaaaata tagtaaaaaa ctctatcttg atagcatcaa
     4561 taattttcat tactaaaaac agaactgaat aaatcaagat gaaataaata catgtcttta
     4621 ttttacgaaa catcaatact aaaactgtag caataatgaa acaccccact tgaaatatat
     4681 ttccctttcc taaaaaaata atgaccggaa aaaaaatatt taaagtaatc aaggttaacg
     4741 gattgatttt tgacactctt tcacctccaa aaaataagat cgcactgtta tcttaagctg
     4801 ataaaaatgc accgttattc agataacagt gcgatcttat caaaaagcat aactgagaac
     4861 aattctcaat gcaagctttt tttaattaac tcagtaattc aatccaccca ggaacagaaa
     4921 attgatacaa tcttctggtt aatagcatag tcttttcttt tgaatagcta tgcttcaata
     4981 tatcatagaa tgtagcgtag aatgagtaaa tgtagaagtg gatttcttct tcattaaaga
     5041 ctaaattttg attgatcatt ccgatagtct ttaacttatc tagacaacag actgtctttt
     5101 tcgtcacaaa tgatgtaatt ttttcaacaa tatcttgata tttggttcca gctgattgga
     5161 ataaaatcaa atcgaatata cgtttattct caaaaatata attaataaat ggatctaatt
     5221 cattgaagtt ctctctccaa cttttctcta tatctatatt ttctaa
//
LOCUS       DAZKCH010000122         5261 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000122 DAZKCH010000000
VERSION     DAZKCH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.126"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            296..892
                     /locus_tag="ACG84X_002629"
     CDS             296..892
                     /locus_tag="ACG84X_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFP9128438.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(950..1432)
                     /locus_tag="ACG84X_002630"
     CDS             complement(950..1432)
                     /locus_tag="ACG84X_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128439.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1538..1735)
                     /locus_tag="ACG84X_002631"
     CDS             complement(1538..1735)
                     /locus_tag="ACG84X_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128440.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            2030..2788
                     /locus_tag="ACG84X_002632"
     CDS             2030..2788
                     /locus_tag="ACG84X_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFP9128441.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            2848..3276
                     /locus_tag="ACG84X_002633"
     CDS             2848..3276
                     /locus_tag="ACG84X_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128442.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            3322..3394
                     /locus_tag="ACG84X_002634"
     tRNA            3322..3394
                     /locus_tag="ACG84X_002634"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3355..3357,aa:Gln,seq:ctg)
     gene            complement(3544..3915)
                     /locus_tag="ACG84X_002635"
     CDS             complement(3544..3915)
                     /locus_tag="ACG84X_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFP9128443.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            4130..4315
                     /locus_tag="ACG84X_002636"
     CDS             4130..4315
                     /locus_tag="ACG84X_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128444.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(4398..4586)
                     /locus_tag="ACG84X_002637"
     CDS             complement(4398..4586)
                     /locus_tag="ACG84X_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128445.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(4610..4873)
                     /locus_tag="ACG84X_002638"
     CDS             complement(4610..4873)
                     /locus_tag="ACG84X_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128446.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            5031..>5261
                     /locus_tag="ACG84X_002639"
     CDS             5031..>5261
                     /locus_tag="ACG84X_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFP9128447.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWI"
BASE COUNT         1737 a          999 c          811 g         1714 t
ORIGIN      
        1 aattttctat aaaagcaagt aatttttaat ggcaatatca taaaaaaaag aagatagaga
       61 tttaataatt atatatcagc tgtttttttc aaataagcaa aaattcctaa aacacaacaa
      121 tgaaagcgat aactaagaaa atccttacat aacgattttt cttattaaaa ttgttttttg
      181 aacttcgctt attttttgtg agcatatctg tttacttact ttttgtaagg tgctatactt
      241 catttcgtaa tcaattaaaa aaatgcaaaa cgcaaatcaa aggagaaatt ttattatgac
      301 aacttttact gacactttga aaaaccgccg ttcaatctat catctaggac gtaatgtttc
      361 actttctaat gaagaattaa caactttgat caaagaagca attaaagaaa gcccaactgc
      421 tttcaatgct caatcaacac gcgcagttat ccttttcgga gatgcacatg aaaaactttg
      481 ggaaatcact gaagaagcac ttcgcccatt gactccagca gaagctttcc caaatacaca
      541 aaacaaatta gctggtttca aaaatggtta tggtacagta ttattcttca aagatactga
      601 cgtggtaaaa ggtctacaag aacaatttga attatatgca gacaacttcc cagattggtc
      661 agaacaatca aacggaatcg caacagctaa tacttgggta gcattagttg ataaaggatt
      721 gggcgcaaac ttgcaacatt acaacccagt tattgacgaa gcagttgcaa aagaatggaa
      781 tatcccttca aactggaaac tacgttcgca attagtattc ggttcaccag aaacaccggc
      841 tgaggaaaaa gaatacatga acgatgccga tcgcttccgc gtatttggat aattttattt
      901 gaaataaaaa acagaggttg tgacaaacat cttgtcgcaa cctctgtttt tattctggat
      961 caatcataat atcaatctct gcctcatcgt ttaagcgttg ggacaaaaat ggaactaatt
     1021 cttctaatga tgcagaaaat ttcagcatcg gtcctcgcca tccgtttcgg aaaaaattca
     1081 tttttacgat tttagaacct tttggctgat ataatacaat tttattgatc tcagaaaaag
     1141 gaacaccttt tttgtcaaag ctattcaaaa caagtccttc ttctgtgatt cctctactgt
     1201 ccaacaaaaa actaataaaa atcattgctg acaagatccc ttttgccaat tcatctgctg
     1261 taggatgact gatgagtgta taccaaatga ctagtgacac taagaagggt atcaccaagt
     1321 agacccatcg atttcgcaca gtccgataaa taatttcttt tcgaaccagc caaagaaata
     1381 aaaacatcac aacaacgaat aaaaacaata gaaccgtaaa gaatgttacc atgacaactc
     1441 gcctcgcttt ttcttctcca gaaaatagga aaagaatact gatttacctt ctcaaagaaa
     1501 ttggacttgc agcacgccgc acgtccaatt gttttcttta ttcaaatgta tcatattttg
     1561 caacaaccat gcttgctttt tcatctaata attcttggtc ctctgcagca cattgggcaa
     1621 ctttgaccac ggcgcagttt gtcatttttg atacaacttc accaatgacc gtttttgtaa
     1681 aaccaattgg tttgcatgca tattgttctc ctaaattaat catttcttcc gtcatcaaaa
     1741 tcctcctaaa ctgctggaac ttttctccac attaccactg ctatttcttt ggagatttaa
     1801 ctcattgatt tttatttaca gttaaaaatc aaccttacag gcattatagc gtactgtttt
     1861 cgttttcaca attaaaacag ctgttgtatt tagaagaatt tttttcaaaa aattaaaaca
     1921 tattccttaa aaactaatta tttcctacat attaaaatat aatacttcca tttccaataa
     1981 aaatacattt ataataggaa agataaacag ctgaaaaggg agatttcaaa tgaagaaaaa
     2041 aacgttcaaa aaactattgt ttctaggggg cacagctgct cttttattaa gcggtacaag
     2101 ttattaccta catatccatt ctccagaaca tacaatgaac actgcacaaa aaagttcaac
     2161 acaaaaaacg aaaaagacaa aagagaaagc agaagtttta ctagatgttc cattagagag
     2221 ccagtttgat tctccttctt tagaaaatgg ctgtgaagtc acttcgcttt ctatgctttt
     2281 atctttttat ggttatgaaa caactaaaaa ccagttagct gagcaattgg attacgtccc
     2341 tgttttcaat gcagatggga ctcatggcga tcctaatgaa ggatttgttg gtgatatcag
     2401 tggcggagac tgggctatgg tcgtctatgt tcccccagtt gcctcccttg ctcagcaaat
     2461 cgtccaaacg gattatcaca cttttccaaa aaccgatgct caactcgatg atatcaaaaa
     2521 agcactatct aaaggaaatc ctgtctggac ttctgtgact atcaattttg aagtcccaga
     2581 tgaaactgat tttatgactt ggaccacaaa taatggagaa gtaagagtca ctcctcttgt
     2641 tcatgcttgt gtagtcactg gatatgacaa agaaaatatt tatgtcaacg atccctatgg
     2701 tgtaaaaaat cgagcagtac cgatcaacga tttttcggcg attttcactg caatgggtgg
     2761 acagatgcta actttggaga aaagctagta attcaaacaa aaatccctta tactcaagat
     2821 accaaacctt tgaagggagc gtagataatg gaaaaattca cacataaaaa aatggatcca
     2881 aatgaaattc cgattatttt tgtccgtgac tgcaagggaa atgttcaagg taaagtctct
     2941 attaatgagt ggaacgagcg tcgcagacct gctaccctca atgaactgga aatcaaattg
     3001 tatcgtcaat ctcttgttta ttacgcagat caagagtacg agaaagccac cgatttattg
     3061 aaatttctaa ttgctcgaac agagtatact cgctttgaat atattgaacg tttagcaaac
     3121 atctatcata ttatgaatga acctgtcaaa gaatatcagt tattggacac cgtcttgtca
     3181 gtagcagaac tgattgccct tcctgctgga ttagaaaaga aactagtacg ccgcctttta
     3241 cgagtaaagc aacaactatc cgatcaagaa aaataacttg cgttttttta ggaaagtgct
     3301 atgattattt tgttgaataa atgggatgta gccaaactgg taaggcactt gactctgaat
     3361 caagcaattg taggttcgaa ccctgccatc ccaatttgat gtgcttgctg aaaaaatgaa
     3421 ccccctgtaa aagaacaatc tttttgcagg gggattattg tattattttt actacttgta
     3481 tttagtttac ataattaaat tatgaataat aaaatcgggc gtattcttaa tacaaaaact
     3541 gatttaccca ataattgcta atgctttctc cggaactttt tctctaggaa cttcctcata
     3601 cgtttctatg tgtgctcctt tattgctaat tttcaaataa tgattttctt ttaacacaga
     3661 aagaccatta aattcaaccg ttcgttcttt cccattggca tcagcagctt tctgcacata
     3721 ccttgctgta ccatattcat ttacttcctc tggtttttgt gtctttacat agacctctcc
     3781 tttttcaact aatggattta gctgatcaag tataccaggg atttctccat aacttccttc
     3841 agtataatat ttcagtccaa atagcaaaat accactaatc gccgccagtc caatcaaata
     3901 tttaatcact ttcatctttc tacctccttg ttatatattc agtatatggg tcagttaaag
     3961 aaattccatc cgtcccaagt tggagatttt tctcctactt tagaagcgag aatcgagtgt
     4021 ttttttagta aaaatgatcg ttatttgata ttattgacgt gtggataaat cagtttttct
     4081 cgttttgtcc atgtaaaaaa tcatgttgat agcaaaggat gtgttcaaaa tgaatcaaga
     4141 agaattattt caaaaagtca aggaaatgat taagaacggc aatttcgatg gcgcaaaacg
     4201 atttatcgaa gaacataaag aacaattagg accttataaa gagaaagccc aaaatctttt
     4261 aaaagatgta aatatcgaca gtgtcaaaaa caaatttaaa aatctattca aataagtaaa
     4321 actttcactt ttgtaaaatc aaaggaggac aatgctgctg catcgtcctc ctttggttct
     4381 tttctgaata cttcatacta aaataaacgt gtcggatcgt aatgataagt cacattgccg
     4441 ttcagtgagg cttttcccac cacatattta cgattctcca acttcagcca cgcttctcga
     4501 aaagccatta attcttctct ttttacatca atcttttcga tttttccatc gatcaaatct
     4561 tgaataagtt gttcatatgg attcattttt ttcctccatc tgctgtcaat caataagttg
     4621 taaaaatagg ttcatatgct tttttggtat ctagatcttc tctgactttg actgtcgtat
     4681 aaataatttt ttctactggg atactataat aacttccttc accattattg aatcggtgaa
     4741 cgtctttctt tgctaaaata ccatttattt tattcgtcag tacacgttgt tcgacactgt
     4801 tacttacaac atagtaaatc acccgaatat tattgatcaa atgcaaatcg atttctaaca
     4861 ctacatgatc catgaaaatc ccactccttc tttcactttg attatagcaa gtttctcctc
     4921 taatttcaaa atcgatacag attttaccgg ataaatccac aaaactgctt gcgccatttc
     4981 gcacaaagtg ttattttgta tcatggactt tatttatcgg aggcaatagt atgatcgcga
     5041 tcggtcaatt tgttttttat attccttttt ttattatgat aagcattctt ttctattaca
     5101 taaaatggac aaaaaagaag ttttcagttt tactggcctc tttacctgct gtatatttta
     5161 cttatcaaat tttttctttt aggcattggg aaacaacgtc tgtattaata acacacatca
     5221 tcgaattgac gctttcagta atttttctta ttatttggat c
//
LOCUS       DAZKCH010000123         5191 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000123 DAZKCH010000000
VERSION     DAZKCH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.127"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            137..748
                     /locus_tag="ACG84X_002640"
     CDS             137..748
                     /locus_tag="ACG84X_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9128448.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="ACG84X_002641"
     CDS             821..1750
                     /locus_tag="ACG84X_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HFP9128449.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1887..2645
                     /locus_tag="ACG84X_002642"
                     /pseudo
     CDS             1887..2645
                     /locus_tag="ACG84X_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
     gene            complement(2693..3895)
                     /locus_tag="ACG84X_002643"
     CDS             complement(2693..3895)
                     /locus_tag="ACG84X_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFP9128450.1"
                     /translation="MHRKEDFHMNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKT
                     ELTAFLDYEKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYR
                     RTNDTLEETVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERE
                     LHDRYAAIYMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEI
                     LIDLQERGVKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKE
                     VCDDFKMVYQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKT
                     IYSTNLIESFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTD
                     TLASMFTE"
     gene            3975..4499
                     /locus_tag="ACG84X_002644"
                     /pseudo
     CDS             3975..4499
                     /locus_tag="ACG84X_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4706..>5191)
                     /locus_tag="ACG84X_002645"
     CDS             complement(4706..>5191)
                     /locus_tag="ACG84X_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9128451.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
BASE COUNT         1641 a          879 c         1003 g         1668 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt catattggac atggtttggg
     3481 gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac
     3541 cttttcggaa gaggtgaatg acggtctcct ctaaggtatc attcgtccgt ctataagcag
     3601 gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg aatctggaga tgaagttccc
     3661 cgtactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac
     3721 caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat
     3781 tgacagcttt ttccaaatgg acacggaata attcattcaa atcgccttta ttcgctagag
     3841 tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt
     3901 gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa atattttaca
     3961 ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg gatgcgcata
     4021 tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag agatgccaag
     4081 cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc gatatcaaag
     4141 aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa cgtaaacaac
     4201 ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa atattggatg
     4261 agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt caacgattga
     4321 gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa cgtgttgtcc
     4381 gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg atggaaaagg
     4441 atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac gagatttagc
     4501 acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg cttcgctttt
     4561 tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa ggcaaaacat
     4621 cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc ctatggttct
     4681 taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac ttcgttttgt
     4741 aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat tctttgatat
     4801 ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag cagcagtgca
     4861 tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt tcgagttctt
     4921 tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt aaattttcta
     4981 cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata aatggagcat
     5041 ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc aaaaaggttt
     5101 ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga tacaagacag
     5161 ccgtcttgat ttgatcgatc gcttccttta a
//
LOCUS       DAZKCH010000124         5176 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000124 DAZKCH010000000
VERSION     DAZKCH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.128"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(136..1098)
                     /locus_tag="ACG84X_002646"
     CDS             complement(136..1098)
                     /locus_tag="ACG84X_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9128452.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1100..2539)
                     /locus_tag="ACG84X_002647"
     CDS             complement(1100..2539)
                     /locus_tag="ACG84X_002647"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFP9128453.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2724..4670
                     /locus_tag="ACG84X_002648"
     CDS             2724..4670
                     /locus_tag="ACG84X_002648"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFP9128454.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4934..>5176
                     /locus_tag="ACG84X_002649"
     CDS             4934..>5176
                     /locus_tag="ACG84X_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9128455.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         1666 a          878 c          855 g         1777 t
ORIGIN      
        1 tttctccact ccaaaaaagt ctaacttttg ggggtcacta caagttgaca actccttttt
       61 gtttacaaat caattggata tctacaaatt gtattttcta acgaatttta tagacattaa
      121 aaaattaatt taacgttaaa tacttcctcc agaaagtatt gagattggta aaatataatc
      181 cttatttgtc ttttcgcctt taattttttt cagaagaata tcaacaataa gacttgcaat
      241 ttcatcaatt ggttgtctta ttgttgtcaa ttgtgggaaa aatttctcaa taaaagaggt
      301 accatcgtat ccaataattt ttaaatcttc tgggatatta agtttaagtt gatgagcaat
      361 tttcatagtg agaatggctg ttaaatcatc agaaacaaaa ataccatctg gtttgtgatt
      421 tataatagtt gactttattt ccatttcacg acggatagta gacagattat taggaatttt
      481 gaaaattttt ccatttggat tttgaaaaga aaaacctagt gcacgtaatt ctgtgggaga
      541 atccgtgtta tcatttcctg taatcataat ggtattttga caaccatttt tttgtaaagt
      601 cttagctgca agttttcccc cttcaaagtt atctgaagaa acaatggaaa cattaggagc
      661 taaatttcta tcaaaagcaa caataggtgc tctcacacgc tcataatcag caattccaag
      721 attatggctt gatgagatta tgccatcaac ttggttggct tcaagcattt caatgtattc
      781 tctctcttta gcaggatcat tttgactatt gcaaataatc gttttatatc catgtttaaa
      841 taactctatt tcgagatact caatgagttc agagtaaaag atattactaa tattaggaaa
      901 aataagacca ataagctgag gtgactttcc ttgaagtcca cgtgctaaat tatttggttt
      961 ataaccaaga gttttcatag cttcatgaac tttttgtttt gttttttctg ataaatatcc
     1021 cttattatta atgacgcgtg aaacggttgt tgggctaact ccagctaatt cagcgacatc
     1081 agttaatttt gctaccattt taatatttta attcaaagta ttttccagta ggttcgcctg
     1141 atttgatttg aataccattt tggtgatttt cagggaatac acgactagta aacacttttt
     1201 ctcctttatt aataaaaatc tcaatgattg agttatctac aaaaatgtta gcagttgttt
     1261 ctttagtatc aattgagcat tcacgaatcg taccaaagtc agtggcatat tgaatgcctg
     1321 ctttgctgcg atctaaaata atttttcctt ctttggtatc tacaatcaag ctaagtccat
     1381 ttcctttact atcagagaaa agaagtaact ccgatttctg atttggagga aaagttagtt
     1441 caagctcata agtattattt gtttctgctt ttgctgtaaa ttgttcagaa ctagcacgta
     1501 atgatgtaat agcttctact ggatattggt aaagtttacc atcttttatt gaaagttctt
     1561 ttacaagact cattgctccc tgataatcat acttatcagt tggataatcg atatcaggta
     1621 gtccaatcca actgacaatc agagcacgac catcaggagt attgaatcct tgagtcgcat
     1681 acgcttcaaa tccataatca agattttgaa tttctgaagc gcccacaagt tttacttttt
     1741 ctatgtcaag cgattgacag atcttaaaag tattcggata gatattccca taatttagct
     1801 cagatttatc caacccttga ggacaataaa tgagaacagg ttttttgtct acaaatacta
     1861 gatttggaca ctcaatcatg tattctgaac cagtgccgcc aaaatcaagg ttgccaactt
     1921 cctcccatgt ttccacgtta ttgtcatccg ctttgtaaag tttgataaag cctgattttt
     1981 ctaaattttg tgctccaaca atcgcataca attgtccttc ataattaaac atttgtggat
     2041 cacgaaaatg atcagttaca tcagcaggtt tatgaataag aacattctca cctttcgtaa
     2101 tgttgtagtc tttatccatc catgctccga tttgaagtgt atcacgttcc caattttcat
     2161 ttcgaacgtt tcctgtatag agtaagaata gattcccctc tatttcatat gcagaaccgg
     2221 aataagcgcc gtggctatct cgttttgtgt ctggaagaag ttctgctcct gttacatgaa
     2281 aatgaactaa atcatctgat tcattgtgta cccattcttt caacccatga gcagctccaa
     2341 atggccaatt ttgataaaaa agcgtatatt ttccgttaaa aaaagaaaaa ccattaggat
     2401 cgtttaacaa tcctgtttta ggttcgatat gatagctagc acgccaaggt gatcgtttta
     2461 cattatcctt aattttatcc atctcatctt tagtccaatc agaataagca cgatatcgta
     2521 tttctcgagg taagttcata ttttactcct tcaatttatc tttttacaac tagtatggta
     2581 aacgttttcc gttgaaaaat caatcatttc atttaaaaaa ataaactata tgacaaacgt
     2641 ttgacatatt tttaagatat gctaaaataa atttgcattt cagtgaaccg ttttcacgta
     2701 aaaataaaaa aggagtgatt cgaatgaatt acagtaaagt agcttccgac gtaatacaag
     2761 cggtcggaaa agataacctt attgcagctg cacactgcgc tacacgtctt cgtctcgtac
     2821 taaaagatga cacgaaagtg aatcaaaaag ctttagacga aaatccagat gtgaaaggca
     2881 catttaaaat tgatggacaa tatcaagtga ttatcggtgc aggtgatgtt aatttcgttt
     2941 atgacgaact tatcaaaaaa actggacttt cggaaatttc aacagatgat ttaaaacaaa
     3001 ttgctagtaa agataaaaaa ttcaacccca ttatggcatt aattaaatta ttatcagata
     3061 tttttgttcc aattatacct gcccttgttg caggtggttt attaatggca ttacaaaact
     3121 ttttaacagc tgctggactt tttggaccaa aatcaattga agaaatgtat cctgcgattg
     3181 aaggtatttc ctcaatgatc caactgatgt ccgctgcacc attcatgttc ttaccaattt
     3241 tagtaggtat ttcagctgct aaacgttttg gagcaaacca atttcttggt gctgcaattg
     3301 gtatgatcat gacaacacca gatcttggtg gctcaactga atattggaat atttttggtt
     3361 atcatgtttc acaaacaaac tatgcttatc aagttattcc agttttagca gctgtttgga
     3421 tattatctat attagaaaaa ttctttcata aaaaattgcc atcatctatt gactttacat
     3481 tcacgccatt attatcagta atgattactg gatttttgac tttcacagtt attggccctg
     3541 taatgttatt gttgtctaat ggaattacag acattattgt ttggctatat aacactactg
     3601 gatttattgg aatgggtatt tttggaggaa catattcact tatagtcatg actggtttac
     3661 atcaatcatt tccagctatt gaaactcaat tactttcagc gtggacaaat ggtatcggac
     3721 atggagactt tatctttgta gttgcatcta tggcaaacgt tgctcaaggt gctgcaacat
     3781 ttgccatttg gttcttaact aaaaattcta agacaaaaag tcttgcttcc tctgcgggtg
     3841 tctcagcact tcttggaatt acagagcctg ccttgttcgg agttaactta aaataccgct
     3901 ttccattctt ttgtgcttta attggttcag gaattgctac agcagtagca ggattactta
     3961 aagtagttgc tgtttcactt ggttcagcag gtttcttggg atttctttca attaatgcaa
     4021 catctattcc attttacgta ttgtgtgaat tgattagctt tgtagttgct tttgcaatta
     4081 cttacttcta cggtaaaaca aaagctgctg gtatctttaa agcagaagaa attgctgaac
     4141 aaacaccagt taattcttca aaagtagcaa caacagatcc aatatctact gatgttgaat
     4201 caacacaaac aaaagtttca tcagaaacaa ttgttagtcc catttctggt aaagtgatta
     4261 gtctttcttc agtaaatgat ccagtctttt catcagaagc tatgggaaaa gggattgcca
     4321 ttaaaccaaa tggaaacacg gtccattctc cagtagatgg tactattcaa ctcacgtttg
     4381 aaactggaca tgcttatggt attaaatcaa ataatggtgc tgaagttcta attcatattg
     4441 gtattgatac tgtatcaatg ggaggaaaag gatttacaca aaaagttact actaatcaaa
     4501 aagttagaaa aggcgatatt cttggagcat ttgaccgttc aatgattgag aaagaaggtc
     4561 ttgatgatac aacaatgatt attgtgacca atacttcgga ttattcagaa gtaaatatag
     4621 tagctgaaaa tacagtcact gagggtactg atttacttga aatcaaataa atatatttcc
     4681 ctgagtaaag atggaatttt ctttccaaaa tcaaataata tagattaatc aaatatttga
     4741 gaataacatt ttatttaatc ttttcatata tcaattgtat gaaaaattat tagaatttta
     4801 aaaaatgata aaaattcaaa aagaaaaaat agtagttatt tacttgtcat gttactaaat
     4861 aaaaaaataa tttaaatatg atatatagtc atttatttag tgatttcatt ctaaaataaa
     4921 gggagaaatg tctatgctat acggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc
     4981 cattggcgat gaagaaatga cgatcaagga aagagtgagc tttccgacaa cgacacctga
     5041 ggaaacaatg cctttagtca ttgacttctt caaacaatac caagcagatt tagcagggat
     5101 tgggattggc tcatttgggc ctatcgatat ccatcgcgat tccgccactt atgggtacat
     5161 tacctcgacc ccgaaa
//
LOCUS       DAZKCH010000125         5037 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000125 DAZKCH010000000
VERSION     DAZKCH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.130"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..347)
                     /locus_tag="ACG84X_002650"
     CDS             complement(<1..347)
                     /locus_tag="ACG84X_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFP9128456.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFA"
     gene            complement(654..1751)
                     /locus_tag="ACG84X_002651"
     CDS             complement(654..1751)
                     /locus_tag="ACG84X_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFP9128457.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            complement(1859..3886)
                     /locus_tag="ACG84X_002652"
     CDS             complement(1859..3886)
                     /locus_tag="ACG84X_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFP9128458.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            complement(4031..4759)
                     /locus_tag="ACG84X_002653"
     CDS             complement(4031..4759)
                     /locus_tag="ACG84X_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFP9128459.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
BASE COUNT         1426 a         1025 c          803 g         1783 t
ORIGIN      
        1 gcaaaatttt ctactgagat atatttttcc tgaaagaaag ccaataccat tttcatagat
       61 aaagaatccg ttatataacg agataacaga gctttgctag aacattttcc attaatttcc
      121 agacatatat ccaattcact gacggttact cgcaaatttt tctctagatc gaacttttgt
      181 aaatcatgtt tcagcttatc gatcgttttt ttcaagagaa atgtcgatag cgacaactct
      241 tcttgaacat tcgatattga ctctgataaa tttgagcttg cttctaaata tttaagtaat
      301 gaataacttc tgtgatcttc tttgcttaaa aaaaactcat aattcattag tcatcagctc
      361 tttctacgta tattactttc catgcattca ccaactagct ggggataaaa ctgatttcct
      421 ggatccgagt cactgttgtc agcgattctt gtttgtataa tatacatcgt cctgtctttt
      481 ttttaacatt ttggagagcg ttttatttgg cctttctcgc gatcaaacct gttattagaa
      541 ttatatcatt tactagtatg catttttatt aataaaatgg tatattttat attgttataa
      601 aaagagccca accatcctac aataataaaa atttactatt tgttatctta accttacttt
      661 tctttctctt ctttttttct caaaacaaac aaaagtatgc ataataaaat aaacaataag
      721 aaaagtgaag ctactaagat ataaatccaa ttattgtctt ttttaatcgt aacatccgtc
      781 gtgttcaatt ccttggctac ttttccgtct attgtaaaat ctttttcaaa tacccattga
      841 ttggtatagt tgatcgtagt atttcctttt tttctcgaaa attttccatt ttcattttca
      901 tttcctaaaa cagtcattgt aaggtgatat tcacctgggg ttagcggttg accatttaaa
      961 gcagttggaa aagaaaaatt tgtattcggc gcaatctgca atccttcttt ttcctcttga
     1021 tataaaactt cagaatgtcc tttttttgta atttttgttt caataactac ttgattgata
     1081 taggtttttt gatcattttg aacgtttgct aagatgacat ttcttgcatt gatttgatct
     1141 ggtttaactt catgaagagt aaggttcgga gcaacttcgt tcagtgtctg ttgcatcaac
     1201 aaagcaataa tataggtgta ttcattctca atcgataagc tttgatcctt agtttctgtt
     1261 tggtcctttt ccgtctggat ttcttggaat gtgatcccac cagccaatac accatcaaat
     1321 cgctcattcg gcatcctgac atgaaaagca acggtttgga cacttttagg ttttagcgtc
     1381 actatctgtg gatagctcac ataatctacc agatcaaaga tcaggctcat gtctttttca
     1441 atctcgtttt ttccgtattc aaccatcaca tttgaattgg tggttgcgct attcacagaa
     1501 atatcgattt tcacttcttt ttctgtatca tttctcaatt ccgcttttac ttctacttcc
     1561 tgatccggat caagttgaag atcgaagtaa gtttttctct tgtcgatttg attctctgaa
     1621 gttatcggcg tcactgaaaa attaaatgca ctagctgaca ctgatatatt gttaaaaagt
     1681 gcccctaaaa taactaggag tgttataaat aattgttgtt ttggtctcaa gaaaatcgct
     1741 cctttaatca tatgtaagag aagactataa caaaatcttg tctctgtggg acacaagagc
     1801 ctatggtacc tgtgcccttc ttgaaactca ataattttgt tatattcttc tcttcctgtt
     1861 aatttcctgg gacatctgca agtatccaag atagtttccc ctcaaaggtt ccgattcttt
     1921 ggttttctac aggaatattt attctgattc cacgatgagc tgtagaatct aaaagagagg
     1981 acaaatcgct ttcacccttt tgatcacttt cgaaaatcgt aacagcggat gtccctataa
     2041 ccgttgtatt ttcagaggta acaaaggaaa gagcttctgg aagctcaaaa tctccatttg
     2101 taagaacttt ctcttgtttc aattgtaatt tccaacttcc aaaagcccgt tcatctataa
     2161 ttttcaaccc acctgaaaac tgtccgaatt cacttaatgg tctactggat attttatgtt
     2221 ttccaaaatt gacatattga ggagcagttg agagataaag tttgcctttt ctgtaataaa
     2281 aatagatatc ctctgtattt tcggagaaga tgccttctgt attcgctgaa tccgagtcaa
     2341 aaacataccc ttcaatatca ataggagttt ctttatactt ctctcctatt ttcccagtga
     2401 ttgttttcat ttcagcaata tcaatctgac tgtctttatc tttataataa acatggatat
     2461 ctatctcctt cagctttgcg atctttaggt ttatttcatt cgattgctca atcaaattcc
     2521 cgttttcaag gtattcaaaa tgcatagtga gtactttttc aggaattact tcctgcaaag
     2581 ttgtctccaa ttcgattatt aacgtatctc cagcaataaa ataatctgtc agatttagcg
     2641 tgactcgatt tccggttatc aagatatctt tggcatcaat ttgatttcca ttgatcaaga
     2701 tatgctcggg aatagttaat tcttgtggga ggtcgatact agtctgcatt ttcttatatt
     2761 caagaaaatc cccctcgacc ttcaatgtat ttctgatagt tatcttatcg tttcctccag
     2821 cttcagcgat ggccccataa tcactatcgt tgacttttac atcagctgtt gatgtgacat
     2881 tcgatggaag tcgcgtgaca gcgacagcat tttcttgaaa aaaagtacct gttgaagaag
     2941 taaaccccca atttacttct gtagaaccaa actgcctaat gagatcaggt ataatccgag
     3001 aagagcgacc gacaccttcc aaatcataag taagacttct ttgctccgcg tcccatttaa
     3061 ttattaacaa gcgccatgtg ccattagaaa gaaatgtagg agctaccgtc acgccagtat
     3121 gctctccaga ataattatta ttatttggtt taggcgtgac aaaagcgaca tgtccatgcc
     3181 ctctattatc agcagttatc tctcgatcca ttcgatcaga agaaccacta tttttatacg
     3241 tatcaaactc aatcgagagc gcattcgcaa tgtaaggttg gccagaacga gtagaatatg
     3301 agccaattcc catacctggc gatccaataa cttgactggg attactagcc attctaggat
     3361 cgccagtcaa tgtaaaggtc atgccatctc ccgctctatc tcgttgattt cctaagtata
     3421 aataagattt aaatgtaaaa tccgagagta aactaatctt cttatttgac caaatagctc
     3481 ctctttgaga cctttctgct gggttcaact gcagtaactt cccattttcc aatatggacg
     3541 tgctagtacc gataggtgtt tgaaaaattt tatcgataga aataatattg ggatcgtcag
     3601 gcagctcaac cgcagaaatt ggtgcatctt ctagtccttg tttgtccgaa ccctcagctt
     3661 ctacgttgtc agtggtctct ccactactcg aaatacttaa atcctcactg ctttcttgtg
     3721 tctggttgga ttctattaaa ctgtcgaatg tcgaagtgag tttgctttct tcgtctcttc
     3781 tatttccatg ctccaactga ttcaattcca aagagtaccc tatgatcgga aagatattag
     3841 tcactaagag actgcttaaa atgagcacga tcctcctctt tttcaatata tcttttcctc
     3901 ctgatcgtta aattcctaga tgaactattc gtatccaaac aaatttagcc tagcctttga
     3961 caatttttgc tcgattacct cgcaagacaa tatgactacg tatttatttt taacagttct
     4021 tttcagtaaa ctagttgtta ggtgtatctt ctaatgtcca aactaattta gtggaatatt
     4081 gttgcgctaa cttgacagat ttaccgggta ccgaaagctg taccgcatct tgattttcat
     4141 tttcatttgc accaaatcga tagacccaag tccccacacc tgttcctgat ttagcattaa
     4201 ttgctaacgt attgtttcct cccggtgtca acgttaattc agaattcacc gtttgcggcg
     4261 tatatgttgg atcaaccaaa gaaacagcct gccctttcgt aaatttcagc tgtgctccaa
     4321 ctagttcatc cccactggca gttttaaact gttctggttg agagacactt aatttccacc
     4381 cagataaggt acttctccta tctgtcactt ggacatatgt cggttttcta gacccatcgt
     4441 tcatcacatc agcagctgca taatacgttt tatccgcagt agaaattttt tgagtcccaa
     4501 atttgaattt tgatccataa tcaatcgata atgcccctcc tgttccaggg cttggaggat
     4561 ctgatggatc gacaggttta ttgggatcag gattctctgg atcaacagga ggagttacac
     4621 cctcatctcc tgcttcaaat gtaatcgttc cttctgtgtt atattccttt gggtatactt
     4681 cagttgcaga aacaaaagtc gtacttgcta ccatgctgaa taacatcatt gctgctgtta
     4741 atacgatttc ttttttcatc attgacattc ctctttcttt atttactaaa catatcagtc
     4801 gattggatta atccatagca aaattctgtt ttacgatact tatgaaataa aagaacatag
     4861 acctatattt ggtcctatgt atcgattagt tataaatgat tatcagcccg atttgatttc
     4921 tagtttttat tgcaacttga tgcaaacaca atctagaaat acagctgtca tagcctttaa
     4981 aataattcgt aagtccccct cctatctatc aaaatgtgac ttgacgagag tgtaaaa
//
LOCUS       DAZKCH010000126         4997 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000126 DAZKCH010000000
VERSION     DAZKCH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4997
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.131"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(229..1719)
                     /locus_tag="ACG84X_002654"
     CDS             complement(229..1719)
                     /locus_tag="ACG84X_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFP9128460.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            complement(1762..2061)
                     /locus_tag="ACG84X_002655"
     CDS             complement(1762..2061)
                     /locus_tag="ACG84X_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128461.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            complement(2427..2711)
                     /locus_tag="ACG84X_002656"
     CDS             complement(2427..2711)
                     /locus_tag="ACG84X_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9128462.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            complement(3230..3715)
                     /gene="vanZ-A"
                     /locus_tag="ACG84X_002657"
     CDS             complement(3230..3715)
                     /gene="vanZ-A"
                     /locus_tag="ACG84X_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFP9128463.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3868..4779)
                     /locus_tag="ACG84X_002658"
     CDS             complement(3868..4779)
                     /locus_tag="ACG84X_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFP9128464.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         1486 a          939 c          727 g         1845 t
ORIGIN      
        1 aatcaagtgt tcgcttcgct ctcactgccc ctcgacgttt tagtagcctt tccctcactt
       61 cgttcagtcc aagccaacta aaagttttcg ggctactctc tccttctccc cctaataatt
      121 aattaaaatc ttactctgta tatttctgct aatcattcgc taaacagcaa agaaaaaaca
      181 aacacgtatc atagatataa atgtaatggc atagtgcggg ttttattttc agcctgtatc
      241 atagctaaac aaatcgagtt gtgtgtccgt tttagggcgt tctgctagct tgtttaaagt
      301 ctcttgaatg aatgtatgct ctaagtcaaa agaatttgtc agcgccttta tatagctttc
      361 tttttcttct ttttttactt taatgatcga tagcaacaat gatttaacac tagcaagttg
      421 aatgccacca tttcttcctg gtttaatctt aaagaaaatt tcctgattcg ccttcagtac
      481 cttcagcaat ttatctaatg tccgttcagg aatgcctagc acttctctaa tctctttttt
      541 ggtcgtcact aaataaggct tgtatacatc gcttttttcg ctaatataag ccattaaatc
      601 ttctttccat tctgacaaat gaacacgttg acgttcgctt ctttttttct tgaatttaaa
      661 ccacccttga cggacaaata aatctttact ggttaaatca cttgataccc aagctttgca
      721 aagaatggta atgtattccc tattagcccc ttgatagttt tctgaatagg cacttctaac
      781 aattttgatt acttcttttt cttctaaggg ttgatctaat cgattattaa actcaaacat
      841 attatattcg cacgtttcga ttgaatagcc tgaactaaag taggctaaag agagggtaaa
      901 catgacgtta ttacgcccta ttaaaccctt ttctcctgaa aatttcgttt cgtgcaataa
      961 gagattaaac cagggttcat ctacttgttt tttgccttct gtaccgctta aaaccgttag
     1021 acttgaacga gtaaagccct tattatctgt ttgtttgaaa gaccaatctt gccattcttt
     1081 gaaagaataa cggtaattag gatcaaaaaa ttctacattg tccgttcttg gtatgcgagc
     1141 aataccaaaa tgattacacg ttagatcaac tggcaaagac tttccaaaat attctcggat
     1201 attttgcgaa attattttgg ctgctttgac agatttaaat tctgattttg aagtcacata
     1261 gactggcgtt tctaaaacaa aatatgcttg ataaccttta tcagatttga taatcatagt
     1321 aggcataaaa cctaaatcaa tagcggttgt taaaatatcg cttgctgaaa tagtttcttt
     1381 tgccgtgtga atatcaaaat caataaagaa ggtattgatt tgtcttaaat tgttttcaga
     1441 atgtcctttc gtgtatgaac ggttttcgtc tgcatacgtt ccataacgat aaacgttggg
     1501 tgtccaatgt gtaaatgtat cttgattttc ttgaatcgct tcctcggaag tcagaacaac
     1561 accacgaccg ccaatcatgc ttgattttga gcgatacgca aaaatagccc ctttgctttt
     1621 acctggcttg gtagtgattg agcgaatttt actattttta aatttgtact ttaacaagcc
     1681 gtcatgaagc acagtttcta caacaaaagg gatattcatt cagctgttct cctttcctat
     1741 aaatcctata aaataggttg tttaattaac ttggtttgct ttttcattca actgtttcaa
     1801 tattgcatgt tttgaaaaag atttttttcc tttataagtc aatttttttc cactaatcga
     1861 ataaattatt ttgttatttt ctattaactt atatatataa tcttccccct ccgaagaaaa
     1921 atacttatct gattttgttt ctaagtagat atttctcttt tctaactctt tcttaaacgt
     1981 ttctagtgta tagatatttg ctaattttct tatctccaat aaactatttt ttatataagt
     2041 tttacattca tcatgattca tacaaactcc accttctata aatgaataca aaaaaagcaa
     2101 tcaaacgatt tccgattgat tgcttaacaa ttcttaaatt cagtagctta gatacttgaa
     2161 aactctctga tttccctata taatgatagt acggttatat accgtcttca aacaaagtta
     2221 attaaataac ttcttacgag ggaagagttc atctgactaa ctgataagcg ttggtttggc
     2281 aatcttatcg ggctatgcat ttataaaatg tcgtcaaaca ttttataaat gtgtcatggc
     2341 tcttttttcg tttctattca gttcgttgtt tcgttatatc tagtataccg cttttaaaaa
     2401 aaataagcaa cgatttcgtg cattattcac acgaagtcat tgcttttttc ttcttccatt
     2461 tctaaatcca atgttacttg ttctgattct gtttctggtt ctggttctgt tggctcattt
     2521 gggattaaat ccactactag cgttgagtta gttaactttg caatttgttc tagtgttttt
     2581 atggttggat ctgattttcc tgattctatt cgtgaataat ttgatctact catttctaat
     2641 tcttgggaga atttttcttt tgatttggta cctctcatct tttttaagct ttctctaaat
     2701 gctagttcca agtttctccc ccctcttttt gtgtaataaa attcacgctt tatttaaatt
     2761 atagctttta atatcttaat aaacaagtga ttaatcactt gtgatttgtg attattccaa
     2821 aagtaggtaa tttcaccaac ctttttcaaa agtttttatc gacgattatt ggactggatc
     2881 gtgtttccta aagcgattct aagcgcatgt ttaattttaa agtgggtaat tctctttaaa
     2941 acgtcctaca aagattcaaa aaaagcatgg ctgctagtgg gggtaccgtc aggaaaatgc
     3001 ggatttacaa cgttaaggaa atttattaaa gagaccaatt cctcagcact aaaattgata
     3061 attgggcttt ctttgttact atagtgttag gtaagctttt tactttatca ccggttttcc
     3121 cctcacttca cacctacggg cgagtttccc cacatcccgt tttccatcta atccaattca
     3181 ttcaatatct ttatgtgtat gaaagatcag attgcttgat ttagacatct tacacgtaat
     3241 ttattcttaa atgggtacgg taaacgagca ataatacgag caaaagtata cctacaaaaa
     3301 taataactct gtctaatttt ttttgattca tatgcttatt gcttaaacca tataatttca
     3361 gtccaagaaa gcctccaaca gtatttgtaa ttacatctgt tatgtctgtc gctccaatag
     3421 cgaagataaa ttgaattatt tcaaaagtaa gacttaaaac cagtacaaaa gcaaacttag
     3481 gtaaaaatcc gatttcttta aaattgacat tcaaaagcaa gccaaatgga ataaagatta
     3541 taacattatc tatcatctct ctgaaattcc cagtagcagt aaatggagtc aagttaagac
     3601 ttctttgatg ataattaaat actgataaaa tattgtattg taatttgaat aacactaacc
     3661 agattagtgt cactaaatat aaagctagca atcctctaga taatattttt cccaatataa
     3721 tttcctctaa ttcttttgtt taagttgtat cattagtata gcaatgtcct agttaacgtg
     3781 ggttttaaat taaaaagcta acgttacccc aaaagtgcta gtacaataat gctgttcatt
     3841 aatttcgttg gtttcattcc gccatcctta cctccttgaa ttagtatgtg ttgatccggg
     3901 aaacactgtc acaattacac cgtctatatt gtttcctgat atctcataac gaagattagt
     3961 cggcacatga atggtggtat ttttagtaac aggataataa aagatctcat atttttcccc
     4021 atttacacta acagaaatgg ttttttcttc ttttaggtaa tccatatatt cctcgagaac
     4081 gaaattcttt tctttcataa tcgcactatg tggtaaacca acatagcgaa tatgccatgg
     4141 ttcatattga attcctgtta actctgtttt gtcctctgga taacgtaaaa tgaacccgta
     4201 tttccaagca ttttcttcta tccactttcc ttcaggggct cgttccattt tcgtcaagct
     4261 tgatcctaca tctagtgata aacctgaatt atgctcacta taacctgctg gtaaggcata
     4321 ctcagccccc atttcttggt aaagcacact ttgctcatca aagtctcgat agccactatt
     4381 aataataaaa tgactaacgc caccctttac agcatcattg accatctctg aaaatttttg
     4441 tgctatttct tttgacatat aaatattact atcaagcaac ccgtatccat ttattaattc
     4501 gtcatgttta gataaattca cgatatctga cttcacactt tcttggcgaa caggatattt
     4561 actattgatt aatagcagat ttccttgata aacctgttct tctgtaattg ttttctcttg
     4621 ggtattttca gaagtcccac tattttctaa atgttctttg ggattttgat cataattttg
     4681 aaattcgact ttttcctgag aaaacagtgc ttcattaacg tagtcataac ctaagtatat
     4741 taagaataac aataacaata aaaaaaacaa cttcttcatt ttcagtctcc tccttaacta
     4801 tatagttgga agtatgaaat atttctagaa tcttcccctt aaacggcaca atctcgtttg
     4861 agattgtgcc gttttgcccc gtaaattaca gtcaattatt tcgccctact ggatttacta
     4921 ttatcaccaa tgtagatgaa ttttcataag tgatacccat gctgaattta acgaggctga
     4981 actgcctgtt gacaatg
//
LOCUS       DAZKCH010000127         4948 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000127 DAZKCH010000000
VERSION     DAZKCH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.132"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACG84X_002659"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="ACG84X_002659"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFP9128465.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="ACG84X_002660"
     CDS             complement(1297..2133)
                     /locus_tag="ACG84X_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128466.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="ACG84X_002661"
     CDS             complement(2317..3534)
                     /locus_tag="ACG84X_002661"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFP9128467.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3844)
                     /locus_tag="ACG84X_002662"
     CDS             complement(3683..3844)
                     /locus_tag="ACG84X_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128468.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3917..4000
                     /locus_tag="ACG84X_002663"
     tRNA            3917..4000
                     /locus_tag="ACG84X_002663"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4948)
                     /locus_tag="ACG84X_002664"
                     /pseudo
     CDS             complement(4240..4948)
                     /locus_tag="ACG84X_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1514 a         1024 c          794 g         1616 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtca
//
LOCUS       DAZKCH010000128         4947 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000128 DAZKCH010000000
VERSION     DAZKCH010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.133"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            128..1771
                     /locus_tag="ACG84X_002665"
     CDS             128..1771
                     /locus_tag="ACG84X_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFP9128469.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(1844..2389)
                     /locus_tag="ACG84X_002666"
     CDS             complement(1844..2389)
                     /locus_tag="ACG84X_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFP9128470.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(2412..2897)
                     /locus_tag="ACG84X_002667"
     CDS             complement(2412..2897)
                     /locus_tag="ACG84X_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFP9128471.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(2887..3699)
                     /locus_tag="ACG84X_002668"
     CDS             complement(2887..3699)
                     /locus_tag="ACG84X_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFP9128472.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(3838..>4947)
                     /locus_tag="ACG84X_002669"
     CDS             complement(3838..>4947)
                     /locus_tag="ACG84X_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFP9128473.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         1593 a          977 c          946 g         1431 t
ORIGIN      
        1 aaaataaagc tcaacgaacg cacttagcag attcgttgag cttttcgttt ctagttaccg
       61 gtaacaagga tacttctaaa atagaatcgg ttataatcaa gagggaccgt taaaggagtg
      121 aaacgatatg atacaagaac aaaaatggtg gaaagaagca gtaggctatc aaatctatcc
      181 tgctagtttc aaagatagca atggcgatgg tcaaggagac atcaatggga tccgtgaaaa
      241 acttaattat ttgaaagatc ttggtatcgg ctttatctgg atcaatccga tctatcaatc
      301 tccatttgtc gataatggtt atgacgtaag tgactatcaa gatatagaag agagattcgg
      361 aacgatggaa gattttgatt tattgctaaa agaagcacat gaattaggga tcaaagtgat
      421 tatggatctt gtcatcaacc atagttcgga tcagcatcaa tggtttgaag aatcgaaaaa
      481 atctaaagaa agcccgtatc gcgattatta catttgggtc gacggggtag atggcaaaga
      541 accgaataat tggacatcga ttttcggcgg ttctgcttgg gagtattctc atgaaactgg
      601 acagtattat ctgcatgttt ttgcaaaaga acaaccagac ttaaattggg aaagcgagaa
      661 attgaaagaa gaactattca atatgatccg atggtggttg gataaaggga tagatggatt
      721 tcgtttagat gcgatttctc atgtaaaaaa agatgaatat tcagtaaaag ccacagagaa
      781 ccctttctca ccctttcaaa atgtctcagg aatcgaagaa catttgaccg atttgaaaca
      841 tgtttttgaa gagtacgata tcatgactgt cggagaagca agtggtgtca ctgcagaaga
      901 aggaccacaa tgggtaggga aagacggtta tttcgatatg atattcgaat ttgatcatat
      961 ccatatctgg cagcaagaaa aagaagggca attagatgtc cttaaattga aacttgcatt
     1021 aagcgcttgg caaacttcat tggatggtat cggatggaac gctttatata tggaaaacca
     1081 tgatgttcct cgtgccgttt cagtgtttgg agatactcgt cccgattttt gggctatgtc
     1141 tgcaaaagca atcgctatga tgtatttctt tttgcaaggt acgccattta tttatcaagg
     1201 acaggaaatc ggaatgacga atatgccctt tgaatcgatc gatcaagttg atgcagtaga
     1261 ttcgaaaaga ctttataaaa ggctgcttgc ggaaggtaag acaagagaag aagcattgga
     1321 tatcattcgt gaaacaacga gagacaacag caggacaccc atgcaatgga cttcggaaca
     1381 atatgctggt ttttctacac atgaaccttg gctgatcact aatccaaata ccaaaacgat
     1441 caatgtagaa caacaagaat atgaaccaga gtcggtcctg caattctata agaacatgat
     1501 ccgcattaga caaaccaata aaggtctgat atacggttct tataaagaat atcttcatga
     1561 acatccacaa ctttatgtct atgaaagata tttagaagat gaacaatatc ttattatggt
     1621 aaacttaaca gaatcacttg ctgactatga acttccaaaa gaagcagatc agtcctggac
     1681 attactcttg tcaaattcct ctagcggaga atttgaagct aaaggcatac tagcacctta
     1741 tgaagctcgg ttatataaaa caaacaagta aaacttcctc gttaaagttc attagttgga
     1801 ctttgcgagg aagtttttca gattgctctg tcaattactc atttcaataa ttcgctctag
     1861 gaccaccgat atatttagga cgagagcgaa gggctgtcac gtgagcttgt ccaagggttt
     1921 tcaaacgagg tctgacaggt acttggacat gtttgatatg cataccgatt gatgtgtcac
     1981 cgatatcgat accggcttgt ccaactacgt gttccacttc gacaggatca ttgaactggt
     2041 caaaagcagc aacagaacaa gcacctccag catgtagtgc aggaacaaca gagacaattt
     2101 cgaaattttt tgcttctgcc actgttcgtt ctactactaa tgctcggttc aaatgttcac
     2161 aaccttggac agctagcgca atttctttag gatccaacaa ctcttttaac gtacggatga
     2221 tccattgacc aacttccgca ctggaatttt ttccaatatg tcctccaacg acttcgcttg
     2281 tgctgcatcc taaaacaaaa agatcacctt ttttcaagtg tgcctcagcc aatatgtcat
     2341 taactatttc agtcaattgg tcttttaatt ctttttctga caacttcatt ttctaaaacc
     2401 ttctttttca attaatattg cttccgtgct tgaatacgtt gaagacttgc agttatagga
     2461 aaggcaagtc ccattccaat cagattttgg aagatgtttc ctggtataga agccactcca
     2521 gccggccaat catataaaat ccaaccggcg ataccatagc cgatgatcat aactaagctt
     2581 cctaataaaa gccctaatcc ccacatacga gtagaagatt tgctgaaaga accagcaaca
     2641 tatccttgta acccgtggat cactaatgaa aaaactgccc actgcggata tcctgaaatc
     2701 aaatcgatca atagaccact ggaagcacca acaactaatc cacccgttgg accataaaga
     2761 aaagcagcgg tatagatccc ggcctcgcat aatgtcacaa atccattcgt agccggtaca
     2821 gggatcaaaa ttgttaatga aagggcaact gtcaacgcaa tcagcatagc atagatcgtt
     2881 aattgcttag ttttcatttc tcattcctcc tttttgaata ccgccagacc agacacttcc
     2941 ggtatgatcg ttcatcagca cgccattaga aatacaatgg gcaacaaatt ttttactttc
     3001 tgctactgct ttggtaaaat ctgcccctaa cacaagattc gctgttattg cagaagaaaa
     3061 ggcacaaccg gccccgttta ctgttgtagt gtcgattttt ttatgagaaa atacctcata
     3121 atgatcaatt gaatagagaa gatccacagc ttcatctcca gccatccttg tgccgccttt
     3181 gatcacaatg ttttttgttc ctgaagcagt gagttcttta gcgagatgga tcatttctgt
     3241 taacgaagag ggaagagctt gaccagaaag taaagcagct tctgccaaat taggcgtaat
     3301 catcgtaaca agtggaaaaa gttcttcgat gagctgcgaa atatacaatt gattgatcac
     3361 agcttcagtt tctttgaatg ccaaaacagg gtctaaaatg attgggatat tttgttttgt
     3421 ttttatgaag tctcgaacaa ccatgattgc ttcacttgaa ttcaataacc caattttgat
     3481 accatctaat gaagtcattt tatcaatcga aactaactgt cgtttaagca attccaaaga
     3541 tatagattcc agcataaatc gctcattaat atctagtgcc cctatagaag tcaaggcgct
     3601 tagtccgaat agaccaaaat tctcaaaagt ttttaaatct gtttggattc ctccaccagc
     3661 aaatggatca gaaccgccaa ttgtcaagat tcttttcata acattttcct ccatgaataa
     3721 gagtataacg aaattttcaa aaaagaaaaa cagccaattg gcatattttt atctcatcca
     3781 atttaaaaaa acaaaaagaa aagaaagacc aaaatggatc tttctttcct taaatagtta
     3841 ggacttttgt gattttaatt ctttctcgat ttgaagccgt tgcactttca ttgtagctgt
     3901 tcgcgggatt gcatcaaaat cacggatgat agggacgttc aagcgaggaa gttcatggac
     3961 ttgctcccac catcgattcc aatccatttc tttatcagga gctaaagcaa taatcggttg
     4021 tggagaatga tttttatccc ttacaatcac tacttctgcc aaaaaatcta acgaatctaa
     4081 taaaaagtct tcaatagcta atgtactatt gatcgtttcg atcaaatcca cttgccgatc
     4141 tttcaaaaat aggtggccat gcttatccat aaaaccgtaa tctccgctat cccaccaatc
     4201 gccataaaca ttttcctgga accgtgcatc ttccttgtaa taagtcaaag cccgtccttt
     4261 agacagtaat tgtatatgac catctgtgtt ttcaggtagg acattcccaa ctgaatctgt
     4321 aatccgagcg cttgtcatgt cttccagtcc aacgcccata tctcttgcat cacttgtttt
     4381 caaactctct agtgtatgag ccttaagaat cattggtccg cattcacttt ggccatatac
     4441 ttgaagaaat accgcatcct gtgccatcga cgttcgcaaa aatgtcttca ttgtctggtt
     4501 gtttatagca tcaaaagtgg agtgatagta tcggataccc gaaaaagctt ctggatgctc
     4561 cttagcagta aaacgccact gaacaaagtt attcggatgg gtctctagtg caattggccg
     4621 gtgagcttcc aacatatgaa caacttttga actttgtgcg tttgctaaag gcatcatagg
     4681 aaatcccatg gacatcaaag aagagatacc aatattgaat ctggaatgca ctggagagat
     4741 gtgaaaagcg attaatttct tttccgaaat ttttgtgaaa actgtttttt gccatttcgt
     4801 ccgccatccc atagaatgag cagaatgaca aataagttta gggataccag ttgtaccaga
     4861 agtatgggtc atataagaaa tttcattttt gtctaaaaat gattgagaaa cagacaaagc
     4921 aggttgttcc attaaataaa gaatagg
//
LOCUS       DAZKCH010000129         4941 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000129 DAZKCH010000000
VERSION     DAZKCH010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.134"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..832)
                     /locus_tag="ACG84X_002670"
     CDS             complement(<1..832)
                     /locus_tag="ACG84X_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFP9128474.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(846..1643)
                     /locus_tag="ACG84X_002671"
     CDS             complement(846..1643)
                     /locus_tag="ACG84X_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFP9128475.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(1676..1960)
                     /locus_tag="ACG84X_002672"
     CDS             complement(1676..1960)
                     /locus_tag="ACG84X_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFP9128476.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTLSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(1957..2958)
                     /locus_tag="ACG84X_002673"
     CDS             complement(1957..2958)
                     /locus_tag="ACG84X_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFP9128477.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELFKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(2960..3862)
                     /gene="gnd"
                     /locus_tag="ACG84X_002674"
     CDS             complement(2960..3862)
                     /gene="gnd"
                     /locus_tag="ACG84X_002674"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFP9128478.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            4026..4874
                     /locus_tag="ACG84X_002675"
     CDS             4026..4874
                     /locus_tag="ACG84X_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9128479.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
BASE COUNT         1493 a         1080 c          799 g         1569 t
ORIGIN      
        1 aaaatccgtc atcatagtca tcttcgtcat caaaagatgc tgaattgtta ttgcttgtgg
       61 caggctgtac ttgtttccct ttttgcgact ggacaaagat caaagcgata ataatcccaa
      121 aaatggcata agtaaccatc gtaatatcta aagatttcaa aacaacactc ataaaataag
      181 caaggaagaa aaagaccaga taatcttttc gaccgataac gtatacagtt gtcgcgatac
      241 cgattgccgc taaccctcca cctactactt caagaatgtg gataacgact gttccctcta
      301 aagctttgat tacatcagcg atcaatggcg cccctaaata taaagcaatg aaaacaagcg
      361 gaacgaataa taaaaatgag gcaaccgttg gataaagaat aattgatcgg gccatagctt
      421 ttgtattcaa atcttctaca gctttgtctg tatatttacc taaaaaagta ttgatgaaaa
      481 aacgaaactg atacaagtaa cttccgagca atccgactgg caccgcaacg gcaatcgctg
      541 cttctggcga cagatcccct aataatgcga ctggtactgc gatagctgct gcaatagatg
      601 gttcagctgg cattgatcct cctggagaaa aaacccccat ataaatcatt tgcaaagcgg
      661 ctgtaacaat catcgcttgt gcaacttccc ccatgatcaa cccgacgact aatccagtca
      721 tcaaaggaga aaaacgtaag gtcaacgtgg ctcctccacc taaccagcgg gacataaccg
      781 cggctaccca taaagcaatc aacaaacttt gtactacact taatgtttcc atgtgtcctc
      841 ctccttcaga tctttctgat ataaccttcc agttccatca ttgactgtat cagtgatttc
      901 tgtgttacct ctataggaat caaatgcact ttctctttcg aatcaataaa ttcagccatt
      961 ttatctatta tctgtttatc tttcggaaat aatcccattt gttctagaga aaccggcagt
     1021 tctaattccc gatacaaagg atataactcg tctatttttt cccagcgacc ttctagtgcc
     1081 agttgataga aaatcccata cgctactttt tctccatgta gaaaacgatg gctttccgga
     1141 atatatttac tgatagcgtc atgcatagca tgtgctgcca catttcttgc gtatttatct
     1201 cctaatcctc caactaaacc agcaacagca aagataatct ctgaaagctg tttgaactcc
     1261 gatgtcagtt ttctttgtgc catatcttgg attgctttag cagaatgatt caaaatctct
     1321 tctttgcaga tcttcgcagt atcttgtgct agcttcaaaa atgattcatc ttgcaaaaaa
     1381 tcttgttcta agatgagctc agattcatac cattttgcta gtgtatctgc taacccggca
     1441 atgaaatatg gaacagggga atcaatcact aattggggat ctgttataaa aaaagcagct
     1501 tgtctgtaaa agtgttctgt tttcccttct gcttgtccat tctccttata catgacagca
     1561 agaggtgtcc atggagcaca attactagct aaagtaggga tgactccgaa atcgattctt
     1621 gcaagattgg cactataacc cactagatcg gtcagttttc ctccgccaac gccaactacg
     1681 aaatcgattt catttttttg atgattgtag ctattcgtct ggcttcagca taactacatt
     1741 ctccagaata acgatgataa aaaaattgaa tcgtttcgtc attcaaaaat actaatttag
     1801 gtagcgcctt ttcccatgat aacgttccgt gggtgaccag tactcttttc gcgccgtatg
     1861 atttcaagag atcagaaact tttgaaatac caccttcttc atataaataa aattgagggc
     1921 ctgttttcac ttttaaaccg ttcaccattt tcttcatcat ccttttatat agttgctctt
     1981 tgtctggaca gaacgttcag gaagaaggtg ctgactgatc tgttcgacat ctctgacaca
     2041 tttttcaccc attgcttcta aacattccct tgtgtaggcc gatatatgtg gcgtaatcac
     2101 tacttgttca aacgctaaat acggatgatc ttgacgtccc ggttcttctt ctaaaacatc
     2161 tgtggcatat cctgcgatct ttccgctttt cagaccatta atcatcgctt cttcatcaac
     2221 tagagcgcct cttgcactat tagatagata aacattttct ttcatctgat cgacttcttt
     2281 atcagaaatc atgtgatagt tctcttctgt caaattcgca cataaacaaa tgatatctga
     2341 ttgttccagt aattcttgaa gttctacttt ttttgcacca aagctttcga tgtataaatc
     2401 tgatttgtaa ggatcataag ctagaacatc acagcgaaaa ccgttacgca aaatttcgat
     2461 tactccgctt ccggtatttc ctgcaccaat cacaccaact gttttgttaa acagcgtcct
     2521 accgacgaac tccgcccgat cttcccatcg atcgtccttg actcttgctt gtgcttgtgt
     2581 cgtgcgtcga agcatggaca acaaattagt tatattattt tctgctacag catttcgttc
     2641 aactaaagca ggtatgatag atacgattgt ctggtgttct tttgctgctt ttaaatcaat
     2701 attgttgtaa ccaataccat gtcgggaaat caatagcagt tcatctttgt tttcaaaaaa
     2761 atctcgtcga aaaaatggcg taacacttgc aataatgata ttgaatcctt taaataactc
     2821 cgctagttct tttcctggaa tctcttgatc aacagtaaag aaatgaacgt ctccaactga
     2881 ctttaatctt tccaagtggt gtggaaagac tcttccgaaa ctgctggaat taacgattgc
     2941 tatatgataa tctggcattt tactcaccct tttcaactat ttcatgtccg ccaaacccat
     3001 ttcttagtgc tgaaactact tttgctgaaa aactatcttc ttcctgtgaa agattcctca
     3061 tgaacaaact agttgcaatt actggaactg gaacagccat ttctagcgct gtttcaaccg
     3121 tccattttgc ttcacctgat gcagaaacga ttccccgata attacttaaa ttgggatgtt
     3181 cgtttaactg atcttccatg atttccatca gccagccgcg aatcaccgaa ccatgattcc
     3241 aaacacgtgc gacttgttcc aagtcaaaag catactcact tttttgtaca agttggaatc
     3301 cttcaccgat tgcttgcatc attccatatt cgattccatt atggatcatt ttcaagaagt
     3361 gtccgcttcc ggatgcacca gcatacagat atcctctttc aattgctaca tctttgaata
     3421 attgttccac ggatagaaaa gtttctttat ctcctccaat cattaagcag gcttgatgtc
     3481 gtgctccttc gattcctcca gaagtcccac aatccaagta accgatttca tttttctgaa
     3541 actcttctgc tcgacggatt gaatctttat aataagagtt tccgccttca ataataatgt
     3601 ctcctggtcc gagttttgga aaaagttttc ttaacatgtt ttcggttatc tctccagcag
     3661 gaagcattaa ccagatgatt tttttctgct caaaagtagc tagaaattca gagatctctt
     3721 gataagcagg aatgtcattt tctcttgcct gactaacagc tgtacttgaa atgtcgagtc
     3781 cttgtacttt gtgatggtgc tcttttaagt ttaaagctaa attcaatccc atttttccca
     3841 aaccaattac accaatttcc atgatagcgc ctccatttct tataccctca ttatacaaaa
     3901 aaattttttt gtaaatagat tttacaaaaa tattttttgt ttgatttttt cctactctcc
     3961 ttgtatcttt aacattaatg agaacggaaa aaatgataat cttattatga aaatgaggaa
     4021 ttctcatgag cgtctccata agactacaaa tcaaaacaat gtacaacgac ttcagcccaa
     4081 aagaacaggc tatcgccgat tatattttag aaaatccaag caaagtaagt catagtccta
     4141 ttagcaattt agcaagtgaa ctgggcattg ctgactctac tttttttcaa tttacaaaaa
     4201 aacttggtta taatggattt aaagatttta aaatggccat gttgatccaa gaaaatgatc
     4261 tatctgctat ttctatccac gaaaatattc agaaaacaga tactgagctc actatggcgc
     4321 aaaaggtgtt cgagtctagt atttcaactt taaatgacac aaaaaagttg ttacaacaaa
     4381 aggatctaaa aaaagcggct actattatca atgaatctaa acgtgtctat tttttcggtg
     4441 ttggcggttc agagattgta gcaactgacg cttatcataa atttttgcgt tcccctatcg
     4501 caacttctca cagcacggat taccatattc aattgatgga agcttcttta ttgacggaaa
     4561 aagactgtgc tgttttgatt tctcacacag ggcaatcaaa agaaacaatc catattgctg
     4621 aaaccgtaag aaaaactgga gcaaaaacaa tcgttattac tagccaagct aattcttccc
     4681 ttgctaaact tggcgatgtc gtttttattt ctatttctga agaaacagaa ttccgatctg
     4741 aagctttagc ttcccgtatt tctcaactaa gcattttgga ctctctatat gtgattttga
     4801 tgttttacaa cgaaaaagaa tcacgtcgtt ctatcgctaa agttcgacat actatttctg
     4861 aaatcaaaga atagcaccat aacagaaaaa gcgaaaaatc cataaaacaa aaaaagccac
     4921 taccaaatat ttggtagtgg c
//
LOCUS       DAZKCH010000130         4892 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000130 DAZKCH010000000
VERSION     DAZKCH010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.135"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(287..649)
                     /locus_tag="ACG84X_002676"
     CDS             complement(287..649)
                     /locus_tag="ACG84X_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128480.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="ACG84X_002677"
     CDS             complement(723..1103)
                     /locus_tag="ACG84X_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFP9128481.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1185..2360
                     /locus_tag="ACG84X_002678"
     CDS             1185..2360
                     /locus_tag="ACG84X_002678"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFP9128482.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2437..3021)
                     /locus_tag="ACG84X_002679"
     CDS             complement(2437..3021)
                     /locus_tag="ACG84X_002679"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9128483.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3222..4220
                     /locus_tag="ACG84X_002680"
     CDS             3222..4220
                     /locus_tag="ACG84X_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFP9128484.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4332..4841
                     /locus_tag="ACG84X_002681"
     CDS             4332..4841
                     /locus_tag="ACG84X_002681"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFP9128485.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
BASE COUNT         1553 a          914 c          851 g         1574 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc ttactaggtt
     2401 tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt caattgtttc
     2461 aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg cgatttcatc
     2521 tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat ctagccaagg
     2581 agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac cttctagttg
     2641 tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc ttccgtttgt
     2701 gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt cacgactgaa
     2761 ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc cagttggatc
     2821 gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat cataataacc
     2881 ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag ggaataattg
     2941 aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt cactttttaa
     3001 atctagttgt gggaatgcca tattgtttcc tcctaatatt tgcatacttc ataataataa
     3061 taacataata cctaacctct cgtaaaaata ctagatttgt tttcttttat ttttcatcac
     3121 tagatacatt ctataactta ccgtttcgat ttcgaattca aacatttttg agaagcattc
     3181 tcaattaaat tctgctatag tgtgaaaagg gaggaatttt tatggaaatc tatgacatta
     3241 caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt ttacgcagga atgcgccaag
     3301 ctaaaacaaa aatcattgac agtctacctc aacttggtgg tcaattagca actttgtatc
     3361 ccgaaaaata tatttacgat attcctgggt atccagcaat aaaagcaagt gaattaatcg
     3421 atcaattaga aaaacaatta actactttta accatacatt ccatttaaaa gaagaagttc
     3481 tctcgcttac tcgtgaagac gaagttatcg agattactac aaataaaggc atccattatt
     3541 ccaaagcagt cattttagct ttaggaaatg gttcattcca gccaagaaaa ttgaatttag
     3601 ataatgctga atcatttgaa aaccacggat tggattattt cgtgaatgat ttgatgaagt
     3661 atgctggaaa aaaagtcgct attgctggag gtggtgattc tgctatcgat tggacgttga
     3721 tgttagagcc tattgcaagc gaagtttact tgattcatcg tcgcccggaa tttcgtgcgc
     3781 acgaacatag tgtatcacgc ttgaaatctt catctgtcaa cttgcttact ccctatctca
     3841 tcgatggatt atcaggcaat aatggggaac tgacagatat ccggttaaaa aaagtgaaaa
     3901 gtgacgagac gattgatttg atgattgatt ctctgatcgt caattatgga ttctcttcta
     3961 atttagaaca tctttcttct tggggacttg atagtaccag aaatgccatt actgtaaaat
     4021 cagatatgtc tacttctatt ccaggcgttt atgcagctgg tgacatctgt acctatgaag
     4081 gaaaagtgaa actgattgct actgggctcg gtgaagcacc tactgcagtg aacaacgctt
     4141 tacactatat taatccaaag gaacgaactc agcctggtca cagcacaagc ttatacgata
     4201 aaaatcttcg tcctagttga ttttttatat ctctttgcat ttcaagttaa acccgaaagc
     4261 agtttcttgc atttttttca tgttccgtta acatgaaata gagaaagaaa aaataaaggg
     4321 ggagcaataa tatggtcgtc aaaactgaga ctttagaaga aaaggcaaga gaactattga
     4381 aggaacgtgg cgtaactgta gaagatatcg cacaacttgt catgttttta caaaaagact
     4441 atatttctga tttgactttg gcggattgta ctgaaagtgt caacagcgtg ctaacaaagc
     4501 gtgaagtaca taacgccatt atcactggaa tccaattaga tatattagca gaaaagaaaa
     4561 aattgatgag tccgttgcaa catattatcg aagatgacga aggcctttac ggtatcgatg
     4621 agatcctagc cttgtcaatc gtgaatgttt acggtacgat cggctttacg aattatggtt
     4681 atatcgacaa ggtgaaacct ggtattttaa aagaactaaa cagccacgat ggcgttcatg
     4741 tccatacctt cttagatgat atcgtcggag cgatcgccgc tgctgctgcc agtcgattag
     4801 cacacaaaga accagaaaaa agaagtcgcc ttactcaata attcaacaaa aaaagaaaga
     4861 aaacgtctat ttagacgagt tctttctttt tt
//
LOCUS       DAZKCH010000131         4757 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000131 DAZKCH010000000
VERSION     DAZKCH010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4757
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.137"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            51..746
                     /gene="vanR-A"
                     /locus_tag="ACG84X_002682"
     CDS             51..746
                     /gene="vanR-A"
                     /locus_tag="ACG84X_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFP9128486.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            724..1878
                     /locus_tag="ACG84X_002683"
     CDS             724..1878
                     /locus_tag="ACG84X_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFP9128487.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2093..3061
                     /locus_tag="ACG84X_002684"
     CDS             2093..3061
                     /locus_tag="ACG84X_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFP9128488.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3054..4085
                     /gene="vanA"
                     /locus_tag="ACG84X_002685"
     CDS             3054..4085
                     /gene="vanA"
                     /locus_tag="ACG84X_002685"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFP9128489.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4091..4699
                     /locus_tag="ACG84X_002686"
     CDS             4091..4699
                     /locus_tag="ACG84X_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFP9128490.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1471 a          910 c         1115 g         1261 t
ORIGIN      
        1 tataatctga taaattatta agggcaaact tatgtgaaag ggtgataact atgagcgata
       61 aaatacttat tgtggatgat gaacatgaaa ttgccgattt ggttgaatta tacttaaaaa
      121 acgagaatta tacggttttc aaatactata ccgccaaaga agcattggaa tgtatagaca
      181 agtctgagat tgaccttgcc atattggaca tcatgcttcc cggcacaagc ggccttacta
      241 tctgtcaaaa aataagggac aagcacacct atccgattat catgctgacc gggaaagata
      301 cagaggtaga taaaattaca gggttaacaa tcggcgcgga tgattatata acgaagccct
      361 ttcgcccact ggagttaatt gctcgggtaa aggcccagtt gcgccgatac aaaaaattca
      421 gtggagtaaa ggagcagaac gaaaatgtta tcgtccactc cggccttgtc attaatgtta
      481 acacccatga gtgttatctg aacgagaagc agttatccct tactcccacc gagttttcaa
      541 tactgcgaat cctctgtgaa aacaagggga atgtggttag ctccgagctg ctatttcatg
      601 agatatgggg cgacgaatat ttcagcaaga gcaacaacac catcaccgtg catatccggc
      661 atttgcgcga aaaaatgaac gacaccattg ataatccgaa atatataaaa acggtatggg
      721 gggttggtta taaaattgaa aaataaaaaa aacgactatt ccaaactaga acgaaaactt
      781 tacatgtata tcgttgcaat tgttgtggta gcaattgtat tcgtgttgta tattcgttca
      841 atgatccgag ggaaacttgg ggattggatc ttaagtattt tggaaaacaa atatgactta
      901 aatcacctgg acgcgatgaa attatatcaa tattccatac ggaacaatat agatatcttt
      961 atttatgtgg cgattgtcat tagtattctt attctatgtc gcgtcatgct ttcaaaattc
     1021 gcaaaatact ttgacgagat aaataccggc attgatgtac ttattcagaa cgaagataaa
     1081 caaattgagc tttctgcgga aatggatgtt atggaacaaa agctcaacac attaaaacgg
     1141 actctggaaa agcgagagca ggatgcaaag ctggccgaac aaagaaaaaa tgacgttgtt
     1201 atgtacttgg cgcacgatat taaaacgccc cttacatcca ttatcggtta tttgagcctg
     1261 cttgacgagg ctccagacat gccggtagat caaaaggcaa agtatgtgca tatcacgttg
     1321 gacaaagcgt atcgactcga acagctaatc gacgagtttt ttgagattac acggtataac
     1381 ctacaaacga taacgctaac aaaaacgcac atagacctat actatatgct ggtgcagatg
     1441 accgatgaat tttatcctca gctttccgca catggaaaac aggcggttat tcacgccccc
     1501 gaggatctga ccgtgtccgg cgaccctgat aaactcgcga gagtctttaa caacattttg
     1561 aaaaacgccg ctgcatacag tgaggataac agcatcattg acattaccgc gggcctctcc
     1621 ggggatgtgg tgtcaatcga attcaagaac actggaagca tcccaaaaga taagctagct
     1681 gccatatttg aaaagttcta taggctggac aatgctcgtt cttccgatac gggtggcgcg
     1741 ggacttggat tggcgattgc aaaagaaatt attgttcagc atggagggca gatttacgcg
     1801 gaaagcaatg ataactatac gacgtttagg gtagagcttc cagcgatgcc agacttggtt
     1861 gataaaagga ggtcctaaga gatgtatata attttttagg aaaatctcaa ggttatcttt
     1921 actttttctt aggaaattaa caatttaata ttaagaaacg gctcgttctt acacggtaga
     1981 cttaataccg taagaacgag ccgttttcgt tcttcagaga aagatttgac aagattacca
     2041 ttggcatccc cgttttattt ggtgcctttc acagaaaggg ttggtcttaa ttatgaataa
     2101 catcggcatt actgtttatg gatgtgagca ggatgaggca gatgcattcc atgctctttc
     2161 gcctcgcttt ggcgttatgg caacgataat taacgccaac gtgtcggaat ccaacgccaa
     2221 atccgcgcct ttcaatcaat gtatcagtgt gggacataaa tcagagattt ccgcctctat
     2281 tcttcttgcg ctgaagagag ccggtgtgaa atatatttct acccgaagca tcggctgcaa
     2341 tcatatagat acaactgctg ctaagagaat gggcatcact gtcgacaatg tggcgtactc
     2401 gccggatagc gttgccgatt atactatgat gctaattctt atggcagtac gcaacgtaaa
     2461 atcgattgtg cgctctgtgg aaaaacatga tttcaggttg gacagcgacc gtggcaaggt
     2521 actcagcgac atgacagttg gtgtggtggg aacgggccag ataggcaaag cggttattga
     2581 gcggctgcga ggatttggat gtaaagtgtt ggcttatagt cgcagccgaa gtatagaggt
     2641 aaactatgta ccgtttgatg agttgctgca aaatagcgat atcgttacgc ttcatgtgcc
     2701 gctcaatacg gatacgcact atattatcag ccacgaacaa atacagagaa tgaagcaagg
     2761 agcatttctt atcaatactg ggcgcggtcc acttgtagat acctatgagt tggttaaagc
     2821 attagaaaac gggaaactgg gcggtgccgc attggatgta ttggaaggag aggaagagtt
     2881 tttctactct gattgcaccc aaaaaccaat tgataatcaa tttttactta aacttcaaag
     2941 aatgcctaac gtgataatca caccgcatac ggcctattat accgagcaag cgttgcgtga
     3001 taccgttgaa aaaaccatta aaaactgttt ggattttgaa aggagacagg agcatgaata
     3061 gaataaaagt tgcaatactg tttgggggtt gctcagagga gcatgacgta tcggtaaaat
     3121 ctgcaataga gatagccgct aacattaata aagaaaaata cgagccgtta tacattggaa
     3181 ttacgaaatc tggtgtatgg aaaatgtgcg aaaaaccttg cgcggaatgg gaaaacgaca
     3241 attgctattc agctgtactc tcgccggata aaaaaatgca cggattactt gttaaaaaga
     3301 accatgaata tgaaatcaac catgttgatg tagcattttc agctttgcat ggcaagtcag
     3361 gtgaagatgg atccatacaa ggtctgtttg aattgtccgg tatccctttt gtaggctgcg
     3421 atattcaaag ctcagcaatt tgtatggaca aatcgttgac atacatcgtt gcgaaaaatg
     3481 ctgggatagc tactcccgcc ttttgggtta ttaataaaga tgataggccg gtggcagcta
     3541 cgtttaccta tcctgttttt gttaagccgg cgcgttcagg ctcatccttc ggtgtgaaaa
     3601 aagtcaatag cgcggacgaa ttggactacg caattgaatc ggcaagacaa tatgacagca
     3661 aaatcttaat tgagcaggct gtttcgggct gtgaggtcgg ttgtgcggta ttgggaaaca
     3721 gtgccgcgtt agttgttggc gaggtggacc aaatcaggct gcagtacgga atctttcgta
     3781 ttcatcagga agtcgagccg gaaaaaggct ctgaaaacgc agttataacc gttcccgcag
     3841 acctttcagc agaggagcga ggacggatac aggaaacggc aaaaaaaata tataaagcgc
     3901 tcggctgtag aggtctagcc cgtgtggata tgtttttaca agataacggc cgcattgtac
     3961 tgaacgaagt caatactctg cccggtttca cgtcatacag tcgttatccc cgtatgatgg
     4021 ccgctgcagg tattgcactt cccgaactga ttgaccgctt gatcgtatta gcgttaaagg
     4081 ggtgataagc atggaaatag gatttacttt tttagatgaa atagtacacg gtgttcgttg
     4141 ggacgctaaa tatgccactt gggataattt caccggaaaa ccggttgacg gttatgaagt
     4201 aaatcgcatt gtagggacat acgagttggc tgaatcgctt ttgaaggcaa aagaactggc
     4261 tgctacccaa gggtacggat tgcttctatg ggacggttac cgtcctaagc gtgctgtaaa
     4321 ctgttttatg caatgggctg cacagccgga aaataacctg acaaaggaaa gttattatcc
     4381 caatattgac cgaactgaga tgatttcaaa aggatacgtg gcttcaaaat caagccatag
     4441 ccgcggcagt gccattgatc ttacgcttta tcgattagac acgggtgagc ttgtaccaat
     4501 ggggagccga tttgatttta tggatgaacg ctctcatcat gcggcaaatg gaatatcatg
     4561 caatgaagcg caaaatcgca gacgtttgcg ctccatcatg gaaaacagtg ggtttgaagc
     4621 atatagcctc gaatggtggc actatgtatt aagagacgaa ccatacccca atagctattt
     4681 tgatttcccc gttaaataaa cttttaaccg ttgcacggac aaacggttct gttgcaaagt
     4741 tttaaataaa gaataaa
//
LOCUS       DAZKCH010000132         4664 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000132 DAZKCH010000000
VERSION     DAZKCH010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.138"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(104..1336)
                     /locus_tag="ACG84X_002687"
     CDS             complement(104..1336)
                     /locus_tag="ACG84X_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFP9128491.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1591..2160
                     /locus_tag="ACG84X_002688"
     CDS             1591..2160
                     /locus_tag="ACG84X_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9128492.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2338..2778)
                     /locus_tag="ACG84X_002689"
     CDS             complement(2338..2778)
                     /locus_tag="ACG84X_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFP9128493.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2936..3700
                     /gene="map"
                     /locus_tag="ACG84X_002690"
     CDS             2936..3700
                     /gene="map"
                     /locus_tag="ACG84X_002690"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFP9128494.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3732..4655
                     /locus_tag="ACG84X_002691"
     CDS             3732..4655
                     /locus_tag="ACG84X_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFP9128495.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
BASE COUNT         1412 a          865 c          925 g         1462 t
ORIGIN      
        1 aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt agatccttta
       61 ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc caatcgccat
      121 ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc atcttgtcag
      181 atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct gctaattctt
      241 catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct agtgctaagt
      301 gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat tgagaaatag
      361 gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca tctgtatcaa
      421 gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaacaact tttccatctt
      481 taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc tttgtacttg
      541 aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc gtcggcatat
      601 ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa agatggtttt
      661 taggcaatcc gataatgata tctgtaccgg gagcagtata gtgaagggca gaaaattgtt
      721 ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc catgctaaga
      781 cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat gcctcaactt
      841 gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca gccgcagcca
      901 cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt agtgctttgc
      961 cattcgctga ttgataagac gctactcgat ggctatctac accagcaaat gcatcgggat
     1021 cggcagaaac aacgctgatc ctgcttgctc ctttttcaag ccattcatcc gcttgatcga
     1081 ttttagattg tggtacattc tcaatacgat ccgttgcagc atgtaaaaga aattctcttt
     1141 ggatctggtc gtcagtccat tgaacgataa cctcagcggc tcctagttta taagcttctt
     1201 gtgtgatcaa tcgagcaagg ggtgcctgtt ccacgctgat ctgtaaaaca actgtgtgtc
     1261 ctttttctgt ggctacgcca gtttctgcaa ttaagcgtgc atattttttt agaagttcat
     1321 taaaatcaga taacataata aaaattcctc ctcaccattt tttctggtaa ctattagcat
     1381 gataccattt aattatgatt caaacaatga ggctttaaat aaaaaaagga ggttattttt
     1441 ttaaggttaa gtttcatgat atatgttact acttgctatt tcagcttgtg aagaaaatca
     1501 aaaactaatt ttgcatatca aaaaaaacat gttacaatga aattaatcaa tggtggaagc
     1561 gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat tactagagaa
     1621 cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg atttactgcg
     1681 agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga gtttaaaaat
     1741 atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca atatgaagtg
     1801 ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta tatccatttt
     1861 gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg tggaggaaaa
     1921 gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga tccagcttat
     1981 gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat catagctact
     2041 gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca gattgaaaag
     2101 atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga aatcgattga
     2161 atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa taaggaaaag
     2221 ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca tgaatgcaat
     2281 gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc aagtatatta
     2341 aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt cttcttcagc
     2401 attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg caaaagcagc
     2461 atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag atccgcagac
     2521 accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt ctacgatctc
     2581 atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat ctgcctcctc
     2641 gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat ccagattttc
     2701 aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc tagcatatac
     2761 gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa ttatgaatta
     2821 taccaaaaca tcattgaaaa gaaaataaaa cctagagaca cctggggaat gtcatttggc
     2881 taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg aaaatatgat
     2941 tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt tattagcaga
     3001 tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg atattgaggt
     3061 atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg gctttgaagg
     3121 gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat tccctcgtaa
     3181 aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt tgaaaggcgg
     3241 catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga tcgaccgatt
     3301 gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag tagggaatcg
     3361 gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc tagcgatcgt
     3421 tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag cagttcctca
     3481 ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca cgatcgaacc
     3541 tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga ctgcgtatac
     3601 aagagacggc ggactttctt gccaatatga acatacattg gctattacta aagatggtcc
     3661 aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt caataggtac
     3721 gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg atgcgcttta
     3781 ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct gtcgtcgttg
     3841 cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat attttaccgt
     3901 ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt cctgagaccg
     3961 tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca ggaggcttgt
     4021 tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat gctttgcaaa
     4081 ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc gtccgtttct
     4141 tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact atcgttcttg
     4201 ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc gtgaacttta
     4261 tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt gtcatcatgt
     4321 tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc attccgggca
     4381 cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc tatgctaggt
     4441 attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta ctcatgcttt
     4501 ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca gttgttcaag
     4561 aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa tggttcaata
     4621 aattgaaaac taaattttct cataaaaaaa agtagaaaca agag
//
LOCUS       DAZKCH010000133         4525 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000133 DAZKCH010000000
VERSION     DAZKCH010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.139"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(44..418)
                     /locus_tag="ACG84X_002692"
     CDS             complement(44..418)
                     /locus_tag="ACG84X_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9128496.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
     gene            complement(441..1841)
                     /locus_tag="ACG84X_002693"
     CDS             complement(441..1841)
                     /locus_tag="ACG84X_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HFP9128497.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            complement(1845..2255)
                     /locus_tag="ACG84X_002694"
     CDS             complement(1845..2255)
                     /locus_tag="ACG84X_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9128498.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            complement(2273..2764)
                     /locus_tag="ACG84X_002695"
     CDS             complement(2273..2764)
                     /locus_tag="ACG84X_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFP9128499.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            complement(2774..3565)
                     /locus_tag="ACG84X_002696"
     CDS             complement(2774..3565)
                     /locus_tag="ACG84X_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9128500.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            complement(3558..4331)
                     /locus_tag="ACG84X_002697"
     CDS             complement(3558..4331)
                     /locus_tag="ACG84X_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFP9128501.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
BASE COUNT         1405 a          943 c          597 g         1580 t
ORIGIN      
        1 agtacttttc gttcatacca acttagagca cttcgttatc tatttatttc ttcatttggc
       61 ttatctctat aatctcatga tttggtccgt agaaattaaa gtaacggatt ccattttccc
      121 agaacggtaa ttccataata tttttatcta ataattcata tcctaaatct tgaattgaat
      181 tgaatacctc atctatgtca tccgtatcta atgctagatg atcaatggct cctctacact
      241 cagtagtttt atcttcccat atttctatta tcgttccatt caactcgaaa aagccgactt
      301 tacttcccac attcatttct tcattaatca gactaaaccc taaggattca taaaagattt
      361 ttgaagctcc aaaatctttt gttggaattc caatatgttg taaaccattt aatttcactt
      421 acatcatccc ttcaattgtt ttaaaatcca cattcataat ttattgaata gtctagttta
      481 tctaccttga ttgctccctc cgtaacagtc atacttaatg ctgttccgac tttatcatac
      541 attctagtac ttaaagcaac attatcaata tataaaacag ctatcgtatc atcaacaatt
      601 aactttagtt catattcttt gcctatttcc aaaaatagtg gtcgttgcag ccccttatca
      661 aacatttgag gccaaggata gttcggagtt tttccgaaag taagctgatt attaatcaat
      721 gaaatacgaa attcgtatcc ttcttgagta tcactatcta caaataattt taaagcaaac
      781 tcctttgtta acgatgtaat agtcaaagtt gtttcaaata gaaaataatc ttcgatttta
      841 ggaacaatta ctctttcttt ttttccaaat tctttctcta acttaaaact tgaaaatgga
      901 gtgatttctt taaaattctc aattattttt tcaggcagtt taacaccaag agttttgtct
      961 gtcttttgaa taatttgatg tggaacaagt gcaccgcccc aatcccagtt attttgatcg
     1021 ttctcccctt cttttgttgc cacccagcca gttagaaaac ggccagtttc attagttccg
     1081 actgttcttg ctgcataata ggcttttccg tcgaaagctt cgtctactgg tgatttccaa
     1141 tctgaaaata atcctgctcc gactcgatat ttagtctttt tatcttcaca atactctgaa
     1201 aaaagtaaat accacgttcc atcaatttca aatatatcag gcatttcaat catgttaaat
     1261 tcattattag cccagtagtc tcctttgaaa ttccaatctt ttaaatcttc ggattcaaaa
     1321 tagaccaatc tccccgtcgg ctttttctta cttgctggtt ttctagctcc tagtatcaaa
     1381 acgtattttc catgatcttg atcaaaaatt gcaaaaggat cgcgccaatc attcttatca
     1441 tatccttctt gaggaacaag ttttgctgct tcgccatcct ttttccaatg aattaaatct
     1501 ttagaacttg caatcattaa cacttctgaa gtttttccat ccaacttagc tttgcgatta
     1561 tgtccagtat acaaagctaa atactcattg attccttgga caatacttcc agcgtaaatg
     1621 tattgatcaa tgtcatcgtt gccaccacga tgaattactt ccccgtattc ttcaaatttc
     1681 acaaaatcag tggttgtaac tagtgaccac ccaaaaggat cagttaaagg tttaggattt
     1741 ctcgtatctc gttgatgaaa tagataaaaa gttccatctt tataaaaagg catgcaatcc
     1801 ccaaaccaaa aatctttagg cttgtaaaaa attttttgca tttatcactc atcctcttcg
     1861 ttagtatgtc tttgcatatc tgcaagacac gcaattgtat tcatatttct tagattttcg
     1921 atgatatcat cgcttttttt tccttgtaat ctcaaattga cagcctcaat caaaattcct
     1981 aaattcatgc caccaagaag ttgaaaccca ttttgaaata cttcacttct tttagcaaat
     2041 tcgttgaaag gtgttccacc aatcaagtca gcaaatacca taacttcttg attttttact
     2101 tgagaaacta ttttttcaat gttttcacgg aattcttcaa tgcctgcatc tccaagtgtt
     2161 accacatgac aatttaaatt atcgccaaaa aacattttta atgtatctac aaatccaatg
     2221 gcaatatttc catgagatgt aattataaac tccatccact catcctctgt tcttaataaa
     2281 taaaatcctt taaaaattct tttgaatctc taggagtttg tatcactgtc acttcaactc
     2341 catcactaat tagttcttta aaagcctctc tctcttcttc agtaatattt atcgtcggac
     2401 ggatgcgttc tgttccattc cttcttgata aatttcctac gtttacactt gttattggta
     2461 aaccgttatc aatcaaaaat ttaacatcga ttggagaaac tgcaacaata agaacttttt
     2521 gtccttcata tttaccagaa agaatatttt taactgctac ttcccttgta attattgaag
     2581 ttctaacatt aggtggtgca gcgaggcgaa ctacagcttt ttttacgtca tcattggcta
     2641 cttcattatt aataaccata attctgttag cactcaattg atttgtccat tgtgttgcta
     2701 cttgtccatg aatcattcga tcatcaatac gaacatgtat aatacctttc attttttcat
     2761 ccatattcaa cacctacttc aaaatattta acgctcttaa cgcaatagaa actactaaga
     2821 ttaatagaat tacataaact ggtttaacct ttcgtcctaa caaataatac acaattgcta
     2881 ctacacatgc aggtaataaa ccaggcataa cttgatcaaa gatttcattt ccggtcattg
     2941 ttaagtcgcc ttgtttaaat tcaaagccaa cattcacttt tacaactgtg gcaatgagtg
     3001 caccgaccac cattaaccct aaaattgata ctgcatcagt aatagacttt aattttgttt
     3061 caatttgagt tagtaggctc gcacccgatt ctttcccagc aaggtataaa ggataagcag
     3121 taatccttaa taaaattgat gccagtatcc acaaaataat tccaacaaaa ctaccttcca
     3181 atgccatatt agctgcaatt gctccaaaaa tagtccatgg aataactaca aatacactat
     3241 ctccaattcc cgctaaagga cccattagac ctgttttcag agcacttact gcttccaaag
     3301 acttattttt ttcttctttt tcaattccaa cattcatacc aataatgtaa ggcgctgtat
     3361 acggcgtagt gttaaaaaat tgtaggtgag ctaaaacgga ttgtttcatt ccttcaggat
     3421 catctttata tgtgtccttg ataaaaggaa gcatagaata cgcataaccc aacccttcca
     3481 ttttttcata atttaatgaa gttgcaccat tgagaatcca ccggaaaatt acttgtttgt
     3541 cgatttttgt cagtttctta ttcatcttcg tcaaaacctc ctgttgcagc tggtgctact
     3601 tgagtattat ttgatctatt tttatatacg attagtgcga ttgcagcgcc aagtaacgaa
     3661 atccctaaaa ttggtatttg gaaataaact gccaaaacga aaccaactaa caaataggca
     3721 aagtaatctt ttgtaggtaa atatttaagt agcattccta tcccaacagc aggtaatagt
     3781 ccccctgcta cctttaaacc accggtaacc cattcaggaa tataattgat tgcacttccc
     3841 actaacgttg ggcctaatat cacagttaac aaaacaggaa ttccagatac aaagcttgta
     3901 ttaattgatg ccaaatattg catccactct aatttttgat aatcttcttt ttgtgcgaat
     3961 ttttctgcct tttgttgaaa aaaaatgttt gttgaccact ttagaacatc tagttgtaca
     4021 attaacattg ctaccggtat tgctaaagtt attcctatag aagcatcctg gttagttgag
     4081 attgctaaat aagtaccgat caatgctgct gtttgataat ccggtactga tgcaccacca
     4141 aaactagtaa tacctagtgt cattaattgc aaagtcccac cgatataaag tccagtttga
     4201 atatctccca taataagtcc ggtcaagaaa cctgcaacga caggttggga ggttccgatt
     4261 ttgggccctt ccttatccca gttaatgaaa aatccataca acacaactaa aaatgtttgc
     4321 caaaacgcca ttttgttctc tcctttcttc ttatactttt atataagcaa ttactgtgcc
     4381 aactaacatt atccaataaa gcgggaaaat acagtaaata ttaattaaat gagcgtctaa
     4441 atatactttg gacacccttt cattttttta gacgctagta tgctatttag aaaatagtct
     4501 gctcaaaaat tgtatagatt aactc
//
LOCUS       DAZKCH010000134         4434 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000134 DAZKCH010000000
VERSION     DAZKCH010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.140"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(543..2048)
                     /locus_tag="ACG84X_002698"
     CDS             complement(543..2048)
                     /locus_tag="ACG84X_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9128502.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDN
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="ACG84X_002699"
     CDS             complement(2045..2731)
                     /locus_tag="ACG84X_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9128503.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACG84X_002700"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACG84X_002700"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFP9128504.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1240 a          919 c          729 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgcat tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat attt
//
LOCUS       DAZKCH010000135         4377 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000135 DAZKCH010000000
VERSION     DAZKCH010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.141"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            73..234
                     /locus_tag="ACG84X_002701"
     CDS             73..234
                     /locus_tag="ACG84X_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFP9128505.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..1530
                     /locus_tag="ACG84X_002702"
     CDS             253..1530
                     /locus_tag="ACG84X_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9128506.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="ACG84X_002703"
     CDS             1540..2196
                     /locus_tag="ACG84X_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128507.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="ACG84X_002704"
     CDS             2196..3572
                     /locus_tag="ACG84X_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9128508.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3702..4115
                     /locus_tag="ACG84X_002705"
     CDS             3702..4115
                     /locus_tag="ACG84X_002705"
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9128509.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIADCRQKLFQTRNSSLEQLFIYFVSNF"
     gene            complement(4140..4377)
                     /locus_tag="ACG84X_002706"
                     /pseudo
     CDS             complement(4140..4377)
                     /locus_tag="ACG84X_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611630.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1699 a          522 c          761 g         1395 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catcgcagac tgtagacaaa agctgttcca aactcgtaac tcgagcttgg
     4081 aacagctttt tatctacttc gtttcgaatt tttgaacaaa aaaataaagg ctccttgcct
     4141 ttccatagcc aggtggctaa tttctttaaa ttcattgcag caaacactag catcgtatgc
     4201 gtcgcgactt tttccaagcc tcgatacttg gtccaacgca tcccatgctt ttcttttgca
     4261 tccgcaaata ttcgttcaat cgtttgtttc cgttttttgt aaattgattt attcagatct
     4321 gttaggcgaa gatgttccac ttcatccatc agatctcccc aaacatgtct cgtgatg
//
LOCUS       DAZKCH010000136         4293 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000136 DAZKCH010000000
VERSION     DAZKCH010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.142"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..788
                     /locus_tag="ACG84X_002707"
     CDS             <1..788
                     /locus_tag="ACG84X_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFP9128510.1"
                     /translation="GYSKTEPRHSFGPAIREQYLIHIVLEGEGYYSINDQKYFLKKGQ
                     GFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYYLKEIGVGKNHLTFKVENLNSFKG
                     LIFETLSYDQDNLVSELSRQKQVYKFLELLLNSASYLNEGIITKKMNPFVRQTIEIIR
                     ENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISIKEYISEIKISIANDLLSSTEYSI
                     QQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRLGLGIINGE"
     gene            885..3134
                     /locus_tag="ACG84X_002708"
     CDS             885..3134
                     /locus_tag="ACG84X_002708"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFP9128511.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3137..>4293
                     /locus_tag="ACG84X_002709"
     CDS             3137..>4293
                     /locus_tag="ACG84X_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9128512.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRV"
BASE COUNT         1501 a          610 c          791 g         1391 t
ORIGIN      
        1 gtgggtattc aaaaacagaa cctagacata gttttggacc agctattcga gaacaatact
       61 taatacacat agtgctagaa ggtgaaggct attattcaat taatgatcaa aaatattttc
      121 tgaagaaagg ccaaggattt gttatcccac caggagtatc tactttttat caagcagatg
      181 aaaaaaatcc gtggtcatat gtatggttgg gtttaagtgg caatcttgta gaatactatc
      241 taaaagaaat tggtgttgga aagaatcatc ttacctttaa agtcgaaaat ttaaattcat
      301 ttaaaggatt aatttttgaa actttatcgt atgatcagga caatctagtc agtgaattgt
      361 ccagacaaaa acaagtttat aaatttttag aactcctctt aaattcagct agttatctga
      421 acgaagggat aattactaaa aagatgaatc cttttgttcg tcaaacaatt gaaataatac
      481 gtgagaatgc gtatcaaaaa ttatctgtta aagatattgc tgtcagtcta tcgatacacg
      541 aaaattattt atcacgattg tttaagaatg atatgggaat atcaataaaa gagtatatta
      601 gtgaaatcaa aatttctatt gcaaacgatc tgttatcatc aactgaatat tcaatccagc
      661 aaatcagtga caagatagga ttctcaacag tacaatcttt ttctaaagcc tttaagaaag
      721 caaatggtgt ttcaccggga gtatatcgaa aacgtagatt aggtctagga atcattaatg
      781 gtgaataaac taaacatttg attttgataa atattcgtta ctttaaacgc ttactattta
      841 tgtgagcgtt ttttataatg caataaagaa acggaggaga gcttatgtat aaggataatg
      901 aaatgaatat tatttatcga tcagaaaacc aacaatttca tttgtttaat caggagataa
      961 gttacatttt taagatatcg gaagatggta aattattgca tttatattat ggtgagaact
     1021 taccagataa tgactatagt catctaattg agatgcatca tcggcctatg acaacctata
     1081 gaaatgaaaa cgatttgcta tattcgttag agcacttaaa acaagaattt cctgaatatg
     1141 gtacaacaga ttttagacat cctgctattt cattactaca gaaaaatggc tctcgcttat
     1201 cagattttgt ctatcaaggg tacgaagtgg aagaaggaaa acctaaacta gaaggtttac
     1261 ctgctaccta tgttgataat aatgatgaaa gcaaaacatt gaaagtttat attttagatt
     1321 cagttacaaa tgttcaagta gaattattat atacaattta tagagattat cctgttatta
     1381 ctcgtagcgc gcgagttatg aataaaggaa aagatattca aataatcgag aatattagca
     1441 gtttatcatt ggatttaccc gatgcaaatt atgaatggca acaattatct ggtgcttggg
     1501 gtagagaaag aactattaag tcgcgtactt tacaacaagg aattcaatca atcgaatcta
     1561 ctcgaggtat ttcaagccat cagcataacc catttgttac tttaaaaaga aaaaatactg
     1621 atgaaaatca aggagaagct attggtgcag cactagttta ctcaggaaac ttcttaattc
     1681 aagcagaagt agatacatgg gatgttacta gactacaagt tggcatcaat ccatttggat
     1741 ttaattggaa actcaatcca ggagaaatat ttacagcacc agaagcgatt ctggtttatt
     1801 caagtaaggg tttaaatgcc atgagtcaaa cttttcatca actatttaga aaacgcttag
     1861 ctcgtggtaa gtggcgagaa aaagaccgtc ctgtcttaat taataattgg gaagcaacat
     1921 attttgattt tgacgaagaa aagttggtaa atattgctaa aaaagcattt gatgttggta
     1981 ttgaattatt tgtattagat gatggctggt ttggagaaag agaaaacgat tgtgcaggat
     2041 taggagattg gcatgtaaat cctaaaagac tacctagagg aatcggcagc ctttcagaaa
     2101 aaattcgtag ttttggtatg aaatttggtt tatggtttga acctgaaatg gtgaataagg
     2161 atagtgagtt atatcgcaca catccgaatt ggattatttc tacacctaat cgaaaaccta
     2221 atcatggtag gaaccaatat gtattaaatt ttgggttaga tgaggttgtt gaaaatattt
     2281 tcgatcaaat gtgtaaaatc attgatgaat caaacttaga ttacattaag tgggatatga
     2341 atcgtccatt gactgatgta tttgacagtc acttgtcagc agatcaacaa ggagaagtat
     2401 tccacagata tgtactaggc gtatatcgct tatatgaaaa acttataaca aaatatccta
     2461 acatactatt tgagtcttgt tcatcaggtg gtgggcgctt tgatcctgga atgcttcact
     2521 atgcacctca agcttgggct agtgatgatt cagatgcaat tgaaaggtta aaaattcaat
     2581 atggaactag tatgctgtat cctctttcgt ctattggtgc tcatgtatca attgttccaa
     2641 atcatcaaac aaaccgtata acacctataa aaactagagg aaatgtagct ttttttggtg
     2701 catttggata tgagcttgac ttaaatgaat taagtgaagg cgatttgagg attgtaaaag
     2761 aacaaattgc cttttataaa aaatatagaa ccataattca taatggtact ttttatagac
     2821 tattatcacc attcgatgat gataatcaaa ccgcgtggat ggttgttagt catgataaga
     2881 aaacggctat tgttgctcat tataaaacat taaatgaggt aaatgctcct taccgccgac
     2941 tgaaattaaa agggttagat aatgacggac tttataatgt aggacaaaat agtttgcgat
     3001 ctggaatgga attgatgaga gcaggactag tctgttcaga tgcatctagt ggacaaataa
     3061 atgatcagaa tcgacgccca gaaacatttg attttgattc caagatttgg gttataacac
     3121 aggaggaaaa gtagagatga ataaccaaaa aagcttactt caaaaaggag caatcttaag
     3181 tatttcacta atgttaacaa gctctcaagc aattaatggt gttattccac aaatgaaaca
     3241 gtctttgggg atatcacaaa gtcaaagtga acttttagga actgcaccaa gtataactgt
     3301 tattttgttt atcttattat ctagttactt tgccaaaaga ataggaatga aaaagacaat
     3361 aattttaggt ttattattag ctggtatagg aggaattatt ccagtattta cagctacctt
     3421 ccaaaccgtt cttattagtc gagtaatatt aggtgccggt ttaggagtat ataattcatt
     3481 ggctgtgaca tatatcagct ctttatactc tggcaatact agagcaacgc tattaggtat
     3541 tagaaattca atggaagctt taggtcagac aatccttatt tttcttgctg gagttttagt
     3601 gaacattaat tggacggctt cgtttttagt ctatgcaatt gcgtttcctg tagctctctt
     3661 attcgcgcta aaagttcctg aaattagaga tgaaaatagt gacatacctg aaaatcatgt
     3721 aaaagaaaag atgaatccaa tggtttttgc cctagttcta tttgcaatct tactcgtaat
     3781 gaatagtatt gctatttctg tacgatttgc atcaattgca actgaaatta aaggggtaaa
     3841 ctttaatgct agtaactatt tagctctaat gcctatctta ggaatactag caggatttat
     3901 gtttggacca ataaataagt ggataggaaa aggaacccta tacttgggaa ttatattctt
     3961 tataatttca aatttgttaa ttgctgtgtc aaacggtaat atgacgttcc tgctaacggg
     4021 tttattttta tcaagtataa caggatcatg gtgcttccca tttatcttta gtaacttaga
     4081 taaagtcact acaaagaata caattaattt tgctacttca ttgattttta ttggctgtaa
     4141 tattggtaat tttatagctc ctattgctat gcaattagca caatttctaa caagaagtac
     4201 aaatttgact gctccatttt ttgtattcgc aggaatattt attgtgatcc tatttgtaac
     4261 attttttgcg acaaataaaa aaaatactag agt
//
LOCUS       DAZKCH010000137         4282 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000137 DAZKCH010000000
VERSION     DAZKCH010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.143"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(37..1257)
                     /locus_tag="ACG84X_002710"
     CDS             complement(37..1257)
                     /locus_tag="ACG84X_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFP9128513.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1888)
                     /locus_tag="ACG84X_002711"
     CDS             complement(1277..1888)
                     /locus_tag="ACG84X_002711"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFP9128514.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="ACG84X_002712"
     CDS             complement(1931..2863)
                     /locus_tag="ACG84X_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFP9128515.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3284..4144)
                     /locus_tag="ACG84X_002713"
     CDS             complement(3284..4144)
                     /locus_tag="ACG84X_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9128516.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1219 a          861 c          701 g         1501 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttgtcaaccg attttatata tttttttata taataaggta
     3001 attttaatat aaaattttat attgtaaaaa aacaaataag ggaaacaaac aacacatttt
     3061 tgtgtgttgc ttatttccct ctaactatcg ttttctattt gatggttaac ctacttaaaa
     3121 taaatactgc aacgacaaac ggagatcaag catgctttgt aacgtatttt acgataatta
     3181 cgactttatt ttattactct atcttgctgc catacccgtc tatccctaat catctttggt
     3241 gaattttttc aaagttagca taacaaaaat aagtattttt tccttagtta atcaatagta
     3301 tcattttttt catatgattt aattcatcaa ttaatttttt gtttttatta attttagcaa
     3361 aagctagtgc atcttgaatc aattcgagca cttctgcctt cgacttattt ttagcctgtg
     3421 cgttcttcgc taattgggca gcagctcgtg ctaagtaata agtcaaatgg ttatccgaac
     3481 aaatatcgat tgcgtaattt agtagtgcat cacttgtttc caaatcaccg tcttgcgcaa
     3541 aaaaaacacc acaatgaaag acgatattta acacccgcca gatatcttct gttgtacgaa
     3601 tcggatacgt ataaattttt tcaaacactc gattgaaata aacttctgct ttttccaact
     3661 ctttttctct agcatagacc attccaatac ctgtatatgc caataaacga aacaacgtgt
     3721 tggctgtttc tgccatcaac aactgatcaa aatggaacaa cacatccgta attggtgcat
     3781 tcgtaaaaat catttcaaat ccttttagat agtagtaacg tgcaatcagc tcagactcgt
     3841 caattacctt gggatcaatg gctgctaaaa tctgtgtcaa ttgttcatat tcactcgtaa
     3901 tcagtgaaaa ctctgctttt tctagctgtt catcaagttg tgtattgatc acgttcatcg
     3961 aagaaaaaag ttcaactaac ggaagattga ttcgattaca taatttgatt aaaattttta
     4021 acgaagggac ttgaccattg ttctcaaatt tacttaatgt tgcttgtgta caaattcctt
     4081 cagacacttc tttttgagat aagttggcag cctttcttgc cgtaataaat ttttcaatgt
     4141 tcattatttt ctctccaatc agacctcaca cgaaaatcat ttctgtctcg attttagcat
     4201 gttttctttg ggaatgcttt aggttctgtt gcaaagtttt aaataaagaa taaagtccct
     4261 tacggtatct atgatttaag ct
//
LOCUS       DAZKCH010000138         4260 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000138 DAZKCH010000000
VERSION     DAZKCH010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.144"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            234..1559
                     /locus_tag="ACG84X_002714"
     CDS             234..1559
                     /locus_tag="ACG84X_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFP9128517.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            1552..1902
                     /locus_tag="ACG84X_002715"
     CDS             1552..1902
                     /locus_tag="ACG84X_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128518.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            1899..2069
                     /locus_tag="ACG84X_002716"
     CDS             1899..2069
                     /locus_tag="ACG84X_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128519.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
     gene            complement(2973..3248)
                     /gene="prgO"
                     /locus_tag="ACG84X_002717"
     CDS             complement(2973..3248)
                     /gene="prgO"
                     /locus_tag="ACG84X_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFP9128520.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(3220..4173)
                     /locus_tag="ACG84X_002718"
     CDS             complement(3220..4173)
                     /locus_tag="ACG84X_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9128521.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
BASE COUNT         1447 a          705 c          747 g         1361 t
ORIGIN      
        1 tttttttcta atataactaa gcaaaactgg ataatacgac acttattttc aaattttcac
       61 aagactaata gtaaatatcc atttaataaa gtgatacaat gtgttgattt tacaaatcaa
      121 cagaagaagt agggaaataa cttacctatg cttctttttt tgtacattta atcgattctt
      181 ctttacaaaa acgaacgtat gtttgtataa tgtggaagaa tggagtgtta tttatgatgg
      241 attattcaaa agagccagta aatgattact ttttgatcga tatgaaaagc ttttacgcaa
      301 gtgtcgaatg tatagaaagg aatttagatc cattaacgac tgaattagtc gtcatgagtc
      361 gagcggataa tacaggatca gggttgattt tagcttcttc accagctgca aagaagaagt
      421 acggtatttc taatgtcagt cgaccacgag atctaccgca accttttcct aaaacgttac
      481 atgtcgttcc accacgcatg aatctctata ttaagcgaaa tatgcaggta aacaatattt
      541 tcagaaggta tgtagcagac gaagatttat tgatttactc gatcgatgaa tcgatcttaa
      601 aagtgaccag atcaatgaat ctttttacga ctgaaggaac aagaagtcaa cggagaaaga
      661 agctggctca aatgatccag gagaatatta aagaagagct aggattgctt gctacagtag
      721 gtgtcggaga taatccctta ttagctaaac ttgctttaga caatgaagca aaacataatg
      781 atggattcct tgctgaatgg acgtatcaaa atgttcctga taaagtatgg aatattcctg
      841 aaatgacaga cctttggggt attggatctc gaatgaaaaa aagactcaac caaattggta
      901 tcatgagtat taaagactta gctaattgga atccatacac tattaagagc catttaggtg
      961 tgattggctt acagctgtat tttcatgcga acgggatcga tcgaacagat atagcgatcc
     1021 caccagaacc gacaaaggaa aaatcatatg gtaattcaca agtgttacca cgagattata
     1081 ccaggagaaa tgaaatcgaa ctggtggtaa aagaaatggc ggaacaagta gctattcgta
     1141 tcaggcaaca taactgtaaa acaggttgtg tccatttata cattggcacg tcgatcttag
     1201 aaacgagacc aggtttttca caccagatga agatccctat aacagataat acaaaggaat
     1261 tgcagaatta ctgtcttttc ttgtttgata agtattatga aggacaagaa gtaaggcacg
     1321 ttggaataac ctatagcaag cttgtgtaca ctgattcgct tcagctggat ttatttagtg
     1381 atccacaaaa gcaaattgac gaagaaaatt tagataaaat tattgacaag attcggcaaa
     1441 aatatggttt tacgtcgatt gtacatgctt cttctatgtt agaaggcgct cgtagtatta
     1501 ctagaagtac attggttggt ggccatgcag gcggcgcagg agggcttaaa aatgattgat
     1561 tataatgatc gtggacgttt aaagtgggca ggtttttatt tatctgatca tactgaaaaa
     1621 attgatgccg acaatgaaca acgagccaat caaaatttgg caaaagaaca aatgacgact
     1681 gaagaggttg cggaagtatt gaacgctgca gtcataaaaa atagatcagt atgtattcaa
     1741 aaagaagaac gaaacgctga aggatactat ccagaagata ttgttagcaa gatcttaggt
     1801 agtgatgagc tggggatcta cgttggaaaa aacaaagttc actacgacga aatacgtcat
     1861 atcgaatttt accaggataa taaatggggt cgattagaat gaacattatc cagcaatatg
     1921 agctaaagta tataaccttt gatcagctat cagaagagat ttggggttat ggccagcgtt
     1981 tgataaatga ggttggtgtt gaacgcttct ctttctatgt agaagctgca gcaggatacc
     2041 ataaatacga atactatatt ggctattaaa gtgcaataaa attatatttc ttttatgttt
     2101 tacattttgt atcaattctg ataaaattac ctataggtaa ttaaaaaata taaaaaaact
     2161 agttacaacc ttaggacgtt gtaactagct tgaagcatac tagagctaac taaaatagca
     2221 ctagaaagca atgttaaacc cgtccaacaa acttgattta acattgagac cagcttattc
     2281 agctaaatat agttgaataa gcttcttttg ttttaaaaaa acaaaaggtg tactacgaat
     2341 aacgcaagta aaagaaatac tattacaacc agtaggctac aagtaagtat tactaaacat
     2401 tgcgtagtta gaacctttgc tctattgtct aaagccacaa aattagagat cagctttatg
     2461 atgctaagag cgagctgcat ccatgcggac ataggttctt ttgacactat taattctcct
     2521 ttttaggata agggaaattg ctagtagttt tttcattagc accatccccc ttcatttgat
     2581 tgagtctagt gctgctgtga tagtttgctg tttaatatgc ttacattctt attataacat
     2641 aaatgaaaca aacacatggt tagaggtcgt atcaatcaaa atagtgtctc acaaacgatt
     2701 tattacttac tcctgctgac taacggactg ttcttcagta actgtaacta tatgtttgtt
     2761 aaaaccacca ttacctgtag ataaaaacca atatatttac tatactcact atattaaata
     2821 tatttagtat agtaaaaact agaaacaata aaatttgtga atgttgtata cccccaaaca
     2881 atacacatat tttgaaggat taggattaat aaagctaaaa atatagtaag tatactaaat
     2941 atatttacta tatctagtat acttactata ttttaatctt ttgatcgtct attatatata
     3001 atccgttcct cgtcgtttaa agtatcaaca taggcgtcca ttgcaagttt gactatttca
     3061 tacataggaa tatcttttgc ataactaaga tcccgaatgg tttttagtac gggaggatct
     3121 acttgaactg gttttctttc tttcgcagtg tactttcgtt cccctaactc gacattaata
     3181 tcatctttaa ttgaaatatc ttcagcacca attttcttct tatctttgtt cgttggtaat
     3241 aatgccattt agtttaatct cctttccaag aggtaggata tgattggcca ttgagtcagc
     3301 atatttaggt gtataatcaa atccttcaat atcaccatgt tgttcatagt attcaattct
     3361 ttcttctaat tctgtaaaga tgtctgcaaa aatagcccac catcttcgat ctacataatc
     3421 atttaattgg ataccattct caccatacat ttctaaccga tccgagcctt taacaatgct
     3481 tttaaaaatg tttgattcac catacttatc aattgttttt tgatagtttg cgtgttgaga
     3541 ggaacgtcgc actgagaaaa gaacaggcaa aattccaatg atttgaagat gagactcttc
     3601 aaaattcgtg acaatcggaa ctaaaacttt attaataaaa tcttctgttc cttccattgc
     3661 gtaccgtttt aattcttgca ttgcaataat ataatctgca gcagttaaga atgcacgaac
     3721 cacattatct gttgatggtg ggcagtcgat aaagatataa tcgaaatttt ttctcaattc
     3781 ttctaaaggt ttaatgaagg ccaatgatct cttacgacga tcaggatatt tttcggacaa
     3841 gtattcatta agttcttcag atccaggaga gccagccata atatataaat gtggacttac
     3901 ttgagtaata cctgaaaccc agtccccttt tttgattgct gcagacatgg atcgatcaaa
     3961 gctagtaatt tgatacgttg atccaatgtt ggaagtagta tttctttgtt ggtcataatc
     4021 aattagcaac acgtcttttt caaaaagttg actagaaaca atcgctaata aatcattgtc
     4081 tgtagtctta ccaatgccgc cttttctacc tgtaagcatt acaacttttc ctagtttatc
     4141 tgatgtttta aatgcagtcc gtaagttttc catagttccc tccaatttcc tatactaaat
     4201 atatttagta tacttcatat acttaatata ttcgatatat ctaatatact ccaaattgat
//
LOCUS       DAZKCH010000139         4176 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000139 DAZKCH010000000
VERSION     DAZKCH010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.145"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..696
                     /locus_tag="ACG84X_002719"
     CDS             <1..696
                     /locus_tag="ACG84X_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9128522.1"
                     /translation="LKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYND
                     AQGIVLMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNM
                     YVFLILSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQAL
                     AGGVGGWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDK
                     VLENCELLKQKHK"
     gene            706..1500
                     /locus_tag="ACG84X_002720"
     CDS             706..1500
                     /locus_tag="ACG84X_002720"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9128523.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            1513..3279
                     /locus_tag="ACG84X_002721"
     CDS             1513..3279
                     /locus_tag="ACG84X_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HFP9128524.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            3302..>4176
                     /locus_tag="ACG84X_002722"
     CDS             3302..>4176
                     /locus_tag="ACG84X_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding domain-containing protein"
                     /protein_id="HFP9128525.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKP"
BASE COUNT         1505 a          495 c          818 g         1358 t
ORIGIN      
        1 ttaaaatctt taaaagggtt agttaaaaat agggcattac tttctataat tggtgcggct
       61 attttcttac tccttgctca attattaatt atgagtatga ataattatgt atttcctgat
      121 tactataatg atgcacaggg aatagtttta atgaatttta tcaatcctat tttggtttta
      181 atagttgttt cgcctttaac tttgttttta agtaaaaaat atggaaaaaa agaactggca
      241 tcagtaggaa tgttcttttc agcaatagta tatttgatct tatttttgat aaaagctagt
      301 aatatgtatg tattcttaat tcttagttcg gttggctata tgggtttggg tgtgtttaat
      361 actgttattt gggcaaatat tactgatgtt attgatgatc aagaagtaaa gtctgatcaa
      421 agagaagatg ggaccgtata tgcggtatat tcttttgcta gaaaaatagg tcaagctcta
      481 gctggaggcg tcggaggttg gactctttct attataggct atgactcttt agcaaatgta
      541 caaacgggag atgttttaga aaagttatat aacgcttcaa cattaattcc atcaatttgt
      601 tttctgattg taggattaat tttatttttc ctttatccat tatctaaaga taaagtctta
      661 gaaaattgcg agcttttaaa acaaaaacat aaataggaga gaaatatgaa taattggata
      721 ttttgtattg attcagatgg ctgtgttatg gatacgatga cttataaaca caatctcttt
      781 ttcggaccaa ttgctgcaga gatttttgat gttcatcata gagaaaaatt cctacaggat
      841 tggaataata ttaatttata ttcagagact cgtggaataa acagattttt aggtttagtt
      901 aaaacattag aaaaaaatga tgtaacatcg attaatcgat taaagcactg ggtatctcta
      961 acaaaagaat tgtctaatcc atctttgaag agggaaatag aatattctca gtcagaggat
     1021 ttattaaaag ctttaaaatg gtcggaagaa gtcaatcaac agattagtca agcaaaagga
     1081 ttagataaac cctttttaag tgctagagat actataaaag ctctgaaaaa atatgggaag
     1141 ataattattg taagctcagc taataaggaa gctgttcaag aagaatggga aagacatgaa
     1201 ttattatcat tagttgatga actgtgttgt caagataaag gaaaaaaaga agatattatt
     1261 cgaagtgtaa ttgaaaatgg ttgtgatttg gataagatat taatgattgg tgattctcct
     1321 ggtgatctag aagctgcaaa taaaaataaa gttttctttt atcctatttt ggtcaataaa
     1381 gaaaaagaat catgggaaaa cttaagaact gatgttttat ttaaatgttt atcgggagat
     1441 tatgtagata ttgaacaaaa atatatagat actttttgga aaaatcttac taataagtag
     1501 aggagaaaga aaatgactat aaaagtagat ttacgaaaaa aaccatataa tttagatgaa
     1561 gatgctattt cttggattga agagacgatt gattctatga ctttggaaga aaaaataggt
     1621 caattgtttg ttaatatggg atctagtcgt gataaaaatt acttgagtaa tatggtcaat
     1681 cagtaccata ttggagctgt acgatataat ccaggaactg ctgatgaggt atatgatcaa
     1741 aactatatct tacaaacaga aagtaaaatt cctctattaa ttgctgctaa tacggaagca
     1801 ggtggtaacg gagcttgtac agatggtact gaagttggtg tagaagtaaa aattggtgca
     1861 acaaatgatg cgaaatatgc ttatgaatta gggagagttt ctgggattga agcatcggct
     1921 attggatgta actggagttt tgctcctatt gtagatatta atagaaattg gagaaatcct
     1981 atcatttcta gtcgatcttt tggacaaaac cctgataaag ttttagaact tagtttagct
     2041 tatatgaaag gtattcagga gagtggaatt ttgcctgcag ctaaacattt ccctggtgac
     2101 ggtattgacg aacgagatca gcatctatct tttagtatta atagtttagg tacggaagaa
     2161 tgggataatt cttttggaaa agtatactca ggcttaatag aagctggatt accttcaatt
     2221 atggcaggtc atatccatat gccagcttat tcaaaacatt ttaatcctga tctgaaagat
     2281 gaagatttac ttcctgcaac tttatcaaaa gaattaatca ctgacttact tagaggaaaa
     2341 ctcggattta atggattagt agttactgat gctagtcata tgttaggaat gactggggca
     2401 atgaaacgat cagaattatt gcccacttct attgcagctg gatgtgatct atttctattt
     2461 tttaatgatc cagatgaaga ctttaattat atgatggaag gctatcgtaa aggaattatc
     2521 actgatgatc ggttattaga tgccttaaaa agaattttag ggttaaaagc taaattggga
     2581 ttacacaaaa aagcaaaaga acaaatttta ttacctaagc aagaagctct ggaaaaaatt
     2641 ggtttaattg aaaataaatc aatttttaaa gaggtggctg accaagcaat tacattagtt
     2701 aaagataaac aagatatttg gcctattgta ccagaaaaat ataaaaggat tttactagta
     2761 gatgtacatg gggtaaaagg tgggtttggt gaagtagttg ctggaaatag acctcaagcc
     2821 attgatttat tgaaacagat tttgtcagca aaaggatttg aagttgaaaa atacatttca
     2881 cctgaagaag aattgaaagg attatcgcaa gaagaaaaaa ttaaaaatat agctggaata
     2941 tatgctgcta agagaccaat taaaaattta actaaaaaat atgacttgat cattaatata
     3001 gctaatgtta atccaggcac agttcaacga attgtctggc cagcaagtaa aggaactccg
     3061 gatataccgt tttacattca tgaaattcca acaatttttg tatctgtaca gtgtccgttt
     3121 catttggctg atgtacctca agtaaagact tatattaata cttatgatgg aaaacaagaa
     3181 actttagaaa tattggtgga caaactaatg ggtctttctg aatttaaggg agtaagtcca
     3241 atagatgctt attgtggttt aaaggataca tttatttaat atttagatag gagtggttta
     3301 tatgttgtat cccattatga cagagacgag gcaagtaatt gacttaagcg gtctctggag
     3361 atttaaatta gatacaaatg atgacttaca ggaagaactt gctttagaac caataaatga
     3421 aaaagagagt tatccgattt cagttccctc ttcttataat gatttatttg aaacagagaa
     3481 cattagaaat catgttggat gggtgtggta tgaaaaagaa gtgactcttc ctaaaagatt
     3541 attagaagaa agattagttc ttcgttttgg atctgcaaca catgaagcaa aagttttttt
     3601 gaatggaaag tttattactc aacacaaagg tgggtttaca ccatttgagt ctgaaattaa
     3661 tcggtttgta aaagacggga ataatcgaat tacagttgct gtaaacaata ttattgacga
     3721 tagtacttta cctgtgggga ttatgaagga aacagtacag gaaaatgggg atataaaaaa
     3781 ggaaaactta gttaattttg atttcttcaa ttatgcaggt attcatagac ctgttaagtt
     3841 atatacaact ccgaaagact atataagtga tattactatt aatacaagaa taactgattt
     3901 ggatgcaagt gtagaattca atatcgatac agaatggacc ggaaaaatct taatagcgat
     3961 atatgacgaa gaggctcaac ttgtagctga agctgaagga aagaaaggaa tgattcagct
     4021 taagaatcca attttttggg aacctctaga cgcttattta tatagtatga aaattagttt
     4081 aattgatgat aataaagtga tcgataccta tacagaagaa tttggtattc gcagtgttca
     4141 ggttaccaat ggcaaatttt tgattaataa taaacc
//
LOCUS       DAZKCH010000140         4041 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000140 DAZKCH010000000
VERSION     DAZKCH010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4041
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.146"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            179..775
                     /locus_tag="ACG84X_002723"
     CDS             179..775
                     /locus_tag="ACG84X_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFP9128526.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="ACG84X_002724"
     CDS             899..2698
                     /locus_tag="ACG84X_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFP9128527.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="ACG84X_002725"
     CDS             complement(2976..3188)
                     /locus_tag="ACG84X_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128528.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="ACG84X_002726"
     CDS             3650..3799
                     /locus_tag="ACG84X_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128529.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
BASE COUNT         1189 a          689 c          711 g         1452 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gagatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat a
//
LOCUS       DAZKCH010000141         4006 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000141 DAZKCH010000000
VERSION     DAZKCH010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.147"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..497
                     /locus_tag="ACG84X_002727"
     CDS             <1..497
                     /locus_tag="ACG84X_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128530.1"
                     /translation="SYLIVCLIIIICLHHLFLSKTIPRYSKNKKAEKFCLLLNKFTLI
                     APILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFLMSLKPPKSISLCL
                     VINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYIGYFPNKNNNFYFY
                     RNKL"
     gene            complement(623..1300)
                     /gene="nth"
                     /locus_tag="ACG84X_002728"
     CDS             complement(623..1300)
                     /gene="nth"
                     /locus_tag="ACG84X_002728"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFP9128531.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1307..2005)
                     /locus_tag="ACG84X_002729"
     CDS             complement(1307..2005)
                     /locus_tag="ACG84X_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFP9128532.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2273..3457
                     /locus_tag="ACG84X_002730"
     CDS             2273..3457
                     /locus_tag="ACG84X_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFP9128533.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3463..3906)
                     /locus_tag="ACG84X_002731"
     CDS             complement(3463..3906)
                     /locus_tag="ACG84X_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFP9128534.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
BASE COUNT         1053 a          783 c          651 g         1519 t
ORIGIN      
        1 tgagttatct gatagtatgc ttaattatca taatttgtct gcaccatctt tttttatcga
       61 aaacaatacc tcgttattcc aagaataaaa aagctgaaaa attttgttta ttattaaata
      121 aatttacttt aattgctcct atccttgcat ttattatttt ttctgtactt ttaagcacta
      181 ctcttaaagg aaaatttatg gaaagaagct ctcatgcaat gattctcact tttttatggt
      241 tgttgttcac cagaatctat atttttctga tgagcctgaa accgcccaaa tccattagtt
      301 tatgtttagt tataaatggt atttttttat tatcacttat catttttatt acacctttag
      361 atagatacgt cacttattta tataatcctt tggaatactg gacttatttt ataggtatat
      421 tggaaggcat tattttctac atcgggtatt ttcccaataa aaataacaac ttttattttt
      481 atcgcaataa attgtaataa gttaccatcc tagctactga gtatgtacat ttactttttc
      541 atgcaaaaaa gataaacgaa acagcttttc tccataataa caagataatt catacattta
      601 tttgcaatta aagaaaccac gtctacaggc gtggtttctt ttttagcgcc ttttctttta
      661 gacgcatccg atttttccca tcttgacata ttgatagcaa aggacatacc tcgcacttgg
      721 gatttcttgc cgtgcaatga tatctaccaa aaaaaatcag tgtatgatgt gtctttaccc
      781 ataattcttg tggtactttc cgcatcagtg tttcttctac ttccatgacc gtagcatcta
      841 gtttgcagat cctcaggcgt tttgagacac gttccacgtg ggtatctact gcgattgctg
      901 gtatcccgaa tgcatccccc aatacgacat ttgctgtctt tctgcctaca ccaggaagag
      961 acatcaattc ttctcttgac gttggcactt gcccatcgaa acgttcaatc agctgctgtg
     1021 cacacgcttt gatgtttttt gctttatttc gatacaaacc aatcgttttt attttaagaa
     1081 tgatttcatc gattgaagct tctgctaacg catcgggtgt cggaaaagag gcaaacaaat
     1141 ctggcgttgc tttattcact gatacatctg tcgcctgggc acttaagatc actgcaatca
     1201 ataactcaaa tggattattg tgcttgagtt ctccatgtgc ttcgggaaac attccataca
     1261 tcgtttctag agcttccatt gttttttgtt tgcttaacat attccgctac tcctccaacc
     1321 aatttttcag tgagactttc ggcaattctt cttgttgagc tgactgttct acttctcttt
     1381 gaagaagctg ctgttttctt cgtttttggt cttcttccac ttgttgtttt gtacgtagat
     1441 tttttctttc ccacgatagc aaaatgcggt caacgtaatt aaaactataa gcctgattta
     1501 atacggcttc ccgcagtgct agcttcaaaa tttccggctg ataatggtct tcttctagcc
     1561 attgtccgat ccgctggaac tcgatcgaag aaagcgggcg tccaaattct tgttcaaata
     1621 attgatacac tgactggatt tctttttctt gtgttttttc ttcgtatttt ttttcttgtg
     1681 tttttaaata ctcacctaat agatcataga tggggtaaag attatatcga tctgcttttt
     1741 taccgttgac aatcgtcgtt tctatcttga taaatccatt tgttacgaga cgatccagta
     1801 tttgaaaaat ctgatcttgt ttgattccca tatccatagc aatcatctgc aaatcaggga
     1861 aagtatctcc ttcaagctgt gccatatgca actgtagaac aaataaaaat tcttcagatt
     1921 gtagaccgat cctatgataa tttttaagta aaagattaga tatgactgtt tgtccagcgc
     1981 ttaagtaatt ttctaaattc aacatgattt ctcctccgct caatcacagt atacgtaaaa
     2041 aaaacatggg aagcaagaac aggtttcttt tctatttact tcactgatcg gtcagattta
     2101 caatgtcgtc tacttgattt ttgtttgttc atgtttttga tgcgtatctt cacttttcgg
     2161 aataaataaa ttaagtagat ttcgctgttc cttagaatgt tgacaaggaa acaaaattac
     2221 tatacactat ttttgtttcc aagttaacat tattgcataa aggagttttt acatgtacag
     2281 tttcacaaat aaacattcta aagtttttgg atacgtctct gtcttattca ctggattagg
     2341 atttactatc gtcagtcctg tacttccgtt tttaacgctg ccttattctc actccataca
     2401 tcagcaagct ttctatatca ctttgctcat gtctgtttat gctctagctg ccttcttatc
     2461 tgcccccatt ctcggtagct taagtgatca ttttgggcgt catccgatcc ttattatcag
     2521 tttattagga tcaagtatcg gatatttgct ttttggttta ggaaattcga tatggatgtt
     2581 gttccttggt cgtatcattg aaggattgac ggcaggagaa atctccacct tatatgctta
     2641 ctttgccgac atcacggaac ctaatgaaag aaccaaagtt tttggatgga tgggtgcttt
     2701 agtcggtata ggaacaacgc tgggtcctat tatagggggt ctattagctg agttggggaa
     2761 ttctgttcct atatttattg gagcactctt tactttctta aatgccgttt atggctacac
     2821 atttatgcta gaaagccttc caataaaaaa acgttcagta gatttaagtt tctcccatgt
     2881 aagacctttt caccaattac aacaattatt caagatttca tccgttattc ctttattgac
     2941 agcaggtttt gctgtttggt tggcagctgg ctctcttcaa tctatctttt ctcaattttc
     3001 gattgacgcc tttcagtgga aggctgggtt ggttggttta agcttctctt tgattggaat
     3061 cttggatact gtctcgcaat tgttcattat gcctcgattg ctcaaaaaat tttcagaaca
     3121 gcagatcaca agaataggga tgttcagtga aatcctcgcc tatctattca tcacattatc
     3181 tggaattctt ctactgccga ttttgttttt atttgggatt atctgttatg gtttcggtga
     3241 ttctattttt actcctgtat tcaatggcca actatccaat tctgtctcag ataaccagca
     3301 aggtcttgta atgggcggta cccaaagtat acaatctcta tcgcgcgtca tcggcccgct
     3361 aatcgcagga cagctttatg ctgcagcacc atttcttccg acggtattcg gatttttgct
     3421 tatgattttt gcctattatc actacaataa aaaatagtag cttcatttgc tacttcgtat
     3481 aaattctctg tatcgaccga taaaacgaaa tactgtgtca aattcttctt ttgacatatt
     3541 ttcaaataca gtagcatctc gctgtaccca tttttgatgg agttgctcgt gtctattcct
     3601 tattttttgt ccgattggcg tcaattgaaa atagatttct tttttattct cttcgctttg
     3661 ataagtgttt atgatccctc tagctatcag tttttttgtt agcttactga tggctcctct
     3721 agtcatgtaa ctagcattcg ctaattttgt cacgttagga tcagggattt tcccgatatg
     3781 ttcaatcact tctagttcat ttagagtaaa tcctgcaaat tctttttcca tttctggttt
     3841 attacgatga ataatctcat tagctaaatc cagatattct tctattagca gttgtctttt
     3901 atccatttct acaccttctt tttctttcat tatattgttt ttttgtttcc tattcaacaa
     3961 agataaaaat attttgtagg aaaacccaat ctgaaaccaa gaaaaa
//
LOCUS       DAZKCH010000142         3940 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000142 DAZKCH010000000
VERSION     DAZKCH010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.148"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            477..1970
                     /locus_tag="ACG84X_002732"
     CDS             477..1970
                     /locus_tag="ACG84X_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFP9128535.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            2105..2401
                     /locus_tag="ACG84X_002733"
     CDS             2105..2401
                     /locus_tag="ACG84X_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFP9128536.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            2502..3353
                     /locus_tag="ACG84X_002734"
     CDS             2502..3353
                     /locus_tag="ACG84X_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128537.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            3374..3586
                     /locus_tag="ACG84X_002735"
     CDS             3374..3586
                     /locus_tag="ACG84X_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128538.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         1395 a          575 c          798 g         1172 t
ORIGIN      
        1 gctatattca gtatatcaga tatattcaaa atgtcaaaat atatttgtgc gttttgcgtt
       61 gacaatttag agtgaaaaga ggtaaactta attctataga aaccacagat aattcactat
      121 ttacaaagta gcaaaagcag tggtactctt taaacagaaa aattacataa aaaaaagaga
      181 cggaaataat tgattttagc agaatcaatt atttctgaat cacatggtta ggacatgtgt
      241 tcacgctcgt ctcaagaata tgtaagtagc taccaactac ttatattaaa agttgatcgg
      301 ataccttttc cgattgcctt tattctacca aaaaaaggcg agcaactcaa cagaagaacg
      361 tttatttagt gtacttaaat taaatattct taaacactga agagagaaca catactatgg
      421 ctgagattaa agctaaactg tgttctcttt ttgtttgaga aaggacgtta caatcgatgt
      481 tgagcgaaat ttattcagct attcttaaaa acggcttacg tacatacaaa tatcgaaaca
      541 gcaccatgaa acctgcaggt catattgatt ccagtaggag tggtgctatc tttgcgtacc
      601 gtagcaagca attaatgaat gttgggcgtg gtatggtcat tacttcggaa gaagctattt
      661 tagagaacga aaagaaacta acgcattgga cacctaatac ctatcgcttt ggtacttatg
      721 cggatgatta tcgaacagtg gttaaaggtc attctgagaa aaacttaagt caaatcaaca
      781 catttgtagt tgatatcgat tcaaaagaga accatcaagg cgaaattatt ttagcctgtt
      841 tagatcaagt gggctacatg ccaacgctaa ttttagaatc agatcatggt tatcaagttt
      901 attttgtact aaagacacca ggctatgtca caaagaaaag caatttcaag gtgatcgatg
      961 tagcaaaaaa aatttcaaaa acaattcgtc tacagttggc tgaaaaattg tccggagtgg
     1021 atctaggatg taaccacttc ggaattgctc gattcccaca agaaaataat attgttttta
     1081 aagaaatgaa ctatcagtat tcttttgctg actggattca atggtcgatg aagcttgaat
     1141 cagatcaaaa aacaaaagaa gatcgagaac gaaaactaat tgtctttcct gagaaaaaag
     1201 aaattcgtca agtagatgaa ccgtggttcg atatgttact tcataaagca aacatcgtcg
     1261 gcggagaagg acgtcttggt cgaaataatg tgattttcac gctttcttta gcttattact
     1321 cttcaggtta tgcattggat acttgcgaat acaatatgtt cacattcaac gaacggttac
     1381 aggaaccgct atctgaagca gaattagtaa agattgtacg tagtgcttat tctggtaatt
     1441 atcaagcagc aagcagagaa ttcattattg aattgtgcca gcaatgggtt tcaccaacct
     1501 taaaaaataa tgatctgttc attcaacgac gtggctggtg gaaatttaaa aagccacgag
     1561 atcaaagaaa atatagtcat aaaaatgaat ggaaagaaga tctattggct tatctaagcg
     1621 aaaaaagtct tgctagtgag ccttatttga acctgtcaaa aaaagaattg gcttcacaac
     1681 taacgatgcc caagcgaaca cttgataaga tcttaaatga gttacgagag gagaataaag
     1741 tcttctacaa ggtaacacga ggaagaaatg gcggaatgat cattgcttca gtcaaaacgt
     1801 tgttcgcgag ggttattcaa ctaagtaaag aaaagagact agattattca acaaggatca
     1861 cagaggtatt tggactcaac gagagcttag tagaagagac atttagacaa ttatcaaccc
     1921 ccttgaaccc tcttaaagaa gtgaatcttt ttgaagtaga tacaggttga aaaataaaag
     1981 gtgcaaattg ccctatacaa tatatctatg atacttctgt aggtgttgct ccctttgcct
     2041 agctacgtgt aggtggtata cttataactg cgtatgcagt cttatgtatc atggaggaag
     2101 ttgtatgtcg ttaaaaaatt atgtctattc acatcctgtt aatgtgttta tcattggtcg
     2161 tttgggatta tctgtggaag tgttctgtga gctttatggt tttaagcagg ggactttgtc
     2221 ttcttgggtt accagggaaa aaacagttgc ttctttgccg attgagtttc ttcatgggtt
     2281 gtccttagct tctggggaga ctatggatca ggtatatgat tgtttgtgtg tgttagagca
     2341 ggagtatatt gagtataaaa tagctaacga gttaagaaaa aggaagaagt atatccagta
     2401 gtagttttta tttacttaaa aaattggttc attgagcaac ctatcgctgc taaagtagca
     2461 aaggaaaacg ttaaaggaaa gaatttaggg aagaaatcga aatgaaatcg gacgactgga
     2521 ttgaacacac ctggcttcct ctgaaaagaa atagcaaacg aaagaaattt tgggtattgc
     2581 aattatggcc attaggaaaa ctttgtagtt acggggcacg acttattctt gatttaaccg
     2641 tttactcgat tggagtattt ggaacggctt attacttgat aaatgatccc aataggattg
     2701 cagcatcaga catttttaca gtgctaatga cgttgatttt tgtcatgcta ttgtctattt
     2761 ttactcaatt agtcatgcaa tttaccaggc aaaaattaac agcaggaaaa cttttcaaaa
     2821 gcctattcga tttaattgtt gtaaatgcaa ttctagcgac tttaataaaa caaattgaac
     2881 aatctggaag aacaacaaaa ggagtgaagg attttttatt gacgtttatt cactttgtaa
     2941 atggacacat gtatttgttt gaagtgggta ttattctctt ttttgtcggg tatgtatcca
     3001 cgaaacttat taaacgttca attgaaaaag aaattgaaat tgacctgatt ccgacacttc
     3061 ttggttatga gtacaatgtt gattttggaa gatatgacga attgatcaat acggatatcg
     3121 ttcacacgag tatccatgaa tctactgtta agggcatcag atctatttta aaaaatggcc
     3181 aggaaatgaa agcaatagat cgaagaaaag agatctacaa tttttatgaa gtcgaagcaa
     3241 gcctacgata tggcatcgga aaattgtggt tagatggaag taatattcgt caaaacaaac
     3301 catacatttt ttggaacagt agtgatttag aacttccaat gaaagataaa taattatgga
     3361 gaatcgtttg aaaatgattc ctctatacag gattgtgctt atagttggca tggagttaaa
     3421 aaccttaaag aaggagcagt tattcaaagt gaaagaacgt cataatcagt tactatgtag
     3481 taaaacgggt acgatgaaca ttgaataccg aacagaatat ttagaattaa cgaatcaaac
     3541 tgattttttg ttgattcgaa agcaacaaga gcaagaaaaa aattaatggc tacttatagc
     3601 caattgattg atgaatggga acaattcaag gaatctaaaa ttccagaacg tctctaaaag
     3661 cctttatttg taaagagcat aaggaaacgt gggaacactt tttaaaaaaa gtgttccaat
     3721 aggctgtgcc tattacgttt ctcaaaaata aatgtgggaa caaaatattt aaaaatagga
     3781 tagtgaaagg atagtgaagg atagtaaaag gagggtagta ggatagcaaa aaggataggc
     3841 tccttttcgc tatccttttt aaattggagg aattaatatg gaagtaagaa taagaaatgt
     3901 ggatgagaaa atcgtaagag aaattgatcg aagatgtgac
//
LOCUS       DAZKCH010000143         3937 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000143 DAZKCH010000000
VERSION     DAZKCH010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.149"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(587..1144)
                     /locus_tag="ACG84X_002736"
     CDS             complement(587..1144)
                     /locus_tag="ACG84X_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128539.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1323..1934)
                     /locus_tag="ACG84X_002737"
     CDS             complement(1323..1934)
                     /locus_tag="ACG84X_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128540.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2047..2304)
                     /locus_tag="ACG84X_002738"
     CDS             complement(2047..2304)
                     /locus_tag="ACG84X_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128541.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2901..3179)
                     /locus_tag="ACG84X_002739"
     CDS             complement(2901..3179)
                     /locus_tag="ACG84X_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128542.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3213..3464)
                     /locus_tag="ACG84X_002740"
     CDS             complement(3213..3464)
                     /locus_tag="ACG84X_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128543.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1195 a          807 c          522 g         1413 t
ORIGIN      
        1 ctgtcccagc ctccttattc cgaataaatg gtgtccaaaa gcttgcatct gccagattat
       61 ctcatttctt atgacaagct aagcaaatta tctccaccaa ataatttatt catatttttg
      121 acttgcgcat actaactaat tcttaaattt tcatacaaaa tttctcaatt tcccttaacg
      181 agtaatattt atgtacggtg attctcacta gtatcccaat cactttttaa gttatcccga
      241 tttcaattct acttcaaaaa tagttgcttt tatgtatgct gttagttgat tagatggtca
      301 tttgttgagc taggtcgttt attttaaaca agttgtttct ttagcttata cctatctcgt
      361 ctaccaaacg caagatggca aacacaaatg catacgcatc tgtatttgcc actttgattc
      421 gtataaagct aacaactatt aactcctctc agctaatagt tgctctcttt tttattcaga
      481 ttcatttttg ctgatcacag cctagtattt caatggtttt gaacactaaa ccaaattgtt
      541 ccattacaac attcactggc tgatgaaatg gattagtaga tttcgattat tcaaagcgat
      601 tttctattgg tggatcgtgt tcccaactaa taagacggat tccaaaccta tcgtacagat
      661 cttctaaacc acttataaat tttgcaccta tttcaggtgt tttattgcgt ggatattcta
      721 ttgttacgcc attaaatgga taccaattag gattaggctc tctttttttc tgtacatctc
      781 ccatagaata gttagcactt tctgggacat aatatattct tcgaccatcc tctaattcat
      841 ctaataagat atttcgtgat cgtctatcac ttgctaaatg tagacgccac gtgcgatacc
      901 atgccatgct acctgcatct gcagaaaatc catcaaataa tgcaacaatt gtatcttcta
      961 tcacaatcct ttccccatct acttcatatt ctaatctaaa atcaaactcc cctcgggtaa
     1021 tttctggtct tggtggctta ggacccaata ttattctact taaaaccgca ttcgttccca
     1081 gatgaaacac agctataaca acaataatga ttaatatttt gtttctattt gataaatttc
     1141 tcattattcg cacatcacct ctacattctc acatattagt tcgtaatact cctttaatat
     1201 caaaatatct actggtcgta ataatattcg ctatgaattc ctactactcg tataagaaag
     1261 gccaaatcat cagcttttac ttgctgatga tttggcttgt ttctatttat cgtaattgtt
     1321 ttctaatcac caaaattgtt aacaatcggt tcagatattt cccagttgat taaggtaatt
     1381 ccgtattgtg tcaaaacttc ttgcgcttct ccgaaattaa gtacagttct tatgtatcca
     1441 ctttctccta atataaagtc tacctctctt ttaaaacctt cctcgagatt tctaagggct
     1501 atatgtggtt ttaatgacat tgattgtaca ttttccccca tataatattg cgcacttcct
     1561 cgactaaaat agattcctag atcgtcccca aaaggtagat cttctctacc actagctaat
     1621 ctacttctcc atcttcgttc tcttttcata gaacctgcgc tgaactcaca cccgttaaac
     1681 tcagctatga cagtatcttc aattatgtta atctgtccat ctagttcgta ttcaatccta
     1741 aatggaaatt ctccataggt gatttccggt tcgggtattt taggtgagat taatgcaaag
     1801 aaaggaaata ttaagcttgg caacatcaaa aaaactcctc ctatgatcac aattcccgat
     1861 gtaatccaaa atataatttg tacaattctc attgatccat tgtattccat tttattcccc
     1921 ctattactat tcatatccgc ctatctatat cgatcttcca atgcagagat aattgcttcc
     1981 ataccttgat tttttactga gttacctatg cgagatatca ttctccacta aggtgcatca
     2041 tattgtctat ctaacatgat taattctcca ataggtgtat actcctccaa aaacaacatt
     2101 taatgcatct ccctcgacaa cataagctac catgtttgct gtatatgtgt ttgagtctaa
     2161 ttcataagca gataaattta ctgtcgctgg attaaatata atcgcattcg tatttatagc
     2221 tactgaattt gctgcttcag caccaccttt tgaatgtccg atcattgtga tttcaatagt
     2281 aggatttacg tggacagccc tcaccgttta ccctgaccat tatagaaatc gcttactttt
     2341 ttgaactacg caacaaagga tacaatgctc ctaacttcac tgtctccatt tttgtccact
     2401 aaggaatata aaaaataggc attaattcat ttaattcggt cacaacacgt taccttttaa
     2461 atcattatac tgtatctcat acattattat caataaacta ttataaaaat gcaaaaaatg
     2521 ctttatcaat ctattttgta attggtcata atatcattga aatcataccc tgtatcgatt
     2581 tttcctatga atctcgtcta tttgtgattg acgaaaaaga ggcaagacag acactggaat
     2641 ggtaatttta cccactattt tgctccaact atttgtaatc gtacccactt ttgaaatacc
     2701 gagatgatca ttttaattga tatgctgatt cccaagcaaa accccaagaa attaaatgct
     2761 ctatcgcatc tagcttcttg ggttttgctt atataaattc caacatttaa attttttatg
     2821 ctgttcggtc tcagaaatgc cgtttttgct tatatcacaa tatcaagatg tcaaattatt
     2881 cgtgttgccg atgactttga ttaatttttt tcaaattgtt tattaagact aatgctgtct
     2941 ttttgcagat accaatgttc gaacttttta acattatcat atgatcctgc aagttttaac
     3001 ttcttaccat tagatgttat caaagttata attaaccttg cctttttccc attaggatct
     3061 tttattttat gaattttctg caggtaatct ctcctaatgg cagctatttt tacctcatca
     3121 gtgctgataa accattgatc atccacatac atactgcctg ttatgttgtg tttttccatt
     3181 tcttccgaga acgaaaagtt taaggctcgt tcttacttcc aaagttgaat gagtccatgg
     3241 attggactta gtgtgagaat tgagaacaac aataagaatc catatcctcc cgcaaacatc
     3301 cctaaggcta tactgtctct ccatccataa gtaggattag aagagaaaag agtcaccgtt
     3361 tgtaataata tgaaaaggaa taatccagca caaacaccaa agataacaac tccaaacatt
     3421 gaatttttat acaatgacca tttatttata ggcttttctt tcattttact tccccctact
     3481 gttctgttca cacggaatga attcaaagtt cataagccct cctctttgaa catatgaata
     3541 cgacttgcta actatacttt aaaaaagctt gttttaagcg gttataggcg agttgtaatc
     3601 tctattcatc tcattagcaa ataacttgcc gaaaagtcta ctgaaattaa agcagatagt
     3661 ggaagaatta tttagccagg atagacacta tttgtgaaac acatgtcttt acttttgaaa
     3721 ttctatgatg aaaagccttg gaatacagta gctcttaatt ggtaatactt tttccattat
     3781 aaataacctc ttttcatttt atatttatcc cctctaaaaa taatatctaa tctaatattt
     3841 taaacttata tttccctcgc tgtgctaata gagcattact aaataaatag aaactagaaa
     3901 aaagcattac gcctgccaga ataaaccaat tatttgt
//
LOCUS       DAZKCH010000144         3872 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000144 DAZKCH010000000
VERSION     DAZKCH010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.150"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..132)
                     /locus_tag="ACG84X_002741"
     CDS             complement(<1..132)
                     /locus_tag="ACG84X_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFP9128544.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     "
     gene            207..485
                     /locus_tag="ACG84X_002742"
                     /pseudo
     CDS             207..485
                     /locus_tag="ACG84X_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
     gene            628..849
                     /locus_tag="ACG84X_002743"
     CDS             628..849
                     /locus_tag="ACG84X_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128545.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            865..1707
                     /locus_tag="ACG84X_002744"
     CDS             865..1707
                     /locus_tag="ACG84X_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128546.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1770..3572
                     /locus_tag="ACG84X_002745"
     CDS             1770..3572
                     /locus_tag="ACG84X_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFP9128547.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3631..>3872)
                     /locus_tag="ACG84X_002746"
     CDS             complement(3631..>3872)
                     /locus_tag="ACG84X_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFP9128548.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1374 a          562 c          774 g         1162 t
ORIGIN      
        1 atgagaaacg ttaatgccac gatcatataa gatttcttga acttcacgat agctaaggtt
       61 ataacgaaga tagtagccca cggctacaat aatcacatcc tgctgaaatt gctttccttt
      121 aaaatgattc atcgtcattc ctcctgctat ctttttctat tattctacct tatttgatag
      181 tagatttaaa actttgcaac agaaccaaag aactcatcaa gctggctaat aagggtcaag
      241 attatgaaca tctagcagat gagattgatg agctgagaga caagcgacag ctccttttag
      301 tagaagatgc ctccctcagt ggcgagaacg agcgaatcaa tgagctgatt gaatttatcc
      361 gcaagaacaa attccgtacc ttagagtacg atgataagct tgtaaggaag ataatccaga
      421 gcgttacagt ctatgaagaa cacttcgtca tatccttcaa atctggcatc gaaatggaaa
      481 tatgaaaacc agaagtaaat agcccatgat tctacagtag agtcgtgggt tttcttttgc
      541 ttgctgatta taataatatt ttaataacta ttgttattat aaaccaaatg atttataata
      601 ttcttagcgt aaacttggag gtgctgtatg actacggcag aaatgattaa agaactgtgt
      661 gagcaaatga atataagtgt ttccgaactt gctagacgta ttggacagac tccacagaat
      721 ttcaataaga aattacaacg agaaacggta accttagatg agttgaaagc gattgctgat
      781 gtgctaggtg tcaagtttgt gcaggctttt atattgcctg atggcaatga aataaagata
      841 ggtaattagg aggtgtaatt tgtattgaaa atcataacaa taaatgatgt tgagtatgct
      901 gtatttgctg ctaatgaagg tacttccaaa ccacaacctc atatcataga aacgaaatct
      961 ggtactattc cagaaggaaa acaactgagt ttattaaaag aatatcttaa gcagaatgat
     1021 atttccccaa taaaaggagc aacaacatat tggtgcattg acaaggttct taagcttgat
     1081 tcaagtaaag aaaaaactat aagtgaaaca atccataaac aaaaatactt atctttaact
     1141 gaagaaaata ttgagaaaca gcataagttt gtaggtgcaa gctctaatta tgggaaagaa
     1201 ggtctaataa tacatgatgt tttgaatgca tttcctcttc ataatgattt aaatactatt
     1261 gcgatgaaga ttgcggtaat tgatgtaaca aattcaacac atctttctca atataagagc
     1321 aggttgtctc tatatgattt ggctaaagta attctggaga ttccaaattt tgatgatcgg
     1381 ttggcaaaag gagatcctca gttgataaat attatcgcaa ggaacattgg tgcagttaat
     1441 atgttctcat ttgcatccaa gtactgtaca tatcataatg tggaagtgtg tgggagagat
     1501 gattactcca tctttgatgg tatcgttaaa aatactcttc cacactatat ccaaggacta
     1561 actacgaata agattgatac gtggcgaaga agttttgatt acgaggcatt taacgaatgt
     1621 gttggaaaac tacttgatga aaataatata catattcctt ttagaagaag aaagttagat
     1681 cacttcttgt ggtatgcgaa taggtagaat ataagaaaaa ggcatcgtaa aagtgattct
     1741 ggataaaatt aatgggggag gaaataatag tgggattatt tgattttcta aagaaaaaac
     1801 aaggaaaggt tagtaaacac gttgattatc aactggcttc tagtctattt cgtactggta
     1861 aagtttttgc tgaaaaattg gaagtggaca tatcaaatgt agatgagttt cgtaaaactt
     1921 ttatcgcttt tgatgtggaa acaactggcc taaattcttc ttcagataga attgtagaga
     1981 ttggtgcggt gctatttaaa gaaggagttc caattcaatc attcggaact cttgtcaatc
     2041 caaaagttag aattgcagcc tcagcttcgg caataaataa tataactaat gaaatgctaa
     2101 actctgctcc aaatgagcag gaagtttacc cccagttggt agaattttta ggagatgcac
     2161 tagatggaaa aatcactatg tgtgcacaca atgcaagttt cgattttgga tttttaagta
     2221 acacattttc tagacttggg tatgatgcta aaattaagta tgttgatact ctgagtctct
     2281 ctagaaaaca tataaaaggc attgtaaatc ataagcaaga gactgtagcg gaatatttcg
     2341 gattaataaa tgacactgcc catagagcgg aatcagatgc agatatatgc ggaaagattt
     2401 tttggggtgt tttagatatt attgaggagt cgttggaaga acaaaaaaag caaatagaaa
     2461 agatgactcc agacataaaa gaacttgaag cttgtgcttt tattcaagat attattgaga
     2521 aaaaaggatg cgacaccagt tggatcaggt atcgaaaaaa cagtaataat tatgtcgatg
     2581 taacttgtct atatacattc ttaaagttta agtttgctaa gaagggaaat tacatcatta
     2641 ttagaaaaga tgctacaaat ggaattgatt tacctataga accttgtact gtaagtgaag
     2701 gcggtacaac aaatgtgcga gtctattttc gtagcccctt tgacttaacg cctctttcaa
     2761 attatatttt cagtgcttat agcgattgtt ataattctat gaatgaatat atgagtgtta
     2821 gtaattacac taaaaaagaa gcagagcaaa gccttagtat gctgaaatct atttcaaaat
     2881 cagcgatgaa agagttatta ttcgatgcaa aaaatcgtgg atatgatgag actgaagtta
     2941 acctaaatat tgaaaaagtg atatctagag aagatgtaat tattaacggg ttgcataatc
     3001 gagtttcatt aaacaagata cgaaatatag ggaattggga gaaaggattt gatgcaggtt
     3061 atccatattg ggaacgtgga gaaactgcta ggaaaaatgg caaagtagat gaagctattg
     3121 cactttttga taaagctcga tataacggct atgatgctcc tgcgctatat gattcttatg
     3181 ctaaagctta tcgaaaaatt aaggattacg ataatgaaat tctcattctt gatgaaggaa
     3241 ttatgcgtaa aacacggcac gatgttggta ctttagaggc tcgtagggat aaggcaatta
     3301 agctattatt tgctaaacaa gaggcagagc ggatagctaa ggaaaaatct gattttctaa
     3361 aagcgaacaa aaaagaggat gcgattagtg agcctagcaa gaagcgtgga agacagatta
     3421 ttcaaatgac tgatgatgga acaataataa aagaattcga tactatagct tctgctgtaa
     3481 aagaagttgg cgttaactca aaaagtatta gggatgctgc aaatggagtt caaaaacatg
     3541 ctggaggata ctactggaaa tacaaagatt agcagataat ctaagataac ctaggatctt
     3601 cttaatagat acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
     3661 ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata tgctttcaaa
     3721 tctactctct agccctttaa cagaacgtga gttgaaattt tgacaaccta atttttctaa
     3781 ggaagaaaaa acagtcccaa ctgtttttct ttgttttcca agtaagctgt ggtctagttt
     3841 ttctgattta tccatgtttt tacgtggcgg aa
//
LOCUS       DAZKCH010000145         3863 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000145 DAZKCH010000000
VERSION     DAZKCH010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.151"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(245..466)
                     /locus_tag="ACG84X_002747"
     CDS             complement(245..466)
                     /locus_tag="ACG84X_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128549.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(564..809)
                     /locus_tag="ACG84X_002748"
     CDS             complement(564..809)
                     /locus_tag="ACG84X_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128550.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1049..1663
                     /locus_tag="ACG84X_002749"
                     /pseudo
     CDS             1049..1663
                     /locus_tag="ACG84X_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2033..3034)
                     /locus_tag="ACG84X_002750"
     CDS             complement(2033..3034)
                     /locus_tag="ACG84X_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HFP9128551.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3193..3459)
                     /locus_tag="ACG84X_002751"
     CDS             complement(3193..3459)
                     /locus_tag="ACG84X_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9128552.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3449..3805)
                     /locus_tag="ACG84X_002752"
     CDS             complement(3449..3805)
                     /locus_tag="ACG84X_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFP9128553.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1222 a          698 c          512 g         1431 t
ORIGIN      
        1 ttactatata cttcttccca gaacttgtcc gtctccttca aattatctct acctctcgag
       61 ttcattgggt ggtttgccca tttattaaac atggaatcac ctttctcata ctcatatatt
      121 tatgtcctat ttcaattata tttatatatg cttaaataaa tttgtatcct gaaatttatt
      181 gtaatatgaa gctgtatttt acatatagta accaaagagt taataaaata aaaagagcga
      241 accattatag atcagctctt ttttcattgc tgtttttaat cttatctaga atcacttcaa
      301 atgtttcaaa ggtatttaca tctaactgac ataaccaaag caagtacttc ttttctttgt
      361 aagtccaatc aatattacgg taagaggaca ttagattatg gtaccttgct ctttgttcaa
      421 ctgaagccaa ttcccagcgt ttttcaaata ttttttcttc ttccattatt gatccctcgc
      481 aagacgctac ctcaaactta aataatgggc agcgaaagtc taattcctta gatctaagta
      541 tagcaaacaa atatgaaaaa aacttagaag gtagtaaaag ttcttccgtc ttttgctttg
      601 cttctattct taatgtgttt cgttatcggt gccctacaaa gattttcatt aattacacac
      661 tcatttattg ttgtgtattt tctgacattt ctctcttgat caattatttt aattccatgg
      721 gcatcctgat agttcatagg agaggagcgg ctatcagaaa tagttgcacc tatctcttga
      781 acttctttta caacttctgg aaaatccatc catcctgctt cagctgtcaa aagtaataat
      841 ctataatatt tatctttcct tttcaatcta agaaatcgtc accccattct ttttcttcta
      901 ttataaacta tttaactttt agaattcaaa aaccgtttgt ctatttagag tttaccctaa
      961 atagacaaaa atataacatt gaaaaattta gagttctaac gtatgattag ggtgtattat
     1021 aaacgttata gaaaagtagg gaataaattt gaaaattgct tatattagag tttcatccat
     1081 cgatcaaaat gaacaacgtc aaattgaaga aatgaaaaag tttggcgctg aaaaaatttt
     1141 tatcgaaaaa caatctggag cgacgattag tcatcggccg attttccagg aagctttaga
     1201 ttttgtcaga gagcaagata tttttattgt agaagccatt gatcgacttg gacgcaatta
     1261 tgacgagatt atcgattcag tgaattatct aaagaagaag aatgtgcgac ttattatcac
     1321 cagtttaccg atcatggctg aagcaattgg aaatcctctc ctagataaat tcatcaaaga
     1381 cttaatcatt taaatctcag ccatgattgc tgaacaagaa cgtactgaat cgaaacgacg
     1441 ccaggcacaa ggaattaaaa tcgctaaagc aaacggcgtc tataaaggtc gtcctaagtt
     1501 atacagtgca gacaccaaag atcctcaacg tcgccttgtc tataggagta tcgttcagga
     1561 tcttgagaat ggggttgcta tctcaaagat tgcaacagac tacaatgtga ctaggcaaac
     1621 aatttaccga ataaaaaaag aaatcgacca actaattgta tgatttcttt tttgaatcac
     1681 gtaattatta attagctttg tcatcaatac agacaatcat tttagattca tctagctaag
     1741 ttgattacat ttatgttaaa aagaatttag ttaacataaa tataattgat gcataaatcg
     1801 tccttattta aaggcattta acattgacaa cttagtataa tgtatcttat gtaaactaat
     1861 aagatttgaa ttttatttta tacacactcg ataatagatc aattttatgg tcccccgcat
     1921 ttacgattgc acaagagaaa cataaagtcg acctattagc atttcttttc aattcaaaca
     1981 ttaaaaaagt ttatacctct gctactaaaa aatgaaatta tctatttaaa atttaaaacg
     2041 gtaaatctga ttcatccaaa ttggaaaatg gatcagcctg tattggagct ttgtatttct
     2101 ccataataac agatatcttt ttttcatttt ttaaaaaata ccttttaaat ttcttatagt
     2161 cctctgaaat caaaatatag cgtgatggat actcatcaaa agaagaatcg tattcttcct
     2221 ttaaaattcc cgatttactt aatttttcta gtacatcaaa tactctatca ctcaagtaac
     2281 tccttaaatt gttatcactt tcccattgaa ctacttttct ataagttgaa ttatcagttg
     2341 aaaagataga attttcatcc ataaacgcat atattagcag caatctttca tcattgtcaa
     2401 attctattgg atcaaaaata tctaagttgt catcaaaatc tttatcagtt ccggtaactt
     2461 ttttgttaat tactgaaggt gtcttgtaag aaatagaatc taaatcaaag cgttttgatt
     2521 ctaaattatt ttgtgctttc tcaattaaat aattcacttt ttttgtgaga aaccttctga
     2581 tattgtcttt gctatatgtt ccataaaaac ccttatcttc taaagagtcc ctgtacttct
     2641 taacttctat atactcttca gccaaaactt gtggaactgg ttcatctaag aaaaaaaccc
     2701 ctacctcgcc tttgctattt ttataaaagt aatcaatttc tgctatagtt cccgatctat
     2761 aattatcaac tggagaaccc aacttatggc caaaaatcgc taataatata tcactatttt
     2821 ctacaatttg tttattaata acactttgcc cagagctatt atttatataa gtaggaatcg
     2881 cattcgtttc ccatcgaatt ggcatcaaaa ttacttttgt attatctgta ttttctatat
     2941 tccatctata tatggtttct tctacttcat tcctctttgc tgctatatca cctggtgatg
     3001 ctataaatac ttttattaga tttatggttt tcatttattg tacctttctc tttatgtctc
     3061 tttaaagtaa tttttgtata aaatttattg acttttacac tataggacaa cttttatcta
     3121 tttagtacaa aaaggcccac taaactaatt gattagttag gagcctatta caggtatatt
     3181 ttcaactcgc ttttaagcaa attctactac cagctttttg cctaatgccc tagcgatatc
     3241 atcaagttta tcgaaagata cgttatcccc tctctcaatt cgagcaatag tagattgagt
     3301 tgtatgtgct ttttgtgcaa gctccgcttg agttaggcct gcttcctccc gtgcatgata
     3361 aagagcaacc gcagtttcga gttttcttcc ttcacggtca tatgcttctg caaaatcttt
     3421 gtctttttgc ttttcttcaa tcaatttttt aatcatcatt tgtgaaccac tcctctctaa
     3481 gttcttttgc atgtttaagt tcacttattg gtgttttctc cgttttttta gtaaatccat
     3541 gggtaatgac ataccttcca ttgaccacat ggaaatagat agctctttgg atgtttgatc
     3601 ctaccttact tcttaattcg tacaaattag tgtctaattt tttcacccat ttcaaccgtt
     3661 gagctactag catcccattc ttttctgttt cttctattgt acgtaaaagc ttcgcactat
     3721 ctttttttgg taatgtttcc aaccattcta aaaattcatc atgaccatta ggtcttttaa
     3781 atgtttcaaa agatattttt tccataccca attatatcat atattgattt tatattatag
     3841 tatataacat aaaaattcga att
//
LOCUS       DAZKCH010000146         3683 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000146 DAZKCH010000000
VERSION     DAZKCH010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.152"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            434..1474
                     /locus_tag="ACG84X_002753"
     CDS             434..1474
                     /locus_tag="ACG84X_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFP9128554.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            2298..2630
                     /gene="traE"
                     /locus_tag="ACG84X_002754"
     CDS             2298..2630
                     /gene="traE"
                     /locus_tag="ACG84X_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFP9128555.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            3249..3590
                     /locus_tag="ACG84X_002755"
     CDS             3249..3590
                     /locus_tag="ACG84X_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFP9128556.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1357 a          483 c          679 g         1164 t
ORIGIN      
        1 tacttattgt attttttagt agtatataat ctattgtttt ctagcctaaa gccttgtctt
       61 ataagaataa tataatatat actactgaaa taaggtagta tatattacta gtaatggtag
      121 tatgttttat atgcataagg tagttcttaa tttatttttt gttttgacac tggtagtact
      181 taattatctt taattttaaa actaaatttt attcatacgt ttttctggta gtatttaatt
      241 ataaataata tttatttaaa gtagttctta atgactttaa aggtagtaca taattcattt
      301 tatttctgat tttaggtagt atttaattaa aaaacagttt taatgcgttt gcatttttta
      361 tttatctttg ctattttcga aaagagtagg taattttaca taaataaaac aacgtgaaag
      421 tagaggatct acaatgactg attttaaatt ttttaaggcg gatagagttt acaacgaatt
      481 attttatcaa tttccaaaag tctttattgt ttctgacgaa tacaaaaaaa tgaaagattc
      541 aactaagatt gcctatatgc ttttaaaagc aagattagag atcgcaatca gcaaacggca
      601 aatcgatgaa gaaggtaatg tttattttac ttatacgaca aatgaactat gtagagtatt
      661 aaactgccaa aaacaaaaag cgatagcaat caaaaaagag ttggaatcct ttggtttatt
      721 attacaaaag cagatgggat ttaacaaaca gttagggaaa aataatccta atagactata
      781 tctagcagaa ttaaaagtct cagaaaatga tatctactta ctcgaaaaat ttgatagaga
      841 gaatagggaa aacgttgata aatcagaggg tatgaaaatc atacccaccc tcgacgaaaa
      901 atcagacgct gaatcccttg gggctcaaga gggtatgaaa atcataccgt gccaaaacgt
      961 tgataaatca gagggtatga aaatcatacc agaacttaat aataatatat tagacactaa
     1021 tagacacaat atagacactg aaaaagaccg cctacaagat caattgttgt tagacaattt
     1081 tgagacaatt atgacaaacg acagcattgc tacgtttgtc cctgaacgag tattaaattt
     1141 gataaaaaca ttttcttcaa gttacagtga agctcaaaaa accgtccaga ctattcataa
     1201 tgcaaagaaa aaagctgaaa tagaaagtga tatttcgata gtttttgaag aactcgatag
     1261 ttattatgtc aatgcagaac aagaattata cacgacactg ttaaaagcct atcaaaaatt
     1321 aaaaaccgaa aaagtcgaaa atatccagaa cctgattttt gtctatgtaa aaaattggtt
     1381 tatcgaaaaa ccaatagctg ctaaagtatc aagtgaaaaa cgtttgaatt atgcaagctc
     1441 cccaagcact attacgaaag actggttaga gtgaaacttt actgacaaag tgattgttgc
     1501 ttcatggagt aacattaaaa ttaaaaattt tttattattc taattatatt acgaatatta
     1561 caaaataata gctattttaa tagaatttat aagttaaaat attatgataa aaatcacaaa
     1621 cgtagccttt tacgtcataa gtgttaaaag aaataattaa tttcaaatat agaaaaggga
     1681 acgtatgttt gcatactcct tttttttgag ttataataat acgcgaagag agataatttc
     1741 attatttaaa caagctaaaa atcttgatat tacttctttt caggcaatac gaatattatt
     1801 cgcttacatt ttttgtataa atttaattgt ctgctatgct tgtgatgaat tgattttcgt
     1861 tttgcacttt tggatgataa atttggacaa ttgaaaatac aaaaaaaaga aaggcggtat
     1921 gaactcggaa ggctggtaac cttcgtcagc gttcatacac ggcattaaga tttggccctt
     1981 aatgcgttaa cctttcagtg ttacggtatt acccgcaatg gatttagtat aacagatatt
     2041 caaaagtgat accacttttt ttggctgtgt taaggttaaa aatacgtgat attacgatga
     2101 atctatgcct aagcataatg ttataaaaat gtccgtgtgg ctctttgccg tatgacgaac
     2161 gctgaaatta gagggaacgc atgtttggat gcgttccctc ttttttgttt gtcatgaacg
     2221 aaaatcaatt ctctattttt gaaaaataac aagaaaaact tgttaaaaat atttaaagaa
     2281 attgggtggt ttattttatg tcatatacag gaattttgag tctcaaagat atttgtcact
     2341 acggtaaacg gtgtaccgct acagagaaaa tcacgaagaa actatcaact ggccaaagta
     2401 aaaccgttgt gcagtgtaag aaatatataa tccagaaaga caaagtctca gaggaaatga
     2461 tttattacat tgggaaacaa aagcaaataa ttttaaaaga tcctatcccc ttaaaagagc
     2521 tatatccaac aatcaaacat gtttatgacc aaaacggtgt actgattggt cgaagaaaaa
     2581 atggagtctt gcgttgtacc gcaaaaggga tggggcgttt gatcggctga attgatcatt
     2641 ctcataactt gtattttatc gtttttcgct tgcttgaaaa tattgtcgag acttctaaag
     2701 gaacttagag tcactagaaa aataaggagt agacttgatc tatcaacaat tcccttcggg
     2761 gagtgacggg gtaggtttta acgattggta acgtaaaaaa ttggtcaatc gagtaaatgc
     2821 gcttgtttgg atagtggtga aatgaatttg tgtaaataat aagcgcagag taaacaagag
     2881 ggaatttaga agttagacaa gttagaatag cgtctagatt aatcatgagc agctactaag
     2941 ggatctagac tttgacgcaa actcatggaa taaggagtag gtcttctcgt aatggggagg
     3001 acgcacaaga aattgtgtcg tgtgctgcag tacatgtaga tacttgcgag gacgttgatt
     3061 attggatcaa tcgagcattt accgctgtct actagggttt ctcgtttcgg acgccataaa
     3121 cgagtcgaaa ttttttatgt atttttaagt aaacgaaaaa cgataaaata tgaacaagtc
     3181 ctgaataaag tgaaaaaatt aatataaagc atagagaaaa tgaaatttac gtaatggagg
     3241 aatgacaaat gaaaaattat gatccgaata tacgattggg cacacatact attaaggttt
     3301 ctttccaacg ttgggattac aaaggatttg tgacgtttag aaggggcgga aattgtaaag
     3361 gattagatgt tttagcatta gacgaggatg atttatacga tcaaacattg actgataatc
     3421 caattggatt cggcttgcta cctgaagatg atgaaggtaa tgaatggttt aaaatgacgc
     3481 ttatgaatga taatggagac gaattatctg ttgaagatac ttggtcatat ttgagtgatt
     3541 atattgtcag ctttgaaatc attgaatttg tagcggataa agaagaataa aaactggagg
     3601 aataaatttt acagataaag gcttagaagg agtcacgacg attaataaaa aggtagtatt
     3661 accttaggca ttgagtaagg aat
//
LOCUS       DAZKCH010000147         3602 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000147 DAZKCH010000000
VERSION     DAZKCH010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.153"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..186
                     /locus_tag="ACG84X_002756"
     CDS             <1..186
                     /locus_tag="ACG84X_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9128557.1"
                     /translation="VEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTV
                     YEGHFVIAFKSGIEMEI"
     gene            329..553
                     /locus_tag="ACG84X_002757"
     CDS             329..553
                     /locus_tag="ACG84X_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128558.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            568..1437
                     /locus_tag="ACG84X_002758"
     CDS             568..1437
                     /locus_tag="ACG84X_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFP9128559.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1418..2152
                     /locus_tag="ACG84X_002759"
     CDS             1418..2152
                     /locus_tag="ACG84X_002759"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9128560.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2185..3093
                     /locus_tag="ACG84X_002760"
     CDS             2185..3093
                     /locus_tag="ACG84X_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFP9128561.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3090..3570
                     /locus_tag="ACG84X_002761"
                     /pseudo
     CDS             3090..3570
                     /locus_tag="ACG84X_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1251 a          521 c          789 g         1041 t
ORIGIN      
        1 gtagaagatg cctccctcag tggcgagaac gagcgaatca atgagctgat tgaatttatc
       61 cgcaagaaca aattccgcac cttagaatat gatgataagc ttgtaaggaa gataatccag
      121 agcgttacag tctatgaagg ccacttcgtc atagccttca aatctggcat cgaaatggaa
      181 atatgaaaac cagaagtaaa tagcccatga ctctacagta gagttgtggg ttttcttttg
      241 cttgctgatt ataataatat tttaataact attgtgttta tcaaccaaat ggtttataat
      301 attcttagcg taaacttgga ggtgctgtat gactacggca gaaatgatta aagaactgtg
      361 tgagcaaatg aatataagtg tttccgaact tgctagacgt attggccaga ctccacagaa
      421 tttcaataaa aaattacaac gagaaacagt aaccttggat gagttgaagg ccattgctga
      481 tgtgctaggt gtcaagtttg tgcaggcatt tattttacca gatggagaag aaataaaaat
      541 atctaacgaa taaaggagga tgtttatatg gtaggtaatg ttattcaaat agtaacagag
      601 aaattatcat ctttgccttt tatagaaggc atcgtattag ggggctcacg tgcaagaggc
      661 acccatacag aaaattctga tatagatatc ggaatctatt acaattcaga ctcatttgac
      721 ctgacagcga ttaatcaaat tgctacagaa ttggatgata aaaatagaaa caaccttgtt
      781 gtgcctcccg gagcgtgggg tgattggatt aatggcggcg gatggttatt tataaatggg
      841 tatcatgttg acttgatttt acgtgatata aaacgggtag aacaaataat caaagatacg
      901 gagcaaggaa ttgttactgc caattatcag accgggcatc cccatggtta tataagtgca
      961 atgtatcgtg gagaattagc gattagtaaa atactatatg ctaagaacga aagcttatgc
     1021 gaattaaaaa agcaggcaga aatttaccct actgctctaa agaaaagctt gatgaacttt
     1081 tttatatttg aagctgaatt ctctttaatg tttgtaaaag caaatgcggg ggtagaggat
     1141 aaatattata ttgcaggcca tgtttttcgt attatttcat gcttaaatca agtactattt
     1201 gcatgtaata atgcttattg cattaacgaa aagaaagcta taaaactgct tgaaactttt
     1261 gaatataaac ctgaaaaata tgccgaaaga gttaatcata tttttgaagt actcggtctt
     1321 tctctttttg aatgctacga tatgaccgag aaactttata aagaagtgaa tgaaattgta
     1381 tcggagataa ataacttttt aaacgaggag agttcagatg aaagaaaaca aatatgatga
     1441 taatatattt tttcaaaaat acagtcaaat gagtcgctcg cagaaaggac tggctggtgc
     1501 gggagaatgg gagactttga aaaagatgct acctgatttt aagggtaagc gtgtgcttga
     1561 tttaggatgc ggctatggat ggcactgtat atatgcgatg gaaaacggtg cttcctctgt
     1621 agtaggtgtt gatatttctc ataaaatgct cgaagtagca aaaggaaaaa cccattttcc
     1681 acagattgaa tatgaatgct gtgccataga agatgtggat ttcccagagg agagctttga
     1741 tgtaatacta agttcgcttg cgtttcatta tgtagcagac tatgagaatt taataaaaaa
     1801 gatatatagg atgctgaagg ctggtggcaa tttagttttt acagttgaac atcctgtttt
     1861 tactgctcat ggaacacaag actggtatta taacgaaaaa ggagaaatac tgcatttccc
     1921 ggtggacaat tattattatg agggcaaacg gacagctatg tttttggaag aaaaggttac
     1981 aaaatatcat agaacactga ccacatatct aaatacactg ctttcaaata gttttataat
     2041 aaatcagatt gtggagccac agccgccaga gaacatgatg gatattccgg ggatggcgga
     2101 tgaaatgcga cgcccaatga tgctgattgt atcggcaaaa aagaagatgt aataatatag
     2161 aaaaaataaa cgaggagtat gtaaatgaga tcagaaaaag aaatgatgga tttagtactt
     2221 tctttagcag aacaggatga acgtattcga attgtgaccc ttgaggggtc acgcgcaaat
     2281 attaatatac ctaaagatga atttcaggat tatgatatta catattttgt aagtgatata
     2341 gaaccgttta tatctaatga tgactggctt aatcaatttg ggaatataat aatgatgcaa
     2401 aagccggagg atatggaatt attcccacct gaagaaaagg gattttccta tcttatgcta
     2461 tttgatgatt acaataaaat tgatcttacc ttattgccct tggaagagtt agataattac
     2521 ctaaagggcg ataaattaat aaaggttcta attgataaag attgtagaat taaaagggac
     2581 atagttccga ctgatataga ttatcatgta agaaagccaa gcgcaaggga gtatgatgat
     2641 tgctgcaatg aattttggaa tgtaacacct tatgttatta aaggattgtg ccgtaaggaa
     2701 attttatttg ctattgatca ttttaatcag attgttcgcc atgagctgct gagaatgata
     2761 tcatggaagg tcggcatcga aacaggcttt aaattaagtg taggcaagaa ctataagttt
     2821 attgaaaggt atatatccga ggatttgtgg gagaaacttt tgtccaccta ccggatggat
     2881 tcctatgaaa acatatggga agcattattt ctatgccatc aattgttcag ggcggtatcc
     2941 ggtgaggtgg cggaaaggct tcattatgcc tatccggagt atgataggaa tataacaaaa
     3001 tataccaggg acatgtataa aaaatacact ggtaaaaccg gctgcctgga tagcacatat
     3061 gccgctgata tagaagagag gcgggaacag tgattacaga aatgaaagca gggcacctga
     3121 aagatatcga taaacccagc gaaccatttg aggtgatagg taagattata ccgaggtatg
     3181 aaaacgagaa ttggaccttt acagaattac tctatgaagc gccatattta aaaagctacc
     3241 aagacgaaga ggatgaagag gatgaggagg cagattgcct tgaatatatt gacaatactg
     3301 ataagataat atatctttta tatagaagat atcgccgtat gtaaggattt cagggggcaa
     3361 ggcataggca gcgcgcttat caatatatct atagaatggg caaagcataa aaacttgcat
     3421 ggactaatgc ttgaaaccca ggacaataac cttatagctt gtaaattcta tcataattgt
     3481 ggtttcaaaa tcggctccgt cgatactatg ttatacgcca actttgaaaa caactttgaa
     3541 aaagctgttt tctggtattt aaggttttag aatgcaagga acagtgaatt ggagttcgtc
     3601 tt
//
LOCUS       DAZKCH010000148         3589 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000148 DAZKCH010000000
VERSION     DAZKCH010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.154"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            467..730
                     /locus_tag="ACG84X_002762"
     CDS             467..730
                     /locus_tag="ACG84X_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFP9128562.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            724..1074
                     /locus_tag="ACG84X_002763"
     CDS             724..1074
                     /locus_tag="ACG84X_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFP9128563.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(1098..1712)
                     /locus_tag="ACG84X_002764"
     CDS             complement(1098..1712)
                     /locus_tag="ACG84X_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9128564.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            2026..2448
                     /locus_tag="ACG84X_002765"
     CDS             2026..2448
                     /locus_tag="ACG84X_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128565.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            2458..2661
                     /locus_tag="ACG84X_002766"
     CDS             2458..2661
                     /locus_tag="ACG84X_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128566.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            2872..3456
                     /locus_tag="ACG84X_002767"
     CDS             2872..3456
                     /locus_tag="ACG84X_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9128567.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         1221 a          523 c          636 g         1209 t
ORIGIN      
        1 agtgtgttta tcgctttttc taagtgcgaa cggaataatt catttaaatc gcctttagtg
       61 actagagttt gcacaatttc tgtagtaaaa tcattcatag ggaagtcctc ttttctgtga
      121 attggttgtc gttaacttta ttctacagaa gggacttcct tttttgtatg gattttttca
      181 tttacacaaa atattttata ctctcattcc attttgtatc aataactatg aaatctttaa
      241 agtatccaga agagattatt tttagatcaa tttttttctt acctgattct aaagattttg
      301 ttttcttaaa catattatga tttcctttcg actattttca tataaatgtt aacatagttt
      361 atggattcat ggaatgttaa tctaatttaa tagaaaagga taattaagta tatacgtttt
      421 ttcttatgta tgttatacta tgtatataca gaaagaggtg tctactatgg aaatgttacc
      481 tataaaaaaa tggggaaata gtaatggcct tagattgcca aagtatatta tggaatatct
      541 tggaattcat acagaagaca aagtgaagat aatacaagaa gaagtaaacg gtcagaagcg
      601 gctaattatc gaagcggcta atatagaaaa tgaattaaca attgaacagt tatttgaaaa
      661 ttacactgat gaaagaaatc atgtgacgat tcaaaattta ggtgaagcag taggtaatga
      721 aaaatggtga gaaaacctag acaaggcgat attctattat tgaatacagc acctcgatct
      781 ggacacgaac agacaggtaa aagaccttat attgttttaa gtcatgatat tattgcggat
      841 tatagtaacg ttgttacagt tgctccaatt tctagtacaa ctagaaacta tccgctatat
      901 gtaaatataa actcagaata tgaaatgaag acaacaggaa aagtattatt agatcaacta
      961 acgacaattg attatgaagc cagagagtgt atttttttgg aaaaagcgca tgatagttta
     1021 gttgaggagt tattgatgaa agttagaaca gtttttcaaa aagtaagcaa ataaaataga
     1081 aacagcagca tgatcaacta ttcgtgattg accatgctgt ctttttttat tctatatacg
     1141 gtttgtctcg taacattgta gtcttttgca atcttagcga tcgcaacacc tttttttaga
     1201 tcctcaacga tgtttttata aacaagacga cgttggggat cttttgcatt ggcactgtat
     1261 agcttaggac gtcctttata aacaccgttc gcttttgcaa tcttaatgcc ttgtgcctga
     1321 cgtcgtttag attcggtacg ttcttgttca gcgatcatgg ccaaaatttg aatgatcaaa
     1381 tctttaatga atttatccag gagaggattg ccaattgctt cggccatgat cggtagactt
     1441 gtgatgatca gctgcacatt tttcttcttc aagtaattga ctgaagcgat gatctcgtcg
     1501 taatttcttc caagtcgatc aatagcttcc acaataaaaa tatcttgatc tcggacgaaa
     1561 tccagtgctt cttgaaaaac aagtcgatga gtaatcgttg cgccagattg tttctcaatg
     1621 aaaattctct ctgcaccgaa ttttttcatt tcttcaatct gccgttgttc attttgatcg
     1681 atggatgaga cacgtatgta tgcaactctc aaaattttta cctactttct gcaactattt
     1741 aaaaaacacc ctaatcatac acgagaaaac cagatttttc aatgtcgcgg tcgtgtctag
     1801 ttagggtata ccttatatag acaaaaacta atgatggagg aaatagtatg tgtcactttt
     1861 ctttttaaat ggcaatattt tttgtaaata aatgtcaatc aagaaaattt aaacgattat
     1921 gacattaaaa atatatttta tgaattttct agtatataac ttgatttatc tgttaagatt
     1981 tattaagaaa acgttttctt atttttgatt tcgaggtgat agacaatgaa aaataagttt
     2041 attttatctt taggtatttt aactattgga attagtgtaa ctggaactac aattcctaca
     2101 tttgctgata gtacaaatga accaactact gtagtagata ataaccaaga attaactcct
     2161 ttagatagga acggaatagc cattggtaac ccaactaacg acttaactgt tactgaaaat
     2221 tatttaatag tttctccatt acttgctcga gcagcttcta aaacgatacg agtgacagga
     2281 acgatgattt ttgataaagt tggttggcct tctagacctc ctcaatcacg gaattggaaa
     2341 gaaaaaagaa atggttattg gtactatgga aaattgtatt tacaaagtta taaatcagct
     2401 ggaaacaatt ggattgcgac ttattcagga accttaacta gaaagtaggg attttttatg
     2461 ccagaatttg tgaacacacc aaatttttat caagatagcg atattctaag taaaattaat
     2521 ttaccgaaag aagaatcagc tttacaagtt cagcgaactt tacaggagac acaaaaaatt
     2581 caaaaatcaa tttctaatct agaagattct gaagaaaaaa gaaaaaaaag agaccaaaaa
     2641 acatatcaaa aagaaaaata atgattttaa aaaaagagtg tctagtcgac attctttttt
     2701 tctaattgaa agtgttcata aaatcaccca tttctggaca ctttcttttt ttgctttatt
     2761 tttcaaaaaa acaattcatt tcatgttcat aaacccataa caatatctat gttcagttaa
     2821 actatatgga taaagttatg ttacaataaa attaatgaag gagtgatttt tttgaaaata
     2881 ggatacgccc gggtatctac tggtttacaa aatttggatt tacaagaaga cagcctaaat
     2941 aaatttggtt gtgaaaaaat ttttactgat catatgagtg gggcaaaaag taatcgacca
     3001 ggattagaaa tggccattga ttttgttcgc tctggcgata cacttgtcgt ttggcgctta
     3061 gatcgtttag gtagaaatat ggaagatttg atttcaatcg tcaatcgact gaatgagcgt
     3121 ggtgtgagtt ttcatagtat tcaagaaaat attacgatgg acaaatcaag ttctacagga
     3181 cagctcatgt ttcatttgtt tgcggcattt gcagaatttg agcgtaattt gatcctggaa
     3241 cgatccgcag caggacgagc agctgctcgt gcaagaggac ggtttggtgg tcgtcctgaa
     3301 aaattgtctg aacaagattt ggaattactg aagactttag tggatagcgg tacacctatt
     3361 aagactattg cggaacggtg gaacgtctca agaaccacca tttatcgtta tttggcaaaa
     3421 atggaggaga aaaatggaaa gacaaattct cattagtttt tgtcatttaa tgctgaaaat
     3481 ttttgccatt tatctagaaa agtgacaata gtatgagaat tttttgtaag tgtctactga
     3541 taacttattc tcaaatgttg taaggatttt attcatttgt taatattaa
//
LOCUS       DAZKCH010000149         3422 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000149 DAZKCH010000000
VERSION     DAZKCH010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.155"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2177)
                     /locus_tag="ACG84X_002768"
     CDS             complement(<1..2177)
                     /locus_tag="ACG84X_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFP9128568.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVL"
     gene            complement(2849..3117)
                     /locus_tag="ACG84X_002769"
                     /pseudo
     CDS             complement(2849..3117)
                     /locus_tag="ACG84X_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          965 a          754 c          539 g         1164 t
ORIGIN      
        1 aggacttcac cactgccttc agcatgttta attagttcaa caccacccgt atcaaggatg
       61 ttttcaatgg ttaacgtcac ttcttctatg gagtattcat ttataaaaac atcatgtacc
      121 gtcgcatcta aaagataccc ttccggtgct tctgtttctc ggacttgata gctacctaca
      181 ggaagcggtt cacttaaaaa ttctccgttt tctgccgtta taccttcttg tatcacttgt
      241 gaatcgcttg ataaaatttc aaattttgct cctgccagcc tttggccatt ctcatcagtt
      301 ttaattactt taatacgccc atcgattttc cttgttctta cagtactcgt attcaatcga
      361 ttgtcactat tcacaagcgt tgcaaagttt aaaatttgat cgccgaccgc atacgcctct
      421 acattgacct taaaagagag ggtaaaactt gtcggaccac caatcgtatt attcgcactg
      481 aaacgaacta ttccattatt gacttcggca tcaatgaaag agggaatatc tgatagaaat
      541 gacacaaatt ccatgccttc ttccaaaaca tcttcaataa caagcgtatt tcttgttcca
      601 gaaaacatcg agacatgcag agtatacgtt agttcatttt cattgagatt gataacattt
      661 ttgtccacac tttttcttaa agagattgcc ggaagattac tttcagggat tctcaagcgg
      721 tagtctcggc tcattacctg attattgtag gtcatactcg ctcgattccg agaaaaccca
      781 tcctcttgtc ttccttcatt gaacaagtcg acatcggtca cttcaagagc atattcaata
      841 aaatacgatt gaccctctgc tagattacca aagtccacaa caagtgtatt cgtttcctta
      901 ttaaaagata ctttgtccac aaattcctcg gaaacataat gagttctaac gtttgcttca
      961 cctggattcg ttacttctgc gatccgaacc ccacctgaaa taggttctct atttccagtg
     1021 gaactccatg tagtcggatt cggtgccaaa gttgttcctt gcggtagtac atcggtaacc
     1081 actacaccgt cttttcgtga tccttcataa tttacctgca aaataaattt attactgttg
     1141 gtcacgtctt gcccgtcaat cagcagattc ccaagatttc cttggctgtc gatttctcta
     1201 gagccatagt ataatttcga aaaaatgggt cttgatgaag gaataggcgt aattgaaaat
     1261 tccgtgtttg ctgctcgctc agcataagta agactcactt gaaagtcatt atttggctca
     1321 gtaccgcctg attgaaagaa agcaacttca aacgtgatac tgaatgtata cgactgagcg
     1381 gcttcattta atccttcata atcaaaggta aatggaaaaa caacgtctgt gccttcttgg
     1441 taaaatgcca gtggctttaa aggtgaatca tcagcgacct ccactctaat gaactcaatt
     1501 aagccaatcg atgctctagg aactcgtacg accatctccc catattcttc aagaatatcg
     1561 ccagcgcctc cttgaatgta tccctttaac gtttgtgtat gcctgctcgg caaagtgggg
     1621 cgctcagcag agatgccgat gtcataattc aagagctcct cttgtctttc aatctgagat
     1681 tcctgcgtta tagatggctc agatgatctg gcttcattaa aagattcact taagctttct
     1741 tctggtatat taaaagattc acttgtgctt tcttctggta cattaaaaga ctcacttgtg
     1801 ctttcttctg gtacactgat ttctattgag accgtatttg attgaatatc accgcttctt
     1861 gcggtcaatt cgtatttacc tgaatgctgg gaagaataag taatcagacg ttcgtaatca
     1921 ttgagttgct tcacttcccc ttcaatcaaa tcctcactct tatcaatgac caatgcattt
     1981 agcaggtctg gtgttcctct gactcgcaac tggaactgct cacccaaagc agcctcctct
     2041 tgatcaactt cgatcgtcag cgaacgctct ggctgttctg ctaaagactc agctagaacc
     2101 gttatgttcc caaattgatt gatcacaata agcataacta gaaacatact taacagttta
     2161 tgaaatttgt tcctcactat tactccccct tataattttg actaaacaac aaggtacccg
     2221 ataattttct aaaaagattc cccaactcaa aatggctgcg ttacctccct cgtattttcg
     2281 gttcaactca agcgttgcaa tgtaagctgt aaacaaagct aatgattgcc gattgtcttc
     2341 tgttgattga ttcgatagct ttgtatgact tttagttgtc cgtgtggctt aaccataatt
     2401 atgatttcac gattcctcct gccagtgcct tgcacaagct ggagcgtaac cctaatagtt
     2461 attttgttaa tgtacttata tacttttata cttttccatt agaaacaatc actaaatcgt
     2521 tgataccaag gtcagactct agaatttcat cagtgagtcc ctgtattggt taaccttcat
     2581 caatcccaaa aaaatatatc aatgcttagc atcaaaatga atatatagtt tagaatactt
     2641 gggattcatc gataactgat cgcttatttg gccatattat ttggcacttg gttcaactaa
     2701 acgcatttag gatgttcctt cattctcgtc atggatgttc tcaaaccgtc attactaata
     2761 aactgtccac cgaatcgatg gttcatttct tgcattttcc acgtccaatt actctttttg
     2821 ctctttattt gggcgtagtt tcactttctt aacttgtatc gtcttccatc aactccttaa
     2881 tcatcttctt agctttattg gctcggtttc cttgtaaaag gtatctacaa atagtgacaa
     2941 tctgtattaa atcttcatca ttttctgtaa tgtcaataat ttctatattc tgtaccatat
     3001 attgcaaagg gtttcactaa gttcataacc gaagcgaatt aaacaacttt tgtatagaat
     3061 aactaccttt tctatttttc cattggtaat tctatctatt aattggttta atccttttgt
     3121 tgtagttgat tccactacca agatgattct ctcgaatttt aaagcttgaa gatgtattgc
     3181 tatttttgct aactggcgta tttgcaacta tttttccctt ctattcttcc ttcattgatt
     3241 cccctctaaa attactatcc ataaaaaatt gcataaatga caatagtatt tatattagtc
     3301 atactgcttt ttaacacagc aaattccaga aaaacattcg ttacatattt gtgaattttt
     3361 ccaaaaaata acatttttat aaaacgacga aaaataaatc actaccagtc aacttctata
     3421 at
//
LOCUS       DAZKCH010000150         3202 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000150 DAZKCH010000000
VERSION     DAZKCH010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.157"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            113..283
                     /locus_tag="ACG84X_002770"
     CDS             113..283
                     /locus_tag="ACG84X_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128569.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            297..914
                     /locus_tag="ACG84X_002771"
     CDS             297..914
                     /locus_tag="ACG84X_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9128570.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVIVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINSLVIELYKYQAESERKKIKERQAQGIEIAKKKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
     gene            914..1852
                     /locus_tag="ACG84X_002772"
                     /pseudo
     CDS             914..1852
                     /locus_tag="ACG84X_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            complement(2545..3192)
                     /locus_tag="ACG84X_002773"
     CDS             complement(2545..3192)
                     /locus_tag="ACG84X_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-7 chloramphenicol O-acetyltransferase"
                     /protein_id="HFP9128571.1"
                     /translation="MTFNIIELENWDRKEYFEHYFNQQTTYSITKEIDITLFKDMIKK
                     KGYEIYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWT
                     ESDKNFISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNS
                     SFLLPIITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDIIHRVDDWI"
BASE COUNT         1172 a          497 c          527 g         1006 t
ORIGIN      
        1 tttctatctt ttataggtca ttagagtata cctatttgtc ctaatatgat tttagcagta
       61 taattgactt ggtgaatagg tcatttaagt tgggcataat aggaggagta aaatgaaaaa
      121 atttatttat cgagttttag aaaatgacga agtggtggct atttttaatg agcaacaata
      181 tgcgcaagat tttatcgctt acgaaaagac aatttctgat aagcaatttg aaattgaaaa
      241 agtagatatt gctgattggt tattgcaacc gagagaattt tagaggttgg ttgaaaatgg
      301 ctaaaattgg ttatgcacgt gtcagtagca aagaacagaa cttagatcgg caattacaag
      361 cgttacaggg cgtttctaag gtcttttcag acaaattaag cggtcaatcg gtcgaacgcc
      421 cacaattaca agctatgctt aactatattc gtgaagggga tattgttatt gttactgaat
      481 tagatcgatt aggacgaaat aataaagaat taacagaatt gatgaatcaa attcaaatta
      541 agggggcaac cctggaagtc ttaaatttac cctcaatgaa tggtattgaa gatgaaaatt
      601 taaggcgttt gattaatagc cttgtcattg aattgtacaa gtatcaagca gaatcagaac
      661 gaaaaaaaat taaggaacgt caggcacaag gaatcgaaat tgctaagaaa aaaggcaaat
      721 tcaaaggtcg tcagcataaa tttaaagaaa atgatccacg tttaaagcat gctttcgatt
      781 tgtttttgaa tggtttatcc gataaagaag ttgaagaaca aactggaatc aatcgccgaa
      841 cgtttagaag gtatcgagca agatataacg tgacagtcga tcaaagaaaa aacaatgaaa
      901 agagggatag ttaatgagta cggttatttt agctgaaaaa ccaagccagg cattagccta
      961 cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat tttgagatca aagacccact
     1021 atttacagat gaaacgttta tcacctttgg ttttgggcat ttagtggaat tagcagaacc
     1081 aggtcattat gacgaaaagt ggcaaaattg gaaacttgaa tctttgccga tttttcctga
     1141 tcgatacgat tttgaagttg caaaagataa gggaaagcag tttaaaattg ttgcagaact
     1201 tctcaaaaag gcaaatacaa ttattgttgc aacagatagc gacagagaag gtgaaaatat
     1261 cgcctggtcg attatccata aagcaaatgc cttttcaaaa gataaaacat ttaaaagact
     1321 atggatcaat agcttagaaa aagatgtaat ccgaagcggt tttcaaaatt tgcaacctgg
     1381 aatgaattac tatccctttt atcaagaagc gcaaacacgc caaattgccg attggttgat
     1441 cggcatgaac gcaagccctt tgtatacgtt aaatttacaa cagaagggcg tacaaggtac
     1501 attttcacta ggacgtgttc aaacgcccac cttatacctt atttttcagc gccaggaagc
     1561 catagagaat tttaaaaaag aacctttttt cgaggtggaa gctagtataa aagtaaacca
     1621 agggtcgttt aagggcgttc taagccccac acagcgtttt aaaacccaag aggagctttt
     1681 agcttttgtt tcttctaaac aagctaaaat aggcaatcaa gaggggataa ttgctgatgt
     1741 tcaaaccaaa gagaagaaaa cgaatagtcc gagtttgttt tctttaagta gtttgcaatc
     1801 aaaagtcaat cagctttata aagcgacagc gagccaaact ttaaaagcta tttctttttt
     1861 aataacttaa aaataaactt aatgtaacag caagcacagt caaggtatac acctttgaca
     1921 aaaaatagca cattctctat cgaaaatttt tgcttatttt ttaaattatt ttgggaaatt
     1981 ttcccaatcc ctttttctaa ctcaaaaaat ataatcactc aaaatttaaa agggcgcact
     2041 tatacatcat tttaaaaaat tgatgtaacg tgctaagttc aaaacaaagg gcgcacttat
     2101 acacgatttt caatcttgta tatttctaac gaaaagcgtg cgccaaaaaa cccccttcgt
     2161 caattttgac agggggcttt ttgatgtaaa aatttctatc gaaatttaaa aattcgcttc
     2221 actcatgtta taaagactta aaataaaata actctttaaa atcttttgct agttgttctt
     2281 caatattttt tattcggtgc atcttccaag taaagtataa cacactagac ttatttacta
     2341 cgtttcataa gtcattaatg cgtgtgctct gcgaggctag tttttgtgca agcacaaaaa
     2401 atggactgaa taaatcagtc cataagttca aaaccaaatt caaaatcaaa accacaagca
     2461 accaaaaaat gtggttgtta tacgttcata aattttatga tcacttacgt gtataaaatt
     2521 aaattcactt tcaaaatcta aaaactaaat ccaatcatct accctatgaa ttatatcttg
     2581 aaattcattc ataaatagtg aagcatggta accatcacat acagaatgat gaagttgcag
     2641 agcaactggt atataaattt tattattctc actataaaat ttacctatcg taataatagg
     2701 caataaaaag ctgctattgt taccaatatt taaattaaat gaactaaaat caatccaagg
     2761 aatcattgaa atcggtatgg tgttttcagg tatcggtttt ttaggaaaca tttcttcttt
     2821 atctttatat tcaagcaagt catttttata attattataa aaagaaatga agtttttatc
     2881 agattcagtc caaatgttag taaatttttc agtttgctta ttaaaaactg tatacaaagg
     2941 atttaactta tcccaataac ctaatttatt ctcactatta attcctgttc taaacacttt
     3001 atttttattt acaacttcca taattgcata aattaaagag ggataaattt catatccttt
     3061 cttttttatc atatctttaa acaaagtaat atcaatttct ttagtaatgc tataagtagt
     3121 ttgctgatta aaatagtgtt caaaatattc ttttctatcc caattttcta attcaataat
     3181 attaaaagtc atatataact tc
//
LOCUS       DAZKCH010000151         3201 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000151 DAZKCH010000000
VERSION     DAZKCH010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.158"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            301..585
                     /locus_tag="ACG84X_002774"
     CDS             301..585
                     /locus_tag="ACG84X_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128572.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="ACG84X_002775"
     CDS             588..1004
                     /locus_tag="ACG84X_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128573.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="ACG84X_002776"
     CDS             complement(1141..1860)
                     /locus_tag="ACG84X_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFP9128574.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2523..2609
                     /locus_tag="ACG84X_002777"
     CDS             2523..2609
                     /locus_tag="ACG84X_002777"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFP9128575.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2912..>3201)
                     /locus_tag="ACG84X_002778"
     CDS             complement(2912..>3201)
                     /locus_tag="ACG84X_002778"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128576.1"
                     /translation="EYRRQRSDFISRKIVRLEKEKMEKFPYEYFQNLEKLEQAIQAIK
                     FDLTDEKLLEYKNMTPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1066 a          597 c          499 g         1039 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtaccc
     2041 ttctgtatcc gttgggagag taaggctcaa ctgcccccta aaaagggttc taaaaaatct
     2101 ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc
     2161 cactttttaa aataaacagg ttcgcgcatg atattaaact gccaatctag ctccctatgg
     2221 tcgctgtaag aaggagtgat cgctacgctc tcacatttta cttgcagcag tcgcctttag
     2281 gctccttcgc caaaaataat tcattaggga ctcctttgtg gcgtcctgag agctcgtcta
     2341 agccgttcta agacaagatt cgataaaaaa ctatgtcctt cgttctaaag cgccttacag
     2401 gcggtcaggg caagccctaa caaccccaag gcaataaaaa acttaggctt atttttgctt
     2461 ttttattgta taattgattg tcgcctatcc gacagtcttg cgactggaag gaggtgtgtt
     2521 tcgtgttcac taactttatt tgctcccttc ttgttgggct tttaagcgct ttgttcagtt
     2581 actggttgaa taaccgaaac aagaagtaaa acttaattaa ggcgactcag cccacaaaaa
     2641 aagccccaga gaatccgacc tctctggggc tttcgtgtgt ttcgtgttca cttatttgca
     2701 atcaaattat aacagaaata aatatttatt tcaaaaatat cctacaaaag tctaaaatcc
     2761 gtaattattt cttatatgca acatttacaa ataaagtcgc tctgagagct cgtatttttc
     2821 gatttaagac gttttattta gtttttggtg tattttcatt ggtccaagct aaaaaactct
     2881 tagaagcgat tttagagcca tttaaaccca cttaattata ttctccatga aattcgctcc
     2941 atgcgtcaaa agctgcgtct gaaattccgc cgtcttcgtt cactagttgc attaattttt
     3001 ccaacgatcg ttttctttcg ggtgtcatat ttttatattc caacaatttt tcgtctgtta
     3061 aatcgaactt gattgcttga attgcttgct ctaatttttc taagttttga aaatattcgt
     3121 aaggaaattt ttccattttt tctttctcca gtctcacaat ttttctagaa ataaaatcac
     3181 ttctttgccg tctatactct c
//
LOCUS       DAZKCH010000152         3173 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000152 DAZKCH010000000
VERSION     DAZKCH010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.159"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            75..503
                     /locus_tag="ACG84X_002779"
     CDS             75..503
                     /locus_tag="ACG84X_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFP9128577.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            490..732
                     /locus_tag="ACG84X_002780"
     CDS             490..732
                     /locus_tag="ACG84X_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128578.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(1032..1247)
                     /locus_tag="ACG84X_002781"
     CDS             complement(1032..1247)
                     /locus_tag="ACG84X_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128579.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            1354..1668
                     /locus_tag="ACG84X_002782"
     CDS             1354..1668
                     /locus_tag="ACG84X_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128580.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1772..2950
                     /locus_tag="ACG84X_002783"
     CDS             1772..2950
                     /locus_tag="ACG84X_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9128581.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
BASE COUNT         1045 a          481 c          637 g         1010 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga aagtatttgg
      481 gtgtcaaata tgaagcaaaa taaacgatat ataccattca taccactaac gacaatcaaa
      541 gccgcagctt ctggtgattc aattgccatg tccatcgttc tgtcaaaata tcaaaattat
      601 atttcacggt tagccatgaa accagtttat gaagaagaaa aaggaatggt tatgtatgta
      661 gatgaatata tgcgtagaca actggaaaca aaattgattg agaagatact tgaatttgat
      721 acaactcgtt aaagtatttt ttccctttcc ttttcattct atggaagttt tttatcgggt
      781 caaaataaag gatttccata ggctgaaaat agcctagcgc tctttgacaa atgaatagca
      841 aatctatcag tacatgtaga ttttgattct ctagttacgc catgacaagg ttagctttta
      901 agcgacaaat tttaatatga gaatcgcgac tacgataatg atacttccgt aaccaaatcg
      961 gcccgccatt actgggggga ggtgagattc ctatgtgctt tggcaaaaca gctgatagat
     1021 cagaaaaact actatttcca tatttcgatt ttggttggca tatttttcat gccaaattct
     1081 gtgattttaa tagcatcggc aagatttaat ttttcttcag ctctctctcc acttttaagt
     1141 ttttttactg tactcaagtt gattcctgtt ccgaatgcta ttgcattagc cgtagatttt
     1201 tcaagaattt ctttaattat ttttatgtct gcaattcctt gtttcatatt aaaaattcct
     1261 cttttctagt ccgttttgat ggagtactgg agtgtttttt tacaatttta aggggtaccg
     1321 tggtggtcgt tttgattttg agagagaagg gtgatggagt tggaagttaa aacaaatgtt
     1381 aattctctgg aaatagagtt ctattcaatt ttacaaaaaa aactggaaga ttacacggaa
     1441 aaattgcttg cagtcagtca tttacctctg gtattaacaa atactgattt aaagcgacta
     1501 tttcagataa gtgatagtac actgaaccgt ttagtaaaac ttggtgagtt tcctccctgt
     1561 tggtacggga ttcgaggaca ctattttcgt gatgatgttt tagaatggat gagaaagagt
     1621 gattcgaatg actatcgaga aaaattgcga ctacttcgat ctttataagt tacattttct
     1681 ttctaagatg cggtacaatg atgacataga tagaaagatt tccaaagggt ttctgcttgt
     1741 tgggttcctt caaaatagga ggaatcaata aatggaaaaa acagatcgat tcaagaagca
     1801 aatcagttct actggtagga tcacatggta ctttcaagca tatcgaacaa caagacgtgg
     1861 ctttaattca aaacgtgagg cgcaactcgc ttatctggaa atggagaaac aacaaaggct
     1921 taagaaaaaa attgttgcaa gcaatgacaa gtttagtgtt gtaggtgagc aatggttcca
     1981 atattaccgt tcgttaaatg aacaaaagga aataacctat gataagcgag aggaacaatt
     2041 aaaaattatt gttcgatgga ttggtgataa aaagttgtct gatttgacac cagagtgcct
     2101 tcaagaattg ctttttacct taaaggaatg tggcgttaat ggaacaaatg ttggctatgc
     2161 caaaaatagt ttacaatcac ttattcaagt tctaaatatg atttttaaat attgtcaaag
     2221 aaagaatttg ataagtgaaa atccaatgaa gtctgtgaga atgccaaaat atcagttaac
     2281 ggtaactgat ttaaaagaag ccataaataa tattgaggac aagtttctta ctgtcgatga
     2341 attgagaact tttttgaatt atggcattgt tcatgaggaa ttaccgatgt ctgtactttt
     2401 ccatgttcta ttttacactg gctgccgagt cagcgaggcg cttgctctac agcctggaga
     2461 tatagatttc aaaagaaatg aaattctgtt ctataagcaa acggcagtta aaggtaagag
     2521 taaggatttt cgaattgaaa ctactaagac agttagttct gctagacgag ttctagtaac
     2581 tcctctagtt atggaaaagc tacaacagtt gattaaggct ttgggtgaga tgaggcaaca
     2641 ttacaggttt attatagaag aaacatattt gtttgtgtat cttgattcta gtaaacgtgg
     2701 tgttccttat cgtcgagagt atgtaaatga tcacgtcaaa cggtgcgtga atcgctcagg
     2761 aattaataag ccatttcata ctcatttagc tcgtcataca atggcaagct tagtagcgga
     2821 acactgtagc tgggaagtct tgaaagatcg cttaggccat actgaccaaa caacttcgaa
     2881 aatttatcgc cacttaacgt caaatgaaaa ggtaaaacct ctgattgctt ttagttcttt
     2941 agagagttaa aaaaacggtg aaagcactgg tattacagga ttcttgaaaa acgatttttt
     3001 aacaaattag tcaatatgta gtcagaggta ataaaaatcc ttttatatca atactttaac
     3061 gacttttcac aagtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa
     3121 cccttggtat tcaagggttc ttttttctta gcatgtaatt tgaacaccct gat
//
LOCUS       DAZKCH010000153         3126 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000153 DAZKCH010000000
VERSION     DAZKCH010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.160"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            72..1040
                     /locus_tag="ACG84X_002784"
     CDS             72..1040
                     /locus_tag="ACG84X_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFP9128582.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            1050..1538
                     /locus_tag="ACG84X_002785"
     CDS             1050..1538
                     /locus_tag="ACG84X_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFP9128583.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            1834..2115
                     /locus_tag="ACG84X_002786"
     CDS             1834..2115
                     /locus_tag="ACG84X_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128584.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            2117..2533
                     /locus_tag="ACG84X_002787"
     CDS             2117..2533
                     /locus_tag="ACG84X_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128585.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
BASE COUNT         1251 a          543 c          475 g          857 t
ORIGIN      
        1 attagggggt tgacccccat tagaaagctc tttataattt tgttaagtag ttaatcttga
       61 aggaggattt tatggcaaat gaaattgtga aataccacca tgaattaaat acgattcctt
      121 tacgcaaatt tacgtcagta gaaatgaatt tattcttctc tataatatct agaatgcgtg
      181 atgtaggcga taaaaaagta caatttacat tcgaacaatt aaaagattta agcaattata
      241 aagcaactgc aaatgttcga ttcatagatg atttagaaac aacgtatgac aaattaatgg
      301 atttacgttt tggtagaaga agtgctgacg gtttgcaacg tgaacgattt gttttattta
      361 atcaatttaa aatcgatgga aaagctgata ttccttttgc tgaaatacaa gtccatgaga
      421 aagccttacc cttacttaat aatcttgaag aatgggttcg atattctctc caacaattca
      481 atgaattaga aagcagttat tccaaaacca tgtttagatt attaaaacaa tacagaacca
      541 aaggaattgc caatttttca aaagaagact ttcatgaatt acttgatatc cctaaaagtt
      601 atagagaaag tgatataaat aaaaaaatta taaagcctat tcgccaagaa ctaaccgcaa
      661 tcttcaaagg tttgacaatc caaaagagat acggaaaagg acggggaaag cctgtcattg
      721 gctatcaatt tacatttaaa cctgagataa aaaaatcaga cgactttaac aaacatgctc
      781 caaccaaaga agaacaaaat aaagctttgg aactagctaa tcaacaggtt caatctgaaa
      841 aagaacctac ttcattacaa gaaaaaatca aagaacaaaa acgaaaatta gaacttttac
      901 aacagttagc agaattagaa agaaaacaaa ataccccaag taagaaaatt aacaaacaaa
      961 tagcagataa caattccgat attaccccag aatttaaaga aaacttacta gataatctcc
     1021 aaaacttatt taaagaataa ggggttttta tgacagataa aactatcaaa gaattagcag
     1081 atattctagg tgtttcaaaa gataaagtga agtatcaact gaggaaatta cctagtaatt
     1141 ttacctacaa aaaaggaaat attacctacc tgaaaaaaga agcagtaaca acaattacaa
     1201 aggttttatc aggtaatgaa tcgggtaact tacctagtga attacccgat tcattaccta
     1261 ccgattacct actcaaggag attgaaacta agaataatca tattgaagaa aaagataggc
     1321 aaattgaaaa acttcaaata gctttagaaa cgcagcaaaa attactcgac cagcaacaac
     1381 aactcaccct acaagccaat caacaaatca aaaaacttca cgaacaactc cagctaacct
     1441 atgcagaaga atcttcagaa aaagaacccc tttctgttac tgaagaaact caaaaaggac
     1501 aaaacaagga gaaaaaatgg tggcaattct ggcaataacc caacaatttt tattcataaa
     1561 aattgttggg ttactttctt tttttgcttt tacaagcata gcgacatgat ctcacgtcgc
     1621 tattttttaa agagcataag gaaacgcggt atcactttct tacgaaaggt gctaggtagg
     1681 ctgtgcctac cacgtttcta agaaaaaaat ttgctatcac tttttcgtca ttgtggatag
     1741 cttatgtata gtgtttcggc aaaaaacagc tatacaaata ctatatttgt atgatataca
     1801 taaattatac acaaatgcga aaggaattct tctatggaca ttttagttcg gaatattgat
     1861 ccaaaagtta tttcagaaat agatagacgt tgccaagaac tcacaacaaa aactggcaaa
     1921 aaatggagcc gtaatgcgta cctaaaagtt ctaatcgaaa acgattttga ccaggcactt
     1981 aggcattaca aaaaagatca attcgattta ttactcgaaa aatttatcga tatacaagca
     2041 aaaaatactg aaacattgaa cgactatgtt catacaaaca accaactcat tgaaacactt
     2101 atcggaggaa tataacatga gaaaaacttc tgttcaaaaa cacgttaccc tttatcccag
     2161 tcacattgac gttttagatt ccatcatcga aaaaaatcca gatatcaata actactcgga
     2221 agccattcgt tttctatgta tgagttatga acctaatact aatacgacaa ctaccagcaa
     2281 ccaagcaaaa ctaaatgcga tgggaaaaga aatttctatt atgtccgaaa tcattgcaga
     2341 atttgctgat ttatatctaa aagatactgg tgttcttatc ggtacaaatt ctaaagtata
     2401 tcaagaagtg aaagaaaaaa ttgaaaatca actcaatccc tcccgacgaa atcaacccaa
     2461 aaatcgtcaa aaagaaacca atcaaacatt cacttctaga aattttgacc caacaaactt
     2521 tctaaaaaga tgaaaaagaa accgaaaatt ttttctattt ctcagtttct tttttagggg
     2581 gcagtcttcc agcaagattt gcaagttacc ggtaacttgc acaaaaaaag aaaaatccgc
     2641 ttgtgcgaat ccttcttttt gcattttggg gcgctgcccc aatctccaaa tatcggttat
     2701 ttaatagcgt ggtaactcaa aaaaatagaa cgtactctga aataaaaaaa gactgctcta
     2761 acgagcagcc aataaaaaat aatgagcgtt tattcttgaa aaagcagcgc gcttatgaag
     2821 cgctgccaaa aatttaccat attttatgaa aaataacaag tttctaaaaa ggaatcggtt
     2881 aagattcaca aagaatcgta aacagacaat agcggaaaat caagcttccg aacgtacctt
     2941 ttagctagac caatgaaaaa tcacaaagtg agcccctgta tcggttgata caagggctac
     3001 ttggcatact cgacattatg tctactagct cgataaataa cgattatgtt cccaaaacaa
     3061 tattttatga actataacaa aaatttgtta tcgcatattg tatattttaa ttataggtgt
     3121 atatca
//
LOCUS       DAZKCH010000154         3122 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000154 DAZKCH010000000
VERSION     DAZKCH010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3122
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.161"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(554..2167)
                     /locus_tag="ACG84X_002788"
     CDS             complement(554..2167)
                     /locus_tag="ACG84X_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9128586.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..>3122)
                     /locus_tag="ACG84X_002789"
     CDS             complement(2308..>3122)
                     /locus_tag="ACG84X_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9128587.1"
                     /translation="YFRLLINESANLYAEFAHKSIELDNPSLLFIDKQQEVQIFSTQK
                     ETQTFIIIQFYFDEQLLAHITGQSFSIDQEITSIITFLKNEQFKIDYLKHSKPAISYD
                     QEINSFFILCQQMSIHLLSLLVTYCLQKIQLSSLPRHYQQELALLTIPSNEKVIPKKK
                     HILYSDELVDPIIRYLEEHLSENFLLEQLAQIFFISPASLKKHFRKVNGKSVISYFKE
                     LKMEKAKRLVLENELTYTEIADILGFHSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1007 a          544 c          546 g         1025 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa aattttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataaaagg gaaggattat ctagttctat
     3061 agatttatgt gcaaattcag catataaatt agcgctttca tttattagta gtcgaaaata
     3121 gg
//
LOCUS       DAZKCH010000155         3113 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000155 DAZKCH010000000
VERSION     DAZKCH010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.162"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            787..>3113
                     /gene="esp"
                     /locus_tag="ACG84X_002790"
     CDS             787..>3113
                     /gene="esp"
                     /locus_tag="ACG84X_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HFP9128588.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         1137 a          461 c          603 g          912 t
ORIGIN      
        1 tatcaagtta tttattcttt ttgatacatg atgaatttat ggattatcaa aaattggatc
       61 agttaattga aagagaaagc tgggaagatt attacgtggg tctaactttt tcagaaaagt
      121 taaacaacta caagttaata gattataagt atttgagtga aagcaattaa ttattcatgt
      181 agagtactag acactttaaa tatggacaat tcaattataa agaaaaagaa tcaataattt
      241 aatgaggctg tgacaaatgt cattttttgt ttcgctaaaa acgagtgaaa aaatgttgat
      301 aactccaatc attcgtttaa gattctagga atcattcaga aatgctgtga aaccgatact
      361 ttataattat aaagaaggtg atttcaaatt ccgaagaagg aatttgaagt caccttttta
      421 cttatgtcac agtctcattc agtaatgcgg gataaggctc cttattccgt tatttgaata
      481 ctctgaagtt taatctaaga aagggtaata ttttgaaaac atgcttcatc gcatagaaat
      541 gaacttaatt tcagaaagaa tacatacata tctttttata tgttttcagc tgctgaatgg
      601 ttaaaaagca caaatatccg aaaaaaacat gaagaaatgt actttttttg ttgtaatgtt
      661 catgaaattc tctaagtaaa ttagttaaca taaggttagt aagattccta ttctgtgaat
      721 aatacgtatc agatttatct tttattctta ctaggaaagt aattattaag ggagttgatt
      781 tgaataatgg ttagcaagaa taataagaga gtatttctag aaaaaacaaa gaaacgagta
      841 ttgaagtaca gtatcaaaaa attaagtgtt ggggttgcat ctgttttgat tggtgttggt
      901 cttgtcttgg gaacaactga actagttaaa gcacaagatg aaatttctcc aagcagccca
      961 cttgaaacag cgataagctc cgtacaagta ggtgacaaag tagcttcggg gaatactttt
     1021 caggagaatc ctggttatac gaaaaattat aacttttcgg atttacaatt tagtcctcaa
     1081 gaactaactg gagacacact aaaaggcaat acaattggat ttgaagttta cggaaaacat
     1141 aatattgcag catcaactaa aaactgggaa atccgtcttc aattagatga acgattagct
     1201 aaatatgtag aaaaaattca ggtcgatcca aagaaaggaa ttggatcttc tagacggacc
     1261 tttgtaagaa ttaatgattc gctgggtaga cctacaaata tttggaaggt caattatatt
     1321 cgtgcaagtg atggattatt tgctggggca gaaacaaccg atacgcaaac cgctcctaat
     1381 ggggtaatta cgtttgaaaa gagcctagat gaaattttta aagagatagg catagacaat
     1441 ctcaagaccg atcgtttaat gtatcgaatc tacttggtaa gtcatcaaga cgatgataaa
     1501 attgtaccgg gtattgatag tacgggctac tttttaacag attcagatga tttctataat
     1561 agcttagatg tatctgaaaa taatcctgac cagtttaaac atggatcagt aagtgcaaaa
     1621 tatgagaaac ctaatactca aacaaaagat ggttcaggat ccacaggtgc taatggagct
     1681 ataatcttag atcataagtt aacgaaaaat tataatttct catattcatc ttccgcaaag
     1741 ggcacgcctt ggtatgctaa ttacaaaatt gatgaacgat tagttccata tgtagcgggt
     1801 atacagatgc acatggttca ggctgacaaa gtaacatatg atgtttcgtt tgaatccgga
     1861 acaaaagtag ctgatttagc aatcgagcga cgggaaggtc atgaaaatta tggcataggt
     1921 tcaataacta ataatgattt aactaaactt atcgattttg ctaatgcaag tccacgtcca
     1981 gtcgttattc gatatgtttt acaattgact aagccattag atgaaatctt agaagatatg
     2041 aaagcaacag cacaagttga agaaaataaa ccatttggtg aagatttcat ctttgattct
     2101 tggttgtcgg atacgaataa aaaattaatc cagaacactt atggaacagg ttattattat
     2161 ttgcaagata ttgatggtga tggaaaccct gacgataaag aagagagcgg agacacgaat
     2221 ccatatatcg ggaaacctga attagaagaa gtatatgatg ttgacacaac agttaagggg
     2281 aaagtattca tccacgagtt agcgggaaca ggtcacaaag cccaacttgt tgataaagaa
     2341 ggtactgtat tagcagaaaa aactatcgct ccaaatgaaa aagatggggc tccaatttca
     2401 gatactgtag aatttgaatt tacgggtgta gattcaagta aattaatcgc gaaagatgaa
     2461 ttaaaaatcc aaatcgtttc tccaggtttt gataaaccag aagaaggttc aaccgttatt
     2521 aaggaatcac caaaagcggt tgataaacaa accgtggtag ttggatttaa accagatgct
     2581 aaagaatcaa ttcggaataa taaaaactta cctgaagatg cagagtattc atggaaaaca
     2641 gagcctgata cttctaacgt tactgatagt acgaaaggta ttgtaactgt taagatcgga
     2701 aatcgaactt tcgacgtgga tgtagagttt gctgtaaaag cttctcaagc tatggaaaat
     2761 gatgcaacat acgtacctat aacaacaact ccagaaacga cagttcaaag tggaaaacct
     2821 acatttgata aaccagatgt tcctttagct aaagatgcct tttcaatttc agatgtctat
     2881 aataagtact tcggtaatgc aagtgttgat gcaaacactg gtattgttac attcactcca
     2941 gctaaaggtg taggagaatc ggagccgatt actggaacaa ttcctattaa aattgtttac
     3001 caagatggtt ctgtaggcac gaccgattta gcagtaactg taagtaaaga tatttatgaa
     3061 aatccaggag aaaacattcc tgcaggctac cacaaagtaa ccttcaccgc agg
//
LOCUS       DAZKCH010000156         3011 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000156 DAZKCH010000000
VERSION     DAZKCH010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.163"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACG84X_002791"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACG84X_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFP9128589.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
     gene            483..1637
                     /locus_tag="ACG84X_002792"
     CDS             483..1637
                     /locus_tag="ACG84X_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C47 family peptidase"
                     /protein_id="HFP9128590.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYVYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1610..2053
                     /locus_tag="ACG84X_002793"
     CDS             1610..2053
                     /locus_tag="ACG84X_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128591.1"
                     /translation="MGQYHYKLVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLG
                     TWQTKDHSERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNL
                     LTLRSNKKQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
BASE COUNT         1038 a          514 c          519 g          940 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcatttc ttgtatagac tgattgtaac atggaacaaa ataaaaaggc
      361 aatacgcctt agttgtcggt cttcgagtta ccaacggtaa ccctcatacc gaacggcatt
      421 catcacccac ctatagagga tgggcgactt ctgcctaatt ctgttaaatt taacacaaag
      481 gcgtgattat tttgaaaccc aaaaagaaaa tttatctagg tctcctcttt tccttgatga
      541 ttggaatttt tagtatagga attacaaata cctatgcttc agaaaattct aatttcaata
      601 tcaactccca accaattgaa gaacaagcaa ttaattttgc gaaaactgat tttgaacact
      661 ccataacttc aattctttta atggaaaata acaccgaaac tgatattaac tatactcttg
      721 gttcgccatt taaaatgctc gatggagaaa atacggcaaa tagttctatt ttctttccag
      781 tattttcaga cgctgataat acgattaaat atgtttatac cgtcaaaaaa aatacaaatg
      841 gagaatattc aggaagtatt tcacaatttt tagcaaaaga acttcaaaat ctagtagata
      901 gtaatataac agatacaacc ttattttttc aagataatag catttattat tccgataatg
      961 gacaaattaa actactttgg aaatcacctt taagtacaga aaaaaatggt gtttcttccc
     1021 ttacagaaaa aaatgatctt atatccgtaa atataaaaaa taaaattaaa aatttttcta
     1081 aaaaacaaaa ttttcctgcg gttaaacgtg taaaaagtgt ctcctccgga gataacttta
     1141 ttatgattaa ttggcgtata gcagaaaccc aaacaagttt tccgtggtgc gctgcttacg
     1201 tagaagctgc tatcttatgt aacaaaacag atgtacgtgc tacttcagct agagccatta
     1261 tgcattatac ctatcctaat ttaaacaaca gtcaaattga atcaaaaagt cttaatcaag
     1321 atcaaataat aaaatatgca aattactgtg gtgtttatcc taaaaaaata gcacgaatac
     1381 taaacctttc agaggtccaa acacaactaa gaaaaggaaa tgccatttat atgggaactg
     1441 ctggttatgg aaattatagt aacagccgtc atgcacttgc attatttggg tgggtcaatc
     1501 aaggtggtta tcaaacttac tatgtgtgga atccttggta taactaccca actgtaataa
     1561 gtgcaaatgc aggaccagtt acaattcctg tacctggagg tggttttact tgggacaata
     1621 ccattacaaa ttggtaaata aactcattgc tttagttatg ggtctagtgt tagttctttt
     1681 cttaactagt tgttcaaaaa aacaagaaat acaaaagact gatctgattc cttttctagg
     1741 aacttggcaa actaaagatc attcagaacg tctagtaatc actaatttaa atacttcaaa
     1801 aaatatagaa caatatacca tcttagtaaa agagaacaat cataaaattc aaatcattga
     1861 taaaaattta aatataaatg aacaagtttt catttacaaa gcaacaaata atttactaac
     1921 actgcgctcg aataaaaaac aattagatta cacttttagt ttggattctc caaaaaagct
     1981 cgtatttatt ttgacaacga atgatgggac agaagggaca gctaaaccaa ttgaattttt
     2041 taaagctgat tgatgaatag ttgtttgata ttacaaaaca ataatttcac cgaaggtgaa
     2101 acaagcgaaa ctttacaaaa agtggctagc atttgctagc cttttttgta ttgtggagcg
     2161 tgggttttga gggggattca agggggagct tgcgcccctt tgacaagcgg ttatttgcac
     2221 caaatacgta ggtatttggc tagcaaatat agagcttgcc aagcccttta gtgtgttttg
     2281 tagaaaggga ccttatagtc actttcacat tacaaacgat acgtcctatg gacgtatcaa
     2341 aagggtggga cttatgagca aattaaagca aaatttggct agcaatcctt ctaaaaaata
     2401 cacctattga tcagagtcaa aataaatcag ttttcgagtg agcgaatcca aatttgcaac
     2461 tctgaagctt tgcaaatgag tgtgccggct tccgtaaaag tctaggtaac attagtcgat
     2521 atatacatag ggctctaatt tgcgttttaa ggcgttttaa acgttctggt atgtaattat
     2581 accaaagcga ctttaaaacg ccttaaaacg aattttagag gttctgtaga acgttttagg
     2641 gttgttaggg cttgccctga ccgcctgtaa ggcgctttaa aaacaagata agggatttta
     2701 tctagacttg tcttaaaacg ccgtagatga gcgctcagag cttctaaaag gactccttac
     2761 gaactgtttt taagcaaagg agcctttagg cgactgcgca gtttaatgtg agagcgtagc
     2821 gatcacacct ttaaagcgac cgtagggagc agattcccag tttaggaaat ttcgcgaacc
     2881 tgtttggaga aaaaaagtag gaaaatttta ggcgggaaat tttgcccccc tcttttataa
     2941 tctcttttat aacctctttt taaacctctt taccgtcggc tgtatcctta ctctcccaag
     3001 gtgtgcagaa t
//
LOCUS       DAZKCH010000157         2929 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000157 DAZKCH010000000
VERSION     DAZKCH010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.164"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..981
                     /locus_tag="ACG84X_002794"
     CDS             85..981
                     /locus_tag="ACG84X_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFP9128592.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIVHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
     gene            1073..1288
                     /locus_tag="ACG84X_002795"
     CDS             1073..1288
                     /locus_tag="ACG84X_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFP9128593.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
     gene            1306..1578
                     /locus_tag="ACG84X_002796"
     CDS             1306..1578
                     /locus_tag="ACG84X_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFP9128594.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILTKEKVA"
     gene            1580..2443
                     /locus_tag="ACG84X_002797"
     CDS             1580..2443
                     /locus_tag="ACG84X_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFP9128595.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAISEETQGNVVIIDNDTFKQQHPNFDELVKLYEKDVVKYVTPYSNRMTEAI
                     ISRLRDKGYNLVIEGTGRTTDVPIQTATMLQAKDYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQPPTP
                     PIPKTPKLPGI"
BASE COUNT         1160 a          464 c          510 g          795 t
ORIGIN      
        1 gagggctttt atatattaat cacaaatcac ttatcacaaa tcacaagtga ttaatcacaa
       61 atcacttgtg atttgtgatt cttaatgata caatattact atacaaaaaa agaatggggc
      121 gtagttatgg agaaggaaaa actaaaaata cttgaagaat taagacgtat tttaaacaat
      181 aaaaatgaag caattattat cttgaataat tactttaaag gtggtgttgg aaagtccaaa
      241 ttatcgacta tgtttgctta cttgacagac aaattgaatt taaaagtttt aatgatcgat
      301 aaggacttac aggcaacatt gacaaaagac ttagcaaaaa cttttgaggt agaattgcca
      361 cgtgtcaatt tttatgaagg cttgaaaaat ggaaacttgg cttcttctat tgttcatttg
      421 actgataatt tagacttgat ccctggcacg tttgatttga tgttactgcc aaaattaact
      481 cgctcatgga cttttgaaaa tgaaagtaga ttgcttgcta ctcttttagc acctttaaaa
      541 agtgactatg atctcattat tattgatact gtaccaacgc caagcgttta tacaaataat
      601 gcaatcgtgg cgagtgatta cgttatgatc cctttacaag cagaagaaga aagtacaaac
      661 aacattcaaa actatatttc ctatttgatt gatttacaag aacaatttaa ccctggacta
      721 gatatgatcg gttttgttcc ttatttagtt gatacggaca gcgcaacgat aaaatcaaac
      781 ctggaagaac tgtacaagca acataaagaa gataacttgg ttttccaaaa tattatcaag
      841 cgaagtaata aagtaagtac ctggtctaaa aatggaatta cagaacacaa aggctatgac
      901 aaaaaagttt tatccatgta tgagaacgta ttttttgaaa tgcttgagcg aattattcaa
      961 ttagaaaacg aaaaagaata gaatcacaaa tcacaagtga ttaatcacaa atcacttgtg
     1021 atttgtgatt gttgatgata aaataagaat aagaagaaat agaaagaagt gagtgattgt
     1081 gggaaattta ggcgcacaaa aagcaaaacg aaatgataca ccaatcagtg caaaaaaaga
     1141 tataatggga gataagacgg ttcgtgttcg tgctgactta caccatatta taaaaattga
     1201 aacagcaaaa aatggcggaa acgtaaaaga agttatggat caagccttag aagaatatat
     1261 acggaaatat ttacctgata aactttaaaa aggagtgaaa atgaaatggc agttacgtat
     1321 gaaaaaacat ttgaaataga gatcattaac gaattatcgg caagcgttta taatcgagta
     1381 ttaaactatg ttttgaacca tgaactagat actaaaaata ctcgtttact agaagtgaat
     1441 cttttaaatc aattagaagt ggcacaagaa gttgatttat ttcaacaacc atttgaagaa
     1501 ttacaagcta ttcatgagta ttggcggtca atgaatcaat attcaaaaca aattttgaca
     1561 aaagagaaag tggcttaaca tggcgaatat tactgacttc accgaaaagc aatttgaaga
     1621 tcgtttagaa aagaatgttg aacgactaac taaaaataga ctagcggttg aatcgccaac
     1681 cgctttttta cttggtgggc aaccaggatc aggtaaaact agtttgcgat cggcaatttc
     1741 cgaagagaca caaggaaatg ttgttatcat tgataatgat acgttcaaac aacagcaccc
     1801 taattttgat gaactagtga aactttatga aaaagacgta gtaaaatacg ttacccctta
     1861 ttctaatcgc atgacagaag cgatcataag ccgtttgaga gataaagggt ataatttagt
     1921 gattgaaggt acaggacgaa caacagacgt tcctattcaa accgcaacaa tgcttcaagc
     1981 caaagattat gaaacaaaaa tgtatgtcat ggcagtacct aaaatcaact catatttagg
     2041 aacaattgaa cggtatgaaa ctatgtatgc agatgatcca atgacagcca gggcaacacc
     2101 aaaacaagcg catgatattg ttgtcaaaaa cttaccgacc aatttagaaa cccttcataa
     2161 aacgggctta tttagcgata taaggcttta caatagagaa ggagtgaaac tctattcaag
     2221 cttagaaacg ccttccatta gtccgaaaga gaccttagaa agagaattaa atcgtaaagt
     2281 atcagggaaa gaaattcaac cgactttgga gagaatagag caaaaaatgg ttcaaaatca
     2341 acaccaagaa acccctgaat ttaaagcaat tcaacaaaaa atggaaagct tgcagccacc
     2401 tacaccacca atacccaaaa cacctaaact tccagggatt taaaccttaa aaaagtaaaa
     2461 gagtagttac caaaaaacgg taactactct ttttttataa aaacatttcc tcatttttta
     2521 aaagctgatc gagaaataaa gcacacaact gtattctttc ttttttcagt tggtacattt
     2581 tgcagtctgt aacgtgccat ttactgtttg ttaccttaac atatccagtc gaaaacacaa
     2641 gggtatataa acgagcaagc tcgcccttgt gttttctttg tgtctatgtt gcgttctcgt
     2701 cacagcaaac gacacgaaca cactggcgaa aatgaaccaa caaaacgaaa aaagaaagga
     2761 gcgtacactg taatttattt ctagctttta aaacatgagg aaaacagctt cacttcctca
     2821 aacgcctaac aaaaatggtt gtcaaaaaac taaaaatcaa aaaaagaaaa gaggaaaaga
     2881 aaatggaaaa aacaaaaaaa ttacaattag aagattttac agaaaatgg
//
LOCUS       DAZKCH010000158         2866 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000158 DAZKCH010000000
VERSION     DAZKCH010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.165"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..897
                     /locus_tag="ACG84X_002798"
     CDS             82..897
                     /locus_tag="ACG84X_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128596.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            1023..1280
                     /locus_tag="ACG84X_002799"
     CDS             1023..1280
                     /locus_tag="ACG84X_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128597.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1532..2104)
                     /locus_tag="ACG84X_002800"
     CDS             complement(1532..2104)
                     /locus_tag="ACG84X_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9128598.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2120..2725)
                     /gene="fic"
                     /locus_tag="ACG84X_002801"
     CDS             complement(2120..2725)
                     /gene="fic"
                     /locus_tag="ACG84X_002801"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFP9128599.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          929 a          524 c          449 g          964 t
ORIGIN      
        1 ataggataat atattaaggt gctggactac aagtaaaaaa tactgtatga tcatgacaga
       61 ttcaagaaag gagcaataag attggttaag atagcaggac tttctaaagg tggaaaaacc
      121 gtttcacaac tttataaaca aaactacaga gactggagac agttcagaaa aaacattaag
      181 gattcttact ttattctacc aacagaactt gaaaaatatt taccgaataa caaagctatt
      241 aatttatatc tgtattactg ttttaaggca aagaatgaag gcggggattc ctggcattcg
      301 gtcaatacca tagcagagtc tctaggagtg acaactaaaa ctataaacac ctggaataaa
      361 accttagttg atttaggtat gattgcacgt atagacgata accatctcag taaatcgaca
      421 attttacttc ctctctctag ttactataaa ttagcccttg atagttcttt aaaggatgtt
      481 accgagagca ctgtccatga aattgatggc aacttggttg cagtttatca tttgtttgaa
      541 tggagaaaaa atgaggctga tgaaaattat aacgttcctt ataacacact ctgttgtgtt
      601 tttaaaagaa aaacacaaaa agatactatc tataaattta tcttggtcca agatgagaaa
      661 ataagtaatt tcgaattaag cactccttct agtaagattt atgacgatgc atatagattt
      721 gaatgtcaag atctagaagc cctcctttcc gcaaataatc taaacaatat agaacatgaa
      781 aactttgttg taaacactag atttaattta gtttctgaaa aggactcaga tttgttagat
      841 ttgctgatag agcttactaa aaatctagat aagaaagaaa acattactgt actataacta
      901 gcatcggtcc atcattaagt ttggactatt agaacacttg ctattacaga aaaaggtatg
      961 ctagccacgc ttactattta ttggtatcaa acaagtatct taatttgaaa ggaagatgat
     1021 ttatggctaa tttatatata gagaacaaag gagacttgaa tgccattatt actttaatcg
     1081 tagttatggt aaaatcaata ggtaatatca caataggaat gctgtttatt atattagcag
     1141 cagtgctgat ttttatgata gttatttggt tcttaaatga aagatctaaa gacaatcaac
     1201 accgtaggga tatggagata aaatcaatag agtcaataga ttatttatcg ataataacac
     1261 taaaaaagcc acgttcctaa acgtgactta cgctgaacga tatgtgttgt ttggtagacg
     1321 aacaaatcgt tcattataaa tatatgatgg tatcctaata tagtaagcgt ggctagcata
     1381 cctttaatta ctttaccttt tacagttacc atacacattt tttgagcaga aatcaagtaa
     1441 ataaaaaaat attatatttc acaacatgct aatagactca tatctagaac gcattaagta
     1501 tttacctgtc tggttcgctg agacttcttt tttaactttc ttcaattttc ttctttattc
     1561 taaaaagcgt actgcgactg aaaccggtta tagcttcaac ttccttatac gatttacctg
     1621 aagtaagcag ttcatatgcg tgcctcttct tcggtgtgat tgttgctttc ggacgtcctt
     1681 ctctgaaatt aggattattc tttcttgcaa acatttttcc ttcttgggta cgttccacaa
     1741 tcatatcacg ttccatttct gctacactca acaacgtccg tgtcaccatt cgccccatgg
     1801 acgtattttc aatcgttcct agattcaaaa ccttgatcgt tacgttatca tcgagtaaag
     1861 gttcaatgat ctctaatgct tctctcgtgt tacgagcaaa tcgatcaagc ttcgtaacaa
     1921 ctatttcatc tccaggcttc agaccagcca acagctgatt gaattttggc cgatcccgtt
     1981 ttgtacccgt aaatttttct gaaaaaatat tcttcttctc tacgccgttc tcaagcaact
     2041 gttgaatttg ttcttttgta ctttgagaag cggttgagac acgtgcatat ccatatttcg
     2101 tcatttggtc cacctacttt tacaaatcat ctatcgtata ctcagaatac ccttcataga
     2161 aatagctgac atcgattcct ttcatatata actcgcgatc gtcaatttta tcagtcagag
     2221 cattggaaat tagatagcgt atttccaaat cgtttatggg acttcgctcc attgcagaaa
     2281 gatagtctgc tttatcgatt aagttccaat ctacaacttt ttgcaattct tcctttaaaa
     2341 tgagatccag ccaaattcta gtacttcggc catttccttc tcgaaatggg tgagcgatat
     2401 tcatctccac atatttcttg ataatctctt caaaagaagt ttgtggcatc tgatcaatat
     2461 gctgtaacga atgttctaaa tacataactg gtgcaaatcg aaaatttcct tttgcaatat
     2521 tgaccgatcg gatttttccg gcaaaatcgt aaatatccga aaatagaaat tcatgaattt
     2581 cagataaacc tttaaatgta ccaacttcga tttcatttat ttttccacaa tcgtacaatt
     2641 ctttcgcttt ttgtttactg agtttttctt caaccttagc caactcaact tgattggtta
     2701 atcccaattt attctctaaa atcatgcgaa atctccttaa ctttatgaca taagtttatg
     2761 aaacactctc aaccccatta tatcgcgatt ttgtttatgt gtcaaaaact attaagtttc
     2821 tgacccccga tagatttttc aagtgtctct attttgcaca gtctag
//
LOCUS       DAZKCH010000159         2865 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000159 DAZKCH010000000
VERSION     DAZKCH010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.166"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1757
                     /locus_tag="ACG84X_002802"
     CDS             <1..1757
                     /locus_tag="ACG84X_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128600.1"
                     /translation="NLLKKDNSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSV
                     NFMRNAQEIYTTGDLSFHLSRIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAV
                     VFYGISNNLILSYVLYIWLLNICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVD
                     IYYRSAIAEAIALTIIPAVLYYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSAL
                     IACMIIVRLFLSKQIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFK
                     TDLQLEALSISDSIIQALNNDITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVS
                     TWVCVTNLFPWFLFQKTPISLLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLII
                     GATVVFLLVTSIAAKENYAKVIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKE
                     RPHLEKHEVKVGESWEKGKYKAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVV
                     NDSYKKHGLVNVDVNAGENKIEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKL
                     KDSRYVTKKEINKKNENK"
     gene            1744..>2865
                     /locus_tag="ACG84X_002803"
     CDS             1744..>2865
                     /locus_tag="ACG84X_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HFP9128601.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLF"
BASE COUNT          972 a          420 c          468 g         1005 t
ORIGIN      
        1 aaaacttatt aaaaaaagac aattctagta tactgaaaat agaattaaaa aaggagaaca
       61 acaaatctat gaaaataagt aaaaaagcat ttcttttagt agttcttatc ttacttagta
      121 ctttatattc agtaaatttt atgagaaatg ctcaagaaat ttatacaaca ggtgatttat
      181 cttttcatct ttcacgaatc aaagggttat cttctatttt tgaagggcca atcaactata
      241 caacatttaa caattatgga gatggactga actattttta tccttttctt acaataattc
      301 ctgcagtcgt tttttatgga atttcaaata acttaatatt aagttatgtt ctatatattt
      361 ggttattaaa tatttgtacg attctgatta gtttttatta tggagaaaag ttttttaaaa
      421 agatagatgc tgctttttta tttagttgtt tatatacttt tgcaacttat cgaacagttg
      481 atatctatta tcgatccgca attgcagaag caatcgctct tacgattatc ccagctgttt
      541 tatattatgc ttatggattg atattcaata gagaaaaaaa agtcatcgct ttatctgtca
      601 gtataagtct acttgtgtat actcatgtct taactacact attgtgtagt gcattgattg
      661 cttgtatgat tatagttcgt ttgtttttaa gcaagcaaat aaaaaacgat ataaaatttg
      721 tggtcgtgaa tttagtaaag gctgtttttt tgacttgtgc attaactagc tatttttggt
      781 atcctatgtt gcagcagatg aattatcaag aaatacacag tcccttcaaa acagatttgc
      841 agctagaagc actttctatt tcagatagta tcattcaagc gttaaataac gatattacaa
      901 catacactat ggggttatta ggattggttg cgttgatttt tcctttattc atactgaaag
      961 aaatggagaa aaaagaaaaa atcatctatg ttggcgtagt ttctacatgg gtatgcgtaa
     1021 ctaatttatt tccatggttt ttgtttcaaa aaacaccgat aagcttactc cagtttcctt
     1081 ggcgtatctt aggtatccaa atcttttttt cttcaatgat cataacgctt gtttttatga
     1141 aaaagactat gaataaaaaa tattcatggt taatcattgg cgctactgtg gtgtttctac
     1201 tcgtcacgtc tatagcagca aaagaaaatt acgcaaaagt tatccaatca aaacacggtc
     1261 atattgttat caatgaagaa acactcccac gttatacaac atcagatatg ggaggattat
     1321 acgattacgc cccaacagaa gcgataaaag aaaggcctca cttagaaaaa catgaagtaa
     1381 aagtaggaga atcgtgggaa aaagggaagt ataaagctgc agataataac attacttaca
     1441 cagtggcaag caacaaaaag caaaaagtga cagtaccagt atatgcttat ttaggtacac
     1501 aggtaaaagt aaacggtaaa gtcgtaaatg actcttataa aaaacatggc ttagtgaatg
     1561 tggatgtaaa tgctggagaa aataagatag aaattacaac aaaatatact ccaactgctc
     1621 tcatggcttt atggatcagt attctgactt attgtttagt ggtgtattca agttttaaac
     1681 gatttgcacc taataagttg aaagattctc gatatgtgac taaaaaggag ataaacaaga
     1741 agaatgaaaa taaataaaaa agtagtaata ttgagtggat taattatagt tagtagtata
     1801 tattctttca tctttttcaa aaatacacag agtatttata ccactggaga tctttctttt
     1861 cacttatctc gaatcaaggg gttatcgact atttttacca gtccgattaa ttatgagaca
     1921 ttcaattata ctggatatgg tgtaaattat ttttatccct ttctgacttt ttttccagct
     1981 gtaatgttat attggatgac aaaaaatttg attgtaagct atattattta cgtttggtta
     2041 ttgaacttgt gtacaacact cgtagcttat cattatggcg agcggttttt aaaacaaaaa
     2101 aaagcggcat ttttatttag ttgtctctat attttctctg cttatcggac agtagacatc
     2161 tactatcgtt ccgcaattgc cgaagctatc gcaataacac ttgttatccc tgtattattt
     2221 tatgcttatc aaatcatctc tggaaaagaa gaaaagtatc cgtctgtaaa gctagcattg
     2281 agtatgagtt tgctagtgta cagccatgta ctatcaacat taatgagtac agcattaatt
     2341 atcattttta tttttattcg tttggtttct aaaggtttca agaatgcaga ttttattgct
     2401 atatttaaaa aattatttag tgcggcagga atgacattgg ttctgacgag tgctttttgg
     2461 tatccgatgt ttgaacaaat gctctaccaa aaaatcaaca aacctagcgt gacaaattta
     2521 tatgctcatg catctaatgt gttcgatagt ctgactgaag ctatgaacaa cgacttaact
     2581 acttactcaa tgggactagt tggtctgtta tctttatgta ttcccctgat tttatttaaa
     2641 aaattaacaa acatagaaaa aaagatttat tatggtacgt gtttgacttg gctagctaca
     2701 actagtttgg tgccatggta tcttctgcaa aatacgccag ccaaattgtt acaatttcct
     2761 tggcggatct taagcttgca aataatattc tcttctctga tattaacgat gatatttttc
     2821 aaaaatagaa gatacaataa gacaagagaa ctattttatt tattt
//
LOCUS       DAZKCH010000160         2846 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000160 DAZKCH010000000
VERSION     DAZKCH010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.167"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..855
                     /locus_tag="ACG84X_002804"
     CDS             <1..855
                     /locus_tag="ACG84X_002804"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFP9128602.1"
                     /translation="IIHMHMSYRGSFSRKYVLNKWFRLLNIPVIIHLHGSEFKKWYDS
                     VSVKKQNQIRLLLRESDSTIVLGEKWKKIIKEIEPNCKTVVVENSIVVPEYTIKWNSK
                     MCRFLFMGVLIKRKGVHDLVEAVKNIAEQYPEKKFIFEIAGAGDEEISLKELIEEYNL
                     QSYFEFTGWVVGEKKEECYRRSNVMILPSYNEGLPISILEAISYGMPVIATDVGDISS
                     AVRDGENGYLFQPGDVSALTSAILKINDKDKYVKFSRCSKDLAITKFNDGNFFDRILN
                     LYQKGSKE"
     gene            1423..2484
                     /locus_tag="ACG84X_002805"
     CDS             1423..2484
                     /locus_tag="ACG84X_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9128603.1"
                     /translation="MNSSDLISVIIPVYNVEKYVGSCLESVCNQTYKNLDIIIVDDGS
                     KDSSNKICEDYALKDSRIRIIHKNNAGLGLARNTGLEHVKGKYVAFIDSDDFVAANYI
                     EAMLNGIKRSNADTCYAGYYEYYDDNNIISKPARYDSTIFTNNAIIEKVLLGMIGTEP
                     SYKVDFILPMSVWHALYSSEIIQQHNIKFPSERDYISEDIIFHISYLQHSKITSFIKD
                     CIYYYRCNNNNSLTHNFRDNEFDCNIELVKKIEGDLSYILENEIFVNKTRRLLLGRCR
                     TCIQKAVRYASFNKEFDLNSYLSKILMNDELIACIHSYPYKQNPIKQRIFNYFLLNQS
                     IIGVKTLAYLSGMGRNRRF"
BASE COUNT         1063 a          302 c          547 g          934 t
ORIGIN      
        1 attattcata tgcacatgtc gtacagaggg agttttagta ggaaatatgt gctgaataag
       61 tggtttagat tattaaatat tcctgtaatc atccatcttc atggatcgga atttaaaaaa
      121 tggtatgata gtgtttctgt aaaaaaacaa aatcagattc gcttgctgtt aagagagtct
      181 gattccacga ttgtacttgg agaaaaatgg aagaagataa ttaaagaaat tgagccaaat
      241 tgtaaaactg ttgttgtaga aaattctatt gtagttccag aatataccat aaagtggaat
      301 tcaaaaatgt gccgatttct gtttatggga gttttgataa agcgaaaagg tgtacacgat
      361 ttggtagaag cagttaaaaa cattgcagaa caatatccag aaaaaaagtt tatttttgag
      421 attgctggag caggtgatga agaaatatcg ctcaaagaat tgatagaaga atataatttg
      481 caatcgtatt ttgaatttac aggttgggtt gtgggagaaa aaaaggagga gtgctataga
      541 agatcaaatg tgatgatttt accgtcctat aacgagggat tgcctatatc tattctagag
      601 gcgatttctt atggaatgcc tgtaattgct acagatgtag gagatatttc ttcagcagta
      661 cgtgatggag aaaatggata tttgtttcaa cctggtgacg tatcagcgtt gacatctgca
      721 atactaaaaa tcaatgataa agataaatac gtaaaatttt cacgttgttc gaaggatttg
      781 gcaataacga aatttaacga tggaaatttc tttgatagaa ttttaaatct gtatcaaaaa
      841 gggagcaagg agtgatgaca aggaaaataa aaaatgtttc gattatgtaa tgaacttatt
      901 aagtgaataa aatagagaga aaaaatattg aaatagacga tgtaaatttt tatccgtgta
      961 agaattcaaa tgaatagtag tgttttagtg cttgtaatag agcaagagta caagcacggt
     1021 acattatata aaaacattaa tgatatttct ataaataaat agattttgta ttctggatga
     1081 tgaagaggaa gatattatct gataacttac cctaaacttt gcagggggtg gttataagtt
     1141 gtgtatatgt ggcagtaatg aatgagtgaa ataatcatat taagaaataa aattgcaata
     1201 ttgtgtaata caaaagtata ttttcattat tccaagggaa agcatactta cgaggatcat
     1261 attattgatt taataaataa tttaaaggaa ataatttttc tagaagaaga tagtatgtca
     1321 ttcacatcat caagatcaga gtctattttt ttcagagaat ttaagaaaat cgttgatgcc
     1381 gtcattgact aattgagaaa acgtgagtga aaggatagaa ggatgaattc gagtgatcta
     1441 attagtgtaa tcatacctgt atataatgtt gaaaagtatg taggaagttg tttggaatca
     1501 gtgtgtaatc aaacatataa gaacctagat attataattg tggatgatgg atctaaggat
     1561 tcatctaata aaatatgtga agactatgca ttaaaggatt caaggattcg tattattcat
     1621 aaaaataatg ctggcttggg attggcaaga aatacaggac ttgaacatgt aaaaggaaaa
     1681 tatgttgctt ttattgattc tgatgatttt gttgcagcta attatattga agcaatgtta
     1741 aatggtataa aaaggagtaa tgcagacaca tgttatgctg gatattatga atattatgat
     1801 gataataata ttatttcaaa gccagcaaga tatgatagta cgatatttac aaataacgct
     1861 ataattgaaa aagtgttgct tggaatgatt ggcactgagc cgagttataa agtcgatttt
     1921 atattgccaa tgtcagtttg gcatgcgctg tattcatctg agataattca acagcacaat
     1981 atcaagtttc cgtcagaaag ggattatata tctgaagata tcatattcca tatttcatat
     2041 ttgcaacatt caaaaataac aagttttatt aaagattgta tctattatta tagatgtaat
     2101 aataataatt cattgacaca taattttaga gataatgagt tcgattgtaa tattgaatta
     2161 gttaaaaaaa ttgaaggcga tttaagctat atattagaaa atgagatatt tgtaaacaaa
     2221 acaaggagac ttttgttggg acgctgtcgt acttgtattc aaaaggcagt tagatatgct
     2281 agttttaata aagaatttga tttaaactcc tatttgtcta agatacttat gaacgatgag
     2341 ttgattgcct gtattcactc atacccatat aaacaaaatc caattaaaca acgaatattt
     2401 aactattttt tactaaacca atccattatt ggggttaaaa cattagcata tttaagcgga
     2461 atgggtagaa ataggagatt ttaatcataa aaaactgtac tatagtgaat ttttggagat
     2521 ttatattcca gttatatatt aatgattgtg atacttgtac tattgtaaaa attcgttagg
     2581 tttaaataac tggaaatatc ggaaaatggg cattatacat cacggacatc ccttcttttg
     2641 gaaaaaatgt tacgattttt ataagtaata ttgtatccgg tggaatcaac gatgaagata
     2701 acatatccat cgttgtagat tcagtagcat tgaatgatgc tcttgttgca agaaatccga
     2761 ataaaattgt taagtataaa ttgaattaat aggagatatg aatggaaatt agcagtaaag
     2821 aatatttaaa agcggttctt cgtatg
//
LOCUS       DAZKCH010000161         2809 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000161 DAZKCH010000000
VERSION     DAZKCH010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.168"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            14..1141
                     /locus_tag="ACG84X_002806"
     CDS             14..1141
                     /locus_tag="ACG84X_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9128604.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1359..2501)
                     /locus_tag="ACG84X_002807"
     CDS             complement(1359..2501)
                     /locus_tag="ACG84X_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9128605.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2506..2691)
                     /locus_tag="ACG84X_002808"
     CDS             complement(2506..2691)
                     /locus_tag="ACG84X_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFP9128606.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
BASE COUNT          928 a          515 c          447 g          919 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa ccaccggtgg caaaccggtg gcaaatccat gtaaacatgg
     1201 tttatttttt acactgtttt caaacaaacc cttgctattt cttcggttcg tcctcgtcca
     1261 ttttcgatac cgacagctag cttataaccc aaggtatatc aacataaaaa aataaaaata
     1321 ggctatgaca gcagcgtgac agcaaaaaag atggaaagtt aaatatcaaa cctcgtaatt
     1381 tcatttgcga gtgcttgatt tgtttctgga tataagtgtc catatttgtc caaagtagtt
     1441 ttaatagagg catgacctag acgcttagat attgcataga tatttttatt atgttcaatt
     1501 aaaaaggcaa catgcgagtg tcttaatcca tgcatatgaa ttggttttac tcctgcaatt
     1561 tcagctagtt tttttattct gcttaaaata gttcttggag atggcggtaa tccatcaaaa
     1621 gaaaaaacca attctatatt tttcccaatt gattgttgag tttttttcca tgtttttaaa
     1681 tcttcaacgg tttgtctgtc taacgaaatt atccgaatac ttgatgtatt ttttgtttca
     1741 gcaaattcat aatcttgtct tgtacggatg taaattgact tatttacgct acatctgcca
     1801 tttattaagt caaagtcttt ccattgtaac gctaagagct cctcactcct tacacctgta
     1861 acaaaaataa aacgcatcaa acgtttataa aattcttcat aaaaatcccc gtgataaaca
     1921 ctattatata ctttcttaaa ttcatcaact gtccaaaatt ctacttgagg acgctgagtt
     1981 tttattttac ctatagtatc tacaggattt tcttcaataa tttcaagtac aattgccctt
     2041 ttaaaaacta ctctcaactt attgaatatc tgtttaatat aatttggtga taatggttgc
     2101 tcaatgccct tttttacaac atggattttc gataaaaact gttgaaattc ctgtatatga
     2161 attggtcgaa tctttacaac ctgcatttct ccaaaaaaat ccaatgcacg ttgtaaaata
     2221 tgatctgttt tcatatatgt tttttctaca gttcccaact tataccaagg aaaaaaatac
     2281 tctcgataaa aatcatgaaa cgttattcct tgcagataaa ttccttgtga atcagaaaaa
     2341 ctttgtttta actcttcgag tccccttcta gcttctcctt gagttttgaa gcctcttctg
     2401 gtcacttgaa ttctttttcc aaagcgatct tgtcctaaag ttgcagaaaa aaaccaagtg
     2461 cctctttttc tgtctttata aacattcgca attttcctca ttttactatt cctcccaaga
     2521 aatatggaga acttcttcta aaattgaaat aggaattctt tttatttttg aattacgata
     2581 aaaaaagtat cctttctcaa ctaaaagttc tttacattcc ttgaagattt tattagcata
     2641 gtactgagaa aaacctagat taatcaaatc ttttcgagta gctgttttca ttatagcacc
     2701 ttccttactt tttttcattt atttctatca gctgcttttg tcaaaagcac ataggaattt
     2761 cacctctccc caagtttacg gcgagcctta cggaagtatc attatccca
//
LOCUS       DAZKCH010000162         2796 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000162 DAZKCH010000000
VERSION     DAZKCH010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.169"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            182..418
                     /locus_tag="ACG84X_002809"
     CDS             182..418
                     /locus_tag="ACG84X_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HFP9128607.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            437..652
                     /locus_tag="ACG84X_002810"
     CDS             437..652
                     /locus_tag="ACG84X_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFP9128608.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(1355..2107)
                     /locus_tag="ACG84X_002811"
     CDS             complement(1355..2107)
                     /locus_tag="ACG84X_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9128609.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(2122..>2796)
                     /locus_tag="ACG84X_002812"
     CDS             complement(2122..>2796)
                     /locus_tag="ACG84X_002812"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9128610.1"
                     /translation="REQYEQQLKRKELVYLKKYTDSLEKDQEKFARFRHDYKNLLLSL
                     KEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKNEYLKSLLIAKLYQANNN
                     KICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQDRELSLAIYRDDKQIEI
                     SISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKKNPNMFVNYQNDPYQFTT
                     QVILLF"
BASE COUNT          901 a          442 c          443 g         1010 t
ORIGIN      
        1 ctcataattc cacaaaaact ttgaaaacag ttcttgaaca ctaacttttt cattcctgaa
       61 tcaaatttat tttggaaatt ttactattca agaataaact tgataagttt caggaagatt
      121 tttactgtta atcaaatacg tatgttacag tagcaccgta aaaaatatta tttaaagaag
      181 cgtgtttaaa catgcaaaat gtaaaggaac taagtattgt ggaaatgcac aaactgttgg
      241 tggaggcaat aatgcttggg gaaaattggg gcaagttgta ggtggactta ccacaggggc
      301 agtaggtggt gcaggtttag gaacagcaat ttgcggacca gcttgcggtg ttgttggagg
      361 gttatatgga gctgtcgctg gaggtgctgc agctggctgg gatgctcgaa aaaaataaaa
      421 aaggagaata agtagtatgc atattaaaaa cacaaaaaca acatttatat tatcttcaga
      481 agagttgaaa aatattcaag gtgggagtgc cgtgggagtt ttaggcacta ctttttctgg
      541 ggcaacagca ggagtaaaac tttgttcagc cggaggacct tatgcaatag ctgcttgtgg
      601 tgtaggtgga gctttattag gtgctggatt cagcatgtgg accggtgcgt aaacaattaa
      661 aaaatatcaa acctcaagat tggtttgtgt cgattacgaa cataggtatg ttctttatct
      721 tttcaaaagt ttggaatgga cagaactttt tactaaagct tcttgtgcta gtttttataa
      781 ttatattaaa tttttatctt ttattaaagt cagataaaaa ttctttggaa atgtaatggt
      841 agagatattt ttacaaaagg acttgcagcg ctgtagttgg tgctgcagga ggacctattt
      901 cggccgttac aggaggtatt ggtaatgtac ttgtcggatg tgcattaaag cctgttcctg
      961 caagttaaat ttataaaaac aggaaagtaa ttatctcaaa tcctatcaag tacaatcata
     1021 ggattgcact tgacaggaca aattttttaa ctaaaaaatg aaaaacactt tctaaaaatt
     1081 agtagaattt gccaaatctt tcgcatcttc caccatacat ttaattttaa ttccccttta
     1141 tggtacttaa taaaaacaag aaaagaacta ttcatttggc ccttttttgg ttccagacca
     1201 tagaaatatt cctccagtaa ctaatattgc tgttatgcac gtaactaata acagctataa
     1261 aaattggtac aactttaata ggattcagaa aaatttgcac tagtgaagga atctatttta
     1321 ttagaaaaat gcaatctccc taaagaaaaa accactaaac agtgctttct ttcaacttct
     1381 ccttaatttt ttgtgctttc cctaaagtaa agtttctggc caactctgaa tcaaaatata
     1441 gtgaacgttt tttaaaatct atttctttaa cgttaaagat atttactaaa cacgctcgac
     1501 taattcttgt taacatagga tatttctttt caagctcact aattcttcca taaaattcgt
     1561 actgcccatc tttagtacac aatgataatc tatgtggtaa ttttgaagct tctacaaaat
     1621 aaatgtcatt tatatcaaaa gtaaatgttt gagaacctat ggaaaaaaca aatgcttgat
     1681 tcgtaacctg ttttgttgca tctatccttt cttgcgctaa taacaataac tcaacaatct
     1741 cgtttcgata ctcatctagt gtttgatctt ttgttacaaa tcctaacgtt tcaactcttc
     1801 tttttattgt tacgggtaac atctcatcat gagtagttgt aaaaatgatt tttgcttgaa
     1861 catcatattt tctgattact tctgctaatt ctataccgtt aacttcatga tttaaatcaa
     1921 tatctaagaa atatattcct tgctttggtc ggaattgttt gaggtatttt ttaacttcta
     1981 acggactttg tgttttcaat actatcttaa atactttatc gtgaaaaaga atgaaattat
     2041 caataattcg ttctaactga tttaattgta taatttgatc ttcacataat attattggat
     2101 aactcataaa tcctccttcc ctcaaaacaa caaaataact tgagtagtaa attgatacgg
     2161 atcgttttga tagttcacaa acatattggg attcttttta ttgatttcct ctatactaga
     2221 taaacctaac ccttgatgtc ccttttttgt tgttattcct tttttcatta gagtatctat
     2281 agagagtagt atctctctac aactattcga tatcgaaatt tctatctgtt tatcatctcg
     2341 gtaaatagct agagacagtt ctctatcttg actctctata gatgcttcaa ttgcattatc
     2401 gagaataatt ccaagcaccc taatacagtc aaatattgga acaggaactt caataatagt
     2461 acttggacat tcgaatttac aacaaatctt attgttattt gcttggtata gcttcgctat
     2521 caacaaactt ttcaaatatt cattttttat attttttaaa taacgatatt caaacttatt
     2581 ggttagataa gaattagaat agatctctaa ttcttttatt tctttttcca atatcgaatc
     2641 atggttttga ttagcgattt cttttaaact cagcaataaa tttttatagt catgtctaaa
     2701 tctggcaaat ttttcttgat ctttttccag tgaatcagta tattttttta gataaaccaa
     2761 ttcttttctt ttcaattgct gttcatattg ttctcg
//
LOCUS       DAZKCH010000163         2767 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000163 DAZKCH010000000
VERSION     DAZKCH010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.170"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            223..1626
                     /locus_tag="ACG84X_002813"
     CDS             223..1626
                     /locus_tag="ACG84X_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFP9128611.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            1975..2607
                     /locus_tag="ACG84X_002814"
     CDS             1975..2607
                     /locus_tag="ACG84X_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFP9128612.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
BASE COUNT         1049 a          391 c          525 g          802 t
ORIGIN      
        1 caaattacat tagacaaatt gaaaatgtta gattatttat ttcatcctag ttttagccaa
       61 ccctataatt ttattttaaa ggcagtaaca ggattaaaca ttgaaacata atcgttacta
      121 aatgaaatca agaaatatac tgtattactc aattcattga aaatatttat cataattttt
      181 aatagaaaac actattaaag agaaaaaaga gaggtaaatc aaatgaaaaa atctttaaaa
      241 cttgcatcag cagttatatt aatgtcccaa ctccttatag caacaccttt ccatgtgttg
      301 gcaagcgaaa attcaacata caaaattgca aaagaaagaa ccgagacgac tgaaatgagt
      361 aattccgatg taacagcaga gagtagtgaa cttttgacaa cttcatcaag tgaaagtagt
      421 acgacttcaa atgccgagtc ttcaacaact tcatcaagtg aaagtagtac gacttcaaat
      481 gccgagtctt caacaacttc gtcaagtgaa agtagtacga tttcaagtac cgaatcttca
      541 acaacttcaa gtagtacaag tgaaataact tcttcgaaag tgacaaaacc aaaccatata
      601 gaatcttcaa aaaaggaagc gccaaaaacg gaaggacaaa caaaaacttt ttcgacacca
      661 cagcaaatag aatcaacaga atctttccaa tcacaaccaa tactatctgg taatgaagaa
      721 attcattttg acaaaaatga atctgtagaa aattttatta tgaaaattgg tgagtctgcg
      781 agaaaaattg gtcagaaata tgatttatat gcttctgtta tgattgcaca agcgatctta
      841 gaatctgcca gtggtcaaag ccagttagct caggcaccga attacaattt atttgggata
      901 aaaggaactt ataatggaaa ctttgtcatt atggtaacaa acgaagattt gggtaatgga
      961 acgctttata cgacccaatc aaaatttaga gtgtatgaaa actatgagga aagctttgaa
     1021 gattatgcca aattattaac taagggaatt agtggaaata aagattttta tgcaggagca
     1081 ttaaaagcta atagtaaaac atatcgagaa gcaactaaat tccttacagg acggtatgca
     1141 acagatacac aatactattt gaagctaaat gaattaatta aaacctacga tttaaccaac
     1201 tatgataaag aagttaaagg tccacaaatg agtaagactg gataccaagt gcctattcat
     1261 aattattcaa taaccagttt gtttggaaat cgtggaaatg aatttcaccg aggacttgat
     1321 atggcagcta cacagggtga gccgattcat gcagttaaag ctggtaaggt tgttaaagca
     1381 gagtttcact actcttgggg aaattacgtg gtgatacaac acgaagatgg atcaaccgcg
     1441 ttatatgctc accagcaaca atacctagta aaaactggag ataatgtttt gcaaggacaa
     1501 ataattggct atgtaggaag tactgggaat agtactggcc cacaccttca tttggaaatt
     1561 tgcaaagata gtagtctttc tcagagcatg ttagttgatc cgaaaacctt attattcgga
     1621 gactaaaaaa ggtaatcaat ctgacaaagt aacaagaaaa tggttggatt cttagacctt
     1681 tgatcaggat attgagactg gaattgatat ctcgattacg atgggtttga caaataaaac
     1741 aagtccatta tcgaatatcg agtgtattat tgccgtcttt atgctcatat tttgagcagg
     1801 tttcactaga tgaaaacaat ttatctatct tgaggatttc gtgtacgtat cgttcagtct
     1861 tgtattgtaa attagtcata aaatcagact aagaaaaatt ggaaatattt ttttctgatt
     1921 tattaaaagt taattgaaat tatatggtac ttctttcttg ggagggtagg tgcagtgaag
     1981 gaaagatatg gtcaccttac tgttgttgag gagattactc ataatggata taaaaaatat
     2041 cgttgcctat gtgactgtgg gaatgaaacg attgtatatc gatcaaactt actatcaggt
     2101 agaaccaaaa gttgtggatg tggaaattat aaaaataggc ataaatataa aaatttgaca
     2161 aataaaactt ttggtaagtt agttgcaatc aagccaacta aactgcgaag tgaaggaact
     2221 gttgtttggg aatgtcaatg tctgtgtggg agaaaaaagt tagtatcggc aaagcgactt
     2281 ctaaaaggtg atgtaaaaag ctgtggatgt ttgaaatcaa aaaagcatca cattgaaaat
     2341 aaaaaattcg gattacttac tgcaaagtat cctttggaca ataactgttc atggaaaaca
     2401 aaatgggttt gtcattgtga gtgtggcagt atgtgtgaga taagttatag taacttattt
     2461 tttggacata ctcaaagttg tggatgttta aaaaggcaag aaacaaggac atgtgttgaa
     2521 gggacagtaa tagagtgtct aacgtcaaaa ttaccgaaaa ataatacaag tggtgttaag
     2581 ggagtttatc gttctaaaga gaaatagatt gcgtatataa ctttaaaaaa aaagaggtac
     2641 tatttaggat cgtatgattc tattaagagt gcagctcaag ctagaaaaga tgctgaaaat
     2701 aaattgtttc aacctttgat tgacaaatat cgaggtaatc attaattatt gtggataata
     2761 attaaca
//
LOCUS       DAZKCH010000164         2761 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000164 DAZKCH010000000
VERSION     DAZKCH010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.171"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..562
                     /locus_tag="ACG84X_002815"
     CDS             <1..562
                     /locus_tag="ACG84X_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFP9128613.1"
                     /translation="KFEKKKYVLQVFHPVVTELENIEKQILALINSMEQQSQPIICIL
                     PNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTILKECKFMIGNSSSGIIEAASFK
                     IPVINLGTRQNGREQSKNIINANLNENEIETALNKIQDPQFIKSLKNVKNIYGDGNSS
                     RRITKTLNQILNDGEDIKWIQKQIAY"
     gene            535..1212
                     /locus_tag="ACG84X_002816"
     CDS             535..1212
                     /locus_tag="ACG84X_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFP9128614.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            1163..2344
                     /locus_tag="ACG84X_002817"
     CDS             1163..2344
                     /locus_tag="ACG84X_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFP9128615.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            2357..>2761
                     /locus_tag="ACG84X_002818"
     CDS             2357..>2761
                     /locus_tag="ACG84X_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9128616.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHN"
BASE COUNT         1042 a          355 c          529 g          835 t
ORIGIN      
        1 aaaatttgaa aagaaaaaat acgttttgca agtatttcat ccagttgtaa ccgaactaga
       61 aaatatagaa aaacaaattt tagctttgat caattcaatg gaacaacaat ctcaaccaat
      121 tatttgcatt ttacctaata gtgatgctgg tagcgaaatt atcagaaaaa tgtaccagaa
      181 atatttaaaa acggatatta tttatattac gaatttagag ccggaggaat acctgactat
      241 attaaaagag tgcaaattta tgatcggaaa ttcttcttct gggataattg aagctgcatc
      301 attcaaaata ccagtaataa atttaggaac cagacaaaat ggacgagaac aatctaaaaa
      361 tattataaat gcaaatctaa atgaaaatga aattgaaact gctttgaata aaatacaaga
      421 tcctcagttt ataaaaagct tgaaaaatgt taagaacatc tacggtgacg gcaacagttc
      481 tagaagaata acaaaaacat tgaatcaaat attgaatgat ggggaagata ttaagtggat
      541 tcaaaaacaa atagcttatt aaaatatact agtgatccat acattattat tggggctggc
      601 ggacacgcaa aagtcattat tgaaacctta agattagaaa ataagttaat atatggattt
      661 tttgatgata agcaaaataa aatgcaagat ctgaaatatc ttgggaaaat aaacgaattg
      721 aatagctggg cggatagcaa aaaaaaaatc tataaattta ttgtagctat tggtgactgt
      781 gtagtaagaa aaaagattat aaaaaaattg aatatgccaa gtgagcaata tggaatagct
      841 gttcatccaa gtgctatagt ggcaaaagaa atttcaattg gttatggaac tgttattttt
      901 gcgaatgctg taattaaccc agatgctgta attggagagc atgctataat aaacacaggt
      961 agcattgttg agcatgattg tagaattaat aactatgttc atttatctcc aggtgtatgc
     1021 ttagcgggtg gagtacatgt aggtgtagga actcaaatag gaattggttc tcaatgtatc
     1081 cagatgaaga aaattggatc ttggtgtatg ataggcgcag ggagcactat tgttaaggat
     1141 attccctcac attccttagc ttatggcaat ccagctaaaa ttaagaaaga aggaattaat
     1201 tttgaattct agaattttat tatcaagtcc tcatatggga ggaacagaag aaaaatatgt
     1261 tgctaaggct tttaaagata attggatagc gccattaggt gaaaatgtgg ataaatttga
     1321 agaaagtatt acaaaatata ctggttctaa gggcggagct tctgcgttaa gttcaggtac
     1381 agctgccata catcttgcct taagactgct taatgttgga aaaaacgata ttgtctttgc
     1441 tccttcattt acttttatag ctacagtaaa tcctatttta tatcaagggg ctgtaccagt
     1501 gttcattgac tcagaaccta atacatggaa tatgagccct gttgcactag agagcgcatt
     1561 agaagaagct gaaagaaaca accaattacc taaggcaatc atcgtagtga atttatatgg
     1621 tcaaatggct gattatgaac gaattttagc tattgcaaac caatttaatg ttccagtgat
     1681 agaagatgca gcggaatcgt taggttctac ttataaggga atttcgtcag gcttatttgg
     1741 gacaattggg atctattcat ttaacggtaa taagatcatc acaacctcag gtggaggagc
     1801 tctagtgtct agtgataaaa aatatgttga gcattcaaga tttttagcaa cacaagcaag
     1861 agatcaagca ccgtattatc aacatagcga aataggttat aattaccgtc taagcaatat
     1921 ttctgccggt atcggacgtg gacaaatgga agtattgaat gatagagtag ctaaacgaag
     1981 agaaattttc aatcgatata aggaagcttt ttctggaatt gatagaattg aaatgatgcc
     2041 agaagtggat ggcatggtgc caaatcgttg gttgtctact ttaacgatca atgattataa
     2101 ttctattgat caagtagtta acgtaataaa taaactaaat gaaaaaaaca ttgaaacaag
     2161 agctttgtgg aaaccactac atttgcaacc agtatttcaa ggggtaaaaa tgtattacca
     2221 tgataataat cttagtgtgt cagaaaagtt atttaatagc ggcttatgct taccttctgg
     2281 aagtaatatg acagatagtg aacaagaatt tgttattgat gagtttaaaa aaatattcaa
     2341 gtaggtgtga tattttatga acataggaat tattggttta ggttccatgg ggaaaagaag
     2401 acttagactc attcaagaac actttaatga tattttacta tgtggtgttg atactaatga
     2461 ggcgagacga aaggaagttg aaaaggaatt tggaatacca acttataata gtctaacaga
     2521 ggcaaaaaat ttgtttgaaa taaattcagt ttttgtttgt acatccccta taacccatga
     2581 atttattata aaagaggctt taaatttaga ttgtaatatc tttacggaaa tcaatttatt
     2641 aaatgaatat tatgatgaaa taatcgaagt agctaaaaag aaagatagat tactttatct
     2701 atcttctaca tttttgaaga gaaaagaaat tcaatatatt aagtctaaag tgacgcataa
     2761 t
//
LOCUS       DAZKCH010000165         2736 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000165 DAZKCH010000000
VERSION     DAZKCH010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.172"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            77..523
                     /locus_tag="ACG84X_002819"
     CDS             77..523
                     /locus_tag="ACG84X_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFP9128617.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            796..2148
                     /locus_tag="ACG84X_002820"
     CDS             796..2148
                     /locus_tag="ACG84X_002820"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFP9128618.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            2319..2606
                     /locus_tag="ACG84X_002821"
     CDS             2319..2606
                     /locus_tag="ACG84X_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFP9128619.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT          960 a          449 c          544 g          783 t
ORIGIN      
        1 tttcttttca tgttaagtgg attttaaaat gtaaaaatag tatgataaga cgagaataac
       61 aacgtggggt gtttacatgg aaaataagtt agtcgaagag gttatcgaaa agttaaaaaa
      121 agagaacatt cgaatcacac ctcaacggta cgcggtttta gaatatttga ttgaacatca
      181 ttcccatcca acggctgatg agatttataa agcacttgaa catcggtttc caaatatgag
      241 tgttgcgact gtttacaata accttcgctt atttacttcg attggatttg ttcaagaaat
      301 gaagtacggc gatgcttcta gccgatttga tttcagttca aagcgtcatt atcatgtaat
      361 ttgtgaaaac tgcggtaaga ttgttgattt tcattaccca gggcttgaag atatagaaat
      421 ggctgcaagc agactgactg attttgagat taatgaacat cggttggaat tgtatggact
      481 ctgtccggat tgtaaagagt cagcaaaaaa ggcgcaaatg taaaaacagt ttctacaagt
      541 gttataccta aaaaaagcta gctgtgtaaa aaaaacgcta gcttttttat ttttttgtct
      601 tttattcaca atcttagata taaaagtgaa tattattaaa ataagaatct tgtagatatt
      661 gggttcttat gcttgaaaag gaatgaaact acaaacaaac ctttgtgaat tcacaagcat
      721 taaactgttg tatccgtttt atttctgtta tagtagtttt gtcgaaggac aaaatgttaa
      781 tcggagggac cataaatgaa agtagtagta attggctgta ctcatgcagg tactgcagct
      841 gtaaaaagta ttttaaaaaa tcatccagaa gcagaagtga cagtatatga aagaaatgac
      901 aatatttctt tcttatcttg cggtatcgca ctttatgtcg gcggagtagt aaaggaccca
      961 gcaggcttgt tctactcaaa tcctgaagaa ttatcttcat taggagcaac agttaaaatg
     1021 gaacacgatg taacagacgt cgatacagaa aataaaacag taacggcaaa agatctgaaa
     1081 acaggagaaa cagaaacggt ttcttatgat aaattagtga tgacaactgg ttcatggcct
     1141 attatcccac cgattagtgg aatcgatgcg aaaaatgtac tcctatgcaa aaactacaat
     1201 caagcaaatg aaattattgc acaagcgaaa gaagcaaaac gtgtagtaat tgttggtggt
     1261 ggatatatcg gtattgaatt agtagaagct tttgtcgaat ctggaaaaca agtgacattg
     1321 attgatggat tagatcgcat cttgaataaa tatctagata aaccattcac agatatctta
     1381 gaaaaagaat tgacagaccg cggtgttact cttgcgctag gcgaaaatgt tactgaattt
     1441 atcacagatg aagaaggaaa agtgaaacaa gtagctacac caacagatac atttgataca
     1501 gatatggtca ttttatgtgt gggcttccgt ccaaatacaa aactgatcga aggaaaagta
     1561 gatacactgc caaacggggc aatcaaagtg aatgaataca tgcagacaag taatccagac
     1621 atttttgcag ctggagactc tgcagtagtc aactacaatc caagtggcac gcaaaactat
     1681 attcctttgg caacaaatgc cgttcgtcaa ggtttgcttg tgggaaataa cttgacagat
     1741 cataaaatgg cgtatcgtgg tactcaagga acttcaggac tttacctatt tggctggacg
     1801 atcggttcga caggtgtgac caaagaaagc gcaactttga acgatctaga agtccaagcg
     1861 actgtatttg aagataatta tcgtccagag ttcatgccaa ctactgaaaa agtaatgatg
     1921 gagctagtct atgaaaaagg aacgaatcgt atcgtaggtg ctcagttcat gtccaaatac
     1981 gacattacac aatcagcaaa taccatgtct ttagctgttc aaaataaaat gactgtagaa
     2041 gatctcgcac tttcagattt cttcttccaa ccacattttg accgcccatg gaattacttg
     2101 aacctacttg cacaagcagc gctaggcgaa atcgaaactg cacaataaag aaaaagggtt
     2161 gtgacacaat tttgtcacga ccctctgtct ttttttgtga aaagtacaat tagttgtctt
     2221 tcttcgaatt ttttgtcaca ataagcagca aagataaagc tgttacataa aagaacaagc
     2281 agctttattt gattttgaaa agaaaggtga gaaagaagat gaataaagaa tattttgtcc
     2341 aacaagatgc atttttagaa gattataaaa gtgcttcgaa gaaattaacg atcaatattg
     2401 atgagttggc agatcaagta ctctctcagt tgaatgaaac gcaagaggaa tattacacga
     2461 tgccagcaaa tgacgccaaa gataatgttt ctcatcgttt tcctttcagt agacgcatct
     2521 actcagatga aaatgacggc acattgaata cagagtacac atatgaaggt cagccatatg
     2581 tgctagaaac tgatgatgat ctttaaagac agtttttgaa aaggccgctc atccttaagt
     2641 gatgacaaaa aatcatcaca attaccgatg actgtctctt tactatcttt taatcagaaa
     2701 aaggggttat gacaagcttt gtcaacccct tttttt
//
LOCUS       DAZKCH010000166         2704 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000166 DAZKCH010000000
VERSION     DAZKCH010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.173"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            71..394
                     /locus_tag="ACG84X_002822"
     CDS             71..394
                     /locus_tag="ACG84X_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128620.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            558..812
                     /locus_tag="ACG84X_002823"
     CDS             558..812
                     /locus_tag="ACG84X_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128621.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            882..1127
                     /locus_tag="ACG84X_002824"
     CDS             882..1127
                     /locus_tag="ACG84X_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9128622.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            1203..1568
                     /locus_tag="ACG84X_002825"
     CDS             1203..1568
                     /locus_tag="ACG84X_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFP9128623.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1629..2192)
                     /locus_tag="ACG84X_002826"
     CDS             complement(1629..2192)
                     /locus_tag="ACG84X_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128624.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT          793 a          476 c          423 g         1012 t
ORIGIN      
        1 ataactattt tgttacttta atttttattt gcttatttta gaaaaaatgt tattctttta
       61 tttattctca atgttaggag tgattatttt gccatttatt gcgattttat tcgatttagt
      121 tgcggcagca gcttattttc tccaattaaa ttatcaaacc tcaggaattc tgtttattgg
      181 aatgattttt caaggtgtga ttaccctttt gcttcttgtc atgatgctca gctataaagg
      241 aaaaagatat gcccgtattc aaacaaaagt atttgttaaa tatgtttcca ttcgctatgg
      301 gatcatcatt ctttcctttt tagtgaatgc gatcgtcctc tttttatatg tattgaatta
      361 cttagatatc aatccattga ttttttctcg atagataaga cacattcagc ggaacagttc
      421 ctgcttatca gcagaaaact gttctgcttt ttcatttttc attgatctat tcttctttta
      481 ttttcctagc atttcatttg tgatgtatgc aataacatgt tatcttttat tatatgaatc
      541 gttgaggagt ccgttacatg attacgttgg tgagagtttt gttttgggtg cctgcggtcg
      601 cactggtcgc aagtattgtt tatcttatga attggaacaa agaacggttt tatttagcta
      661 ttttgactct tccggctatc tactttatgt ggaaagtttt taattacaac tactttgaac
      721 ccgatagtgt ttttatagaa gaattatcag gactggtttt gtctttattg atcgtcattc
      781 tttatttgat acgtttaaat aaaaaacatt gagtactatt gattgcatgt gtagctttct
      841 atagtcatta taactattct actataatga aaggtgatta aatgagtatc gaagaagcta
      901 ttttactgga tactttacgt tgtcgtctga atttcttaag aactggccga tctttatctc
      961 aagtagctgt ttctagcgcg ttaagtattc ctttattcaa atatcgtaag tacgaagaag
     1021 gagaagaaat tccaagcatc attgaattaa tctatatcgc tgacttttac gatatttccg
     1081 ttgattacct aattggtcgc tcagaaacag caagcaaact gaagtgattt tttccagcct
     1141 tggtgctggt tttttcattt aacgtctaag gttaacaatc tatatataaa ggagacattt
     1201 ctatgcgatt atggcatgaa aaattgattt caaagcttcc tcgtcaacag cttttaggac
     1261 aacatcggga atgctgtgca ttaagaggaa atggctgggg aaagaaacat gctactgtgg
     1321 attatgtttt tcactattct ccttatagat tattccaata tcatcagctt gtcatggatg
     1381 aaatggaaaa acgtggttac agcccagcac cagagtggaa aaatcctatg tatcgtggca
     1441 aatcatgcga agcatttttt gatttaccta ctgtagagcg caacgtgccg atttatccgg
     1501 aacacgatga agtttatcta gcagaatgtt tagcaaattt ggagcaaaaa ggaatttatc
     1561 ttacctaata taactagaaa agccttctat ctcctcttac ttcattaaaa agctttaacc
     1621 atcttagatc aagctaaaat gtcgtaagtt ttagggttat cttcatcctc acgtgcaaaa
     1681 ctaaaagcgt actctagttt tggttcatcg ccaacttccc tagacataaa tgaacatctc
     1741 ctgacgtggt ttaaaagtac cgcatcttcg acgtctgtat acgatgcaca gcacagattg
     1801 cttcttttga tctttctttt gatttttctg ttgcttcttc tacaccttct tcgattacta
     1861 catcgatgct tacaattgct tctgcctaat attcccatgc atcgtcgatt taagcctctg
     1921 tagtcactgt gatcgtttcc acattttaac tcctctgtcg tggcttcagt tgattttgtg
     1981 atcagttcag ttgctaagcc agagtcagaa caacctgcca ttgctagcgt taatattgat
     2041 agtaaaaata gtttttttat cataaggttc cccccctgaa aatagactaa aataataacg
     2101 ctttcttttt ttgttttcag acgaaaatta ataatttcta aatattcttt aaaaaagctt
     2161 ataactatta tgcctttttt aatatataac acagttattt ttaaaaataa gaatgctaaa
     2221 tcactctaca ataacggcga aagcacaaaa aataaaaaaa ttattacgtt attaaaaaaa
     2281 cagatgaaag atcaggtttt attagatctc attctttcat cacttgaagg gatttaatga
     2341 actacttttt cctctttgtc gtttttatat attcgtattc cttcaaacag taggatagcc
     2401 tctttcaatg cttgatattt gaactgtccg ttacttaaaa atttagatgt gccgccctct
     2461 tcctagaaca tattcttttt tactttttca ttaattgaca gaccaatcga acgaaactgt
     2521 aaatttcgat aggataatga ttggtcaaac tcattcattt tcaagacatc tcgattcata
     2581 ttcaagatag gaatcttttt atcaacatca ctttattcgt attttcctct accataaaag
     2641 cttcacgctc cacaaaattg ttttatacac tactattcag cccattcaac gaccaatgaa
     2701 tttt
//
LOCUS       DAZKCH010000167         2619 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000167 DAZKCH010000000
VERSION     DAZKCH010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.174"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..317)
                     /locus_tag="ACG84X_002827"
                     /pseudo
     CDS             complement(1..317)
                     /locus_tag="ACG84X_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
     gene            complement(349..672)
                     /locus_tag="ACG84X_002828"
     CDS             complement(349..672)
                     /locus_tag="ACG84X_002828"
                     /inference="COORDINATES: protein motif:HMM:NF015824.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFP9128625.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTHFGSVAKFSK
                     KSILV"
     gene            1134..2516
                     /locus_tag="ACG84X_002829"
                     /pseudo
     CDS             1134..2516
                     /locus_tag="ACG84X_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          940 a          456 c          433 g          790 t
ORIGIN      
        1 tttcgtaacc agatatctaa ggttaagccg tccgcatcaa ttgcacgata aagataatgc
       61 caacgtccct taattttgat ataggtttcg tccattttcc atgaatagaa ggattgtcta
      121 tttttcttct tccaaagata atagaggact ttgctgtact cttgtaccca acgataaatc
      181 gtagtatgac aaacatttat tccacgatca tatcacaatt cctgaacttc acgatagctt
      241 agattgtaac gcaggtagta accaacagcg acaataatga cgtctttttt gaattgtttg
      301 cctttaaaat gattcattac tctgtcctct ctgtcttttt tctcaatttt acactaaaat
      361 agattttttg gaaaactttg caacagaacc gaaatgagta tagtatgaat tagtaatttg
      421 gttttcatct aagtttagct ttgatttact aaaattgata tctcgataca tgttcaatac
      481 atctaataca aatcgagaat cttctttcgg aaatggctca gaaagatcac tccaaatttc
      541 atcatcataa tgatactcgt aaccttctct caatatttcg atttttcttt cataataaga
      601 tctgttttgg tcctcaaatt tagccaataa ctcaaattga tttactagtg acaatctctg
      661 aaaactgtcc attaaatgtt tcttcctatc ttgttcatta acaaaaaatt ataagccctt
      721 acaacgaata ttatatatta aatttaattg taggtgaaca cgaattttat aaatatttat
      781 ggtgttaatg acaaatgata tccgactcct cttcatacgt tctggactat ttgctaatag
      841 attaaaattt cagcatctat ttctgaccat aaataaatga gctgccgaaa agctgccaaa
      901 tcagacttga aaataaagga tcaaaaactt ttaagtttct gaccccgtaa ctcacacttc
      961 aaaatcttac ttaaaaagga gtctgaaaga aaaaaagagt attcaaaatt tttttctaac
     1021 tagctacatc acatctatgc attgacactc aaagaaccag aataagtcat cagaaagcaa
     1081 gggggtgcgg acataatcct ggacgaaaaa ataaacttag gaggaatgtc cgtgtgtttt
     1141 cccacaaaga gcgtgtaagg gcaattcagt tatttttaaa atacgattgc tcttatgctg
     1201 caaccattcg agaattaggg tatccgtcga ttggtgcact acggaaatgg tataaagagt
     1261 atttggaatc cggagagctc catcaggagc accgaaaaaa atcaaagtat tctgaagaac
     1321 aaaaacgaat agcggtgaat cattattttg aatatggtca atgttatgca cgaaccattc
     1381 gcatgcttgg ttatcctaat agagagtcct tgcggcagcg gtgtgaagaa cttgcaccag
     1441 gagctagaaa actccgaaaa agtgcggtaa agttaacaca agatcaaaaa gaagctgtgt
     1501 tgaaaaaatt ctataaaccg caaactaata ggaaaaattt agccgaatct ggaggaatta
     1561 gtagagttac tctatatcaa tggaaaaaca cggttcttgg aaaggatttt ccattgtgta
     1621 tgactttaaa aaatcaggaa aaacaaaaag agctactttt aaaggaagta gaagacttac
     1681 aaaaacaagt acaccaatta cagctcgaaa aagcattact cgaaggagcg gctgaactgc
     1741 taaaaaaaga aaaaggcgtc aatcttcttt gtctatcaaa tcaagaaaaa acgatattga
     1801 ttgatgcctt acgaaatcag ttcaccttga aagagcttct tcaacagctc cagtttccta
     1861 aaagcagcta tttttatcaa aaacaagcac ttgagaaacc agataagtat tacaaagaac
     1921 gtcaaattaa ttatcacgat tttcaatcat aacttctgtg cgtatggtta ccgtagaatt
     1981 caccaagctt taaaaaatat gggtaaaaag ctttctgaaa aagttgtacg tagattgatg
     2041 actgaggaaa atctatttgt taaattttct agacgaaaaa agtattcttc gtatgctggg
     2101 gaaatttctc ctgcacaccc caatttatta aatcggaatt ttaaagcaaa gaagccaaat
     2161 gaaaaatggt taacagatat tactgaattt agaattctcg cagggaaaat ctacttatca
     2221 ccacttgtcg attgttacga tggtgctatt gttagttgga ctattggaac aaagccaact
     2281 tgcttcactc tatgtctaaa aagagttatt caccagataa ttcagcgtgc gaaggtttct
     2341 ttggacgatt aaaaaacgag atgttttatc aacgtgactg gaagaataca acaatcaatc
     2401 agtttataaa caaattggat gattatattc attggtataa taatcaacga attaagttat
     2461 ctttaggaag gctaagccct cttcaatatc ggaagaagca aagatatatt tgttaaaaag
     2521 gtccaaaaaa aatatccgca cccccttttt ttgtaaaaaa ctattgcaca atacaagtag
     2581 cctacggcta tcgaaatttc cataactttc gagcaagaa
//
LOCUS       DAZKCH010000168         2583 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000168 DAZKCH010000000
VERSION     DAZKCH010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.176"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1269
                     /locus_tag="ACG84X_002830"
     CDS             <1..1269
                     /locus_tag="ACG84X_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFP9128626.1"
                     /translation="NYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVE
                     IGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKV
                     PVEVTDNRSNADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTA
                     GNKKGTIVVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKN
                     KEDLPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVD
                     PITEGDQIVTGKTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATD
                     ESGNTSEPTNVVVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGES
                     DSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1403..>2583
                     /locus_tag="ACG84X_002831"
     CDS             1403..>2583
                     /locus_tag="ACG84X_002831"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFP9128627.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     C"
BASE COUNT         1020 a          343 c          512 g          708 t
ORIGIN      
        1 aattacgaag gtgtcattga agtaacgtat ccagacggta cgaaagatac ggtgaaagtt
       61 ccagtagaag tgacagacaa tcgttctgac gccgataaat atgaaccaac agtagaaggc
      121 gaaaaagtag aaattggagg cacagtagat ttaacagata atgttactaa cttgccagcg
      181 ttaccagaag gaacaacagt aacagatgtt actcccggcg gtacaattga taccaacaca
      241 ccaggcaatt atgaaggtgt cattgaagta acgtatccag acggtacgaa agatacggtg
      301 aaagttccag tagaagtgac agacaatcgt tctaatgcag ataaatacaa tcctgaagga
      361 caaaaagtga ctacagactt aaataaagag ccagatgcat ctgagggaat taagaacaaa
      421 gaagatttac caaaaggaac tacttatgct tggaaagaga aagtagatgt tagcacagct
      481 ggaaataaaa aaggtactat tgtagtgaca tatccagatg gatcatctga tgaagttgaa
      541 gtagacgtta cagtgacaga tactcgttcc gatgcagata aatataatcc tgaaggacaa
      601 aaagtgacta cagacttaaa taaagagcca gatgcatctg agggaattaa gaacaaagaa
      661 gatctaccaa aaggaactac ttatacttgg aaagaaaaag tagatgttag tacagctgga
      721 aacaaaaaag gtactgtagt agtaacatat ccagatggat ctaaagaaga agtagaagtt
      781 actatttctg tagtagataa aaaagcaccg aataaacctc aagttgatcc tattacagag
      841 ggtgaccaaa ttgttactgg taaaactgaa ccaaatgcag aggtgacagt tacattacca
      901 gacggaagtc aacaccatgg gacagctgat aaaaatggta attttacagt taaagttcct
      961 aaattagagg cagggacaaa agtgatagta actgcaactg atgaatctgg taatactagt
     1021 gaacctacta atgtagttgt ttcttccaac aaaaaagaca gtggaaaaaa cggtagtaaa
     1081 ggtagtaaga ctgacaatca aggtagcaac agcaatcaag acaaaaatag aggcaaaagc
     1141 cagtcctcaa aagtttttcc taagacggga gagagtgaca gtaatatctt tactattagc
     1201 ggtggtttaa tactgttagg aacgttagga ttattagggt ataaaaatcg aaaaaaagag
     1261 aatgaataga aaatcaattt cttaagtctt ctctgagaag aggaagaatc tttttcttcc
     1321 tctttttgct tttttatgat gggaaataag tgttagttaa agatgaatat actttttata
     1381 gaaaggaaaa gaatgtaatt aagtggaaaa aatagtaatt attggttcaa accattcagg
     1441 gctagccgca gctcgatttc taaacttaag cgattcaaat tatgaagtta ttctaatcga
     1501 taaaaaatca gaaattagtt acttggaatg tgggacatcg ttatttataa aaggagaagt
     1561 aagtaattta gaagatcttt tttatcaaaa tagaatgaca ctaaattctg agataaaaaa
     1621 gttatttcta gagacagaag ttgacaaaat tgatattcaa aataaaaaga ttagttgtgt
     1681 aaaaaaagat ggtacaagat tctctcaaga atatgacaaa gttatattag ctacaggttc
     1741 aaagcaaatt atgctagata taccggggaa taatttagct aatatttttt cgataaagaa
     1801 ttttccaaat gcaaaagaga tttttaaagc tttggatgat agtactatta aaaaagtagg
     1861 aattattgga gcaggatata ttggagttga aattgctgaa gccataagaa aaagagggaa
     1921 agaagtatat cttttcgatg ttgcagatag agtgttgtcg acttattacg accgtagttt
     1981 ttcagataaa gttgaagaaa tactatcaaa aaatggaata catctttgtc tatcagaaag
     2041 tcctaaaaaa tatttaggaa gaaaaaagat tgaaaaaata gtcactacaa gtggtaccca
     2101 atactctatg gatatggtcg tacaagctat aggatttcta tctaatagtc caattgggga
     2161 aaaggaactc ttgagagatg ttagtggagc atatctaact aatgaatacc agcaaacaaa
     2221 tataaaagat atatatgcta ttggggattg tgctacaact ttttttacgt ccattaatag
     2281 aagtagtgtt gatttttcta tttctaatgc tctaagaaca gcttatattg caactcaaca
     2341 tattaacaat caagatttta caccttctgg ttcccaattt acaaatggct tttctatatt
     2401 taattacaat ttttacgcag caggtttgaa tttaaaaaca gcacgattat taagtgagtc
     2461 tatagattat atagaaatag aagatttcat tagacctgct tttttgagaa aaaatagtcg
     2521 tgtaaaatta agaattagct ttgaaaaaaa tacaaagaga atagtaggtg tacaactttg
     2581 tag
//
LOCUS       DAZKCH010000169         2580 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000169 DAZKCH010000000
VERSION     DAZKCH010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2580
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.177"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            38..1045
                     /locus_tag="ACG84X_002832"
     CDS             38..1045
                     /locus_tag="ACG84X_002832"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HFP9128628.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1057..2061
                     /gene="neuB"
                     /locus_tag="ACG84X_002833"
     CDS             1057..2061
                     /gene="neuB"
                     /locus_tag="ACG84X_002833"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HFP9128629.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2058..>2580
                     /locus_tag="ACG84X_002834"
     CDS             2058..>2580
                     /locus_tag="ACG84X_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFP9128630.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAP"
BASE COUNT          943 a          333 c          517 g          787 t
ORIGIN      
        1 aattatagat gactataatt cataggagga gatataagtg tttaaaggaa aaacaatatt
       61 agtaactggc ggaactggtt ccattggaag tgaaattgtt cgtcagcttt taaaatatga
      121 accaaaagct atcagaattt atagtagagg tgaagaaaaa caattttata tgcaacaaga
      181 gctctcaaat cacactaatt tgagattttt aattggtgat atcagagact ctcaaaggat
      241 tgattatgca tgtcgtgatg tggatattat ttttcatgct gccgcaatga aacacgttcc
      301 agcaagtgaa tataatccta tggaagctgt aaaaacaaat gtgatgggaa ctcaaaatgt
      361 aatagatgca gcgatcaaaa ataatgtaaa acattttgta ggtatcagta cagataaagt
      421 agtgagtcct actaacacca tgggtgcgac aaagttattg agtgaaaaat taataatagc
      481 tgccaatcag tataaaggaa aaacagaaac aatattttct tgtgtaaggt ttggaaatgt
      541 catggggtca agtggatctg ttattcctct ttttagtaaa caaataaaaa acaataaaga
      601 tattactttg acagatgttg atatgacacg atttatgatg tcaataccgg atgctgcaag
      661 attagttctg tctgctgcta tgaattcaaa atttggagaa acatatgtct taaaaatgcc
      721 ggcaatcaat attttaactt tagctcaatc attaataaaa atatataatg atacacatga
      781 tgaaaaatat agaggtgaaa taaaagttgt aggtatcagg ccaggagaaa aattatatga
      841 agagctaatg actacagacg aaattgaacg ctcatatgaa aatgataaaa tgtatatcat
      901 tccaccacac tatcatgcta ctgacgaact gtacaaagat tatgaaaaaa ttaaaatcac
      961 tgcatactct tcagatgcaa cagaattaat gagtggacag gaatttatta gaatcgcaaa
     1021 agagaataat gtcgtgactt ggtaaggagt tttatgatga aatcagaagt atatgtaatt
     1081 gcagaaattg gtgtaaacca taatggaagt ctagatttag ctttagaaag tattgataaa
     1141 gctaaagaat gtggagctaa cgcggttaaa tttcaaacat ttaaaacgaa taagctagtt
     1201 tccaaaaagg ctccaatggc aaaatatcag aaggataatc ttaaagagga cagttctcaa
     1261 tttgaaatgc taaaaaaatt agaattatct caatctgatt ttattagaat aaaagattat
     1321 tgtatacaaa ataaaattga ttttttgtct actccttttg atgaagaaag tgcagacttt
     1381 ctaaaacaaa ttggtgtaca aggatttaaa attggctcag gagatttaac aaatttacct
     1441 tttcttagaa aaatagatat gtatgggttg ccagttttat tatctacagg tatggctgat
     1501 attcatgagg tcagtgaggc tgtagattgt ttcatagata gtccagttac tattttacat
     1561 tgtacttcaa attatccggc tagttctgaa gatattaatt tattggcgat taacacatta
     1621 aaagaaatgt tcgggatacc cgttgggtac tccgatcatt cattgggata tgatgttggt
     1681 atttgtgctg ttgcgatggg tgctaaggta attgagaaac attttacctt ggataaggaa
     1741 ctacctggtc cagatcataa agcttcttta gatcctcagg aatttgcaga ttttgtaaag
     1801 catattagaa acactgaaat atttttaggt gatggtgtta agcgagcaat gccttctgaa
     1861 cttagtacaa aagaagtatc aagaaaaagc ctagtggtca ctgagaattt aaatgtggga
     1921 gatattctta cagagaaatc tcttacaata aaacgtcctg gaaatggaat agctcctaag
     1981 tttttatatc aatatattgg caaaaaagtt aaaagaccaa taagtgcaga tagtgttctg
     2041 cttgaggaag atgttgaatg aaaaaaatac ttatagtaag tggaacacga gctgattatg
     2101 gaatatataa acctgttgct gagaatttac tacaagataa ttgggatgta tcatttgttg
     2161 tttctggaat gcatttatcc cataaatatg gatttactaa agaattgatc ttagctgacg
     2221 gatttagaat tagtggagaa gttcaaagtt tgtttttaga gaacaataag ggaaacatgg
     2281 ctcggtctgt ggcattagag ataaatggtt tcacaaatat atttgaacaa actagccctg
     2341 attttgtatt attactaggg gatagaggag aaatgttggc agctgcgata gcttgtttgt
     2401 atcttggaat caaaacagca catattcacg gaggcgaagt gtctggtact gtagatgaat
     2461 caataagaca tgccataacg aaaatagcat ctgttcattt tgctgctacg gaaaaaagca
     2521 aagagcgttt aataaaaatg ggggaagatt cttggagagt ttttcccgtc ggagctccta
//
LOCUS       DAZKCH010000170         2459 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000170 DAZKCH010000000
VERSION     DAZKCH010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.178"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..1150
                     /locus_tag="ACG84X_002835"
                     /pseudo
     CDS             6..1150
                     /locus_tag="ACG84X_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            1321..1779
                     /locus_tag="ACG84X_002836"
     CDS             1321..1779
                     /locus_tag="ACG84X_002836"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFP9128631.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..2408
                     /locus_tag="ACG84X_002837"
     CDS             1938..2408
                     /locus_tag="ACG84X_002837"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFP9128632.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          823 a          460 c          460 g          716 t
ORIGIN      
        1 gaaacatgca cattcaaaca aaattgatcc acggaggcat cagtgaagat cccacaacag
       61 gagctgtcag tgtacctatt tatcaaacat ccacttatcg gcaagatggc gtcggccagc
      121 ctaaacaata tgaatattca agatctggta atcctactcg ttttgcattg gaagaactga
      181 ttgctgattt ggaaggcggt gttcgaggat tcgctttttc ttctggtctt tctgggattc
      241 atgccgtttt ttctcttttt caagctggcg atcatatctt attaggagat gatgtctatg
      301 gaggaacatt ccgtctattt gacaaagttc ttactaaaaa tggtctcgag tacacgatca
      361 tagatacgag taatcttgat aaaatagaac aatccatcaa acccaataca aaagcacttt
      421 atcttgaaac acctagcaat ccgcttctaa agattactga tttagaaaaa agtgccactc
      481 tggctcatca acatggattg atagttattg ctgacaatac atttgctact ccttattttc
      541 aaagaccttt agatctcggt tctgatatcg ttgtccatag cggtaccaaa tatctaggcg
      601 gacacagcga tgtagtagct ggtttagtga cttctaacca aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttctttaact taataaaaat aaaaaaagat gaactatttc tagttcatct ttttgcctt
//
LOCUS       DAZKCH010000171         2429 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000171 DAZKCH010000000
VERSION     DAZKCH010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.179"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(44..982)
                     /locus_tag="ACG84X_002838"
     CDS             complement(44..982)
                     /locus_tag="ACG84X_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFP9128633.1"
                     /translation="MKKIDEKLAAEISLKKPAVSNSRLSNSRLSGQTLGKSQPALSFD
                     AMTIVGNLNKTNAKKLSDFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWD
                     RRNMRVEFNPNKLTHEEMIWLKQNIIDYMEDDGFTRLDLAFDFEDDLSDYYAMTDKAV
                     KKTVFYGRNGKPETKYFGVRDSDRFIRIYNKKQERKDNADVEVVSEHLWRVEVELKRD
                     MVDYWNDCFNDLHILKPAWATLEKINEQAMVYTLLHEESMWGKLSKNTKTKFKKLIRE
                     ISPIDLTELMKSTLKANEKQLQKQIDFWQREFRFWK"
     gene            1473..2429
                     /locus_tag="ACG84X_002839"
                     /pseudo
     CDS             1473..2429
                     /locus_tag="ACG84X_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
BASE COUNT          839 a          422 c          390 g          778 t
ORIGIN      
        1 ttaattatac tgaattagca atttttatca aataaaactt attttacttc caaaacctaa
       61 attcacgttg ccaaaaatca atctgctttt gcaattgttt ttcgttcgct tttaaagtcg
      121 atttcattaa ttccgttaaa tcaattggag atatttctct aatcaatttt ttaaatttag
      181 tcttagtatt cttacttagc tttccccaca tactttcttc atgcaacaaa gtataaacca
      241 tagcttgctc attaattttt tctaaagtag cccacgcagg tttcaagatg tgtaaatcat
      301 taaaacaatc attccagtaa tcaaccatat ctctttttaa ttcaacttct acacgccata
      361 aatgttcaga cacaacttca acatctgcgt tatctttacg ttcttgtttt ttattataaa
      421 ttctaataaa tctatcacta tcacggacac caaaatattt tgtttctggc ttgccattac
      481 gaccataaaa aacagttttc ttaactgctt tatcagtcat tgcatagtaa tcgctcaaat
      541 catcttcaaa atcaaaagct aagtctaatc ttgtaaaacc gtcatcttcc atgtagtcga
      601 taatattttg ttttaaccaa atcatttctt catgtgtgag tttattggga ttaaattcaa
      661 cacgcatatt acgtctatcc caagtatctg cttttacttt gtcatattcg atataaactt
      721 tttcttgaag tgccttagct ttaaactttg tttgaagtat atcccaaagt cgtatttgtg
      781 gctctacact cataaagtca gatagctttt tagcattagt tttgttcaaa tttccaacga
      841 ttgtcatggc atcaaaactt aatgcgggtt gagattttcc caaagtttga ccacttaacc
      901 ggctattact taaccggcta ttagagacgg ccggtttttt tagtgagatt tctgcagcta
      961 atttttcatc aattttcttc attttttatc gctcctaaaa taatttttgg aacgaaaaaa
     1021 ggacgagtgg aatcgcaaaa taaatttcgc ctgtatccat tcgtccattt tgttttgtat
     1081 tcaaaatcaa aaattgatat actaatcatc gaatgaataa caagtgtggt ttgttattcc
     1141 gggcgagaac gttggtagcg ttgctcgtct ttttttatgt ctttttttcg ttaaaactat
     1201 tttaaaacta aatatatctt aaagcaaata aattcaaggg gctaaaagcg ccccttaaaa
     1261 accccttgcc tctgaaaagt tttgtgtttc ctttccgtcg gtttcaaaag ctaatttact
     1321 caaaaaaata gatcaagggt aaatgcactc actgcgttcg cccttgagct attttatttc
     1381 gcaaatttta acgcatttgc cgacgaaaag ataaaacaca taaaaatata cgcagatata
     1441 tttaaaacgt cttagaacgc aaaattttac gtttaaaagc tatgcaagga ctgtatgaag
     1501 caaaattatt gagttatcca agaacagata caccatttat tacagagaac gaatttgctt
     1561 atttaaaagc gaattttggc aaatatagcg gttttttagg acttgatctt gaaatggttc
     1621 aaacagagcc tagaaagcgt tatgtggacg gtagtaaggt acaggaacac cacgccatta
     1681 tcccaacaaa acaagtacct accgaatctg cattagcgaa aatggacgat ttacaacgaa
     1741 aaatttatgc tttagtcgtt aaaacgaccg ttgccatgtt tttacctgat tacttgtatg
     1801 aagaaaccaa gatacaaacg aaagtagctg atttgctgtt tcaatcgatc ggaaagacac
     1861 caaagcaaga agggtggaaa attcttttca aacaacaaac caaagaagaa aaagaggacg
     1921 ttcaaacgtt accactcgtt atcattggcg aacgtgccga agttggtgtt aagagtgttg
     1981 aaaaagaaac gcaaccgcca aaagctttta cagagggtac attattaact gctatgaaaa
     2041 cggcgaataa aacggttgat gatgaagaag caatcaagat tttacaagaa gttgagggga
     2101 ttggaacaga agcgacaaga gcaagtatta ttgaagcgtt aaaacaaaaa gaatatatcc
     2161 aagtgattaa gaataagctt gttgtaactg aaaaaggaaa attattgtgc caggcagttg
     2221 aaagtcagca ccttttaacg agtgctgaaa tgacggctaa atgggaaacg tatttaaaaa
     2281 aaatcggtaa aagagaaggc aatcaagaga actttattac gaatatcaaa aaattcattg
     2341 ttcatttact ggaagctgta cctaacgata tagaaaaact aaatttttct gattaccagg
     2401 aacagaaaga aaaagaagca gaaaaaagt
//
LOCUS       DAZKCH010000172         2385 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000172 DAZKCH010000000
VERSION     DAZKCH010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.180"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            197..2059
                     /locus_tag="ACG84X_002840"
     CDS             197..2059
                     /locus_tag="ACG84X_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFP9128634.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2059..>2385
                     /locus_tag="ACG84X_002841"
     CDS             2059..>2385
                     /locus_tag="ACG84X_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFP9128635.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKN"
BASE COUNT          857 a          353 c          465 g          710 t
ORIGIN      
        1 aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt ttaacagtac
       61 atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct ataagttgca
      121 cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta tattagcaat
      181 gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt tgatttactt
      241 ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa atgttagtgt
      301 tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc ggaagcaagt
      361 cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg atcgaatcaa
      421 attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc aaagtctccg
      481 aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg gaatgaaaat
      541 ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg tgctggaaaa
      601 taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt tttggatcat
      661 aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag agttcacgga
      721 ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg aatactttga
      781 aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa tcattcgaat
      841 gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat tactaaatat
      901 tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga ttggtcgtta
      961 tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg tcatgcagca
     1021 ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata tctatagtga
     1081 tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg tgatttataa
     1141 agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga cgaatctgta
     1201 tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat ataatccttt
     1261 taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc aagcagttcg
     1321 acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat atattgcctt
     1381 acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag ccgtctacat
     1441 ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg aagaattaaa
     1501 taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga ttgctaccaa
     1561 agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc ctttcatcaa
     1621 agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa taaaaaaaat
     1681 acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa cgtccatcaa
     1741 taaagatact ttagaagact ttagcaagga attgattttg aaagcttata cgatttatga
     1801 acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag cttttttgct
     1861 tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg cagaaggtcg
     1921 tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg aagcagtttt
     1981 tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct catatataaa
     2041 agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat cgaggaaagt
     2101 caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt agtagaacat
     2161 gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa tgagatgctg
     2221 aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt caaagaagta
     2281 tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa tttaaccgat
     2341 gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaat
//
LOCUS       DAZKCH010000173         2366 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000173 DAZKCH010000000
VERSION     DAZKCH010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.181"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(243..611)
                     /locus_tag="ACG84X_002842"
     CDS             complement(243..611)
                     /locus_tag="ACG84X_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFP9128636.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            761..1243
                     /locus_tag="ACG84X_002843"
     CDS             761..1243
                     /locus_tag="ACG84X_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFP9128637.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            1280..2290
                     /locus_tag="ACG84X_002844"
     CDS             1280..2290
                     /locus_tag="ACG84X_002844"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFP9128638.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
BASE COUNT          834 a          364 c          470 g          698 t
ORIGIN      
        1 attttttcct tattcaaaag ttttgcagga aaattgctga aaaaataatt ttactaagta
       61 gaaaattcaa agccattcaa tcagtgattt ttttcagcac aagaaagact ccttataaaa
      121 atagcagata ctttgtcaat taagtgttta accagggatg ataaaaagga taggattgaa
      181 caaaacctgt ataaggtgat gaatagtttc ctcgccagta aaaggtttat tcgtataaag
      241 ctttatcgcc aaaatttatc atgacctttt ttatcttcaa tattaaatga aatcaattgt
      301 tcaatcaatt cccagttgat tacacttttc caaggaactt tgatgacgtt atccgtatat
      361 acgtagcctg cttcttggat atttttttca agggcacgaa tcgctgcttt ttccggtgcg
      421 atagaaaaat gatttttagc aaaactaaat gcaataataa aggtaccatg gtcagtaaac
      481 ataggttggt tccattttac agttgtgtct agctggggat acgtttctgt tatcttagca
      541 aaaaggtctt tgatcttttg ttgatgttct ttttctttga tttgattgat gatcggctga
      601 aatttttcca ttctaaaacg cctccattaa gtggtttgat ttattttacc agaaaaacaa
      661 tagttatgta taaaaaacga acaaaacaca agtaatgttg taaccgctat atttatatga
      721 taagatgtct caaataataa aatagaaaag agacataaaa atgattgact tggcaaagaa
      781 attcttacac gaaaatatat attttgagtt gtatcatcat cgagccattt atacaaatga
      841 agatgctttg gtaataaaga aagaacaagg atttacaggt acagagacca aaagcttatt
      901 cttaaaagat aaaaaagata ataactacgt atatctgact tttactacga aacaaacgga
      961 tttcaaagca ttagggaaga tcgtcggtaa aaggctttct attgtttcat cagaacgcat
     1021 ggaagaacaa acgggacaaa agcagggcgc tgtttctccg tttggttatg aaaaacagat
     1081 tccgattatt attgatgaag agctcttatc aaatgaaaaa cttgtttttg caccaggtag
     1141 accagatcaa acgatggtca tccaaacggt tgacttaaac aaaatcatcc agctacttga
     1201 gatgccgata tttttgatgc cggcaaacga aaaaaacaat taaccaagta aaatagtgca
     1261 tacttggagg tgaagcaaca tgataagtta tccattatta gaaagaaatg caacgattgg
     1321 ggttactgca ccatcctcag gcgtatcaga ggaacaccat tcgttactcg aatcagcttt
     1381 aaagagaatg gaagaaaaat ctttccaagt agttactgga aagacgcttt ggacgcaaga
     1441 taaggaaaaa tcaggtccag caagaaaacg agcagatgaa ttcaatcaaa tgatgcaaga
     1501 tgaaaatatc caaatgatct ttccgacttg gggaggagaa ttattgattg agattctcga
     1561 ttttgtcgat tttgatgctc tacaaccaaa atggatagta ggttattcag atattagtac
     1621 gttgctactt gctgtcacat taaaaacagg gatagccact gcacatggaa ctaaccttat
     1681 tgatttaaga ggagagtact tggatgaaac gacagcaatg tgggaaagtg tactgaaaac
     1741 aagagaagga gaatcgattc tacagcaatc ttctgaaaag tatcaaaaag tgtggcccca
     1801 tgagcattca tcatcttctg ttttccatct cactgaacca acaaattggc aatcagtcag
     1861 cggagatgca gtaaggatga agggacgatt attaggtggt tgtattgata cgatcaggca
     1921 tttaatcggt actccttatg gagatgtcca atcttttaaa agaaagtata atgatggaaa
     1981 gccgatcttg tggtttctag aaaactgtga gctatcgtca gttgatttaa gaagatcact
     2041 tgttcagatg aaactggcag gctggtttga tggcagctcg gggatcatgt tcggtagaag
     2101 tgcggcagag gatttgttag attataaaat gaaggatgta tacgaagatc tgtcaaagga
     2161 attaaaacta ccgatcttgt atgatattga ttgtggtcat gtaccgccac aactgacatt
     2221 gattaatggt gcctatgcag aagtagcggt agaagataga aaagcgactg ttttgcaaac
     2281 gtttatttaa aaaatttttt cctgccttgg agtctatcaa agaccaataa atctaaatag
     2341 aaaagaaagt gaaagaagct gacaaa
//
LOCUS       DAZKCH010000174         2312 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000174 DAZKCH010000000
VERSION     DAZKCH010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.182"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            12..2165
                     /locus_tag="ACG84X_002845"
     CDS             12..2165
                     /locus_tag="ACG84X_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFP9128639.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          794 a          413 c          515 g          590 t
ORIGIN      
        1 aaggatagga aatgatgaaa gattttatga aaaaaatatt aaatacttct tggttagaaa
       61 aaataagaaa aggtgcacaa gaacctaaga acaaaacgtt tcgccggtcc catgttcctt
      121 ttcgcttaaa ttttcttttt ttcattatat ttacgttatt tgttgcgttg attgctagat
      181 tgggttattt gcagatcgtg aacggcgaag agatggaggc gcgagtgaag tctacttcta
      241 cgattacggt ccaagaaagt actcctcgcg gaatgatcta cgactccaca ggaaaagctt
      301 tagttacgaa taaagcgaat caggccatca catatacgag aggaacacaa gttacggcta
      361 aagatttgct tgaaatcgca acgaagctga actcgctgat cgatgttccg gtagatgaaa
      421 atctgacaga tagagataaa aaagattttt ggctggctga tcccaaacat ttgaaagaag
      481 ccacaaaaag actttcggca aaagaaaagc aattagggaa cagcgaacaa tatagtgcga
      541 tggtcaataa agtcacagct gatgagatta atttaaacga ggagcaatta aaaattgcta
      601 ccatctttaa acggatgaat agtgcatatg aattaaacac tgtctatatc aaaaactctg
      661 gtgttactga tcaagagtta gctgttgtgg cagaacgcgc ttctgaactt ccaggagttt
      721 cgactggcac agactggaca cgagaatata atgcagcaag ttcactgaaa agtattcttg
      781 gcagtgtgac gactgaaaag caaggacttc cagcagatga agcagagaaa tacctagcaa
      841 aaggttattc tcggaatgac cgtgtaggac aaagttattt ggaaaaacaa tatgaagatg
      901 tcctgcaagg aaccaaaacc caatatgaag tttcccttga taatgaagga aatgtttcga
      961 atcaaaaaga aatcttctct ggggaaaaag gttctaattt aatgttatct atgaatgcag
     1021 aattccaatc aaaagtagaa gaaattttga aaaggaatta tcaaacattg atcaacaacg
     1081 gcaaagcaca gtattcgcct ggtgcttatg cagtggctat gaatcctcag acaggagaag
     1141 tgctagcaat gactggtttc agtcatgaac aaggttccaa agaaatcacc gagaatgctt
     1201 taggcacgat tactagcgcc tttgatccag ggtctgtagt caaggctggt actttgacag
     1261 caggctgggc aagtaacgcg atcagcggaa atcaagtttt gattgatgag ccgattcgtc
     1321 tgcaaggtgc ttcagaaaaa agctctgtct ttaatcgaag cggacaagtt gctcttgatg
     1381 cagtcaaagc atcggaattg tcttctaata cgtatatgat caaagtggcg ttaaagatgt
     1441 taggactaga ctatacacct ggaatgggac tacctagttt agatgaagaa gctaaagctt
     1501 atcagcaatt gagagactct ttcaaagagt ttggtcttgg tacaacgact gggatcgatt
     1561 tgccgaatga atctcctggg atctcacgtt ctgttgatta tatgaagaag ttcaatgcgg
     1621 ataatggcaa agaatggtat gctccaggta actttaccga tttggcattt ggacagtttg
     1681 acacatatac accaatccaa ttagctcaat atgcttcaac agtcgctaat ggcgggaaac
     1741 gagtacagcc gcacctagtc aaagcgatct atggcaatga cgaaaatgga aacttgggtg
     1801 aagtgaagaa agaaattggc acaacagtag aaaatacggt caatatttct gcagaaaata
     1861 tggcgatcct ccgtgaagga ttccaccaag ttgtccatgg taccgatcct tacacaacag
     1921 ccaaaccatt agccagtgcg aaaatggacc tttccgcaaa aacagggact gcagaaacgg
     1981 ttgcggaagg tcatccagat attgcgacag tcaatagtaa tatcgtggca tacggaccaa
     2041 cagacaatcc ggaaattgcc atcagtgttg tcttgccgaa cttattagac gaacaagacc
     2101 acataaactt gacgattgct aaagaaataa tggacgcgta ttatgatatg ttcatggcaa
     2161 aataaaaaag aggtcgtgaa aaagccgctt agtttcgagt atgaagaaaa attttgtgaa
     2221 aatagcttct cacatttttg cttaaatttg acttcatacc gagaaactgg cttttgaaca
     2281 ccgtttactc ggcaaaaaag gttgtgacaa aa
//
LOCUS       DAZKCH010000175         2304 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000175 DAZKCH010000000
VERSION     DAZKCH010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.183"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            192..446
                     /locus_tag="ACG84X_002846"
     CDS             192..446
                     /locus_tag="ACG84X_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFP9128640.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            447..764
                     /locus_tag="ACG84X_002847"
     CDS             447..764
                     /locus_tag="ACG84X_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFP9128641.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1323..2258
                     /locus_tag="ACG84X_002848"
     CDS             1323..2258
                     /locus_tag="ACG84X_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128642.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          840 a          311 c          434 g          719 t
ORIGIN      
        1 ggatgttaac ggaagtgtat ggtgagtagt tcactcgtat tttgatatcg tttgtatatg
       61 ttttcagcgt tctaagtggc ttattttgtc caataataat atggagtgga atcccttaag
      121 aaacaccgtt ggcaattgtt gttataacat gttataattt attcatcaaa aactaaaagg
      181 agtgtgataa catgggaaaa gaactaaagg ttagaaagat cggcaatagc gtgggagtga
      241 tccttccaag ctctcttgga ttaaaaagcg gagacattat ccaagccaaa caagaaggca
      301 acttattcat attagatact actcaaatag caaaagaaca cgatcgcaaa ttgattgaag
      361 aaagtttcca agactttgag aaaggtttaa cagtttcaga aattgaaatg gtaaaagctt
      421 tcggaaaata cggctggagt gaatagatga aagagtacac gctagtttat tctaaaagtt
      481 ttcagaccag ccttgaaacg ataatagaag aatgggaaaa tgagcttgct ctttctccag
      541 ccagcataaa aagatttgta ggtgcgatcc agaaggcttt agaactaacc aaaaattttc
      601 caactatgca tgaggaagtt tccgaaatct atggaatgga tatcccaaca tatcggatcg
      661 tgatcggcaa aagctatgcc ttattttatc ggatcgacca tgaaaaaaaa gagatacttg
      721 taggacgtat tttccaatct aaacaaatga aactaggctt ttaacaataa ttaggaaaaa
      781 gtcgctcatc ctctacaggt gggtgattaa tgccgctcga tatggttgtt aaccgtcggt
      841 tactcgaaga ttgatatata agacttagta cctttttatt ttgctccatg ttatggccga
      901 aggtctaaag atacaatcat tagtctagag aaaaattaag aaccgtagga actacgggga
      961 tcgcttggtg aataagagac actgctatta gtgaaaaaat aagatatcaa gtacgctcta
     1021 ttcccaaaaa tttcgtgact ttactcatga gaggttcaag tagtatattt ttaatcaaaa
     1081 ttgacgtaac ttttaataaa tactacctaa ataaggtagt atttattttt gtgttttaaa
     1141 agaggaagtc caatatatct atgggaaact tcttaaatat tatgttggta catgaaaata
     1201 tacatccctg ctagactatt tacaacattt tactttgtac gtattcttgt tttaaaagga
     1261 atgggataaa atataggtac aataactatt tgatgctaaa tataattaat ggaggagaga
     1321 tagtgaacat acttaatgaa aaaagatatg tatggtttgc tggtaaaaaa tatattacta
     1381 ctttcaaaag attatccgag ttaatgcagc agactgttaa aagtgctatg cctgaaggat
     1441 acaagtttaa ttttgttcaa tcttcagtat ctactgaaag tatctatttt tcaattcttt
     1501 ctgagagtag gctttttcat tttagaataa gttctcatgt aaagaaaact gatgttgata
     1561 tatatacgtt ccgtacaaat aattataaaa atttaaatga tttgagtaga agtatcagtg
     1621 aatatctcaa ggggaatagc tatctcaaga ttcgattttc acatatatta attttactac
     1681 catatttgaa tgagaatttc accctaattc aagtagataa gtctttcatt gcctcaggta
     1741 atcaaggaaa tatgaatatt acaagtaaca aaacgtcacg tgtgctattg gcgttgatgg
     1801 gttacggaat tctttataga gatgaccaaa atggccagat tctaataaat cgggctgggc
     1861 gttcattatt aatgaaatat agaaaattta taccggaaga ttttcaaaac ttacagttag
     1921 aaaacatgcg tttagaagat ttatttagat tagcagaaga tgataagtat agatttgaag
     1981 ttttgaaaat tcaaaagaat gaactattga ataagttata tcctgagaat gcgataaaag
     2041 cacattttgg tgatgctaat catatgtata gttggttcat tcctaaaaga tttagaggga
     2101 aaatcaatgc tggagatcaa gtgaaagtac tcaatcgaaa tagtacagat gtcgtaatga
     2161 taacagatat ctatgtagaa gatgaagata taatcaaata tatgaagcct gtgataaaac
     2221 ttgttaataa aaataaagga acccgtggtg ctagttaatt ttttcctaga gaaaaatgtc
     2281 taaacatgtt ggtaaatcaa caaa
//
LOCUS       DAZKCH010000176         2199 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000176 DAZKCH010000000
VERSION     DAZKCH010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.184"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(162..1088)
                     /gene="cysK"
                     /locus_tag="ACG84X_002849"
     CDS             complement(162..1088)
                     /gene="cysK"
                     /locus_tag="ACG84X_002849"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFP9128643.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            complement(1228..2115)
                     /locus_tag="ACG84X_002850"
     CDS             complement(1228..2115)
                     /locus_tag="ACG84X_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFP9128644.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
BASE COUNT          614 a          486 c          364 g          735 t
ORIGIN      
        1 aaattcaatt ttattgtatt ttaatgaaaa aagacgtaaa acagtcgcgt tcactattct
       61 acgtctctat tcaaataatt tttctcatca taaatttttg tgtgttcttt tcatctttaa
      121 aagtttttta cataaaccta tctggagaaa aaccaagtgc cttatatctc ttggtaaagg
      181 gctgtagata aataacgttc accattgtcg ggaaccacag ctaatacctt cttgcctttt
      241 cctaattctt ttgcgacttt tagcgcggca gcaattgcag cgccagatga gatgcctact
      301 aaaatccctt cttttcgccc aacttctcta gctgtttcca tcgcttcgtc tccactaata
      361 gaaaggactt tatcatacac agaagtatcc agtgttttag gaacaaaacc tgtaccgatt
      421 ccttggattt tgtgaggtcc cgcttctttc ccttctaaaa tagcagattc tgctggttct
      481 accccgatta attcgatttt cggatacaca cgttttaatt ctcggccagc gccagtgatc
      541 gttcctcctg taccgatacc tgcaacaaac gcgtccaagc catttactcc aaatgcttga
      601 tgtatctcag gaccagtcgt cttctcatgc acaagaggat ttgcttcatt ttcaaattgt
      661 aatggtaaaa agtagccgtt ttcttttgcc aaacgttctg cttctctgat tgatccagaa
      721 ataccatccg caccaggagt caaaatcaac tctgcgccgt accctttcat caataaacgt
      781 ctttcgatac tcatcgtctc aggcatcacg atgattactt tatatccttt tgcaactcct
      841 accatcgaca atccgattcc tgtatttcca gaagtaggtt caatgatagt atcacctggt
      901 ttcagtagac catcgtgttc tgctttttct atcatactta aagcaatacg atcttttaca
      961 cttcctcctg gattaaaaaa ctcaagcttt acaaaaacat ctgctgaatc ttctggtacg
     1021 attttattta atttgacgat tggcgttttg ccaatcaatt cggtgactga gttatagata
     1081 gctgtcatct tcaattcctc cttgtctttg ctcttcttac ttatcataat acaatctgtt
     1141 catttatggc gagtgattcg tctttgacta gcaaaaaaaa gacaaagata taccatatat
     1201 ggtaatttct ttgccttttt atctaaatca aacgtttagt tcttgaccaa ctaataaaga
     1261 ataactggac atagacatgc catttttcgc cattagatca tcaacagaca tgccaaattt
     1321 ttgtgcaata tcccatagcg tatcacctga cacgactgta tatgtctgac cattatttgt
     1381 atttacatct gttgttgaag atgatgacgt tgaagtcgtc gtagtagtcg ttgttgttgt
     1441 acttgtggtt gttgtagccg aacctgttga tggcgtatca aaacgggtta aattataagt
     1501 attaatcaat gagttcaatt tggccccata atttggatcg gtagcataac gacctgtcaa
     1561 gtacgctgtt gcatcataaa aacttgttgt attgcttttc cacacgccag cataatgata
     1621 atcgcccgtg gaaaaactgg ttgaacgaag aacattcgca tggtcttgga aggattccca
     1681 ataagaagaa tattttcgga atggctcatt catcgttacc cattgtccgt ttacatattc
     1741 tttggttgcc atataaacga cctgtccgtt atagcttcct ttcacaccga atagattata
     1801 atttggcgca ctagctaatc cggaagtgcc atatgcactt tccaacaacg cttgagcgat
     1861 catgactgaa gcatacaagt cattacttgc agcaacttct gacgcagacc agccgatttg
     1921 atcgataaac gcttgaggat cagcgactgt ttgagatcct tgttcatctg catgaacatg
     1981 ttgcggtacc gctgtaacca tcatcggccc aactaaaaga ctcgttccaa ttaaaggagc
     2041 aatcgctttt ttattgatca ccatttttct tttaggtcta tggtgccggg cactgcgggt
     2101 cttcagctct tgcattcaaa ttcctcctca aaataaaaaa acttaataaa aagttctctt
     2161 cttaaaacaa acttaattaa ttaaattata cttttaatt
//
LOCUS       DAZKCH010000177         2039 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000177 DAZKCH010000000
VERSION     DAZKCH010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.185"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..425)
                     /locus_tag="ACG84X_002851"
     CDS             complement(<1..425)
                     /locus_tag="ACG84X_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFP9128645.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
     gene            complement(534..1565)
                     /locus_tag="ACG84X_002852"
     CDS             complement(534..1565)
                     /locus_tag="ACG84X_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9128646.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          627 a          331 c          351 g          730 t
ORIGIN      
        1 ggaatctgtt ttgattttgt tccatttgaa atttctctca ctcgcttttt tgtctcatca
       61 tcaaataaaa tgaaagggtc ttctaaacga tcgataaata cttccattgt tgttgttggt
      121 agatgataag aagtcatgac aggcactgca ccaaggtaag acacagaaac agctagaagg
      181 tatgtgtcaa aagcggaact cttataaata ataactttgt ctccggattt cactccaaga
      241 tgagccaatt gataagcccg tttcaacaca ctttcgcagc attttttgta agttgtttca
      301 agtcctaatt ctgggaaagc tgaaagtggc tcatcaaaga taatcggggt ctcggaaaag
      361 ttagctgcag cttcttgaaa attcgtaaat aagttcaaag gggaatacgt tatggtctcc
      421 atcattcaca ctccattatc ttttgttaag taatatacaa attcaagata atcgtaacat
      481 aatcctttat ataataacat agtttattgt gaaaaaaaga tcatacattt gttttatatg
      541 gaagaaaccc gaacgaatgc cgctaattcg tgataagaaa aatcaaccat cttttcccag
      601 atatcttgaa aagaatggga tgagaggtat cgattaccac ataaataatt taccgcgtca
      661 gcatcatcta aatatagttc tgcataataa cgatatgttt ttctgcatag ttctggcgat
      721 acgtttttat atactgtaat tttgctcaaa atttggcgaa tagtccgagg agaaatttgc
      781 tgatcatgtg aggaacgaaa aacaaaagaa ttttcgtccg tattttgtgc tgttaactta
      841 aaatagttct ccagaaatgg catcgcttct tttggtattg gtactttatt cagtctgttt
      901 tcttttctat tcagattaag aatctgcttg gtcaaagata catctttacg tttaagttct
      961 actacttcat ggatctttaa tccgcaatac agaagaatgg cagtaattgc aaggttcctc
     1021 ggtctattct tttcttcaaa gctagcttct ctgcttgttt gaaagccttc aatcgggata
     1081 aacaaatgct caaaatcttt gaaaagttct gcatcgatat atcgcggagc tgctttggtt
     1141 gtttccggta aacttgtacc caaaagagaa atctcttctt caatcagtcc tttttgatac
     1201 aaaaatcgta aaaaatgatt taatgaatat tgcttccttg aaatcccgta atagctattt
     1261 tcaaacaatt gctccgtttc ttggttcgct gtagtttgga acgaacgagt atgtcgatag
     1321 attttagcta agaaattctg ataatcttgt ttttctaaat ggataatcag ctgatcatcc
     1381 acttcttcag aaaatacttt tctcaaataa tcagtaaaca gatgaaaatc ttttgcgtat
     1441 tcatagcgac tgcctaatga aagggaagaa cgattttctt ctaaaaactg ttgaaagacg
     1501 gaagggagca agtgtgtacg ttgctttaac ttttcttgca gttgttttct agttttgctg
     1561 tccattacaa attccctcca atagtgttca ttttctatat tttaccgcat ttcatcaaat
     1621 gaagatagac agtttgtctt gatcttagga agcaaatttt taactaagta ctagctaaaa
     1681 gatatgaagt aagaagatac atttttagtt attttattag tgcagtcatt cttttgatct
     1741 tttaattgat ttatcctctt tttagctatg tggttacttc atgagcaatg aaatggattt
     1801 ggttcgttct aatggcagga ggctctttct tttatttccg aaaaattaga aaacattttt
     1861 tcagaatcga ttggctctcc atttattcaa taatggtttg tctaacgata ttgttgggat
     1921 aattcttaaa gaagtattag aaatagttgg tacttcatta ctttacatga agatttattc
     1981 tatggtagga gcaattatat tgagaattaa tcctttttta tataagttgt ttgcttatt
//
LOCUS       DAZKCH010000178         2009 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000178 DAZKCH010000000
VERSION     DAZKCH010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.186"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            100..570
                     /locus_tag="ACG84X_002853"
     CDS             100..570
                     /locus_tag="ACG84X_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFP9128647.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            792..1895
                     /locus_tag="ACG84X_002854"
     CDS             792..1895
                     /locus_tag="ACG84X_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFP9128648.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          684 a          326 c          460 g          539 t
ORIGIN      
        1 gaatctctga agaataaatc acgtgatcgt gacgataaaa tacacttacg tcaggtgata
       61 aaaaatacat aagtagaaaa ctaagaggag gaacagaaaa tgaaagaagt tcaattgatc
      121 agaaaaagcg aactatcaga aggtggttgc aatgcatgcg gcgtagtaga agcaacaagc
      181 tatacattaa agcttggtgc caacaaagcg ataatctctg agttgacagt aggcggtctt
      241 gtggacagtc tggcgcttgc tgaaggtttt attggagaag atatttatga gatgttttca
      301 gaaatccgtc agttaaaaaa aggggaaaac tgcatagagg ttcatcatga gagcccgaat
      361 gtgagattca aacgtggtga taatgagatg atcttcaata atcatgtgtc cgatcacacc
      421 gagctatatg gaatcgtgaa tcaaatacta actgagcttt ttggattggg accttatgcg
      481 ttcaaggaag aaaacggtaa tccaaaatta aacgaagaat ggcaagaaac gattgaaata
      541 caaagaaaca acccgcactt atttcaatag gcatccacag tatttcgtaa aagggacttt
      601 gacacgactt ttgtcaaaat cccatcgttt tttatctatt tgtgttctaa acatttcttt
      661 cagagtagta acaactggaa tgactgaaat gtaaacagat tatttgcctg tatcaatacg
      721 gaagagtaat ataaagtgtg taaacgctat catattattc attcaatttt ttatagaggg
      781 aaggcattga aatggaaaaa acgtatcaag caggtacaaa tgaaggaata gtggatttta
      841 tcaatatgga agatttagaa atagccgctt cacaagtgat tccagctggt ggttatggtt
      901 acatcagcag tggtgctggc gacttattta cttatcaaga aaatgaacgg gcattcaatc
      961 atcagctgat tattcctcat gtattaagag atgtagaatt acccgataca actacacatt
     1021 ttgacaaaga aacgctgact gcaccaatca tcatggcacc agttgctgct catggcttag
     1081 ctcatgtgaa ggcggagaaa gcttctgcaa aaggtgtagc agattttggg acgatctata
     1141 cagcaagttc ttacgcttct tgtacattag aagagataag agaagcaggc ggggagaaag
     1201 caccgcaatg gtttcaattt tatatgagca aagatgatgg gatcaatttg gatattcttg
     1261 aagtggccaa gcgtaatgga gcaaaagcaa tcgtattgac agcggatgca acagttggcg
     1321 gaaaccgtga aacagaccgc agaaatgggt ttaccttccc actgccaatg ccgatcgttc
     1381 aggcttatca atcaggagta ggccaaacga tggatgctgt gtacaaatct tccaaacaga
     1441 agcttagtcc aaaagatgta gaatttattg ctgctcattc tgatttgcca gtctatgtga
     1501 aaggtgtcca gtcagaagaa gatgtctatc gttcattaga atctggtgct ggcggaatct
     1561 gggtatctaa tcatggtggc cgtcaactag atggtggtcc agcagcgttt gattcgttgc
     1621 aatatgtggc agaagcagta gataaacgtg taccaatcgt gtttgacagc ggtgtacgac
     1681 gcggacagca tgttttcaaa gcaatcgcat caggtgcaga tcttgttgct attggcagac
     1741 ccgttattta tggattgtct ttaggaggaa gtacaggagt ccatcaagtg tttgatttct
     1801 ttaaaacaga attggaaatg gtcatgcaat tagctggaac acaaacagta gaagatatca
     1861 aaaaaataaa attgcgtgag aatcgtttta tttaagaaac aaatgacgaa aaaaatagga
     1921 gtgcggcaga tgatgccgta ctcctatttt tatagttcaa ggatgtcact aatagaataa
     1981 tttgaaacga aaaaataaaa ttgaaatat
//
LOCUS       DAZKCH010000179         2003 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000179 DAZKCH010000000
VERSION     DAZKCH010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.187"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..378
                     /locus_tag="ACG84X_002855"
     CDS             <1..378
                     /locus_tag="ACG84X_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFP9128649.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /locus_tag="ACG84X_002856"
     CDS             426..1826
                     /locus_tag="ACG84X_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFP9128650.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
BASE COUNT          555 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tta
//
LOCUS       DAZKCH010000180         2000 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000180 DAZKCH010000000
VERSION     DAZKCH010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.188"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..194
                     /locus_tag="ACG84X_002857"
     CDS             <1..194
                     /locus_tag="ACG84X_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFP9128651.1"
                     /translation="FMKDKDASLVKVIAIMSVFFFVYNTTLRGETTGPLIYMILAMPE
                     VVKRKEHYYSEKNTKGEIL"
     gene            191..910
                     /locus_tag="ACG84X_002858"
     CDS             191..910
                     /locus_tag="ACG84X_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 32 protein"
                     /protein_id="HFP9128652.1"
                     /translation="MIPKKIHYCWFGGNPLPKKDRKCIESWKKYCPDYEIIEWNESNY
                     DLNKNRYMADAYKERKWGFVPDYARFDIIYNHGGFYLDTDVELIKSLDILRENHAYMG
                     FEGEIWVNGGIGFGAEEGHSVIKGLRDIYDSLSFYQNDGTLNLKPSPYYITDYLESIG
                     LVRDNSEQIINGLHIYPTDYFAAKDYDTGKIYKTSNTISIHQYNASWKTPKQKFVYRL
                     KSTIGQKKFNRLLALKKFLHL"
     gene            925..>2000
                     /locus_tag="ACG84X_002859"
     CDS             925..>2000
                     /locus_tag="ACG84X_002859"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFP9128653.1"
                     /translation="MKKICFISGVISRSGGTERVGSIIANSLSDLGYDVTILSFWNSG
                     EPYFGLDKTIKVDYMLNPKTEGKLYRTYLYPVWKLHKYICKNEFDIVIDIDTLLSLYT
                     TRAIKGTKCKLISWEHFNYWTMEMLKEKKRFKAKKLIKKYAKRLVVLTEEDRQKHIDE
                     YSLSEDFVITMPNPCISNIEYEYHYDKKRFLAVGRLVEEKNFADMISAWKIVEKKVDD
                     WDLIIVGKGELEKDLRQQIKDLNLQRVTIAGHSDHVEEYYKSASCYVLSSVYEGFPMV
                     ILEAQSYGLPVISYDCKTGPRDLVHHNFNGMLVEDKNIDQLAKSMIMFTKNTDLAMRM
                     SLNAYNNVQKFNLKEITKQWVALI"
BASE COUNT          729 a          219 c          408 g          644 t
ORIGIN      
        1 cttttatgaa ggataaagat gcaagtcttg ttaaagttat tgcaattatg tcggtattct
       61 tttttgtgta taacacaaca cttaggggtg aaacaacggg gccactgatt tatatgattt
      121 tagccatgcc tgaagttgtg aaaaggaaag agcattatta tagtgaaaaa aatacaaaag
      181 gagagatatt atgattccta agaagataca ttactgttgg ttcgggggaa atccacttcc
      241 gaaaaaagat agaaagtgca tagaaagctg gaaaaagtat tgccctgatt atgagattat
      301 tgaatggaat gaatcaaatt atgatttaaa taagaaccgt tatatggccg atgcatataa
      361 agaacgtaaa tggggttttg ttccagatta tgcaagattt gatattattt ataatcatgg
      421 tggattttat ttagatacag atgttgagct aattaagtcg ttagatatac ttcgtgaaaa
      481 tcatgcctat atgggatttg aaggggaaat ctgggttaat ggcggtattg gttttggtgc
      541 agaagaagga cattctgtta ttaaaggttt aagggatatt tacgattcat taagttttta
      601 tcaaaatgat ggtacattga acttgaaacc gagtccgtat tatattacag attatcttga
      661 atctattgga ttggttcgcg ataacagcga acaaataata aatggcctgc atatctatcc
      721 tacggattat tttgctgcca aggattatga tactggaaaa atttataaaa ctagtaatac
      781 aataagcatt catcaatata atgcatcttg gaaaacacct aaacaaaaat ttgtttatag
      841 attaaaatca acaattggac aaaaaaaatt taacaggtta cttgcactga aaaaattttt
      901 acacttataa aggagaaaag tactttgaag aaaatttgtt tcattagtgg tgtaatttct
      961 cgttctgggg gaactgaaag agtagggagt attattgcca atagcttgtc tgatttaggt
     1021 tatgatgtca ctattttaag cttttggaat agtggagagc cttattttgg gttagataag
     1081 acgattaagg ttgattatat gttaaatcct aaaacggagg gaaaattata tagaacttat
     1141 ttatatccgg tttggaaatt gcacaagtat atatgcaaaa atgaatttga tatagtaatt
     1201 gatattgata ctttgttgtc tttgtatact acaagggcaa ttaaaggaac aaagtgcaaa
     1261 ttgatttctt gggaacattt taattactgg acaatggaaa tgctgaaaga aaagaagaga
     1321 ttcaaggcta aaaaattgat aaaaaaatat gcaaagaggc ttgtggttct cacagaagaa
     1381 gatcgtcaaa aacatattga tgaatatagt ttatcagaag attttgttat aactatgcca
     1441 aatccgtgta tatctaatat cgagtacgaa tatcattatg ataaaaagag atttcttgca
     1501 gtagggcgat tagtggaaga gaaaaatttt gctgacatga taagtgcttg gaaaattgta
     1561 gaaaaaaaag tagatgattg ggatcttatc attgtaggaa aaggtgaatt agaaaaagat
     1621 cttcgccagc agataaaaga tttaaatctg caaagagtaa ctatagcagg gcattcagac
     1681 catgtggagg aatattataa atctgcatct tgttatgtgc ttagttctgt ttatgaagga
     1741 tttcctatgg ttatattaga agcacagtct tatggattac cagttatttc ttatgattgt
     1801 aaaactggtc cgagagattt ggtacatcat aattttaatg ggatgttggt tgaagataag
     1861 aatatagacc aattagctaa gagcatgata atgtttacta agaatactga tttagcaatg
     1921 agaatgtcac tgaacgcata taataatgta caaaaattta atttgaaaga aattacaaaa
     1981 caatgggttg ctttgattga
//
LOCUS       DAZKCH010000181         1979 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000181 DAZKCH010000000
VERSION     DAZKCH010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.189"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(346..528)
                     /locus_tag="ACG84X_002860"
                     /pseudo
     CDS             complement(346..528)
                     /locus_tag="ACG84X_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(728..1744)
                     /locus_tag="ACG84X_002861"
     CDS             complement(728..1744)
                     /locus_tag="ACG84X_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFP9128654.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          556 a          460 c          310 g          653 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaacg ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaacgct ctccgaggga tttcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt catgcaaaat attcgcttat
      661 cgtgaattta cgtcactaaa cattgacgca aatccactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DAZKCH010000182         1926 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000182 DAZKCH010000000
VERSION     DAZKCH010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.190"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(204..449)
                     /locus_tag="ACG84X_002862"
     CDS             complement(204..449)
                     /locus_tag="ACG84X_002862"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128655.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(443..844)
                     /locus_tag="ACG84X_002863"
     CDS             complement(443..844)
                     /locus_tag="ACG84X_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFP9128656.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(1031..>1926)
                     /locus_tag="ACG84X_002864"
     CDS             complement(1031..>1926)
                     /locus_tag="ACG84X_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HFP9128657.1"
                     /translation="VNGRGLNEAVNIKDFNLMKWIGANSFRTSHYPYSEEIMRLADRE
                     GIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKTVIKELIERDKNHPSV
                     VMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYLKSTPDVCKVGDIVDV
                     LCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTEYGADTVAGFHDTVPT
                     MFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILRVQGNKKGIFTRDRKP
                     KMIAYYLQKRWSSIPNFSYKK"
BASE COUNT          609 a          368 c          250 g          699 t
ORIGIN      
        1 aattatttta gaatatttat cgctccttct ttacagcaag aaatcatggc gcaactaaaa
       61 tatgctcctt aaagtgttaa cgtactgata gaatctattt aattttcaat gaacaatagg
      121 ttttctacct aaaagaatct actaattcct taactattag aagattcttt taaacagaaa
      181 aagtggaaag gggatttttt taattagtta attttaaatt ttaagatcgc ttctattaat
      241 ttaatttcta gctgacttat catatattca tctacatagg taacgaattg acctacctcg
      301 ttaaatccat ttgtcaaaca taacttagcc atataagaat gataatgttt gagtatcatc
      361 ttgatcgaaa ttggatctcc ttctagagca gataagataa tggatagtgg aactaatagg
      421 tactgccgct ttttagattt atctaccata ggtcataccc cattttcaat tgttcaactg
      481 ccttctttcg ttgataccag ataccacttg tgctcatatt gagaatttta ccgatttcag
      541 catcattaaa acctgcaaaa taataaagta ggataatctt tcttcttatc tccgataact
      601 gatcaattgc tgctgataac ttttgatctg aaattaatat ttccattcca aataagaaat
      661 agacatcttg ttcatcaaaa tgagtttggg aatacctgcc ttcatttgaa tctgccaatg
      721 gttcctcatt atcctttatg ttagcgtttc gttttcgaat agacttagct tcgtttcgta
      781 atactttttt acagtaggca tcaaattggt gttgtataga tatgtcattg taatgttgtt
      841 gcatgataat atgctccttt ttcccccttt ccactaatac aacaatcaga aagccccttt
      901 ttttcgaaaa aactagaaaa aaaacataaa aatatttatc attctttaaa cagaaaatct
      961 ttctataaaa aacaaaaaaa aacgattagg ctaggctaat cgttttttga acattcttaa
     1021 aaaatccaaa ttatttttta taactgaaat tgggtattga tgaccatcgt ttctgtagat
     1081 agtaagcaat cattttaggt tttctatctc tagtaaagat tcctttctta tttccttgca
     1141 ctcttaaaat cccttgactt gttgcaaaat ctgcaaaatt ccacacttgt tcaccaacaa
     1201 aattttcaca tgtatctatt acttcgtgat ttgcttcgta ataagccact tgatactctt
     1261 ctgtaaacat tgttggtact gtatcatgaa atccagctac tgtatctgct ccatattctg
     1321 taaacattat tggcgtatca ggacatcttt ccatccatcc atctagctct tttttcaaca
     1381 gatattttgc atgtgccaga tcccctcccg aaacatacca accataataa cgatttaaac
     1441 ataaaacatc gacaatatct cctaccttac aaacatctgg cgttgatttt agataagtaa
     1501 cgattgttac aggtcttttc tgcggatcaa gttctttagt taattcaact aaaggttcaa
     1561 aatattcttt agcaccttcg gaatccgaat ctggttcatt tgcaatagac cacattacaa
     1621 cacttgggtg gttcttgtcg cgttctatca attccttgat caccgtttta tgagaatttt
     1681 ctgttcgtat ctctttccac gtattatgtt tttccacatt atcatctaat aaagtggcca
     1741 tgaaatttaa atgtaaccct actgcaggta cttcatcaat aactacaata ccttctcgat
     1801 ctgctaatcg cataatttct tctgagtaag gataatgtga tgttctaaaa gaattagcac
     1861 ctatccattt cattaaatta aaatctttaa tatttacagc ctcattcaaa ccacgtccat
     1921 taacat
//
LOCUS       DAZKCH010000183         1922 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000183 DAZKCH010000000
VERSION     DAZKCH010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1922
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.191"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            273..839
                     /gene="amaP"
                     /locus_tag="ACG84X_002865"
     CDS             273..839
                     /gene="amaP"
                     /locus_tag="ACG84X_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFP9128658.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            852..1040
                     /locus_tag="ACG84X_002866"
     CDS             852..1040
                     /locus_tag="ACG84X_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFP9128659.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1053..1610
                     /locus_tag="ACG84X_002867"
     CDS             1053..1610
                     /locus_tag="ACG84X_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFP9128660.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1642..1884
                     /locus_tag="ACG84X_002868"
     CDS             1642..1884
                     /locus_tag="ACG84X_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFP9128661.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          708 a          296 c          395 g          523 t
ORIGIN      
        1 aataaataga atcttgtaat aataactgag cataatcttt gcaattttta atcttgaata
       61 atatccttta agtatagcca gcaatcaaaa gtaaatagag aataagtaag caattgttat
      121 ttcagtatca gactggcaat aaaacgccgt tatgatccag caatgtttgg tagcgcttta
      181 tttactgatg ctatgctaac tgttcgctat ctatactgtg attgtcggta gagttattta
      241 cagggtaaaa ataagtttat aggaggtgga aaatgaataa ggggttaaaa ataatcggtg
      301 ttatcatgag tttactgcta ctttcagtat ttctagcgat tgcgttgatc aatgcgccgt
      361 atattatgcc tgaacaattg gaacgatttc gcttctttac tttaacgaat tactacatgc
      421 aacaatatat tttctgggca gctgtagtat ttgccgttct tgctattatc atcttgctag
      481 tcgttctttt ctatccaaag tcaagaggaa ctttcgttat gaaacgggaa gatggcaaac
      541 taacaatcga caaaaaagcg atcgaagggt tggtacgttc ccatttacac gaagaagagt
      601 tcattcattc acctaaagta cggatacgtt caacgaaaaa tcgaatccat atccatgtca
      661 acggagactt gaaacgaact tcttcattag tagggaaaac aggtgtattg atgcaagata
      721 tcgaagaaga agtaactaaa gtactcggaa caaaagaaac ggtcaaagtg gcagtcacat
      781 acagcggtta tgaagaacaa gaagatacaa gagactacaa gcactctcga gtggaatagg
      841 agggccaaat aatgaaagaa ctattttcag catacaagct ccctattatc tttgggggtc
      901 ttggactact gctagctgtt ttatggttaa cgattggatt tttcaagaca ttgttgatca
      961 taatcatgac agcaattggc gcaggaatcg gtttttattt gaaacagtca ggaatagttg
     1021 atcaattttt taaatcatag gaggaaacaa agatggaaaa caaaaacatg aatacaacaa
     1081 atggatcagt tttggcaaat gaaaaaggag aaaaccgcat gatgaatggt gaattgactt
     1141 atgaagacaa agtcatccaa aaaatcatcg gttatgcatt gaaagatgta gatggtctat
     1201 tgacattaga tggcggattt ttctcaaata tggctgaaaa attagtcaac acagataacg
     1261 taacagcagg tatcaataca gaagtaggta agaaacaagt agctgtggat ctagatgtga
     1321 tcgtagaata cggtaaagac atcgaagata tttacaacca aatcaaagaa ttgatcagta
     1381 ctgaagtaaa caatatgaca catttagatg ttatcgaagt gaatgtgaat gttgcagaca
     1441 tcaaaacaca agaagaatac caaaaagatc aagaaacagt acaagacaaa gtaacagaag
     1501 cagcaaaatc cacaggacaa tttgcttcac gccaaacaga taaagcaaaa tctgctgtag
     1561 gcaaaggtgc acaaaaagtc aaagaaaata acgaaccacg tgtacaataa gaagtaagaa
     1621 gtcagttagg aggaatttaa aatgggattt atttgggcat taatcgtcgg cggtatcatt
     1681 ggagcaattg caggagcaat cacgaataaa ggatcatcaa tggggatcat cgcaaacatc
     1741 attgctggtt tagtaggttc agcaattgga caagctttac taggaacttg gggaccaaca
     1801 attgcaggaa tggctatcat tccatcattg atcggtgcaa tcattttagt attagtcgtt
     1861 tcattctttg cacgtaaatt ataagcaaat tgaagaaaaa cttatgttga aatgaagaac
     1921 aa
//
LOCUS       DAZKCH010000184         1920 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000184 DAZKCH010000000
VERSION     DAZKCH010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1920
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.192"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..86
                     /locus_tag="ACG84X_002869"
     CDS             <1..86
                     /locus_tag="ACG84X_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFP9128662.1"
                     /translation="LYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            83..>1920
                     /locus_tag="ACG84X_002870"
     CDS             83..>1920
                     /locus_tag="ACG84X_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFP9128663.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT          717 a          234 c          384 g          585 t
ORIGIN      
        1 ttttatatcc tggaaaaaat gaaattaaat ggacgaaaaa tattcattca tttgaaataa
       61 tgcctaggtg gtggagaaaa gtatgaaacc aagaatatat agtcctactg aaacagattt
      121 ctcaacgaat ggcttaggaa ttttaaagga ttgtacaaga tgtggaatat atgaagtagc
      181 taatggaaaa tatgaattag agttggatta tcctttagga actagatttg atgaatattt
      241 tgaaaatgac tatcaaataa aagcaaagcc aaacgatcaa gaagagtatc atatcttttt
      301 tattgatgat aaagatatag atactttttt aaatacagta actatttatg ctcagagtcg
      361 tacaaatcga cttggaagac gggtagtcac tcttgtggaa gtggactcta aaactggtca
      421 agaagcgata tcaattattg aaactaaaat ggataaaaaa tctgacatac gactttattc
      481 tgatattacg gctgtttcta gcacaatctt tgaagcgaga aatgttttaa attgtattgc
      541 tggtgaacaa ggatcattgc ttcaatattg gggcggagaa attaaacgtg aaccatttaa
      601 gctttctttg ttaaagcgaa gaggtcgcaa taatgttgga acgattcggt atggaaaaga
      661 tatgtctggt ttgaaggtca aattagattg gacaggtata aaaacaagaa ttattccata
      721 tgctgatcct caaagtgaag taggtacgac taatcgaatt tatggttcgc cagtagatag
      781 tgcctatatt aataactatc ctgatgtcta tacagaacat gttcagttta cagaagaaca
      841 aggagtaaaa gacattaaga gcttaaataa aatagctaaa aattacttta aaacgatcaa
      901 tcctggctgt gataagccta aagtttctat tacggttgaa tttgataagt tgactgatag
      961 tgaagaagcg aaagaatttg cgaagattag aaattatggt ctgtttgata catttaaaat
     1021 atatcataaa aaatataata tttatcttga atcaaaggtt agtggactac aatacgattc
     1081 tttatctgaa aaaactttga aattagaagc aggagacatt caagttgctt tttatcagca
     1141 acaagctgta actattcagg ataaattaaa agattatgca acgaataatt atatgagtga
     1201 ttttaatgat tatgtttctt caatgattac aggtcaaggc agtgcaggag gatatgtagt
     1261 tttatggcca aaagaaaaac cttccaacat ctttattatg gataatccag atttagaaaa
     1321 ggcaagagaa gtactaagaa tgaataaaaa tgggattgct ttttctaaga aaggatggcg
     1381 ggggcctttt aattcagctt ggacattaga tagtatattt aatgccaatt ttatacaaac
     1441 tggattaatc aaagcagata tctttcaaaa ttcttttaac aagactggag atgtattgaa
     1501 attagttaat ggactactcc aaatttggaa caacaaaaag aaaataatgg agttaactaa
     1561 aaaaggaatg gaattttgga attctaaggg ttcaattgga acgattggaa caactgattc
     1621 tgttggtaat ccttttcctg gggcttctac tccaacccct attgaagata attctttagt
     1681 tattcgtaca aatggagacg gcaaatatat tttgatttct cctaaagtag gaaaaggatt
     1741 agttttatta ggaaatggta aagcaattta ttttggagac ttagatgtac aaggaaaact
     1801 tacagttaaa ggaaaagaaa taattcctgg acaaggtggt ggtccatcgg gaggtggaga
     1861 atctactggt gggtatccta gtgaattaaa aacagatgca gaaaagagag cttggagaat
//
LOCUS       DAZKCH010000185         1860 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000185 DAZKCH010000000
VERSION     DAZKCH010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.193"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..189
                     /locus_tag="ACG84X_002871"
     CDS             <1..189
                     /locus_tag="ACG84X_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9128664.1"
                     /translation="NSNGILRRNGLPKSIDFREVNQTFISSVSNQRNHIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
     gene            complement(1055..1585)
                     /locus_tag="ACG84X_002872"
     CDS             complement(1055..1585)
                     /locus_tag="ACG84X_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HFP9128665.1"
                     /translation="MRLGLIIKNILNLPKTIYFNYKFLHISDAWRLPILVHRKVRITR
                     KSRGKIEIVLQSGKIVYLGFPVLNTAGNEETIISIEGILRIQGPAFIAQGAHIDIRKN
                     AVLDIGSKFNSTGKMSIICFKEIQFKDGCTVSWDTLFMDTDSHTIFELNTHRILNKNN
                     KIVIGKHCWIGAKSVI"
     gene            complement(1582..>1860)
                     /locus_tag="ACG84X_002873"
     CDS             complement(1582..>1860)
                     /locus_tag="ACG84X_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9128666.1"
                     /translation="STACLENIILFIPYVYMVMSIKYENIKKPKIWSSIVYGGKIAFY
                     FSAIIEFLQLFLRLGTFQISDFVYNTLGGILGVILYKLILITKRDGER"
BASE COUNT          599 a          359 c          219 g          683 t
ORIGIN      
        1 aattctaacg ggattctgcg tcgtaatgga ctgccgaaat caatagattt tagagaagtg
       61 aatcagacat ttatttccag tgtcagcaat caacgcaatc atattccaag aaaatcattg
      121 aattacagaa caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc
      181 ttaatttgac aaatcatata atttaaaatt aacattgatt ctcctatgaa aatatctttt
      241 acctttctcc tgtgaaaagg aaatttcctt ttttatagtg ttattgatat aatcagaata
      301 ttcatcaaac tctgtatctg gagttaaaaa tctacagtaa catctataag ctttgctagt
      361 aatcttcttg ggttctctct ccattgtcaa gcaacatcaa aacacctact tactattcga
      421 ttcttttctg ccaaaaacga gtcagcatca ctcacaactt atgtgttgct gactccgact
      481 agtcctttgt tcaatatcaa cttattaaac agatataata tttttcttta tttcgtatac
      541 tccaagactt ccatctttct ttcatcttat ctctgaaaaa aacacagcaa agtgccctta
      601 ataaatatac attagaattt gcaaattttt tcatcttaag atatatccta ttcatattct
      661 ttacaatcct aatgggtgat tacaaatcta tttagttcaa gttctacatt ataaacacct
      721 ttcttgatag tatcatctgc tgcacaagcg atgtcgatcc acttattagg ggatttacgt
      781 gctcaaaagt ggctattcct tttgggaagt ccatccataa taatggtcca tggatttttt
      841 tagggtcttg tcgttcaaat ttctcaaaaa ctttattata cttccatagt tttataatta
      901 tttggtttca ctttggctcg ttcaaacacc aacttgtatt tcttttcaac gttcgaactg
      961 gagccccccc tataatctca ttattatttt catgactttt tactaccgtg gaattacaag
     1021 caacaacaat attatctgct aaatgaacac ctttctatat cacgcttttt gctccaatcc
     1081 aacaatgttt acctataact attttattat ttttattcaa aatcctatga gtattcaatt
     1141 caaaaatcgt atgtgaatcg gtatccataa ataatgtatc ccacgatact gtacagccat
     1201 ctttgaattg aatttcctta aagcaaatta tactcatttt tcctgtcgaa ttaaactttg
     1261 acccaatatc taaaactgca tttttcctta tgtcaatatg agccccttgt gcgataaacg
     1321 ctggcccttg tattcttagt attccttcaa tacttataat cgtttcttca tttcccgcag
     1381 tatttaatac tggaaagccc aaataaacta tttttccaga ttgtaatact atctcaattt
     1441 tccctctcga tttgcgtgta atccgtactt tacgatgcac caaaataggt aatctccacg
     1501 catctgaaat atgaagaaat ttataattga agtatatcgt tttaggtaaa tttaatatat
     1561 tctttattat caatccgagt ctcatctttc accatctctt tttgtaatca aaattagttt
     1621 ataaaggatt acacccaata taccgcccaa cgtattatat acaaaatccg aaatttgaaa
     1681 cgttcctagc ctcaaaaaaa gttgtaaaaa ttcaattatt gctgaaaaat aaaatgcaat
     1741 ttttcctcca tatactattg aggaccatat tttgggtttc tttatatttt catatttaat
     1801 agacattacc atataaacat atggaataaa aagaataata ttttctaaac acgctgtaga
//
LOCUS       DAZKCH010000186         1852 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000186 DAZKCH010000000
VERSION     DAZKCH010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.194"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            29..1174
                     /gene="tgt"
                     /locus_tag="ACG84X_002874"
     CDS             29..1174
                     /gene="tgt"
                     /locus_tag="ACG84X_002874"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFP9128667.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            1271..1651
                     /gene="yajC"
                     /locus_tag="ACG84X_002875"
     CDS             1271..1651
                     /gene="yajC"
                     /locus_tag="ACG84X_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFP9128668.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
BASE COUNT          639 a          312 c          392 g          509 t
ORIGIN      
        1 atattttata tagaaagtag ggaaatgaat gacgcaacct gccattcgct atcgtttaat
       61 caagaaagaa aaacatactg gcgcgcgttt aggggaattg atcacgccac acggaacttt
      121 ccccacacca atgttcatgc cagtaggaac attagctaca gtaaaaacaa tgtccccaga
      181 agagttgaaa gaaatgggtg ctggcgttat tttaagtaat acatatcatt tatggctacg
      241 ccctggtgaa gacttagtag aagaagctgg cggactgcat aaatttatga actgggatca
      301 accgatttta acagattcag gcggctttca agttttttca ttaagtgata tgcggaatat
      361 cgaagaagaa ggcgtgcatt tcaaaaatca cttgaacggt tcgcgtatgt ttttatcacc
      421 agaaaaagca atcaacatcc aaaataaatt gggctctgat atcatgatga gttttgacga
      481 atgtccacca ttcgatgaaa gttacgacta cgtgaaaaaa tcagtagaac gtacgtctcg
      541 atgggcagaa cgaggattga aagctcatgc taatccagac cgtcaaggat tatttggaat
      601 catccaagga gcagggtttg aagatcttcg tcgtcaaagc gcgaaagatc tagtcgggat
      661 ggatttccct ggttactcaa tcggcgggtt atctgtcggg gaacctaaat cagaaatgaa
      721 tcgtgtatta gaattcacta caccgttgat ccccgaaaac aaaccacgtt acttgatggg
      781 tgtcggtgct gctgattcat tgatcgatgg tgttatccgt ggagtagaca tgtttgactg
      841 tgtcttgcct actcgaatcg ctcgaaatgg cacatgtatg acttctcaag gccgtctagt
      901 agtgaaaaat gcgaaatatg cccatgattt ccgtccaatt gatgagaaat gtgattgtta
      961 tacatgtaaa aactatacac gtgcctatat ccgccatttg atcaaatgtg atgaaacatt
     1021 tgggattcgt ttgacttctt accacaattt atacttcttg ttgaatctaa tgaaacaagt
     1081 acgtcaagca atcatggatg ataatttgct tgaatttaga gaagcctttt ttgaagaata
     1141 cgggttcaat aaagaaaacg caaaaagctt ctaaaggaaa atcttttaaa aattaagtaa
     1201 aaaactagtg ttatcagcat ttttctgcta aagtgttttt tgtagataca gaattagtga
     1261 ggtgaaaaaa atgggaacat taccaatgct tgtgatgttt atcgcgctat tagcaatgtg
     1321 gttttttatg tcacgttcgc aaaagaaaca acagcaagaa cgtcaaaact tgttagatag
     1381 catgaaacca ggtgattcag tcgtaacgat cggcggatta catggagttg tttcagaaat
     1441 cgacaatgac aaacggacag ttgttttaga ctgcgaaggg atcttccttg agtacgatcg
     1501 tgcagcaatc aaaacggtca aaccagggac tgtcgtaaca aatgatgcaa cgactactgt
     1561 tgaaacaaca gaagaaccag ctgagacagt tgaagtaaaa actgaaacaa cagaaacgct
     1621 ggaagagaca gaagagaagg aagaaaaata agtatcaaag cttatttaaa gacgaggtag
     1681 ggcagaaaga tgtcctacct cattttttat tcaaaaaaga aagagataag agcatgggat
     1741 atattgctca atattgaata atcgggtgtg tcatataaat aataataaat aactttatat
     1801 atttttctat acaaacacct gtaaataaag caattttata tttaaaaata ac
//
LOCUS       DAZKCH010000187         1731 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000187 DAZKCH010000000
VERSION     DAZKCH010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.195"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..156
                     /locus_tag="ACG84X_002876"
     CDS             <1..156
                     /locus_tag="ACG84X_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HFP9128669.1"
                     /translation="GTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAIS
                     SIVIPPK"
     gene            169..1077
                     /locus_tag="ACG84X_002877"
     CDS             169..1077
                     /locus_tag="ACG84X_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFP9128670.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1077..1697
                     /locus_tag="ACG84X_002878"
     CDS             1077..1697
                     /locus_tag="ACG84X_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128671.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          613 a          251 c          395 g          472 t
ORIGIN      
        1 ggaacttatg gacatactgg cgttatccga ggcttagcta atggtcgtat gcaaacttat
       61 gaacaaaaca cagagttagg tatgatttgt ggaaagttag atcgccagta ttatagtgca
      121 agtgcaattt cttccattgt cataccacca aaatagggag gtgatttaat ggcaaagtgg
      181 aatgtcatat taagtacaac agaaccctat aattacgtgg ggatgattca agttcgacaa
      241 ggcaataaga atacagaggt tatggaagcg actatagttg aaaatggtct tccctacgat
      301 ttatcagaat gtaaggtata ttttgaatca gttgtaggtg ggaaatatcc agtccaatta
      361 gaaacaaaaa ttgtggatgc taaaaaaggg aaaattaact atatttttga taaatattcc
      421 atgcagtgtt tacatcgaca aacagccaat ttcattatat ttaaaggaga agacttgatt
      481 ggaacaactc aagacttctc ttattttgtc attaatgctg tttcaaaaac agaaggagaa
      541 atgggttctt attggcaatc aatcgaagat ttaattgcgg atatgacgga ctttattaat
      601 gaaaataaag gcgattttac ggactggatg aatgaaagga aagaagaatt tgaacgttgg
      661 agacaagaac aggaacacag tttccaagat tggagagaag gacaagaatc agactatttg
      721 gcatggtttg aatcaatcaa ggatatttta aagacgattg atccaggtgg agtcatgtta
      781 gccgaactaa cggatgcgcg agtagatatt caaggagttc gtcatgcgtc tatttcagag
      841 cgtttgctgg cagatatgga ctatttatat cagaaattgc gagcaacgct tttcacgatt
      901 gaatacgggg agattgaagt gactgatatt ttgcaggatg atctcttttc agataatcat
      961 gaagtcgaaa aagttggaac tgtagcattc ccgattgaag aaggagcctt gatcatcgca
     1021 accgttgatg atccaaagca aaatgtgttc actcttgaga aagttggggt gatctaatgg
     1081 ctaaaactaa acgaatgatg gaaacggatg aaaaaacggg tgtacaacgc caattctttc
     1141 caatcacaca tgcttccgca gttcttgggt tagaagaaat aatagcagga gaagcaacag
     1201 ttttatctgt taatggaaaa attggagccg tcgtcattac taaagaagat ttgggattag
     1261 agaatgttct cacagaatta ccctatgcaa gtgaagaaga tgacggcatt atcacggcag
     1321 aaatgtatca aaaaatttta aacagtggag aaggtgacta cgtgttgcca gttgccacta
     1381 tcgaccgttt gggtggcata aaagttggtg aattattgac gattgatgag acagggaaag
     1441 tctctgcagt cagacaatct gatgtcaatt tttcgctgga gttaaaagaa aaactcgatt
     1501 cactgaaaaa ttatactgct ggagaaaaca tcactattga tgaagatgga acaattagtt
     1561 ctacaggtgg tagtgggact ggtggtgtca atcagtcata tgtagatcaa aaattccaag
     1621 aagctgtaaa tcaagcagaa aattacacaa acgaaagaat tccaaatttt acttttgaaa
     1681 aaattgggga ggtatagaga atgacagata tcgtaaaaat aaaacaaagc a
//
LOCUS       DAZKCH010000188         1716 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000188 DAZKCH010000000
VERSION     DAZKCH010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.196"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            75..812
                     /gene="erm(B)"
                     /locus_tag="ACG84X_002879"
     CDS             75..812
                     /gene="erm(B)"
                     /locus_tag="ACG84X_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFP9128672.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            982..1242
                     /locus_tag="ACG84X_002880"
                     /pseudo
     CDS             982..1242
                     /locus_tag="ACG84X_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1376..1615
                     /locus_tag="ACG84X_002881"
     CDS             1376..1615
                     /locus_tag="ACG84X_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFP9128673.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
BASE COUNT          670 a          259 c          301 g          486 t
ORIGIN      
        1 gataactaaa attacaaaca aatcgtttaa cttctgtatt tgtttataga tgtaatcact
       61 tcaggagaga ttacatgaac aaaaatataa aatattctca aaacttttta acgagtgaaa
      121 aagtactcaa ccaaataata aaacaattga atttaaaaga aaccgatacc gtttacgaaa
      181 ttggaacagg taaagggcat ttaacgacga aactggctaa aataagtaaa caggtaacgt
      241 ctattgaatt agacagtcat ctattcaact tatcgtcaga aaaattaaaa ctgaatactc
      301 gtgtcacttt aattcaccaa gatattctac agtttcaatt ccctaacaaa cagaggtata
      361 aaattgttgg gaatattcct taccatttaa gcacacaaat tattaaaaaa gtggtttttg
      421 aaagccgtgc gtctgacatc tatctgattg ttgaagaagg attctacaag cgtaccttgg
      481 atattcaccg aacactaggg ttgctcttgc acactcaagt ctcgattcag caattgctta
      541 agctgccagc ggaatgcttt catcctaaac caaaagtaaa cagtgtctta ataaaactta
      601 cccgccatac cacagatgtt ccagataaat attggaagct atatacgtac tttgtttcaa
      661 aatgggtcaa tcgagaatat cgtcaactgt ttactaaaaa tcagtttcat caagcaatga
      721 aacacgccaa agtaaacaat ttaagtacca ttacttatga gcaagtattg tctattttta
      781 atagttatct attatttaac gggaggaaat aattctatga gtcgcttttt taaatttgga
      841 aagttacacg ttactaaagg gaatggagat aaattattag atatactact gacagcttcc
      901 aagaagctaa agaggtccct agcgcctacg gggaatttgt atcgataagg ggtacaaatt
      961 cccactaagc gctcgggacc ccttgtagga aaatgtccta agtgtggcaa caatattgta
     1021 ttaaaaaaat cgttttatgg ttgttcaaat tatcctgaat gtaagtttac tttagctgaa
     1081 cattttagaa agaaaaaact aaccaaaacg aatgtaaaag aattactgga gggaaaagaa
     1141 accctggtaa aaggaatcaa aaacaaagag aaaaagccct acaatgccgt tgtaaaaatt
     1201 ggggaaaagg gatatattga ttttatatct ttctcaaaat aaacataaaa gccctttaaa
     1261 gagggctttt atatattaat cacaaatcac ttatcacaaa tcacttatca caaatcacaa
     1321 gtgatttgtg attgttgatg ataaaataag aataagaaga aatagaaaga agtgagtgat
     1381 tgtgggaaat ttaggcgcac aaaaagaaaa acgaaatgat acaccaatca gtgcaaaaaa
     1441 agatataatg ggagataaga cggttcgtgt tcgtgctgac ttgcaccata tcataaaaat
     1501 cgaaacagca aagaatggcg gaaacgtaaa agaagttatg gaaataagac ttagaagcaa
     1561 acttaagagt gtgttgatag tgcattatct taaaattttg tataatagga attgaagtta
     1621 aattagatgc taaaaatttg taattaagaa ggagggattc gtcatgttgg tattccaaat
     1681 gcgtaatgta gataaaacat ctactgtttt gaaaca
//
LOCUS       DAZKCH010000189         1685 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000189 DAZKCH010000000
VERSION     DAZKCH010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.197"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..182)
                     /locus_tag="ACG84X_002882"
     CDS             complement(<1..182)
                     /locus_tag="ACG84X_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFP9128674.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="ACG84X_002883"
     CDS             517..951
                     /locus_tag="ACG84X_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFP9128675.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="ACG84X_002884"
     CDS             974..1294
                     /locus_tag="ACG84X_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128676.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="ACG84X_002885"
     CDS             1435..1626
                     /locus_tag="ACG84X_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128677.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
BASE COUNT          637 a          254 c          356 g          438 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaac
//
LOCUS       DAZKCH010000190         1636 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000190 DAZKCH010000000
VERSION     DAZKCH010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.198"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(183..1502)
                     /locus_tag="ACG84X_002886"
     CDS             complement(183..1502)
                     /locus_tag="ACG84X_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFP9128678.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT          485 a          301 c          325 g          525 t
ORIGIN      
        1 attctttggc acattttatt gaaatatgta tcactaatat ccctatcaac tgattttgac
       61 taaaaagtta cttcaaacat tcactgttca aaaatattga ggaataaatt ttgggtgtaa
      121 ggcattttga gcatacttct ccctggataa cttcccagta aaaaaatcgt tagattgttg
      181 gattagatcc attgactggc tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga
      241 tacacatgat aactagataa tttgagatag actcgtctac ccgtttggac taatttccca
      301 gcaactttca gaaacttcaa tcgaatagaa tgaatggtca ttcccttttg gacttcttca
      361 aagccaatcg ttcttaagaa gttgactaag ttgtaagcta tcaagctgag catcattcgg
      421 acatgattct ccaaaaagcg aggactgtct gttttgtcaa agtaaaagcc agctttcgct
      481 tctttaatga agttctccat tgtgccacgt ttggcataga tagaaaagat ggtatcagga
      541 gaaacatttt ctgatagatt cgtcacgata aattcatgtc gaaagagtag ttcgcccgct
      601 tcacgtgttg agcgtataca cacgcgacga ctttgtgacc aggattgtgc ttgataagtg
      661 gtcgagaagt actgaacttc tcgttcttcc cacttttgat tatcgccata aagtactgat
      721 ttctcagcta tttgacctag tctacgatta ttcttcagtc gaataacata atgactcttt
      781 tttgattcac acgaatcata cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag
      841 atgtcagtgt ttggtagaga gtgattatag tgctctaata aaggtgtgag aaactccttt
      901 acgccttttg atgtatattg atttcctgaa cgtagttcag cttttaagaa gtcaccagtc
      961 aatccgtcaa aagctaccaa tggatggtaa ccataggttt ggtagtgtgt attataattc
     1021 gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc
     1081 gtatcattac ggatgaggcg tgctttatcg ataagttctt ggttcaaagc ttgaagttca
     1141 tggatattct cctcagatag tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt
     1201 tctttcctat ctaaaacagc tttaaacaca ggatcttgtc tcaggagatt agctgcagaa
     1261 tcagctgagt aaccagcaat taattgcata atgaactgct caagtatgga taagttgtca
     1321 tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa
     1381 ccaaagatgt tcatcagctc tttcactagg acgagacccg aatcactcga taattgacca
     1441 cctgtatgag aaatagtgat atttgaattg aattttactt ggtttttgtg taagctagtc
     1501 atgaaaagaa ctcctttctt ttggttggtt tagtcacttt aaccatagca gaaaggggtt
     1561 cttttttcat cacttaacgg gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt
     1621 ttcacatggt tttaat
//
LOCUS       DAZKCH010000191         1615 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000191 DAZKCH010000000
VERSION     DAZKCH010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.199"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            370..702
                     /locus_tag="ACG84X_002887"
     CDS             370..702
                     /locus_tag="ACG84X_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9128679.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            612..806
                     /locus_tag="ACG84X_002888"
     CDS             612..806
                     /locus_tag="ACG84X_002888"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9128680.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            845..991
                     /locus_tag="ACG84X_002889"
     CDS             845..991
                     /locus_tag="ACG84X_002889"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128681.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            1429..>1615
                     /locus_tag="ACG84X_002890"
     CDS             1429..>1615
                     /locus_tag="ACG84X_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9128682.1"
                     /translation="MSYSEFTKELLDILDLNLIFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHRHYQNEQTIIK"
BASE COUNT          569 a          290 c          282 g          474 t
ORIGIN      
        1 attatcaacg ttttttaatt cgtttttagc ttaaaaataa cttttgtcac agtctcactc
       61 ctaaaattac tttatttacg tatgaagtgg gcaggaggtc gaatccagaa ctgggctatg
      121 gtacttcaac gaggacttct cctctagaat tgaaaagcat gcgatttacc ttccgtaacg
      181 acggtagatt tattcaacta tgtgtccaat caaaatttgt ctgatttcaa aaatagtcaa
      241 gagaattttg gttgttaaaa actcttatct atcaacttcc acagtttagt tgacaaaccc
      301 tgatactaag ttgggctatg atacactttt cttgactatc agttacgtta ccggaaggaa
      361 tgaactctat tgagaaaaac atatgatcgt aaatttaaac taaagatttc acaggatatc
      421 cttgagaaaa aagtaactac caagaaaatt gctgaagaat acaatatctc tcgtccaaca
      481 atttcccgat gggtttcaga atatcgtcga tacgggaaaa atgcttttgc tggacaagga
      541 aaaagattac ctgataaagc agatttctac attcttgaac aggaaaataa acgactaaaa
      601 gaggaagacg agtgttctac gaacacaaag atcgatacgg atctccaggg atcactcaaa
      661 aactttacga tgaaggaatc gaaatcaata aacgtgttgt agctgttctt atgcgtgaaa
      721 tgaatttatg cacaagagga tttcatcgac gcaaatcttc tcatggtaga gaaaaaacaa
      781 tcaaagaaat ggtaaaaaaa tgttgaatcg ataatttgaa cagaaccaaa ttgatgctgt
      841 ttgggtgatg gatattactt acattccatg taatgacggt cgcctctatt tgtccaccta
      901 tattgactta gcaactcgta ttctacgtta ctatatggta gattcacaca tgaaaaaaga
      961 gattgtcgtc cgtccattac aaatttatta aggagaattg cctacggtaa ttcattccga
     1021 tagaggtagc cagcatcggt cttttattta tcaagagctg ttgaacgacc accacatcac
     1081 acattcagtg agccaaactg ggactcctgt tgacaatgca gtaattgaag cgtttcatcg
     1141 atcaatcaaa tgagaattaa tcgactccaa caaatataaa agtaaaatag agatgaaggt
     1201 gttaatccaa gattatttag aagactacta cccaaacaaa agaatccata caaaatttat
     1261 gatgactcct tgacaatttg aagcgaagaa aataagggat ctataatatc tagtgttggt
     1321 gacgccttct gttgccaata ctttttcttt tttctaataa acgcaaacag acaccttaaa
     1381 atcctttaga ataaagtcga cgaaaaccat tcaaaggagt gtttcaagat gtcctattca
     1441 gagtttacca aagagttact agatattcta gacctaaatc ttatctttca tgaagatgcc
     1501 tttcgcaaag agcgaatcaa tgacgaaaca tgttttgttt ttgatggcac attgacctat
     1561 caaccggagg aatgctttca tcgccactat caaaatgaac aaacgatcat taaat
//
LOCUS       DAZKCH010000192         1563 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000192 DAZKCH010000000
VERSION     DAZKCH010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.200"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            47..1513
                     /locus_tag="ACG84X_002891"
     CDS             47..1513
                     /locus_tag="ACG84X_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFP9128683.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          432 a          290 c          329 g          512 t
ORIGIN      
        1 agatgtataa tattttctga aaatttaaag aattggggta tagattatgg aaaaacagca
       61 agacaagggc ttcttcgggc agccgaaggg attgtcaact ttgttcttca ctgagatgtg
      121 ggaacgattt agttattacg gtatgcgtgc attacttatc tattatatgt acgatacagt
      181 tgccaacggg ggacttggat taccacgagc aacagcatta gctatcatgt cgatctacgg
      241 atctttgatc tacatgtcta gtatcgtcgg cggatgggta tctgaccgag tgttaggagc
      301 aaaacgcact gtattcttcg gtggagtttt cattatgctt ggccacatcg tcttggcttt
      361 accatttggt gtaagtacat tgtttgtttc gatggcattg attattatcg gaaccgcctt
      421 tttgaaacca aatgtttctg gcatggtcgg acatctttat tcaaagactg acttgcgaag
      481 agatgcagga ttttcgattt tttacatggg tgtcaactta ggggcattat tagcaccact
      541 aatcgttggt acaatcggtc aagaatataa ctatcattta gggttctctt tagctgctat
      601 tgggatgttc tttggattat tacaatacat catccaagga cgcaagacat tagacggagt
      661 gggtacaaca ccgccgaatc ctttgacaac tgaagaacgt aaaggattca tccgtaactt
      721 gatcatcgca cttgttgtta tcgctgcagt attcggcggg gcacaactaa ctggtcatct
      781 gacaattgac ttttttgtca atacaatcag tgtattgggg attatcttac cgttgtatta
      841 ctttatcaaa atgctgactt caaaagatgt aactgctgaa gaaaaaccaa gagtatgggc
      901 ttatatccca ttattccttg cagcaatcat tttctggtca ttacaagaac aaggttcatc
      961 tatcttagct ttatttgcta gtgaacgtac acaatctacg ctatttggtg taacgatcca
     1021 agcaagctgg tatcaatcat tgaatccaat tttcatcttt attctgacac cagtattcgt
     1081 aacgatgtgg acgaaacttg gtgaacgtca accatctaca gtagtgaaat tctctcttgg
     1141 acttttattt gcaggattat cgtacttgct attgatgttg ccgggtatgc tttatggtac
     1201 aagtggaaaa gtaagtccat tgtggttgtt gggaagtttc ttcatcgtgg ttattgctga
     1261 attgtgtctt tcaccagttg gtttgtctgt gacaacaaaa ttagcaccac gagcatttga
     1321 atcacaaaca atcgctattt ggttcttagc tgatgcttct tcacaagcaa tcaatgcaca
     1381 aattgcacgc ttctacacac cgggaacaga atctgcttac ttcggtatta tcggtgcagt
     1441 agcaatcgtc ggtggtatct tgctatttac tgtgaaagaa ccaatcaaaa aactaatggg
     1501 ctctattcat taatcaatga acataaaaac aggaattgct tatttgcagc agttcctgtt
     1561 ttt
//
LOCUS       DAZKCH010000193         1560 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000193 DAZKCH010000000
VERSION     DAZKCH010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.201"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1473
                     /locus_tag="ACG84X_002892"
     CDS             <1..1473
                     /locus_tag="ACG84X_002892"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128684.1"
                     /translation="LRVQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAI
                     PKAGGMALFFPFISVMLLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLR
                     ENSEEFQETIELQQEINSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFS
                     YVSLAVVILVGVHLLLTGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQR
                     IRAMKETSIQEGSDSPLKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASG
                     SGKTSILKLVSRLYDYDEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENI
                     RIGNSQASDEEVKKAARLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFL
                     KNAPILILDEITASLDAENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQG
                     KLVDQGTHNELYRRSEIYKNLIKKTKLSEKFVYEKEAQSR"
BASE COUNT          535 a          229 c          294 g          502 t
ORIGIN      
        1 ttaagagtgc aaattgcaga cgatttgtca aatttaccat tatcctattt ttcaaaacat
       61 aatttatcag atttatctca aactatcatg tctgacgttg aaggtattga gcatgcgatg
      121 agtcatgcaa tacctaaagc cggcggtatg gctctgtttt tcccttttat ttcagtgatg
      181 cttttggttg gtaatgtcaa aatgggatta gctgttattt tgccaacgtt atttagtttt
      241 gtcttaatct tgttatcaaa gaaatcccaa acgaaagcca atactaaata ttacgatact
      301 ttgagagaaa actcggaaga atttcaagaa actatagaat tgcagcaaga gattaatagc
      361 tttaatctat ctaaaaaagt tcaagacaga cttttcaaaa aaatggaaga gagtgaaagg
      421 attcatttaa aggtagaatt aagtactttt tcagtcatgg ccttatcctc tattttctca
      481 tatgttagtt tagcagtagt cattctagta ggtgttcact tactgttaac gggtgaagtg
      541 actatactct acgtcgttgg ttacttacta gccgcaataa aaataaagga ttccttcgat
      601 tctatgaaag aagcagtgct tgaaatattt tatttagctc ctaaaataca gcgaattaga
      661 gctatgaagg aaaccagtat ccaagaggga tcagatagtc ctctgaaatc ttttgacatt
      721 gagttgcgag atgtctcttt ctcatatgat aacaataccc caattttaga tcatatctct
      781 tttacggcta aacaaggaga agtgactgcg ttagtaggtg ctagtggttc cgggaaaact
      841 agtatcttga aattagtgtc tagactgtat gattatgatg aaggctgtat tttaattgat
      901 gggtatgata ttaaacgtgt atctccagct tctttgttta gcaaaatcgc tattgttttt
      961 caagaggtaa ctttgtttaa tacaagtatt ttggaaaata tacgtattgg aaatagtcaa
     1021 gcgtcagatg aggaagtgaa aaaagcagct cgtttagcta actgcgaaga ctttattgaa
     1081 aaactacctg acggttatca tacattggtc ggagaaaacg gaagttcact ttctggagga
     1141 gagcgacaac gcctatccat agcacgggct tttttgaaaa atgcgccaat tttaatttta
     1201 gatgaaatta ctgccagttt agatgcggaa aatgaaaaac gtattcagga aagtttaaat
     1261 cgtttaatac aagataagac agtactaatt atatcgcatc gcttgaagtc tattgaaaag
     1321 gtaaataaaa ttgtagtgat ggatcaagga aaactagttg atcaaggtac tcataatgag
     1381 ttgtatcgaa ggtcagaaat atacaaaaat ctcataaaga aaactaaact atctgagaaa
     1441 ttcgtctatg aaaaagaagc tcaatcacga tgatgaaata ggctttaaat taacctacaa
     1501 tttttgggat atagttataa ttctttttca aaaagaataa ttttattaaa cagcatctaa
//
LOCUS       DAZKCH010000194         1536 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000194 DAZKCH010000000
VERSION     DAZKCH010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.202"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>1536)
                     /locus_tag="ACG84X_002893"
     rRNA            complement(<1..>1536)
                     /locus_tag="ACG84X_002893"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          321 a          476 c          337 g          402 t
ORIGIN      
        1 gggaaatctc atcttgaggt gggcttcaca cttagatgct ttcagcgttt atcccttccc
       61 tacatagcta cccagcaatg cccttggcag aacaactggt acaccagcgg taagtccatc
      121 ccggtcctct cgtactaagg acagctcctc tcaaatttcc aacgcccgcg acggataggg
      181 accgaactgt ctcacgacgt tctgaaccca gctcgcgtgc cgctttaatg ggcgaacagc
      241 ccaacccttg ggaccgacta cagccccagg atgcgacgag ccgacatcga ggtgccaaac
      301 ctccccgtcg atgtggactc ttgggggaga taagcctgtt atccccaggg tagcttttat
      361 ccgttgagcg atggcccttc catgcggaac caccggatca ctaagcccga ctttcgtccc
      421 tgctcgactt gttggtctcg cagtcaagct cccttctgcc tttacactct tcgaatgatt
      481 tccaaccatt ctgagggaac ctttgggcgc ctccgttacc ttttaggagg cgaccgcccc
      541 agtcaaactg cccatctgac actgtctccc accacgatta gtggtgcggg ttagagtggc
      601 cataacgcag gggtagtatc ccaccagcgc ctccatcgaa actagcgttc cgatttctac
      661 ggctcctacc tatcctgtac atgcggtaca gacactcaat atcaaactac agtaaagctc
      721 catggggtct ttccgtcctg tcgcgggtaa cctgcatctt cacaggtact aaaatttcac
      781 cgagtctctc gttgagacag tgcccaaatc gttacgcctt tcgtgcgggt cggaacttac
      841 ccgacaagga atttcgctac cttaggaccg ttatagttac ggccgccgtt tactggggct
      901 tcaattcgta ccttcgcttg cgctaagcac tcctcttaac cttccagcac cgggcaggcg
      961 tcagccccta tacttcatct tacgattttg cagagacctg tgtttttgat aaacagtcgc
     1021 ttgggcctat tcactgcggc tgatcgtatg atcagcaccc cttctcccga agttacgggg
     1081 tcattttgcc gagttcctta acgagagttc tctcgctcac cttaggattc tctcctcgac
     1141 tacctgtgtc ggtttgcggt acgggccgct gttttctcac tagaagcttt tctcggcagt
     1201 gtgacatcag gaacttcggt actattattt ccctccccat cacagcttgt ccttaagaaa
     1261 agaagcattt gactcctctt cagacttact gcttggacag acatttccga tcgtctgcat
     1321 tccttagcct cctgcgtccc tccattgctc aaacaaaaac aacgggtaca ggaatatcaa
     1381 cctgttatcc atcgcctacg cctgtcggcc tcggcttagg tcccgactaa ccctgggcgg
     1441 acgagccttc cccaggaaac cttagtcatt cggtggacag gattctcacc tgtctttcgc
     1501 tactcatacc ggcattctca cttctaagcg ctccag
//
LOCUS       DAZKCH010000195         1457 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000195 DAZKCH010000000
VERSION     DAZKCH010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.203"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(188..487)
                     /locus_tag="ACG84X_002894"
     CDS             complement(188..487)
                     /locus_tag="ACG84X_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFP9128685.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            838..>1457
                     /locus_tag="ACG84X_002895"
     CDS             838..>1457
                     /locus_tag="ACG84X_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFP9128686.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQ"
BASE COUNT          490 a          230 c          204 g          533 t
ORIGIN      
        1 cttttaatta acattattag tttatactag ctgtttttgt gttaattaaa ggataaaata
       61 caatataaag aaacatctgt ttctttattt agaataaaaa aatacagact ctgttcaaat
      121 aaatgaacct agcctgcatt atgagattga ctatactttt taattcattg agatgaataa
      181 ctcgttttta taaatgccca aaagtaatcg gtgccgaagc cattcctcga cctaattctt
      241 tttcaaattt tcctattgtt gatatctcca tataaaacgg tgatactggt ttagacaatt
      301 ctcccctgat tgctaacgga cgtaaactac gttccaaatt atttatgact ttaggataat
      361 actgaccttt ttctaagcct gtctttgcgt ctatcaaaag tatacgttcc ttttctttga
      421 tctctggatt taaaacgaga tcatataatt ttagtaccat gttttctatt tcttcacttt
      481 tagacatcac gatttcctcc caaaaatata tttcttccca ctacattcta taaacaaagt
      541 atacgctaca tctagatttt tttaaatcat tactggattg ttaaaacctt tcaatacact
      601 gttatggcaa cgatttttat tttaaaaaca ttctaaatta aatcagtaaa aatttttatt
      661 ctaagatttt tattagaatt acgcctaatt tgtgtctctc agggcaattc taagaacgtt
      721 tcaagagata gcgacactat cgttatcgaa aaaggcgaaa acctatctca ttttctgcta
      781 atgtaagttg gtttagcttt tgttaatatg actttatgaa aatggaggta attaaatatg
      841 atttttccta aagttaatga agcaagcttg aataaaggat ccttttttca tatctatgaa
      901 aacgaagatt ttgaactgta taatatcctt tcacaaaaag aggtcatcga aaaccaaata
      961 atctgccatc caattattta caaatctatt ttcaagtatg cattttttgc ttccaatgat
     1021 tttcaaagaa tggagattac cgactgtata ttcgaaaact gtgatttttc aggctgtata
     1081 ttgacaaaaa gcatgttgca tcgcgtgaaa tttgtcaatt gtaaattaac aggtactaaa
     1141 ttgatggaaa gttatattgg gaacacgtta ttcgagaatt gtaaaatgga ctatgtaaat
     1201 ttatctggtt caaacataaa agaaagtacc tttgagcact ctgtcttatc aagcgcagat
     1261 tttgtagact gttccctcac taaaataatg ttttctacta atgatttaga aaatgctagc
     1321 ttttttgata ctgatttaaa aaatatcgat ttaagtagca actcctttga aatgattgaa
     1381 gtacgctcgg aacatctaaa aaattgtacg cttaatcagt tgcaagcact tggttttgct
     1441 agaaaatttt tacaaat
//
LOCUS       DAZKCH010000196         1447 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000196 DAZKCH010000000
VERSION     DAZKCH010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.204"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(137..427)
                     /locus_tag="ACG84X_002896"
     CDS             complement(137..427)
                     /locus_tag="ACG84X_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128687.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(545..805)
                     /locus_tag="ACG84X_002897"
     CDS             complement(545..805)
                     /locus_tag="ACG84X_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128688.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(942..1355)
                     /locus_tag="ACG84X_002898"
     CDS             complement(942..1355)
                     /locus_tag="ACG84X_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFP9128689.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
BASE COUNT          531 a          238 c          214 g          464 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagcttt
//
LOCUS       DAZKCH010000197         1428 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000197 DAZKCH010000000
VERSION     DAZKCH010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.205"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            43..453
                     /locus_tag="ACG84X_002899"
     CDS             43..453
                     /locus_tag="ACG84X_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFP9128690.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            467..823
                     /locus_tag="ACG84X_002900"
     CDS             467..823
                     /locus_tag="ACG84X_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFP9128691.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          526 a          210 c          267 g          425 t
ORIGIN      
        1 aattactgta gaattggatt ataattaaaa aggagtgaga aaatgataaa agtatatact
       61 tcgcctagct gtacttcctg tagaaaagca agagcatggt tgcaagcgaa tcaacttgaa
      121 tttgaagaga agaatatttt tgccgaaccg ttaacagaaa gtgagatcaa aaagatcttg
      181 gcagcgactg aaggaggagt tcaagatatt atttccactc ggtcgaaaat ttacgaaaag
      241 ctgggcatag attttaacga attaacttta aagcaaatga tcgtcttatt caaagaatat
      301 ccttcattat tgagacgacc tattttgatt gatgaaaaaa gaatactaat cggatttaat
      361 gaagatgaga tccggtcatt tgtccctcgt gaaattcgat gtgttgccag aaatctgatc
      421 tatttacaaa acaataacat cttaaattca tagggaggga gccttcgtgg aagtgaaagt
      481 ctatggatca gcgcactgtg taacaagtct gaaggcgaaa caatggttag aacaccatca
      541 attgccttat caatttgttg acttagaaga acgcgatcta agtacagaag aagcagaaga
      601 attatgcagt tttgaagaag tgcaagcaga acagctattt gcgacttggt ctgaggcttt
      661 tcacaacatt gcgattgacc tttcctgtgt aggaaaaaaa caactgattt ttttatgcac
      721 acaacatacc aatctcctca gacgtccttt gattattatc gatgaagttc tatttattgg
      781 atacaatgag cagttgatgg aacagcttat cttaaataaa tagactttaa ctgttttaat
      841 caagtcactg agcatttcat acagttgtaa cagtcgaaca cttagcatca agcgtgttat
      901 gtgttctttt tttgacttta tttttctact atagagacat gctcaattta tgtggtcaaa
      961 attcaaatct aggtggggat atagagttaa aaatatattg acatgtgtaa atttacatga
     1021 tatattcatt tctgttgttt taagtagcaa agcaataaaa tagtatttta aaaaacatat
     1081 aaaatagttg ttgacatgtt agaaatgaca tgataagata actgagttgt taaaaaagaa
     1141 ccacttgtga agcttgattc tatcgaaaaa aacttcaaaa aagttcttga caaataacaa
     1201 atgataagtt atgataaatg agttgctgta agatttcgaa aaacgaaatc aaaaaaactt
     1261 ttaaaaaaga gttgacaatt acttgtctct ctgatatgat ataaaagttg ctacggcagc
     1321 caaaaacgaa tcggggaaca ctcctgatga agtagacctt tgaaaactga acaaagtaag
     1381 acaaaccaaa tgtgtagggc gtcttgattc aattcaagac aacaaaca
//
LOCUS       DAZKCH010000198         1417 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000198 DAZKCH010000000
VERSION     DAZKCH010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.206"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(150..1337)
                     /locus_tag="ACG84X_002901"
     CDS             complement(150..1337)
                     /locus_tag="ACG84X_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFP9128692.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          412 a          308 c          249 g          448 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttc
//
LOCUS       DAZKCH010000199         1379 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000199 DAZKCH010000000
VERSION     DAZKCH010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1379
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.207"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..658
                     /locus_tag="ACG84X_002902"
     CDS             <1..658
                     /locus_tag="ACG84X_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HFP9128693.1"
                     /translation="SLIVESQEKNYIDFCDITTIIGWFLAISCACFITLFQPFMIIWV
                     GSDNLMSISFVIFMIVHFFLYEIDQLIGLYKDAAGIWYADRFRPLITAMINIVLNIIL
                     VNWFGLYGVLAATIVSVLLVDLPWLLYNVFQNIFKFESAGKYVWKLISLCVIAFVASY
                     LSYFACSYVNIGNFKVISLVINLVISVVISILVILLFNIRNKKFKYILKVLTSVLVKR
                     "
     gene            836..1057
                     /locus_tag="ACG84X_002903"
     CDS             836..1057
                     /locus_tag="ACG84X_002903"
                     /inference="COORDINATES: protein motif:HMM:NF012360.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFP9128694.1"
                     /translation="MGSSERIKIGNNVFIGMKSRILKGVHIGNNVVIGANSLVNKDVS
                     DDCVVAGNLAKVIMSLDEYYKKINNMKNP"
BASE COUNT          469 a          135 c          282 g          493 t
ORIGIN      
        1 cagtcttatt gtagaaagtc aagaaaaaaa ttatatagat ttttgtgata ttacaacaat
       61 tataggttgg tttctggcaa ttagttgtgc atgctttatt acattatttc agccgttcat
      121 gattatctgg gtgggaagtg ataatcttat gagtatttca tttgttatat ttatgatagt
      181 tcattttttc ttatatgaaa ttgatcagtt aattgggtta tacaaagatg ctgctggaat
      241 atggtacgca gacaggttta gaccattaat tacagcaatg ataaacattg tattaaatat
      301 catcctcgtt aattggttcg gattatatgg agttttggcg gcaaccattg tttcagtatt
      361 gttggttgat ttaccctggt tattatataa tgttttccaa aatatattta aatttgaatc
      421 ggcaggtaaa tatgtttgga agctcataag tttgtgtgta atagcttttg ttgcttctta
      481 tttaagttat tttgcttgtt cgtatgttaa tatcggaaat ttcaaagtga taagtttagt
      541 gataaattta gttatatcgg ttgtcatatc gattttagtt attcttctgt ttaatatccg
      601 taataagaag tttaagtata ttttgaaagt tcttacgtcg gtattggtaa aaagatgaga
      661 agagacatca gaatgatata taaagtaact acaattttta ggctgccgaa taggcgaacg
      721 atgtatagtt tttgttccaa cgaagactct tgttgaaatt ggagatgata tgaaggagtt
      781 acaattttga ctcatgttta tgattgatcg gttttaaaag tagtatggag aagctttggg
      841 atcatcggag aggatcaaaa taggtaataa tgtttttata ggaatgaagt ctagaatact
      901 aaagggtgta catataggaa ataatgtagt tataggtgca aatagtttag taaacaagga
      961 cgtatcagac gattgtgttg ttgcaggaaa tctagcaaaa gtaattatgt ccctagatga
     1021 atattataaa aagataaaca atatgaagaa tccgtaaaac ttgtgaaact ataccgagaa
     1081 taatatggga aaaatattga tgaaaaagca ttatatgagt ttttagggct gtttacagat
     1141 ggagatgaca atttgtcgaa gagttgggag caatgcaaaa tttagtaggg gattataaac
     1201 agactgacaa ggtatttaaa gaacatgcac aagtatttca taatattgaa gaatttttga
     1261 atactgtgag ataggagttg ctacattgag aaaagtatgt atttttccaa tgtaaaagat
     1321 tacgagtttg aaaacgacac cataatatta ttttttaaga agatattata gagcttagg
//
LOCUS       DAZKCH010000200         1364 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000200 DAZKCH010000000
VERSION     DAZKCH010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.209"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>1364
                     /locus_tag="ACG84X_002904"
     CDS             82..>1364
                     /locus_tag="ACG84X_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFP9128695.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAZKCH010000201         1364 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000201 DAZKCH010000000
VERSION     DAZKCH010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.210"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="ACG84X_002905"
     CDS             complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="ACG84X_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="HFP9128696.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          393 a          242 c          216 g          513 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcagatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgcc
//
LOCUS       DAZKCH010000202         1352 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000202 DAZKCH010000000
VERSION     DAZKCH010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.211"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..459
                     /locus_tag="ACG84X_002906"
     CDS             <1..459
                     /locus_tag="ACG84X_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128697.1"
                     /translation="AKYLKTHVEAIDGKEALVQTDGDQAIAGHKNFSGSVTINNKRVL
                     TTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGNDSVILTVPEGYR
                     TPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVITYSI"
     gene            473..904
                     /locus_tag="ACG84X_002907"
     CDS             473..904
                     /locus_tag="ACG84X_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128698.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            906..1043
                     /locus_tag="ACG84X_002908"
     CDS             906..1043
                     /locus_tag="ACG84X_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFP9128699.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITEEEADKIISKEESA
                     S"
     gene            1081..>1352
                     /locus_tag="ACG84X_002909"
     CDS             1081..>1352
                     /locus_tag="ACG84X_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128700.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKT"
BASE COUNT          506 a          196 c          278 g          372 t
ORIGIN      
        1 gctaaatact taaaaacgca tgtagaagct attgatggta aagaagcatt ggtgcagaca
       61 gatggagacc aagccattgc aggacataag aatttttcag gttctgtaac aatcaataat
      121 aaacgtgttt tgacgactga tgataacaga tatgaagtgg taaatctggt tgtcactaac
      181 ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa cagtttctat atattttgtg
      241 gctttaaacg gaaaaagtag tggcgggaat gattcggtta ttttaactgt tccagaaggc
      301 tatcggacac caattagttt tgaacaactg gttgggtcaa tagaccgttc tactttgaac
      361 agtgctcaac tatctattgg cgcagacgga gccattaaat ggagaagaaa ttcaagttat
      421 ggatcagctt attcatttgt tatcacttat tcaatttaag ggaggaaatc taatgaaagt
      481 agtttacaaa tcaatcaagc cttacggatt cgagcaaatc attttgaaca atcaagaaaa
      541 tatccctgaa aactgtacag agattaaacc accagttcct aactggagac caagatttga
      601 ttttgataaa aaacagtggg ttgagttagc tactgaagaa gagaaaaaag ggaatgctgt
      661 tgatagcgta gatgaattgg ctaatattaa ggcattatac gaaacgctga aggcagaaaa
      721 tgatgaattg aaacagctaa attctaaagc aatgctaaac aatgtagcaa tcaagcaaga
      781 aaatgtctta ttgaaagaaa agtcagaaag tttagcgcag ttgaattcaa aaacgatgct
      841 tgcttctgta caaaatacca aggaaatcga agaaatcaaa aaacaattac aaggtgggaa
      901 gtaacatgta ttcatatgaa gatatcaaac taatgtatga ctggggctgt ttcactaacg
      961 aacaagtaat ggttttcgtt ccgttgtgca ttactgaaga agaagcagat aaaatcatta
     1021 gcaaagaaga gagcgcatct taattgatgt gctttttatt ttgattcaag gagttgtcac
     1081 atgattaatt taggggaatg gggagcgata gcaggatcaa taaccgctat cgtttctttg
     1141 attttattag taataaaacc aattactgca tctttctcga agattactga gactctttca
     1201 aaagtaagtc acaatttaga tttgctgact aaagatttag aatcgagcaa atcagatcga
     1261 ttgatgattc atgaagaact aaagaaacac gatgaaagat tagatacaca tacagaaaaa
     1321 ttggtggaac acacgcaaca aattaaaact tt
//
LOCUS       DAZKCH010000203         1341 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000203 DAZKCH010000000
VERSION     DAZKCH010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.212"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..951
                     /locus_tag="ACG84X_002910"
     CDS             <1..951
                     /locus_tag="ACG84X_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HFP9128701.1"
                     /translation="IKNKLSLLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFD
                     SEVKGLLNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSY
                     LVKITEEKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANA
                     DVEKELYANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGM
                     TRRLEPMDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEF
                     FKVSLDEIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1023..>1341
                     /locus_tag="ACG84X_002911"
     CDS             1023..>1341
                     /locus_tag="ACG84X_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128702.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVK"
BASE COUNT          590 a          154 c          215 g          382 t
ORIGIN      
        1 ataaaaaata agctttcttt gttaaaatta aaagaaaagg aatatattat tgacgatgct
       61 gtttctgtcc ctcttatttt aaataaacga gagaaaaata atttaaagaa aaaaatgctc
      121 attccatttg attcagaagt gaaaggatta ctcaataaac taactatttc taatatagac
      181 tcgactaggg aaaaaatcat aaaaatattt gataaaatta ataatttatt caagaatgac
      241 aatgctgaat taaggaaggg tcttttagag tttaaacttc aagaactaga acttcattac
      301 tcttatttag tgaaaattac cgaagaaaaa gaacaacaaa aagcaataaa agaacagatg
      361 atagaagagg aaaaagttcg tagagaaatt gatcgtgaaa agaaacgtat tgataaagaa
      421 caacgtcaat tcaattctga aatttccaaa ttaatcgcat atatgcaaaa agctaatgca
      481 gatgtggaaa aagaattata tgcaaataaa attcaagaac tggaagaaaa attaaaagaa
      541 ttagaagtta tacgtgaaaa tgtattacaa agagaattaa atactagagc cggttatgtg
      601 tatgtaatta gtaatattgg gtcttttggt gaagacatat ataaaattgg tatgactaga
      661 agattagaac ctatggatag aataaaagaa ttgagtagtg catcggttcc atttgaattt
      721 gacgttcatg cgatgatttt ttcagaggac gctccgtctt tggaaactaa attgcataat
      781 cattttagaa aacaagaagt taataaaatt aatcaaagaa aagaattttt caaagtttca
      841 ctagacgaaa tagagaaagt tgttttagaa aattataatg gaacagtaac atttacaaaa
      901 ttagctaaag ctgaacaata tagacgatct ttagaattgt caaaagatta aatatataaa
      961 aagccttcgg gctttttctt ttaacaatta ataggaacgt atattcgaaa ggaatagaaa
     1021 taatgtggtt agaaaaaata aatgacaaaa aatttaagta caccgaacgt tatacggatc
     1081 ccttaactga aaaaaagaga aaagtgtccg ttactttatc tagcaattca cgccaagctt
     1141 ggaatcaagc taacttactt ttgaatgaaa aaatcgcaga aaaaataaaa cgaaatgaag
     1201 aattaccact aacttttgga gaattaaaaa ctaaatggga tgaaaaatac aagccaactg
     1261 taaaagaaag ttcctatcga acaactcagg tttatctatc attaatttca aaatatataa
     1321 aagatgatgt acttgtaaaa a
//
LOCUS       DAZKCH010000204         1324 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000204 DAZKCH010000000
VERSION     DAZKCH010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.213"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            278..820
                     /locus_tag="ACG84X_002912"
     CDS             278..820
                     /locus_tag="ACG84X_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128703.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            976..>1324
                     /locus_tag="ACG84X_002913"
     CDS             976..>1324
                     /locus_tag="ACG84X_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFP9128704.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          533 a          157 c          248 g          386 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcaaat tgatgaagca gatcccaaag ggctgcttca tcaatttttt
      121 cgtaagtgtc cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt
      181 gtaagaacaa ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa
      241 attatatttc atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa
      301 atgctattgt gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc
      361 atgcctatta cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga
      421 aaacaataaa ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa
      481 tgcaaatggc aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga
      541 atatgtttat gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat
      601 agctgataaa aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta
      661 tgctattttg acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat
      721 gggcgatgga tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt
      781 tgaaaaaaat acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa
      841 ataggagttt caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa
      901 agtaatcttc tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt
      961 cctaaaaatg gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac
     1021 aaagaatcgg ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt
     1081 acaagtaaag attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt
     1141 acagcttgtg taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag
     1201 ggtgtaaata tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa
     1261 gcaattgaaa agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg
     1321 ccag
//
LOCUS       DAZKCH010000205         1308 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000205 DAZKCH010000000
VERSION     DAZKCH010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.214"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..430)
                     /locus_tag="ACG84X_002914"
     CDS             complement(<1..430)
                     /locus_tag="ACG84X_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9128705.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
     gene            complement(500..1078)
                     /locus_tag="ACG84X_002915"
                     /pseudo
     CDS             complement(500..1078)
                     /locus_tag="ACG84X_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            1156..>1308
                     /locus_tag="ACG84X_002916"
     CDS             1156..>1308
                     /locus_tag="ACG84X_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9128706.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTS"
BASE COUNT          393 a          254 c          216 g          445 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tctaactttt ggggtgcaca
      481 tcaaagaggg gggaattttt tatcgttgtg gaatatttaa ataccaacgc ttgtcatgaa
      541 aatcttgtgc tccaccctta gtatttcctt ctggatcgtt tgtcgcacgc atcatgacgt
      601 atactttctt attagggaaa tcacgcatat tgaaagatac atgatagcca acatttccta
      661 aagtattata agcttgattt acgtctggtc tataaatccc atcagctctt actctagcta
      721 gttcttttcc agtattgtag tccataatga aaatatactc gtatttataa ttagcaatgt
      781 gccatccagc tacatgcaag tttgcgtttt cgatttctcc gaactgatca acgtgggcgt
      841 aatttgttcc atctgtcagc gtagaatttg cagcacctgc tcgagttgga tcaattactg
      901 gtttatcctc cgaagtagtt ggattatcat ccgaagtagt tggattatca tccgtaaaac
      961 catgagccaa atcataggct agtttttctt tacttacacc catttcagaa agataaccgc
     1021 aaggatctgt atgatcgccc caaatatttt gtgttaccca taaatgcgat ttgattcctg
     1081 tggataggct acaattaact agacagaaaa attaaggtgt gtagactaga agaaaacata
     1141 ccaggaggaa tttttatgtc taagagaaca cgaagaactt tttcacaaga attcaagcaa
     1201 caaatcgtca atctttactt agctggaaag ccacgtgtag aaatcattcg agaatatgaa
     1261 ctaacggctt cagcatttga caaatgggta aagcaatcta aaacgagt
//
LOCUS       DAZKCH010000206         1294 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000206 DAZKCH010000000
VERSION     DAZKCH010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.215"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1244
                     /locus_tag="ACG84X_002917"
     CDS             <1..1244
                     /locus_tag="ACG84X_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFP9128707.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DAZKCH010000207         1232 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000207 DAZKCH010000000
VERSION     DAZKCH010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.216"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..196
                     /locus_tag="ACG84X_002918"
     CDS             <1..196
                     /locus_tag="ACG84X_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFP9128708.1"
                     /translation="SFKPEFLKKSNYIFDGQCGIIKMRDYLILDIDSEEDFKWLEFLF
                     PKFLEDSSELQDIYNYLYRR"
     gene            201..1148
                     /locus_tag="ACG84X_002919"
     CDS             201..1148
                     /locus_tag="ACG84X_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFP9128709.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          402 a          176 c          257 g          397 t
ORIGIN      
        1 ttcttttaaa cctgaatttc taaaaaaaag taattatatt tttgatgggc aatgtgggat
       61 aataaaaatg agagattatc taattttaga tattgatagt gaagaagatt ttaaatggtt
      121 agaatttttg tttcctaaat ttttagaaga ttcttcggag cttcaagata tctataatta
      181 tttatatcgg aggtaaaagg atgagctgtt atcttatcac cggtggggct ggcttcattg
      241 gttctacctt agccaatcat ttaggagaag aacatgtggt aatcgtcgtc gatgacttat
      301 caatgggaaa agtagaaaat cttgatatga cgaaaaatat cacttttatt gagggagatg
      361 tcgctgagaa atccttgatg gaagagatca tgaaagctaa taaatttgat tatatctttc
      421 atttagcagc agttgctagt gtggcagatt cagttgcccg accagtagaa acacatcgtg
      481 tgaattttga aagtgtatta atgattttag aattgatccg caagtatcaa cctgatttaa
      541 aacggatcgt gtttagttct tcagcggctg tttatgggga tgaaccgact ttaccaaaaa
      601 aagaagagtc cgtgattcgc ccattgacgc cttatgcggt tgataaattc gctgcagaac
      661 aatatgtgct agattattgt catttatatg atgtacccgg tagcgcagtt cgttttttca
      721 atgtctatgg tccaaatcaa aatccgaatt ctccatacag tggtgtgatt tctattctcg
      781 tagatcgcta taagaaacaa atcgtaggag aagcaacttc atttacatta tttggtgatg
      841 gaagccagtc tagagacttt gtttatatag atgatgtaat ccaagcatta cttttagttg
      901 cgaatgagga agctgcactg gggaaacaat tcaatgttgg aacgggtaaa gcaaccacac
      961 ttttggaatt gattcatgca atcaatgaaa ttctcggtgt agaattgaca cttgaataca
     1021 aagaagagcg ttcgggtgat atccatgact ctctagcaga tattactaag atccagtcaa
     1081 ttggctatca accgaaatat ggtattttaa gtggaatgac taattatttg aaaactgaaa
     1141 tcaattaaaa catactaaga taagattaga gggtaaattc aggctctttg tcaataagga
     1201 ctgatgagtt ttgtaaaatc aaatctggga ta
//
LOCUS       DAZKCH010000208         1199 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000208 DAZKCH010000000
VERSION     DAZKCH010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.217"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(102..473)
                     /locus_tag="ACG84X_002920"
     CDS             complement(102..473)
                     /locus_tag="ACG84X_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128710.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(475..876)
                     /locus_tag="ACG84X_002921"
     CDS             complement(475..876)
                     /locus_tag="ACG84X_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128711.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            complement(890..>1199)
                     /locus_tag="ACG84X_002922"
     CDS             complement(890..>1199)
                     /locus_tag="ACG84X_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128712.1"
                     /translation="NAPLIPTALSFSVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFST
                     GEVSVSLPPQVNDINFNINARNVLVEEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN
                     "
BASE COUNT          381 a          217 c          156 g          445 t
ORIGIN      
        1 agcgatcatc ggcgttatga ctatataaag tatactttcg ttgatccaga aagatacaaa
       61 gattaaataa aaaaataaca aacaaactcg cttgaaattc attaggtgag tttgtttatt
      121 attttttctg cttctcgatt catcagcgcc atatctgttt tcgtaatggt ttcattagga
      181 atatagtcag cacattttct tttctctaac attctatacc cactattatg tattcctaag
      241 gtattcaatt ccttaactgt tgaaaacaaa ttccaaacgg tttggtggct tccttttccg
      301 ctacttccat tataaataat atcataattt tctttcaaat actcatcaga ttttttaaaa
      361 gcactgtagt atgctcttga aacagcagtt cttctataag attctttaga attatattta
      421 tcatctgatt caatttgttt ggaaatagat aaatattcat taaagtcaaa cattttattc
      481 ccccaaagtt gctactacag atttccccat atatttatag tcagataata cattatcgag
      541 agtatccaaa acatcgtaat ctgaggaaaa caattcagat gttgttttga taacaaagaa
      601 atacaagttt aaatcttcat catattttat attgatttca gcttttcttt ttaaaaccgt
      661 atttatcaca tcaaaaattt tgccatcatt acttgaaatt gtgttaatct cattttttgt
      721 agtaattaca agttgattat catttttagt tttcggagta gaacttgcat ccacaacaac
      781 tggagatgct agaattaccg atgcgcaagc aaaaatcgca gcaaaattta ttaagctacc
      841 actccgatgt gtatttgatg gtactatatc aagcatccgt atcgtctcct taattttttt
      901 ccactggttt gttgaccttg atatcaaaga tttgccttcc aatctcagtt ccattaaatt
      961 taacaacagc ataatgctct cctgcttctt caaccaagac atttctggcg tttatattaa
     1021 agtttatatc gttaacttga ggaggcaagc ttaccgatac ttcacccgta gaaaaaattt
     1081 gtttttcatt cttgtttaaa acttcaattt ctactatttt tatcttttct gtatcctcta
     1141 tctcagacac cacagctgtt acagaaaatg ataaagcagt aggaattaaa ggcgcatta
//
LOCUS       DAZKCH010000209         1170 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000209 DAZKCH010000000
VERSION     DAZKCH010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.218"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..983
                     /locus_tag="ACG84X_002923"
     CDS             <1..983
                     /locus_tag="ACG84X_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFP9128713.1"
                     /translation="TALFLLPINGFAYTINNEFNLGANEGSSQVANNQYILLHETANE
                     TATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQ
                     HTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDP
                     YGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHID
                     QFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYNTSGN
                     VGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          392 a          217 c          232 g          329 t
ORIGIN      
        1 taacggctct ttttttattg ccaattaacg gatttgccta tactatcaac aatgaattta
       61 atttgggcgc aaatgaaggt agctcacaag tagcaaataa tcagtatatt ttactgcatg
      121 aaacggctaa tgaaacagca acaggacgca atgaagcgca gtatatgcaa cgttcatgga
      181 ctagcgctta tactgcttat attgtgggag acggcggaat tgtttatcaa gtcggtcaac
      241 ctggttatgt acagtacggt gctggttcgt atgctaatgc caacagtcct gtgcagattg
      301 agttacaaca cacacatgat aaagcaacgt ttgagaaaaa ctacaaggca tacgttgaat
      361 tggctagaga ttcagcaatg aaatatggta ttccattaac gttggacact ccttataacc
      421 aaccgggaat caaatcgcat ttatgggtaa cacaaaacat ctggggcgat catacagatc
      481 cttacggtta tctttctgaa atgggcgtaa gtaaagaaaa attagcatat gatttagctc
      541 atggatttac cgatgaaaat ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac
      601 gagctggtgc agctaatcct acactgacag atggaacgaa ttacgcccac attgatcagt
      661 ttggagaaat cgaaaatgca aatttgcatg tagctggatg gcacattgct aactataaat
      721 acgagtatat cttcattatg gattacaata ctgggaaaga attagctcga gtaagagctg
      781 atggaattta tagatcagat gtaaatcaag cttataatac ttctggaaat gttggctatc
      841 atgtatcttt taacatgcgt aacttcccta ataagaaagt ctatgtcatg atgcgggcaa
      901 cgaatgatcc agagggaaac actaaaggcg gtgcgcaaga tttccatgac aaacgttggt
      961 atttaaatat tcctaaacga taaaaatagc tcctcgttga ggagcattac ataactatat
     1021 tgacaactat aaaaatcatt cgataaaata gtgatgttat cgcatatctt cactatcacc
     1081 cataatagtc acactccaag ctatgcgata acaggtttgt tgccacacat tctactggtt
     1141 gattgtttat ggctttatgt ggcaacaacc
//
LOCUS       DAZKCH010000210         1145 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000210 DAZKCH010000000
VERSION     DAZKCH010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.219"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..494
                     /locus_tag="ACG84X_002924"
     CDS             <1..494
                     /locus_tag="ACG84X_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFP9128714.1"
                     /translation="TDFINENKGDFTDWMNERKEEFDRWREEQENSFQDWREGQESDY
                     LSWFESIKDILKSIDPGGVMLAELMDARVDLQGVRHESISERFLSDLNYLYQKMKAAL
                     FTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPIEEGALIIATVDDPKQNVFTLEKV
                     GVI"
     gene            494..1111
                     /locus_tag="ACG84X_002925"
     CDS             494..1111
                     /locus_tag="ACG84X_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128715.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          422 a          147 c          249 g          327 t
ORIGIN      
        1 tgacagattt tattaatgaa aataaaggcg attttacgga ctggatgaat gaaaggaaag
       61 aagaatttga tcgctggaga gaagaacagg agaatagttt ccaagattgg agagaaggac
      121 aagaatcaga ttatttgtca tggtttgaat caatcaagga tattttgaag tctatcgatc
      181 caggtggagt aatgttagcc gaattaatgg atgcacgtgt agatcttcaa ggtgtacgcc
      241 atgaatcgat ttctgaacgt ttcctatccg atctaaatta tttgtatcaa aaaatgaaag
      301 cagcactttt cacgattgaa tacggtgaaa ttgaagtgac tgatattctt caagacgatc
      361 tcttttcaga taatcacgaa gtcgaaaaaa ttgaaacagt agaatttcca attgaagaag
      421 gagctttgat tattgcaact gttgatgatc caaaacagaa tgttttcact cttgagaaag
      481 ttggggtgat ttgatggtta aagtaaagag aatgatggag actgatgaat ctggtgttaa
      541 acgtcaattt atgccaatta cacatgtttc tgcagtttta ggcttagaaa aaatgatatc
      601 aggacaatca aaagttcttt cggttaatgg taaatatggt gcagtcattt taacgaaagc
      661 tgatttagga ttagagaatg caattactga actaccttat gcaagcgaga caagcgatgg
      721 tattcttact gctgaaatgt ttcaaaagat cgtaaatgga gaaggtggaa catatatttt
      781 gccgattgct actcctgaac aattaggagg tataaaagtt ggggaactct tagaagttac
      841 tgaagaaggt gttttatctg caactaagca aacagacttc aatttctctg aagaattaaa
      901 gggaaaatta gaatctctaa aaatattaaa agcaggtgca aatatatcaa ttgcagaaga
      961 tggaacaatt agttctacag gtggtagtgg gactggtggt gttaatcagt catatgtaga
     1021 tcaaaaattc caagaagctg taaatcaagc agaaaattac acaaacgaaa gaattccaaa
     1081 ttttactttt gaaaaaatcg gggaggtata gaaaatgaca gatatcgtaa aaataaaaca
     1141 aagcg
//
LOCUS       DAZKCH010000211         1141 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000211 DAZKCH010000000
VERSION     DAZKCH010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.220"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            460..606
                     /locus_tag="ACG84X_002926"
                     /pseudo
     CDS             460..606
                     /locus_tag="ACG84X_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            complement(694..987)
                     /locus_tag="ACG84X_002927"
     CDS             complement(694..987)
                     /locus_tag="ACG84X_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFP9128716.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT          352 a          187 c          165 g          437 t
ORIGIN      
        1 ttatttttaa ataaaaaata ctcttttttt acgattattg aaaaaaaaag ataaaacttg
       61 attaattgaa gtattgctta aatttggaag ctatgaggga agaataaaag agttaggacg
      121 ggattatcta ctatttttct ttgttttaaa tatttgttat ctttgaacat aaaagagaaa
      181 tgtgtcgact gcagtgttgt gtccctcatc acgaataaac ggtgttcaac tagctgatct
      241 tgtattcact taaaaaatgg taaagtacga gttgctattc cccattttca attttctaac
      301 gctcaggaca aaatactgtt ttcacaacct cattggaata aaagcatata tattgtttca
      361 agaacgaaat cttgttatct ttttaaaggg catctgtcca aaatctaatt ttaggaggta
      421 cgttttggta tttattcgta caaataaaag agaattatct ttattcatgt aacgcatcca
      481 attgattttt tcatgtacgc tcctggaacg attttactga cgattgctta tttaactgcg
      541 aatcgctcat tagcttttat catagctatc catattttga ataacgttct tggctttgta
      601 ttatagatac agatgacaaa aaaagttcaa gtatgcggtg tagaaccaat atcgcatact
      661 tgaacttttt tcaatgagta taaattaaaa cttctaattt tcaattccca tcatctgata
      721 tgcccgaccg tctgaacttc ttttgaaaaa gccaaatgtg attagataac gtctttgttc
      781 gacataatcg ccactagaaa atacgttcag cagtatcgaa ttaacctctg tttctgtata
      841 agtcactcca tggtcaaagc gtttcaagac ttctttcaat aggatgtatt tcttttttgt
      901 tgaacttggt acttgtttta cttttccatc attcatgaat gtgtctaaaa ctttcatctt
      961 ttcttgctcc gtataagtat aaaccatctt ctttctcctt ttgattctaa gaatactcca
     1021 tttatgttag aatattctgg attttttatt aaagcggtta ctcttaagaa agatattatc
     1081 atagtgctct tttttttact actacttata ggtagattta ttctaatcca ttattctccc
     1141 c
//
LOCUS       DAZKCH010000212         1137 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000212 DAZKCH010000000
VERSION     DAZKCH010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.221"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..355
                     /locus_tag="ACG84X_002928"
     CDS             <1..355
                     /locus_tag="ACG84X_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128717.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
     gene            615..910
                     /locus_tag="ACG84X_002929"
                     /pseudo
     CDS             615..910
                     /locus_tag="ACG84X_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            985..>1137
                     /locus_tag="ACG84X_002930"
     CDS             985..>1137
                     /locus_tag="ACG84X_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFP9128718.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
BASE COUNT          431 a          135 c          237 g          334 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcat
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aacaagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaactatt
      601 aggaggagat gtaggtgaaa aagtttaaaa agaaaatata tttaggattg gttgttgggg
      661 tgagtatgtt tgggttcatg gctcatacta aacaagtaac tgcagatact aaccaaaaag
      721 aaaggattat gagccaatta gatgactctc aaataagtat gtacccaatg agctaattgt
      781 cagtttaaag gctacacaaa gaatttcaac agagaaaaat aaaccgcaaa atttattggg
      841 tgtaaaagtt atggtggaaa aagatttgac tcttaggaca aatgaaagcg attgtaataa
      901 gcgagatcaa gggttctgtt gcaaagtttt ccaaaaaatc tattttagtg taaaattgag
      961 aaaaaagaca gagaggacag agtaatgaat cattttaaag gcaaacaatt caaaaaagac
     1021 gtcattattg tcgctgttgg ttactacctg cgttacaatc taagctatcg tgaagttcag
     1081 gaattgttat atgatcgtgg aataaatgtt tgtcatacta cgatttatcg ttgggta
//
LOCUS       DAZKCH010000213         1137 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000213 DAZKCH010000000
VERSION     DAZKCH010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.222"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            427..813
                     /locus_tag="ACG84X_002931"
     CDS             427..813
                     /locus_tag="ACG84X_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFP9128719.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            907..1098
                     /locus_tag="ACG84X_002932"
     CDS             907..1098
                     /locus_tag="ACG84X_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128720.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
BASE COUNT          425 a          167 c          178 g          367 t
ORIGIN      
        1 ttcgtttcta aatattccaa tttgggaatc caataaaaat tttcgttcaa atacgtgtct
       61 attcgaactc ttttctagtt gttaattatg aagggggaag aaataaaaaa tacaatctat
      121 acacgaataa gaatattatc caaaaggagg ttttagaaaa gatttattat acgtaaaaag
      181 ctcaagacat tttcttagcc ataaggacat gtttgatatt taagaagata tatgaatttt
      241 cttttctaag tataaagata actatccatt atcaactaaa aaaacatttt tgaaaataaa
      301 catcagcagt cctatcaatg catgtgagct tatagaagtt attcgcagcg cagcataatt
      361 gcattagctt cttttcgtgt tttttgcctc ttttcccttt aaatcttaat ggaggaggtg
      421 tgcaatatgt cagataacga cgaacgcgta aatgcccagt tgattcgatt ctttgaaaag
      481 gtcattttga acaccgctaa tacttattat aaaaaacaag aagaaattca aaaacatgaa
      541 caacttgatc aactcccacc atatttgttt actaaagata ctataaaatt taaacaaccg
      601 attaatgttt taaatgtgac tctccttgtt gaagatataa aattagcaaa aatccttcct
      661 ttgttgaaag aacctgaaca aatttttctt atcgaaaaat ttatctttga taaaactgat
      721 aaagaaattg gaaaggttct ggggattaca agacagggtg cgacaaattt aaaacatcga
      781 ctttacaaaa aaattcaaaa aatgctggtt taatatctgc ataataacta attttgtatg
      841 cttctttgct cgttctcctc cttcccaaag aaatagatta taagtccatg ggaagaaggt
      901 agatttatga attctttaaa agaagatttc attttagcaa aggctggaaa tgaagaagct
      961 gttgaggcaa ttctcaaaag atttagctct ttgattcata agcaatcctg gagaactgga
     1021 aaatatgatc aagattgtta tcaagaatgt atgcttgcaa tatatctagc tatctcgaaa
     1081 ttcgaaatta aagaataact caactaaggg agtctgtgac ataagtaaaa agatagt
//
LOCUS       DAZKCH010000214         1080 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000214 DAZKCH010000000
VERSION     DAZKCH010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1080
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.223"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(153..>1080)
                     /locus_tag="ACG84X_002933"
     CDS             complement(153..>1080)
                     /locus_tag="ACG84X_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFP9128721.1"
                     /translation="FFKLKMNNLNVAMADRERLYNSLQNLTLYSLGDIRDILILVHYF
                     FTGKIEDLFHEPLIEYTENLSKTIEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGD
                     IRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDA
                     LIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITV
                     KEIANYFSVSETKLRESFKNEMHITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFS
                     DSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
BASE COUNT          375 a          186 c          126 g          393 t
ORIGIN      
        1 ttaacacact attattacca ttacttagac gctcagattc tacgaaacaa ctcaaatcag
       61 aaatttccca aaaaaatttt ttgttaaaat ccaatttcct caactcctcc aaactacgta
      121 aatgatatag tctcataata aaataaaacc tctcagctaa tgttgttgaa attgtccact
      181 aaacctaatt gatattgctt aggagataca cctgcgtact ttttgaatac tctcgaaaag
      241 tgtgaagaat ctgaaaatcc taaacctaaa gaaacttcac tgatagtatg gtttgatttc
      301 aacattattt tagccgtaga aatttttcgc ttagagatat aattataaat cgtaatatgc
      361 atttcattct taaagctttc tcttaattta gtttcactta cagaaaaata attagctatt
      421 tcctttacag taattctttt atagatattt aagccgatga attgaacgac agaagaaatt
      481 aagggagaaa gatgctctat cttagttttt ccgatttcct tagtataata aacaatccca
      541 gaatccctca cttttaagac ctcaggtaac gatacagcta attcgttttc ttgtatcaaa
      601 gcatctctac tttgatacgc ttctattata tccattccta atgttataga cgtttgtgct
      661 aacttttcaa aaacaatgat agaataattt ttttcagacc gaatcgtatc tccactaaca
      721 cttggaatta ttccattact cagattaaaa accatgtttt ctaaatttcg aatatctcca
      781 tttttaacat attccagtat tttattttca taaagaaaca gatatatttc tggatcgtaa
      841 ttttgtgata acagattatc tattttgatt tgctcgatag ttttacttag attttctgta
      901 tattcaatta acggttcatg gaatagatct tctatttttc cagtaaaaaa ataatgaact
      961 aaaatcagaa tatctcgaat gtctcctaaa gaatacaaag tcaaattttg caatgaatta
     1021 tagagtcgtt ctctatcagc cattgcaaca ttcaaattgt tcatttttag tttaaaaaaa
//
LOCUS       DAZKCH010000215         1073 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.224, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000215 DAZKCH010000000
VERSION     DAZKCH010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.224"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1073
                     /locus_tag="ACG84X_002934"
     rRNA            <1..>1073
                     /locus_tag="ACG84X_002934"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          329 a          214 c          308 g          222 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     1021 ccggggctaa acatattacc gaagctgtgg agtacacctt taggtgtatt ggt
//
LOCUS       DAZKCH010000216         1069 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000216 DAZKCH010000000
VERSION     DAZKCH010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.226"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..969
                     /locus_tag="ACG84X_002935"
     CDS             <1..969
                     /locus_tag="ACG84X_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFP9128722.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DAZKCH010000217         1064 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.227, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000217 DAZKCH010000000
VERSION     DAZKCH010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.227"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(39..>1064)
                     /locus_tag="ACG84X_002936"
     CDS             complement(39..>1064)
                     /locus_tag="ACG84X_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFP9128723.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          346 a          177 c          160 g          381 t
ORIGIN      
        1 ttttagaaaa agcagtcgga ctttctaaaa gaagttcact attcgatcct gtcgatgatt
       61 tcttcaggaa aatcgtctat ttgcttgtca attttgctgt ctttgtattt ctcttcttgg
      121 atagtcaaca aaatctttgt aagattcccc cagtctactg ctcttggcgg atcgagccaa
      181 accactactt gagatgcact ttcttcatat agattattcc tattcgtgat tataacatcc
      241 gggaactcag gctttcctgc ctctatcact tccgtgttca gattaatgta caagcttaaa
      301 tttttcttga taaattgatt ataggcagca ccataagaaa aatcgatgat gatctttact
      361 ggttcagaaa tcagttgaat gggtatgtga ttgatcaata ataataaata actgaaaaaa
      421 agaaaaaatt tatcttgaag caactctttg cgttttgacg ttagatcatt tatatactct
      481 atcaaatagc aataaaatgc tggatagttt tctctaaaaa aagaaacatc aagtggaaat
      541 tcatcagctt tattaatagt gtaatgcaaa agtttaaaat gtattttggt taactctctt
      601 cggatcaatt ggctcgtctc ttctcgcaac agattaaact gattttcaaa actttcaatg
      661 aatcgttcat tcaaccattc gattgtttca tcttcatttt ttctcaagta tttttgatcc
      721 aatttatcat gaagataaag ccaagagagt gtcttattga taaaaataac ggatttttct
      781 cctaatactc cttttaagtg gtaaaatcct atatccgaaa aaaatagcga ctgattgcta
      841 gcaatatcta aagaatcagc ttgttcagcc aacaggttga ttgctaaaaa gtggaataat
      901 ttcttttttt cataagcaga cagaggataa tactgtttta aatcttttaa cattttttct
      961 gtttttataa ttataggtag cgtatacaat tccacaaaac ttatctctgt tgagttaaaa
     1021 agattatata aaaaaagccg aatgttttta ggattccctg tcaa
//
LOCUS       DAZKCH010000218         1056 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.228, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000218 DAZKCH010000000
VERSION     DAZKCH010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.228"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(111..284)
                     /locus_tag="ACG84X_002937"
                     /pseudo
     CDS             complement(111..284)
                     /locus_tag="ACG84X_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(838..924)
                     /locus_tag="ACG84X_002938"
                     /pseudo
     CDS             complement(838..924)
                     /locus_tag="ACG84X_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          370 a          180 c          154 g          352 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctaggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagtta
//
LOCUS       DAZKCH010000219         1037 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.230, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000219 DAZKCH010000000
VERSION     DAZKCH010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.230"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(20..91)
                     /locus_tag="ACG84X_002939"
     tRNA            complement(20..91)
                     /locus_tag="ACG84X_002939"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="ACG84X_002940"
     tRNA            complement(113..200)
                     /locus_tag="ACG84X_002940"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="ACG84X_002941"
     tRNA            complement(225..298)
                     /locus_tag="ACG84X_002941"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="ACG84X_002942"
     tRNA            complement(312..382)
                     /locus_tag="ACG84X_002942"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="ACG84X_002943"
     tRNA            complement(384..459)
                     /locus_tag="ACG84X_002943"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
     gene            complement(478..551)
                     /locus_tag="ACG84X_002944"
     tRNA            complement(478..551)
                     /locus_tag="ACG84X_002944"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(515..517),aa:Met,seq:cat)
     gene            complement(564..653)
                     /locus_tag="ACG84X_002945"
     tRNA            complement(564..653)
                     /locus_tag="ACG84X_002945"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(615..617),aa:Ser,seq:tga)
     gene            complement(677..750)
                     /locus_tag="ACG84X_002946"
     tRNA            complement(677..750)
                     /locus_tag="ACG84X_002946"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(714..716),aa:Ile,seq:cat)
     gene            complement(764..837)
                     /locus_tag="ACG84X_002947"
     tRNA            complement(764..837)
                     /locus_tag="ACG84X_002947"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(801..803),aa:Met,seq:cat)
     gene            complement(865..937)
                     /locus_tag="ACG84X_002948"
     tRNA            complement(865..937)
                     /locus_tag="ACG84X_002948"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(902..904),aa:Ala,seq:tgc)
     gene            complement(957..1030)
                     /locus_tag="ACG84X_002949"
     tRNA            complement(957..1030)
                     /locus_tag="ACG84X_002949"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(994..996),aa:Pro,seq:tgg)
BASE COUNT          281 a          285 c          246 g          225 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca gtgtttttag tttttaattg
      481 cgggagcagg atttgaacct acgaccttcg ggttatgagc ccgacgagct accagactgc
      541 tccatcccgc gataatatga aaaaggagga taagggattc gaacccttgc acggttttac
      601 ccgcctgacg gttttcaaga ccgttccctt cagccggact tgggtaatcc tccatatgaa
      661 acttacaacg ccacaatgga ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
      721 gtctgctcta accaactgag ctaaaggtcc aggctcttaa aaatcgcggc ggaggggatc
      781 gaacccccga cctcccgggt atgaaccgga cgctctagcc agctgagcta caccgcgaaa
      841 aagatattca ttatttaaat gaaatggagc ctagcgggat cgaaccgctg acctcctgcg
      901 tgcaaagcag gcgctctccc agctgagcta aggccccgtg tttaaattta taattatcgg
      961 gaagacagga ttcgaacctg cgaccccttg gtcccaaacc aagtgctcta ccaagctgag
     1021 ctacttcccg tttaatt
//
LOCUS       DAZKCH010000220         1004 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.231, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000220 DAZKCH010000000
VERSION     DAZKCH010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.231"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..532)
                     /locus_tag="ACG84X_002950"
     CDS             complement(<1..532)
                     /locus_tag="ACG84X_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFP9128724.1"
                     /translation="MRISIKRWSGADWTLFTLAFFAISIVLVYTFNAPRAILYLGDII
                     NIFVLLNALSFRRRKGIYASKNEMLIVLFLLVSICSSVINLENIGLIIWGIRNNTRMF
                     IVYINCATYLTIKDYYKVFAIIEKLFWISLPLCLIERFMVTYPTGTIVGDMIGGVFWN
                     YSGCNMPLNLILCVTVT"
     gene            complement(559..>1004)
                     /locus_tag="ACG84X_002951"
     CDS             complement(559..>1004)
                     /locus_tag="ACG84X_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HFP9128725.1"
                     /translation="RITSYYYSKRKKNIIYAIMYIVSCRRMNSLGRKCGIECGENVFD
                     EGVRFYHTQGIVINGNAIIGKNCYLYGNNCIGNDGIDPKCPVIGNNVRVCVGAKIIGN
                     VKIANNVVVAAGAIVIKDCLENGAILAGVPAKIIGYVNLTKVFLE"
BASE COUNT          351 a          207 c          104 g          342 t
ORIGIN      
        1 cagtaactgt cacacacaaa attaaattca atggcatatt acaacctgaa taattccaaa
       61 aaactccacc tatcatatct cctacaattg ttccagttgg ataggtgacc atgaatcttt
      121 caattaaaca aagtggcagt gaaatccaga ataatttttc aattatagcg aatactttat
      181 agtaatcttt aattgttaaa tatgttgcac aatttatata tactatgaac atacgagtgt
      241 tatttcgtat cccccagata atcaatccta tattttctaa attaataact gagctacaaa
      301 tagaaactag taaaaacaaa actatcagca tctcattttt gctagcatat attccttttc
      361 tgcgtctaaa gctaagtgca tttaataaca caaagatatt aattatatct cccaaatata
      421 aaattgctct tggggcgtta aaagtatata caagaactat ggagattgca aaaaatgcca
      481 acgtgaacaa tgtccaatct gctcctgacc atctttttat tgaaatacgc atcgttattc
      541 accttctttc gctaaaaatt attctaaaaa tacttttgtt aaattaacat accctattat
      601 ttttgccggt acacctgcaa gaattgcacc attctctaga caatctttga taacaatagc
      661 tcctgccgca acaactacat tgttagctat ttttacatta ccaataatct ttgcacccac
      721 gcatacacgt acattatttc caattacagg acacttagga tcgattccat catttccaat
      781 acagttattc ccatataagt aacaattttt tcctattatg gcgttaccat taataacaat
      841 tccttgtgta tggtaaaatc ttacaccttc atcaaataca ttttcaccac actctatacc
      901 acattttctt cccaaactat tcattcttct gcaagacaca atatacataa tcgcataaat
      961 gatatttttc tttctctttg aataataata agatgtaatt ctca
//
LOCUS       DAZKCH010000221         1003 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.232, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000221 DAZKCH010000000
VERSION     DAZKCH010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.232"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            370..1003
                     /locus_tag="ACG84X_002952"
                     /pseudo
     CDS             370..1003
                     /locus_tag="ACG84X_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          184 g          295 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta cct
//
LOCUS       DAZKCH010000222          978 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.234, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000222 DAZKCH010000000
VERSION     DAZKCH010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.234"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(28..101)
                     /locus_tag="ACG84X_002953"
     tRNA            complement(28..101)
                     /locus_tag="ACG84X_002953"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(65..67),aa:Ile,seq:cat)
     gene            complement(656..970)
                     /locus_tag="ACG84X_002954"
     CDS             complement(656..970)
                     /locus_tag="ACG84X_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128726.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          361 a          153 c          154 g          310 t
ORIGIN      
        1 acagaacgat tcaattggct acattaatgt accctgtagg actcgaacct acgaccggac
       61 ggttatgagc cgtctgctct gaccaactga gctaagggta gtggttgttg ccacataaag
      121 ccataaacaa tcaaccagta gaatgcgtgg caacaaacct gttatcgcat atcttggagt
      181 gtgactattt atgagtgata gtgaagatat gcgtctccat atatgtatgg ttgagacaga
      241 taaacatgta tgaaaaacgt tgttaaatca acgttttttt attttggtca aggagagaaa
      301 agtagagaaa tacaaaattt tttgcattga ttttgcattc aaaaaaacat tcaaacattt
      361 agaaatcccc aatacgtatt caggaaaatc tattttaagg tttacaaaaa gaacttttgt
      421 tcgtacactc tttttgaggt gaacttttat gctgatggaa ggaaaaacac aattatggtt
      481 taagcatgtt ccttcaaata agttttttaa ttataaactc tagagaaatt aattcatcct
      541 aacataaaat aattgttcac tcaaaagttt ttctagaaca attaaaacag caggcttcac
      601 attcgctata catttgtaag aagtaataat tcctgtacta aaaggcataa ttgctttaat
      661 tattttttga cttctcttca aacacaagaa gtagttgtgt aataattgca gaaataagga
      721 ttccaataat agatataaaa tttgacatgg aaacgtctat aacattaaaa gaataaagtg
      781 ttgaagaaag taaactgatt gaaataaccc ctccgtaaaa aatagtctgt gaatataccc
      841 actttttttc agaagacgta cttcgtttgg ttctaaaacc tatccctgca tttctactct
      901 tatcaaaaaa ccaaatattt agaagtaata atattgctat tattaagata aaattactgt
      961 aaaaatccaa aagctatc
//
LOCUS       DAZKCH010000223          952 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.235, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000223 DAZKCH010000000
VERSION     DAZKCH010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.235"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..348)
                     /locus_tag="ACG84X_002955"
     CDS             complement(<1..348)
                     /locus_tag="ACG84X_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128727.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMY"
     gene            complement(355..903)
                     /locus_tag="ACG84X_002956"
     CDS             complement(355..903)
                     /locus_tag="ACG84X_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFP9128728.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
BASE COUNT          319 a          193 c           94 g          346 t
ORIGIN      
        1 atacattctt ttccagttac atttaatttt taaacaaaat tctccccaaa aaggaacttt
       61 ttctagtgaa aacttggtaa tctctttgta attaattctt gttaaagaat aattaaacac
      121 ttcattttta cttgttattt tttcattgac tataactagt tcatctggta aaaaaattaa
      181 ccaacaaaca tcgacaaaca gtaaatgata taatccattt ccacctccaa gcatattcaa
      241 tactggtgaa catgccttag aaacacgaat atagttatgg tttaaataga tattttcttt
      301 aaacattgct tgtttaaaag ccatatgctc ttgttctaaa cttttcataa acttttactc
      361 taatgcacag ctagcagcag ctgctgcaat tcctgctaca atatttacct tagctaactc
      421 tttagctgca gcttttccta attgtttttc tgcaattttt aataataaat ccgcagcttt
      481 ttcaaaatta aaagctttta atgcttcaat aaaatctccc tgcgtaccta tagcccaagc
      541 cactcctcct ccaggaagag aattaatggc tacacatcca gcatatcgtt tccaatcaac
      601 tttctccatt ctaggaacaa taatatgttc ataaaagact cttgctgctc ttccttgttc
      661 gttatcttga ctgattcgtt cacgaatagc accaaaatcc tttatatggt atacaccatg
      721 ttcgtctaaa aaaccaactg tatcaaaata aaaagttaat tcatctacta atttattctt
      781 tatttctaaa tcaactgtat tcactttttc tgtggcatac acacttgttc cagtactaac
      841 aaaagtactt aaacctaata agaaaacacc taaaacacca aatattttaa ttattctttt
      901 cataatttct cctccataaa aaataagtta ctttttaaat atcttgttta tg
//
LOCUS       DAZKCH010000224          929 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.236, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000224 DAZKCH010000000
VERSION     DAZKCH010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.236"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          328 a          143 c          132 g          326 t
ORIGIN      
        1 ataaccaaca gcaaaaaata caatgaaaaa caaacttgga actaatgtat cattaataaa
       61 tgttgaaaaa ttcagcaact cattactgta tgattttagc agcccaacca acatataccc
      121 tataaaagct aataagatgg ttaggaatcc tttagaattt ttactcattc atagacactt
      181 ccttaaataa cttttattat agaaggtatt gtaaataata atattgacaa aaagtgactc
      241 aaaataaaaa aaaccttaca ttatactgga atgaactgta ttgatagtgt acctaaaagc
      301 tctactgaca taagatcgtg taatcggtaa agtaatttta ttaattatac gggatgtaat
      361 caattagaga ataaactaat cataaaaggt acttttacat tcataattgt cgctttgaga
      421 ttctactttg gttcactatc tgacccaatt gcacattttc gatcattaca agtattggtg
      481 tcgttagaac aactaaataa aaactagcgg tagatttttc agaatctatg ctaatttctg
      541 tatggatgtt ccagtgatgg caaatttctc ttttcattgt ttttcttgtc gcatgatatg
      601 cctttttgtg ttattcagtt aaactataga aattctttcc tagacagatc ttgatcccaa
      661 attttacgtt tttgagcatc gatatagttt aaaatgacat tactcatatc taaagagttt
      721 agatttttta ggactaaaac tgtcagttgt tctttttctt ctttctgtta aagtattgtc
      781 gcgacttttc gtatacgtta agatatgtcg tgaaaaaaca agttttgtga cacaaaaaaa
      841 cgaatgactt gaggaaatca cctcaatcat tcgtttaaaa tgctatatat tctttagttt
      901 aagatacgga aattaatgcc atcgaccac
//
LOCUS       DAZKCH010000225          919 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.237, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000225 DAZKCH010000000
VERSION     DAZKCH010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.237"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..515)
                     /locus_tag="ACG84X_002957"
     CDS             complement(<1..515)
                     /locus_tag="ACG84X_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9128729.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLI"
     gene            complement(591..737)
                     /locus_tag="ACG84X_002958"
     CDS             complement(591..737)
                     /locus_tag="ACG84X_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFP9128730.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(841..>919)
                     /locus_tag="ACG84X_002959"
     CDS             complement(841..>919)
                     /locus_tag="ACG84X_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFP9128731.1"
                     /translation="NLSEIGRTAGINGLYRADYGDKSQF"
BASE COUNT          360 a          151 c           96 g          312 t
ORIGIN      
        1 aatattaaga caccaaacac aaaatgatca aatacttgat attgatgagc aacataagaa
       61 acaaataaac caattgtaag taaataaatc atgaatatag cagtaagttt agaactggac
      121 tgttcaacaa tcctatttat agctaatttt ctatataacc aaataaacat cagcaaaaac
      181 aaagaatcaa gcattatctg gaatactaca taaccatacc cttttatccc ttcaaatgaa
      241 aacatatacg tcataaccat ggaagtaata atagatctga aatcatcaat aagcatacat
      301 aatagtaatt tatttaaaag cactatatta gttttcttct tttcctttaa tataaaataa
      361 cttccgatta taggtatagc tgcggaaaca tcagtaaata attcaacaaa aaaagtgagt
      421 ggtatcaata aacatacaaa aagatatttt cttttgttaa gatcagtatt agtcatataa
      481 aataagagaa aaaagaaaaa gtttcccacg aacattctta atagataagc ttttgtatcg
      541 atagtaatca agagatcccc tcctgatttt aggatatcat aaaaaaaatt ttagttacac
      601 tttttaaata atgaaaaaac acattccact aaatttgatg ccggttttcc ttgaggtttt
      661 gttccagcac ctcctttaat ttttttaagc tcttgatctg aacattgttt agcatttagt
      721 ctattttttt cttccattac gattccccct acaaactata aatactttta tgtcactgat
      781 tcaatatacc tatttttcta atcaaaaaat tttgagacat atttaatatt ataagtatca
      841 ttaaaattga gatttatctc cataatctgc tcgatataaa ccatttattc cagcagttct
      901 tccaatttca ctcaaattt
//
LOCUS       DAZKCH010000226          911 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.239, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000226 DAZKCH010000000
VERSION     DAZKCH010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.239"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..878
                     /locus_tag="ACG84X_002960"
     CDS             <1..878
                     /locus_tag="ACG84X_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9128732.1"
                     /translation="SLNQPLPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENR
                     QLNPLRDYFLRYPRKVREQVRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRA
                     FTNHRIQVMKTFKKRDRRSKHLKKYWRLLQKNAWELKGQHRYWRPSFRDHLTEAEIVD
                     RLLSYDDSLKRGYEVYQDFLSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRT
                     EIKRALRVPYSNGPIECLNNHIKVLKRIAYGFRNFQNYQERIFLYRGKYFKKTKNTTQ
                     LTKARTTTRLDKIAV"
BASE COUNT          291 a          202 c          184 g          234 t
ORIGIN      
        1 tttctttgaa ccagccgtta ccagaagtgg tgtgtttcga tgaattcaaa tcggtgaaaa
       61 acgtctcggg agccatgagc tttgtcatga tggacggcaa gacccatcaa ctgattgata
      121 ttgtggaaaa tcggcaacta aatcctttac gcgactattt cttgcgctac cctagaaaag
      181 tccgtgaaca agtacgtcta gtggtttcag atttctatac accctatcgc acattggtga
      241 aagagtgctt tccgaatgcc cgaatcgtcg ccgatcgctt tcatattagc caacacatcg
      301 gtcgggcctt taccaaccac cgaattcaag taatgaagac ctttaaaaaa agggatcgtc
      361 ggtcgaagca cttaaagaaa tactggagac tacttcaaaa gaatgcgtgg gaattgaaag
      421 gtcagcatcg ctactggcgt ccgtcatttc gagatcatct gacagaagca gagatagtcg
      481 atcggctatt atcttatgat gactccttaa agcgaggcta cgaagtctac caggattttc
      541 tttccgctat cagaagacaa gatgttcctg aattcgtcgc gctcctaaaa gaagactaca
      601 aggagttgcc agagcactac caaccagtgt tcacgacctt caagaaatat cgaacagaaa
      661 tcaaacgagc gttgcgagtt ccctattcca acggccctat agaatgtttg aacaaccata
      721 tcaaagtact aaaacgaatt gcctatggct ttagaaactt tcaaaactac caagaacgaa
      781 tctttttata tcgaggaaaa tattttaaga aaactaagaa cactacccaa ctgactaaag
      841 ctagaacaac aacacggcta gacaagatag ctgtctagcc gtgtgagtat ctcgattatt
      901 ctattgaatt t
//
LOCUS       DAZKCH010000227          909 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.240, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000227 DAZKCH010000000
VERSION     DAZKCH010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.240"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>909
                     /locus_tag="ACG84X_002961"
     CDS             <1..>909
                     /locus_tag="ACG84X_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-54"
                     /protein_id="HFP9128733.1"
                     /translation="LFQNHISIEESMSQLRDRILKECAGSSEYNYLESDEFIALRNYV
                     VNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFRMKNDKQKLL
                     ANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITASAIARETNKL
                     LNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQMYEKIESNVI
                     GDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLSQKKNVIVSC
                     LSGEGISEKVKDILKRYLDNQVEILI"
BASE COUNT          330 a          102 c          172 g          305 t
ORIGIN      
        1 actttttcaa aatcacattt caattgaaga aagcatgagt caattaagag atagaatact
       61 taaagagtgt gcaggttctt ctgagtataa ttatttagaa agtgacgaat ttatagcatt
      121 aagaaactat gttgttaata aaatatcacc aattattgat tcgacaggtc tatgtttatt
      181 agatgaattc ttggcggata tcagtctatt tataatgttt attgatgtaa ttgaagaaac
      241 atcaagaaat tttttgctgt ctaagttcag aaaatttcgt atgaaaaatg ataaacaaaa
      301 attattggca aatgagattt ggagtagttt agaagtcgaa gaaagtaaac aagaactttt
      361 gttgaaatgg atactttttc ttgtaaagaa gttctatgtg aaaataccag aaacccattg
      421 tctgatagtt atgcacggta aaataacagc ttctgcgatc gcaagggaaa caaataagtt
      481 gctgaataca tatgtttatg aggctttcga tatgccaatt gaaggtgaga ctagtgactt
      541 aattaaccta atcaacaatt tttgtaaaag tatagatacg acgaatggac tcattctgct
      601 agttgatatg ggatcattgg aacaaatgta tgaaaaaatt gaatccaatg taataggtga
      661 tttggtaatt ttaaacaatg tttctacagc tttagcgatt gaatgtggga ttcaagtttg
      721 ccaaaaaaag ccaattagtc atttttacca gatggatttt gattcgtttc aagttaaagt
      781 tcagtattat aaaggattat cacaaaagaa aaatgtaata gtatcttgtc tctctggtga
      841 ggggatttct gaaaaagtta aggatatttt aaaacggtat ctcgataatc aagtggagat
      901 tttgatttt
//
LOCUS       DAZKCH010000228          894 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.241, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000228 DAZKCH010000000
VERSION     DAZKCH010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.241"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            252..875
                     /locus_tag="ACG84X_002962"
     CDS             252..875
                     /locus_tag="ACG84X_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9128734.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
BASE COUNT          329 a          129 c          167 g          269 t
ORIGIN      
        1 aactaatgtc cttatttttg tgttcacatt tctgttacct aagaaatact taaaggaggt
       61 gatgtagcca gcaacgacta caacttgaac ccgctatcta cagtttattt gttgtttctt
      121 ttgggtatac tctaatggta caaatccata tttgcttaaa gcgttgattt ttcagcggtt
      181 tttctttatt gcaaagtgta ccctaagacc tgtatactaa tagtaaatag attggatagg
      241 aatgatggca aatgtattta gcttatttaa gagtttcttc cgacgatcaa agtttagctc
      301 ggcaacataa gctaattgaa aattggtcag tcaaaaataa tattgctgaa gacgatttaa
      361 aaattttcga ggaaaaagtc tctggaaaaa atattgaaaa cagaccagag ctgcaagagc
      421 ttatttcttt catacgtgaa cgagatacga ttattattcc tagtcttgat cgattagcaa
      481 gaaatagtaa agatacaaaa gacttacttc aattgtttcg tagtaaaggt gcttctattg
      541 aaatattaga cctaccgtcg tttaatgggg taactgaccc tgcattaaga gacttgctaa
      601 caaatttagt catagaagtg tttagctatg ttgctgaaaa cgaacggaaa aaaatcaaag
      661 agcgtcaaaa acaaggcatt gaaattgcaa agaaaaatgg tcgttatact ggtaaaaaga
      721 ttcaatacca tgccaatgca acaggaaaaa acaaattgat ttacgatgaa attgttgatg
      781 gtctgaagaa aaaagaaact atttctaaaa tagcaaagaa cgcaggagtt acaagaaaaa
      841 ccgtttatcg agtaaaaaga gatttaggaa tgtaatatgt tccagttaga aaga
//
LOCUS       DAZKCH010000229          893 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.242, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000229 DAZKCH010000000
VERSION     DAZKCH010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.242"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..272)
                     /locus_tag="ACG84X_002963"
     CDS             complement(<1..272)
                     /locus_tag="ACG84X_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFP9128735.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSD"
     gene            complement(262..>893)
                     /locus_tag="ACG84X_002964"
     CDS             complement(262..>893)
                     /locus_tag="ACG84X_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFP9128736.1"
                     /translation="INTWNNIKDSFWNIVTGIVNSAENAWTNLKNGVSNAINRVKEIF
                     NSLREVNLFEIGKNIIDGLINGVKEKWNALKDTIKGIAGNIKNWIKGALDIHSPSRWM
                     RDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTPSVQPVVNGISHLPITQTKQNISAS
                     ETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQMKRDAGAVGGTLYAT"
BASE COUNT          274 a          175 c          108 g          336 t
ORIGIN      
        1 aaatcactat aagacgacat atctaaccat tcagtgattc gatcttccca ctcctgcacc
       61 atatcaattg aaggtgcttt atagtaacac tcaatctttc tagtcacatt tttgtaatag
      121 cctttatcaa taatgataga atcatttcct tctcgctctc tcaattcaat tactcgacta
      181 gctgaaacag aagcaggcct gttttgaata tacacattaa attcagaaga ataatgttga
      241 ttaataaaaa attgtcctct cttaagttgc atataatgtt cctcctactg caccagcatc
      301 tcgtttcatt tgtcttgtca attctgtttt aatttttgtg gtaatcttcc gaaccattga
      361 atcaggtaaa tctccataaa catttaaatg taaatgaatt tcttttgttt cactagcaga
      421 tatattttgc tttgtttgtg taattggtag gtgacttatt ccatttacta caggttgaac
      481 agacggtgtt tttactaaat ttgtcatggt ttgatctaac ttactttgct ctttatcaat
      541 accaacgata ataccttgaa caatattttt accaaccata tcacgcatcc atcttgatgg
      601 agaatgaata tctaaagctc ctttaatcca atttttgata ttacctgcaa tacctttgat
      661 agtatctttc aaagcattcc acttttcttt tacaccattt ataagtccat caatgatgtt
      721 cttgccaatt tcaaataaat tgacttccct taacgaatta aagatttctt ttacccgatt
      781 aatagcattt gaaacaccat tttttagatt tgtccatgca ttttcagcag aattaacaat
      841 tccagtaaca atattccaga aagagtcctt aatgttattc catgtattaa tca
//
LOCUS       DAZKCH010000230          890 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.243, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000230 DAZKCH010000000
VERSION     DAZKCH010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.243"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..888
                     /locus_tag="ACG84X_002965"
     CDS             <1..888
                     /locus_tag="ACG84X_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFP9128737.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DAZKCH010000231          868 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.244, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000231 DAZKCH010000000
VERSION     DAZKCH010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.244"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..>868
                     /gene="bsh"
                     /locus_tag="ACG84X_002966"
     CDS             4..>868
                     /gene="bsh"
                     /locus_tag="ACG84X_002966"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFP9128738.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRT"
BASE COUNT          291 a          118 c          159 g          300 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagtcact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgatgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacat
//
LOCUS       DAZKCH010000232          852 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.245, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000232 DAZKCH010000000
VERSION     DAZKCH010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.245"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            90..563
                     /locus_tag="ACG84X_002967"
     CDS             90..563
                     /locus_tag="ACG84X_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFP9128739.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            572..799
                     /locus_tag="ACG84X_002968"
     CDS             572..799
                     /locus_tag="ACG84X_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128740.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          290 a          125 c          150 g          287 t
ORIGIN      
        1 atatttttat tgtttttcga taaaaaatag ttgttttaca ataattattc tgctatattt
       61 tagctatcaa agataaaaga gggataaaaa tgaaatttaa aacattgcta ttaaaatttg
      121 tcgttttagg tataagtgcc gtatttattt tgttcggcgt acttttttat actcagatcg
      181 ctacaagcga aaaaggattc aattttgatt ggcagaccac attatttgtt tctgtcattt
      241 actttgccct tctcctaggg atcgttattg cttatttctt attgaaacta ttgaaaaaaa
      301 tcgaagataa ccaagctttt tccactcaaa gcttaaacat actaaaaaaa atcgaacgaa
      361 ccattttgtt tattggtttc gccttttttg gcttacttcc taaatttatg aaagtagcgg
      421 atttagacga tgctccaggt ttgatgttgg taggaatcgc tgtcgtattc attccttttg
      481 cagtatacac attaacaagc gtgctggaaa aactgcttga acatgcgatt ttacttaaga
      541 cagatcatga tttgacagtg tgaggtgcga catggcaatt atcgttaatt tagatgtagt
      601 attagctcaa aaaaaaatga gtgtgactga attgagtgag aaagtgggca ttacgatggc
      661 aaacatctct attctaaaaa atggaaaagc aaaagccatc cgtttttcca ctctcgaaaa
      721 aatctgccaa gttttggagt gtcaaccagg tgatttgttg acctataaaa atgactcgaa
      781 tactatacca gaagaataaa ataaagtaga acaaacagta aataaaaaat aatctgaatg
      841 atagatgtgt ga
//
LOCUS       DAZKCH010000233          814 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.246, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000233 DAZKCH010000000
VERSION     DAZKCH010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.246"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            134..307
                     /locus_tag="ACG84X_002969"
     CDS             134..307
                     /locus_tag="ACG84X_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128741.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
BASE COUNT          274 a          131 c          103 g          306 t
ORIGIN      
        1 ttcggagaat taaaaaatac aataaataac tttagttact ttaatgcgtt cttactttat
       61 ttttatatta tcatttttct tattcacttc tttggtttat actattctta taaataaaaa
      121 cgaggtatgt cctatgatga aaagattgta ctattcattg atcataacga ttggctattt
      181 gattgtatca aatctaggaa atatggtatt tggtatcagt aaagaattca gttggactac
      241 tacattatgg gaatctctat tctttttcat cttcgtattt ttgttacaaa attatcgaaa
      301 aaaataaaca tgtgccatct atctgttggc acatgtttta ggatttatgg tactttttat
      361 tcggcaatcc attttatttt tctacttctt cttaatacct ctaacacttt tgatttataa
      421 actaatccaa tgcatctact tgcgcttatt aagctatttc agctagatag taccacccca
      481 tgcgtcaatg cttgattttc cttttgtata acattgtata agcaataaag gacaaataag
      541 tggtgattac accaaaccat tgaataagaa aaattctgat acgtaaataa acatgaactt
      601 gaaaaaatta atgaatcggt tagctactac gtagttgtct tttttctcat acagttctgt
      661 taacttacac ttctcttcgc tagataataa aaaatcctcc aactgtattg tccaatataa
      721 tcccaggcat ctaaactagc attatagaag agacacacat agaatctaaa ataactggtt
      781 ttaaatgttt cttacaatca aaaaaagctg ttaa
//
LOCUS       DAZKCH010000234          798 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.247, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000234 DAZKCH010000000
VERSION     DAZKCH010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.247"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(57..>798)
                     /locus_tag="ACG84X_002970"
     CDS             complement(57..>798)
                     /locus_tag="ACG84X_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFP9128742.1"
                     /translation="QVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLV
                     YFSFGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRF
                     TIWKAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQ
                     VLVSSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHV
                     LFNKRDVISIVFWYYLGSISYLYLKKEN"
BASE COUNT          305 a          140 c           95 g          258 t
ORIGIN      
        1 catttaatat attaatcaaa tgtaaaggag tccaagcaat gaaagctgtc ttcatattaa
       61 ttctcctttt ttaaatacaa gtaagaaatg cttcccaaat aataccagaa aacaattgaa
      121 atgacatcgc gcttattgaa aagtacatga gcctccacca tttcatctat aaaaatagat
      181 agtataaaaa ttaaaacaat accaagaaac gcataattca ctttacttct aaaaaatgtt
      241 ttgagtaaac taaagatatt taacacatag aaagcataga tacatataaa agcaattata
      301 ccacttgata caagtacttg aagaaatcca ttatgcatgt ttccatgtgc tctttttagt
      361 tcattcacat ctgtagtatc aagatctact tttttcaaaa attttgcatc gctattccca
      421 tagaaatcgg tctctccata accaaataac aaagttggtc ttataacttt aagcgcagct
      481 ttccaaatcg taaaacgacc agctgaaatt tcggagttat cactagaatg ctgtaatatt
      541 acttcttttt ctggaagtgg agttttatct gattcatttg actctataac ttctactttt
      601 ctatcaatcg atacaggaat tgttgctaaa aaatccttag cataattagt accaaaagaa
      661 aaatatacca atagaactaa taatatgctt accatccatt tgatttttac aggtagtact
      721 tctctaatgc tctttctaaa ttttgaattg gcaaacaaca aaagaaataa tactaaaaaa
      781 gaacaaatta ctacctgg
//
LOCUS       DAZKCH010000235          791 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.248, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000235 DAZKCH010000000
VERSION     DAZKCH010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.248"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            366..764
                     /gene="spxA"
                     /locus_tag="ACG84X_002971"
     CDS             366..764
                     /gene="spxA"
                     /locus_tag="ACG84X_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFP9128743.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          298 a          109 c          139 g          245 t
ORIGIN      
        1 ataaagaaca gtattattta aaatgacaga aaacattact attaaagaaa taaaaaacat
       61 aaaaaatctt aagaaatcgg tttcatttag cttttgagat aaaataatag tacagtttta
      121 tacgctgttt catatgttta gaaaatttga attagatttg aaaactctaa tttttaaatg
      181 ataaaaaaag cgagaatgct ggttttactg tatattaacc ttagataact ttcatttttt
      241 taaaaaaatt atgaaaaaaa ggtagctatt taaaagttga ttatgtataa tagaaacaga
      301 tgggagatta ttatgatctt ctgttacaaa aaagtgattc ttatcacgaa aaggagtggt
      361 gcacgttgtt aacattatat acttccccaa gttgtacttc ctgcagaaag gctcgtgcgt
      421 ggttgcaaga acatcagatt ccatttgttg aacgtaatat tttttcagaa ccattgaaca
      481 gttctgaatt aaaagcgatt ttacaaatga cagaagacgg aacagaagaa atcatctcga
      541 cacgttccaa agtattccaa aaactgaaca tggatttaga tgatctgccg ttacaagaat
      601 tattggaact tgtgcaaaac aatcctggat tgcttcgccg tccaatcatg attgatgata
      661 aacgtctgca agttggtttt aatgaagatg aaattcgtcg gttcctaccg cgcgatgtac
      721 gacaattaga attacgtcaa gcacaattga tggctggatt atagaaggat aatacgaaac
      781 ttggaaaaga c
//
LOCUS       DAZKCH010000236          774 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.250, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000236 DAZKCH010000000
VERSION     DAZKCH010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.250"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(109..>774)
                     /locus_tag="ACG84X_002972"
     CDS             complement(109..>774)
                     /locus_tag="ACG84X_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HFP9128744.1"
                     /translation="RRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQ
                     EQPLEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYS
                     LTDVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVH
                     QYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSG
                     EAA"
BASE COUNT          213 a          179 c          150 g          232 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt
      421 atcaaattcc tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat
      481 ccgtccaaag gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat
      541 aatttctcga ttaaacaaat caagtattaa gcagatataa tgccactttt tccccacgcg
      601 aacataagta agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc
      661 taatacattc gctgttttcg cttcattaca agctgttcgt tgccctttaa aatgagcgat
      721 cgtataggta gatgtcaatc cgcggcgttt catgattcga ccgattcggc gccg
//
LOCUS       DAZKCH010000237          764 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.251, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000237 DAZKCH010000000
VERSION     DAZKCH010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.251"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            216..428
                     /locus_tag="ACG84X_002973"
     CDS             216..428
                     /locus_tag="ACG84X_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128745.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAA
                     AVVITAVAKASDSILAWLKFKKEQKK"
     gene            590..>764
                     /locus_tag="ACG84X_002974"
     CDS             590..>764
                     /locus_tag="ACG84X_002974"
                     /inference="COORDINATES: protein motif:HMM:NF015824.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFP9128746.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSE
                     IFENISDPLPEEDS"
BASE COUNT          267 a          121 c          126 g          250 t
ORIGIN      
        1 gattcatcgt cattcctcct gctatctttt tctattattc taccttattt gatagtagat
       61 ttaaaacttt gcaacagaac cctaaaaaca ctatatattc cgaaaagtga gtatctccat
      121 tcataaaata atcaacatat ttaaaaaatc taattagctt ttttagtcaa tctaaagttc
      181 tttattctat gatataatgt tactgtagaa agtttgtggc ggtttggcaa atccaattga
      241 aggagcgtgg tgcctatggg cttattagct tatcggacgt actctgtaga aaggaaatgc
      301 ctgatttgtt ctcattggat caaatcattg ctattatcgg agcagcagca gtagttatta
      361 ctgccgtagc gaaagctagc gattcgattt tagcttggtt aaagttcaaa aaagaacaaa
      421 aaaaatagag ccgtctcaac ttttggcgag gtagacgagc tctaaagctt tatttacatg
      481 ccatccgctt tgaacggact acactgggca tgtgacagca tgccctttca tttatattat
      541 atctcattct tttatataat gaaagtaaat aaatcatgga ggataaaata tggataaatt
      601 taatagatta acattaataa atcagtttga aattttaaaa gctttaaatc ctaacgaaga
      661 aaaatactat gctgaaaaaa tagaaatact aacagaaggt tacgaatatc actatagtga
      721 aatatttgaa aatatttctg atccattgcc agaagaagat tcgc
//
LOCUS       DAZKCH010000238          758 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.252, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000238 DAZKCH010000000
VERSION     DAZKCH010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.252"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            37..>758
                     /locus_tag="ACG84X_002975"
     CDS             37..>758
                     /locus_tag="ACG84X_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128747.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGP"
BASE COUNT          247 a          101 c          102 g          308 t
ORIGIN      
        1 aaaaaataaa tgatactata tgtaatataa aaaaacatga ggtggtatat gaatttgaaa
       61 aaaatttttt ctgtaaaaat atttatagtt tatgcatttg ttagtttatt atatttattt
      121 ccagcattta aaaacatgga aatatttggc ttttatgata cggcatttca cattaatcgt
      181 gcgttaagtt tagaatctat ttttagctcc cctattaatt ttgaaacgtt tagatcatat
      241 ggcatgcaag taaataattt ttacccatgg ttaactctat atcctttatt tttattgatc
      301 aagtttacta atttagcaat aggctataac ctttttcttt atattgttac gctcattact
      361 ctatttatat gtcattatgt aatgtatgaa attaccaaaa aacatgttac tagctccttt
      421 ttcgctatta tatatacaac atcttctttt aggagtgtag aaatatttct tcgaggggca
      481 atgggggaat tactcgcaat gtcaatactt cctcttattt tactcgggtt tataaagctt
      541 tacgactcaa aaaaagaatc ttgggttatg ttggcgatta gcatgacttt attaatttac
      601 actcatgttc tttctgtagc tatgactatg gtaatgatta taattgcttt aattattcaa
      661 ttttatcgga aaaagaaaat agaaatcttc ttaattatta aattaataaa agctgctata
      721 gttactttac ttctttcact agcgtttata ggtcctat
//
LOCUS       DAZKCH010000239          752 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.253, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000239 DAZKCH010000000
VERSION     DAZKCH010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.253"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>752
                     /locus_tag="ACG84X_002976"
     CDS             <1..>752
                     /locus_tag="ACG84X_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFP9128748.1"
                     /translation="FKLYQIIIPFFMRTLMIYQMGMEYAGLNNLFTSIFQMLNLAELG
                     IGAALTVSMYKPIAEDNRKEICALLNAYKKYFSIIGWIVFTLGLLCIPFLRFLVKGSI
                     PGNLNMTVLYLMYLINTVLSYWLFSYRKSLIYAHQRNDVINVSMLITFTFQFVMQAYV
                     LIFLKNYYLYLLASILGQIVLNLMCAVVSQKMYPDYTPVGELEKETIDDIIKKVKGLV
                     TNKVGGTILRSSDSIIISSFLGLSVLAIYQNY"
BASE COUNT          239 a           90 c          129 g          294 t
ORIGIN      
        1 ttttaagtta tatcagatta tcattccctt ttttatgcgt acacttatga tttatcagat
       61 gggaatggag tatgctggat tgaacaacct gttcacatct atatttcaaa tgttaaattt
      121 agcggaattg ggaataggtg ctgcactaac tgtaagtatg tataaaccta tagcagaaga
      181 caatagaaaa gagatttgtg ctttactgaa cgcatataaa aagtactttt caattattgg
      241 atggatagtg tttacattag gattgttatg cattcctttt ttgagatttt tagttaaagg
      301 ttcgattcct ggaaatttaa atatgacagt tttgtattta atgtatttga taaatactgt
      361 tttgtcgtat tggttatttt catatagaaa gagtctaata tatgcacatc aaagaaatga
      421 tgtaattaac gtgtctatgc taattacttt tacattccaa tttgtaatgc aggcatatgt
      481 tctgattttc ttaaaaaatt actatttgta tttattggct tctattttgg gacaaatagt
      541 tcttaactta atgtgtgctg ttgtttctca aaagatgtat cctgattata ctcctgttgg
      601 tgagttagag aaagaaacta ttgacgatat tataaaaaaa gtaaaaggat tagttacaaa
      661 caaggtaggc ggtacaatat tacgatcttc agattcaatt attatttcat ctttcttagg
      721 tctttcagta cttgcgattt atcagaatta tt
//
LOCUS       DAZKCH010000240          746 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.254, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000240 DAZKCH010000000
VERSION     DAZKCH010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.254"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..473
                     /locus_tag="ACG84X_002977"
     CDS             <1..473
                     /locus_tag="ACG84X_002977"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9128749.1"
                     /translation="KQKNQSYLLEIFLEILKMNSDSYLILVGEGSLRNKLKAKAVELD
                     IEKRVKFLGERNDIPELLSVMDVFVMPSLYEGLPMVGLEAQAAKLKLVLADTISKDTK
                     LTNNVDFVSLDETPQEWAKKVIKEPYANKITQELKSYDVSYTTEQMESIYSRDH"
     gene            506..>746
                     /locus_tag="ACG84X_002978"
     CDS             506..>746
                     /locus_tag="ACG84X_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFP9128750.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKR"
BASE COUNT          298 a           76 c          134 g          238 t
ORIGIN      
        1 agaaacaaaa aaatcaatct tatttgttag agattttttt agaaatacta aaaatgaatt
       61 ctgattctta cttgatttta gtaggtgaag ggtcacttag aaataaactg aaagccaaag
      121 cagtagaatt ggatatagag aaaagagtaa aatttttagg agaaagaaac gatattcccg
      181 agttattatc tgtgatggat gtttttgtaa tgccttctct ttatgaaggt ctgccaatgg
      241 ttggattaga agcacaagca gcaaaattaa aattagtctt agcagatact atttccaaag
      301 atacaaagtt aacaaataat gtggattttg tatcattaga tgaaacacca caagaatggg
      361 caaaaaaagt aataaaagag ccgtatgcta ataaaataac acaagaacta aagagttatg
      421 atgtttcgta cactactgaa caaatggaga gtatatatag tagagatcat taaaaatgtt
      481 caagatattt taggagtgat tatttttgaa aatatgttat ttgatattgg catacaatga
      541 tattggcaac ttaaagagat tggtcaatcg attgaacgaa aatgcagttt ttattattca
      601 tatagataaa aaaactgata tagaaccatt tattgaagca tttaaatcat atgataatgt
      661 tgaattttta tgtaataaaa accgtgttaa aatttattgg ggtggttttt ccattgtaca
      721 agcagaaatc aatttagtaa agagag
//
LOCUS       DAZKCH010000241          739 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.255, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000241 DAZKCH010000000
VERSION     DAZKCH010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.255"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..624
                     /locus_tag="ACG84X_002979"
     CDS             85..624
                     /locus_tag="ACG84X_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128751.1"
                     /translation="MWSLVGIVLIIFTVTAATEANYSHKIQSYKGRLVMTKKDVTRYT
                     SSRTGGLYDYAPLDALKYKDHLKKHEVKVGDRWENASHKAYNSKIVYTVEDADEQNIT
                     LPVFNYWGTVVKVNGKKSTIENDNGLVSIKGTGKRTIVEVSSTYPTTMILSLLISSIT
                     FIFLFTRYLIRCCGEMKID"
BASE COUNT          279 a           93 c          139 g          228 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagag
//
LOCUS       DAZKCH010000242          731 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.256, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000242 DAZKCH010000000
VERSION     DAZKCH010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.256"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(333..446)
                     /locus_tag="ACG84X_002980"
                     /pseudo
     CDS             complement(333..446)
                     /locus_tag="ACG84X_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          268 a          115 c          112 g          236 t
ORIGIN      
        1 tctttttcgt tgctttgctc ataaaaatct gcatattcat cactaatatt ttttctaata
       61 aattcttcca tcataaagat cacctcgaaa agagtatacg aacaaacgtt ctttttgtaa
      121 aggtggaatt tattatacta aataaatagg tgaacaagta cttgtgccaa attatgtgcc
      181 aaaaaaaatc gaatttaata aaacacaaac aaaaagaaat cctattatga taacatttct
      241 tataataaca aacacaacag aagacgtgta atagttagtc aggaacgtac aaataacccc
      301 tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt ttctaaactg
      361 ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag taaaatagat
      421 gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga aaaattgatt
      481 actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca atagattcga
      541 attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata tcgttcttaa
      601 ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg gagatgactt
      661 tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt tcaaagtacc
      721 atataaaaaa a
//
LOCUS       DAZKCH010000243          725 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.257, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000243 DAZKCH010000000
VERSION     DAZKCH010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.257"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>725
                     /locus_tag="ACG84X_002981"
     CDS             <1..>725
                     /locus_tag="ACG84X_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HFP9128752.1"
                     /translation="GFTKQSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSY
                     PLVGPATWDGKVYVQNLFNAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGF
                     KACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESL
                     IGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGW
                     KVIQNPRYDQLVVGAIINWARGG"
BASE COUNT          226 a          112 c          179 g          208 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga catttacaaa tggacaatgg atgggcgtag tacaacctac gacggttgat
      301 ggatttaagg cctgtactga tccaagacaa gcagcatatg cttttgaacg aaactatgaa
      361 cgtccggcag cgacacatcc tgaacgtcaa gattatgcag ttaactggta taacaaattt
      421 aaagatttaa aaccaggagg agctactgga gaagcaggac taaaacattt agagtctttg
      481 attggacaac gaattggcaa tggtcagtgt tatggcttgt ctgcagaata ttcaggatat
      541 ctgggtggtt gtggcatggg tgctggaaca aaatatggtt taactcatgt gataggaaat
      601 acttctgcag catctgatat tggtattgcc tatgattggt ctgctgttgg ttggaaagtg
      661 attcaaaacc ctagatatga tcaattagta gttggtgcaa ttattaattg ggcaagaggt
      721 ggaca
//
LOCUS       DAZKCH010000244          719 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.258, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000244 DAZKCH010000000
VERSION     DAZKCH010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.258"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(334..>719)
                     /locus_tag="ACG84X_002982"
     CDS             complement(334..>719)
                     /locus_tag="ACG84X_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TetR-like C-terminal domain-containing protein"
                     /protein_id="HFP9128753.1"
                     /translation="QLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLFI
                     LNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVES
                     NYKYSKKELLELLQKLNDHIEKIMP"
BASE COUNT          247 a          101 c          125 g          246 t
ORIGIN      
        1 tgattcccct tgaaaatgaa ttgaggtaaa cgagaagaat tcaataaact ggatgataaa
       61 aatataatat gactataaat tggttacagc ttcaacctat aagttgtaat aaattagcct
      121 aaaagtaatt tattaatgat gaggtgaatt tgattggtac aacaagatat atcacttaga
      181 gagggagaag cagcactaca aactactttt caataagtag gaattataga aattttactc
      241 aaaaaatctt cagtaaacaa tttggctaaa taagattcag ttgttatacg agaaggttac
      301 ggttcttctt aactaagctt agtatgtttt tattcaaggc atgattttct ctatgtgatc
      361 attcagtttc tgtaagagtt ctaataattc ttttttggag tacttgtaat tgctttctac
      421 ccaccgattg agaacggata gacaaccttg gacgtggtac gtagtaaaga atctcatttc
      481 ttctgtgata atcgttttct tgtcttcata tagccatatg ttcagatagt tttcttcaat
      541 aacttgttta actttcttct gaaacgaaat atcaccatgg ttgaggataa ataagcgata
      601 taaaaaagta tttgcgtaaa catagtcaat caagcgagtg tatagttcct catagctatg
      661 ggctggatca taagagagaa tttcatttag atcccgaaaa aagttgcttt ctaattgat
//
LOCUS       DAZKCH010000245          712 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.259, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000245 DAZKCH010000000
VERSION     DAZKCH010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.259"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..482)
                     /locus_tag="ACG84X_002983"
     CDS             complement(<1..482)
                     /locus_tag="ACG84X_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9128754.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     "
BASE COUNT          225 a          132 c          103 g          252 t
ORIGIN      
        1 tccgcaatgt acatcgcgga tttactatat acagaaatag aaggtgggac atctaaatag
       61 atgacgtcaa actcatcaaa taatggttct agcttttctt tcatatattt gaattgggat
      121 aatgaatcat tatattggtc tttgatccaa tcatcataca tttcaaagga catgtctgct
      181 ggaagtatat agaggttatt gattacttta tagacagcct ctttaggtgg aagattgttt
      241 atcaacacgt cagtcacagt attttcgtaa acaatcggtt caccttctcc gcctccttct
      301 tcgttagtga agttcatatg cgttaagttc atcacatcag aagtatttcc ttgcatatcc
      361 aagtcaatta tcaaggttct ttttccttca ttaactgctg attcaaaccc taacatttgc
      421 gcgcacgtac ttttacctac gccaccttta aaattaccga ttacatattt cttcgctacc
      481 acgttcctac ctcttttctt ttagcaatat tcatttgata ctattataac atatttattt
      541 ttagttacta ccaaaaaaaa gatatatatg tactacctta taattaataa gtaaaaggta
      601 gtacataaat aaggaaaagc tgaaatatat tgatttatag ctttcctcaa agtaatgacg
      661 ttatttaatt tatcgagaag cagagaatac tcgcgacttt agtcatgtag ac
//
LOCUS       DAZKCH010000246          709 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.260, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000246 DAZKCH010000000
VERSION     DAZKCH010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..709
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.260"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..600
                     /locus_tag="ACG84X_002984"
     CDS             <1..600
                     /locus_tag="ACG84X_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9128755.1"
                     /translation="TMKKEFPIPISWTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGV
                     GGGALQEGRFIEGFSHPEMGHMLVVPHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGK
                     KGQEVAEDDPYWEIEASYIAQCAYNTTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKL
                     VNGYVETPELSKYIVTPALEDNAGTLGCLALAREAVLHS"
BASE COUNT          200 a          140 c          180 g          189 t
ORIGIN      
        1 accatgaaaa aagaatttcc gatcccgatt tcttggacaa cagatgtcaa tgcggctgcc
       61 tatggtgagt atgtcttcgg cagtggcaaa ggattgagca gtgtcgttta ctatacgatc
      121 ggtacgggtg ttggcggcgg tgccttacaa gaagggcgct ttatcgaagg gtttagtcat
      181 ccagaaatgg ggcatatgct cgtcgtccct catccaaaag atgactttgc tggcagctgt
      241 ccatttcatg gcaactgttt agaagggatg gccgctggac ccgccatcga aaaacgctta
      301 gggaaaaaag gacaagaggt tgcagaagat gatccttatt gggaaatcga agcctcctat
      361 attgctcaat gtgcctacaa tacaaccttg atgttttctc cagatgtgat catttttggc
      421 ggtggtgtga tgaaacaacg ccatatgctg caaaacgtcc acgacgcatt tgcaaaattg
      481 gtcaatgggt atgtcgaaac acctgagtta agcaaatata tcgtgacccc agcattagaa
      541 gacaacgctg gaacgctcgg ttgtttggca ttggctcgag aagcggtctt acattcataa
      601 acgaaaaaag gctcttcgac atttagtgtt ggtagagaaa gatacaactg aaaatttagt
      661 cataaccagt taggcagagt gcttaactgg tttttgtttt acttggaag
//
LOCUS       DAZKCH010000247          696 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.261, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000247 DAZKCH010000000
VERSION     DAZKCH010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.261"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            74..403
                     /locus_tag="ACG84X_002985"
     CDS             74..403
                     /locus_tag="ACG84X_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFP9128756.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            393..679
                     /locus_tag="ACG84X_002986"
                     /pseudo
     CDS             393..679
                     /locus_tag="ACG84X_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT          264 a           77 c          133 g          222 t
ORIGIN      
        1 cttgtaaata cattatctcg tggtataatg tatttactaa gtaattacat actgttagaa
       61 atgagggatt taaatgatta caaaaacaag aaaacaaggc aattcaatca tgttgacagt
      121 acctaaagat tttaatgttc ctaatggagt cgaagttgaa gcaaagttgg tagagaatgg
      181 tattctttat gaatttgttg aaccacaaaa agaattttat gattttagcg aagatatttt
      241 gtctgatata attgcagaag gctacgataa agatgagatt cttgtagaat ttaagaatag
      301 aaaaaacaaa atgcattctt cctttagaga tattgctgaa gatacactta ctaattctaa
      361 agtaatgact aaagaggagt tggcaacaga aattggctta tgaaatcgtt ccttcaaaac
      421 atgtcattaa gtatttaaaa agctaaaaga gaagccattg aaagaaaaat ttttgaattt
      481 aatttatgat gaaattgcga ttgatccata taagggtgaa caaaaaactg gggatttatc
      541 aggtatttgg tctagtgggt tcaaatatgc gggcacaaca tatagagtag cttacgagat
      601 tatagaaaac aaggttattc cagtattgtt atgtggaacg catgaaaact tttatgaaca
      661 gttgaaaaaa ttaatctagt gatttgttgt cgttct
//
LOCUS       DAZKCH010000248          672 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.262, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000248 DAZKCH010000000
VERSION     DAZKCH010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.262"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..362
                     /locus_tag="ACG84X_002987"
     CDS             <1..362
                     /locus_tag="ACG84X_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFP9128757.1"
                     /translation="FPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIEIHLDYFGRV
                     PTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFFENVVTGKEN
                     WNDLYHANEVLKIAEEK"
     gene            363..>672
                     /locus_tag="ACG84X_002988"
     CDS             363..>672
                     /locus_tag="ACG84X_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFP9128758.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     N"
BASE COUNT          267 a           74 c          123 g          208 t
ORIGIN      
        1 gtttccctaa atcagtaaaa aaacagtttg gtaaatattc gaatcttgaa attaacagta
       61 atgatttagc aacatatata ttgagatacg atgataaaat tatagaaatt catttagatt
      121 attttggaag agttcctaca agaaaatttc aattgtttac tttagatgaa tgtatcaatg
      181 ttgacttatt aaataataaa ataagttttg aagaaaacat tgttaaagaa atgcctgaat
      241 ctgctaatga tatgtatgag aaggagttga aatatttctt tgaaaacgta gtaacaggca
      301 aagaaaactg gaatgattta tatcatgcaa acgaagtatt gaaaatagct gaggagaaat
      361 aaatggaaat tttatttact atttgtggta gagctgggtc taaggggttt aaaaataaaa
      421 atttgaaata tttggcagga aagcccctag tccatttcgc tttagcaatg atagatatct
      481 atcaacaaaa acatcctgaa cataattgca cgacttgttt gaatacggac agtaatgagt
      541 tagtagaatt gacgactaag ttaaatccgt ctgtgaaaat tgtagaacgt aaacctgaat
      601 tagctacaga tactgtaggg aaaattgaag tgatacgtga ttcattctta caactagaaa
      661 gagaagataa ta
//
LOCUS       DAZKCH010000249          670 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.263, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000249 DAZKCH010000000
VERSION     DAZKCH010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.263"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            154..417
                     /locus_tag="ACG84X_002989"
     CDS             154..417
                     /locus_tag="ACG84X_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFP9128759.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..>670
                     /locus_tag="ACG84X_002990"
     CDS             417..>670
                     /locus_tag="ACG84X_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFP9128760.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSART"
BASE COUNT          253 a           88 c          140 g          189 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac
//
LOCUS       DAZKCH010000250          656 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.264, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000250 DAZKCH010000000
VERSION     DAZKCH010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.264"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="ACG84X_002991"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="ACG84X_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFP9128761.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          198 a          143 c          111 g          204 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
      601 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaa
//
LOCUS       DAZKCH010000251          654 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.265, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000251 DAZKCH010000000
VERSION     DAZKCH010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.265"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(89..>654)
                     /locus_tag="ACG84X_002992"
     CDS             complement(89..>654)
                     /locus_tag="ACG84X_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFP9128762.1"
                     /translation="LGLLFAPSIISIFSLTITGFIAFTLVFGKKDTKKMFSKPVAPVK
                     NIAKYFFINVVISAAVSVFLQQILKWGLTGNPINEAFSPLLFIILPIMILGEELFSVY
                     FLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNGNILHTVAHILLIQGVARLLFNQAAI
                     KSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT          243 a          104 c          111 g          196 t
ORIGIN      
        1 tttaatccat tgatacatct gtctttttgt ttaaaggaaa taaagtatgc tttcttagca
       61 atagagcatg tattatttct ataaaaattt aggagaataa aacgactagc aatatagctg
      121 tgaaatcaaa tatcacatga actgcccaac ttgtaatgat cgagttgctt ttaatggcag
      181 cttggttgaa taacaatctt gccacccctt gtatcaaaag gatgtgtgct acagtgtgta
      241 aaatatttcc attatcataa gtactgtaat ggataaatcc aaagatgatt gctgacaaga
      301 aactagcgac aggaatgctg aacttactag aaaaaatagc gagaaaatac actgagaaca
      361 attcttctcc aagtatcatg ataggcaaaa taataaataa taacgggctg aaagcctcat
      421 ttattggatt gcctgttaaa ccccatttca aaatttgttg caaaaatacc gagactgcgg
      481 cactgattac tacattgata aaaaaatatt tggctatatt tttgacagga gcgacaggtt
      541 tcgagaacat ttttttcgta tcttttttac caaaaacaag tgtaaatgct ataaatccag
      601 tgatagttaa agaaaaaatg ctaataatgg atggcgcaaa tagcaaccct aaca
//
LOCUS       DAZKCH010000252          604 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.266, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000252 DAZKCH010000000
VERSION     DAZKCH010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.266"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>604
                     /locus_tag="ACG84X_002993"
     CDS             <1..>604
                     /locus_tag="ACG84X_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFP9128763.1"
                     /translation="TALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVI
                     IGRKERPVSCGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPD
                     NYPDFNSEFGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWF
                     SRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTP"
BASE COUNT          205 a          111 c          113 g          175 t
ORIGIN      
        1 agactgctct tgattattgg caccagtata aagaaaataa gaaaaaatgt ggtagaaaag
       61 tcattcaatt acctgctcat gaagtagatt acattaaaga gaaagtcact cttggttgga
      121 cgcctgacgt cattatcggg cgaaaagaaa ggcctgtttc atgcggtatg agaacacttt
      181 atcgtttatt ttctaaagga atatttgata ttgacacact accgatgaaa ggtaaaagaa
      241 aacccaatgg ccatcaggaa aaacggggaa aacaacagta tcagcgctca atccatgatc
      301 gacctgataa ttatcctgat ttcaattctg agtttggtca ccttgaaggt gatacgatcg
      361 ttggcattca tcataaaagt gccgtcatta ctttagttga aagattatct aaagtcatta
      421 tcacgattaa acccaacggc cgtaaggcat tagatattga aactgccctt aatcaatggt
      481 tttctcgctt ccctaaaaac ttctttaaat ctattacgtt tgactgtgga aaagaatttt
      541 ctaactggaa agccattagt aaccaacatg atattgatat atattttgcg gaccctggaa
      601 cacc
//
LOCUS       DAZKCH010000253          601 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.267, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000253 DAZKCH010000000
VERSION     DAZKCH010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.267"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..467
                     /gene="pssE"
                     /locus_tag="ACG84X_002994"
     CDS             <1..467
                     /gene="pssE"
                     /locus_tag="ACG84X_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PssE/Cps14G family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HFP9128764.1"
                     /translation="LGSQKFQFDRLLKAIDDLIEKGVIIESTFAQSGYSDYKPLNYSY
                     KAFLNRDEFTETMQKAEMVITHGGTGAIIGAVKKGKRVIAVPRLAKYGEHVDDHQLQL
                     IRQFDEMNIIYPCYELENLEDAVKETRVRMFNKYVSNTETIINSIEVLIEKI"
BASE COUNT          233 a           66 c          122 g          180 t
ORIGIN      
        1 cattaggttc acaaaaattt caatttgata gattgttaaa agctattgat gatttaattg
       61 aaaaaggagt aataatcgaa agtacatttg cacagagtgg ttatagtgat tataaaccac
      121 taaattattc ctataaagca tttctaaata gggatgagtt tactgaaact atgcaaaaag
      181 cagaaatggt gattactcat ggaggtacag gtgctataat tggggccgta aaaaaaggta
      241 aaagggtcat tgctgttcct cgattggcta agtatggtga gcatgtcgat gatcaccaac
      301 tgcagttaat tagacaattt gatgagatga atattatcta tccttgttat gaattagaaa
      361 atttagaaga tgccgttaaa gaaacaagag ttcggatgtt taacaagtat gtatctaaca
      421 cggaaacgat tattaattcg atagaggtat taatagaaaa aatataaata taaggagtaa
      481 agcgttatgc aaagagtact tatgattggt aatgacagct cggtaaaagg tggaattaca
      541 agtataatta cacaaatgct caattttaat tgggaaaaaa agaatatcga gatgactttt
      601 a
//
LOCUS       DAZKCH010000254          588 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.268, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000254 DAZKCH010000000
VERSION     DAZKCH010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.268"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(65..150)
                     /locus_tag="ACG84X_002995"
     tRNA            complement(65..150)
                     /locus_tag="ACG84X_002995"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Leu,seq:taa)
     gene            complement(167..238)
                     /locus_tag="ACG84X_002996"
     tRNA            complement(167..238)
                     /locus_tag="ACG84X_002996"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Gly,seq:gcc)
     gene            complement(250..322)
                     /locus_tag="ACG84X_002997"
     tRNA            complement(250..322)
                     /locus_tag="ACG84X_002997"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Thr,seq:tgt)
     gene            complement(340..421)
                     /locus_tag="ACG84X_002998"
     tRNA            complement(340..421)
                     /locus_tag="ACG84X_002998"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(385..387),aa:Leu,seq:tag)
     gene            complement(429..501)
                     /locus_tag="ACG84X_002999"
     tRNA            complement(429..501)
                     /locus_tag="ACG84X_002999"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(466..468),aa:Lys,seq:ttt)
     gene            complement(505..577)
                     /locus_tag="ACG84X_003000"
     tRNA            complement(505..577)
                     /locus_tag="ACG84X_003000"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(542..544),aa:Val,seq:tac)
BASE COUNT          149 a          169 c          138 g          132 t
ORIGIN      
        1 cccctaacct tttgatccgt agtcaaacac tctatccagt tgagctatgg gcgcatattt
       61 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
      121 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      181 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      241 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      301 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      361 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      421 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      481 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      541 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAZKCH010000255          583 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.269, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000255 DAZKCH010000000
VERSION     DAZKCH010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.269"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(38..>583)
                     /locus_tag="ACG84X_003001"
     CDS             complement(38..>583)
                     /locus_tag="ACG84X_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9128765.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSPVQFRKTTVTVV"
BASE COUNT          167 a          110 c          100 g          206 t
ORIGIN      
        1 aaatccactc cttttttcat gctctaaaat gatattttta cacaactgtt acggttgttt
       61 tacgaaattg gacgggactt tgccagttta atttctgttt tatccgttca ttattgtagt
      121 aatagatata gctatcgatg gctgatttta attcctcgaa acagttataa actttcccgt
      181 gaaaaatctc ttgttttaat aagccaaaaa aattctccat aagtgaatta tctaagcagt
      241 tccctttccg agacatgctt tgaaagattt tgtactcctt caatttgttt ctataagctt
      301 tcatttgata cgcccaacct tgatctgagt gaaacgtacg acgataggga caatcgttag
      361 tggtctggat agcttcctcc aaaccttcca ttaccgctaa tgcattgggc ttttcagaga
      421 tacgatagga taaaatctca ctattgaaca tatccataaa aggatctaga tacaatttct
      481 tttgacggat aatgcctttg gcatccactt catggtattt aaattcagtt gtatccgtcg
      541 tgattttctg atggcagata ctggtgtaga aacgacgatg gat
//
LOCUS       DAZKCH010000256          552 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.270, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000256 DAZKCH010000000
VERSION     DAZKCH010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.270"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(23..>552)
                     /locus_tag="ACG84X_003002"
     CDS             complement(23..>552)
                     /locus_tag="ACG84X_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9128766.1"
                     /translation="WHPWEDYRNFFVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVM
                     TQKLSNLDIDYSDSFTLIIEHETGIVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPD
                     SLFSWNEETSSMTDIQLYDEVMHDNNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFE
                     KDKYIINLINDIEVN"
BASE COUNT          192 a          101 c           60 g          199 t
ORIGIN      
        1 ccaaaaaaaa ttactttcat cattaattta cctcaatgtc gttaattaag ttaataatat
       61 acttatcttt ttcaaaagta tattggggtt ccattttctt ttccaaaagc gtgaaaaatt
      121 ctttaatctc ctctaaatat gcatcttcaa taatagtatg tgaataatta ttatcatgca
      181 taacctcatc gtacaattga atatctgtca tactagaagt ttcttcattc catgaaaata
      241 gagaatccgg gttaccttcc cattctatta aaatcttttc accaattata gttaaatttc
      301 ttttagctac tcttgaaaca acatctacac ttaaagttcc aactatacca gtttcatgct
      361 caataataag agtgaaactg tccgaataat caatatcaag attggataat ttctgggtca
      421 ttacagtaaa cgatttaact ttcccaaatg tatctataat ccaaggtaat tcaatagcga
      481 atatttctct acacccatta gtttttttgt ttgaaacaaa aaaattgcga taatcttccc
      541 aaggatgcca gt
//
LOCUS       DAZKCH010000257          530 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.271, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000257 DAZKCH010000000
VERSION     DAZKCH010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.271"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(48..350)
                     /locus_tag="ACG84X_003003"
     CDS             complement(48..350)
                     /locus_tag="ACG84X_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFP9128767.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
BASE COUNT          182 a           92 c           74 g          182 t
ORIGIN      
        1 tatggtgata aaatccgttc cgggctacct tttttaggta gcctacttta atctttatac
       61 ctttctggat caacgaaagt atacttcaaa tagtcataac gccgatgatc gctccgtgcg
      121 tctggcacat cagtcacgat atcaaacaaa aaatacacat ctttcttcat tctggttttt
      181 gttgccggaa ttttaaagta gttcttatta gagtaataga gattgattaa taagctatct
      241 tcgattgcta aaaagaaaac ttctgaatcc cacaccttat aaaaatcttt gacaaatcta
      301 ttcgaaggat caaatttaaa ccataattgt gtttttcctt ccatcaacat aatgttcacc
      361 tcaaaaagag tatacgaact aatgttcttt ttgtaaagta ggaatatcat tgataatatg
      421 gatggaacat atatattaaa aagtgttctt tttgaatgct attttgaatg ccattttcat
      481 tcatttaacg aaaatctgcg aaaataaaaa atgctcaaac ccttataaaa
//
LOCUS       DAZKCH010000258          526 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.272, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000258 DAZKCH010000000
VERSION     DAZKCH010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.272"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..354
                     /locus_tag="ACG84X_003004"
     CDS             <1..354
                     /locus_tag="ACG84X_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFP9128768.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
BASE COUNT          209 a           75 c          115 g          127 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacaga
//
LOCUS       DAZKCH010000259          514 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.273, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000259 DAZKCH010000000
VERSION     DAZKCH010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.273"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..132)
                     /locus_tag="ACG84X_003005"
     CDS             complement(<1..132)
                     /locus_tag="ACG84X_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFP9128769.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DAZKCH010000260          512 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.274, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000260 DAZKCH010000000
VERSION     DAZKCH010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.274"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..343
                     /locus_tag="ACG84X_003006"
     CDS             <1..343
                     /locus_tag="ACG84X_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128770.1"
                     /translation="DNIRDKKASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDL
                     IRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRA
                     SLYRKLSEVNN"
BASE COUNT          206 a           69 c           93 g          144 t
ORIGIN      
        1 cgataacata cgagataaaa aggcaagttt aaaatcacta aaagatacat ggcttgattt
       61 atcagaagat aatccataca gccaattctt aattactgta atggctggtg ttaaccaatt
      121 agagcgagat cttattcgga tgagacaacg tgaagggatt gaattggcta agaaagaagg
      181 aaagtttaaa ggtcgattaa agaagtatca taaaaatcac gcaggaatga attatgcggt
      241 aaagctatat aaagaaggaa atatgactgt aaatcaaatt tgtgaaatta ctaatgtatc
      301 tagggcttca ttatacagga aattatcaga agtgaataat tagccattct gtattccgct
      361 aatgggcaat atttttaaag aagaaaagga aactataaaa tattaacagc ctcctagcga
      421 tgccgaaaag ccctttgata aaaaaagaat catcatctta agaaattctt agtcatttat
      481 tatgtaaatg cttataaatt cggccctata at
//
LOCUS       DAZKCH010000261          508 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.275, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000261 DAZKCH010000000
VERSION     DAZKCH010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.275"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..508
                     /locus_tag="ACG84X_003007"
     CDS             <1..508
                     /locus_tag="ACG84X_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HFP9128771.1"
                     /translation="DLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFS
                     RIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLK
                     VEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELG
                     CANASEAV"
BASE COUNT          155 a           89 c          110 g          154 t
ORIGIN      
        1 agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca ttttggatct
       61 gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg ttctagtaaa
      121 aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc atactgatcg
      181 tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg acatcaatcg
      241 atcattgagt cataaaggct gtccttttga taatgccgta gctgaatcaa cttataagtc
      301 gttgaaagta gaatttgtct atcaatacac atttgaaacc ttacaacaat tggatttgga
      361 gttatttgac tatgtcaatt ggtggaacca ccttcggttg cacggtacac ttggctacga
      421 gacaccggtt ggttaccgta accagagatt ggcgcagcga atccttgata atgagctcgg
      481 atgtgctaac gctagcgagg cagtctaa
//
LOCUS       DAZKCH010000262          494 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.277, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000262 DAZKCH010000000
VERSION     DAZKCH010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.277"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..154
                     /locus_tag="ACG84X_003008"
     CDS             <1..154
                     /locus_tag="ACG84X_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HFP9128772.1"
                     /translation="TYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            167..>494
                     /locus_tag="ACG84X_003009"
     CDS             167..>494
                     /locus_tag="ACG84X_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HFP9128773.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQD"
BASE COUNT          179 a           72 c          101 g          142 t
ORIGIN      
        1 aacttatgga catactggcg ttatccgagg cttagctaat ggtcgtatgc aaacttatga
       61 acaaaacaca gagttaggta tgatttgtgg aaagttagat cgccagtatt atagtgcaag
      121 tgcaatttct tccattgtca taccaccaaa atagggaggt gatttaatgg caaagtggaa
      181 tgtcatatta agtacaacag aaccctataa ttacgtgggg atgattcaag ttcgacaagg
      241 caataaaaac actgaagtta tggaagctac aattgtcgaa aatggtcttc catatgattt
      301 atcagaatgt aaggtatatt ttgaatcagt tgttggcgga aaatatccag tccaattaga
      361 aacaagaatt gtggatgcta aaaaagggaa aatcaaatat atttttgata aatattccat
      421 gcagtgtttg catcgacaaa cagccaattt cattatattt aaaggagaag acttgattgg
      481 aacaactcaa gact
//
LOCUS       DAZKCH010000263          494 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.278, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000263 DAZKCH010000000
VERSION     DAZKCH010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.278"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            42..164
                     /locus_tag="ACG84X_003010"
     CDS             42..164
                     /locus_tag="ACG84X_003010"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128774.1"
                     /translation="MHKPFPDPIQKAIDELGIKNKKRFILVIHYMTCKVRKLVG"
     gene            137..268
                     /locus_tag="ACG84X_003011"
     CDS             137..268
                     /locus_tag="ACG84X_003011"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128775.1"
                     /translation="MQSAKACGIAFGLAKWGAKNIENFQSVDIIIDSPQEILDLLEK"
BASE COUNT          184 a           73 c           87 g          150 t
ORIGIN      
        1 atctatattt tgatatacaa attacagctt cagatactaa gttgcataaa ccttttccgg
       61 accccataca aaaggcaatt gatgaattgg gcataaaaaa taagaaacga tttatattgg
      121 tgattcatta tatgacatgc aaagtgcgaa agcttgtggg atagcatttg gtttagctaa
      181 atggggagcc aaaaatatag aaaattttca aagtgtagat ataattattg attctcctca
      241 agaaatactt gatttgttag aaaaatagac aaagagcgtg agataaggat agggtctcac
      301 gctctttgtt tttcgccatt taaagattga aatttttgcc atcgccgatt gtaaaattaa
      361 gctagacaac taaaaaagtc atttgtgcta cactcaaaat agttccgacc aaagaattat
      421 aaggagtgag tacaaatgac ctatacccat cttacaacgg atgaacttgt aataatagag
      481 tcttatttca aaat
//
LOCUS       DAZKCH010000264          469 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.279, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000264 DAZKCH010000000
VERSION     DAZKCH010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.279"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          177 a           64 c           53 g          175 t
ORIGIN      
        1 ggtctattta actcatcaga cattctatgc tcatttttct ccaaatttgt ttcaactctt
       61 tcgtacttaa ttttgcgtat ttgaaaattc ttcttttaga gtacttttat tacgatacta
      121 gtatgatata tatctatagc aaacagttaa aatcttccta aaataagcga atagcattcc
      181 taaaacctat aaaattttta gatgaagcga caagtggaca attaataaac tacttgaaca
      241 tgaaattatg gatcaccttt caaatttaga aaatggaatt cttatactta ttgcgcaaca
      301 tttattgatt gcaaaattat gtgacaaaaa aaactagtag aagaaagaat aatggcttga
      361 taataaagta ctacctatta aaggtagtac tttatttaat ttagtataaa ttaacatact
      421 actatatttt aggtttcata ttatataaat taataatata ctaccattt
//
LOCUS       DAZKCH010000265          468 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.280, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000265 DAZKCH010000000
VERSION     DAZKCH010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.280"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>468
                     /locus_tag="ACG84X_003012"
     CDS             <1..>468
                     /locus_tag="ACG84X_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HFP9128776.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DAZKCH010000266          465 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.282, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000266 DAZKCH010000000
VERSION     DAZKCH010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.282"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>465
                     /locus_tag="ACG84X_003013"
     CDS             <1..>465
                     /locus_tag="ACG84X_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFP9128777.1"
                     /translation="EGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEAT
                     QPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTK
                     YTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          190 a           68 c          109 g           98 t
ORIGIN      
        1 agaaggaaca agtattgaaa gtggaacaac agtctttgca gtgaaagacg gcgtaagctt
       61 accagaagat aaacttccag tgttgaaagc aaaagatggt tatacagatg cgaaatggcc
      121 agaggaagca actcaaccaa ttacagcaga tgatacagaa tttgtatcaa gtgcaacaaa
      181 actggatgat aaatctgacg ctgacaaata taatcctgaa ggtcaaaaag tgactacaga
      241 attgaataag gaaccagacg catttgaggg aattaagaac aaagaagatt taccaaaaga
      301 tactaagtat acttggaaag aaaaagtaga tgttagcgca gctggaaata aaaaagggac
      361 tgttgtagtg acatatccag atggatcatc tgatgaagtt gaagtagatg ttacagtgac
      421 agacaatcgt tctgacgccg ataaatatga gccaacagta gaagg
//
LOCUS       DAZKCH010000267          449 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.284, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000267 DAZKCH010000000
VERSION     DAZKCH010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.284"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(34..270)
                     /locus_tag="ACG84X_003014"
                     /pseudo
     CDS             complement(34..270)
                     /locus_tag="ACG84X_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          146 a           76 c           77 g          150 t
ORIGIN      
        1 agaaggactg accttctgtc tcagattttt ttgttatttc acttgaatca attgattgat
       61 caaaaaaatc ctgattttca tgttctcaaa tgatttaaat ccataagata atcgtttcag
      121 tgtcttgata tggggaatct tggcctctat tttgccatta gaatacgggt aaatcatagc
      181 attgtaaata ccttcttcat acgttaaaag gttttgaagt ttcgtgcgaa gttgtgcatc
      241 aagtgtttca ggaagatttt ttaataacgc cgtttgtata attaagcgag acaaataaaa
      301 aagccattta tgttacactc caattgtaat acccgctaaa gcatacaagg agagtgaaca
      361 taaatgactt atacccatct tacaccaaac gagcttgtaa tgatagaagc atattttcat
      421 caagaaactc cggttgctat cgttgcgaa
//
LOCUS       DAZKCH010000268          445 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.285, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000268 DAZKCH010000000
VERSION     DAZKCH010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.285"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            145..402
                     /locus_tag="ACG84X_003015"
     CDS             145..402
                     /locus_tag="ACG84X_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128778.1"
                     /translation="MSKLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
BASE COUNT          197 a           58 c           62 g          128 t
ORIGIN      
        1 atttttctgt ccacgttcat attactccaa agttttcctc attccaaaag aaaagcacag
       61 aatacacaaa gaagcgtttt tatttgtata aactatatca aagttctata cttaaattat
      121 caaataaaaa ggacgtgaag ataaatgtca aaattagaaa acaaagaaga aaaagttgta
      181 aacaaaattg tttctgttgt caataaactg gataaagagt tagacgaact tgatacgtta
      241 tctgaaaatc cagaaaaaaa acataaccta aaaaaatggt tagttgaacg aaaggctatt
      301 catgaaatta aaaaagttct tcatgaagct gataaatatg aaaaatatga tgaaaaagaa
      361 cttgacaaag aatttaaaga aatcaatgac ttattactat aattgattta tacgactcat
      421 ttttgagtcg tcagactgca aacaa
//
LOCUS       DAZKCH010000269          437 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.286, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000269 DAZKCH010000000
VERSION     DAZKCH010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.286"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..437
                     /locus_tag="ACG84X_003016"
                     /pseudo
     CDS             1..437
                     /locus_tag="ACG84X_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612146.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          179 a           77 c           80 g          101 t
ORIGIN      
        1 atcttacgcc tgaacaaaaa gaattgttag aactacgtaa aagaaaccag caattagaaa
       61 tggaaaatga tattttaaag caagcagcgc tgatattcgg acgaagagac aagtaatcga
      121 tgcgaataag catctttacc ctatatcagc gatgtgcaga atattaggtc tatcacgtca
      181 gtcctattat tatcaatcaa aaccaaagaa agacgaatca gaacttgaag aagtagtcgc
      241 tgaagaattt atccgcagcc gaaaggccta cggctcaaga aaaataaaaa aagccttatc
      301 aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa atagaggatt
      361 aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca atgaagccaa
      421 aacgacaaac gtattga
//
LOCUS       DAZKCH010000270          421 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.288, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000270 DAZKCH010000000
VERSION     DAZKCH010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.288"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(170..355)
                     /locus_tag="ACG84X_003017"
                     /pseudo
     CDS             complement(170..355)
                     /locus_tag="ACG84X_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
BASE COUNT          120 a           85 c           62 g          154 t
ORIGIN      
        1 tgcaacagaa ccggtaaatg aatgaaaaag atggaagaat cattattcaa tagctttctt
       61 aaatactccg ttataaaatg tgaacaagta aaaagacatc tatccctatt ttctacactt
      121 ccactttact actatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
      181 cattttcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
      241 gtgggtattt aaatggtttc gcttctggat gtttggcttt atatccttcg taatccttac
      301 tgttgataat tgctttcata ttaggaattg gatcttcacc tggcatatat tgcagaggtt
      361 ctgttgcgaa gtttgaaaat caaacgcgcc ctctctgaac tccaaatatc ttaggctgtt
      421 a
//
LOCUS       DAZKCH010000271          411 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.289, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000271 DAZKCH010000000
VERSION     DAZKCH010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.289"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>411
                     /locus_tag="ACG84X_003018"
     rRNA            <1..>411
                     /locus_tag="ACG84X_003018"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          108 a           91 c          131 g           81 t
ORIGIN      
        1 gaaagccccc ggctcaaccg gggagggtca ttggaaactg ggagacttga gtgcagaaga
       61 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccagtgg
      121 cgaaggcggc tctctggtct gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      181 gattagatac cctggtagtc cacgccgtaa acgatgagtg ctaagtgttg gagggtttcc
      241 gcccttcagt gctgcagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      301 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      361 agcaacgcga agaaccttac caggtcttga catcctttga ccactctaga g
//
LOCUS       DAZKCH010000272          378 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.290, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000272 DAZKCH010000000
VERSION     DAZKCH010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.290"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          140 a           61 c           63 g          114 t
ORIGIN      
        1 agaaaacctc cagacttctt gatagctcaa gtatatcttg aggtgcattt gttagtaagg
       61 tactgttcta tggggcgctt actctaggag tgagcatttt tcgaaaaata ctaaaaattt
      121 ttcaaaataa aaaaaggcat acagacaata aactgtctat acgcctcaca gactctattc
      181 tatacatcta attttggctg tcctgcaaaa aatatgtgtt agcctccatc gaaagatcaa
      241 actttggaaa acatcattat aactttgctt ggtaagagct ttgctaaaac atgatatgac
      301 ttgtatacaa aatgtggagt gtattccaat aaataggaag gattacaaaa tttgaaacca
      361 aataagtaaa aaatactg
//
LOCUS       DAZKCH010000273          377 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.291, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000273 DAZKCH010000000
VERSION     DAZKCH010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.291"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>377
                     /locus_tag="ACG84X_003019"
     CDS             <1..>377
                     /locus_tag="ACG84X_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9128779.1"
                     /translation="FLDYEKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGE
                     FKQQTLPAYKRTNDTLETTIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLT
                     EEVNAFKSRALNDKYVAIFMDAT"
BASE COUNT          137 a           66 c           62 g          112 t
ORIGIN      
        1 tttttagatt acgaaaaata tgatcgcact ggttttaatt caggtaattc gagaaacggt
       61 tcttactttc gatcaatcaa aaccgaatat ggtgaattaa cattggaaat acctagagat
      121 cgtaatggtg agtttaaaca acaaacttta ccagcctaca aaagaacaaa cgatacattg
      181 gaaaccacta ttatccattt attcgaaaaa ggtgttacga tgtctgaaat tgctgatttg
      241 atcgaaaaaa tgtacggtca tcactatact ccacaaacca tgtccaacat gactaaagtt
      301 ctgactgaag aagtaaatgc ctttaaatcc agagccttaa atgataagta tgtcgctatt
      361 tttatggacg ctactta
//
LOCUS       DAZKCH010000274          368 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.292, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000274 DAZKCH010000000
VERSION     DAZKCH010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.292"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..272)
                     /locus_tag="ACG84X_003020"
     CDS             complement(<1..272)
                     /locus_tag="ACG84X_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128780.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKT"
BASE COUNT          106 a           69 c           52 g          141 t
ORIGIN      
        1 aaagttttga tttgttgcgt gtgttccacc aatttttctg tatgtgtatc taatctttca
       61 tcgtgtttct ttagttcttc atgaatcatc aatcgatctg atttgctcga ttctaaatct
      121 ttagtcagca aatctaaatt gtggcttact tttgaaagag tctcagtaat tttcgagaaa
      181 gatgcagcaa tcggtctaat tactaataaa atcaaagaaa cgatagcggt tattgatcct
      241 gctatcattc cccattcccc taaattaatc atgtgacaac tcctttacct taaataaaaa
      301 cgcatcaatt aagatgcgct cttatcttta ttaatgattt tatctgcttc ttcgtctgta
      361 atgcataa
//
LOCUS       DAZKCH010000275          362 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.293, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000275 DAZKCH010000000
VERSION     DAZKCH010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.293"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>362)
                     /locus_tag="ACG84X_003021"
     rRNA            complement(<1..>362)
                     /locus_tag="ACG84X_003021"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           72 a          113 c           83 g           94 t
ORIGIN      
        1 aaatccggac aacgcttgcc acctacgtat taccgcggct gctggcacgt agttagccgt
       61 ggctttctgg ttagataccg tcaagggatg aacagttact ctcatccttg ttcttctcta
      121 acaacagagt tttacgatcc gaaaaccttc ttcactcacg cggcgttgct cggtcagact
      181 ttcgtccatt gccgaagatt ccctactgct gcctcccgta ggagtttggg ccgtgtctca
      241 gtcccaatgt ggccgatcac cctctcaggt cggctatgca tcgtggcctt ggtgagccgt
      301 tacctcacca actagctaat gcaccgcggg tccatccatc agcgacaccc gaaagcgcct
      361 tt
//
LOCUS       DAZKCH010000276          335 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.295, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000276 DAZKCH010000000
VERSION     DAZKCH010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.295"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>335
                     /locus_tag="ACG84X_003022"
     CDS             <1..>335
                     /locus_tag="ACG84X_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFP9128781.1"
                     /translation="YVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGER"
BASE COUNT          125 a           53 c           77 g           80 t
ORIGIN      
        1 ttatgttcgc cgatttagag aaacgacggt gtttgaggat atttttgcct atattttaga
       61 acaagcagtt aaagcaggtt ttgtaacaga ggataatttg tatctggatt ctacccacat
      121 caaagctaac gccaataaac ataagtttac gaaagaaatg acccatgatg aagcgaaagc
      181 ctatcaggat gaattagaag atgagatcaa tcgtcaacga atagaggctg gaaaacgccc
      241 ttttactttg gacttagaaa aggaagtgaa gctgaaagaa agaaaaataa gtaaagctga
      301 tccggaaagc ggctactacg tcaaaggcga acgag
//
LOCUS       DAZKCH010000277          327 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.296, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000277 DAZKCH010000000
VERSION     DAZKCH010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.296"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            151..327
                     /locus_tag="ACG84X_003023"
                     /pseudo
     CDS             151..327
                     /locus_tag="ACG84X_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
BASE COUNT          122 a           41 c           63 g          101 t
ORIGIN      
        1 agaattgggc tatttttaat ggcaaagagg ggaagaagat gtttcaaaac aaaggacaac
       61 gctatgttgt aaaaggagta aaggaatctt actggaatca aaaatcttta ttgagaaaat
      121 tatctttgaa tttaagcaca aagaaatgaa ggtacactag atagcaatga agatatcttt
      181 gtcattaaac gtcgctattt tacacaagta agtgatgatt tgattcatgt cttttccaat
      241 gagtggtttg tttctgagaa aaaattacat gcttctaatc tgcaatatat gccaggtgaa
      301 gatccaattc ctaatatgaa agcaatt
//
LOCUS       DAZKCH010000278          326 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.297, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000278 DAZKCH010000000
VERSION     DAZKCH010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.297"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          125 a           45 c           52 g          104 t
ORIGIN      
        1 tggtatgctt cttagtgaat tcaaatataa aagagtttaa agcgtaatac acttatgggg
       61 aagtggtttg gggtgcgctt taaactcttc tttattatta tctcacagca tgcttaaaag
      121 gtctatggat taagttatgt aaaaaagtgc ctctttaaac gtcctaaaat ccaaacaagg
      181 atagcataat atacactatc gttgatccag aaaacaggta aataaatttt gcaaaagcaa
      241 taagttaaaa acattacaaa aaagacaagg atatcacatc aagaaaaaat gttttgaaaa
      301 tatctttgcc tttttgtatt atatct
//
LOCUS       DAZKCH010000279          325 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.298, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000279 DAZKCH010000000
VERSION     DAZKCH010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.298"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>325
                     /locus_tag="ACG84X_003024"
     CDS             <1..>325
                     /locus_tag="ACG84X_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFP9128782.1"
                     /translation="IVHNQVYFGGGINLWLAKKNGIRQRIAHSHATEDGKSQNIVMNV
                     LRKFLTKLLLQNATDYLAVSQEAGESLFQNHPFEIVHNGIDLELYSKNSEAKVNKRKE
                     LDISM"
BASE COUNT          119 a           44 c           65 g           97 t
ORIGIN      
        1 ctatagttca caatcaggtt tattttggcg ggggaattaa tttatggtta gccaaaaaga
       61 atggaatcag acagagaatt gctcatagcc atgcaactga agatggaaaa tctcaaaata
      121 ttgtaatgaa tgtattgcgt aaatttttaa ccaaattgtt gttacaaaat gcaacagact
      181 accttgccgt tagtcaagaa gctggtgaaa gtctgtttca aaaccacccc tttgagatag
      241 ttcataatgg tattgattta gagctttata gtaaaaattc agaagctaag gttaataaga
      301 gaaaagaatt ggatatctca atgag
//
LOCUS       DAZKCH010000280          321 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.299, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000280 DAZKCH010000000
VERSION     DAZKCH010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.299"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>321
                     /locus_tag="ACG84X_003025"
     CDS             <1..>321
                     /locus_tag="ACG84X_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HFP9128783.1"
                     /translation="TQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTK
                     TEHRTVKYLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFG
                     FSVST"
BASE COUNT          107 a           69 c           63 g           82 t
ORIGIN      
        1 acgcaagcag cctatgcttt cttaaaacga ctccataaac agtttggtga gccgaaagca
       61 attgtgaccg ataaagcacc ttctcttggc tccgccttta gaaagttaca gagtgtgggt
      121 ttatatacta agacagagca ccgaactgtg aagtatctta acaatttaat agaacaagac
      181 catcgaccta ttaaacgacg aaataaattt tatcaaagtc tccgtacagc ctcttccacg
      241 attaagggca tggagaccat tcgaggaata tataaaaaga accgaagaaa tggaacgctc
      301 ttcggctttt cggtgtctac t
//
LOCUS       DAZKCH010000281          321 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.300, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000281 DAZKCH010000000
VERSION     DAZKCH010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.300"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>321
                     /locus_tag="ACG84X_003026"
     CDS             <1..>321
                     /locus_tag="ACG84X_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128784.1"
                     /translation="FNGIPWEIIITQYKKSIGSSVFNTLEEYADNFIEFVKTASFIRS
                     EQTEQEQMIGVFQKIISGLFESIEVDINFLISQGTQIDKDVLVKLLQTKMNTNLSQQS
                     QTFI"
BASE COUNT          123 a           41 c           53 g          104 t
ORIGIN      
        1 atttaatggt attccttggg aaataatcat tactcaatat aagaaaagca ttggtagttc
       61 tgtttttaat actttggaag aatacgcgga taattttata gaatttgtca aaacagcatc
      121 ttttattaga agtgaacaga ccgagcaaga acaaatgatt ggggtttttc aaaaaataat
      181 ttcaggttta tttgagagta tagaagtaga tattaacttt ttaataagcc aaggtacaca
      241 aatagacaaa gatgtcctag tgaagttatt acaaacaaaa atgaatacca atttgtctca
      301 acagtcccag acattcattt t
//
LOCUS       DAZKCH010000282          315 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.301, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000282 DAZKCH010000000
VERSION     DAZKCH010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.301"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>315
                     /locus_tag="ACG84X_003027"
     CDS             <1..>315
                     /locus_tag="ACG84X_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128785.1"
                     /translation="HWNAIEGKPTTVKGDKGDPGQAATITIGTVSSGSTASVTNVGTS
                     SAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDKTKLDGIAAGAQKNPGNAT
                     TTT"
BASE COUNT          109 a           62 c           72 g           72 t
ORIGIN      
        1 tcattggaat gctatagaag gcaaaccaac aacggtgaag ggagataaag gcgatcctgg
       61 ccaagcagca acaattacca taggaaccgt ttctagtggt tcaaccgctt ctgttacgaa
      121 tgtaggaaca tcatctgcag ctagatttaa ttttgtttta ccaaagggag ataaaggtga
      181 tcctggaata aatgccacaa ctacagctgt agctacaact acagcaaatg ggttgatgtc
      241 gtccacagat aaaactaagt tggatggaat tgcagctgga gcacagaaaa atccaggtaa
      301 tgctacaact acgac
//
LOCUS       DAZKCH010000283          301 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.303, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000283 DAZKCH010000000
VERSION     DAZKCH010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.303"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..301
                     /locus_tag="ACG84X_003028"
                     /pseudo
     CDS             1..301
                     /locus_tag="ACG84X_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          119 a           60 c           57 g           65 t
ORIGIN      
        1 attcaaaaga attcaaacaa caaatcgtcg atctctatct cgctggtaag cctcgcgcag
       61 aaattattcg agagtatgag cttacgcctt cttctttcga taaatggatg aagcaagcac
      121 aatcaacggg ctcattcaaa gaaagagaca acttaacacc agaacaagca gaattgatcg
      181 cactaagaaa gaaaaataag caactcgaaa tggagaatga tattttaaag caagcggcgc
      241 tgatattcgg acgaaaagac aagtaattga tgccaacaag cataaatatt ccatatcagc
      301 g
//
LOCUS       DAZKCH010000284          293 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.denovo.304, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000284 DAZKCH010000000
VERSION     DAZKCH010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.denovo.304"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>293
                     /locus_tag="ACG84X_003029"
     CDS             <1..>293
                     /locus_tag="ACG84X_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFP9128786.1"
                     /translation="PEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYN
                     PEKYSSKPLIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNL"
BASE COUNT          112 a           33 c           51 g           97 t
ORIGIN      
        1 cctgaattta aaggaacaag aaaaacagga aatattgtcc cttttgaatt tacagtgagt
       61 attcgaccat ttaaggaaaa ttacaatggt agatttacta ttcgacaaac agaaactttt
      121 gaaatttata acccagagaa gtattcttca aaaccgctta ttaaattgag tggttctgga
      181 gatgcttctt tttatattaa taaggataaa tatgatttga aatcgttgga cagagaatta
      241 tttatagatt ctaaattaga agaggcttat cgaaaattag atggtaattt aga
//
LOCUS       DAZKCH010000285        14135 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.067, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000285 DAZKCH010000000
VERSION     DAZKCH010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.067"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..556
                     /locus_tag="ACG84X_003030"
     CDS             <1..556
                     /locus_tag="ACG84X_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFP9128787.1"
                     /translation="LKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFI
                     KRDVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYF
                     QKKLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWA
                     KRFITNDSTIYEQYEYDLSSVENK"
     gene            complement(706..1647)
                     /locus_tag="ACG84X_003031"
     CDS             complement(706..1647)
                     /locus_tag="ACG84X_003031"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFP9128788.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1773..2894
                     /locus_tag="ACG84X_003032"
     CDS             1773..2894
                     /locus_tag="ACG84X_003032"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFP9128789.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3152..4654
                     /gene="eat(A)"
                     /locus_tag="ACG84X_003033"
     CDS             3152..4654
                     /gene="eat(A)"
                     /locus_tag="ACG84X_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFP9128790.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4721..5248
                     /locus_tag="ACG84X_003034"
     CDS             4721..5248
                     /locus_tag="ACG84X_003034"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFP9128791.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            5459..6520
                     /locus_tag="ACG84X_003035"
     CDS             5459..6520
                     /locus_tag="ACG84X_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFP9128792.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6523..7419
                     /gene="murQ"
                     /locus_tag="ACG84X_003036"
     CDS             6523..7419
                     /gene="murQ"
                     /locus_tag="ACG84X_003036"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFP9128793.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7433..9415
                     /locus_tag="ACG84X_003037"
     CDS             7433..9415
                     /locus_tag="ACG84X_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFP9128794.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9480..9926)
                     /gene="nrdI"
                     /locus_tag="ACG84X_003038"
     CDS             complement(9480..9926)
                     /gene="nrdI"
                     /locus_tag="ACG84X_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFP9128795.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            10137..11561
                     /locus_tag="ACG84X_003039"
     CDS             10137..11561
                     /locus_tag="ACG84X_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFP9128796.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(11742..12515)
                     /locus_tag="ACG84X_003040"
     CDS             complement(11742..12515)
                     /locus_tag="ACG84X_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFP9128797.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12512..13417)
                     /locus_tag="ACG84X_003041"
     CDS             complement(12512..13417)
                     /locus_tag="ACG84X_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9128798.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13571..13891)
                     /locus_tag="ACG84X_003042"
     CDS             complement(13571..13891)
                     /locus_tag="ACG84X_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFP9128799.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         4505 a         2533 c         3003 g         4094 t
ORIGIN      
        1 gctgaaacat aatagttcat tttattcgaa acatatgaat ttttcttcta gcgaaccaaa
       61 gacggatcta ttttttggtg caacgaataa tgggagaaaa gaacgagcag aaagctataa
      121 gcaggaattt ataaaaagag atgttacgac caactatttc attcttccac atcgagggaa
      181 tgaacaacct ggatatctta cttatgaaga gtacctgaaa aaaacagggg aatcgcgcgg
      241 gattctggaa ctgttgcggg agggtcagca aggagtgact ttgcggacat ttgaatccat
      301 gtattttcaa aagaaactag tgacggataa tcaagcgatt gctcattatc atttttatcg
      361 tcctgaaaat atttttttgc ttcgagaacg tgatttagat gaattaccgg aatttctgca
      421 tacaccattt aagccaatcc tatcagagct attggaattt tatgatgcag aaaattgggc
      481 aaaacgattt atcactaacg attccactat ttatgagcaa tacgaatatg acctctcctc
      541 tgttgaaaac aaataaaaaa cctacatttt gaagagatta tgtactgaaa caaacaagca
      601 caattcttat ggcatcatga gagttgtgtt ttctttttga tcttttattg ggcttaaaaa
      661 aagagaacca gctgctgatt cagctgattc tcatcagaga gccttttatt ctgcgccaag
      721 gattccttct tttgcatgga ctaattgggt caaaaaggca caatatggtg tagcaatatc
      781 atatttttgt ccttttcgcc aaatggcacc attgatgtag tcgatttcag tcaaacgatg
      841 gtttttgatc aggtcttggt acatagatgg gtaatgcaac ccgatgttgt caggatcata
      901 agtagaagca atatgttggt acacttcttc ttgatctagt atgattcctt cttttgctgc
      961 gatagaagca aattcagata cgattgttcg aaccatgctc tctgccgctt tttgcgcgcc
     1021 tagttcagca atattacaat ccaaaatcgt gcataaacca ttcaatgttc catttacaca
     1081 agcttttcgc caaatggaat aacgaacgtt atggctatag atcggattta aatttgcttc
     1141 ttgaaagact tctacaactt tttttgtaaa tgcttcgcct tctggttcca agttctctag
     1201 ttcgatttct ccatcaccta acaatgtgac ttttccggga ccagctagac cagctgtcca
     1261 catcgtgatc ccaaataaga tatttttctt tggcacatat ttttccagta catcttcatg
     1321 acctaatcca tttagtaaac acaaaacata agtattgtca gtaataatgg attggatcga
     1381 acaaaacata tcatctaatt gattggcttt tgttaatgct acgatcaagt ccacgtgttc
     1441 gttgctttcg atgatttctt ctggtgaata gattggcagt tttgcgacca cttctttacc
     1501 gttaaagtca gcaatcaacc catttgtacg aatggcttca atgtgagcag gccaacgatc
     1561 gatcaagagg acctcatttc cgctttgatg tagcatcaat ccgattcggc tgcccattgc
     1621 tccggcccca gctattgcga ttttcatgtt ttttctctcc tttattcaat gagttccctt
     1681 ttagtatata gaaaaatgga agaaaatagc attgttttgt ttgaaaaaaa tgaaaaaaag
     1741 tgtcttactt aagaagaaag tgagggatac agatggatat tttggcggca attgattcat
     1801 ttaaaggaag tgcttcttca tttgaactaa atcaggcagt tctaaatggc tgggaagatc
     1861 gtaaaggaag aaaaatcaat gtgccgattg cagatggcgg agaaaatact gcagaagcaa
     1921 tctattacgc gctcagggga acatggcgta ccattgatgg gatggatctc ttattccgtc
     1981 agcgaaaaat cagctattta ttgacaactt ggcaaggaaa aaacaccgca gtcatcgaat
     2041 ctgcacaagc attggggtta gatctacttg ataaaccaac ggatcaaact atccgacttg
     2101 cttccagtta tgccttagga gaacttatta aagatgcact gcttcaagaa gtagaacaaa
     2161 ttattgtcac tttaggagga agcgggtgta gcgatggtgg tctaggatta ctccaatcct
     2221 tgggtgcttc tttagaaggg tacacagaag gaaatccttt attatctact aaaaaacttc
     2281 attttgatcg aagaaacgtt cttgtttcta aagtaaaatt gattatcgct gcagatgtta
     2341 ccaatccata tacaggtcaa caaggagctg cttggcaatt tggaagacaa aaaggaggaa
     2401 tagatacgac gctagctttc ttagataaac aagcaggaaa gattgctcag caaataaaag
     2461 atttctggga ggtggattta gatgatattc caggaagtgg agcagcaggc ggtattggtg
     2521 gagccctttt tttgttggga gcgaagatgg tttctggttt cgatttagtc agccaaatca
     2581 ctggattgga aaaaaagatc gaacaagcag atgtcatcat tacaggagaa gggcggatcg
     2641 atcagcaaac gatccacgga aaagttccat acggtgtagc agtgcttgca aaaaaatatc
     2701 gaaaaccaat aatcgctatt tgcggaagta gagaccaaga gctagaagga ctttctgatt
     2761 ttctcccaat tgtcttaagt attcatttgg gtccaatagg tttagaagaa gcaatggaac
     2821 acaggcaaac attagaaaaa acaaaaatct taggacagac acttagcaga tttttcacca
     2881 tcctcccgaa gtagttgaca aaatcatttt ctttatgcta tcgtaatttc aaatatagga
     2941 caaagtgagg gatccgtgca ttgaaaaatt aagtcgattg atgaaagctg cattcagact
     3001 gtaccttgtg gagacaagga agcagtgtgc agattttcgg gattggcttg gttttttcga
     3061 tgtatgggtc tttttgtgtg tatccaaccc ttgcatcctc tttagccagt tctgaaaata
     3121 ggactggtct ttttttacga ggtgatggaa aatgtctaaa atcgaaataa aaaatctgac
     3181 attcggctac gacagccaag gcacattatt atttgaacaa gcaaatctaa attttgacac
     3241 acaatggaaa ctaggactta tcggacgaaa cggtcgagga aagacaactt tactgaatat
     3301 tctacaaaac aaactacctt atcaagggca agtaatccat cagcaagaat ttgcctattt
     3361 cccgcaacag acaaaagata aagaacgttt aacctattac gtgttaaatg atattacgga
     3421 ttttgagata tgggaaatcg aaagagagct ccaattgatg caaacagatc ctgaaatctt
     3481 atggagagaa ttcagcacac tatcgggggg agagaagaca aaagtcctac tggcactttt
     3541 atttgtggat gacactcatt tcccgttaat cgatgaacca acgaatcatt tggatatctc
     3601 tggtagaaaa caagtagcgg cttatttgaa aaagaaaaaa caaggcttca tcgtggtcag
     3661 ccatgaccgg ggatttatcg atgaagtagt ggaccatgtt ttagcaatcg aaaaaagtca
     3721 actggaactt tatcaaggga atttctctat ctatgaagaa cagaaaaaac ttcgtgatga
     3781 atttgaaatg gctcaaaatg aaaaattgaa aaaagaagtc agtaggctaa agaaaacagc
     3841 agctgaaaaa gccgaatggt ctcgttcccg agaaggagat aaaacaaaga aacaagtcgg
     3901 attcatcgat actgaatcta gacgagtgaa taaaggagca gtgggtgctg atgctgcacg
     3961 gacgatgaaa cgatccaaag caatcgtgaa tcggatggag acccagatca gcgagaaaga
     4021 aaaactatta aaagatatcg aatatatcga ttctttgacg atgaatagcc aagcgtctca
     4081 ccataagcga cttttaagcg tagaagatct tcaattaggg tatgaaaatc tgttattcga
     4141 gccaattcat tttacaatcg agcctcatca gcgggtggcg atttcaggtc ctaacggtgc
     4201 aggaaagtca tccattatcc attatcttct gggggcattc aacggcaagg ttataggaga
     4261 aaaataccag ccaaaacatc tgagcattag ttatgcaagc caaaattatg aagacaatcg
     4321 aggaacgttg gcggaatttg cagagaaaaa ccaagtagac taccaagcat ttttgaacaa
     4381 cctccgaaag cttgggatgg aaagagatgt ttttcataac aagatcgagc agatgagtat
     4441 gggccaacgg aaaaaagtgg aattggctaa atctttatca cagccagctg aactatatac
     4501 atgggatgaa ccattgaatt atttggatgt cttcaatcaa gaacaattag aacaactgat
     4561 cttgaacgtg aaacctgcca tgttactagt ggaacatgat caaaccttcc tggataaagt
     4621 atctactgag attatttctc ttgagagaat ctaacccttg taatctcaag aacaacaagg
     4681 tatggttaag gggaactttg ccaacgaagg agagaatcac atgctttatg taacgagaca
     4741 cggagaaaca acttggaacg cacaaggatt agtttgcgga cgggcagatg tgccgctgac
     4801 tgaaaaagga cagatgcagg cacagaaact agcagaaaag gtagtagatt tgcctgttcc
     4861 aatcacgaaa atcatccatt cccctcttca acgagcaaga gatacagcac aagcagttgc
     4921 tgatcgtctc agcttgccgc tgaccgttga tgaacgattg gtagaaatgg attttgggga
     4981 ttatgatgga ctgccaagca aagatgagaa ctttcaaaaa gcacgtttag cgttcgctgt
     5041 acgattccca aatggggagt cagtcttaga tgtgtatgca cggatcgttc ctttattgaa
     5101 agaatgcatc gaagacgaag aaaatgtcta tctgttagtt tgccataatg ccttgataag
     5161 agtgatcaat gcttattttc atccgatgcc taatgagggg ttctttacat tcatggtaga
     5221 taatacagaa ttggtttctt atgagtaatt atgtttttgt gttatttaaa taaaatattt
     5281 caaggcactg cttttgctta gcagtgcctt ttttaggtta tgacaattct tttgataata
     5341 taaactcaac ctttagaaat gaaatttaat tattttaata aaagtattga aattttgttt
     5401 ctttagatat atactctagt catagaaatg aagacggata cagaaaaaga gggataatat
     5461 gtttggcttt tcaatattta tgaacgattc tttgtcagaa gagaagaaac agtatatccg
     5521 ccaaatggca tccaatggct ttgtcggtat tttcacttcc atgcatatac cagaagatga
     5581 tgtttcggca tatcaaaagc gattgatcga actaggaagc gaagcgaaaa agaataaact
     5641 agaattgatg gtcgatattt caggagaggc attggaacga gcgggttttt cattagaaga
     5701 tctaacgcct ttgaaagcaa ttggtgtaac aggtttaaga atggattatc atatttccaa
     5761 tcagcagatt gccgactggt cacatcaatt gaaaatcagt ttgaatgcta gcacgatcac
     5821 gcctaaagat atcgatgaat tgaaagaagc agaagctgat ttctcacaga ttgaagcttg
     5881 gcataattat tatccacgtc ccgaaacagg gctggacaaa gaatggtatc agaaaaaaaa
     5941 tcaatggctc aaaattcaag gtctccttgt ccaaggtttt gtaccaggag atacagagtt
     6001 gagaggccca ctatatcaag gattgccaac tttggaagaa catcgaggga tccatcctct
     6061 tgcaggcgct ctagatctat tagcaagtaa cacggatatt gtttacatcg gagatgcagg
     6121 tctgtcagaa aacgttcagg agcaatttgc ttctttccaa aaagaacaga cagtcttgct
     6181 ccatacggaa cctgtagatg aagaatttta cgaatatata ttagggaagc atacgaatcg
     6241 gcaagacgat gcaagagatg tcatacgaag cgtagatgca cgttttcgag agattccgcc
     6301 tatcccagca agaaatacag ctacgcgtat gaaagggtct attactttag ataacgaaaa
     6361 gtatttgcgc tatatgggtg agatccaatt aaccaaatat gatttgccag cggatgaaaa
     6421 agtgaatgta gtagctaaag ttatcaaaga agagctacca ttgatcaacc aaatcaaagc
     6481 tggtatgaac tatcaattta taagaaaaga aggaagataa aaatgagcaa aatcaattta
     6541 gagaacctaa caacggaacg cagaaaccaa gaaacttttg gattagatga gatgagtatt
     6601 tctcaagccg ttcaactaat gaacaaagaa gatcagaaag tggccgctgc ggttgaaaaa
     6661 gaactgacaa gtatcgaacc agtgattgct aacacgattg agtcctttaa aaaaggtgga
     6721 cgtctgattt atatgggagc cggaacaagt ggaagactag gtgtgttaga tgctgctgaa
     6781 tgcgtaccga cattcggtgt agaaccggaa atggtcatag gtctaattgc tggtggagaa
     6841 gaagcaatga ctgtagctgt cgaaggggcc gaagattctt atgagctagg gcaagaagat
     6901 ctaatcaagc tgaatttgac aaaaaatgat atagttattg gtatcgcagc tagcggtcgt
     6961 acaccatatg tgatcggtgg attagattac gcaaaatcga tcggtgctgt cacaggaacg
     7021 atttcttgca ataaacaagc cgaaatcagt aaacacgcgg atttcccaat cgaagtcgat
     7081 gcaggtccag aatttttgac aggctctact cgattgaagt caggaacagc acaaaaactt
     7141 atcttgaata tgatttctac tatcagtatg attggtatag gtaaagtatt caataacttg
     7201 atggtcgatg tcaaaccaac aaatgaaaaa ctaatcgaac gctcaaaacg aatcatcatg
     7261 caagcgacag aagctgatta cgaaacagct gaaaagtact ttgaagaagc agatcaaaat
     7321 gttaagctgg ctatcgtcat gattttgaca aatagtgata aagaggaagc tcaagcaaaa
     7381 ttagctgaag caaacggatt tgtaaaaggg accttatgag ggggaaaaga ccatggcaaa
     7441 aaacgaactg actttggaag aactggcaaa acaaatttat aaaggggcag gcggcatggg
     7501 caatgtagaa agcattgtcc actgcatgac tcgtgtgcgt atgaagatca tcaatgatga
     7561 tcttgtaaat gtctctgaat taaaagcgat tccaggagtg cttggtgtag tagaagatga
     7621 acagcttcaa gtcatcatcg gacctgggaa agtgaacaaa gtagcacagc aaatggttga
     7681 tttggcaggc gtgaaattag gagaaaaact ttcttctgta agtacagcta cagcaaattc
     7741 atcagcatct ggaaaagacc gtgtaaacga acgggcacaa gaaatgaaag cggcacaaaa
     7801 atcgaaacaa aaaccatcta aaatcaaatc ggtattaaaa gacatttcta atatctttgt
     7861 gccaatgatt cctgcatttg tcggtactgg gatcgtggca gggattgccg cagttttagc
     7921 aaacttagtc acagccggaa cacttgatgc agcaacatgg caacaatata tcgatgtgat
     7981 gaacatcttg aaaaacggga tgtttagcta cctagttatc tatacaggta tcaatgctgc
     8041 acaagttttt ggtgcaacac caactcttgg tggagttatc ggggccgttg tgatgctgac
     8101 agggatgaat ccggaagcac cactgaaaaa cttatttact ggtgaagctc ttgcagctgg
     8161 acaaggtggg atcctaggtg tcatcttcgc tgtttggcta ttgtcaatcg ttgagaaaaa
     8221 actgcataaa gtagtacctg atgcggtaga tatcatcgtt acaccaactc tttcattgat
     8281 tgccatcggt ctgattgaaa ttttcttcat catgccttta gcaggtttca tttctgatgg
     8341 catggtcggt gggatcaact gggtacttgg cgttggtgga gcatttgccg gcttcgttct
     8401 aggcacatta ttcttgccga tggttatgtt cggactgcat caaattttga ctccaatcca
     8461 tgtgcaaatg attgatgaaa ctggtcgtac gctattgctt ccaattcttg cgatggctgg
     8521 tgcaggacaa gtgggtgcag cattggcatt atggattcgc tgcaaaaaag ataaagaatt
     8581 aacagaaatg atcaaaggag ctttaccagt cgggatccta ggaatcggcg aaccattgat
     8641 ttacggagta acattacctc taggacgccc atttattact gcttgtatcg gtggaggtat
     8701 cggcggggca gtgatcggaa tgatcggaaa tgtcggggct atcgctattg gaccttcagg
     8761 agccgctttg atcccattga tctctgacgg taaatggtta ggctacatcc ttggattatt
     8821 ggcagcttat gctggtggct tcgttgctac attcttcttc ggtattccta aagaccgttt
     8881 agaaaaagaa gaattagcga ctgaaacagc cacagtaaat gaagtgcctg aaaaagtagt
     8941 acctcaaact tcagctgaaa gtgtgactat cctctcatca gttgctgacg gaacagttgt
     9001 ttctttagat aaagcaagtg atccagtttt tgcacaaaag atgatgggtg aaggctactt
     9061 tgtagaacca gaaaacggac atatctattc tccagttact ggggtagtca gctctgtctt
     9121 cccaacgaaa cacgctattg ggatcacaac gccaaatggt ttagaaatct tgcttcatat
     9181 gggaatcaac acagttgact taggcggtac gccatttgat gtgaaagtaa cagaagggca
     9241 gcaagtgaca cctgatacgc ttgtagcaga agctgactta gaagcgatca aagcagcagg
     9301 caaagaaaca tccatgatcg tcttggtaac caatatggat cgtgtaaaaa actttgtctt
     9361 ggaaaaaaca ggtaaagcaa aagcaaaagc acctgtgatg gatgtcaaag cttaatatga
     9421 tagaaacaat agaaacgaaa gaagaaactg aaatctattt ttcagcttct tcttttttat
     9481 tatttattgt tttctgctaa aatctgataa attcgtgtca catcagatgg tgttccccgt
     9541 aattcataat ctgccaagaa aggaaagcca aatgtttgtg catattgttt ggctgttaga
     9601 caatactgat tattgaagtt tttatttccg ctaccgacta caccaagaca aagtttatga
     9661 ttgtcttcat gttccagata ttcacgcatc gtttcggtca agatttctgt atcaccgtta
     9721 tctaaaccat ttccgccgtc taaataagta ggaacgaaag taaaaaatgg ttctgtttct
     9781 ttcgtaaaat cactattttc atggatttct tttaaagtaa cttcaggatt gacaggatct
     9841 tctgcatgca ttttttcagc atattctgct agatgtttgg caaaggcacg cgtatttcct
     9901 gaaatcgata tatataaaat gttcatggat catcctccaa ttctttcctt ttagtatagc
     9961 atctttttta agttttttgg tggtgtaatt tggaaaggga ctaggcgctt tgcttgtata
    10021 atgagaaaaa agccggtaga attatatttc tattaaagtt tttattaatt aagtaaaaat
    10081 aaaaaaggtt tgttatactt tttgataaaa gcggttttat tttggaggat gcttacatgg
    10141 atacagagca acagaaaaaa ggaattggtt taattccact tgctgcctta gtaattggtt
    10201 cagcgattgg aggtggcgta tttggtatta tgacggacat ctccggatcg gctggcggcc
    10261 cagctatttt cagttgggta ctcgtaggaa cagcaatgtt gatgctctcc ttgtcgatca
    10321 ataatatcaa taaaaaacgt ccagatttaa aaggcgggat ctttagttac gcagaagaag
    10381 gttttggccg tttcgctggt tttatcagcg gttggggtta ctggctcaca tgctggttag
    10441 gcaacgtagc ttttgcaaca ttgttgatga gcgcattagg atatttcttc ccagtatttg
    10501 aaggtgggca aaatctggca tcgatcgtga tgagtacagt ctttttatgg ggatatgcat
    10561 ggctagtgaa tcggggagtc gaaaatgcta gtttcgtcaa tgctatcgtc acattctgta
    10621 aattagtgcc attattttta tttattgtag tagctatcag cacgttttcg atccaacaat
    10681 tcattgataa cttttctagc gacattatat tgaatgcgaa tggacagccg atcccgtttt
    10741 ccagtcaagt attgagttgc atcatggtga tgctttgggt atttgttggt attgaaggag
    10801 cctctgtcgt aggttcacga gcaaaaaaac aatcagatgt tgggaaagca acgattctag
    10861 ggatattcgg cttgattatt atttacgtct tggtttccat gcttccatat gggacaatga
    10921 cgatgaatca gctgcaaacg atcaaggcgc agcctgctat gggctatgtg tttgaaatga
    10981 tggttggtaa atggggagca gtcgtgatca acggcggttt gatcatttct ttagttggtg
    11041 tttggctctc atggacgatc ttaccgattg aaacaatggg aaacatggct gaagacggac
    11101 ttttgcctaa agcatgggga aaactcaaca aaaatggggc accaacttat gctatcgtat
    11161 tgacgacgtt atgtacgaat gtctttttac tttcattatt attcactgac agtgcttata
    11221 actttgctta cacacttggt acagcagcta ttttcttcac gtggcttttc ttaggattgt
    11281 accaaatgaa actttcttat cagcggaaag aatgggtcca atttttagta gggcttttag
    11341 caagtgcctt tcaagtatgg gctatgctag tcgtagcctt taatgaagta atgcttgttc
    11401 ttgttctttt cttgccaggc atttattttt acctcaaagc acgtaaggag caaaacgagc
    11461 ctgtacaaca tatccactta gataagattt tacttatagg tgtgacgatg gtcggagtga
    11521 ttgcaatggt tttatttgcc actgggatgc ttcacgtata gaagtataaa agaagtataa
    11581 agagaggttg tgagcctgtc gtttattcaa aaacatacta ggaaaggagc tgtgacacaa
    11641 atgttgtcac agctcctttt tcagaataaa cggtgtttaa gagacagcca atcggcaata
    11701 aggctgaacg tctctttcac agcctctttt ttgatgagtc atcatacatt ttttcgctta
    11761 aatacgagat atcctaatgc taagaacaaa acgatgtaag ctaaattacc gaatagcatt
    11821 tgattagtag aaagatgagt caattgcttc atgatctctt cgtttccaat ttggttttgc
    11881 agattcaaca tactgatcgg attccatttg atccactccc atttttggat gagtgcaata
    11941 aggataccag atatgattga cgaagcaaaa taaaagacga ttcctgctga gatggatgcg
    12001 ccggaactat tgataaagca agcaatcatc aacactaaac ttaaaatcag ccataaaccg
    12061 atataactac ccaaagtata agtgaacaag ctttggatca gtgtttgacc agtagaaacc
    12121 ttctccgtga aggaaatcga agggaaaaga atcagtttca tcaacacagt gacaataata
    12181 gctaaaaggt ataaataaac agaataaata actaatgtga tccatttgct tactaatatt
    12241 tctcctcgag aatactttcg ataaaggaga tttttcaatg taccatattg tgcttccatc
    12301 gaaatgatcg tgcttgcagc tgcaatcatg ataaagacaa tccaagatgt ggcactaaaa
    12361 agctgagcag tcatttcaac tggatcaatg atcgtcgtgt attttttggc tagaagtgct
    12421 gttcctatga gcaaaacaac taatagaaca gataaaacag cagttgactt tttcttgatc
    12481 aatttaaata attcttgttt tacaagcaat gtcatttttc ttcttccccc tttactgaat
    12541 ccagaatttc caatagagaa gattccaaat cattcgtcag atgctggacg tctgtcacat
    12601 ggatattttg tgcagacaat agctggatca cggttcctaa taattcttcg ttttctttta
    12661 aaagcttgat tttatcagga tcttccaaag tatatccagc ttctgtcaag atcgttcgag
    12721 cagctagatc atttgttgta gagataacga tgaaatcttg cgctgtttgg ttcaattcag
    12781 ccattgtaca ttgtttgatg atctttcctt gattgatcag gatcagctca tcgaccattt
    12841 tttcaagctc gctgagtaag tgactggaga tcaagaaaga ggtgccctga gtagccaagt
    12901 cggtaatgat ttttcgcaca tctcttgttg cttgtggatc caaaccgttc atcggctcat
    12961 ctaaaataac gatagacgga tggttcagta aggcaagagc aattcccaat ttttgtttca
    13021 ttcccaacga gtaggatttc gcttttttgt gaatgtactt ttccatcttg agctgattca
    13081 cgatagtgtc gatagcagat acatcgttgg tttcagagaa taacttcaga tgatcatagc
    13141 ctgttaagaa tggatagata cccgggtatt cgatcaatgc tcctacttgt tccaaccctt
    13201 tatgactaga gggagaaatc tcattttcac caatacagat tgttccatct gagtaatgga
    13261 tcagtcctaa aatagctttc atgatcgttg tttttccagc gccattagga cctactaatc
    13321 caacgatttt gccaggggat aagctaaaac tgacatcgct gagggcttgt ttgtgaccaa
    13381 agttcttgga taattcttgg accgaaagac ttttcaaaaa tattcactcc ttttctatag
    13441 atagtacaag catacacctg atgagtggag aagtcgctag gtcattggac ttatttctta
    13501 ttttttcata aaaaaattga atattaaata aaaaggctta ttttttctga tcagtactta
    13561 ttccaagtgt ctagtggccg ctagtaatct tgatgccaat gatactgatg agtagcatcc
    13621 ccacaaagaa ccaagtggaa agattcagct tatcatgaaa caagaccaca ccaattatga
    13681 ccgaaccaac tgcgccaatc cctgtccaga taggataaga gagactcatc ggcaaacttt
    13741 tgattgcctt tgacaaaaag taaaaactag caatcatgcc aatcactgtg taaaaagaat
    13801 aattgatttt agaaaaacca tcactccatt tcatcatcgt tgaccagaat acttccaaaa
    13861 ttcctgctat gattaattcc atccatgcca tacttacatt cctccttaac tataaaaaaa
    13921 tacacaaaaa gaggaaaatc atcccttcaa agacctaatg gaatgatcat cctctttatc
    13981 ctacccggtg gcagattgta tatctttttc tgtagtatag cacacctatc cagatatcgg
    14041 caatctcata ctttttagta aagtgtacca agcactgacg gatatatcgt tagcggaaaa
    14101 gaagatgaat gctttgcaat ttcatagaaa gaagt
//
LOCUS       DAZKCH010000286         8062 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.102, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000286 DAZKCH010000000
VERSION     DAZKCH010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.102"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            128..1564
                     /locus_tag="ACG84X_003043"
     CDS             128..1564
                     /locus_tag="ACG84X_003043"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9128800.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="ACG84X_003044"
     CDS             1753..4200
                     /locus_tag="ACG84X_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFP9128801.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="ACG84X_003045"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="ACG84X_003045"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFP9128802.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            5487..5693
                     /locus_tag="ACG84X_003046"
     CDS             5487..5693
                     /locus_tag="ACG84X_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128803.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(5690..6793)
                     /locus_tag="ACG84X_003047"
     CDS             complement(5690..6793)
                     /locus_tag="ACG84X_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFP9128804.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="ACG84X_003048"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="ACG84X_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFP9128805.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2697 a         1375 c         1751 g         2239 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattacttc ttgaattttt gtgaaattcc
     7981 aacttatttc cgaagaagct acttttggaa caccgtgtac cagaggttgt gaaaaagtcg
     8041 cttagtttcg agtagtaaga aa
//
LOCUS       DAZKCH010000287         6737 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.112, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000287 DAZKCH010000000
VERSION     DAZKCH010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.112"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..90
                     /locus_tag="ACG84X_003049"
     CDS             <1..90
                     /locus_tag="ACG84X_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein"
                     /protein_id="HFP9128806.1"
                     /translation="FLEDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(261..1454)
                     /locus_tag="ACG84X_003050"
     CDS             complement(261..1454)
                     /locus_tag="ACG84X_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9128807.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDRKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVLENDTKKKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQQVMKKRPKAEPFVIDGRGNFLFVNHKGKPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(1533..1739)
                     /locus_tag="ACG84X_003051"
     CDS             complement(1533..1739)
                     /locus_tag="ACG84X_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFP9128808.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            complement(1732..2874)
                     /locus_tag="ACG84X_003052"
     CDS             complement(1732..2874)
                     /locus_tag="ACG84X_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFP9128809.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRYPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CDGVIRRFDLAINDMCGLLDIPVLSEKYRNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRGTKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
     gene            3386..4021
                     /locus_tag="ACG84X_003053"
     CDS             3386..4021
                     /locus_tag="ACG84X_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9128810.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            4175..4252
                     /locus_tag="ACG84X_003054"
                     /pseudo
     CDS             4175..4252
                     /locus_tag="ACG84X_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            4566..4613
                     /locus_tag="ACG84X_003055"
                     /pseudo
     CDS             4566..4613
                     /locus_tag="ACG84X_003055"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4629..6548
                     /gene="tet(M)"
                     /locus_tag="ACG84X_003056"
     CDS             4629..6548
                     /gene="tet(M)"
                     /locus_tag="ACG84X_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFP9128811.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            6667..>6737
                     /locus_tag="ACG84X_003057"
     CDS             6667..>6737
                     /locus_tag="ACG84X_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFP9128812.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPL"
BASE COUNT         2029 a         1214 c         1321 g         2173 t
ORIGIN      
        1 tttttagaag atggaacgcc tcaacaaatc tttgaaaatc cgcaaaatga acggacaaaa
       61 gatttcttga ataaagtatt aaatatttaa aataaattat atatgtcttt ttgactatct
      121 ttttatatct tcttaaatgt ccgcaaagcc ttattttata ggctctacgg gcattttgct
      181 tttgtggtaa acctcacata tctaggtcta tcttcttata ttttcactat caagcgtggt
      241 taaaatcgtg gtaaatactt ctatgcaatt agacgctgaa cctctgattt tgcggtatct
      301 atggacgcat gagcatacca gttcattgtg atactgatat ttgaatgccc catgatatac
      361 tgtaaatctt ttgggttcat gttcttgctt gccagtcttg tgcagaatgt atggcgtagc
      421 gtatgcggtg tgatatgtgg caatggattg tccttgtggt gcttgttgta tttctttacc
      481 atacggataa ataaggcgtt ataatcaatc gcaactttgg gcttgccctt atgattgaca
      541 aataggaagt tgccccgtcc gtctatcaca aatggttctg cctttggacg ttttttcata
      601 acctgttgaa atgcctgtat cgtttctttg cttaatggta cttgccttat tccgcttttt
      661 gttttaggcg tttcaatata atagccctgt tccttgctct ttagtaactg gtggtcgata
      721 atcacaactt cattcttgaa atcaatgtcg gctactgtca gtccgcacag ttccgaaata
      781 cgaagtcctg tctttaacag tatcagcaca tcatcataat gcttgtgata cacattgtcc
      841 gtcttgatga atgagagtaa ggcttgttcc tgttcctctg tcaatgcgac tttctttttg
      901 gtatcatttt ctaggacttc actcaacttg aaatcaaagg gatttttcct cacataatca
      961 tcttgaatgg ctatgtagaa tgacgctttt aacgagcgtt tatggttgtt aatggtattg
     1021 taggaaaagc ctttgtcttt catgcgtaac gcccattcct tagcgtcaga gggtttgatt
     1081 gtatcaatgc tcctagcacc taacttgtcc tctttcaata accgcatgag ttgttcccgt
     1141 tgtttctgtg tgcttttctt cacatttgcc ctctgtgcgt tctgtttggc ataaagttgg
     1201 caaagcgtca ttttcttgcc agtgctgtcg ataccgtcct caatatcccg tcttatctgc
     1261 tgttccagtt ctcgaagtga gggtttttcc cgttttccct ttggtgtcgg gtctgtgggt
     1321 gtcaatctcc aagcatacac atattttgtg tttccaaatg cgtctacata tttatataag
     1381 tattttctgt ctgttcgttg gctctctcca gtatgcagga tacgaccttt gttatcccgt
     1441 cttttttctt tcatggtgtc tgctcctttc cttgttggaa agagccttga tatgacttgt
     1501 gttcatcata acacatacaa ggctcatttg cattagatag cgtccaattt atcaatgacc
     1561 tgttcaaact gtcggcgttt aatctgtatg cggttgccat tcataatgag ccagccagcg
     1621 tccttgtttt cctctgccaa tcgtcttaac ttgttttctc cgatacggaa atactttgac
     1681 gcttcttcaa tggtaagggt gtatttttcc catacgggaa tatcctgtgc attactcata
     1741 aaacaccccc tcactttcga ttacgtctgc tatgtccgta cacatctgtt ccacaagcat
     1801 ttcctgcttt tcagagaggt gggtacattc atcaatcatt ttcatgtagt ttgagcctgt
     1861 cagcctgtcg atttcctcta tcatcacgat tgacggcatg acctgtcttt ccagccattg
     1921 cagagtgcgt tccatattga caggtacggg gttcatttca aaaggtaaac tgtcatggga
     1981 aatgaatatc tcccacagcg gatagtcggg aaattgcaca aaatcagtaa taaggtaaaa
     2041 caccagccca tgagggttat atgtcaataa caattcctca actgcctgta ctgcttttgt
     2101 accacgcaga cgaatttcaa aacgattgat aatatccgta tgtttctttt tggttgcctg
     2161 ttccttttgt ttttcataca ggcagaagta ttttgtgctt gcctttgaac cgatataaag
     2221 ggtgcttgct aaattacggt tttttccgct tagttttcca ccctgcacat tttcataatt
     2281 tttacagcga caatccgcac cgccatttct gtatttttca gacaaaacgg gaatatccaa
     2341 cagaccacac atatcattga ttgccaagtc aaaacgtcgg ataacaccgt cacagtcaag
     2401 acagcggttt aaaaatgaat accaatctct gttctgtgcc tgcaagacat attccatgtt
     2461 gcgtgagcct gcccctttta attccaagaa tacgcccatg tgttcgtcat cagaagccat
     2521 gaccttgatt tctccgtagg cgtaatgctc tttatagcca taatacccat agtcataatg
     2581 gataaaataa tctgctttca tgccaagcac ctttcggata atttccaatg cgtcagtcgt
     2641 tggataacgg acagacagat aatcaacgag cagataaaaa ggcttatcgc agatataata
     2701 attcagacaa cgcaggataa tattttgtgt ttccttgctg gcgttggctt ttccgttctc
     2761 aaagcggttg atactatatc ttgatacatg ggtaagactt gcaagttctc cttgtgaaag
     2821 accgcttgca agacgtttgt tcttcatttc aagtgcaaat tctaaattgt tcattgtatt
     2881 cctccaatcc cacaatagcc ttgaaatacc tgtaaacctc tattcaaaaa gtgtgatatg
     2941 cactatcttc ttaaaacttc tcattactac tcacaacttt gggattgtat ggtttttgac
     3001 ttgtcttttg tgaaatagtg cccccctgtt agataacggg ggcacagaca aggctcgcag
     3061 gctcgccagc cgacaaagca tttcttcccc ttgacacaag gtgtcatggc ggtaagcctg
     3121 agaggcttcc gccaccgtgt cagaaatact ttgtcagcaa gttctgtttt gccttttcta
     3181 acaagttcca tttcaaccga tattcatatc tacggattta atcagatagg tatttctttt
     3241 tgaatgtttt tatatttcat tctattgtgc ttattcgatt acaagaacat agtaattctt
     3301 atatgcttat ttgtcaatat ctttttttgc ctttacaaat catattaagc atgatagact
     3361 tataatagcg aagatataac gagatatgga gggttatgca atgaaaataa gccatttagg
     3421 aaataatata cagaccataa gaaaatttag gggaatgaaa caacaggaac ttgcggacaa
     3481 aatcggtatc aatatgcaga gcctttccaa gattgaaaga gggttgaact atcctgccta
     3541 tgaaacgctg gaaaagataa tggaagtgct ggacgttacg cccaatgaat tgttgtcggg
     3601 agaatggaag tatgtcaatc aatctgaaaa ggaagtctgt cagtttttaa gagccgaaga
     3661 acgtctaaat gcagaactga aacatggaca ctatgataac ttctttgaca gcgaggaaga
     3721 atggctggaa tatgagttag aaaagttacg ggaatatatt acagactata tcaacgggaa
     3781 aagcattgaa gcgtccgacc tttacccaat caaagaattt atccagcatt tgaagtttca
     3841 aaaattatta gaccgctatg atgatttata cagtatggat atgtttgggg aaagcataga
     3901 gggacataag tataagacac cttatcaagt cgtgaaaatg ataaacccga actcaaaaga
     3961 agatatggaa ctgttacgag aagtattaag gaataacaat tttgatgatg aggacgagta
     4021 acttttttcc tcttgcgaga agatacagca aacaaaaagc ccgatcaaga gtgcaaagca
     4081 ccaccaatgg tggcaaagct cttgacaggg ctttttcttt tctgttgtgg gcaatcaaga
     4141 ggaagaaagg gataaaatct gatttgtggt aaatcaggca aaggcaacgc aggtatctca
     4201 atttgatttg gtacttgaaa agaacgggag taattggaag attatagaat aacaaatatt
     4261 ggtacattat tacagctatt ttgtaatcac gtactctctt tgataaaaaa ttggagattc
     4321 ctttacaaat atgctcttac gtgctattat ttaagtatct atttaaaagg agttaataaa
     4381 tatgcggcaa ggtattctta aataaactgt caatttgata gtgggaacaa ataattggat
     4441 gtcctttttt aggagggctt agttttttgt acccagttta agaatacctt tatcatgtga
     4501 ttctaaagta tccggagaat atctgtatgc tttgtatgcc tatggttatg cataaaaatc
     4561 ccagtgataa aagtatttat cactgggatt tttatgccct tttgggtttt tgaatggagg
     4621 aaaatcacat gaaaattatt aatattggag ttttagctca tgttgatgca ggaaaaacta
     4681 ccttaacaga aagcttatta tataacagtg gagcgattac agaattagga agcgtggaca
     4741 aaggtacaac gaggacggat aatacgcttt tagaacgtca gagaggaatt acaattcaga
     4801 caggaataac ctcttttcag tgggaaaata cgaaggtgaa catcatagac acgccaggac
     4861 atatggattt cttagcagaa gtatatcgtt cattatcagt tttagatggg gcaattctac
     4921 tgatttctgc aaaagatggc gtacaagcac aaactcgtat attatttcat gcacttagga
     4981 aaatggggat tcccacaatc ttttttatca ataagattga ccaaaatgga attgatttat
     5041 caacggttta tcaggatatt aaagagaaac tttctgccga aattgtaatc aaacagaagg
     5101 tagaactgta tcctaatatg tgtgtgacga actttaccga atctgaacaa tgggatacgg
     5161 taatagaggg aaacgatgac cttttagaga aatatatgtc cggtaaatca ttagaagcat
     5221 tggaactcga acaagaggaa agcataagat ttcagaattg ttctctgttc cctctttatc
     5281 atggaagtgc aaaaagtaat atagggattg ataaccttat agaagttatt actaataaat
     5341 tttattcatc aacacatcga ggtccgtctg aactttgcgg aaatgttttc aaaattgaat
     5401 atacaaaaaa aagacaacgt cttgcatata tacgccttta tagtggagta ctacatttac
     5461 gagattcggt tagagtatca gaaaaagaaa aaataaaagt tacagaaatg tatacttcaa
     5521 taaatggtga attatgtaag attgatagag cttattctgg agaaattgtt attttgcaaa
     5581 atgagttttt gaagttaaat agtgttcttg gagatacaaa actattgcca cagagaaaaa
     5641 agattgaaaa tccgcaccct ctactacaaa caactgttga accgagtaaa cctgaacaga
     5701 gagaaatgtt gcttgatgcc cttttggaaa tctcagatag tgatccgctt ctacgatatt
     5761 acgtggattc tacgacacat gaaattatac tttctttctt agggaaagta caaatggaag
     5821 tgattagtgc actgttgcaa gaaaagtatc atgtggagat agaactaaaa gagcctacag
     5881 tcatttatat ggagagaccg ttaaaaaatg cagaatatac cattcacatc gaagtgccgc
     5941 caaatccttt ctgggcttcc attggtttat ctgtatcacc gcttccgttg ggaagtggaa
     6001 tgcagtatga gagctcggtt tctcttggat acttaaatca atcgtttcaa aatgcagtta
     6061 tggaggggat acgctatggc tgtgaacaag gattgtatgg ttggaatgtg acggactgta
     6121 aaatctgttt taagtatggc ttatactata gccctgttag taccccagca gattttcgga
     6181 tgcttgctcc tattgtattg gaacaagtct taaaaaaagc tggaacagaa ttgttagagc
     6241 catatcttag ttttaaaatt tatgcgccac aggaatatct ttcacgagca tacaacgatg
     6301 ctcctaaata ttgtgcgaac atcgtagaca ctcaattgaa aaataatgag gtcattctta
     6361 gtggagaaat ccctgctcgg tgtattcaag aatatcgtag tgatttaact ttctttacaa
     6421 atggacgtag tgtttgttta acagagttaa aagggtacca tgttactacc ggtgaacctg
     6481 tttgccagcc ccgtcgtcca aatagtcgga tagataaagt acgatatatg ttcaataaaa
     6541 taacttagtg tattttatgt tgttatataa atatggtttc ttgttaaata agatgaaata
     6601 ttttttaata aagatttgaa ttaaagtgta aaggaggaga tagttattat aaactacaag
     6661 tggatattgt gtcctgtatg tggaaataaa acacgattaa agataaggga agatactgaa
     6721 ttaaaaaaat tccccct
//
LOCUS       DAZKCH010000288         5287 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.124, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000288 DAZKCH010000000
VERSION     DAZKCH010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.124"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1236
                     /locus_tag="ACG84X_003058"
     CDS             <1..1236
                     /locus_tag="ACG84X_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFP9128813.1"
                     /translation="LLGNLAVANTTVLAEESTETVATQTSSSSETGIENDTESTLQSA
                     TVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDGQTLTHTHQADL
                     SEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIAQAIVESGWGNS
                     TLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSYKESLQDNVTVL
                     KTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNVIETYNLTQYDT
                     APTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPNSGQPVYRLYNP
                     YSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKTGTHHYTLSAKE
                     RDWLTPMGWRYEGIGFYGY"
     gene            1723..2187
                     /locus_tag="ACG84X_003059"
     CDS             1723..2187
                     /locus_tag="ACG84X_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9128814.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            2171..2800
                     /locus_tag="ACG84X_003060"
     CDS             2171..2800
                     /locus_tag="ACG84X_003060"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFP9128815.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            3154..4632
                     /gene="msr(C)"
                     /locus_tag="ACG84X_003061"
     CDS             3154..4632
                     /gene="msr(C)"
                     /locus_tag="ACG84X_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFP9128816.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            4679..5125
                     /locus_tag="ACG84X_003062"
     CDS             4679..5125
                     /locus_tag="ACG84X_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFP9128817.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
BASE COUNT         1770 a          916 c         1078 g         1523 t
ORIGIN      
        1 cttttaggaa atctagcagt tgccaacaca acagtgctag ctgaagaatc gacagaaact
       61 gtcgcaactc agacatcgag ttcttcagaa acaggaattg aaaacgatac agaaagtact
      121 ttgcagtcag ctactgtctc agaaaataca atttcaaccg aagaaccaac aactgaaaca
      181 acagaacaaa cacaaaccga agacagtaca tcagcagaag ctcagaacaa tccagagaat
      241 gcagaagaaa tcacgaacca attgacagat gggcaaacat tgacacatac ccatcaagca
      301 gatttgtctg aattcgaaaa ctatactggc tatgcttttt atgctcgctc atctgctaat
      361 tctcaacaag cgttcattga tagtattgcc tcaactgcac aaagtttggc aagtgccaat
      421 gacttatatg catcagtcat gattgctcaa gccatcgttg aaagtggctg ggggaacagt
      481 actttggctt ctgcccctaa ttacaatcta tttgggatta aaggaagcta taatggccaa
      541 tctgttacga tgcctacttc ggaatatgtg aatgggcaat ggattacggt gaatgccgct
      601 tttagaaaat atccttcgta caaagaatca ttgcaagata acgtaacggt attgaagacg
      661 acttcttttc agccaggcgt ttactactat tccggtgcat ggaaaagcaa tacgaactct
      721 tacaaagatg ctacggcttg gctaacaggt cgttatgcca ctgcgcctaa ttatggttct
      781 acattgaaca atgtaatcga aacctataat ctgacacagt atgatacagc accaacttca
      841 acttctccga tgtatcgtct gtataaccgt catacaggag aacatttata tacattgaat
      901 gccggagaaa aaaattatct gccaactgta ggctgggaat atgaagggat tgcttggcaa
      961 gcaccaaaca gcggacaacc tgtctaccgt ttatacaatc cttacagtgg agaccatcat
     1021 tacacaatgg cacaatctga gatcaactct ttaacaaaaa tcggttggcg ttatgaaggt
     1081 ctaagttttt attctggtgg ttccaagcca atttatcgac tatttaatcc aaatgaaaaa
     1141 actggtaccc atcactatac cttgagtgct aaggaaagag attggctaac accgatgggc
     1201 tggagatatg aaggaatagg attttatggt tattaaaaag aggtagtgaa aaagctgccc
     1261 tgcatcaagt agtaagaaca gccaaacaaa aacagatttt catgtttttt gtttggttga
     1321 acttattacc gcagatgcaa gtttttgaac accgtttact caaaaaaggt tgtgacaaca
     1381 tcttgtcata acttttttat tactgtttaa gcatactgat ccaatttcta atattcgacg
     1441 ggattcttgc aaaaggcgat ttcggaaatt tttggcggtg taaaattatc tactgcagaa
     1501 gagctatctt ctatagtttg ataagaatca ataatcttgg ttttagcgtt gtgctttctt
     1561 tatcattttt tccgttcatt ctacaaaaaa tttcttttct ctatactttt ctattgagag
     1621 cgtttttttt attacacagc tgattctttg acttttttct ttttttattc tattattgac
     1681 aagtcaatcg ttgacgagtc aattattaga aaggaggaaa ttatgtcttt agaagagatt
     1741 agtcaccttt tatatcaaat caaattagcc gatcaaaaaa tcgtccagat ctttgaagaa
     1801 aatatcggta taagtcttac tagatacgag atcatgatga gactgaaaga agaaaatcca
     1861 ttgctacaaa gcagtttgca agaaaagttg cagattgatc aaggagcagt tactcgtcat
     1921 ctgaaggtat tggaagcaaa tggctatgtt tcgcgtcaga gaaatcctca gaacaaccgg
     1981 gaagtgtatg tagcgctaac agaaaaagcc cagaagaaaa tcaagcattg tgaaatggac
     2041 cataaagata caggttccgt gctatccccg gctttcagcg atgtagaaat gaaacaattt
     2101 ctaacacttt tagataaatt gaatacccaa ctttgcaata taacaacaga aacgaaagag
     2161 gttaataata atggaacaaa aaaatgattt ttcaacaatt atgactggta gaagatccgt
     2221 tcgcgtatat gatgaaacat acaaaatccc acacgaagaa atgctggaaa tgatcaaaga
     2281 agcgacgact gcaccttctt ctgtcaatat gaaaccatgg cgctttgtgg tcgctgaaag
     2341 cgaggaagca aaagaaatct tgcgtccttt gatccgtttc aatacgagac aaaatgatac
     2401 ttcttctgca atggtcatga tttttggcga tatgcaatgt tacgaatatg gcgaagaaat
     2461 ctacaaccaa gcttacgaat cagggaagat gccaaaagaa gtcagagatc aacaattagc
     2521 tgcgatcatt ccttattaca agagtttttc aagagaagaa atgaacgatg tagtcaaagt
     2581 cgattctagc ttagcggcta tgcaattcat gttagttgcg cgtgatcatg gctatgaaac
     2641 aaatccaatt ggtggattcg aagcagatca gttggcagag gcatttggtt tggataaaga
     2701 ccgttatgtt ccagttatta ttttatcaat aggaaaagcg gtagaagaag gttacgagtc
     2761 tgttcgttta gcaccagaaa agatcactat gttcgaataa aaggttttca gttactattc
     2821 agtagctatt gctttttttg aatcgtgtgt ggtaacctaa taaaaaagga ggtcggaaaa
     2881 atgactgcat cgatgaaatt acgtttcgaa cttttgaata acaactaaat aaattcaaaa
     2941 gacatgtata aacaacaatt tcatggatgg agtatgtcca ttttttcgaa cgacagtaga
     3001 ataggtgaaa gctatgacag atttggtgat ttagtcatag ttatttcgtt cagagtagga
     3061 aaagatgtga tgcagttttt ttgcaaacag atttttctgc tcttttttag tatcgataat
     3121 tgttgtttta catgaaatag gagtgtaaaa catatggaaa atttagcagt aaatataaca
     3181 aatctacaag tcagctttgg caaccagcta gaactatcta ttgattctct tcgtgtctat
     3241 cagcaagatc gtatagggat cataggagaa aatggtgtcg gtaaatcgac tttgctcaaa
     3301 ctaatagccg gtgaactttt tcccgatcat gggaaaatcc aaacagagat caccttcaac
     3361 tacctgcctc aattaaccta tctcgctgaa gcaaaggacc taaatttgga attagccagt
     3421 catttccagt taagactgga agaaacttca gagcggaaat ggagcggagg ggaagaacga
     3481 aagatcgagt tgatacgtct tctttcttct tatgaacaag ggatgcttct agacgagcca
     3541 acaacccatc tagatagaaa aagtattgat cgactgattg aagagcttcg ttattattat
     3601 ggtacgctgg tttttgttag tcatgatcgc tattttctag atgagctagc atcgaaaatc
     3661 tgggaagtaa aagacggaga aatccgagag ttttcgggga attatagtgc ctatctcact
     3721 caaaaggaat tggagaaaaa gactcagcta cgagaagcag agtcgatcat gaaagagaaa
     3781 aaacgattgg aaaaatcgat ccaagaaaag aaaaaacaag cggaaaagtt ggaaaaagtg
     3841 tccagtaaaa agaaaaagca acaaatcaga ctggatcggt tgtcttcctc taaacaaaaa
     3901 gacagtgtac aaaaagccat ccaaaagaat gcgaaaacat tagagagaag actccaaaaa
     3961 ataggagaaa caaccaagcc gcagcagatg aaacaaatcc gttttccagt accaaaatct
     4021 cttgaactcc acagccgcta tcccatcatg ggacaaaatg tccaattgga aagaagtggg
     4081 agaacattac tggtaaatgg tgattttcag ttttctttag gtaaaaaaat cgcgattgtc
     4141 ggtgaaaatg gttcaggtaa gacaacctta ttagaacata tccgcaaaca aggagaagga
     4201 atccttctct ctccgaaagt aagctttcaa gtatatcagc aaaagggtta tcaaatgaca
     4261 tctgaagaat ccatcattcg ttttgtcatg agacaaacag agttttcaga atcgcttgtc
     4321 cgtagtttgc tgaatcactt agggtttgct caggaaactt tgacgaaacc gttatgtaca
     4381 ttaagtgggg gagaagcgac ccgtctgacg attgctttgc tttttactaa gccaagtaat
     4441 gtgttgctgt tagatgaacc gactaatttt attgatatgg caacgatcga agctttagag
     4501 aagctaatgc aaatatatcc gggaacgatt ttgtttactt ctcatgattc ttactttgtc
     4561 gagcgtacgg ctgatgaagt ttatgaaata aaagggcaga aaataaaaaa agtacttacg
     4621 agaaattttt aaatgtgcta cgatgatttt cgtgacaaat ttaaaggagt ggtacagatt
     4681 gcctacaaat aaaaaagaag gaataatttt tacaacaatg atgtgttttt tgatggtctt
     4741 ggggatgagc gcgtataatt tatggctgca tcaagatctt catttatcaa gtttgttgat
     4801 tggtctagtg cctggattcg tggtggcttt cattttggat gtcttcatca tcggtgtgct
     4861 ggcgaaaaaa attgccttta aactaccagt aaatccagaa agcaaggtcc aaatgatctt
     4921 aactatttca tgcttgatgg ttttaggaat ggtgacatgt atgtctttat tcggtgtgat
     4981 catggaacaa ggaatacctg atcaattatt ctctgcttat atgaatgctt ggaaaatgaa
     5041 tgtgattgcc gctttaccgt tgcagttgat catcgttggc ccgctttcaa gaagtgtgct
     5101 aaaagcaatt caaagtaatg aatgatggaa cactgttatt tgaaaaaagg ccttggcatg
     5161 ctttttgtca tagtctcttg aatgcagttc tagaaaaata gtgatccgaa cgataggttt
     5221 tggcctgtcg ttcggatcgc tttttctttt ccaactgtat tgctctttta ttgaagataa
     5281 tttgctc
//
LOCUS       DAZKCH010000289         5079 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.129, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000289 DAZKCH010000000
VERSION     DAZKCH010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.129"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            260..1171
                     /locus_tag="ACG84X_003063"
     CDS             260..1171
                     /locus_tag="ACG84X_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFP9128818.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACG84X_003064"
     CDS             1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACG84X_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFP9128819.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            2328..2612
                     /locus_tag="ACG84X_003065"
     CDS             2328..2612
                     /locus_tag="ACG84X_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9128820.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            2978..3277
                     /locus_tag="ACG84X_003066"
     CDS             2978..3277
                     /locus_tag="ACG84X_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128821.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            3320..4810
                     /locus_tag="ACG84X_003067"
     CDS             3320..4810
                     /locus_tag="ACG84X_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFP9128822.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
BASE COUNT         1871 a          745 c          952 g         1511 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccc ccattgtcaa caggcagttc
       61 agcctcgtta aattcagcat gggtatcact tatgaaaatt catctacatt ggtgataata
      121 gtaaatccag tagggcgaaa taattgactg taatttacgg ggcaaaacgg cacaatctca
      181 aacgagattg tgccgtttaa ggggaagatt ctagaaatat ttcatacttc caactatata
      241 gttaaggagg agactgaaaa tgaagaagtt gtttttttta ttgttattgt tattcttaat
      301 atacttaggt tatgactacg ttaatgaagc actgttttct caggaaaaag tcgaatttca
      361 aaattatgat caaaatccca aagaacattt agaaaatagt gggacttctg aaaataccca
      421 agagaaaaca attacagaag aacaggttta tcaaggaaat ctgctattaa tcaatagtaa
      481 atatcctgtt cgccaagaaa gtgtgaagtc agatatcgtg aatttatcta aacatgacga
      541 attaataaat ggatacgggt tgcttgatag taatatttat atgtcaaaag aaatagcaca
      601 aaaattttca gagatggtca atgatgctgt aaagggtggc gttagtcatt ttattattaa
      661 tagtggctat cgagactttg atgagcaaag tgtgctttac caagaaatgg gggctgagta
      721 tgccttacca gcaggttata gtgagcataa ttcaggttta tcactagatg taggatcaag
      781 cttgacgaaa atggaacgag cccctgaagg aaagtggata gaagaaaatg cttggaaata
      841 cgggttcatt ttacgttatc cagaggacaa aacagagtta acaggaattc aatatgaacc
      901 atggcatatt cgctatgttg gtttaccaca tagtgcgatt atgaaagaaa agaatttcgt
      961 tctcgaggaa tatatggatt acctaaaaga agaaaaaacc atttctgtta gtgtaaatgg
     1021 ggaaaaatat gagatctttt attatcctgt tactaaaaat accaccattc atgtgccgac
     1081 taatcttcgt tatgagatat caggaaacaa tatagacggt gtaattgtga cagtgtttcc
     1141 cggatcaaca catactaatt caaggaggta aggatggcgg aatgaaacca acgaaattaa
     1201 tgaacagcat tattgtacta gcacttttgg ggtaacgtta gctttttaat ttaaaaccca
     1261 cgttaactag gacattgcta tactaatgat acaacttaaa caaaagaatt agaggaaatt
     1321 atattgggaa aaatattatc tagaggattg ctagctttat atttagtgac actaatctgg
     1381 ttagtgttat tcaaattaca atacaatatt ttatcagtat ttaattatca tcaaagaagt
     1441 cttaacttga ctccatttac tgctactggg aatttcagag agatgataga taatgttata
     1501 atctttattc catttggctt gcttttgaat gtcaatttta aagaaatcgg atttttacct
     1561 aagtttgctt ttgtactggt tttaagtctt acttttgaaa taattcaatt tatcttcgct
     1621 attggagcga cagacataac agatgtaatt acaaatactg ttggaggctt tcttggactg
     1681 aaattatatg gtttaagcaa taagcatatg aatcaaaaaa aattagacag agttattatt
     1741 tttgtaggta tacttttgct cgtattattg ctcgtttacc gtacccattt aagaataaat
     1801 tacgtgtaag atgtctaaat caagcaatct gatctttcat acacataaag atattgaatg
     1861 aattggatta gatggaaaac gggatgtggg gaaactcgcc cgtaggtgtg aagtgagggg
     1921 aaaaccggtg ataaagtaaa aagcttacct aacactatag taacaaagaa agcccaatta
     1981 tcaattttag tgctgaggaa ttggtctctt taataaattt ccttaacgtt gtaaatccgc
     2041 attttcctga cggtaccccc actagcagcc atgctttttt tgaatctttg taggacgttt
     2101 taaagagaat tacccacttt aaaattaaac atgcgcttag aatcgcttta ggaaacacga
     2161 tccagtccaa taatcgtcga taaaaacttt tgaaaaaggt tggtgaaatt acctactttt
     2221 ggaataatca caaatcacaa gtgattaatc acttgtttat taagatatta aaagctataa
     2281 tttaaataaa gcgtgaattt tattacacaa aaagaggggg gagaaacttg gaactagcat
     2341 ttagagaaag cttaaaaaag atgagaggta ccaaatcaaa agaaaaattc tcccaagaat
     2401 tagaaatgag tagatcaaat tattcacgaa tagaatcagg aaaatcagat ccaaccataa
     2461 aaacactaga acaaattgca aagttaacta actcaacgct agtagtggat ttaatcccaa
     2521 atgagccaac agaaccagaa ccagaaacag aatcagaaca agtaacattg gatttagaaa
     2581 tggaagaaga aaaaagcaat gacttcgtgt gaataatgca cgaaatcgtt gcttattttt
     2641 tttaaaagcg gtatactaga tataacgaaa caacgaactg aatagaaacg aaaaaagagc
     2701 catgacacat ttataaaatg tttgacgaca ttttataaat gcatagcccg ataagattgc
     2761 caaaccaacg cttatcagtt agtcagatga actcttccct cgtaagaagt tatttaatta
     2821 actttgtttg aagacggtat ataaccgtac tatcattata tagggaaatc agagagtttt
     2881 caagtatcta agctactgaa tttaagaatt gttaagcaat caatcggaaa tcgtttgatt
     2941 gctttttttg tattcattta tagaaggtgg agtttgtatg aatcatgatg aatgtaaaac
     3001 ttatataaaa aatagtttat tggagataag aaaattagca aatatctata cactagaaac
     3061 gtttaagaaa gagttagaaa agagaaatat ctacttagaa acaaaatcag ataagtattt
     3121 ttcttcggag ggggaagatt atatatataa gttaatagaa aataacaaaa taatttattc
     3181 gattagtgga aaaaaattga cttataaagg aaaaaaatct ttttcaaaac atgcaatatt
     3241 gaaacagttg aatgaaaaag caaaccaagt taattaaaca acctatttta taggatttat
     3301 aggaaaggag aacagctgaa tgaatatccc ttttgttgta gaaactgtgc ttcatgacgg
     3361 cttgttaaag tacaaattta aaaatagtaa aattcgctca atcactacca agccaggtaa
     3421 aagcaaaggg gctatttttg cgtatcgctc aaaatcaagc atgattggcg gtcgtggtgt
     3481 tgttctgact tccgaggaag cgattcaaga aaatcaagat acatttacac attggacacc
     3541 caacgtttat cgttatggaa cgtatgcaga cgaaaaccgt tcatacacga aaggacattc
     3601 tgaaaacaat ttaagacaaa tcaatacctt ctttattgat tttgatattc acacggcaaa
     3661 agaaactatt tcagcaagcg atattttaac aaccgctatt gatttaggtt ttatgcctac
     3721 tatgattatc aaatctgata aaggttatca agcatatttt gttttagaaa cgccagtcta
     3781 tgtgacttca aaatcagaat ttaaatctgt caaagcagcc aaaataattt cgcaaaatat
     3841 ccgagaatat tttggaaagt ctttgccagt tgatctaacg tgtaatcatt ttggtattgc
     3901 tcgcatacca agaacggaca atgtagaatt ttttgatcct aattaccgtt attctttcaa
     3961 agaatggcaa gattggtctt tcaaacaaac agataataag ggctttactc gttcaagtct
     4021 aacggtttta agcggtacag aaggcaaaaa acaagtagat gaaccctggt ttaatctctt
     4081 attgcacgaa acgaaatttt caggagaaaa gggtttaata gggcgtaata acgtcatgtt
     4141 taccctctct ttagcctact ttagttcagg ctattcaatc gaaacgtgcg aatataatat
     4201 gtttgagttt aataatcgat tagatcaacc cttagaagaa aaagaagtaa tcaaaattgt
     4261 tagaagtgcc tattcagaaa actatcaagg ggctaatagg gaatacatta ccattctttg
     4321 caaagcttgg gtatcaagtg atttaaccag taaagattta tttgtccgtc aagggtggtt
     4381 taaattcaag aaaaaaagaa gcgaacgtca acgtgttcat ttgtcagaat ggaaagaaga
     4441 tttaatggct tatattagcg aaaaaagcga tgtatacaag ccttatttag tgacgaccaa
     4501 aaaagagatt agagaagtgc taggcattcc tgaacggaca ttagataaat tgctgaaggt
     4561 actgaaggcg aatcaggaaa ttttctttaa gattaaacca ggaagaaatg gtggcattca
     4621 acttgctagt gttaaatcat tgttgctatc gatcattaaa gtaaaaaaag aagaaaaaga
     4681 aagctatata aaggcgctga caaattcttt tgacttagag catacattca ttcaagagac
     4741 tttaaacaag ctagcagaac gccctaaaac ggacacacaa ctcgatttgt ttagctatga
     4801 tacaggctga aaataaaacc cgcactatgc cattacattt atatctatga tacgtgtttg
     4861 ttttttcttt gctgtttagc gaatgattag cagaaatata cagagtaaga ttttaattaa
     4921 ttattagggg gagaaggaga gagtagcccg aaaactttta gttggcttgg actgaacgaa
     4981 gtgagggaaa ggctactaaa acgtcgaggg gcagtgagag cgaagcgaac acttgatttt
     5041 ttaacagaat taggcagaag tcgcccatcc tctataggt
//
LOCUS       DAZKCH010000290         4802 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.136, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000290 DAZKCH010000000
VERSION     DAZKCH010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.136"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            90..785
                     /gene="vanR-A"
                     /locus_tag="ACG84X_003068"
     CDS             90..785
                     /gene="vanR-A"
                     /locus_tag="ACG84X_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFP9128823.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            763..1917
                     /locus_tag="ACG84X_003069"
     CDS             763..1917
                     /locus_tag="ACG84X_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFP9128824.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2132..3100
                     /locus_tag="ACG84X_003070"
     CDS             2132..3100
                     /locus_tag="ACG84X_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFP9128825.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3093..4124
                     /gene="vanA"
                     /locus_tag="ACG84X_003071"
     CDS             3093..4124
                     /gene="vanA"
                     /locus_tag="ACG84X_003071"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFP9128826.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4130..4738
                     /locus_tag="ACG84X_003072"
     CDS             4130..4738
                     /locus_tag="ACG84X_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFP9128827.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1481 a          921 c         1119 g         1281 t
ORIGIN      
        1 tggcctttta tcttttacac aattatatgg actttatcct ataatctgat aaattattaa
       61 gggcaaactt atgtgaaagg gtgataacta tgagcgataa aatacttatt gtggatgatg
      121 aacatgaaat tgccgatttg gttgaattat acttaaaaaa cgagaattat acggttttca
      181 aatactatac cgccaaagaa gcattggaat gtatagacaa gtctgagatt gaccttgcca
      241 tattggacat catgcttccc ggcacaagcg gccttactat ctgtcaaaaa ataagggaca
      301 agcacaccta tccgattatc atgctgaccg ggaaagatac agaggtagat aaaattacag
      361 ggttaacaat cggcgcggat gattatataa cgaagccctt tcgcccactg gagttaattg
      421 ctcgggtaaa ggcccagttg cgccgataca aaaaattcag tggagtaaag gagcagaacg
      481 aaaatgttat cgtccactcc ggccttgtca ttaatgttaa cacccatgag tgttatctga
      541 acgagaagca gttatccctt actcccaccg agttttcaat actgcgaatc ctctgtgaaa
      601 acaaggggaa tgtggttagc tccgagctgc tatttcatga gatatggggc gacgaatatt
      661 tcagcaagag caacaacacc atcaccgtgc atatccggca tttgcgcgaa aaaatgaacg
      721 acaccattga taatccgaaa tatataaaaa cggtatgggg ggttggttat aaaattgaaa
      781 aataaaaaaa acgactattc caaactagaa cgaaaacttt acatgtatat cgttgcaatt
      841 gttgtggtag caattgtatt cgtgttgtat attcgttcaa tgatccgagg gaaacttggg
      901 gattggatct taagtatttt ggaaaacaaa tatgacttaa atcacctgga cgcgatgaaa
      961 ttatatcaat attccatacg gaacaatata gatatcttta tttatgtggc gattgtcatt
     1021 agtattctta ttctatgtcg cgtcatgctt tcaaaattcg caaaatactt tgacgagata
     1081 aataccggca ttgatgtact tattcagaac gaagataaac aaattgagct ttctgcggaa
     1141 atggatgtta tggaacaaaa gctcaacaca ttaaaacgga ctctggaaaa gcgagagcag
     1201 gatgcaaagc tggccgaaca aagaaaaaat gacgttgtta tgtacttggc gcacgatatt
     1261 aaaacgcccc ttacatccat tatcggttat ttgagcctgc ttgacgaggc tccagacatg
     1321 ccggtagatc aaaaggcaaa gtatgtgcat atcacgttgg acaaagcgta tcgactcgaa
     1381 cagctaatcg acgagttttt tgagattaca cggtataacc tacaaacgat aacgctaaca
     1441 aaaacgcaca tagacctata ctatatgctg gtgcagatga ccgatgaatt ttatcctcag
     1501 ctttccgcac atggaaaaca ggcggttatt cacgcccccg aggatctgac cgtgtccggc
     1561 gaccctgata aactcgcgag agtctttaac aacattttga aaaacgccgc tgcatacagt
     1621 gaggataaca gcatcattga cattaccgcg ggcctctccg gggatgtggt gtcaatcgaa
     1681 ttcaagaaca ctggaagcat cccaaaagat aagctagctg ccatatttga aaagttctat
     1741 aggctggaca atgctcgttc ttccgatacg ggtggcgcgg gacttggatt ggcgattgca
     1801 aaagaaatta ttgttcagca tggagggcag atttacgcgg aaagcaatga taactatacg
     1861 acgtttaggg tagagcttcc agcgatgcca gacttggttg ataaaaggag gtcctaagag
     1921 atgtatataa ttttttagga aaatctcaag gttatcttta ctttttctta ggaaattaac
     1981 aatttaatat taagaaacgg ctcgttctta cacggtagac ttaataccgt aagaacgagc
     2041 cgttttcgtt cttcagagaa agatttgaca agattaccat tggcatcccc gttttatttg
     2101 gtgcctttca cagaaagggt tggtcttaat tatgaataac atcggcatta ctgtttatgg
     2161 atgtgagcag gatgaggcag atgcattcca tgctctttcg cctcgctttg gcgttatggc
     2221 aacgataatt aacgccaacg tgtcggaatc caacgccaaa tccgcgcctt tcaatcaatg
     2281 tatcagtgtg ggacataaat cagagatttc cgcctctatt cttcttgcgc tgaagagagc
     2341 cggtgtgaaa tatatttcta cccgaagcat cggctgcaat catatagata caactgctgc
     2401 taagagaatg ggcatcactg tcgacaatgt ggcgtactcg ccggatagcg ttgccgatta
     2461 tactatgatg ctaattctta tggcagtacg caacgtaaaa tcgattgtgc gctctgtgga
     2521 aaaacatgat ttcaggttgg acagcgaccg tggcaaggta ctcagcgaca tgacagttgg
     2581 tgtggtggga acgggccaga taggcaaagc ggttattgag cggctgcgag gatttggatg
     2641 taaagtgttg gcttatagtc gcagccgaag tatagaggta aactatgtac cgtttgatga
     2701 gttgctgcaa aatagcgata tcgttacgct tcatgtgccg ctcaatacgg atacgcacta
     2761 tattatcagc cacgaacaaa tacagagaat gaagcaagga gcatttctta tcaatactgg
     2821 gcgcggtcca cttgtagata cctatgagtt ggttaaagca ttagaaaacg ggaaactggg
     2881 cggtgccgca ttggatgtat tggaaggaga ggaagagttt ttctactctg attgcaccca
     2941 aaaaccaatt gataatcaat ttttacttaa acttcaaaga atgcctaacg tgataatcac
     3001 accgcatacg gcctattata ccgagcaagc gttgcgtgat accgttgaaa aaaccattaa
     3061 aaactgtttg gattttgaaa ggagacagga gcatgaatag aataaaagtt gcaatactgt
     3121 ttgggggttg ctcagaggag catgacgtat cggtaaaatc tgcaatagag atagccgcta
     3181 acattaataa agaaaaatac gagccgttat acattggaat tacgaaatct ggtgtatgga
     3241 aaatgtgcga aaaaccttgc gcggaatggg aaaacgacaa ttgctattca gctgtactct
     3301 cgccggataa aaaaatgcac ggattacttg ttaaaaagaa ccatgaatat gaaatcaacc
     3361 atgttgatgt agcattttca gctttgcatg gcaagtcagg tgaagatgga tccatacaag
     3421 gtctgtttga attgtccggt atcccttttg taggctgcga tattcaaagc tcagcaattt
     3481 gtatggacaa atcgttgaca tacatcgttg cgaaaaatgc tgggatagct actcccgcct
     3541 tttgggttat taataaagat gataggccgg tggcagctac gtttacctat cctgtttttg
     3601 ttaagccggc gcgttcaggc tcatccttcg gtgtgaaaaa agtcaatagc gcggacgaat
     3661 tggactacgc aattgaatcg gcaagacaat atgacagcaa aatcttaatt gagcaggctg
     3721 tttcgggctg tgaggtcggt tgtgcggtat tgggaaacag tgccgcgtta gttgttggcg
     3781 aggtggacca aatcaggctg cagtacggaa tctttcgtat tcatcaggaa gtcgagccgg
     3841 aaaaaggctc tgaaaacgca gttataaccg ttcccgcaga cctttcagca gaggagcgag
     3901 gacggataca ggaaacggca aaaaaaatat ataaagcgct cggctgtaga ggtctagccc
     3961 gtgtggatat gtttttacaa gataacggcc gcattgtact gaacgaagtc aatactctgc
     4021 ccggtttcac gtcatacagt cgttatcccc gtatgatggc cgctgcaggt attgcacttc
     4081 ccgaactgat tgaccgcttg atcgtattag cgttaaaggg gtgataagca tggaaatagg
     4141 atttactttt ttagatgaaa tagtacacgg tgttcgttgg gacgctaaat atgccacttg
     4201 ggataatttc accggaaaac cggttgacgg ttatgaagta aatcgcattg tagggacata
     4261 cgagttggct gaatcgcttt tgaaggcaaa agaactggct gctacccaag ggtacggatt
     4321 gcttctatgg gacggttacc gtcctaagcg tgctgtaaac tgttttatgc aatgggctgc
     4381 acagccggaa aataacctga caaaggaaag ttattatccc aatattgacc gaactgagat
     4441 gatttcaaaa ggatacgtgg cttcaaaatc aagccatagc cgcggcagtg ccattgatct
     4501 tacgctttat cgattagaca cgggtgagct tgtaccaatg gggagccgat ttgattttat
     4561 ggatgaacgc tctcatcatg cggcaaatgg aatatcatgc aatgaagcgc aaaatcgcag
     4621 acgtttgcgc tccatcatgg aaaacagtgg gtttgaagca tatagcctcg aatggtggca
     4681 ctatgtatta agagacgaac cataccccaa tagctatttt gatttccccg ttaaataaac
     4741 ttttaaccgt tgcacggaca aacggttctg ttgcaaagtt ttaaataaag aataaaatcc
     4801 ct
//
LOCUS       DAZKCH010000291         3278 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.156, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000291 DAZKCH010000000
VERSION     DAZKCH010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.156"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            3..188
                     /locus_tag="ACG84X_003073"
     CDS             3..188
                     /locus_tag="ACG84X_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9128828.1"
                     /translation="MNISVSELARRIGQTPQNFNKKLQRETVTLDELKAIADVLGVKF
                     VQAFILPDGEEIKISNE"
     gene            203..1072
                     /locus_tag="ACG84X_003074"
     CDS             203..1072
                     /locus_tag="ACG84X_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFP9128829.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1053..1787
                     /locus_tag="ACG84X_003075"
     CDS             1053..1787
                     /locus_tag="ACG84X_003075"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9128830.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            1820..2728
                     /locus_tag="ACG84X_003076"
     CDS             1820..2728
                     /locus_tag="ACG84X_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFP9128831.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            2725..3205
                     /locus_tag="ACG84X_003077"
                     /pseudo
     CDS             2725..3205
                     /locus_tag="ACG84X_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1146 a          465 c          718 g          949 t
ORIGIN      
        1 aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca cagaatttca
       61 ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt gctgatgtgc
      121 taggtgtcaa gtttgtgcag gcatttattt taccagatgg agaagaaata aaaatatcta
      181 acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa cagagaaatt
      241 atcatctttg ccttttatag aaggcatcgt attagggggc tcacgtgcaa gaggcaccca
      301 tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat ttgacctgac
      361 agcgattaat caaattgcta cagaattgga tgataaaaat agaaacaacc ttgttgtgcc
      421 tcccggagcg tggggtgatt ggattaatgg cggcggatgg ttatttataa atgggtatca
      481 tgttgacttg attttacgtg atataaaacg ggtagaacaa ataatcaaag atacggagca
      541 aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa gtgcaatgta
      601 tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct tatgcgaatt
      661 aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga acttttttat
      721 atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggtag aggataaata
      781 ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac tatttgcatg
      841 taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa cttttgaata
      901 taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg gtctttctct
      961 ttttgaatgc tacgatatga ccgagaaact ttataaagaa gtgaatgaaa ttgtatcgga
     1021 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     1081 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     1141 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     1201 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     1261 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     1321 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     1381 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     1441 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     1501 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     1561 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     1621 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     1681 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     1741 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     1801 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     1861 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     1921 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     1981 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     2041 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     2101 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     2161 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     2221 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     2281 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     2341 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     2401 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     2461 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     2521 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     2581 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     2641 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     2701 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     2761 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     2821 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     2881 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     2941 ataatatatc ttttatatag aagatatcgc cgtatgtaag gatttcaggg ggcaaggcat
     3001 aggcagcgcg cttatcaata tatctataga atgggcaaag cataaaaact tgcatggact
     3061 aatgcttgaa acccaggaca ataaccttat agcttgtaaa ttctatcata attgtggttt
     3121 caaaatcggc tccgtcgata ctatgttata cgccaacttt gaaaacaact ttgaaaaagc
     3181 tgttttctgg tatttaaggt tttagaatgc aaggaacagt gaattggagt tcgtcttgtg
     3241 gttctgttgc aaagttttaa ataaagaata aaatccct
//
LOCUS       DAZKCH010000292         2603 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.175, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000292 DAZKCH010000000
VERSION     DAZKCH010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.175"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            104..796
                     /locus_tag="ACG84X_003078"
     CDS             104..796
                     /locus_tag="ACG84X_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFP9128832.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1123..1620
                     /gene="dfrG"
                     /locus_tag="ACG84X_003079"
     CDS             1123..1620
                     /gene="dfrG"
                     /locus_tag="ACG84X_003079"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFP9128833.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1692..>2603)
                     /locus_tag="ACG84X_003080"
     CDS             complement(1692..>2603)
                     /locus_tag="ACG84X_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFP9128834.1"
                     /translation="HLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSR
                     FVDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHH
                     FICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHE
                     EAISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHST
                     NSFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSA
                     DKKVLTPAQRLGITDKQFDWKDIIYFK"
BASE COUNT          963 a          383 c          467 g          790 t
ORIGIN      
        1 gtatttatat taaaattaca tatgtaattt aaaaacgctt gacattgtgt ttgagatcac
       61 ttacttttag catgtaaaag tattggatta aggagctatg caaatgaaaa agaaatttat
      121 tactggtggg attgtcgttg catttctatg tctaattggc tacacaggca cgcggtacgc
      181 aaatgaaatt attttgtggg gtggagagac agatattgat acaatcaatg agaatctgac
      241 acagcttgat catacattga cagataaaga gcaagcgatt acagatctta ccgctcgact
      301 agcacaaaaa gaacagacat tgcaagattc aaaggcagat gtccaagaat accaaacaaa
      361 agtaaatgaa ttagaaaacc aaaaaaatca atcggcagca gaaaaacaaa acttagaaag
      421 tcaattagtc agcaaggatg cacaactaca aagcaaacaa aatgaaatca atgtcaaact
      481 agatgagatc aaccaaaaaa atgatgaaat caatcatctg aatgcagatt ggacagcaag
      541 actacaagaa gcacaagcaa aactttcaga attacaaaat actgtaaatg gtttgaatca
      601 acaaatcgca acactgacac aagaaaaaac aaatgtagaa actcagttaa cagatacaca
      661 aaagaaatta gacgaagcaa ctgctgaaaa ctcaagcttg aaacaatata ttcaaaagtt
      721 agaaaaagca aaagatgaag tggaagatac agctgataaa tctcagcaaa ttgttgaaga
      781 acatttgcgt aaataatctt tcttaacaag taaacctaaa ttagtaaaga agcaacagta
      841 atctatacta agtagttcag ttttggagta caaaatgaca aaatgtactt caaaatggac
      901 tacttttttc attttaactt acataccaaa ttacatacaa aatgatttat aaaatgcaat
      961 tgaaaatgat aattgaatga aaatttgtga ttttgtggta ttatgataat ataacttata
     1021 gaaaaaattg cttattcaac taacgggcag gataatgaga aaaggttttt tgatagaaat
     1081 aagaaattag atggtaaatt agttaaaaag gctgtgttat aaatgaaagt ttctttgatt
     1141 gctgcgatgg ataagaatag agtgattggc aaagagaatg acattccttg gaggattccc
     1201 aaggactggg aatatgttaa aaatactaca aagggacatc cgataatatt aggtaggaag
     1261 aaccttgaat caatcggaag agccttacct gacagaagaa atattattct gacgagagat
     1321 aaggggttta cctttaatgg ttgtgaaatt gttcattcaa tagaagatgt ttttgagtta
     1381 tgtaaaaacg aagaagaaat ttttattttc ggaggagaac agatttataa tttgtttttc
     1441 ccttatgttg agaaaatgta catcacaaaa atacatcatg aattcgaagg agatactttt
     1501 tttccagaag tgaattatga ggaatggaat gaggtatttg cccaaaaagg gataaagaat
     1561 gataaaaatc cgtataacta ctattttcat gtatatgaaa gaaaaaactt attgagttaa
     1621 cgggtgcgtt aattgaagaa gaacagtaaa gataaagcac aagagcttgg gattactcca
     1681 agctcttttt gtcatttgaa ataaattata tctttccaat caaattgttt atctgtaatc
     1741 cctaatcttt gagcaggtgt caaaaccttt ttatccgctg atttaaaagg gcgacaaaag
     1801 ttgtagtaag ttcttagaat tgtaatcgca aattgagcat acttcggatt gaagttagcg
     1861 taaatatagc tcttcttatc accacgagct gttgttaatg gtctttcaag agatgatata
     1921 taacgtctta tctgttgaat aaagctattg gtcgaatggt cattaacatt taatagcatc
     1981 tttgcgattt cgtttggttc cagagcagat aaatccgttc tacaatcaac tgaataaaat
     2041 cctttatcct tagtggctaa tggatgtttg atagggttat cggcatattt gcgatatctt
     2101 tctccatctt tactaatagc ctcttcgtgg aattgatgac ttgttagtaa ttcagttaga
     2161 taatgagatg ccaaagtccg tagaaacttt gttttgaatc ctctgatatc tccccaatcg
     2221 agcagttctg cttttgcttg tccgaattct tttaagcatt gttttctgct tttcgtcttg
     2281 ttaacttggc aaataaaatg atgtgcatcg ctcaacctta attctttcgt gaatactcta
     2341 taaaaggcgt ttctaataga gaagtcatca tcactaatca ttcgccattc gtcggcatta
     2401 accatttgtt taattaacca atagtgagca gttgtagtat aaggagcatc aacatttaaa
     2461 ccatcgacaa atctactcct attagtaatt ttccctaatt cgtgaagata agcattccta
     2521 ttttcgctat cgttagcgga tggttcttgt ggataataag accaatctaa cctatcattt
     2581 ttacgactaa aagtattgag atg
//
LOCUS       DAZKCH010000293         1073 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.225, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000293 DAZKCH010000000
VERSION     DAZKCH010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.225"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            126..863
                     /gene="erm(B)"
                     /locus_tag="ACG84X_003081"
     CDS             126..863
                     /gene="erm(B)"
                     /locus_tag="ACG84X_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFP9128835.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
BASE COUNT          388 a          187 c          175 g          323 t
ORIGIN      
        1 tggcctttta tcttttacac aattatatgg actttatcga ctttttaaac agataactaa
       61 aattacaaac aaatcgttta acttctgtat ttgtttatag atgtaatcac ttcaggagag
      121 attacatgaa caaaaatata aaatattctc aaaacttttt aacgagtgaa aaagtactca
      181 accaaataat aaaacaattg aatttaaaag aaaccgatac cgtttacgaa attggaacag
      241 gtaaagggca tttaacgacg aaactggcta aaataagtaa acaggtaacg tctattgaat
      301 tagacagtca tctattcaac ttatcgtcag aaaaattaaa actgaatact cgtgtcactt
      361 taattcacca agatattcta cagtttcaat tccctaacaa acagaggtat aaaattgttg
      421 ggaatattcc ttaccattta agcacacaaa ttattaaaaa agtggttttt gaaagccgtg
      481 cgtctgacat ctatctgatt gttgaagaag gattctacaa gcgtaccttg gatattcacc
      541 gaacactagg gttgctcttg cacactcaag tctcgattca gcaattgctt aagctgccag
      601 cggaatgctt tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt acccgccata
      661 ccacagatgt tccagataaa tattggaagc tatatacgta ctttgtttca aaatgggtca
      721 atcgagaata tcgtcaactg tttactaaaa atcagtttca tcaagcaatg aaacacgcca
      781 aagtaaacaa tttaagtacc attacttatg agcaagtatt gtctattttt aatagttatc
      841 tattatttaa cgggaggaaa taattctatg agtcgctttt ttaaatttgg aaagttacac
      901 gttactaaag ggaatggaga taaattatta gatatactac tgacagcttc caagaagcta
      961 aagaggtccc tagcgcctac ggggaatttg tatcgataag gggtacaaat tcccactaag
     1021 cgctcgggac cccttgtagg aaaatgtcct aagtgtggca acaatattgt att
//
LOCUS       DAZKCH010000294          994 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.233, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000294 DAZKCH010000000
VERSION     DAZKCH010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.233"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..431
                     /locus_tag="ACG84X_003082"
                     /pseudo
     CDS             82..431
                     /locus_tag="ACG84X_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(703..993)
                     /locus_tag="ACG84X_003083"
     CDS             complement(703..993)
                     /locus_tag="ACG84X_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9128836.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT          306 a          198 c          149 g          341 t
ORIGIN      
        1 ttcttatatt tcctaataga gtataacata gctttaagca ttacttaaag ataacttaaa
       61 agttatcttt taaatactta attgttaaat accttatttg atgcaaaaga aatctacgat
      121 agtcaacaaa aaaattttca ttatatccag aaaaattttt cttagttaag gacctatgga
      181 ttgcagtaat gcagaattcg tcgaataaac tgccaaagac atacaatcat attgctttta
      241 aaattgacga acaagatata gattcgtttg tctcaaaaat ccaaatgtta ggtttaactg
      301 tcgaaccagg acgttctcgt gtgaaaggcg aggcttcttc aatttacttt tacgactatg
      361 ataatcacct cttcgagtta cataccggta ctctccagga acgtttaaaa tcctacaatt
      421 ccactacctg agactagtaa tgactagtct ctttttatgg cctctgatcc ccccattgag
      481 cgaatactaa tagggcttcg aattgatctg ttcaatcttt aagcaatatc cctcaaatga
      541 gtttggaaag tttagtgatt catcacaaat acttaaatac atgtagttat atatagattg
      601 aggttcttgt gagcgtatgc tcgtgtgggt tcaaatccca tcgtctgcat ccatctttcc
      661 aaaacaagcg gctaggacat ttttgtctca gccgcttgtt ttctagttta ttctttcatc
      721 ttgtcggacc ttttttcttg ggtatagact tttctcatat tctaccacaa ttttgggttt
      781 ccctaacaca tgataggatc tcacaacaaa ttgctttcta ttattataat aacctgtaac
      841 gactaacttc atcccttcgt ctacttcagc taggaagttc aaactatggg aagcaatcaa
      901 acaattgacc ccatttaaac tgaaacggat caacggtctg gcactaactt gcaaagtacg
      961 gatcttatct actgttccat attttttctc cata
//
LOCUS       DAZKCH010000295          912 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4285
            SAMEA115707077-rid22582623.guided.238, whole genome shotgun
            sequence.
ACCESSION   DAZKCH010000295 DAZKCH010000000
VERSION     DAZKCH010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707077
            Sequence Read Archive: ERR13196809
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287870.1
            Genome Coverage       :: 120x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:30:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,084
            CDSs (total)                      :: 3,024
            Genes (coding)                    :: 2,925
            CDSs (with protein)               :: 2,925
            Genes (RNA)                       :: 60
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 99
            CDSs (without protein)            :: 99
            Pseudo Genes (ambiguous residues) :: 0 of 99
            Pseudo Genes (frameshifted)       :: 41 of 99
            Pseudo Genes (incomplete)         :: 53 of 99
            Pseudo Genes (internal stop)      :: 24 of 99
            Pseudo Genes (multiple problems)  :: 16 of 99
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707077-rid22582623.guided.238"
                     /isolate="VRE4285"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            7..654
                     /locus_tag="ACG84X_003084"
     CDS             7..654
                     /locus_tag="ACG84X_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-7 chloramphenicol O-acetyltransferase"
                     /protein_id="HFP9128837.1"
                     /translation="MTFNIIELENWDRKEYFEHYFNQQTTYSITKEIDITLFKDMIKK
                     KGYEIYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWT
                     ESDKNFISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNS
                     SFLLPIITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDIIHRVDDWI"
BASE COUNT          335 a          101 c          138 g          338 t
ORIGIN      
        1 ttatatatga cttttaatat tattgaatta gaaaattggg atagaaaaga atattttgaa
       61 cactatttta atcagcaaac tacttatagc attactaaag aaattgatat tactttgttt
      121 aaagatatga taaaaaagaa aggatatgaa atttatccct ctttaattta tgcaattatg
      181 gaagttgtaa ataaaaataa agtgtttaga acaggaatta atagtgagaa taaattaggt
      241 tattgggata agttaaatcc tttgtataca gtttttaata agcaaactga aaaatttact
      301 aacatttgga ctgaatctga taaaaacttc atttcttttt ataataatta taaaaatgac
      361 ttgcttgaat ataaagataa agaagaaatg tttcctaaaa aaccgatacc tgaaaacacc
      421 ataccgattt caatgattcc ttggattgat tttagttcat ttaatttaaa tattggtaac
      481 aatagcagct ttttattgcc tattattacg ataggtaaat tttatagtga gaataataaa
      541 atttatatac cagttgctct gcaacttcat cattctgtat gtgatggtta ccatgcttca
      601 ctatttatga atgaatttca agatataatt catagggtag atgattggat ttagttttta
      661 gattttgaaa gtgaatttaa ttttatacac gtaagtgatc ataaaattta tgaacgtata
      721 acaaccacat tttttggttg cttgtggttt tgattttgaa tttggttttg aacttatgga
      781 ctgatttatt cagtccattt tttgtgcttg cacaaaaact agcctcgcag agcacacgca
      841 ttaatgactt atgaaacgta gtaaataagt ctagtgtgtt atactttact tggaagatgc
      901 accgaataaa aa
//
